FedInvent™ Patents
Patent Details for Tuesday, April 02, 2024
This page was updated on Tuesday, April 02, 2024 at 10:48 PM GMT
Department of Health and Human Services (HHS)
| US 11944216 | Pathak |
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| FUNDED BY |
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| APPLICANT(S) | Verily Life Sciences LLC (South San Francisco, California) |
| ASSIGNEE(S) | Verily Life Sciences LLC (South San Francisco, California) |
| INVENTOR(S) | Anupam Pathak (Los Altos, California) |
| ABSTRACT | A handheld system includes a housing, a motion-generating mechanism disposed within the housing, an attachment arm extending from the housing and having a first end coupled to the motion-generating mechanism and a second end configured to receive a user assistive device, a first sensor mounted to measure a first motion of the handheld system and generate a first signal indicative of the first motion, and a control system coupled to the motion-generating mechanism and the first sensor. The control system is configured to use the first signal to stabilize the user-assistive device and compensate for human tremors imparted to the housing. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 16/581660 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Household or Table Equipment A47G 21/02 (20130101) A47G 21/08 (20130101) Original (OR) Class A47G 2200/046 (20130101) Kitchen Equipment; Coffee Mills; Spice Mills; Apparatus for Making Beverages A47J 43/28 (20130101) Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/1101 (20130101) A61B 5/4082 (20130101) A61B 5/6887 (20130101) A61B 2562/0219 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/08 (20130101) A61F 4/00 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/00 (20130101) A61H 23/00 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 7/1005 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/021 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944317 | Maitland et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas); SHAPE MEMORY MEDICAL, INC. (Santa Clara, California) |
| ASSIGNEE(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas); SHAPE MEMORY MEDICAL, INC. (Santa Clara, California) |
| INVENTOR(S) | Duncan J. Maitland (College Station, Texas); Todd L. Landsman (San Jose, California); Jennifer N. Rodriguez (Fremont, California); Anthony J. Boyle (College Station, Texas); Alan C. Glowczwski (College Station, Texas); Mark A. Wierzbicki (College Station, Texas) |
| ABSTRACT | An embodiment includes a system comprising: an outer conduit; a shape memory polymer (SMP) foam; a metal backbone including: (a)(i) a first portion that extends from the SMP foam proximal end to the SMP foam distal end and which is generally covered by the SMP foam, and (a)(ii) a distal portion that extends distally from the SMP foam distal end and which is not covered by the SMP foam; wherein: (b)(i) SMP foam and the metal backbone are both included within the outer conduit adjacent to the outer conduit distal end; (b)(ii) the metal backbone distal portion transitions from a secondary shape that is uncoiled to a primary shape that is coiled; and (b)(iii) the metal backbone distal portion is in the metal backbone distal portion secondary shape and is located between the SMP foam distal end and the distal end of the outer conduit. |
| FILED | Wednesday, June 22, 2022 |
| APPL NO | 17/846449 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1215 (20130101) A61B 17/1219 (20130101) Original (OR) Class A61B 17/12109 (20130101) A61B 17/12172 (20130101) A61B 2017/00526 (20130101) A61B 2017/00871 (20130101) A61B 2017/00898 (20130101) A61B 2017/12063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944382 | Jia et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| INVENTOR(S) | Yali Jia (Portland, Oregon); Xiang Wei (Portland, Oregon) |
| ABSTRACT | Disclosed are methods and systems correcting bulk-motion artifacts in phase-based functional OCT images. The disclosed methods and systems are based on the use of the standard deviation of the phase shift signal present in phase-based OCT imaging. When applied with functional OCT techniques such as OCT angiography, Doppler OCT, and OCT elastography, the disclosed methods provide improved image quality and decreased computational cost compared to other methods of bulk motion compensation. |
| FILED | Tuesday, April 02, 2019 |
| APPL NO | 17/044559 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/102 (20130101) Original (OR) Class A61B 5/0066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944424 | Bier et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Elianna Bier (Durham, North Carolina); Bastiaan Driehuys (Chapel Hill, North Carolina); Ziyi Wang (Durham, North Carolina); Sudarshan Rajagopal (Chapel Hill, North Carolina) |
| ABSTRACT | Methods and systems with 129Xe dynamic spectroscopy with a fitting function that includes one or more non-Lorentzians, optionally with a barrier Voigt, and signal processing for identifying cardiogenic oscillations for evaluating disease states, use in drug discovery or monitoring disease status. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 16/406630 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0813 (20130101) Original (OR) Class A61B 5/7282 (20130101) A61B 2576/02 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/543 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944429 | Datta et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Sandeep Robert Datta (Cambridge, Massachusetts); Alexander B. Wiltschko (Cambridge, Massachusetts); Matthew J. Johnson (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods are disclosed to objectively identify sub-second behavioral modules in the three-dimensional (3D) video data that represents the motion of a subject. Defining behavioral modules based upon structure in the 3D video data itself— rather than using a priori definitions for what should constitute a measurable unit of action— identifies a previously-unexplored sub-second regularity that defines a timescale upon which behavior is organized, yields important information about the components and structure of behavior, offers insight into the nature of behavioral change in the subject, and enables objective discovery of subtle alterations in patterned action. The systems and methods of the invention can be applied to drug or gene therapy classification, drug or gene therapy screening, disease study including early detection of the onset of a disease, toxicology research, side-effect study, learning and memory process study, anxiety study, and analysis in consumer behavior. |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/180677 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/00 (20130101) A61B 5/1123 (20130101) A61B 5/1128 (20130101) Original (OR) Class A61B 5/7267 (20130101) A61B 2503/40 (20130101) A61B 2503/42 (20130101) A61B 2576/00 (20130101) Electric Digital Data Processing G06F 18/295 (20230101) G06F 18/2135 (20230101) Image Data Processing or Generation, in General G06T 7/20 (20130101) Image or Video Recognition or Understanding G06V 10/85 (20220101) G06V 10/147 (20220101) G06V 10/7715 (20220101) G06V 40/20 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944624 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Bingcheng Wang (Solon, Ohio); Bin Su (Cleveland, Ohio); Aaron Petty (Parma, Ohio) |
| ABSTRACT | A method of treating cancer in a subject includes administering to the subject a therapeutically effective amount of a compound, the small molecule having a general formula: A-L-X—Z (I). |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/628990 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Original (OR) Class A61K 45/06 (20130101) Heterocyclic Compounds C07D 403/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944625 | Bradner et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | James Bradner (Weston, Massachusetts); Jun Qi (Sharon, Massachusetts); Dennis Buckley (Cambridge, Massachusetts); Leonard I. Zon (Brookline, Massachusetts); Elizabeth Macari (Wilmington, Massachusetts) |
| ABSTRACT | The present invention relates to methods, compositions and kits for treatment of ribosomal disorders and ribosomopathies, e.g. Diamond Blackfan anemia (DBA). In some embodiments, the invention relates to the use of novel classes of compounds, i.e. inhibitors of RSK (p90S6K); inhibitors of p70S6K; and inhibitors of rps6, to treat ribosomal disorders and ribosomopathies. In some embodiments, the invention relates to the use of specific Chk2 inhibitors and to the use of specific phenothiazine derivatives to treat ribosomal disorders and ribosomopathies, e.g. DBA. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/175079 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/225 (20130101) A61K 31/403 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/5415 (20130101) A61K 31/7048 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944626 | Larsen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Scott D. Larsen (South Lyon, Michigan); Brandt C. Huddle (Ann Arbor, Michigan); Kun Yang (Ann Arbor, Michigan); Ronald Buckanovich (Ann Arbor, Michigan); Thomas Hurley (Indianapolis, Indiana) |
| ABSTRACT | This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a thiopyrimidinone structure which function as inhibitors of ALDH protein, and their use as therapeutics for the treatment of cancer and other diseases. |
| FILED | Tuesday, June 20, 2017 |
| APPL NO | 16/311533 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/522 (20130101) A61K 31/522 (20130101) A61K 31/555 (20130101) A61K 31/555 (20130101) A61K 31/4745 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 31/7068 (20130101) A61K 39/395 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944637 | Singh et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Anirudha Singh (Baltimore, Maryland); Shimon Unterman (Brookline, Massachusetts); Michael Corvelli (Baltimore, Maryland); Jennifer Elisseeff (Baltimore, Maryland) |
| ABSTRACT | The present invention provides novel biomaterial compositions and methods having a technology to improve retention of hyaluronic acid (HA). The biomaterial compositions utilize small HA binding peptides and extracellular matrix binding (ECM) peptides that are tethered to synthetic biocompatible polymers. When tethered to the polymers, the peptide region allows the polymers to bind to HA and to tissues such as cartilage. The novel biomaterial compositions can be used to coat or chemically modify cartilage or tissues with a biologically compatible polymer having HA binding peptides, which allow HA to bind to the surface of the cartilage or tissues. Methods of using same are also provided. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 17/459201 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0048 (20130101) A61K 31/728 (20130101) Original (OR) Class A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 47/60 (20170801) A61K 47/6957 (20170801) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/20 (20130101) A61L 27/227 (20130101) A61L 2400/10 (20130101) A61L 2400/18 (20130101) A61L 2430/06 (20130101) A61L 2430/16 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944648 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seattle, Washington) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seattle, Washington) |
| INVENTOR(S) | Yvonne Y. Chen (Los Angeles, California); Eugenia Zah (Los Angeles, California); Michael C. Jensen (Seattle, Washington) |
| ABSTRACT | A CD19-OR-CD20 chimeric antigen receptor (CAR) protein construct is provided. Also provided are nucleic acids encoding the CD19-OR-CD20 CAR; and methods of use, e.g. in the treatment of B cell malignancies. The CD19-OR-CD20 CAR of the invention is a bispecific CAR that can trigger T-cell activation upon detection of either CD19 or CD20 (or both). It is a single molecule that confers two-input recognition capability upon human T cells engineered to stably express this CAR. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/238210 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70596 (20130101) C07K 16/46 (20130101) C07K 16/2803 (20130101) C07K 16/2887 (20130101) C07K 2317/31 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944665 | Kipnis et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Jonathan Kipnis (Charlottesville, Virginia); Antoine Louveau (Charlottesville, Virginia); Sandro Da Mesquita (Charlottesville, Virginia) |
| ABSTRACT | In some embodiments herein, methods, compositions, and uses for modulating lymphatic vessels of the central nervous system are described. In some embodiments, methods, compositions, or uses for treating, preventing, or ameliorating symptoms of a neurodegenerative disease comprise by increasing flow via meningeal lymphatic vessels are described. In some embodiments, methods, compositions, or uses for treating, preventing, or ameliorating symptoms of inflammatory neurological disease be inhibiting or preventing immune cell migration through meningeal lymphatic vessels are described. |
| FILED | Wednesday, May 31, 2017 |
| APPL NO | 16/306483 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 38/1825 (20130101) A61K 38/1866 (20130101) Original (OR) Class A61K 41/0057 (20130101) A61K 41/0071 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/067 (20210801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/28 (20180101) Peptides C07K 16/22 (20130101) C07K 16/2863 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944671 | Martin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | James F. Martin (Pearland, Texas); John Leach (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure include methods and compositions related to treating or reducing the severity or delaying the onset of one or more cardiac conditions in a mammal. In particular embodiments, the compositions concern Park2 and its use for a cardiac medical condition. In specific cases, effective amounts of Park2 polynucleotide(s) and/or Park2 polypeptide(s) are provided to an individual in need thereof, including for heart failure, for example. The administration may be locally to the heart, for example. |
| FILED | Thursday, September 06, 2018 |
| APPL NO | 16/644435 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 38/53 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/04 (20180101) Peptides C07K 16/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944673 | Palena et al. |
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| FUNDED BY |
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| APPLICANT(S) | GlobeImmune, Inc. (Louisville, Colorado); The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland); GlobeImmune, Inc. (Louisville, Colorado) |
| INVENTOR(S) | Claudia Palena (Potomac, Maryland); Zhimin Guo (Superior, Colorado); David Apelian (Boonton Township, New Jersey); Jeffrey Schlom (Potomac, Maryland) |
| ABSTRACT | Disclosed are yeast-based immunotherapeutic compositions comprising Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury. |
| FILED | Friday, April 19, 2019 |
| APPL NO | 16/389235 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 36/064 (20130101) A61K 38/17 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2039/51 (20130101) A61K 2039/545 (20130101) A61K 2039/6006 (20130101) A61K 2039/55511 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Peptides C07K 14/435 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944681 | Haynes et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina); University of Maryland (College Park, Maryland) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina); University of Maryland (College Park, Maryland) |
| INVENTOR(S) | Barton F. Haynes (Durham, North Carolina); Hua-Xin Liao (Durham, North Carolina); M. Anthony Moody (Durham, North Carolina); LaTonya Williams (Durham, North Carolina); Kevin J. Wiehe (Durham, North Carolina); Gilad Adi Ofek (College Park, Maryland) |
| ABSTRACT | The invention is directed to HIV-1 neutralizing antibodies and methods for their uses. |
| FILED | Thursday, June 24, 2021 |
| APPL NO | 17/357725 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) Original (OR) Class A61K 39/44 (20130101) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 16/1045 (20130101) C07K 2299/00 (20130101) C07K 2317/24 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944716 | Alsberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Eben Alsberg (Cleveland, Ohio); Rui Tang (Solon, Ohio) |
| ABSTRACT | A composition includes a plurality of particulate coated hydrogel microparticles, each of the microparticles including a hydrogel inner core and a particulate shell defined by a plurality of solid nanoparticles, the particulate shell inhibiting aggregation of the microparticles in an aqueous medium and being permeable to allow release of agents from the hydrogel inner core. |
| FILED | Tuesday, December 07, 2021 |
| APPL NO | 17/544544 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/50 (20130101) A61K 9/501 (20130101) A61K 9/5084 (20130101) A61K 47/02 (20130101) A61K 47/42 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) Original (OR) Class A61L 27/36 (20130101) A61L 27/54 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Peptides C07K 14/78 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2389/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 2533/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944722 | Alsberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Eben Alsberg (Cleveland, Ohio); Oju Jeon (Cleveland, Ohio); Tae-Hee Kim (Cleveland, Ohio) |
| ABSTRACT | A composition includes a dual crosslinkable hydrogel that includes a plurality of polymer macromers, which are crosslinked with a first agent and a second agent different than the first agent, wherein the crosslinks formed using the second agent are reversible and repeatable to allow the mechanical properties of the hydrogel to be dynamically adjusted. |
| FILED | Tuesday, September 14, 2021 |
| APPL NO | 17/474985 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/44 (20130101) Original (OR) Class A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/3608 (20130101) A61L 27/3834 (20130101) A61L 2300/236 (20130101) A61L 2300/252 (20130101) A61L 2300/412 (20130101) A61L 2300/414 (20130101) A61L 2400/16 (20130101) A61L 2430/40 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/002 (20130101) Derivatives of Natural Macromolecular Compounds C08H 1/06 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/08 (20130101) C08L 89/06 (20130101) C08L 89/06 (20130101) C08L 89/06 (20130101) C08L 89/06 (20130101) C08L 2205/04 (20130101) C08L 2312/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944725 | Boodagh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Parnaz Boodagh (Boulder, Colorado); Wei Tan (Broomfield, Colorado); Michael Floren (Broomfield, Colorado) |
| ABSTRACT | The present invention relates to a medical implant, and more particularly, to a vascular implant having a dual coating structure for preventing in-stent restenosis and thrombosis. In one embodiment, the invention contemplates a vascular stent with a coating comprising a hydrophobic, degradable core with a coaxial sheath comprising at least one polyethylene-glycol derivative. In one embodiment, the at least one polyethylene-glycol derivative comprises polyethylene-glycol dimethacrylate. |
| FILED | Friday, June 28, 2019 |
| APPL NO | 17/255879 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/507 (20130101) A61L 31/10 (20130101) Original (OR) Class A61L 31/16 (20130101) A61L 2300/42 (20130101) A61L 2300/416 (20130101) A61L 2300/604 (20130101) A61L 2300/606 (20130101) A61L 2400/12 (20130101) A61L 2420/02 (20130101) A61L 2430/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944814 | Lo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yi-Kai Lo (Los Angeles, California); Wentai Liu (Los Angeles, California); Victor R. Edgerton (Los Angeles, California); Chih-Wei Chang (Los Angeles, California) |
| ABSTRACT | A wireless implant and associated system for motor function recovery after spinal cord injury, and more particularly a multi-channel wireless implant with small package size. The wireless implant can further be used in various medical applications, such as retinal prostheses, gastrointestinal implant, vagus nerve stimulation, and cortical neuromodulation. The system also includes a method and its implementation to acquire the impedance model of the electrode-tissue interface of the implant. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 17/459468 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) A61N 1/0551 (20130101) A61N 1/3787 (20130101) A61N 1/36003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944821 | Lujan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | J. Luis Lujan (Mayfield Heights, Ohio); Ashutosh Chaturvedi (Powell, Ohio); Cameron McIntyre (Cleveland, Ohio) |
| ABSTRACT | A computer-implemented method for determining the volume of activation of neural tissue. In one embodiment, the method uses one or more parametric equations that define a volume of activation, wherein the parameters for the one or more parametric equations are given as a function of an input vector that includes stimulation parameters. After receiving input data that includes values for the stimulation parameters and defining the input vector using the input data, the input vector is applied to the function to obtain the parameters for the one or more parametric equations. The parametric equation is solved to obtain a calculated volume of activation. |
| FILED | Tuesday, March 16, 2021 |
| APPL NO | 17/203044 |
| ART UNIT | 2122 — AI & Simulation/Modeling |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) A61N 1/36082 (20130101) A61N 1/36185 (20130101) Original (OR) Class A61N 1/37252 (20130101) Electric Digital Data Processing G06F 18/214 (20230101) G06F 18/2411 (20230101) Computer Systems Based on Specific Computational Models G06N 5/025 (20130101) G06N 7/01 (20230101) G06N 20/00 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/30 (20180101) G16H 20/40 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944848 | Bar-Zion et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Avinoam D. Bar-Zion (Pasadena, California); Atousa Nourmahnad (Pasadena, California); David Maresca (Pasadena, California); Mikhail Shapiro (Pasadena, California) |
| ABSTRACT | The system and process of therapeutic and effective cavitation by using ultrasound to collapse gas vesicles as well as cavitate the bubbles produced from the collapsed gas vesicles. Therapeutic effect includes, but is not limited to lysing cells by cavitation. The cells expressing the gas vesicles can optionally be used as delivery cells to preform tasks such as transporting the gas vesicles into deep tissue areas, releasing compounds at the cavitation site, and more. The gas vesicles can optionally be modified to facilitate getting the bubbles near the cavitation targets by functionalizing the gas vesicles. |
| FILED | Friday, July 29, 2022 |
| APPL NO | 17/816373 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0004 (20130101) A61N 2007/0039 (20130101) A61N 2007/0052 (20130101) A61N 2007/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944850 | Burdette |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Acoustic MedSystems, Inc. (Savoy, Illinois) |
| ASSIGNEE(S) | Acoustic MedSystems, Inc. (Savoy, Illinois) |
| INVENTOR(S) | Everette C. Burdette (Savoy, Illinois) |
| ABSTRACT | A multi-angular ultrasound device. Multi-angular ablation patterns are achieved by a catheter-based ultrasound transducer having a plurality of transducer zones. A multi-chambered balloon is positioned on the catheter. |
| FILED | Monday, October 18, 2021 |
| APPL NO | 17/504301 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/12 (20130101) A61B 8/085 (20130101) A61B 8/445 (20130101) A61B 2018/00023 (20130101) A61B 2018/00517 (20130101) A61B 2018/00523 (20130101) A61B 2018/00791 (20130101) A61B 2090/378 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/022 (20130101) Original (OR) Class A61N 2007/027 (20130101) A61N 2007/0043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944966 | Aksimentiev |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Aleksei Aksimentiev (Urbana, Illinois) |
| ABSTRACT | Aspects of the subject disclosure may include, for example, an apparatus comprising: a membrane, wherein the membrane has a first side and a second side, wherein the membrane has a first pore disposed therein, wherein the first pore extends through the membrane from the first side of the membrane to the second side of the membrane, wherein the membrane has a second pore disposed therein, and wherein the second pore extends through the membrane from the first side of the membrane to the second side of the membrane; a first channel disposed on the first side of the membrane, wherein the first channel is along a first longitudinal axis; a second channel disposed on the first side of the membrane, wherein the second channel is along a second longitudinal axis, and wherein the first channel and the second channel are disposed side by side adjacent to each other; a third channel disposed on the second side of the membrane, wherein the third channel is along a third longitudinal axis, wherein the third channel is in first fluid communication with the first channel via the first pore, and wherein the third channel is in second fluid communication with the second channel via the second pore; and one or more sensors disposed at one or more locations to facilitate sequencing of a molecule that extends from the first channel, through the first pore across at least a portion of the third channel, and through the second pore into the second channel. Additional embodiments are disclosed. |
| FILED | Thursday, October 28, 2021 |
| APPL NO | 17/513516 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Original (OR) Class B01L 2200/0652 (20130101) B01L 2300/0663 (20130101) B01L 2300/0896 (20130101) B01L 2400/0415 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944967 | Ros et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexandra Ros (Phoenix, Arizona); Daihyun Kim (Mesa, Arizona); Jinghui Luo (Covina, California) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Alexandra Ros (Phoenix, Arizona); Daihyun Kim (Mesa, Arizona); Jinghui Luo (Covina, California) |
| ABSTRACT | Sub-micrometer bioparticles are separated by size in a microfluidic channel utilizing a ratchet migration mechanism. A structure within the microfluidic channel includes an array of micro-posts arranged in laterally shifted rows. Reservoirs are disposed at each end of the microfluidic channel. A biased AC potential is applied across the channel via electrodes immersed into fluid in each of the reservoirs to induce a non-uniform electric field through the microfluidic channel. The applied potential comprises a first waveform with a first frequency that induces electro-kinetic flow of sub-micrometer bioparticles in the microfluidic channel, and an intermittent superimposed second waveform with a higher frequency. The second waveform selectively induces a dielectrophoretic trapping force to selectively impart ratchet migration based on particle size for separating the sub-micrometer bioparticles by size in the microfluidic channel. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/524976 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2400/086 (20130101) B01L 2400/0406 (20130101) B01L 2400/0415 (20130101) B01L 2400/0424 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 5/028 (20130101) B03C 2201/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2001/4038 (20130101) G01N 2015/0038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944971 | Kapur et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Ravi Kapur (Sharon, Massachusetts); Kyle C. Smith (Cambridge, Massachusetts); Mehmet Toner (Charlestown, Massachusetts) |
| ABSTRACT | A microfluidic device includes a particle sorting region having a first, second and third microfluidic channels, a first array of islands separating the first microfluidic channel from the second microfluidic channel, and a second array of islands separating the first microfluidic channel from the third microfluidic channel, in which the island arrays and the microfluidic channels are arranged so that a first fluid is extracted from the first microfluidic channel into the second microfluidic channel and a second fluid is extracted from the third microfluidic channel into the first microfluidic channel, and so that particles are transferred from the first fluid sample into the second fluid sample within the first microfluidic channel. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/245770 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502746 (20130101) B01L 3/502753 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 3/502776 (20130101) B01L 2200/12 (20130101) B01L 2200/0631 (20130101) B01L 2200/0647 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2200/0684 (20130101) B01L 2300/185 (20130101) B01L 2300/0681 (20130101) B01L 2300/0877 (20130101) B01L 2400/043 (20130101) B01L 2400/082 (20130101) B01L 2400/0409 (20130101) B01L 2400/0415 (20130101) B01L 2400/0436 (20130101) B01L 2400/0457 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 15/0255 (20130101) G01N 15/0618 (20130101) G01N 15/1484 (20130101) G01N 2001/4088 (20130101) G01N 2015/0053 (20130101) G01N 2015/0065 (20130101) G01N 2015/149 (20130101) G01N 2015/0288 (20130101) G01N 2015/1486 (20130101) G01N 2015/1493 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944972 | Kapur et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Ravi Kapur (Sharon, Massachusetts); Kyle C. Smith (Cambridge, Massachusetts); Mehmet Toner (Charlestown, Massachusetts) |
| ABSTRACT | A microfluidic device includes: a first microfluidic channel; a second microfluidic channel extending along the first microfluidic channel; and a first array of islands separating the first microfluidic channel from the second microfluidic channel, in which each island is separated from an adjacent island in the array by an opening that fluidly couples the first microfluidic channel to the second microfluidic channel, in which the first microfluidic channel, the second microfluidic channel, and the islands are arranged so that a fluidic resistance of the first microfluidic channel increases relative to a fluidic resistance of the second microfluidic channel along a longitudinal direction of the first microfluidic channel such that, during use of the microfluidic device, a portion of a fluid sample flowing through the first microfluidic channel passes through one or more of the openings between adjacent islands into the second microfluidic channel. |
| FILED | Tuesday, June 01, 2021 |
| APPL NO | 17/335510 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502746 (20130101) B01L 3/502753 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 3/502776 (20130101) B01L 2200/12 (20130101) B01L 2200/0631 (20130101) B01L 2200/0647 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2200/0684 (20130101) B01L 2300/185 (20130101) B01L 2300/0681 (20130101) B01L 2300/0877 (20130101) B01L 2400/043 (20130101) B01L 2400/082 (20130101) B01L 2400/0409 (20130101) B01L 2400/0415 (20130101) B01L 2400/0436 (20130101) B01L 2400/0457 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 15/0255 (20130101) G01N 15/0618 (20130101) G01N 15/1484 (20130101) G01N 2001/4088 (20130101) G01N 2015/0053 (20130101) G01N 2015/0065 (20130101) G01N 2015/149 (20130101) G01N 2015/0288 (20130101) G01N 2015/1486 (20130101) G01N 2015/1493 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945107 | Lerner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona) |
| INVENTOR(S) | Zachary Forest Lerner (Flagstaff, Arizona); Greg Orekhov (Flagstaf, Arizona); Jason Luque (Flagstaff, Arizona) |
| ABSTRACT | A method of controlling a drive motor for a powered ankle exoskeleton is disclosed. The method includes modeling motor drive current as a linear function of desired torque and ankle angular velocity, and then controlling motor current as a function of measured torque and determined ankle angular velocity. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/207317 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) A61H 2003/007 (20130101) A61H 2201/123 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/1215 (20130101) A61H 2201/5061 (20130101) A61H 2201/5071 (20130101) A61H 2201/5097 (20130101) A61H 2205/106 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) Original (OR) Class B25J 9/163 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945781 | Suto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Southern Research Institute (Birmingham, Alabama); UAB Research Foundation (Birmingham, Alabama); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Southern Research Institute (Birmingham, Alabama); UAB Research Foundation (Birmingham, Alabama); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Mark J. Suto (Homewood, Alabama); Bini Mathew (Hoover, Alabama); Anupam Agarwal (Mountain Brook, Alabama); Amie M. Traylor (Talladega, Alabama) |
| ABSTRACT | The present disclosure is concerned with thioquinolinone compounds for the treatment of disorders associated with heme oxygenase-1 (HO-1) signaling dysfunction such as, for example, kidney diseases (e.g., chronic kidney disease, acute kidney injury). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/183281 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 321/28 (20130101) Heterocyclic Compounds C07D 213/70 (20130101) C07D 215/36 (20130101) Original (OR) Class C07D 215/40 (20130101) C07D 215/48 (20130101) C07D 217/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945803 | Lennek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tosk, Inc. (Mountain View, California) |
| ASSIGNEE(S) | Tosk, Inc. (Mountain View, California) |
| INVENTOR(S) | Annie L. Lennek (Mountain View, California); Stephen D. Yanofsky (Mountain View, California); Brian D. Frenzel (Mountain View, California); Solomon B. Ungashe (Mountain View, California); William A. Garland (Mountain View, California); Philip Liaw (Mountain View, California) |
| ABSTRACT | RAS modulating compounds and methods of using the same are provided. The compounds find use in modulating the activity of a target RAS in a sample. The target RAS can be a mutant RAS that is implicated in a disease of interest. In some cases, the subject compounds can inhibit the growth of cancer cells whose progression is driven by kRAS or a mutated kRAS. Methods of treating a subject for a RAS driven disease including administering a therapeutically effective amount of the subject compound are provided. Also provided are pharmaceutical compositions and kits which include the subject compounds. |
| FILED | Tuesday, August 06, 2019 |
| APPL NO | 17/260711 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 403/14 (20130101) Original (OR) Class C07D 413/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945816 | Hatcher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | John M. Hatcher (Boston, Massachusetts); Nathanael S. Gray (Boton, Massachusetts); Jaebong Jang (Brookline, Massachusetts); Dries De Clercq (Boston, Massachusetts); Pasi Janne (Needham, Massachusetts); Jamie A. Saxon (Boston, Massachusetts); Michael Eck (Boston, Massachusetts); David A. Scott (Boston, Massachusetts); Alyssa Verano (Boston, Massachusetts) |
| ABSTRACT | The application relates to a compound having Formula X: which modulates the activity of HER2 and/or a mutant thereof, and/or EGFR and/or a mutant thereof, a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease in which HER2 and/or a mutant thereof, and/or EGFR and/or a mutant thereof, plays a role. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/451538 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945827 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Rapafusyn Pharmaceuticals, Inc. (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Jun Liu (Clarksville, Maryland); Sam Hong (Baltimore, Maryland); Brett R. Ullman (Baltimore, Maryland); Joseph E. Semple (Baltimore, Maryland); Kana Yamamoto (Baltimore, Maryland); Puneet Kumar (Baltimore, Maryland); Magesh Sadagopan (Baltimore, Maryland); Jennifer C. Schmitt (Baltimore, Maryland) |
| ABSTRACT | The present disclosure provides macrocyclic compounds inspired by the immunophilin ligand family of natural products FK506 and rapamycin. The generation of a Rapafucin library of macrocyles that contain FK506 and rapamycin binding domains should have great potential as new leads for developing drugs to be used for treating diseases. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/332331 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 498/04 (20130101) C07D 498/14 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/3258 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945841 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Gerogia State University Research Foundation, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Baozhong Wang (Duluth, Georgia); Lei Deng (Atlanta, Georgia) |
| ABSTRACT | Disclosed are universal influenza based on a truncated influenza hemagglutin (HA) protein lacking a head domain (hrHA). Also disclosed is a composition comprising a nanoparticle coated with a disclosed hrHA polypeptide. Also disclosed is a composition comprising a virus like particle (VLP) expressing on its surface a disclosed hrHA polypeptide. |
| FILED | Thursday, October 04, 2018 |
| APPL NO | 16/649905 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 39/145 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16122 (20130101) C12N 2760/16123 (20130101) C12N 2760/16134 (20130101) C12N 2760/16222 (20130101) C12N 2760/16223 (20130101) C12N 2760/16234 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945845 | Waldman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Ben Waldman (Cambridge, Massachusetts); Sebastian Lourido (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides genetically altered protozoan parasites comprising a mutation in a bradyzoite formation deficient 1 (BFD1) gene, wherein the mutation inhibits differentiation of the parasite into a bradyzoite. The genetically altered protozoan parasites can be utilized in vaccine compositions and in methods of treating apicomplexan parasite infection. |
| FILED | Saturday, May 30, 2020 |
| APPL NO | 17/595894 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/002 (20130101) A61K 2039/52 (20130101) A61K 2039/523 (20130101) A61K 2039/585 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/02 (20180101) A61P 37/04 (20180101) Peptides C07K 14/45 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/10 (20130101) C12N 15/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945853 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Qiuhong Li (Gainesville, Florida); Mohan Raizada (Alachua, Florida) |
| ABSTRACT | Provided herein are polynucleic acids and expression vectors for the expression and secretion of angiotensin peptide fragments (e.g., angiotensin-(1-7)) in probiotic bacteria. Provided herein are also probiotic compositions that enable efficient, cost-effective and patient friendly oral therapeutics for treating diverse pathological conditions that involve the renin-angiotensin system (RAS), e.g., pulmonary hypertension, diabetes, diabetic complications, cardiovascular diseases, and ocular inflammatory and neurodegenerative diseases. |
| FILED | Tuesday, June 14, 2022 |
| APPL NO | 17/839815 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 35/741 (20130101) A61K 35/747 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 2035/115 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/00 (20180101) A61P 3/10 (20180101) A61P 9/12 (20180101) A61P 27/02 (20180101) A61P 29/00 (20180101) Peptides C07K 7/14 (20130101) C07K 14/28 (20130101) C07K 14/47 (20130101) C07K 14/195 (20130101) C07K 14/575 (20130101) Original (OR) Class C07K 19/00 (20130101) C07K 2319/02 (20130101) C07K 2319/50 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/00 (20130101) C12N 9/485 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11945855 — Recombinant polypeptides comprising modified MHC class II DRa1 domains and methods of use
| US 11945855 | Meza-Romero et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Roberto Meza-Romero (Beaverton, Oregon); Arthur A. Vandenbark (Portland, Oregon); Halina Offner (Portland, Oregon) |
| ABSTRACT | Recombinant polypeptides comprising a modified DRα1 domain are provided. In some embodiments, the polypeptides include the modified DRα1 domain, an antigenic peptide, and optionally a linker sequence. Pharmaceutical compositions comprising the recombinant polypeptides, methods of treating inflammatory disease using said recombinant polypeptides or pharmaceutical compositions, and expression constructs comprising nucleic acids that encode the recombinant polypeptides are also provided. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/282455 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) A61K 2039/6031 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Peptides C07K 14/70539 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945892 | Appel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior Univeristy (Stanford, California) |
| INVENTOR(S) | Eric A. Appel (Palo Alto, California); Caitlin Maikawa (Boston, Massachusetts); Joseph L. Mann (Mountain View, California) |
| ABSTRACT | A polyacrylamide-based copolymer reduces or prevents aggregation of biologic molecules including proteins, peptides, and nucleic acids, and lipid-based vehicles such as liposomes, lipid nanoparticles, polymerosomes, and micelles, in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of the molecules in the formulation. Methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used for treating conditions including diabetes. |
| FILED | Friday, October 07, 2022 |
| APPL NO | 17/962252 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) A61K 9/5146 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946028 | Huh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Dongeun Huh (Villanova, Pennsylvania); Mark Mondrinos (Philadelphia, Pennsylvania) |
| ABSTRACT | The presently disclosed subject matter provides a biomimetic organ model, and methods of its production and use. In one exemplary embodiment, the biomimetic organ model can be a multi-layer model including a at least two microchannels and at least one chamber slab with at least one membrane coated with cells disposed between at least one microchannel and the at least one chamber slab. In another exemplary embodiment, the biomimetic organ disease model can be a five-layer model including a first and second microchannel with a membrane-gel layer-membrane coated or encompassing cells disposed between the microchannels. In certain embodiments, at least one device can be coupled to the biomimetic organ model that delivers an agent to at least one microchannel. |
| FILED | Tuesday, July 26, 2022 |
| APPL NO | 17/814948 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/22 (20130101) A61L 27/50 (20130101) A61L 27/52 (20130101) A61L 27/3633 (20130101) A61L 27/3804 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) C08L 83/04 (20130101) Apparatus for Enzymology or Microbiology; C12M 3/00 (20130101) C12M 21/08 (20130101) Original (OR) Class C12M 23/00 (20130101) C12M 23/20 (20130101) C12M 25/02 (20130101) C12M 25/14 (20130101) C12M 29/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0062 (20130101) C12N 5/0068 (20130101) C12N 2533/30 (20130101) C12N 2533/54 (20130101) C12N 2535/00 (20130101) C12N 2537/10 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) G01N 33/5044 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 23/30 (20130101) G09B 23/306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946030 | Laurencin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Cato T. Laurencin (Farmington, Connecticut); Lakshimi S. Nair (Farmington, Connecticut); Mohammed Barajaa (Farmington, Connecticut) |
| ABSTRACT | System and methods for the culturing of multiple independent cell types under uniform conditions. |
| FILED | Thursday, December 17, 2020 |
| APPL NO | 17/124728 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 23/34 (20130101) Original (OR) Class C12M 37/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946035 | Ludlam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cairn Biosciences, Inc. (San Francisco, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of The University of California (Oakland, California); Cairn Biosicences, Inc. (San Francisco, California) |
| INVENTOR(S) | Mary J. C. Ludlam (San Francisco, California); Austin Blanco (Lincoln, California); David Wartmann (Berkeley, California); Richard A. Mathies (Walnut Creek, California) |
| ABSTRACT | Devices, systems, methods, and techniques regarding a microfluidic-enabled multiwell device with closed-loop monitoring and control of various parameters of the microfluidic environment are provided. A microfluidic-enabled multiwell device may have a removable and disposable microfluidics module layer and a reusable sensor module layer. The sensor module layer may be configured to monitor and control parameters of the environment inside the microfluidics module layer, store data regarding the parameters, and wirelessly transmit the data. The device may be configured to individually address flow of fluid to any one of a plurality of wells, using one or more pneumatic micropumps. The device may be configured to automatically execute one or more live cell cultures, assays, and/or protocols. The device may be configured to be received in a docking station and/or portable manifold adapter, and to be fluidly, pneumatically, and/or electronically coupled to the station, adapter, or other laboratory equipment. |
| FILED | Tuesday, May 15, 2018 |
| APPL NO | 16/614290 |
| ART UNIT | 1799 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 23/16 (20130101) C12M 29/00 (20130101) C12M 29/20 (20130101) C12M 41/44 (20130101) C12M 41/48 (20130101) Original (OR) Class Electric Digital Data Processing G06F 3/0481 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946040 | Joung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Julian Grunewald (Charlestown, Massachusetts); Ronghao Zhou (Charlestown, Massachusetts) |
| ABSTRACT | Engineered adenine base editor (ABE) variants with reduced RNA editing activity, and methods of using the same. |
| FILED | Tuesday, February 04, 2020 |
| APPL NO | 16/781979 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1024 (20130101) Original (OR) Class Enzymes C12Y 305/04004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946046 | Pulst et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Stefan M. Pulst (Sandy, Utah); Daniel R. Scoles (Salt Lake City, Utah); Sharan Paul (Salt Lake City, Utah) |
| ABSTRACT | Methods of minimizing dysregulation of Staufen1-associated RNA metabolism can include introducing an amount of a Staufen1-regulating agent to a target cell sufficient to minimize the dysregulation. Therapeutic compositions for treating a neurodegenerative condition associated with Staufen1-induced dysregulation of RNA metabolism can include a therapeutically effective amount of a Staufen1-regulating agent and a pharmaceutically acceptable carrier. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 15/734174 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/12 (20130101) C12N 2310/141 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946047 | Zeng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | Texas Tech University System (Lubbock, Texas) |
| INVENTOR(S) | Mingtao Zeng (El Paso, Texas); Lihong Wu (El Paso, Texas) |
| ABSTRACT | The present invention includes a composition and method for decreasing Bacillus anthracis virulence or toxicity comprising: at least one inhibitor that decreases an expression of one or more host genes selected from G6pc, Rgs1, Fosl2, Hcar2, Cxcl2 and Cxcl3, or Serpine1 (PAI-1). |
| FILED | Wednesday, October 23, 2019 |
| APPL NO | 16/660986 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946049 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aiming Yu (Granite Bay, California); Pui Yan Ho (Davis, California); Meijuan Tu (Davis, California); Joseph L. Jilek (Davis, California); Qianyu Zhang (Davis, California); Hannah E. Petrek (Davis, California) |
| ABSTRACT | Provided are hybrid tRNA/pre-miRNA molecules, e.g., comprising a single tRNA and one, two or more pre-miRNA molecules, useful for the production and therapeutic delivery of an inserted RNA sequence, e.g., one or more miRNAs. Also provided are liposomes and nanoparticles that include the hybrid tRNA/pre-miRNA molecules. Methods of treating cancer by administration of the hybrid tRNA/pre-miRNA molecules are also provided. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 17/056203 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/6911 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2310/531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946053 | Paugh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee) |
| INVENTOR(S) | Steven W. Paugh (Memphis, Tennessee); William E. Evans (Memphis, Tennessee); Erik Bonten (Arlington, Tennessee) |
| ABSTRACT | The invention provides methods for overcoming glucocorticoid resistance of cancers by inhibition of CASP1. Also disclosed are diagnostic methods for determining glucocorticoid resistance potential by measuring expression level or promoter methylation status of CASP1 gene and/or NLRP3 gene. |
| FILED | Wednesday, October 02, 2019 |
| APPL NO | 16/590588 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/197 (20130101) A61K 31/197 (20130101) A61K 31/198 (20130101) A61K 31/198 (20130101) A61K 31/401 (20130101) A61K 31/401 (20130101) A61K 31/551 (20130101) A61K 31/551 (20130101) A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 31/713 (20130101) A61K 31/4025 (20130101) A61K 31/4025 (20130101) A61K 38/06 (20130101) A61K 38/07 (20130101) A61K 38/57 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 5/44 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2310/531 (20130101) C12N 2320/31 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946055 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Chang C. Liu (Irvine, California); Alon Wellner (Irvine, California); Ziwei Zhong (Irvine, California); Arjun Ravikumar (Irvine, California); Andrew Kruse (Boston, Massachusetts); Conor Thomas McMahon (Brighton, Massachusetts) |
| ABSTRACT | Disclosed herein are methods, compositions, and kits for engineering proteins using error-prone orthogonal replication (epOrthoRep) and yeast surface display (YSD). |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 17/546515 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 2317/569 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1252 (20130101) C12N 15/70 (20130101) Original (OR) Class C12N 15/81 (20130101) C12N 15/102 (20130101) C12N 15/1058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946064 | Peruzzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Pierpaolo Peruzzi (Newton, Massachusetts); Ennio Antonio Chiocca (Boston, Massachusetts) |
| ABSTRACT | Described herein are compositions and methods for treating a disease in a subject by administering delivery vectors that express artificial microRNAs, artificial microRNA clusters, and/or a combination of microRNA clusters and associated non-coding RNAs to the subject. Also described herein are methods for preparing artificial microRNAs and artificial microRNA clusters. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 17/051527 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/16 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) C12N 2320/30 (20130101) C12N 2330/50 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946066 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Xiaojing Gao (Pasadena, California); Lucy S. Chong (Pasadena, California); Michael B. Elowitz (Pasadena, California); Matthew S-M Kim (San Francisco, California) |
| ABSTRACT | Disclosed herein include methods, compositions, and systems suitable for use in delivering a polynucleotide to a target cell of a subject in need thereof. In some embodiments, a viral vector comprises a polynucleotide encoding nucleoprotein (N), phosphoprotein (P), matrix protein (M), RNA-dependent RNA polymerase (L), and one or more transgenes. The viral vector can comprise one or more of a conditionally stable fusion protein, a protease fusion protein, a degron fusion protein, and/or a glycoprotein derived of another species than the viral vector polynucleotide to enable control of viral vector transduction and/or replication. |
| FILED | Friday, September 23, 2022 |
| APPL NO | 17/935024 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 16/18 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2319/30 (20130101) C07K 2319/50 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/506 (20130101) C12N 15/62 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2740/11045 (20130101) C12N 2760/20143 (20130101) C12N 2810/6054 (20130101) C12N 2820/002 (20130101) C12N 2820/007 (20130101) Enzymes C12Y 304/21098 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946075 | Pokorski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Jonathan Pokorski (San Diego, California); Nicole Steinmetz (San Diego, California); Parker Lee (Los Angeles, California) |
| ABSTRACT | A method of producing plant virus-like particles includes freeze drying an aqueous solution of plant virus particles to produce a substantially RNA-free plant virus-like particles. |
| FILED | Tuesday, July 19, 2022 |
| APPL NO | 17/868144 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2770/18023 (20130101) C12N 2770/18051 (20130101) C12N 2770/32023 (20130101) C12N 2770/32051 (20130101) Enzymes C12Y 301/27005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946082 | Rosbash et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brandeis University (Waltham, Massachusetts) |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts) |
| INVENTOR(S) | Michael Rosbash (Waltham, Massachusetts); Aoife McMahon (Waltham, Massachusetts); Weijin Xu (Waltham, Massachusetts); Hua Jin (Waltham, Massachusetts) |
| ABSTRACT | The present invention features fusion polypeptides comprising an RNA binding polypeptide operationally linked to an RNA modifying enzyme (e.g., adenosine deaminase, cytidine deaminase), and methods of use therefore. |
| FILED | Friday, May 13, 2022 |
| APPL NO | 17/743859 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/47 (20130101) C07K 2319/20 (20130101) C07K 2319/85 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/78 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 2750/14122 (20130101) Enzymes C12Y 305/04004 (20130101) C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946094 | She et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Augusta University Research Institute, Inc. (Augusta, Georgia) |
| ASSIGNEE(S) | Augusta University Research Institute, Inc. (Augusta, Georgia) |
| INVENTOR(S) | Jin-Xiong She (Augusta, Georgia); Robert Schleifer (Sugar Hill, Georgia); Shuchun Li (Martinez, Georgia) |
| ABSTRACT | A method for identifying drug resistant genes and compositions containing agents that downregulate these genes in combination with a cancer therapeutic. |
| FILED | Monday, December 10, 2018 |
| APPL NO | 16/214658 |
| ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 33/57496 (20130101) G01N 2500/02 (20130101) G01N 2500/10 (20130101) G01N 2800/44 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946105 | Meyerson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Matthew Meyerson (Concord, Massachusetts); Aleksandar Kostic (Brookline, Massachusetts) |
| ABSTRACT | Methods for predicting risk of developing colorectal cancer, for treating colorectal cancer, and reducing risk of developing colorectal cancer. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 17/345311 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6886 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946164 | Xie |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| ASSIGNEE(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| INVENTOR(S) | Jingwei Xie (Omaha, Nebraska) |
| ABSTRACT | Expanded, nanofiber structures are provided as well as methods of use thereof and methods of making. |
| FILED | Tuesday, July 19, 2022 |
| APPL NO | 17/868519 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 2791/005 (20130101) B29C 2791/006 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2073/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) D01D 5/0007 (20130101) Original (OR) Class D01D 5/0015 (20130101) D01D 5/0023 (20130101) D01D 5/0038 (20130101) D01D 5/0046 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/625 (20130101) D01F 8/14 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 3/011 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 23/10 (20130101) D06M 2101/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946846 | Demirci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Utkan Demirci (Cambridge, Massachusetts); Waseem Asghar (Boston, Massachusetts) |
| ABSTRACT | A system and method for sorting sperm is provided. The system includes a housing and a microfluidic system supported by the housing. The system also includes an inlet providing access to the microfluidic system to deliver sperm to the microfluidic system and an outlet providing access to the microfluidic system to harvest sorted sperm from the microfluidic system. The microfluidic system provides a flow path for sperm from the inlet to the outlet and includes at least one channel extending from the inlet to the outlet to allow sperm delivered to the microfluidic system through the inlet to progress along the flow path toward the outlet. The microfluidic system also includes a filter including a first plurality of micropores arranged in the flow path between the inlet and the outlet to cause sperm traveling along the flow path to move against through the filter and gravity to reach the outlet. |
| FILED | Wednesday, September 13, 2023 |
| APPL NO | 18/367772 |
| ART UNIT | 1799 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/061 (20130101) C12N 5/0612 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4005 (20130101) G01N 15/00 (20130101) G01N 15/10 (20130101) Original (OR) Class G01N 2001/4088 (20130101) G01N 2015/0003 (20130101) G01N 2015/0065 (20130101) G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) G01N 2800/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946867 | Pertsinidis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Alexandros Pertsinidis (New York, New York); Guanshi Wang (New York, New York) |
| ABSTRACT | Described herein are 3D single-molecule super-resolution imaging systems and methods. The provided systems and methods use modulation interferometry and phase-sensitive detection techniques that achieve less than 2 nanometer axial localization precision, which is well below the 5-10-nanometer-sized individual protein components. To illustrate the capability of this technique in probing the dynamics of complex macromolecular machines, (1) movement of individual multi-subunit E. coli RNA Polymerases were visualized through the complete transcription cycle, (2) kinetics of the initiation-elongation transition were dissected, (3) the conformational changes from the open initiation complex to the elongation complex were analyzed, and (4) the fate of σ70 initiation factors during promoter escape were determined. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 16/608678 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6402 (20130101) G01N 21/6428 (20130101) G01N 21/6456 (20130101) Original (OR) Class G01N 2021/6439 (20130101) G01N 2201/0636 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946925 | Xie |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Ping Xie (Needham, Massachusetts) |
| ABSTRACT | In a nanopore sensor, a nanopore disposed in a support structure has a nanopore diameter and nanopore resistance, RPore. A fluidic passage, disposed in fluidic connection between a first fluidic reservoir and the nanopore, has a cross-sectional extent, along at least a portion of the fluidic passage length, that is greater than the diameter of the nanopore and that is less than the fluidic passage length. The fluidic passage has a fluidic passage resistance, RFP, of at least about 10% of the nanopore resistance, RPore, and no more than about 10 times the nanopore resistance, RPore. The nanopore is disposed in fluidic connection between the fluidic passage and a second fluidic reservoir. At least one electrical transduction element is disposed at the fluidic passage and electrically connected to produce an indication of electrical potential local to the fluidic passage. |
| FILED | Tuesday, April 12, 2022 |
| APPL NO | 17/718619 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 2300/12 (20130101) B01L 2300/0645 (20130101) B01L 2300/0867 (20130101) B01L 2300/0896 (20130101) B01L 2400/0421 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 27/4146 (20130101) G01N 27/4163 (20130101) G01N 27/4473 (20130101) G01N 27/44726 (20130101) G01N 27/44791 (20130101) G01N 33/48721 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946928 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (, None); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (, None) |
| INVENTOR(S) | Ke Xu (Cambridge, Massachusetts); Marc E. Lenburg (Brookline, Massachusetts); Ehab Billatos (Milton, Massachusetts); Alejandro A. Diaz (Boston, Massachusetts) |
| ABSTRACT | Described herein are methods relating to the diagnosis, prognosis, and treatment of airway dysfunction, e.g., bronchiectasis by detecting gene expression in a sample obtained from a subject. Exemplary samples include a bronchial brushing, nasal brushing, sputum, or peripheral blood sample. |
| FILED | Thursday, May 19, 2022 |
| APPL NO | 17/748404 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2539/10 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) Original (OR) Class G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946931 | Ban et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Deependra Kumar Ban (San Diego, California); Ratnesh Lal (La Jolla, California); Gennadi Glinskii (La Jolla, California); Prabhakar R. Bandaru (San Diego, California); Sunil Srivastava (La Jolla, California); Scott John (Los Angeles, California); Tyler Bodily (La Jolla, California); Abhijith Karkisaval Ganapati (La Jolla, California) |
| ABSTRACT | Methods, systems and devices for detecting the presence of a pathogen, for example, a virus (e.g., SARS-CoV-2), or its molecular components, in health care-related samples and/or environmental samples are disclosed. An example system for improving detection of a pathogen includes biosensor device comprising a detection chip and at least one probe that specifically recognizes a pathogen, where the detection chip comprises a graphene field-effect transistor (FET) chip and the probe, which comprises an aptamer, specifically binds to a DNA, RNA, or protein associated with the pathogen. |
| FILED | Monday, January 31, 2022 |
| APPL NO | 17/649554 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6816 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/00 (20130101) G01N 33/5438 (20130101) Original (OR) Class G01N 33/56983 (20130101) G01N 2333/165 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2924/1306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11948300 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SPECTRAL MD, INC. (Dallas, Texas) |
| ASSIGNEE(S) | Spectral MD, Inc. (Dallas, Texas) |
| INVENTOR(S) | Wensheng Fan (Plano, Texas); John Michael DiMaio (Dallas, Texas); Jeffrey E. Thatcher (Irving, Texas); Peiran Quan (Dallas, Texas); Faliu Yi (Allen, Texas); Kevin Plant (Dallas, Texas); Ronald Baxter (Grand Prairie, Texas); Brian McCall (Dallas, Texas); Zhicun Gao (Plano, Texas); Jason Dwight (Dallas, Texas) |
| ABSTRACT | Machine learning systems and methods are disclosed for prediction of wound healing, such as for diabetic foot ulcers or other wounds, and for assessment implementations such as segmentation of images into wound regions and non-wound regions. Systems for assessing or predicting wound healing can include a light detection element configured to collect light of at least a first wavelength reflected from a tissue region including a wound, and one or more processors configured to generate an image based on a signal from the light detection element having pixels depicting the tissue region, determine reflectance intensity values for at least a subset of the pixels, determine one or more quantitative features of the subset of the plurality of pixels based on the reflectance intensity values, and generate a predicted or assessed healing parameter associated with the wound over a predetermined time interval. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/177493 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0077 (20130101) A61B 5/445 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/30088 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11948311 | Cauley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Stephen Cauley (Somerville, Massachusetts); Melissa Haskell (Cambridge, Massachusetts); Lawrence Wald (Cambridge, Massachusetts) |
| ABSTRACT | A combined physics-based and machine learning framework is used for reconstructing images from k-space data, in which motion artifacts are significantly reduced in the reconstructed images. In general, model-based retrospective motion correction techniques are accelerated using fast machine learning (“ML”) steps, which may be implemented using a trained neural network such as a convolutional neural network. In this way, the confidence of a classical physics-based reconstruction is obtained with the computational benefits of an ML-based network. |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 17/442962 |
| ART UNIT | 2672 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/4046 (20130101) G06T 7/251 (20170101) Original (OR) Class G06T 2207/10088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11948389 | Ghimire et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kanchan Ghimire (Arlington, Virginia); Quan Chen (Lexington, Kentucky); Xue Feng (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kanchan Ghimire (Arlington, Virginia); Quan Chen (Lexington, Kentucky); Xue Feng (Lexington, Kentucky) |
| ABSTRACT | The present disclosure relates to a method and apparatus for automatic detection of anatomical sites from tomographic images. The method includes: receiving 3D images obtained by a CT or an MRI system, transforming the images to the DICOM standard patient-based coordinate system, pre-processing the images to have normalized intensity values based on their modality, performing body segmentation, cropping the images to remove excess areas outside the body, and detecting different anatomical sites including head and neck, thorax, abdomen, male pelvis and female pelvis, wherein the step of detecting different anatomical sites comprises: performing slice-level analyses on 2D axial slices to detect the head and neck region using dimensional measurement thresholds based on human anatomy, calculating lung ratios on axial slices to find if lungs are present, determining whether 3D images with lungs present span over the thoracic region, abdomen region, or both, conducting 2D connectivity analyses on axial slices to detect the pelvis region if two separate leg regions are found and differentiating detected pelvis regions as either male pelvis or female pelvis regions based on human anatomy. |
| FILED | Friday, March 11, 2022 |
| APPL NO | 17/693272 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/28 (20220101) G06V 10/34 (20220101) G06V 10/267 (20220101) G06V 10/273 (20220101) G06V 10/457 (20220101) G06V 40/10 (20220101) Original (OR) Class G06V 2201/031 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11944411 | Charalambides et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lifeware Labs, LLC (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Lifeware Labs, LLC (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Alexandros Charalambides (Pittsburgh, Pennsylvania); Brian Stancil (Pittsburgh, Pennsylvania) |
| ABSTRACT | A wearable electronic device comprises a base for mounting a plurality of sensors, where the sensors acquiring physiological data of a user wearing the device. By providing multiple sensors on a single device, additional physiological data, such as pulse transit time, can be provided. To ensure quality data is collected, the device includes a spring mechanism for applying a compressive force on the sensor to force it into the skin of a user. |
| FILED | Wednesday, November 27, 2019 |
| APPL NO | 16/698574 |
| ART UNIT | 3796 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/28 (20210101) A61B 5/0245 (20130101) A61B 5/274 (20210101) A61B 5/352 (20210101) A61B 5/02125 (20130101) Original (OR) Class A61B 5/6823 (20130101) A61B 5/14552 (20130101) A61B 2560/0412 (20130101) A61B 2562/06 (20130101) A61B 2562/146 (20130101) A61B 2562/166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944451 | Mulligan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Flashback Technologies, Inc. (Boulder, Colorado); The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Isobel Jane Mulligan (Niwot, Colorado); Gregory Zlatko Grudic (Niwot, Colorado); Steven L. Moulton (Littleton, Colorado) |
| ABSTRACT | Novel tools and techniques for assessing, predicting and/or estimating effectiveness of fluid resuscitation of a patient and/or an amount of fluid needed for effective resuscitation of the patient, in some cases, noninvasively. |
| FILED | Tuesday, July 26, 2022 |
| APPL NO | 17/873691 |
| ART UNIT | 2459 — Computer Networks |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4836 (20130101) Original (OR) Class Electric Digital Data Processing G06F 16/289 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/01 (20220501) H04L 67/10 (20130101) H04L 67/1008 (20130101) H04L 67/5683 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944493 | Hatlan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sonivate Medical, Inc. (Portland, Oregon) |
| ASSIGNEE(S) | Sonivate Medical, Inc. (Portland, Oregon) |
| INVENTOR(S) | James T. Hatlan (Portland, Oregon); Austen Angell (Portland, Oregon); William McDonough (Portland, Oregon) |
| ABSTRACT | Disclosed are wearable ultrasound probes for use in trauma triage and assessment. The probes define a finger-receiving aperture and include an ultrasound array disposed adjacent the distal end wherein the ultrasound array is angled toward the bottom side of the probe about 10-50 degrees from the longitudinal axis and a second ultrasound array adjacent the distal end and proximal to the first ultrasound array, wherein the second ultrasound array is angled about 105-155 degrees from the first ultrasound array. |
| FILED | Thursday, December 17, 2020 |
| APPL NO | 17/125662 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/4427 (20130101) A61B 8/4455 (20130101) Original (OR) Class A61B 8/4477 (20130101) A61B 8/4488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944624 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Bingcheng Wang (Solon, Ohio); Bin Su (Cleveland, Ohio); Aaron Petty (Parma, Ohio) |
| ABSTRACT | A method of treating cancer in a subject includes administering to the subject a therapeutically effective amount of a compound, the small molecule having a general formula: A-L-X—Z (I). |
| FILED | Tuesday, July 03, 2018 |
| APPL NO | 16/628990 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Original (OR) Class A61K 45/06 (20130101) Heterocyclic Compounds C07D 403/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944964 | Meacham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Mark Meacham (St. Louis, Missouri); Arpita Bose (St. Louis, Missouri); Michael M. Binkley (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | John Mark Meacham (St. Louis, Missouri); Arpita Bose (St. Louis, Missouri); Michael M. Binkley (St. Louis, Missouri) |
| ABSTRACT | A micro-bioelectrochemical cell (μ-BEC) device is disclosed that includes from 4 to 96 microfluidically connected of chambers, in which each chamber encloses a volume of about 1 μL to 2 μL. A working electrode, reference electrode, and counting electrode contacts each volume. The μ-BEC device includes a support layer coated with a working electrode layer, a microfluidics layer containing a plurality of wells, and an electrical layer containing the reference and counter electrodes. Methods of using the μ-BEC device to perform bioelectrochemical measurements of cells are also disclosed. |
| FILED | Wednesday, January 29, 2020 |
| APPL NO | 16/776496 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Original (OR) Class B01L 2300/12 (20130101) B01L 2300/0645 (20130101) B01L 2300/0861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945585 | Zook et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Trevor A. Zook (Stratford, Connecticut); Jason Quevedo (Stratford, Connecticut); Ken Chu (Stratford, Connecticut); David Tam (Seymour, Connecticut) |
| ABSTRACT | An aircraft includes a main body having an empennage, a main rotor assembly mounted on the main body, and a movable control surface assembly supported on the empennage. The movable control surface assembly includes a tube extending from the empennage along a tube axis to a free end, the tube being supported for rotation about the tube axis with respect to the empennage, and a movable control surface mounted on the tube for rotation therewith. The movable control surface is supported on the tube by a connection element that couples the movable control surface to the free end of the tube to rotatably fix the movable control surface with respect to the tube. |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/672376 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 9/02 (20130101) Original (OR) Class B64C 29/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945756 | Sambasivan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Applied Thin Films, Inc. (Skokie, Illinois) |
| ASSIGNEE(S) | APPLIED THIN FILMS, INC. (Skokie, Illinois) |
| INVENTOR(S) | Sankar Sambasivan (Chicago, Illinois); Vikram S. Kaul (Atlanta, Georgia); Francis R. Chapman (Chicago, Illinois) |
| ABSTRACT | A material contains open pores in which the channels and pores that are internally coated with at least one layer of phosphorus-containing alumina. Such material is formed by infiltrating a porous material one or more times with a non-colloidal, low-viscosity liquid coating precursor, drying, and curing the coating precursor to form a phosphorus-containing alumina layer within pores of the material. |
| FILED | Monday, October 19, 2020 |
| APPL NO | 17/073486 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/14 (20130101) C04B 35/83 (20130101) C04B 35/195 (20130101) C04B 35/522 (20130101) C04B 35/522 (20130101) C04B 35/522 (20130101) C04B 35/584 (20130101) C04B 38/00 (20130101) C04B 38/00 (20130101) C04B 38/00 (20130101) C04B 38/00 (20130101) C04B 38/0054 (20130101) C04B 38/0096 (20130101) Original (OR) Class C04B 38/0096 (20130101) C04B 41/009 (20130101) C04B 41/009 (20130101) C04B 41/009 (20130101) C04B 41/009 (20130101) C04B 41/009 (20130101) C04B 41/85 (20130101) C04B 41/4515 (20130101) C04B 41/5092 (20130101) C04B 41/5092 (20130101) C04B 2235/3206 (20130101) C04B 2235/3208 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/125 (20130101) C23C 18/1216 (20130101) C23C 18/1229 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/288 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2300/514 (20130101) F05D 2300/6033 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/60 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/268 (20150115) Y10T 428/24997 (20150401) Y10T 428/249921 (20150401) Y10T 428/249967 (20150401) Y10T 428/249969 (20150401) Y10T 428/249978 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945780 | Gorodetsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alon Gorodetsky (Irvine, California); David Joshua Dibble (Santa Ana, California); Mehran Umerani (Irvine, California); Amir Mazaheripour (Irvine, California); Young Suk Park (Huntington Beach, California); Anthony Burke (Fountain Valley, California) |
| ABSTRACT | Quinolines, polyquinolines, polybenzoquinolines, molecular segments of fullerenes and graphene nanoribbons, and graphene nanoribbons and processes for producing such materials are provided. The processes utilize a form of an aza-Diels-Alder (Povarov) reaction to first form quinolines and/or polyquinolines. In some such embodiments polyquinolines thus produced are used to form graphene nanoribbon precursors, and molecular segments and graphene nanoribbons. In many such embodiments the graphene nanoribbone precursors are formed from polybenzoquinolines. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/156403 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/152 (20170801) C01B 32/182 (20170801) Acyclic or Carbocyclic Compounds C07C 5/02 (20130101) Heterocyclic Compounds C07D 215/04 (20130101) C07D 215/06 (20130101) Original (OR) Class C07D 215/12 (20130101) C07D 215/18 (20130101) C07D 221/06 (20130101) C07D 221/12 (20130101) C07D 401/14 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/7862 (20130101) C08G 73/0688 (20130101) Compositions of Macromolecular Compounds C08L 79/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946027 | Lee |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Chi-Hwan Lee (West Lafayette, Indiana) |
| ABSTRACT | Systems and methods for monitoring and tracking the behavior of cells and tissues in a culturing medium, for example, in a cell culture medium or an in vivo tissue environment, using a tissue scaffold system having one or more sensor arrays. Such monitoring systems include a tissue scaffold system and one or more sensor arrays on the tissue scaffold system in vertically stackable configurations. The sensor array(s) are configured to monitor electrical impedance and/or electrophysiological activities of cells or tissues which may be provided to an external data acquisition system for production of a three-dimensional (3D) map. |
| FILED | Tuesday, May 26, 2020 |
| APPL NO | 16/883427 |
| ART UNIT | 1799 — Organic Chemistry |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 1/3407 (20130101) Original (OR) Class C12M 21/08 (20130101) C12M 23/56 (20130101) C12M 25/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 2513/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/4836 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946040 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Julian Grunewald (Charlestown, Massachusetts); Ronghao Zhou (Charlestown, Massachusetts) |
| ABSTRACT | Engineered adenine base editor (ABE) variants with reduced RNA editing activity, and methods of using the same. |
| FILED | Tuesday, February 04, 2020 |
| APPL NO | 16/781979 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1024 (20130101) Original (OR) Class Enzymes C12Y 305/04004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946110 | Lloyd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Labortary (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey T. Lloyd (Aberdeen, Maryland); Phillip A. Jannotti (Baltimore, Maryland); Daniel J. Magagnosc (Baltimore, Maryland) |
| ABSTRACT | A metal structure includes an alloy material containing structural deformation twins embedded during a manufacturing process of the alloy material along defined directions, a defined deformation sequence, and defined strain levels. The embedded structural deformation twins mitigate failure and fracture in the alloy material. |
| FILED | Friday, July 10, 2020 |
| APPL NO | 16/925697 |
| ART UNIT | 1738 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 7/10 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/06 (20130101) C22F 1/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946128 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures, Inc. (Lincoln, Nebraska) |
| INVENTOR(S) | Yongfeng Lu (Lincoln, Nebraska); Leimin Deng (Lincoln, Nebraska); Chenfei Zhang (Qingdao, China PRC); Shiding Sun (Beijing, China PRC); Lei Liu (Lincoln, Nebraska) |
| ABSTRACT | A method for desensitizing a metal alloy such as an aluminum (Al) alloy is presented. The surface of the alloy is treated by controlled laser beam irradiation. The scanning laser beam heats the alloy to reach a relative low temperature between a solvus temperature and a soften/annealing temperature of the metal alloy to controllably reduce the degree of sensitization (DOS) of the metal alloy. The locally rapid heating and cooling effects produced by scanning the laser can improve the future sensitization resistance of the metal alloy, reduce the average desensitization temperature applied, and maintain the mechanical properties of Al alloy at the same time. |
| FILED | Friday, February 28, 2020 |
| APPL NO | 16/804616 |
| ART UNIT | 1738 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946162 | Zhao et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Dehua Zhao (Brookline, Massachusetts); Christopher A. Voigt (Belmont, Massachusetts); Michael Joseph Smanski (Falcon Heights, Minnesota) |
| ABSTRACT | The invention relates to methods and products for generating diverse libraries of genetic material. The products include libraries and constructed nucleic acids as well as kits and databases and systems thereof. |
| FILED | Wednesday, March 17, 2021 |
| APPL NO | 17/204219 |
| ART UNIT | 1675 — Semiconductors/Memory |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/66 (20130101) C12N 15/1034 (20130101) C12N 15/1058 (20130101) C12N 15/1093 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) C40B 40/08 (20130101) C40B 50/06 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/20 (20190201) G16B 20/30 (20190201) G16B 35/00 (20190201) G16B 35/10 (20190201) G16B 35/20 (20190201) G16B 40/00 (20190201) G16B 50/00 (20190201) G16B 50/30 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/60 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946379 | Heeter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Robert W. Heeter (Noblesville, Indiana); Daniel E. Molnar, Jr. (Lebanon, Indiana) |
| ABSTRACT | A fan case assembly adapted for use with a gas turbine engine includes a fan track liner and an annular case. The fan track liner extends circumferentially at least partway about a central axis of the gas turbine engine. The annular case is configured to support the fan track liner at a radial position relative to the central axis. The fan case assembly further includes an air recirculation duct configured to redirect air around the fan track liner. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 17/560230 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 21/045 (20130101) Original (OR) Class F01D 25/24 (20130101) Jet-propulsion Plants F02K 3/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/36 (20130101) F05D 2240/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946392 | Slipper et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Michael E. Slipper (Ridley Park, Pennsylvania); Tristan M. Wolfe (Philadelphia, Pennsylvania); Kyle J. Verrinder (West Chester, Pennsylvania) |
| ABSTRACT | A flow control device for constraining fluid flow between axial flow turbomachines in series has a flow constrainer which constrains the fluid flow downstream of the first turbomachine in the series to the blades region of the second turbomachine, preventing fluid flow from impacting the hub or nosecone of the second turbomachine and providing more uniform fluid flow to the second turbomachine. The flow control device includes connective elements for positioning between the downstream region of the first turbomachine and the upstream region of the second turbomachine. The device may be equipped with stator vanes having a variety of optional configurations to further improve the uniformity of the fluid flow load on the second turbomachine. |
| FILED | Wednesday, January 18, 2023 |
| APPL NO | 18/155930 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/041 (20130101) Original (OR) Class Non-positive-displacement Pumps F04D 23/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946414 | Heeter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce Corporation (Indianapolis, Indiana); Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana); Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Robert W. Heeter (Noblesville, Indiana); Christopher D. Hall (Indianapolis, Indiana); Daniel E. Molnar, Jr. (Lebanon, Indiana) |
| ABSTRACT | An acoustic panel for a gas turbine engine, includes a panel body, a panel-body cover, and a support bracket. The panel body is configured to dampen vibrations caused by the gas turbine engine. The forward support bracket is configured to mount the acoustic panel to portions of the gas turbine engine. |
| FILED | Thursday, December 16, 2021 |
| APPL NO | 17/553700 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/045 (20130101) Original (OR) Class Jet-propulsion Plants F02K 1/827 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2260/963 (20130101) F05D 2300/121 (20130101) F05D 2300/603 (20130101) F05D 2300/612 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/168 (20130101) G10K 11/172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946717 | Speirs et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Nathan B Speirs (Newport, Rhode Island); Jesse L Belden (Dighton, Massachusetts); Aren M Hellum (Wakefield, Rhode Island) |
| ABSTRACT | Methods and systems are provided for a pressurized gas launcher. The pressurized gas launcher includes a pressure source providing a quantity of high-pressure gas, a launcher barrel having a first end and a second end having an opening, and a bladder. The bladder is housed within the launcher barrel and selectively fluidically coupled to the pressure source. When filled with pressurized gas, the bladder plastically deforms. The gas launcher further includes a projectile housed within the launcher barrel with the bladder positioned between the first end of the launcher barrel and the projectile. The projectile is dischargeable from the launcher barrel when the bladder ruptures when gas in the bladder exceeds a pressure threshold. |
| FILED | Wednesday, September 21, 2022 |
| APPL NO | 17/949505 |
| ART UNIT | 3711 — Amusement and Education Devices |
| CURRENT CPC | Weapons for Projecting Missiles Without Use of Explosive or Combustible Propellant Charge; Weapons Not Otherwise Provided for F41B 11/62 (20130101) F41B 11/681 (20130101) F41B 11/723 (20130101) Original (OR) Class Apparatus for Launching Projectiles or Missiles From Barrels, e.g Cannons; Launchers for Rockets or Torpedoes; Harpoon Guns F41F 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946832 | Posada |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Natalia Posada (Dayton, Ohio) |
| ABSTRACT | A portable tracer fluid injection system. The system has a vapor cloud generator which vaporizes a vapor cloud generating liquid. The vapor cloud generator is uses a sub-ohm resistive heater to vaporize small volumes of the vapor cloud generating liquid, allowing for a relatively small tracer fluid injection system. This system has the benefit of being able to target specific regions of a test object within a wind tunnel and being usable for different positions within the test section of a wind tunnel. |
| FILED | Monday, April 10, 2023 |
| APPL NO | 18/297674 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 9/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946851 | Jalali et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Bahram Jalali (Los Angeles, California); Eric D. Diebold (Los Angeles, California); Brandon Buckley (Los Angeles, California) |
| ABSTRACT | An imaging flow cytometry apparatus and method which allows registering multiple locations across a cell, and/or across multiple flow channels, in parallel using radio-frequency-tagged emission (FIRE) coupled with a parallel optical detection scheme toward increasing analysis throughput. An optical source is modulated by multiple RF frequencies to produce an optical interrogation beam having a spatially distributed beat frequency. This beam is directed to one or more focused streams of cells whose responsive fluorescence, in different frequencies, is registered in parallel by an optical detector. |
| FILED | Monday, March 06, 2023 |
| APPL NO | 18/117708 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 15/1459 (20130101) G01N 15/1484 (20130101) G01N 21/64 (20130101) G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 33/537 (20130101) G01N 2015/1006 (20130101) G01N 2015/1477 (20130101) G01N 2021/6421 (20130101) G01N 2201/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946927 | Yacyshyn et al. |
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| FUNDED BY |
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| APPLICANT(S) | MUSIDORA BIOTECHNOLOGY LLC (Cincinnati, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bruce R. Yacyshyn (Cincinnati, Ohio); Mary E. Yacyshyn (Cincinnati, Ohio) |
| ABSTRACT | A process and system directed to a more effective, individual based treatment regimen which is built on clinical identified predictive target biomarkers associated with predicting the risk of an individual developing IBD and includes one or more predictive panels of prediction target biomarkers that are used to determine the risk of an individual developing IBD for determining if a therapy should be administered to reduce the risk and further determines the efficacy of treating the individual with mesalamine and effectively identifies and validates novel drug targets for new IBD therapeutics, new diagnostics and diagnostics standards for IBD therapeutic strategies. |
| FILED | Tuesday, August 20, 2019 |
| APPL NO | 16/545349 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/196 (20130101) A61K 31/606 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/492 (20130101) Original (OR) Class G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/065 (20130101) G01N 2800/067 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946928 | Xu et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (, None); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (, None) |
| INVENTOR(S) | Ke Xu (Cambridge, Massachusetts); Marc E. Lenburg (Brookline, Massachusetts); Ehab Billatos (Milton, Massachusetts); Alejandro A. Diaz (Boston, Massachusetts) |
| ABSTRACT | Described herein are methods relating to the diagnosis, prognosis, and treatment of airway dysfunction, e.g., bronchiectasis by detecting gene expression in a sample obtained from a subject. Exemplary samples include a bronchial brushing, nasal brushing, sputum, or peripheral blood sample. |
| FILED | Thursday, May 19, 2022 |
| APPL NO | 17/748404 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2539/10 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5023 (20130101) Original (OR) Class G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11947006 | Snyder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wendy E Snyder (Bremerton, Washington); Forrest N French (Poulsbo, Washington); Stephen John Leahu (Poulsbo, Washington) |
| ABSTRACT | Systems and methods are provided to detect and identify targeted objects buried in the seabed. A targeted area of the seabed may be scanned with a sub-bottom profiler based on predetermined parameters. A localization engine may model the sub-bottom profiler data using a Levenberg-Marquardt non-linear least squares determination. Distance measurements may be extracted based on the modeled data, including a vertical range based on a slant range measured from the sub-bottom profiler to the closest points on the exterior of the targeted objects. The location of the targeted objects may be based on the extracted measurements. In some embodiments, the sub-bottom profiler may be mounted on an unmanned underwater vehicle having thrusters to navigate the vehicle toward the targeted area to excavate and sidescan the targets object. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/531704 |
| ART UNIT | 3617 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 2008/002 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/101 (20130101) G01S 15/8902 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11947655 | Al-Gharaibeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Minneapolis, Minnesota) |
| ASSIGNEE(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Minneapolis, Minnesota) |
| INVENTOR(S) | Jafar Al-Gharaibeh (Eden Prairie, Minnesota); Ryan Lee Hagelstrom (Chaska, Minnesota); Jordan C. Bonney (Bloomington, Minnesota) |
| ABSTRACT | A computing device may authenticate a user of the computing device as an authorized user. The computing device may, in response to authenticating the user of the computing device as the authorized user, transition from a locked state to an unlocked state. The computing device may, in response to authenticating the user of the computing device as the authorized user, determine one or more computing devices that are proximate to the computing device. The computing device may, in response to determining the one or more computing devices that are proximate to the computing device, send to each of the one or more computing devices an indication of successful user authentication by the computing device to enable each of the one or more computing devices to transition from the locked state to the unlocked state without performing user authentication. |
| FILED | Tuesday, February 02, 2021 |
| APPL NO | 17/165511 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/41 (20130101) Original (OR) Class G06F 2221/2111 (20130101) G06F 2221/2113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11947663 | Sethumadhavan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Lakshminarasimhan Sethumadhavan (Niskayuna, New York); Miguel Arroyo (New York, New York); Mohamed Tarek Bnziad Mohamed Hassan (New York, New York); Evgeny Manzhosov (New York, New York) |
| ABSTRACT | Disclosed are methods, systems, devices, media, circuits, and other implementations, including a method that includes generating for a code block of a process executing on a controller-based device one or more code block copies defined in a virtual address space of the controller-based device, with the code block of the process being stored in a particular segment of a physical address space of the controller-based device, and with the code block configured to separately map to each of the one or more of the code block copies in the virtual address space. The method further includes processing at least a portion of one of the one or more code block copies defined in the virtual address space when the corresponding code block of the process is to be processed. |
| FILED | Thursday, September 24, 2020 |
| APPL NO | 17/030785 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/53 (20130101) G06F 21/54 (20130101) Original (OR) Class G06F 2221/2135 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11948300 | Fan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPECTRAL MD, INC. (Dallas, Texas) |
| ASSIGNEE(S) | Spectral MD, Inc. (Dallas, Texas) |
| INVENTOR(S) | Wensheng Fan (Plano, Texas); John Michael DiMaio (Dallas, Texas); Jeffrey E. Thatcher (Irving, Texas); Peiran Quan (Dallas, Texas); Faliu Yi (Allen, Texas); Kevin Plant (Dallas, Texas); Ronald Baxter (Grand Prairie, Texas); Brian McCall (Dallas, Texas); Zhicun Gao (Plano, Texas); Jason Dwight (Dallas, Texas) |
| ABSTRACT | Machine learning systems and methods are disclosed for prediction of wound healing, such as for diabetic foot ulcers or other wounds, and for assessment implementations such as segmentation of images into wound regions and non-wound regions. Systems for assessing or predicting wound healing can include a light detection element configured to collect light of at least a first wavelength reflected from a tissue region including a wound, and one or more processors configured to generate an image based on a signal from the light detection element having pixels depicting the tissue region, determine reflectance intensity values for at least a subset of the pixels, determine one or more quantitative features of the subset of the plurality of pixels based on the reflectance intensity values, and generate a predicted or assessed healing parameter associated with the wound over a predetermined time interval. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/177493 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0077 (20130101) A61B 5/445 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20081 (20130101) G06T 2207/30088 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11948855 | Simon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| ASSIGNEE(S) | Rockwell Collins, Inc. (Cedar Rapids, Iowa) |
| INVENTOR(S) | Bret W. Simon (West Liberty, Iowa); Jacob R. Mauermann (Marion, Iowa); Mark T. Dimke (Cedar Rapids, Iowa); Kaitlyn M. Fisher (Cedar Rapids, Iowa) |
| ABSTRACT | An integrated circuit (IC) package comprises a substrate having an outer portion close to the perimeter of the substrate, an inner portion surrounded by the outer portion, and an upper surface incorporating a wiring layer for the bonding of a semiconducting die (e.g., via its bottom face). The IC package includes a metallic or otherwise thermally conductive heat spreader thermally bonded on an inner surface of a boss on its bottom side to the top surface of the semiconducting die, and extending on its top surface to the edges of the substrate to maximize heat dissipation from the die. The boss extends toward the semiconducting die and is thermally coupled to the top face of the semiconducting die. |
| FILED | Tuesday, May 03, 2022 |
| APPL NO | 17/736002 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/42 (20130101) H01L 23/367 (20130101) Original (OR) Class H01L 23/3128 (20130101) H01L 23/3675 (20130101) H01L 25/0655 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11949136 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zhongyang Wang (St. Louis, Missouri); Vijay K. Ramani (St. Louis, Missouri); Shrihari Sankarasubramanian (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Zhongyang Wang (St. Louis, Missouri); Vijay K. Ramani (St. Louis, Missouri); Shrihari Sankarasubramanian (St. Louis, Missouri) |
| ABSTRACT | Described herein are direct liquid fuel cells with an alkaline anodic fuel stream including a solution of liquid fuel such as alcohols, ethers, glycols or compounds of hydrazine, and an acidic cathode oxidant stream including a solution of a suitable oxidant such as hydrogen peroxide or a gas steam with 1% to 100% O2. These cells are used as primary stationary and/or mobile power sources and also function in a secondary role as range extenders when coupled with a primary power source. |
| FILED | Tuesday, October 27, 2020 |
| APPL NO | 17/081174 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/083 (20130101) Original (OR) Class H01M 8/1004 (20130101) H01M 2300/0014 (20130101) H01M 2300/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11949211 | Sheik-Bahae et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mansoor Sheik-Bahae (Albuquerque, New Mexico); Alexander Robert Albrecht (Albuquerque, New Mexico); Zhou Yang (Albuquerque, New Mexico) |
| ABSTRACT | A vertical-external-cavity surface-emitting laser (VECSEL) and a method of forming the VECSEL is disclosed. The VECSEL includes a heat sink; a heat spreader or heat spreader formed on a top surface of the heat sink, where the heat spreader comprises a first material having a first refractive index; and a high contrast grating formed on a top surface of the heat spreader or active region, wherein the high contrast grating comprises an active region and the high contrast grating comprising a second material having a second refractive index, the second refractive index is greater than the first refractive index. |
| FILED | Thursday, September 19, 2019 |
| APPL NO | 17/277669 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/041 (20130101) H01S 5/1838 (20130101) H01S 5/02355 (20210101) H01S 5/02469 (20130101) Original (OR) Class H01S 5/02484 (20130101) H01S 5/3013 (20130101) H01S 5/18361 (20130101) H01S 5/18386 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11949458 | Seeley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SEQUENT LOGIC, LLC (Logan, Utah) |
| ASSIGNEE(S) | SEQUENT LOGIC, LLC (Logan, Utah) |
| INVENTOR(S) | Ryan Seeley (North Logan, Utah); Rhett H. Redd (Logan, Utah) |
| ABSTRACT | Apparatuses and methods for optical code-delay reflectometry (OCoDR) are disclosed. An apparatus includes a modulator, a receiver, and control circuitry. The modulator is configured to receive incident electromagnetic (EM) radiation at a substantially fixed frequency generated by one or more EM radiation sources. The incident EM radiation includes continuous-wave EM radiation. The modulator is configured to impart a sequence onto an amplitude, a phase, or both of the incident EM radiation to generate modulated EM radiation. The modulated EM radiation includes continuous-wave EM radiation. The receiver is configured to receive reference EM radiation. The receiver is also configured to receive reflected EM radiation from an optical system responsive to the modulated EM radiation and generate interfered EM radiation responsive to the reference EM radiation and the reflected EM radiation. The receiver is further configured to generate a continuous interferogram responsive to the interfered EM radiation. |
| FILED | Wednesday, July 20, 2022 |
| APPL NO | 17/813831 |
| ART UNIT | 2634 — Digital Communications |
| CURRENT CPC | Transmission H04B 10/071 (20130101) H04B 10/532 (20130101) Original (OR) Class H04B 10/614 (20130101) Multiplex Communication H04J 13/0062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11949544 | Melodia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Tommaso Melodia (Newton, Massachusetts); Francesco Restuccia (Boston, Massachusetts) |
| ABSTRACT | A polymorphic platform for wireless communication systems is provided that employs trained classification techniques to determine physical layer parameters from a transmitter at a receiver. The system includes a learning module to determine transmitted physical layer parameters of the signal using a trained classification module, such as a deep learning neural network. The trained classification module receives I/Q input samples from receiver circuitry and processes the I/Q input samples to determine transmitted physical layer parameters from the transmitter. The system includes a polymorphic processing unit that demodulates data from the signal based on the determined transmitted parameters. |
| FILED | Monday, February 24, 2020 |
| APPL NO | 17/604476 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) G06N 3/063 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/34 (20130101) Original (OR) Class H04L 27/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11949595 | Levitt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Yonatan Meir Levitt (Brookline, Massachusetts); Gaspar Mora Porta (Campbell, California) |
| ABSTRACT | An apparatus includes a first set of processing element nodes, the first set of processing element nodes defining a first hierarchy of processing element nodes, the first set of processing element nodes comprising a source node, a first look-up table (LUT), and a first forwarder node, the source node to communicate with the first forwarder node by a first virtual channel. The apparatus includes a second set of processing element nodes, the second set of processing element nodes defining a second hierarchy of processing element nodes, the second set of processing element nodes comprising a second forwarder node, a second LUT, the second LUT comprising an indication of a direction of the first forwarder node in the first hierarchy, and a target node logically coupled to the second forwarder node by the first virtual channel. The first LUT comprises a direction of the second forwarder node in the second hierarchy. |
| FILED | Friday, June 26, 2020 |
| APPL NO | 16/913433 |
| ART UNIT | 2413 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/4675 (20130101) H04L 45/34 (20130101) H04L 45/742 (20130101) H04L 45/7453 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11950394 | Rush et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GE AVIATION SYSTEMS LLC (Grand Rapids, Michigan) |
| ASSIGNEE(S) | GE Aviation Systems LLC (Grand Rapids, Michigan) |
| INVENTOR(S) | Brian Magann Rush (Niskayuna, New York); Christopher James Kapusta (Delanson, New York); David Richard Esler (Gloversville, New York); Liang Yin (Clifton Park, New York); Richard Anthony Eddins (Margate, Florida); Judd Everett Swanson (Margate, Florida); Liqiang Yang (Coral Springs, Florida) |
| ABSTRACT | The disclosure relates to an apparatus and method for liquid cooling of an electronic component. A housing includes an insertion slot and defines at least one component chamber for carrying the electronic component. A fluid inlet and fluid outlet are provided on the housing. A liquid coolant circuit passes through the housing at least from the inlet to the outlet. |
| FILED | Tuesday, October 12, 2021 |
| APPL NO | 17/499324 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/4735 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20272 (20130101) H05K 7/20345 (20130101) Original (OR) Class H05K 7/20936 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11950509 | Sperry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Technology Applications, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | Technology Applications, Inc. (Boulder, Colorado) |
| INVENTOR(S) | Brian Sperry (Boulder, Colorado); Trevor Sperry (Firestone, Colorado); Jamie Eyre (Boulder, Colorado) |
| ABSTRACT | The present invention provides heat exchanger systems, and associated methods, using thermally anisotropic carbon fiber materials, preferably woven graphite fiber sheets, where convection is used to transfer heat from the heat exchanger to a lower temperature fluid, such as circulating air or cooling liquid. |
| FILED | Friday, November 29, 2019 |
| APPL NO | 16/699381 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 21/02 (20130101) Electric solid-state devices not otherwise provided for H10N 10/13 (20230201) Original (OR) Class H10N 10/17 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11944982 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jian Liu (Richland, Washington); B. Peter McGrail (Pasco, Washington); Satish Nune (Richland, Washington); Praveen Thallapally (Richland, Washington) |
| ABSTRACT | Disclosed herein are embodiments of a polymer-functionalized particle for using in isolating and extracting solutes, such as rare earth metals, lithium, and the like. The polymer-functionalized particles exhibit strong resistance to agglomeration and degradation even in high ionic strength and/or temperature environments. A post-particle synthesis method for making the polymer-functionalized particle is disclosed, along with a magnetic separation device and that can be used in system embodiments to facilitate use and regeneration of the polymer-functionalized particles in solute extraction. |
| FILED | Monday, January 13, 2020 |
| APPL NO | 16/741388 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/203 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/01 (20130101) B03C 1/30 (20130101) Original (OR) Class B03C 1/288 (20130101) B03C 1/0335 (20130101) B03C 2201/18 (20130101) B03C 2201/20 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 28/02 (20130101) C08F 128/02 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/0206 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/047 (20130101) H01F 1/0054 (20130101) H01F 1/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945151 | Rodriguez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jennifer Nicole Rodriguez (Fremont, California); Eric B. Duoss (Dublin, California); James Lewicki (Oakland, California); Christopher Spadaccini (Oakland, California); Thomas S. Wilson (Oakland, California); Cheng Zhu (Livermore, California) |
| ABSTRACT | An additive manufacturing apparatus includes an additive manufacturing print head and a nozzle that receives a bio-based shape memory polymer material and a bio-based material. The nozzle extrudes the bio-based shape memory polymer material and the bio-based material onto a substrate to form a bio-based shape memory polymer part or product. |
| FILED | Tuesday, August 16, 2022 |
| APPL NO | 17/820144 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) Original (OR) Class B29C 64/165 (20170801) B29C 64/209 (20170801) B29C 64/321 (20170801) B29C 64/393 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) B29K 2105/124 (20130101) B29K 2507/04 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 70/10 (20200101) B33Y 80/00 (20141201) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/046 (20170501) C08K 7/04 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 63/00 (20130101) C08L 91/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945764 | Jansone-Popova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Santa Jansone-Popova (Knoxville, Tennessee); Ilja Popovs (Knoxville, Tennessee) |
| ABSTRACT | A method for producing a diglycolamide molecule having the formula: wherein R1 and R2 are independently selected from alkyl groups (R) and acyl groups (C(O)R) in which the alkyl groups (R) contain 1-30 carbon atoms and optionally contain an ether or thioether linkage between carbon atoms, and R5 and R6 are independently selected from hydrogen atom and alkyl groups containing 1-3 carbon atoms; and one or both pairs of R1 and R2 are optionally interconnected to form a ring; the method comprising: combining a diglycolic acid molecule (A) and a secondary amine (B) to form a salt intermediate (C), and heating the salt intermediate (C) to a temperature of 100° C. to 300° C. to form the diglycolamide of Formula (1) in a dehydration process, wherein the method is shown schematically as follows: |
| FILED | Wednesday, June 08, 2022 |
| APPL NO | 17/835028 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 231/02 (20130101) Original (OR) Class Heterocyclic Compounds C07D 207/12 (20130101) C07D 211/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945947 | Saito et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Tomonori Saito (Knoxville, Tennessee); Zhengping Zhou (Westford, Massachusetts); Md Anisur Rahman (Knoxville, Tennessee) |
| ABSTRACT | A crosslinked polymeric composition comprising A, B, C, D, and E units having the following structures, respectively: and wherein dashed bonds represent optional bonds; the asterisks (*) in C units represent covalent bond connection points with asterisks in A units and E units; the asterisks (*) in D units represent covalent bond connection points with asterisks in B units and E units; wherein a portion of E units are bound to C units, a portion of E units are bound to D units, and a portion of E units are bound to both C and D units; and the composition contains a multiplicity of A, B, C, D, and E units. Also described is a method for producing the crosslinked polymeric composition by reacting epoxy-containing molecules (A molecules), isocyanate-containing molecules (B molecules), and disulfide-containing molecules (C molecules). |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/138277 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/58 (20130101) C08G 18/73 (20130101) C08G 18/3857 (20130101) C08G 18/3863 (20130101) C08G 18/8054 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) Compositions of Macromolecular Compounds C08L 75/02 (20130101) Original (OR) Class C08L 2201/06 (20130101) C08L 2312/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945985 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Jian Li (Tempe, Arizona); Jiang Wu (Chandler, Arizona) |
| ABSTRACT | Compounds of General Formula I may harvest electrogenerated excitons via metal-assisted delayed fluorescence (MADF). The compounds have utility in light emitting diodes and light emitting devices. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/316800 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/006 (20130101) C07F 15/0086 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class C09K 2211/1007 (20130101) C09K 2211/1014 (20130101) C09K 2211/1022 (20130101) C09K 2211/1029 (20130101) C09K 2211/1044 (20130101) C09K 2211/1051 (20130101) C09K 2211/1059 (20130101) C09K 2211/1074 (20130101) Organic electric solid-state devices H10K 50/11 (20230201) H10K 85/341 (20230201) H10K 85/346 (20230201) H10K 2101/10 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946139 | Mane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Anil U. Mane (Naperville, Illinois); Devika Choudhury (Naperville, Illinois); Jeffrey W. Elam (Elmhurst, Illinois) |
| ABSTRACT | A lithium boron coating and a method of producing the same. Atomic layer deposition deposits lithium and boron to form a lithium borate layer. The lithium borate maybe deposited as a solid electrolyte. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/039822 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/38 (20130101) C23C 16/4408 (20130101) C23C 16/45534 (20130101) C23C 16/45553 (20130101) C23C 16/45555 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0562 (20130101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946160 | Britt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MATRIX SENSORS, INC. (San Diego, California) |
| ASSIGNEE(S) | Matrix Sensors, Inc (San Diego, California) |
| INVENTOR(S) | David K Britt (El Cerrito, California); Paul R Wilkinson (El Segundo, California); Steven Yamamoto (San Diego, California) |
| ABSTRACT | An apparatus and method is provided for coating a surface of a material with a film of porous coordination polymer. A first substrate having a first surface to be coated is positioned in a processing chamber such that the first surface is placed in a substantially opposing relationship to a second surface. In some embodiments, the second surface is provided by a wall of the processing chamber, and in other embodiments the second surface is provided by a second substrate to be coated. The first substrate is held such that a gap exists between the first and second surfaces, and the gap is filled with at least one reaction mixture comprising reagents sufficient to form the crystalline film on at least the first surface. A thin gap (e.g., having a thickness less than 2 mm) between the first and second surfaces is effective for producing a high quality film having a thickness less than 100 μm. Confining the volume of the reaction mixture to a thin layer adjacent the substrate surface significantly reduces problems with sedimentation and concentration control. In some embodiments, the size, shape, or average thickness of the gap is adjusted during formation of the film in response to feedback from at least one film growth monitor. |
| FILED | Saturday, April 01, 2023 |
| APPL NO | 18/129829 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/00 (20130101) C07F 15/04 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 28/04 (20130101) Original (OR) Class C30B 29/58 (20130101) Weighing G01G 3/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946434 | Zimmerman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INNIO Waukesha Gas Engines Inc. (Waukesha, Wisconsin) |
| ASSIGNEE(S) | Innio Jenbacher GmbH and Co OG (Jenbach, Austria) |
| INVENTOR(S) | Daniel David Zimmerman (Waterford, Wisconsin) |
| ABSTRACT | A system includes a piston assembly. The piston assembly includes a crown portion having a crown, an outer wall coupled to the crown, a first inner wall disposed inside of the outer wall, a first fluid chamber disposed radially between the outer wall and the first inner wall, and an angled wall insert. An opening extends into the first fluid chamber in an axially inward direction. The outer wall, the first inner wall, the first fluid chamber, the opening, and the angled wall insert extend circumferentially about a central axis of the piston assembly. The angled wall insert is disposed in the opening, and the first fluid chamber is disposed axially between the crown and the angled wall insert. |
| FILED | Wednesday, February 08, 2023 |
| APPL NO | 18/107463 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cooling of Machines or Engines in General; Cooling of Internal-combustion Engines F01P 3/06 (20130101) Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 3/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946504 | Whalen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Scott A. Whalen (West Richland, Washington); Tianhao Wang (Richland, Washington); Piyush Upadhyay (Richland, Washington); Keerti S. Kappagantula (Richland, Washington) |
| ABSTRACT | Riveted assemblies are provided that can include a substrate extending between two ends to define opposing substrate surfaces having a first opening extending between the opposing substrate surfaces; a metal-comprising substrate extending between two ends to define opposing metal-comprising substrate surfaces having a second opening extending between the opposing metal-comprising substrate surfaces. The riveted assemblies can further provide that the first and second openings complement one another when the substrate and metal-comprising substrate are engaged; and a rivet shaft extends through the openings and engages the substrate with the rivet head and the metal-comprising substrate with the rivet stop head, at least a portion of the stop head being mixed with, and forming a metallurgical bond with the metal-comprising substrate. Assemblies are provided that can include a rivet stop head mixed with, and metallurgically bonded with a metal-comprising substrate. Methods for affixing substrates to one another are also provided. The methods can include providing a substrate defining an opening configured to receive a rivet shaft; providing a metal-comprising substrate defining a complimentary opening; operatively engaging the substrates with the rivet shaft; and forming a stop head from the rivet shaft to affix the substrates. The method further includes that the stop head mixes with, and forms a metallurgical bond with the metal-comprising substrate. Methods for mixing materials to form a metallurgical bond are also provided. The methods can include forming a metallurgical bond between a stop head of a rivet and a metal-comprising substrate. |
| FILED | Thursday, November 03, 2022 |
| APPL NO | 17/979772 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Forging; Hammering; Pressing Metal; Riveting; Forge Furnaces B21J 15/02 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946834 | Junghans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Ann Junghans (Los Alamos, New Mexico); Eric Davis (Los Alamos, New Mexico); Cristian Pantea (Los Alamos, New Mexico); Rollin Lakis (Los Alamos, New Mexico); Vlad Henzl (Los Alamos, New Mexico) |
| ABSTRACT | A method of sample collection includes collecting an analyte from a sampling surface using a rapidly curable liquid gel comprising one or more metal particles; co-aggregating the one or more metal particles from the rapidly curable liquid gel and the analyte from the sampling surface; and rapidly curing the rapidly curable liquid gel. The composition and sample preparation conditions may facilitate improved collection efficiency of analytes during environmental and forensic evidence sampling. In addition, the composition and sample preparation conditions may facilitate enhanced detection and identification of the analyte using e.g., Surface Enhanced Raman Spectrometry (SERS). |
| FILED | Friday, October 29, 2021 |
| APPL NO | 17/514945 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/04 (20130101) Original (OR) Class G01N 1/36 (20130101) G01N 1/4077 (20130101) G01N 21/658 (20130101) G01N 33/227 (20130101) G01N 2001/028 (20130101) G01N 2001/4094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946871 | Shashurin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Alexey Shashurin (West Lafayette, Indiana); Xingxing Wang (West Lafayette, Indiana) |
| ABSTRACT | Methods and systems capable of measuring gas temperatures utilizing plasma discharges. Such a method performs a measurement of a temperature of a gas by generating a probing nanosecond plasma pulse in the gas, and then using an optical emission spectroscopy technique to measure the temperature of the gas by processing a light emission signal excited by the probing nanosecond plasma pulse. |
| FILED | Friday, October 30, 2020 |
| APPL NO | 17/085856 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/67 (20130101) Original (OR) Class G01N 21/1702 (20130101) G01N 2021/1704 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946895 | Shahrjerdi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Davood Shahrjerdi (New York, New York); Roozbeh Kiani (New York, New York); Ting Wu (New York, New York) |
| ABSTRACT | Principles for reliable manufacturing carbon-based electrodes with arbitrary sensitivity and homogeneity are provided. Specifically, the sensitivity of carbon-based electrodes can be engineered by changing the density of sp2 type defects present in a multilayer graphene film. The engineered carbon-based electrodes can be used as a passive sensing element in electrochemical measurement of a target analyte. Carbon-based electrodes are also disclosed that have sp2 hybridization and can include multilayer graphene films. The disclosed carbon-based electrodes have a density of zero-dimensional defects (i.e., point-like defects) which provides enhanced area-normalized sensitivity when used in sensing applications. The maximum area-normalized sensitivity is achieved at the point defect density of 4-5×1012 cm−2. |
| FILED | Tuesday, July 31, 2018 |
| APPL NO | 16/635634 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/308 (20130101) Original (OR) Class G01N 33/48707 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11947056 | Wiggins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Brenden W. Wiggins (Los Alamos, New Mexico); Markus Peter Hehlen (Los Alamos, New Mexico); James F. Hunter (Los Alamos, New Mexico) |
| ABSTRACT | A pixelated X-ray conversion screen includes a metal aperture sheet having a pixel hole filled with a scintillator material, wherein an area of the pixel hole is equal to or less than about 0.25 mm2. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/854961 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/2002 (20130101) Original (OR) Class G01T 1/2023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11947470 | Panas |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Robert Matthew Panas (Dublin, California) |
| ABSTRACT | A system is disclosed for controlling controllable elements of an external component. The system uses a state translator subsystem (“STS”) which receives a state command from an external subsystem. The STS has at least one module for processing the state command and generating operational commands, in parallel, over a first plurality of channels, to control the elements of the external component. A programmable calibration command translation layer subsystem (“PCCTL”) uses the operational commands to generate granular level commands for controlling the elements, and to transmit the granular level commands over a second plurality of channels. A subsystem is coupled between the PCCTL and the elements, which receives the commands from the PCCTL and uses the commands to generate final output commands, which are applied in parallel, over a third plurality of channels, to the elements. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244332 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 26/0833 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/021 (20130101) Electric Digital Data Processing G06F 13/37 (20130101) G06F 13/126 (20130101) Original (OR) Class G06F 15/825 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11948438 | Candy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Christopher Roland Candy (San Ramon, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); Christopher Roland Candy (San Ramon, California) |
| INVENTOR(S) | James Vincent Candy (Danville, California); Karl Albert Fisher (Brentwood, Canada); Christopher Roland Candy (San Ramon, California) |
| ABSTRACT | An event detection unit (EDU) for detecting an explosive event is provided. The EDU includes different types of sensors for measuring characteristics of an explosive event. The EDU includes an event notification component. The EDU also includes a processor that receives a measurement from the sensors and generates a combined non-event probability and a combined event probability based on that measurement that indicates a likelihood that an explosive event has not occurred or has occurred. The processor determines whether an explosive event has occurred based on the non-event probabilities and event probabilities. When an explosive event has been determined to occur, the processor directs the event notification component to output a notification that an explosive event has occurred. |
| FILED | Wednesday, November 30, 2022 |
| APPL NO | 18/072373 |
| ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
| CURRENT CPC | Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 3/10 (20130101) G08B 5/36 (20130101) G08B 17/08 (20130101) Original (OR) Class G08B 29/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11948662 | Erbilgin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Onur Erbilgin (Oakland, California); Benjamin P. Bowen (Walnut Creek, California); Trent R. Northen (Walnut Creek, California); Markus de Raad (Berkeley, California); Oliver Ruebel (Richmond, California) |
| ABSTRACT | Disclosed herein are systems and methods for associating metabolites with genes. In some embodiments, after potential metabolites are identified based on spectroscopy data of the content of an organism, possible reactions capable of producing the potential metabolites are determined. The possible reactions are compared to gene sequences in a database, and an association score for the likelihood that a gene sequence is related to the potential metabolites is calculated. |
| FILED | Friday, February 16, 2018 |
| APPL NO | 15/932459 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/00 (20130101) Electric Digital Data Processing G06F 16/903 (20190101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 20/00 (20190201) Original (OR) Class Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 70/60 (20180101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11948979 | Eichenfield et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Matt Eichenfield (Albuquerque, New Mexico); Lisa Anne Plucinski Hackett (Albuquerque, New Mexico) |
| ABSTRACT | An acoustoelectric amplifier and a number of corresponding devices are disclosed, along with methods for making the same. The acoustoelectric amplifier employs wafer-scale bonding to heterogeneously integrate an epitaxial III-V semiconductor stack and a piezoelectric layer. To increase the acoustic gain with low power dissipation, the electromechanical coupling coefficient (k2) of the piezoelectric layer should be high to increase the acoustoelectric interaction strength. The semiconductor mobility should be high to reduce the voltage required to increase the carrier drift velocity. The conductivity-thickness product should be low to prevent screening of the acoustoelectric interaction. The acoustoelectric amplifier or its corresponding material structure may be used to form circulators, isolators, oscillators, mixers, and correlators, while interconnecting waveguides may be formed of the piezoelectric layer or the semiconductor stack. An exemplary piezoelectric layer is formed of LiNbO3, while an exemplary semiconductor stack is formed of InGaAs/InP. |
| FILED | Wednesday, May 19, 2021 |
| APPL NO | 17/324399 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/205 (20130101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/383 (20130101) Amplifiers H03F 3/187 (20130101) H03F 2200/03 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/02574 (20130101) H03H 9/02976 (20130101) H03H 9/14514 (20130101) Electric solid-state devices not otherwise provided for H10N 30/8542 (20230201) H10N 39/00 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11949410 | Avestruz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Al-Thaddeus Avestruz (Ann Arbor, Michigan); Xiaofan Cui (Ann Arbor, Michigan) |
| ABSTRACT | A system includes control circuitry configured to control an output signal. The control circuitry and/or various other sources of undesirable signal components may corrupt the control signal used by the control circuitry to correct the output signal. Conditioning circuitry may effect current-domain repair on the control circuitry by providing feedback-based conditioning actuation, including comparator overdrive, to the control circuitry. |
| FILED | Monday, October 24, 2022 |
| APPL NO | 17/972218 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 5/22 (20130101) H03K 17/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11949458 | Seeley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SEQUENT LOGIC, LLC (Logan, Utah) |
| ASSIGNEE(S) | SEQUENT LOGIC, LLC (Logan, Utah) |
| INVENTOR(S) | Ryan Seeley (North Logan, Utah); Rhett H. Redd (Logan, Utah) |
| ABSTRACT | Apparatuses and methods for optical code-delay reflectometry (OCoDR) are disclosed. An apparatus includes a modulator, a receiver, and control circuitry. The modulator is configured to receive incident electromagnetic (EM) radiation at a substantially fixed frequency generated by one or more EM radiation sources. The incident EM radiation includes continuous-wave EM radiation. The modulator is configured to impart a sequence onto an amplitude, a phase, or both of the incident EM radiation to generate modulated EM radiation. The modulated EM radiation includes continuous-wave EM radiation. The receiver is configured to receive reference EM radiation. The receiver is also configured to receive reflected EM radiation from an optical system responsive to the modulated EM radiation and generate interfered EM radiation responsive to the reference EM radiation and the reflected EM radiation. The receiver is further configured to generate a continuous interferogram responsive to the interfered EM radiation. |
| FILED | Wednesday, July 20, 2022 |
| APPL NO | 17/813831 |
| ART UNIT | 2634 — Digital Communications |
| CURRENT CPC | Transmission H04B 10/071 (20130101) H04B 10/532 (20130101) Original (OR) Class H04B 10/614 (20130101) Multiplex Communication H04J 13/0062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11949762 | Edgar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Thomas W. Edgar (Richland, Washington); Sean J. Zabriskie (Seattle, Washington); Eric Y. Choi (Richland, Washington) |
| ABSTRACT | Apparatuses and methods for tapping serial communications and transforming the serial data into a format appropriate for routable networks are significant for purposes of security and troubleshooting, especially in critical infrastructure networks. Communication taps should be completely passive such that any failure would not interrupt the serial communications. Furthermore, automatic determination of unspecified serial protocol frames allow general implementation across various networks, or across devices within a single network, without the need to customize for each implementation. |
| FILED | Thursday, May 13, 2021 |
| APPL NO | 17/319420 |
| ART UNIT | 2463 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/30 (20130101) H04L 69/03 (20130101) Original (OR) Class H04L 69/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11950352 | Agustsson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RADIABEAM TECHNOLOGIES, LLC (Santa Monica, California) |
| ASSIGNEE(S) | RADIABEAM TECHNOLOGIES, LLC (Santa Monica, California) |
| INVENTOR(S) | Ronald Agustsson (Venice, California); Salime Boucher (Santa Monica, California); Sergey Kutsaev (Santa Monica, California) |
| ABSTRACT | A particle accelerator can include a first waveguide portion and a second waveguide portion. The first waveguide portion can include a first plurality of cell portions and a first iris portion that is disposed between two of the first plurality of cell portions. The first iris portion can include a first portion of an aperture such that the aperture is configured to be disposed about a beam axis. The first waveguide portion can further include a first bonding surface. The second waveguide portion can include a second plurality of cell portions and a second iris portion that is disposed between two of the second plurality of cell portions. The second iris portion can include a second portion of the aperture. The second waveguide portion can include a second bonding surface. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180458 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/127 (20130101) H01P 11/002 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/16 (20130101) Original (OR) Class H05H 7/22 (20130101) H05H 2007/225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11950435 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Kai Zhu (Littleton, Colorado); Jinhui Tong (Golden, Colorado); Qi Jiang (Lakewood, Colorado) |
| ABSTRACT | The present disclosure relates to a composition that includes a perovskite phase having the stoichiometry ABX3 and a perovskite-like phase having the stoichiometry A′2A″B′2X′, where A is a first cation, B is a second cation, X is a first anion, A′ is a third cation, A″ is a fourth cation, B′ is a fifth cation, X′ is a second anion, and A′ is different than A″. |
| FILED | Friday, July 22, 2022 |
| APPL NO | 17/814433 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Organic electric solid-state devices H10K 30/57 (20230201) Original (OR) Class H10K 85/50 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11950436 | Wheeler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Colorado School of Mines (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Lance Michael Wheeler (Golden, Colorado); Kevin Joseph Prince (Golden, Colorado); Colin Andrew Wolden (Denver, Colorado); Mirzojamshed M. Mirzokarimov (Lakewood, Colorado); Christopher Paul Muzzillo (Evergreen, Colorado) |
| ABSTRACT | The present disclosure relates to a device that includes an irregular network of interconnected ridges in physical contact with a planar substrate and a perovskite layer, where the planar substrate include a support layer and a first charge selective contact layer, the first charge selective contact layer is positioned between the support layer and the interconnected ridges, each ridge includes a second charge selective contact layer and an insulating layer, the insulating layer is positioned between the first charge selective contact layer and the second charge selective contact layer, and the perovskite layer substantially covers the plurality of interconnected ridges and the underlying planar substrate. |
| FILED | Monday, June 26, 2023 |
| APPL NO | 18/341473 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Organic electric solid-state devices H10K 30/40 (20230201) H10K 30/57 (20230201) Original (OR) Class H10K 30/85 (20230201) H10K 30/86 (20230201) H10K 71/12 (20230201) H10K 71/233 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11944423 | Sharma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Saransh Sharma (Pasadena, California); Mikhail Shapiro (Los Angeles, California); Azita Emami (Pasadena, California) |
| ABSTRACT | A method for in-vivo monitoring of a target internal volume of a mammal that includes: (a) placing the target internal volume proximal to a three-dimensional magnetic field generator; (b) generating first, second, and third magnetic field gradients along respective first, second, and third axes that are mutually orthogonal; (c) measuring first, second, and third magnetic fields with a three-dimensional magnetic sensor disposed in an ingestible capsule, the ingestible capsule disposed in the target internal volume; (d) with a controller in electrical communication with the three-dimensional magnetic sensor, generating a magnetic sensor output signal that encodes a measurement of the first, second, and third magnetic fields; (e) broadcasting the magnetic sensor output signal from an antenna disposed in the ingestible capsule, and (f) receiving the magnetic sensor output signal with a receiver. The received magnetic field data can be used to determine the three-dimensional position of the ingestible capsule. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/097421 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/073 (20130101) Original (OR) Class A61B 5/076 (20130101) A61B 5/6861 (20130101) A61B 2562/0223 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/31 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/022 (20130101) G01R 33/385 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944426 | Pearlman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jonathan L. Pearlman (Pittsburgh, Pennsylvania); Jonathan A. Duvall (Pittsburgh, Pennsylvania); Samuel T. Bucior (Greenboro, North Carolina) |
| ABSTRACT | A load cell apparatus includes a base member, a cap member, a number of first members provided between the base member and the cap member and forming at least a portion of a support wall of the load cell apparatus, and a plurality of strain gauges directly coupled to the number of first members, the plurality of strain gauges being positioned to measure an axial load applied to the load cell in a direction extending from the cap member to the base member. |
| FILED | Friday, January 11, 2019 |
| APPL NO | 16/959589 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1036 (20130101) Original (OR) Class A61B 5/6891 (20130101) A61B 5/6894 (20130101) A61B 2562/0252 (20130101) A61B 2562/0261 (20130101) Weighing G01G 3/14 (20130101) G01G 19/44 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/2231 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944451 | Mulligan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Flashback Technologies, Inc. (Boulder, Colorado); The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Isobel Jane Mulligan (Niwot, Colorado); Gregory Zlatko Grudic (Niwot, Colorado); Steven L. Moulton (Littleton, Colorado) |
| ABSTRACT | Novel tools and techniques for assessing, predicting and/or estimating effectiveness of fluid resuscitation of a patient and/or an amount of fluid needed for effective resuscitation of the patient, in some cases, noninvasively. |
| FILED | Tuesday, July 26, 2022 |
| APPL NO | 17/873691 |
| ART UNIT | 2459 — Computer Networks |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4836 (20130101) Original (OR) Class Electric Digital Data Processing G06F 16/289 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/01 (20220501) H04L 67/10 (20130101) H04L 67/1008 (20130101) H04L 67/5683 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944941 | Asatekin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Ayse Asatekin (Arlington, Massachusetts); Ilin Sadeghi (Arlington, Massachusetts) |
| ABSTRACT | Disclosed is a nanoporous membrane including a porous support layer and a selective layer. The selective layer, being deposited on a surface of the porous support layer, has an effective pore size smaller than that of the porous support layer and contains an array of polymeric nanoparticles that have on their surfaces a plurality of —C(═O)XR groups. Also disclosed are methods of fabricating a nanoporous membrane described above and using the nanoporous membrane for separating a mixture that contains two solutes. |
| FILED | Friday, April 26, 2019 |
| APPL NO | 17/050665 |
| ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 67/0093 (20130101) Original (OR) Class B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 71/32 (20130101) B01D 71/40 (20130101) B01D 71/82 (20130101) B01D 2323/36 (20130101) B01D 2323/38 (20130101) B01D 2325/02 (20130101) B01D 2325/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944966 | Aksimentiev |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Aleksei Aksimentiev (Urbana, Illinois) |
| ABSTRACT | Aspects of the subject disclosure may include, for example, an apparatus comprising: a membrane, wherein the membrane has a first side and a second side, wherein the membrane has a first pore disposed therein, wherein the first pore extends through the membrane from the first side of the membrane to the second side of the membrane, wherein the membrane has a second pore disposed therein, and wherein the second pore extends through the membrane from the first side of the membrane to the second side of the membrane; a first channel disposed on the first side of the membrane, wherein the first channel is along a first longitudinal axis; a second channel disposed on the first side of the membrane, wherein the second channel is along a second longitudinal axis, and wherein the first channel and the second channel are disposed side by side adjacent to each other; a third channel disposed on the second side of the membrane, wherein the third channel is along a third longitudinal axis, wherein the third channel is in first fluid communication with the first channel via the first pore, and wherein the third channel is in second fluid communication with the second channel via the second pore; and one or more sensors disposed at one or more locations to facilitate sequencing of a molecule that extends from the first channel, through the first pore across at least a portion of the third channel, and through the second pore into the second channel. Additional embodiments are disclosed. |
| FILED | Thursday, October 28, 2021 |
| APPL NO | 17/513516 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Original (OR) Class B01L 2200/0652 (20130101) B01L 2300/0663 (20130101) B01L 2300/0896 (20130101) B01L 2400/0415 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945107 | Lerner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona) |
| INVENTOR(S) | Zachary Forest Lerner (Flagstaff, Arizona); Greg Orekhov (Flagstaf, Arizona); Jason Luque (Flagstaff, Arizona) |
| ABSTRACT | A method of controlling a drive motor for a powered ankle exoskeleton is disclosed. The method includes modeling motor drive current as a linear function of desired torque and ankle angular velocity, and then controlling motor current as a function of measured torque and determined ankle angular velocity. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/207317 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) A61H 2003/007 (20130101) A61H 2201/123 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/1215 (20130101) A61H 2201/5061 (20130101) A61H 2201/5071 (20130101) A61H 2201/5097 (20130101) A61H 2205/106 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) Original (OR) Class B25J 9/163 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946159 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Chunghorng Liu (West Lafayette, Indiana); Siyu Liu (West Lafayette, Indiana) |
| ABSTRACT | A method of selectively controlling materials structure in solution based chemical synthesis and deposition of materials by controlling input energy from pulsed energy source includes determining solution conditions, searching and/or determining energy barrier(s) of a desired materials structure formation, applying precursor solution with selected solution condition onto a substrate, and applying determined input energy from a pulsed energy source with a selected condition to the substrate, thereby nucleating and growing the crystal. |
| FILED | Tuesday, November 22, 2022 |
| APPL NO | 17/992819 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/16 (20130101) Original (OR) Class C30B 29/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946162 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Dehua Zhao (Brookline, Massachusetts); Christopher A. Voigt (Belmont, Massachusetts); Michael Joseph Smanski (Falcon Heights, Minnesota) |
| ABSTRACT | The invention relates to methods and products for generating diverse libraries of genetic material. The products include libraries and constructed nucleic acids as well as kits and databases and systems thereof. |
| FILED | Wednesday, March 17, 2021 |
| APPL NO | 17/204219 |
| ART UNIT | 1675 — Semiconductors/Memory |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/66 (20130101) C12N 15/1034 (20130101) C12N 15/1058 (20130101) C12N 15/1093 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) C40B 40/08 (20130101) C40B 50/06 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/20 (20190201) G16B 20/30 (20190201) G16B 35/00 (20190201) G16B 35/10 (20190201) G16B 35/20 (20190201) G16B 40/00 (20190201) G16B 50/00 (20190201) G16B 50/30 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/60 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946452 | Hong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jiarong Hong (New Brighton, Minnesota); Linyue Gao (Minneapolis, Minnesota) |
| ABSTRACT | Control systems are described that mitigate the effects of icing events on wind turbines. Example methods include determining, with a control system, that an icing event has begun to affect the wind turbine; based on a determination that the icing event has begun to affect the wind turbine, changing a phase of the wind turbine with the control system to an operational-icing phase by modifying angles of attack of blades of the wind turbine via changing blade pitch angles, wherein the wind turbine continues to generate electrical power when the wind turbine is in the operational-icing phase; and based on a determination that electrical power generation of the wind turbine is below a threshold, changing the phase of the wind turbine with the control system to a stopped-icing phase, wherein rotation of the blades of the wind turbine is halted when the wind turbine is in the stopped-icing phase. |
| FILED | Tuesday, July 13, 2021 |
| APPL NO | 18/005549 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Wind Motors F03D 7/0224 (20130101) Original (OR) Class F03D 80/40 (20160501) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2270/328 (20130101) F05B 2270/335 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946871 | Shashurin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Alexey Shashurin (West Lafayette, Indiana); Xingxing Wang (West Lafayette, Indiana) |
| ABSTRACT | Methods and systems capable of measuring gas temperatures utilizing plasma discharges. Such a method performs a measurement of a temperature of a gas by generating a probing nanosecond plasma pulse in the gas, and then using an optical emission spectroscopy technique to measure the temperature of the gas by processing a light emission signal excited by the probing nanosecond plasma pulse. |
| FILED | Friday, October 30, 2020 |
| APPL NO | 17/085856 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/67 (20130101) Original (OR) Class G01N 21/1702 (20130101) G01N 2021/1704 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946895 | Shahrjerdi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Davood Shahrjerdi (New York, New York); Roozbeh Kiani (New York, New York); Ting Wu (New York, New York) |
| ABSTRACT | Principles for reliable manufacturing carbon-based electrodes with arbitrary sensitivity and homogeneity are provided. Specifically, the sensitivity of carbon-based electrodes can be engineered by changing the density of sp2 type defects present in a multilayer graphene film. The engineered carbon-based electrodes can be used as a passive sensing element in electrochemical measurement of a target analyte. Carbon-based electrodes are also disclosed that have sp2 hybridization and can include multilayer graphene films. The disclosed carbon-based electrodes have a density of zero-dimensional defects (i.e., point-like defects) which provides enhanced area-normalized sensitivity when used in sensing applications. The maximum area-normalized sensitivity is achieved at the point defect density of 4-5×1012 cm−2. |
| FILED | Tuesday, July 31, 2018 |
| APPL NO | 16/635634 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/308 (20130101) Original (OR) Class G01N 33/48707 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946896 | Arumugam |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Louisiana Tech Research Corporation (Ruston, Louisiana) |
| ASSIGNEE(S) | Louisiana Tech Research Corporation (Ruston, Louisiana) |
| INVENTOR(S) | Prabhu Arumugam (Ruston, Louisiana) |
| ABSTRACT | A GABA detecting probe having a probe body with both a glutamate (Glu) micro-sensor and a GABA micro-sensor positioned on the probe body. The Glu micro-sensor and the GABA micro-sensor include electrodes having a surface modification with (i) GOx and a binding matrix, and (ii) GABASE, GOx, and the binding matrix, respectively. The sensors are positioned no further apart than 250 um and includes a sentinel site located on the probe body. |
| FILED | Thursday, March 05, 2020 |
| APPL NO | 16/810459 |
| ART UNIT | 1759 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3275 (20130101) Original (OR) Class G01N 33/9426 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11947098 | Preza et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chrysanthe Preza (Memphis, Tennessee); Ana Doblas (Memphis, Tennessee); Genaro Saavedra-Tortosa (Valencia, Spain); Manuel Martinez-Corral (Valencia, Spain); Juan Carlos Barreiro (Valencia, Spain) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chrysanthe Preza (Memphis, Tennessee); Ana Doblas (Memphis, Tennessee); Genaro Saavedra-Tortosa (Valencia, Spain); Manuel Martinez-Corral (Valencia, Spain); Juan Carlos Barreiro (Valencia, Spain) |
| ABSTRACT | A multi-focal light-sheet structured illumination system that can be implemented as a part of a commercial fluorescence microscope or a module that is adaptable to fit a number of commercially available microscopes. The system provides simultaneous capture of 2D images from multiple planes within a 3D volume, which are resolved laterally and axially to provide improved resolution along the three dimensions (x,y,z). A Wollaston prism allows several axially-localized high-contrast structured illumination patterns to be generated. |
| FILED | Tuesday, March 29, 2022 |
| APPL NO | 17/707628 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/0032 (20130101) G02B 21/0064 (20130101) G02B 21/0076 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11947163 | Jia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| ASSIGNEE(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| INVENTOR(S) | Xiaoting Jia (Blacksburg, Virginia); Anbo Wang (Blacksburg, Virginia); Haifeng Xuan (Blacksburg, Virginia); Li Yu (Blacksburg, Virginia) |
| ABSTRACT | In one aspect, the disclosure relates to multi-material fibers capable of distributedly measuring temperature and pressure in which the methods comprise a thermal drawing step, and the methods of fabricating the disclosed fibers. The fibers can be utilized in methods of temperature and pressure mapping or sensing comprising electrical reflectometry for interrogation. Further disclosed are devices comprising a disclosed fiber with the multi-point detection capability with simple one-end connection. Also disclosed are articles, e.g., smart clothing, wound dressing, robotic skin and other industrial products, comprising a disclosed fiber or a fabric comprising a disclosed fiber. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Thursday, June 04, 2020 |
| APPL NO | 16/893281 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0023 (20130101) D01D 5/34 (20130101) D01D 5/084 (20130101) D01D 5/098 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/441 (20130101) Woven Fabrics; Methods of Weaving; Looms D03D 1/0088 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/00 (20130101) D06M 15/00 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2101/20 (20130101) D10B 2401/16 (20130101) D10B 2401/18 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/0002 (20130101) Optical Elements, Systems, or Apparatus G02B 6/10 (20130101) Original (OR) Class G02B 2006/12069 (20130101) G02B 2006/12111 (20130101) G02B 2006/12166 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/00 (20130101) H01B 3/02 (20130101) H01B 3/12 (20130101) H01B 3/30 (20130101) H01B 3/082 (20130101) H01B 7/04 (20130101) H01B 19/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11947622 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| INVENTOR(S) | Yi Xu (Endwell, New York); Zhongfei Mark Zhang (Vestal, New York) |
| ABSTRACT | The general problem of pattern change discovery between high-dimensional data sets is addressed by considering the notion of the principal angles between the subspaces is introduced to measure the subspace difference between two high-dimensional data sets. Current methods either mainly focus on magnitude change detection of low-dimensional data sets or are under supervised frameworks. Principal angles bear a property to isolate subspace change from the magnitude change. To address the challenge of directly computing the principal angles, matrix factorization is used to serve as a statistical framework and develop the principle of the dominant subspace mapping to transfer the principal angle based detection to a matrix factorization problem. Matrix factorization can be naturally embedded into the likelihood ratio test based on the linear models. The method may be unsupervised and addresses the statistical significance of the pattern changes between high-dimensional data sets. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/114484 |
| ART UNIT | 2146 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Original (OR) Class G06F 18/213 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11948302 | Grier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York); SPHERYX, INC. (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York); Spheryx, Inc (New York, New York) |
| INVENTOR(S) | David G. Grier (New York, New York); Fook Chiong Cheong (Brooklyn, New York); Kaitlynn Snyder (New York, New York); Rushna Quddus (New York, New York); Lauren E. Altman (New York, New York); Kent Kirshenbaum (New York, New York) |
| ABSTRACT | An in-line holographic microscope can be used to analyze a video stream to track individual colloidal particles' three-dimensional motions. The system and method can provide real time nanometer resolution, and simultaneously measure particle sizes and refractive indexes. An assay using the holographic microscope for holographic particle characterization directly detect viruses, antibodies and related targets binding to the surfaces of specifically functionalized micrometer-scale colloidal probe beads. The system detects binding of targets by directly measuring associated changes in the bead's diameter without the need for downstream labeling and analysis. |
| FILED | Tuesday, March 09, 2021 |
| APPL NO | 17/196895 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) G01N 2015/1445 (20130101) Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) Holographic Processes or Apparatus G03H 1/0005 (20130101) G03H 1/0465 (20130101) G03H 2001/005 (20130101) G03H 2001/0471 (20130101) G03H 2210/55 (20130101) G03H 2222/13 (20130101) G03H 2222/34 (20130101) Image Data Processing or Generation, in General G06T 7/0014 (20130101) Original (OR) Class G06T 7/62 (20170101) G06T 2207/10056 (20130101) G06T 2207/30024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11948311 | Cauley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Stephen Cauley (Somerville, Massachusetts); Melissa Haskell (Cambridge, Massachusetts); Lawrence Wald (Cambridge, Massachusetts) |
| ABSTRACT | A combined physics-based and machine learning framework is used for reconstructing images from k-space data, in which motion artifacts are significantly reduced in the reconstructed images. In general, model-based retrospective motion correction techniques are accelerated using fast machine learning (“ML”) steps, which may be implemented using a trained neural network such as a convolutional neural network. In this way, the confidence of a classical physics-based reconstruction is obtained with the computational benefits of an ML-based network. |
| FILED | Thursday, March 26, 2020 |
| APPL NO | 17/442962 |
| ART UNIT | 2672 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/4046 (20130101) G06T 7/251 (20170101) Original (OR) Class G06T 2207/10088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11949163 | Yoon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Yong Kyu Yoon (Gainesville, Florida); Renuka Bowrothu (Gainesville, Florida); Haein Kim (Gainesville, Florida); Seahee Hwangbo (Beaverton, Oregon) |
| ABSTRACT | The present disclosure describes various embodiments of systems, apparatuses, and methods for implementing an array antenna having a combination of ferromagnetic and nonferromagnetic conductors in alternating multilayers. One such antenna device comprises an array of patch antennas on a substrate, wherein the patch antennas are formed of a combination of ferromagnetic and nonferromagnetic conductors in alternating multilayers; and a microstrip feeding line coupled to the array of patch antennas. Other systems, apparatuses, and methods are also presented. |
| FILED | Wednesday, April 14, 2021 |
| APPL NO | 17/230347 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/422 (20130101) H01Q 9/0414 (20130101) H01Q 21/065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11950304 | Ganguly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Amlan Ganguly (West Henrietta, New York); Minseok Kwon (Pittsford, New York); Andres Kwasinski (Fairport, New York); Sayed Ashraf Mamun (Rochester, New York); Sree Gowrishankar Umamaheswaran (Mishawaka, Indiana) |
| ASSIGNEE(S) | Rochester Institute of Technology (Rochester, New York) |
| INVENTOR(S) | Amlan Ganguly (West Henrietta, New York); Minseok Kwon (Pittsford, New York); Andres Kwasinski (Fairport, New York); Sayed Ashraf Mamun (Rochester, New York); Sree Gowrishankar Umamaheswaran (Mishawaka, Indiana) |
| ABSTRACT | A wireless server-to-server datacenter network architecture uses wireless links to eliminate the need for power-hungry switching fabric of traditional fat-tree based datacenter networks. The server-to-server wireless datacenter network (S2S-WiDCN) requires Line-of-Sight (LoS) between servers to establish direct communication links. Utilizing this LoS links, a horizontal-first routing algorithm is developed which, will establish fast communication links between any pair of communicating servers in the data center. The wireless links can be realized in millimeter-wave (such as 30, 60, 120 GHz) or THz (such as 300 GHz) frequency bands. The use of antenna-arrays to create beam-steering towards communicating servers is necessary to establish the direct server-to-server links. In the presence of an obstruction such as an IT technician, the LoS between communicating servers may be blocked. To address this issue, an obstruction-aware adaptive routing algorithm for the S2S-WiDCN is proposed. Alternatively, the wireless links can be realized with FSO. The performance of such a wireless data center is better than that of conventional tree-based wired data centers while its power consumption is significantly lower than that of the conventional data center network. |
| FILED | Thursday, April 18, 2019 |
| APPL NO | 16/388007 |
| ART UNIT | 2468 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 10/114 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 49/40 (20130101) H04L 67/12 (20130101) Wireless Communication Networks H04W 4/33 (20180201) H04W 4/80 (20180201) H04W 16/28 (20130101) H04W 40/20 (20130101) H04W 40/248 (20130101) H04W 52/02 (20130101) H04W 76/14 (20180201) H04W 76/15 (20180201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11944090 | Chen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Jian Chen (Greenville, Mississippi) |
| ABSTRACT | Disclosed herein are compositions for attracting fire ants wherein the compositions contain at least one fire ant food source, and at least one of 10-oxo-dodecanoic acid, 11-oxo-dodecanoic acid, or a mixture thereof, and optionally a carrier. Disclosed are also methods for attracting fire ants, the methods involving treating an object or area with a fire ant-attracting effective amount of a composition of the invention. |
| FILED | Wednesday, August 03, 2022 |
| APPL NO | 17/879968 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944951 | Moore, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Philip A. Moore, Jr. (Fayetteville, Arkansas) |
| ABSTRACT | Calcium silicate hydrate nanoparticles are combined with ammonia control materials (e.g. alum, aluminum chloride, ferric chloride, ferric sulfate, and/or sodium bisulfate) to create a phosphorus-binding composition. In the preferred embodiment, the composition is applied to poultry litter, poultry bedding or other non-aqueous substrates that are at least partially comprised of animal manure. The composition binds with phosphorus to at least reduce the amount of phosphorus in runoff water or in leachate from fields fertilized with treated manure. The combining of the calcium silicate hydrate nanoparticles with the ammonia control products has a surprising and unexpected result. The calcium silicate hydrate-ammonia control material mix reduces soluble phosphorus more than either component of the mix alone. |
| FILED | Tuesday, February 09, 2021 |
| APPL NO | 17/171204 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/10 (20130101) B01J 20/045 (20130101) Original (OR) Class Disposal of Solid Waste B09B 3/25 (20220101) Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse C05F 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946058 | Hunter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); AUM LifeTech, Inc. (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); AUM LifeTech, Inc. (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Wayne B. Hunter (Port St Lucie, Florida); Veenu Aishwarya (Philadelphia, Pennsylvania) |
| ABSTRACT | Herein is disclosed synthetic oligonucleotides comprising 2′F-ANA nucleosides that can be utilized to control plant-chewing and phloem-feeding insects, bacteria present in such insects, and bacteria present in plants. The novel approaches and materials provided herein allow for reduction of pesticide and antibiotic use without the need to create genetically modified plants. |
| FILED | Wednesday, January 05, 2022 |
| APPL NO | 17/568884 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/8218 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/323 (20130101) C12N 2310/346 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946933 | Talaat |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Adel M. Talaat (Madison, Wisconsin) |
| ABSTRACT | Mycobacterial-specific biomarkers and methods of using such biomarkers for diagnosis of mycobacterial infection in a mammal are disclosed. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/170856 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5695 (20130101) Original (OR) Class G01N 33/56933 (20130101) G01N 2333/30 (20130101) G01N 2469/10 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11944426 | Pearlman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Jonathan L. Pearlman (Pittsburgh, Pennsylvania); Jonathan A. Duvall (Pittsburgh, Pennsylvania); Samuel T. Bucior (Greenboro, North Carolina) |
| ABSTRACT | A load cell apparatus includes a base member, a cap member, a number of first members provided between the base member and the cap member and forming at least a portion of a support wall of the load cell apparatus, and a plurality of strain gauges directly coupled to the number of first members, the plurality of strain gauges being positioned to measure an axial load applied to the load cell in a direction extending from the cap member to the base member. |
| FILED | Friday, January 11, 2019 |
| APPL NO | 16/959589 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1036 (20130101) Original (OR) Class A61B 5/6891 (20130101) A61B 5/6894 (20130101) A61B 2562/0252 (20130101) A61B 2562/0261 (20130101) Weighing G01G 3/14 (20130101) G01G 19/44 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/2231 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11944648 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seattle, Washington) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seattle, Washington) |
| INVENTOR(S) | Yvonne Y. Chen (Los Angeles, California); Eugenia Zah (Los Angeles, California); Michael C. Jensen (Seattle, Washington) |
| ABSTRACT | A CD19-OR-CD20 chimeric antigen receptor (CAR) protein construct is provided. Also provided are nucleic acids encoding the CD19-OR-CD20 CAR; and methods of use, e.g. in the treatment of B cell malignancies. The CD19-OR-CD20 CAR of the invention is a bispecific CAR that can trigger T-cell activation upon detection of either CD19 or CD20 (or both). It is a single molecule that confers two-input recognition capability upon human T cells engineered to stably express this CAR. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/238210 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70596 (20130101) C07K 16/46 (20130101) C07K 16/2803 (20130101) C07K 16/2887 (20130101) C07K 2317/31 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11945781 | Suto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Southern Research Institute (Birmingham, Alabama); UAB Research Foundation (Birmingham, Alabama); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Southern Research Institute (Birmingham, Alabama); UAB Research Foundation (Birmingham, Alabama); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Mark J. Suto (Homewood, Alabama); Bini Mathew (Hoover, Alabama); Anupam Agarwal (Mountain Brook, Alabama); Amie M. Traylor (Talladega, Alabama) |
| ABSTRACT | The present disclosure is concerned with thioquinolinone compounds for the treatment of disorders associated with heme oxygenase-1 (HO-1) signaling dysfunction such as, for example, kidney diseases (e.g., chronic kidney disease, acute kidney injury). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/183281 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 321/28 (20130101) Heterocyclic Compounds C07D 213/70 (20130101) C07D 215/36 (20130101) Original (OR) Class C07D 215/40 (20130101) C07D 215/48 (20130101) C07D 217/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11945855 — Recombinant polypeptides comprising modified MHC class II DRa1 domains and methods of use
| US 11945855 | Meza-Romero et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Roberto Meza-Romero (Beaverton, Oregon); Arthur A. Vandenbark (Portland, Oregon); Halina Offner (Portland, Oregon) |
| ABSTRACT | Recombinant polypeptides comprising a modified DRα1 domain are provided. In some embodiments, the polypeptides include the modified DRα1 domain, an antigenic peptide, and optionally a linker sequence. Pharmaceutical compositions comprising the recombinant polypeptides, methods of treating inflammatory disease using said recombinant polypeptides or pharmaceutical compositions, and expression constructs comprising nucleic acids that encode the recombinant polypeptides are also provided. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/282455 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0008 (20130101) A61K 2039/6031 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Peptides C07K 14/70539 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11945154 | de León |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pablo Gabriel de León (Cape Canaveral, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pablo Gabriel de León (Cape Canaveral, Florida) |
| ABSTRACT | The present disclosure relates to printing apparatus and manufacturing techniques for the manufacture and fabrication of pressure suits and space suits. The disclosure also relates to space suit components formed from additive polymer, and components including one or more layers of a mesh fabric with an applied layer of an additive polymer. One method includes providing an apparatus comprised of a six-degree of freedom motion manipulator with the motion manipulator attached to one or more printing extruder heads. Additive polymers may be extruded via the one or more printing extruder heads to form 3D printed space suit components. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/098008 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) Original (OR) Class B29C 64/209 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2029/00 (20130101) B29K 2031/04 (20130101) B29K 2055/02 (20130101) B29K 2067/046 (20130101) B29K 2075/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/768 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 70/00 (20141201) Cosmonautics; Vehicles or Equipment Therefor B64G 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946883 | Koshti |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Ajay M Koshti (League City, Texas) |
| ABSTRACT | A method includes determining a predicted contrast-to-noise ratio sensitivity function (CNR SF) for crack detection of a predetermined target flaw size with the radiographic inspection system in the selected set-up. The method also includes qualifying an inspection image quality indicator (IQI) for the predetermined target flaw size for use in the radiographic inspection system in the selected set-up. The method also includes performing an inspection process. The inspection process includes selecting the qualified inspection IQI for the predetermined target flaw size. The inspection process also includes performing an inspection test on the qualified inspection IQI using the radiographic inspection system in the selected set-up. The inspection process also includes determining one or more inspection output parameters. The inspection process also includes verifying that the one or more inspection output parameters meet or exceed minimum qualified values to qualify the radiographic inspection system in the selected set-up. |
| FILED | Monday, November 15, 2021 |
| APPL NO | 17/454865 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) G01N 23/18 (20130101) Original (OR) Class G01N 23/083 (20130101) G01N 2223/42 (20130101) G01N 2223/305 (20130101) G01N 2223/401 (20130101) G01N 2223/415 (20130101) G01N 2223/426 (20130101) G01N 2223/629 (20130101) G01N 2223/1016 (20130101) G01N 2223/3035 (20130101) G01N 2223/3037 (20130101) G01N 2223/6466 (20130101) Image Data Processing or Generation, in General G06T 7/0004 (20130101) G06T 2207/30136 (20130101) G06T 2207/30168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11948467 | Bateman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Barron Associates, Inc. (Charlottesville, Virginia) |
| ASSIGNEE(S) | Barron Associates, Inc. (Charlottesville, Virginia) |
| INVENTOR(S) | Alec Jacob Devine Bateman (Charlottesville, Virginia) |
| ABSTRACT | Embodiments of a system, device and method improve weather modeling approaches for use by air vehicles to mitigate weather hazards and/or optimize air vehicle operations. Various embodiments collect a set of independent measurements of atmospheric parameters of interest, collect a set of onboard measurements from one or more non-traditional atmospheric sensors onboard an air vehicle, process the collected measurements to identify values of selected atmospheric parameters and generate a model for relating raw sensor outputs from the non-traditional atmospheric sensors to the atmospheric parameters of interest. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/316914 |
| ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Unmanned aerial vehicles [UAV]; equipment therefor B64U 2101/35 (20230101) Traffic Control Systems G08G 5/0034 (20130101) G08G 5/0039 (20130101) G08G 5/0091 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11948709 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Universities Space Research Association (Columbia, Maryland) |
| ASSIGNEE(S) | Universities Space Research Association (Columbia, Maryland) |
| INVENTOR(S) | Jin-Woo Han (Mountain View, California); Meyya Meyyappan (San Jose, California); Dong-Il Moon (Mountain View, California) |
| ABSTRACT | An all-printed physically unclonable function based on a single-walled carbon nanotube network. The network may be a mixture of semiconducting and metallic nanotubes randomly tangled with each other through the printing process. The unique distribution of carbon nanotubes in a network can be used for authentication, and this feature can be a secret key for a high level hardware security. The carbon nanotube network does not require any advanced purification process, alignment of nanotubes, high-resolution lithography and patterning. Rather, the intrinsic randomness of carbon nanotubes is leveraged to provide the unclonable aspect. |
| FILED | Tuesday, February 08, 2022 |
| APPL NO | 17/666716 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Resistors H01C 1/14 (20130101) H01C 1/034 (20130101) H01C 7/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11949595 | Levitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Yonatan Meir Levitt (Brookline, Massachusetts); Gaspar Mora Porta (Campbell, California) |
| ABSTRACT | An apparatus includes a first set of processing element nodes, the first set of processing element nodes defining a first hierarchy of processing element nodes, the first set of processing element nodes comprising a source node, a first look-up table (LUT), and a first forwarder node, the source node to communicate with the first forwarder node by a first virtual channel. The apparatus includes a second set of processing element nodes, the second set of processing element nodes defining a second hierarchy of processing element nodes, the second set of processing element nodes comprising a second forwarder node, a second LUT, the second LUT comprising an indication of a direction of the first forwarder node in the first hierarchy, and a target node logically coupled to the second forwarder node by the first virtual channel. The first LUT comprises a direction of the second forwarder node in the second hierarchy. |
| FILED | Friday, June 26, 2020 |
| APPL NO | 16/913433 |
| ART UNIT | 2413 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 12/4675 (20130101) H04L 45/34 (20130101) H04L 45/742 (20130101) H04L 45/7453 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11946383 | Davis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RTX Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Todd A. Davis (Tolland, Connecticut); Christopher M. Valva (Manchester, Connecticut) |
| ABSTRACT | A gas turbine engine includes a first bearing compartment and a seal assembly within the first bearing compartment that includes a rotatable seal seat, a gutter radially outward of the seal seat and fixed against rotation. The gutter includes a channel on its radially inner face. A second bearing compartment is also included. A scavenge pump is in communication with a first supply line configured to supply the first bearing compartment and a second supply line configured to supply the second bearing compartment. The gutter is in communication with the scavenge pump through a gutter scavenge line. |
| FILED | Tuesday, June 28, 2022 |
| APPL NO | 17/851412 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/20 (20130101) F01D 25/186 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/98 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 33/76 (20130101) F16C 33/6637 (20130101) F16C 2360/23 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11946391 | Gunasekera et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Anthony Michael Gunasekera (New Richmond, Ohio); Nicholas Joseph Kray (Mason, Ohio); Leslie Louis Langenbrunner (Cincinnati, Ohio); Simeon Paul Copple (Wilmington, Ohio) |
| ABSTRACT | A composite airfoil having a non-metallic leading edge protective wrap is provided. In one aspect, the airfoil has a composite core having a pressure sidewall and a suction sidewall each extending between a core leading edge and a core trailing edge. A leading edge protective wrap protects the core leading edge and includes a trailing wrap and a leading wrap. The trailing wrap wraps around the core leading edge and is connected to the composite core. The leading wrap wraps around the core leading edge and is connected to the trailing wrap. The trailing and leading wraps both have leading edges that are spaced from one another. A filler is positioned between the leading edges of the trailing and leading wraps. A protective nose is connected to the leading edge of the leading wrap. The components of the leading edge protective wrap are formed of non-metallic materials. |
| FILED | Thursday, March 11, 2021 |
| APPL NO | 17/198843 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 11/26 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/282 (20130101) F01D 9/041 (20130101) Original (OR) Class F01D 25/005 (20130101) Non-positive-displacement Pumps F04D 29/388 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/12 (20130101) F05D 2240/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11947055 | Miao |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Houxun Miao (Zionsville, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Houxun Miao (Zionsville, Indiana) |
| ABSTRACT | Disclosed herein is a pixelated x-ray scintillator with a multilayer reflector for x-ray detectors with simultaneous high spatial resolution and high quantum efficiency and fabrication method to produce the pixelated x-ray scintillator. The multilayer reflector provides high reflectivity for the emitted visible photons over a broad incident angle range, thus boosts the light output efficiency of the pixelated x-ray scintillator. The fabrication process to produce the pixelated scintillator with the multilayer reflector in this disclosure is compatible with standard semiconductor fabrication instrument and suitable for mass production. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 17/744841 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/242 (20130101) G01T 1/2002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11949224 | Hsia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy T. Hsia (Irvine, California); Victor K. Lee (Irvine, California) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Timothy T. Hsia (Irvine, California); Victor K. Lee (Irvine, California) |
| ABSTRACT | One example includes a power supply system. The system includes a voltage-limit power regulator to generate an output voltage and an instantaneous overvoltage sensor configured to detect an overvoltage condition associated with the output voltage. The system further includes an overvoltage latch-off timer system configured to initiate a latch-off timer in response to detecting the overvoltage condition. The latch-off timer can be uninterrupted by an amplitude of the output voltage. The overvoltage latch-off timer system can further be configured to detect a persistent overvoltage fault in response to detecting the overvoltage condition after expiration of the latch-off timer. The overvoltage latch-off timer system can be configured to generate a fault signal to disable the voltage-limit power regulator in response to detecting the persistent overvoltage fault. |
| FILED | Friday, March 25, 2022 |
| APPL NO | 17/704089 |
| ART UNIT | 2839 — Semiconductors/Memory |
| CURRENT CPC | Emergency Protective Circuit Arrangements H02H 1/0007 (20130101) H02H 3/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11949540 | Agee |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian G. Agee (San Jose, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian G. Agee (San Jose, California) |
| ABSTRACT | An apparatus and digital signal processing means are disclosed for excision of co-channel interference from signals received in crowded or hostile environments using spatial/polarization diverse arrays, which reliably and rapidly identifies communication signals with transmitted features that are self-coherent over known framing intervals due to known attributes of the communication network, and exploits those features to develop diversity combining weights that substantively excise that co-channel interference from those communication signals, based on differing diversity signature, timing offset, and carrier offset between the network signals and the co-channel interferers. In one embodiment, the co-channel interference excision is performed in an appliqué that can be implemented without coordination with a network transceiver. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/803636 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 7/0617 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/08 (20130101) Original (OR) Class H04L 27/264 (20130101) H04L 27/26414 (20210101) H04L 27/26538 (20210101) Wireless Communication Networks H04W 28/14 (20130101) H04W 52/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, April 02, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
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THE PANEL
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FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
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FILED
The date of the patent application including the day of the week.
APPL NO
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ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240402.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page