FedInvent™ Patents
Patent Details for Tuesday, February 27, 2024
This page was updated on Thursday, February 29, 2024 at 12:00 AM GMT
Department of Health and Human Services (HHS)
| US 11911012 | Hershey et al. |
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| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio) |
| ASSIGNEE(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio) |
| INVENTOR(S) | Gurjit Khurana Hershey (Cincinnati, Ohio); Jocelyn Biagini-Myers (Cincinnati, Ohio); Eric Schauberger (Cincinnati, Ohio) |
| ABSTRACT | Provided herein are methods and kits for collecting and/or detecting biological materials from the skin of subjects. Methods and kits for determining a biological profile of a target skin site of subjects are also provided herein. |
| FILED | Saturday, March 03, 2018 |
| APPL NO | 16/490438 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/02 (20130101) Original (OR) Class A61B 2503/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6888 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911123 | Iordachita et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Iulian I. Iordachita (Lutherville, Maryland); Jin Seob Kim (Ellicott City, Maryland); David Levi (Baltimore, Maryland); Kevin Cleary (Potomac, Maryland); Reza Monfaredi (Rockville, Maryland) |
| ABSTRACT | A body mountable robot may include a set of stages disposed in a parallel configuration. The body mountable robot may include a set of actuating joints, wherein an actuating joint, of the set of actuating joints, is configured to rotate with respect to a corresponding stage of the set of stages. The body mountable robot may include at least one actuator, wherein the at least one actuator is configured to actuate at least one actuating joint of the set of actuating joints. The body mountable robot may include a set of scissor mechanisms, wherein a scissor mechanism, of the set of scissor mechanisms, that is coupled to the actuating joint, is supported by the corresponding stage, and wherein the scissor mechanism is configured to translate with respect to the corresponding stage. |
| FILED | Monday, November 26, 2018 |
| APPL NO | 16/768508 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/32 (20160201) Original (OR) Class A61B 90/11 (20160201) A61B 2017/3409 (20130101) A61B 2090/374 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911128 | Blaauw et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | David T. Blaauw (Ann Arbor, Michigan); Jamie Phillips (Ann Arbor, Michigan); Cynthia Anne Chestek (Ann Arbor, Michigan); Taekwang Jang (Ann Arbor, Michigan); Hun-Seok Kim (Ann Arbor, Michigan); Dennis Sylvester (Ann Arbor, Michigan); Jongyup Lim (Ann Arbor, Michigan); Eunseong Moon (Ann Arbor, Michigan); Michael Barrow (Ann Arbor, Michigan); Samuel Nason (Ann Arbor, Michigan); Julianna Richie (Ann Arbor, Michigan); Paras Patel (Ann Arbor, Michigan) |
| ABSTRACT | A mote includes an optical receiver that wirelessly receives a power and data signal in form of NIR light energy within a patient and converts the NIR light energy to an electrical signal having a supply voltage. A control module supplies the supply voltage to power devices of the mote. A clock generation circuit locks onto a target clock frequency based on the power and data signal and generates clock signals. A data recovery circuit sets parameters of one of the devices based on the power and data signal and a first clock signal. An amplifier amplifies a neuron signal detected via an electrode inserted in tissue of the patient. A chip identifier module, based on a second clock signal, generates a recorded data signal based on a mote chip identifier and the neuron signal. A driver transmits the recorded data signal via a LED or a RF transmitter. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/173976 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/0017 (20130101) Original (OR) Class A61B 5/0031 (20130101) A61B 5/37 (20210101) A61B 5/384 (20210101) A61B 2560/0219 (20130101) Transmission H04B 10/80 (20130101) H04B 10/114 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911178 | Rottmann et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Markus Rottmann (Chicago, Illinois); Rishi K. Arora (Chicago, Illinois); David A. Johnson (Romeoville, Illinois); Shin Yoo (Wilmette, Illinois) |
| ABSTRACT | A system for treating atrial fibrillation includes a memory configured to store a baseline measurement of an atrial fibrillation characteristic of a patient and a post administration measurement of the atrial fibrillation characteristic of the patient. The post administration measurement is obtained subsequent to administration of a reactive oxygens species (ROS) scavenger to the patient. The system also includes a processor operatively coupled to the memory and configured to determine a change between the baseline measurement and the post administration measurement of the atrial fibrillation characteristic. The processor is further configured to identify, based on the determined change, one or more hot spots of atrial fibrillation, where the one or more hot spots comprise target areas for treatment of the atrial fibrillation. |
| FILED | Wednesday, May 05, 2021 |
| APPL NO | 17/308756 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/339 (20210101) A61B 5/361 (20210101) A61B 5/4848 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911298 | Maitland et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington); The Ohio Willow Wood Company (Mt. Sterling, Ohio) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); The Ohio Willow Wood Company (Mt. Sterling, Ohio) |
| INVENTOR(S) | Murray E. Maitland (Seattle, Washington); Matthew M. Wernke (Seattle, Washington); Evandro M. Ficanha (Seattle, Washington); James M. Colvin (Seattle, Washington) |
| ABSTRACT | A device is provided to allow adaptation of a prosthetic or robotic foot in the medial-lateral direction, including pronation and supination of the foot using a series of articulations. Articulations are permitted in the disclosed device due to linkage systems positioned at various locations of the prosthetic foot. In particular, the device includes multiple connected linkage systems each including upper and lower portions with an articulating contact surface designed for load carriage and stability. The point of contact between the contact surfaces of each linkage system comprises the position-dependent instantaneous center of rotation of the upper portion with respect to the lower portion. The device also includes a platform coupled between the linkage systems and a base. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 17/347785 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/66 (20130101) A61F 2/6607 (20130101) Original (OR) Class A61F 2002/665 (20130101) A61F 2002/5003 (20130101) A61F 2002/5009 (20130101) A61F 2002/5018 (20130101) A61F 2002/5043 (20130101) A61F 2002/5072 (20130101) A61F 2002/6614 (20130101) A61F 2002/6621 (20130101) A61F 2002/6642 (20130101) A61F 2002/6664 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911356 | Xing et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Michael Mingzhao Xing (Clarkesville, Maryland); Rengyun Liu (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to the field of cancer. More specifically, the present invention provides methods and compositions useful for the treatment of cancer characterized by TERT and BRAF mutations. In a specific embodiment, a method for treating a mutant telomerase reverse trancriptase (TERT) enzyme-associated cancer in a subject comprises the step of administering to the subject an anti-cancer agent that inhibits one or more of FOS, GABPB, the formation of the GABPA-GABPB complex or the binding of the GABPA-GABPB complex to a mutant TERT promoter. |
| FILED | Saturday, December 22, 2018 |
| APPL NO | 16/956675 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/196 (20130101) Original (OR) Class A61K 31/423 (20130101) A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/4184 (20130101) A61K 31/4545 (20130101) A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911367 | Kyba et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Michael Kyba (Minneapolis, Minnesota); Darko Bosnakovski (Minneapolis, Minnesota) |
| ABSTRACT | A method for treating a cancer involving one or more translocations generating an oncogenic fusion transcription factor that requires p300/CBP for activity in an animal, comprising administering a compound of formula (I): or a pharmaceutically acceptable salt thereof to the animal. |
| FILED | Thursday, March 10, 2022 |
| APPL NO | 17/691305 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4184 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911369 | Wrobel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Biohaven Therapeutics Ltd. (New Haven, Connecticut) |
| ASSIGNEE(S) | Biohaven Therapeutics Ltd. (Tortola, Virgin Islands) |
| INVENTOR(S) | Jay Edward Wrobel (Lawrenceville, New Jersey); Allen B. Reitz (Lansdale, Pennsylvania); Jeffery Claude Pelletier (Lafayette Hill, Pennsylvania); Garry Robert Smith (Royersford, Pennsylvania); Haiyan Bian (Princeton, New Jersey) |
| ABSTRACT | Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process. |
| FILED | Monday, May 04, 2020 |
| APPL NO | 16/865498 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 9/0056 (20130101) A61K 9/485 (20130101) A61K 9/1617 (20130101) A61K 9/2004 (20130101) A61K 9/2018 (20130101) A61K 9/2063 (20130101) A61K 9/4858 (20130101) A61K 9/4866 (20130101) A61K 31/428 (20130101) Original (OR) Class A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/5377 (20130101) A61K 38/05 (20130101) A61K 38/06 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/28 (20180101) Heterocyclic Compounds C07D 277/82 (20130101) C07D 417/12 (20130101) Peptides C07K 5/0806 (20130101) C07K 5/0808 (20130101) C07K 5/0812 (20130101) C07K 5/06026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911376 | Nagaraj et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| INVENTOR(S) | Ram H. Nagaraj (Aurora, Colorado); Rooban B. Nahomi (Aurora, Colorado); Mi-hyun Nam (Aurora, Colorado) |
| ABSTRACT | Methods of treating, reducing the risk of, preventing, or alleviating at least one symptom of a retinal disease, injury, or condition in a subject involve administering a pharmaceutically effective amount of kynurenic acid to the subject. The kynurenic acid may be administered intravenously or intravitreally. Systems for treating retinal diseases, injuries, or conditions are also disclosed and may include an administration device. |
| FILED | Friday, March 12, 2021 |
| APPL NO | 17/199896 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0048 (20130101) A61K 31/47 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) A61P 27/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911384 | Chilian et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTHEAST OHIO MEDICAL UNIVERSITY (Rootstown, Ohio) |
| ASSIGNEE(S) | NORTHEAST OHIO MEDICAL UNIVERSITY (Rootstown, Ohio) |
| INVENTOR(S) | William M. Chilian (Atwater, Ohio); Vahagn Ohanyan (Hudson, Ohio); Liya Yin (Hudson, Ohio) |
| ABSTRACT | A method for treating or preventing heart failure involving blockage of small blood vessels is described. The method involves administering to a subject in need thereof a therapeutically effective amount of a vasodilator. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/739629 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/353 (20130101) A61K 31/519 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911392 | Shapiro et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Paul S. Shapiro (Baltimore, Maryland); Alexander D. Mackerell, Jr. (Baltimore, Maryland); Jeffrey D. Hasday (Timonium, Maryland) |
| ABSTRACT | Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/740248 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/54 (20130101) A61K 31/5375 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) A61P 29/00 (20180101) A61P 31/00 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911393 | Shapiro et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States of America as represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Paul S. Shapiro (Baltimore, Maryland); Alexander D. Mackerell, Jr. (Baltimore, Maryland); Jeffrey D. Hasday (Timonium, Maryland) |
| ABSTRACT | Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases. |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/169785 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/54 (20130101) A61K 31/5375 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) A61P 29/00 (20180101) A61P 31/00 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911404 | Lau |
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| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| INVENTOR(S) | Eric Lau (Tampa, Florida) |
| ABSTRACT | Disclosed are methods for treating a cancer and/or enhancing immune responses to infiltration of tumors comprising administering to a subject a fucose. Also disclosed herein are methods of detecting the presence of a sugar-modified protein (i.e., a glycosylated protein). |
| FILED | Monday, October 15, 2018 |
| APPL NO | 16/755703 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/7004 (20130101) Original (OR) Class A61K 39/3955 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/5743 (20130101) G01N 2333/70539 (20130101) G01N 2458/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911408 | Laughlin et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF ALASKA FAIRBANKS (Fairbanks, Alaska) |
| ASSIGNEE(S) | UNIVERSITY OF ALASKA FAIRBANKS (Fairbanks, Alaska) |
| INVENTOR(S) | Bernard Laughlin (Fairbanks, Alaska); Kelly Drew (Fairbanks, Alaska) |
| ABSTRACT | The present disclosure provides a pharmaceutical composition comprising i) an A1 adenosine receptor (A1AR) agonist, ii) an A1AR antagonist, and iii) an anticholinergic. Kits utilizing i) an A1 adenosine receptor (A1AR) agonist, ii) an A1AR antagonist, and iii) an anticholinergic are also provided, as well as methods utilizing the described pharmaceutical compositions and kits. |
| FILED | Friday, March 11, 2022 |
| APPL NO | 17/692383 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7076 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911436 | Puttur et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Santhoshkumar Puttur (Columbia, Missouri); Krishna Sharma (Columbia, Missouri); Sundararajan Mahalingam (Columbia, Missouri) |
| ABSTRACT | The present disclosure provides amphiphilic peptide chaperones. Also provided are their incorporation into pharmaceutical compositions and methods of use for preventing or reducing a source of stress in cells and for the treatment of disorders including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis (ALS), cataract, age-related macular degeneration (AMD), glaucoma, and retinitis pigmentosa. |
| FILED | Thursday, June 02, 2022 |
| APPL NO | 17/830565 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/10 (20130101) Original (OR) Class A61K 47/542 (20170801) A61K 47/6929 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911441 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | ONCOIMMUNE, INC. (Rockville, Maryland); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | ONCOIMMUNE, INC. (Rockville, Maryland); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Yang Liu (Baltimore, Maryland); Pan Zheng (Baltimore, Maryland); Martin Devenport (Gaithersburg, Maryland) |
| ABSTRACT | The present invention relates to the use of a CD24 protein for preventing or treating relapse of a cancer in a subject. The present invention also relates to the use of a CD24 protein for reducing cancer stem cell activity. |
| FILED | Monday, June 03, 2019 |
| APPL NO | 15/734957 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/02 (20130101) A61K 38/177 (20130101) Original (OR) Class A61K 39/001129 (20180801) A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/04 (20180101) A61P 37/06 (20180101) Peptides C07K 14/70596 (20130101) C07K 16/4241 (20130101) C07K 2317/41 (20130101) C07K 2317/53 (20130101) C07K 2317/524 (20130101) C07K 2317/526 (20130101) C07K 2317/528 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911442 | Yang |
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| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Tianxin Yang (Salt Lake City, Utah) |
| ABSTRACT | Disclosed are methods of treating obesity or an obesity-related condition comprising administering an effective amount of soluble (pro)renin receptor (sPRR) to a subject that is obese or having an obesity-related condition. In some instances, obesity-related conditions can be, but are not limited to, steatosis, hyperglycemia, insulin resistance, chronic renal disease. Disclosed are methods of reducing body weight comprising administering an effective amount of sPRR to a subject in need thereof. Disclosed are methods of treating fatty liver in a subject comprising administering an effective amount of sPRR to a subject in need thereof. Disclosed are methods of treating a fluid and electrolyte disorder comprising administering an effective amount of sPRR to a subject diagnosed with a fluid and electrolyte disorder. |
| FILED | Thursday, December 22, 2022 |
| APPL NO | 18/145730 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/177 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911444 | Comer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Stratatech Corporation (Madison, Wisconsin) |
| ASSIGNEE(S) | Stratatech Corporation (Madison, Wisconsin) |
| INVENTOR(S) | Allen R. Comer (Madison, Wisconsin); B. Lynn Allen-Hoffmann (Madison, Wisconsin) |
| ABSTRACT | The present invention relates generally to compositions for treating patients that have skin cancer or have recently had skin cancers removed. More specifically, the present invention provides human skin substitutes engineered to express exogenous IL-12 and compositions and methods for making human skin substitutes engineered to express exogenous IL-12. In addition, the present invention provides methods for treatment of sites on a patient where skin cancers have been removed with human skin substitutes engineered to express exogenous IL-12. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/150048 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 38/208 (20130101) Original (OR) Class A61K 48/00 (20130101) Peptides C07K 14/5434 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0629 (20130101) C12N 2501/23 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911450 | Levitt et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| INVENTOR(S) | Roy Levitt (Miami, Florida); Gerald Z. Zhuang (Miami, Florida) |
| ABSTRACT | The invention provides a method of treating or preventing pain in a subject in need thereof. The method comprising administering to the subject an expression vector comprising a nucleic acid sequence encoding carbonic anhydrase (10) or carbonic anhydrase (11) such that the nucleic acid is expressed to produce carbonic anhydrase (10) or carbonic anhydrase (11). Alternatively, the method comprising administering to the subject an expression vector comprising a nucleic acid sequence encoding a carbonic anhydrase (8) fragment such that the nucleic acid is expressed to produce the carbonic anhydrase (8) fragment. |
| FILED | Friday, July 13, 2018 |
| APPL NO | 16/629477 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 38/51 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/02 (20180101) A61P 29/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 15/86 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 402/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911464 | Davis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Prommune, Inc. (Topeka, Kansas); Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Prommune, Inc. (Topeka, Kansas); Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Paul Davis (Omaha, Nebraska); Samer Al-Murrani (Overland Park, Kansas) |
| ABSTRACT | Anti-parasitic compounds and uses thereof. Compounds comprising a C-terminal peptide adjuvant conjugated to an N-terminal peptide antigen via a protease-cleavable linker, said peptide adjuvant comprising a peptide analog of C5a, wherein said peptide antigen comprises an antigenic epitope of a parasitic organism, such as T. gondii. Methods of therapeutic or prophylactic treatment of a parasitic infections. |
| FILED | Friday, September 13, 2019 |
| APPL NO | 17/275892 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/002 (20130101) A61K 39/005 (20130101) A61K 39/008 (20130101) A61K 39/012 (20130101) A61K 39/015 (20130101) A61K 39/018 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/627 (20130101) A61K 2039/6031 (20130101) A61K 2039/55516 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911472 | Bollyky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INIMMUNE CORPORATION (Missoula, Montana) |
| ASSIGNEE(S) | INIMMUNE CORPORATION (Missoula, Montana) |
| INVENTOR(S) | Paul L. Bollyky (Stanford, California); William Parks (Seattle, Washington); Patrick Secor (Seattle, Washington) |
| ABSTRACT | Described here is a method for reducing or preventing Pseudomonas aeruginosa biofilm formation in a human subject in need thereof, comprising administering to the human subject a first composition comprising (a) an antigen-binding polypeptide that binds Pf-family bacteriophage, or (b) a vaccine against Pf-family bacteriophage. Also described is an antigen-binding polypeptide that binds specifically to a CoaB protein of Pf-family bacteriophage or fragment thereof. |
| FILED | Thursday, October 08, 2020 |
| APPL NO | 17/066005 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/104 (20130101) A61K 45/06 (20130101) Original (OR) Class A61K 47/646 (20170801) A61K 2039/505 (20130101) Peptides C07K 16/08 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911487 | Bacallao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Bloomington, Indiana); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Robert Bacallao (Indianapolis, Indiana); Simon Atkinson (Carmel, Indiana); George Rhodes (Fishers, Indiana); Peter Corridon (Indianapolis, Indiana) |
| ABSTRACT | The present invention provides methods and materials useful delivering liquids, including liquids comprising nucleic acid molecules into cells. In particular, the present invention provides methods for delivering saline solution, exogenous compositions, and isolated vectors to kidney cells, using the renal vein as a guide and under hydrodynamic pressure. The delivery methods and materials herein are useful to research, prognose, ameliorate symptoms of kidney injury, and treat kidney pathologies. |
| FILED | Friday, May 03, 2013 |
| APPL NO | 14/398697 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/45 (20130101) A61K 38/443 (20130101) A61K 48/0058 (20130101) A61K 48/0075 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10041 (20130101) Enzymes C12Y 101/01042 (20130101) C12Y 208/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911488 | Pomper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSTY (Baltimore, Maryland) |
| INVENTOR(S) | Martin G. Pomper (Baltimore, Maryland); Ronnie C. Mease (Fairfax, Virginia); Sangeeta Ray (Ellicott City, Maryland); Ying Chen (Lutherville-Timonium, Maryland); Xing Yang (Balitmore, Maryland) |
| ABSTRACT | Carbamate and beta-amino acid urea-based scaffolds that have high binding affinity to PSMA are disclosed. These scaffolds can be radiolabeled and used for imaging cells and tumors that express PSMA or for cancer radiotherapy. These compounds also can comprise a fluorescent dye and be used for imaging cells and tumors that express PSMA or for photodynamic therapy. |
| FILED | Tuesday, August 04, 2020 |
| APPL NO | 16/984415 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0057 (20130101) A61K 49/0002 (20130101) A61K 49/0017 (20130101) A61K 49/0019 (20130101) A61K 49/0021 (20130101) A61K 49/0032 (20130101) A61K 49/0041 (20130101) A61K 49/0052 (20130101) A61K 51/0402 (20130101) Original (OR) Class A61K 51/0455 (20130101) Acyclic or Carbocyclic Compounds C07C 271/22 (20130101) C07C 275/16 (20130101) C07C 323/62 (20130101) Heterocyclic Compounds C07D 209/12 (20130101) C07D 213/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911566 | Zapol et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Third Pole, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Third Pole, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | David G. Zapol (San Francisco, California); Gregory W. Hall (Belmont, Massachusetts); Wolfgang Scholz (Beverly, Massachusetts); Benjamin Apollonio (Lunenburg, Massachusetts); Frank Heirtzler (Londonderry, New Hampshire); Andrew Ferencz (Southborough, Massachusetts) |
| ABSTRACT | Systems and methods are provided for portable and compact nitric oxide (NO) generation that can be embedded into other therapeutic devices or used alone. In some embodiments, an ambulatory NO generation system can be comprised of a controller and disposable cartridge. The cartridge can contain filters and scavengers for preparing the gas used for NO generation and for scrubbing output gases prior to patient inhalation. The system can utilize an oxygen concentrator to increase nitric oxide production and compliment oxygen generator activity as an independent device. The system can also include a high voltage electrode assembly that is easily assembled and installed. Various nitric oxide delivery methods are provided, including the use of a nasal cannula. |
| FILED | Tuesday, December 13, 2022 |
| APPL NO | 18/065337 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/04 (20130101) A61M 16/12 (20130101) Original (OR) Class A61M 16/022 (20170801) A61M 16/024 (20170801) A61M 16/0057 (20130101) A61M 16/0093 (20140204) A61M 16/101 (20140204) A61M 16/107 (20140204) A61M 16/202 (20140204) A61M 16/0666 (20130101) A61M 2202/0275 (20130101) A61M 2202/0283 (20130101) A61M 2205/05 (20130101) A61M 2205/054 (20130101) A61M 2205/80 (20130101) A61M 2205/125 (20130101) A61M 2205/502 (20130101) A61M 2205/3584 (20130101) A61M 2205/8206 (20130101) A61M 2209/088 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911609 | Heldman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Great Lakes NeuroTechnologies Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | Great Lakes NeuroTechnologies Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Dustin A Heldman (Shaker Heights, Ohio); Joseph P Giuffrida (Hinckley, Ohio) |
| ABSTRACT | The present invention relates to a system and methods for noninvasively providing therapy for movement disorder symptoms. The present invention provides such a therapy system which provides trans-cranial direct current stimulation (tDCS) in order to treat those symptoms and the disorders. The present invention further provides such tDCS therapy while the subject sleeps in order to minimize the time required and impact of the therapy on the subject's waking life. The system, methods, and devices of the present invention are intended to provide a low-dose electrical current, trans-cranially, to a specific area of the subject's brain while he or she sleeps in order to decrease the occurrence, severity, and duration of the symptoms of movement disorders. The present invention aims to reduce the amount of medication necessary, counteract the effects of medication wearing off during sleep, and to overall improve the quality of life of subjects suffering from movement disorders. |
| FILED | Wednesday, April 07, 2021 |
| APPL NO | 17/224263 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/20 (20130101) Original (OR) Class A61N 1/0492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911611 | Jaroszeski et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida); Douglas Walter Brown (Northumberland, Pennsylvania) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Mark Jeffrey Jaroszeski (Wesley Chapel, Florida); Timothy Fawcett (Seffner, Florida); Richard Jason Connolly (Riverview, Florida); Andrew M. Hoff (Tampa, Florida); Reginald Morley Atkins (Riverview, Florida); Douglas Walter Brown (Sunbury, Pennsylvania); Richard A. Gilbert (Tampa, Florida) |
| ABSTRACT | The present invention provides a system and method for measuring an impedance of one or more target cells before and after an electroporation protocol has been applied to the one or more target cells. The result of the impedance measurement provides a feedback control that can be implemented during and/or after the electroporation protocol to customize the electrical treatment for a particular target cell or cellular tissue. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734551 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/326 (20130101) Original (OR) Class A61N 1/327 (20130101) Apparatus for Enzymology or Microbiology; C12M 35/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911651 | Adams et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Barron Associates, Inc. (Charlottesville, Virginia) |
| ASSIGNEE(S) | Barron Associates, Inc. (Charlottesville, Virginia) |
| INVENTOR(S) | Richard J. Adams (Punta Gorda, Florida); William T. Gressick (Charlottesville, Virginia); Aaron B. Olowin (Charlottesville, Virginia); Matthew Lichter (Charlottesville, Virginia) |
| ABSTRACT | Embodiments of the presently described device, system and method support upper extremity therapy through a control device. In various embodiments, the control device is provided as a central hub with atomic elements extending outwardly thereof, and the control device can incorporate a movement interpretation circuit, a touch detection circuit and/or one or more sensory transducers. In various embodiments, the control device is interoperable with a valence, an external computing device and a display device. Embodiments of the external computing device are operable to render a graphical depiction of simulated objects in a virtual world upon receiving a transmission of sensed human grasping of one or more atomic elements. |
| FILED | Thursday, August 10, 2023 |
| APPL NO | 18/232581 |
| ART UNIT | 2626 — Selective Visual Display Systems |
| CURRENT CPC | Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment A63B 22/0005 (20151001) Original (OR) Class A63B 24/0062 (20130101) A63B 71/0622 (20130101) A63B 2022/0094 (20130101) A63B 2024/0096 (20130101) A63B 2071/0638 (20130101) A63B 2071/0655 (20130101) A63B 2220/58 (20130101) A63B 2220/833 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/016 (20130101) G06F 3/041 (20130101) G06F 3/0346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911763 | Brouzes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Eric Brouzes (Port Jefferson, New York); Martin Sauzade (Setauket, New York) |
| ABSTRACT | This disclosure provides devices and methods for the isolation of single cells or particles of interest from a solution comprising a plurality of cells or a solution composed of a homogenous population of particles. Specifically, the present disclosure is directed to microfluidic devices and methods for analyzing cells in a sample. More specifically, the present disclosure provides droplet microfluidic devices and methods for using the same to obtain (trap), encapsulate, and retrieve (isolate) single cells or particles from a sample with improved efficiency. |
| FILED | Thursday, November 04, 2021 |
| APPL NO | 17/518684 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 3/502784 (20130101) B01L 2200/0668 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2400/0487 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911999 | Singamaneni et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Srikanth Singamaneni (St. Louis, Missouri); Jingyi Luan (St. Louis, Missouri); Jeremiah Morrissey (St. Louis, Missouri); Evan Kharasch (St. Louis, Missouri) |
| ABSTRACT | Fluorescence-based techniques are the cornerstone of modern biomedical optics with applications ranging from bioimaging at various scales (organelle to organism) to detection and quantification of a wide variety of biological species of interest. However, feeble fluorescence signal remains a persistent challenge in meeting the ever-increasing demand to image, detect and quantify biological species of low abundance. Disclosed herein are simple and universal methods based on a flexible and conformal elastomeric film adsorbed with plasmonic nanostructures, referred to as “plasmonic skin” or “plasmonic patch”, that provide large and uniform enhancement of fluorescence on a variety of surfaces, through an “add-on-top” process. The novel fluorescence enhancement approach presented here represents a disease-, biomarker-, and application-agnostic ubiquitously-applicable fundamental and enabling technology to improve the sensitivity of existing analytical methodologies in an easy-to-handle and cost-effective manner, without changing and/or minimally altering the original procedures of the existing techniques. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/662293 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/06 (20130101) Original (OR) Class B32B 2307/422 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912659 | Messick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Troy E. Messick (Upper Darby, Pennsylvania); Garry R. Smith (King of Prussia, Pennsylvania); Allen B. Reitz (Lansdale, Pennsylvania); Paul M. Lieberman (Wynnewood, Pennsylvania); Mark E. McDonnell (Lansdale, Pennsylvania); Yan Zhang (Fort Washington, Pennsylvania); Marianne Carlsen (Yardley, Pennsylvania); Shuai Chen (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by EBNA1 activity, such as, but not limited to, cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and/or rheumatoid arthritis. The present invention further provides EBNA1 inhibitors, and/or pharmaceutical compositions comprising the same, that are useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection and/or lytic EBV infection. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/232511 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/41 (20130101) A61K 31/404 (20130101) A61K 31/422 (20130101) A61K 31/426 (20130101) A61K 31/427 (20130101) A61K 31/433 (20130101) A61K 31/435 (20130101) A61K 31/437 (20130101) A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/501 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/541 (20130101) A61K 31/551 (20130101) A61K 31/4155 (20130101) A61K 31/4375 (20130101) A61K 31/4439 (20130101) A61K 31/4725 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 209/08 (20130101) Original (OR) Class C07D 277/62 (20130101) C07D 401/10 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/10 (20130101) C07D 403/12 (20130101) C07D 403/14 (20130101) C07D 405/12 (20130101) C07D 405/14 (20130101) C07D 409/12 (20130101) C07D 413/10 (20130101) C07D 417/10 (20130101) C07D 417/12 (20130101) C07D 471/04 (20130101) C07D 471/08 (20130101) C07D 471/10 (20130101) C07D 487/04 (20130101) C07D 487/08 (20130101) C07D 491/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912660 | Sridhar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xavier University of Louisiana (New Orleans, Louisiana) |
| ASSIGNEE(S) | Xavier University of Louisiana (New Orleans, Louisiana) |
| INVENTOR(S) | Jayalakshmi Sridhar (New Orleans, Louisiana); Melyssa Bratton (New Orleans, Louisiana); Rajesh Komati (Thibodaux, Louisiana) |
| ABSTRACT | The present disclosure relates to compounds that act as protein kinase inhibitors, especially RPS6K1 and the synthesis of the same. Further, the present disclosure teaches the utilization of such compounds in a treatment for proliferative diseases, including cancer, particularly breast cancer, and especially ER+ and/or HER2+ breast cancer, prostate cancer, lung cancer, and metastatic cancer. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/232469 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 209/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912687 | Witt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of the Southern Illinois University (Edwardsville, Illinois) |
| ASSIGNEE(S) | Board of Trustees of the Southern Illinois University (Edwardsville, Illinois) |
| INVENTOR(S) | Kenneth A. Witt (Edwardsville, Illinois); Albert M. Crider (Maryville, Illinois); William Neumann (St. Louis, Missouri); Audrey Hospital (Robbinsville, New Jersey); Karin Sandoval (Edwardsville, Illinois); Maria Kontoyianni (Glen Carbon, Illinois) |
| ABSTRACT | The present disclosure describes novel compounds that are somatostatin receptor type 4 agonists. The present disclosure is also directed to a compound of Formula (II): |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/466480 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/06 (20130101) C07D 403/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912702 | Fuller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alkermes, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Alkermes, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Nathan Oliver Fuller (Arlington, Massachusetts); John A. Lowe, III (Stonington, Connecticut) |
| ABSTRACT | Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g,. HDAC2). |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 17/558840 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 487/04 (20130101) C07D 513/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912709 | Emrick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Todd Emrick (South Deerfield, Massachusetts); Matthew Skinner (Amherst, Massachusetts); Sarah M. Ward (Amherst, Massachusetts); Banishree Saha (Greenfield, Massachusetts) |
| ABSTRACT | A temozolomide compound according to formula (I) is described, wherein R1, L1, and X are defined herein. The temozolomide compound can be used to prepare polymers comprising temozolomide. Additionally, the polymers comprising temozolomide can be particularly useful in the treatment of certain diseases. |
| FILED | Monday, March 01, 2021 |
| APPL NO | 17/188162 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/787 (20130101) A61K 47/58 (20170801) A61K 47/60 (20170801) A61K 47/545 (20170801) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 22/10 (20130101) C08F 220/365 (20200201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912713 | Speerschneider et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trevena, Inc. (Chesterbrook, Pennsylvania) |
| ASSIGNEE(S) | Trevena, Inc. (Chesterbrook, Pennsylvania) |
| INVENTOR(S) | Aimee Crombie Speerschneider (Chesterbrook, Pennsylvania); Dennis Shinji Yamashita (Chesterbrook, Pennsylvania); Philip Michael Pitis (Chesterbrook, Pennsylvania); Michael John Hawkins (Chesterbrook, Pennsylvania); Guodong Liu (Chesterbrook, Pennsylvania); Tamara Ann Miskowski Daubert (Chesterbrook, Pennsylvania); Catherine C. K. Yuan (Chesterbrook, Pennsylvania); Robert Borbo Kargbo (Chesterbrook, Pennsylvania); Robert Jason Herr (Chesterbrook, Pennsylvania); Donna Romero (Chesterbrook, Pennsylvania) |
| ABSTRACT | The present embodiments are directed, in part, to compounds, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof for modulating the activity of delta opioid receptor, biased and/or unbiased, and/or methods for treating pain, migraines, headaches, depression, Parkinsons Disease, anxiety, and/or overactive bladder, and other disorders and conditions described herein or any combination thereof. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/532413 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 23/00 (20180101) A61P 25/22 (20180101) A61P 25/24 (20180101) Heterocyclic Compounds C07D 223/04 (20130101) C07D 403/12 (20130101) C07D 403/14 (20130101) C07D 405/14 (20130101) C07D 417/14 (20130101) C07D 487/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912734 | Greenberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Marc M. Greenberg (Baltimore, Maryland); Haozhe Yang (Baltimore, Maryland) |
| ABSTRACT | A strategy using reverse phosphoramidites for synthesizing oligonucleotides containing Fapy·dG is disclosed. |
| FILED | Thursday, January 28, 2021 |
| APPL NO | 17/161272 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) Original (OR) Class C07H 19/06 (20130101) C07H 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912736 | Burkhart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF MONTANA (Missoula, Montana) |
| ASSIGNEE(S) | THE UNIVERSITY OF MONTANA (Missoula, Montana) |
| INVENTOR(S) | David Burkhart (Missoula, Montana); George Ettenger (Missoula, Montana); Jay Evans (Corvallis, Montana); Kendal T. Ryter (Hamilton, Montana); Alyson Smith (Bonner, Montana) |
| ABSTRACT | Disclosed herein are diaryl trehalose compounds and methods of use thereof, for example as vaccine adjuvants. |
| FILED | Thursday, February 21, 2019 |
| APPL NO | 16/968075 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 39/39 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 13/08 (20130101) Original (OR) Class C07H 15/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912742 | Crawford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Jason Crawford (Shelton, Connecticut); Jhe-Hao Li (New Haven, Connecticut); Joonseok Oh (West Haven, Connecticut) |
| ABSTRACT | The present disclosure includes a construct comprising a leupeptin biosynthesis operon, the operon comprising leupA, leupB, leupC, and leupD genes operably linked to a promoter. Also included are cells comprising the construct, and methods for production of leupeptin peptide. |
| FILED | Wednesday, June 30, 2021 |
| APPL NO | 17/363433 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/195 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912744 | Herzberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Antibiotic Alternatives LLC (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Antibiotic Alternatives LLC (Minneapolis, Minnesota) |
| INVENTOR(S) | Mark C. Herzberg (Minneapolis, Minnesota); Karen Farnie Ross (St. Paul, Minnesota); Brent S. Sorenson (Minneapolis, Minnesota) |
| ABSTRACT | This disclosure describes compositions and methods involved in tumor suppression and inhibiting infection of cells by pathogens. Generally, the compositions include an mRNA cargo that can provide a therapeutic benefit after being introduced into an epithelial cell. In some cases, the mRNA can encode a polypeptide. In some cases, the polypeptide can suppress epithelial cell proliferation. In other embodiments, the polypeptide can be involved in innate immunity. In various embodiments, the polypeptide can include cathelicin antimicrobial protein (CAMP), calprotectin, S100A8, S100A9, a β-defensin, S100A7, secretory leukocyte inhibitor, lipocalin 2, or lysozyme. In some embodiments, the mRNA can include a stabilizing moiety such as, for example, a 5′ cap or a 3′ extension. |
| FILED | Tuesday, April 07, 2020 |
| APPL NO | 16/842489 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 48/005 (20130101) Peptides C07K 14/47 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 2840/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912753 | Scholler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Nathalie Scholler (Narberth, Pennsylvania); Katarzyna Urbanska (Philadelphia, Pennsylvania); Daniel J. Powell, Jr. (Bala Cynwyd, Pennsylvania) |
| ABSTRACT | The invention provides compositions and methods for adoptive T cell therapy in treating a variety of disorders including cancer, infections, and autoimmune disorders. In one embodiment, the invention provides a universal immune receptor (UnivIR) that comprises an extracellular label binding domain, a transmembrane domain, and a cytoplasmic domain or otherwise an intracellular domain. |
| FILED | Monday, June 21, 2021 |
| APPL NO | 17/353414 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6851 (20170801) Peptides C07K 14/465 (20130101) C07K 14/7051 (20130101) Original (OR) Class C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) C07K 2319/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912772 | Ndhlovu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Hawaii (Honolulu, Hawaii) |
| ASSIGNEE(S) | University of Hawaii (Honolulu, Hawaii) |
| INVENTOR(S) | Lishomwa C. Ndhlovu (Honolulu, Hawaii); Toshiro Niki (Honolulu, Hawaii) |
| ABSTRACT | An antibody targeting Galectin-9 is provided as are methods of using the same treatment of chronic immune conditions such as infections, inflammatory diseases and cancer, in particular malignant mesothelioma. |
| FILED | Friday, July 12, 2019 |
| APPL NO | 17/260077 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2851 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912786 | Cosford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Nicholas David Peter Cosford (San Diego, California); Mitchell Dennis Vamos (San Diego, California) |
| ABSTRACT | Provided herein are compounds that modulate the activity of inhibitor of apoptosis proteins (IAPs), compositions comprising the compounds, and methods of using the compounds and compositions comprising the compounds. |
| FILED | Thursday, July 29, 2021 |
| APPL NO | 17/389171 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Heterocyclic Compounds C07D 487/04 (20130101) C07D 487/14 (20130101) C07D 498/04 (20130101) C07D 498/10 (20130101) C07D 513/04 (20130101) Peptides C07K 5/0806 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912985 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Andrew Vito Anzalone (Cambridge, Massachusetts); Jonathan Ma Levy (Cambridge, Massachusetts); Xin Gao (Cambridge, Massachusetts); Christopher J. Podracky (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides systems, compositions, and methods for simultaneously editing both strands of a double-stranded DNA sequence at a target site to be edited. Further provided herein are pharmaceutical compositions, polynucleotides, vectors, cells, and kits for simultaneously editing both strands of a double-stranded DNA sequence. |
| FILED | Monday, November 07, 2022 |
| APPL NO | 18/053269 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/1276 (20130101) C12N 15/102 (20130101) Original (OR) Class C12N 15/111 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912986 | Mali et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Prashant Mali (La Jolla, California); Udit Parekh (La Jolla, California); Yan Wu (La Jolla, California); Kun Zhang (La Jolla, California) |
| ABSTRACT | Understanding the complex effects of genetic perturbations on cellular state and fitness in human pluripotent stem cells (hPSCs) has been challenging using traditional pooled screening techniques which typically rely on unidimensional phenotypic readouts. Here, Applicants use barcoded open reading frame (ORF) overexpression libraries with a coupled single-cell RNA sequencing (scRNA-seq) and fitness screening approach, a technique we call SEUSS (ScalablE fUnctional Screening by Sequencing), to establish a comprehensive assaying platform. Using this system, Applicants perturbed hPSCs with a library of developmentally critical transcription factors (TFs), and assayed the impact of TF overexpression on fitness and transcriptomic cell state across multiple media conditions. Applicants further leveraged the versatility of the ORF library approach to systematically assay mutant gene libraries and also whole gene families. From the transcriptomic responses, Applicants built genetic co-perturbation networks to identify key altered gene modules. Strikingly, we found that KLF4 and SNAI2 have opposing effects on the pluripotency gene module, highlighting the power of this method to characterize the effects of genetic perturbations. From the fitness responses, Applicants identified ETV2 as a driver of reprogramming towards an endothelial-like state. |
| FILED | Tuesday, September 22, 2020 |
| APPL NO | 17/028836 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 15/86 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 2506/45 (20130101) C12N 2740/15043 (20130101) C12N 2740/15052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912994 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jeannie T. Lee (Boston, Massachusetts); Anand Minajigi (Boston, Massachusetts); Lieselot Carrette (Beernem, Belgium) |
| ABSTRACT | Methods for reactivating genes on the inactive X chromosome that include administering one or both of a DNA methyltransferase (DNMT) Inhibitor and/or a topoisomerase inhibitor, e.g., etoposide and/or 5′-azacytidine (aza), optionally in combination with an inhibitor of XIST RNA and/or an Xist-interacting protein, e.g., a chromatin-modifying protein, e.g., a small molecule or an inhibitory nucleic acid (such as a small inhibitory RNA (siRNAs) or antisense oligonucleotide (ASO)) that targets XIST RNA and/or a gene encoding an Xist-interacting protein, e.g., a chromatin-modifying protein. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/214320 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/90 (20130101) C12N 9/1007 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2310/113 (20130101) C12N 2310/531 (20130101) C12N 2310/531 (20130101) C12N 2310/3231 (20130101) C12N 2320/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 201/01037 (20130101) C12Y 599/01002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912995 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | Hua Yu (Glendora, California); Andreas Herrmann (La Jolla, California); Marcin Tomasz Kortylewski (Monrovia, California); Piotr Marek Swiderski (San Dimas, California) |
| ABSTRACT | Provided herein are, inter alia, nucleic acid compounds useful for targeting CTLA-4-expressing cells and modulating cell activity of the CTLA-4-expressing cells. The compositions provided herein may be part of pharmaceutical compositions and may be used for treatment of cancer, inflammatory diseases, infectious diseases or metabolic diseases. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/452172 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 45/06 (20130101) A61K 47/549 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/115 (20130101) C12N 15/1138 (20130101) C12N 2310/11 (20130101) C12N 2310/12 (20130101) C12N 2310/13 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/3519 (20130101) C12N 2320/30 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912998 | Wyss-Coray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Anton Wyss-Coray (Palo Alto, California); Thomas A. Rando (Stanford, California); Markus Britschgi (Allscwil, Switzerland); Kaspar Rufibach (Basel, Switzerland); Saul A. Villeda (Lancaster, California) |
| ABSTRACT | Methods of treating an adult mammal for an aging-associated impairment are provided. Aspects of the methods include modulating CCR3, e.g., by modulating eotaxin-1/CCR3 interaction, in the mammal in a manner sufficient to treat the mammal for the aging-associated impairment. A variety of aging-associated impairments may be treated by practice of the methods, which impairments include cognitive impairments. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/550787 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/7088 (20130101) A61K 38/19 (20130101) A61K 38/45 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/24 (20130101) C07K 16/28 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2799/06 (20130101) C12N 2799/022 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 207/10001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913013 | Sullivan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland); Sabin Vaccine Institute (Washington, District of Columbia) |
| ASSIGNEE(S) | SABIN VACCINE INSTITUTE (Washington, District of Columbia) |
| INVENTOR(S) | Nancy J. Sullivan (Kensington, Maryland); Gary J. Nabel (Washington, District of Columbia); Clement Asiedu (Olney, Maryland); Cheng Cheng (Rockville, Maryland); Alfredo Nicosia (Rome, Italy); Riccardo Cortese (Rome, Italy); Virginia Ammendola (Naples, Italy); Stefano Colloca (Rome, Italy) |
| ABSTRACT | This invention provides vaccines for inducing an immune response and protection against filovirus infection for use as a preventative vaccine in humans. In particular, the invention provides chimpanzee adenoviral vectors expressing filovirus proteins from different strains of Ebolavirus (EBOV) or Marburg virus (MARV). |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/389421 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/545 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) C07K 14/08 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 15/861 (20130101) C12N 15/8636 (20130101) C12N 2710/10341 (20130101) C12N 2710/10343 (20130101) C12N 2710/24111 (20130101) C12N 2710/24141 (20130101) C12N 2760/14111 (20130101) C12N 2760/14134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913017 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kun Zhang (La Jolla, California); Prashant Mali (La Jolla, California); Yan Wu (La Jolla, California); Dongxin Zhao (La Jolla, California) |
| ABSTRACT | A guide RNA comprising: a gRNA spacer sequence at the 5′ end of the guide RNA, wherein the spacer sequence is complementary to a target gene, a scaffold sequence that binds to Cas9, and an RNA capture and sequencing domain comprising: a barcode sequence, and a primer binding sequence; nucleic acids and vectors encoding the guide RNA; cells expressing the guide RNA; and a library comprising a plurality of guide RNAs. Also disclosed are methods of introducing a genetic perturbation into a cell, methods of assessing an effect of at least one genetic perturbation on RNA expression in a cell, methods of identifying nucleic acid sequences associated with a disease state and a method of identifying candidate therapeutic agents. |
| FILED | Wednesday, June 28, 2017 |
| APPL NO | 16/312907 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/102 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2320/12 (20130101) C12N 2330/31 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/20 (20190201) G16B 25/10 (20190201) G16B 40/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913021 | Rafii et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell Research Foundation, Inc. (Ithaca, New York); Sloan-Kettering Institute for Cancer Research (New York, New York) |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York); Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Shahin Rafii (New York, New York); Fan Zhang (Fort Lee, New Jersey); Marco Seandel (New York, New York) |
| ABSTRACT | The present invention relates to adenovirus E4ORF1 gene and to endothelial cells engineered to express the E4ORF1 gene. The present invention also relates to uses of the E4ORF1 gene, and cells expressing the E4ORF1 gene, and to compositions comprising the E4ORF1 gene, or comprising cells expressing the E4ORF1 gene. |
| FILED | Monday, November 16, 2020 |
| APPL NO | 17/099122 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) C12N 5/0606 (20130101) Original (OR) Class C12N 5/0647 (20130101) C12N 5/0693 (20130101) C12N 15/1131 (20130101) C12N 15/1136 (20130101) C12N 2310/14 (20130101) C12N 2501/998 (20130101) C12N 2710/10322 (20130101) C12N 2740/10043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913026 | Tsourkas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Andrew Tsourkas (Bryn Mawr, Pennsylvania); James Z. Hui (Philadelphia, Pennsylvania); Burcin Altun (Philadelphia, Pennsylvania); Fabiana Zappala (Philadelphia, Pennsylvania) |
| ABSTRACT | A bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody comprising a cytotoxic lymphocyte or macrophage targeting domain and an autoantibody. Methods for producing bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody comprising a cytotoxic lymphocyte or macrophage targeting domain and an autoantibody. Methods for treating a subject in need thereof comprising administering to the subject an isolated bispecific cytotoxic lymphocyte or macrophage-redirecting autoantibody. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 16/821933 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2809 (20130101) C07K 16/2827 (20130101) C07K 16/3015 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) Original (OR) Class C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913028 | Eguchi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Asuka Eguchi (Menlo Park, California); Aseem Z. Ansari (Germantown, Tennessee) |
| ABSTRACT | The present invention relates to artificial transcription factors (ATFs) that alter gene expression, including inducing pluripotency in cells or promoting the conversion of cells to specific cell fates. In particular, provided herein is a zinc-finger based ATF library that can be screened in cells by looking for expression of a specific gene (e.g., reporter expression), monitoring for cell surface markers or morphology, or via functional assays. |
| FILED | Wednesday, June 16, 2021 |
| APPL NO | 17/349243 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 1/047 (20130101) C07K 14/4702 (20130101) C07K 2319/09 (20130101) C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 5/0657 (20130101) C12N 5/0696 (20130101) Original (OR) Class C12N 2500/25 (20130101) C12N 2501/40 (20130101) C12N 2501/60 (20130101) C12N 2501/115 (20130101) C12N 2501/145 (20130101) C12N 2501/415 (20130101) C12N 2501/602 (20130101) C12N 2501/604 (20130101) C12N 2501/606 (20130101) C12N 2501/727 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913044 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Tina Wang (Cambridge, Massachusetts) |
| ABSTRACT | Some aspects of this disclosure relate to strategies, systems, methods, compositions, and kits that are useful for production (e.g., evolution) of cytidine deaminase protein variants that are characterized by increased soluble expression and/or stability relative to the wild-type cytidine deaminase protein from which they are evolved. In some embodiments, evolved cytidine deaminase variants described by the disclosure are useful for incorporation into targeted nucleic acid editing proteins, for example in fusion proteins with a Cas9 domain or variant thereof. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 17/251276 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/78 (20130101) Original (OR) Class Enzymes C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913068 | Bram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Asuragen, Inc. (Austin, Texas) |
| ASSIGNEE(S) | Asuragen, Inc. (Austin, Texas) |
| INVENTOR(S) | Eran Bram (Cedar Park, Texas); Raghav Shroff (Austin, Texas); Andrew Hadd (Austin, Texas); Blake Printy (Austin, Texas) |
| ABSTRACT | Disclosed herein are data processing and calculating annotation systems and devices, and corresponding methods, for nucleic acid analysis. In particular, disclosed herein are methods for sizing a repeat region of a nucleic acid sample. For example, the methods disclosed herein use a ladder of amplification products to determine nucleic acid size. |
| FILED | Friday, August 23, 2019 |
| APPL NO | 16/549684 |
| ART UNIT | 1672 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6858 (20130101) Original (OR) Class C12Q 1/6858 (20130101) C12Q 2525/151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913070 | Lindsay |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Stuart Lindsay (Scottsdale, Arizona) |
| ABSTRACT | The present disclosure provides devices, systems, and methods related to sequencing a biopolymer. In particular, the present disclosure provides methods of obtaining a bioelectronic signature based on current fluctuations that correspond to the activity of an enzyme-of-interest. As described herein, certain aspects of the bioelectronic signature can be used to determine the sequence of a biopolymer. |
| FILED | Wednesday, February 24, 2021 |
| APPL NO | 17/184201 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/005 (20130101) C12Q 1/6869 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/125 (20130101) G01N 33/48721 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/20 (20190201) G16B 40/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913075 | Regev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Orit Rozenblatt-Rosen (Cambridge, Massachusetts); Benjamin Izar (Boston, Massachusetts); Livnat Jerby (Cambridge, Massachusetts); Asaf Rotem (Boston, Massachusetts) |
| ABSTRACT | The subject matter disclosed herein is generally directed to detecting and modulating novel gene signatures for the treatment and prognosis of cancer. The novel gene signatures predict overall survival in cancer and can be targeted therapeutically. |
| FILED | Friday, March 30, 2018 |
| APPL NO | 16/499908 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913076 | Srivastava et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| ASSIGNEE(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| INVENTOR(S) | Shiv K. Srivastava (Potomac, Maryland); Gyorgy Petrovics (Bethesda, Maryland); Indu Kohaar (North Potomac, Maryland) |
| ABSTRACT | The present disclosure provides gene expression profiles that are associated with prostate cancer, including certain gene expression profiles that differentiate between subjects of African and Caucasian descent and other gene expression profiles that are common to subjects of both African and Caucasian descent. The gene expression profiles can be measured at the nucleic acid or protein level and used to stratify prostate cancer based on ethnicity. The gene expression profiles can also be used to identify a subject for prostate cancer treatment. Also provided are kits for diagnosing and prognosing prostate cancer and an array comprising probes for detecting the unique gene expression profiles associated with prostate cancer in subjects of African and/or Caucasian descent. |
| FILED | Tuesday, May 08, 2018 |
| APPL NO | 16/611692 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) G16B 25/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913081 | Dickinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Bryan C. Dickinson (Chicago, Illinois); Jinyue Pu (Chicago, Illinois); Julia Zinkus (Chicago, Illinois) |
| ABSTRACT | A proximity dependent split T7 RNAP (RNA polymerase) sensor using continuous molecular evolution is described. The versatility of the platform is described by creating robust light and small molecule-responsive genetic sensors. The activity-responsive RNAP platform dramatically simplifies and expands genetic circuit creation, and opens new opportunities in protein engineering, synthetic biology, and bioengineering. |
| FILED | Tuesday, June 06, 2017 |
| APPL NO | 16/305298 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1247 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) C12Q 1/689 (20130101) C12Q 1/6897 (20130101) Original (OR) Class Enzymes C12Y 207/07006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913722 | Andrews et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Robert R. Andrews (Norfolk, Massachusetts); Herman E. Snyder (W. Lafayette, Indiana); William J. Merritt (Danvers, Massachusetts); Evan P. Ordway (Salem, Massachusetts); Clair Strohl (Emmaus, Pennsylvania); Russell Barron (Boston, Massachusetts) |
| ABSTRACT | The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port. |
| FILED | Friday, January 13, 2023 |
| APPL NO | 18/096645 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/16 (20130101) Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 3/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913723 | Andrews et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Robert R. Andrews (Norfolk, Massachusetts); Herman E. Snyder (W. Lafayette, Indiana); William J. Merritt (Danvers, Massachusetts); Evan P. Ordway (Salem, Massachusetts); Clair Strohl (Emmaus, Pennsylvania); Russell Barron (Boston, Massachusetts) |
| ABSTRACT | The present invention includes a spray drying disposable device for use in a spray drying system. The disposable has a spray drying head and a plasma drying chamber. The head has a spray dry nozzle assembly in fluid communication with the plasma source and the pressurized aerosol gas source. The pressurized gas flows in a vortex pattern that atomizes plasma droplets in the chamber. The head also includes a plenum has uniform air pressure of the drying gas. A baffle plate forms the floor of the plenum having drying gas jets that supply drying gas to the chamber. The atomized plasma droplets evaporate in the presence of the drying gas emitted from the jets to obtain dried plasma particles and humid air. A capture filter captures the dried plasma particles and allows the humid air to pass. The humid air passes through the gas outlet and the exhaust port. |
| FILED | Friday, January 13, 2023 |
| APPL NO | 18/096945 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/16 (20130101) Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 3/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913872 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Darren Yang (Cambridge, Massachusetts); Andrew Ward (Boston, Massachusetts); Wesley Philip Wong (Cambridge, Massachusetts); Kenneth Anders Halvorsen (Glenmont, New York) |
| ABSTRACT | An apparatus for measuring a characteristic of a sample using a centrifuge and optical components is disclosed. The centrifuge may be a standard benchtop centrifuge. The optical components may be sized and dimensioned to fit, along with the sample, inside the centrifuge. |
| FILED | Thursday, February 04, 2021 |
| APPL NO | 17/167847 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Centrifuges B04B 13/00 (20130101) B04B 15/02 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/68 (20130101) C12Q 1/6816 (20130101) C12Q 2523/303 (20130101) C12Q 2525/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) G01N 21/07 (20130101) Original (OR) Class G01N 33/53 (20130101) G01N 33/543 (20130101) G01N 33/557 (20130101) G01N 2015/0038 (20130101) G01N 2015/0065 (20130101) G01N 2015/1006 (20130101) G01N 2201/021 (20130101) G01N 2201/0423 (20130101) G01N 2201/0693 (20130101) G01N 2203/0089 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913905 | Gundlach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Jens H. Gundlach (Seattle, Washington); Ian M. Derrington (Seattle, Washington); Marcus D. Collins (Issaquah, Washington) |
| ABSTRACT | Provided herein are methods and systems pertaining to sequencing units of analytes using nanopores. In general, arresting constructs are used to modify an analyte such that the modified analyte pauses in the opening of a nanopore. During such a pause, an ion current level is obtained that corresponds to a unit of the analyte. After altering the modified analyte such that the modified analyte advances through the opening, another arresting construct again pauses the analyte, allowing for a second ion current level to be obtained that represents a second unit of the analyte. This process may be repeated until each unit of the analyte is sequenced. Systems for performing such methods are also disclosed. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 17/534869 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Separation B01D 69/06 (20130101) B01D 2325/02 (20130101) B01D 2325/24 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 15/00 (20130101) Peptides C07K 14/35 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) G01N 27/44704 (20130101) G01N 27/44726 (20130101) G01N 27/44747 (20130101) G01N 27/44786 (20130101) G01N 27/44791 (20130101) Original (OR) Class G01N 33/48721 (20130101) Electric Digital Data Processing G06F 1/206 (20130101) G06F 3/061 (20130101) G06F 3/0604 (20130101) G06F 3/0614 (20130101) G06F 3/0616 (20130101) G06F 3/0625 (20130101) G06F 3/0629 (20130101) G06F 3/0647 (20130101) G06F 3/0653 (20130101) G06F 3/0659 (20130101) G06F 3/0673 (20130101) G06F 3/0679 (20130101) G06F 12/0238 (20130101) G06F 12/0246 (20130101) G06F 2212/1016 (20130101) G06F 2212/7206 (20130101) Static Stores G11C 7/04 (20130101) Climate Change Mitigation Technologies in Information and Communication Technologies [ICT] i.e Information and Communication Technologies Aiming at the Reduction of Their Own Energy Use Y02D 10/00 (20180101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/712 (20130101) Y10S 977/714 (20130101) Y10S 977/781 (20130101) Y10S 977/924 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913924 | Cooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Zheng Ouyang (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to ion generation using modified wetted porous materials. In certain aspects, the invention generally relates to systems and methods for ion generation using a wetted porous substrate that substantially prevents diffusion of sample into the substrate. In other aspects, the invention generally relate to ion generation using a wetted porous material and a drying agent. In other aspects, the invention generally relates to ion generation using a modified wetted porous substrate in which at least a portion of the porous substrate includes a material that modifies an interaction between a sample and the substrate. |
| FILED | Thursday, March 30, 2023 |
| APPL NO | 18/128584 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/91 (20130101) G01N 30/95 (20130101) Original (OR) Class G01N 33/49 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0031 (20130101) H01J 49/167 (20130101) H01J 49/168 (20130101) H01J 49/0404 (20130101) H01J 49/0409 (20130101) H01J 49/0431 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913959 | Norton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Larry Norton (New York, New York); Ross Levine (New York, New York); Maria Kleppe (New York, New York); Elizabeth Comen (New York, New York) |
| ABSTRACT | Provided herein are methods of treating a nonhematopoietic malignant tumor in a patient and methods of prognosing a nonhematopoietic malignant tumor in a patient, comprising administering to the patient a therapeutically effective amount of an agent that preferentially kills or inhibits proliferation or activity of leukocytes relative to nonhematopoietic cells. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/207412 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/52 (20130101) A61K 31/506 (20130101) A61K 31/573 (20130101) A61K 31/704 (20130101) A61K 31/7048 (20130101) A61K 31/7052 (20130101) A61K 31/7068 (20130101) A61K 38/177 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) Original (OR) Class G01N 33/57496 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) G01N 2800/7028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913960 | Ferreira |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Toledo (Toledo, Ohio) |
| ASSIGNEE(S) | The University of Toledo (Toledo, Ohio) |
| INVENTOR(S) | Viviana P. Ferreira (Toledo, Ohio) |
| ABSTRACT | Methods measuring properdin function and kits for conducting ELISA Assays using anti-properdin antibodies and uses thereof are described. |
| FILED | Friday, May 10, 2019 |
| APPL NO | 16/408621 |
| ART UNIT | 1677 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) Original (OR) Class G01N 33/543 (20130101) G01N 33/54386 (20130101) G01N 2333/4706 (20130101) G01N 2333/4716 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913963 | Greene et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Mark I. Greene (Penn Valley, Pennsylvania); Douglas B. Cines (Wynnewood, Pennsylvania); Zheng Cai (Wynnewood, Pennsylvania); Zhiqiang Zhu (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention provides a humanized antibody or antibody fragment comprising (a) a humanized light chain comprising 1) Complementarity Determining Region (CDR)-L1, the sequence of which is identical to the sequence of SEQ ID NO: 3; 2) CDR-L2, the sequence of which is identical to the sequence of SEQ ID NO: 4; and 3) CDR-L3, the sequence of which is identical to the sequence of SEQ ID NO: 5, and (b) a humanized heavy chain comprising 1) CDR-H1, the sequence of which is identical to the sequence of SEQ ID NO: 6; 2) CDR-H2, the sequence of which is identical to the sequence of SEQ ID NO: 7; and 3) CDR-H3, the sequence of which is identical to the sequence of SEQ ID NO: 8, as well as methods for treating, diagnosing, and monitoring the progression of HIT. The present invention also provides methods for assessing the antigenicity and ability to cause HIT of anionic anticoagulants. The present invention also provides a mutant protein which has the same amino acid sequence of a wild type PF4 monomer except that (i) at least one amino acid of the wild type PF4 monomer has been deleted, (ii) at least one amino acid of the wild type PF4 monomer has been replaced by another amino acid, or (iii) a combination of such changes has been made. The present invention also provides methods of treating or reducing the likelihood of HIT, treating angiogenesis, treating abnormal cell growth, or affecting coagulation pathologies that lead to thrombus formation, by administering such mutant proteins to a patient. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/929524 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/195 (20130101) A61K 39/3955 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/522 (20130101) C07K 16/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/86 (20130101) G01N 33/6863 (20130101) Original (OR) Class G01N 2333/522 (20130101) G01N 2400/40 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914013 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Yihua (Bruce) Yu (Ellicott City, Maryland); Marc B. Taraban (North Potomac, Maryland) |
| ABSTRACT | A method for using water proton transverse relaxation rate R2(T) to monitor, in real time, the sedimentation rates of multiphase mixtures such as drug products and drug substances. The method provides a practical application of wNMR as an analytical tool to study and provide higher quality and more efficient multiphase mixtures. |
| FILED | Friday, August 13, 2021 |
| APPL NO | 17/401709 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/04 (20130101) G01N 24/082 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) Original (OR) Class G01R 33/34092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914034 | Zhu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Quing Zhu (St. Louis, Missouri); Shiqi Xu (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Quing Zhu (St. Louis, Missouri); Shiqi Xu (St. Louis, Missouri) |
| ABSTRACT | A diffuse optical tomography (DOT) system for generating a functional image of a lesion region of a subject is described. The DOT system includes a source subsystem configured to generate optical waves, a probe coupled to the source subsystem and configured to emit the optical waves generated by the source subsystem toward the lesion region and to detect optical waves reflected by the lesion region, a detection subsystem configured to convert the optical waves detected by the probe to digital signals, and a computing device including a processor and a memory. The memory includes instructions that program the processor to receive the digital signals sent from the detection subsystem and perform reconstruction using a depth-regularized reconstruction algorithm combined with a semi-automated interactive convolutional neural network (CNN) for depth-dependent reconstruction of absorption distribution. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 16/948261 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/52 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52017 (20130101) G01S 15/8906 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 11/003 (20130101) G06T 2207/10132 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914042 | Schaefer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Philip Raymond Schaefer (Weaverville, North Carolina) |
| ASSIGNEE(S) | Vortant Technologies, LLC (Weaverville, North Carolina) |
| INVENTOR(S) | Philip Raymond Schaefer (Weaverville, North Carolina) |
| ABSTRACT | A system shines a series of light stripes across an area. A target object passes through the area and light is reflected to the system from the light stripes as it passes through. Based on the timing of the received light from each of the light stripes, the system calculates the position and velocity of the target object. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/506608 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/68 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914129 | Ha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Taekjip Ha (Baltimore, Maryland); Jong-Chan Lee (Baltimore, Maryland); Ye Ma (Baltimore, Maryland) |
| ABSTRACT | The present invention is directed toward a system and method for STED nanography, which reduces background noise. To remove background noise from a STED image, the polarization of the STED beam is altered from that used to obtain the original image. A polarized image is obtained. This polarized image can then be subtracted from the original image to remove noise inherent to the image. |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 17/598725 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0068 (20130101) G02B 21/0072 (20130101) G02B 21/0076 (20130101) Original (OR) Class G02B 21/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11915417 | Feng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Ruibin Feng (Scottsdale, Arizona); Zongwei Zhou (Tempe, Arizona); Jianming Liang (Scottsdale, Arizona) |
| ABSTRACT | Described herein are means for training a deep model to learn contrastive representations embedded within part-whole semantics via a self-supervised learning framework, in which the trained deep models are then utilized for the processing of medical imaging. For instance, an exemplary system is specifically configured for performing a random cropping operation to crop a 3D cube from each of a plurality of medical images received at the system as input; performing a resize operation of the cropped 3D cubes; performing an image reconstruction operation of the resized and cropped 3D cubes to predict the resized whole image represented by the original medical images received; and generating a reconstructed image which is analyzed for reconstruction loss against the original image representing a known ground truth image to the reconstruction loss function. Other related embodiments are disclosed. |
| FILED | Monday, April 26, 2021 |
| APPL NO | 17/240271 |
| ART UNIT | 4136 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 18/2155 (20230101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/174 (20170101) G06T 15/08 (20130101) G06T 17/10 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20132 (20130101) G06T 2207/30016 (20130101) G06T 2207/30056 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 2201/031 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11911523 | Maitland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE TEXAS A and M UNIVERSITY SYSTEM (College Stataion, Texas) |
| INVENTOR(S) | Duncan J. Maitland (College Station, Texas); Todd Lawrence Landsman (College Station, Texas); Tyler Joseph Touchet (Cypress, Texas); Elizabeth L Cosgriff-Hernandez (College Station, Texas); Thomas S. Wilson (San Leandro, California) |
| ABSTRACT | An embodiment includes a wound dressing comprising: a shape memory polymer (SMP) foam, including open cells, having first and second states; and a hydrogel (HG) included within the cells; wherein (a) in a first position a composite, including the SMP foam and the HG, is configured to be located proximate a hemorrhagic tissue with the SMP foam in the first state; (b) in a second position the composite is configured to be expanded to the second state against the hemorrhagic tissue when the SMP foam is plasticized at 37° C. depressing a glass transition temperature (Tg) of the SMP foam to below 25° C. Other embodiments are described herein. |
| FILED | Tuesday, June 01, 2021 |
| APPL NO | 17/335316 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/00017 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/18 (20130101) Original (OR) Class A61L 15/26 (20130101) A61L 15/26 (20130101) A61L 15/46 (20130101) A61L 15/425 (20130101) A61L 24/0015 (20130101) A61L 24/0036 (20130101) A61L 24/0094 (20130101) A61L 24/0094 (20130101) A61L 2300/106 (20130101) A61L 2300/404 (20130101) A61L 2400/16 (20130101) Compositions of Macromolecular Compounds C08L 75/04 (20130101) C08L 75/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911955 | Cluff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Kyle Cluff (Los Alamos, New Mexico); Matthew Lee (Los Alamos, New Mexico); Nicholas Parra-Vasquez (Los Alamos, New Mexico); Matthew Crall (Los Alamos, New Mexico) |
| ABSTRACT | Disclosed herein are embodiments of a system for use in additive manufacturing methods. The system can comprise a first container, and a first fluid and a second fluid forming a fluid-fluid interface within the first container. The first fluid is between the fluid-fluid interface and the transparent portion of the first container and configured to remove oxygen from the second fluid at the fluid-fluid interface to facilitate polymerization of a monomeric component in the second fluid. The system can also comprise a circulation system configured to circulate the first fluid through the first container such that the first fluid flows between the fluid-fluid interface and the inner surface of the transparent portion of the first container. |
| FILED | Thursday, December 03, 2020 |
| APPL NO | 17/111431 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) Original (OR) Class B29C 64/232 (20170801) B29C 64/245 (20170801) B29C 64/255 (20170801) B29C 64/264 (20170801) B29C 64/343 (20170801) B29C 64/371 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912263 | Aggoune et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
| ASSIGNEE(S) | DELPHI TECHNOLOGIES IP LIMITED (St. Michael, Barbados) |
| INVENTOR(S) | Karim Aggoune (Auburn Hills, Michigan); Peter M. Olin (Ann Arbor, Michigan); Zhaoxuan Zhu (Upper Arlington, Ohio) |
| ABSTRACT | A method for controlling vehicle propulsion includes identifying at least one route characteristic of a portion of a route being traversed by a vehicle. The method further includes determining a profile for a target vehicle speed based on the at least one route characteristic and a vehicle energy consumption profile. The method further includes selectively adjusting a vehicle speed control input based on the target vehicle speed profile. The method further includes communicating the vehicle speed control input to a vehicle propulsion controller to achieve the target vehicle speed profile. |
| FILED | Tuesday, January 14, 2020 |
| APPL NO | 16/742204 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 20/12 (20160101) Original (OR) Class B60W 30/143 (20130101) B60W 30/18072 (20130101) B60W 40/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912589 | Ardo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Shane Ardo (Irvine, California); Samuel Thomas Keene (Irvine, California); Gabriel S. Phun (Irvine, California) |
| ABSTRACT | Photochemical energy conversion is more efficient when a single light-absorbing unit is split into multiple light-absorbing units (N) that are each 1/N as thick as the single light-absorbing unit and thus use the same amount of material as the single light-absorbing unit. For electrocatalytic parameters relevant to water electrolysis, the maximum efficiency for solar-to-fuel conversion from a 1.75 eV bandgap material increases from approximately 1% for a single light-absorbing unit to greater than 20% for 128 identical stacked light-absorbing units. Alterations in utilization of photons results in a better match of the light-absorber power output to the load of the chemical transformation and in the case of high-quality light-absorbers there is an added benefit from radiative coupling between the light-absorbing units via photon recycling. |
| FILED | Monday, November 04, 2019 |
| APPL NO | 16/673680 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4604 (20130101) Original (OR) Class C02F 1/46104 (20130101) C02F 2305/10 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 1/55 (20210101) C25B 9/50 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912825 | Bara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama) |
| ASSIGNEE(S) | The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama) |
| INVENTOR(S) | Jason E. Bara (Tuscaloosa, Alabama); Kathryn E. O'Harra (Tuscaloosa, Alabama); Irshad Kammakakam (Tuscaloosa, Alabama) |
| ABSTRACT | Disclosed are compositions derived from 2,2′bisimidazoles building blocks and methods of making the same. The disclosed compositions are capable of withstanding temperatures up to 600° C. and substantially flame resistant. |
| FILED | Thursday, January 21, 2021 |
| APPL NO | 17/154451 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 235/20 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/18 (20130101) C08G 73/0616 (20130101) Original (OR) Class C08G 73/1039 (20130101) C08G 73/1085 (20130101) Compositions of Macromolecular Compounds C08L 79/04 (20130101) C08L 2205/025 (20130101) C08L 2205/035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912886 | Pearson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Ryan Michael Pearson (Berkeley, California); Matthew David Ryan (Berkeley, California); Garret Miyake (Fort Collins, Colorado) |
| ABSTRACT | Polymer composite photonic crystal materials are disclosed as coatings and topcoats which have high reflection (>30%) in a specific range of the electromagnetic spectrum, such as ultraviolet (<400 nm), visible (Vis, 400 nm-700 nm), or near-infrared radiation range (NIR, 700-2000 nm), and relatively low reflection (<20% reflection) in a second, different range of the electromagnetic spectrum. Surprisingly, it was found that through a formulation and additives approach, the optical properties of polymer composite photonic crystal films can be selectively modified from a variety of different coating methods, including spray deposition. |
| FILED | Thursday, January 30, 2020 |
| APPL NO | 16/964463 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00865 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 299/0485 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 4/00 (20130101) C09D 5/002 (20130101) C09D 7/41 (20180101) C09D 7/61 (20180101) C09D 133/10 (20130101) C09D 153/00 (20130101) C09D 155/005 (20130101) Original (OR) Class C09D 175/14 (20130101) C09D 181/02 (20130101) Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2848 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912927 | Pyatina et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Tatiana Pyatina (Stony Brook, New York); Toshifumi Sugama (Wading River, New York) |
| ABSTRACT | A well cement composite and a method for making a well cement composite includes a mixture of calcium aluminate cement (CAC) and fly ash cenospheres (CS) in a weight ratio of from 30:70 to 80:20 CAC to CS; sodium metasilicate (SMS) in an amount of from 1 to 10% of the total weight of the mixture of CAC and CS; polymethylhydrosiloxane (PMHS) in an amount of from 0.5 to 6.0% of the total weight of the mixture of CAC and CS; and water in a weight ratio of from 0.5:1.0 to 1.2:1.0 of water to CAC and CS. |
| FILED | Tuesday, October 05, 2021 |
| APPL NO | 17/494477 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 7/32 (20130101) C04B 12/04 (20130101) C04B 18/082 (20130101) C04B 18/082 (20130101) C04B 18/082 (20130101) C04B 18/082 (20130101) C04B 20/1037 (20130101) C04B 20/1051 (20130101) C04B 20/1051 (20130101) C04B 24/42 (20130101) C04B 24/42 (20130101) C04B 24/42 (20130101) C04B 28/06 (20130101) C04B 28/06 (20130101) C04B 28/26 (20130101) C04B 28/26 (20130101) C04B 40/0042 (20130101) C04B 2111/27 (20130101) C04B 2111/2084 (20130101) C04B 2201/20 (20130101) C04B 2201/32 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/467 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913016 | Alexander et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | William Gerald Alexander (Madison, Wisconsin); David Peris Navarro (Madison, Wisconsin); Christopher Todd Hittinger (Madison, Wisconsin) |
| ABSTRACT | Methods of making synthetic yeast cells by mating together two diploid (or higher ploidy) yeast species or hybrids to generate multi-ploid yeast hybrids are provided herein. The synthetic yeast cells made by this process and kits for performing the process are also provided. |
| FILED | Tuesday, November 07, 2017 |
| APPL NO | 15/805950 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/18 (20130101) C12N 9/16 (20130101) C12N 15/65 (20130101) C12N 15/81 (20130101) C12N 15/905 (20130101) Original (OR) Class C12N 2800/80 (20130101) C12N 2840/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913090 | Theaker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of North Dakota (Grand Forks, North Dakota) |
| ASSIGNEE(S) | University of North Dakota (Fargo, North Dakota) |
| INVENTOR(S) | Nolan Theaker (Grand Forks, North Dakota); Daniel Laudal (Grand Forks, North Dakota) |
| ABSTRACT | A method for extracting rare earth elements and critical minerals including adding an acid to a mixture comprising organically bound rare earth elements. The mixture is maintained at a pH of 0.25 to 4 for a period of time, resulting in a liquor and a leached mixture. The liquor is removed from the leached mixture to form a dewatered cake. The dewatered cake is washed to form a washing liquid. The washing liquid is recycled to create a second slurry comprising organically bound rare earth elements. |
| FILED | Thursday, November 04, 2021 |
| APPL NO | 17/519341 |
| ART UNIT | 1738 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Separation B01D 11/028 (20130101) B01D 11/0288 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/06 (20130101) C22B 59/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913120 | Jordan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric Jordan (Storrs, Connecticut); Maurice Gell (Somerset, New Jersey); Rishi Kumar (Ashford, Connecticut); Chen Jiang (Willimantic, Connecticut) |
| ABSTRACT | A coating on a substrate is disclosed having layers including yttrium aluminum garnet (YAG) and yttrium aluminum monoclinic (YAM). |
| FILED | Monday, August 01, 2022 |
| APPL NO | 17/878868 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 28/042 (20130101) C23C 28/044 (20130101) C23C 28/3455 (20130101) Original (OR) Class Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/288 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/90 (20130101) F05D 2260/95 (20130101) F05D 2300/21 (20130101) F05D 2300/6111 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913591 | Gorodetsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alon A. Gorodetsky (Irvine, California); Steven R. Jim (Hillsboro, Oregon); George Stiubianu (Iasi, Romania); Erica Leung (Piedmont, California); Kyle Naughton (Laguna Beach, California); Priyam Patel (Irvine, California); Maurizio Follador (Givoletto, Italy); Emil Karshalev (San Diego, California) |
| ABSTRACT | Composite materials with adjustable spectral properties comprised of IR-reflecting micro-domains overlaying an IR-transparent elastomeric matrix, and capable of dynamically controlling IR radiation transmission are described, as well as methods of fabrication thereof. Systems with capabilities to regulate IR radiation (including heat) transmission based thereon, and methods of regulating IR radiation transmission (including thermal regulation) using the same are also provided. |
| FILED | Wednesday, November 27, 2019 |
| APPL NO | 17/297888 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/003 (20130101) B29C 41/04 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2025/08 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/0005 (20130101) C23C 14/16 (20130101) C23C 14/30 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913671 | Poerschke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RHEIA, LLC. (Phoenix, Arizona) |
| ASSIGNEE(S) | RHEIA, LLC (Phoenix, Arizona) |
| INVENTOR(S) | Andrew Poerschke (Pittsburgh, Pennsylvania); Anthony Grisolia (West Leechburg, Pennsylvania); Robert Beach (Pittsburgh, Pennsylvania) |
| ABSTRACT | An indoor environmental control and air distribution system for a building includes: an air handling unit; a manifold connected to the air handling unit having a chamber formed by a plurality of walls and a plurality of orifices formed through at least one of the walls; air distribution conduits each independently having a first end connected to the orifices of the manifold and a second end extending out from the manifold into different zones throughout the building; and an airflow modulating device having one or more airflow regulating dampers independently configured to move into at least two positions in which each position provides a different percentage of total air volume to each air distribution conduit. A method of using the indoor environmental control and air distribution system is also included. |
| FILED | Thursday, March 11, 2021 |
| APPL NO | 17/198797 |
| ART UNIT | 2115 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 3/044 (20130101) Original (OR) Class F24F 13/10 (20130101) F24F 13/14 (20130101) F24F 13/105 (20130101) F24F 2110/10 (20180101) F24F 2110/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913675 | Sampayan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Opcondys, Inc. (Manteca, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); Opcondys, Inc. (Manteca, California) |
| INVENTOR(S) | Stephen Sampayan (Manteca, California); Kristin Cortella Sampayan (Manteca, California) |
| ABSTRACT | Devices, methods and techniques are disclosed to perform high confidence sterilization of indoor air with low power requirements. In one example aspect, a sterilization device includes a power source, an energy storage coupled to the power source and configured to store electric charges, a set of electrodes arranged in a specified geometry to have a fixed characteristic impedance, and a switch positioned between the energy storage and the set of electrodes. The switch is configured to operate to establish a pulsed electric field on the set of electrodes. |
| FILED | Friday, May 21, 2021 |
| APPL NO | 17/327556 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 8/80 (20210101) F24F 8/194 (20210101) Original (OR) Class F24F 11/88 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913827 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Qin Zhou (Fremont, California); Alexander K. Zettl (Kensington, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to an ultrasonic microphone and an ultrasonic acoustic radio. In one aspect a system includes a transmitter and a receiver. The receiver comprises a membrane. The membrane comprises a single layer or multiple layers of a two-dimensional material. The receiver is operable to receive sound waves in a frequency range, with the frequency range being the ultrasonic frequency range. |
| FILED | Wednesday, September 28, 2022 |
| APPL NO | 17/954728 |
| ART UNIT | 2653 — Videophones and Telephonic Communications |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 3/12 (20130101) G01H 11/06 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/104 (20130101) Electric Digital Data Processing G06F 3/0325 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 1/08 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 19/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913830 | Tung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Daniel Tung (Stanley, New Mexico); Randal L Schmitt (Tijeras, New Mexico) |
| ABSTRACT | A laser absorptivity measurement device uses a linearly polarized incident beam, an optical configuration comprising an internal polarizing beamsplitter that transmits the linearly polarized incident beam and a quarter-wave plate that converts linearly polarized incident beam into a circularly polarized incident beam that is reflected off a processing substrate. The quarter-wave plate and polarizing beamsplitter can then direct the reflected light back into an integrating volume, where the power of the reflected light can be measured by a photodetector. The laser absorptivity measurement device is capable of making real-time absorption efficiency measurements of a variety of laser-based processes, including laser welding and brazing, additive manufacturing, and laser marking. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 17/522123 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/0625 (20130101) G01B 11/0641 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) G01J 1/0429 (20130101) Original (OR) Class G01J 2001/446 (20130101) Optical Elements, Systems, or Apparatus G02B 5/3083 (20130101) G02B 27/283 (20130101) G02B 27/286 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913839 | Taylor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Samantha Taylor (West Chester, Ohio); Eric Christopher Forrest (Albuquerque, New Mexico) |
| ABSTRACT | Embodiments of the present disclosure provide an improved method and apparatus for thermal monitoring for a metal additive manufacturing system. An emissivity value of a top surface of an object to be manufactured is determined based, at least in part, on an arithmetic product of a predetermined roughness value and a predetermined slope-related value. The predetermined roughness value and slope-related values are predetermined based, at least in part, on measurements of a previously manufactured object. The system sinters a metal to form the top surface of the object to be manufactured. An infrared sensor detects radiation from at least a portion of the top surface of the object to be manufactured. A temperature is generated based, at least in part, on the detected infrared radiation and the emissivity value and the generated temperature is applied to a temperature utilization component of the system. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 16/876725 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/00 (20210101) B22F 10/10 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/00 (20130101) Original (OR) Class G01J 5/802 (20220101) G01J 2005/0077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913933 | Dong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Liang Dong (Ames, Iowa); Md. Azahar Ali (Ames, Iowa); Xinran Wang (Ames, Iowa); Michael Castellano (Ames, Iowa) |
| ABSTRACT | Apparatus, methods, and systems for transducing measurements from medium of interest. One non-limiting example is in planta monitoring of plants. In one aspect, a micro- or nano-scale probe body includes one or more microprobes (e.g. microneedles or waveguides) to access desired plant tissue, and one or more microsensors on the probe body. A microcircuit on or in the probe body transduces relevant measurements from the microsensor(s). An output interface allows storage, communication, or transfer of the transduced measurement for further use. Non-limiting examples are processing into estimations of chemical concentrations or the like for biochemical sensing. As such, if used as in planta sensors, they can be minimally invasive and cost effective for both single use and use in sets for plural plants with one central station. |
| FILED | Monday, December 28, 2020 |
| APPL NO | 17/247857 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Planting; Sowing; Fertilising A01C 1/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 33/0098 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914018 | Hui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Xiaonan Hui (Ithaca, New York); Edwin C. Kan (Ithaca, New York) |
| ABSTRACT | A radio-frequency method for range finding includes modulating a reference signal having an intermediate frequency to a downlink signal having a carrier frequency using a clock signal. The downlink signal is transmitted to a tag using a transceiver. An uplink signal backscattered front the tag is received and demodulated using the clock signal. The uplink signal has a frequency that is a harmonic of the carrier frequency. A distance between the tag and the transceiver is calculated based on a phase of the demodulated uplink signal. A system for range finding includes a transceiver and a processor. The transceiver modulates a reference signal to downlink signal and transmits the downlink signal. The transceiver receives and demodulates an uplink signal. The processor is configured to receive the demodulated uplink signal and calculate a distance between the tag and the transceiver using a phase of the demodulated uplink signal. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/900480 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/022 (20130101) G01S 1/306 (20130101) Original (OR) Class G01S 1/0428 (20190801) G01S 13/84 (20130101) G01S 13/751 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914188 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jongmin Lee (Albuquerque, New Mexico); Michael Gehl (Edgewood, New Mexico); Grant Biedermann (Norman, Oklahoma); Yuan-Yu Jau (Albuquerque, New Mexico); Christopher T. DeRose (Albuquerque, New Mexico) |
| ABSTRACT | An atom trap integrated platform (ATIP) comprises a substrate, a membrane, and a suspended waveguide. The substrate has an opening formed therein. The membrane extends across a portion of the substrate opening. The suspended waveguide is formed on the membrane such that the suspended waveguide extends from a first edge of the substrate to a second edge. A magneto-optical trap (MOT) is formed around the suspended waveguide by emitting a plurality of cooling beams and a repump through the substrate opening. Evanescent fields are established above the suspended waveguide by coupling two trapping beams through the suspended waveguide, which trapping beams are red-detuned and blue-detuned with respect to the resonant optical transition of the atoms. By forming the MOT within the evanescent fields, an evanescent field optical trap (EFOT) is formed. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 17/546302 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/43 (20130101) G02B 6/1228 (20130101) Original (OR) Class G02B 6/12004 (20130101) G02B 2006/12061 (20130101) G02B 2006/12121 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914357 | Nguyen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Tat Nghia Nguyen (Willowbrook, Illinois); Richard B. Vilim (Sugar Grove, Illinois); Roberto Ponciroli (Chicago, Illinois) |
| ABSTRACT | A method for diagnosing faults includes receiving a description of a component of a thermal hydraulic system, where the description also indicates one or more sensors of the component. The method also includes constructing, based on a physical conservation law and using the description, a physics-based model describing operation of the component, the physics-based model including one or more unknown parameters. The method further includes calibrating the physics-based model by calculating the one or more unknown parameters using historical measurements to produce a calibrated model. Further, the method includes receiving sensor measurements captured by the one or more sensors, and calculating residuals corresponding to differences between measurements predicted by the calibrated model and the sensor measurements. The method also includes determining, based on the calculated residuals, a fault of the component or of a sensor of the one or more sensors, and generating an alert indicating the fault. |
| FILED | Tuesday, December 29, 2020 |
| APPL NO | 17/136572 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 23/024 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/18 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914374 | Yellowhair |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Julius Yellowhair (Albuquerque, New Mexico) |
| ABSTRACT | A system or method for an imaging system is provided for inspecting a heliostat. The imaging system includes a platform and a camera mounted on the platform and a heliostat having a plurality of mirrored facets. The camera is positioned to acquire a first image that serves as a reference image and a second image that is a reflected image from at least one facet. The camera stores image data associated with the first image and the second image, and wirelessly transmits the stored image data to a computing apparatus. The computing apparatus compares the first image with the second image and determines a performance parameter associated with the heliostat. |
| FILED | Wednesday, October 07, 2020 |
| APPL NO | 17/065183 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Unmanned aerial vehicles [UAV]; equipment therefor B64U 2101/30 (20230101) Solar Heat Collectors; Solar Heat Systems F24S 23/74 (20180501) Systems for Controlling or Regulating Non-electric Variables G05D 1/0094 (20130101) Original (OR) Class G05D 1/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914516 | Walker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Dean E. Walker (Allen, Texas); Tony M. Brewer (Plano, Texas) |
| ABSTRACT | System and techniques for memory side cache request handling are described herein. When a memory request is received, a cache set for the memory request is determined. Here, the cache set has multiple ways and each way corresponds to a cache line. It can be detected that a way of the multiple ways is not ready for the memory request. In this case, a representation of the memory request is stored in a queue of multiple queues based on an interface upon which the memory request was received and the present ways of the cache set. Entries from the multiple queues can be dequeued in a defined order to determine a next memory request to process. The defined order gives priority to memory requests for a present way and then for external over internal requests. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823323 |
| ART UNIT | 2135 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0855 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914937 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Virginia Polytechnic Institute and State University (Blacksburg, Virginia) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (, California); VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (, Virginia) |
| INVENTOR(S) | Xiao Chen (Tracy, California); Can Huang (Livermore, California); Liang Min (Pleasanton, California); Charanraj Thimmisetty (Dublin, California); Charles Tong (Danville, California); Yijun Xu (Nanjing, China PRC); Lamine Mili (New Alexandria, Virginia) |
| ABSTRACT | Techniques, systems, and devices are described for providing a computational frame for estimating high-dimensional stochastic behaviors. In one exemplary aspect, a method for performing numerical estimation includes receiving a set of measurements of a stochastic behavior. The set of correlated measurements follows a non-standard probability distribution and is non-linearly correlated. Also, a non-linear relationship exists between a set of system variables that describes the stochastic behavior and a corresponding set of measurements. The method includes determining, based on the set of measurements, a numerical model of the stochastic behavior. The numerical model comprises a feature space comprising non-correlated features corresponding to the stochastic behavior. The non-correlated features have a dimensionality of M and the set of measurements has a dimensionality of N, M being smaller than N. The method includes generating a set of approximated system variables corresponding to the set of measurements based on the numerical model. |
| FILED | Monday, February 13, 2023 |
| APPL NO | 18/108964 |
| ART UNIT | 2148 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 30/27 (20200101) Original (OR) Class G06F 2111/10 (20200101) Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11915837 | Graves et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf Of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | William Graves (Tempe, Arizona); Lucas Malin (Tempe, Arizona) |
| ABSTRACT | A method includes simulating diffraction in a transmission geometry of relativistic electron bunches from a crystallographic structure of a crystal thereby simulating diffraction of the relativistic electron bunches into a plurality of Bragg peaks. The method includes selecting a range of angles between a direction of propagation of the relativistic electron bunches and a normal direction of crystal including an angle at which a diffraction portion is maximized. The method includes sequentially accelerating a plurality of physical electron bunches to relativistic energies toward a physical crystal having the crystallographic structure and diffracting the plurality of physical electron bunches off the physical crystal at different angles and measuring the diffraction portion into the respective Bragg peak at the different angles. The method includes selecting a final angle based on the measured diffraction portion into the respective Bragg peak at the different angles and generating a pulse of light. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 17/378094 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20008 (20130101) G01N 2223/102 (20130101) G01N 2223/0565 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/062 (20130101) Original (OR) Class G21K 2201/061 (20130101) G21K 2201/067 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 4/00 (20130101) X-ray Technique H05G 2/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916187 | Sakamoto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Jeffrey Sakamoto (Ann Arbor, Michigan); Travis Thompson (Ann Arbor, Michigan); Nathan Taylor (Ann Arbor, Michigan) |
| ABSTRACT | Disclosed are electrochemical devices, such as lithium ion battery electrodes, lithium ion conducting solid-state electrolytes, and solid-state lithium ion batteries including these electrodes and solid-state electrolytes. Also disclosed are methods for making such electrochemical devices. Also disclosed are composite electrodes for solid state electrochemical devices. The composite electrodes include one or more separate phases within the electrode that provide electronic and ionic conduction pathways in the electrode active material phase. |
| FILED | Tuesday, August 07, 2018 |
| APPL NO | 16/636509 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/382 (20130101) H01M 4/0471 (20130101) H01M 4/0485 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0074 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916206 | Belharouak et al. |
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| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Ilias Belharouak (Oak Ridge, Tennessee); Yaocai Bai (Oak Ridge, Tennessee); Jianlin Li (Oak Ridge, Tennessee); Rachid Essehli (Oak Ridge, Tennessee) |
| ABSTRACT | A method of recycling lithium-ion batteries is disclosed. The method includes isolating a composite electrode that comprises an electrode material adhered to a current collector with a polyvinylidene difluoride (PVDF) binder from a spent lithium-ion battery. The method also includes contacting the composite electrode in a polyol fluid capable of releasing the PVDF binder from the current collector without substantially altering either component. The composite electrode may be a cathode or an anode. The method also includes rapidly delaminating the electrode material from the current collector to give a free electrode material and a free current collector, and recovering each of the free electrode material and the free current collector from the mixture. The free electrode material may be reused to prepare another composite electrode, as well as a lithium-ion battery comprising the same, which are also disclosed. |
| FILED | Tuesday, February 16, 2021 |
| APPL NO | 17/177120 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916231 | Chiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Yet-Ming Chiang (Weston, Massachusetts); Richard Park (Somerville, Massachusetts); Venkatasubramanian Viswanathan (Pittsburgh, Pennsylvania); Shashank Sripad (Pittsburgh, Pennsylvania); Zijian Hong (Pittsburgh, Pennsylvania); Pinwen Guan (Pittsburgh, Pennsylvania) |
| ABSTRACT | Electrochemical devices, and associated materials and methods, are generally described. In some embodiments, an electrochemical device comprises an electroactive material. The electroactive material may comprise an alloy having a solid phase and a liquid phase that co-exist with each other. As a result, such a composite electrode may have, in some cases, the mechanical softness to permit both high energy densities and an improved current density as compared to, for example, a substantially pure metal electrode. |
| FILED | Friday, April 17, 2020 |
| APPL NO | 16/852308 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/405 (20130101) Original (OR) Class H01M 10/36 (20130101) H01M 10/44 (20130101) H01M 10/0525 (20130101) H01M 2250/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916234 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); David Lam (Chicago, Illinois); Kan-Sheng Chen (Chicago, Illinois); Joohoon Kang (Evanston, Illinois) |
| ABSTRACT | Anhydrous liquid-phase exfoliation of germanium sulfide to provide few-layer germanium sulfide, as can be incorporated into electronic devices such as but not limited to batteries and cells comprising such materials. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/755680 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 17/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/77 (20130101) C01P 2002/82 (20130101) C01P 2002/84 (20130101) C01P 2002/85 (20130101) C01P 2004/04 (20130101) C01P 2004/24 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/5815 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916404 | Pries et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Jason L. Pries (Oak Ridge, Tennessee); Omer C. Onar (Oak Ridge, Tennessee); Gui-Jia Su (Oak Ridge, Tennessee); Veda Galigekere (Oak Ridge, Tennessee); Mostak Mohammad (Oak Ridge, Tennessee) |
| ABSTRACT | A wireless power supply power supply including first tuning circuitry coupled directly to a transmitter, the first tuning circuitry including an LCC configuration. The wireless power supply may include second tuning circuitry coupled directly to switching circuitry (e.g., an inverter) of the power supply, where the second tuning circuitry may be operable to direct power from the switching circuitry to the first tuning circuitry for supply to the transmitter, and where the second tuning circuitry includes a reactance operable to establish inductive operation of the switching circuitry at the switching frequency of the switching circuitry. |
| FILED | Thursday, May 12, 2022 |
| APPL NO | 17/742770 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 53/122 (20190201) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/12 (20160201) Original (OR) Class H02J 50/40 (20160201) H02J 2310/48 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916511 | Atcitty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Urban Electric Power (Pearl River, New York); Arrowhead Center, Inc. (Las Cruces, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia (Albuquerque, New Mexico); Arrowhead Center, Inc. (Las Cruces, New Mexico); Valerio De Angelis (Santa Barbara, California) |
| INVENTOR(S) | Stanley Atcitty (Albuquerque, New Mexico); Valerio De Angelis (Santa Barbara, California); Satishkumar J. Ranade (Las Cruces, New Mexico); Sijo Augustine (Las Cruces, New Mexico); Nataraj Pragallapati (Edison, New Jersey); Olga Lavrova (Las Cruces, New Mexico) |
| ABSTRACT | A DC bus is connected to a PV array, a battery or both, to power a grid connected inverter load on the bus. A system and method is described for controlling current flow on a DC bus regardless of the type of inverter. A converter receives a DC battery voltage. A switching module controls current flow through the converter. A current generator generates a reference current in response to a reference voltage. A comparator connected at the output of the current generator compares the reference current with a battery current and outputs a signal to a controller. The controller generates a reference value. A PWM generator modulates the switch module to control current flow and energy flow between the DC bus and the battery. The current from the DC bus to the inverter is controlled to allow proper grid-connected operation regardless of inverter type. |
| FILED | Wednesday, October 13, 2021 |
| APPL NO | 17/500632 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0068 (20130101) H02J 2300/26 (20200101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/32 (20141201) Original (OR) Class H02S 40/38 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916940 | Abbaszadeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GE Infrastructure Technology LLC (Greenville, South Carolina) |
| INVENTOR(S) | Masoud Abbaszadeh (Clifton Park, New York); Matthew Christian Nielsen (Scotia, New York); Weizhong Yan (Clifton Park, New York); Justin Varkey John (Cohoes, New York) |
| ABSTRACT | According to some embodiments, a system, method, and non-transitory computer readable medium are provided comprising a plurality of real-time monitoring nodes to receive streams of monitoring node signal values over time that represent a current operation of the cyber physical system; and a threat detection computer platform, coupled to the plurality of real-time monitoring nodes, to: receive the monitoring node signal values; compute an anomaly score; compare the anomaly score with an adaptive threshold; and detect that one of a particular monitoring node and a system is outside a decision boundary based on the comparison, and classify that particular monitoring node or system as anomalous. Numerous other aspects are provided. |
| FILED | Monday, April 12, 2021 |
| APPL NO | 17/228191 |
| ART UNIT | 2498 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1425 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916949 | Urias et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Vincent Urias (Albuquerque, New Mexico); Brian P. Van Leeuwen (Albuquerque, New Mexico); Douglas M. Kayatt, Jr. (Albuquerque, New Mexico) |
| ABSTRACT | A computer-implemented method of monitoring activity of devices in a network is provided. The method comprises passively collecting data regarding how the devices access the network, and for each device on the network, identifying all other devices on the network with which the device communicates. All communication traffic from the devices to outside the network is identified. A determination is made if there are any required updates and if patches for the devices execute in a fashion defined as safe. A number of risk indicators for privacy risks are determined according to device communication within the network, device communication to outside the network, and update and patch execution. A visualization of any identified risk factors is displayed to a user through a user interface. |
| FILED | Wednesday, November 18, 2020 |
| APPL NO | 16/951904 |
| ART UNIT | 2495 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/547 (20130101) Information and Communication Technology Specially Adapted for the Internet of Things [IOT] G16Y 40/50 (20200101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) H04L 63/1433 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11917929 | Pan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Wei Pan (San Ramon, California) |
| ABSTRACT | Various embodiments described herein provide for a topological quantum computer that uses edge Majorana quasi-particles to form qubits. An inverted Indium Arsenide (InAs) and Gallium Antimonide (GaSb) heterostructure is disclosed that is a quantum spin Hall insulator. A layer of aluminum can be deposited over a nanotube that is placed across the layers of the heterostructure. Once the nanotube is removed, and a gate is formed on the heterostructure and the heterostructure is cooled so that the aluminum becomes superconducting, helical edge states are formed at the junction of the super conducting aluminum, the InAs, and the GaSb which creates a Majorana zero modes (MZMs) at zero magnetic field. The MZMs can be used to construct a topological qubit for fault-resistant topological quantum computation. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 17/548890 |
| ART UNIT | 2896 — Cable and Television |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Electric solid-state devices not otherwise provided for H10N 60/12 (20230201) H10N 60/805 (20230201) H10N 60/855 (20230201) H10N 60/0912 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11911117 | Haider et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Hani Haider (Carter Lake, Iowa); Ibrahim Al-Shawi (Amman, Jordan); Osvaldo Andres Barrera (Omaha, Nebraska) |
| ABSTRACT | A number of improvements are provided relating to computer aided surgery utilizing an on tool tracking system. The various improvements relate generally to both the methods used during computer aided surgery and the devices used during such procedures. Other improvements relate to the structure of the tools used during a procedure and how the tools can be controlled using the OTT device. Still other improvements relate to methods of providing feedback during a procedure to improve either the efficiency or quality, or both, for a procedure including the rate of and type of data processed depending upon a CAS mode. |
| FILED | Sunday, September 04, 2022 |
| APPL NO | 17/902876 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/3132 (20130101) A61B 5/00 (20130101) A61B 5/061 (20130101) A61B 5/1076 (20130101) A61B 17/142 (20161101) A61B 17/1703 (20130101) A61B 34/20 (20160201) Original (OR) Class A61B 34/37 (20160201) A61B 34/76 (20160201) A61B 2034/102 (20160201) A61B 2034/2057 (20160201) A61B 2034/2065 (20160201) A61B 2090/061 (20160201) A61B 2090/064 (20160201) A61B 2090/3983 (20160201) Image Data Processing or Generation, in General G06T 2207/30004 (20130101) Image or Video Recognition or Understanding G06V 2201/034 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911208 | Salinas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | The Government of the United States, as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Jose Salinas (San Antonio, Texas); Ronald D. Grisell (Spring Branch, Texas); Sena R. Veazey (San Antonio, Texas); Saul J. Vega (San Antonio, Texas) |
| ABSTRACT | Improved systems and methods for diagnosing an injury of a patient. The system and methods provide for more accurate scans of the injury thereby enabling a combat medic, a medical technician, or even untrained individuals to quickly diagnose the injury. By providing more accurate information, the systems and methods provide the technician with additional information regarding treatment options, such as whether to transport the patient or treat the patient in place, potential for aspiration, and other information about dangerous fluid build-up such as size, depth, and types of surrounding tissues, thereby increasing survivability of the patient. The systems and methods can also provide a diagnosis of the injury as well as suggestions on actions to take to treat the patient. |
| FILED | Wednesday, August 21, 2019 |
| APPL NO | 17/269739 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/06 (20130101) Original (OR) Class A61B 8/465 (20130101) A61B 8/469 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0607 (20130101) B06B 2201/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911619 | Chang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Edward F. Chang (San Francisco, California) |
| ABSTRACT | The present disclosure provides a method and system for treating affective disorders such as depression and/or anxiety and/or related disorders through neuromodulatory intervention that includes brain targets within the orbitofrontal cortex (OFC). This method includes the application of electrical stimulation through an electrical signal generator device where the distal end of the device comprises at least one stimulating electrode in contact with the OFC. The treatment system includes patient selection, implantation of at least one stimulating electrode in contact with the OFC, acute or chronic electrical stimulation of the OFC, and evaluation of the effects of stimulation on clinical symptoms and status. |
| FILED | Friday, April 06, 2018 |
| APPL NO | 16/498282 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) A61N 1/0534 (20130101) A61N 1/36021 (20130101) A61N 1/36025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911719 | Brancazio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | David Brancazio (Cambridge, Massachusetts); Allan S. Myerson (Cambridge, Massachusetts); Mohammad A. Azad (Greensboro, North Carolina); Gregory J. Hammersmith (Windsor, Connecticut); Gerard Capellades Mendez (Cambridge, Massachusetts); Clemence Neurohr (Cambridge, Massachusetts); Kersten Rapp (Medway, Massachusetts); Naomi Elizabeth Barbara Briggs (Rockville, Maryland) |
| ABSTRACT | Devices and methods for filtering, drying, and mechanically processing active pharmaceutical ingredients are generally described. |
| FILED | Monday, July 20, 2020 |
| APPL NO | 16/933158 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 3/10 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) Separation B01D 29/05 (20130101) B01D 29/075 (20210801) B01D 29/86 (20130101) Original (OR) Class B01D 29/608 (20130101) B01D 35/18 (20130101) B01D 2201/204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912385 | Ripplinger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battle Sight Technologies, LLC (Dayton, Ohio) |
| ASSIGNEE(S) | Battle Sight Technologies, LLC (Dayton, Ohio) |
| INVENTOR(S) | Nicholas R. Ripplinger (Springboro, Ohio); Christopher J. Vogt (Cincinnati, Ohio) |
| ABSTRACT | An apparatus that facilitates search and rescue, for example, in open water. The apparatus comprises a substrate with a particular geometry and a perimeter. The apparatus further comprises a cover positioned atop the substrate with the cover also having a particular geometry and perimeter, which correspond to the geometry and perimeter of the substrate. An air-tight seal seals the substrate perimeter to the cover perimeter and creates a sealed internal region. A breakable vessel holding an activator is located in the sealed internal region, along with illuminable dyes that are also located in the sealed internal region. When the breakable vessel is broken, the activator reacts with the illuminable dyes and illuminates the illuminable dyes. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/194031 |
| ART UNIT | 3617 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 9/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912606 | Gibson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Daniel J. Gibson (Falls Church, Virginia); Daniel Rhonehouse (Chesapeake Beach, Maryland); Shyam S. Bayya (Ashburn, Virginia); L. Brandon Shaw (Woodbridge, Virginia); Rafael R. Gattass (Washington, District of Columbia); Jesse A. Frantz (Washington, District of Columbia); Jason D. Myers (Alexandria, Virginia); Woohong Kim (Lorton, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
| ABSTRACT | This application relates generally to an optical fiber for the delivery of infrared light where the polarization state of the light entering the fiber is preserved upon exiting the fiber and the related methods for making thereof. The optical fiber has a wavelength between about 0.9 μm and 15 μm, comprises at least one infrared-transmitting glass, and has a polarization-maintaining (PM) transverse cross-sectional structure. The infrared-transmitting, polarization-maintaining (IR-PM) optical fiber has a birefringence greater than 10−5 and has applications in dual-use technologies including laser power delivery, sensing and imaging. |
| FILED | Tuesday, April 07, 2020 |
| APPL NO | 16/842033 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 37/023 (20130101) C03B 37/0122 (20130101) C03B 37/0279 (20130101) C03B 37/01217 (20130101) Original (OR) Class C03B 37/01222 (20130101) C03B 37/01225 (20130101) C03B 37/02709 (20130101) C03B 2201/86 (20130101) C03B 2203/34 (20130101) C03B 2203/302 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 25/005 (20130101) C03C 25/1063 (20180101) Optical Elements, Systems, or Apparatus G02B 6/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912946 | Seibert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Michael Seibert (Bel Air, Maryland); Richard Scenna (Baltimore, Maryland); Terry DuBois (Forest Hill, Maryland) |
| ABSTRACT | Various embodiments that pertain to fuel processing are described. A fuel processor can produce an endothermic reaction that cools a substance and produces a processed fuel from a raw fuel. A generator can employ the processed fuel to produce an electricity. The generator can supply the electricity to a load that uses the electricity to function. The load can become hot due to its functioning and can benefit from being cooled. The substance cooled by the fuel processor can cool load and in the process the substance can rise in temperature. This warmer substance can be transferred to the fuel processor to be cooled again and this cycle can continue. Further, the fuel processor can use the warmer substance to achieve the endothermic reaction. |
| FILED | Monday, March 29, 2021 |
| APPL NO | 17/215498 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/34 (20130101) C01B 2203/06 (20130101) C01B 2203/0233 (20130101) C01B 2203/0883 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 9/40 (20130101) Original (OR) Class C10G 2300/4081 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 1/05 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/764 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912991 | Ellington et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Andrew Ellington (Austin, Texas); Jared Ellefson (Austin, Texas); Jimmy Gollihar (Austin, Texas) |
| ABSTRACT | Embodiments of the disclosure concern methods and compositions related to generation and/or use of proofreading reverse transcriptases, including those that are thermophilic or hyperthermophilic. The disclosure encompasses specific recombinant polymerases and their use. In some embodiments, the polymerases are utilized for RNA sequencing in the absence of generation of a cDNA intermediate. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/098196 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1276 (20130101) C12N 15/1096 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913040 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Basil Hubbard (Cambridge, Massachusetts); Ahmed Hussein Badran (Cambridge, Massachusetts) |
| ABSTRACT | Engineered transcriptional activator-like effectors (TALEs) are versatile tools for genome manipulation with applications in research and clinical contexts. One current drawback of TALEs is that the 5′ nucleotide of the target is specific for thymine (T). TALE domains with alternative 5′ nucleotide specificities could expand the scope of DNA target sequences that can be bound by TALEs. Another drawback of TALEs is their tendency to bind and cleave off-target sequence, which hampers their clinical application and renders applications requiring high-fidelity binding unfeasible. This disclosure provides methods and strategies for the continuous evolution of proteins comprising DNA-binding domains, e.g., TALE domains. In some aspects, this disclosure provides methods and strategies for evolving such proteins under positive selection for a desired DNA-binding activity and/or under negative selection against one or more undesired (e.g., off-target) DNA-binding activities. Some aspects of this disclosure provide engineered TALE domains and TALEs comprising such engineered domains, e.g., TALE nucleases (TALENs), TALE transcriptional activators, TALE transcriptional repressors, and TALE epigenetic modification enzymes, with altered 5′ nucleotide specificities of target sequences. Engineered TALEs that target ATM with greater specificity are also provided. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/355735 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0066 (20130101) A61K 48/0091 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/62 (20130101) C12N 15/90 (20130101) C12N 15/8509 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913052 | Jewett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Ashty Stephen Karim (Chicago, Illinois); Jian Li (Evanston, Illinois); Quentin Dudley (Evanston, Illinois) |
| ABSTRACT | Disclosed are cell-free systems for metabolic engineering, methods for cell-free metabolic engineering, kits for preparing the disclosed systems, and kits for performing the disclosed methods. The disclosed systems, methods, and kits may be utilized to prepare a chemical product or natural product and to optimize conditions for preparing a chemical product or natural product. The disclosed systems, methods, and kits also may be utilized for combinatorial cell-free metabolism engineering. |
| FILED | Monday, March 02, 2020 |
| APPL NO | 16/807147 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913059 | Glaros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Chemical Biological Center (APG, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Trevor G Glaros (North East, Maryland); Elizabeth S Dhummakupt (Abingdon, Maryland); Phillip M Mach (Edgewood, Maryland); Daniel O Carmany (Belcamp, Maryland) |
| ABSTRACT | An apparatus and method for detecting an analyte of interest using paper spray mass spectrometry includes a spray material; a sample on the spray material including an enzyme of interest; a solvent to hydrate the sample, promote enzymatic activity, and extract analytes of interest from the sample; a substrate specific to the enzyme of interest, wherein any of the spray material and the solvent includes the substrate; a voltage source to apply a voltage to the spray material to create charged droplets of a mixture containing the sample; and a mass spectrometer to perform spectrometry on the droplets to perform any of: identify the analytes of interest in the sample; and measure a level of inhibition in any enzymes contained in the sample. |
| FILED | Tuesday, October 26, 2021 |
| APPL NO | 17/511033 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/46 (20130101) Original (OR) Class Enzymes C12Y 301/01007 (20130101) C12Y 301/01008 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) G01N 2560/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/168 (20130101) H01J 49/0445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913076 | Srivastava et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| ASSIGNEE(S) | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| INVENTOR(S) | Shiv K. Srivastava (Potomac, Maryland); Gyorgy Petrovics (Bethesda, Maryland); Indu Kohaar (North Potomac, Maryland) |
| ABSTRACT | The present disclosure provides gene expression profiles that are associated with prostate cancer, including certain gene expression profiles that differentiate between subjects of African and Caucasian descent and other gene expression profiles that are common to subjects of both African and Caucasian descent. The gene expression profiles can be measured at the nucleic acid or protein level and used to stratify prostate cancer based on ethnicity. The gene expression profiles can also be used to identify a subject for prostate cancer treatment. Also provided are kits for diagnosing and prognosing prostate cancer and an array comprising probes for detecting the unique gene expression profiles associated with prostate cancer in subjects of African and/or Caucasian descent. |
| FILED | Tuesday, May 08, 2018 |
| APPL NO | 16/611692 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) G16B 25/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913146 | Fairchild et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Steven B. Fairchild (Beavercreek, Ohio); John J. Boeckl (London, Ohio); Genevieve Dion (Philadelphia, Pennsylvania); Chelsea Amanatides (Philadelphia, Pennsylvania) |
| ABSTRACT | An electrode comprising a conductive textile structure having an inner surface that is connected to one of an electrical power supply and an electrical ground; the conductive textile structure having an outer surface, the outer surface comprising a carbon nanotube (CNT) fiber fabric fixed thereon, the CNT fiber fabric having continuous CNT fiber on the outer surface, wherein the CNT fiber fabric comprises at least one of a CNT fiber, and is at least one of knitted, woven, sewn, and embroidered. The continuous CNT fiber may be a yarn, ribbon, or thread. The CNT fiber fabric includes at least one face having a looped or interlaced structure made from the continuous CNT fiber. The CNT fiber yarn, ribbon, or thread is knitted, woven, sewn, and/or embroidered so that at least one surface comprises a textile made with CNT fiber yarns, ribbons, or threads. |
| FILED | Monday, July 20, 2020 |
| APPL NO | 16/933048 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) Woven Fabrics; Methods of Weaving; Looms D03D 1/00 (20130101) D03D 15/275 (20210101) Knitting D04B 1/04 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/122 (20130101) D10B 2401/16 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 1/304 (20130101) H01J 2201/30469 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913343 | Paulino et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Jose R. Paulino (Saco, Maine); Veronika Reynolds (Lawrence, Massachusetts); Jason David Liles (Port Saint Lucie, Florida) |
| ABSTRACT | A replaceable rotor blade tip clearance measurement device for a gas turbine engine, includes a threaded section along an axis and an integral abradable tip with an internal lattice geometry that extends from the threaded section along the axis. |
| FILED | Thursday, October 03, 2019 |
| APPL NO | 16/592001 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/122 (20130101) F01D 21/003 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/80 (20130101) F05D 2240/55 (20130101) F05D 2250/15 (20130101) F05D 2250/141 (20130101) F05D 2250/283 (20130101) F05D 2270/821 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913374 | Buchanan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Gregory Buchanan (King George, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy Chief of Naval Research, Office of Counsel (Arlington, Virginia) |
| INVENTOR(S) | William Gregory Buchanan (King George, Virginia) |
| ABSTRACT | An internal combustion rotary engine that produces mechanical torque is provided. The engine includes an annular planar housing, a rotor, and first and second valves. The planar housing has a substantially circular annulus flanked by first and second cavities and an axial shaft disposed between the cavities. The rotor is disposed on the shaft and rotates within the annulus; The first and second valves are disposed within respective the cavities. Each valve has an arc wedge having outer convex surface and an inner concave surface, a shaft hole between and parallel to the surfaces along a rocking axis, and a pivot shaft that passes through the shaft hole to enable the wedge to rock back and forth within the cavity. |
| FILED | Tuesday, August 23, 2022 |
| APPL NO | 17/894010 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary-piston or Oscillating-piston Machines or Engines F01C 1/22 (20130101) Cyclically Operating Valves for Machines or Engines F01L 1/18 (20130101) Internal-combustion Piston Engines; Combustion Engines in General F02B 53/00 (20130101) F02B 53/06 (20130101) F02B 53/10 (20130101) F02B 53/12 (20130101) Original (OR) Class F02B 55/00 (20130101) F02B 55/02 (20130101) F02B 55/08 (20130101) F02B 55/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913410 | Hargather et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | X-Bow Launch Systems Inc. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | X-Bow Launch Systems Inc. (Albuquerque, New Mexico) |
| INVENTOR(S) | Chelsey Hargather (Socorro, New Mexico); Mark Kaufman (Auburn, California); Michael McPherson (Socorro, New Mexico); Jillian Marsh (Austin, Texas); Matthew Hinton (Socorro, New Mexico); Dane Fradenburg (Socorro, New Mexico); Maureen Gannon (San Francisco, California); Jason Hundley (Albuquerque, New Mexico); Michael Hargather (Socorro, New Mexico) |
| ABSTRACT | A method of making a fuel grain for use in a rocket motor, the method comprising blending a first energetic nanoscale metallic compound and a second compound suitable to form a feedstock material for use in an additive manufacturing apparatus, the additive manufacturing apparatus operatively connected to a computing system, that provides additive manufacturing printing instructions to the additive manufacturing apparatus, permitting construction of an autonomously designed and optimized rocket fuel grain section; wherein the stochastic deposition simulation-assisted fuel grain geometries further comprise a plurality of agglutinated layers of solidified fuel grain compound, each layer of the plurality of layers comprising a plurality of blended and radially displaced beads of different radii, said radial displacement optionally optimized via competitive simulation programs, and wherein the system continuously mixes constituent materials in an inline/static mixer, with viscosity controlled via particle size variations, and material is deposited in a controlled atmosphere or vacuum. |
| FILED | Thursday, May 20, 2021 |
| APPL NO | 17/325565 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/314 (20170801) B29C 64/371 (20170801) B29C 64/386 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2055/02 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/20 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/00 (20141201) B33Y 50/00 (20141201) B33Y 70/10 (20200101) Jet-propulsion Plants F02K 9/10 (20130101) F02K 9/18 (20130101) F02K 9/24 (20130101) Original (OR) Class F02K 9/72 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913591 | Gorodetsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alon A. Gorodetsky (Irvine, California); Steven R. Jim (Hillsboro, Oregon); George Stiubianu (Iasi, Romania); Erica Leung (Piedmont, California); Kyle Naughton (Laguna Beach, California); Priyam Patel (Irvine, California); Maurizio Follador (Givoletto, Italy); Emil Karshalev (San Diego, California) |
| ABSTRACT | Composite materials with adjustable spectral properties comprised of IR-reflecting micro-domains overlaying an IR-transparent elastomeric matrix, and capable of dynamically controlling IR radiation transmission are described, as well as methods of fabrication thereof. Systems with capabilities to regulate IR radiation (including heat) transmission based thereon, and methods of regulating IR radiation transmission (including thermal regulation) using the same are also provided. |
| FILED | Wednesday, November 27, 2019 |
| APPL NO | 17/297888 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/003 (20130101) B29C 41/04 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2025/08 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/0005 (20130101) C23C 14/16 (20130101) C23C 14/30 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913683 | Pauzauskie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Peter J. Pauzauskie (Seattle, Washington); Anupum Pant (Seattle, Washington); Xiaojing Xia (Seattle, Washington); Elena Dobretsova (Seattle, Washington); E. James Davis (Seattle, Washington); Alexander B. Bard (Seattle, Washington); Robert G. Felsted (Seattle, Washington) |
| ABSTRACT | An apparatus and method of indirectly cooling an optomechanical resonator, comprising impinging a laser on an optomechanical resonator attached to a substrate, wherein the optomechanical resonator comprises a cantilever, a cooling end of the cantilever, having a cooling end comprising a laser-induced cooling element, an attachment end of the cantilever, attached to a substrate, and wherein the laser has a peak wavelength in the near-infrared band. |
| FILED | Tuesday, January 19, 2021 |
| APPL NO | 17/152572 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 23/00 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0408 (20130101) H01S 3/1618 (20130101) H01S 3/1645 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913697 | Ferrara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Peter J. Ferrara (Westampton, New Jersey); Jacob T. Kephart (Garnet Valley, Pennsylvania); Avi Friedman (Bethesda, Maryland) |
| ABSTRACT | A pneumatic cryocooler using a pneumatic motor for use in cryogenically cooling superconductors, which pneumatic cryocooler is capable of operation in strong magnetic fields. |
| FILED | Monday, June 29, 2020 |
| APPL NO | 16/946592 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 9/14 (20130101) Original (OR) Class F25B 2309/003 (20130101) F25B 2309/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913827 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Qin Zhou (Fremont, California); Alexander K. Zettl (Kensington, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to an ultrasonic microphone and an ultrasonic acoustic radio. In one aspect a system includes a transmitter and a receiver. The receiver comprises a membrane. The membrane comprises a single layer or multiple layers of a two-dimensional material. The receiver is operable to receive sound waves in a frequency range, with the frequency range being the ultrasonic frequency range. |
| FILED | Wednesday, September 28, 2022 |
| APPL NO | 17/954728 |
| ART UNIT | 2653 — Videophones and Telephonic Communications |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 3/12 (20130101) G01H 11/06 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/104 (20130101) Electric Digital Data Processing G06F 3/0325 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 1/08 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 19/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913835 | Ledbetter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vector Atomic, Inc. (Pleasanton, California) |
| ASSIGNEE(S) | Vector Atomic, Inc. (Pleasanton, California) |
| INVENTOR(S) | Micah Perry Ledbetter (Sunnyvale, California); Martin Machai Boyd (Pleasanton, California); Andrew Vernon Dowd (Pleasanton, California); William David Lunden (Dublin, California); Jonathan David Roslund (Pleasanton, California) |
| ABSTRACT | Embodiments herein describe spectroscopy systems that use an unmodulated reference optical signal to mitigate noise, or for other advantages. In one embodiment, the unmodulated reference optical signal is transmitted through the same vapor cell as a modulated pump optical signal. As such, the unmodulated reference optical signal experiences absorption by the vapor, which converts laser phase noise to amplitude noise like the other optical signals passing through the vapor cell. In one embodiment, the unmodulated reference optical signal has an optical path in the gas cell that is offset (or non-crossing) from the optical path of the modulated pump optical signal. The unmodulated reference optical signal allows removal or mitigation of the noise on the other optical signal. |
| FILED | Monday, July 17, 2023 |
| APPL NO | 18/353175 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/4338 (20130101) Original (OR) Class G01J 2003/4332 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914263 | Buckwalter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | James F. Buckwalter (Santa Barbara, California); Navid Hosseinzadeh (Goleta, California); Aditya Jain (Goleta, California); Roger Helkey (Santa Barbara, California) |
| ABSTRACT | A predistorter for an electro-optical converter includes a plurality of low noise RF amplifiers distributed along a transmission line that receive an RF input. Second order intermodulation injection (IM2) circuitry includes an inductively-degenerated frequency doubler to square and filter IM2 products of the RF input. A Mach-Zehnder Modulator (MZM) is used for electro-optical conversion. Feed forward circuitry injects IM2 to independently propagate RF intermodulation components with velocity matching to the MZM. At least one driver injects the RF input and RF intermodulation components into the MZM. |
| FILED | Tuesday, March 10, 2020 |
| APPL NO | 17/437979 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/212 (20210101) G02F 1/2255 (20130101) Original (OR) Class Amplifiers H03F 1/32 (20130101) H03F 3/189 (20130101) H03F 2200/451 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914415 | Carolan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jacques Johannes Carolan (Cambridge, Massachusetts); Mihika Prabhu (Cambridge, Massachusetts); Scott A. Skirlo (Boston, Massachusetts); Yichen Shen (Cambridge, Massachusetts); Marin Soljacic (Belmont, Massachusetts); Dirk Englund (Brookline, Massachusetts); Nicholas C. Harris (Boston, Massachusetts) |
| ABSTRACT | An optical neural network is constructed based on photonic integrated circuits to perform neuromorphic computing. In the optical neural network, matrix multiplication is implemented using one or more optical interference units, which can apply an arbitrary weighting matrix multiplication to an array of input optical signals. Nonlinear activation is realized by an optical nonlinearity unit, which can be based on nonlinear optical effects, such as saturable absorption. These calculations are implemented optically, thereby resulting in high calculation speeds and low power consumption in the optical neural network. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 17/736667 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/212 (20210101) G02F 1/225 (20130101) G02F 1/365 (20130101) G02F 1/3526 (20130101) G02F 3/024 (20130101) G02F 2202/32 (20130101) G02F 2203/15 (20130101) Optical Computing Devices; G06E 3/005 (20130101) Original (OR) Class G06E 3/006 (20130101) G06E 3/008 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) G06N 3/084 (20130101) G06N 3/0675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11915105 | Steingrimsson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baldur Andrew Steingrimsson (Hillsboro, Oregon) |
| ASSIGNEE(S) | IMAGARS LLC (Wilsonville, Oregon) |
| INVENTOR(S) | Baldur Andrew Steingrimsson (Hillsboro, Oregon); Peter K Liaw (Knoxville, Tennessee); Xuesong Fan (Knoxville, Tennessee); Anand A Kulkarni (Charlotte, North Carolina); Duckbong Kim (Cookeville, Tennessee) |
| ABSTRACT | This invention presents an innovative framework for the application of machine learning for identification of alloys or composites with desired properties of interest. For each output property of interest, we identify the corresponding driving (input) factors. These input factors may include the material composition, heat treatment, process, microstructure, temperature, strain rate, environment or testing mode. Our framework assumes selection of optimization technique suitable for the application at hand and data available, starting with simple linear, or quadratic, regression analysis. We present a physics-based model for predicting the ultimate tensile strength, a model that accounts for physical dependencies, and factors in the underlying physics as a priori information. In case an artificial neural network is deemed suitable, we suggest employing custom kernel functions consistent with the underlying physics, for the purpose of attaining tighter coupling, better prediction, and extracting the most out of the—usually limited—input data available. |
| FILED | Wednesday, February 05, 2020 |
| APPL NO | 16/782829 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/22 (20210101) B22F 10/25 (20210101) B22F 10/28 (20210101) B22F 10/36 (20210101) B22F 10/80 (20210101) B22F 10/85 (20210101) B22F 10/366 (20210101) B22F 10/368 (20210101) B22F 12/45 (20210101) B22F 12/90 (20210101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) B29C 64/268 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 70/10 (20200101) Electric Digital Data Processing G06F 18/211 (20230101) G06F 18/213 (20230101) G06F 30/27 (20200101) G06F 2113/10 (20200101) G06F 2119/08 (20200101) Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) G06N 20/00 (20190101) Original (OR) Class Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/30 (20190201) G16C 20/70 (20190201) G16C 60/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916135 | Ontalus et al. |
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| FUNDED BY |
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| APPLICANT(S) | GLOBALFOUNDRIES U.S. Inc. (Malta, New York) |
| ASSIGNEE(S) | GLOBALFOUNDRIES U.S. Inc. (Malta, New York) |
| INVENTOR(S) | Viorel Ontalus (Unionville, Connecticut); Justin C. Long (Poughkeepsie, New York); Robert K. Baiocco (Poughquag, New York) |
| ABSTRACT | The present disclosure relates to semiconductor structures and, more particularly, to a bipolar transistor and methods of manufacture. The structure includes: a collector region in a semiconductor substrate; a base region adjacent to the collector region; and an emitter extending above the base region and comprising semiconductor material and a hardmask surrounding a lower portion of the semiconductor material. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 17/587347 |
| ART UNIT | 2821 — Optics |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/732 (20130101) Original (OR) Class H01L 29/0804 (20130101) H01L 29/1004 (20130101) H01L 29/66287 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916159 | Hart et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| INVENTOR(S) | John Hart (Albuquerque, New Mexico); Daniel Derkacs (Albuquerque, New Mexico); Zachary Bittner (Albuquerque, New Mexico); Andrew Espenlaub (Albuquerque, New Mexico) |
| ABSTRACT | A multijunction solar cell including an upper first solar subcell having a first band gap and positioned for receiving an incoming light beam; and a second solar subcell disposed below and adjacent to and lattice matched with said upper first solar subcell, and having a second band gap smaller than said first band gap; wherein at least one of the solar subcells has a graded band gap throughout the thickness of at least a portion of its emitter layer and base layer. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 17/986663 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/065 (20130101) H01L 31/184 (20130101) H01L 31/0725 (20130101) Original (OR) Class H01L 31/0735 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916260 | Milnes et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | L3 Open Water Power, Inc. (Somerville, Massachusetts) |
| ASSIGNEE(S) | L3Harris Open Water Power, Inc. (Somerville, Massachusetts) |
| INVENTOR(S) | Thomas B. Milnes (Beverly, Massachusetts); Ian McKay (Seattle, Washington); Thomas Humplik (Albuquerque, New Mexico) |
| ABSTRACT | Systems, methods, and apparatus configured for the osmotic injection of water in electrochemical systems are generally described. In certain embodiments, water can be transported from a water-containing liquid in an environment outside the electrochemical cell into the electrochemical cell across an osmotic medium fluidically separating an interior compartment of the electrochemical cell from the environment outside the electrochemical cell. The systems, methods, and apparatus described herein can be, according to certain embodiments, configured to be part of an electrochemical system in which water is consumed (e.g., as a reactant). |
| FILED | Wednesday, September 02, 2015 |
| APPL NO | 15/508927 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/34 (20130101) Original (OR) Class H01M 8/227 (20130101) H01M 8/04149 (20130101) H01M 8/04186 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916315 | Underwood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Brandon Underwood (Brick Township, New Jersey); Glenn Minko (Staten Island, New York) |
| ABSTRACT | Various embodiments that relate to a circular disk configured to radiate a signal. The radiating disk can include edge openings. Within these edge openings power supplies can rest. When the power supplies function, they can cause the circular disk to radiate with either a dipole pattern or a cardioid pattern. A controller can manage how these power supplies function depending on if the dipole pattern or the cardioid pattern is desired. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 17/522950 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 5/40 (20150115) H01Q 9/045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916351 | Kaneda |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Yushi Kaneda (Tucson, Arizona) |
| ABSTRACT | Methods, devices and systems for improving single-frequency operation of diode lasers are described. One such method includes ramping up an operational current of a diode laser for a first predetermined number of steps, and measuring an associated current value indicative of optical power within the laser diode for each of the first predetermined number of steps. Next, operational current of the diode laser is ramped down for a second predetermined number of steps, and an associated current value indicative of optical power within the laser diode is measured for each of the second predetermined number of steps. Using the measured data current values at which a mode hop or a multimode operation is likely to occur are identified, and a contiguous range of operating currents that is devoid of identified likely mode hops or multimode regions of operation is determined as the operating current range of the diode laser. |
| FILED | Friday, July 26, 2019 |
| APPL NO | 17/263686 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/354 (20210101) G02F 1/3507 (20210101) G02F 1/3551 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/0092 (20130101) Original (OR) Class H01S 5/141 (20130101) H01S 5/0617 (20130101) H01S 5/0653 (20130101) H01S 5/06808 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916522 | Zurek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Philip Zurek (Boulder, Colorado); Zorana Popovic (Boulder, Colorado) |
| ABSTRACT | A wideband amplifier includes a first diplexer receiving broadband input signals and divides them by frequency into a low band input signal and a high band input signal. The amplifier has separate high band and low band amplifiers coupled to amplify the low and high band input signals, and a second diplexer coupled to combine outputs of the low and high band amplifiers to form a wideband output. A method of amplification of an input signal includes separating the input signal into high and low band signals, separately amplifying the high and low band signals, and combining amplified high and low band signals into an output signal. |
| FILED | Thursday, May 20, 2021 |
| APPL NO | 17/326283 |
| ART UNIT | 2414 — Multiplex and VoIP |
| CURRENT CPC | Amplifiers H03F 1/56 (20130101) H03F 3/245 (20130101) Original (OR) Class H03F 2200/165 (20130101) H03F 2200/171 (20130101) H03F 2200/451 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 5/1438 (20130101) H04L 25/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916933 | Stavrou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | George Mason Research Foundation, Inc. (Fairfax, Virginia) |
| ASSIGNEE(S) | George Mason Research Foundation, Inc. (Fairfax, Virginia) |
| INVENTOR(S) | Angelos Stavrou (Springfield, Virginia); Sushil Jajodia (Oakton, Virginia); Anup K. Ghosh (Centreville, Virginia); Rhandi Martin (St. James, Barbados); Charalampos Andrianakis (Crete, Greece) |
| ABSTRACT | A transparent proxy for malware detection includes a monitor module, a protocol determination module, a challenge generation module, a response determination module, and a data control module. The monitor module examines data originating from an application towards a remote server. The protocol determination module identifies the protocol type used for the data. The challenge generation module produces a challenge for the application based upon the protocol type, sends the challenge to the application, and maintains a state related to the data and the challenge. The response determination module makes a determination if an automatic non-interactive application response is received in response to the challenge from the application. The data control module allows the first data to continue to the remote server when the determination is valid. The data control module reports malware detection and blocks the data to continue to the remote server when the determination is invalid. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 17/736507 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/566 (20130101) G06F 2221/2103 (20130101) G06F 2221/2119 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) H04L 63/145 (20130101) H04L 63/0884 (20130101) H04L 63/1416 (20130101) Original (OR) Class H04L 67/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11917337 | Shreve et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | XEROX CORPORATION (Norwalk, Connecticut) |
| INVENTOR(S) | Matthew A. Shreve (Webster, New York); Eric Cocker (Redwood City, California) |
| ABSTRACT | The present specification relates to image capture. More specifically, it relates to selective image capture for sensor carrying devices or floats deployed, for example, on the open sea. In one form, data is generated on the sensor carrying devices or floats by an on-board Inertial Measurement Unit (IMU) and is used to automatically predict the wave motion of the sea. These predictions are then used to determine an acceptable set of motion parameters that are used to trigger the on-board camera(s). The camera(s) then capture images. One consideration is that images captured at or near the peak of a wave crest with minimal pitch and roll will contain fewer obstructions (such as other waves). Such images provide a view further into the horizon to, for example, monitor maritime sea traffic and other phenomenon. Therefore, the likelihood of capturing interesting objects such as ships, boats, garbage, birds, . . . etc. is increased. These images may then be further processed and/or transmitted in a variety of manners. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 17/463433 |
| ART UNIT | 2426 — Cable and Television |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 79/15 (20200101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 13/004 (20130101) Pictorial Communication, e.g Television H04N 7/188 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11911330 | Deshpande et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Ashish Warren Deshpande (Austin, Texas); Bongsu Kim (Austin, Texas) |
| ABSTRACT | A robotic exoskeleton including a back portion providing at least two degrees of freedom, two shoulder portions, each shoulder portion providing at least five degrees of freedom, two elbow portions, each elbow portion providing at least one degree of freedom, and two forearm portions, each forearm portion providing at least one degree of freedom. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346392 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) A61F 2/76 (20130101) A61F 2/78 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/02 (20130101) Original (OR) Class A61H 1/0274 (20130101) A61H 1/0277 (20130101) A61H 1/0281 (20130101) A61H 2201/165 (20130101) A61H 2201/1207 (20130101) A61H 2201/1215 (20130101) A61H 2201/1454 (20130101) A61H 2201/1481 (20130101) A61H 2201/1614 (20130101) A61H 2201/1616 (20130101) A61H 2201/1619 (20130101) A61H 2201/1621 (20130101) A61H 2201/1638 (20130101) A61H 2201/1676 (20130101) A61H 2201/5058 (20130101) A61H 2201/5061 (20130101) A61H 2201/5064 (20130101) A61H 2201/5069 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911625 | Babakhani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); Texas Heart Institute (Houston, Texas) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Texas Heart Institute (Houston, Texas) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Hongming Lyu (Shanghai, China PRC); Razavi Mehdi (Houston, Texas); Mathews M. John (Houston, Texas); Allison Post (Houston, Texas) |
| ABSTRACT | Systems and methods for heart stimulation in accordance with embodiments of the invention are illustrated. One embodiment includes a heart stimulation system, including a first wirelessly powered, leadless pacemaker, including a wireless power receiver tuned to a first frequency, an energy harvesting circuitry, a stimulation circuitry, and a stimulation electrode, a controller, including a wireless power signal generator, a wireless power transmitter tuned to the frequency, a processor, and a memory containing a stimulation control application, where the stimulation control application directs the processor to generate a power transfer signal using the first wireless power signal generator, and transmit the power transfer signal using the wireless power transmitter, wherein the wirelessly powered, leadless pacemaker receives the power transfer signal using the first wireless power receiver, and when receiving the power transfer signal, the energy harvesting circuitry stores power received via the wireless power receiver in at least one capacitor. |
| FILED | Wednesday, November 20, 2019 |
| APPL NO | 17/295005 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3684 (20130101) A61N 1/3756 (20130101) Original (OR) Class A61N 1/3787 (20130101) A61N 1/37288 (20130101) A61N 1/37512 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911710 | Lu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University Of Cincinnati (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio) |
| INVENTOR(S) | Mingming Lu (Mason, Ohio) |
| ABSTRACT | A method of forming a yellow grease is provided. The method includes delivering a FOG lipid extraction agent into a processing tank. The method further includes preheating a waste grease to a temperature of between 35° C. and 95° C. The method further includes mixing the preheated waste grease with the FOG lipid extraction agent in the processing tank to form the yellow grease. |
| FILED | Monday, June 13, 2022 |
| APPL NO | 17/806613 |
| ART UNIT | 1799 — Selective Visual Display Systems |
| CURRENT CPC | Separation B01D 11/0457 (20130101) Original (OR) Class B01D 11/0492 (20130101) B01D 2221/06 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 88/26 (20130101) Producing, e.g by Pressing Raw Materials or by Extraction From Waste Materials, Refining or Preserving Fats, Fatty Substances, e.g Lanolin, Fatty Oils or Waxes; Essential Oils; Perfumes C11B 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911751 | Stanley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | George Geoffrey Stanley (Baton Rouge, Louisiana); Drew Michael Hood (Baton Rouge, Louisiana) |
| ABSTRACT | Disclosed are highly active cationic cobalt phosphine complexes, both mono- and bimetallic, that can catalyze hydroformylation reactions. The disclosed catalysts can be utilized in methods that provide reaction processes that are hundreds of times faster than high pressure HCo(CO)4 or phosphine-modified HCo(CO)3(PR3) catalysts and operate at considerably lower pressures and temperatures. Also disclosed are methods of hydroformylation using the described transition metal complexes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Tuesday, December 27, 2022 |
| APPL NO | 18/089365 |
| ART UNIT | 1738 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2409 (20130101) Original (OR) Class B01J 2231/321 (20130101) B01J 2531/0216 (20130101) B01J 2531/845 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911996 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Cardinal CG Company (Eden Prairie, Minnesota) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Cardinal CG Company (Eden Prairie, Minnesota) |
| INVENTOR(S) | Kezi Cheng (Cambridge, Massachusetts); Aftab Hussain (Cambridge, Massachusetts); Keith Burrows (Mineral Point, Wisconsin); David Clarke (Cambridge, Massachusetts) |
| ABSTRACT | Methods and apparatus for modulating light using a tunable light modulation device. The tunable light modulation devices comprises an elastomer structure including at least one elastomer layer, a compliant electrode network of conducting fibers arranged on a first surface of the at least one elastomer layer, a patterned electric conductor arranged on a second surface of the at least one elastomer layer opposite the first surface. The patterned electric conductor includes a plurality of individually-addressable sections, and the compliant electrode network is configured to compress the at least one elastomer layer in the presence of an electric field between the compliant electrode network and one or more of the individually-addressable sections of the patterned electric conductor to produce a voltage-dependent roughening of the at least one elastomer layer. |
| FILED | Tuesday, January 29, 2019 |
| APPL NO | 16/965531 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 17/10 (20130101) Original (OR) Class B32B 17/063 (20130101) B32B 25/08 (20130101) B32B 25/10 (20130101) B32B 2307/412 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/24 (20130101) E06B 2009/2405 (20130101) E06B 2009/2417 (20130101) E06B 2009/2464 (20130101) E06B 2009/2482 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/17 (20130101) G02F 2201/12 (20130101) G02F 2202/36 (20130101) G02F 2203/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911999 | Singamaneni et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Srikanth Singamaneni (St. Louis, Missouri); Jingyi Luan (St. Louis, Missouri); Jeremiah Morrissey (St. Louis, Missouri); Evan Kharasch (St. Louis, Missouri) |
| ABSTRACT | Fluorescence-based techniques are the cornerstone of modern biomedical optics with applications ranging from bioimaging at various scales (organelle to organism) to detection and quantification of a wide variety of biological species of interest. However, feeble fluorescence signal remains a persistent challenge in meeting the ever-increasing demand to image, detect and quantify biological species of low abundance. Disclosed herein are simple and universal methods based on a flexible and conformal elastomeric film adsorbed with plasmonic nanostructures, referred to as “plasmonic skin” or “plasmonic patch”, that provide large and uniform enhancement of fluorescence on a variety of surfaces, through an “add-on-top” process. The novel fluorescence enhancement approach presented here represents a disease-, biomarker-, and application-agnostic ubiquitously-applicable fundamental and enabling technology to improve the sensitivity of existing analytical methodologies in an easy-to-handle and cost-effective manner, without changing and/or minimally altering the original procedures of the existing techniques. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/662293 |
| ART UNIT | 1785 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/06 (20130101) Original (OR) Class B32B 2307/422 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912655 | Agrawal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Rakesh Agrawal (West Lafayette, Indiana); Yiru Li (West Lafayette, Indiana) |
| ABSTRACT | Processes and systems for upgrading natural gas liquids. At least a portion of the natural gas liquid components in a shale gas stream can be dehydrogenated to their corresponding olefin derivatives prior to separating any methane from the liquids. Further processing subsequent to dehydrogenation could include various separations, oligomerizing olefins produced in the dehydrogenation step, recovering desired products, etc. The order of the processing steps subsequent to dehydrogenation could be adjusted in various cases. |
| FILED | Wednesday, May 18, 2022 |
| APPL NO | 17/747637 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 2/06 (20130101) C07C 5/333 (20130101) Original (OR) Class C07C 11/02 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 5/00 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 3/102 (20130101) C10L 3/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912709 | Emrick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Todd Emrick (South Deerfield, Massachusetts); Matthew Skinner (Amherst, Massachusetts); Sarah M. Ward (Amherst, Massachusetts); Banishree Saha (Greenfield, Massachusetts) |
| ABSTRACT | A temozolomide compound according to formula (I) is described, wherein R1, L1, and X are defined herein. The temozolomide compound can be used to prepare polymers comprising temozolomide. Additionally, the polymers comprising temozolomide can be particularly useful in the treatment of certain diseases. |
| FILED | Monday, March 01, 2021 |
| APPL NO | 17/188162 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/787 (20130101) A61K 47/58 (20170801) A61K 47/60 (20170801) A61K 47/545 (20170801) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 22/10 (20130101) C08F 220/365 (20200201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912900 | Kulinsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Lawrence Kulinsky (Irvine, California); Tuo Zhou (Irvine, California) |
| ABSTRACT | Carbon nanotube (CNT) agglomerates can be aligned along the field lines between adjacent electrodes to form conductive bridges. The present invention is directed to a stepwise process of dielectrophoretic deposition of CNTs to form conducting bridges between adjacent electrodes spanning lengths over 50 microns. The CNT bridges are permanently secured using electrodeposition of the conducting polymer polypyrrole. Morphologies of the CNT bridges formed within a frequency range of 1 kHz and 10 MHz are employed and explained as a consequence of interplay between dielectrophoretic and electroosmotic forces. Postdeposition heat treatment increases conductivity of CNT bridges likely due to solvent evaporation and resulting surface tension inducing better contact between CNTs. |
| FILED | Tuesday, April 06, 2021 |
| APPL NO | 17/223459 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/4476 (20130101) Original (OR) Class Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 13/12 (20130101) C25D 13/22 (20130101) C25D 17/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913016 | Alexander et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | William Gerald Alexander (Madison, Wisconsin); David Peris Navarro (Madison, Wisconsin); Christopher Todd Hittinger (Madison, Wisconsin) |
| ABSTRACT | Methods of making synthetic yeast cells by mating together two diploid (or higher ploidy) yeast species or hybrids to generate multi-ploid yeast hybrids are provided herein. The synthetic yeast cells made by this process and kits for performing the process are also provided. |
| FILED | Tuesday, November 07, 2017 |
| APPL NO | 15/805950 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/18 (20130101) C12N 9/16 (20130101) C12N 15/65 (20130101) C12N 15/81 (20130101) C12N 15/905 (20130101) Original (OR) Class C12N 2800/80 (20130101) C12N 2840/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913701 | Goldfarbmuren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rebound Technologies, Inc. (Commerce City, Colorado) |
| ASSIGNEE(S) | Rebound Technologies, Inc. (Commerce City, Colorado) |
| INVENTOR(S) | Russell Goldfarbmuren (Denver, Colorado); Luke Erickson (Denver, Colorado); Josh Nelson (West Lafayette, Indiana); Chance Lord (Denver, Colorado) |
| ABSTRACT | Solid production systems, devices, and methods utilizing oleophilic surfaces are provided in accordance with various embodiments. Some embodiments include a water tank used to store fresh water. Some embodiments include an emulsion tank that may include a set of auxiliary components that may be utilized to create and/or to pump an emulsion. This auxiliary equipment may include suction headers, ejectors, pumps, mechanical mixers, and/or hydrodynamic mixers, for example. Some embodiments include a heat exchanger that may produce a cold surface for ice formation. This surface may include an oleophilic surface that may produce an affinity for oils and/or other non-polar materials. Some embodiments include piping that may allow for the connection of the other components such that ice may be formed from a flow of water from the emulsion and the overflow may be returned to the emulsion tank. Ice making methods are also provided. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/942297 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Producing, Working or Handling Ice F25C 1/04 (20130101) F25C 1/12 (20130101) Original (OR) Class F25C 5/187 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913827 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Qin Zhou (Fremont, California); Alexander K. Zettl (Kensington, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to an ultrasonic microphone and an ultrasonic acoustic radio. In one aspect a system includes a transmitter and a receiver. The receiver comprises a membrane. The membrane comprises a single layer or multiple layers of a two-dimensional material. The receiver is operable to receive sound waves in a frequency range, with the frequency range being the ultrasonic frequency range. |
| FILED | Wednesday, September 28, 2022 |
| APPL NO | 17/954728 |
| ART UNIT | 2653 — Videophones and Telephonic Communications |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 3/12 (20130101) G01H 11/06 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/104 (20130101) Electric Digital Data Processing G06F 3/0325 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 1/08 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 19/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913867 | Yanik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ahmet Ali Yanik (Santa Cruz, California); Xiangchao Zhu (Santa Cruz, California); Yixiang Li (Santa Cruz, California) |
| ABSTRACT | An optofluidic device includes: a housing having an inlet port coupled to an inlet side and an outlet port coupled to an outlet side; and a microlens disposed within the housing between the inlet side and the outlet side. A fluid having a plurality of particles flows from the inlet side through the microlens to the outlet side. The optofluidic device further includes a light source configured to emit a light beam in a direction opposite flow direction of the fluid, the light beam defining an optical axis that is perpendicular to the microlens. |
| FILED | Tuesday, June 14, 2022 |
| APPL NO | 17/839826 |
| ART UNIT | 3653 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1056 (20130101) Original (OR) Class G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) G01N 2015/1087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913872 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Darren Yang (Cambridge, Massachusetts); Andrew Ward (Boston, Massachusetts); Wesley Philip Wong (Cambridge, Massachusetts); Kenneth Anders Halvorsen (Glenmont, New York) |
| ABSTRACT | An apparatus for measuring a characteristic of a sample using a centrifuge and optical components is disclosed. The centrifuge may be a standard benchtop centrifuge. The optical components may be sized and dimensioned to fit, along with the sample, inside the centrifuge. |
| FILED | Thursday, February 04, 2021 |
| APPL NO | 17/167847 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Centrifuges B04B 13/00 (20130101) B04B 15/02 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/68 (20130101) C12Q 1/6816 (20130101) C12Q 2523/303 (20130101) C12Q 2525/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) G01N 21/07 (20130101) Original (OR) Class G01N 33/53 (20130101) G01N 33/543 (20130101) G01N 33/557 (20130101) G01N 2015/0038 (20130101) G01N 2015/0065 (20130101) G01N 2015/1006 (20130101) G01N 2201/021 (20130101) G01N 2201/0423 (20130101) G01N 2201/0693 (20130101) G01N 2203/0089 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913939 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Amberstone Biosciences, Inc. (Laguna Hills, California) |
| ASSIGNEE(S) | Amberstone Biosciences, Inc. (Laguna Hills, California) |
| INVENTOR(S) | George Guikai Wu (Laguna Hills, California); Yonglei Shang (Laguna Hills, California) |
| ABSTRACT | Methods and systems for performing assays in compartmentalized nano-volumes to screen for functional bispecific or multispecific biologics, including: providing a plurality of at least two distinct types of cells, wherein two or more first-type cells are engineered to express substantially a single genetic-variant per cell for a bispecific or multispecific biologic in a secreted form, wherein two or more second-type cells are selected or engineered to produce a positive reporter molecule signal that is triggered by a functional variant of the said biologic expressed by a first-type cell; providing a plurality of compartmentalized nano-volumes, wherein two or more nano-volumes are each provided with substantially one first-type cell, and one or more second-type cell(s); incubating the said nano-volumes over a period of time to allow the expression and secretion of the said biologics inside the said nano-volumes; collecting data representing the positive reporter molecule signal triggered by secreted biologics inside the said nano-volumes, and recovering cells from the nano-volumes with the positive reporter molecule signal and extracting the genetic information representing respective functional variants of the biologics. |
| FILED | Friday, April 02, 2021 |
| APPL NO | 17/221688 |
| ART UNIT | 1678 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11915105 | Steingrimsson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baldur Andrew Steingrimsson (Hillsboro, Oregon) |
| ASSIGNEE(S) | IMAGARS LLC (Wilsonville, Oregon) |
| INVENTOR(S) | Baldur Andrew Steingrimsson (Hillsboro, Oregon); Peter K Liaw (Knoxville, Tennessee); Xuesong Fan (Knoxville, Tennessee); Anand A Kulkarni (Charlotte, North Carolina); Duckbong Kim (Cookeville, Tennessee) |
| ABSTRACT | This invention presents an innovative framework for the application of machine learning for identification of alloys or composites with desired properties of interest. For each output property of interest, we identify the corresponding driving (input) factors. These input factors may include the material composition, heat treatment, process, microstructure, temperature, strain rate, environment or testing mode. Our framework assumes selection of optimization technique suitable for the application at hand and data available, starting with simple linear, or quadratic, regression analysis. We present a physics-based model for predicting the ultimate tensile strength, a model that accounts for physical dependencies, and factors in the underlying physics as a priori information. In case an artificial neural network is deemed suitable, we suggest employing custom kernel functions consistent with the underlying physics, for the purpose of attaining tighter coupling, better prediction, and extracting the most out of the—usually limited—input data available. |
| FILED | Wednesday, February 05, 2020 |
| APPL NO | 16/782829 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/22 (20210101) B22F 10/25 (20210101) B22F 10/28 (20210101) B22F 10/36 (20210101) B22F 10/80 (20210101) B22F 10/85 (20210101) B22F 10/366 (20210101) B22F 10/368 (20210101) B22F 12/45 (20210101) B22F 12/90 (20210101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) B29C 64/268 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 70/10 (20200101) Electric Digital Data Processing G06F 18/211 (20230101) G06F 18/213 (20230101) G06F 30/27 (20200101) G06F 2113/10 (20200101) G06F 2119/08 (20200101) Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) G06N 20/00 (20190101) Original (OR) Class Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/30 (20190201) G16C 20/70 (20190201) G16C 60/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11915837 | Graves et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf Of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | William Graves (Tempe, Arizona); Lucas Malin (Tempe, Arizona) |
| ABSTRACT | A method includes simulating diffraction in a transmission geometry of relativistic electron bunches from a crystallographic structure of a crystal thereby simulating diffraction of the relativistic electron bunches into a plurality of Bragg peaks. The method includes selecting a range of angles between a direction of propagation of the relativistic electron bunches and a normal direction of crystal including an angle at which a diffraction portion is maximized. The method includes sequentially accelerating a plurality of physical electron bunches to relativistic energies toward a physical crystal having the crystallographic structure and diffracting the plurality of physical electron bunches off the physical crystal at different angles and measuring the diffraction portion into the respective Bragg peak at the different angles. The method includes selecting a final angle based on the measured diffraction portion into the respective Bragg peak at the different angles and generating a pulse of light. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 17/378094 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20008 (20130101) G01N 2223/102 (20130101) G01N 2223/0565 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/062 (20130101) Original (OR) Class G21K 2201/061 (20130101) G21K 2201/067 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 4/00 (20130101) X-ray Technique H05G 2/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916162 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wright State University (Dayton, Ohio) |
| ASSIGNEE(S) | Wright State University (Dayton, Ohio) |
| INVENTOR(S) | Elliott R. Brown (Beavercreek, Ohio); Weidong Zhang (Cary, North Carolina); Tyler Growden (Dublin, Ohio); Paul Berger (Columbus, Ohio) |
| ABSTRACT | A unipolar-doped light emitting diode or laser diode is described. The diode includes a bottom region having an n-type layer, a top region having an n-type layer, and a middle region between the top and bottom regions having at least one material different from the top or bottom region forming two or more heterojunctions. The top and bottom regions create light emission by interband tunneling-induced photon emission. Systems including the unipolar-doped diode including LIDAR are also taught. |
| FILED | Wednesday, October 28, 2020 |
| APPL NO | 17/083286 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4815 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/15 (20130101) H01L 33/06 (20130101) H01L 33/0025 (20130101) Original (OR) Class H01L 33/0029 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/347 (20130101) H01S 5/0657 (20130101) H01S 5/3095 (20130101) H01S 5/34313 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916234 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); David Lam (Chicago, Illinois); Kan-Sheng Chen (Chicago, Illinois); Joohoon Kang (Evanston, Illinois) |
| ABSTRACT | Anhydrous liquid-phase exfoliation of germanium sulfide to provide few-layer germanium sulfide, as can be incorporated into electronic devices such as but not limited to batteries and cells comprising such materials. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/755680 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 17/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/77 (20130101) C01P 2002/82 (20130101) C01P 2002/84 (20130101) C01P 2002/85 (20130101) C01P 2004/04 (20130101) C01P 2004/24 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/5815 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916511 | Atcitty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Urban Electric Power (Pearl River, New York); Arrowhead Center, Inc. (Las Cruces, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia (Albuquerque, New Mexico); Arrowhead Center, Inc. (Las Cruces, New Mexico); Valerio De Angelis (Santa Barbara, California) |
| INVENTOR(S) | Stanley Atcitty (Albuquerque, New Mexico); Valerio De Angelis (Santa Barbara, California); Satishkumar J. Ranade (Las Cruces, New Mexico); Sijo Augustine (Las Cruces, New Mexico); Nataraj Pragallapati (Edison, New Jersey); Olga Lavrova (Las Cruces, New Mexico) |
| ABSTRACT | A DC bus is connected to a PV array, a battery or both, to power a grid connected inverter load on the bus. A system and method is described for controlling current flow on a DC bus regardless of the type of inverter. A converter receives a DC battery voltage. A switching module controls current flow through the converter. A current generator generates a reference current in response to a reference voltage. A comparator connected at the output of the current generator compares the reference current with a battery current and outputs a signal to a controller. The controller generates a reference value. A PWM generator modulates the switch module to control current flow and energy flow between the DC bus and the battery. The current from the DC bus to the inverter is controlled to allow proper grid-connected operation regardless of inverter type. |
| FILED | Wednesday, October 13, 2021 |
| APPL NO | 17/500632 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0068 (20130101) H02J 2300/26 (20200101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/32 (20141201) Original (OR) Class H02S 40/38 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11916866 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Lu Cheng (Tempe, Arizona); Kai Shu (Mesa, Arizona); Siqi Wu (Canberra, Australia); Yasin Silva (Glendale, Arizona); Deborah Hall (Phoenix, Arizona); Huan Liu (Tempe, Arizona) |
| ABSTRACT | A computer-implemented framework and/or system for cyberbullying detection is disclosed. The system includes two main components: (1) A representation learning network that encodes the social media session by exploiting multi-modal features, e.g., text, network, and time; and (2) a multi-task learning network that simultaneously fits the comment inter-arrival times and estimates the bullying likelihood based on a Gaussian Mixture Model. The system jointly optimizes the parameters of both components to overcome the shortcomings of decoupled training. The system includes an unsupervised cyberbullying detection model that not only experimentally outperforms the state-of-the-art unsupervised models, but also achieves competitive performance compared to supervised models. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 17/546648 |
| ART UNIT | 2441 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 40/30 (20200101) Computer Systems Based on Specific Computational Models G06N 3/088 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 51/52 (20220501) Original (OR) Class H04L 51/212 (20220501) H04L 67/535 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11917337 | Shreve et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | XEROX CORPORATION (Norwalk, Connecticut) |
| INVENTOR(S) | Matthew A. Shreve (Webster, New York); Eric Cocker (Redwood City, California) |
| ABSTRACT | The present specification relates to image capture. More specifically, it relates to selective image capture for sensor carrying devices or floats deployed, for example, on the open sea. In one form, data is generated on the sensor carrying devices or floats by an on-board Inertial Measurement Unit (IMU) and is used to automatically predict the wave motion of the sea. These predictions are then used to determine an acceptable set of motion parameters that are used to trigger the on-board camera(s). The camera(s) then capture images. One consideration is that images captured at or near the peak of a wave crest with minimal pitch and roll will contain fewer obstructions (such as other waves). Such images provide a view further into the horizon to, for example, monitor maritime sea traffic and other phenomenon. Therefore, the likelihood of capturing interesting objects such as ships, boats, garbage, birds, . . . etc. is increased. These images may then be further processed and/or transmitted in a variety of manners. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 17/463433 |
| ART UNIT | 2426 — Cable and Television |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 79/15 (20200101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 13/004 (20130101) Pictorial Communication, e.g Television H04N 7/188 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11911441 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ONCOIMMUNE, INC. (Rockville, Maryland); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | ONCOIMMUNE, INC. (Rockville, Maryland); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Yang Liu (Baltimore, Maryland); Pan Zheng (Baltimore, Maryland); Martin Devenport (Gaithersburg, Maryland) |
| ABSTRACT | The present invention relates to the use of a CD24 protein for preventing or treating relapse of a cancer in a subject. The present invention also relates to the use of a CD24 protein for reducing cancer stem cell activity. |
| FILED | Monday, June 03, 2019 |
| APPL NO | 15/734957 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/02 (20130101) A61K 38/177 (20130101) Original (OR) Class A61K 39/001129 (20180801) A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/04 (20180101) A61P 37/06 (20180101) Peptides C07K 14/70596 (20130101) C07K 16/4241 (20130101) C07K 2317/41 (20130101) C07K 2317/53 (20130101) C07K 2317/524 (20130101) C07K 2317/526 (20130101) C07K 2317/528 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911444 | Comer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Stratatech Corporation (Madison, Wisconsin) |
| ASSIGNEE(S) | Stratatech Corporation (Madison, Wisconsin) |
| INVENTOR(S) | Allen R. Comer (Madison, Wisconsin); B. Lynn Allen-Hoffmann (Madison, Wisconsin) |
| ABSTRACT | The present invention relates generally to compositions for treating patients that have skin cancer or have recently had skin cancers removed. More specifically, the present invention provides human skin substitutes engineered to express exogenous IL-12 and compositions and methods for making human skin substitutes engineered to express exogenous IL-12. In addition, the present invention provides methods for treatment of sites on a patient where skin cancers have been removed with human skin substitutes engineered to express exogenous IL-12. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/150048 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 38/208 (20130101) Original (OR) Class A61K 48/00 (20130101) Peptides C07K 14/5434 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0629 (20130101) C12N 2501/23 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912702 | Fuller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alkermes, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Alkermes, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Nathan Oliver Fuller (Arlington, Massachusetts); John A. Lowe, III (Stonington, Connecticut) |
| ABSTRACT | Provided herein are compounds and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of conditions associated with inhibition of HDAC (e.g,. HDAC2). |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 17/558840 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 487/04 (20130101) C07D 513/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913052 | Jewett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Ashty Stephen Karim (Chicago, Illinois); Jian Li (Evanston, Illinois); Quentin Dudley (Evanston, Illinois) |
| ABSTRACT | Disclosed are cell-free systems for metabolic engineering, methods for cell-free metabolic engineering, kits for preparing the disclosed systems, and kits for performing the disclosed methods. The disclosed systems, methods, and kits may be utilized to prepare a chemical product or natural product and to optimize conditions for preparing a chemical product or natural product. The disclosed systems, methods, and kits also may be utilized for combinatorial cell-free metabolism engineering. |
| FILED | Monday, March 02, 2020 |
| APPL NO | 16/807147 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913939 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Amberstone Biosciences, Inc. (Laguna Hills, California) |
| ASSIGNEE(S) | Amberstone Biosciences, Inc. (Laguna Hills, California) |
| INVENTOR(S) | George Guikai Wu (Laguna Hills, California); Yonglei Shang (Laguna Hills, California) |
| ABSTRACT | Methods and systems for performing assays in compartmentalized nano-volumes to screen for functional bispecific or multispecific biologics, including: providing a plurality of at least two distinct types of cells, wherein two or more first-type cells are engineered to express substantially a single genetic-variant per cell for a bispecific or multispecific biologic in a secreted form, wherein two or more second-type cells are selected or engineered to produce a positive reporter molecule signal that is triggered by a functional variant of the said biologic expressed by a first-type cell; providing a plurality of compartmentalized nano-volumes, wherein two or more nano-volumes are each provided with substantially one first-type cell, and one or more second-type cell(s); incubating the said nano-volumes over a period of time to allow the expression and secretion of the said biologics inside the said nano-volumes; collecting data representing the positive reporter molecule signal triggered by secreted biologics inside the said nano-volumes, and recovering cells from the nano-volumes with the positive reporter molecule signal and extracting the genetic information representing respective functional variants of the biologics. |
| FILED | Friday, April 02, 2021 |
| APPL NO | 17/221688 |
| ART UNIT | 1678 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914042 | Schaefer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Philip Raymond Schaefer (Weaverville, North Carolina) |
| ASSIGNEE(S) | Vortant Technologies, LLC (Weaverville, North Carolina) |
| INVENTOR(S) | Philip Raymond Schaefer (Weaverville, North Carolina) |
| ABSTRACT | A system shines a series of light stripes across an area. A target object passes through the area and light is reflected to the system from the light stripes as it passes through. Based on the timing of the received light from each of the light stripes, the system calculates the position and velocity of the target object. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/506608 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/68 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11911392 | Shapiro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Paul S. Shapiro (Baltimore, Maryland); Alexander D. Mackerell, Jr. (Baltimore, Maryland); Jeffrey D. Hasday (Timonium, Maryland) |
| ABSTRACT | Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/740248 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/54 (20130101) A61K 31/5375 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) A61P 29/00 (20180101) A61P 31/00 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911393 | Shapiro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland); The United States of America as represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Paul S. Shapiro (Baltimore, Maryland); Alexander D. Mackerell, Jr. (Baltimore, Maryland); Jeffrey D. Hasday (Timonium, Maryland) |
| ABSTRACT | Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases. |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/169785 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/54 (20130101) A61K 31/5375 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) A61P 29/00 (20180101) A61P 31/00 (20180101) A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911481 | Markoutsa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Eleni Markoutsa (Tampa, Florida); Subhra Mohapatra (Tampa, Florida); Shyam Mohapatra (Tampa, Florida) |
| ABSTRACT | This invention provides for a RSV-targeted nanoparticle PMN (RTPMN), combining HR2D anti-fusion peptide, and plasmid encoded siRNA against RSV-NS1 and/or RSV-P gene as a safe, effective and inexpensive anti-RSV prophylaxis and/or therapy. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 17/057153 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 45/06 (20130101) A61K 47/544 (20170801) Original (OR) Class A61K 47/6939 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1131 (20130101) C12N 2310/14 (20130101) C12N 2310/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11911487 | Bacallao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Bloomington, Indiana); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Robert Bacallao (Indianapolis, Indiana); Simon Atkinson (Carmel, Indiana); George Rhodes (Fishers, Indiana); Peter Corridon (Indianapolis, Indiana) |
| ABSTRACT | The present invention provides methods and materials useful delivering liquids, including liquids comprising nucleic acid molecules into cells. In particular, the present invention provides methods for delivering saline solution, exogenous compositions, and isolated vectors to kidney cells, using the renal vein as a guide and under hydrodynamic pressure. The delivery methods and materials herein are useful to research, prognose, ameliorate symptoms of kidney injury, and treat kidney pathologies. |
| FILED | Friday, May 03, 2013 |
| APPL NO | 14/398697 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/45 (20130101) A61K 38/443 (20130101) A61K 48/0058 (20130101) A61K 48/0075 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10041 (20130101) Enzymes C12Y 101/01042 (20130101) C12Y 208/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912998 | Wyss-Coray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Anton Wyss-Coray (Palo Alto, California); Thomas A. Rando (Stanford, California); Markus Britschgi (Allscwil, Switzerland); Kaspar Rufibach (Basel, Switzerland); Saul A. Villeda (Lancaster, California) |
| ABSTRACT | Methods of treating an adult mammal for an aging-associated impairment are provided. Aspects of the methods include modulating CCR3, e.g., by modulating eotaxin-1/CCR3 interaction, in the mammal in a manner sufficient to treat the mammal for the aging-associated impairment. A variety of aging-associated impairments may be treated by practice of the methods, which impairments include cognitive impairments. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/550787 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/7088 (20130101) A61K 38/19 (20130101) A61K 38/45 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/24 (20130101) C07K 16/28 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2799/06 (20130101) C12N 2799/022 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 207/10001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11911717 | Arthur et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FREMONTA Corporation (San Jose, California); The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | Fremonta Corporation (San Jose, California) |
| INVENTOR(S) | Terrance Arthur (Hastings, Nebraska); Tommy Wheeler (Clay Center, Nebraska); Eric Child Wilhelmsen (Milpitas, California); Florence Q. Wu (Milpitas, California); Yongqing Huang (Newark, California); Wei Wu (Fremont, California) |
| ABSTRACT | Certain aspects of the present disclosure relate to methods and apparatus for microbial sampling of foods. For example, a method may include providing at least one aggregating sampler at one or more sampling locations, and sampling a production lot of produce or other food items such as meat using the at least one aggregating sampler to create one or more samples that makes up a microbial sampling. Certain aspects of the present disclosure relate to methods and apparatus for microbial sampling of foods. For example, an apparatus, such as a microbial aggregating sampler, may include a covering having a microbial sampling material with a pocket formed in the covering to receive an appendage or a tool for handling of the covering. |
| FILED | Monday, July 29, 2019 |
| APPL NO | 16/525350 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Separation B01D 21/262 (20130101) Original (OR) Class B01D 61/025 (20130101) B01D 61/145 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6888 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) G01N 1/4077 (20130101) G01N 33/02 (20130101) G01N 2001/4088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912805 | Cochran et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| INVENTOR(S) | Eric W. Cochran (Ames, Iowa); Xianglan Bai (Ames, Iowa); Wangda Qu (Ames, Iowa); Yuerui Huang (Ames, Iowa); Yixin Luo (Ames, Iowa) |
| ABSTRACT | One aspect of the present application relates to a method of synthesizing a thermoplastic polymer. This method includes providing a depolymerized lignin product comprising monomers and oligomers and producing lignin (meth)acrylate monomers and oligomers from the depolymerized lignin product. A thermoplastic lignin (meth)acrylate polymer is then formed by free radical polymerization of the lignin (meth)acrylate monomers and oligomers. The present application also relates to a branched chain thermoplastic lignin (meth)acrylate polymer which includes a chain transfer agent. The thermoplastic lignin based polymers of the present application can be used to prepare carbon fibers, and engineering thermoplastics. Mixtures of lignin (meth)acrylate monomers and oligomers are also disclosed. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 16/779018 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/05 (20170801) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 293/005 (20130101) Original (OR) Class C08F 2438/01 (20130101) C08F 2438/03 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/12 (20130101) C08J 2397/02 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) D01F 11/122 (20130101) D01F 11/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11912894 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Minglin Ma (Ithaca, New York); You Yong (Ithaca, New York); Mingyu Qiao (Ithaca, New York); Qingsheng Liu (Ithaca, New York) |
| ABSTRACT | The present application discloses a method of forming a hydrogel-coated substrate, wherein the hydrogel has antifouling and antimicrobial properties. The method comprises applying an aqueous pre-hydrogel solution to a substrate, polymerizing the aqueous pre-hydrogel solution, thereby forming a coated substrate having a conformal hydrogel coating and a non-conformal hydrogel coating, contacting the coated substrate with a swelling agent, and removing the non-conformal hydrogel coating from the coated substrate, thereby leaving the conformal hydrogel coating on the substrate to form the hydrogel-coated substrate. The aqueous pre-hydrogel solution comprises a monomer with antimicrobial activity, a monomer with antifouling activity, and either a polymer, oligomer, or macromer which, when polymerized together, form a hydrogel. Also disclosed is a coated substrate and a hydrogel coating. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 16/696469 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/60 (20130101) A61L 17/005 (20130101) A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 29/145 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 3/067 (20130101) B05D 3/101 (20130101) B05D 3/108 (20130101) B05D 2201/02 (20130101) B05D 2320/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/1625 (20130101) Original (OR) Class C09D 5/1662 (20130101) C09D 5/1687 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11913933 | Dong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Liang Dong (Ames, Iowa); Md. Azahar Ali (Ames, Iowa); Xinran Wang (Ames, Iowa); Michael Castellano (Ames, Iowa) |
| ABSTRACT | Apparatus, methods, and systems for transducing measurements from medium of interest. One non-limiting example is in planta monitoring of plants. In one aspect, a micro- or nano-scale probe body includes one or more microprobes (e.g. microneedles or waveguides) to access desired plant tissue, and one or more microsensors on the probe body. A microcircuit on or in the probe body transduces relevant measurements from the microsensor(s). An output interface allows storage, communication, or transfer of the transduced measurement for further use. Non-limiting examples are processing into estimations of chemical concentrations or the like for biochemical sensing. As such, if used as in planta sensors, they can be minimally invasive and cost effective for both single use and use in sets for plural plants with one central station. |
| FILED | Monday, December 28, 2020 |
| APPL NO | 17/247857 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Planting; Sowing; Fertilising A01C 1/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 33/0098 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11912078 | Creager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Colin M. Creager (Cleveland, Ohio); Santo A. Padula, II (Cleveland, Ohio); Calvin Young (Cleveland, Ohio) |
| ABSTRACT | The innovation presented herein provides among its embodiments, a non-pneumatic structure such as a vehicle tire, consisting of a matrix of shape memory alloy (SMA) elements. The interlocking layering pattern provides geometries which leverage the SMA material properties to accomplish performance characteristics of traditional pneumatic structures across a spectrum of possible desired uses including normal personal use, recreational use, sport use and commercial use. Embodiments include applying structural design and material properties to provide a fixed or a variable set of performance characteristics. Similar to the fruits of other space program initiatives, the innovation leverages material science developed for extra-terrestrial purposes to accomplish advances over conventional items. |
| FILED | Friday, December 11, 2020 |
| APPL NO | 17/119632 |
| ART UNIT | 3617 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Vehicle Tyres Tyre Inflation; Tyre Changing or Repairing; Repairing, or Connecting Valves To, Inflatable Elastic Bodies in General; Devices or Arrangements Related to Tyres B60C 7/06 (20130101) Original (OR) Class B60C 7/14 (20130101) B60C 2200/12 (20130101) Alloys C22C 19/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11915602 | Ozturk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Ender Ozturk (Raleigh, North Carolina); Fatih Erden (Raleigh, North Carolina); Haluk Celebi (Raleigh, North Carolina); Ismail Guvenc (Raleigh, North Carolina); Ozgur Ozdemir (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure describes various embodiments of systems and methods of detecting, classifying, and making a threat assessment of an unmanned aerial vehicle (UAV). One such method comprises detecting a radio frequency (RF) signal; determining that the RF signal is generated from an unmanned aerial vehicle (UAV) based on the detected RF signal; classifying at least a make and model of the UAV based on the detected RF signal; sensing for a remote identification field data broadcasted by the UAV; receiving remote identification information of the UAV from a network database, if the network database is available; assessing a threat likelihood of the UAV based on joint processing of at least the RF signal based classification of the UAV and the received remote identification information of the UAV; and signaling an alert containing a description of the UAV and the threat if the UAV is assessed as a harmful threat. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/387140 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/412 (20130101) Electric Digital Data Processing G06F 18/214 (20230101) Traffic Control Systems G08G 5/0013 (20130101) G08G 5/0069 (20130101) G08G 5/0082 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11911799 | Coupar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | George Coupar (Leesburg, Virginia); Jeffrey A. Fox (Alexandria, Virginia); James Whipple (Greenbelt, Maryland); Gabriel Difurio (Stevenson, Virginia) |
| ABSTRACT | A system and method for enhanced monitoring and sorting of delivery items, such as packages, which are moved and sorted via a delivery service conveyor device. Conventional systems may employ photocells, which detect interrupted light beams, to identify packages or delivery items along a conveyor path. The present system and method enhances photocell function by adding image detection and analysis to the mail path; and further by modifying the photocell signals to the sorter/conveyor control. The present sensing system is located in the same area on the transport as the photocell, and uses a camera to capture an image of the mail path in the photocell area. The system and method then analyze a package image to formulate a more accurate item detection signal, based on photocell data and image data, for input to the sorter/conveyor control system. |
| FILED | Monday, March 13, 2023 |
| APPL NO | 18/182680 |
| ART UNIT | 3655 — Material and Article Handling |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/12 (20130101) B07C 3/14 (20130101) Original (OR) Class Machines, Apparatus or Devices For, or Methods Of, Packaging Articles or Materials; Unpacking B65B 57/12 (20130101) Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 43/08 (20130101) B65G 2201/0285 (20130101) B65G 2203/041 (20130101) B65G 2203/044 (20130101) B65G 2203/0208 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11914354 | Shiu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Leung Man Shiu (Gaithersburg, Maryland); Erich Joseph Petre (Gainesville, Virginia) |
| ABSTRACT | Systems and methods for commanding, controlling, and guiding automated guided vehicles (“AGVs”). Automated systems translate AGV commands according to AGV manufacturers. AGVs can be summoned and destinations be determined automatically. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 17/805414 |
| ART UNIT | 3655 — Material and Article Handling |
| CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 1/1371 (20130101) B65G 1/1378 (20130101) B65G 2203/041 (20130101) B65G 2203/042 (20130101) Hoisting, Lifting, Hauling or Pushing, Not Otherwise Provided For, e.g Devices Which Apply a Lifting or Pushing Force Directly to the Surface of a Load B66F 9/063 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/04 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/41895 (20130101) Original (OR) Class G05B 2219/40298 (20130101) G05B 2219/45063 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 2201/0216 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 11911308 | Thorpe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Crown in right of the State of New South Wales acting through the Department of Justice Corrective Services NSW, Corrective Services Industries (Sydney, Australia) |
| ASSIGNEE(S) | The Crown in right of the State of New South Wales acting through the Department of Justice Corrective Services NSW, Corrective Services Industries (Sydney, Australia) |
| INVENTOR(S) | Stephen John Thorpe (Sydney, Australia); Kevin Desmond Corcoran (Sydney, Australia); Derek Brindle (Sydney, Australia); George Semertzidis (Victoria, Australia) |
| ABSTRACT | A non-injurious restraint for securing a person to an object comprising a flexible strap comprised of, or including a substantially cut-resistant webbing associated with a strip of steel interlinked rings and reinforcement cables. A locking mechanism including one or more projections or pins adapted to engage the interlinked rings in forming a fixed length loop. The strap adapted to be secured to the object with the loop adjusted to encircle the limb, and wherein the locking mechanism locks the length of the loop. A webbing for use in such restraints. |
| FILED | Thursday, August 17, 2017 |
| APPL NO | 16/325794 |
| ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/3723 (20130101) Original (OR) Class A61F 5/3761 (20130101) Locks; Accessories Therefor; Handcuffs E05B 75/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 11911313 | Brockman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brockman-Hastings LLC (Lexington, Kentucky) |
| ASSIGNEE(S) | Brockman-Hastings LLC (Lexington, Kentucky) |
| INVENTOR(S) | Edward Britt Brockman (Louisville, Kentucky); Jeffrey Todd Hastings (Lexington, Kentucky); Carlos Andres Jarro (Lexington, Kentucky); James L. Russell (Lexington, Kentucky) |
| ABSTRACT | An eye implantation device has a body including a support system adapted to engage at three points with an iridocorneal angle of an anterior chamber of an eye into which the device is implanted. |
| FILED | Thursday, December 31, 2020 |
| APPL NO | 17/139205 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/02 (20130101) A61B 3/16 (20130101) A61B 5/6821 (20130101) A61B 5/6839 (20130101) A61B 5/6882 (20130101) A61B 5/14503 (20130101) A61B 5/14546 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11912437 | Grizzle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Tewksbury, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Tewksbury, Massachusetts) |
| INVENTOR(S) | James B. Grizzle (Oro Valley, Arizona); Tanner P. Reznicek (Aurora, Colorado); Cory M. Polivchak (Tucson, Arizona) |
| ABSTRACT | A universal payload manipulation tool employs a segmented ring captured in a telescoping cradle to perform the positioning functions of both a workstation and a loading adapter. The ring rotates over a range of 360 degrees to perform the position functions of the workstation. With the upper ring segment removed, the telescoping cradle rotates and the lower ring segment rotates and extends from the telescoping cradle over a combined range of rotation to position the payload at a specified angle for unloading to perform the position functions of a loading adapter. This configuration allows the universal tool to access confined spaces while supporting a range of rotation required in many applications for unloading the payload (loading the payload to another platform such as an aircraft). The manipulation tool may also be configured as only a loading adapter. |
| FILED | Wednesday, November 04, 2020 |
| APPL NO | 17/089475 |
| ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/32 (20130101) Original (OR) Class Hoisting, Lifting, Hauling or Pushing, Not Otherwise Provided For, e.g Devices Which Apply a Lifting or Pushing Force Directly to the Surface of a Load B66F 9/16 (20130101) B66F 9/184 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11915435 | Boroughs |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Tewksbury, Massachusetts) |
| INVENTOR(S) | Grant B. Boroughs (Southlake, Texas) |
| ABSTRACT | A computer-implemented system and method of image cross-correlation improves the sub-pixel accuracy of the correlation surface and subsequent processing thereof. One or both of the template or search windows are resampled using the fractional portions of the correlation offsets X and Y produced by the initial image cross-correlation. The resampled window is then correlated with the other original window to produce a resampled cross-correlation surface. Removing the fractional or sub-pixel offsets between the template and search windows improves the “sameness” of the represented imagery thereby improving the quality and accuracy of the correlation surface, which in turn improves the quality and accuracy of the FOM or other processing of the correlation surface. The process may be iterated to improve accuracy or modified to generate resampled cross-correlation surfaces for multiple possible offsets and to accept the one with the most certainty. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 17/378113 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/32 (20170101) Original (OR) Class G06T 7/38 (20170101) G06T 7/215 (20170101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 27, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
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FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240227.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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