FedInvent™ Patents

Patent Details for Tuesday, April 23, 2024 

This page was updated on Saturday, June 08, 2024 at 03:49 PM GMT

Department of Health and Human Services (HHS) 

US 11963750 Castro-Gonzalez et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Universidad Politecnica De Madrid (Madrid, Spain)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Universidad Politecnica De Madrid (Madrid, Spain)
INVENTOR(S) Carlos Castro-Gonzalez (Cambridge, Massachusetts);  Ian Butterworth (Somerville, Massachusetts);  Aurelien Bourquard (Madrid, Spain);  Alvaro Sanchez Ferro (Madrid, Spain);  Jason Tucker-Schwartz (Melrose, Massachusetts);  Alberto Pablo Trinidad (Madrid, Spain);  Maria J. Ledesma Carbayo (Madrid, Spain);  Tom Vettenburg (Dundee, United Kingdom)
ABSTRACT A system for non-invasive hematological measurements includes a platform to receive a body portion of a user and an imaging device to acquire a set of images of a capillary bed in the body portion. For each image, a controller detects one or more capillaries in the body portion of the finger to identify a first set of capillaries by estimating one or more attributes of each capillary (e.g., structural attributes, flow attributes, imaging attributes, or combinations thereof), wherein at least one attribute of each capillary meets a predetermined criterion. The controller also identifies a second set of capillaries from the first set of capillaries such that each capillary of the second set of capillaries is visible in a predetermined number of images of the set of images.
FILED Monday, February 07, 2022
APPL NO 17/666461
ART UNIT 2672 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0261 (20130101) Original (OR) Class
A61B 5/489 (20130101)
A61B 5/1455 (20130101)
A61B 5/6826 (20130101)
A61B 5/7203 (20130101)
A61B 5/7267 (20130101)
A61B 5/14546 (20130101)
A61B 2576/02 (20130101)

Image Data Processing or Generation, in General
G06T 7/0014 (20130101)
G06T 2207/10016 (20130101)
G06T 2207/10152 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30101 (20130101)

Image or Video Recognition or Understanding
G06V 40/10 (20220101)
G06V 40/14 (20220101)
G06V 40/15 (20220101)

Technologies for Adaptation to Climate Change
Y02A 90/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963785 Franz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina)
INVENTOR(S) Jason Roy Franz (Durham, North Carolina);  Mu Qiao (Ruston, Louisiana)
ABSTRACT Methods, systems, and computer readable media for utilizing visuomotor error augmentation for balance rehabilitation are provided. An exemplary method includes displaying a dynamic virtual environment defined by an optical flow, obtaining position data of an anatomical portion of a subject that is virtually traversing the dynamic virtual environment, and using the position data to determine a mediolateral displacement measurement of the subject. The method further includes utilizing the mediolateral displacement measurement to define feedback control loop data, establishing an augmented visual error that dynamically adjusts the dynamic virtual environment, wherein the augmented visual error is based on the feedback control loop data and a predefined visual gain factor, and adjusting the optical flow of the dynamic virtual environment by using the augmented visual error.
FILED Tuesday, March 16, 2021
APPL NO 17/202989
ART UNIT 2699 — Search and Capture Special Detail
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/112 (20130101)
A61B 5/4023 (20130101) Original (OR) Class
A61B 2505/09 (20130101)

Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 26/003 (20130101)
A63B 71/0622 (20130101)
A63B 2071/0638 (20130101)
A63B 2071/0644 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963787 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Zhongming Li (Cambridge, Massachusetts);  Angela Belcher (Lexington, Massachusetts)
ABSTRACT This disclosure provides a method for imaging lymph nodes and lymphatic vessels without a contrast agent. The method includes providing, using an optical source, an infrared illumination to a region of a subject having at least one lymphatic component, detecting a reflected portion of the infrared illumination directly reflected from the region using a sensor positioned thereabout, and generating at least one image indicative of the at least one lymphatic component in the subject using the reflected portion of the infrared illumination.
FILED Thursday, January 12, 2023
APPL NO 18/096461
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0062 (20130101)
A61B 5/0082 (20130101)
A61B 5/418 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/21 (20130101)
G01N 21/35 (20130101)
G01N 2021/3137 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/30004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963789 Lang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Scott Buckley (Portland, Oregon);  Neil R. M. Buist (Portland, Oregon);  W. Christopher Lang (New Albany, Indiana)
ASSIGNEE(S) THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana)
INVENTOR(S) W. Christopher Lang (New Albany, Indiana);  Scott Buckley (Portland, Oregon);  Neil Buist (Portland, Oregon)
ABSTRACT A feeding analysis system reviews collected feeding data and provides analysis of data regarding nutritive sucking, feeding, and related activity.
FILED Thursday, March 22, 2018
APPL NO 15/933356
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/4542 (20130101) Original (OR) Class
A61B 5/7242 (20130101)
A61B 5/7246 (20130101)
A61B 5/7257 (20130101)
A61B 5/7267 (20130101)
A61B 5/7282 (20130101)
A61B 2503/045 (20130101)
A61B 2562/0247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963821 Yarmush et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S) Martin L. Yarmush (New Brunswick, New Jersey);  Alvin Chen (New Brunswick, New Jersey);  Max Balter (New Brunswick, New Jersey);  Joshua Leipheimer (New Brunswick, New Jersey)
ABSTRACT A device and method for directing a cannula toward a target location under a patient's skin. The device is handheld and the device operations may be automated. The device includes an imaging probe for imaging the target location, a positioning unit for manipulating a cannula towards the target location, and a processor. The processor receives imaging data from the imaging probe, cannula pose data from at least one cannula position sensor, and device pose data from at least one device position sensor. The target location is identified from the imaging data, and a trajectory for manipulating the cannula towards the target location is determined based on the imaging data, the cannula pose data, and the device pose data. The processor may determine that the trajectory becomes misaligned with the target position, and may update to a corrected trajectory based on the imaging data, cannula pose data, and the device pose data.
FILED Wednesday, October 09, 2019
APPL NO 17/284018
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/06 (20130101)
A61B 8/12 (20130101)
A61B 8/466 (20130101)
A61B 8/0841 (20130101) Original (OR) Class
A61B 8/4218 (20130101)
A61B 2034/2065 (20160201)
A61B 2562/0219 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963832 Xia et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) THE METHODIST HOSPITAL (Houston, Texas)
ASSIGNEE(S) The Methodist Hospital (Houston, Texas)
INVENTOR(S) James Jiong Xia (Houston, Texas);  Jaime Gateno (Bellaire, Texas);  Peng Yuan (Houston, Texas)
ABSTRACT Systems and methods for orthognathic surgical planning are described herein. An example computer-implemented method can include generating a composite three-dimensional (3D) model of a subject's skull, defining a primal reference frame for the composite 3D model, performing a cephalometric analysis on the composite 3D model to quantify at least one geometric property of the subject's skull, performing a virtual osteotomy to separate the composite 3D model into a plurality of segments, performing a surgical simulation using the osteotomized segments, and designing a surgical splint or template for the subject.
FILED Monday, December 12, 2022
APPL NO 18/079277
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/10 (20160201)
A61B 34/20 (20160201)
A61B 2034/102 (20160201)
A61B 2034/105 (20160201)
A61B 2034/107 (20160201)
A61B 2034/2068 (20160201)

Dentistry; Apparatus or Methods for Oral or Dental Hygiene
A61C 13/0004 (20130101) Original (OR) Class
A61C 13/0019 (20130101)

Image Data Processing or Generation, in General
G06T 7/0014 (20130101)
G06T 2207/30036 (20130101)
G06T 2207/30204 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963939 Ratan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Neuronasal, Inc. (Wexford, Pennsylvania);  Burke Neurological Institute (White Plains, New York)
ASSIGNEE(S) Neuronasal, Inc. (Wexford, Pennsylvania);  Burke Neurological Institute (White Plains, New York)
INVENTOR(S) Rajiv R. Ratan (Scarsdale, New York);  Saravanan Karuppagounder (White Plains, New York);  Thomas I. Bradshaw (Wynnewood, Pennsylvania)
ABSTRACT The present disclosure describes methods of treating a central nervous system condition associated with oxidative stress using a 5-lipoxigenase activating protein (FLAP) inhibitor, for example, N-acetylcysteine or nordihydroguaiaretic acid. The present disclosure also describes methods of treating a central nervous system condition with N-acetylcysteine and a second therapeutic agent such as prostaglandin E2.
FILED Friday, January 13, 2023
APPL NO 18/154550
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0043 (20130101)
A61K 31/05 (20130101)
A61K 31/145 (20130101)
A61K 31/198 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/18 (20180101)
A61P 25/24 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963945 Boger et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland);  Board of Regents of the University of Nebraska (Omaha, Nebraska)
ASSIGNEE(S) THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland);  BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Omaha, Nebraska)
INVENTOR(S) Ravit Boger (Baltimore, Maryland);  Jonathan Vennerstrom (Omaha, Nebraska)
ABSTRACT Described are methods of treating or preventing a virus in a subject comprising administering ozonides to the subject.
FILED Thursday, January 06, 2022
APPL NO 17/570376
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/357 (20130101) Original (OR) Class
A61K 31/4525 (20130101)
A61K 31/5377 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/22 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963949 Prossnitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico)
ASSIGNEE(S) UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico)
INVENTOR(S) Eric R. Prossnitz (Albuquerque, New Mexico);  Geetanjali Sharma (Albuquerque, New Mexico);  Matthias Barton (Zurich, Switzerland);  Matthias R. Meyer (Stallikon, Switzerland)
ABSTRACT The current invention is in the field of molecular biology/pharmacology and provides methods of using compounds that modulate the effects of GPR30/GPER for treating obesity and diabetes (preferably agonists) as well as disease states and/or conditions that result from excessive formation of reactive oxygen species (preferably antagonists). These compounds may function as agonists and/or antagonists of the disclosed estrogen receptor and/or modulate the expression/upregulation of nox and nox-associated reactive oxygen species (ROS).
FILED Monday, March 01, 2021
APPL NO 17/188384
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/16 (20130101)
A61K 31/435 (20130101)
A61K 31/436 (20130101) Original (OR) Class
A61K 31/437 (20130101)
A61K 31/4355 (20130101)
A61K 31/7088 (20130101)
A61K 38/28 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2800/042 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963954 Min et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York);  ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tennessee)
ASSIGNEE(S) Memorial Sloan Kettering Cancer Center (New York, New York);  St. Jude Children's Research Hospital (Memphis, Tennessee)
INVENTOR(S) Jaeki Min (Memphis, Tennessee);  Daniel C. Scott (Marion, Arkansas);  Deepak Bhasin (Cordova, Tennessee);  Brenda A. Schulman (Memphis, Tennessee);  Bhuvanesh Singh (Old Westbury, New York);  Jared T. Hammill (Memphis, Tennessee);  R. Kiplin Guy (Memphis, Tennessee)
ABSTRACT In one aspect, the invention relates to substituted 1-phenyl-3-(piperidin-4-yl)urea analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the DCN1-UBC12 interaction inhibitors of DCN1-mediated cullin-RING ligase activity, methods of making same, pharmaceutical compositions comprising same, methods of treating disorders using the disclosed compounds and compositions, methods of treating disorders associated with a DCN1-UBC12 interaction dysfunction, methods of treating disorders associated with a DCN1-mediated cullin-RING ligase activity dysfunction, methods of male contraception comprising the disclosed compounds and compositions, and kits comprising the disclosed compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Thursday, September 09, 2021
APPL NO 17/470678
ART UNIT 1699 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/17 (20130101)
A61K 31/437 (20130101)
A61K 31/451 (20130101)
A61K 31/454 (20130101)
A61K 31/506 (20130101)
A61K 31/4525 (20130101)
A61K 31/4545 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 15/16 (20180101)
A61P 31/04 (20180101)
A61P 31/12 (20180101)

Heterocyclic Compounds
C07D 211/58 (20130101)
C07D 401/04 (20130101)
C07D 401/06 (20130101)
C07D 401/12 (20130101)
C07D 405/06 (20130101)
C07D 405/12 (20130101)
C07D 409/14 (20130101)
C07D 417/04 (20130101)
C07D 417/06 (20130101)
C07D 471/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963955 Olaleye
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
APPLICANT(S) Texas Southern University (Houston, Texas)
ASSIGNEE(S) Texas Southern University (Houston, Texas)
INVENTOR(S) Omonike A. Olaleye (Houston, Texas)
ABSTRACT Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), the etiological agent for coronavirus disease 2019 (COVID-19), has emerged as an ongoing global pandemic. Presently, there are no clinically approved vaccines nor drugs for COVID-19. Hence, there is an urgent need to accelerate the development of effective antivirals. One or more members of the 8-Hydroxyquinoline and Benzylamine structural classes inhibited SARS-CoV-2 infection induced cytopathic effect in vitro, inhibited the exopeptidase activity of angiotensin converting enzyme 2 (ACE2), and disrupted the binding between ACE2 and the Spike protein of SARS-CoV-2. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
FILED Friday, August 13, 2021
APPL NO 17/402419
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101) Original (OR) Class
A61K 31/137 (20130101)
A61K 33/30 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963957 Laberge et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Buck Institute for Research on Aging (Novato, California);  Unity Biotechnology, Inc. (South San Francisco, California);  Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota);  Unity Biotechnology, Inc. (Brisbane, California);  Buck Institute for Research on Aging (Novato, California)
INVENTOR(S) Remi-Martin Laberge (San Francisco, California);  Judith Campisi (Berkeley, California);  Albert Davalos (San Rafael, California);  Marco Demaria (Groningen, Netherlands);  Nathaniel David (Brisbane, California);  Jan M. A. van Deursen (Rochester, Minnesota);  Darren J. Baker (Rochester, Minnesota);  Bennett G. Childs (Rochester, Minnesota)
ABSTRACT Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders.
FILED Monday, December 07, 2020
APPL NO 17/114376
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0048 (20130101)
A61K 9/0073 (20130101)
A61K 31/404 (20130101)
A61K 31/428 (20130101)
A61K 31/495 (20130101)
A61K 31/496 (20130101) Original (OR) Class
A61K 31/728 (20130101)
A61K 31/4178 (20130101)
A61K 31/4375 (20130101)
A61K 31/5377 (20130101)
A61K 45/06 (20130101)
A61K 47/36 (20130101)
A61K 47/6807 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)
A61P 11/00 (20180101)
A61P 25/28 (20180101)
A61P 27/02 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0081 (20130101)
C12N 15/113 (20130101)
C12N 2320/30 (20130101)
C12N 2501/999 (20130101)
C12N 2503/02 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/485 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963964 Rubin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Lee L. Rubin (Wellesley, Massachusetts);  Amy J. Wagers (Cambridge, Massachusetts);  Amanda K. W. Gee (Alexandria, Virginia);  Feodor D. Price (Somerville, Massachusetts)
ABSTRACT The invention provides methods for inducing, enhancing or increasing satellite cell proliferation, and an assay for screening for a candidate compound for inducing, enhancing or increasing satellite cell proliferation. Also provided are methods for repairing or regenerating a damaged muscle tissue of a subject.
FILED Monday, June 07, 2021
APPL NO 17/341343
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/403 (20130101)
A61K 31/496 (20130101)
A61K 31/553 (20130101) Original (OR) Class
A61K 31/4439 (20130101)
A61K 31/5377 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 21/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963968 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
ASSIGNEE(S) Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
INVENTOR(S) Zheng-Yi Chen (Somerville, Massachusetts);  Wenyan Li (Boston, Massachusetts);  Yi-Zhou Quan (Dorchester, Massachusetts)
ABSTRACT Compositions for regeneration of inner cells and for treating hearing loss comprise at least one modulator of mechanistic target of rapamycin (mTOR) sufficient to induce reprogramming proliferation and regeneration of inner ear cells. The composition include, in some instances, an effective amount of one or more phosphatase and tensin homolog (PTEN) inhibitors, MYC/NOTCH modulators, Atonal Homolog 1 (Atoh1) modulators or combinations thereof.
FILED Friday, January 13, 2023
APPL NO 18/154474
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/19 (20130101)
A61K 31/365 (20130101)
A61K 31/7028 (20130101) Original (OR) Class
A61K 45/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963972 Schinazi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Emory University (Atlanta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Raymond F. Schinazi (Atlanta, Georgia);  Franck Amblard (Atlanta, Georgia);  Bryan D. Cox (Suwanee, Georgia);  Leda Bassit (Smyrna, Georgia);  Longhu Zhou (Atlanta, Georgia);  Christina Gavegnano (Atlanta, Georgia)
ABSTRACT The present invention is directed to compounds, compositions and methods for treating or preventing Zika virus. The compounds include pyrimidine and purine nucleosides and prodrugs thereof, including certain N4-hydroxycytidine nucleoside derivatives, sulfasalazine, and various entry inhibitors.
FILED Wednesday, March 22, 2017
APPL NO 16/088017
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/53 (20130101)
A61K 31/655 (20130101)
A61K 31/4706 (20130101)
A61K 31/7064 (20130101)
A61K 31/7068 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963975 Jones et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Peter L. Jones (Worcester, Massachusetts);  Michael R. Green (Worcester, Massachusetts)
ABSTRACT The disclosure relates to methods and compositions for regulating expression of DUX4. In some aspects, methods described by the disclosure are useful for treating a disease associated with aberrant DUX4 expression (e.g., facioscapulohumeral muscular dystrophy).
FILED Thursday, September 30, 2021
APPL NO 17/489983
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 31/5513 (20130101)
A61K 31/7105 (20130101) Original (OR) Class
A61K 45/06 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/90 (20130101)
C12N 15/113 (20130101)
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)
C12N 2310/20 (20170501)
C12N 2740/16043 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5061 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963980 Paulos et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) MUSC FOUNDATION FOR RESEARCH DEVELOPMENT (Charleston, South Carolina)
ASSIGNEE(S) MUSC Foundation for Research Development (Charleston, South Carolina)
INVENTOR(S) Chrystal M. Paulos (Charleston, South Carolina);  Michelle H. Nelson (Charleston, South Carolina);  Stefanie R. Bailey (Charleston, South Carolina)
ABSTRACT Provided herein are methods for the production of activated CD26high T cells by co-stimulation with inducible coactivator (ICOS). Further provided are methods for treatment of cancer by administration of the of activated CD26high T cells as an adoptive T cell therapy.
FILED Tuesday, April 25, 2017
APPL NO 16/095828
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101) Original (OR) Class
A61K 38/19 (20130101)
A61K 39/0011 (20130101)
A61K 39/001156 (20180801)
A61K 39/001168 (20180801)
A61K 2039/5156 (20130101)
A61K 2039/5158 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/163 (20130101)
C12N 5/0636 (20130101)
C12N 2510/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2800/52 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963983 Chaudhry
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Icahn School of Medicine at Mount Sinai (New York, New York)
ASSIGNEE(S) Icahn School of Medicine at Mount Sinai (New York, New York)
INVENTOR(S) Hina W. Chaudhry (New York, New York)
ABSTRACT Provided herein is a new method to isolate and expand cardiac progenitor/stem cells from a placenta, which produces a cell population enriched in multipotent functional progenitor/stem cells. Cardiac progenitor/stem cells isolated by this method maintain their self-renewal character in vitro and differentiate into normal cells in myocardium, including cardiomyocytes, endothelial cells, and smooth muscle cells, after transplantation into ischemic hearts. Also provided in this application are substantially pure populations of multipotent cardiac progenitor/stem cells, and their use to treat and prevent diseases and injuries, including those resulting from myocardial infarction. A model for assessing the potential of cardiac stem cells for treatment of myocardial infarction is also provided.
FILED Monday, November 25, 2019
APPL NO 16/693998
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/12 (20130101)
A61K 35/50 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964000 Stupp et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Samuel I. Stupp (Chicago, Illinois);  Mark Trosper McClendon (Chicago, Illinois);  Guifa Xi (Chicago, Illinois);  Bo Timmy Bjoern Fyrner (Kopparberg, Sweden);  Cara S. Smith (Chicago, Illinois);  Nicholas A. Sather (Evanston, Illinois)
ABSTRACT Provided herein are compositions comprising peptide amphiphiles, glycosylated peptide amphiphiles (GPAs), supramolecular nanostructures assembled therefrom, and methods of use thereof. The peptide amphiphiles described herein may extend the half-life of bone morphogenic proteins, promote cell differentiation, suppress proliferation, and increase chemosensitivity of cells. Accordingly, the compositions described herein may be used for cancer treatment methods. In particular, provided herein are bone morphogenic proteins bound to peptide amphiphiles and glycosylated peptide amphiphiles or composites thereof, and methods of use of the same for the treatment of cancer. Also, provided herein are bone morphogenic proteins bound to peptide amphiphiles and glycosylated peptide amphiphiles or composites thereof, and methods of use of the same in a combinatorial approach together with chemotherapeutic medications for the treatment of cancer.
FILED Monday, April 12, 2021
APPL NO 17/227943
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1875 (20130101) Original (OR) Class
A61K 45/06 (20130101)
A61K 47/61 (20170801)
A61K 47/549 (20170801)
A61K 47/641 (20170801)
A61K 47/645 (20170801)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964001 Morley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Sharon Celeste Morley (St. Louis, Missouri);  Elizabeth M. Todd (St. Louis, Missouri)
ASSIGNEE(S) Washington University (St. Louis, Missouri)
INVENTOR(S) Sharon Celeste Morley (St. Louis, Missouri);  Elizabeth M. Todd (St. Louis, Missouri)
ABSTRACT The present invention provides compositions and method for treating a subject having or suspected of having pulmonary dysfunction resulting from impaired alveolar macrophage (AM) development. The compositions comprise granulocyte-macrophage colony stimulating factor (GM-CSF) in formulations suitable for pulmonary airway administration.
FILED Thursday, April 09, 2020
APPL NO 16/844690
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/193 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 11/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964006 Ogembo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) CITY OF HOPE (Duarte, California)
ASSIGNEE(S) CITY OF HOPE (Duarte, California)
INVENTOR(S) Javier Gordon Ogembo (San Dimas, California);  Lorraine Zvichapera Mutsvunguma (Duarte, California);  Felix Wussow (Duarte, California)
ABSTRACT Disclosed are vaccine compositions comprising a VLP comprising two or more EBV envelope glycoproteins and one or more T cell antigens and methods of preventing or treating EBV infections using the vaccine compositions. Also disclosed is an expression system or a single expression vector for co-expressing two or more EBV envelope glycoproteins simultaneously to generate a VLP vaccine. The expression system may include a single vector inserted with two or more nucleic acid sequences that encode two or more EBV envelope glycoproteins linked by one or more linking sequences such that the EBV envelope glycoproteins are co-expressed simultaneously.
FILED Sunday, September 16, 2018
APPL NO 16/647705
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101) Original (OR) Class
A61K 2039/55505 (20130101)
A61K 2039/55572 (20130101)

Peptides
C07K 16/085 (20130101)
C07K 2317/76 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2710/16222 (20130101)
C12N 2710/16223 (20130101)
C12N 2710/16234 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964008 Livengood et al.
FUNDED BY
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S) TAKEDA VACCINES, INC. (Cambridge, Massachusetts)
ASSIGNEE(S) Takeda Vaccines, Inc. (Cambridge, Massachusetts)
INVENTOR(S) Jill A. Livengood (Cambridge, Massachusetts);  Holli Giebler (Cambridge, Massachusetts);  Hansi Dean (Cambridge, Massachusetts);  Tatsuki Satou (Hakari, Japan);  Raman Rao (Singapore, Singapore);  Jackie Marks (Cambridge, Massachusetts);  Mark Lyons (Cambridge, Massachusetts);  Asae Shintani (Hakari, Japan);  James Gifford (Cambridge, Massachusetts);  Sushma Kommareddy (Cambridge, Massachusetts)
ABSTRACT The present disclosure relates to methods for inactivating a Zika virus which can be used in vaccines and immunogenic compositions. The present disclosure also relates to a method for determining the completeness of inactivation of an arbovirus preparation.
FILED Tuesday, September 13, 2022
APPL NO 17/931887
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 39/12 (20130101) Original (OR) Class
A61K 39/39 (20130101)
A61K 2039/54 (20130101)
A61K 2039/545 (20130101)
A61K 2039/5252 (20130101)
A61K 2039/55505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/24034 (20130101)
C12N 2770/24071 (20130101)
C12N 2770/24134 (20130101)
C12N 2770/24151 (20130101)
C12N 2770/24163 (20130101)
C12N 2770/24164 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964010 Graham et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  The Scripps Research Institute (La Jolla, California);  Trustees of Dartmouth College (Hanover, New Hampshire)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland);  The Scripps Research Institute (La Jolla, California);  Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) Barney Graham (Rockville, Maryland);  Jason Mclellan (Austin, Texas);  Andrew Ward (La Jolla, California);  Robert Kirchdoerfer (La Jolla, California);  Christopher Cottrell (La Jolla, California);  Michael Gordon Joyce (Washington, District of Columbia);  Masaru Kanekiyo (Chevy Chase, Maryland);  Nianshuang Wang (Austin, Texas);  Jesper Pallesen (La Jolla, California);  Hadi Yassine (Doha, Qatar);  Hannah Turner (La Jolla, California);  Kizzmekia Corbett (Wheaton, Maryland)
ABSTRACT Coronavirus S ectodomain trimers stabilized in a prefusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the coronavirus S ectodomain trimers and/or nucleic acid molecules can be used to generate an immune response to coronavirus in a subject. In additional embodiments, the therapeutically effective amount of the coronavirus S ectodomain trimers and/or nucleic acid molecules can be administered to a subject in a method of treating or preventing coronavirus infection.
FILED Monday, March 08, 2021
APPL NO 17/194834
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/215 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2770/20022 (20130101)
C12N 2770/20034 (20130101)
C12N 2770/20071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964014 Bazin-Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE UNIVERSITY OF MONTANA (Missoula, Montana)
ASSIGNEE(S) THE UNIVERSITY OF MONTANA (Missoula, Montana)
INVENTOR(S) Helene Bazin-Lee (Stevensville, Montana);  David Burkhart (Missoula, Montana);  Jay Evans (Corvallis, Montana)
ABSTRACT Lipidated oxoadenines of formula (I) are TLR7/8 receptor ligands useful for modulating immune responses. The compounds may have therapeutic application in the treatment of cancer, infectious diseases, allergy, or autoimmune disorders.
FILED Tuesday, August 08, 2023
APPL NO 18/446041
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/39 (20130101) Original (OR) Class
A61K 2039/55505 (20130101)
A61K 2039/55511 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/65616 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964022 Koehler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Universität Zürich (Zürich, Switzerland)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts);  Universität Zürich (Zürich, Switzerland)
INVENTOR(S) Angela Nicole Koehler (Belmont, Massachusetts);  Shelby Doyle (Cambridge, Massachusetts);  Becky Leifer (Malden, Massachusetts);  Madeleine Henley (Brighton, Massachusetts);  Beat W. Schaefer (Zürich, Switzerland);  Marco Wachtel (Zürich, Switzerland)
ABSTRACT The present disclosure provides compounds having the general formula P-L-U, or pharmaceutically acceptable salts thereof, wherein P is a FOXO1 fusion protein binding moiety, L is a bivalent linker, and U is an ubiquitin ligase binding moiety. Also provided are pharmaceutical compositions containing such compounds and methods of using such compounds.
FILED Friday, September 16, 2022
APPL NO 17/946898
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/55 (20170801) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964028 Guo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
ASSIGNEE(S) UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (Lexington, Kentucky)
INVENTOR(S) Peixuan Guo (Columbus, Ohio);  Hui Li (Columbus, Ohio);  Wei Luo (Lexington, Kentucky)
ABSTRACT The presently-disclosed subject matter relates to an artificial RNA nanostructure and method of use thereof. In particular, the presently-disclosed subject matter relates to RNA nanoparticles and RNA dendrimers, and methods of disease diagnosis and treatments using the RNA nanostructure and RNA dendrimers.
FILED Monday, November 09, 2020
APPL NO 17/093038
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 51/12 (20130101)
A61K 51/0491 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 15/115 (20130101)
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)
C12N 2310/16 (20130101)
C12N 2310/52 (20130101)
C12N 2310/113 (20130101)
C12N 2310/122 (20130101)
C12N 2310/141 (20130101)
C12N 2310/322 (20130101)
C12N 2310/3517 (20130101)
C12N 2310/3519 (20130101)
C12N 2310/3533 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964109 Garza et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia);  EMORY UNIVERSITY (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia);  Emory University (Atlanta, Georgia)
INVENTOR(S) Kristie Michelle Garza (Decatur, Georgia);  Annabelle C. Singer (Atlanta, Georgia);  Levi Wood (Atlanta, Georgia);  Abigail L. Paulson (Atlanta, Georgia)
ABSTRACT Methods for controlling brain activity in a subject are described herein. An example method can include delivering a stimulus to the subject, wherein the stimulus induces neural activity in the subjects brain and modulates expression of at least one soluble mediator of cellular activity (such as, for example, a cytokine, chemokine, and/or growth factor) within the subject, and the stimulus is delivered to the subject for less than one hour.
FILED Monday, March 11, 2019
APPL NO 16/979226
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 21/00 (20130101) Original (OR) Class
A61M 2021/0027 (20130101)
A61M 2021/0044 (20130101)
A61M 2021/0055 (20130101)
A61M 2021/0072 (20130101)
A61M 2250/00 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/36025 (20130101)
A61N 2/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964252 Shaikh et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Prostate Cancer Research Program (USAMRMCPCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) XPLOSAFE, LLC (Stillwater, Oklahoma)
ASSIGNEE(S) XPLOSAFE, LLC (Stillwater, Oklahoma)
INVENTOR(S) Shoaib F. Shaikh (Stillwater, Oklahoma);  Allen W. Apblett (Stillwater, Oklahoma);  Nicholas F. Materer (Stillwater, Oklahoma);  Evgueni Kadossov (Stillwater, Oklahoma);  Michael L. Teicheira (Stillwater, Oklahoma)
ABSTRACT The present invention provides an improved sorbent and corresponding device(s) and uses thereof for the capture and stabilization of volatile organic compounds (VOC) or semi-volatile organic compounds (SVOC) from a gaseous atmosphere. The sorbent is capable of rapid and high uptake of one or more compounds and provides quantitative release (recovery) of the compound(s) when exposed to elevated temperature and/or organic solvent. Uses of particular improved grades of mesoporous silica are disclosed.
FILED Monday, January 25, 2021
APPL NO 17/157526
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 2253/106 (20130101)
B01D 2257/708 (20130101)
B01D 2259/4583 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/103 (20130101) Original (OR) Class
B01J 20/3204 (20130101)
B01J 20/3219 (20130101)
B01J 20/3246 (20130101)
B01J 20/3293 (20130101)
B01J 20/28021 (20130101)
B01J 20/28064 (20130101)
B01J 20/28073 (20130101)
B01J 20/28076 (20130101)
B01J 20/28083 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 33/18 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/82 (20130101)
C01P 2004/04 (20130101)
C01P 2004/13 (20130101)
C01P 2006/12 (20130101)
C01P 2006/14 (20130101)
C01P 2006/16 (20130101)

Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 21/0091 (20130101)
C06B 23/00 (20130101)
C06B 45/00 (20130101)

Blasting
F42D 5/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964944 McLeod et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Chemical Biological Center (CCDC CBC)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The University of Chicago (Chicago, Illinois);  University of Leeds (Leeds, United Kingdom);  The J. Craig Venter Institute (Rockville, Maryland);  Institute For Systems Biology (Seattle, Washington);  U.S. Government, as represented by The Secretary of The Army Medical Command (MEDCOM) (Fort Detrick, Maryland);  The University of Strathclyde (Glasgow, United Kingdom)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois);  J. Craig Venter Institute, Inc. (Ajolla, California);  The University of Sheffield (, United Kingdom);  Institute for Systems Biology (Seattle, Washington);  The University of Leeds (, United Kingdom);  The University of Strathclyde (, United Kingdom);  The Government of the United States (Fort Detrick, Maryland)
INVENTOR(S) Rima McLeod (Chicago, Illinois);  Martin McPhillie (Leeds, United Kingdom);  Colin W. G. Fishwick (Leeds, United Kingdom);  Hernan Alejandro Lorenzi (Rockville, Maryland);  Kai Wang (Seattle, Washington);  Taek-Kyun Kim (Seattle, Washington);  Yong Zhou (Seattle, Washington);  Leroy E. Hood (Seattle, Washington);  Ying Zhou (Chicago, Illinois);  Kamal El Bissati (Chicago, Illinois);  Mark Hickman (Silver Spring, Maryland);  QiGui Li (Silver Spring, Maryland);  Craig Roberts (Glasgow, United Kingdom)
ABSTRACT Disclosed herein are novel compounds for treating apicomplexan parasite related disorders, methods for their use; cell line and non-human animal models of the dormant parasite phenotype and methods for their use in identifying new drugs to treat apicomplexan parasite related disorders, and biomarkers to identify disease due to the parasite and its response to treatment.
FILED Thursday, June 02, 2022
APPL NO 17/831049
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 33/06 (20180101)

Heterocyclic Compounds
C07D 215/233 (20130101) Original (OR) Class
C07D 401/12 (20130101)
C07D 405/12 (20130101)
C07D 471/04 (20130101)
C07D 487/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964945 Crew et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Arvinas Operations, Inc. (New Haven, Connecticut)
ASSIGNEE(S) Arvinas Operations, Inc. (New Haven, Connecticut)
INVENTOR(S) Andrew P. Crew (Chester, Connecticut);  Keith R. Hornberger (Southbury, Connecticut);  Lawrence B. Snyder (Killingworth, Connecticut);  Kurt Zimmermann (Durham, Connecticut);  Jing Wang (Milford, Connecticut);  Hanqing Dong (Madison, Connecticut)
ABSTRACT The present disclosure relates to bifunctional compounds, which find utility to degrade and (inhibit) Androgen Receptor. In particular, the present disclosure is directed to compounds, which contain on one end a cereblon ligand which binds to the E3 ubiquitin ligase and on the other end a moiety which binds Androgen Receptor, such that Androgen Receptor is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of Androgen Receptor. The present disclosure exhibits a broad range of pharmacological activities associated with compounds according to the present disclosure, consistent with the degradation/inhibition of Androgen Receptor.
FILED Friday, May 29, 2020
APPL NO 16/888484
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/02 (20130101)
A61K 31/166 (20130101)
A61K 31/277 (20130101)
A61K 31/496 (20130101)
A61K 31/497 (20130101)
A61K 31/501 (20130101)
A61K 31/506 (20130101)
A61K 45/06 (20130101)
A61K 47/10 (20130101)

Heterocyclic Compounds
C07D 205/04 (20130101)
C07D 209/48 (20130101)
C07D 211/76 (20130101)
C07D 213/72 (20130101)
C07D 221/20 (20130101)
C07D 231/12 (20130101)
C07D 233/42 (20130101) Original (OR) Class
C07D 237/08 (20130101)
C07D 239/24 (20130101)
C07D 241/04 (20130101)
C07D 401/04 (20130101)
C07D 401/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964956 Makriyannis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Alexandros Makriyannis (Watertown, Massachusetts);  Spyridon P. Nikas (Newton, Massachusetts);  Ganeshsingh A. Thakur (Boston, Massachusetts);  Rishi Sharma (Revere, Massachusetts);  Shashank Kulkarni (Billerica, Massachusetts)
ABSTRACT Disclosed are compounds and compositions that modulate cannabinoid receptors, methods of modulating cannabinoid receptors, and methods of treating various disorders related to the modulation of cannabinoid receptors. This disclosure is directed to methods of treating cannabinoid dependence, neuropathy, inflammation, glaucoma, a neurodegenerative disorder, a motor function disorder, a gastrointestinal disorder, hypothermia, emesis, loss of appetite, or anorexia associated with AIDS.
FILED Friday, December 11, 2020
APPL NO 17/119836
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 57/58 (20130101)
C07C 255/57 (20130101)

Heterocyclic Compounds
C07D 311/80 (20130101) Original (OR) Class
C07D 405/12 (20130101)
C07D 407/04 (20130101)
C07D 493/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964984 Natarajan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) CITY OF HOPE (Duarte, California)
ASSIGNEE(S) CITY OF HOPE (Duarte, California)
INVENTOR(S) Rama Natarajan (Hacienda Heights, California);  Feng Miao (Alhambra, California);  Nagarajan Vaidehi (Arcadia, California);  Supriyo Bhattacharya (Monrovia, California)
ABSTRACT Disclosed herein, inter alia, are compounds and methods for inhibiting the thioredoxin-thioredoxin-interacting-protein (TXNIP-TRX) complex.
FILED Thursday, April 15, 2021
APPL NO 17/231743
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)
A61P 37/06 (20180101)

Heterocyclic Compounds
C07D 491/048 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964985 Theodorescu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE. (Denver, Colorado);  INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana);  UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia)
INVENTOR(S) Dan Theodorescu (Englewood, Colorado);  Michael Fitzpatrick Wempe (Aurora, Colorado);  David Ross (Niwot, Colorado);  Samy Meroueh (Westfield, Indiana);  Martin A. Schwartz (Earlysville, Virginia);  Phillip Reigan (Denver, Colorado)
ABSTRACT The invention provides methods of inhibiting the growth or metastasis of a cancer in a mammal by inhibiting a Ral GTPase in the mammal. The invention also provides small molecule inhibitors of Ral GTPases useful in the methods of the invention and pharmaceutical compositions containing the therapeutically effective compounds of the invention, and methods of using the same.
FILED Tuesday, May 12, 2020
APPL NO 15/930188
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/351 (20130101)
A61K 31/437 (20130101)
A61K 31/505 (20130101)
A61K 31/4162 (20130101)
A61K 31/5513 (20130101)
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 491/052 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964997 Kazakov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) RealSeq Biosciences, Inc. (Santa Cruz, California)
ASSIGNEE(S) RealSeq Biosciences, Inc. (Santa Cruz, California)
INVENTOR(S) Sergei A. Kazakov (San Jose, California);  Sergio Barberan-Soler (Santa Cruz, California);  Anne Dallas (Santa Cruz, California);  Brian H. Johnston (Scotts Valley, California)
ABSTRACT Disclosed herein are methods and compositions for the detection of small RNAs in a sample. The methods and compositions disclosed herein may be used for preparing sequencing libraries of the small RNAs, fragments of RNAs and DNAs.
FILED Friday, March 12, 2021
APPL NO 17/199968
ART UNIT 1675 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101)
C07H 21/02 (20130101) Original (OR) Class
C07H 21/04 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6855 (20130101)
C12Q 1/6855 (20130101)
C12Q 1/6874 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/191 (20130101)
C12Q 2525/307 (20130101)
C12Q 2531/125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965002 Karginov
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE BD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S) THE BD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S) Andrei Karginov (Chicago, Illinois)
ABSTRACT A light-activated construct composed of two photoreceptive polypeptide domains connected to one another by a flexible linker is provided, as is a fusion protein containing the same and polynucleotides encoding said construct and fusion protein. Methods of making and using the light-activated construct and fusion protein are also provided.
FILED Friday, November 29, 2019
APPL NO 16/699203
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0042 (20130101)
A61K 41/0057 (20130101)
A61K 47/65 (20170801)

Peptides
C07K 14/37 (20130101) Original (OR) Class
C07K 14/415 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/12 (20130101)
C12N 15/90 (20130101)
C12N 2015/859 (20130101)
C12N 2800/30 (20130101)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965006 Deslouches et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Berthony Deslouches (Pittsburgh, Pennsylvania);  Yuanpu Di (Wexford, Pennsylvania)
ABSTRACT This disclosure is directed to compositions comprised of antimicrobial peptides (AMPs) having an alpha helical structure wherein one side is highly hydrophobic. Representative sequences of the antimicrobial peptides include ILKKWWββαβGLLGβLLGαVββVIKβLββI (SEQ ID No. 2), LKKWWKβαKGLLGGLLGKVββVIK (SEQ ID No. 12), and αKKααKKαKGαLGGLαGK (SEQ ID No. 18). Additional embodiments disclose methods for treating a microbial infection; reducing biofilm; decreasing inflammation; and treating infectious diseases, COPD, asthma, pulmonary fibrosis, cystic fibrosis, rhinosinusitis, septicemia, RSV, TB or cancer; in a subject in need thereof comprising administering to the subject a therapeutic amount of an antimicrobial peptide.
FILED Friday, November 19, 2021
APPL NO 17/531100
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/4723 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965009 Bishai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE JOHNS HOPKINS UNIVERSITY (Baltmore, Maryland);  TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland);  Trustees of Boston University (Boston, Massachusetts)
INVENTOR(S) William R. Bishai (Baltimore, Maryland);  John R. Murphy (Tilghman, Maryland);  Laurene Cheung (Baltimore, Maryland);  Shashank Gupta (Frederick, Maryland);  Cynthia K. Bullen (Baltimore, Maryland)
ABSTRACT The present invention is a DNA expression vector comprising: a toxP: a mutant toxO that blocks Fe-mediated regulation of gene expression; and a DNA sequence encoding a protein, wherein the toxP and the mutant toxO regulate expression of the DNA segment encoding the protein. It is preferred that DNA expression vectors of the present invention include DNA sequences encoding a signal peptide so that a protein expressed is attached to the signal peptide prior to processing. Novel proteins are produced off of the DNA expression vector of the present invention.
FILED Monday, December 13, 2021
APPL NO 17/549845
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/34 (20130101)
C07K 14/55 (20130101) Original (OR) Class
C07K 2319/02 (20130101)
C07K 2319/21 (20130101)
C07K 2319/33 (20130101)
C07K 2319/034 (20130101)
C07K 2319/55 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/77 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965034 Wernig et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Gerlinde Wernig (Stanford, California);  Irving L. Weissman (Stanford, California)
ABSTRACT Compositions and methods are provided for treating fibrosis in a mammal by administering a therapeutic dose of a pharmaceutical composition.
FILED Wednesday, February 09, 2022
APPL NO 17/668068
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1774 (20130101)
A61K 39/3955 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 1/16 (20180101)
A61P 11/00 (20180101)

Peptides
C07K 16/2803 (20130101)
C07K 16/2896 (20130101) Original (OR) Class
C07K 2317/76 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/53 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 15/00 (20180101)
G16H 80/00 (20180101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/04 (20130101)
H04L 63/101 (20130101)
H04L 63/107 (20130101)
H04L 63/0281 (20130101)
H04L 63/0442 (20130101)

Wireless Communication Networks
H04W 12/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965159 Choudhary et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Amit Choudhary (Boston, Massachusetts);  Kurt Cox (Cambridge, Massachusetts);  Hari Subramanian (Oakland, California);  Elisa Franco (Oakland, California)
ABSTRACT Compositions and methods for conditionally regulating activities of CRISPR-Cas systems. In some embodiments, the methods comprise providing an inactive guide RNA comprising a regulatory domain bound by a lock nucleic acid different from the guide RNA; and displacing the lock nuclei acid from the regulatory domain by a trigger nucleic acid, thereby activating the guide RNA, wherein the activated guide RNA forms a complex with a Cas enzyme.
FILED Wednesday, January 29, 2020
APPL NO 16/776503
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 38/465 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101) Original (OR) Class
C12N 15/67 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 2310/20 (20170501)
C12N 2310/50 (20130101)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965160 Nimjee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Duke University (Durham, North Carolina);  Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Duke University (Durham, North Carolina);  Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Shahid M. Nimjee (Columbus, Ohio);  Bruce Sullenger (Durham, North Carolina);  George A. Pitoc (Durham, North Carolina);  Juliana Layzer (Durham, North Carolina)
ABSTRACT Provided herein are aptamers capable of inhibiting the activity of Von Willebrand Factor (VWF). Pharmaceutical compositions comprising these aptamers are also provided. Methods of preventing blood clot formation in a subject by administering the aptamers are provided and methods of treating a blood clot by administering a VWF-targeting agent are also provided.
FILED Monday, January 11, 2021
APPL NO 17/146147
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)
A61K 31/7105 (20130101)
A61K 31/7105 (20130101)
A61K 31/7115 (20130101)
A61K 31/7115 (20130101)
A61K 45/06 (20130101)
A61K 47/60 (20170801)
A61K 47/64 (20170801)
A61K 47/554 (20170801)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/02 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 15/115 (20130101)
C12N 2310/16 (20130101)
C12N 2310/113 (20130101)
C12N 2310/317 (20130101)
C12N 2310/321 (20130101)
C12N 2310/322 (20130101)
C12N 2310/3183 (20130101)
C12N 2310/3515 (20130101)
C12N 2310/3521 (20130101)
C12N 2310/3533 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965162 Jaffee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Elizabeth A. Jaffee (Baltimore, Maryland);  Nina Chu (Baltimore, Maryland);  Jacquelyn Winifred Zimmerman (Baltimore, Maryland)
ABSTRACT In one aspect, compositions are provided for the early diagnosis and treatment of pancreatic ductal adenocarcinoma and include microRNAs, e.g. miR-21 and inhibitors thereof. The treatment compositions can be useful for early detection, and for intercepting developing premalignant pancreatic lesions and other KRAS-driven premalignancies.
FILED Friday, April 16, 2021
APPL NO 17/233378
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7088 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/178 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965164 Chilkoti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Ashutosh Chilkoti (Durham, North Carolina);  Stefan Zauscher (Durham, North Carolina);  Lei Tang (Durham, North Carolina);  Sonal Deshpande (Durham, North Carolina)
ABSTRACT Compositions and methods disclosed herein can help provide improved delivery of non-natural therapeutic nucleotides for the treatment of diseases such as cancer. An example composition includes an assembly of amphiphilic polynucleotides, where each amphiphilic polynucleotide includes an aptamer portion, a first nucleotide portion, and a second nucleotide portion.
FILED Monday, October 31, 2022
APPL NO 18/051487
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7105 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 15/115 (20130101)
C12N 2310/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965174 Chatterjee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) City of Hope (Duarte, California)
ASSIGNEE(S) City of Hope (Duarte, California)
INVENTOR(S) Saswati Chatterjee (Duarte, California);  Laura Jane Smith (Duarte, California);  Kamehameha Wong (Duarte, California)
ABSTRACT Adeno-associated virus (AAV) Clade F vectors or AAV vector variants (relative to AAV9) for precise editing of the genome of a cell and methods and kits thereof are provided. Targeted genome editing using the AAV Clade F vectors or AAV vector variants provided herein occurred at frequencies that were shown to be 1,000 to 100,000 fold more efficient than has previously been reported. Also provided are methods of treating a disease or disorder in a subject by editing the genome of a cell of the subject via transducing the cell with an AAV Clade F vector or AAV vector variant as described herein and further transplanting the transduced cell into the subject to treat the disease or disorder of the subject. Also provided herein are methods of treating a disease or disorder in a subject by in vivo genome editing by directly administering the AAV Clade F vector or AAV vector variant as described herein to the subject.
FILED Tuesday, July 26, 2022
APPL NO 17/815065
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)
A61K 48/005 (20130101)
A61K 48/0008 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 15/102 (20130101)
C12N 15/907 (20130101) Original (OR) Class
C12N 2710/16622 (20130101)
C12N 2750/14121 (20130101)
C12N 2750/14122 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14145 (20130101)
C12N 2750/14152 (20130101)
C12N 2750/14171 (20130101)
C12N 2800/70 (20130101)
C12N 2840/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965190 Kaznessis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Yiannis John Kaznessis (New Brighton, Minnesota);  Seth Ritter (Minneapolis, Minnesota);  Benjamin Hackel (Edina, Minnesota)
ABSTRACT Provided herein are a vector, a genetically modified bacterium including the vector, methods of making the bacterium, methods of using the bacterium, and kits including the bacterium. The vector includes a coding region encoding at least one antimicrobial peptide, and the antimicrobial peptide includes at least one lysin.
FILED Friday, September 07, 2018
APPL NO 16/645281
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/747 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)
C12N 9/2462 (20130101) Original (OR) Class
C12N 15/62 (20130101)
C12N 15/74 (20130101)
C12N 15/635 (20130101)
C12N 15/746 (20130101)

Enzymes
C12Y 302/01017 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965215 Kurtz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) David M. Kurtz (San Carlos, California);  Maximilian Diehn (San Carlos, California);  Arash Ash Alizadeh (San Mateo, California)
ABSTRACT Processes and materials to detect cancer from a biopsy are described. In some cases, cell-free nucleic acids can be sequenced, and the sequencing result can be utilized to detect sequences derived from a neoplasm. Detection of somatic variants occurring in phase can indicate the presence of cancer in a diagnostic scan and a clinical intervention can be performed.
FILED Friday, February 10, 2023
APPL NO 18/167804
ART UNIT 1672 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1089 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101)
C12Q 1/6874 (20130101)
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/112 (20130101)
C12Q 2600/156 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 2800/7028 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/00 (20190201)
G16B 20/10 (20190201)
G16B 20/20 (20190201)
G16B 30/00 (20190201)
G16B 30/10 (20190201)
G16B 35/20 (20190201)
G16B 40/00 (20190201)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 10/40 (20180101)
G16H 10/60 (20180101)
G16H 20/10 (20180101)
G16H 50/20 (20180101)
G16H 50/30 (20180101)
G16H 50/70 (20180101)
G16H 70/60 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965218 Foxman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Yale University (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) Ellen Foxman (West Hartford, Connecticut);  Marie Landry (Guilford, Connecticut)
ABSTRACT The present disclosure concerns methods of detecting viral respiratory infections by analyzing biomarkers in a viral transport medium sample. In various embodiments the biomarkers are assessed by measuring mRNA or protein. In certain embodiments the biomarkers are nasal-virus induced molecules.
FILED Wednesday, October 11, 2017
APPL NO 16/340328
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/70 (20130101) Original (OR) Class
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101)
G01N 2333/7158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965810 Swami et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia);  Nathan Swami (Charlottesville, Virginia);  John McGrath (Charlottesville, Virginia);  Walter Varhue (Glen Allen, Virginia);  Carlos Honrado (Charlottesville, Virginia);  Vahid Farmehini (Charlottesville, Virginia);  Yi Liu (Charlottesville, Virginia)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Nathan Swami (Charlottesville, Virginia);  John McGrath (Charlottesville, Virginia);  Walter Varhue (Glen Allen, Virginia);  Carlos Honrado (Charlottesville, Virginia);  Vahid Farmehini (Charlottesville, Virginia);  Yi Liu (Charlottesville, Virginia)
ABSTRACT An exemplary method and system is disclosed that facilitate the integration of multiplexed single-cell impedance cytometry in a high throughput format, which can be deployed upstream from microfluidic sample preparation and/or downstream to microfluidic cell separation. In exemplary method and system may employ impedance-based quantification of cell electrophysiology on the same microfluidic chip (i.e., “on-chip”) to provide distinguishing phenotypic information on the sample, without the need for additional sample handling, preparation or dilution steps as would be needed for other flow cytometry techniques.
FILED Thursday, September 26, 2019
APPL NO 17/280480
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502761 (20130101)
B01L 2200/10 (20130101)
B01L 2200/027 (20130101)
B01L 2200/0652 (20130101)
B01L 2300/0645 (20130101)
B01L 2400/0424 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/1031 (20130101)
G01N 15/1056 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965812 Vacca et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Kinetic River Corp. (Mountain View, California)
ASSIGNEE(S) Kinetic River Corp. (Mountain View, California)
INVENTOR(S) Giacomo Vacca (Aptos, California);  Ralph Jimenez (Boulder, Colorado)
ABSTRACT Described herein are apparatuses and methods for analyzing an optical signal decay. In some embodiments, an apparatus includes: a source of a beam of pulsed optical energy; a sample holder configured to expose a sample to the beam; a detector comprising a number of spectral detection channels configured to convert the optical signals into respective electrical signals; and a signal processing module configured to perform a method. In some embodiments, the method includes: receiving the electrical signals from the detector; mathematically combining individual decay curves in the electrical signals into a supercurve, the supercurve comprising a number of components, each component having a time constant and a relative contribution to the supercurve; and quantifying a relative contribution of each component to the supercurve.
FILED Tuesday, July 11, 2023
APPL NO 18/350336
ART UNIT 2878 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/14 (20130101) Original (OR) Class
G01N 15/147 (20130101)
G01N 15/1429 (20130101)
G01N 15/1434 (20130101)
G01N 15/1436 (20130101)
G01N 2015/144 (20130101)
G01N 2015/149 (20130101)
G01N 2015/1006 (20130101)
G01N 2015/1438 (20130101)
G01N 2015/1477 (20130101)
G01N 2015/1488 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965840 Deerinck et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Thomas Deerinck (La Jolla, California);  Mark Ellisman (La Jolla, California);  Steven Peltier (La Jolla, California)
ABSTRACT An epoxy resin-based embedding media doped with a non-conductive dopant to a predetermined w/w % such that the media is non-charging at 1.8 keV. A preferred dopant is polyethylene glycol at a molecular weight of at least 3350, and having a predetermined w/w % is at least 2% and up to 20%, most preferably from 2% to 10%. Another preferred dopant is polyethylene glycol at a molecular weight of 7000-8000 and a predetermined w/w % of up to ˜40% and more preferably of up to ˜30%.
FILED Friday, April 23, 2021
APPL NO 17/238530
ART UNIT 2881 — Optics
CURRENT CPC
Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/22 (20130101)
C08K 5/06 (20130101)
C08K 2003/222 (20130101)

Compositions of Macromolecular Compounds
C08L 63/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/36 (20130101)
G01N 23/2251 (20130101) Original (OR) Class
G01N 2001/364 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965851 Thompson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) David H. Thompson (West Lafayette, Indiana);  Christopher Benjamin (Sunnyvale, California);  Kyle Wright (Lafayette, Indiana);  Scott C. Bolton (West Lafayette, Indiana);  Seok-Hee Hyun (West Lafayette, Indiana)
ABSTRACT Methods of using grids in connection with suitable microscopy techniques, such as for determining the structure of target compounds including proteins, are disclosed. Said grid comprising a coating modified with one or more capture agents and a deactivating agent.
FILED Wednesday, October 21, 2020
APPL NO 17/075793
ART UNIT 1678 — Optics
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/192 (20170801)

Peptides
C07K 1/14 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/30 (20130101)
G01N 27/127 (20130101) Original (OR) Class
G01N 27/4145 (20130101)
G01N 2223/418 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 37/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965881 Motamedi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Science Foundation (NSF)
APPLICANT(S) The Board of Regents of The University of Texas System (Austin, Texas);  Kansas State University Research Foundation (Manhattan, Kansas)
ASSIGNEE(S) Kansas State University Research Foundation (Manhattan, Kansas);  Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S) Massoud Motamedi (Houston, Texas);  Allan R. Brasier (Galveston, Texas);  Stefan H. Bossmann (Manhattan, Kansas);  Christopher T. Culbertson (Manhattan, Kansas);  Deryl Troyer (Manhattan, Kansas)
ABSTRACT Methods and devices for microfluidic detection of a biological maker in a biospecimen collected from a subject are disclosed. The microfluidic devices include nanoparticle-based nanosensors comprising supramolecular recognition sequences, protease consensus sequences, post-translationally modifiable sequences, or sterically hindered benzylether bonds for specific interaction with a biological marker. Also disclosed are particular nanosensors for detecting cytokines, and other proteins based upon supramolecular recognition without chemical modification or enzymatic cleavage.
FILED Friday, March 24, 2017
APPL NO 16/088407
ART UNIT 1678 — Optics
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 2300/0636 (20130101)
B01L 2300/0816 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
G01N 33/54346 (20130101) Original (OR) Class
G01N 2333/70596 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965890 Ruthenburg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
ASSIGNEE(S) THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S) Alexander J. Ruthenburg (Chicago, Illinois);  Adrian Grzybowski (Chicago, Illinois);  Zhonglei Chen (Evanston, Illinois)
ABSTRACT One aspect of the present invention describes materials and methods of quantitatively measuring the density or percent occupancy of DNA binding proteins such as histones, histone variants, histone post translational modifications and transcription factors in chromatin at given DNA loci. One embodiment measures a factor's average quantity at specific gene loci, and controls for a number of pitfalls concerning antibody quality and handling issues. Other embodiments include calibrating and quantifying chromatin immunoprecipitation assays, assessing an affinity reagent specificity, as well as required reagents and their formulation in kits. Another embodiment allows for the diagnosis of a condition or disease by measuring the density of a histone modification at a genomic locus.
FILED Friday, June 19, 2020
APPL NO 16/906513
ART UNIT 1675 — Optics
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 2522/101 (20130101)
C12Q 2535/122 (20130101)
C12Q 2545/101 (20130101)
C12Q 2563/179 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6875 (20130101) Original (OR) Class
G01N 2440/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965950 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Siemens Healthineers AG (Forchheim, Germany);  Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Siemens Healthineers AG (Forchheim, Germany);  Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Xiufeng Li (Shoreview, Minnesota);  Gregory J. Metzger (Lake Elmo, Minnesota);  Essa Yacoub (Hudson, Wisconsin);  Kamil Ugurbil (Minneapolis, Minnesota);  Dingxin Wang (Apple Valley, Minnesota)
ABSTRACT A method for generating a perfusion weighted image using arterial spin labeling (ASL) with segmented acquisitions includes dividing an anatomical area of interest into a plurality of slices and performing a multi-band (MB) echo planar imaging (EPI) acquisition process using a magnetic resonance imaging (MRI) system to acquire a control image dataset representative of the plurality of slices using a central-to-peripheral or peripheral-to-central slice acquisition order. An ASL preparation process is performed using the MRI system to magnetically label protons in arterial blood water in an area upstream from the anatomical area of interest. Following a post-labeling delay time period, the MB EPI acquisition process is performed to a labeled image dataset corresponding to the slices using the central-to-peripheral or peripheral-to-central slice acquisition order. A perfusion weighted image of the anatomical area is generated by subtracting the labeled image dataset from the control image dataset.
FILED Monday, July 29, 2019
APPL NO 16/524254
ART UNIT 3798 — Optics
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4835 (20130101)
G01R 33/5611 (20130101)
G01R 33/5616 (20130101)
G01R 33/56366 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967064 Constance et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Morgan State University (Baltimore, Maryland)
ASSIGNEE(S) Morgan State University (Baltimore, Maryland)
INVENTOR(S) Edward Constance (Washington, District of Columbia);  Kadir Aslan (Towson, Maryland);  Enock Bonyi (Rosedale, Maryland)
ABSTRACT Systems and methods are provided for the rapid sensing of biological and environmental analytes employing a portable digital image capture device, such as a smartphone camera, to capture an image of colorimetric microwave-accelerated bioassays (“MAB”), and a digital image analyzer that processes the colorimetric signals captured by the digital camera to determine the concentration of analyte in a test sample based on a calculated pixel intensity in the captured digital image. Such systems and methods may be used to detect either a disease condition or the presence of a toxin in a particular test specimen and may generate an electronic alert that may serve to alert a medical practitioner of such disease condition or presence of a toxin so that medical intervention may be undertaken. Such electronic alert may optionally be transmitted to the user of a smartphone that captured the image, thus allowing for rapid, in-situ point-of-care analysis and detection of such conditions and immediate medical intervention.
FILED Wednesday, March 17, 2021
APPL NO 17/204194
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/31 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/90 (20170101)
G06T 2207/10024 (20130101)
G06T 2207/30072 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967070 Ay et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Hakan Ay (Boston, Massachusetts);  Jayashree Kalpathy-Cramer (Boston, Massachusetts)
ABSTRACT An image analysis system including at least one processor and at least one memory is provided. The image analysis system is configured to receive image data associated with a brain of a patient, the image data including a first three-dimensional (3D) diffusion weighted imaging (DWI) image acquired using a magnetic resonance imaging (MRI) system and a second 3D DWI image, concurrently provide the first 3D DWI image to a first channel of a trained model and the second 3D DWI image to a second channel of the trained model, receive an indicator associated with the first 3D DWI image and the second 3D DWI image from the model, generate a report based on the indicator, and cause the report to be output to at least one of a memory or a display.
FILED Wednesday, May 13, 2020
APPL NO 17/611394
ART UNIT 2683 — Telemetry and Code Generation Vehicles and System Alarms
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0042 (20130101)
A61B 5/055 (20130101)
A61B 5/742 (20130101)
A61B 5/7267 (20130101)
A61B 5/7275 (20130101)
A61B 2576/026 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/5608 (20130101)
G01R 33/56341 (20130101)

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 2200/04 (20130101)
G06T 2207/10092 (20130101)
G06T 2207/20076 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/30016 (20130101)
G06T 2207/30096 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967410 Blakely et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
APPLICANT(S) Meso Scale Technologies, LLC. (Rockville, Maryland);  THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland)
ASSIGNEE(S) Meso Scale Technologies, LLC (Rockville, Maryland);  THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland)
INVENTOR(S) William F Blakely (Silver Spring, Maryland);  Eli N. Glezer (Del Mar, California);  John Kenten (Boyds, Maryland);  Sudeep Kumar (Gaithersburg, Maryland);  Anu Mathew (North Potomac, Maryland);  Natalia I. Ossetrova (Silver Spring, Maryland);  George Sigal (Rockville, Maryland)
ABSTRACT Methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. Also, algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.
FILED Thursday, February 22, 2018
APPL NO 15/902597
ART UNIT 1678 — Recording and Compression
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3273 (20130101)
G01N 33/6893 (20130101)
G01N 35/00 (20130101)
G01N 2333/70535 (20130101)
G01N 2333/70578 (20130101)
G01N 2800/40 (20130101)
G01N 2800/60 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/00 (20130101)
G01T 1/02 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11963697 Hanson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Timothy L. Hanson (San Francisco, California);  Michel M. Maharbiz (El Cerrito, California);  Philip N. Sabes (San Francisco, California)
ABSTRACT Methods, systems, and compositions are provided for implanting an implantable device into a biological tissue (e.g., muscle, brain). A subject implantable device includes: (i) a biocompatible substrate, (ii) a conduit (e.g., an electrode, a waveguide) that is disposed on the biocompatible substrate, and (iii) an engagement feature (e.g., a loop) for reversible engagement with an insertion needle. The biocompatible substrate can be flexible (e.g., can include polyimide). The implantable device is implanted using an insertion needle that includes an engagement feature corresponding to the engagement feature of the implantable device. To implant, an implantable device is reversibly engaged with an insertion needle, the device-loaded insertion needle is inserted into a biological tissue (e.g., to a desired depth), and the insertion needle is retracted, thereby disengaging the implantable device from the insertion needle and allowing the implantable device to remain implanted in the biological tissue.
FILED Tuesday, April 25, 2023
APPL NO 18/138978
ART UNIT 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0084 (20130101)
A61B 5/293 (20210101)
A61B 5/688 (20130101)
A61B 5/1473 (20130101)
A61B 5/6882 (20130101)
A61B 17/3468 (20130101) Original (OR) Class
A61B 2017/00526 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/0531 (20130101)
A61N 1/0534 (20130101)
A61N 1/0539 (20130101)
A61N 5/067 (20210801)
A61N 5/0601 (20130101)
A61N 5/0622 (20130101)
A61N 2005/063 (20130101)
A61N 2005/0651 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963751 Ren et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) LR Technologies, Inc. (Rockville, Maryland)
ASSIGNEE(S) LR TECHNOLOGIES, INC. (Rockville, North Dakota)
INVENTOR(S) Eugene Yu-Jiun Ren (San Marcos, California);  Yexian Qin (Tuscon, Arizona);  Chiehping Lai (Rockville, Maryland)
ABSTRACT The present disclosure includes an electromagnetic field detection and monitoring system. The system includes a single-ended amplifier and an impedance matching circuit which matches the impedance caused by an air gap between tissue and an electrode. The system includes passive detection, active detection, and signal processing capabilities. At least one embodiment includes a body worn system with sensing, processing, communications, and data storage capabilities. The system provides wearable antennas to transfer the EMF energy in its electrical or magnetic forms into the sensor efficiently. A specially designed processing algorithm can process the collected data and generated the results for medical professionals to read and make decisions. The processing can include machine learning technique which decompose an EMF signal into EEG bands to perform feature extraction. The features can then be used to train a machine learning model to classify other EMF signals.
FILED Thursday, November 05, 2020
APPL NO 17/090259
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/05 (20130101) Original (OR) Class
A61B 5/25 (20210101)
A61B 5/363 (20210101)
A61B 5/369 (20210101)
A61B 5/721 (20130101)
A61B 5/6804 (20130101)
A61B 5/7264 (20130101)

Antennas, i.e Radio Aerials
H01Q 1/48 (20130101)
H01Q 1/273 (20130101)
H01Q 1/2291 (20130101)
H01Q 5/335 (20150115)
H01Q 21/28 (20130101)

Selecting
H04Q 9/00 (20130101)
H04Q 9/02 (20130101)
H04Q 2209/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11963959 Bohmann et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
APPLICANT(S) Southwest Research Institute (San Antonio, Texas);  The Government of The United States, as represented by The Secretary of the Army (Fort Detrick, Maryland);  The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
ASSIGNEE(S) Southwest Research Institute (San Antonio, Texas);  The Government of the United States, as represented by The Secretary of the Army (Fort Detrick, Maryland);  The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
INVENTOR(S) Jonathan A. Bohmann (San Antonio, Texas);  Nadean M. Gutierrez (Devine, Texas);  Joseph A. Mcdonough (Helotes, Texas);  Robert Francis Campbell (Edgemere, Maryland);  Michael Gordon Joyce (Silver Spring, Maryland);  Rekha Panchal (Fort Detrick, Maryland);  Rajeshwer Sankhala (Bethesda, Maryland);  Allen Duplantier (Stafford, Virginia)
ABSTRACT Inhibitors against SARS-COV-1, SARS-CoV-2 (Covid-19), MERS-CoV, and variants within each, including methods of treating a subject suffering from such respiratory disease.
FILED Friday, August 12, 2022
APPL NO 17/819524
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/427 (20130101)
A61K 31/517 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964026 Barberio et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Antonio Eric Barberio (Cambridge, Massachusetts);  Santiago Correa Echavarria (Allston, Massachusetts);  Mariane Bandeira Melo (Stoneham, Massachusetts);  Talar Tokatlian (Cambridge, Massachusetts);  Erik Christopher Dreaden (Atlanta, Georgia);  Paula T. Hammond (Newton, Massachusetts);  Darrell J. Irvine (Arlington, Massachusetts)
ABSTRACT Disclosed are particles for delivering cytokinese, such as IL-12, for the treatment of cancer. The particles comprise cytokines non-covalently bound to liposomes, where the liposomes are coated with polyelectrolytes.
FILED Monday, August 22, 2022
APPL NO 17/892496
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/1271 (20130101)
A61K 38/208 (20130101)
A61K 47/544 (20170801)
A61K 47/6911 (20170801) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964252 Shaikh et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Prostate Cancer Research Program (USAMRMCPCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) XPLOSAFE, LLC (Stillwater, Oklahoma)
ASSIGNEE(S) XPLOSAFE, LLC (Stillwater, Oklahoma)
INVENTOR(S) Shoaib F. Shaikh (Stillwater, Oklahoma);  Allen W. Apblett (Stillwater, Oklahoma);  Nicholas F. Materer (Stillwater, Oklahoma);  Evgueni Kadossov (Stillwater, Oklahoma);  Michael L. Teicheira (Stillwater, Oklahoma)
ABSTRACT The present invention provides an improved sorbent and corresponding device(s) and uses thereof for the capture and stabilization of volatile organic compounds (VOC) or semi-volatile organic compounds (SVOC) from a gaseous atmosphere. The sorbent is capable of rapid and high uptake of one or more compounds and provides quantitative release (recovery) of the compound(s) when exposed to elevated temperature and/or organic solvent. Uses of particular improved grades of mesoporous silica are disclosed.
FILED Monday, January 25, 2021
APPL NO 17/157526
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 2253/106 (20130101)
B01D 2257/708 (20130101)
B01D 2259/4583 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/103 (20130101) Original (OR) Class
B01J 20/3204 (20130101)
B01J 20/3219 (20130101)
B01J 20/3246 (20130101)
B01J 20/3293 (20130101)
B01J 20/28021 (20130101)
B01J 20/28064 (20130101)
B01J 20/28073 (20130101)
B01J 20/28076 (20130101)
B01J 20/28083 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 33/18 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/82 (20130101)
C01P 2004/04 (20130101)
C01P 2004/13 (20130101)
C01P 2006/12 (20130101)
C01P 2006/14 (20130101)
C01P 2006/16 (20130101)

Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 21/0091 (20130101)
C06B 23/00 (20130101)
C06B 45/00 (20130101)

Blasting
F42D 5/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964465 Shah et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Defense Threat Reduction Agency (DTRA)
APPLICANT(S) LaunchBay LLC (North Billerica, Massachusetts)
ASSIGNEE(S) LaunchBay LLC (North Billerica, Massachusetts)
INVENTOR(S) Apoorva P Shah (Burlington, Massachusetts);  Binod Giri (Tewksbury, Massachusetts);  Arjan Giaya (Shrewsbury, Massachusetts)
ABSTRACT A biaxially stretchable laminated fabric composite material includes a four-way stretchable fabric and a barrier film. The barrier film and the fabric are selectively attached at a plurality of individual bond points. When the fabric is in an unstretched state, random folds are formed in the unbonded regions of the barrier film. When the fabric is in a stretched state, the random folds are partially or fully flattened to allow the biaxially stretchable laminated fabric composite material to biaxially stretch.
FILED Thursday, November 17, 2022
APPL NO 18/056441
ART UNIT 1785 — Miscellaneous Articles, Stock Material
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 7/14 (20130101) Original (OR) Class
B32B 27/12 (20130101)
B32B 27/40 (20130101)
B32B 27/306 (20130101)
B32B 37/0076 (20130101)
B32B 37/203 (20130101)
B32B 38/1875 (20130101)
B32B 2038/0076 (20130101)
B32B 2250/04 (20130101)
B32B 2305/18 (20130101)
B32B 2329/04 (20130101)
B32B 2375/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964748 Slocum et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) LTAG SYSTEMS LLC (Bow, New Hampshire)
ASSIGNEE(S) LTAG SYSTEMS LLC (Bow, New Hampshire)
INVENTOR(S) Jonathan T. Slocum (Bow, New Hampshire);  Alexander H. Slocum (Bow, New Hampshire)
ABSTRACT According to one aspect, a system for launching an aerostat may include an inflatable structure defining a volume having a neck, a reactor defining a chamber, a coupling releasably secured in fluid communication between the chamber and the neck, and a drain valve within the volume, the drain valve in a first position away from the neck to receive a lifting gas from the chamber into the volume via the coupling, the drain valve movable from the first position to a second position when the coupling is released from fluid communication between the chamber and the neck, and the drain valve in the second position in sealed engagement with the inflatable structure along the neck to control accumulation of condensate from the lifting gas within the volume.
FILED Thursday, January 27, 2022
APPL NO 17/586759
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Lighter-than Air Aircraft
B64B 1/40 (20130101)
B64B 1/62 (20130101)
B64B 1/64 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964944 McLeod et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Chemical Biological Center (CCDC CBC)
Defense Threat Reduction Agency (DTRA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The University of Chicago (Chicago, Illinois);  University of Leeds (Leeds, United Kingdom);  The J. Craig Venter Institute (Rockville, Maryland);  Institute For Systems Biology (Seattle, Washington);  U.S. Government, as represented by The Secretary of The Army Medical Command (MEDCOM) (Fort Detrick, Maryland);  The University of Strathclyde (Glasgow, United Kingdom)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois);  J. Craig Venter Institute, Inc. (Ajolla, California);  The University of Sheffield (, United Kingdom);  Institute for Systems Biology (Seattle, Washington);  The University of Leeds (, United Kingdom);  The University of Strathclyde (, United Kingdom);  The Government of the United States (Fort Detrick, Maryland)
INVENTOR(S) Rima McLeod (Chicago, Illinois);  Martin McPhillie (Leeds, United Kingdom);  Colin W. G. Fishwick (Leeds, United Kingdom);  Hernan Alejandro Lorenzi (Rockville, Maryland);  Kai Wang (Seattle, Washington);  Taek-Kyun Kim (Seattle, Washington);  Yong Zhou (Seattle, Washington);  Leroy E. Hood (Seattle, Washington);  Ying Zhou (Chicago, Illinois);  Kamal El Bissati (Chicago, Illinois);  Mark Hickman (Silver Spring, Maryland);  QiGui Li (Silver Spring, Maryland);  Craig Roberts (Glasgow, United Kingdom)
ABSTRACT Disclosed herein are novel compounds for treating apicomplexan parasite related disorders, methods for their use; cell line and non-human animal models of the dormant parasite phenotype and methods for their use in identifying new drugs to treat apicomplexan parasite related disorders, and biomarkers to identify disease due to the parasite and its response to treatment.
FILED Thursday, June 02, 2022
APPL NO 17/831049
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 33/06 (20180101)

Heterocyclic Compounds
C07D 215/233 (20130101) Original (OR) Class
C07D 401/12 (20130101)
C07D 405/12 (20130101)
C07D 471/04 (20130101)
C07D 487/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965001 Piraner et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Interior (DOI)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Dan I. Piraner (San Francisco, California);  Mikhail Shapiro (Pasadena, California)
ABSTRACT Provided herein are thermomer monomer, thermomer dimers, thermomer monomeric constructs, thermomer dimeric complexes, and related gene expression cassette vectors, cells, surfaces devices, compositions methods and systems, that provide a thermobioswitch suitable to control location and/or binding of cargo moiety of interest in a temperature regulated manner.
FILED Monday, July 13, 2020
APPL NO 16/927590
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/255 (20130101) Original (OR) Class
C07K 2319/73 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965159 Choudhary et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Amit Choudhary (Boston, Massachusetts);  Kurt Cox (Cambridge, Massachusetts);  Hari Subramanian (Oakland, California);  Elisa Franco (Oakland, California)
ABSTRACT Compositions and methods for conditionally regulating activities of CRISPR-Cas systems. In some embodiments, the methods comprise providing an inactive guide RNA comprising a regulatory domain bound by a lock nucleic acid different from the guide RNA; and displacing the lock nuclei acid from the regulatory domain by a trigger nucleic acid, thereby activating the guide RNA, wherein the activated guide RNA forms a complex with a Cas enzyme.
FILED Wednesday, January 29, 2020
APPL NO 16/776503
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 38/465 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101) Original (OR) Class
C12N 15/67 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 2310/20 (20170501)
C12N 2310/50 (20130101)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965191 Gao et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Xiaojing Gao (Pasadena, California);  Lucy S. Chong (Pasadena, California);  Michael Elowitz (Pasadena, California);  Mark William Budde (Pasadena, California);  Matthew Sun-min Kim (Pasadena, California)
ABSTRACT The present disclosure relates to systems, methods and compositions provided herein that include a compound protease. The compound protease can contain a protease domain, a cut site for another enzyme and an association domain. In some embodiments, the compound protease is part of a protein circuit.
FILED Monday, January 25, 2021
APPL NO 17/157880
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 2319/50 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/003 (20130101)
C12N 9/96 (20130101)
C12N 9/506 (20130101) Original (OR) Class

Enzymes
C12Y 105/01003 (20130101)
C12Y 304/21098 (20130101)
C12Y 304/22044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965265 Sapiro et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) David Sapiro (King George, Virginia);  Gabriel Bjerke (King George, Virginia)
ABSTRACT An in-situ method for changing surface features of a metal workpiece. An electrically conductive workpiece is immersed in a bath containing an electrolyte solution devoid of ions corresponding to the workpiece. A counter electrode is immersed in the bath. An electric power supply is connected to the workpiece and the counter electrode. An electric current is passed in a first direction between the workpiece and the counter electrode, while the workpiece serves as an anode. The electric current polarity is reversed to pass the electric current in a second direction between the metallic workpiece and the electrode, while the workpiece serves as a cathode. The electric current polarity in the first direction drives ions from the workpiece into the electrolyte solution, and the electric current polarity in the second direction plates the ions onto the workpiece in the same bath.
FILED Thursday, January 30, 2020
APPL NO 16/873076
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 3/02 (20130101)
C25D 5/18 (20130101)
C25D 5/34 (20130101)
C25D 5/605 (20200801)
C25D 21/14 (20130101)

Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor
C25F 3/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965492 Hansen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) Thomas E Hansen (Newport, Rhode Island);  Lewis B Shattuck, IV (Newport, Rhode Island);  Simon E Freeman (Portsmouth, Rhode Island);  Rylan C King (Burke, Virginia)
ABSTRACT A shape memory alloy composite fabric and a method of use is provided in underwater pressure vessels and as flexible joints in atmospheric diving suits. The atmospheric diving suit internal pressure is one atmosphere for underwater transit to and from an underwater work site. During operations at a work site, the shape memory alloy joints transform to a martensite phase and enable greater flexibility while the pressure in the atmospheric diving suit equalizes with ambient depth pressure.
FILED Wednesday, July 21, 2021
APPL NO 17/381231
ART UNIT 3617 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 5/22 (20130101)

Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 3/14 (20130101)
B63B 2005/242 (20130101)

Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects
B63C 11/04 (20130101)

Woven Fabrics; Methods of Weaving; Looms
D03D 15/00 (20130101)

Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles
D10B 2401/02 (20130101)
D10B 2401/06 (20130101)
D10B 2401/046 (20130101)

Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for
F03G 7/06143 (20210801) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965528 Heeter et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana);  Rolls-Royce Corporation (Indianapolis, Indiana)
ASSIGNEE(S) Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana);  Rolls-Royce Corporation (Indianapolis, Indiana)
INVENTOR(S) Robert W. Heeter (Indianapolis, Indiana);  Daniel E. Molnar, Jr. (Indianapolis, Indiana);  Jonathan M. Rivers (Indianapolis, Indiana)
ABSTRACT A fan case assembly adapted for use with a gas turbine engine includes a case at extends circumferentially at least partway about an axis of the gas turbine engine and a plurality of vanes. The case is formed to define a plenum that extends circumferentially at least partway about the axis. The plurality of vanes are arranged in the plenum and spaced apart circumferentially about the axis to define a plurality of inlet openings in fluid communication with the plenum.
FILED Wednesday, August 16, 2023
APPL NO 18/234661
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Jet-propulsion Plants
F02K 3/06 (20130101)

Non-positive-displacement Pumps
F04D 29/68 (20130101)
F04D 29/526 (20130101)
F04D 29/542 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/36 (20130101)
F05D 2240/12 (20130101)
F05D 2240/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965715 Cole et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Surface Warfare Center (NSWC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Crane, Indiana)
ASSIGNEE(S) The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Aaron Boyd Cole (Bloomington, Indiana);  John D. Rodriguez (San Diego, California)
ABSTRACT Provided is a tool for providing long distance shooters with the ability to receive information from others in the field to adjust their weapon system for the best advantage based on distance, location, and range. The tool may implemented as an application on a mobile device such as a smart phone, for example, making the tool light weight, space efficient, and portable for use in the field. The communication ability allows for tracking shooting partners as well as on-the-spot coordination. The tool further provides range markings, yard lines, and topographic data that allow the shooter to make decisions based on real time data. Shooters are therefore afforded a tool that is portable, easy to use, and flexible enough to use in high-pressure environments.
FILED Monday, October 31, 2022
APPL NO 17/977299
ART UNIT 2876 — Optics
CURRENT CPC
Weapon Sights; Aiming
F41G 3/165 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965800 Coombs et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) James M Coombs (Newport, Rhode Island);  David E Baumgarte (Mystic, Connecticut)
ABSTRACT A device for testing the interface to periscope inboard electronics is provided with an enclosure having a cable connector for a plurality of cables from a periscope mast. Each cable includes electric wires, fiber optic lines, radio frequency lines, and video lines. A plurality of interface panels are mounted on the enclosure. Each interface panel is associated with a cable of the plurality of cables. Each interface panel has test points for each voltage conducting cable, video path, and fiber optic line for the associated cable and status indicators for the device and inboard electronics. A multi-position switch is mounted on the enclosure and can be selected for one of a plurality of periscope mast types.
FILED Friday, September 10, 2021
APPL NO 17/471264
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers
B63G 8/38 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 11/3154 (20130101) Original (OR) Class

Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/008 (20130101)

Optical Elements, Systems, or Apparatus
G02B 23/08 (20130101)
G02B 23/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11966138 Lentz
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Joshua Lentz (Niceville, Florida)
ABSTRACT A projector includes a beam homogenizer receiving light from a light source and creating a predetermined illumination, and a spatial light modulator including grating stages to receive the predetermined illumination. Each grating stage may include a plurality of pixels where corresponding pixels in the grating stages are aligned with one another. Each of the pixels may include a liquid crystal layer disposed between two substrates, where a pixel is switchable by applying a voltage thereto, with a grating period of the pixel selected such that, when the voltage is applied to the pixel and light is passed therethrough, optical energy from the light in plus and minus first orders is deflected toward sides of the pixel and optical energy from a zero order of the light is allowed to pass through the pixel, with a polarization state of the light maintained through the pixel.
FILED Wednesday, January 05, 2022
APPL NO 17/569247
ART UNIT 2871 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/003 (20130101)
G02B 5/18 (20130101)
G02B 27/4233 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/29 (20130101)
G02F 1/139 (20130101) Original (OR) Class
G02F 1/292 (20130101)
G02F 1/1313 (20130101)
G02F 1/13363 (20130101)
G02F 1/13439 (20130101)
G02F 1/13471 (20130101)
G02F 1/133631 (20210101)
G02F 1/133711 (20130101)
G02F 1/133757 (20210101)
G02F 1/133788 (20130101)
G02F 2203/04 (20130101)
G02F 2203/07 (20130101)
G02F 2203/22 (20130101)
G02F 2203/24 (20130101)
G02F 2203/48 (20130101)

Pictorial Communication, e.g Television
H04N 9/3164 (20130101)
H04N 9/3167 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11966332 Reese et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Idaho Scientific LLC (Boise, Idaho)
ASSIGNEE(S) IDAHO SCIENTIFIC LLC (Boise, Idaho)
INVENTOR(S) Dale Weston Reese (Boise, Idaho);  Matthew Ryan Waltz (Boise, Idaho);  Jay Takeji Hirata (Meridian, Idaho);  Andrew James Weiler (Nampa, Idaho);  Nathan Charles Chrisman (Nampa, Idaho);  Claude Harmon Garrett, V (Meridian, Idaho)
ABSTRACT An apparatus comprising a CPU core configured to execute instructions and consume data. The apparatus includes a memory configured to store the instructions and the data. A memory protection shim is coupled to the CPU core and the memory. The memory protection shim is configured to perform transformations over digital blocks to perform at least one of authentication or decryption of the digital blocks received from the memory. The memory protection shim is coupled to the CPU core in a fashion that prevents egress of the digital blocks or ingress of other external digital blocks between the memory protection shim and the CPU core.
FILED Thursday, October 13, 2022
APPL NO 17/965762
ART UNIT 2138 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 12/0802 (20130101) Original (OR) Class
G06F 2212/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11966345 Brewer
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Micron Technology, Inc. (Boise, Idaho)
ASSIGNEE(S) Micron Technology, Inc. (Boise, Idaho)
INVENTOR(S) Tony Brewer (Plano, Texas)
ABSTRACT Implementations of the present disclosure are directed to systems and methods for reducing design complexity and critical path timing challenges of credit return logic. A wide bus supports simultaneous transmission of multiple flits, one per lane of the wide bus. A source device transmitting flits on a wide bus selects from among multiple credit return options to ensure that only one of the multiple flits being simultaneously transmitted includes a credit return value. In some example embodiments, the receiving device checks only the flit of one lane of the wide bus (e.g., lane 0) for credit return data. In other example embodiments, the receiving device uses a bitwise-OR to combine the credit return data of all received flits in a single cycle.
FILED Tuesday, December 20, 2022
APPL NO 18/085274
ART UNIT 2184 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 13/364 (20130101) Original (OR) Class
G06F 30/3953 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11966714 Jain et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Shubham Jain (West Lafayette, Indiana);  Anand Raghunathan (West Lafayette, Indiana);  Sumeet Kumar Gupta (West Lafayette, Indiana)
ABSTRACT A circuit of cells used as a memory array and capable of in-memory arithmetic which includes a plurality of signed ternary processing, each signed ternary processing cell includes a first memory cell, adapted to hold a first digital value, a second memory cell, adapted to hold a second digital value, wherein a binary combination of the first digital value and the second digital value establishes a first signed ternary operand, a signed ternary input forming a second signed ternary operand, and a signed ternary output, wherein the signed ternary output represents a signed multiplication of the first signed ternary operand and the second signed ternary operand, a sense circuit adapted to output a subtraction result.
FILED Sunday, January 30, 2022
APPL NO 17/588311
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Electric Digital Data Processing
G06F 7/523 (20130101) Original (OR) Class
G06F 17/16 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/063 (20130101)

Static Stores
G11C 11/412 (20130101)
G11C 11/418 (20130101)
G11C 11/419 (20130101)
G11C 15/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11966776 Amarnath et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Aporva Amarnath (Ann Arbor, Michigan);  Augusto Vega (Yorktown Heights, New York);  Alper Buyuktosunoglu (Yorktown Heights, New York);  Hubertus Franke (Yorktown Heights, New York);  John-David Wellman (Yorktown Heights, New York);  Pradip Bose (Yorktown Heights, New York)
ABSTRACT Tasks of directed acyclic graphs (DAGs) may be dynamically scheduled based on a plurality of constraints and conditions, task prioritization policies, task execution estimates, and configurations of a heterogenous system. A machine learning component may be initialized to dynamically schedule the tasks of the DAGs.
FILED Wednesday, July 14, 2021
APPL NO 17/305784
ART UNIT 2196 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/485 (20130101)
G06F 9/4881 (20130101) Original (OR) Class
G06F 9/44505 (20130101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11966816 Barnes et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia)
ASSIGNEE(S) VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia)
INVENTOR(S) Edwin Barnes (Blacksburg, Virginia);  Junkai Zeng (Blacksburg, Virginia)
ABSTRACT Aspects of generating error-resistant quantum control pulses from geometrical curves are described. In some embodiments, a closed space curve is parameterized for a target gate operation of a quantum computing device. The closed space curve corresponds to an evolution operator of a time-dependent Schrödinger equation associated with the target gate operation. A control field definition is identified for the target gate operation based at least in part on a geometrical analysis of the evolution operator of the time-dependent Schrödinger equation. The target gate operation is implemented for the quantum computing device based on the control field definition.
FILED Friday, October 02, 2020
APPL NO 17/765875
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/60 (20220101) Original (OR) Class

Pulse Technique
H03K 17/92 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967064 Constance et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Morgan State University (Baltimore, Maryland)
ASSIGNEE(S) Morgan State University (Baltimore, Maryland)
INVENTOR(S) Edward Constance (Washington, District of Columbia);  Kadir Aslan (Towson, Maryland);  Enock Bonyi (Rosedale, Maryland)
ABSTRACT Systems and methods are provided for the rapid sensing of biological and environmental analytes employing a portable digital image capture device, such as a smartphone camera, to capture an image of colorimetric microwave-accelerated bioassays (“MAB”), and a digital image analyzer that processes the colorimetric signals captured by the digital camera to determine the concentration of analyte in a test sample based on a calculated pixel intensity in the captured digital image. Such systems and methods may be used to detect either a disease condition or the presence of a toxin in a particular test specimen and may generate an electronic alert that may serve to alert a medical practitioner of such disease condition or presence of a toxin so that medical intervention may be undertaken. Such electronic alert may optionally be transmitted to the user of a smartphone that captured the image, thus allowing for rapid, in-situ point-of-care analysis and detection of such conditions and immediate medical intervention.
FILED Wednesday, March 17, 2021
APPL NO 17/204194
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/31 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 7/90 (20170101)
G06T 2207/10024 (20130101)
G06T 2207/30072 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967104 Ligouri et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Anthony Ligouri (Bellbrook, Ohio);  Hayk Azatyan (Springfield, Ohio);  William Erwin (Oakwood, Ohio);  Travis Rennich (Oakwood, Ohio);  David Shald (Dayton, Ohio);  Adam Warren (Fairborn, Ohio)
ABSTRACT A method of determining the location of an object in a camera field of view is disclosed. The method may utilize a camera system that includes a digital video camera and a computer that runs image analysis software for analyzing images received from the camera. The image analysis software is configured to isolate pixel groups in each image. The method includes the steps of locating an object in the camera's field of view in which the object is represented by a set of pixels; identifying the centroid of the set of pixels representing the object; and calculating the location of the object relative to the camera based upon known parameters including the focal plane and camera lens location.
FILED Monday, November 29, 2021
APPL NO 17/536176
ART UNIT 2486 — Recording and Compression
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/73 (20170101) Original (OR) Class

Image or Video Recognition or Understanding
G06V 20/17 (20220101)

Pictorial Communication, e.g Television
H04N 7/183 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967247 Hargrove et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) Rehabilitation Institute of Chicago (Chicago, Illinois)
ASSIGNEE(S) Rehabilitation Institute of Chicago (Chicago, Illinois)
INVENTOR(S) Levi J. Hargrove (Chicago, Illinois);  Richard B. Woodward (Chicago, Illinois)
ABSTRACT An apparatus comprising an arm band and an electromyographic (EMG) control module is disclosed. The apparatus includes an electromygraphic (EMG) control module configured to receive EMG information generated by an individual; identify a gesture class based on the EMG information, and train using the received EMG information and the gesture class. The gesture class corresponds to an intended gesture made by the individual.
FILED Monday, October 05, 2020
APPL NO 17/063217
ART UNIT 2629 — Recording and Compression
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/296 (20210101)
A61B 5/389 (20210101)
A61B 5/681 (20130101)
A61B 5/6811 (20130101)
A61B 5/6824 (20130101)
A61B 5/7405 (20130101)

Electric Digital Data Processing
G06F 3/017 (20130101)

Image Data Processing or Generation, in General
G06T 19/003 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 19/003 (20130101) Original (OR) Class

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967410 Blakely et al.
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
APPLICANT(S) Meso Scale Technologies, LLC. (Rockville, Maryland);  THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland)
ASSIGNEE(S) Meso Scale Technologies, LLC (Rockville, Maryland);  THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland)
INVENTOR(S) William F Blakely (Silver Spring, Maryland);  Eli N. Glezer (Del Mar, California);  John Kenten (Boyds, Maryland);  Sudeep Kumar (Gaithersburg, Maryland);  Anu Mathew (North Potomac, Maryland);  Natalia I. Ossetrova (Silver Spring, Maryland);  George Sigal (Rockville, Maryland)
ABSTRACT Methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. Also, algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.
FILED Thursday, February 22, 2018
APPL NO 15/902597
ART UNIT 1678 — Recording and Compression
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/3273 (20130101)
G01N 33/6893 (20130101)
G01N 35/00 (20130101)
G01N 2333/70535 (20130101)
G01N 2333/70578 (20130101)
G01N 2800/40 (20130101)
G01N 2800/60 (20130101)

Measurement of Nuclear or X-radiation
G01T 1/00 (20130101)
G01T 1/02 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 20/40 (20180101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967495 Christian
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Leidoc, Inc. (Reston, Virginia)
ASSIGNEE(S) Leidos, Inc. (Reston, Virginia)
INVENTOR(S) Noah Peter Christian (San Diego, California)
ABSTRACT A low power mass spectrometer assembly includes at least an ionization component, an electrostatic analyzer, a lens assembly, a magnet assembly and at least one detector located in a same plane as the entrance to the magnet assembly for detecting the deflected sample ions and/or fragments of sample ions, including ions or ion fragments indicative of the Vitamin D metabolite within the sample.
FILED Tuesday, December 07, 2021
APPL NO 17/544599
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/004 (20130101) Original (OR) Class
H01J 49/0013 (20130101)
H01J 49/16 (20130101)
H01J 49/20 (20130101)
H01J 49/24 (20130101)
H01J 49/025 (20130101)
H01J 49/30 (20130101)
H01J 49/067 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967619 Shinohara et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Teledyne Scientific and Imaging, LLC (Thousand Oaks, California)
ASSIGNEE(S) TELEDYNE SCIENTIFIC and IMAGING, LLC (Thousand Oaks, California)
INVENTOR(S) Keisuke Shinohara (Thousand Oaks, California);  Casey King (Newbury Park, California);  Eric Regan (Moorpark, California);  Miguel Urteaga (Moorpark, California)
ABSTRACT Laterally-gated transistors and lateral Schottky diodes are disclosed. The FET includes a substrate, source and drain electrodes, channel, a gate electrode structure, and a dielectric layer. The gate electrode structure includes an electrode in contact with the channel and a lateral field plate adjacent to the electrode. The dielectric layer is disposed between the lateral field plate and the channel. The lateral field plate contacts the dielectric layer and to modulate an electric field proximal to the gate electrode proximal to the drain or source electrodes. Also disclosed is a gate electrode structure with lateral field plates symmetrically disposed relative to the gate electrode. Also disclosed in a substrate with dielectric structures buried in the substrate remote from the gate electrode structure. A lateral Schottky diode having an anode structure includes an anode (A), cathodes (C) and lateral field plates located between the anode and the cathodes.
FILED Wednesday, September 16, 2020
APPL NO 17/022521
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/404 (20130101) Original (OR) Class
H01L 29/778 (20130101)
H01L 29/872 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967678 Lin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) SOLID ENERGIES INC. (Garden Grove, California)
ASSIGNEE(S) Solid Energies, Inc. (Anaheim, California)
INVENTOR(S) Zhigang Lin (Garden Grove, California);  Chunhu Tan (Garden Grove, California);  Tianyu Meng (Garden Grove, California)
ABSTRACT Electrolyte-infiltrated composite electrode includes an electrolyte component consisting of a polymer matrix with ceramic nanoparticles embedded in the matrix to form a networking structure of electrolyte. Suitable ceramic nanoparticles have the basic formula Li7La3Zr2O12 (LLZO) and its derivatives such as AlxLi7-xLa3Zr2-y-zTayNbzO12 where x ranges from 0 to 0.85, y ranges from 0 to 0.50 and z ranges from 0 to 0.75, wherein at least one of x, y and z is not equal to 0. The networking structure of the electrolyte establishes an effective lithium-ion transport pathway in the electrode and strengthens the contact between electrode layer and solid-state electrolyte resulting in higher lithium-ion electrochemical cell's cycling stability and longer battery life. Sold-state electrolytes incorporating the ceramic particles demonstrate improved performance. Large dimensional electrolyte-infiltrated composite electrode sheets can be used in all solid-state lithium electrochemical pouch cells which can be assembled into battery packs.
FILED Monday, January 16, 2023
APPL NO 18/097384
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 4/622 (20130101)
H01M 4/625 (20130101)
H01M 10/0525 (20130101)
H01M 10/0562 (20130101) Original (OR) Class
H01M 2004/021 (20130101)
H01M 2300/0071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967738 Bernhardt
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Roger D. Bernhardt (St. Charles, Missouri)
ABSTRACT Systems, methods, and apparatus for a full perimeter electrode cell are disclosed. In one or more embodiments, a battery comprises a plurality of battery cells. The battery further comprises a plurality of anode electrodes and a plurality of cathode electrodes, of each of the battery cells, arranged around a perimeter of the battery. In at least one embodiment, the anode electrodes and the cathode electrodes, of each of the battery cells, are arranged such that they are alternating around the perimeter of the battery. In some embodiments, there are an equal number of the anode electrodes and the cathode electrodes, for each of the battery cells.
FILED Thursday, November 14, 2019
APPL NO 16/684442
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0436 (20130101)
H01M 10/0585 (20130101)
H01M 50/54 (20210101)
H01M 50/105 (20210101)
H01M 50/531 (20210101) Original (OR) Class
H01M 50/533 (20210101)
H01M 50/547 (20210101)
H01M 50/557 (20210101)
H01M 2220/20 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 60/10 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967849 Temkin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Sea Systems Command (NAVSEA)
Johns Hopkins University Applied Physics Laboratory (JH APL)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, North Dakota)
INVENTOR(S) Deanna K. Temkin (Silver Spring, Maryland);  Tyler J. Boehmer (Columbia, Maryland)
ABSTRACT An active filter system for filtering power on a power system may include a converter, an energy storage device, and control circuitry. The converter may be configured to be electrically coupled to a power source at a converter input and an active filter system bus at a converter output. The converter may be configured to deliver power to the active filter system bus that serves a dynamic load. The energy storage device may be electrically coupled to the active filter system bus and configured to filter the power via charge and discharge of an energy storage device. The control circuitry may be configured to control the converter to condition power drawn from the power source to create a filtered load based on programmable active filter controls. The programmable active filter controls may be based on a measurement of a load current being supplied to the dynamic load and a state of charge of the energy storage device.
FILED Tuesday, August 31, 2021
APPL NO 17/462951
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 4/00 (20130101)
H02J 7/0063 (20130101) Original (OR) Class
H02J 7/007182 (20200101)
H02J 2207/10 (20200101)
H02J 2207/20 (20200101)
H02J 2207/40 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967853 Hanson, Jr.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (, None)
INVENTOR(S) Jeffrey S Hanson, Jr. (South Kingstown, Rhode Island)
ABSTRACT An autonomous underwater vehicle includes a vehicle body controlled by a processor. An anchor joined to a tether is disposed in the vehicle. The vehicle has control surfaces for maneuvering, a propulsion unit, and a turbine. The propulsion unit and turbine generate thrust to propel the vehicle. A power source provides power to the vehicle. The turbine is further joined to a generator. When the processor detects that the power source is below a threshold value, the propulsion unit is stopped, the anchor is deployed, and the control surfaces are operated to move the vehicle in a predetermined trajectory through a fluid stream of the environment restrained by the tether. The fluid stream causes rotation of the turbine and generator to recharge the power source.
FILED Friday, April 16, 2021
APPL NO 17/232477
ART UNIT 2859 — Printing/Measuring and Testing
CURRENT CPC
Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers
B63G 8/001 (20130101)
B63G 8/08 (20130101)
B63G 2008/004 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/1415 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967882 Fleury et al.
FUNDED BY
Department of Defense (DOD)
United States Special Operations Command (SOCOM)
APPLICANT(S) Apptronik, Inc. (Austin, Texas)
ASSIGNEE(S) Apptronik, Inc. (Austin, Texas)
INVENTOR(S) Paul Gloninger Fleury (Austin, Texas);  Nicholas Arden Paine (Austin, Texas);  Jonas Alexan Fox (Austin, Texas)
ABSTRACT A radial stacked actuator includes an actuator ground; a motor including a motor ground constrained to the actuator ground with one or more rotational degrees of freedom; a spring coupled between the motor ground and the actuator ground; a gearbox coupled to the motor at an input of the gearbox; and an actuator output coupled to an output of the gearbox. The spring is configured to deflect as the motor ground rotates relative to the actuator ground.
FILED Wednesday, December 07, 2022
APPL NO 18/254116
ART UNIT 3658 — Material and Article Handling
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/126 (20130101)
B25J 9/1025 (20130101)

Dynamo-electric Machines
H02K 7/116 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11968176 Hartley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Layered Sensing Exploitation Division (AFRL/RYA)
APPLICANT(S) ARCHITECTURE TECHNOLOGY CORPORATION (Eden Prairie, Minnesota)
ASSIGNEE(S)
INVENTOR(S) Timothy E. Hartley (Eden Prairie, Minnesota);  Ranga S. Ramanujan (Medina, Minnesota);  Clint M. Sanders (Plymouth, Minnesota)
ABSTRACT Embodiments for a method of implementing multiple domains in a network switching device are disclosed. The method includes assigning a plurality of hardware ports to a plurality of domains. Ports are assigned to at least two of the plurality of domains, and none of the ports are concurrently assigned to multiple domains. The method also includes loading rules for forwarding packets between the plurality of ports into a data plane. The rules direct the data plane to forward only between ports in a common domain of the plurality of domains. The method also includes assuring that a packet received at any port assigned to a first domain is not sent in legible form from any port assigned to a second domain if an error causes the data plane to forward or request forwarding the packet to any port assigned to a second domain.
FILED Wednesday, July 27, 2022
APPL NO 17/815329
ART UNIT 2425 — Cable and Television
CURRENT CPC
Electric Digital Data Processing
G06F 9/45558 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 12/4641 (20130101)
H04L 43/028 (20130101)
H04L 45/04 (20130101)
H04L 47/785 (20130101)
H04L 63/0236 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11968436 Rixman
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Communications-Electronics Research, Development and Engineering Center (CERDEC)
Night Vision and Electronic Sensors Directorate (NVESD)
Research, Development and Engineering Command (RDECOM)
APPLICANT(S) Teledyne FLIR Commercial Systems, Inc. (Goleta, California)
ASSIGNEE(S) Teledyne FLIR Commercial Systems, Inc. (Goleta, California)
INVENTOR(S) Todd E. Rixman (Goleta, California)
ABSTRACT Light weight lens barrel systems and methods are provided. In one example, an imaging device includes a lens barrel including a body and a plurality of focusing fins extending from the body. The imaging device further includes a lens system disposed within the lens barrel and configured to receive electromagnetic radiation and direct the electromagnetic radiation. The imaging device further includes a detector array including a plurality of detectors. Each of the plurality of detectors is configured to receive the electromagnetic radiation from the lens system and generate an image based on the electromagnetic radiation. Related methods and systems are also provided.
FILED Monday, December 27, 2021
APPL NO 17/562860
ART UNIT 2481 — Recording and Compression
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 7/04 (20130101)
G02B 7/021 (20130101)
G02B 13/14 (20130101)

Pictorial Communication, e.g Television
H04N 23/51 (20230101)
H04N 23/55 (20230101) Original (OR) Class
H04N 23/80 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11968905 Sun et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) NORTHEASTERN UNIVERSITY (Boston, Massachusetts)
INVENTOR(S) Nian-Xiang Sun (Winchester, Massachusetts);  Nirjhar Bhattacharjee (Cambridge, Massachusetts)
ABSTRACT A sputter growth method for a crystalline ordered topological insulator (TI) material on an amorphous substrate, which is possible to use at a CMOS-compatible temperature. The process can be integrated into CMOS fabrication processes for Spin Orbit Torque (SOT) devices. The resulting material can include a thin film crystalline ordered TI layer, sputter deposited on an amorphous substrate, and an adjacent ferromagnetic (FM) layer in which spin-orbit torque is provided by the TI layer, for example to cause switching in magnetic states in a magnetic memory device.
FILED Thursday, July 01, 2021
APPL NO 17/365779
ART UNIT 1785 — Miscellaneous Articles, Stock Material
CURRENT CPC
Static Stores
G11C 11/161 (20130101)

Electronic Memory Devices
H10B 61/00 (20230201)

Electric solid-state devices not otherwise provided for
H10N 50/01 (20230201)
H10N 50/10 (20230201) Original (OR) Class
H10N 50/80 (20230201)
H10N 50/85 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11963821 Yarmush et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
ASSIGNEE(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey)
INVENTOR(S) Martin L. Yarmush (New Brunswick, New Jersey);  Alvin Chen (New Brunswick, New Jersey);  Max Balter (New Brunswick, New Jersey);  Joshua Leipheimer (New Brunswick, New Jersey)
ABSTRACT A device and method for directing a cannula toward a target location under a patient's skin. The device is handheld and the device operations may be automated. The device includes an imaging probe for imaging the target location, a positioning unit for manipulating a cannula towards the target location, and a processor. The processor receives imaging data from the imaging probe, cannula pose data from at least one cannula position sensor, and device pose data from at least one device position sensor. The target location is identified from the imaging data, and a trajectory for manipulating the cannula towards the target location is determined based on the imaging data, the cannula pose data, and the device pose data. The processor may determine that the trajectory becomes misaligned with the target position, and may update to a corrected trajectory based on the imaging data, cannula pose data, and the device pose data.
FILED Wednesday, October 09, 2019
APPL NO 17/284018
ART UNIT 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/06 (20130101)
A61B 8/12 (20130101)
A61B 8/466 (20130101)
A61B 8/0841 (20130101) Original (OR) Class
A61B 8/4218 (20130101)
A61B 2034/2065 (20160201)
A61B 2562/0219 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964075 Huang et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
INVENTOR(S) Yong Huang (Gainesville, Florida);  Kaidong Song (Gainesville, Florida);  Ashley M. Compaan (Gainesville, Florida);  Wenxuan Chai (Gainesville, Florida)
ABSTRACT Described herein are injectable composite inks composed of a hydrogel continuous phase with a plurality of microgels present within the hydrogel continuous phase. The inks described herein have unique chemical and physical properties that enable them to be printed into a number of different types of articles. The articles produced by the injectable composite inks have numerous medical applications.
FILED Friday, January 15, 2021
APPL NO 17/150038
ART UNIT 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/52 (20130101) Original (OR) Class
A61L 27/222 (20130101)
A61L 27/3687 (20130101)
A61L 2400/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964242 Nair et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Sankar Nair (Atlanta, Georgia);  Shaowei Yang (Atlanta, Georgia);  Christopher W. Jones (Atlanta, Georgia);  Byunghyun Min (Atlanta, Georgia)
ABSTRACT Disclosed are methods of manufacturing a zeolite membrane, comprising: providing at least one porous substrate; and coating the at least one porous substrate with a membrane. In some embodiments, the method further comprises hydrothermally treating the membrane with a first hydrothermal treatment step with tetrapropylammonium fluoride (TPAF) and a second hydrothermal treatment step with tetraethylammonium hydroxide (TEAOH). In some embodiments, coating the substrate with a membrane comprises surrounding at least a portion of the at least one porous substrate with a precursor gel, the gel comprising a gel phase and a plurality of CHA or MFI crystals; heating the at least one porous substrate and the precursor gel; washing the at least one porous substrate; drying the at least one porous substrate; and calcining the at least one porous substrate.
FILED Thursday, April 09, 2020
APPL NO 17/602490
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/228 (20130101)
B01D 69/12 (20130101)
B01D 71/028 (20130101) Original (OR) Class
B01D 2257/504 (20130101)
B01D 2257/702 (20130101)
B01D 2323/08 (20130101)
B01D 2323/10 (20130101)
B01D 2325/02 (20130101)
B01D 2325/04 (20130101)
B01D 2325/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964257 Zhou et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) University of Wyoming (Laramie, Wyoming)
ASSIGNEE(S) UNIVERSITY OF WYOMING (Laramie, Wyoming)
INVENTOR(S) Jing Zhou (Laramie, Wyoming);  Joseph Holles (Laramie, Wyoming);  Richard Horner (Laramie, Wyoming);  Jintao Miao (Laramie, Wyoming)
ABSTRACT Provided herein are catalyst materials and processes for processing hydrocarbons. For example, doped ceria-supported metal catalysts are provided exhibiting good activity and stability for commercially relevant DRM process conditions including low temperature and long term operation.
FILED Wednesday, October 28, 2020
APPL NO 17/082406
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/10 (20130101) Original (OR) Class
B01J 23/755 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 3/40 (20130101)
C01B 32/40 (20170801)
C01B 2203/061 (20130101)
C01B 2203/0227 (20130101)
C01B 2203/0277 (20130101)
C01B 2203/0283 (20130101)
C01B 2203/1058 (20130101)
C01B 2203/1082 (20130101)
C01B 2203/1241 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964384 Jiang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Hanqing Jiang (Chandler, Arizona);  Zirui Zhai (Tempe, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Hanqing Jiang (Chandler, Arizona);  Zirui Zhai (Tempe, Arizona)
ABSTRACT A curved origami-based metamaterial includes a panel of material having a plurality of curved creases each disposed within a plane of the panel. The panel is configured to be folded along one of the plurality of creases, and the panel is also configured to be bent about an axis disposed outside the plane of the panel. Stiffness manipulation is configured to be achieved in situ by activating a different one of the plurality of curved creases.
FILED Wednesday, September 29, 2021
APPL NO 17/449351
ART UNIT 3617 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 15/0033 (20130101) Original (OR) Class

Ships or Other Waterborne Vessels; Equipment for Shipping
B63B 5/00 (20130101)
B63B 35/00 (20130101)
B63B 2231/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964387 Rucker et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Tennessee Research Foundation (Knoxville, Tennessee);  Hunter Bryant Gilbert (Baton Rouge, Louisiana)
ASSIGNEE(S) University of Tennessee Research Foundation (Knoxville, Tennessee);  Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S) Daniel Caleb Rucker (Knoxville, Tennessee);  Hunter Bryant Gilbert (Baton Rouge, Louisiana)
ABSTRACT A concentric tube steerable device includes a plurality of tubes having a nested, concentric configuration. The tubes include an outer tube and an inner tube that extends coaxially within the outer tube. The inner tube terminates at a tip, and a pose of the tip is effectuated through individual or collective rotation or translation of the tubes about a tube axis. The concentric tube steerable device includes an actuator for rotating at least one tube about a respective tube axis, and a translator for translating at least one tube along a respective tube axis. Each tube includes a precurved portion and a corresponding axis of precurvature. For at least one tube, a flexural rigidity of the tube along its axis of precurvature is less than a flexural rigidity of the tube along a second axis that is perpendicular to the axis of precurvature, thereby improving stability of the tube.
FILED Friday, June 24, 2022
APPL NO 17/848970
ART UNIT 3656 — Material and Article Handling
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/00234 (20130101)
A61B 34/30 (20160201)
A61B 34/70 (20160201)
A61B 2017/00309 (20130101)
A61B 2017/00331 (20130101)
A61B 2017/00991 (20130101)
A61B 2034/301 (20160201)

Manipulators; Chambers Provided With Manipulation Devices
B25J 18/002 (20130101)
B25J 18/04 (20130101)
B25J 18/005 (20130101)
B25J 18/06 (20130101) Original (OR) Class
B25J 18/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964884 Li et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa)
INVENTOR(S) Wenzhen Li (Ames, Iowa);  Hengzhou Liu (Ames, Iowa);  Yifu Chen (Ames, Iowa)
ABSTRACT The present application relates to a system for removal of nitrate from water. The system includes a first reactor comprising a porous oxide-derived silver electrode (OD-Ag) for electrocatalytic reduction of nitrate (NO3) to nitrite (NO2) and a second reactor comprising a Pd-based catalyst for catalytic reduction of nitrite (NO2). Also disclosed is a method of removing nitrate from water.
FILED Monday, March 08, 2021
APPL NO 17/195321
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Separation
B01D 53/18 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 21/50 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/42 (20130101)
C02F 1/70 (20130101)
C02F 1/4676 (20130101) Original (OR) Class
C02F 1/46109 (20130101)
C02F 2001/422 (20130101)
C02F 2001/46133 (20130101)
C02F 2101/163 (20130101)
C02F 2103/007 (20130101)
C02F 2201/46115 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/8624 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964885 Choi et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Kyoung-Shin Choi (Fitchburg, Wisconsin);  Dohwan Nam (Madison, Wisconsin)
ABSTRACT Tandem electrodialysis (ED) cell systems and methods for using the tandem ED cell systems to extract and recover ions from ion-containing solutions are provided. The tandem ED cell systems are composed of ion-extraction and ion-recovery ED cells. A redox couple contained in the anolyte of the ion-extraction ED cell is different from a redox couple contained in the catholyte of the ion-extraction ED cell. The electrode reactions in the ion-extraction ED cell are reversed in the ion-recovery ED cell, with the anolyte and catholyte of the two ED cells swapped and continuously circulated. As a result, the redox species in the anolyte and catholyte of the two cells are never depleted, which allows for achieving ion extraction and ion recovery with the use of a minimal amount of the redox couples.
FILED Wednesday, February 10, 2021
APPL NO 17/172558
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 61/48 (20130101)
B01D 2255/20723 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/4695 (20130101) Original (OR) Class
C02F 2103/08 (20130101)
C02F 2201/46 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964920 Watkins et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) James J. Watkins (South Hadley, Massachusetts);  Dong-Po Song (Rizhao, China PRC);  Wenhao Li (Sunderland, Massachusetts)
ABSTRACT Various embodiments disclosed relate to a method of forming a composite including a carbon composite structure. The method includes disposing a precursor composition on a substrate. The composition includes a porogen component, a carbon component, and a catalyst component. The method further includes irradiating the precursor composition to form the carbon composite structure.
FILED Friday, August 18, 2017
APPL NO 16/326069
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 3/06 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 70/00 (20130101)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/83 (20130101)
C04B 35/524 (20130101)
C04B 35/528 (20130101)
C04B 35/532 (20130101)
C04B 38/02 (20130101)
C04B 38/0022 (20130101) Original (OR) Class
C04B 2111/0081 (20130101)
C04B 2111/00853 (20130101)
C04B 2235/5264 (20130101)
C04B 2235/5454 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/043 (20130101)
H01M 4/049 (20130101)
H01M 4/133 (20130101)
H01M 4/0471 (20130101)
H01M 4/587 (20130101)
H01M 4/1393 (20130101)
H01M 6/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965068 Dichtel et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) William R. Dichtel (Wilmette, Illinois);  Deepti Gopalakrishnan (Ithaca, New York)
ABSTRACT Cross-linked polymer networks that are at least partially conjugated (e.g., phenylene vinylene polymer networks). The cross-linked polymer networks may be thin-films disposed on a substrate. The cross-linked polymer network may be covalently bonded to the substrate. The cross-linked polymer networks can be used, for example, in methods of detecting explosives (e.g., RDX (cyclotrimethylenetrinitramine)) and degradation products thereof.
FILED Thursday, August 20, 2020
APPL NO 16/998987
ART UNIT 1796 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/18 (20130101) Original (OR) Class
C08J 2325/08 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101)
C09K 2211/1425 (20130101)
C09K 2211/1466 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101)
G01N 33/0057 (20130101)
G01N 2021/6432 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965164 Chilkoti et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Ashutosh Chilkoti (Durham, North Carolina);  Stefan Zauscher (Durham, North Carolina);  Lei Tang (Durham, North Carolina);  Sonal Deshpande (Durham, North Carolina)
ABSTRACT Compositions and methods disclosed herein can help provide improved delivery of non-natural therapeutic nucleotides for the treatment of diseases such as cancer. An example composition includes an assembly of amphiphilic polynucleotides, where each amphiphilic polynucleotide includes an aptamer portion, a first nucleotide portion, and a second nucleotide portion.
FILED Monday, October 31, 2022
APPL NO 18/051487
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7105 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 15/115 (20130101)
C12N 2310/16 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965190 Kaznessis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Yiannis John Kaznessis (New Brighton, Minnesota);  Seth Ritter (Minneapolis, Minnesota);  Benjamin Hackel (Edina, Minnesota)
ABSTRACT Provided herein are a vector, a genetically modified bacterium including the vector, methods of making the bacterium, methods of using the bacterium, and kits including the bacterium. The vector includes a coding region encoding at least one antimicrobial peptide, and the antimicrobial peptide includes at least one lysin.
FILED Friday, September 07, 2018
APPL NO 16/645281
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/747 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)
C12N 9/2462 (20130101) Original (OR) Class
C12N 15/62 (20130101)
C12N 15/74 (20130101)
C12N 15/635 (20130101)
C12N 15/746 (20130101)

Enzymes
C12Y 302/01017 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965831 Gopinath et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, a Body Corporate (Denver, Colorado)
INVENTOR(S) Juliet T. Gopinath (Boulder, Colorado);  Brendan M. Heffernan (Boulder, Colorado);  Robert Niederriter (Los Angeles, California);  Stephanie A. Meyer (Denver, Colorado);  Diego Restrepo (Littleton, Colorado);  Emily A. Gibson (Boulder, Colorado);  Mark E. Siemens (Denver, Colorado)
ABSTRACT Sub-diffraction limited fluorescent images using a fiber-based stimulated emission depletion (STED) microscope are reported. Both excitation and depletion beams are transported through polarization-maintaining fiber and a lateral resolution of 100 nm has been achieved.
FILED Friday, March 01, 2019
APPL NO 16/976946
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101) Original (OR) Class
G01N 2021/6484 (20130101)

Optical Elements, Systems, or Apparatus
G02B 3/0087 (20130101)
G02B 21/0032 (20130101)
G02B 21/0068 (20130101)
G02B 21/0076 (20130101)
G02B 27/58 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965869 Urschel et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
ASSIGNEE(S)
INVENTOR(S) Matthew R. Urschel (Troy, New York);  Andrew Turk (Troy, New York);  Tessa Hilary Pocock (Troy, New York)
ABSTRACT An apparatus for remote detection of plant growth dynamics is described. The apparatus includes an excitation LED (light emitting diode) module, a detection module and a controller module coupled to the excitation LED module and the detection module. The excitation LED module includes at least one LED. Each LED is configured to emit an excitation light in response to an excitation control signal. The excitation light has an emitted light spectrum. The detection module includes a photodetector configured to detect an initial chlorophyll a fluorescence (“ChlF”) light and an excited ChlF light from a plant species. The photodetector is further configured to convert the detected initial ChlF light into an initial detection electrical signal and the detected excited ChlF light into an excited detection electrical signal. The excited ChlF light is emitted from the plant species in response to receiving the excitation light. The controller module is configured to provide the excitation control signal to the excitation module, to capture the initial and excited detection electrical signals from the detection module and to determine chlorophyll fluorescence data based, at least in part, on the initial and excited detection electrical signals. The excitation LED module and the detection module are configured to be positioned remotely from the plant species. The chlorophyll fluorescence data represents a growth characteristic of the plant species.
FILED Wednesday, September 14, 2022
APPL NO 17/944569
ART UNIT 2878 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/64 (20130101)
G01N 33/0098 (20130101) Original (OR) Class
G01N 2201/062 (20130101)
G01N 2201/0696 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965881 Motamedi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Science Foundation (NSF)
APPLICANT(S) The Board of Regents of The University of Texas System (Austin, Texas);  Kansas State University Research Foundation (Manhattan, Kansas)
ASSIGNEE(S) Kansas State University Research Foundation (Manhattan, Kansas);  Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S) Massoud Motamedi (Houston, Texas);  Allan R. Brasier (Galveston, Texas);  Stefan H. Bossmann (Manhattan, Kansas);  Christopher T. Culbertson (Manhattan, Kansas);  Deryl Troyer (Manhattan, Kansas)
ABSTRACT Methods and devices for microfluidic detection of a biological maker in a biospecimen collected from a subject are disclosed. The microfluidic devices include nanoparticle-based nanosensors comprising supramolecular recognition sequences, protease consensus sequences, post-translationally modifiable sequences, or sterically hindered benzylether bonds for specific interaction with a biological marker. Also disclosed are particular nanosensors for detecting cytokines, and other proteins based upon supramolecular recognition without chemical modification or enzymatic cleavage.
FILED Friday, March 24, 2017
APPL NO 16/088407
ART UNIT 1678 — Optics
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 2300/0636 (20130101)
B01L 2300/0816 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/574 (20130101)
G01N 33/54346 (20130101) Original (OR) Class
G01N 2333/70596 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965967 Che et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
Department of Transportation (USDOT)
APPLICANT(S) Oregon State University (Corvallis, Oregon)
ASSIGNEE(S) Oregon State University (Corvallis, Oregon)
INVENTOR(S) Erzhuo Che (Corvallis, Oregon);  Michael Olsen (Corvallis, Oregon)
ABSTRACT A computer implemented scheme for a light detection and ranging (LIDAR) system where point cloud feature extraction and segmentation by efficiently is achieved by: (1) data structuring; (2) edge detection; and (3) region growing.
FILED Wednesday, November 16, 2022
APPL NO 18/056247
ART UNIT 2488 — Recording and Compression
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/4804 (20130101)
G01S 17/89 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/13 (20170101)
G06T 7/136 (20170101)
G06T 7/174 (20170101)
G06T 7/187 (20170101)
G06T 2207/10028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11966159 Meyers et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Inpria Corporation (Corvallis, Oregon)
ASSIGNEE(S) Inpria Corporation (Corvallis, Oregon)
INVENTOR(S) Stephen T. Meyers (Corvallis, Oregon);  Douglas A. Keszler (Corvallis, Oregon);  Kai Jiang (Corvallis, Oregon);  Jeremy T. Anderson (Corvallis, Oregon);  Andrew Grenville (Corvallis, Oregon)
ABSTRACT Organometallic solutions have been found to provide high resolution radiation based patterning using thin coatings. The patterning can involve irradiation of the coated surface with a selected pattern and developing the pattern with a developing agent to form the developed image. The patternable coatings may be susceptible to positive-tone patterning or negative-tone patterning based on the use of an organic developing agent or an aqueous acid or base developing agent. The radiation sensitive coatings can comprise a metal oxo/hydroxo network with organic ligands. A precursor solution can comprise an organic liquid and metal polynuclear oxo-hydroxo cations with organic ligands having metal carbon bonds and/or metal carboxylate bonds.
FILED Tuesday, September 06, 2022
APPL NO 17/903605
ART UNIT 1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/09 (20130101)
G03F 7/20 (20130101)
G03F 7/30 (20130101)
G03F 7/32 (20130101)
G03F 7/0042 (20130101) Original (OR) Class
G03F 7/0043 (20130101)
G03F 7/322 (20130101)
G03F 7/325 (20130101)
G03F 7/2002 (20130101)
G03F 7/2037 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967629 Das et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Kansas State University Research Foundation (Manhattan, Kansas);  Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Kansas State University Research Foundation (Manhattan, Kansas);  Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Suprem R. Das (Manhattan, Kansas);  David B. Janes (West Lafayette, Indiana);  Jiseok Kwon (Lafayette, Indiana)
ABSTRACT A semiconductor device and methods of fabricating and using the same are provided. The semiconductor device comprises a channel region and at least a first, second, and third electrode. The channel region includes a compound having a transition metal and a chalcogen. The thickness of the channel region is about 3 to about 40 atomic layers.
FILED Saturday, June 22, 2019
APPL NO 17/253180
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02568 (20130101)
H01L 29/24 (20130101)
H01L 29/435 (20130101) Original (OR) Class
H01L 29/7606 (20130101)
H01L 29/66969 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11968073 Mohammadnezhad et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Hossein Mohammadnezhad (Irvine, California);  Huan Wang (Irvine, California);  Payam Heydari (Irvine, California)
ABSTRACT Aspects of quadrature phase shift keying for quadrature amplitude modulation are described. In some examples, quadrature phase shift keying signals are generated using quadrature phase shift keying modulators. The quadrature phase shift keying signals are combined in a combiner circuit to generate a quadrature amplitude modulation signal for wireless transmission.
FILED Wednesday, June 17, 2020
APPL NO 17/597261
ART UNIT 2631 — Digital Communications
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/361 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11968848 Han et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Seunghoon Han (Seoul, South Korea);  Kwanghee Lee (Hwaseong-si, South Korea);  Yongwan Jin (Seoul, South Korea);  Yongsung Kim (Suwon-si, South Korea);  Changgyun Shin (Anyang-si, South Korea);  Jeongyub Lee (Yongin-si, South Korea);  Amir Arbabi (Pasadena, California);  Andrei Faraon (Pasadena, California);  Yu Horie (Pasadena, California)
ABSTRACT An image sensor includes a first light sensor layer including light sensing cells configured to sense first light of an incident light and generate electrical signals based on the sensed first light, and a color filter array layer disposed on the first light sensor layer, and including color filters respectively facing the light sensing cells. The image sensor further includes a second light sensor layer disposed on the color filter array layer, and configured to sense second light of the incident light and generate an electrical signal based on the sensed second light. Each of the color filters includes a nanostructure including a first material having a first refractive index, and a second material having a second refractive index greater than the first refractive index, the first material and the second material being alternately disposed with a period.
FILED Thursday, October 15, 2020
APPL NO 17/071364
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/14621 (20130101)
H01L 27/14636 (20130101)
H01L 27/14645 (20130101)

Organic electric solid-state devices
H10K 39/32 (20230201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11964242 Nair et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Sankar Nair (Atlanta, Georgia);  Shaowei Yang (Atlanta, Georgia);  Christopher W. Jones (Atlanta, Georgia);  Byunghyun Min (Atlanta, Georgia)
ABSTRACT Disclosed are methods of manufacturing a zeolite membrane, comprising: providing at least one porous substrate; and coating the at least one porous substrate with a membrane. In some embodiments, the method further comprises hydrothermally treating the membrane with a first hydrothermal treatment step with tetrapropylammonium fluoride (TPAF) and a second hydrothermal treatment step with tetraethylammonium hydroxide (TEAOH). In some embodiments, coating the substrate with a membrane comprises surrounding at least a portion of the at least one porous substrate with a precursor gel, the gel comprising a gel phase and a plurality of CHA or MFI crystals; heating the at least one porous substrate and the precursor gel; washing the at least one porous substrate; drying the at least one porous substrate; and calcining the at least one porous substrate.
FILED Thursday, April 09, 2020
APPL NO 17/602490
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/228 (20130101)
B01D 69/12 (20130101)
B01D 71/028 (20130101) Original (OR) Class
B01D 2257/504 (20130101)
B01D 2257/702 (20130101)
B01D 2323/08 (20130101)
B01D 2323/10 (20130101)
B01D 2325/02 (20130101)
B01D 2325/04 (20130101)
B01D 2325/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964304 Kumar et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Sortera Alloys, Inc. (Forth Worth, Texas)
ASSIGNEE(S) Sortera Technologies, Inc. (Markle, Indiana)
INVENTOR(S) Nalin Kumar (Fort Worth, Texas);  Manuel Gerardo Garcia, Jr. (Lexington, Kentucky);  Isha Kamleshbhai Maun (Arlington, Texas)
ABSTRACT A material sorting system sorts materials utilizing an x-ray fluorescence and/or a vision system that implements a machine learning system in order to identify or classify each of the materials, which are then sorted into separate groups based on such an identification or classification determining that the materials are composed of either wrought aluminum, extruded aluminum, or cast aluminum. The system is capable of sorting between cast aluminum alloys and also between wrought aluminum alloys.
FILED Friday, April 09, 2021
APPL NO 17/227245
ART UNIT 3653 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking
B07C 5/04 (20130101)
B07C 5/34 (20130101)
B07C 5/342 (20130101)
B07C 5/3422 (20130101) Original (OR) Class
B07C 2501/0054 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964918 Petrie et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Christian M. Petrie (Oak Ridge, Tennessee);  Brian C. Jolly (Oak Ridge, Tennessee);  Kurt A. Terrani (Oak Ridge, Tennessee);  Michael P. Trammell (Oak Ridge, Tennessee)
ABSTRACT An improved method for embedding one or more sensors in SiC is provided. The method includes depositing a binder onto successive layers of a SiC powder feedstock to produce a dimensionally stable green body have a true-sized cavity. A sensor component is then press-fit into the true-sized cavity. Alternatively, the green body is printed around the sensor component. The assembly (the green body and the sensor component) is heated within a chemical vapor infiltration (CVI) chamber for debinding, and a precursor gas is introduced for densifying the SiC matrix material. During infiltration, the sensor component becomes bonded to the densified SiC matrix, the sensor component being selected to be thermodynamically compatible with CVI byproducts at elevated temperatures, including temperatures in excess of 1000° C.
FILED Wednesday, January 06, 2021
APPL NO 17/142315
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/63 (20130101)
C04B 35/565 (20130101)
C04B 37/021 (20130101) Original (OR) Class
C04B 37/042 (20130101)
C04B 2235/3826 (20130101)
C04B 2235/6026 (20130101)
C04B 2237/62 (20130101)
C04B 2237/365 (20130101)
C04B 2237/403 (20130101)
C04B 2237/408 (20130101)

Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 11/245 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964994 Beard et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  University of Utah Research Foundation (Salt Lake City, Utah);  Duke University (Durham, North Carolina)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Duke University (Durham, North Carolina)
INVENTOR(S) Matthew C. Beard (Arvada, Colorado);  Haipeng Lu (Lakewood, Colorado);  Annalise Elizabeth Maughan (Arvada, Colorado);  Joseph Jonathan Berry (Boulder, Colorado);  Zeev Valentine Vardeny (Salt Lake City, Utah);  Chuanxiao Xiao (Lakewood, Colorado);  Volker Wolfgang Blum (Durham, North Carolina);  David Brian Mitzi (Hillsborough, North Carolina)
ABSTRACT The present disclosure relates to a composition that includes a perovskite of A2BX4, where A includes an R-form of a chiral molecule of at least one of
and/or an S-form of the chiral molecule, B includes a cation, X includes an anion, R1 includes a first carbon chain having between 2 and 5 carbon atoms, R2 includes at least one of a hydrogen atom, a halogen atom, a carboxylic acid group, an alkoxy group, and/or a second carbon chain, and R3 includes a third carbon chain.
FILED Wednesday, December 02, 2020
APPL NO 17/109668
ART UNIT 1785 — Miscellaneous Articles, Stock Material
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 211/65 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/24 (20130101) Original (OR) Class
C07F 7/2208 (20130101)

Organic electric solid-state devices
H10K 10/50 (20230201)
H10K 85/50 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964995 Zhu et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Brown University Technology Ventures Office (Providence, Rhode Island)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Brown University (Providence, Rhode Island)
INVENTOR(S) Kai Zhu (Littleton, Colorado);  Jinhui Tong (Wuhan, China PRC);  Yuanyuan Zhou (Hong Kong, China Hong Kong);  Nitin P. Padture (Providence, Rhode Island);  Jue Gong (Chengdu, China PRC)
ABSTRACT The present disclosure relates to a composition that includes a perovskite having a stoichiometry comprising A1-xFAxSn1-yBy(I1-zXz)3, where A is a first cation, B is a second cation, X is a halide, and 0.5≤x≤0.9, 0.5≤y≤0.9, and 0≤z≤1. In some embodiments of the present disclosure, A may include at least one of cesium, guanidinium, and/or methylammonium. In some embodiments of the present disclosure, X may include at least one of bromide and/or chloride. In some embodiments of the present disclosure, z may be equal to zero.
FILED Thursday, January 27, 2022
APPL NO 17/586069
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/24 (20130101) Original (OR) Class

Organic electric solid-state devices
H10K 30/10 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965074 Strasser et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Office of Science (DOE-SC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Giner, Inc. (Newton, Massachusetts)
ASSIGNEE(S) GINER, INC. (Newton, Massachusetts)
INVENTOR(S) Derek J. Strasser (Marlborough, Massachusetts);  Hui Xu (Acton, Massachusetts);  Judith Lattimer (Cambridge, Massachusetts)
ABSTRACT Anion exchange membrane and methods of making and using the same. In one embodiment, the anion exchange membrane may be made by a method that includes a two-step polymerization. In the first step, an α-olefin monomer containing a pendant halide, such as 8-bromo-1-octene, may be polymerized by Ziegler-Natta polymerization to form a first polymer portion, the first polymer portion being a homopolymer. In the second step, the polymerization is charged with a non-functionalized α-olefin monomer, such as ethylene, thereby forming a second polymer portion, the second polymer being a copolymer made up predominantly of the non-functionalized olefin monomer. If desired, a small amount of an α-olefin monomer containing a crosslinking functionality may be included in the first and/or second steps. Following the two-step polymerization, the polymer is fabricated into a thin film. Thereafter, the thin film may be functionalized by replacing the pendant halides with pendant cations.
FILED Thursday, June 09, 2022
APPL NO 17/836733
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 226/02 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/2231 (20130101) Original (OR) Class
C08J 2339/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965159 Choudhary et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Department of the Navy (DON)
Department of Energy (DOE)
Office of Science (DOE-SC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts);  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  The Regents of the University of California (Oakland, California)
INVENTOR(S) Amit Choudhary (Boston, Massachusetts);  Kurt Cox (Cambridge, Massachusetts);  Hari Subramanian (Oakland, California);  Elisa Franco (Oakland, California)
ABSTRACT Compositions and methods for conditionally regulating activities of CRISPR-Cas systems. In some embodiments, the methods comprise providing an inactive guide RNA comprising a regulatory domain bound by a lock nucleic acid different from the guide RNA; and displacing the lock nuclei acid from the regulatory domain by a trigger nucleic acid, thereby activating the guide RNA, wherein the activated guide RNA forms a complex with a Cas enzyme.
FILED Wednesday, January 29, 2020
APPL NO 16/776503
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/00 (20130101)
A61K 38/465 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101) Original (OR) Class
C12N 15/67 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 2310/20 (20170501)
C12N 2310/50 (20130101)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965182 Malik et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) YIELD10 BIOSCIENCE, INC. (Woburn, Massachusetts)
ASSIGNEE(S) YIELD10 BIOSCIENCE, INC. (Woburn, Massachusetts)
INVENTOR(S) Meghna Malik (Saskatoon, Canada);  Jihong Tang (West Roxbury, Massachusetts);  Kristi D. Snell (Belmont, Massachusetts)
ABSTRACT Transgenic plants having enhanced yield and having enhanced seed yield are disclosed. The transgenic plants are transformed with a transgenic polynucleotide encoding one or more metabolic enzymes. The metabolic enzymes can be from any biological source. The transgenic polynucleotide(s) comprises a nucleic acid sequences encoding the metabolic enzymes under the control of functional plant promoters, the one or more metabolic enzymes are targeted to the plastids by the addition of plastid targeting signals. Optionally the functional plant promoters are seed specific promoters and the metabolic enzymes are targeted to the plastids by the addition of plastid targeting peptide heterologous to the metabolic enzymes. Methods of making the transgenic plants and transgenic polynucleotides are disclosed. The magnitude of the increases in seed yield achieved with these transgenic plants are unprecedented.
FILED Monday, October 11, 2021
APPL NO 17/498240
ART UNIT 1663 — Plants
CURRENT CPC
Peptides
C07K 14/415 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0006 (20130101) Original (OR) Class
C12N 15/52 (20130101)
C12N 15/8243 (20130101)
C12N 15/8247 (20130101)
C12N 15/8261 (20130101)

Enzymes
C12Y 101/01082 (20130101)

Technologies for Adaptation to Climate Change
Y02A 40/146 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965197 Koffas et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Mattheos Koffas (Niskayuna, New York);  John Andrew Jones (Liberty Township, Ohio)
ABSTRACT Disclosed herein are novel microbial polycultures of two or more cell strains, capable of producing flavanones, flavonoids, and anthocyanidin-3-O-glucosides, and methods of use thereof. Also disclosed is a microbial cell capable of producing phenylpropanoic acids, and methods of use thereof.
FILED Wednesday, March 10, 2021
APPL NO 17/197468
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0006 (20130101)
C12N 9/0071 (20130101)
C12N 9/88 (20130101)
C12N 9/90 (20130101)
C12N 9/0093 (20130101)
C12N 9/93 (20130101)
C12N 9/1037 (20130101)
C12N 15/52 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/42 (20130101)
C12P 7/52 (20130101)
C12P 17/06 (20130101)
C12P 19/58 (20130101) Original (OR) Class

Enzymes
C12Y 101/01219 (20130101)
C12Y 114/11009 (20130101)
C12Y 117/01003 (20130101)
C12Y 203/01074 (20130101)
C12Y 403/01023 (20130101)
C12Y 505/01006 (20130101)
C12Y 602/01012 (20130101)
C12Y 602/01014 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965303 Miller et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) TRITON SYSTEMS, INC. (Chelmsford, Massachusetts)
ASSIGNEE(S) TRITON SYSTEMS, INC. (Chelmsford, Massachusetts)
INVENTOR(S) Zachary Miller (Nashua, New Hampshire);  William Feather (Merrimack, New Hampshire);  Nathan Krohn (Pearland, Texas);  Tyson Lawrence (Highland Ranch, Colorado);  Jihan Eljadidi (Cambridge, Maryland);  Tyler Robertson (North Attleboro, Massachusetts);  Raf Mandujano (Arlington, Maryland)
ABSTRACT Disclosed herein are a group anchor system, subsea installation tool and method of install such group anchor systems. The group anchor system includes a template through which a plurality of vertical piles, such as helical piles, are passed, drilled into the seabed at one end and secured to the template at the other to provide a mooring anchor for an offshore asset. The installation tool is a modular tool designed to mate with the group anchor system. Each module including drive mechanism for engaging and driving a pile. The piles may be driven simultaneously, individually, or in groups as required for proper placement and leveling. Methods of using the installation tool are also disclosed.
FILED Friday, June 10, 2022
APPL NO 18/251209
ART UNIT 3619 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Foundations; Excavations; Embankments; Underground or Underwater Structures
E02D 27/12 (20130101)
E02D 27/50 (20130101) Original (OR) Class
E02D 2600/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11966501 Ramanan et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Paritosh P. Ramanan (Atlanta, Georgia);  Nagi Z. Gebraeel (Marietta, Georgia)
ABSTRACT An exemplary blockchain-based decentralized computing system and method are disclosed for industrial analytics applications. The exemplary system and method leverage blockchain technology to deliver and execute privacy-preserving decentralized predictive analytics, machine learning, and optimization operations for various industrial applications using a set of self-contained analytics block smart contracts that can be readily utilized and in analytics applications to deploy across multiple sites.
FILED Friday, July 09, 2021
APPL NO 17/372064
ART UNIT 2433 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 8/41 (20130101)
G06F 11/3688 (20130101)
G06F 16/27 (20190101)
G06F 16/2379 (20190101)
G06F 21/64 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11966676 Miryala et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Fermi National Accelerator Laboratory (FNAL)
Federally Funded Research and Development Center (FFRDC)
Operated by Fermi Research Alliance, LLC (FRA) at Batavia, IL
APPLICANT(S) Fermi Research Alliance, LLC (Batavia, Illinois)
ASSIGNEE(S) Fermi Research Alliance, LLC (Batavia, Illinois)
INVENTOR(S) Sandeep Miryala (Sound Beach, New York);  James Richard Hoff (Wheaton, Illinois);  Grzegorz W. Deptuch (Great Neck, New York)
ABSTRACT A soft error-mitigating semiconductor design system and associated methods that tailor circuit design steps to mitigate corruption of data in storage elements (e.g., flip flops) due to Single Events Effects (SEEs). Required storage elements are automatically mapped to triplicated redundant nodes controlled by a voting element that enforces majority-voting logic for fault-free output (i.e., Triple Modular Redundancy (TMR)). Storage elements are also optimally positioned for placement in keeping with SEE-tolerant spacing constraints. Additionally, clock delay insertion (employing either a single global clock or clock triplication) in the TMR specification may introduce useful skew that protects against glitch propagation through the designed device. The resultant layout generated from the TMR configuration may relax constraints imposed on register transfer level (RTL) engineers to make rad-hard designs, as automation introduces TMR storage registers, memory element spacing, and clock delay/triplication with minimal designer input.
FILED Tuesday, January 31, 2023
APPL NO 18/103970
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Electric Digital Data Processing
G06F 30/327 (20200101) Original (OR) Class
G06F 30/392 (20200101)
G06F 30/396 (20200101)
G06F 2119/02 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967629 Das et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Kansas State University Research Foundation (Manhattan, Kansas);  Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Kansas State University Research Foundation (Manhattan, Kansas);  Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Suprem R. Das (Manhattan, Kansas);  David B. Janes (West Lafayette, Indiana);  Jiseok Kwon (Lafayette, Indiana)
ABSTRACT A semiconductor device and methods of fabricating and using the same are provided. The semiconductor device comprises a channel region and at least a first, second, and third electrode. The channel region includes a compound having a transition metal and a chalcogen. The thickness of the channel region is about 3 to about 40 atomic layers.
FILED Saturday, June 22, 2019
APPL NO 17/253180
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/02568 (20130101)
H01L 29/24 (20130101)
H01L 29/435 (20130101) Original (OR) Class
H01L 29/7606 (20130101)
H01L 29/66969 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967854 Varigonda et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Cummins Inc. (Columbus, Indiana)
ASSIGNEE(S) CUMMINS INC. (Columbus, Indiana)
INVENTOR(S) Subbarao Varigonda (Columbus, Indiana);  Jaroslaw Leonarski (Columbus, Indiana);  Harsha R. Ademane (Indianapolis, Indiana)
ABSTRACT A mild-hybrid energy storage system architecture is provided, comprising: a battery; an ultracapacitor connected in parallel with the battery; a passive battery pre-charge circuit connected between a terminal of the battery and a DC bus; a battery main contactor connected in parallel with the battery pre-charge circuit between the terminal of the battery and the DC bus; a passive ultracapacitor pre-charge circuit connected between a terminal of the ultracapacitor and the DC bus; an ultracapacitor main contactor connected in parallel with the ultracapacitor pre-charge circuit between the terminal of the ultracapacitor and the DC bus; and a control module configured to independently control operation of the battery pre-charge circuit, the battery main contactor, the ultracapacitor pre-charge circuit and the ultracapacitor main contactor.
FILED Thursday, January 23, 2020
APPL NO 17/433116
ART UNIT 2859 — Printing/Measuring and Testing
CURRENT CPC
Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 6/28 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/44 (20130101)
H01M 10/48 (20130101)
H01M 10/0525 (20130101)
H01M 2220/20 (20130101)

Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/345 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11968263 Rajagopal et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Ram Rajagopal (Stanford, California);  Gustavo Vianna Cezar (Stanford, California);  Thomas Navidi (Stanford, California);  Elizabeth Buechler (Stanford, California);  Abbas El Gamal (Stanford, California)
ABSTRACT A method and a system for managing power resources. One or more measurements received from one or more sensors communicatively coupled to at least one processor are processed. The sensors monitor and measure at least one of: one or more operational parameters associated with operation of at least one equipment, one or more external parameters associated with an environment of the equipment, and one or more power parameters associated with a power consumption by the equipment. Based on the processed one or more measurements, one or more future operational parameters associated with an operation of the are determined. The operation of the equipment is controlled using the determined future operational parameters.
FILED Thursday, March 24, 2022
APPL NO 17/703621
ART UNIT 2454 — Computer Networks
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 3/003 (20200101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 67/125 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11964252 Shaikh et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Prostate Cancer Research Program (USAMRMCPCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) XPLOSAFE, LLC (Stillwater, Oklahoma)
ASSIGNEE(S) XPLOSAFE, LLC (Stillwater, Oklahoma)
INVENTOR(S) Shoaib F. Shaikh (Stillwater, Oklahoma);  Allen W. Apblett (Stillwater, Oklahoma);  Nicholas F. Materer (Stillwater, Oklahoma);  Evgueni Kadossov (Stillwater, Oklahoma);  Michael L. Teicheira (Stillwater, Oklahoma)
ABSTRACT The present invention provides an improved sorbent and corresponding device(s) and uses thereof for the capture and stabilization of volatile organic compounds (VOC) or semi-volatile organic compounds (SVOC) from a gaseous atmosphere. The sorbent is capable of rapid and high uptake of one or more compounds and provides quantitative release (recovery) of the compound(s) when exposed to elevated temperature and/or organic solvent. Uses of particular improved grades of mesoporous silica are disclosed.
FILED Monday, January 25, 2021
APPL NO 17/157526
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 2253/106 (20130101)
B01D 2257/708 (20130101)
B01D 2259/4583 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/103 (20130101) Original (OR) Class
B01J 20/3204 (20130101)
B01J 20/3219 (20130101)
B01J 20/3246 (20130101)
B01J 20/3293 (20130101)
B01J 20/28021 (20130101)
B01J 20/28064 (20130101)
B01J 20/28073 (20130101)
B01J 20/28076 (20130101)
B01J 20/28083 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 33/18 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/82 (20130101)
C01P 2004/04 (20130101)
C01P 2004/13 (20130101)
C01P 2006/12 (20130101)
C01P 2006/14 (20130101)
C01P 2006/16 (20130101)

Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 21/0091 (20130101)
C06B 23/00 (20130101)
C06B 45/00 (20130101)

Blasting
F42D 5/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11964997 Kazakov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) RealSeq Biosciences, Inc. (Santa Cruz, California)
ASSIGNEE(S) RealSeq Biosciences, Inc. (Santa Cruz, California)
INVENTOR(S) Sergei A. Kazakov (San Jose, California);  Sergio Barberan-Soler (Santa Cruz, California);  Anne Dallas (Santa Cruz, California);  Brian H. Johnston (Scotts Valley, California)
ABSTRACT Disclosed herein are methods and compositions for the detection of small RNAs in a sample. The methods and compositions disclosed herein may be used for preparing sequencing libraries of the small RNAs, fragments of RNAs and DNAs.
FILED Friday, March 12, 2021
APPL NO 17/199968
ART UNIT 1675 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/00 (20130101)
C07H 21/02 (20130101) Original (OR) Class
C07H 21/04 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 19/34 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)
C12Q 1/6855 (20130101)
C12Q 1/6855 (20130101)
C12Q 1/6874 (20130101)
C12Q 2525/186 (20130101)
C12Q 2525/191 (20130101)
C12Q 2525/307 (20130101)
C12Q 2531/125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965074 Strasser et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
Office of Science (DOE-SC)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Giner, Inc. (Newton, Massachusetts)
ASSIGNEE(S) GINER, INC. (Newton, Massachusetts)
INVENTOR(S) Derek J. Strasser (Marlborough, Massachusetts);  Hui Xu (Acton, Massachusetts);  Judith Lattimer (Cambridge, Massachusetts)
ABSTRACT Anion exchange membrane and methods of making and using the same. In one embodiment, the anion exchange membrane may be made by a method that includes a two-step polymerization. In the first step, an α-olefin monomer containing a pendant halide, such as 8-bromo-1-octene, may be polymerized by Ziegler-Natta polymerization to form a first polymer portion, the first polymer portion being a homopolymer. In the second step, the polymerization is charged with a non-functionalized α-olefin monomer, such as ethylene, thereby forming a second polymer portion, the second polymer being a copolymer made up predominantly of the non-functionalized olefin monomer. If desired, a small amount of an α-olefin monomer containing a crosslinking functionality may be included in the first and/or second steps. Following the two-step polymerization, the polymer is fabricated into a thin film. Thereafter, the thin film may be functionalized by replacing the pendant halides with pendant cations.
FILED Thursday, June 09, 2022
APPL NO 17/836733
ART UNIT 1764 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 226/02 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/2231 (20130101) Original (OR) Class
C08J 2339/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11966284 Lameres et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) MONTANA STATE UNIVERSITY (Bozeman, Montana);  RESILIENT COMPUTING, LLC (Bozeman, Montana)
ASSIGNEE(S) MONTANA STATE UNIVERSITY (Bozeman, Montana);  RESILIENT COMPUTING, LLC (Bozeman, Montana)
INVENTOR(S) Brock J. Lameres (Bozeman, Montana);  Christopher Michel Major (Bozeman, Montana)
ABSTRACT A fault-tolerant computer system includes a plurality of processors configured to simultaneously execute identical sets of processor-executable instructions, each of the plurality of processors containing a processor core including one or more registers and a local memory, an arbiter configured to read each of the registers of the plurality of processors, detect incorrect register values, and overwrite the registers containing the incorrect register values with corrected register values, and a memory scrubber configured to read each address of the local memories of the plurality of processors, detect incorrect memory values, and overwrite addresses containing the incorrect memory values with corrected memory values. In various embodiments, the computer system may be implemented using one or more field programmable gate arrays (FPGAs).
FILED Tuesday, October 10, 2023
APPL NO 18/484106
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/16 (20130101)
G06F 11/0721 (20130101)
G06F 11/0793 (20130101) Original (OR) Class
G06F 11/3024 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11967678 Lin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) SOLID ENERGIES INC. (Garden Grove, California)
ASSIGNEE(S) Solid Energies, Inc. (Anaheim, California)
INVENTOR(S) Zhigang Lin (Garden Grove, California);  Chunhu Tan (Garden Grove, California);  Tianyu Meng (Garden Grove, California)
ABSTRACT Electrolyte-infiltrated composite electrode includes an electrolyte component consisting of a polymer matrix with ceramic nanoparticles embedded in the matrix to form a networking structure of electrolyte. Suitable ceramic nanoparticles have the basic formula Li7La3Zr2O12 (LLZO) and its derivatives such as AlxLi7-xLa3Zr2-y-zTayNbzO12 where x ranges from 0 to 0.85, y ranges from 0 to 0.50 and z ranges from 0 to 0.75, wherein at least one of x, y and z is not equal to 0. The networking structure of the electrolyte establishes an effective lithium-ion transport pathway in the electrode and strengthens the contact between electrode layer and solid-state electrolyte resulting in higher lithium-ion electrochemical cell's cycling stability and longer battery life. Sold-state electrolytes incorporating the ceramic particles demonstrate improved performance. Large dimensional electrolyte-infiltrated composite electrode sheets can be used in all solid-state lithium electrochemical pouch cells which can be assembled into battery packs.
FILED Monday, January 16, 2023
APPL NO 18/097384
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/505 (20130101)
H01M 4/525 (20130101)
H01M 4/622 (20130101)
H01M 4/625 (20130101)
H01M 10/0525 (20130101)
H01M 10/0562 (20130101) Original (OR) Class
H01M 2004/021 (20130101)
H01M 2300/0071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11964252 Shaikh et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Prostate Cancer Research Program (USAMRMCPCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) XPLOSAFE, LLC (Stillwater, Oklahoma)
ASSIGNEE(S) XPLOSAFE, LLC (Stillwater, Oklahoma)
INVENTOR(S) Shoaib F. Shaikh (Stillwater, Oklahoma);  Allen W. Apblett (Stillwater, Oklahoma);  Nicholas F. Materer (Stillwater, Oklahoma);  Evgueni Kadossov (Stillwater, Oklahoma);  Michael L. Teicheira (Stillwater, Oklahoma)
ABSTRACT The present invention provides an improved sorbent and corresponding device(s) and uses thereof for the capture and stabilization of volatile organic compounds (VOC) or semi-volatile organic compounds (SVOC) from a gaseous atmosphere. The sorbent is capable of rapid and high uptake of one or more compounds and provides quantitative release (recovery) of the compound(s) when exposed to elevated temperature and/or organic solvent. Uses of particular improved grades of mesoporous silica are disclosed.
FILED Monday, January 25, 2021
APPL NO 17/157526
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 2253/106 (20130101)
B01D 2257/708 (20130101)
B01D 2259/4583 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/103 (20130101) Original (OR) Class
B01J 20/3204 (20130101)
B01J 20/3219 (20130101)
B01J 20/3246 (20130101)
B01J 20/3293 (20130101)
B01J 20/28021 (20130101)
B01J 20/28064 (20130101)
B01J 20/28073 (20130101)
B01J 20/28076 (20130101)
B01J 20/28083 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 33/18 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/82 (20130101)
C01P 2004/04 (20130101)
C01P 2004/13 (20130101)
C01P 2006/12 (20130101)
C01P 2006/14 (20130101)
C01P 2006/16 (20130101)

Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 21/0091 (20130101)
C06B 23/00 (20130101)
C06B 45/00 (20130101)

Blasting
F42D 5/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11968540 Nguyen et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland)
INVENTOR(S) Thao Tran-Nhu Nguyen (McLean, Virginia);  Michael Rafat Souryal (Arlington, Virginia)
ABSTRACT Systems and methods for independently managing wireless transmission by individual spectrum access systems in a radio frequency spectrum shared by a plurality of spectrum access systems. An example method includes: receiving, by the spectrum access system, an interference budget from a sensor; determining, by the spectrum access system, secondary users managed by the spectrum access system in a radio frequency spectrum shared by a plurality of spectrum access systems; managing a move list for the spectrum access system independently of the other spectrum access systems in an absence of exchange of spectrum grant information with the other spectrum access systems; and determining the move list for the spectrum access system from a first moment and a second moment of an aggregate interference distribution such that the spectrum access system provides grants to its secondary users in a dynamic protection area of the spectrum access system.
FILED Monday, June 07, 2021
APPL NO 17/340819
ART UNIT 2476 — Multiplex and VoIP
CURRENT CPC
Wireless Communication Networks
H04W 16/14 (20130101) Original (OR) Class
H04W 72/0453 (20130101)
H04W 72/541 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 11964252 Shaikh et al.
FUNDED BY
Department of Homeland Security (DHS)
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Prostate Cancer Research Program (USAMRMCPCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) XPLOSAFE, LLC (Stillwater, Oklahoma)
ASSIGNEE(S) XPLOSAFE, LLC (Stillwater, Oklahoma)
INVENTOR(S) Shoaib F. Shaikh (Stillwater, Oklahoma);  Allen W. Apblett (Stillwater, Oklahoma);  Nicholas F. Materer (Stillwater, Oklahoma);  Evgueni Kadossov (Stillwater, Oklahoma);  Michael L. Teicheira (Stillwater, Oklahoma)
ABSTRACT The present invention provides an improved sorbent and corresponding device(s) and uses thereof for the capture and stabilization of volatile organic compounds (VOC) or semi-volatile organic compounds (SVOC) from a gaseous atmosphere. The sorbent is capable of rapid and high uptake of one or more compounds and provides quantitative release (recovery) of the compound(s) when exposed to elevated temperature and/or organic solvent. Uses of particular improved grades of mesoporous silica are disclosed.
FILED Monday, January 25, 2021
APPL NO 17/157526
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Separation
B01D 53/02 (20130101)
B01D 2253/106 (20130101)
B01D 2257/708 (20130101)
B01D 2259/4583 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/103 (20130101) Original (OR) Class
B01J 20/3204 (20130101)
B01J 20/3219 (20130101)
B01J 20/3246 (20130101)
B01J 20/3293 (20130101)
B01J 20/28021 (20130101)
B01J 20/28064 (20130101)
B01J 20/28073 (20130101)
B01J 20/28076 (20130101)
B01J 20/28083 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 33/18 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/82 (20130101)
C01P 2004/04 (20130101)
C01P 2004/13 (20130101)
C01P 2006/12 (20130101)
C01P 2006/14 (20130101)
C01P 2006/16 (20130101)

Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives
C06B 21/0091 (20130101)
C06B 23/00 (20130101)
C06B 45/00 (20130101)

Blasting
F42D 5/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11968440 Vemury
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Arun Vemury (North Bethesda, Maryland)
ABSTRACT A system for generating a privacy protected image. The system may have a detection logic and obscuring logic configured to detect one or more identity-correlated object categories. The system may provide automatic selection of a type of obscuring to be used based on the detected category; wherein said automatic selection includes automatically selecting among a plurality of different, category specific types of reversible obscuring. The detection logic and obscuring logic may include an automatic category-specific selecting between irreversible obscuring and reversible obscuring. The system may comprise a privacy protected image output logic configured to generate the privacy protected image.
FILED Thursday, March 16, 2023
APPL NO 18/122415
ART UNIT 2637 — Optical Communications
CURRENT CPC
Electric Digital Data Processing
G06F 21/6245 (20130101)

Image Data Processing or Generation, in General
G06T 5/002 (20130101)
G06T 7/20 (20130101)
G06T 7/70 (20170101)
G06T 2207/20008 (20130101)
G06T 2207/20224 (20130101)
G06T 2207/30201 (20130101)

Image or Video Recognition or Understanding
G06V 10/25 (20220101)
G06V 10/764 (20220101)

Pictorial Communication, e.g Television
H04N 5/272 (20130101)
H04N 23/51 (20230101)
H04N 23/64 (20230101)
H04N 23/611 (20230101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 11964558 Hök et al.
FUNDED BY
Department of Transportation (USDOT)
National Highway Traffic Safety Administration (NHTSA)
APPLICANT(S) Automotive Coalition for Traffic Safety, Inc. (Sterling, Virginia)
ASSIGNEE(S) Automotive Coalition for Traffic Safety, Inc. (Leesburg, Virginia)
INVENTOR(S) Bertil Hök (Västerås, Sweden);  Raimo Gester (Västerås, Sweden);  Jonas Ljungblad (Stockholm, Sweden);  Håkan Pettersson (Floda, Sweden)
ABSTRACT Methods and apparatus allow for passive determination of a driver's Breath Alcohol Concentration (BrAC). Alcohol concentrations can be determined from exhaled breath, however inconvenience to a driver is often a barrier for incorporation of BrAC sensors into vehicles. The methods and apparatus allow for passive determination of a driver's BrAC, while detecting and accounting for a wide range of environmental conditions that may reduce the accuracy of a passive BrAC reading.
FILED Tuesday, August 31, 2021
APPL NO 17/462318
ART UNIT 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 28/063 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/0067 (20130101)
G01N 33/4972 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11965967 Che et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
Department of Transportation (USDOT)
APPLICANT(S) Oregon State University (Corvallis, Oregon)
ASSIGNEE(S) Oregon State University (Corvallis, Oregon)
INVENTOR(S) Erzhuo Che (Corvallis, Oregon);  Michael Olsen (Corvallis, Oregon)
ABSTRACT A computer implemented scheme for a light detection and ranging (LIDAR) system where point cloud feature extraction and segmentation by efficiently is achieved by: (1) data structuring; (2) edge detection; and (3) region growing.
FILED Wednesday, November 16, 2022
APPL NO 18/056247
ART UNIT 2488 — Recording and Compression
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/4804 (20130101)
G01S 17/89 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 7/11 (20170101)
G06T 7/13 (20170101)
G06T 7/136 (20170101)
G06T 7/174 (20170101)
G06T 7/187 (20170101)
G06T 2207/10028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11965799 Onuma et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Eleanya Onuma (Springdale, Maryland);  Manohar Deshpande (Odenton, Maryland);  Mark Stephen (Catonsville, Maryland);  Fabrizio Gambini (Santa Barbara, California);  Charles Turner (Greenbelt, Maryland)
ABSTRACT An electromagnetic signal detector includes a photonic crystal substrate, an antenna disposed on the substrate and having an active feed region and a ground region spaced apart from one another by a gap, a photonic crystal disposed on the substrate at the gap, and an electro optic polymer disposed on the photonic crystal.
FILED Tuesday, September 13, 2022
APPL NO 17/943870
ART UNIT 2878 — Optics
CURRENT CPC
Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 11/0228 (20130101) Original (OR) Class

Antennas, i.e Radio Aerials
H01Q 9/0407 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11966284 Lameres et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) MONTANA STATE UNIVERSITY (Bozeman, Montana);  RESILIENT COMPUTING, LLC (Bozeman, Montana)
ASSIGNEE(S) MONTANA STATE UNIVERSITY (Bozeman, Montana);  RESILIENT COMPUTING, LLC (Bozeman, Montana)
INVENTOR(S) Brock J. Lameres (Bozeman, Montana);  Christopher Michel Major (Bozeman, Montana)
ABSTRACT A fault-tolerant computer system includes a plurality of processors configured to simultaneously execute identical sets of processor-executable instructions, each of the plurality of processors containing a processor core including one or more registers and a local memory, an arbiter configured to read each of the registers of the plurality of processors, detect incorrect register values, and overwrite the registers containing the incorrect register values with corrected register values, and a memory scrubber configured to read each address of the local memories of the plurality of processors, detect incorrect memory values, and overwrite addresses containing the incorrect memory values with corrected memory values. In various embodiments, the computer system may be implemented using one or more field programmable gate arrays (FPGAs).
FILED Tuesday, October 10, 2023
APPL NO 18/484106
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/16 (20130101)
G06F 11/0721 (20130101)
G06F 11/0793 (20130101) Original (OR) Class
G06F 11/3024 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Interior (DOI) 

US 11965001 Piraner et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Interior (DOI)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Dan I. Piraner (San Francisco, California);  Mikhail Shapiro (Pasadena, California)
ABSTRACT Provided herein are thermomer monomer, thermomer dimers, thermomer monomeric constructs, thermomer dimeric complexes, and related gene expression cassette vectors, cells, surfaces devices, compositions methods and systems, that provide a thermobioswitch suitable to control location and/or binding of cargo moiety of interest in a temperature regulated manner.
FILED Monday, July 13, 2020
APPL NO 16/927590
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/255 (20130101) Original (OR) Class
C07K 2319/73 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US 11963866 Brockman et al.
FUNDED BY
U.S. State Government
Commonwealth of Kentucky
Kentucky Cabinet for Economic Development (KY-CED)
APPLICANT(S) Brockman-Hastings LLC (Lexington, Kentucky)
ASSIGNEE(S) Brockman-Hastings LLC (Lexington, Kentucky)
INVENTOR(S) Edward Britt Brockman (Louisville, Kentucky);  Jeffrey Todd Hastings (Lexington, Kentucky);  Carlos Andres Jarro (Lexington, Kentucky);  James L. Russell (Lexington, Kentucky)
ABSTRACT An eye implant has a body including (a) a receiver, (b) a first mounting clip and (c) a second mounting clip. The receiver is adapted to hold an intraocular device to be implanted in an eye. The receiver, the first mounting clip and the second mounting clip generally extend along a common arc.
FILED Tuesday, December 29, 2020
APPL NO 17/136833
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/03 (20130101)
A61B 5/4839 (20130101)
A61B 5/6821 (20130101)
A61B 5/6883 (20130101)
A61B 5/14555 (20130101)
A61B 2562/0247 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/14 (20130101)
A61F 2/16 (20130101) Original (OR) Class
A61F 9/0017 (20130101)
A61F 2002/1681 (20130101)
A61F 2002/16902 (20150401)
A61F 2002/16903 (20150401)
A61F 2220/0008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, April 23, 2024.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240423.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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