FedInvent™ Patents
Patent Details for Tuesday, May 14, 2024
This page was updated on Saturday, June 08, 2024 at 03:50 PM GMT
Department of Health and Human Services (HHS)
| US 11980369 | Goldie et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vivonics, Inc. (Bedford, Massachusetts) |
| ASSIGNEE(S) | Vivonics, Inc. (Bedford, Massachusetts) |
| INVENTOR(S) | James H. Goldie (Lexington, Massachusetts); Brendan LaBrecque (Middleton, Massachusetts); Anna M Galea (Stow, Massachusetts); Eric Klem (Lexington, Massachusetts); Thomas Doyle (Brentwood, Tennessee); Ian Cohen (Broomfield, Colorado); Tim Robinson (Sandown, New Hampshire) |
| ABSTRACT | A pulmonary artery flow restrictor system includes a funnel shaped membrane with a proximal base and a restrictive distal opening which is stretchable to larger sizes. A self-expanding frame is attached to the proximal base of the membrane for securing the membrane within the pulmonary artery. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/672893 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/12036 (20130101) Original (OR) Class A61B 17/12109 (20130101) A61B 17/12172 (20130101) A61B 17/12177 (20130101) A61B 2017/12054 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/82 (20130101) A61F 2002/068 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 29/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980453 | Zhou et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Wenjun Zhou (Davis, California); Oybek Kholiqov (Davis, California); Vivek Jay Srinivasan (Davis, California) |
| ABSTRACT | The disclosed embodiments provide a system that non-invasively analyzes blood flow in a sample of living tissue. During operation, the system obtains light from a temporally coherent source, and splits the obtained light between a reference path and a sample path. Next, the system multiply scatters light from the sample path by passing the light through the sample. The system then recombines light from the reference path and the multiply scattered light from the sample path. Next, the system uses a sensor array to detect an interference pattern resulting from the recombination. Finally, the system analyzes signals from the sensor array to determine a blood flow in the sample. |
| FILED | Monday, April 15, 2019 |
| APPL NO | 17/046246 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0261 (20130101) Original (OR) Class A61B 5/4064 (20130101) A61B 2562/04 (20130101) A61B 2562/0238 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980468 | Mendenhall et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); UPMC (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); UPMC (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | George Stuart Mendenhall (Pittsburgh, Pennsylvania); Matthew Jones (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed are wearable devices, such as rings and bracelets, for monitoring and diagnosing cardiovascular conditions of a wearer, along with related systems, algorithms and methods. The disclosed wearable devices can continuously monitor the wearer's cardiovascular status by measuring heart rate, motion, blood oxygenation, and/or other properties of the wearer. Disclosed wearable devices can further comprise three EKG electrodes, including a first electrode on the inner surface adapted to detect a signal from the finger/wrist, a second electrode on the outer surface adapted to detect a cardiovascular signal from a finger of the opposing hand, and a third electrode on the outer surface of the frame adapted to detect a cardiovascular signal from a EKG lead location on the wearer's chest or leg. The wearable devices can be linked wirelessly to a mobile device that the person can interact with, and can further be linked to other distributed system components and healthcare providers. |
| FILED | Friday, October 23, 2020 |
| APPL NO | 17/078527 |
| ART UNIT | 3796 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/11 (20130101) A61B 5/0022 (20130101) A61B 5/25 (20210101) Original (OR) Class A61B 5/0205 (20130101) A61B 5/349 (20210101) A61B 5/389 (20210101) A61B 5/683 (20130101) A61B 5/02438 (20130101) A61B 5/6826 (20130101) A61B 5/7275 (20130101) A61B 5/14552 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/048 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980473 | Berry et al. |
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| FUNDED BY |
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| APPLICANT(S) | Brent M. Berry (Rochester, Minnesota); Gary C. Sieck (Rochester, Minnesota); Gregory A. Worrell (Rochester, Minnesota); Benjamin H. Brinkmann (Byron, Minnesota); Yogatheesan Varatharajah (Urbana, Illinois); Vaclav Kremen (Rochester, Minnesota); Ravishankar Krishnan Iyer (Champaign, Illinois); Zbigniew Kalbarczyk (Urbana, Illinois); Jan Cimbalnik (Brno, Czech Republic) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); The Board of Trustees of the University of Illinois and St. Anne's University Hospital Brno (Urbana, Illinois) |
| INVENTOR(S) | Brent M. Berry (Rochester, Minnesota); Gary C. Sieck (Rochester, Minnesota); Gregory A. Worrell (Rochester, Minnesota); Benjamin H. Brinkmann (Byron, Minnesota); Yogatheesan Varatharajah (Urbana, Illinois); Vaclav Kremen (Rochester, Minnesota); Ravishankar Krishnan Iyer (Champaign, Illinois); Zbigniew Kalbarczyk (Urbana, Illinois); Jan Cimbalnik (Brno, Czech Republic) |
| ABSTRACT | This specification discloses systems, methods, devices, and other techniques for determining the location of a seizure-generating region of the brain of a mammal. |
| FILED | Friday, May 25, 2018 |
| APPL NO | 16/616771 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/076 (20130101) A61B 5/369 (20210101) Original (OR) Class A61B 5/725 (20130101) A61B 5/4094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980498 | Reiche et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Christopher F. Reiche (Salt Lake City, Utah); Florian Solzbacher (Salt Lake City, Utah); Navid Farhoudi (Salt Lake City, Utah); Steven M. Blair (Salt Lake City, Utah); Jules J. Magda (Salt Lake City, Utah); Lars B. Laurentius (Cottonwood Heights, Utah); Prattay Deepta Kairy (Salt Lake City, Utah) |
| ABSTRACT | Systems and methods for measuring changes in smart hydrogel microresonator structures positioned in an in vivo or other environment, having an acoustic resonance frequency in an ultrasound range. The system includes a smart hydrogel microresonator structure positioned within the environment configured to exhibit a change in resonance frequency in response to interaction with one or more predefined analytes in the environment. The system includes an ultrasound transducer for querying the smart hydrogel microresonator structure at or near its resonance frequency. The system also includes a computer system configured to receive ultrasound data as provided by query of the smart hydrogel microresonator structure and to determine changes in resonance frequency, amplitude or intensity of the ultrasound query wave, or mean grayscale value (MGV) associated with the ultrasound data of the smart hydrogel microresonator structure due to the change in resonance frequency. Such change can be correlated to concentration of the analyte. |
| FILED | Friday, May 07, 2021 |
| APPL NO | 17/315039 |
| ART UNIT | 3798 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/4272 (20130101) Original (OR) Class A61B 8/4483 (20130101) A61B 8/5207 (20130101) A61B 2562/028 (20130101) A61B 2562/0204 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980534 | Hurtado et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York); Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Andres Hurtado (Baltimore, Maryland); Ryan James Gilbert (Houghton, Michigan); Han Bing Wang (Houghton, Michigan); Jared M. Cregg (Houghton, Michigan); Michael E. Mullins (Houghton, Michigan); Martin Oudega (Munhall, Pennsylvania) |
| ABSTRACT | One aspect of the invention provides a three-dimensional scaffold including at least one layer of highly-aligned fibers. The at least one layer of highly-aligned fibers is curved in a direction substantially perpendicular to a general direction of the fibers. Another aspect of the invention provides a method for fabricating a three-dimensional scaffold. The method includes: electro spinning a plurality of fibers to produce at least one layer of highly-aligned fibers and forming the at least one layer of highly-aligned fibers into a three-dimensional scaffold without disturbing the alignment of the highly-aligned polymer fibers. A further aspect of the invention provides methods for using a three-dimensional scaffold to treat nerve or spinal cord injury. |
| FILED | Monday, July 29, 2019 |
| APPL NO | 16/524473 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/00 (20130101) Original (OR) Class A61F 2/04 (20130101) A61F 2/0063 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/54 (20130101) A61L 27/383 (20130101) A61L 27/3834 (20130101) A61L 2300/254 (20130101) A61L 2300/414 (20130101) A61L 2300/416 (20130101) A61L 2430/32 (20130101) A61L 2430/38 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0076 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 16/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980587 | Wood et al. |
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| FUNDED BY |
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| APPLICANT(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| ASSIGNEE(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| INVENTOR(S) | Ryan P. Wood (Bedford, New Hampshire); Michael J. Haynes (Manchester, New Hampshire); Hans Erik Johnson (Salem, New Hampshire); Thaddeus Joseph Hughes (Manchester, New Hampshire); Robert Houston Lawler, Jr. (Manchester, New Hampshire) |
| ABSTRACT | A liquid concentrate generation system may comprise a manifold having an inlet receptacle including a first piercing member, an outlet receptacle including a second piercing member, and a flow channel connecting the inlet receptacle and outlet receptacle. The system may further comprise a cartridge having an inlet port and an outlet port sealed by a respective first and second cover. The inlet and outlet port may be respectively configured to displace within the inlet receptacle and outlet receptacle from an unspiked position to a spiked position. First and second piercing members may be in communication with the flow channel and spaced apart respectively from the first and second cover in the unspiked position. The first and second piercing members may be isolated from the flow channel and may respectively puncture the first and second cover in the spiked position. |
| FILED | Friday, September 24, 2021 |
| APPL NO | 17/484425 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/10 (20130101) A61J 1/2013 (20150501) Original (OR) Class A61J 1/2037 (20150501) A61J 1/2079 (20150501) A61J 2205/60 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 35/7137 (20220101) Machines, Apparatus or Devices For, or Methods Of, Packaging Articles or Materials; Unpacking B65B 3/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980614 | Lin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Belite Bio, Inc (Cayman Island, Cayman Islands); THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | Belite Bio, Inc (Grand Cayman, Cayman Islands); The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Yu-Hsin Tom Lin (San Diego, California); Cheng-Chi Irene Wang (San Diego, California); Konstantin Petrukhin (New Windsor, New York) |
| ABSTRACT | Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for the treatment of retinal binding protein (RBP4) related diseases, such as obesity and the like. |
| FILED | Monday, April 12, 2021 |
| APPL NO | 17/228590 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/519 (20130101) A61K 31/4545 (20130101) Original (OR) Class A61K 31/4985 (20130101) A61K 31/5365 (20130101) A61K 31/5383 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980616 | Laberge et al. |
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| FUNDED BY |
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| APPLICANT(S) | Buck Institute for Research on Aging (Novato, California); Unity Biotechnology, Inc. (South San Francisco, California); Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); Buck Institute for Research on Aging (Novato, California); Unity Biotechnology, Inc. (Brisbane, California) |
| INVENTOR(S) | Remi-Martin Laberge (San Francisco, California); Judith Campisi (Berkeley, California); Marco Demaria (Groningen, Netherlands); Nathaniel David (Brisbane, California); James L. Kirkland (Rochester, Minnesota); Tamar Tchkonia (Rochester, Minnesota); Yi Zhu (Rochester, Minnesota) |
| ABSTRACT | Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/114379 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0073 (20130101) A61K 31/404 (20130101) A61K 31/428 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/728 (20130101) A61K 31/4178 (20130101) A61K 31/4375 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 47/36 (20130101) A61K 47/6807 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) A61P 11/00 (20180101) A61P 25/28 (20180101) A61P 27/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0081 (20130101) C12N 15/113 (20130101) C12N 2320/30 (20130101) C12N 2501/999 (20130101) C12N 2503/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980620 | Doulatov et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Sergei Doulatov (Seattle, Washington); George Q. Daley (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates generally to methods for treatment of ribosomal disorders and ribosomopathy, e.g. Diamond Blackfan anemia (DBA). In some embodiments, the invention relates to methods for the use of a small-molecule autophagy modulator for treatment of ribosomal disorders and ribosomopathy. The invention also relates to small molecule drug discovery and methods of screening compositions to determine their effectiveness for treatment of ribosomal disorders and ribosomopathies. |
| FILED | Thursday, June 08, 2017 |
| APPL NO | 16/620064 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/00 (20180101) A61P 7/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) C12N 15/86 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980628 | Powell |
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| FUNDED BY |
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| APPLICANT(S) | CLARK ATLANTA UNIVERSITY, INC. (Atlanta, Georgia) |
| ASSIGNEE(S) | CLARK ATLANTA UNIVERSITY, INC. (Atlanta, Georgia) |
| INVENTOR(S) | Joann Brooks Powell (Atlanta, Georgia) |
| ABSTRACT | Simultaneous inhibition of the aryl hydrocarbon receptor (AhR) and SRC abolishing androgen receptor (AR) signaling in prostate cancer cells is disclosed herein as an effective treatment for prostate cancer. Provided herein is a therapeutic composition that comprises an aryl hydrocarbon receptor (AhR) antagonist and an SRC inhibitor. In one embodiment, the therapeutic composition further comprises a pharmaceutical excipient. In one embodiment, the AhR antagonist is CH223191 and the SRC inhibitor is PP2 and the therapeutic composition further comprises a pharmaceutical excipient. Methods of using the therapeutic composition to treat prostate cancer or to inhibit prostate cancer cells are also disclosed. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 17/459762 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 31/655 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980630 | Radtke |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE COUNTY (Baltimore, Maryland) |
| INVENTOR(S) | Katherine L. Radtke (Baltimore, Maryland) |
| ABSTRACT | The present invention is directed to compounds, methods and compositions for treating or preventing viral infections using nucleosides analogs. Specifically, the present invention provides for the design and synthesis of acyclic fleximer nucleoside analogues having increased flexibility and ability to alter their conformation structures to provide increased antiviral activity potential with the result of inhibiting flaviviruses, filoviruses and/or coronaviruses. |
| FILED | Thursday, January 06, 2022 |
| APPL NO | 17/569804 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/675 (20130101) A61K 31/683 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980640 | Qin et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Haiying Qin (Potomac, Maryland); Crystal L Mackall (Stanford, California); Terry J. Fry (Bethesda, Maryland) |
| ABSTRACT | An embodiment of the invention provides bicistronic chimeric antigen receptor (CAR) amino acid constructs. Nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions relating to the CAR constructs are disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed. Methods of making the CAR constructs are disclosed. |
| FILED | Tuesday, May 15, 2018 |
| APPL NO | 16/613187 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/395 (20130101) C07K 14/7051 (20130101) C07K 16/2803 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980654 | Huttenlocher et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Anna Huttenlocher (Madison, Wisconsin); Deane Mosher (Madison, Wisconsin); Valeriu Bortnov (Madison, Wisconsin); David Bennin (Madison, Wisconsin); Ruth Anne Houseright (Madison, Wisconsin); Frances M Smith (Madison, Wisconsin) |
| ABSTRACT | A method to inhibit neutrophil recruitment to damaged tissue, thereby inhibiting inflammation in a subject. The method includes administering to an anti-inflammatory amount of a myeloid-derived growth factor (“MYDGF”). Also disclosed are corresponding pharmaceutical compositions of matter containing the MYDGF. |
| FILED | Wednesday, September 22, 2021 |
| APPL NO | 17/481490 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/18 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980667 | Joshi |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Shailendra Joshi (Ho Ho Kus, New Jersey) |
| ABSTRACT | Trans-activating transcription (TAT) factor peptide oligomers coupled with functional agents can selectively complex to the anionic surface of cancerous cells. The TAT conjugates can be delivered to the locus of the tumors using intra-arterial injection during transient blood flow arrest. |
| FILED | Monday, December 09, 2019 |
| APPL NO | 16/708063 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/08 (20130101) A61K 31/198 (20130101) A61K 31/216 (20130101) A61K 31/7076 (20130101) A61K 47/645 (20170801) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/0606 (20130101) A61M 2025/0042 (20130101) A61M 2025/1052 (20130101) A61M 2202/048 (20130101) A61M 2210/0693 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980671 | Bursac et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Nenad Bursac (Durham, North Carolina); Hung Nguyen (Durham, North Carolina); Robert Kirkton (Durham, North Carolina) |
| ABSTRACT | Disclosed herein are compositions including prokaryotic ion channel polypeptides and methods of treating voltage gated ion channel-related condition such as heart arrhythmia, chronic atrial fibrillation, damage from myocardial infarction, damage from stroke, and chronic ischemia. |
| FILED | Thursday, July 26, 2018 |
| APPL NO | 16/046939 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0008 (20130101) A61K 48/0058 (20130101) Original (OR) Class A61K 48/0075 (20130101) A61K 48/0083 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/06 (20180101) A61P 9/10 (20180101) Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980687 | Venditto et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Vincent J. Venditto (Lexington, Kentucky); Ahmed Abdel-Latif (Lexington, Kentucky); Ahmed Al-Darraji (Lexington, Kentucky); Dave Feola (Lexington, Kentucky); John C. Gensel (Versailles, Kentucky) |
| ABSTRACT | A composition and method for treating a subject following myocardial infarction are provided. The composition includes a non-PEGylated liposome. The method includes administering a non-PEGylated liposome to a subject in need thereof following myocardial infarction. |
| FILED | Tuesday, April 18, 2023 |
| APPL NO | 18/136298 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 31/7048 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980735 | Oberstar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Erick Louis Oberstar (Verona, Wisconsin); Michael Antonio Speidel (Madison, Wisconsin) |
| ABSTRACT | Aspects of the disclosure are directed to methods and/or apparatuses involving modifying flow and/or concentration of an agent being injected for characterizing a vascular system. As may be implemented in accordance with one or more embodiments, a liquid including an agent is injected into a vascular system, by dynamically modulating a flow rate of the agent being injected over a range of flow rates. The vascular system is characterized based on a response of the vascular system to the dynamic modulation. In some implementations, such an approach involves using an injector that operates to separately control the rate at which an agent and other liquid such as saline are injected. These approaches can be implemented with modulation schemes using one or more of a variety of functions. |
| FILED | Wednesday, August 07, 2019 |
| APPL NO | 16/534725 |
| ART UNIT | 3798 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0263 (20130101) A61B 5/0275 (20130101) A61B 6/032 (20130101) A61B 6/481 (20130101) A61B 6/507 (20130101) A61B 8/06 (20130101) A61B 8/481 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/007 (20130101) Original (OR) Class A61M 5/1408 (20130101) A61M 5/1452 (20130101) A61M 2205/3334 (20130101) A61M 2230/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980759 | Irazoqui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Pedro Irazoqui (Lafayette, Indiana); Gabriel Omar Albors (West Lafayette, Indiana); Daniel Pederson (Lafayette, Indiana); Christopher John Quinkert (Dyer West Lafayette, Indiana); Muhammad Abdullah Arafat (West Lafayette, Indiana); Jack Williams (Lafayette, Indiana); Zhi Wang (West Lafayette, Indiana); John G. R. Jefferys (Oxford, United Kingdom); Thelma Anderson Lovick (Birmingham, United Kingdom); Terry L. Powley (West Lafayette, Indiana); Rebecca Anne Bercich (Terre Haute, Indiana); Henry Mei (Vadnais Heights, Minnesota); Jesse Paul Somann (West Lafayette, Indiana); Quan Yuan (West Lafayette, Indiana); Hansraj Singh Bhamra (San Jose, California) |
| ABSTRACT | Systems and techniques for wireless implantable devices, for example implantable biomedical devices employed for biomodulation. Some embodiments include a biomodulation system including a non-implantable assembly including a source for wireless power transfer and a data communications system, an implantable assembly including a power management module configured to continuously generate one or more operating voltage for the implantable assembly using wireless power transfer from the non-implantable assembly, a control module operably connected to at least one communication channel and at least one stimulation output, the control module including a processor unit to process information sensed via the at least one communication channel and, upon determining a condition exists, to generate an output to trigger the generation of a stimulus. |
| FILED | Monday, December 12, 2022 |
| APPL NO | 18/079716 |
| ART UNIT | 3796 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/08 (20130101) A61B 5/14539 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) A61N 1/0534 (20130101) A61N 1/0548 (20130101) A61N 1/0551 (20130101) A61N 1/3605 (20130101) A61N 1/3611 (20130101) A61N 1/3787 (20130101) A61N 1/36007 (20130101) A61N 1/36053 (20130101) A61N 1/36064 (20130101) A61N 1/36135 (20130101) Original (OR) Class A61N 1/37211 (20130101) A61N 1/37223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980768 | Carter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Calvin S. Carter (Iowa City, Iowa); Sunny C. Huang (Iowa City, Iowa); Michael J. Miller (Iowa City, Iowa); Charles C. Searby (Iowa City, Iowa); Val C. Sheffield (Iowa City, Iowa) |
| ABSTRACT | An example of subject may deliver a therapy by delivering energy to tissue. The system may comprise a magnetic field system and an electric field system. The magnetic field system may be configured to provide a magnetic field in a first direction to the tissue. The magnetic field system may include at least one magnetic field source to produce the magnetic field. The magnetic field produced by the at least one magnetic field source may include a magnetic field produced by at least one of a permanent magnet, a temporary magnet or electric current flow through a conductor. The electric field system may be configured to provide an electric field in a second direction to the tissue. The electric field system may include at least one electric field source to provide the electric field and the second direction is non-parallel to the first direction. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 17/369784 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/14532 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/10 (20130101) A61N 1/40 (20130101) A61N 1/0484 (20130101) A61N 1/36002 (20170801) A61N 1/36034 (20170801) A61N 2/00 (20130101) A61N 2/002 (20130101) Original (OR) Class A61N 2/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980849 | Guo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio); Oxford Nanopore Technologies Limited (Oxford Oxfordshire, United Kingdom) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Peixuan Guo (Dublin, Ohio); Zhouxiang Ji (Columbus, Ohio); Lakmal Jayasinghe (Headington, United Kingdom); Michael Jordan (Oxford Oxfordshire, United Kingdom) |
| ABSTRACT | Disclosed herein are compositions and methods that involve inserting connector protein channels of bacteriophage DNA packaging motors into copolymeric membranes via liposome-polymer fusion, which can be used as nanopore sensors for biomedical applications such as high throughput protein sequencing or cancer diagnosis. For example, disclosed are compositions comprising a copolymeric membrane into which a connector protein channel of a bacteriophage packaging motor has been inserted. |
| FILED | Friday, February 08, 2019 |
| APPL NO | 16/967560 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 67/0081 (20130101) B01D 69/144 (20130101) Original (OR) Class B01D 71/74 (20130101) B01D 71/80 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 2535/122 (20130101) C12Q 2563/116 (20130101) C12Q 2565/607 (20130101) C12Q 2565/631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981557 | Bandara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas); University of Rhode Island Board of Trustees (Kingston, Rhode Island) |
| ASSIGNEE(S) | SOUTHERN METHODIST UNIVERSITY (Dallas, Texas) |
| INVENTOR(S) | Y. M. Nuwan D. Y. Bandara (Canberra, Australia); Buddini I. Karawdeniya (Canberra, Australia); Jugal Saharia (Dallas, Texas); Min Jun Kim (Plano, Texas); Jason Rodger Dwyer (Providence, Rhode Island) |
| ABSTRACT | The present invention includes one or more nanopores in a SixNy membrane comprising a monoprotic surface termination, methods of making, and methods of using the one or more nanopores, where the one or more nanopores are a chemically-tuned controlled dielectric breakdown (CT-CDB) nanopore membrane, wherein the CT-CDB allows for long-term stability of measurements in the presence of only electrolyte (open pore current stability) and ability to support many molecular detection events. In addition, the CT-CBD has pore that unclog spontaneously, in response to voltage cessation or application, or both. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/232624 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00864 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 1/002 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 40/00 (20130101) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981571 | Nel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Andre E. Nel (Sherman Oaks, California); Tian Xia (Los Angeles, California); Ruibin Li (Los Angeles, California); Mark C. Hersam (Wilmette, Illinois); Nikhita D. Mansukhani (Allston, Massachusetts); Linda Guiney (Chicago, Illinois) |
| ABSTRACT | In various embodiments functionalized graphene oxide(s) are provided that demonstrate improved antimicrobial activity, where the graphene oxide(s) are functionalized to increase carbon radical (·C) density. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/531651 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/90 (20130101) A01N 59/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/08 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/198 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981626 | Pluth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Michael D. Pluth (Eugene, Oregon); Yu Zhao (Eugene, Oregon) |
| ABSTRACT | Disclosed herein are embodiments of a donor compound that releases COS and/or CS2, which can be converted to H2S. The donor compound embodiments described herein can be used to deliver H2S to a subject or a sample and further can be used to administer therapeutic agents. Methods of making and using the donor compound embodiments also are disclosed. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/322229 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 333/08 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/527 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/84 (20130101) G01N 2333/988 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981636 | Rishton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | COGNITION THERAPEUTICS, INC. (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | COGNITION THERAPEUTICS, INC. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Gilbert M. Rishton (Los Angeles, California); Gary C. Look (Santa Clara, California); Susan M. Catalano (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present disclosure relates to novel compounds of Formula I wherein each of Ra, Rb, Rd and Re is independently H; Rc is selected from the group consisting of H, hydroxyl, halo, alkyl, alkoxy, CF3, SO2CH3, and morpholino, R1 is selected from the group consisting of hydrogen, alkyl, phenyl, or —CH═C(CH3)2; and R2 is specific substituted cyclic amino groups. The invention also discloses pharmaceutical compositions containing the compounds and methods of using the compounds and pharmaceutical compositions for treating neurogenerative diseases, including Alzheimer's disease and cognitive decline. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/537110 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 205/04 (20130101) Original (OR) Class C07D 207/08 (20130101) C07D 207/16 (20130101) C07D 211/22 (20130101) C07D 211/46 (20130101) C07D 211/48 (20130101) C07D 241/04 (20130101) C07D 241/08 (20130101) C07D 265/30 (20130101) C07D 401/04 (20130101) C07D 403/06 (20130101) C07D 403/14 (20130101) C07D 405/04 (20130101) C07D 405/12 (20130101) C07D 413/14 (20130101) C07D 491/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981652 | Liotta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Dennis Liotta (Atlanta, Georgia); Stephen Traynelis (Decatur, Georgia); Yao Jing (Dunwoody, Georgia) |
| ABSTRACT | A compound according to Formula (I) or salts or prodrugs thereof and pharmaceutical formulations comprising the compound are provided herein for the treatment of neurological disorders. The disorders may include providing neuroprotection, preventing neurodegeneration, treating neuropathic pain or treating schizophrenia, psychoses or depression. Furthermore, the compounds may be used in combination with another active ingredient. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 17/042726 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/415 (20130101) A61K 31/415 (20130101) A61K 31/497 (20130101) A61K 31/497 (20130101) A61K 31/4155 (20130101) A61K 31/4155 (20130101) A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/18 (20180101) A61P 25/24 (20180101) A61P 25/28 (20180101) Heterocyclic Compounds C07D 231/06 (20130101) C07D 401/04 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 405/04 (20130101) C07D 409/04 (20130101) C07D 409/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981662 | Aguilera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Renato J. Aguilera (El Paso, Texas); Subhas S. Karki (El Paso, Texas); Sujeet Kumar (El Paso, Texas); Manuel L. Penichet (Los Angeles, California) |
| ABSTRACT | The inventors have used a differential nuclear staining (DNS) assay to discover compounds with cytotoxic activity against the CEM cell line that has been determined to be highly sensitive to a variety of anti-cancer compounds. Compounds were synthesized based on a pyrazole backbone structure. Several newly synthesized compounds have been tested to identify the compounds with highest activity. One compound identified is the SSK-3 compound which has been tested on cancer cell lines and determined that it induced apoptosis via phosphatidylserine membrane exposure and activation of caspase 3 in the CEM lymphoma cell line. |
| FILED | Wednesday, October 12, 2022 |
| APPL NO | 17/964110 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/416 (20130101) A61K 31/454 (20130101) A61K 31/4192 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Heterocyclic Compounds C07D 231/54 (20130101) C07D 403/12 (20130101) Original (OR) Class C07D 405/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981700 | Bougher, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chimerix, Inc. (Durham, North Carolina); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Chimerix, Inc. (Durham, North Carolina); The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | John Henry Bougher, III (Durham, North Carolina); Ramamurty V S Changalvala (Durham, North Carolina); Aaron Leigh Downey (Durham, North Carolina); John C. Drach (Ann Arbor, Michigan); Ernest Randall Lanier, Jr. (Durham, North Carolina); Andrew Louis McIver (Durham, North Carolina); Bradley David Robertson (Durham, North Carolina); Dean Wallace Selleseth (Durham, North Carolina); Phiroze Behram Sethna (Durham, North Carolina); Leroy Townsend (Ann Arbor, Michigan); Roy W. Ware (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides pyrrolopyrimidine nucleoside analogs of the Formula I, Formula IA, Formula IB, or Formula II and phospholipid conjugates and pharmaceutical compositions thereof wherein Rc and A are defined herein. Also presented are methods of treating and/or preventing viral infection and/or viral infection-associated disease or disorder with one or more compounds of Formula I, Formula IA, Formula IB, or Formula II. |
| FILED | Wednesday, January 27, 2021 |
| APPL NO | 17/159451 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/706 (20130101) A61K 31/7052 (20130101) A61K 31/7064 (20130101) Heterocyclic Compounds C07D 239/70 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/14 (20130101) Original (OR) Class C07H 19/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981702 | Purse et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | San Diego State University Research Foundation (San Diego, California) |
| ASSIGNEE(S) | San Diego State University (SDSU) Foundation (San Diego, California) |
| INVENTOR(S) | Byron W. Purse (San Diego, California); Dillon Burns (San Diego, California); Kristine Teppang (San Diego, California); Raymond Lee (San Diego, California); Melissa Lokensgard (San Diego, California) |
| ABSTRACT | Herein reported are new tricyclic cytidine compounds, such as 8-diethylamino-tC (8-DEA-tC), that respond to DNA and/or RNA duplex formation with up to a 20-fold increase in fluorescent quantum yield as compared with the free nucleoside, depending on neighboring bases. This turn-on response to duplex formation is by far the greatest of any reported nucleoside analogue that can participate in Watson-Crick base pairing. Measurements of the quantum yield of 8-DEA-tC mispaired with adenosine and, separately, opposite an abasic site show that there is almost no fluorescence increase without the formation of correct Watson-Crick hydrogen bonds. Kinetic isotope effects from the use of deuterated buffer show that the duplex protects 8-DEA-tC against quenching by excited state proton transfer. DFT calculations provide a rationale for the observed photophysical properties that is dependent on duplex integrity and the electronic structure of the analogue. |
| FILED | Tuesday, September 13, 2022 |
| APPL NO | 17/943682 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/24 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1018 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/77 (20130101) G01N 2021/7786 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981704 | MacMillan et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | David MacMillan (Princeton, New Jersey); Daniel Novoa (New York, New York); Stefan McCarver (Princeton, New Jersey) |
| ABSTRACT | Synthetic methods are described herein operable to efficiently produce a wide variety of molecular species through conjugate additions via decarboxylative mechanisms. For example, methods of functionalization of peptide residues are described, including selective functionalization of peptide C-terminal residues. In one aspect, a method of peptide functionalization comprises providing a reaction mixture including a Michael acceptor and a peptide and coupling the Michael acceptor with the peptide via a mechanism including decarboxylation of a peptide reside. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/469102 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/181 (20130101) B01J 31/1815 (20130101) B01J 35/004 (20130101) B01J 2231/324 (20130101) B01J 2231/348 (20130101) B01J 2531/827 (20130101) B01J 2540/12 (20130101) B01J 2540/22 (20130101) B01J 2540/225 (20130101) Peptides C07K 1/107 (20130101) C07K 1/113 (20130101) Original (OR) Class C07K 5/0205 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/29 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981707 | Kwong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter D. Kwong (Washington, District of Columbia); Barney S. Graham (Smyrna, Georgia); Jason S. McLellan (Austin, Texas); Jeffrey Boyington (Clarksburg, Maryland); Lei Chen (Rockville, Maryland); Man Chen (Clarksburg, Maryland); Gwo-Yu Chuang (Rockville, Maryland); Ivelin Stefanov Georgiev (Nashville, Tennessee); Jason Gorman (Silver Spring, Maryland); Michael Gordon Joyce (Washington, District of Columbia); Masaru Kanekiyo (North Bethesda, Maryland); Gilad Ofek (Gaithersburg, Maryland); Marie Pancera (Seattle, Washington); Mallika Sastry (Rockville, Maryland); Cinque Soto (Rockville, Maryland); Sanjay Srivatsan (Lilburn, Georgia); Guillaume Stewart-Jones (Cambridge, Massachusetts); Yongping Yang (Potomac, Maryland); Baoshan Zhang (Bethesda, Maryland); Tongqing Zhou (Boyds, Maryland) |
| ABSTRACT | Disclosed are Respiratory Syncytial Virus (RSV) antigens including a recombinant RSV F protein stabilized in a prefusion conformation. Also disclosed are nucleic acids encoding the antigens and methods of producing the antigens. Methods for generating an immune response in a subject are also disclosed. In some embodiments, the method is a method for treating or preventing a RSV infection in a subject by administering a therapeutically effective amount of the antigen to the subject. |
| FILED | Monday, September 11, 2023 |
| APPL NO | 18/464786 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/155 (20130101) A61K 2039/53 (20130101) A61K 2039/543 (20130101) A61K 2039/5252 (20130101) A61K 2039/5254 (20130101) A61K 2039/55505 (20130101) A61K 2039/55561 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/21 (20130101) C07K 2319/22 (20130101) C07K 2319/50 (20130101) C07K 2319/70 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10343 (20130101) C12N 2760/18522 (20130101) C12N 2760/18534 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981708 | Malley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Richard Malley (Beverly, Massachusetts); Yingjie Lu (West Roxbury, Massachusetts); Fan Zhang (West Roxbury, Massachusetts) |
| ABSTRACT | The present embodiments provide for an immunogenic multiple antigen presenting system comprising a polymer to which antigens are associated by complementary affinity molecules. For example, the polymer can be a polysaccharide, or antigenic polysaccharide, to which protein or peptide antigens from the same or different pathogens are indirectly linked. The present immunogenic compositions can elicit both humoral and cellular immune responses to one or multiple antigens at the same time. |
| FILED | Friday, July 31, 2020 |
| APPL NO | 16/945714 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/092 (20130101) A61K 39/385 (20130101) A61K 47/61 (20170801) A61K 47/543 (20170801) A61K 47/557 (20170801) A61K 2039/70 (20130101) A61K 2039/625 (20130101) A61K 2039/627 (20130101) A61K 2039/645 (20130101) A61K 2039/6031 (20130101) A61K 2039/6093 (20130101) A61K 2039/55505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 14/31 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/20 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981714 | Castor et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trevor Percival Castor (Arlington, Massachusetts); Vasudevacharya Jayarama (Framingham, Massachusetts); James A McSwiggen (Boulder, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Trevor Percival Castor (Arlington, Massachusetts); Vasudevacharya Jayarama (Framingham, Massachusetts); James A McSwiggen (Boulder, Colorado) |
| ABSTRACT | The present invention pertains to the nanoencapsulation of siRNA and other biologics in phospholipid nanosomes for the improved delivery of siRNA and other biologics to targeted diseased human or animal organs and human or animal cells and apparatus and methods for making the same. In embodiments of the present invention, novel siRNAs were designed to down regulate CCR5 and CD4, based on an analysis of all known alternative transcripts for each gene from both human and monkey (Macaca mulatta) genomes. Embodiments of the present invention feature supercritical, critical and near critical fluids. Embodiments of the present invention also pertain to down regulation of CXCR4 receptor and targeting of nanosomes containing specific siRNA sequences to cells expressing those receptors on the cell surface by coating them with specific ligands. These include ligands for the receptors CCR5, CD4 and CXCR4. |
| FILED | Thursday, November 12, 2020 |
| APPL NO | 17/096738 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Peptides C07K 14/5446 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981752 | Pang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| INVENTOR(S) | Hongbo Pang (La Jolla, California); Erkki Ruoslahti (La Jolla, California) |
| ABSTRACT | Disclosed are compositions and methods useful for targeting molecules to activated macrophages, such as tumor associated macrophages. The compositions and methods are based on peptide sequences, such as AMT peptides, that home to activated macrophages. The disclosed homing to activated macrophages is useful for delivering therapeutic and detectable agents to cells and tissues where immune system effects or inflammation are occurring. |
| FILED | Tuesday, May 01, 2018 |
| APPL NO | 16/607043 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/6911 (20170801) Peptides C07K 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981754 | Popel et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Aleksander S. Popel (Lutherville-Timonium, Maryland); Niranjan B. Pandey (White Marsh, Maryland); Esak Lee (Windsor Mill, Maryland); Jordan J. Green (Nottingham, Maryland); Ron B. Shmueli (Baltimore, Maryland) |
| ABSTRACT | Mimetic peptides having anti-angiogenic and anti-tumorigenic properties and methods of their use for treating cancer, ocular diseases, such as age-related macular degeneration, and other-angiogenesis-dependent diseases are disclosed, More particularly, an isolated peptide comprising the amino acid sequence LRRFSTAPFAFIDINDVINF, which exhibits anti-angiogenic activity in endothelial cell proliferation, migration, adhesion, and tube formation assays, anti-migratory activity in human breast cancer cells in vitro, anti-angiogenic and anti-tumorigenic activity in vivo in breast cancer xenograft models, and age-related macular degeneration models is disclosed. The isolate peptide also exhibits anti-lymphangiogenic and directly anti-tumorigenic properties. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/989416 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/10 (20130101) A61K 45/06 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981760 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado); UNIVERSITY OF NEW HAMPSHIRE (Durham, New Hampshire) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); University of New Hampshire (Durham, New Hampshire) |
| INVENTOR(S) | Jung-Jae Lee (Aurora, Colorado); Kyung Jae Jeong (Durham, New Hampshire) |
| ABSTRACT | The present invention relates to the unexpected discovery of a cross-linked polymer of 2-hydroxyethyl methacrylate and dipicolylamine-containing monomers that can be used as a therapeutic lens to treat ocular diseases or disorders associated with matrix metalloproteinase (MMP) over-activity and/or over-expression, such as but not limited to corneal melting (or keratolysis). |
| FILED | Friday, June 28, 2019 |
| APPL NO | 17/256354 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0051 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Heterocyclic Compounds C07D 213/38 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 20/40 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2333/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981891 | Steemers et al. |
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| FUNDED BY |
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| APPLICANT(S) | Illumina, Inc. (San Diego, California); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | Illumina, Inc. (San Diego, California); University of Washington (Seattle, Washington) |
| INVENTOR(S) | Frank J. Steemers (San Diego, California); Jay Shendure (Seattle, Washington); Yi Yin (Seattle, Washington) |
| ABSTRACT | Provided herein are methods for preparing a sequencing library that includes nucleic acids from a plurality of single cells. In one embodiment, the methods include linear amplification of the nucleic acids. In one embodiment, the sequencing library includes whole genome nucleic acids from the plurality of single cells. In one embodiment, the nucleic acids include three index sequences. Also provided herein are compositions, such as compositions that include the nucleic acids having three index sequences. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 16/415969 |
| ART UNIT | 1675 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1247 (20130101) C12N 15/1003 (20130101) Original (OR) Class Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) C40B 50/06 (20130101) C40B 50/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981892 | Mello et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Craig Cameron Mello (Barrington, Rhode Island); Krishna Sumanth Ghanta (Grafton, Massachusetts); Gregoriy Dokshin (Belmont, Massachusetts); Aamir Mir (Worcester, Massachusetts); Hassan Gneid (Worcester, Massachusetts); Jonathan Kenneth Watts (Worcester, Massachusetts); Erik Joseph Sontheimer (Auburndale, Massachusetts) |
| ABSTRACT | The disclosure provides novel methods and compositions for gene editing. In particular, the disclosure relates to compositions and methods of making modified nucleic acid donor templates for highly efficient and precise gene editing. |
| FILED | Monday, April 15, 2019 |
| APPL NO | 16/384612 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/66 (20130101) C12N 15/102 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 15/902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981895 | Martin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas); Texas Heart Institute (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine and Texas Heart Institute (Houston, Texas) |
| INVENTOR(S) | James F. Martin (Pearland, Texas); Yuka Morikawa (Houston, Texas); Todd Ryan Heallen (Houston, Texas); John Leach (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure include methods and compositions for the renewal of cardiomyocytes by targeting the Hippo pathway. In particular embodiments, an individual with a need for cardiomyocyte renewal is provided an effective amount of a shRNA molecule that targets the Sav1 gene. Particular shRNA sequences are disclosed. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/931270 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/30 (20130101) C12N 2740/15043 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981909 | Anderson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel G. Anderson (Framingham, Massachusetts); Robert Alexander Wesselhoeft (Boston, Massachusetts); Piotr S. Kowalski (Allston, Massachusetts) |
| ABSTRACT | Disclosed are methods and constructs for engineering circular RNA Disclosed is a vector for making circular RNA, said vector comprising the following elements operably connected to each other and arranged in the following sequence: a) a 5′ homology arm, b) a 3′ group I intron fragment containing a 3′ splice site dinucleotide, c) an optional 5′ spacer sequence, d) a protein coding or noncoding region, e) an optional 3′ spacer sequence, f) a 5′ Group I intron fragment containing a 5′ splice site dinucleotide, and g) a 3′ homology arm. This vector allows production of a circular RNA that is translatable or biologically active inside eukaryotic cells. In one embodiment, the vector can comprise the 5′ spacer sequence, but not the 3′ spacer sequence. In yet another embodiment, the vector can also comprise the 3′ spacer sequence, but not the 5′ spacer sequence. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/432177 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 16/2803 (20130101) C07K 2317/31 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 2015/859 (20130101) C12N 2015/8518 (20130101) C12N 2800/70 (20130101) C12N 2800/107 (20130101) C12N 2800/202 (20130101) C12N 2840/55 (20130101) C12N 2840/60 (20130101) C12N 2840/203 (20130101) C12N 2999/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981911 | Chan et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Ying Kai Chan (Cambridge, Massachusetts); George M. Church (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein, in some embodiments, are recombinant viral genomes comprising an inhibitory oligonucleotide that reduces inflammation for use, for example, in gene therapy. |
| FILED | Thursday, November 08, 2018 |
| APPL NO | 16/762356 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/117 (20130101) C12N 2710/10343 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981917 | Church et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Prashant G. Mali (La Jolla, California); Kevin M. Esvelt (Auburndale, Massachusetts) |
| ABSTRACT | Methods of modulating expression of a target nucleic acid in a cell are provided including introducing into the cell a first foreign nucleic acid encoding one or more RNAs complementary to DNA, wherein the DNA includes the target nucleic acid, introducing into the cell a second foreign nucleic acid encoding a nuclease-null Cas9 protein that binds to the DNA and is guided by the one or more RNAs, introducing into the cell a third foreign nucleic acid encoding a transcriptional regulator protein or domain, wherein the one or more RNAs, the nuclease-null Cas9 protein, and the transcriptional regulator protein or domain are expressed, wherein the one or more RNAs, the nuclease-null Cas9 protein and the transcriptional regulator protein or domain co-localize to the DNA and wherein the transcriptional regulator protein or domain regulates expression of the target nucleic acid. |
| FILED | Tuesday, October 25, 2022 |
| APPL NO | 17/972885 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/102 (20130101) C12N 15/113 (20130101) C12N 15/635 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/3513 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981918 | Laperle et al. |
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| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Alexander Laperle (North Hollywood, California); Samuel Sances (Santa Monica, California); Nur Yucer (Los Angeles, California); Clive N. Svendsen (Pacific Palisades, California) |
| ABSTRACT | Induced Pluripotent Stem Cell (Ipsc) technology enables the generation and study of living brain tissue relevant to Parkinson's disease (PD) ex vivo. Utilizing cell lines from PD patients presents a powerful discovery system that links cellular phenotypes observed in vitro with real clinical data. Differentiating patient-derived iPSCs towards a dopaminergic (DA) neural fate revealed that these cells exhibit molecular and functional properties of DA neurons in vitro that are observed to significantly degenerate in the substantia nigra of PD patients. Clinical symptoms that drive the generation of other relevant cell types may also yield novel PD-specific phenotypes in vitro that have the potential to lead to new therapeutic avenues for patients with PD. Due to their early onset and non-familial origin, differentiated nervous tissue from these patients offer a key opportunity to discover neuron subtype-specific pathological mechanisms and importantly interrogate the contribution of their genetic background in susceptibility to PD. |
| FILED | Friday, April 05, 2019 |
| APPL NO | 17/041788 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 2501/13 (20130101) C12N 2501/15 (20130101) C12N 2501/41 (20130101) C12N 2501/119 (20130101) C12N 2501/999 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981923 | Leen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Ann Marie Leen (Houston, Texas); Juan Fernando Vera Valdes (Houston, Texas); Cliona M. Rooney (Houston, Texas); Ulrike Gerdemann (Cambridge, Massachusetts) |
| ABSTRACT | The present invention concerns methods of generating CTLs that are able to target at least one antigen from two or more viruses. The method includes exposing mixtures of peptides for different antigens to the same plurality of PBMCs and, at least in certain aspects, expanding the cells in the presence of IL4 and IL7. |
| FILED | Monday, April 18, 2022 |
| APPL NO | 17/659624 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 2039/57 (20130101) A61K 2039/70 (20130101) A61K 2039/572 (20130101) A61K 2039/577 (20130101) A61K 2039/5158 (20130101) A61K 2039/55527 (20130101) Peptides C07K 14/03 (20130101) C07K 14/11 (20130101) C07K 14/025 (20130101) C07K 14/135 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) Original (OR) Class C12N 7/00 (20130101) C12N 2501/2302 (20130101) C12N 2501/2304 (20130101) C12N 2501/2307 (20130101) C12N 2501/2315 (20130101) C12N 2710/16134 (20130101) C12N 2710/16234 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981931 | Evans et al. |
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| FUNDED BY |
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| APPLICANT(S) | SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Ronald Evans (La Jolla, California); Michael Downes (La Jolla, California); Yasuyuki Kida (La Jolla, California); Teruhisa Kawamura (La Jolla, California); Zong Wei (La Jolla, California); Ruth T. Yu (La Jolla, California); Annette R. Atkins (La Jolla, California) |
| ABSTRACT | The invention generally features compositions comprising induced pluripotent stem cell progenitors (also termed reprogramming progenitor cells) and methods of isolating such cells. The invention also provides compositions comprising induced pluripotent stem cells (iPSCs) derived from such progenitor cells. Induced pluripotent stem cell progenitors generate iPSCs at high efficiency. |
| FILED | Tuesday, December 08, 2020 |
| APPL NO | 17/114888 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) Original (OR) Class C12N 2501/39 (20130101) C12N 2506/02 (20130101) C12N 2506/1307 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981933 | Vogt et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Caleb Darwin Vogt (Minneapolis, Minnesota); Angela Panoskaltsis-Mortari (Woodbury, Minnesota) |
| ABSTRACT | Devices, systems, and techniques are described for printing pre-aligned microtissues into larger tissue constructs. For example, a method of printing a tissue construct includes aligning cells in a first direction to create pre-aligned microtissues, suspending the pre-aligned microtissues in a liquid to create a bioink, and depositing the pre-aligned microtissues in a second direction to create the tissue construct. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 17/446563 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 80/00 (20141201) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0697 (20130101) Original (OR) Class C12N 2502/23 (20130101) C12N 2502/28 (20130101) C12N 2502/1347 (20130101) C12N 2533/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981943 | Mahajan et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Vinit B. Mahajan (Iowa City, Iowa); Alexander G. Bassuk (Iowa City, Iowa); Diana F. Colgan (Iowa City, Iowa); Gabriel Velez (Iowa City, Iowa); Kellie Schaefer (Iowa City, Iowa); Marcus Toral (Iowa City, Iowa); Shu Wu (Iowa City, Iowa); Lokesh Gakhar (Iowa City, Iowa) |
| ABSTRACT | The present disclosure provides CAPN5 substrates and CAPN5 inhibitors, nucleic acids encoding CAPN5 substrates or CAPN5 inhibitors, methods to deliver CAPN5 substrate or CAPN5 inhibitor agents to the eye, and methods of identifying inhibitors of CAPN5. |
| FILED | Monday, October 02, 2017 |
| APPL NO | 16/340657 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/08 (20130101) A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) A61P 29/00 (20180101) Peptides C07K 7/64 (20130101) C07K 14/49 (20130101) C07K 14/81 (20130101) C07K 14/8139 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6472 (20130101) Original (OR) Class Enzymes C12Y 304/22 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981953 | Hull et al. |
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| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Christina Marie Hull (Middleton, Wisconsin); Mingwei Huang (Madison, Wisconsin); Sebastien Claude Ortiz (Madison, Wisconsin) |
| ABSTRACT | A method of testing compounds for activity to inhibit germination of spores. The method includes the steps of providing bacterial, fungal, or plant spores transformed to contain and express a detectable marker, wherein the marker when expressed, is operationally linked to a spore-specific or yeast-specific protein, in a medium and under environmental conditions in which the spores will germinate, and measuring a first signal output generated by the marker prior to the spores initiating germination; contacting the spores of step (a) with a compound whose activity to inhibit germination of spores is to be measured; incubating the spores of step (b) under environmental conditions and for a time wherein spores not treated with the compound will germinate; and determining extent of germination of the spores by measuring a second signal output generated by the marker, wherein a difference between the first signal output and the second signal output is proportional to the extent of germination of the spores. Also described are compositions of matter for inhibiting spore germination in vitro and in vivo. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/369939 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 33/10 (20130101) A01N 37/44 (20130101) A01N 41/12 (20130101) A01N 47/40 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/24 (20130101) A61K 31/137 (20130101) A61K 31/145 (20130101) A61K 31/155 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/10 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Original (OR) Class C12Q 1/66 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/375 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981956 | Saka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Sinem K. Saka (Cambridge, Massachusetts); Jocelyn Yoshiko Kishi (Cambridge, Massachusetts); Peng Yin (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein, in some embodiments, are compositions and methods for proximity detection of molecular targets. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/964527 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class C12Q 1/6804 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981959 | Ostrer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MORGAN AND MENDEL GENOMICS, INC. (New York, New York); ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Harry Ostrer (New York, New York); Johnny C. Loke (Valley Cottage, New York); Ishraq Alim (New York, New York) |
| ABSTRACT | Heritable pathogenic variants in the mismatch repair (MMR) pathway, also known as Lynch Syndrome (LS), can lead to the development of colon cancer and other cancers. Following mismatch, a complex of proteins consisting of MLH1, MSH2, MSH6 and PMS2 translocate into the nucleus to signal recruitment of repair mechanisms. Flow cytometry-based, functional variant assays (FVAs), were developed to determine whether variants in these MMR repair genes and/or other related genes would augment the nuclear translocation of MLH1 and MSH2 and downstream nuclear phosphorylation of ATM and ATR in response to DNA mismatches. Each assay distinguished pathogenic variants in MMR repair genes (MLH1, MSH2, PMS2 and MSH6) from benign controls. The combination of multiple assays provided robust separation between heterozygous pathogenic variant carriers and benign controls. The ability to produce distinct molecular phenotypes by these assays suggest FVA assays of MMR pathways could be used to identify LS and associated risk of colon and other cancers and could act as an adjunct to MMR gene sequencing panels in categorizing variants. |
| FILED | Thursday, May 19, 2022 |
| APPL NO | 17/748522 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6827 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/14 (20130101) G01N 33/5023 (20130101) G01N 33/5035 (20130101) G01N 33/5041 (20130101) G01N 33/57419 (20130101) G01N 33/57484 (20130101) G01N 2015/1006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982610 | Demirci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Utkan Demirci (Cambridge, Massachusetts); Waseem Asghar (Boston, Massachusetts) |
| ABSTRACT | A system and method for sorting sperm is provided. The system includes a housing and a microfluidic system supported by the housing. The system also includes an inlet providing access to the microfluidic system to deliver sperm to the microfluidic system and an outlet providing access to the microfluidic system to harvest sorted sperm from the microfluidic system. The microfluidic system provides a flow path for sperm from the inlet to the outlet and includes at least one channel extending from the inlet to the outlet to allow sperm delivered to the microfluidic system through the inlet to progress along the flow path toward the outlet. The microfluidic system also includes a filter including a first plurality of micropores arranged in the flow path between the inlet and the outlet to cause sperm traveling along the flow path to move against through the filter and gravity to reach the outlet. |
| FILED | Friday, September 22, 2023 |
| APPL NO | 18/371952 |
| ART UNIT | 1799 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/061 (20130101) C12N 5/0612 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4005 (20130101) G01N 15/00 (20130101) G01N 15/10 (20130101) Original (OR) Class G01N 2001/4088 (20130101) G01N 2015/0003 (20130101) G01N 2015/0065 (20130101) G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) G01N 2800/367 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982611 | Cho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NANOCELLECT BIOMEDICAL, INC. (San Diego, California) |
| ASSIGNEE(S) | NANOCELLECT BIOMEDICAL, INC. (San Diego, California) |
| INVENTOR(S) | Sunghwan Cho (San Diego, California); Jose Manuel Morachis (San Diego, California); Ivan Gagne (San Diego, California); Rick Segil (San Diego, California); William Arthur Alaynick (San Diego, California); Zhe Mei (San Diego, California); Sean Phillips (San Diego, California); Chien-Chun Yang (San Diego, California); Dongseob Yun (San Diego, California); Michael Jerome Benchimol (San Diego, California); Manna Doud (San Diego, California); Nicholas Sullivan (San Diego, California); Constance Ardila (San Diego, California) |
| ABSTRACT | A method includes providing a cartridge and the cartridge includes a slot for receiving a microfluidic chip having a set of first channels. The cartridge also includes a set of second channels and each channel of the set of second channels is coupleable to a different channel of the set of first channels during use with the microfluidic chip. The cartridge also includes an indent configured for engagement and alignment of the cartridge during use. The method also includes inserting the cartridge into a device, such that the cartridge engages a first biasing member of the device configured for alignment of the cartridge in a first direction. The first biasing member is configured to bias movement of the cartridge into locking position with a notch of the device. |
| FILED | Tuesday, March 20, 2018 |
| APPL NO | 16/495738 |
| ART UNIT | 3653 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502746 (20130101) B01L 3/502761 (20130101) B01L 2200/0652 (20130101) B01L 2300/0819 (20130101) B01L 2400/082 (20130101) Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 5/342 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/149 (20240101) G01N 15/1425 (20130101) Original (OR) Class G01N 15/1484 (20130101) G01N 2015/1006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982615 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Ji-Xin Cheng (Newton, Massachusetts); Lu Lan (Allston, Massachusetts); Jiaze Yin (Waltham, Massachusetts) |
| ABSTRACT | Systems and methods are provided for performing photothermal dynamic imaging. An exemplary method includes: scanning a sample to produce a plurality of raw photothermal dynamic signals; receiving the raw photothermal dynamic signals of the sample; generating a plurality of second signals by matched filtering the raw photothermal dynamic signals to reject non-modulated noise; and performing an inverse operation on the second signals to retrieve at least one thermodynamic signal in a temporal domain. |
| FILED | Tuesday, March 28, 2023 |
| APPL NO | 18/127388 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/35 (20130101) G01N 21/47 (20130101) G01N 21/171 (20130101) Original (OR) Class G01N 2021/3595 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982622 | Fereidouni et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Farzad Fereidouni (Sacramento, California); Richard M. Levenson (Davis, California) |
| ABSTRACT | During operation of the system, a sample of the biological material is placed against a surface of a waveguide, which is comprised of a UV-transparent waveguide material. Then, the system launches UV light from a UV light source via side-illumination into an input end of the waveguide, wherein a launch angle for components of the UV light is greater than a critical angle between the waveguide material and air, so that the UV light propagates through the waveguide via total internal reflection to reach the sample. The launch angle is also less than a critical angle between the waveguide material and the sample, so that when the UV light reaches the sample, the UV light escapes the waveguide through refraction to illuminate the sample. Finally, an imaging mechanism located on an opposite side of the waveguide from the sample captures an image of the illuminated sample. |
| FILED | Friday, August 18, 2023 |
| APPL NO | 18/452437 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 9/52 (20130101) B01L 2300/021 (20130101) B01L 2300/0822 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 1/36 (20130101) G01N 1/312 (20130101) G01N 21/6428 (20130101) G01N 21/6458 (20130101) Original (OR) Class G01N 2021/6439 (20130101) Optical Elements, Systems, or Apparatus G02B 1/14 (20150115) G02B 6/0038 (20130101) G02B 6/0065 (20130101) G02B 6/0068 (20130101) G02B 21/06 (20130101) G02B 21/16 (20130101) G02B 21/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982671 | Steere et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Allen C. Steere (Wellesley, Massachusetts); Elise E. Drouin (Boston, Massachusetts) |
| ABSTRACT | Disclosed herein are methods of diagnosing Rheumatoid arthritis in a subject comprising determining whether the subject is immunologically reactive with P. copri or a portion thereof. In one aspect of the invention the immunological reactivity of the subject to one or more protein of P. copri or polypeptide fragments thereof such as protein Pc-p27 or polypeptide fragments thereof, as compared to an appropriate control, indicates the subject has rheumatoid arthritis. Examples of specific assays, compositions, and kits for use with the methods are also disclosed. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/116260 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1257 (20130101) C07K 2317/34 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/533 (20130101) G01N 33/564 (20130101) Original (OR) Class G01N 33/6878 (20130101) G01N 33/56916 (20130101) G01N 2469/20 (20130101) G01N 2800/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982725 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Xiaoping Wu (Minneapolis, Minnesota); Xiaodong Ma (Minneapolis, Minnesota); Kamil Ugurbil (Minneapolis, Minnesota) |
| ABSTRACT | Magnetic resonance images with improved image quality consistent with those obtained using parallel radio frequency (“RF”) transmission (“pTx”) techniques are generated from data acquired using single transmission hardware (e.g., single channel RF transmission). A deep-learning framework is used to train a deep neural network to convert images obtained with single transmission into pTx-like images. The pTx-like images have reduced signal variations and dropouts that may otherwise be attributable to B1+ inhomogeneities. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734776 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) G06N 3/088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11983868 | Madabhushi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Nathaniel Braman (Cleveland, Ohio); Kavya Ravichandran (Westlake, Ohio); Andrew Janowczyk (East Meadow, New York) |
| ABSTRACT | Embodiments predict response to neoadjuvant chemotherapy (NAC) in breast cancer (BCa) from pre-treatment dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). Embodiments compute, using a machine learning (ML) classifier, a first probability of response based on a set of radiomic features extracted from a tumoral region represented in a pre-treatment DCE-MRI image of a region of tissue (ROT) demonstrating BCa; extract patches from the tumoral region; provide the patches to a convolutional neural network (CNN); receive, from the CNN, a pixel-level localized patch probability of response; compute a second probability of response based on the pixel-level localized patch probability; compute a combined ML probability from the first and second probabilities; compute a final probability of response based on the combined ML probability and clinical information associated with the ROT; classify the ROT as a responder or non-responder based on the final probability of response; and display the classification. |
| FILED | Wednesday, February 20, 2019 |
| APPL NO | 16/280322 |
| ART UNIT | 1672 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/0014 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/454 (20220101) G06V 10/764 (20220101) G06V 10/809 (20220101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 40/00 (20190201) G16B 50/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984553 | Visco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California); Vitaliy Nimon (San Francisco, California) |
| ABSTRACT | A lithium ion-conductive solid electrolyte including a freestanding inorganic vitreous sheet of sulfide-based lithium ion conducting glass is capable of high performance in a lithium metal battery. Such an electrolyte is also manufacturable, and readily adaptable for battery cell and cell component manufacture, in a cost-effective, scalable manner using an automated machine based system, apparatus and methods based on inline spectrophotometry to assess and inspect the quality of such vitreous solid electrolyte sheets and associated components. Suitable manufacturing methods can involve multi-stage thinning of a sulfide glass preform that includes a first thinning operation that involves applying a compressive force onto the preform to form a glass sheet and a second thinning operation that involves applying a tensile force on the as-formed glass sheet (e.g., drawing the sheet by pulling). |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 16/721787 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) G01N 21/896 (20130101) G01N 2021/8967 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/0407 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 10/0566 (20130101) H01M 50/46 (20210101) H01M 50/406 (20210101) H01M 50/437 (20210101) H01M 50/497 (20210101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11980553 | Perry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| ASSIGNEE(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| INVENTOR(S) | N. Christopher Perry (Manchester, New Hampshire); Keith D. Violette (Sandown, New Hampshire); Grant A. Peret (Bedford, New Hampshire); David D. B. Cannan (Manchester, New Hampshire); Christopher C. Langenfeld (Nashua, New Hampshire); Jacob P. Laplante (Manchester, New Hampshire); Thomas A. Doyon (Manchester, New Hampshire) |
| ABSTRACT | A prosthetic device. The prosthetic device may include a flexure cut and/or a sensor to detect movement in accordance with a degree of movement. In an embodiment, the sensor may be disposed within the flexure cut. Other embodiments include at least one wire configured to connect a sensor located in a distal portion to a proximal portion, while annularly traversing a joint. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/338727 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/50 (20130101) A61F 2/54 (20130101) A61F 2/70 (20130101) A61F 2/76 (20130101) Original (OR) Class A61F 2/586 (20130101) A61F 2002/704 (20130101) A61F 2002/5072 (20130101) A61F 2002/6863 (20130101) A61F 2002/7615 (20130101) A61F 2002/7635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980561 | Fay |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Department of Defense (Silver Spring, Maryland) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF DEFENSE (Bethesda, Maryland) |
| INVENTOR(S) | Jeffrey G Fay (Silver Spring, Maryland) |
| ABSTRACT | An orthotic device including a plurality of posterior dynamic struts and an adjustable posterior multiple strut engager, wherein the plurality of posterior dynamic struts has a first posterior dynamic strut and one or more additional posterior dynamic struts, and wherein the adjustable posterior multiple strut engager is affixed to the first posterior dynamic strut and is adapted to restrain the movement of said one or more additional posterior dynamic struts, and wherein the adjustable posterior multiple strut engager may be adjusted to engage said one or more additional posterior dynamic struts in combination with the first posterior dynamic strut, thereby forming a single posterior dynamic strut assembly of greater rigidity than the first posterior dynamic strut alone. |
| FILED | Tuesday, April 11, 2017 |
| APPL NO | 15/484672 |
| ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/0127 (20130101) Original (OR) Class A61F 2005/0137 (20130101) A61F 2005/0167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980640 | Qin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Haiying Qin (Potomac, Maryland); Crystal L Mackall (Stanford, California); Terry J. Fry (Bethesda, Maryland) |
| ABSTRACT | An embodiment of the invention provides bicistronic chimeric antigen receptor (CAR) amino acid constructs. Nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions relating to the CAR constructs are disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed. Methods of making the CAR constructs are disclosed. |
| FILED | Tuesday, May 15, 2018 |
| APPL NO | 16/613187 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/395 (20130101) C07K 14/7051 (20130101) C07K 16/2803 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980641 | Ingber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Donald E. Ingber (Boston, Massachusetts); Samira Musah (Malden, Massachusetts) |
| ABSTRACT | Embodiments of various aspects described herein relate to methods, kits, and cell culture media for generation of podocytes from pluripotent stem (PS) cells, as well as cells produced by the same, and methods of use. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366827 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/22 (20130101) Original (OR) Class A61K 35/545 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0686 (20130101) C12N 2501/16 (20130101) C12N 2501/155 (20130101) C12N 2501/165 (20130101) C12N 2501/385 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) C12N 2533/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980759 | Irazoqui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Pedro Irazoqui (Lafayette, Indiana); Gabriel Omar Albors (West Lafayette, Indiana); Daniel Pederson (Lafayette, Indiana); Christopher John Quinkert (Dyer West Lafayette, Indiana); Muhammad Abdullah Arafat (West Lafayette, Indiana); Jack Williams (Lafayette, Indiana); Zhi Wang (West Lafayette, Indiana); John G. R. Jefferys (Oxford, United Kingdom); Thelma Anderson Lovick (Birmingham, United Kingdom); Terry L. Powley (West Lafayette, Indiana); Rebecca Anne Bercich (Terre Haute, Indiana); Henry Mei (Vadnais Heights, Minnesota); Jesse Paul Somann (West Lafayette, Indiana); Quan Yuan (West Lafayette, Indiana); Hansraj Singh Bhamra (San Jose, California) |
| ABSTRACT | Systems and techniques for wireless implantable devices, for example implantable biomedical devices employed for biomodulation. Some embodiments include a biomodulation system including a non-implantable assembly including a source for wireless power transfer and a data communications system, an implantable assembly including a power management module configured to continuously generate one or more operating voltage for the implantable assembly using wireless power transfer from the non-implantable assembly, a control module operably connected to at least one communication channel and at least one stimulation output, the control module including a processor unit to process information sensed via the at least one communication channel and, upon determining a condition exists, to generate an output to trigger the generation of a stimulus. |
| FILED | Monday, December 12, 2022 |
| APPL NO | 18/079716 |
| ART UNIT | 3796 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/08 (20130101) A61B 5/14539 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) A61N 1/0534 (20130101) A61N 1/0548 (20130101) A61N 1/0551 (20130101) A61N 1/3605 (20130101) A61N 1/3611 (20130101) A61N 1/3787 (20130101) A61N 1/36007 (20130101) A61N 1/36053 (20130101) A61N 1/36064 (20130101) A61N 1/36135 (20130101) Original (OR) Class A61N 1/37211 (20130101) A61N 1/37223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981091 | Wettermark |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Composite Design Sweden AB (Arlöv, Sweden) |
| ASSIGNEE(S) | EOVIDAR AB (Arlov, Sweden) |
| INVENTOR(S) | Fredrik Wettermark (Limhamn, Sweden) |
| ABSTRACT | A method for producing a product including a composite fiber part and a second part, wherein the second part includes a carrier part, wherein the carrier part is a replica of a press tool configured to be heated and to apply a pressure, the method including applying, in a non-cured state, the composite fiber part on the carrier part, arranging the carrier part including the composite fiber part on the press tool, curing the composite fiber part on the carrier part, and removing the product from the press tool, wherein after removal from the press tool the composite fiber part and the carrier part constitutes together at least a part of the finished product. Also disclosed is a composite fiber product including a composite fiber part and a second part. |
| FILED | Tuesday, February 12, 2019 |
| APPL NO | 16/976209 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/30 (20130101) B29C 70/46 (20130101) Original (OR) Class B29C 70/68 (20130101) B29C 70/462 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/32 (20130101) B29L 2031/3041 (20130101) Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion B60B 5/02 (20130101) B60B 7/0013 (20130101) B60B 21/00 (20130101) B60B 2310/52 (20130101) B60B 2310/314 (20130101) B60B 2360/3412 (20130101) B60B 2360/3416 (20130101) B60B 2360/3418 (20130101) B60B 2900/113 (20130101) B60B 2900/115 (20130101) Windows, Windscreens, Non-fixed Roofs, Doors, or Similar Devices for Vehicles; Removable External Protective Coverings Specially Adapted for Vehicles B60J 5/0413 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981377 | Langston et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Tye Langston (Lynn Haven, Florida); Dane Maglich (Panama City Beach, Florida) |
| ABSTRACT | An endless track drive that can be coupled to a vehicle includes a plurality of track feet wherein each track foot is adapted to periodically contact a surface on which the vehicle is to travel as the endless track drive is rotated. At least one spring is coupled to each track foot. The spring(s) apply a biasing force to the track foot that positions the track foot in a neutral position relative to the endless track drive when the track foot is not in contact with the surface. The biasing force is less than a frictional force experienced by the track foot when the track foot is in contact with the surface. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/471398 |
| ART UNIT | 3611 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Motor Vehicles; Trailers B62D 55/06 (20130101) B62D 55/265 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981421 | Fasel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Hermann F. Fasel (Tucson, Arizona); Christoph Hader (Tucson, Arizona) |
| ABSTRACT | A system and method for controlling boundary layer transition for a high-speed vehicle are disclosed. The method includes determining a location of onset of boundary-layer transition that naturally develops during high-speed flight of the high-speed vehicle, and providing a pair of flow control strips at a surface/wall/skin of the high-speed vehicle such that the boundary-layer transition is delayed or prevented during high-speed flight of the high-speed vehicle. The delayed or prevented locations of the transition result in a change in the high-speed boundary layer during the high-speed flight of the high-speed vehicle. The change in the high-speed boundary layer transition affects skin friction drag, aero-thermodynamic heating, and pressure fluctuations in the boundary layer of the high-speed vehicle. |
| FILED | Thursday, December 24, 2020 |
| APPL NO | 17/134047 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 21/04 (20130101) B64C 21/06 (20130101) B64C 23/005 (20130101) Original (OR) Class B64C 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981678 | Schiltz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Gary E. Schiltz (Naperville, Illinois); Jindan Yu (Evanston, Illinois) |
| ABSTRACT | Disclosed are compounds that bind to embryonic ectoderm development (EED) protein and proteolysis-targeting chimeric (PROTAC) derivatives thereof that induce degradation of EED. The disclosed compounds may be characterized as substituted [1,2,4]triazolo[4,3-c]pyrimidin-5-amine compounds. The disclosed PROTAC derivatives thereof typically include a first targeting moiety that binds to EED (MEED) which may be derived from the disclosed [1,2,4]triazolo[4,3-c]pyrimidin-5-amine compounds that bind to EED. The first targeting moiety typically is linked via a bond or a linker (L) to a second targeting moiety that binds to an E3 ubiquitin ligase (ME3). As such, the disclosed PROTACS may be described as having a formula MEED-L-ME3 or ME3-L-MEED, wherein MEED has a formula of where R2, n, and x are as described herein. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 17/733752 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981752 | Pang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| INVENTOR(S) | Hongbo Pang (La Jolla, California); Erkki Ruoslahti (La Jolla, California) |
| ABSTRACT | Disclosed are compositions and methods useful for targeting molecules to activated macrophages, such as tumor associated macrophages. The compositions and methods are based on peptide sequences, such as AMT peptides, that home to activated macrophages. The disclosed homing to activated macrophages is useful for delivering therapeutic and detectable agents to cells and tissues where immune system effects or inflammation are occurring. |
| FILED | Tuesday, May 01, 2018 |
| APPL NO | 16/607043 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/6911 (20170801) Peptides C07K 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981909 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel G. Anderson (Framingham, Massachusetts); Robert Alexander Wesselhoeft (Boston, Massachusetts); Piotr S. Kowalski (Allston, Massachusetts) |
| ABSTRACT | Disclosed are methods and constructs for engineering circular RNA Disclosed is a vector for making circular RNA, said vector comprising the following elements operably connected to each other and arranged in the following sequence: a) a 5′ homology arm, b) a 3′ group I intron fragment containing a 3′ splice site dinucleotide, c) an optional 5′ spacer sequence, d) a protein coding or noncoding region, e) an optional 3′ spacer sequence, f) a 5′ Group I intron fragment containing a 5′ splice site dinucleotide, and g) a 3′ homology arm. This vector allows production of a circular RNA that is translatable or biologically active inside eukaryotic cells. In one embodiment, the vector can comprise the 5′ spacer sequence, but not the 3′ spacer sequence. In yet another embodiment, the vector can also comprise the 3′ spacer sequence, but not the 5′ spacer sequence. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/432177 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 16/2803 (20130101) C07K 2317/31 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 2015/859 (20130101) C12N 2015/8518 (20130101) C12N 2800/70 (20130101) C12N 2800/107 (20130101) C12N 2800/202 (20130101) C12N 2840/55 (20130101) C12N 2840/60 (20130101) C12N 2840/203 (20130101) C12N 2999/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981956 | Saka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Sinem K. Saka (Cambridge, Massachusetts); Jocelyn Yoshiko Kishi (Cambridge, Massachusetts); Peng Yin (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein, in some embodiments, are compositions and methods for proximity detection of molecular targets. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/964527 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class C12Q 1/6804 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982079 | Foltz |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Lee Foltz (Indian Head, Maryland) |
| ABSTRACT | An exemplary axial joint includes a planar member having a first plurality of joined sections and a second plurality of joined sections perpendicular to the first plurality of joined sections. Each section of the first plurality of joined sections and the second plurality of joined sections has a pattern of apertures therein, and each section is foldable approximately perpendicular to an adjacent section. The pattern of apertures in a first section after folding is congruent with the pattern of apertures in a second section after folding, wherein the second section is parallel to the first section, after folding. An elongate member is arranged through the apertures of one or more sections of the planar member, after folding the sections of the planar member. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/602375 |
| ART UNIT | RD00 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/1912 (20130101) Original (OR) Class E04B 2001/1927 (20130101) E04B 2001/1933 (20130101) E04B 2001/1936 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 7/00 (20130101) Blasting F42D 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982297 | Curran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | US Gov't, As represented by the Secretary of the Army (, None) |
| INVENTOR(S) | Kevin Curran (Madison Township, Pennsylvania); Mikael Mead (Clifford Township, Pennsylvania); Raymond Kerby (Stroudsburg, Pennsylvania) |
| ABSTRACT | A tester that can be quickly and easily connected and/or disconnected to a device is described. The tester can check for leaks in the device. The tester can provide a conduit for fluid to flow to the device and a flow meter reading can demonstrate that the device has leakage or no leakage. |
| FILED | Thursday, November 16, 2017 |
| APPL NO | 15/814442 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 19/005 (20130101) Original (OR) Class F15B 19/007 (20130101) F15B 2211/855 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/007 (20130101) G01M 3/26 (20130101) G01M 3/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982358 | Coretto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | August M. Coretto (Windsor, Connecticut); Scott W. Simpson (Feeding Hills, Massachusetts); Donald E. Army (Enfield, Connecticut); Peter J. Dowd (Granby, Connecticut); David J. Zawilinski (W. Granby, Connecticut) |
| ABSTRACT | An inline valve includes a sliding piston having a radially outer stop portion with a forward end. A radially inner sliding portion is connected to the radially outer stop portion by an arm. A housing includes an outer housing body surrounding the piston. The housing has a stop surface selectively in contact with the forward end of the radially outer stop portion of the piston to block flow for a housing inlet to a housing outlet. The radially inner sliding portion slides on a support tube. At least a portion of the radially inner sliding portion is formed of a first material having better wear resistance than a second material forming the outer stop portion of the piston. The second material has a greater resistance to high temperature and pressure than the first material. A vent valve for a compressor is also disclosed. |
| FILED | Friday, October 22, 2021 |
| APPL NO | 17/508485 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Non-positive-displacement Pumps F04D 27/023 (20130101) F04D 27/0215 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 1/126 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982643 | Giurgiutiu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Victor Giurgiutiu (Columbia, South Carolina); Robin James (Columbia, South Carolina); Roshan Joseph (Columbia, South Carolina) |
| ABSTRACT | Employing methodologies and systems to detect damage initiation and growth inside a composite material (matrix cracking, delamination, fiber break, fiber pullout, etc.) wherein damage produces high-frequency acoustic emission (AE) waves that are transported to recording sensors along with relatively lower frequency waves representing the flexural deformation of the impacted composite structure. |
| FILED | Monday, November 23, 2020 |
| APPL NO | 17/101049 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/14 (20130101) Original (OR) Class G01N 29/22 (20130101) G01N 29/4472 (20130101) G01N 2291/0231 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982648 | Lobkis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Etegent Technologies, Ltd. (Cincinnati, Ohio) |
| ASSIGNEE(S) | Etegent Technologies, Ltd. (Cincinnati, Ohio) |
| INVENTOR(S) | Oleg Lobkis (Mason, Ohio); Richard A. Roth (Goshen, Ohio); Christopher G. Larsen (Cincinnati, Ohio); Stuart J. Shelley (Cincinnati, Ohio) |
| ABSTRACT | An environmental condition may be measured with a sensor (10) including a wire (20) having an ultrasonic signal transmission characteristic that varies in response to the environmental condition by sensing ultrasonic energy propagated through the wire using multiple types of propagation, and separating an effect of temperature on the wire from an effect of strain on the wire using the sensed ultrasonic energy propagated through the wire using the multiple types of propagation. A positive feedback loop may be used to excite the wire such that strain in the wire is based upon a sensed resonant frequency, while a square wave with a controlled duty cycle may be used to excite the wire at multiple excitation frequencies. A phase matched cone (200, 210) may be used to couple ultrasonic energy between a waveguide wire (202, 212) and a transducer (204, 214). |
| FILED | Monday, November 30, 2020 |
| APPL NO | 17/107646 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/02 (20130101) F01D 17/08 (20130101) F01D 17/085 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/00 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/10 (20130101) G01L 1/106 (20130101) G01L 1/255 (20130101) G01L 11/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/12 (20130101) G01N 29/326 (20130101) Original (OR) Class G01N 29/2462 (20130101) G01N 2291/0215 (20130101) G01N 2291/0421 (20130101) G01N 2291/0422 (20130101) G01N 2291/0426 (20130101) G01N 2291/0427 (20130101) G01N 2291/02827 (20130101) G01N 2291/02872 (20130101) G01N 2291/02881 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/10 (20130101) G01P 15/097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982906 | Tabirian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Beam Engineering for Advanced Measurements Co. (Orlando, Florida) |
| ASSIGNEE(S) | Beam Engineering for Advanced Measurements Co. (Orlando, Florida) |
| INVENTOR(S) | Nelson V. Tabirian (Winter Park, Florida); David E. Roberts (Apopka, Florida) |
| ABSTRACT | Diffractive optical structures, lenses, waveplates, devices, systems, and methods, which have the same effect on light regardless of the polarization state of the light, utilizing systems of polarization discriminator diffractive waveplate optics and differential polarization converters with special arrangements that do not require introducing spatial separation between the layers. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 17/458761 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/133526 (20130101) G02F 1/133638 (20210101) Original (OR) Class G02F 2201/305 (20130101) G02F 2203/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11983023 | Sterling et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Arlington, Virginia) |
| INVENTOR(S) | Tyler R. Sterling (Bellevue, Washington); Garrett Murdock Myhre (Seattle, Washington); John Robert Lesh (Woodinville, Washington); Thanh Dac Tran (Seattle, Washington) |
| ABSTRACT | Methods systems and apparatuses for reducing or substantially eliminating distortion in a transparent substrate in situ are disclosed. |
| FILED | Monday, January 21, 2019 |
| APPL NO | 16/252998 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 35/0288 (20130101) B29C 51/46 (20130101) B29C 51/421 (20130101) B29C 71/02 (20130101) B29C 73/34 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/10 (20130101) B29K 2105/256 (20130101) B29K 2995/0026 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/778 (20130101) B29L 2031/3052 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 17/10963 (20130101) B32B 2309/025 (20130101) B32B 2369/00 (20130101) Aeroplanes; Helicopters B64C 1/1476 (20130101) B64C 1/1484 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/40 (20170101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 23/005 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 23/22 (20130101) Original (OR) Class G05D 23/27 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 1/0236 (20130101) H05B 3/84 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11983868 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Nathaniel Braman (Cleveland, Ohio); Kavya Ravichandran (Westlake, Ohio); Andrew Janowczyk (East Meadow, New York) |
| ABSTRACT | Embodiments predict response to neoadjuvant chemotherapy (NAC) in breast cancer (BCa) from pre-treatment dynamic contrast enhanced magnetic resonance imaging (DCE-MRI). Embodiments compute, using a machine learning (ML) classifier, a first probability of response based on a set of radiomic features extracted from a tumoral region represented in a pre-treatment DCE-MRI image of a region of tissue (ROT) demonstrating BCa; extract patches from the tumoral region; provide the patches to a convolutional neural network (CNN); receive, from the CNN, a pixel-level localized patch probability of response; compute a second probability of response based on the pixel-level localized patch probability; compute a combined ML probability from the first and second probabilities; compute a final probability of response based on the combined ML probability and clinical information associated with the ROT; classify the ROT as a responder or non-responder based on the final probability of response; and display the classification. |
| FILED | Wednesday, February 20, 2019 |
| APPL NO | 16/280322 |
| ART UNIT | 1672 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/0014 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/454 (20220101) G06V 10/764 (20220101) G06V 10/809 (20220101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 40/00 (20190201) G16B 50/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11983902 | Nussbaum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Matthew Edward Nussbaum (Penn Valley, California); Marissa Sachiko Herron (Annapolis, Maryland) |
| ABSTRACT | A method of classifying terrain, terrain activity and materials through panchromatic imagery a module programmed to provide such classification and aerospace vehicles comprising such module is provided. Panchromatic images of known materials terrains and terrain activities are taken and processed to form a multiband texture cube, that due it amount of data, is stored as a computer data base. New panchromatic images of unclassified materials, terrains and/or terrain activities are processed and compared via computer with such database that allows for inexpensive, quick and efficient classification of such new images. |
| FILED | Tuesday, October 27, 2020 |
| APPL NO | 17/080904 |
| ART UNIT | 2644 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Electric Digital Data Processing G06F 16/55 (20190101) G06F 16/535 (20190101) Image Data Processing or Generation, in General G06T 3/12 (20240101) G06T 3/40 (20130101) G06T 7/97 (20170101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984576 | Tour et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | James M. Tour (Bellaire, Texas); Rodrigo Villegas Salvatierra (Houston, Texas); Duy Xuan Luong (Houston, Texas) |
| ABSTRACT | An electrochemical cell with a lithium-metal anode that suppresses dendrite formation and can be fabricated using a simple, inexpensive, and solvent-free process. The anode is coated with a layer of disordered nanomaterial, saturated with lithium ions, that suppresses dendrite formation during charging. The dendrite-suppression coating can be applied simply using a dry, abrasive technique in which the lithium-metal anode is alternately abraded to roughen the surface and polished using a polishing powder of a material that alloys with the lithium. |
| FILED | Thursday, October 01, 2020 |
| APPL NO | 17/061223 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/043 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/382 (20130101) H01M 4/0402 (20130101) Original (OR) Class H01M 4/628 (20130101) H01M 4/1395 (20130101) H01M 10/052 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984665 | Lipson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF THE COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Michal Lipson (New York, New York); Christoper Thomas Phare (New York, New York); You-Chia Chang (New York, New York); Steven A. Miller (New York, New York) |
| ABSTRACT | An optical apparatus comprising an optical switch array comprising a plurality of optical switches configured to selectively route light through one or more of a plurality of waveguides, a plurality of emitters, wherein at least one emitter of the plurality of emitters is disposed in communication with the one or more of the plurality of waveguides and configured to receive light and cause at least a portion of the light to exit the waveguide, and a lens disposed to receive light exiting the one or more of a plurality of waveguides via the at least one emitter, wherein the lens is configured to direct the received light as an optical output, and wherein the position of the at least one emitter relative to the lens facilitates beam steering of the optical output. |
| FILED | Friday, September 13, 2019 |
| APPL NO | 17/275753 |
| ART UNIT | 2634 — Digital Communications |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/10 (20130101) G01S 17/42 (20130101) G01S 17/89 (20130101) Antennas, i.e Radio Aerials H01Q 3/38 (20130101) Original (OR) Class H01Q 3/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984721 | Siri |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | Kasemsan Siri (Torrance, California) |
| ABSTRACT | An apparatus may include a group of distributed-input series-output (DISO) converters, each of which are actively controlled by a common maximum power tracking (MPT) controller. The common MPT controller is configured to actively control one of the DISO converters in the group of DISO converters to update a present group-peak power voltage of the one DISO converters while remaining DISO converters in the group of DISO converters are controlled to hold most recently grouped peak power voltages updated during their previously non-overlapping uniform time windows of active MPT control. |
| FILED | Thursday, May 13, 2021 |
| APPL NO | 17/319692 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 1/102 (20130101) Original (OR) Class H02J 7/007 (20130101) H02J 2300/26 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11985157 | Lee |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | Richard M. Lee (El Segundo, California) |
| ABSTRACT | Interactive interfaces and data structures representing physical and/or visual information are provided using smart pins (also called “pins” herein). Pins representing vectors of information may be provided. For instance, in the context of cybersecurity, each pin may represent an attack vector that an adversary can use to attack a system. Each pin may have a depth meter and may move up or down according to its value in an operating range. Each pin may also have a color, a number, or both, representing its current value in the operating range. Such pins may provide both a three-dimensional representation of data that is intuitive to users. |
| FILED | Friday, January 24, 2020 |
| APPL NO | 16/751261 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 15/005 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1433 (20130101) Original (OR) Class H04L 63/1441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11985165 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Xu Lin (Chicago, Illinois); Frederico Araujo (White Plains, New York); Teryl Paul Taylor (Danbury, Connecticut) |
| ABSTRACT | A method of detecting deceptive web activity is implemented in an intermediary located between a requesting client device, and a server that hosts a web application. Following a bootstrap phase used to generate a database of information identifying characteristics of clients, the method begins by receiving a page directed to the client from the server. The server injects an invisible DOM element having a set of style properties associated therewith, with one of the set of style properties assigned a random value, to generate a modified page, which is returned to the client. As the client interacts with the modified page, the intermediary tracks the device's styles and uses them to identify the client from information in the database. Once the device is identified, the intermediary then detects whether a spoofing attack has occurred. By leveraging the tracked styles, a spoofing attack on the DOM element's styles may also be detected. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/551563 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/958 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1483 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11985259 | Howard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Jennifer E. Howard (Prosper, Texas); Colby K. Hoffman (Fairview, Texas); Edward Escandon (McKinney, Texas); Albert D. Marzullo (Plano, Texas); Ross MacKinnon (McKinney, Texas); Maegen A. Forrer (Farmersville, Texas) |
| ABSTRACT | A multi-die device a first die containing a plurality of first die signal path elements configured to propagate a stimulus signal and a second die containing a plurality of second die signal path elements configured to propagate the stimulus signal. The multi-die device further includes an interposer configured to establish signal communication between the first die and the second die so as to deliver the stimulus signal from the plurality of first die signal path elements to the plurality of second die signal path elements to generate a propagation delay. The propagation delay is used to generate a single unified PUF response that is indicative of the authenticity of the multi-die device. |
| FILED | Thursday, June 24, 2021 |
| APPL NO | 17/357067 |
| ART UNIT | 2492 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0866 (20130101) H04L 9/3278 (20130101) Original (OR) Class H04L 2209/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11985451 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Donggyu Kim (Cambridge, Massachusetts); Alexander Keesling Contreras (Boston, Massachusetts); Ahmed Omran (Somerville, Massachusetts); Harry Jay Levine (Cambridge, Massachusetts); Hannes Bernien (Somerville, Massachusetts); Mikhail D. Lukin (Cambridge, Massachusetts); Dirk R. Englund (Cambridge, Massachusetts) |
| ABSTRACT | A method of generating uniform large-scale optical focus arrays (LOT As) with a phase spatial light modulator (SLM) includes identifying and removing undesired phase rotation in the iterative Fourier transform algorithm (IFTA), thereby producing computer-generated holograms of highly uniform LOT As using a reduced number of iterations as compared to a weighted Gerchberg-Saxton algorithm. The method also enables a faster compensation of optical system-induced LOT A intensity inhomogeneity than the conventional IFTA. |
| FILED | Friday, February 21, 2020 |
| APPL NO | 17/432723 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/0808 (20130101) G03H 2001/0816 (20130101) Pictorial Communication, e.g Television H04N 9/317 (20130101) H04N 9/3102 (20130101) H04N 9/3138 (20130101) Original (OR) Class H04N 9/3197 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11985895 | Fish |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army DEVCOM, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Michael C. Fish (Arlington, Virginia) |
| ABSTRACT | A thermal energy storage (TES) device includes a thermoelectric cooler; and a metallic phase change material (PCM) within the thermoelectric cooler. The PCM may include any of gallium or its alloys, low temperature fusible alloys, and solid metal shape memory alloys. A thermoelectric effect within the PCM is to transport heat in the thermoelectric cooler. The TES device may include a graded oxide layer adjacent to the PCM to serve as a distributed electrical junction in the thermoelectric cooler to create a hot side thermoelectric junction in a bulk volume of the PCM. The graded oxide layer may include α-IGZO. The TES device may include a high-thermopower corrugated metal foil layer comprising barrier oxides patterned therein. The high-thermopower metal foil layer may be adjacent to the graded oxide layer. The TES device may include a dielectric layer adjacent to the high-thermopower corrugated metal foil layer. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 17/546246 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electric solid-state devices not otherwise provided for H10N 10/13 (20230201) Original (OR) Class H10N 10/17 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11980939 | Paranthaman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Mariappan Parans Paranthaman (Knoxville, Tennessee); Brian K. Post (Knoxville, Tennessee); Brian C. Sales (Lenoir City, Tennessee) |
| ABSTRACT | An electromagnet alignment system for in-situ alignment of a magnetic particulate material is provided. The magnetic particulate material is dispensed through an orifice of a dispensing nozzle used for 3D printing. The system has an electromagnet assembly having a coil. The coil is configured to generate a pulsed magnetic field having a target magnetic flux intensity upon energization of the coil when the magnetic particulate material is being heated and moved through the dispensing nozzle. As a result, the magnetic particulate material is at least partially aligned with respect to a direction by the pulsed magnetic field. The system further includes a power source for implementing the energization of the coil. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/231498 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/10 (20220101) B22F 10/34 (20210101) B22F 10/85 (20210101) B22F 12/13 (20210101) B22F 12/53 (20210101) Original (OR) Class B22F 12/90 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 40/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981169 | Frantzen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Goodyear Tire and Rubber Company (Akron, Ohio) |
| ASSIGNEE(S) | THE GOODYEAR TIRE and RUBBER COMPANY (Akron, Ohio) |
| INVENTOR(S) | Andreas Frantzen (Trier, Germany); Carolin Anna Welter (Schleich, Germany); Anne Therese Peronnet-Paquin (Luxembourg, Luxembourg); Mingliang Du (Copley, Ohio); Stephan Rodewald (Canal Fulton, Ohio); Betul Buehler (Akron, Ohio); Benjamin Isaiah Garn (Norton, Ohio); Daniel Vojtko (Akron, Ohio); Jungmee Kang (Macedonia, Ohio); Dinesh Chandra (Hudson, Ohio) |
| ABSTRACT | A self-inflating tire assembly includes an air tube mounted within a tire sidewall groove. The air tube is in contacting engagement with opposite angled groove surfaces surrounding the air tube. A segment of the air tube is flattened from an expanded diameter to a flat diameter by bending and compression of the groove in a rolling tire footprint to force air evacuated from the flattened segment along a tube air passageway. The sidewall groove extends into an annular, axially extending, sidewall surface such as an axially oriented surface of a tire chafer protrusion located in non-contacting relationship with the rim. The air tube is extruded from a rubber composition, the rubber composition comprising: a diene based rubber; from 0.25 to 5 parts by weight, per 100 parts by weight of rubber (phr), of a self-lubrication agent capable of migrating from the rubber composition to the groove surface and disposing on the groove surface as a liquid; and from 1 to 15 parts by weight, per 100 parts by weight of rubber (phr), of a vulcanization modifier for use in the second rubber composition include α,ω-bis(N,N′-dihydrocarbylthiocarbamamoyldithio)alkanes, bismaleimides, and biscitraconimides. |
| FILED | Wednesday, September 04, 2019 |
| APPL NO | 16/560034 |
| ART UNIT | 3617 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Vehicle Tyres Tyre Inflation; Tyre Changing or Repairing; Repairing, or Connecting Valves To, Inflatable Elastic Bodies in General; Devices or Arrangements Related to Tyres B60C 1/00 (20130101) B60C 13/02 (20130101) B60C 23/123 (20200501) Original (OR) Class B60C 23/135 (20200501) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/00 (20130101) C08K 5/00 (20130101) C08K 5/00 (20130101) C08K 5/00 (20130101) Compositions of Macromolecular Compounds C08L 7/00 (20130101) C08L 7/00 (20130101) C08L 9/00 (20130101) C08L 9/00 (20130101) C08L 9/06 (20130101) C08L 9/06 (20130101) C08L 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981565 | Kauffman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Douglas R Kauffman (Pittsburgh, Pennsylvania); Jonathan W Lekse (Pittsburgh, Pennsylvania); Christopher Mark Marin (Pittsburgh, Pennsylvania); Eric J Popczun (Pittsburgh, Pennsylvania) |
| ABSTRACT | One or more embodiments relates to compositions, method of using and methods of producing a gas mixture. The method includes supplying a composition LaxSryCozMwO3, where x ranges from 0.5 to 1, y ranges 0.0 to 1-x, z ranges from 0.1 to 1.0, and M is a dopant or dopants where w ranges from 0.0 to 1-z; and energizing the composition directly using electromagnetic energy to heat the composition to a temperature above 700° C. The method further includes contacting the composition with a reactant gas mixture comprising methane and an oxidant forming a product gaseous mixture. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/079924 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/83 (20130101) B01J 23/8892 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/40 (20130101) Original (OR) Class C01B 2203/0233 (20130101) C01B 2203/0238 (20130101) C01B 2203/0855 (20130101) C01B 2203/1052 (20130101) C01B 2203/1088 (20130101) C01B 2203/1241 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 51/70 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/77 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981613 | Larsen, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Battelle Savannah River Alliance, LLC (Aiken, South Carolina) |
| INVENTOR(S) | George K. Larsen, III (Aiken, South Carolina); Tyler C. Guin (Aiken, South Carolina); Joseph E. Meany (Atlanta, Georgia); Jay B. Gaillard (Aiken, South Carolina); Mark C. Elvington (Aiken, South Carolina) |
| ABSTRACT | Disclosed are methods and systems for hydrogen isotope exchange of organic molecules that can be carried out with no alteration in the chemical structure of the organic molecules. Methods can be utilized to incorporate a particular hydrogen isotope on an organic molecule (e.g., deuteration or tritiation) or to remove a particular hydrogen isotope from an organic molecule (e.g., detritiation). |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/099455 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 59/00 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 10/007 (20130101) B01J 19/24 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) Original (OR) Class C07B 2200/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981904 | Karlen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); THE UNIVERSITY OF BRITISH COLUMBIA (Vancouver, Canada) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); The University of British Columbia (Vancouver, Canada) |
| INVENTOR(S) | Steven D. Karlen (Madison, Wisconsin); Rebecca Anne Smith (Madison, Wisconsin); John Ralph (Madison, Wisconsin); Emily Beebe (Stoughton, Wisconsin); Craig Bingman (Fitchburg, Wisconsin); Brian Fox (Madison, Wisconsin); Shawn Mansfield (Vancouver, Canada); Heather Mackay (Vancouver, Canada); Hoon Kim (Madison, Wisconsin); Yaseen Mottiar (Vancouver, Canada); Faride Unda (Vancouver, Canada) |
| ABSTRACT | The invention is directed to BAHD acyltransferase enzymes, nucleic acids encoding BAHD acyltransferase enzymes, and inhibitory nucleic acids adapted to inhibit the expression and/or translation of BAHD acyltransferase RNA; expression cassettes, plant cells, and plants that have or encode such nucleic acids and enzymes; and methods of making and using such nucleic acids, enzymes, expression cassettes, cells, and plants. |
| FILED | Friday, November 08, 2019 |
| APPL NO | 17/291932 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1029 (20130101) C12N 15/8223 (20130101) C12N 15/8255 (20130101) Original (OR) Class Enzymes C12Y 203/01196 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981917 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Prashant G. Mali (La Jolla, California); Kevin M. Esvelt (Auburndale, Massachusetts) |
| ABSTRACT | Methods of modulating expression of a target nucleic acid in a cell are provided including introducing into the cell a first foreign nucleic acid encoding one or more RNAs complementary to DNA, wherein the DNA includes the target nucleic acid, introducing into the cell a second foreign nucleic acid encoding a nuclease-null Cas9 protein that binds to the DNA and is guided by the one or more RNAs, introducing into the cell a third foreign nucleic acid encoding a transcriptional regulator protein or domain, wherein the one or more RNAs, the nuclease-null Cas9 protein, and the transcriptional regulator protein or domain are expressed, wherein the one or more RNAs, the nuclease-null Cas9 protein and the transcriptional regulator protein or domain co-localize to the DNA and wherein the transcriptional regulator protein or domain regulates expression of the target nucleic acid. |
| FILED | Tuesday, October 25, 2022 |
| APPL NO | 17/972885 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/102 (20130101) C12N 15/113 (20130101) C12N 15/635 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/3513 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981937 | Vermaas |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Willem Vermaas (Tempe, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Willem Vermaas (Tempe, Arizona) |
| ABSTRACT | The disclosure relates to the production of methyl laurate by genetically engineered photosynthetic microorganisms. In particular, provided herein are methods and compositions for producing methyl laurate from carbon dioxide and water in genetically engineered cyanobacteria and other photosynthetic microorganisms. |
| FILED | Thursday, March 05, 2020 |
| APPL NO | 16/810658 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1007 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/62 (20130101) Enzymes C12Y 201/01015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981946 | Noguera et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Daniel R. Noguera (Madison, Wisconsin); Timothy James Donohue (Middleton, Wisconsin); Jose Perez (Madison, Wisconsin); Wayne S. Kontur (Madison, Wisconsin); German Eduardo Umana Chapeton (Madison, Wisconsin) |
| ABSTRACT | Recombinant microorganisms configured for enhanced production of compounds such as 2-pyrone-4,6-dicarboxylic acid (PDC) and methods of using the recombinant microorganisms for the production of these compounds. The recombinant microorganisms include one or more modifications that reduce 2-pyrone-4,6-dicarboxylic acid (PDC) hydrolase activity, 4-carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate (CHMOD) cis-trans isomerase activity, 4-carboxy-2-hydroxy-6-methoxy-6-oxohexa-2,4-dienoate (CHMOD) methyl esterase activity, and/or vanillate/3-O-methylgallate O-demethylase activity. The recombinant microorganisms can be used to generate PDC from media comprising plant-derived phenolics, such as syringyl phenolics, guaiacyl phenolics, and p-hydroxyphenyl phenolics. The plant-derived phenolics can be derived from pretreated lignin, including depolymerized lignin or other chemically altered lignin. |
| FILED | Thursday, May 06, 2021 |
| APPL NO | 17/313675 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/18 (20130101) C12N 9/90 (20130101) C12N 9/1007 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/06 (20130101) Original (OR) Class Enzymes C12Y 301/01057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982130 | Kontras |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Evan A. Kontras (Kansas City, Missouri) |
| ABSTRACT | A shrouded screw apparatus includes an outer tube, a telescoping inner tube, an auger bit, and an anti-rotation pin. The outer tube has a first sidewall defining a first interior chamber. The first sidewall has an opening defined therethrough. The inner tube is positioned in the first interior chamber. The inner tube has a second sidewall defining a second interior chamber. The second sidewall has a longitudinal groove defined therein. The inner tube is configured to extend from and retract within the first interior chamber of the outer tube. The auger bit is positioned in the second interior chamber and is rotatably coupled to the inner tube. The anti-rotation pin is coupled to the first sidewall of the outer tube and extends inwardly into the first interior chamber. The pin engages the longitudinal groove of the inner tube. |
| FILED | Wednesday, June 15, 2022 |
| APPL NO | 17/841401 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 10/22 (20130101) E21B 10/44 (20130101) E21B 10/62 (20130101) E21B 11/005 (20130101) Original (OR) Class E21B 17/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982499 | Turney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Joseph E. Turney (Amston, Connecticut); Kathryn L. Kirsch (Manchester, Connecticut); Robert H. Dold (Monson, Massachusetts); Matthew B. Kennedy (Vernon, Connecticut) |
| ABSTRACT | A heat exchanger includes a plurality of longitudinally-extending first channels and a plurality of second channels fluidly isolated from the plurality of first channels. Each first channels includes a plurality of spiraling internal fins and a plurality of external fins. The internal fins extend from and are integrally formed with the internal walls of the first channel. The external fins connect extend from and are integrally formed with the external walls of the first channels, connecting channels together. The plurality of second channels is defined in part by external walls of the plurality of first channels and the plurality of external fins. |
| FILED | Friday, August 05, 2022 |
| APPL NO | 17/881731 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/42 (20130101) Original (OR) Class F28F 2001/428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982624 | Houk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Battelle Savannah River Alliance, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Amanda L. Houk (Aiken, South Carolina); Matthew S. Wellons (Aiken, South Carolina); Ross J. Smith (North Augusta, South Carolina); Joshua T. Hewitt (Standardsville, Virginia) |
| ABSTRACT | Carbon fiber characterization processes are described that include multi-condition Raman spectroscopy-based examination combined with multivariate data analyses. Methods are a nondestructive material characterization approach that can provide predictions as to carbon fiber bulk physical properties, as well as identification of unknown carbon fiber materials for quality control purposes. The framework of the multivariate analysis methods includes a principal component-based identification protocol including comparison of Raman spectral data from an unknown carbon fiber with a data library of multiple principal component spaces. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/079609 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/12 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/4412 (20130101) G01J 2003/283 (20130101) G01J 2003/2869 (20130101) G01J 2003/2873 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982684 | Ziatdinov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Maxim A. Ziatdinov (Oak Ridge, Tennessee); Kevin Roccapriore (Oak Ridge, Tennessee); Yongtao Liu (Oak Ridge, Tennessee); Kyle P. Kelley (Oak Ridge, Tennessee); Rama K. Vasudevan (Oak Ridge, Tennessee); Jacob D. Hinkle (Oak Ridge, Tennessee); Sergei V. Kalinin (Knoxville, Tennessee) |
| ABSTRACT | Systems, methods and programs are provided for automated science experiments which use a model with learnt model parameters to define points for physical-characteristic measurements once the model is trained. The systems, methods and programs use active learning which enables describing a relationship between local features of sample-surface structure shown in image patches and determined representations of physical-characteristic measurements. |
| FILED | Friday, May 26, 2023 |
| APPL NO | 18/324343 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/10 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 21/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982979 | Cavraro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Guido Cavraro (Arvada, Colorado); Andrey Bernstein (Golden, Colorado); Manish Kumar Singh (Minneapolis, Minnesota) |
| ABSTRACT | Techniques for ripple-type control of networked physical systems such as power systems, water systems, and others are provided. As one example, a device includes at least one processor configured to determine, for a first controllable device in a system, based on a measurement of an output parameter and a minimum output parameter value, an output violation value for the first device. The processor is further configured to determine, based on a present input value for the first device, the output violation value, and an assistance requisition value corresponding to a second device, a target input value for the first device. The processor is further configured to cause the first controllable device to modify operation based on the target input value and a maximum input value for the first controllable device. |
| FILED | Thursday, October 14, 2021 |
| APPL NO | 17/501743 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 9/02 (20130101) G05B 13/024 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984231 | Keller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NuScale Power, LLC (Portland, Oregon) |
| ASSIGNEE(S) | NuScale Power, LLC (Corvallis, Oregon) |
| INVENTOR(S) | Michael Keller (Portland, Oregon); Ross I. Snuggerud (Portland, Oregon) |
| ABSTRACT | An in-core instrumentation system for a reactor module includes a plurality of in-core instruments connected to a containment vessel and a reactor pressure vessel at least partially located within the containment vessel. A reactor core is housed within a lower head that is removably attached to the reactor pressure vessel, and lower ends of the in-core instruments are located within the reactor core. The in-core instruments are configured such that the lower ends are concurrently removed from the reactor core as a result of removing the lower head from the reactor pressure vessel. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 17/554967 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 1/08 (20130101) G21C 1/32 (20130101) G21C 13/02 (20130101) G21C 17/10 (20130101) G21C 19/02 (20130101) G21C 19/07 (20130101) G21C 19/18 (20130101) Original (OR) Class G21C 19/20 (20130101) G21C 19/32 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984243 | Parker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee); Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | David S. Parker (Oak Ridge, Tennessee); Tribhuwan Pandey (Oak Ridge, Tennessee); Cajetan Ikenna Nlebedim (Ames, Iowa); Xubo Liu (Ames, Iowa) |
| ABSTRACT | Permanent magnet materials are provided. The permanent magnet materials are cerium based materials including zirconium and iron in combination with cobalt. The permanent magnet materials may have the formula Ce2ZrFe15−xCox wherein 6≤x≤15. In some embodiments, the permanent magnet materials have the formula Ce2+yZr1−yFe(15−x)(2−z)/2)CoxCu((15−x)z/2) wherein 6≤x≤15, 0≤y≤0.4, and z=0 or 1. In other embodiments, the permanent magnet materials have the formula Ce2Zrx(Fe1−yCoy)17−2x, where 0<x≤1 and 0.4≤y≤1. Permanent magnets including the permanent magnet materials are also provided. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 17/685672 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/055 (20130101) Original (OR) Class H01F 41/0293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984259 | Tapadia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Renovables España, S.L. (Barcelona, Spain) |
| INVENTOR(S) | Nidhishri Tapadia (Arvada, Colorado); David Allan Torrey (Ballston Spa, New York) |
| ABSTRACT | An electrical generator and method for operating the same are provided. Accordingly, the generator includes a non-rotatable component supporting a field winding assembly and a rotatable component oriented to rotate relative thereto. The generator also includes an armature winding assembly fixedly coupled to the rotatable component so as to rotate therewith during operation of the generator. The generator also includes a resistive assembly fixedly coupled to the rotatable component so as to rotate therewith during the operation of the generator. The resistive assembly electrically couples at least two separate phase windings of the armature winding assembly. The resistive assembly is also configured to introduce a resistance into the armature winding assembly in response to an electrical fault. |
| FILED | Tuesday, March 16, 2021 |
| APPL NO | 18/550556 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Wind Motors F03D 9/255 (20170201) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 6/06 (20130101) Original (OR) Class Dynamo-electric Machines H02K 7/1838 (20130101) H02K 9/20 (20130101) H02K 55/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984553 | Visco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California); Vitaliy Nimon (San Francisco, California) |
| ABSTRACT | A lithium ion-conductive solid electrolyte including a freestanding inorganic vitreous sheet of sulfide-based lithium ion conducting glass is capable of high performance in a lithium metal battery. Such an electrolyte is also manufacturable, and readily adaptable for battery cell and cell component manufacture, in a cost-effective, scalable manner using an automated machine based system, apparatus and methods based on inline spectrophotometry to assess and inspect the quality of such vitreous solid electrolyte sheets and associated components. Suitable manufacturing methods can involve multi-stage thinning of a sulfide glass preform that includes a first thinning operation that involves applying a compressive force onto the preform to form a glass sheet and a second thinning operation that involves applying a tensile force on the as-formed glass sheet (e.g., drawing the sheet by pulling). |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 16/721787 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) G01N 21/896 (20130101) G01N 2021/8967 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/0407 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 10/0566 (20130101) H01M 50/46 (20210101) H01M 50/406 (20210101) H01M 50/437 (20210101) H01M 50/497 (20210101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984577 | Du et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Zhijia Du (Knoxville, Tennessee); Christopher James Janke (Oliver Springs, Tennessee); Jianlin Li (Knoxville, Tennessee); David L. Wood, III (Knoxville, Tennessee); Claus Daniel (Knoxville, Tennessee) |
| ABSTRACT | A method of making an electrode includes the step of mixing active material particles, radiation curable resin precursors, and electrically conductive particles to create an electrode precursor mixture. The electrode precursor mixture is electrostatically sprayed onto a current collector to provide an electrode preform. The electrode preform is heated and calendered to melt the resin precursor such that the resin precursor surrounds the active particles and electrically conductive particles. Radiation is applied to the electrode preform sufficient to cure the radiation curable resin precursors into resin. |
| FILED | Tuesday, March 29, 2022 |
| APPL NO | 17/707563 |
| ART UNIT | 1759 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/0404 (20130101) H01M 4/0419 (20130101) Original (OR) Class H01M 4/0435 (20130101) H01M 4/0471 (20130101) H01M 4/621 (20130101) H01M 4/1315 (20130101) H01M 4/1391 (20130101) H01M 4/1393 (20130101) H01M 4/1397 (20130101) H01M 4/13915 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984815 | Awal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | M A Awal (Raleigh, North Carolina); Srdjan Lukic (Raleigh, North Carolina); Iqbal Husain (Raleigh, North Carolina) |
| ABSTRACT | Disclosed herein is a modular, scalable, and galvanically isolated power electronics converter topology for medium voltage AC (MVAC) to DC or high voltage AC (HVAC) to DC power conversion. A disclosed modular converter can comprise a low-voltage direct current bus and a centralized controller configured to regulate the low-voltage direct current bus. The modular converter can further comprise a plurality of three-phase blocks connected in series. Individual three-phase blocks of the plurality of three-phase blocks can comprise a plurality of single-phase modules connected in an input-series output-parallel configuration. The modular converter can further comprise a filter connected between a grid input and the plurality of three-phase blocks and a pulse-width modulator configured to generate encoded gate pulses for the individual three-phase blocks of the plurality of three-phase blocks. |
| FILED | Thursday, May 26, 2022 |
| APPL NO | 17/825211 |
| ART UNIT | 2839 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/007 (20210501) H02M 1/0012 (20210501) H02M 1/12 (20130101) H02M 1/36 (20130101) H02M 1/045 (20130101) H02M 1/0067 (20210501) H02M 1/0074 (20210501) H02M 3/33573 (20210501) H02M 3/33584 (20130101) H02M 7/219 (20130101) H02M 7/797 (20130101) H02M 7/2173 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11985060 | Froese |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| INVENTOR(S) | Edwin L. Froese (Burnaby British Columbia, Canada) |
| ABSTRACT | Systems and methods are provided for managing a data communication within a multi-level network having a plurality of switches organized as groups, with each group coupled to all other groups via global links, including: at each switch within the network, maintaining a global fault table identifying the links which lead only to faulty global paths, and when the data communication is received at a port of a switch, determine a destination for the data communication and, route the communication across the network using the global fault table to avoid selecting a port within the switch that would result in the communication arriving at a point in the network where its only path forward is across a global link that is faulty; wherein the global fault table is used for both a global minimal routing methodology and a global non-minimal routing methodology. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/594711 |
| ART UNIT | 2478 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) G06F 9/546 (20130101) G06F 12/0862 (20130101) G06F 12/1036 (20130101) G06F 12/1063 (20130101) G06F 13/14 (20130101) G06F 13/16 (20130101) G06F 13/385 (20130101) G06F 13/1642 (20130101) G06F 13/1673 (20130101) G06F 13/1689 (20130101) G06F 13/4022 (20130101) G06F 13/4068 (20130101) G06F 13/4221 (20130101) G06F 15/17331 (20130101) G06F 2212/50 (20130101) G06F 2213/0026 (20130101) G06F 2213/3808 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0083 (20130101) H04L 43/10 (20130101) H04L 43/0876 (20130101) H04L 45/16 (20130101) H04L 45/20 (20130101) H04L 45/021 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/028 (20130101) H04L 45/28 (20130101) Original (OR) Class H04L 45/38 (20130101) H04L 45/42 (20130101) H04L 45/46 (20130101) H04L 45/70 (20130101) H04L 45/122 (20130101) H04L 45/123 (20130101) H04L 45/125 (20130101) H04L 45/566 (20130101) H04L 45/745 (20130101) H04L 45/7453 (20130101) H04L 47/11 (20130101) H04L 47/12 (20130101) H04L 47/18 (20130101) H04L 47/20 (20130101) H04L 47/22 (20130101) H04L 47/24 (20130101) H04L 47/30 (20130101) H04L 47/32 (20130101) H04L 47/34 (20130101) H04L 47/39 (20130101) H04L 47/52 (20130101) H04L 47/76 (20130101) H04L 47/80 (20130101) H04L 47/122 (20130101) H04L 47/323 (20130101) H04L 47/621 (20130101) H04L 47/626 (20130101) H04L 47/629 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) H04L 47/2466 (20130101) H04L 47/2483 (20130101) H04L 47/6235 (20130101) H04L 47/6275 (20130101) H04L 49/15 (20130101) H04L 49/30 (20130101) H04L 49/90 (20130101) H04L 49/101 (20130101) H04L 49/3009 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) H04L 49/9005 (20130101) H04L 49/9021 (20130101) H04L 49/9036 (20130101) H04L 49/9047 (20130101) H04L 67/1097 (20130101) H04L 69/22 (20130101) H04L 69/28 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11985113 | Edgar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Thomas W. Edgar (Richland, Washington); Thomas E. Carroll (Richland, Washington); Garret E. Seppala (Richland, Washington) |
| ABSTRACT | Computing system operational methods and apparatus are described. According to one aspect, a computing system operational method includes accessing user information regarding a user logging onto a computing device of the computing system, processing the user information to determine if the user information is authentic, as a result of the processing determining that the user information is authentic, first enabling the computing device to execute an application segment, and as a result of the processing determining that the user information is authentic, second enabling the application segment to communicate data externally of the computing device via one of a plurality of network segments of the computing system. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 17/584885 |
| ART UNIT | 2498 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) G06F 21/316 (20130101) G06F 2009/45587 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0803 (20130101) H04L 63/20 (20130101) H04L 63/102 (20130101) H04L 63/164 (20130101) H04L 63/0428 (20130101) Original (OR) Class H04L 67/561 (20220501) H04L 67/563 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11985836 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Kai Zhu (Littleton, Colorado); Qi Jiang (Golden, Colorado); Jinhui Tong (Wuhan, China PRC) |
| ABSTRACT | The present disclosure relates to a device that includes a layer that includes a perovskite, where the layer has a first side and a second side defining a thickness, the perovskite has a bulk composition as defined by AB(X1-yXy′)3, where A includes a first cation, B includes a second cation, X includes iodide, and X′ includes bromide, y is between 0.2 and 0.8, inclusively, and the thickness has a bromide concentration gradient across the thickness with a maximum concentration at or in the proximity of the first side and a minimum concentration at the second side. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/177232 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/0036 (20130101) H01G 9/2009 (20130101) Organic electric solid-state devices H10K 30/57 (20230201) Original (OR) Class H10K 71/16 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11985888 | Forrest et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Jongchan Kim (Ann Arbor, Michigan) |
| ABSTRACT | An organic light emitting device (OLED) comprises an anode; a cathode; and a light emitting layer, disposed between the anode and the cathode; wherein the light emitting layer comprises at least one luminescent compound; and wherein the transition dipole moment of the at least one luminescent compound is oriented parallel to the surface of the light emitting layer. A method of fabricating a light emitting layer, comprises the steps of providing a substrate; depositing less than 2 nm of a template material on the substrate; and depositing a composition comprising at least one light emitting compound on the template material. |
| FILED | Thursday, July 30, 2020 |
| APPL NO | 16/943906 |
| ART UNIT | 2821 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Organic electric solid-state devices H10K 30/353 (20230201) H10K 71/164 (20230201) H10K 85/346 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11980462 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Joseph Wang (San Diego, California); Patrick Mercier (San Diego, California) |
| ABSTRACT | Methods, systems, and devices are disclosed mouth-based biosensors and biofuel cells. In one aspect, an electrochemical sensor device for detecting analytes in saliva includes a substrate including an electrically insulative material, a first electrode disposed on the substrate at a first location, in which the first electrode includes a surface including a chemical agent (e.g., a catalyst or a reactant) corresponding to an analyte in saliva; and a second electrode disposed on the substrate at a second location separated from the first electrode by a spacing region, the first and second electrodes capable of sustaining a redox reaction involving the chemical agent and the analyte to produce an electrical signal, such that, when the device is present in the mouth of a user and electrically coupled to an electrical circuit, the device is operable to detect the analyte in the user's saliva. |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 16/789316 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/682 (20130101) A61B 5/1486 (20130101) Original (OR) Class A61B 5/6802 (20130101) A61B 5/7225 (20130101) A61B 5/14507 (20130101) A61B 5/14532 (20130101) A61B 5/14546 (20130101) A61B 10/0051 (20130101) A61B 2560/0214 (20130101) A61B 2560/0462 (20130101) A61B 2562/0295 (20130101) Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 19/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3272 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/16 (20130101) H01M 8/22 (20130101) H01M 8/0239 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980468 | Mendenhall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); UPMC (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); UPMC (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | George Stuart Mendenhall (Pittsburgh, Pennsylvania); Matthew Jones (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed are wearable devices, such as rings and bracelets, for monitoring and diagnosing cardiovascular conditions of a wearer, along with related systems, algorithms and methods. The disclosed wearable devices can continuously monitor the wearer's cardiovascular status by measuring heart rate, motion, blood oxygenation, and/or other properties of the wearer. Disclosed wearable devices can further comprise three EKG electrodes, including a first electrode on the inner surface adapted to detect a signal from the finger/wrist, a second electrode on the outer surface adapted to detect a cardiovascular signal from a finger of the opposing hand, and a third electrode on the outer surface of the frame adapted to detect a cardiovascular signal from a EKG lead location on the wearer's chest or leg. The wearable devices can be linked wirelessly to a mobile device that the person can interact with, and can further be linked to other distributed system components and healthcare providers. |
| FILED | Friday, October 23, 2020 |
| APPL NO | 17/078527 |
| ART UNIT | 3796 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/11 (20130101) A61B 5/0022 (20130101) A61B 5/25 (20210101) Original (OR) Class A61B 5/0205 (20130101) A61B 5/349 (20210101) A61B 5/389 (20210101) A61B 5/683 (20130101) A61B 5/02438 (20130101) A61B 5/6826 (20130101) A61B 5/7275 (20130101) A61B 5/14552 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/048 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11980936 | Niauzorau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stanislau Niauzorau (Gilbert, Arizona); Aliaksandr Sharstniou (Gilbert, Arizona); Amm G. Hasib (Tempe, Arizona); Bruno Azeredo (Tempe, Arizona); Natalya Kublik (Tempe, Arizona); Kenan Song (Gilbert, Arizona); Nikhilesh Chawla (West Lafayette, Indiana); Sridhar Niverty (West Lafayette, Indiana) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona); Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Stanislau Niauzorau (Gilbert, Arizona); Aliaksandr Sharstniou (Gilbert, Arizona); Amm G. Hasib (Tempe, Arizona); Bruno Azeredo (Tempe, Arizona); Natalya Kublik (Tempe, Arizona); Kenan Song (Gilbert, Arizona); Nikhilesh Chawla (West Lafayette, Indiana); Sridhar Niverty (West Lafayette, Indiana) |
| ABSTRACT | A method of making a metal-polymer composite includes dealloying metallic powder to yield porous metal particles, monitoring a temperature of the mixture, controlling the rate of combining, a maximum temperature of the mixture, or both, and combining the porous metal particles with a polymer to yield a composite. Dealloying includes combining the metallic powder with an etchant to yield a mixture. A metal-polymer composite includes porous metal particles having an average particle size of about 0.2 μm to about 500 μm and a thermoplastic or thermoset polymer. The polymer composite comprises at least 10 vol % of the porous metal particles. A powder mixture includes porous metal particles having an average particle size of about 0.2 μm to about 500 μm and a metal powder. The powder mixture includes about 1 wt % to about 99 wt % of the porous metal particles. |
| FILED | Wednesday, June 15, 2022 |
| APPL NO | 17/841371 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/05 (20220101) B22F 1/10 (20220101) Original (OR) Class B22F 1/145 (20220101) B22F 10/18 (20210101) B22F 2301/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/10 (20200101) B33Y 70/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981352 | Anthony et al. |
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| FUNDED BY |
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| APPLICANT(S) | Perceptive Automata, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Perceptive Automata, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Samuel English Anthony (Cambridge, Massachusetts); Kshitij Misra (Cambridge, Massachusetts); Avery Wagner Faller (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for predicting user interaction with vehicles. A computing device receives an image and a video segment of a road scene, the first at least one of an image and a video segment being taken from a perspective of a participant in the road scene and then generates stimulus data based on the image and the video segment. Stimulus data is transmitted to a user interface and response data is received, which includes at least one of an action and a likelihood of the action corresponding to another participant in the road scene. The computing device aggregates a subset of the plurality of response data to form statistical data and a model is created based on the statistical data. The model is applied to another image or video segment and a prediction of user behavior in the another image or video segment is generated. |
| FILED | Wednesday, March 03, 2021 |
| APPL NO | 17/190631 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/00 (20130101) B60W 60/00274 (20200201) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 2201/0213 (20130101) Electric Digital Data Processing G06F 18/41 (20230101) G06F 18/214 (20230101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) G06N 3/084 (20130101) G06N 5/01 (20230101) G06N 20/10 (20190101) Image or Video Recognition or Understanding G06V 10/7784 (20220101) G06V 20/41 (20220101) G06V 20/58 (20220101) G06V 40/20 (20220101) Traffic Control Systems G08G 1/04 (20130101) G08G 1/166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981557 | Bandara et al. |
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| FUNDED BY |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas); University of Rhode Island Board of Trustees (Kingston, Rhode Island) |
| ASSIGNEE(S) | SOUTHERN METHODIST UNIVERSITY (Dallas, Texas) |
| INVENTOR(S) | Y. M. Nuwan D. Y. Bandara (Canberra, Australia); Buddini I. Karawdeniya (Canberra, Australia); Jugal Saharia (Dallas, Texas); Min Jun Kim (Plano, Texas); Jason Rodger Dwyer (Providence, Rhode Island) |
| ABSTRACT | The present invention includes one or more nanopores in a SixNy membrane comprising a monoprotic surface termination, methods of making, and methods of using the one or more nanopores, where the one or more nanopores are a chemically-tuned controlled dielectric breakdown (CT-CDB) nanopore membrane, wherein the CT-CDB allows for long-term stability of measurements in the presence of only electrolyte (open pore current stability) and ability to support many molecular detection events. In addition, the CT-CBD has pore that unclog spontaneously, in response to voltage cessation or application, or both. |
| FILED | Friday, April 16, 2021 |
| APPL NO | 17/232624 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00864 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 1/002 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 40/00 (20130101) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981571 | Nel et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Andre E. Nel (Sherman Oaks, California); Tian Xia (Los Angeles, California); Ruibin Li (Los Angeles, California); Mark C. Hersam (Wilmette, Illinois); Nikhita D. Mansukhani (Allston, Massachusetts); Linda Guiney (Chicago, Illinois) |
| ABSTRACT | In various embodiments functionalized graphene oxide(s) are provided that demonstrate improved antimicrobial activity, where the graphene oxide(s) are functionalized to increase carbon radical (·C) density. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/531651 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/90 (20130101) A01N 59/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/08 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/198 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981756 | Moore, II et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| INVENTOR(S) | John P. Moore, II (Fayetteville, Arkansas); Jamie Hestekin (Fayetteville, Arkansas); Peter Crooks (Little Rock, Arkansas); Narsimha Reddy Penthala (Little Rock, Arkansas); Shobanbabu Bommagani (Little Rock, Arkansas); Soma Shekar Dachavaram (Little Rock, Arkansas) |
| ABSTRACT | In one aspect, TEMPO-cellulose structures and method of making the same are described herein. Briefly, a method of synthesizing TEMPO-cellulose comprises disposing cellulose in an aqueous medium, disposing first and second oxidizing agents in the aqueous medium and oxidizing hydroxyl groups of the cellulose via the first and second oxidizing agents in the presence of a 2,2,6,6-tetramethylpiperidine 1-oxyl radical (TEMPO) catalyst. |
| FILED | Monday, July 30, 2018 |
| APPL NO | 16/634703 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 65/466 (20130101) B65D 81/18 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Polysaccharides; Derivatives Thereof C08B 15/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981777 | Pugh et al. |
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| FUNDED BY |
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| APPLICANT(S) | Coleen Pugh (Akron, Ohio); Chenwei Liu (Patchogue, New York); Cesar Lopez Gonzalez (Akron, Ohio); Chenying Zhao (Houston, Texas) |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Coleen Pugh (Akron, Ohio); Chenwei Liu (Patchogue, New York); Cesar Lopez Gonzalez (Akron, Ohio); Chenying Zhao (Houston, Texas) |
| ABSTRACT | A new synthetic pathway for hyperbranched polyacrylates and polymethacrylates including the steps of preparing an inimer and polymerizing the inimer to form hyperbranched polymers or copolymers. |
| FILED | Tuesday, August 20, 2019 |
| APPL NO | 16/545470 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/24 (20130101) A61L 15/64 (20130101) A61L 26/009 (20130101) A61L 26/0014 (20130101) Peptides C07K 1/145 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 20/68 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/005 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 135/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981789 | Han et al. |
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| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico); Sang Eon Han (Albuquerque, New Mexico); Sang M. Han (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| INVENTOR(S) | Sang Eon Han (Albuquerque, New Mexico); Sang M. Han (Albuquerque, New Mexico) |
| ABSTRACT | A method and resulting device that mimics the light scattering properties of a random structural pattern using microspheres. |
| FILED | Monday, September 17, 2018 |
| APPL NO | 16/647404 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/26 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/278 (20130101) G01N 23/2202 (20130101) G01N 23/2251 (20130101) Optical Elements, Systems, or Apparatus G02B 5/0268 (20130101) G02B 2207/109 (20130101) Image Data Processing or Generation, in General G06T 7/50 (20170101) Electric Discharge Tubes or Discharge Lamps H01J 37/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981805 | Bailey et al. |
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| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| INVENTOR(S) | Travis S. Bailey (Fort Collins, Colorado); Allee S. Klug (Loveland, Colorado) |
| ABSTRACT | The present disclosure relates to triblock and pentablock copolymers and methods of making thereof. Aspects of the disclosure further relate to block copolymer hydrogels that exhibit both fatigue resistance and fracture resistance with superior rates of recovery. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 17/445910 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0065 (20130101) Compositions of Macromolecular Compounds C08L 25/06 (20130101) C08L 47/00 (20130101) C08L 53/02 (20130101) Original (OR) Class C08L 71/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11981956 | Saka et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Sinem K. Saka (Cambridge, Massachusetts); Jocelyn Yoshiko Kishi (Cambridge, Massachusetts); Peng Yin (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein, in some embodiments, are compositions and methods for proximity detection of molecular targets. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/964527 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/682 (20130101) Original (OR) Class C12Q 1/6804 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982637 | Yao et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Jun Yao (Boston, Massachusetts); Derek R. Lovley (Amherst, Massachusetts); Alexander Smith (Boston, Massachusetts); Xiaomeng Liu (Boston, Massachusetts) |
| ABSTRACT | A gas sensor includes a biomaterial comprising electrically-conductive protein nanowires and at least two electrodes. The at least two electrodes are in operative arrangement with the protein nanowires and configured to provide a signal indicative of a change in conductivity of the protein nanowires. The conductivity of the protein nanowires is responsive to a change in concentration of a gas exposed to the biomaterial, such as ammonia, or to a change in relative humidity. |
| FILED | Thursday, April 22, 2021 |
| APPL NO | 17/302063 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/082 (20130101) A61B 2562/0285 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/121 (20130101) G01N 27/127 (20130101) Original (OR) Class G01N 33/0054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11982693 | Parkhideh et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of North Carolina Charlotte (Charlotte, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Charlotte (Charlotte, North Carolina) |
| INVENTOR(S) | Babak Parkhideh (Charlotte, North Carolina); Andreas Lauer (Charlotte, North Carolina) |
| ABSTRACT | Apparatuses and methods of the present disclosure integrate a non-intrusive current sensor in the form of a current mismatch sensor into a power module having paralleled semiconductor structures or components. The current mismatch can be detected by the current sensor by monitoring a magnetic flux density between the paralleled components or devices. |
| FILED | Thursday, October 10, 2019 |
| APPL NO | 16/598457 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 15/205 (20130101) Original (OR) Class Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/181 (20130101) H05K 2201/10151 (20130101) H05K 2201/10166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11983079 | Gopalan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| INVENTOR(S) | Kartik Gopalan (Vestal, New York); Ping Yang (Vestal, New York); Dinuni K. Fernando (Hapugoda, Sri Lanka); Jonathan Terner (Beacon, New York) |
| ABSTRACT | Post-copy is one of the two key techniques (besides pre-copy) for live migration of virtual machines in data centers. Post-copy provides deterministic total migration time and low downtime for write-intensive VMs. However, if post-copy migration fails for any reason, the migrating VM is lost because the VM's latest consistent state is split between the source and destination nodes during migration. PostCopyFT provides a new approach to recover a VM after a destination or network failure during post-copy live migration using an efficient reverse incremental checkpointing mechanism. PostCopyFT was implemented and evaluated in the KVM/QEMU platform. Experimental results show that the total migration time of post-copy remains unchanged while maintaining low failover time, downtime, and application performance overhead. |
| FILED | Monday, August 08, 2022 |
| APPL NO | 17/818234 |
| ART UNIT | RD00 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) G06F 11/301 (20130101) G06F 11/0772 (20130101) G06F 11/0793 (20130101) G06F 11/1451 (20130101) G06F 11/1471 (20130101) G06F 11/1484 (20130101) Original (OR) Class G06F 2009/4557 (20130101) G06F 2009/45583 (20130101) G06F 2201/84 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11983630 | Iandola et al. |
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| FUNDED BY |
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| APPLICANT(S) | Tesla, Inc. (Austin, Texas) |
| ASSIGNEE(S) | Tesla, Inc. (Austin, Texas) |
| INVENTOR(S) | Forrest Nelson Iandola (San Jose, California); Harsimran Singh Sidhu (Fremont, California); Yiqi Hou (Berkeley, California) |
| ABSTRACT | A neural network architecture is used that reduces the processing load of implementing the neural network. This network architecture may thus be used for reduced-bit processing devices. The architecture may limit the number of bits used for processing and reduce processing to prevent data overflow at individual calculations of the neural network. To implement this architecture, the number of bits used to represent inputs at levels of the network and the related filter masks may also be modified to ensure the number of bits of the output does not overflow the resulting capacity of the reduced-bit processor. To additionally reduce the load for such a network, the network may implement a “starconv” structure that permits the incorporation of nearby nodes in a layer to balance processing requirements and permit the network to learn from context of other nodes. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/156628 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/575 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11983825 | Nandi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Arnab Nandi (Columbus, Ohio); Codi Burley (Grove City, Ohio); Ritesh Sarkhel (Columbus, Ohio) |
| ABSTRACT | Systems and methods are provided that allow developers to quickly and easily develop augmented reality (AR) applications that enrich the real-world with data from the cloud. Given that the development of an AR application is a complex and time-consuming process, the systems and methods described herein allow software developers to concisely describe their needs in a succinct program, written in the QWL domain-specific language. The systems and methods take this program and automatically generate an AR application. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/208196 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 8/433 (20130101) G06F 16/2468 (20190101) G06F 16/24544 (20190101) Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984861 | Odame et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Kofi Odame (Hanover, New Hampshire); Yueh-Ching Teng (Lebanon, New Hampshire) |
| ABSTRACT | An amplitude detector has a phase shifter such as one using an analog differentiator and an adjustable gain stage, or one using a determinable delay, the phase shifter coupled to shift phase of an input signal to the amplitude detection apparatus. The detector also has a first analog multiplier coupled to square the input signal, a second analog multiplier coupled to square output of the phase shifter; and an analog adder coupled to sum outputs of the first and second analog multiplier. An automatic gain control circuit has the amplitude detector coupled to control gain of a controllable amplifier. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/116755 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Amplifiers H03F 3/24 (20130101) Control of Amplification H03G 3/3036 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11985451 | Kim et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Donggyu Kim (Cambridge, Massachusetts); Alexander Keesling Contreras (Boston, Massachusetts); Ahmed Omran (Somerville, Massachusetts); Harry Jay Levine (Cambridge, Massachusetts); Hannes Bernien (Somerville, Massachusetts); Mikhail D. Lukin (Cambridge, Massachusetts); Dirk R. Englund (Cambridge, Massachusetts) |
| ABSTRACT | A method of generating uniform large-scale optical focus arrays (LOT As) with a phase spatial light modulator (SLM) includes identifying and removing undesired phase rotation in the iterative Fourier transform algorithm (IFTA), thereby producing computer-generated holograms of highly uniform LOT As using a reduced number of iterations as compared to a weighted Gerchberg-Saxton algorithm. The method also enables a faster compensation of optical system-induced LOT A intensity inhomogeneity than the conventional IFTA. |
| FILED | Friday, February 21, 2020 |
| APPL NO | 17/432723 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Holographic Processes or Apparatus G03H 1/0808 (20130101) G03H 2001/0816 (20130101) Pictorial Communication, e.g Television H04N 9/317 (20130101) H04N 9/3102 (20130101) H04N 9/3138 (20130101) Original (OR) Class H04N 9/3197 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11985802 | Alissa et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of new York (Binghamton, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Binghamton, New York) |
| INVENTOR(S) | Husam Alissa (Redmond, Washington); Kourosh Nemati (Rockville, Maryland); Baghat Sammakia (Binghamton, New York); Kanad Ghose (Vestal, New York) |
| ABSTRACT | A method of controlling a data center having a cold air cooling system, and at least one containment structure, comprising: determining a minimum performance constraint; determining optimum states of the cold air cooling system, a controlled leakage of air across the containment structure between a hot region and a cold air region, and information technology equipment for performing tasks to meet the minimum performance constraint, to minimize operating cost; and generating control signals to the cold air cooling system, a controlled leakage device, and the information technology equipment in accordance with the determined optimum states. |
| FILED | Saturday, July 24, 2021 |
| APPL NO | 17/384733 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/041 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20745 (20130101) H05K 7/20836 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11985910 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Samsung Electronics Co., Ltd. (Suwon-si, South Korea); President and Fellows Of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Samsung Electronics Co., Ltd. (Gyeonggi-do, South Korea) |
| INVENTOR(S) | Minhyun Lee (Suwon-si, South Korea); Dovran Amanov (Cambridge, Massachusetts); Renjing Xu (Cambridge, Massachusetts); Houk Jang (Cambridge, Massachusetts); Haeryong Kim (Seongnam-si, South Korea); Hyeonjin Shin (Suwon-si, South Korea); Yeonchoo Cho (Seongnam-si, South Korea); Donhee Ham (Cambridge, Massachusetts) |
| ABSTRACT | Provided are memristors and neuromorphic devices including the memristors. A memristor includes a lower electrode and an upper electrode that are apart from each other and first and second two-dimensional material layers that are arranged between the lower electrode and the upper electrode and stacked without a chemical bond therebetween. |
| FILED | Thursday, June 09, 2022 |
| APPL NO | 17/836435 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Electronic Memory Devices H10B 63/80 (20230201) Electric solid-state devices not otherwise provided for H10N 70/24 (20230201) H10N 70/826 (20230201) Original (OR) Class H10N 70/8416 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11983467 | Murphy et al. |
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| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (, None) |
| INVENTOR(S) | Patrick C. Murphy (Suffolk, Virginia); Pieter G. Buning (Yorktown, Virginia); Benjamin M. Simmons (Yorktown, Virginia) |
| ABSTRACT | A Rapid Aero Modeling program and process may be applied to computational experiments such as computational fluid dynamics (CFD) programs to obtain aerodynamic models which may be in the form of polynomial equations. The program and process may be utilized to estimate (develop) aerodynamic models appropriate for flight dynamics studies, simulations, and the like. Feedback loops are provided around computational codes to rapidly guide testing toward aerodynamic models that meet user-defined fidelity criteria. A user has the freedom to choose a specific level of fidelity in terms of prediction error, in advance of a CFD test (computation). |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144995 |
| ART UNIT | 2148 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electric Digital Data Processing G06F 30/15 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984584 | Yushin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sila Nanotechnologies Inc. (Alameda, California) |
| ASSIGNEE(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); SILA NANOTECHNOLOGIES, INC. (Alameda, California) |
| INVENTOR(S) | Gleb Yushin (Atlanta, Georgia); Oleksandr Magazynskyy (Atlanta, Georgia); Patrick Dixon (Dunwoody, Georgia); Benjamin Hertzberg (New York, New York) |
| ABSTRACT | Described herein are improved composite anodes and lithium-ion batteries made therefrom. Further described are methods of making and using the improved anodes and batteries. In general, the anodes include a porous composite having a plurality of agglomerated nanocomposites. At least one of the plurality of agglomerated nanocomposites is formed from a dendritic particle, which is a three-dimensional, randomly-ordered assembly of nanoparticles of an electrically conducting material and a plurality of discrete non-porous nanoparticles of a non-carbon Group 4A element or mixture thereof disposed on a surface of the dendritic particle. At least one nanocomposite of the plurality of agglomerated nanocomposites has at least a portion of its dendritic particle in electrical communication with at least a portion of a dendritic particle of an adjacent nanocomposite in the plurality of agglomerated nanocomposites. |
| FILED | Friday, September 24, 2021 |
| APPL NO | 17/484451 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/18 (20130101) H01B 1/24 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/137 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/587 (20130101) H01M 4/602 (20130101) H01M 4/625 (20130101) H01M 4/1393 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/70 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11983630 | Iandola et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tesla, Inc. (Austin, Texas) |
| ASSIGNEE(S) | Tesla, Inc. (Austin, Texas) |
| INVENTOR(S) | Forrest Nelson Iandola (San Jose, California); Harsimran Singh Sidhu (Fremont, California); Yiqi Hou (Berkeley, California) |
| ABSTRACT | A neural network architecture is used that reduces the processing load of implementing the neural network. This network architecture may thus be used for reduced-bit processing devices. The architecture may limit the number of bits used for processing and reduce processing to prevent data overflow at individual calculations of the neural network. To implement this architecture, the number of bits used to represent inputs at levels of the network and the related filter masks may also be modified to ensure the number of bits of the output does not overflow the resulting capacity of the reduced-bit processor. To additionally reduce the load for such a network, the network may implement a “starconv” structure that permits the incorporation of nearby nodes in a layer to balance processing requirements and permit the network to learn from context of other nodes. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/156628 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/575 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11984584 | Yushin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sila Nanotechnologies Inc. (Alameda, California) |
| ASSIGNEE(S) | GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); SILA NANOTECHNOLOGIES, INC. (Alameda, California) |
| INVENTOR(S) | Gleb Yushin (Atlanta, Georgia); Oleksandr Magazynskyy (Atlanta, Georgia); Patrick Dixon (Dunwoody, Georgia); Benjamin Hertzberg (New York, New York) |
| ABSTRACT | Described herein are improved composite anodes and lithium-ion batteries made therefrom. Further described are methods of making and using the improved anodes and batteries. In general, the anodes include a porous composite having a plurality of agglomerated nanocomposites. At least one of the plurality of agglomerated nanocomposites is formed from a dendritic particle, which is a three-dimensional, randomly-ordered assembly of nanoparticles of an electrically conducting material and a plurality of discrete non-porous nanoparticles of a non-carbon Group 4A element or mixture thereof disposed on a surface of the dendritic particle. At least one nanocomposite of the plurality of agglomerated nanocomposites has at least a portion of its dendritic particle in electrical communication with at least a portion of a dendritic particle of an adjacent nanocomposite in the plurality of agglomerated nanocomposites. |
| FILED | Friday, September 24, 2021 |
| APPL NO | 17/484451 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/18 (20130101) H01B 1/24 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/137 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/587 (20130101) H01M 4/602 (20130101) H01M 4/625 (20130101) H01M 4/1393 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/70 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11983656 | Torres Soto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Adyani Torres Soto (Washington, District of Columbia); Robert Charles Moran (Crofton, Maryland); Jodi Lee Webb (Batavia, Illinois); John Patrick Byrne (Bethesda, Maryland); Edward H. Ryan (Millersville, Maryland); Ilse H. Fogl (Raleigh, North Carolina) |
| ABSTRACT | Systems and methods for informed mobility platform for an item processing supervisor within a distribution facility are disclosed. In one embodiment, a supervisor mobile terminal for electronically managing item processing activities associated with a distribution facility is provided. The terminal may include a transceiver circuit configured to wirelessly communicate with a server computer a plurality of sets of data relating to the item processing activities. The terminal may further include a user interface configured to display the plurality of sets of data and a controller in data communication with the transceiver circuit and the user interface. The controller may be configured to control the user interface to modify the at least one set of data and control the transceiver circuit to wirelessly communicate the modified data with the server computer such that the at least one set of data stored in the server computer is updated with the modified data. |
| FILED | Friday, May 01, 2020 |
| APPL NO | 16/865206 |
| ART UNIT | 3624 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 23/0216 (20130101) Electric Digital Data Processing G06F 3/0484 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/08 (20130101) Original (OR) Class G06Q 10/0635 (20130101) G06Q 10/0639 (20130101) G06Q 10/0833 (20130101) G06Q 10/0835 (20130101) G06Q 10/1091 (20130101) G06Q 10/06312 (20130101) G06Q 10/06315 (20130101) G06Q 30/0281 (20130101) G06Q 50/26 (20130101) G06Q 50/60 (20240101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11983662 | Tartal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | William Albert Tartal (Baltimore, Maryland); Gabriel Michael Yessin (Arlington, Virginia); Dominique Danielle Strothers (Front Royal, Virginia); Joram Shenhar (Fairfax, Virginia); Joel Locknauth Dewnandan (Bladensburg, Maryland); Terry Martin Gingell (Spotsylvania, Virginia); James Edmund Matthews (Bowie, Maryland) |
| ABSTRACT | A process for verifying an item deposit via a smart drop box. The process includes an item receptacle, a processor in communication with the item receptacle, a scanning device, and a database. The item receptacle is configured to receive an item from a user, scan the item, and generate item information. The processor is configured to compare the item information generated with identified item information from the database. If the information generated matches the information from the database, the item is accepted. In some embodiments, the deposit verification includes a printed receipt and/or an electronic verification. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/472372 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0832 (20130101) Original (OR) Class G06Q 10/0833 (20130101) G06Q 20/202 (20130101) G06Q 20/203 (20130101) G06Q 20/204 (20130101) G06Q 20/209 (20130101) G06Q 50/32 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 9/00896 (20130101) Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing G07D 11/009 (20130101) G07D 11/14 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11981750 | Bannantine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INSTITUT PASTEUR (Paris, France); INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE L'ALIMENTATION ET L'ENVIRONNEMENT (Paris, France); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
| ASSIGNEE(S) | INSTITUT PASTEUR (Paris, France); INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE L'ALIMENTATION ET L'ENVIRONNEMENT (Paris, France); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
| INVENTOR(S) | John P. Bannantine (Ames, Iowa); Gilles Etienne (Toulouse, France); Sylvie Bay (Paris, France); Franck Biet (Notre Dame D'Oe, France) |
| ABSTRACT | The present invention is directed to an isolated synthetic tripeptide of formula H-D-Phe-N-Methyl-L-Val-L-Ala-OMe (SEQ ID NO:1), or a derivative thereof, and to the corresponding lipotripeptides, which are specific to Mycobacterium avium subsp. paratuberculosis (Map) S-type strain, as well as derivatives and conjugates thereof. The invention also concerns the use of these antigens in different methods and tests for detecting Map infection, especially by detecting humoral response and cell mediated response of infected animals. The invention is also directed to a genetic signature of Map and a mass spectrometry and NMR spectroscopy signature of Map presence or infection. |
| FILED | Friday, October 07, 2022 |
| APPL NO | 17/938865 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) A61K 47/60 (20170801) A61K 47/542 (20170801) Peptides C07K 5/0812 (20130101) Original (OR) Class C07K 7/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5695 (20130101) G01N 2333/57 (20130101) G01N 2333/5428 (20130101) G01N 2469/20 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11980238 | Harris et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LION GROUP, INC. (Dayton, Ohio); NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| ASSIGNEE(S) | LION GROUP, INC. (Dayton, Ohio); NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina) |
| INVENTOR(S) | Richard H. Harris (Beavercreek, Ohio); Alysha Lynn Gray (Beavercreek, Ohio); Kathryn Ann York (Tipp City, Ohio); Cassandra H. Kwon (Raleigh, North Carolina); Marc Christopher Mathews (Raleigh, North Carolina); Chandler Ross Maness (Portland, Oregon); Robert Bryan Ormond (Holly Springs, North Carolina) |
| ABSTRACT | A protective garment system including a bib configured to fit around at least part of an upper portion of a torso of a wearer. The bib includes an outer material and a particulate-blocking material which is configured to be positioned between the outer material and a wearer when the bib is worn. The bib has a perimeter and is configured to be releasably attached to a pair of trousers about the perimeter. |
| FILED | Wednesday, April 07, 2021 |
| APPL NO | 17/224476 |
| ART UNIT | 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/02 (20130101) Original (OR) Class A41D 13/0005 (20130101) A41D 15/00 (20130101) A41D 27/12 (20130101) A41D 27/24 (20130101) A41D 31/10 (20190201) A41D 31/085 (20190201) A41D 2300/30 (20130101) A41D 2300/32 (20130101) A41D 2300/322 (20130101) A41D 2500/20 (20130101) A41D 2600/20 (20130101) Buttons, Pins, Buckles, Slide Fasteners, or the Like A44B 19/32 (20130101) Devices, Apparatus or Methods for Life-saving A62B 17/001 (20130101) A62B 17/003 (20130101) A62B 17/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11980698 | Lancaster et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Jordan J. Lancaster (Tucson, Arizona); Steven Goldman (Tucson, Arizona) |
| ABSTRACT | Disclosed herein are contractile cell constructs, methods for using them to treat disease, and methods for making them. |
| FILED | Tuesday, June 01, 2021 |
| APPL NO | 17/335687 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) A61K 38/18 (20130101) A61K 38/18 (20130101) A61K 38/2292 (20130101) A61K 38/2292 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/367 (20130101) A61L 27/3826 (20130101) Original (OR) Class A61L 27/3873 (20130101) A61L 2300/64 (20130101) A61L 2300/412 (20130101) A61L 2430/20 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0657 (20130101) C12N 2506/1315 (20130101) C12N 2513/00 (20130101) C12N 2527/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11985060 | Froese |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| INVENTOR(S) | Edwin L. Froese (Burnaby British Columbia, Canada) |
| ABSTRACT | Systems and methods are provided for managing a data communication within a multi-level network having a plurality of switches organized as groups, with each group coupled to all other groups via global links, including: at each switch within the network, maintaining a global fault table identifying the links which lead only to faulty global paths, and when the data communication is received at a port of a switch, determine a destination for the data communication and, route the communication across the network using the global fault table to avoid selecting a port within the switch that would result in the communication arriving at a point in the network where its only path forward is across a global link that is faulty; wherein the global fault table is used for both a global minimal routing methodology and a global non-minimal routing methodology. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/594711 |
| ART UNIT | 2478 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) G06F 9/546 (20130101) G06F 12/0862 (20130101) G06F 12/1036 (20130101) G06F 12/1063 (20130101) G06F 13/14 (20130101) G06F 13/16 (20130101) G06F 13/385 (20130101) G06F 13/1642 (20130101) G06F 13/1673 (20130101) G06F 13/1689 (20130101) G06F 13/4022 (20130101) G06F 13/4068 (20130101) G06F 13/4221 (20130101) G06F 15/17331 (20130101) G06F 2212/50 (20130101) G06F 2213/0026 (20130101) G06F 2213/3808 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0083 (20130101) H04L 43/10 (20130101) H04L 43/0876 (20130101) H04L 45/16 (20130101) H04L 45/20 (20130101) H04L 45/021 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/028 (20130101) H04L 45/28 (20130101) Original (OR) Class H04L 45/38 (20130101) H04L 45/42 (20130101) H04L 45/46 (20130101) H04L 45/70 (20130101) H04L 45/122 (20130101) H04L 45/123 (20130101) H04L 45/125 (20130101) H04L 45/566 (20130101) H04L 45/745 (20130101) H04L 45/7453 (20130101) H04L 47/11 (20130101) H04L 47/12 (20130101) H04L 47/18 (20130101) H04L 47/20 (20130101) H04L 47/22 (20130101) H04L 47/24 (20130101) H04L 47/30 (20130101) H04L 47/32 (20130101) H04L 47/34 (20130101) H04L 47/39 (20130101) H04L 47/52 (20130101) H04L 47/76 (20130101) H04L 47/80 (20130101) H04L 47/122 (20130101) H04L 47/323 (20130101) H04L 47/621 (20130101) H04L 47/626 (20130101) H04L 47/629 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) H04L 47/2466 (20130101) H04L 47/2483 (20130101) H04L 47/6235 (20130101) H04L 47/6275 (20130101) H04L 49/15 (20130101) H04L 49/30 (20130101) H04L 49/90 (20130101) H04L 49/101 (20130101) H04L 49/3009 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) H04L 49/9005 (20130101) H04L 49/9021 (20130101) H04L 49/9036 (20130101) H04L 49/9047 (20130101) H04L 67/1097 (20130101) H04L 69/22 (20130101) H04L 69/28 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11984146 | Baek |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (Seoul, South Korea) |
| ASSIGNEE(S) | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (Seoul, South Korea) |
| INVENTOR(S) | Seung Heon Baek (Seoul, South Korea) |
| ABSTRACT | A neuromorphic device including: a plurality of unit weighting elements connected to a bit line in a manner that shares the bit line, each of the plurality of unit weighting elements being connected to a source line and comprising a fixed layer of which a magnetization direction is fixed, a free layer of which a magnetization direction changes in parallel with or in anti-parallel with the fixed layer, and a tunnel barrier layer arranged between the fixed layer and the free layer and a plurality of drive transistors being selectively turned on according to a plurality of bit selection signals, respectively, and correspondingly driving the unit weighting elements, respectively, wherein the plurality of unit weighting elements have different resistances in such a manner as to correspond to bits, respectively, of a synapse weight. |
| FILED | Friday, April 15, 2022 |
| APPL NO | 17/721747 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/54 (20130101) G11C 11/1655 (20130101) G11C 11/1657 (20130101) G11C 11/1673 (20130101) Original (OR) Class G11C 11/1675 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 14, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240514.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page