FedInvent™ Patents

Patent Details for Tuesday, March 19, 2024 

This page was updated on Tuesday, March 19, 2024 at 04:34 PM GMT

Department of Health and Human Services (HHS) 

US 11931116 Krishnaswamy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Venkataramanan Krishnaswamy (Lebanon, New Hampshire);  Richard J. Barth, Jr. (Hanover, New Hampshire);  Keith D. Paulsen (Hanover, New Hampshire)
ABSTRACT A method for guiding resection of local tissue from a patient includes generating at least one image of the patient, automatically determining a plurality of surgical guidance cues indicating three-dimensional spatial properties associated with the local tissue, and generating a visualization of the surgical guidance cues relative to the surface. A system for generating surgical guidance cues for resection of a local tissue from a patient includes a location module for processing at least one image of the patient to determine three-dimensional spatial properties of the local tissue, and a surgical cue generator for generating the surgical guidance cues based upon the three-dimensional spatial properties. A patient-specific locator form for guiding resection of local tissue from a patient includes a locator form surface matching surface of the patient, and a plurality of features indicating a plurality of surgical guidance cues, respectively.
FILED Monday, July 25, 2022
APPL NO 17/872606
ART UNIT 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/10 (20160201)
A61B 34/20 (20160201) Original (OR) Class
A61B 34/25 (20160201)
A61B 90/361 (20160201)
A61B 2017/008 (20130101)
A61B 2017/3405 (20130101)
A61B 2034/105 (20160201)
A61B 2034/107 (20160201)
A61B 2034/2065 (20160201)
A61B 2090/365 (20160201)
A61B 2090/378 (20160201)
A61B 2090/395 (20160201)
A61B 2090/3908 (20160201)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 7/33 (20170101)
G06T 2207/30068 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931163 Perelman
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Lev T. Perelman (Brookline, Massachusetts)
ABSTRACT Described herein are embodiments of an approach to diagnosing pancreatic cystic lesions using light scattering spectroscopy. In some embodiments, the approach includes an apparatus including a spatial gating probe to isolate light reflected by the epithelial tissue of the internal cyst surface using spatial gating. In some further embodiments, the apparatus includes a scanning fiber probe that is capable of rotational and linear motion in order to scan the entire internal surface of the cyst. Use of such an approach may be advantageous to improve the accuracy of diagnosing pancreatic cystic lesions as cancerous, precancerous, or benign.
FILED Friday, February 23, 2018
APPL NO 16/487768
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0075 (20130101)
A61B 5/0084 (20130101)
A61B 5/425 (20130101) Original (OR) Class
A61B 8/0841 (20130101)
A61B 10/0045 (20130101)
A61B 2010/0061 (20130101)
A61B 2562/0242 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931339 Stamler
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio);  UNIVERSITY HOSPITALS CLEVELAND MEDICAL CENTER (Cleveland, Ohio)
INVENTOR(S) Jonathan S. Stamler (Cleveland, Ohio)
ABSTRACT A method for preventing or treating a tissue injury and/or promoting tissue repair in a subject in need thereof, includes administering to the subject a therapeutically effective amount of an ADH inhibitor, AKR inhibitor, SCoR inhibitor, and/or PKM2 inhibitor.
FILED Tuesday, June 25, 2019
APPL NO 17/256066
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/422 (20130101)
A61K 31/424 (20130101)
A61K 31/497 (20130101)
A61K 31/506 (20130101)
A61K 31/4166 (20130101) Original (OR) Class
A61K 31/4178 (20130101)
A61K 31/4439 (20130101)
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931346 Bergeron, Jr.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Raymond J. Bergeron, Jr. (Gainesville, Florida)
ABSTRACT Macular degeneration, closed head injury, stroke, irritable bowel disease, and reperfusion injury are all associated with biological injury due to reactive oxygen species, probably due to focal iron overload in many instances. The present invention provides methods and pharmaceutical compositions for treating these diseases and conditions using desferrithiocin analogs of Formula (I). In certain embodiments, the analogs include a poly ether moiety at the 4′-position of the phenyl ring of the compound.
FILED Friday, May 14, 2021
APPL NO 17/321210
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/426 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 277/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931352 Bushweller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia);  UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
ASSIGNEE(S) UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia);  UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) John H. Bushweller (Crozet, Virginia);  Anuradha Illendula (Crozet, Virginia);  Lucio Hernan Castilla (Boston, Massachusetts);  John Anto Pulikkan (Boston, Massachusetts)
ABSTRACT This invention relates to methods and compositions for treatment of inv (16) leukemia and particularly to treatment of acute myeloid leukemia. Disclosed is a method of treating inv (16) leukemia comprising the step of administering to a subject in in need thereof a therapeutically effective combination of a) a compound of the formula (1) (1) and b) a BRD4 inhibitor selected from the group consisting of JQ1, CeMMECZ, 1-BET 151 (or GSK1210151A), 1-BET 762 (or GSK525762), PFI-1, bromosporine, OTX-015 (or MK-8628), TEN-010, CPI-203, CPI-0610, RVX-208, BI2536, TG101348, LY294002, ABBV-075 (or mivebresib), FT-1101, ZEN003694, pharmaceutically acceptable salts and mixtures thereof. The therapeutically effective combination synergistically inhibits proliferation of inv (16) leukemia cells. This invention also relates to pharmaceutical compositions comprising a therapeutically effective combination of the compound of formula (1) and the BRD4 inhibitor and a pharmaceutically acceptable excipient.
FILED Friday, May 24, 2019
APPL NO 17/056459
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/444 (20130101) Original (OR) Class
A61K 31/551 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931356 Androphy et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) THE TRUSTEES OF INDIANA UNIVERSITY (Indianapolis, Indiana);  KOVINA THERAPEUTICS INC. (Indianapolis, Indiana)
ASSIGNEE(S) The Trustees of Indiana University (Indianapolis, Indiana);  Kovina Therapeutics, Inc. (Indianapolis, Indiana)
INVENTOR(S) Elliot J. Androphy (Indianapolis, Indiana);  Samy O. Meroueh (Carmel, Indiana);  Zhijian Lu (Indianapolis, Indiana)
ABSTRACT The invention provides compositions, compounds, formulations, and methods for treating HPV infections including pre-malignant infections and cancer. Compounds that covalently bind to the HPV E6 protein are disclosed.
FILED Wednesday, November 30, 2022
APPL NO 18/060391
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/51 (20130101)
A61K 31/496 (20130101) Original (OR) Class
A61K 31/517 (20130101)
A61K 31/519 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931364 Southerland et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
National Institute of Dental and Craniofacial Research (NIDCR)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Meharry Medical College (Nashville, Tennessee)
ASSIGNEE(S) Meharry Medical College (Nashville, Tennessee)
INVENTOR(S) Janet H. Southerland (Nashville, Tennessee);  Pandu R. Gangula (Nashville, Tennessee)
ABSTRACT Pharmaceutical compositions and methods of treatment or prevention of diseases and conditions associated with or characterized by at least one of xerostomia and periodontal disease by modulation of the nitric oxide synthase pathway are provided, as are animal models and drug screening methods. Such modulation may be achieved by the administration of tetrahydrobiopterin (BH4) or its prodrugs and/or salts. Treating and preventing xerostomia can have the downstream effect of also preventing periodontitis, dental caries, parotid gland enlargement, inflammation and fissuring of the lips (chelitis), inflammation or ulcers of the tongue and buccal mucosa, oral candidiasis, salivary gland infection (sialadenitis), halitosis, and cracking and fissuring of oral mucosa.
FILED Monday, September 19, 2022
APPL NO 17/948184
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/10 (20130101)
A61K 9/0056 (20130101)
A61K 9/0058 (20130101)
A61K 9/0063 (20130101)
A61K 31/519 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/02 (20180101)
A61P 5/48 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931366 Pak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Stephen Pak (St. Louis, Missouri);  David Perlmutter (St. Louis, Missouri);  Gary Silverman (St. Louis, Missouri)
ABSTRACT The present disclosure relates generally compositions and methods of using the same for the treatment of proteinopathies (e.g. Alpha-1-antitrypsin deficiency, Non-alcoholic fatty liver disease, Alzheimer's disease, Parkinson's disease, Amyotrophic Lateral Sclerosis, and Huntington's disease) with one or more proteotoxicity reducing agents.
FILED Friday, April 19, 2019
APPL NO 17/048957
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/135 (20130101)
A61K 31/138 (20130101)
A61K 31/155 (20130101)
A61K 31/444 (20130101)
A61K 31/505 (20130101)
A61K 31/4418 (20130101)
A61K 31/4453 (20130101)
A61K 31/5355 (20130101)
A61K 31/5415 (20130101) Original (OR) Class
A61K 31/7135 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 43/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931373 Dickey et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Veterans Health Administration (VHA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of South Florida (Tampa, Florida);  University of Kansas (Lawrence, Kansas)
ASSIGNEE(S) University of South Florida (Tampa, Florida);  University of Kansas (Lawrence, Kansas)
INVENTOR(S) Chad Dickey (Tampa, Florida);  Lindsey Shelton (Tampa, Florida);  Brian Blagg (Lawrence, Kansas);  John Koren (Tampa, Florida);  Laura Jenelle Blair (Tampa, Florida)
ABSTRACT Disclosed herein are compounds and methods for inhibiting Aha1 for the treatment of tauopathies and neurodegenerative diseases. The Aha1 inhibitor may reduce the interaction between Aha1 and Hsp90. The Aha1 inhibitor may reduce aggregation of tau protein. The Aha1 inhibitor may include a compound selected from KU-177, KU-174, and KU-308.
FILED Friday, April 15, 2022
APPL NO 17/722011
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/366 (20130101)
A61K 31/7048 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931380 Albelda et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Steven M. Albelda (Philadelphia, Pennsylvania);  Liang-Chuan Wang (Philadelphia, Pennsylvania);  Gary Koretzky (Thorton, Pennsylvania);  Matthew Riese (Mequon, Wisconsin)
ABSTRACT The present invention provides compositions and methods for inhibiting one or more diacylglycerol kinase (DGK) isoform in a cell in order to enhance the cytolytic activity of the cell. In one embodiment, the cells may be used in adoptive T cell transfer. For example, in some embodiments, the cell is modified to express a chimeric antigen receptor (CAR). Inhibition of DGK in T cells used in adoptive T cell transfer increases cytolytic activity of the T cells and thus may be used in the treatment of a variety of conditions, including cancer, infection, and immune disorders.
FILED Wednesday, April 14, 2021
APPL NO 17/230791
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class
A61K 38/00 (20130101)
A61K 38/45 (20130101)

Peptides
C07K 2/00 (20130101)
C07K 16/30 (20130101)
C07K 16/40 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0638 (20130101)
C12N 9/16 (20130101)
C12N 15/1137 (20130101)
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)
C12N 2310/14 (20130101)
C12N 2310/531 (20130101)
C12N 2310/531 (20130101)

Enzymes
C12Y 207/01107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931399 Stinchcomb et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) TAKEDA VACCINES, INC. (Cambridge, Massachusetts)
ASSIGNEE(S) Takeda Vaccines, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Dan T. Stinchcomb (Enumclaw, Washington);  Claire Kinney (Fort Collins, Colorado);  Richard M. Kinney (Fort Collins, Colorado);  Jill A. Livengood (Fort Collins, Colorado)
ABSTRACT Embodiments herein report compositions, uses and manufacturing of dengue virus constructs and live attenuated dengue viruses. Some embodiments concern a composition that includes, but is not limited to, a tetravalent dengue virus composition. In certain embodiments, compositions can include constructs of one or more serotypes of dengue virus, such as dengue-1 (DEN-1) virus, dengue-2 (DEN-2) virus, dengue-3 (DEN-3) or dengue-4 (DEN-4) virus constructs. In other embodiments, constructs disclosed herein can be combined in a composition to generate a vaccine against more one or more dengue virus constructs that may or may not be subsequently passaged in mammalian cells.
FILED Monday, December 12, 2022
APPL NO 18/064775
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 31/7048 (20130101)
A61K 38/162 (20130101) Original (OR) Class
A61K 39/12 (20130101)
A61K 2039/70 (20130101)
A61K 2039/5254 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 14/005 (20130101)
C07K 14/1825 (20130101)
C07K 19/00 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/09 (20130101)
C12N 15/8613 (20130101)
C12N 2770/24122 (20130101)
C12N 2770/24134 (20130101)
C12N 2770/24141 (20130101)
C12N 2770/24143 (20130101)
C12N 2770/24162 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931402 Kapiloff et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Anchored RSK3 Inhibitors, LLC (Los Altos, California)
ASSIGNEE(S) Anchored RSK3 Inhibitors, LLC (, None)
INVENTOR(S) Michael S. Kapiloff (Los Altos, California);  Jinliang Li (Palo Alto, California);  Michael Kritzer (Cambridge, Massachusetts)
ABSTRACT The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAPβ, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAPβ binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3.
FILED Friday, January 21, 2022
APPL NO 17/580692
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101)
A61K 31/713 (20130101)
A61K 31/7048 (20130101)
A61K 38/005 (20130101)
A61K 38/45 (20130101)
A61K 38/1709 (20130101) Original (OR) Class
A61K 48/00 (20130101)
A61K 48/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1137 (20130101)
C12N 2310/14 (20130101)
C12N 2750/14143 (20130101)

Enzymes
C12Y 207/11001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931403 Fan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) UNIVERSITY OF MISSISSIPPI MEDICAL CENTER (Jackson, Mississippi)
ASSIGNEE(S) UNIVERSITY OF MISSISSIPPI MEDICAL CENTER (Jackson, Mississippi)
INVENTOR(S) Lir-Wan Fan (Brandon, Mississippi);  Abhay Jyotindrabhai Bhatt (Ridgeland, Mississippi)
ABSTRACT A method for treating or reducing a likelihood of hypoxia-ischemia induced brain damage and neurobehavioral dysfunction in neonates utilizes a relative high dose of nasally administered insulin. In one aspect, the method includes intranasally administering, to a neonate in need thereof, an effective dose of insulin comprising between 350 U to 2000 U insulin.
FILED Wednesday, June 03, 2020
APPL NO 16/891789
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0043 (20130101)
A61K 38/28 (20130101) Original (OR) Class

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 31/00 (20130101)
A61M 2210/0618 (20130101)
A61M 2210/0693 (20130101)
A61M 2240/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931416 Blake et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Tim R. Blake (Palo Alto, California);  Paul Wender (Palo Alto, California);  Robert M. Waymouth (Palo Alto, California);  Ronald Levy (Palo Alto, California);  Ole Audun Werner Haabeth (Palo Alto, California);  Rebecca McClellan (Palo Alto, California);  Adrienne Sallets (Palo Alto, California)
ABSTRACT There are provided herein, inter alia, cationic amphipathic polymers, complexes, and compositions comprising same, and methods for their use including for the delivery of therapeutic, diagnostic and imaging agents, including nucleic acids, into a cell. The complexes, compositions and methods may facilitate delivery and targeted release of the therapeutic, diagnostic and imaging agents to particular cell types and tissues.
FILED Friday, January 31, 2020
APPL NO 17/427362
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/007 (20130101)
A61K 47/549 (20170801)
A61K 47/593 (20170801) Original (OR) Class
A61K 48/0041 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/08 (20130101)
C08G 63/64 (20130101)
C08G 63/685 (20130101)
C08G 73/028 (20130101)
C08G 73/0293 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931425 Bradbury et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Memorial Sloan Kettering Cancer Center (New York, New York);  Cornell University (Ithaca, New York)
ASSIGNEE(S) Memorial Sloan Kettering Cancer Center (New York, New York);  Cornell University (Ithaca, New York)
INVENTOR(S) Michelle S. Bradbury (New York, New York);  Ulrich Wiesner (Ithaca, New York);  Michael Overholtzer (Glen Ridge, New Jersey);  Howard Scher (Tenafly, New Jersey);  Kai Ma (Ithaca, New York)
ABSTRACT Described herein is a method of induced cell death via ferroptosis by nanoparticle ingestion. Moreover, the present disclosure describes the administration of high concentrations of ultrasmall nanoparticles at multiple times over the course of treatment in combination with a nutrient-depleted environment, thereby modulating cellular metabolic pathways to induce cell death by the mechanism ferroptosis. Ferroptosis involves iron, reactive oxygen species, and a synchronous mode of cell death execution.
FILED Thursday, December 30, 2021
APPL NO 17/566015
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/22 (20130101)
A61K 47/60 (20170801)
A61K 47/6923 (20170801)
A61K 47/6929 (20170801) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931480 Di Carlo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Dino Di Carlo (Los Angeles, California);  Westbrook Weaver (San Diego, California);  Tatiana Segura (Durham, North Carolina);  Philip Scumpia (Los Angeles, California);  Donald R. Griffin (Charlottesville, Virginia)
ABSTRACT A hydrogel material for modulating an immune response in a human subject or other mammal includes a collection of microgel particles having one or more network cross linker components, wherein the microgel particles, when exposed to an endogenous or exogenous annealing agent, links the microgel particles together in situ to form a covalently-stabilized scaffold of microgel particles having interstitial spaces formed between the microgel particles and wherein the collection of microgel particles further includes at least one of an antigen and an adjuvant.
FILED Tuesday, February 14, 2017
APPL NO 16/077985
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/1635 (20130101)
A61K 9/1641 (20130101)
A61K 9/1652 (20130101)
A61K 39/39 (20130101)
A61K 2039/60 (20130101)
A61K 2039/6093 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/52 (20130101) Original (OR) Class
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 2300/64 (20130101)
A61L 2300/426 (20130101)
A61L 2400/06 (20130101)

Derivatives of Natural Macromolecular Compounds
C08H 1/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931481 Di Carlo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Dino Di Carlo (Los Angeles, California);  Westbrook Weaver (San Diego, California);  Tatiana Segura (Durham, North Carolina);  Jaekyung Koh (Los Angeles, California);  Philip Scumpia (Los Angeles, California);  Donald R. Griffin (Charlottesville, Virginia)
ABSTRACT A hydrogel material for use in a human subject or other mammal includes a collection of microgel particles having one or more network cross linker components, wherein the microgel particles, when exposed to an endogenous or exogenous annealing agent, links the microgel particles together in situ to form a covalently-stabilized scaffold of microgel particles having pores formed between the microgel particles wherein the pores are substantially devoid of hydrogel.
FILED Saturday, July 30, 2022
APPL NO 17/877933
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/1635 (20130101)
A61K 9/1641 (20130101)
A61K 9/1652 (20130101)
A61K 39/39 (20130101)
A61K 2039/60 (20130101)
A61K 2039/6093 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/52 (20130101) Original (OR) Class
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 2300/64 (20130101)
A61L 2300/426 (20130101)
A61L 2400/06 (20130101)

Derivatives of Natural Macromolecular Compounds
C08H 1/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931482 Shukla et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) BROWN UNIVERSITY (Providence, Rhode Island);  Rhode Island Hospital (Providence, Rhode Island)
ASSIGNEE(S) BROWN UNIVERSITY (Providence, Rhode Island);  Rhode Island Hospital (Providence, Rhode Island)
INVENTOR(S) Anita Shukla (Providence, Rhode Island);  Beth Fuchs (Quincy, Massachusetts);  Hanyang Liu (E. Providence, Rhode Island);  Eleftherios Mylonakis (Providence, Rhode Island)
ABSTRACT The invention provides an auranofin-releasing antibacterial and antibiofilm polyurethane (PU) catheter coating. Auranofin is an antirheumatic drug with recently identified antimicrobial properties.
FILED Wednesday, March 18, 2020
APPL NO 16/823163
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 29/16 (20130101) Original (OR) Class
A61L 29/085 (20130101)
A61L 2300/102 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/14 (20130101)
C09D 175/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931739 Roussie et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) SiMPore Inc. (West Henrietta, New York);  University of Rochester (Rochester, New York)
ASSIGNEE(S) SiMPore Inc. (West Henrietta, New York);  University of Rochester (Rochester, New York)
INVENTOR(S) James A. Roussie (Rochester, New York);  James L. McGrath (Fairport, New York);  Richard E. Waugh (Pittsford, New York);  Kilean S. Lucas (Bozeman, Montana);  Joshua J. Miller (Rochester, New York)
ABSTRACT Provided are methods, devices, and kits for the isolation and detection of one or more analytes of interest from a biological sample using microslit filter membranes. In various examples, the methods use capture particles and binding agents for specific recognition of one or more analytes of interest.
FILED Thursday, August 16, 2018
APPL NO 16/639471
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502753 (20130101) Original (OR) Class
B01L 2300/0681 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/4077 (20130101)
G01N 33/537 (20130101)
G01N 2001/4088 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931893 Alambeigi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Laurel, Maryland)
INVENTOR(S) Farshid Alambeigi (Austin, Texas);  Reza Seifabadi (Baltimore, Maryland);  Mehran Armand (Maple Lawn, Maryland)
ABSTRACT A continuum device/manipulator includes a first flexible tube, a low melting point (LMP) alloy disposed within the first flexible tube, and a temperature adjustment element that applies heat or cooling to change a phase of the LMP alloy. Changing the phase of the LMP alloy controls a flexibility of the first flexible tube.
FILED Tuesday, May 12, 2020
APPL NO 16/872519
ART UNIT 3651 — Material and Article Handling
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/0051 (20130101)
A61B 1/0055 (20130101)
A61B 1/00078 (20130101)
A61B 1/128 (20130101)
A61B 2017/00411 (20130101)
A61B 2017/00955 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 25/005 (20130101)
A61M 25/0054 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/06 (20130101) Original (OR) Class
B25J 9/065 (20130101)
B25J 9/1095 (20130101)
B25J 15/00 (20130101)
B25J 15/12 (20130101)
B25J 18/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931969 Hudson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Andrew Hudson (Pittsburgh, Pennsylvania);  Thomas Hinton (Pittsburgh, Pennsylvania);  Adam Feinberg (Pittsburgh, Pennsylvania);  Andrew Lee (Pittsburgh, Pennsylvania)
ABSTRACT This document describes systems and method of embedded printing for additive manufacturing. A print material is printed into a support material. The print material and the support material each have a fluid phase and a solid phase. The print material transitions from the fluid phase to the solid phase based on a fluid-fluid interaction with the support material. One or more parameters of the support material can be adjusted to cause a diffusion rate of the print material into the support material during the fluid-fluid interaction to be less than a threshold value. Multiple print materials can be printed into the support material simultaneously.
FILED Friday, April 06, 2018
APPL NO 16/603173
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/20 (20130101)
A61L 27/24 (20130101)
A61L 27/52 (20130101)
A61L 27/56 (20130101)
A61L 27/222 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/40 (20170801) Original (OR) Class
B29C 64/106 (20170801)
B29C 64/165 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 30/00 (20141201)
B33Y 70/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932625 Gray et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Nathanael S. Gray (Stanford, California);  Tinghu Zhang (Brookline, Massachusetts);  Baishan Jiang (Brookline, Massachusetts);  Nicholas Paul Kwiatkowski (Brookline, Massachusetts)
ABSTRACT The present invention provides novel compounds of Formulae (I′) and (II), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating and/or preventing proliferative diseases (e.g., cancers (e.g., leukemia, acute lymphoblastic leukemia, lymphoma, Burkitt's lymphoma, melanoma, multiple myeloma, breast cancer, Ewing's sarcoma, osteosarcoma, brain cancer, ovarian cancer, neuroblastoma, lung cancer, colorectal cancer), benign neoplasms, diseases associated with angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of a kinase, such as a cyclin-dependent kinase (CDK) (e.g., CDK12), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject.
FILED Monday, March 07, 2022
APPL NO 17/688822
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 401/14 (20130101)
C07D 403/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932626 Pathak et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Southern Research Institute (Birmingham, Alabama);  Oregon Health and Science University (Portland, Oregon)
ASSIGNEE(S) Southern Research Institute (Birmingham, Alabama);  Oregon Health and Science University (Portland, Oregon)
INVENTOR(S) Ashish Kumar Pathak (Birmingham, Alabama);  Corinne E. Augelli-Szafran (Homewood, Alabama);  Atefeh Garzan (Hoover, Alabama);  Daniel Steblow (Banks, Oregon);  Nicole Haese (Beaverton, Oregon)
ABSTRACT The present disclosure is concerned with 2-pyrimidone compounds that are capable of inhibiting a viral infection and methods of treating alphavirus viral infections such as, for example, chikungunya, Eastern equine encephalitis (EEEV), Western equine encephalitis (WEEV), and Venezuelan equine encephalitis using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Tuesday, December 13, 2022
APPL NO 18/080692
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 213/69 (20130101)
C07D 213/70 (20130101)
C07D 213/74 (20130101)
C07D 403/04 (20130101) Original (OR) Class
C07D 491/052 (20130101)
C07D 498/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932628 Haskell-Luevano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota);  TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (Port St. Lucie, Florida)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Carrie Haskell-Luevano (Minneapolis, Minnesota);  Skye Ross Doering (Minneapolis, Minnesota);  Marcello A. Giulianotti (Port St. Lucie, Florida);  Clemencia Pinilla (Port St. Lucie, Florida);  Radleigh G. Santos (Port St. Lucie, Florida);  Richard A. Houghten (Port St. Lucie, Florida)
ABSTRACT The invention provides compounds having the general formula I:
and salts thereof, wherein the variables R1, R2, R3 and R4 have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.
FILED Monday, January 03, 2022
APPL NO 17/567201
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/485 (20130101)
A61K 9/2013 (20130101)
A61K 9/2027 (20130101)
A61K 9/2054 (20130101)
A61K 9/2059 (20130101)
A61K 9/4858 (20130101)
A61K 9/4866 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/04 (20180101)

Heterocyclic Compounds
C07D 403/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932650 Movassaghi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Tufts Medical Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Tufts Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Mohammad Movassaghi (Lincoln, Massachusetts);  Alyssa H. Antropow (Boston, Massachusetts);  Rachel J. Buchsbaum (Winchester, Massachusetts);  Kun Xu (Dorchester, Massachusetts)
ABSTRACT The present disclosure relates to derivatized agelastatin compounds and methods for the treatment, prevention, or delay of cancer, comprising administering a therapeutically effect amount of the derivatized agelastatin compounds, a pharmaceutically acceptable salt thereof, or a composition thereof to a subject in need thereof. Methods for making the derivatized agelastatin compounds are also provided.
FILED Friday, May 11, 2018
APPL NO 16/612468
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)

Heterocyclic Compounds
C07D 487/14 (20130101) Original (OR) Class
C07D 498/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932664 Slusher et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland);  INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR v.v.i. (Prague, Czech Republic)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSTY (Baltimore, Maryland);  INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY AS CR V.V.I. (Prague, Czech Republic)
INVENTOR(S) Barbara Slusher (Kingsville, Maryland);  Rana Rais (Kingsville, Maryland);  Marcela Krecmerova (Prague, Czech Republic);  Tomas Tichy (Prague, Czech Republic);  Pavel Majer (Sykesville, Maryland);  Andrej Jancarik (Koprivnice, Czech Republic)
ABSTRACT Methods and compounds are disclosed for treating a disease or condition by inhibiting PSMA (Prostate Specific Membrane Antigen) using prodrugs of 2-PMPA.
FILED Monday, May 09, 2022
APPL NO 17/739669
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/3808 (20130101)
C07F 9/4006 (20130101)
C07F 9/4075 (20130101)
C07F 9/4084 (20130101)
C07F 9/4087 (20130101)
C07F 9/4465 (20130101)
C07F 9/65586 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932668 Deverman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
NIH Office of the Director (NIHOD)
National Institute of Mental Health (NIMH)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Benjamin E. Deverman (Pasadena, California);  Paul H. Patterson (Altadena, California);  Viviana Gradinaru (La Cañada Flintridge, California)
ABSTRACT Provided herein are methods of selective screening. In addition, various targeting proteins and sequences, as well as methods of their use, are also provided.
FILED Friday, August 13, 2021
APPL NO 17/402317
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)
A61K 38/47 (20130101)
A61K 38/50 (20130101)
A61K 38/1709 (20130101)
A61K 38/2093 (20130101)
A61K 38/4813 (20130101)
A61K 39/3955 (20130101)
A61K 48/005 (20130101)
A61K 48/0058 (20130101)

Peptides
C07K 7/06 (20130101)
C07K 14/005 (20130101) Original (OR) Class
C07K 2319/33 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 15/1068 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14145 (20130101)
C12N 2810/6027 (20130101)

Enzymes
C12Y 304/14009 (20130101)
C12Y 305/01015 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932670 Harding et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) VaxNewMo LLC (St. Louis, Missouri)
ASSIGNEE(S) VaxNewMo LLC (St. Louis, Missouri)
INVENTOR(S) Christian Harding (St. Louis, Missouri);  Mario Feldman (St. Louis, Missouri)
ABSTRACT Provided herein are glycosylated ComP proteins, fragments and fusion proteins thereof, and methods of making, for example, for use in the production of conjugate vaccines. Also provided herein are conjugate vaccines against diseases including bacterial diseases.
FILED Friday, June 14, 2019
APPL NO 17/251994
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/05 (20130101)
A61K 39/092 (20130101)
A61K 39/0266 (20130101)
A61K 2039/575 (20130101)
A61K 2039/6037 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Peptides
C07K 14/195 (20130101) Original (OR) Class
C07K 2319/55 (20130101)
C07K 2319/91 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932691 Balakrishnan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Fred Hutchinson Cancer Center (Seattle, Washington)
ASSIGNEE(S) Fred Hutchinson Cancer Center (Seattle, Washington)
INVENTOR(S) Ashwini Balakrishnan (Seattle, Washington);  Benjamin G. Hoffstrom (Seattle, Washington);  Julie Randolph-Habecker (Yakima, Washington);  Stanley R. Riddell (Sammamish, Washington)
ABSTRACT The present disclosure relates to anti-ROR1 binding proteins, including those that bind to a ROR1 or portion thereof such as an intracellular C terminal portion of a ROR1 protein, and the use of such binding proteins in immunohistochemical and diagnostic methods. Related kits and methods of using the binding proteins are also provided, as are methods of treatment of subjects having diseases or conditions determined to be candidates for such treatments by the binding proteins or methods of this disclosure.
FILED Monday, January 25, 2021
APPL NO 17/157810
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 16/2803 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/33 (20130101)
C07K 2317/34 (20130101)
C07K 2317/92 (20130101)
C07K 2317/622 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57492 (20130101)
G01N 2333/70503 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932839 Kim et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia)
INVENTOR(S) YongTae Kim (Atlanta, Georgia);  Song lh Ahn (Atlanta, Georgia);  Taeyoung Kim (Atlanta, Georgia);  Jeongkee Yoon (Atlanta, Georgia)
ABSTRACT The present invention relates to a microfluidic device for simulating the structure and function of an in vivo tissue barrier. Specifically, the present invention relates to a microfluidic device that can be used as a model for new drug development and toxicity assessment and the like by simulating the structure and function of a two-dimensional-three-dimensional connective tissue barrier or a three-dimensional tissue barrier and thus replacing animal models, a method of culturing cells in the microfluidic device, and a method of simulating an organ or a body part using the microfluidic device.
FILED Monday, December 07, 2020
APPL NO 17/114282
ART UNIT 1799 — Organic Chemistry
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101) Original (OR) Class
C12M 23/42 (20130101)
C12M 25/02 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/502 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932848 Dekker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Job Dekker (Princeton, Massachusetts);  Josee Dostie (Montreal, Canada)
ABSTRACT The present invention relates to genomic analysis. In particular, the present invention provides methods and compositions for mapping genomic interactions.
FILED Thursday, August 18, 2022
APPL NO 17/890661
ART UNIT 1675 — Organic Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1072 (20130101) Original (OR) Class
C12N 15/1093 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932850 Siegfried et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Jill M. Siegfried (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Jill M. Siegfried, LLC (Pittsburgh, Pennsylvania)
INVENTOR(S) Jill M. Siegfried (Minneapolis, Minnesota);  Christian Nzinkeu Njatcha (Minneapolis, Minnesota);  Mariya Farooqui (Minneapolis, Minnesota)
ABSTRACT Described herein are compositions that inhibit/degrade STAT3, and methods of using such compositions for chemoprevention of non-small cell lung cancer (NSCLC).
FILED Thursday, March 28, 2019
APPL NO 17/042708
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/517 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/11 (20130101)
C12N 2310/13 (20130101)
C12N 2310/314 (20130101)
C12N 2310/315 (20130101)
C12N 2310/531 (20130101)
C12N 2310/532 (20130101)
C12N 2310/3183 (20130101)
C12N 2310/3231 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57484 (20130101)
G01N 2333/5412 (20130101)
G01N 2333/90245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932856 Mali et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Prashant Mali (La Jolla, California);  Dhruva Katrekar (La Jolla, California)
ABSTRACT Aspects of the disclosure relate to a gene therapy approach for diseases, disorders, or conditions caused by mutation in the stop codon utilizing modified tRNA. At least 10-15% of all genetic diseases, including muscular dystrophy (e.g. Duchene muscular dystrophy), some cancers, beta thalassemia, Hurler syndrome, and cystic fibrosis, fall into this category. Not to be bound by theory, it is believed that this approach is safer than CRISPR approaches due to minimal off-target effects and the lack of genome level changes.
FILED Friday, March 02, 2018
APPL NO 16/490494
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 21/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/78 (20130101)
C12N 15/113 (20130101)
C12N 15/115 (20130101) Original (OR) Class
C12N 15/1137 (20130101)
C12N 2310/20 (20170501)
C12N 2310/531 (20130101)
C12N 2320/34 (20130101)

Enzymes
C12Y 305/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932877 Wauthier et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Eliane Wauthier (Chapel Hill, North Carolina);  Tsunekazu Oikawa (Chapel Hill, North Carolina);  Timothy Anh-Hieu Dinh (Chapel Hill, North Carolina);  Praveen Sethupathy (Chapel Hill, North Carolina);  Lola M. Reid (Chapel Hill, North Carolina)
ABSTRACT The present disclosure provides a model of human fibrolamellar hepatocellular carcinoma (FL-HCC) cells maintained as a transplantable tumor line in a host and a method to establish a transplantable human FL-HCC tumor line. Methods of ex vivo cultures of the FL-HCC are provided. Methods of diagnosing and treating FL-HCC tumors are also provided.
FILED Monday, June 18, 2018
APPL NO 16/011534
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0271 (20130101)
A01K 2207/12 (20130101)
A01K 2227/105 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0693 (20130101) Original (OR) Class
C12N 2503/02 (20130101)
C12N 2513/00 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/158 (20130101)

Enzymes
C12Y 305/01098 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5067 (20130101)
G01N 33/57438 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932884 Liu et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David R. Liu (Cambridge, Massachusetts);  Kevin Tianmeng Zhao (Cambridge, Massachusetts);  Yongjoo Kim (Cambridge, Massachusetts)
ABSTRACT Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins comprise a Gam protein, a napDNAbp, and a cytidine deaminase. In some embodiments, the fusion proteins further comprise a UGI domain. In some embodiments, methods for targeted nucleic acid editing are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of a Gam protein, a cytidine deaminase and nucleic acid editing proteins or domains, are provided.
FILED Monday, March 21, 2022
APPL NO 17/700109
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 2319/09 (20130101)
C07K 2319/80 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/78 (20130101) Original (OR) Class
C12N 15/62 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932908 Delgado-Escueta et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  RIKEN (Saitama, Japan);  INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ (Delegacion Tlalpan, Mexico);  U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia);  Marco Tulio Medina-Hernandez (Los Angeles, California)
ASSIGNEE(S)
INVENTOR(S) Antonio V. Delgado-Escueta (Malibu, California);  Kazuhiro Yamakawa (Saitama, Japan);  Toshimitsu Suzuki (Saitama, Japan);  Marco Tulio Medina-Hernandez (Tegucigalpa, China PRC);  Maria Elisa Alonso Vilatela (Delegacion Coyoacan, Mexico)
ABSTRACT Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.
FILED Monday, February 08, 2021
APPL NO 17/248798
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/118 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/172 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933781 Schwartz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Aging (NIA)
APPLICANT(S) The Regents of the University of Colorado (Aurora, Colorado)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF COLORADO (Aurora, Colorado)
INVENTOR(S) David Schwartz (Denver, Colorado);  Ian Stancil (Denver, Colorado)
ABSTRACT A method of screening a test compound, e.g., a fibrosis or IPF inhibitor, for induction of an unjammed-to-jammed transition (UJT) in fibrotic primary human bronchial epithelial cells (HBECs) isolated from a subject with a fibrotic lung disease includes culturing the fibrotic primary HBECs at an air-liquid interface for a time sufficient to provide a differentiated pseudostratified epithelium contacting the cultured cells with the test compound; and monitoring the motility of the cultured cells to identify the cultured cells as moving or stationary; wherein stationary cultured cells indicate that the test compound induces the UJT. Also included are methods of identifying lung fibrosis biomarkers.
FILED Thursday, December 09, 2021
APPL NO 17/546554
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5029 (20130101) Original (OR) Class
G01N 33/5044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933791 Apte et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Rajendra S. Apte (St. Louis, Missouri);  Jun Yoshino (St. Louis, Missouri)
ABSTRACT Provided herein are methods for determining the severity of glaucoma using expression levels of GDF15. Determining the severity of glaucoma can aid in making treatment decisions.
FILED Wednesday, August 25, 2021
APPL NO 17/411863
ART UNIT 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/475 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/112 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6893 (20130101) Original (OR) Class
G01N 2333/52 (20130101)
G01N 2800/52 (20130101)
G01N 2800/168 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933973 Gopinath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Juliet Gopinath (Boulder, Colorado);  Mo Zohrabi (Boulder, Colorado);  Victor M. Bright (Boulder, Colorado);  Omkar Supekar (Boulder, Colorado);  Robert H. Cormack (Erie, Colorado);  Emily Gibson (Boulder, Colorado);  Connor McCullough (Denver, Colorado)
ABSTRACT The present disclosure relates generally to methods and systems useful in imaging applications, especially biological imaging applications, and applications in the metrology, atmospheric, scientific and medical fields. In one aspect, the disclosure provides a method of imaging an object, including illuminating the object with incident radiation through one or more adaptive optical elements; receiving transmitted radiation from the object at a photodetector to provide a base image; and performing the following steps one or more times: adjusting the one or more adaptive optical elements, the adjustment including modifying an optical transfer function of the one or more adaptive optical elements, and receiving transmitted radiation from the object at the photodetector to provide an adjusted image; wherein the adjustment and receiving steps are performed until the adjusted image has substantially reduced aberrations compared to the base image.
FILED Wednesday, October 03, 2018
APPL NO 16/753615
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/06 (20130101)
G02B 27/0068 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935082 Cranshaw et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Justin Cranshaw (Pittsburgh, Pennsylvania);  Raz Schwartz (New York, New York);  Jason I. Hong (Pittsburgh, Pennsylvania);  Norman Sadeh-Koniecpol (Pittsburgh, Pennsylvania)
ABSTRACT Computer-based systems and methods for discovering neighborhood clusters in a geographic region, where the clusters have a mix of venues and are determined based on venue check-in data. The mix of venues for the clusters may be based on the social similarity between pairs of venues; or emblematic of certain neighborhood typologies; or emblematic of temporal check-in pattern types; or combinations thereof. The neighborhood clusters that are so discovered through venue-check in data could be used for many commercial and civic purposes.
FILED Monday, January 10, 2022
APPL NO 17/572252
ART UNIT 3624 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 30/0205 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11936082 El Amili et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
Multidisciplinary University Research Initiative (MURI)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Library of Medicine (NLM)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Division of Electrical, Communications and Cyber Systems (ECCS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Abdelkrim El Amili (La Jolla, California);  Yeshaiahu Fainman (La Jolla, California);  Cheng-Yi Fang (La Jolla, California);  Hung-Hsi Lin (La Jolla, California)
ABSTRACT Microwave photonic devices use light to carry and process microwave signals over a photonic link. Light can be used as a stimulus to microwave devices that directly control microwave signals. Previous optically controlled devices suffer from large footprint, high optical power level required for switching, lack of scalability and complex integration requirements, restricting their implementation in practical microwave systems. Disclosed are monolithic optically reconfigurable integrated microwave switches (MORIMSs) built on a CMOS compatible silicon photonic chip. The disclosed scalable micrometer-scale switches provide higher switching efficiency and operate using optical power that is orders of magnitude lower than previous devices. The disclosed devices and techniques provide examples of silicon photonic platforms integrating microwave circuitry.
FILED Friday, August 28, 2020
APPL NO 17/006761
ART UNIT 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/011 (20130101)
G02F 1/21 (20130101)
G02F 1/212 (20210101)
G02F 1/0338 (20130101)
G02F 2201/16 (20130101)
G02F 2203/055 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 1/15 (20130101) Original (OR) Class
H01P 3/00 (20130101)
H01P 3/003 (20130101)
H01P 3/16 (20130101)
H01P 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US RE49873 John et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) BUCK INSTITUTE FOR RESEARCH ON AGING (Novato, California)
ASSIGNEE(S) BUCK INSTITUTE FOR RESEARCH ON AGING (Novato, California)
INVENTOR(S) Varghese John (San Francisco, California);  Dale E. Bredesen (Los Angeles, California)
ABSTRACT In certain embodiments APP-specific BACE inhibitors (ASBIs) are provided as well as uses thereof. In certain embodiments methods of preventing or delaying the onset of a pre-Alzheimer's condition and/or cognitive dysfunction, and/or ameliorating one or more symptoms of a pre-Alzheimer's condition and/or cognitive dysfunction, or preventing or delaying the progression of a pre-Alzheimer's condition or cognitive dysfunction to Alzheimer's disease are provided where the method involves administering to a subject in need thereof an APP specific BACE inhibitor (ASBI) in an amount sufficient to prevent or delay the onset of a pre-Alzheimer's cognitive dysfunction, and/or to ameliorate one or more symptoms of a pre-Alzheimer's cognitive dysfunction, and/or to prevent or delay the progression of a pre-Alzheimer's cognitive dysfunction to Alzheimer's disease. In certain embodiments the ASBI is a flavonoid (e.g. galangin) or flavonoid prodrug (e.g., galangin prodrug).
FILED Thursday, July 22, 2021
APPL NO 17/382969
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/352 (20130101)
A61K 31/366 (20130101)
A61K 31/7048 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 311/24 (20130101)
C07D 311/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11931045 Burkart et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Joseph Thomas Burkart (Bloomfield, Indiana);  Danielle E. Cafasso (Southern Pines, North Carolina);  Robert Henry Hayford (Colorado Springs, Colorado);  Huckelberry Finne (Norfolk, Virginia);  Jose Ramirez Vargas (Clovis, New Mexico);  Michael P Abbott (Chesapeake, Virginia)
ABSTRACT A junctional tourniquet apparatus and related methods of use. An exemplary tourniquet has an inverted cone shape, wherein a narrower end has a mushroom shaped base that is pressed against a compression target and a broader end has a plurality of pass-through slots for straps. Another exemplary tourniquet has a broad plate component and a handle component. The handle component has a mushroom shaped base on a first end and a handle on a second end. The handle component passes through the center of the plate component with threads that allow the handle component to compress a target by twisting the handle.
FILED Friday, January 07, 2022
APPL NO 17/570680
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/1325 (20130101) Original (OR) Class
A61B 17/1327 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931046 Burkart et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Joseph Thomas Burkart (Bloomfield, Indiana);  Danielle E. Cafasso (Southern Pines, North Carolina);  Robert Henry Hayford (Colorado Springs, Colorado);  Huckelberry A. Finne (Norfolk, Virginia);  Jose Ramirez Vargas (Clovis, New Mexico);  Michael P. Abbott (Chesapeake, Virginia)
ABSTRACT A junctional tourniquet apparatus and related methods of use. An exemplary tourniquet has an inverted cone shape, wherein a narrower end has a mushroom shaped base that is pressed against a compression target and a broader end has a plurality of pass-through slots for straps. Another exemplary tourniquet has a broad plate component and a handle component. The handle component has a mushroom shaped base on a first end and a handle on a second end. The handle component passes through the center of the plate component with threads that allow the handle component to compress a target by twisting the handle.
FILED Friday, January 13, 2023
APPL NO 18/097011
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/1325 (20130101) Original (OR) Class
A61B 17/1327 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931166 Argenta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S) Applied Research Associates, Inc. (Albuquerque, New Mexico)
ASSIGNEE(S) Applied Research Associates, Inc. (Albuquerque, New Mexico)
INVENTOR(S) Christopher Argenta (Albuquerque, New Mexico);  Aaron Williams (Albuquerque, New Mexico);  Greg Foderaro (Albuquerque, New Mexico);  Thomas Paniagua (Albuquerque, New Mexico)
ABSTRACT A system and method of generating an enhanced Lund and Browder chart and total body surface area burn score is described herein. In some embodiments, a plurality of images is obtained from of a patient using a camera system. The images may be taken by aligning the patient's body with pose templates presented on a display of the camera system. The non-skin portions of the images may be removed, and skin analysis performed on the skin portion to determine burn location, coverage, and depth. Further, landmarks may be detected in the images to morph and align the images with the pose templates to obtain standard poses. The plurality of images may be combined and presented in two-dimensional and three-dimensional models with labels and the total surface area burn score.
FILED Tuesday, July 07, 2020
APPL NO 16/922598
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0013 (20130101)
A61B 5/0075 (20130101)
A61B 5/0077 (20130101)
A61B 5/445 (20130101) Original (OR) Class
A61B 5/743 (20130101)
A61B 5/744 (20130101)
A61B 5/6898 (20130101)
A61B 5/7264 (20130101)
A61B 5/7282 (20130101)
A61B 2576/02 (20130101)

Image Data Processing or Generation, in General
G06T 7/0014 (20130101)
G06T 11/206 (20130101)
G06T 19/20 (20130101)
G06T 2219/2016 (20130101)

Image or Video Recognition or Understanding
G06V 10/42 (20220101)
G06V 10/44 (20220101)
G06V 10/143 (20220101)
G06V 20/20 (20220101)
G06V 2201/03 (20220101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931271 Bokser et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) Liberating Technologies, Inc. (Holliston, Massachusetts)
ASSIGNEE(S) Liberating Technologies, Inc. (Holliston, Massachusetts)
INVENTOR(S) Benjamin Bokser (Flushing, New York);  Kevin Keough (Sharon, Massachusetts);  Aaron Taszreak (China, Michigan);  Todd Farrell (Waltham, Massachusetts);  Jennifer Johansson (Wayland, Massachusetts);  Sangwoo Park (Moriches, New York);  Kevin Lawrence (Milford, Massachusetts)
ABSTRACT A prosthetic foot includes a foot portion and a switching adapter. The switching adapter includes a first member coupled to the foot portion, a second member, a third member interposed between the first member and the second member, and a locking mechanism. The third member has a first side wall and a second side wall larger in length than the first side wall. The third member is configured to rotate relative to the first member and the second member towards a first position, thereby placing the prosthetic device in a walking mode. The third member is further configured to rotate relative to the first member and the second member towards a second position, thereby placing the prosthetic device in a running mode. The locking mechanism is configured to rotate with the third member in response to rotation of the third member.
FILED Tuesday, February 01, 2022
APPL NO 17/590280
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/6607 (20130101) Original (OR) Class
A61F 2002/5018 (20130101)
A61F 2002/5069 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931406 Baumhof et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) CureVac SE (Tübingen, Germany);  Sanofi Pasteur (Lyons, France)
ASSIGNEE(S) CureVac SE (Tübingen, Germany);  Sanofi Pasteur (Lyons, France)
INVENTOR(S) Patrick Baumhof (Tübingen, Germany);  Wolfgang Grosse (Tübingen, Germany);  Edith Jasny (Tübingen, Germany);  Thomas Kramps (Tübingen, Germany);  Daniel Voss (Tübingen, Germany);  Julia Dannenmaier (Tübingen, Germany);  Valérie Lecouturier (Chazay d'Azergues, France);  Yves Girerd-Chambaz (Messimy, France)
ABSTRACT The present invention is directed to an artificial nucleic acid and to a polypeptide suitable for use in the treatment or prophylaxis of an infection with a flavivirus, in particular an infection with yellow fever virus or with dengue virus, or of a disorder related to such an infection. The present invention is also directed to a composition, preferably an immunogenic composition, comprising the artificial nucleic acid or the inventive polypeptide. In particular, the present invention concerns an immunogenic composition against a flavivirus, such as yellow fever virus or dengue virus. Further, the invention concerns a kit, particularly a kit of parts, comprising the artificial nucleic acid, polypeptide or (immunogenic) composition. The invention is further directed to a method of treating or preventing a disorder or a disease, first and second medical uses of the artificial nucleic acid, polypeptide, composition, in particular the first and second medical uses of the immunogenic composition according to the invention.
FILED Wednesday, December 12, 2018
APPL NO 16/772131
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/53 (20130101)
A61K 2039/575 (20130101)
A61K 2039/6031 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2770/24134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931482 Shukla et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) BROWN UNIVERSITY (Providence, Rhode Island);  Rhode Island Hospital (Providence, Rhode Island)
ASSIGNEE(S) BROWN UNIVERSITY (Providence, Rhode Island);  Rhode Island Hospital (Providence, Rhode Island)
INVENTOR(S) Anita Shukla (Providence, Rhode Island);  Beth Fuchs (Quincy, Massachusetts);  Hanyang Liu (E. Providence, Rhode Island);  Eleftherios Mylonakis (Providence, Rhode Island)
ABSTRACT The invention provides an auranofin-releasing antibacterial and antibiofilm polyurethane (PU) catheter coating. Auranofin is an antirheumatic drug with recently identified antimicrobial properties.
FILED Wednesday, March 18, 2020
APPL NO 16/823163
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 29/16 (20130101) Original (OR) Class
A61L 29/085 (20130101)
A61L 2300/102 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/14 (20130101)
C09D 175/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931820 Lee et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S) MERCURY MISSION SYSTEMS, LLC (Andover, Massachusetts)
ASSIGNEE(S) MERCURY MISSION SYSTEMS, LLC (Andover, Massachusetts)
INVENTOR(S) Kang Lee (Torrance, California);  Matthew Neil (Torrance, California);  Wayne Chan (Torrance, California);  Anthony Lai (Torrance, California);  Andrew Kostrzewski (Torrance, California)
ABSTRACT Systems and techniques are directed to a Swappable Retractable Tool Tip (SRTT), which is designed as a next generation of friction stir welding tools and retractable tool tips. The disclosed SRTT may be “swappable,” having different types of retractable tool tips that can be assembled and employed as a part of the SRTT. A SRTT system can include at least: a blank tool holder, a piston, and a retractable tool tip. In operation, the blank tool holder allows air to flow to cause movement of the piston and the retractable tool tip. For example, compressed air can push up on the piston and the retractable tool tip, retracting it into a “home” position inside of the blank tool holder. Also, the SRTT can include springs that push down on the piston and the retractable tool tip, extending the tip into an “extended” position outside of the blank tool holder.
FILED Thursday, December 17, 2020
APPL NO 17/125692
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 20/123 (20130101)
B23K 20/1255 (20130101) Original (OR) Class

Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/4145 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931881 O'Brien
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) US Govt as Reprsented by the Secy of the Air Force (Wright Patterson, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Courtney O'Brien (San Antonio, Texas)
ABSTRACT A tool box with vertically stacked monolithic trays. Each tray has pockets specifically shaped to receive complementary tools. The trays have upstanding cantilevered posts, which can space apart the superjacent tray. Alternatively, the posts can be received in complementary sockets of superjacent trays to prevent undue lateral movement while in the tool box. The post and socket geometry can be constructed to index the order in which trays are stacked and index how individual trays are oriented for optimal and sequenced access to the tools.
FILED Thursday, September 30, 2021
APPL NO 17/449467
ART UNIT 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Workshop Equipment, e.g for Marking-out Work; Storage Means for Workshops
B25H 3/06 (20130101)
B25H 3/026 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932365 Ripplinger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S) BATTLE SIGHT TECHNOLOGIES, LLC (Dayton, Ohio)
ASSIGNEE(S) Battle Sight Technologies, LLC (Dayton, Ohio)
INVENTOR(S) Nicholas R. Ripplinger (Dayton, Ohio);  David Charles Di Staulo (Dayton, Ohio);  Sunny L. Kapka (Dayton, Ohio);  Grant David Santo (Dayton, Ohio);  Jay Phillip-Donald Vallie (Dayton, Ohio);  Christopher J. Vogt (Dayton, Ohio);  Colton A. Whitman (Dayton, Ohio)
ABSTRACT An apparatus that facilitates search and rescue, for example, in open water. The apparatus comprises a substrate with a particular geometry and a perimeter. The apparatus further comprises a cover positioned atop the substrate with the cover also having a particular geometry and perimeter, which correspond to the geometry and perimeter of the substrate. An air-tight seal seals the substrate perimeter to the cover perimeter and creates a sealed internal region. A liquid-releasable vessel holding an illuminable dye located in the sealed internal region, along with an activator that is also located in the sealed internal region. When the liquid-releasable vessel releases the illuminable dye, the illuminable dye reacts with the activator, thereby resulting in illumination of the illuminable dye. The liquid-releasable vessel comprises an opening with a release mechanism (e.g., clamp, etc.).
FILED Wednesday, January 13, 2021
APPL NO 17/147527
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 2201/04 (20130101)
B63B 2201/22 (20130101)

Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects
B63C 9/00 (20130101) Original (OR) Class

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/07 (20130101)

Signalling or Calling Systems; Order Telegraphs; Alarm Systems
G08B 5/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932381 Dunn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
ASSIGNEE(S) LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
INVENTOR(S) Eric Dunn (Trumbull, Connecticut);  Keith M. Schenone (Fairfield, Connecticut);  Sven R. Lofstrom (Irving, Texas)
ABSTRACT According to an aspect, a method of assembling a mandrel includes assembling a plurality of members via interlocking features arranged at opposing edges of each member of the plurality of members to form a compartment, the assembled members having a collective outer surface that conforms to an inner surface of the spar. A support member is inserted into the compartment formed radially inward from the assembled members, the support member making contact with a portion of each member of the plurality of members.
FILED Monday, April 17, 2023
APPL NO 18/135253
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 33/485 (20130101)
B29C 53/824 (20130101)

Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 99/0028 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 80/00 (20141201)

Aeroplanes; Helicopters
B64C 27/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932389 Neely et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Jared Neely (Troy, Ohio);  James Joo (Centerville, Ohio)
ABSTRACT The present disclosure defines a morphing airfoil having a dynamic flexible skin system that is capable of carrying high level aerodynamic (or fluid) pressure loads over a structural surface. The structural surface can morph and deflect in response to control inputs to change a lift force without separate movable control surfaces. The anisotropic skin is attached to underlying structure that is both actively controlled and passively supported. A control system causes the underlying support structure to move to a desired location which in turn causes the skin to bend and/or flex without exceeding a stress threshold and thus vary the lift profile along a span of the airfoil.
FILED Tuesday, December 22, 2020
APPL NO 17/130448
ART UNIT 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Motor Vehicles; Trailers
B62D 37/02 (20130101)

Aeroplanes; Helicopters
B64C 3/26 (20130101)
B64C 3/48 (20130101) Original (OR) Class
B64C 3/182 (20130101)
B64C 13/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932625 Gray et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Nathanael S. Gray (Stanford, California);  Tinghu Zhang (Brookline, Massachusetts);  Baishan Jiang (Brookline, Massachusetts);  Nicholas Paul Kwiatkowski (Brookline, Massachusetts)
ABSTRACT The present invention provides novel compounds of Formulae (I′) and (II), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive compounds or compositions for treating and/or preventing proliferative diseases (e.g., cancers (e.g., leukemia, acute lymphoblastic leukemia, lymphoma, Burkitt's lymphoma, melanoma, multiple myeloma, breast cancer, Ewing's sarcoma, osteosarcoma, brain cancer, ovarian cancer, neuroblastoma, lung cancer, colorectal cancer), benign neoplasms, diseases associated with angiogenesis, inflammatory diseases, autoinflammatory diseases, and autoimmune diseases) in a subject. Treatment of a subject with a proliferative disease using a compound or composition of the invention may inhibit the aberrant activity of a kinase, such as a cyclin-dependent kinase (CDK) (e.g., CDK12), and therefore, induce cellular apoptosis and/or inhibit transcription in the subject.
FILED Monday, March 07, 2022
APPL NO 17/688822
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 401/14 (20130101)
C07D 403/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932650 Movassaghi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Tufts Medical Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Tufts Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Mohammad Movassaghi (Lincoln, Massachusetts);  Alyssa H. Antropow (Boston, Massachusetts);  Rachel J. Buchsbaum (Winchester, Massachusetts);  Kun Xu (Dorchester, Massachusetts)
ABSTRACT The present disclosure relates to derivatized agelastatin compounds and methods for the treatment, prevention, or delay of cancer, comprising administering a therapeutically effect amount of the derivatized agelastatin compounds, a pharmaceutically acceptable salt thereof, or a composition thereof to a subject in need thereof. Methods for making the derivatized agelastatin compounds are also provided.
FILED Friday, May 11, 2018
APPL NO 16/612468
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)

Heterocyclic Compounds
C07D 487/14 (20130101) Original (OR) Class
C07D 498/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932724 Harvey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Benjamin G. Harvey (Ridgecrest, California);  Kyle E. Rosenkoetter (Ridgecrest, California)
ABSTRACT A novel family of cycloalkanes compounds having one or more allylidene functionalities which can be used to create cross-linked thermosets and thermoplastics having thermal stability. An example heptacyclo [6.6.0.02,6.03,13.04,11.05,9.010,14] tetradecane (HCTD) complex with terminal allylidene groups at the 7- and 12-positions (HCTD-7,12-diallylidene) was generated from norbornadiene via an efficient six-step synthesis. Thermal polymerization at temperatures ranging from 160 to 240° C. yielded a robust cross-linked material with thermal stability up to 485° C. in air, a glass transition temperature of 377° C., and a char yield (600° C.) of 56% in air. Applications include heat resistant composites utilized in the aerospace, electronic, automotive and textile industries.
FILED Thursday, April 01, 2021
APPL NO 17/220282
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 1/20 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 36/02 (20130101)
C08F 2500/07 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 61/02 (20130101) Original (OR) Class
C08G 2261/13 (20130101)
C08G 2261/76 (20130101)
C08G 2261/592 (20130101)
C08G 2261/3325 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932739 Gunckel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Ryan Gunckel (Tempe, Arizona);  Lenore Dai (Phoenix, Arizona);  Aditi Chattopadhyay (Chandler, Arizona);  Bonsung Koo (Tempe, Arizona)
ABSTRACT Composite material can include a matrix material, a fiber dispersed in the matrix material, and an ultraviolet (UV)-light sensitive mechanophore grafted to a surface of the fiber. A method for making a fiber-reinforced polymer composite can include contacting a fiber in a first solution, rinsing and then drying intermediate fiber, contacting dried fiber in a third solution, rinsing, and then drying the rinsed fiber thereby generating functionalized fiber that is sensitive to ultraviolet light. The functionalized fiber can be combined with a polymer matrix material, cured, and irradiated, thereby generating a fiber-reinforced polymer composite.
FILED Tuesday, November 16, 2021
APPL NO 17/527905
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/28 (20130101)
C08J 5/08 (20130101) Original (OR) Class
C08J 5/042 (20130101)
C08J 2363/00 (20130101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/429 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932875 Livingston et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S) The Aerospace Corporation (El Segundo, California)
ASSIGNEE(S) THE AEROSPACE CORPORATION (El Segundo, California)
INVENTOR(S) Frank Edward Livingston (Redondo Beach, California);  Timothy Ganey (Tampa, Florida)
ABSTRACT A method of stimulating and controlling stem cell activity and differentiation on a modified material substrate and a device including the modified material substrate are provided. The method includes providing a material substrate configured for medical use. The material substrate includes at least one surface or interior area available for modification, and the at least one surface or interior area is treated with a plurality of pulsed light beams to obtain a modified material substrate with at least one modified surface or interior area. The at least one modified surface or interior area has a biomimetic architecture with surface and bulk (interior) features, properties, and textures configured to accelerate and control stem cell differentiation when the modified material substrate is contacted with stem cells.
FILED Thursday, May 07, 2020
APPL NO 16/869208
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/0622 (20151001)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0662 (20130101) Original (OR) Class
C12N 2529/10 (20130101)
C12N 2533/90 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932884 Liu et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David R. Liu (Cambridge, Massachusetts);  Kevin Tianmeng Zhao (Cambridge, Massachusetts);  Yongjoo Kim (Cambridge, Massachusetts)
ABSTRACT Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins comprise a Gam protein, a napDNAbp, and a cytidine deaminase. In some embodiments, the fusion proteins further comprise a UGI domain. In some embodiments, methods for targeted nucleic acid editing are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of a Gam protein, a cytidine deaminase and nucleic acid editing proteins or domains, are provided.
FILED Monday, March 21, 2022
APPL NO 17/700109
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 2319/09 (20130101)
C07K 2319/80 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 9/78 (20130101) Original (OR) Class
C12N 15/62 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933221 Anderson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Raytheon Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RTX Corporation (Farmington, Connecticut)
INVENTOR(S) Corey D. Anderson (East Hartford, Connecticut);  Edward Boucher (Watertown, Connecticut);  Rebecca R. Dunnigan (Sturbridge, Massachusetts);  Nicholas Broulidakis (Vernon, Connecticut);  Matthew Murakami (West Hartford, Connecticut);  Daniel R. Brandt (Easthampton, Connecticut);  Konrad Kuc (West Hartford, Connecticut);  Victoria M. Imlach (Marlborough, Connecticut);  Sushruth G. Kamath (Manchester, Connecticut);  Manuel A. Casares Rivas (East Hartford, Connecticut);  Eric G. Leamon (Manchester, Connecticut);  Adam Castles (Norwood, Massachusetts);  Edmond Cheung (East Hartford, Connecticut);  Kyra A. Thole-Wilson (West Hartford, Connecticut);  Javier Nebero Johnson (East Hartford, Connecticut)
ABSTRACT A gas turbine engine including a core having a compressor section fluidly connected to a combustor via a primary flowpath and a turbine section connected to the combustor via the core flow path. An assembly is disposed within the gas turbine engine and includes a first part connected to a second part via a radial stack joint. The first part includes a radially inward facing surface contacting a corresponding radially outward facing surface of the second part. A fastener protrudes through the first part and the second part and is configured to maintain the relative positions of the first part and the second part. A channel is disposed on at least one of the radially inward facing surfaces and is positioned between the fastener and a circumferential edge of the first part. The channel is connected to at least one cooling air source.
FILED Monday, October 17, 2022
APPL NO 17/967315
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/18 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2230/60 (20130101)
F05D 2260/232 (20130101)

Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers
F23R 3/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933524 Pei et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Qibing Pei (Calabasas, California);  Yuan Meng (Los Angeles, California)
ABSTRACT A device comprising one or more heat transfer laminates each including an electrode, a first dielectric layer on a first side of the electrode, and a second dielectric layer on a second side of the electrode; a plurality of flexible electrocaloric elements, each of the flexible electrocaloric elements including an electrocaloric material layer, a flexible electrode layer on the electrocaloric layer, one or more fixed portions each attached to one of heat transfer laminates, and a movable portion that is movable with respect to the one of the heat transfer laminates.
FILED Friday, September 10, 2021
APPL NO 17/472182
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 21/00 (20130101) Original (OR) Class
F25B 2321/001 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 15/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933568 Hammel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Rand W. Hammel (Springville, Indiana);  Alex J. Toon (Odon, Indiana);  Donald Richardville (Montgomery, Indiana)
ABSTRACT Provided is an interchangeable modular chamber system for a firearm. The system includes a firearm receiver, a barrel comprising lands and grooves, a chamber insert sleeve comprising lands and grooves, an index pin, a locking collar, and a recoil lug. The barrel is threaded into the receiver with the chamber insert sleeve positioned within the barrel. The chamber insert sleeve is indexed to align the lands and grooves of the chamber insert sleeve with those of the barrel. The locking collar and recoil lug are threaded onto the external threads of the barrel and are adjustable to optimize the headspace for different cartridges of the same caliber and to allow for the sacrificial replacement of the throat area of a barrel.
FILED Wednesday, April 06, 2022
APPL NO 17/714219
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 21/10 (20130101)
F41A 21/12 (20130101)
F41A 21/18 (20130101)
F41A 21/482 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933587 Beblo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Richard Beblo (Oakwood, Ohio);  Tizoc Cruz-Gonzalez (Dayton, Ohio);  Mackenzie Tidball (Beavercreek, Ohio);  Gregory Reich (Bellbrook, Ohio);  Benjamin Dickinson (Destin, Florida)
ABSTRACT The present disclosure is directed to a missile having a main body and an articulating nosecone connected to the main body. An actuation system is operable for moving the nosecone relative to the main body via one or more electric motors and associated components. A central aperture is formed through electric motors and the associated components between the main body and the nosecone. One or more cables for transmitting electrical power, sensor data, control signals and the like extend through the central aperture between the main body and the nosecone to provide means for controlling the actuation system.
FILED Thursday, November 03, 2022
APPL NO 17/979835
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 10/62 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933596 Bales et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) John Bales (Beavercreek, Ohio);  Alexander Orsi (Dayton, Ohio);  James Okeefe (Kettering, Ohio);  Kyle Schory (Dayton, Ohio);  Stuart Baker (Dayton, Ohio)
ABSTRACT A device and method for remote-controlled explosive ordnance disposal using an explosive ordnance disposal device that includes a carriage adjustably attached to a device frame having a rotatable bar. The rotatable bar including at least a laser face, an x-ray face, and a disarm device face; the rotatable bar rotated by a servo motor, the servomotor being remotely operable. The laser face having a laser capable of a laser beam visible to a remote viewing device. The remote viewing device co-mounted to the laser face and remotely viewable. The x-ray face having an x-ray device attached to it. The disarm device face having a bomb disarming device attached; wherein the carriage and the rotatable bar may be remotely adjusted such that upon remote rotation the laser, x-ray and bomb disarming device share an aligned orientation and placement for operation.
FILED Wednesday, September 29, 2021
APPL NO 17/488467
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Blasting
F42D 5/04 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933694 Smith et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) United States Government as Represented by the Secretary of the Air Force (Wright Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Paul Smith (Beavercreek, Ohio);  Tina Reynolds (Fairborn, Ohio)
ABSTRACT An instrumented wind tunnel. The wind tunnel receives a test subject which can be a model of an object to be tested with dynamic airflow. The test subject is fitted with at least one sensor to deliver data to a chassis, which in turn uses a network having at least 10 Gb/s capability to deliver the data to a RAM cache. The RAM cache can push the data to multiple viewers for real time monitoring of wind tunnel tests. The operator can then make live adjustments of the test conditions.
FILED Wednesday, August 18, 2021
APPL NO 17/445352
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 9/04 (20130101) Original (OR) Class

Electric Digital Data Processing
G06F 13/4027 (20130101)
G06F 16/252 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933749 Motes, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Materials and Manufacturing Directorate (MMD)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Texas Research International, Inc. (Austin, Texas)
ASSIGNEE(S) Texas Research International, Inc (Austin, Texas)
INVENTOR(S) Doyle T. Motes, III (Austin, Texas);  Marcus Keiser (Cedar Park, Texas);  Richard Piner (Austin, Texas)
ABSTRACT Non-destructive sensing methods and devices for inspection and measuring in manufacturing applications for removal of contaminants from composite surfaces coupled with sensing and activation of the composite surfaces.
FILED Friday, September 10, 2021
APPL NO 17/472533
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/225 (20130101)
G01N 23/2202 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933781 Schwartz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute on Aging (NIA)
APPLICANT(S) The Regents of the University of Colorado (Aurora, Colorado)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF COLORADO (Aurora, Colorado)
INVENTOR(S) David Schwartz (Denver, Colorado);  Ian Stancil (Denver, Colorado)
ABSTRACT A method of screening a test compound, e.g., a fibrosis or IPF inhibitor, for induction of an unjammed-to-jammed transition (UJT) in fibrotic primary human bronchial epithelial cells (HBECs) isolated from a subject with a fibrotic lung disease includes culturing the fibrotic primary HBECs at an air-liquid interface for a time sufficient to provide a differentiated pseudostratified epithelium contacting the cultured cells with the test compound; and monitoring the motility of the cultured cells to identify the cultured cells as moving or stationary; wherein stationary cultured cells indicate that the test compound induces the UJT. Also included are methods of identifying lung fibrosis biomarkers.
FILED Thursday, December 09, 2021
APPL NO 17/546554
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5029 (20130101) Original (OR) Class
G01N 33/5044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933973 Gopinath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Juliet Gopinath (Boulder, Colorado);  Mo Zohrabi (Boulder, Colorado);  Victor M. Bright (Boulder, Colorado);  Omkar Supekar (Boulder, Colorado);  Robert H. Cormack (Erie, Colorado);  Emily Gibson (Boulder, Colorado);  Connor McCullough (Denver, Colorado)
ABSTRACT The present disclosure relates generally to methods and systems useful in imaging applications, especially biological imaging applications, and applications in the metrology, atmospheric, scientific and medical fields. In one aspect, the disclosure provides a method of imaging an object, including illuminating the object with incident radiation through one or more adaptive optical elements; receiving transmitted radiation from the object at a photodetector to provide a base image; and performing the following steps one or more times: adjusting the one or more adaptive optical elements, the adjustment including modifying an optical transfer function of the one or more adaptive optical elements, and receiving transmitted radiation from the object at the photodetector to provide an adjusted image; wherein the adjustment and receiving steps are performed until the adjusted image has substantially reduced aberrations compared to the base image.
FILED Wednesday, October 03, 2018
APPL NO 16/753615
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/06 (20130101)
G02B 27/0068 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11934458 Ji et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The George Washington University (Washington, District of Columbia)
ASSIGNEE(S) The George Washington University (Washington, District of Columbia)
INVENTOR(S) Yuede Ji (Washington, District of Columbia);  Hao Howie Huang (McLean, Virginia)
ABSTRACT A binary code similarity detection system that compares a target binary code to a source code by comparing the target binary code to a comparing binary generated by compiling the source code. Rather than using a comparing binary generated using a random or fixed compiling configuration, the system identifies the compiling configuration of the target binary code and compares the target binary code to a comparing binary generated using the same compiling configuration as the target binary code. The compiling configuration of the target binary code may be identified by a neural network (e.g., a graph attention network trained on attributed function call graphs of binary codes with known compiling configurations). The target binary code and the comparing binary may be compared using a graph neural network (e.g., a graph triplet loss network) that compares attributed control flow graphs of the of the target binary code and the comparing binary.
FILED Friday, May 21, 2021
APPL NO 17/327351
ART UNIT 2192 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 8/41 (20130101)
G06F 8/751 (20130101)
G06F 16/9024 (20190101) Original (OR) Class
G06F 21/563 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/084 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11934479 Kachman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Tal Kachman (Haifa, Iceland);  Mark S. Squillante (Greenwich, Connecticut);  Lior Horesh (North Salem, New York);  Kenneth Lee Clarkson (Madison, New York);  John A. Gunnels (Somers, New York);  Ismail Yunus Akhalwaya (Emmarentia, Saudi Arabia);  Jayram Thathachar (Morgan Hill, California)
ABSTRACT A method for performing sparse quantum Fourier transform computation includes defining a set of quantum circuits, each quantum circuit comprising a Hadamard gate and a single frequency rotation operator, said set of quantum circuits being equivalent to a quantum Fourier transform circuit. The method includes constructing a subset of said quantum circuits in a quantum processor, said quantum processor having a quantum representation of a classical distribution loaded into a quantum state of said quantum processor. The method includes executing said subset of said quantum circuits on said quantum state, and performing a measurement in a frequency basis to obtain a frequency distribution corresponding to said quantum state.
FILED Wednesday, October 07, 2020
APPL NO 17/065277
ART UNIT 2182 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 17/141 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11934922 Awasthy et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Parul Awasthy (Ossining, New York);  Bishwaranjan Bhattacharjee (Yorktown Heights, New York);  John Ronald Kender (Leonia, New York);  Radu Florian (Danbury, Connecticut);  Hui Wan (White Plains, New York)
ABSTRACT A computer system, product, and method are provided. The computer system includes an artificial intelligence (AI) platform operatively coupled to a processor. The AI platform includes tools in the form of a machine learning model (MLM) manager, a metric manager, and a training manager. The MLM manager accesses a plurality of pre-trained source MLMs, and inputs a plurality of data objects of a test dataset into each of the source MLMs. The test dataset includes the plurality of data objects associated with respective labels. For each source MLM, associated labels are generated from the inputted data objects and a similarity metric is calculated. The MLM manager selects a base MLM to be used for transfer learning from the plurality of source MLMs based upon the calculated similarity metric. The training manager trains the selected base MLM with a target dataset for the target domain.
FILED Friday, October 09, 2020
APPL NO 17/066685
ART UNIT 3682 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Electric Digital Data Processing
G06F 16/285 (20190101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11934968 Stillerman
FUNDED BY
Department of Defense (DOD)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) Architecture Technology Corporation (Minneapolis, Minnesota)
ASSIGNEE(S) ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota)
INVENTOR(S) Matthew A. Stillerman (Ithaca, New York)
ABSTRACT A method and system for determining predictably feasible model designs. The method includes defining a plurality of model designs, wherein the plurality of model designs include a plurality of infeasible model designs, wherein one or more of the infeasible model designs are infeasible due to limits in technology; storing information representing a plurality of technological trends; and classifying one or more of the infeasible model designs as predictably feasible model designs, wherein the predictable feasible model designs are those infeasible model designs expected to become feasible model designs if one or more of the plurality of technological trends continues as anticipated.
FILED Tuesday, January 16, 2018
APPL NO 15/872645
ART UNIT 2126 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 5/041 (20130101) Original (OR) Class
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935600 Brewer
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Micron Technology, Inc. (Boise, Idaho)
ASSIGNEE(S) Micron Technology, Inc. (Boise, Idaho)
INVENTOR(S) Tony Brewer (Plano, Texas)
ABSTRACT Devices and techniques for programmable atomic operator resource locking are described herein. A request for a programmable atomic operator (PAO) can be received at a memory controller that includes a programmable atomic unit (PAU). Here, the request includes an identifier for the PAO and a memory address. The memory addressed is processed to identify a lock value. A verification can be performed to determine that the lock value indicates that there is no lock corresponding to the memory address. Then, the lock value is set to indicate that there is now a lock corresponding to the memory address and the PAO is invoked based on the identifier for the PAO. In response to completion of the PAO, the lock value is set to indicate that there is no longer a lock corresponding to the memory address.
FILED Monday, March 06, 2023
APPL NO 18/117900
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/526 (20130101)
G06F 12/0815 (20130101)
G06F 12/0862 (20130101)
G06F 12/0875 (20130101)
G06F 13/1605 (20130101)
G06F 13/1668 (20130101)
G06F 2212/1024 (20130101)

Static Stores
G11C 16/08 (20130101)
G11C 16/26 (20130101)
G11C 16/102 (20130101) Original (OR) Class
G11C 16/3459 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935667 Houten et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Spark Thermionics, Inc. (Emeryville, California)
ASSIGNEE(S) Spark Thermionics, Inc. (Berkeley, California)
INVENTOR(S) Kyana Van Houten (Berkeley, California);  Lucas Heinrich Hess (Berkeley, California);  Jared William Schwede (Berkeley, California);  Felix Schmitt (Berkeley, California)
ABSTRACT A thermionic energy conversion system, preferably including one or more electron collectors, interfacial layers, encapsulation, and/or electron emitters. A method for manufacturing the thermionic energy conversion system. A method of operation for a thermionic energy conversion system, preferably including receiving power, emitting electrons, and receiving the emitted electrons, and optionally including convectively transferring heat.
FILED Monday, December 20, 2021
APPL NO 17/555907
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Obtaining Energy From Radioactive Sources; Applications of Radiation From Radioactive Sources, Not Otherwise Provided For; Utilising Cosmic Radiation
G21H 1/106 (20130101) Original (OR) Class

Electric Discharge Tubes or Discharge Lamps
H01J 45/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935938 Shen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Pin-Chun Shen (Changhua, Taiwan);  Jing Kong (Winchester, Massachusetts)
ABSTRACT Devices, such as transistors, that use bismuth to create ohmic contacts are provided, as are methods of manufacturing the same. The transistors, such as field-effect transistors, can include one or more two-dimensional materials, and electrical contact areas can be created on the two-dimensional material(s) using bismuth. The bismuth can help to provide energy-barrier free, ohmic contacts, and the resulting devices can have performance levels that rival or exceed state-of-the-art devices that utilize three-dimensional materials, like silicon. The two-dimensional materials can include transition metal dichalcogenides, such as molybdenum disulfide.
FILED Thursday, May 13, 2021
APPL NO 17/320183
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/45 (20130101)
H01L 29/4983 (20130101) Original (OR) Class
H01L 29/66628 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11936082 El Amili et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
Multidisciplinary University Research Initiative (MURI)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Library of Medicine (NLM)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Division of Electrical, Communications and Cyber Systems (ECCS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Abdelkrim El Amili (La Jolla, California);  Yeshaiahu Fainman (La Jolla, California);  Cheng-Yi Fang (La Jolla, California);  Hung-Hsi Lin (La Jolla, California)
ABSTRACT Microwave photonic devices use light to carry and process microwave signals over a photonic link. Light can be used as a stimulus to microwave devices that directly control microwave signals. Previous optically controlled devices suffer from large footprint, high optical power level required for switching, lack of scalability and complex integration requirements, restricting their implementation in practical microwave systems. Disclosed are monolithic optically reconfigurable integrated microwave switches (MORIMSs) built on a CMOS compatible silicon photonic chip. The disclosed scalable micrometer-scale switches provide higher switching efficiency and operate using optical power that is orders of magnitude lower than previous devices. The disclosed devices and techniques provide examples of silicon photonic platforms integrating microwave circuitry.
FILED Friday, August 28, 2020
APPL NO 17/006761
ART UNIT 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/011 (20130101)
G02F 1/21 (20130101)
G02F 1/212 (20210101)
G02F 1/0338 (20130101)
G02F 2201/16 (20130101)
G02F 2203/055 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 1/15 (20130101) Original (OR) Class
H01P 3/00 (20130101)
H01P 3/003 (20130101)
H01P 3/16 (20130101)
H01P 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11936421 Corzine et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Regents of the University of California (Oakland, California);  The Government of the United States of America, as Represented by the Secretary of the Navy (Monterey, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERISTY OF CALIFORNIA (Oakland, California);  THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia)
INVENTOR(S) Keith Corzine (Santa Cruz, California);  Todd Weatherford (Santa Cruz, California);  Matthew Porter (Santa Cruz, California)
ABSTRACT An optically-monitored and/or optically-controlled electronic device is described. The device includes at least one of a semiconductor transistor or a semiconductor diode. An optical detector is configured to detect light emitted by the at least one of the semiconductor transistor or the semiconductor diode during operation. A signal processor is configured to communicate with the optical detector to receive information regarding the light detected. The signal processor is further configured to provide information concerning at least one of an electrical current flowing in, a temperature of, or a condition of the at least one of the semiconductor transistor or the semiconductor diode during operation.
FILED Thursday, February 23, 2023
APPL NO 18/113500
ART UNIT 2634 — Digital Communications
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/28 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/12007 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 33/32 (20130101)

Transmission
H04B 10/071 (20130101) Original (OR) Class
H04B 10/801 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11936782 Cambou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona)
INVENTOR(S) Bertrand F. Cambou (Flagstaff, Arizona);  Ines Montano (Flagstaff, Arizona);  Ryan Behunin (Flagstaff, Arizona);  Vince Rodriguez (Flagstaff, Arizona)
ABSTRACT The performance of quantum key distribution by systems and methods that use wavelength division multiplexing and encode information using both wavelength and polarization of photons of two or more wavelengths. Multi-wavelength polarization state encoding schemes allow ternary-coded digits, quaternary-coded digits and higher-radix digits to be represented by single photons. Information expressed in a first radix can be encoded in a higher radix and combined with a string of key values to produce a datastream having all allowed digit values of that radix in a manner that allows eavesdropping to be detected without requiring the sender and receiver to exchange additional information after transmission of the information.
FILED Wednesday, February 01, 2023
APPL NO 18/104705
ART UNIT 2432 — Cryptography and Security
CURRENT CPC
Transmission
H04B 10/70 (20130101)
H04B 10/07957 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0858 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11937361 McDonald et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Research Laboratory (NRL)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Michael McDonald (Springfield, Virginia);  Marcel Georgin (Washington, District of Columbia)
ABSTRACT A cathode emitter assembly includes a cathode tube having a gas feed portion and a plasma outflow portion; an outer annular cathode insert in the plasma outflow portion of the cathode tube; an inner cathode insert in the plasma outflow section of the cathode tube; and an annular plasma emission portion defined between an inner surface of the outer annular cathode insert and an outer surface of the inner cathode insert.
FILED Wednesday, February 09, 2022
APPL NO 17/668344
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/405 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/481 (20210501) Original (OR) Class
H05H 1/3442 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11937363 Kobernik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Energy (DOE)
APPLICANT(S) SHINE Technologies, LLC (Janesville, Wisconsin)
ASSIGNEE(S) SHINE Technologies, LLC (Janesville, Wisconsin)
INVENTOR(S) Arne Kobernik (Monona, Wisconsin);  Carl Sherven (Monona, Wisconsin);  Casey Lamers (Monona, Wisconsin);  Chris Seyfert (Monona, Wisconsin);  Evan Sengbusch (Monona, Wisconsin);  Gabriel Becerra (Monona, Wisconsin);  Jin Lee (Monona, Wisconsin);  Logan Campbell (Monona, Wisconsin);  Mark Thomas (Monona, Wisconsin);  Michael Taylor (Monona, Wisconsin);  Preston Barrows (Monona, Wisconsin);  Ross Radel (Monona, Wisconsin);  Tye Gribb (Monona, Wisconsin)
ABSTRACT Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes.
FILED Monday, January 09, 2023
APPL NO 18/094726
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 37/08 (20130101)
H01J 37/32082 (20130101)
H01J 41/04 (20130101)
H01J 41/14 (20130101)

Spark Gaps; Overvoltage Arresters Using Spark Gaps; Sparking Plugs; Corona Devices; Generating Ions to be Introduced into Non-enclosed Gases
H01T 23/00 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 31/26 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/46 (20130101)
H05H 1/54 (20130101)
H05H 1/4622 (20210501)
H05H 3/06 (20130101)
H05H 5/04 (20130101)
H05H 6/00 (20130101)
H05H 7/22 (20130101) Original (OR) Class
H05H 9/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11937519 Bromberg et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) TECO Westinghouse Motor Company (Round Rock, Texas)
ASSIGNEE(S) TECO-WESTINGHOUSE MOTOR COMPANY (Round Rock, Texas)
INVENTOR(S) Leslie Bromberg (Sharon, Massachusetts);  Dean Sarandria (Jonestown, Texas);  Edward Kuan-Chen Chen (Austin, Texas);  Gabriel Rupertus (Austin, Texas)
ABSTRACT Permanent magnets using high temperature superconductor tapes are disclosed. For example, a magnet may include a superconductor tape having two ends, a slit in the superconductor tape between the two ends that forms two legs, a separation between the legs that forms a loop, and a trapped magnetic field in the superconductor tape.
FILED Friday, March 15, 2013
APPL NO 13/815975
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Electric solid-state devices not otherwise provided for
H10N 60/83 (20230201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11931138 Tathireddy et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Applied Biosensors, LLC (Salt Lake City, Utah)
ASSIGNEE(S) Applied Biosensors, LLC (Salt Lake City, Utah)
INVENTOR(S) Prashant Tathireddy (Salt Lake City, Utah);  Rohit Sharma (Salt Lake City, Utah);  Seung Hei Cho (Salt Lake City, Utah);  Nicholas Frazier (Salt Lake City, Utah);  Yoonsung Goo (Salt Lake City, Utah)
ABSTRACT A hydrogel sensor device can include a crosslinked hydrogel body which changes in volume in response to an environmental stimulus, a support post positioned to mechanically support the crosslinked hydrogel body during the change in volume, and a sensor positioned to detect the change in volume in the crosslinked hydrogel body.
FILED Friday, December 14, 2018
APPL NO 16/221003
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/06 (20130101) Original (OR) Class
A61B 2562/04 (20130101)
A61B 2562/16 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/24 (20130101)
C08J 3/075 (20130101)

Compositions of Macromolecular Compounds
C08L 33/04 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/72 (20130101)
G01N 33/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931163 Perelman
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts)
INVENTOR(S) Lev T. Perelman (Brookline, Massachusetts)
ABSTRACT Described herein are embodiments of an approach to diagnosing pancreatic cystic lesions using light scattering spectroscopy. In some embodiments, the approach includes an apparatus including a spatial gating probe to isolate light reflected by the epithelial tissue of the internal cyst surface using spatial gating. In some further embodiments, the apparatus includes a scanning fiber probe that is capable of rotational and linear motion in order to scan the entire internal surface of the cyst. Use of such an approach may be advantageous to improve the accuracy of diagnosing pancreatic cystic lesions as cancerous, precancerous, or benign.
FILED Friday, February 23, 2018
APPL NO 16/487768
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0075 (20130101)
A61B 5/0084 (20130101)
A61B 5/425 (20130101) Original (OR) Class
A61B 8/0841 (20130101)
A61B 10/0045 (20130101)
A61B 2010/0061 (20130101)
A61B 2562/0242 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931416 Blake et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Tim R. Blake (Palo Alto, California);  Paul Wender (Palo Alto, California);  Robert M. Waymouth (Palo Alto, California);  Ronald Levy (Palo Alto, California);  Ole Audun Werner Haabeth (Palo Alto, California);  Rebecca McClellan (Palo Alto, California);  Adrienne Sallets (Palo Alto, California)
ABSTRACT There are provided herein, inter alia, cationic amphipathic polymers, complexes, and compositions comprising same, and methods for their use including for the delivery of therapeutic, diagnostic and imaging agents, including nucleic acids, into a cell. The complexes, compositions and methods may facilitate delivery and targeted release of the therapeutic, diagnostic and imaging agents to particular cell types and tissues.
FILED Friday, January 31, 2020
APPL NO 17/427362
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/007 (20130101)
A61K 47/549 (20170801)
A61K 47/593 (20170801) Original (OR) Class
A61K 48/0041 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/08 (20130101)
C08G 63/64 (20130101)
C08G 63/685 (20130101)
C08G 73/028 (20130101)
C08G 73/0293 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931478 Becker et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Matthew Becker (Chapel Hill, North Carolina);  Yanyi Xu (Cuyahoga Falls, Ohio)
ASSIGNEE(S) The University of Akron (Akron, Ohio)
INVENTOR(S) Matthew Becker (Chapel Hill, North Carolina);  Yanyi Xu (Cuyahoga Falls, Ohio)
ABSTRACT In various aspects, the present invention is directed to novel bioactive peptide loaded poly(propylene fumarate) (PPF) tissue scaffolds and related methods for their making and use. In various embodiments, these bioactive peptide loaded poly(propylene fumarate) tissue scaffolds are formed by forming a PPF structure or matrix using photochemical 3-D printing techniques and then loading that printed PPF structure or matrix with a bioactive peptides or other bioactive compounds that have, or have been functionalized to have, a thiol functional group at or near its terminus. The thiol groups on the bioactive peptides or other compound will react with exposed alkene functional groups on the PPF polymer matrix via a thiol-ene “click” reaction, thereby binding these bioactive peptides or other compounds to the tissue scaffolds. The bioactive peptide loaded PPF tissue scaffolds of the present invention are particularly useful in repairing bone defects.
FILED Thursday, May 03, 2018
APPL NO 16/609772
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101) Original (OR) Class
A61L 27/44 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 27/58 (20130101)
A61L 27/3808 (20130101)
A61L 27/3821 (20130101)
A61L 27/3834 (20130101)
A61L 2300/25 (20130101)
A61L 2300/252 (20130101)
A61L 2300/404 (20130101)
A61L 2300/412 (20130101)
A61L 2300/414 (20130101)
A61L 2430/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931907 Rus et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Daniela Rus (Weston, Massachusetts);  Jeffrey Lipton (Medford, Massachusetts);  Aidan Fay (La Jolla, California);  Changhyun Choi (Minneapolis, Minnesota)
ABSTRACT In some aspects, a system comprises a computer hardware processor and a non-transitory computer-readable storage medium storing processor-executable instructions for receiving, from one or more sensors, sensor data relating to a robot; generating, using a statistical model, based on the sensor data, first control information for the robot to accomplish a task; transmitting, to the robot, the first control information for execution of the task; and receiving, from the robot, a result of execution of the task.
FILED Friday, February 25, 2022
APPL NO 17/680748
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/163 (20130101)
B25J 9/1689 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932084 Palmisano
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Faiveley Transport NSF (Neuville-en-Ferrain, France)
ASSIGNEE(S) FAIVELEY TRANSPORTATION NSF (Neuville-en-Ferrain, France)
INVENTOR(S) Domenico Palmisano (Marcq en Baroeul, France)
ABSTRACT A method for determining a level of refrigerant charge in a cooling circuit of an air-conditioning system and a module for leak detection are provided. The method includes determining a total quantity of refrigerant contained in the cooling circuit of the air-conditioning system solely based on data internal to the air-conditioning system.
FILED Friday, December 27, 2019
APPL NO 17/419615
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles
B60H 1/3222 (20130101)
B60H 1/3225 (20130101) Original (OR) Class
B60H 1/3227 (20130101)
B60H 2001/3238 (20130101)
B60H 2001/3248 (20130101)
B60H 2001/3255 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932557 Shi et al.
FUNDED BY
National Science Foundation (NSF)
Department of Agriculture (USDA)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
INVENTOR(S) Jian Shi (Lexington, Kentucky);  Wenqi Li (Lexington, Kentucky);  Jameson Hunter (Lexington, Kentucky);  Yuxuan Zhang (Lexington, Kentucky);  Qing Shao (Lexington, Kentucky)
ABSTRACT Methods for detecting and extracting plastic contaminants within a water sample, which involve introducing the water sample to a hydrophobic deep eutectic solvent, are provided.
FILED Tuesday, June 29, 2021
APPL NO 17/362515
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 11/0492 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/26 (20130101) Original (OR) Class
C02F 2101/34 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/94 (20130101)
G01N 33/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932734 Qi et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Hang Qi (Atlanta, Georgia);  Kai Yu (Atlanta, Georgia);  Qian Shi (Atlanta, Georgia);  Xiao Kuang (Atlanta, Georgia)
ABSTRACT Various methods of reshaping and recycling thermoset polymers and composites containing thermoset polymers are provided. The methods involve the bond exchange reaction of exchangeable covalent bonds in the polymer matrix with a suitable small molecule solvent in the presence of a catalyst. In some aspects, the methods are applied to a carbon fiber reinforced polymer or a thermoset polymer where the thermoset polymer matrix includes a plurality of ester bonds. Using a small molecule alcohol, the methods provide for recycling one or both of the carbon fiber and the polymer, for welding two surfaces, or for repairing a damaged surface in the materials.
FILED Friday, August 12, 2022
APPL NO 17/819335
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 4/16 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/195 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/04 (20130101)
C08J 5/24 (20130101)
C08J 5/121 (20130101)
C08J 11/24 (20130101) Original (OR) Class
C08J 2363/00 (20130101)
C08J 2367/06 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/103 (20130101)
C08K 7/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932752 Hersam et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Mark C. Hersam (Wilmette, Illinois);  Ana Carolina Mazarin de Moraes (Chicago, Illinois)
ABSTRACT A composite film usable as a separator of an electrochemical device includes hBN nanosheets and at least one polymer. The hBN nanosheets are uniformly dispersed within a matrix of said least one polymer to achieve a highly porous microstructure. Said at least one polymer comprises one or more electrically insulating and electrochemically inert polymers.
FILED Friday, July 24, 2020
APPL NO 17/626602
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/04 (20130101)
C08K 3/38 (20130101)
C08K 9/02 (20130101) Original (OR) Class
C08K 2003/385 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932789 Dobereiner et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) Temple University- of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) Graham Dobereiner (Philadelphia, Pennsylvania);  William Sabbers (Philadelphia, Pennsylvania);  Weerasiri Arachchige Kushan Chandana Weerasiri (Philadelphia, Pennsylvania)
ABSTRACT Provided herein are luminescent compounds, compositions including the same, and use and synthesis thereof.
FILED Wednesday, November 11, 2020
APPL NO 17/095520
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/027 (20130101)
C07F 9/6506 (20130101)
C07F 9/65515 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101) Original (OR) Class
C09K 2211/188 (20130101)

Organic electric solid-state devices
H10K 50/11 (20230201)
H10K 85/371 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932923 Luo et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Alan Luo (Columbus, Ohio);  Emre Cinkilic (Columbus, Ohio);  Michael Moodispaw (Columbus, Ohio)
ABSTRACT Disclosed are aluminum alloys with high iron content and methods of making and using.
FILED Wednesday, September 29, 2021
APPL NO 17/489038
ART UNIT 1738 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Alloys
C22C 1/026 (20130101)
C22C 21/02 (20130101) Original (OR) Class

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932960 Tao et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Meng Tao (Fountain Hills, Arizona);  Laidong Wang (Cupertino, California)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Meng Tao (Fountain Hills, Arizona);  Laidong Wang (Cupertino, California)
ABSTRACT Methods for light-induced electroplating of aluminum are disclosed herein. Exemplary methods may comprise preparing an ionic liquid comprising aluminum chloride (AlCl3) and an organic halide, placing the silicon substrate into the ionic liquid, illuminating the silicon substrate, the illumination passing through the ionic liquid, and depositing aluminum onto the silicon substrate via a light-induced electroplating process, wherein the light-induced electroplating process utilizes an applied current that does not exceed a photo-generated current generated by the illumination.
FILED Thursday, April 21, 2022
APPL NO 17/725855
ART UNIT 1759 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/54 (20130101)
C25D 3/665 (20130101) Original (OR) Class
C25D 5/10 (20130101)
C25D 5/011 (20200801)
C25D 5/50 (20130101)
C25D 7/12 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/028 (20130101)
H01L 31/068 (20130101)
H01L 31/0682 (20130101)
H01L 31/1804 (20130101)
H01L 31/022425 (20130101)
H01L 31/022458 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932966 Li et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Wenzhi Li (Palmetto Bay, Florida);  Yuba Poudel (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Wenzhi Li (Palmetto Bay, Florida);  Yuba Poudel (Miami, Florida)
ABSTRACT Filled carbon nanotubes (CNTs) and methods of synthesizing the same are provided. An in situ chemical vapor deposition technique can be used to synthesize CNTs filled with metal sulfide nanowires. The CNTs can be completely and continuously filled with the metal sulfide fillers up to several micrometers in length. The filled CNTs can be easily collected from the substrates used for synthesis using a simple ultrasonication method.
FILED Friday, January 06, 2023
APPL NO 18/151309
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 32/162 (20170801)
C01B 32/178 (20170801)
C01B 2202/06 (20130101)
C01B 2202/10 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2002/82 (20130101)
C01P 2002/84 (20130101)
C01P 2004/03 (20130101)
C01P 2004/04 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/26 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 25/186 (20130101)
C30B 29/46 (20130101)
C30B 29/66 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933681 Li et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
ASSIGNEE(S) CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania)
INVENTOR(S) Lu Li (Pittsburgh, Pennsylvania);  H. Benjamin Brown (Pittsburgh, Pennsylvania);  Michael Schwerin (Pittsburgh, Pennsylvania);  Howie Choset (Pittsburgh, Pennsylvania)
ABSTRACT A force sensor comprising a force sensitive resistor having a common electrode and an electrode array separated by a force sensitive resistor material. The sensor includes a preload structure, where the preload structure imparts a force on the force sensitive resistor material. The sensor may also include a signal conditioning board to read a signal from the electrode array and convert it to a digital output.
FILED Monday, September 23, 2019
APPL NO 17/277382
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/22 (20130101) Original (OR) Class
G01L 5/1627 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933778 Wanunu et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) Northeastern University (Boston, Massachusetts);  University of York (York, United Kingdom)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts);  University of York (York, United Kingdom)
INVENTOR(S) Meni Wanunu (Needham, Massachusetts);  Alfred Antson (York, United Kingdom);  Sandra Greive (York, United Kingdom);  Benjamin Cressiot (Montlignon, France)
ABSTRACT Hybrid nanopores, comprising a protein pore supported within a solid-state membrane, which combine the robust nature of solid-state membranes with the easily tunable and precise engineering of protein nanopores. In an embodiment, a lipid-free hybrid nanopore comprises a water soluble and stable, modified portal protein of the Thermus thermophilus bacteriophage G20c, electrokinetically inserted into a larger nanopore in a solid-state membrane. The hybrid pore is stable and easy to fabricate, and exhibits low peripheral leakage, allowing sensing and discrimination among different types of biomolecules.
FILED Wednesday, June 29, 2022
APPL NO 17/809705
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 1/002 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 15/00 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2795/00022 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/48721 (20130101) Original (OR) Class

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 930/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933864 Javor et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) Trustees of Boston University (Boston, Massachusetts)
ASSIGNEE(S) Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) Joshua Javor (Cambridge, Massachusetts);  David Bishop (Brookline, Massachusetts);  David Campbell (Brookline, Massachusetts);  Matthias Imboden (St. Blaise, Switzerland)
ABSTRACT A system and method of effectively measuring a change in a gradient of a magnetic field. The systems include a first magnet and a second magnet mechanically coupled together and aligned along a polarization axis. The first magnet and the second magnet are positioned such that a pair of like magnetic poles of the first magnet and the second magnet face in opposite directions. Further, the first magnet and the second magnet are configured to move along the polarization axis in response to a magnetic field. A sensing system is configured to measure a change in a gradient of the magnetic field based on the movement of the first magnet and second magnet along the polarization axis in response to the magnetic field.
FILED Thursday, May 18, 2023
APPL NO 18/199185
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/022 (20130101) Original (OR) Class
G01R 33/038 (20130101)
G01R 33/0052 (20130101)
G01R 33/0385 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933939 Yi et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Ya Sha Yi (Troy, Michigan);  Mao Ye (Dearborn, Michigan)
ABSTRACT A metalens configured to shape the focus light into a flexibly designed pattern. The present teachings demonstrate the engineering of metalens with artificial focus pattern by creating line and ring-shaped focus as ‘drawing tools’. These metalens are fabricated through a single layer of silicon-based material through CMOS compatible nano fabrication process. The mechanism to generate artificial focus pattern can be applied to a plethora of future on-chip optical devices with applications ranging from beam engineering to next generation nano lithography.
FILED Thursday, June 24, 2021
APPL NO 17/357076
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101) Original (OR) Class
G02B 27/42 (20130101)
G02B 2207/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933973 Gopinath et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado (Denver, Colorado)
INVENTOR(S) Juliet Gopinath (Boulder, Colorado);  Mo Zohrabi (Boulder, Colorado);  Victor M. Bright (Boulder, Colorado);  Omkar Supekar (Boulder, Colorado);  Robert H. Cormack (Erie, Colorado);  Emily Gibson (Boulder, Colorado);  Connor McCullough (Denver, Colorado)
ABSTRACT The present disclosure relates generally to methods and systems useful in imaging applications, especially biological imaging applications, and applications in the metrology, atmospheric, scientific and medical fields. In one aspect, the disclosure provides a method of imaging an object, including illuminating the object with incident radiation through one or more adaptive optical elements; receiving transmitted radiation from the object at a photodetector to provide a base image; and performing the following steps one or more times: adjusting the one or more adaptive optical elements, the adjustment including modifying an optical transfer function of the one or more adaptive optical elements, and receiving transmitted radiation from the object at the photodetector to provide an adjusted image; wherein the adjustment and receiving steps are performed until the adjusted image has substantially reduced aberrations compared to the base image.
FILED Wednesday, October 03, 2018
APPL NO 16/753615
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 21/06 (20130101)
G02B 27/0068 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11934458 Ji et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Division of Computer and Network Systems (CNS)
APPLICANT(S) The George Washington University (Washington, District of Columbia)
ASSIGNEE(S) The George Washington University (Washington, District of Columbia)
INVENTOR(S) Yuede Ji (Washington, District of Columbia);  Hao Howie Huang (McLean, Virginia)
ABSTRACT A binary code similarity detection system that compares a target binary code to a source code by comparing the target binary code to a comparing binary generated by compiling the source code. Rather than using a comparing binary generated using a random or fixed compiling configuration, the system identifies the compiling configuration of the target binary code and compares the target binary code to a comparing binary generated using the same compiling configuration as the target binary code. The compiling configuration of the target binary code may be identified by a neural network (e.g., a graph attention network trained on attributed function call graphs of binary codes with known compiling configurations). The target binary code and the comparing binary may be compared using a graph neural network (e.g., a graph triplet loss network) that compares attributed control flow graphs of the of the target binary code and the comparing binary.
FILED Friday, May 21, 2021
APPL NO 17/327351
ART UNIT 2192 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 8/41 (20130101)
G06F 8/751 (20130101)
G06F 16/9024 (20190101) Original (OR) Class
G06F 21/563 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/084 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11934929 Woodbury
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Neal Woodbury (Tempe, Arizona)
ABSTRACT Methods and systems, including those employing machine learning, utilizing one or more algorithms for relating the structure of a molecule in a library to its function are described. Embodiments described herein relate structure to function by considering the covalent structure of the molecule, the components of that structure that are common to many molecules in the library, and the properties of those components as they relate to the function in question. Applications include, for example, enhancement and amplification of the diagnostic and prognostic signals provided by peptide arrays for use in analyzing the profile of antibodies in the blood produced in response to a disease, condition or treatment.
FILED Tuesday, October 26, 2021
APPL NO 17/510517
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 20/10 (20190101) Original (OR) Class

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 5/00 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935082 Cranshaw et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Justin Cranshaw (Pittsburgh, Pennsylvania);  Raz Schwartz (New York, New York);  Jason I. Hong (Pittsburgh, Pennsylvania);  Norman Sadeh-Koniecpol (Pittsburgh, Pennsylvania)
ABSTRACT Computer-based systems and methods for discovering neighborhood clusters in a geographic region, where the clusters have a mix of venues and are determined based on venue check-in data. The mix of venues for the clusters may be based on the social similarity between pairs of venues; or emblematic of certain neighborhood typologies; or emblematic of temporal check-in pattern types; or combinations thereof. The neighborhood clusters that are so discovered through venue-check in data could be used for many commercial and civic purposes.
FILED Monday, January 10, 2022
APPL NO 17/572252
ART UNIT 3624 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 30/0205 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935288 Connary et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Pointivo Inc. (Atlanta, Georgia)
ASSIGNEE(S) Pointivo Inc. (Atlanta, Georgia)
INVENTOR(S) Iven Connary (Atlanta, Georgia);  Guy Ettinger (Flowery Branch, Georgia);  Habib Fathi (Atlanta, Georgia);  Jacob Garland (Peachtree Corners, Georgia);  Daniel Ciprari (Atlanta, Georgia)
ABSTRACT The systems and methods herein provide improved methodologies for visualization on a user's display of sensor data (e.g., 2D and 3D information obtained from or derived from sensors) for objects, components, or features of interest in a scene. The previously acquired sensor data is processable for concurrent display of objects/features/scene or location visualizations to a user during their real-time navigation of a scene camera during a variety of user visualization activities. Sensor data can be acquired via the operation of vehicles configured with one or more sensors, such as unmanned aerial vehicles, or from other methodologies, or from any other suitable sensor data acquisition activities. Objects etc. for which acquired sensor data can be visualized by a user on a display includes buildings, parts of buildings, and infrastructure elements, among other things. The improved display of information to a user for visualization and information generation therefrom provides significant benefits over prior art display methodologies and exhibits notable utility for user activities such as, inspection, condition assessment, performance assessment, insurance applications, construction, inventorying, building information modeling, asset management and the like. Information derivable from the methodologies herein can be used for machine learning libraries and digital twin processes.
FILED Monday, January 03, 2022
APPL NO 17/567347
ART UNIT 2671 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory
CURRENT CPC
Systems for Controlling or Regulating Non-electric Variables
G05D 1/0016 (20130101)
G05D 1/0044 (20130101)
G05D 1/101 (20130101)

Image or Video Recognition or Understanding
G06V 20/10 (20220101)
G06V 20/176 (20220101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935810 Huitink et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Fayetteville, Arkansas)
ASSIGNEE(S) Board Of Trustees Of The University Of Arkansas (Little Rock, Arkansas)
INVENTOR(S) David Huitink (Prairie Grove, Arkansas);  John Harris (Rogers, Arkansas)
ABSTRACT A microelectronic device and method of making the same including a substrate and at least one expansion layer that adds stress to the substrate when said substrate expands.
FILED Thursday, May 06, 2021
APPL NO 17/313861
ART UNIT 1781 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 9/041 (20130101)
B32B 2307/30 (20130101)
B32B 2457/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/4882 (20130101)
H01L 23/562 (20130101)
H01L 23/3735 (20130101) Original (OR) Class
H01L 24/24 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/24942 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935843 Kozicki
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) Michael Kozicki (Phoenix, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Michael Kozicki (Phoenix, Arizona)
ABSTRACT Systems for physical unclonable function (“PUF”) generation, PUF devices, and methods for manufacturing PUF devices. In one implementation, the system includes a plurality of PUF devices and an electronic controller. Each of the plurality of PUF devices include a first electrochemically-inactive electrode, a second electrochemically-inactive electrode, and a layer of silicon suboxide. The layer of silicon suboxide is positioned directly between the first electrochemically-inactive electrode and the second electrochemically-inactive electrode. The electronic controller is communicably coupled to the plurality of PUF devices. The electronic controller is configured to read binary values associated with the plurality of PUF devices.
FILED Friday, December 04, 2020
APPL NO 17/112668
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/482 (20130101)
H01L 23/573 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/3278 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935938 Shen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Pin-Chun Shen (Changhua, Taiwan);  Jing Kong (Winchester, Massachusetts)
ABSTRACT Devices, such as transistors, that use bismuth to create ohmic contacts are provided, as are methods of manufacturing the same. The transistors, such as field-effect transistors, can include one or more two-dimensional materials, and electrical contact areas can be created on the two-dimensional material(s) using bismuth. The bismuth can help to provide energy-barrier free, ohmic contacts, and the resulting devices can have performance levels that rival or exceed state-of-the-art devices that utilize three-dimensional materials, like silicon. The two-dimensional materials can include transition metal dichalcogenides, such as molybdenum disulfide.
FILED Thursday, May 13, 2021
APPL NO 17/320183
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/45 (20130101)
H01L 29/4983 (20130101) Original (OR) Class
H01L 29/66628 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935975 Kelley et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina)
ASSIGNEE(S) UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina)
INVENTOR(S) Mathew Kelley (Columbia, South Carolina);  Andrew B. Greytak (Columbia, South Carolina);  Mvs Chandrashekhar (Lexington, South Carolina);  Joshua Letton (Columbia, South Carolina)
ABSTRACT The present disclosure is directed to methods for producing a photovoltaic junction that can include coating a bare junction with a composition. In one embodiment, the composition includes a plurality of quantum dots to create a film; exposing the film to a ligand to create a first layer; coating the first layer with the composition to form a film on the first layer; and exposing the film on the first layer to the ligand to create a second layer.
FILED Monday, December 05, 2022
APPL NO 18/074665
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/07 (20130101)
H01L 31/18 (20130101)
H01L 31/108 (20130101)
H01L 31/0312 (20130101)
H01L 31/0324 (20130101)
H01L 31/0336 (20130101)
H01L 31/1848 (20130101)
H01L 31/03048 (20130101)
H01L 31/022408 (20130101)
H01L 31/035218 (20130101) Original (OR) Class

Organic electric solid-state devices
H10K 30/00 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11936082 El Amili et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
Multidisciplinary University Research Initiative (MURI)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Library of Medicine (NLM)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computing and Communication Foundations (CCF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Division of Electrical, Communications and Cyber Systems (ECCS)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Abdelkrim El Amili (La Jolla, California);  Yeshaiahu Fainman (La Jolla, California);  Cheng-Yi Fang (La Jolla, California);  Hung-Hsi Lin (La Jolla, California)
ABSTRACT Microwave photonic devices use light to carry and process microwave signals over a photonic link. Light can be used as a stimulus to microwave devices that directly control microwave signals. Previous optically controlled devices suffer from large footprint, high optical power level required for switching, lack of scalability and complex integration requirements, restricting their implementation in practical microwave systems. Disclosed are monolithic optically reconfigurable integrated microwave switches (MORIMSs) built on a CMOS compatible silicon photonic chip. The disclosed scalable micrometer-scale switches provide higher switching efficiency and operate using optical power that is orders of magnitude lower than previous devices. The disclosed devices and techniques provide examples of silicon photonic platforms integrating microwave circuitry.
FILED Friday, August 28, 2020
APPL NO 17/006761
ART UNIT 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/011 (20130101)
G02F 1/21 (20130101)
G02F 1/212 (20210101)
G02F 1/0338 (20130101)
G02F 2201/16 (20130101)
G02F 2203/055 (20130101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 1/15 (20130101) Original (OR) Class
H01P 3/00 (20130101)
H01P 3/003 (20130101)
H01P 3/16 (20130101)
H01P 5/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11937372 Kramer-Bottiglio et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (, None)
INVENTOR(S) Rebecca Kramer-Bottiglio (Hamden, Connecticut);  Shanliangzi Liu (New Haven, Connecticut);  Dylan Shah (New Haven, Connecticut);  Lina Mercedes Sanchez Botero (New Haven, Connecticut)
ABSTRACT A biphasic composition comprises a quantity of liquid GaIn and a plurality of solid particles of Ga2O3 suspended in the quantity of liquid GaIn, the Ga2O3 particles having a median particle size between 8 μm and 25 μm, wherein the volumetric ratio of solid particles of Ga2O3 to liquid GaIn is between 0.4 and 0.7. A method of making a biphasic composition of GaIn, a method of making a stretchable circuit board assembly, and a stretchable circuit board assembly are also described.
FILED Thursday, June 24, 2021
APPL NO 17/357060
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/02 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/0283 (20130101)
H05K 1/0393 (20130101) Original (OR) Class
H05K 3/4635 (20130101)
H05K 2201/0233 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11931416 Blake et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Tim R. Blake (Palo Alto, California);  Paul Wender (Palo Alto, California);  Robert M. Waymouth (Palo Alto, California);  Ronald Levy (Palo Alto, California);  Ole Audun Werner Haabeth (Palo Alto, California);  Rebecca McClellan (Palo Alto, California);  Adrienne Sallets (Palo Alto, California)
ABSTRACT There are provided herein, inter alia, cationic amphipathic polymers, complexes, and compositions comprising same, and methods for their use including for the delivery of therapeutic, diagnostic and imaging agents, including nucleic acids, into a cell. The complexes, compositions and methods may facilitate delivery and targeted release of the therapeutic, diagnostic and imaging agents to particular cell types and tissues.
FILED Friday, January 31, 2020
APPL NO 17/427362
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/007 (20130101)
A61K 47/549 (20170801)
A61K 47/593 (20170801) Original (OR) Class
A61K 48/0041 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/08 (20130101)
C08G 63/64 (20130101)
C08G 63/685 (20130101)
C08G 73/028 (20130101)
C08G 73/0293 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931692 Voskian et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Verdox, Inc (Woburn, Massachusetts)
ASSIGNEE(S) VERDOX, INC (Woburn, Massachusetts)
INVENTOR(S) Sahag Voskian (Boston, Massachusetts);  Alexander Reath (Melrose, Massachusetts);  Cameron Rogers (Malden, Massachusetts);  Alexander Murray (Arlington, Massachusetts);  Seokjoon Oh (Malden, Massachusetts)
ABSTRACT A method for separating a Lewis acid gas from a fluid mixture, comprising contacting the fluid mixture with a reduced electroactive species; a non-aqueous electrolyte; and a stabilizing additive to form an anion adduct between the Lewis acid gas and the reduced electroactive species, wherein the electroactive species comprises an oxidized state, and at least one reduced state that bonds with the Lewis acid gas to form the anion adduct, wherein the stabilizing additive comprises a cationic Lewis acid, a hydrogen-bond donor, or a combination thereof, and the stabilizing additive is present in an effective amount to kinetically favor the forming of the anion adduct from the reduced electroactive species and thermodynamically favor the forming of the anion adduct in the thermodynamic equilibrium between the anion adduct and the reduced electroactive species.
FILED Monday, February 07, 2022
APPL NO 17/665815
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/326 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931805 Hildreth et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) Colorado School of Mines (Golden, Colorado)
ASSIGNEE(S) Colorado School of Mines (Golden, Colorado)
INVENTOR(S) Owen J. Hildreth (Lakewood, Colorado);  Subbarao Raikar (Golden, Colorado)
ABSTRACT A process is provided to remove a selective amount of material from a metal part fabricated by additive manufacturing in a self-terminating manner. The process can be used to remove support structures and trapped powder from a metal part as well as to smooth surfaces of a 3D printed metal part. In one embodiment, selected surfaces of the metal part are treated to make the selected surfaces at least one of mechanically and chemically unstable. The unstable portion of the metal support can then be removed chemically, electrochemically, with a pressure differential, and/or through vapor-phase etching. In one embodiment, the metal part may comprise one or more of an aluminum alloy, a titanium alloy, and a copper alloy. The process can be used to modify any fluid or vapor-accessible regions and surfaces of a 3D printed metal part.
FILED Monday, December 07, 2020
APPL NO 17/247275
ART UNIT 1738 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/43 (20210101) Original (OR) Class
B22F 10/62 (20210101)
B22F 10/64 (20210101)
B22F 2301/10 (20130101)
B22F 2301/052 (20130101)
B22F 2301/205 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 40/20 (20200101)
B33Y 70/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11931950 Howell et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (, California)
INVENTOR(S) Brian Howell (Livermore, California);  Brian Giera (Oakland, California);  Maxwell Murialdo (Westminster, California);  Kyle Sullivan (Brentwood, California)
ABSTRACT Systems and methods for controlling a material extrusion device to extrude a filament of an ink are provided. An extrusion printing control system collects from one or more sensors measurements representing an internal state of material extrusion processing during extrusion of the filament. In addition, the system collects an image of the filament as the filament is extruded. The system applies a classifier to the collected image to generate an image-derived state characterizing the filament. Based on the internal state and the image-derived state, the system estimates a derived state using a model. The system determines control parameters using the model to achieve a desired quality of the filament by minimizing a cost function based on the internal state, the image-derived state, the derived state, and constraints of the material extrusion device. Finally, the system provides the control parameters to a controller of the material extrusion device.
FILED Thursday, September 05, 2019
APPL NO 16/562253
ART UNIT 2128 — AI & Simulation/Modeling
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/106 (20170801) Original (OR) Class
B29C 64/393 (20170801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 50/02 (20141201)

Electric Digital Data Processing
G06F 18/24 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/02 (20130101)
G06N 3/008 (20130101)
G06N 20/00 (20190101)

Image or Video Recognition or Understanding
G06V 10/82 (20220101)
G06V 10/454 (20220101)
G06V 10/764 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932752 Hersam et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
INVENTOR(S) Mark C. Hersam (Wilmette, Illinois);  Ana Carolina Mazarin de Moraes (Chicago, Illinois)
ABSTRACT A composite film usable as a separator of an electrochemical device includes hBN nanosheets and at least one polymer. The hBN nanosheets are uniformly dispersed within a matrix of said least one polymer to achieve a highly porous microstructure. Said at least one polymer comprises one or more electrically insulating and electrochemically inert polymers.
FILED Friday, July 24, 2020
APPL NO 17/626602
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/04 (20130101)
C08K 3/38 (20130101)
C08K 9/02 (20130101) Original (OR) Class
C08K 2003/385 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932896 Yoshida et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Erika Yoshida (Tokyo, Japan);  Taek Soon Lee (Berkeley, California)
ABSTRACT The present invention provides for a composition comprising: (a) a first host cell capable of producing L-DOPA; and (b) a modified host cell is capable of converting L-DOPA into hydroxytyrosol (HTy); wherein any one or both of the first host cell and second host cell is a genetically modified host cell.
FILED Wednesday, December 26, 2018
APPL NO 16/232614
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/52 (20130101)
C12N 2510/02 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/22 (20130101) Original (OR) Class
C12P 13/22 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932923 Luo et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Alan Luo (Columbus, Ohio);  Emre Cinkilic (Columbus, Ohio);  Michael Moodispaw (Columbus, Ohio)
ABSTRACT Disclosed are aluminum alloys with high iron content and methods of making and using.
FILED Wednesday, September 29, 2021
APPL NO 17/489038
ART UNIT 1738 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Alloys
C22C 1/026 (20130101)
C22C 21/02 (20130101) Original (OR) Class

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/043 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933204 Koci et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Caterpillar Inc. (Peoria, Illinois)
ASSIGNEE(S) Caterpillar Inc. (Peoria, Illinois)
INVENTOR(S) Chad Palmer Koci (Washington, Illinois);  Kenth I. Svensson (Peoria, Illinois);  Eric Donald Wiebrecht (Germantown Hills, Illinois);  Venkatesan Veeriah (Chennai, India);  Qingzhong Li (Peoria, Illinois);  Suresh Babu Chennagowni (Peoria, Illinois)
ABSTRACT An engine component comprises one or more thermal barrier coatings applied to one or more areas of the engine component. The thermal barrier coatings reduce the temperature rate of change of the areas to which the thermal barrier coating is applied. Reducing the temperature rate of change can help reduce lattice structure damage caused by different temperatures in different areas of the engine component. The thermal barrier coating can be applied as a monolithic layer on a surface of the engine component or can be applied in different areas using patterns. The patterns allow for the tuning of the performance characteristics (temperature rate of change) of the areas of the engine component and can help reduce defect propagation, such as cracks, in the thermal barrier coating from one area of the thermal barrier coating to other areas of the thermal barrier coating.
FILED Thursday, June 23, 2022
APPL NO 17/848076
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 26/00 (20130101)

Cyclically Operating Valves for Machines or Engines
F01L 3/04 (20130101) Original (OR) Class
F01L 2301/00 (20200501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933299 Wilson et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Air Squared, Inc. (Thornton, Colorado)
ASSIGNEE(S) Air Squared, Inc. (Thornton, Colorado)
INVENTOR(S) John P. D. Wilson (Denver, Colorado);  Nathan D. Nicholas (Westminster, Colorado)
ABSTRACT A dual-drive co-rotating scroll device includes a housing; a first scroll rotatably mounted within the housing via a first cylindrical extension and a first plurality of bearings, and having a first axis of rotation; and a second scroll rotatably mounted within the housing via a second cylindrical extension and a second plurality of bearings, and having a second axis of rotation different than the first axis of rotation. At least one of the first cylindrical extension and the second cylindrical extension may comprise a plurality of permanent magnets and operate as a rotor of a first motor. An Oldham ring may be positioned between the first scroll and the second scroll and configured to maintain a relative angular position between the first scroll and the second scroll.
FILED Monday, October 24, 2022
APPL NO 17/972165
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps
F04C 18/023 (20130101) Original (OR) Class
F04C 29/02 (20130101)
F04C 29/0085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933675 Montgomery et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Jeffrey Montgomery (Livermore, California);  Magnus Lipp (Livermore, California)
ABSTRACT The present disclosure relates to a system for sensing temperature changes on a microsecond scale. The system uses a multi-channel pyrometer that works in the NIR spectrum to receive thermal radiation. Each channel includes an interference filter tuned to pass thermal radiation within a specified wavelength range, and a detector. Each detector detects thermal radiation focused on it. Each channel further includes an interference filter which reflects thermal radiation which does not pass through it to a subsequent downstream interference filter of a subsequent channel. Each subsequent interference filter is oriented to reflect the thermal radiation not passing through it to a next downstream one of the subsequent interference filters. A subsystem is included for receiving the output from the detectors and determining sensed temperature data therefrom, allowing measurement of temperatures down to 800 K.
FILED Monday, June 03, 2019
APPL NO 16/429888
ART UNIT 2896 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/20 (20130101)
G01J 5/53 (20220101)
G01J 5/0802 (20220101)
G01J 5/0803 (20130101)
G01J 5/0831 (20130101) Original (OR) Class
G01J 5/0879 (20220101)
G01J 2005/202 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933723 Mallery et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) REBELLION PHOTONICS, INC. (Houston, Texas)
ASSIGNEE(S) REBELLION PHOTONICS, INC. (Houston, Texas)
INVENTOR(S) Ryan Mallery (Houston, Texas);  Ohad Israel Balila (Friendswood, Texas);  Robert Timothy Kester (Friendswood, Texas)
ABSTRACT An infrared (IR) imaging system for determining a concentration of a target species in an object is disclosed. The imaging system can include an optical system including a focal plane array (FPA) unit behind an optical window. The optical system can have components defining at least two optical channels thereof, said at least two optical channels being spatially and spectrally different from one another. Each of the at least two optical channels can be positioned to transfer IR radiation incident on the optical system towards the optical FPA. The system can include a processing unit containing a processor that can be configured to acquire multispectral optical data representing said target species from the IR radiation received at the optical FPA. One or more of the optical channels may be used in detecting objects on or near the optical window, to avoid false detections of said target species.
FILED Thursday, April 27, 2023
APPL NO 18/308521
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/0806 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/314 (20130101)
G01N 21/3504 (20130101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 5/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933734 Launiere et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Cari A. Launiere (Bolingbrook, Illinois);  Nathaniel C. Hoyt (Clarendon Hills, Illinois)
ABSTRACT A flow cell system includes a vessel and a fluid located in the vessel. A fluid surface of the fluid can be vented to a first gas pressure. The fluid surface can have a first cross-sectional area. The flow cell system includes a conduit in fluid communication with the vessel and positioned downstream of the vessel. The conduit can have a region that includes one or more orifices and has a second cross-sectional area. The second cross-sectional area can be less than the first cross-sectional area. The one or more orifices can be vented to a second gas pressure. The second gas pressure can be equal to or greater than the first gas pressure. Methods for analyzing a process fluid can include characterizing the fluid in the conduit.
FILED Thursday, June 17, 2021
APPL NO 17/351010
ART UNIT 2896 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/38 (20130101)
G01N 21/31 (20130101)
G01N 21/85 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933758 Burge et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Scott R. Burge (Tempe, Arizona);  Russell G. Burge (Mountain View, California);  David A. Hoffman (Tempe, Arizona)
ASSIGNEE(S)
INVENTOR(S) Scott R. Burge (Tempe, Arizona);  Russell G. Burge (Mountain View, California);  David A. Hoffman (Tempe, Arizona)
ABSTRACT Methods and systems for monitoring microbial activity and microbial communication in an environment are disclosed. Exemplary methods include measuring a high impedance voltage between a reference electrode and one or more measurement electrodes to monitor microbial activity. Microorganisms form a biofilm that attaches to at least one of the one or more inert measurement electrodes and that allows for measuring the microbial activity, characterizing the environment, and/or monitoring microbial communication in the environment.
FILED Thursday, July 02, 2020
APPL NO 16/920196
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/327 (20130101)
G01N 27/4035 (20130101)
G01N 27/4163 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933782 Bearinger
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Jane P. Bearinger (Berwyn, Pennsylvania)
ABSTRACT Detector systems are described, based on a primary binding compound and a secondary binding compound used in combination with a support to detect a target in a sample. The detection systems include a liquid medium hosting a first binding compound specific to a target, the first binding compound comprising a label; and a solid medium hosting a second binding compound specific to the target, the second binding compound being different from and non-competitive with respect to the first binding compound.
FILED Tuesday, August 15, 2017
APPL NO 15/677961
ART UNIT 1677 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 2317/32 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)
G01N 33/54306 (20130101)
G01N 33/54366 (20130101)
G01N 33/54388 (20210801) Original (OR) Class
G01N 33/54389 (20210801)
G01N 2470/06 (20210801)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 435/97 (20130101)
Y10S 435/973 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11934331 Blagodurov et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Sergey Blagodurov (Bellevue, Washington);  Antonio Maria Franques Garcia (Urbana, Illinois)
ABSTRACT Systems, apparatuses, and methods for dynamically selecting between wired and wireless interconnects for sending packets are disclosed. A system includes at least a hybrid communication engine and a plurality of interconnects for connecting to various end-points. The communication engine dynamically discovers and utilizes the best interconnect technology available in between given end-points. The communication engine dynamically chooses the physical interconnect that is best suited at any given time to send data from one source to one or multiple destinations. This communication can be either on-chip or across nodes. The communication engine makes a decision based on a set of predetermined parameters that can be re-adjusted by the application layer, such as latency of the transmission, message data size, physical distance from source to destination, the energy cost, and the current congestion on the alternative interconnects.
FILED Monday, September 30, 2019
APPL NO 16/588612
ART UNIT 2416 — Multiplex and VoIP
CURRENT CPC
Electric Digital Data Processing
G06F 13/4027 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 12/46 (20130101)
H04L 45/02 (20130101)
H04L 47/28 (20130101)

Wireless Communication Networks
H04W 28/0221 (20130101)
H04W 40/10 (20130101)
H04W 72/30 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935662 Long et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
APPLICANT(S) WESTINGHOUSE ELECTRIC COMPANY LLC (Cranberry Township, Pennsylvania)
ASSIGNEE(S) Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania)
INVENTOR(S) Yun Long (Allison Park, Pennsylvania);  Peng Xu (Columbia, South Carolina);  Edward J. Lahoda (Edgewood, Pennsylvania)
ABSTRACT An elongate fuel element is described that has a silicon carbide cladding enclosing a fuel, such as UO2, wherein the fuel is dimensioned relative to the cladding to define gaps at each lateral end of the enclosure sufficiently large such that upon swelling in use, the fuel does not increase the strain on the cladding beyond the limits of the claddings strain tolerance. The lateral gaps at the ends of the fuel allow lateral expansion during swelling that reduces the strain on the cladding.
FILED Tuesday, July 02, 2019
APPL NO 16/459764
ART UNIT 3619 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Nuclear Reactors
G21C 3/07 (20130101)
G21C 3/16 (20130101)
G21C 3/38 (20130101) Original (OR) Class
G21C 3/047 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11936004 Lopes et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Pietro Papa Lopes (Woodridge, Illinois);  Timothy Fister (Oak Park, Illinois);  Susan J. Babinec (Midland, Michigan);  Vojislav Stamenkovic (Naperville, Illinois)
ABSTRACT An electrochemical cell includes a housing, a positive electrode substrate disposed within a first electrode chamber of the housing, a negative electrode substrate disposed within a second electrode chamber of the housing, and a separator may be disposed within the housing between the first electrode chamber and the second electrode chamber. A method further includes pumping a manufacturing electrolyte through the positive electrode portion around the positive electrode substrate. The method further includes applying a first electrical signal to the positive electrode substrate so as to electrochemically fabricate one or both of an active material the negative electrode substrate to form a negative electrode and/or an active material on the positive electrode substrate, thereby forming a positive electrode.
FILED Friday, January 28, 2022
APPL NO 17/587644
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/44 (20130101)
H01M 10/128 (20130101)
H01M 10/4242 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11936185 Nguyen et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Tu Anh Nguyen (Albuquerque, New Mexico);  Raymond H. Byrne (Albuquerque, New Mexico);  Babu Chalamala (Albuquerque, New Mexico);  David G. Wilson (Tijeras, New Mexico)
ABSTRACT Systems and methods for Energy Storage-based Packetized Delivery of Electricity (ES-PDE) are disclosed that are radically different from the operation of today's grid. Using ES-PDE, the loads are powered by the energy storage systems (ESS) the majority of the time and only receive packets of electricity periodically to charge the ESSs. Therefore, the grid operators can schedule the delivery of electricity packets to utilize the existing grid infrastructure. Since the customers are powered by the co-located ESSs they are not impacted by the grid operation in short term. Therefore, when grid outages occur, the customers still have power for some time, giving the grid more time to be fully restored.
FILED Thursday, September 01, 2022
APPL NO 17/901497
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/32 (20130101)
H02J 3/0075 (20200101) Original (OR) Class
H02J 3/381 (20130101)
H02J 2300/24 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11936199 Pries et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Jason L. Pries (Oak Ridge, Tennessee);  Veda Prakash Galigekere (Oak Ridge, Tennessee);  Gui-Jia Su (Oak Ridge, Tennessee)
ABSTRACT Polyphase wireless power transfer systems are provided. The transfer system may be used for charging hybrid and electric vehicles. The systems are capable of transferring over 50 KW over an air gap of 15 cm. The systems use a rotating magnetic field to transfer power. The system may comprise transmitter coil assembly. The coil assembly may be one or more layers. The system may employ either unipolar or bipolar coils. The transmitter also comprises compensating capacitance connected in series with at least one coil for each phase. A value of the compensating capacitance for each phase is determined such that the transmitter has at least two independently excitable resonant modes at a resonant frequency. The transmitter is compatible with a plurality of different receivers including three-phase, single phase with a circular coil and single phase with DD coils.
FILED Thursday, January 02, 2020
APPL NO 17/420486
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 27/38 (20130101)
H01F 38/14 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/12 (20160201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11936246 Simizu et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania)
INVENTOR(S) Satoru Simizu (Pittsburgh, Pennsylvania);  Paul Richard Ohodnicki, Jr. (Allison Park, Pennsylvania);  Michael Edward McHenry (Pittsburgh, Pennsylvania)
ABSTRACT Provided is an axial flux motor including a rotor having a wound ribbon core, the wound ribbon core including a metal amorphous nanocomposite material. The axial flux motor further includes a stator assembly spaced apart from the rotor along a rotation axis of the rotor. The stator assembly includes a body including a metal amorphous nanocomposite material and a plurality of permanent magnets substantially free of rare-earth materials. The plurality of permanent magnets is arranged on the body of the stator assembly.
FILED Friday, January 03, 2020
APPL NO 16/733593
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Dynamo-electric Machines
H02K 1/02 (20130101)
H02K 1/2796 (20220101) Original (OR) Class
H02K 3/12 (20130101)
H02K 19/10 (20130101)
H02K 21/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11937363 Kobernik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Energy (DOE)
APPLICANT(S) SHINE Technologies, LLC (Janesville, Wisconsin)
ASSIGNEE(S) SHINE Technologies, LLC (Janesville, Wisconsin)
INVENTOR(S) Arne Kobernik (Monona, Wisconsin);  Carl Sherven (Monona, Wisconsin);  Casey Lamers (Monona, Wisconsin);  Chris Seyfert (Monona, Wisconsin);  Evan Sengbusch (Monona, Wisconsin);  Gabriel Becerra (Monona, Wisconsin);  Jin Lee (Monona, Wisconsin);  Logan Campbell (Monona, Wisconsin);  Mark Thomas (Monona, Wisconsin);  Michael Taylor (Monona, Wisconsin);  Preston Barrows (Monona, Wisconsin);  Ross Radel (Monona, Wisconsin);  Tye Gribb (Monona, Wisconsin)
ABSTRACT Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes.
FILED Monday, January 09, 2023
APPL NO 18/094726
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 37/08 (20130101)
H01J 37/32082 (20130101)
H01J 41/04 (20130101)
H01J 41/14 (20130101)

Spark Gaps; Overvoltage Arresters Using Spark Gaps; Sparking Plugs; Corona Devices; Generating Ions to be Introduced into Non-enclosed Gases
H01T 23/00 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 31/26 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/46 (20130101)
H05H 1/54 (20130101)
H05H 1/4622 (20210501)
H05H 3/06 (20130101)
H05H 5/04 (20130101)
H05H 6/00 (20130101)
H05H 7/22 (20130101) Original (OR) Class
H05H 9/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11932581 Agarwal et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Arvind Agarwal (Miami, Florida);  Kazue Orikasa (Miami, Florida);  Tyler Dolmetsch (Miami, Florida);  Tony Thomas (Miami, Florida)
ASSIGNEE(S) THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida)
INVENTOR(S) Arvind Agarwal (Miami, Florida);  Kazue Orikasa (Miami, Florida);  Tyler Dolmetsch (Miami, Florida);  Tony Thomas (Miami, Florida)
ABSTRACT Foams and methods of fabricating and using the same are provided. The foams can be three-dimensional (3D), free-standing, and/or rigid and can be used as, for example, nanofiller networks. The shape and size of the foam pore interconnected network can be tailorable/tailored. The foams can be, for example, hybrid one-dimensional (1D)/two-dimensional (2D) foams of 1D and 2D materials (e.g., hybrid boron nitride nanotube (BNNT)/boron nitride nanoplatelet (BNNP) foams). A freeze-drying-based method can be used to fabricate bulk porous foam, which can be used for, e.g., nanofiller for polymer nanocomposites.
FILED Wednesday, August 23, 2023
APPL NO 18/454169
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/0091 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/80 (20130101) Original (OR) Class
C04B 35/62655 (20130101)
C04B 38/0605 (20130101)
C04B 41/48 (20130101)
C04B 41/0072 (20130101)
C04B 41/83 (20130101)
C04B 41/4535 (20130101)
C04B 2235/386 (20130101)
C04B 2235/606 (20130101)
C04B 2235/5284 (20130101)
C04B 2235/5292 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/005 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 2003/385 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932897 Warriner et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Logan W. Warriner (Lexington, Kentucky);  Daniel W. Pack (Lexington, Kentucky)
ABSTRACT A method of making curcuminoids in a mammalian cell. The method of making a curcuminoid in a mammalian cell includes expressing one or more enzymes in the mammalian cell, the enzymes being selected from the group consisting of tyrosine ammonia lyase (TAL), 4-coumaroyl-CoA ligase (4CL1), curcuminoid synthase (CUS), diketide-CoA synthase (DCS), curcumin synthase (CURS1), 4-coumarate 3-hydroxylase (C3H), caffeoyl-CoA 3-O-methyltransferase (CCoAMT), and acetyl-CoA carboxylase (ACC). The expressing of the one or more enzymes converts a starting material, such as tyrosine or ferulic acid, to the curcuminoid. Also provided herein are therapeutic uses for the curcuminoid made in a mammalian cell.
FILED Wednesday, December 18, 2019
APPL NO 16/719843
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/22 (20130101)
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/10 (20130101)
C12N 5/0686 (20130101)
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 15/85 (20130101)
C12N 2310/20 (20170501)
C12N 2510/00 (20130101)
C12N 2800/80 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/26 (20130101) Original (OR) Class

Enzymes
C12Y 114/14 (20130101)
C12Y 201/01104 (20130101)
C12Y 203/01 (20130101)
C12Y 403/01023 (20130101)
C12Y 602/01012 (20130101)
C12Y 604/01002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935661 Jogerst et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
APPLICANT(S) BWXT Nuclear Energy, Inc. (Charlotte, North Carolina)
ASSIGNEE(S) BWXT Nuclear Energy, Inc. (Charlotte, North Carolina)
INVENTOR(S) James D. Jogerst (Forest, Virginia);  Eric A. Barringer (Rustburg, Virginia)
ABSTRACT CERMET fuel element includes a fuel meat of consolidated ceramic fuel particles (preferably refractory-metal coated HALEU fuel kernels) and an array of axially-oriented coolant flow channels. Formation and lateral positions of coolant flow channels in the fuel meat are controlled during manufacturing by spacer structures that include ceramic fuel particles. In one embodiment, a coating on a sacrificial rod (the rod being subsequently removed) forms the coolant channel and the spacer structures are affixed to the coating; in a second embodiment, a metal tube forms the coolant channel and the spacer structures are affixed to the metal tube. The spacer structures laterally position the coolant channels in spaced-apart relation and are consolidated with the ceramic fuel particles to form CERMET fuel meat of a fuel element, which are subsequently incorporated into fuel assemblies that are distributively arranged in a moderator block within a nuclear fission reactor, in particular for propulsion.
FILED Wednesday, August 11, 2021
APPL NO 17/399859
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/15 (20130101)
B22F 2301/20 (20130101)

Cosmonautics; Vehicles or Equipment Therefor
B64G 1/408 (20130101)

Alloys
C22C 1/05 (20130101)

Jet-propulsion Plants
F02K 7/02 (20130101)

Nuclear Reactors
G21C 3/64 (20130101)
G21C 5/02 (20130101)
G21C 5/12 (20130101)
G21C 21/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11937372 Kramer-Bottiglio et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (, None)
INVENTOR(S) Rebecca Kramer-Bottiglio (Hamden, Connecticut);  Shanliangzi Liu (New Haven, Connecticut);  Dylan Shah (New Haven, Connecticut);  Lina Mercedes Sanchez Botero (New Haven, Connecticut)
ABSTRACT A biphasic composition comprises a quantity of liquid GaIn and a plurality of solid particles of Ga2O3 suspended in the quantity of liquid GaIn, the Ga2O3 particles having a median particle size between 8 μm and 25 μm, wherein the volumetric ratio of solid particles of Ga2O3 to liquid GaIn is between 0.4 and 0.7. A method of making a biphasic composition of GaIn, a method of making a stretchable circuit board assembly, and a stretchable circuit board assembly are also described.
FILED Thursday, June 24, 2021
APPL NO 17/357060
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties
H01B 1/02 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/0283 (20130101)
H05K 1/0393 (20130101) Original (OR) Class
H05K 3/4635 (20130101)
H05K 2201/0233 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11931373 Dickey et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Veterans Health Administration (VHA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of South Florida (Tampa, Florida);  University of Kansas (Lawrence, Kansas)
ASSIGNEE(S) University of South Florida (Tampa, Florida);  University of Kansas (Lawrence, Kansas)
INVENTOR(S) Chad Dickey (Tampa, Florida);  Lindsey Shelton (Tampa, Florida);  Brian Blagg (Lawrence, Kansas);  John Koren (Tampa, Florida);  Laura Jenelle Blair (Tampa, Florida)
ABSTRACT Disclosed herein are compounds and methods for inhibiting Aha1 for the treatment of tauopathies and neurodegenerative diseases. The Aha1 inhibitor may reduce the interaction between Aha1 and Hsp90. The Aha1 inhibitor may reduce aggregation of tau protein. The Aha1 inhibitor may include a compound selected from KU-177, KU-174, and KU-308.
FILED Friday, April 15, 2022
APPL NO 17/722011
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/366 (20130101)
A61K 31/7048 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11932908 Delgado-Escueta et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California);  RIKEN (Saitama, Japan);  INSTITUTO NACIONAL DE NEUROLOGIA Y NEUROCIRUGIA MANUEL VELASCO SUAREZ (Delegacion Tlalpan, Mexico);  U.S. GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia);  Marco Tulio Medina-Hernandez (Los Angeles, California)
ASSIGNEE(S)
INVENTOR(S) Antonio V. Delgado-Escueta (Malibu, California);  Kazuhiro Yamakawa (Saitama, Japan);  Toshimitsu Suzuki (Saitama, Japan);  Marco Tulio Medina-Hernandez (Tegucigalpa, China PRC);  Maria Elisa Alonso Vilatela (Delegacion Coyoacan, Mexico)
ABSTRACT Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1, EFHC1 agonists, or EFHC1 analogs are provided. Compositions and methods for diagnosis or treatment of epilepsy disease with EFHC1a, EFHC1a agonists, or EFHC1a analogs are provided.
FILED Monday, February 08, 2021
APPL NO 17/248798
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/118 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/172 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11935235 Abramoff et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa)
ASSIGNEE(S) UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa);  UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Michael Abramoff (Iowa City, Iowa);  Gwenole Quellec (Brest, France)
ABSTRACT A method of identifying an object of interest can comprise obtaining first samples of an intensity distribution of one or more object of interest, obtaining second samples of an intensity distribution of confounder objects, transforming the first and second samples into an appropriate first space, performing dimension reduction on the transformed first and second samples, whereby the dimension reduction of the transformed first and second samples generates an object detector, transforming one or more of the digital images into the first space, performing dimension reduction on the transformed digital images, whereby the dimension reduction of the transformed digital images generates one or more reduced images, classifying one or more pixels of the one or more reduced images based on a comparison with the object detector, and identifying one or more objects of interest from the classified pixels.
FILED Thursday, September 01, 2022
APPL NO 17/901582
ART UNIT 2672 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory
CURRENT CPC
Electric Digital Data Processing
G06F 18/00 (20230101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/75 (20170101)
G06T 2207/10024 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/30041 (20130101)
G06T 2207/30096 (20130101)

Image or Video Recognition or Understanding
G06V 40/193 (20220101)
G06V 2201/03 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11931138 Tathireddy et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Applied Biosensors, LLC (Salt Lake City, Utah)
ASSIGNEE(S) Applied Biosensors, LLC (Salt Lake City, Utah)
INVENTOR(S) Prashant Tathireddy (Salt Lake City, Utah);  Rohit Sharma (Salt Lake City, Utah);  Seung Hei Cho (Salt Lake City, Utah);  Nicholas Frazier (Salt Lake City, Utah);  Yoonsung Goo (Salt Lake City, Utah)
ABSTRACT A hydrogel sensor device can include a crosslinked hydrogel body which changes in volume in response to an environmental stimulus, a support post positioned to mechanically support the crosslinked hydrogel body during the change in volume, and a sensor positioned to detect the change in volume in the crosslinked hydrogel body.
FILED Friday, December 14, 2018
APPL NO 16/221003
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/06 (20130101) Original (OR) Class
A61B 2562/04 (20130101)
A61B 2562/16 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/24 (20130101)
C08J 3/075 (20130101)

Compositions of Macromolecular Compounds
C08L 33/04 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/72 (20130101)
G01N 33/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11933749 Motes, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Materials and Manufacturing Directorate (MMD)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Texas Research International, Inc. (Austin, Texas)
ASSIGNEE(S) Texas Research International, Inc (Austin, Texas)
INVENTOR(S) Doyle T. Motes, III (Austin, Texas);  Marcus Keiser (Cedar Park, Texas);  Richard Piner (Austin, Texas)
ABSTRACT Non-destructive sensing methods and devices for inspection and measuring in manufacturing applications for removal of contaminants from composite surfaces coupled with sensing and activation of the composite surfaces.
FILED Friday, September 10, 2021
APPL NO 17/472533
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/225 (20130101)
G01N 23/2202 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11936766 Chornenky
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) NOKOMIS, INC. (Canonsburg, Pennsylvania)
ASSIGNEE(S) NOKOMIS, INC. (Canonsburg, Pennsylvania)
INVENTOR(S) Todd Eric Chornenky (Carmichaels, Pennsylvania)
ABSTRACT A receiver includes a circuit designed to process, based on a plurality of timed waveform reference locations, a waveform signal, the waveform signal comprising a message. The circuit may include a clock source, an input configured to receive the waveform signal, a time location reference circuit coupled to the clock source, the time location reference circuit designed to output the plurality of timed waveform reference locations, each timed waveform reference location being set by the clock, and a signal processing circuit coupled to the time location reference circuit, the signal processing circuit designed to generate an output voltage in a response to the waveform signal being inputted into the signal processing circuit through the input and processed at each timed waveform reference location from the series of timed waveform reference locations. A transmitter that generates the waveform signal can be also provided where the clocks are matched.
FILED Thursday, September 08, 2022
APPL NO 17/940493
ART UNIT 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Transmission
H04B 1/16 (20130101)
H04B 17/336 (20150115)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 7/0012 (20130101) Original (OR) Class
H04L 7/0037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Central Intelligence Agency (CIA) 

US 11936748 Cody et al.
FUNDED BY
Central Intelligence Agency (CIA)
APPLICANT(S) Censys, Inc. (Ann Arbor, Michigan)
ASSIGNEE(S) Censys, Inc. (Ann Arbor, Michigan)
INVENTOR(S) Jeff Cody (Huntertown, Indiana);  David Adrian (Denver, Colorado);  J. Alex Halderman (Ann Arbor, Michigan);  Paul A. Parkanzky (Ann Arbor, Michigan)
ABSTRACT Various embodiments of apparatuses and methods for a continuous scanning engine with automatic protocol detection are described. In some embodiments, the continuous scanning engine comprises one or more discovery components and one or more protocol detection components. The discovery components, in some embodiments, send initial packets to a plurality of ports of a plurality of network addresses of a network, receive responses to a least some of the initial packets, asynchronously match the received responses to the sent initial packets, and determine that some ports at some network addresses require further analysis. The protocol inspection components, in some embodiments, attempt to communicate with the ports at the network addresses using a plurality of communication protocols, determine that an attempted communication protocols results in a successful communication, and provides the port, the network address, and the attempted communication protocol that resulted in the successful communication to a database.
FILED Friday, October 29, 2021
APPL NO 17/515121
ART UNIT 2447 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 43/18 (20130101)
H04L 67/51 (20220501) Original (OR) Class
H04L 69/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11932557 Shi et al.
FUNDED BY
National Science Foundation (NSF)
Department of Agriculture (USDA)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
INVENTOR(S) Jian Shi (Lexington, Kentucky);  Wenqi Li (Lexington, Kentucky);  Jameson Hunter (Lexington, Kentucky);  Yuxuan Zhang (Lexington, Kentucky);  Qing Shao (Lexington, Kentucky)
ABSTRACT Methods for detecting and extracting plastic contaminants within a water sample, which involve introducing the water sample to a hydrophobic deep eutectic solvent, are provided.
FILED Tuesday, June 29, 2021
APPL NO 17/362515
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 11/0492 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/26 (20130101) Original (OR) Class
C02F 2101/34 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/94 (20130101)
G01N 33/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11933922 Schmidt et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Daniel Richard Schmidt (Boulder, Colorado);  Joel Calvin Weber (Boulder, Colorado)
ABSTRACT Hybrid subtractive-additive production of a superconducting multi-layer transition-edge sensor includes: forming a superconductor layer; forming a patterning photoresist on the superconductor layer; forming a sensor pattern in the patterning photoresist; subtractively forming, from the superconductor layer, the superconductor sensor layer; removing the patterning photoresist from the superconductor sensor layer; forming a template photoresist on the superconductor sensor layer; forming an inverse normal metal layer pattern in the template photoresist and exposing a bilayer portion of the superconductor sensor layer for addition of a normal metal layer; and additively forming the normal metal layer on the superconductor sensor layer such that the sensor pattern is interposed between the normal metal layer and the substrate.
FILED Friday, March 05, 2021
APPL NO 17/192943
ART UNIT 2882 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/16 (20130101) Original (OR) Class

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/0035 (20130101)

Electric solid-state devices not otherwise provided for
H10N 60/0128 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11934538 Eldefrawy et al.
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-ST)
APPLICANT(S) SRI International (Menlo Park, California)
ASSIGNEE(S) SRI INTERNATIONAL (Menlo Park, California)
INVENTOR(S) Karim Eldefrawy (Palo Alto, California);  Hassen Saidi (Palo Alto, California);  Michael E. Locasto (Lebanon, New Jersey);  Norrathep Rattanavipanon (Irvine, California)
ABSTRACT In general, this disclosure describes techniques for replacing target cryptographic primitives in executable binary files with other, potentially more secure, cryptographic primitives. In some examples, a computing system for augmenting cryptographic executables includes a locator to determine if an executable program in an executable binary file includes a target cryptographic primitive. The computing system can include a patch generator to generate patch instructions in response to a determination by the locator that the executable program includes the target cryptographic primitive. The patch instructions cause the executable program to execute a replacement cryptographic primitive instead of the target cryptographic primitive. A rewriter engine of the computing system can modify, based on the patch instructions, the executable program to generate a modified executable binary file.
FILED Friday, July 24, 2020
APPL NO 16/938664
ART UNIT 2499 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/30032 (20130101)
G06F 21/602 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Justice (DOJ) 

US 11933580 Vabnick et al.
FUNDED BY
Department of Justice (DOJ)
Federal Bureau of Investigation (FBI)
APPLICANT(S) Federal Bureau of Investigation (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as Represented by the Federal Bureau of Investigation, Department of Justice (Washington, District of Columbia)
INVENTOR(S) Ian B. Vabnick (Fredericksburg, Virginia);  Lee R. Foltz (Indian Head, Maryland);  Daniel E. McCarthy (La Plata, Maryland);  Marc J. La Belle (Buffalo, New York);  Michael S. Shattuck (Port Royal, Virginia)
ABSTRACT Provided herein are shaped charges for focusing a fluid mass and related methods of using the shaped charges for disruption of an explosive target with a spherical projectile. The shaped charge comprises a plastic shell having a special geometric shape configured to support a shape-conforming explosive. A cylindrical plastic body has an interior volume for containing a fluid and the plastic shell. The plastic body closed distal end has a geometric shape that is substantially matched to the shape of the plastic shell. Metal spherical projectiles having an outer layer of metal selected to have an effective density matched to the fluid provide advantageous target disruption capabilities.
FILED Monday, February 08, 2021
APPL NO 17/170304
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Weapons for Projecting Missiles Without Use of Explosive or Combustible Propellant Charge; Weapons Not Otherwise Provided for
F41B 9/0046 (20130101) Original (OR) Class

Explosive Charges, e.g for Blasting, Fireworks, Ammunition
F42B 1/028 (20130101)
F42B 1/032 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

European Union (EU) 

US 11933740 Valsesia et al.
FUNDED BY
European Union (EU)
APPLICANT(S) The European Union, represented by the European Commission (Brussels, Belgium)
ASSIGNEE(S) THE EUROPEAN UNION, REPRESENTED BY THE EUROPEAN COMMISSION (Brussels, Belgium)
INVENTOR(S) Andrea Valsesia (Ranco, Italy);  Grigore Rischitor (Brussels, Belgium);  Douglas Gilliland (Comabbio, Italy);  Jessica Ponti (Travedona Monate, Italy);  Francesco Fumagalli (Cassago in Brianza, Italy);  Monica Quarato (Noci, Italy);  Pascal Colpo (Angera, Italy);  Isaac Ojea Jimenez (Munich, Germany)
ABSTRACT The present invention relates to a method for the detection of at least one nano or micro plastic particle comprised in a heterogeneous matrix material comprising the following steps: applying of at least one part of a heterogeneous matrix material comprising at least one nano or micro plastic particle onto at least a portion of a surface of a conductive support thereby forming a first layer onto said surface, irradiating of at least a portion of said first layer with at least one ion beam, thereby forming an irradiated layer, detecting of the at least one nano or micro plastic particle comprised in said irradiated layer by a detection method chosen from the group of Raman nanoscopic techniques, or infrared nanoscopic techniques, or charge dependent detection methods or combination thereof. The present invention allowed good detection of micro and nano plastic particles with high resolution and sensitivity.
FILED Thursday, January 30, 2020
APPL NO 17/427421
ART UNIT 2881 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/2813 (20130101)
G01N 21/65 (20130101)
G01N 21/94 (20130101) Original (OR) Class
G01N 23/2251 (20130101)
G01N 33/442 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 11931166 Argenta et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S) Applied Research Associates, Inc. (Albuquerque, New Mexico)
ASSIGNEE(S) Applied Research Associates, Inc. (Albuquerque, New Mexico)
INVENTOR(S) Christopher Argenta (Albuquerque, New Mexico);  Aaron Williams (Albuquerque, New Mexico);  Greg Foderaro (Albuquerque, New Mexico);  Thomas Paniagua (Albuquerque, New Mexico)
ABSTRACT A system and method of generating an enhanced Lund and Browder chart and total body surface area burn score is described herein. In some embodiments, a plurality of images is obtained from of a patient using a camera system. The images may be taken by aligning the patient's body with pose templates presented on a display of the camera system. The non-skin portions of the images may be removed, and skin analysis performed on the skin portion to determine burn location, coverage, and depth. Further, landmarks may be detected in the images to morph and align the images with the pose templates to obtain standard poses. The plurality of images may be combined and presented in two-dimensional and three-dimensional models with labels and the total surface area burn score.
FILED Tuesday, July 07, 2020
APPL NO 16/922598
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0013 (20130101)
A61B 5/0075 (20130101)
A61B 5/0077 (20130101)
A61B 5/445 (20130101) Original (OR) Class
A61B 5/743 (20130101)
A61B 5/744 (20130101)
A61B 5/6898 (20130101)
A61B 5/7264 (20130101)
A61B 5/7282 (20130101)
A61B 2576/02 (20130101)

Image Data Processing or Generation, in General
G06T 7/0014 (20130101)
G06T 11/206 (20130101)
G06T 19/20 (20130101)
G06T 2219/2016 (20130101)

Image or Video Recognition or Understanding
G06V 10/42 (20220101)
G06V 10/44 (20220101)
G06V 10/143 (20220101)
G06V 20/20 (20220101)
G06V 2201/03 (20220101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 11934948 Ferguson-Walter et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) The Government of the United States as represented by the Director, National Security Agency (Fort George G. Meade, Maryland)
ASSIGNEE(S) The Government of the United States as represented by the Director, National Security Agency (, None)
INVENTOR(S) Kimberly J Ferguson-Walter (San Diego, California);  Sunny James Fugate (San Diego, California)
ABSTRACT An adaptive deception system is provided for defending a production network against cyber-attacks utilizing deception devices on the production network. The adaptive deception system includes a deception management system. The deception management system includes monitors for making observations regarding the deception devices including observations of an attacker's interaction with the deception device. The adaptive deception system further incudes a control system having sensors that receive the observations of the deception management system. The control system is configured to provide an adaption specification in response to the observations made. Actuators of the control system are activated in order to provide the adaption specification to the deception management system where monitors of the deception management system implement the specified adaption. Implementation of the adaption adapts the properties of the deception devices to interfere with the cyber-attacker.
FILED Wednesday, July 15, 2020
APPL NO 16/930046
ART UNIT 2491 — Cryptography and Security
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)
G06N 3/08 (20130101) Original (OR) Class

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1491 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 11933219 Amadon et al.
FUNDED BY
APPLICANT(S) RTX Corporation (Farmington, Connecticut)
ASSIGNEE(S) RTX CORPORATION (Farmington, Connecticut)
INVENTOR(S) Colin G. Amadon (Kennebunk, Maine);  Michael C. Firnhaber (East Hampton, Connecticut)
ABSTRACT A stator configuration for a gas turbine engine including: a splitter segment, the splitter segment extending from a forward end to a rearward end; a forward most first stator extending radially outwardly from the splitter segment, the forward most first stator being completely located downstream from the forward end of the splitter segment; and a forward most second stator extending radially inwardly from the splitter segment, the splitter segment, the forward most first stator and the forward most second stator being formed as a single, integrally formed structure, the forward most first stator positioned closer to the forward end relative to a distance between the forward most second stator and the forward end and the forward most second stator positioned closer to the rearward end relative to a distance between the forward most first stator and the rearward end.
FILED Monday, August 01, 2022
APPL NO 17/878653
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 7/04 (20130101) Original (OR) Class

Non-positive-displacement Pumps
F04D 19/002 (20130101)
F04D 29/545 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/36 (20130101)
F05D 2240/12 (20130101)
F05D 2260/606 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11934754 Kwon et al.
FUNDED BY
APPLICANT(S) KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (Seoul, South Korea)
ASSIGNEE(S) Korea Institute of Science and Technology (, South Korea)
INVENTOR(S) Hee Young Kwon (Seoul, South Korea);  Jun Woo Choi (Seoul, South Korea)
ABSTRACT Disclosed is a magnetic parameter value estimation method using deep learning, the magnetic parameter value estimation method including creating a simulated magnetic domain image corresponding to a spin configuration of a two-dimensional magnetic system created through computer simulation, modeling a deep neural network using the simulated magnetic domain image, and estimating a magnetic parameter value of an observed magnetic domain image using the modeled deep neural network.
FILED Friday, October 16, 2020
APPL NO 17/072384
ART UNIT 2146 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 30/27 (20200101) Original (OR) Class
G06F 2111/10 (20200101)

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)
G06N 3/08 (20130101)
G06N 3/045 (20230101)
G06N 5/01 (20230101)
G06N 7/01 (20230101)
G06N 20/00 (20190101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 7/0294 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, March 19, 2024.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240319.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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