FedInvent™ Patents

Patent Details for Tuesday, June 04, 2024 

This page was updated on Saturday, June 08, 2024 at 03:51 PM GMT

Department of Health and Human Services (HHS) 

US 11998001 Daniele et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Stefano Daniele (New Haven, Connecticut);  Nenad Sestan (Madison, Connecticut);  John Silbereis (Hamden, Connecticut);  Zvonimir Vrselja (New Haven, Connecticut)
ABSTRACT The invention provides a system for normothermic, ex vivo restoration and preservation of an intact mammalian brain, and other organs. In certain aspects, the system is capable of preserving a brain as well as other organs, maintaining cellular integrity and cellular function for hours post mortem or after global ischemia. The invention also provides synthetic brain perfusate formulations, including a novel brain perfusion medium (BPM), which are able to reduce reperfusion injury, stimulate recovery from hypoxia, prevent edema and metabolically support the energy needs of brain function.
FILED Friday, February 08, 2019
APPL NO 16/967925
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/021 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998299 Liu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) New Jersey Institute of Technology (Newark, New Jersey)
ASSIGNEE(S) New Jersey Institute of Technology (Newark, New Jersey)
INVENTOR(S) Xuan Liu (Berkeley Heights, New Jersey);  Yahui Wang (Harrison, New Jersey)
ABSTRACT An optically computed optical coherence tomography (OC-OCT) technology is disclosed. The OC-OCT system performs depth resolved imaging by computing the Fourier transform of the interferometric spectra optically. The OC-OCT system modulates the interferometric spectra with Fourier basis function projected to a spatial light modulator and detects the modulated signal without spectral discrimination. The optical computation strategy enables volumetric OCT imaging without performing mechanical scanning and without the need for Fourier transform in a computer. OC-OCT performs Fourier transform signal processing optically, without the need of mechanical scanning, and before data acquisition unlike traditional OCT methods and systems. The scan-less OCT imaging is achieved through the use of spatial light modulator (SLM) that precisely manipulates light wave to generate output with desired amplitude and phase.
FILED Thursday, February 25, 2021
APPL NO 17/185182
ART UNIT 3798 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0066 (20130101) Original (OR) Class
A61B 5/0261 (20130101)
A61B 5/7257 (20130101)
A61B 2562/0233 (20130101)
A61B 2576/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998318 Gurcan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Metin Gurcan (Winston-Salem, North Carolina);  Aaron Moberly (Columbus, Ohio)
ABSTRACT Disclosed herein are systems and methods to detect a wide range of eardrum conditions by using visually-descriptive words of a tympanic membrane of a subject.
FILED Wednesday, December 08, 2021
APPL NO 17/545681
ART UNIT 2691 — Selective Visual Display Systems
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/126 (20130101) Original (OR) Class
A61B 5/7264 (20130101)

Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding
G10L 15/08 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998331 Shaked et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Abraham Shaked (Wynnewood, Pennsylvania);  Bao-Li Chang (Paoli, Pennsylvania);  Brendan Keating (Philadelphia, Pennsylvania);  Toumy Guettouche (Miami, Florida)
ABSTRACT The present invention relates to the discovery that the expression levels of some microRNAs (miRNAs) can use a diagnostic signature to predict transplant outcomes in a transplant recipient. Thus, in various embodiments described herein, the methods of the invention relate to methods of diagnosing a transplant subject for acute rejection such as acute cellular rejection (ACR), methods of predicting a subject's risk of having or developing ACR and methods of assessing in a subject the likelihood of a successful or failure minimization of immunosuppression therapy (IST) dosage from standard ranges.
FILED Tuesday, March 26, 2019
APPL NO 16/365194
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/15 (20130101) Original (OR) Class
A61B 10/007 (20130101)
A61B 10/0038 (20130101)
A61B 2010/0061 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/158 (20130101)
C12Q 2600/178 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 25/00 (20190201)
G16B 25/10 (20190201)
G16B 25/20 (20190201)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/50 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998438 Sicotte et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ZENFLOW, INC. (San Francisco, California)
ASSIGNEE(S) ZENFLOW, INC. (San Francisco, California)
INVENTOR(S) Marcel Song Sicotte (San Francisco, California);  Austin Michael Bly (San Clemente, California);  Ben Collett-Nye (Kumeu, New Zealand);  Shreya Mehta (San Francisco, California)
ABSTRACT Systems, devices, and methods are provided for the delivery of an implant into the prostatic urethra. Embodiments of delivery systems can include a delivery device for insertion into the patient and a proximal control device for use in controlling release of the implant from the delivery device.
FILED Tuesday, July 20, 2021
APPL NO 17/380377
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/3468 (20130101)
A61B 2017/00274 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/042 (20130101) Original (OR) Class
A61F 2/885 (20130101)
A61F 2/966 (20130101)
A61F 2002/047 (20130101)
A61F 2250/001 (20130101)

Gearing
F16H 1/06 (20130101)
F16H 1/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998439 Allen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Robert Andrew Allen (Pittsburgh, Pennsylvania);  Chelsea Elizabeth Stowell (Pittsburgh, Pennsylvania);  Yadong Wang (Allison Park, Pennsylvania)
ABSTRACT A method of fabricating a vascular graft that includes preparing a biodegradable polyester electrospun tubular core; applying an adhesive composition comprising poly(lactide) copolymer to an outer surface of the biodegradable polyester electrospun tubular core; and surrounding the adhesive-applied biodegradable polyester electrospun tubular core with a polyester sheath.
FILED Tuesday, February 18, 2020
APPL NO 16/793355
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/06 (20130101)
A61F 2/07 (20130101) Original (OR) Class

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/14 (20130101)
A61L 27/18 (20130101)
A61L 27/18 (20130101)
A61L 27/24 (20130101)
A61L 27/54 (20130101)
A61L 27/58 (20130101)
A61L 27/222 (20130101)
A61L 27/225 (20130101)
A61L 27/507 (20130101)

Compositions of Macromolecular Compounds
C08L 67/04 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/0007 (20130101)
D01D 5/0076 (20130101)
D01D 5/0084 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 11/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998443 Birge et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) LambdaVision Incorporated (Farmington, Connecticut)
ASSIGNEE(S) LambdaVision Incorporated (Farmington, Connecticut)
INVENTOR(S) Robert R Birge (Peyton, Colorado);  Nicole Wagner (Ashford, Connecticut);  Jordan A Greco (Rocky Hill, Connecticut)
ABSTRACT Protein-based subretinal implants offer a new approach to restoring vision for patients blinded by conditions such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP). The present invention relates to bacteriorhodopsin-based (BR-based) retinal implants that can be implanted in a subretinal position to replace degenerated photoreceptor cells.
FILED Tuesday, May 08, 2018
APPL NO 16/611095
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/14 (20130101) Original (OR) Class
A61F 9/0017 (20130101)
A61F 2009/00863 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/164 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/227 (20130101)
A61L 2300/252 (20130101)
A61L 2430/16 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/36046 (20130101)
A61N 5/0603 (20130101)
A61N 5/0622 (20130101)
A61N 2005/0648 (20130101)
A61N 2005/0663 (20130101)

Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/0073 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 7/023 (20190101)
B32B 2535/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998521 Sanders et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Io Therapeutics, Inc. (Spring, Texas);  Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Io Therapeutics, Inc. (Spring, Texas);  Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Martin E. Sanders (Spring, Texas);  Powel H. Brown (Houston, Texas);  Cassandra Moyer (Houston, Texas);  Abhijit Mazumdar (Houston, Texas)
ABSTRACT The present specification provides combinations of active agents for the improved treatment of Her2+ cancers and associated methods of treatments. The combinations comprise an RXR agonist and a Her2-targeted therapeutic agent and may optionally further comprise thyroid hormone.
FILED Wednesday, December 07, 2022
APPL NO 18/076997
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/216 (20130101) Original (OR) Class
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998540 Liau et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Brian B. Liau (Boston, Massachusetts);  Anoop P. Patel (Boston, Massachusetts);  Cem Sievers (Boston, Massachusetts);  Bradley E. Bernstein (Boston, Massachusetts)
ABSTRACT The present invention provides compositions and methods for the treatment of drug-tolerant glioblastoma, and in particular glioblastoma stem cells. Specifically, the methods comprise contacting a glioblastoma stem cell with a platelet-derived growth factor receptor alpha inhibitor and one or more of a histone lysine demethylase inhibitor and a Notch inhibitor.
FILED Thursday, March 24, 2016
APPL NO 16/060852
ART UNIT 1628 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/44 (20130101)
A61K 31/44 (20130101)
A61K 31/55 (20130101)
A61K 31/55 (20130101)
A61K 31/506 (20130101)
A61K 31/506 (20130101)
A61K 31/4709 (20130101) Original (OR) Class
A61K 31/4709 (20130101)
A61K 31/5513 (20130101)
A61K 31/5513 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998586 Urish et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Kenneth Urish (Sewickley, Pennsylvania);  Jonathan Brendan Mandell (Pittsburgh, Pennsylvania)
ABSTRACT A method of treating or preventing a microbial infection in a patient is provided, along with a wound irrigation system and a composition in the form of an irrigation liquid for reducing microbial load or preventing microbial infection in a wound.
FILED Friday, November 12, 2021
APPL NO 17/525344
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/546 (20130101)
A61K 38/10 (20130101) Original (OR) Class
A61K 38/1729 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998593 Ali et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Omar Abdel-Rahman Ali (Oakland, California);  David J. Mooney (Sudbury, Massachusetts);  Glenn Dranoff (Sudbury, Massachusetts)
ABSTRACT The present invention comprises compositions, methods, and devices for enhancing an endogenous immune response against a cancer. Devices and methods provide therapeutic immunity to subjects against cancer.
FILED Monday, May 18, 2020
APPL NO 16/877274
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/02 (20130101)
A61K 39/0011 (20130101) Original (OR) Class
A61K 39/12 (20130101)
A61K 39/39 (20130101)
A61K 39/00117 (20180801)
A61K 39/00118 (20180801)
A61K 39/001102 (20180801)
A61K 39/001156 (20180801)
A61K 39/001157 (20180801)
A61K 39/001171 (20180801)
A61K 39/001182 (20180801)
A61K 39/001186 (20180801)
A61K 39/001191 (20180801)
A61K 39/001192 (20180801)
A61K 39/3955 (20130101)
A61K 47/34 (20130101)
A61K 47/36 (20130101)
A61K 2039/54 (20130101)
A61K 2039/507 (20130101)
A61K 2039/5152 (20130101)
A61K 2039/55516 (20130101)
A61K 2039/55522 (20130101)
A61K 2039/55561 (20130101)

Peptides
C07K 16/30 (20130101)
C07K 16/2803 (20130101)
C07K 16/2818 (20130101)
C07K 16/3053 (20130101)
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998600 Brooks et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Center for Research Resources (NCRR)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) MaineHealth (Scarborough, Maine)
ASSIGNEE(S) MaineHealth (Scarborough, Maine)
INVENTOR(S) Peter C. Brooks (Harpswell, Maine);  Jennifer M. Caron (Scarborough, Maine);  Liangru Contois (Yarmouth, Maine)
ABSTRACT The present invention provides antagonists and methods of use thereof in the treatment of cancer and abnormal immune suppression diseases.
FILED Thursday, December 03, 2020
APPL NO 17/110543
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/39 (20130101)
A61K 39/3955 (20130101) Original (OR) Class
A61K 39/39558 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)
A61K 2039/507 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
A61P 37/04 (20180101)

Peptides
C07K 14/78 (20130101)
C07K 16/18 (20130101)
C07K 16/2827 (20130101)
C07K 2317/34 (20130101)
C07K 2317/70 (20130101)
C07K 2317/73 (20130101)
C07K 2317/76 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998602 Lairson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute on Drug Abuse (NIDA)
National Institute of General Medical Sciences (NIGMS)
NIH Office of the Director (NIHOD)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Luke Lairson (San Diego, California);  Brittney Beyer (San Diego, California);  Mingliang Fang (Singapore, Singapore);  Gary Siuzdak (Cardiff, California)
ABSTRACT This invention provides novel methods for treating or ameliorating symptoms of demyelinating diseases such as multiple sclerosis. The methods involve administering to subjects in need of treatment a pharmaceutical composition that contains a therapeutically effective amount of taurine and also a compound that induces oligodendrocyte precursor cell (OPC) differentiation (e.g., T3, benztropine, clemastine or miconazole). Some of the methods additionally involve administration to the subject a known agent for treating demyelinating diseases (e.g., SIP receptor agonists) or a known disease modifying drug. The invention also provides methods for increasing myelination and methods for promoting OPC differentiation into oligodendrocytes. These methods entail contacting a population of OPCs with a combination of taurine and a known OPC differentiation-inducing agent such as T3, clemastine, benztropine or miconazole.
FILED Tuesday, November 13, 2018
APPL NO 16/978558
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 303/02 (20130101)

Peptides
C07K 16/286 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998615 Santa Maria et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Peter Luke Santa Maria (Redwood City, California);  Laurent Bekale (Redwood City, California)
ABSTRACT Compositions, methods, and kits are provided for treating bacterial infections with nanoparticles comprising a thiol-binding metallic core conjugated to a fluoroquinolone antibiotic. Recalcitrant infections are often difficult to treat because of the presence of persister cells, a subpopulation of bacterial cells that is highly tolerant of traditional antibiotics. Persister cells are dormant, which makes them less susceptible to many antibiotics, which are designed to kill growing cells. Administration of nanoparticles comprising a thiol-binding metallic core conjugated to fluoroquinolone antibiotics was found to be highly efficacious in eradicating persister cells and for treating infections for a broad range of bacterial species, including Gram-positive and Gram-negative bacteria. Such treatment was effective not only in eradicating planktonic bacteria but also bacteria in biofilms.
FILED Wednesday, April 13, 2022
APPL NO 17/719727
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/60 (20170801)
A61K 47/6929 (20170801) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998616 Davis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Mark E. Davis (Pasadena, California);  Emily A. Wyent (Sherman Oaks, California)
ABSTRACT The present application discloses nanoparticles carrying therapeutic agents, including chemotherapeutic agents, and targeting ligands suitable for delivering these therapeutic agents through the blood brain barrier and methods of using these patients on those patients in need of such treatment.
FILED Monday, March 29, 2021
APPL NO 17/215443
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1641 (20130101)
A61K 31/137 (20130101)
A61K 31/4045 (20130101)
A61K 31/4745 (20130101)
A61K 47/6935 (20170801) Original (OR) Class

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Peptides
C07K 16/32 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/773 (20130101)
Y10S 977/906 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998635 Leonard et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Joshua N. Leonard (Wilmette, Illinois);  Michelle E. Hung (Chicago, Illinois)
ABSTRACT Disclosed are extracellular vesicles comprising an engineered targeting protein for targeting the extracellular vesicles to target cells. The targeting protein is a fusion protein that includes a ligand, an engineered glycosylation site, and an exosome-targeting domain. Exemplary extracellular vesicles may include but are not limited to exosomes.
FILED Monday, April 20, 2020
APPL NO 16/852894
ART UNIT 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/1075 (20130101) Original (OR) Class
A61K 31/713 (20130101)
A61K 47/46 (20130101)

Peptides
C07K 14/70596 (20130101)
C07K 2319/03 (20130101)
C07K 2319/06 (20130101)
C07K 2319/74 (20130101)
C07K 2319/85 (20130101)
C07K 2319/91 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/88 (20130101)
C12N 2740/16043 (20130101)
C12N 2810/6081 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998642 Bayley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Oxford University Innovation Limited (Oxford, United Kingdom)
ASSIGNEE(S) Oxford University Innovation Limited (Oxford, United Kingdom)
INVENTOR(S) John Hagan Pryce Bayley (Oxford, United Kingdom);  Andrew Heron (Oxford, United Kingdom);  Gabriel Villar (Oxford, United Kingdom)
ABSTRACT The invention provides a droplet encapsulate comprising: a drop of a hydrophobic medium; a peripheral layer of non-polymeric amphipathic molecules around the surface of the drop; and an aqueous droplet within the peripheral layer, the aqueous droplet comprising: (a) an aqueous medium and (b) an outer layer of non-polymeric amphipathic molecules around the surface of the aqueous medium. The invention also provides processes for preparing the droplet encapsulates. Various uses of the droplet encapsulates are also described, including their use as drug delivery vehicles, in synthetic biology, and in the study of membrane proteins.
FILED Wednesday, June 29, 2022
APPL NO 17/853000
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/50 (20130101) Original (OR) Class
A61K 9/113 (20130101)
A61K 9/1075 (20130101)
A61K 9/1271 (20130101)
A61K 31/085 (20130101)
A61K 49/0002 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/02 (20130101)
B01J 13/025 (20130101)

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 67/0097 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/2984 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998657 Jiang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Hongbin Jiang (Export, Pennsylvania);  William R. Wagner (Gibsonia, Pennsylvania);  Tomo Yoshizumi (Pittsburgh, Pennsylvania);  Yang Zhu (Pittsburgh, Pennsylvania)
ABSTRACT Provided are novel biocompatible copolymers, compositions comprising the copolymers, and methods of using the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodible in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers.
FILED Thursday, August 05, 2021
APPL NO 17/394984
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0024 (20130101)
A61K 47/30 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/16 (20130101) Original (OR) Class
A61L 27/52 (20130101)
A61L 27/54 (20130101)
A61L 2300/414 (20130101)
A61L 2400/06 (20130101)
A61L 2430/20 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 220/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998658 Jeong
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of New Hampshire (Durham, New Hampshire)
ASSIGNEE(S) University of New Hampshire (Durham, New Hampshire)
INVENTOR(S) Kyung Jae Jeong (Durham, New Hampshire)
ABSTRACT Injectable macroporous hydrogels, and methods of producing same, are described. The injectable macroporous hydrogels may be formed by mixing gelatin microgels with an enzyme. In at least some embodiments, the enzyme may be transglutaminase, and more specifically microbial transglutaminase (mTG).
FILED Monday, February 10, 2020
APPL NO 16/786312
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/52 (20130101)
A61L 27/222 (20130101) Original (OR) Class
A61L 27/3687 (20130101)
A61L 27/3834 (20130101)
A61L 2400/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998673 Epshteyn et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Nuwellis, Inc. (Eden Prairie, Minnesota)
ASSIGNEE(S) NUWELLIS, INC. (Eden Prairie, Minnesota)
INVENTOR(S) Vitaliy Gennad'yevich Epshteyn (Maple Grove, Minnesota);  Steven Daniel Sandoval (Eden Prairie, Minnesota);  Kalley Francis Berg (Lino Lakes, Minnesota);  Franz Willems Ulrich (Minneapolis, Minnesota)
ABSTRACT An extracorporeal blood filtering machine can include a blood circuit, an effluent circuit, and a source fluid circuit and can be controlled by a controller. The extracorporeal blood filtering machine can also include access ports for connecting the source fluid circuit to the blood circuit, as well as blood sensors to detect possible issues with the extracorporeal blood filtering machine. The extracorporeal blood filtering machine can include density sensors and flow sensors that enable it to be more accurate and to operate while being transported. The extracorporeal blood filtering machine can further include a user interface and can display fluid inflow/outflow information. A medical fluid container can automatically empty after being filled. An apparatus for supporting a medical fluid container can include a hanger and an attachment member with the apparatus able to adjust to ensure the medical fluid container remains properly oriented directly under a medical fluid container scale.
FILED Monday, February 20, 2023
APPL NO 18/171640
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 1/14 (20130101)
A61M 1/34 (20130101) Original (OR) Class
A61M 1/154 (20220501)
A61M 1/155 (20220501)
A61M 1/341 (20140204)
A61M 1/342 (20130101)
A61M 1/1562 (20220501)
A61M 1/1566 (20220501)
A61M 1/3413 (20130101)
A61M 1/3424 (20140204)
A61M 1/3434 (20140204)
A61M 1/3437 (20140204)
A61M 1/3441 (20130101)
A61M 1/3444 (20140204)
A61M 1/3451 (20140204)
A61M 1/3607 (20140204)
A61M 1/3624 (20130101)
A61M 1/3663 (20130101)
A61M 1/15632 (20220501)
A61M 1/36224 (20220501)
A61M 1/36225 (20220501)
A61M 1/362262 (20220501)
A61M 1/362264 (20220501)
A61M 1/362266 (20220501)
A61M 60/109 (20210101)
A61M 60/268 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998757 Lohr et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin)
ASSIGNEE(S) The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin)
INVENTOR(S) Nicole Lohr (New Berlin, Wisconsin);  Michael Salinger (, None)
ABSTRACT Reperfusion injury is limited during endovascular therapies (e.g., revascularization and/or reperfusion of end organ tissues) by conditioning the tissues against reperfusion injury using an optical fiber catheter to deliver far red and near infrared (R/NIR) light to the tissues. The light may be multiple wavelength or single wavelength light, and may have one or more wavelengths selected from the range of 510 to 830 nm. The R/NIR light may be delivered concurrently with the endovascular therapy, or in other instances may be delivered before or after a particular therapy.
FILED Tuesday, March 22, 2022
APPL NO 17/701099
ART UNIT 3796 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/24 (20130101)
A61B 2017/0019 (20130101)
A61B 2018/00351 (20130101)
A61B 2018/00577 (20130101)
A61B 2090/049 (20160201)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/0601 (20130101) Original (OR) Class
A61N 5/0613 (20130101)
A61N 2005/063 (20130101)
A61N 2005/0602 (20130101)
A61N 2005/0651 (20130101)
A61N 2005/0663 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998762 Berbeco et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The Brigham and Women's Hospital, Inc. (Boston, Massachusetts)
INVENTOR(S) Ross Berbeco (Cohasset, Massachusetts);  Yue-Houng Hu (Rochester, Minnesota)
ABSTRACT Some aspects of the disclosure provide a radiation therapy system. The system can include a radiation source configured to emit a radiation therapy beam, a collimator positioned to attenuate at least a periphery of the radiation therapy beam, a radiation fiducial marker configured to be coupled to a patient, and a first radiation detector and a second radiation detector configured to receive the radiation therapy beam after passing through a patient. The system also includes a computer configured to determine a position of the radiation fiducial marker using information from the first detector and the second detector.
FILED Monday, December 07, 2020
APPL NO 17/114077
ART UNIT 2884 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/4266 (20130101)
A61B 90/39 (20160201)
A61B 2090/3937 (20160201)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1045 (20130101)
A61N 5/1049 (20130101)
A61N 5/1077 (20130101) Original (OR) Class

Measurement of Nuclear or X-radiation
G01T 1/2018 (20130101)
G01T 1/2023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998861 Andrews et al.
FUNDED BY
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
APPLICANT(S) Velico Medical, Inc. (Beverly, Massachusetts)
ASSIGNEE(S) Velico Medical, Inc. (Beverly, Massachusetts)
INVENTOR(S) Robert R. Andrews (Norfolk, Massachusetts);  Herman E. Snyder (W. Lafayette, Indiana);  William J. Merritt (Danvers, Massachusetts);  Kyle D. Erickson (Melrose, Massachusetts);  Evan P. Ordway (Salem, Massachusetts);  Clair Strohl (Emmaus, Pennsylvania);  Russell Barron (Boston, Massachusetts)
ABSTRACT The present invention includes an ease-of-use system that allows the spray drying disposable device to fit (e.g., align) in both spray drying apparatus and the spray drying finishing apparatus to safely operate the system. The system includes locating arrangements between the spray drying disposable and the spray drying apparatus and/or spray drying finishing apparatus, a first retainer and second retainer, a shorter disposable device that allows for effective spray drying of plasma, a feedback indicators of correct installment, redundant indicators of correct installment, easily accessible operator controls and emergency shut offs.
FILED Thursday, September 15, 2022
APPL NO 17/945129
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 1/18 (20130101) Original (OR) Class

Drying Solid Materials or Objects by Removing Liquid Therefrom
F26B 3/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998912 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Tza-Huei Jeff Wang (Germantown, Maryland);  Kuangwen Hsieh (Baltimore, Maryland);  Yi-Fan Frank Hsieh (New Taipei, Taiwan);  Aniruddha Mrithinjay Kaushik (Baltimore, Maryland);  Fangchi Shao (Baltimore, Maryland);  Pengfei Zhang (Baltimore, Maryland)
ABSTRACT A tubing-free, sample-to-droplet microfluidic system includes a tubing-free, sample-to-droplet microfluidic chip; a valve control system connected to the tubing-free, sample-to-droplet microfluidic chip; a vacuum system fluidly connected to the tubing-free, sample-to-droplet microfluidic chip; and a droplet formation pressure system fluidly connected to the tubing-free, sample-to-droplet microfluidic chip. A microfluidic chip for a tubing-free, sample-to-droplet microfluidic system includes a tubing-free, sample-to-droplet interface section; a droplet mixing section in fluid connection with the tubing-free, sample-to-droplet interface section to received droplets therefrom; an incubation section in fluid connection with the droplet mixing section to receive droplets therefrom; and a detection section in fluid connection with the incubation section to receive droplets therefrom.
FILED Tuesday, September 27, 2022
APPL NO 17/954000
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502738 (20130101) Original (OR) Class
B01L 2300/0636 (20130101)
B01L 2300/0883 (20130101)
B01L 2400/02 (20130101)
B01L 2400/049 (20130101)
B01L 2400/0666 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1697 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999638 Ball
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) OXYTEC LLC (Newton, Massachusetts)
ASSIGNEE(S) OXYTEC LLC (Newton, Massachusetts)
INVENTOR(S) Raymond G. Ball (Newton, Massachusetts)
ABSTRACT Disclosed are methods, apparatuses and systems for the remediation of contaminated soils, groundwater, water, and/or waste using a combination of reagents. The disclosed methods may be used to treat various recalcitrant halogenated substances, such as perfluoroalkyls and polyfluoroalkyls. Particular combinations of reagents that may be used in the disclosed methods include but are not limited to: (1) persulfate, oxygen and ozone; (2) persulfate, salt, oxygen and ozone; (3) persulfate, phosphate, and/or oxygen; (4) persulfate, phosphate, oxygen and ozone; (5) persulfate, phosphate, salt and oxygen (6) persulfate, phosphate, salt, oxygen and ozone; (7) oxygen and salt; and (8) air and salt. The disclosed methods may enhance destruction of organic contaminants in the liquid phase and may also control the rate of aerosol or foam formation relative to the rate of chemical oxidation and/or reduction/transfer.
FILED Friday, September 15, 2023
APPL NO 18/467812
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Reclamation of Contaminated Soil
B09C 1/002 (20130101)
B09C 1/06 (20130101)
B09C 1/08 (20130101)
B09C 2101/00 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/32 (20130101)
C02F 1/70 (20130101)
C02F 1/78 (20130101)
C02F 1/722 (20130101) Original (OR) Class
C02F 1/725 (20130101)
C02F 1/727 (20130101)
C02F 2101/34 (20130101)
C02F 2101/36 (20130101)
C02F 2101/305 (20130101)
C02F 2101/306 (20130101)
C02F 2101/322 (20130101)
C02F 2101/327 (20130101)
C02F 2101/363 (20130101)
C02F 2103/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999677 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) Weidong Wang (Edmond, Oklahoma);  Venkateswararao Eeda (Oklahoma City, Oklahoma)
ABSTRACT Benzylamino-oxoethyl benzamide compounds for use in treating diseases and conditions associated with abnormal cell function related to endoplasmic reticulum (ER) stress. For example, the compounds can be used as suppressors of ER stress-induced pancreatic β-cell dysfunction and death, for example in the treatment of Type 1 and Type 2 diabetes. The compounds can also be used in treatments for chronic heart disease, neurodegenerative diseases, retinal degeneration, and other metabolic disorders associated with ER stress.
FILED Tuesday, February 08, 2022
APPL NO 17/666692
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 233/73 (20130101) Original (OR) Class

Heterocyclic Compounds
C07D 317/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999693 Edinger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California);  The Université de Montréal (Montreal, Canada)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Aimee L. Edinger (Irvine, California);  Stephen Hanessian (Irvine, California)
ABSTRACT Small molecules comprised of azacyclic constrained sphingolipid-like compounds and methods of their synthesis are provided. Formulations and medicaments are also provided that are directed to the treatment of disease, such as, for example, neoplasms, cancers, and other diseases. Therapeutics are also provided containing a therapeutically effective dose of one or more small molecule compounds, present either as pharmaceutically effective salt or in pure form, including, but not limited to, formulations for oral, intravenous, or intramuscular administration.
FILED Thursday, October 13, 2022
APPL NO 18/046471
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/40 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 207/06 (20130101)
C07D 207/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999716 Lee et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
Frederick National Laboratory for Cancer Research (FNLCR)
Federally Funded Research and Development Center (FFRDC)
Operated by Leidos Biomedical Research, Inc. (LBRI) at Frederick, MD
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) Vanderbilt University (Nashville, Tennessee)
INVENTOR(S) Taekyu Lee (Brentwood, Tennessee);  Joseph R. Alvarado (Cleveland Heights, Ohio);  Jianhua Tian (Nashville, Tennessee);  Kenneth M. Meyers (Nashville, Tennessee);  Changho Han (Nashville, Tennessee);  Jonathan J. Mills (Nashville, Tennessee);  Kevin B. Teuscher (Nashville, Tennessee);  Shaun R. Stauffer (Brentwood, Tennessee);  Stephen W. Fesik (Nashville, Tennessee);  Rocco D. Gogliotti (Kingston Springs, Tennessee)
ABSTRACT Isoquinolinone compounds and derivatives inhibit WDR5 and associated protein-protein interactions, and the compounds and their pharmaceutical compositions are useful for treating disorders and conditions in a subject, such as cancer cell proliferation.
FILED Thursday, October 24, 2019
APPL NO 17/287492
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 217/16 (20130101)
C07D 401/06 (20130101)
C07D 401/14 (20130101) Original (OR) Class
C07D 405/14 (20130101)
C07D 413/06 (20130101)
C07D 413/14 (20130101)
C07D 417/06 (20130101)
C07D 417/14 (20130101)
C07D 487/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999720 Meroueh et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana);  THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S) THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana);  THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Samy Meroueh (Carmel, Indiana);  Fletcher A. White (Indianapolis, Indiana);  Alexander G. Obukhov (Carmel, Indiana)
ABSTRACT This invention relates to pyrazolylacylpyrazoline compounds or pharmaceutically acceptable salts thereof, and for the use of the compounds to treat neurological disorders.
FILED Thursday, September 19, 2019
APPL NO 17/251473
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 401/14 (20130101)
C07D 403/04 (20130101) Original (OR) Class
C07D 403/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999723 Jorgensen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) YALE UNIVERSITY (New Haven, Connecticut)
ASSIGNEE(S) YALE UNIVERSITY (New Haven, Connecticut)
INVENTOR(S) William L. Jorgensen (Deep River, Connecticut);  Vinay Trivedi-Parmar (Boston, Massachusetts)
ABSTRACT In one aspect, the invention comprises compounds that bind and inhibit macrophage migration inhibitory factor. In another aspect, the invention provides methods of treating, ameliorating, and/or preventing inflammatory disease, neurological disorders and cancer using the compounds of the invention.
FILED Monday, August 29, 2022
APPL NO 17/897961
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 231/12 (20130101)
C07D 231/16 (20130101)
C07D 405/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999747 An et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as Represented by the Secretary, Dept of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Linkun An (Guangzhou, China PRC);  Christophe Marchand (Silver Spring, Maryland);  Yves Pommier (Bethesda, Maryland)
ABSTRACT Compounds of Formula I and the pharmaceutically acceptable salts thereof are disclosed The variables X1, X2, and R1-4 are disclosed herein. The compounds are useful for treating cancer and related proliferative diseases. Pharmaceutical compositions containing compounds of Formula I and methods of treatment comprising administering compounds of Formula I are also disclosed.
FILED Monday, January 11, 2021
APPL NO 17/146327
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/47 (20130101)
A61K 31/47 (20130101)
A61K 31/122 (20130101)
A61K 31/122 (20130101)
A61K 31/136 (20130101)
A61K 31/136 (20130101)
A61K 31/194 (20130101)
A61K 31/194 (20130101)
A61K 31/343 (20130101)
A61K 31/473 (20130101)
A61K 31/473 (20130101)
A61K 31/475 (20130101)
A61K 31/475 (20130101)
A61K 31/496 (20130101)
A61K 31/498 (20130101)
A61K 31/498 (20130101)
A61K 31/704 (20130101)
A61K 31/704 (20130101)
A61K 31/4741 (20130101)
A61K 31/4745 (20130101)
A61K 31/5377 (20130101)
A61K 31/7048 (20130101)
A61K 31/7048 (20130101)
A61K 45/06 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Heterocyclic Compounds
C07D 221/08 (20130101)
C07D 307/92 (20130101)
C07D 471/04 (20130101)
C07D 491/04 (20130101)
C07D 491/048 (20130101) Original (OR) Class
C07D 498/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999767 Zhang
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Feng Zhang (Cambridge, Massachusetts)
ABSTRACT The disclosure provides novel programmable targeting sequences and applications thereof. The targeting sequences can be engineered for binding to proteins, polypeptides, and other macromolecules.
FILED Wednesday, December 23, 2020
APPL NO 17/133141
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/24 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 15/1086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999777 Ganguly et al.
FUNDED BY
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
APPLICANT(S) Regeneron Pharmaceuticals, Inc. (Tarrytown, New York)
ASSIGNEE(S) Regeneron Pharmaceuticals, Inc. (Tarrytown, New York)
INVENTOR(S) Samit Ganguly (Elmsford, New York);  Jennifer Hamilton (Ridgefield, Connecticut);  Gary Herman (Princeton, New Jersey);  Andrea Hooper (Port Chester, New York);  Flonza Isa (Yonkers, New York);  Meagan O'Brien (New York, New York);  Sumathi Sivapalasingam (Brooklyn, New York);  Kenneth Turner (Ridgefield, Connecticut);  Eduardo Forleo Neto (Greenwich, Connecticut)
ABSTRACT The present invention provides methods for preventing and treating SARS-CoV-2 infections, COVID-19, or symptoms thereof. The methods of the invention feature the administration of one or more antigen-binding molecules (e.g., antibodies) that bind a surface protein of SARS-CoV-2 (e.g., spike protein).
FILED Wednesday, June 02, 2021
APPL NO 17/337396
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 31/706 (20130101)
A61K 39/42 (20130101)
A61K 45/06 (20130101)
A61K 2039/54 (20130101)
A61K 2039/507 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 16/10 (20130101) Original (OR) Class
C07K 16/2866 (20130101)
C07K 2317/33 (20130101)
C07K 2317/76 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999794 Beatty et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Novartis AG (Basel, Switzerland);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) Novartis AG (Basel, Switzerland);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Gregory Beatty (Philadelphia, Pennsylvania);  Boris Engels (Arlington, Massachusetts);  Neeraja Idamakanti (Burlington, Massachusetts);  Carl H. June (Merion Station, Pennsylvania);  Andreas Loew (Boston, Massachusetts);  Huijuan Song (Shanghai, China PRC);  Qilong Wu (Brighton, Massachusetts)
ABSTRACT Provided are compositions and methods for treating diseases associated with expression of mesothelin. Also provided are a chimeric antigen receptor (CAR) specific to mesothelin, vectors encoding the same, and recombinant T cells comprising the mesothelin CAR. Further provided are methods of administering a genetically modified T cell expressing a CAR that comprises a mesothelin binding domain.
FILED Thursday, January 23, 2020
APPL NO 16/750951
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/436 (20130101)
A61K 38/00 (20130101)
A61K 38/1774 (20130101)
A61K 38/1793 (20130101)
A61K 39/001168 (20180801)
A61K 39/39558 (20130101)
A61K 48/0058 (20130101)
A61K 2039/505 (20130101)
A61K 2039/5158 (20130101)

Peptides
C07K 14/7051 (20130101)
C07K 14/7151 (20130101)
C07K 14/70517 (20130101)
C07K 16/30 (20130101) Original (OR) Class
C07K 16/303 (20130101)
C07K 16/3061 (20130101)
C07K 16/3069 (20130101)
C07K 2317/73 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
C07K 2317/622 (20130101)
C07K 2319/00 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/74 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0638 (20130101)
C12N 15/85 (20130101)
C12N 15/86 (20130101)
C12N 2740/15041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999796 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America,as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Qiong J. Wang (Potomac, Maryland);  Zhiya Yu (Potomac, Maryland);  James C. Yang (Bethesda, Maryland)
ABSTRACT The invention provides a chimeric antigen receptor (CAR) having antigenic specificity for CD70, the CAR comprising: an antigen binding—transmembrane domain comprising a CD27 amino acid sequence lacking all or a portion of the CD27 intracellular T cell signaling domain; a 4-1BB intracellular T cell signaling domain; a CD3ζ intracellular T cell signaling domain; and optionally, a CD28 intracellular T cell signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed.
FILED Friday, June 19, 2020
APPL NO 16/906061
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/7051 (20130101)
C07K 14/7153 (20130101)
C07K 14/70517 (20130101)
C07K 14/70521 (20130101)
C07K 14/70578 (20130101)
C07K 16/30 (20130101) Original (OR) Class
C07K 16/2875 (20130101)
C07K 2317/60 (20130101)
C07K 2317/622 (20130101)
C07K 2319/00 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999799 Baum et al.
FUNDED BY
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
APPLICANT(S) Regeneron Pharmaceuticals, Inc. (Tarrytown, New York)
ASSIGNEE(S) REGENERON PHARMACEUTICALS, INC. (Tarrytown, New York)
INVENTOR(S) Alina Baum (Pleasantville, New York);  Christos Kyratsous (Irvington, New York);  Lisa Purcell (Yorktown Heights, New York)
ABSTRACT The present disclosure provides antibodies and antigen-binding fragments thereof that bind specifically to TMPRSS2 and methods of using such antibodies and fragments for treating or preventing viral infections (e.g., coronavirus infections or influenza virus infections).
FILED Tuesday, February 09, 2021
APPL NO 17/171941
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/3955 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 16/40 (20130101) Original (OR) Class
C07K 2317/31 (20130101)
C07K 2317/33 (20130101)
C07K 2317/92 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999803 Kim
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) University of Kentucky Research Foundation (Lexington, Kentucky)
ASSIGNEE(S) University of Kentucky Research Foundation (Lexington, Kentucky)
INVENTOR(S) Kyung Bo Kim (Lexington, Kentucky)
ABSTRACT Unique compounds useful for inhibiting a proteasome in a cell, pharmaceutical compositions and methods of their use are provided herein.
FILED Tuesday, February 14, 2023
APPL NO 18/169158
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)

Peptides
C07K 5/123 (20130101) Original (OR) Class
C07K 5/126 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999853 Helgason et al.
FUNDED BY
Department of Veterans Affairs (DVA)
DVA Office of Research and Development (DVAORD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Non-Profit Organization (NPO)
Dystrophic Epidermolysis Bullosa Research Association of America (DEBRA of America)
APPLICANT(S) VitroLabs Inc (Milpitas, California);  King's College London (London, United Kingdom)
ASSIGNEE(S) VITROLABS INC (Milpitas, California);  KING'S COLLEGE LONDON (London, United Kingdom)
INVENTOR(S) Ingvar Helgason (South San Francisco, California);  Dusko Ilic (London, United Kingdom)
ABSTRACT Disclosed herein are synthetic leathers, artificial epidermal layers, artificial dermal layers, layered structures, products produced therefrom and methods of producing the same.
FILED Wednesday, July 05, 2023
APPL NO 18/347349
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compositions of Macromolecular Compounds
C08L 89/06 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0625 (20130101)
C12N 5/0629 (20130101)
C12N 5/0698 (20130101)
C12N 11/02 (20130101)
C12N 2501/155 (20130101)
C12N 2501/385 (20130101)
C12N 2502/13 (20130101)
C12N 2502/091 (20130101)
C12N 2502/094 (20130101)
C12N 2506/45 (20130101)
C12N 2533/30 (20130101)
C12N 2533/54 (20130101)

Chemical Treatment of Hides, Skins or Leather, e.g Tanning, Impregnating, Finishing; Apparatus Therefor; Compositions for Tanning
C14C 3/02 (20130101)
C14C 13/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999948 Olsen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Hugh E. Olsen (Davis, California);  Miten Jain (Santa Cruz, California);  Mark A. Akeson (Santa Cruz, California)
ABSTRACT Provided are methods of producing size-selected nucleic acid libraries. The methods include contacting a nucleic acid sample and a nucleic acid binding reagent including an affinity tag, under conditions in which nucleic acids of less than a desired length are substantially bound to the nucleic acid binding reagent and nucleic acids of the desired length are substantially not bound to the nucleic acid binding reagent. The conditions include the duration of the contacting, the concentration of the nucleic acid binding reagent, or both. The methods further include separating, using the affinity tag, the nucleic acids of less than the desired length bound to the nucleic acid binding reagent from the nucleic acids of the desired length not bound to the nucleic acid binding reagent, to produce a size-selected nucleic acid library. Compositions and kits that find use, e.g., in practicing the methods of the present disclosure, are also provided.
FILED Thursday, May 03, 2018
APPL NO 15/970690
ART UNIT 1675 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 2219/005 (20130101)
B01J 2219/00454 (20130101)
B01J 2219/00677 (20130101)
B01J 2219/00722 (20130101)
B01J 2219/00759 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/11 (20130101)
C12N 15/1065 (20130101) Original (OR) Class
C12N 15/1068 (20130101)
C12N 15/1093 (20130101)
C12N 15/1093 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 2537/159 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 30/04 (20130101)
C40B 40/06 (20130101)
C40B 70/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999951 Shendure et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Washington Through Its Center for Commercialization (Seattle, Washington)
ASSIGNEE(S) University of Washington through its Center for Commercialization (Seattle, Washington)
INVENTOR(S) Jay Ashok Shendure (Seattle, Washington);  Jerrod Joseph Schwartz (Seattle, Washington);  Andrew Colin Adey (Seattle, Washington);  Cho li Lee (Seattle, Washington);  Joseph Brian Hiatt (Seattle, Washington);  Jacob Otto Kitzman (Seattle, Washington);  Akash Kumar (Seattle, Washington)
ABSTRACT Contiguity information is important to achieving high-quality de novo assembly of mammalian genomes and the haplotype-resolved resequencing of human genomes. The methods described herein pursue cost-effective, massively parallel capture of contiguity information at different scales.
FILED Friday, April 08, 2022
APPL NO 17/716539
ART UNIT 1675 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1093 (20130101) Original (OR) Class

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 20/582 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999954 Han et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
APPLICANT(S) CITY OF HOPE (Duarte, California);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) Clty of Hope (Duarte, California);  California Institute of Technology (Pasadena, California)
INVENTOR(S) Si-ping Han (Duarte, California);  William A. Goddard, III (Pasadena, California);  Marwa Ben Haj Salah (Duarte, California);  Lisa Scherer (Duarte, California);  John J. Rossi (Duarte, California)
ABSTRACT Disclosed herein are programmable, conditionally activated small interfering RNA constructs (Cond-siRNAs) and methods of making and using the same as therapeutic agents. The Cond-siRNA comprises a sensor strand, a core strand, and a guide strand, which crossover to form a sensor duplex and a RNAi duplex attached to each other to form a single structure. Upon binding an input strand to the sensor strand, the Cond-siRNA is activated and releases RNAi targeting a desired gene.
FILED Wednesday, February 10, 2021
APPL NO 17/172461
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/141 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999965 Yan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Iowa Research Foundation (Iowa City, Iowa);  University of Kansas (Lawrence, Kansas)
ASSIGNEE(S) University of Iowa Research Foundation (Iowa City, Iowa);  University of Kansas (Lawrence, Kansas)
INVENTOR(S) Ziying Yan (Iowa City, Iowa);  John F. Engelhardt (Iowa City, Iowa);  Jianming Qiu (Overland Park, Kansas);  Zekun Wang (Kansas City, Kansas)
ABSTRACT Vectors having a nucleotide sequence having SEQ ID NO:1 or a nucleotide sequence having at least 85% identity to SEQ ID NO:1, or a portion thereof, that is capable of regulating bocaparvovirus replication, or vectors having the complement of the nucleotide sequence, and methods of using the vectors, are provided.
FILED Thursday, September 09, 2021
APPL NO 17/470560
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/23 (20130101)
A61K 2039/53 (20130101)
A61K 2039/5256 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/20 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2750/14121 (20130101)
C12N 2750/14134 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14322 (20130101)
C12N 2750/14344 (20130101)
C12N 2750/14362 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999995 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Tina Wang (San Diego, California);  Trey Ideker (San Diego, California)
ABSTRACT The disclosure provides for methylome profiling of animals and further using DNA methylation as a quantitative predictor of the age of an animal.
FILED Friday, August 31, 2018
APPL NO 16/638454
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/6855 (20130101) Original (OR) Class
C12Q 2523/125 (20130101)
C12Q 2535/122 (20130101)
C12Q 2537/143 (20130101)
C12Q 2600/154 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999999 Ju et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Jingyue Ju (Englewood Cliffs, New Jersey);  Xiaoxu Li (New York, New York);  Xin Chen (New York, New York);  Zengmin Li (Flushing, New York);  Shiv Kumar (Belle Meade, New Jersey);  Shundi Shi (Ozone Park, New York);  Cheng Guo (Brooklyn, New York);  Jianyi Ren (New York, New York);  Min-Kang Hsieh (New York, New York);  Minchen Chien (Tenafly, New Jersey);  Chuanjuan Tao (Fort Lee, New Jersey);  Ece Erturk (New York, New York);  Sergey Kalachikov (Bronx, New York);  James J. Russo (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Jingyue Ju (Englewood Cliffs, New Jersey);  Xiaoxu Li (New York, New York);  Xin Chen (New York, New York);  Zengmin Li (Flushing, New York);  Shiv Kumar (Belle Meade, New Jersey);  Shundi Shi (Ozone Park, New York);  Cheng Guo (Brooklyn, New York);  Jianyi Ren (New York, New York);  Min-Kang Hsieh (New York, New York);  Minchen Chien (Tenafly, New Jersey);  Chuanjuan Tao (Fort Lee, New Jersey);  Ece Erturk (New York, New York);  Sergey Kalachikov (Bronx, New York);  James J. Russo (New York, New York)
ABSTRACT Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.
FILED Monday, July 12, 2021
APPL NO 17/373295
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 19/10 (20130101)
C07H 19/14 (20130101)
C07H 19/20 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6869 (20130101) Original (OR) Class
C12Q 1/6869 (20130101)
C12Q 2525/117 (20130101)
C12Q 2563/107 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000003 Yeh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
ASSIGNEE(S) The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina)
INVENTOR(S) Jen Jen Yeh (Chapel Hill, North Carolina);  Richard Moffitt (Stony Brook, New York);  Naim Ur Rashid (Raleigh, North Carolina)
ABSTRACT Provided are methods for identifying pancreatic cancer subtypes in a subject and treating the same. In some embodiments, the method comprise obtaining gene expression levels for each of the following genes in the biological sample: GPR87, KRT6A, BCAR3, PTGES, 1TGA3, C16orf74, S100A2, KRT5, REG4, ANXA10, GATA6, CLDN18, LGALS4, DDC, SLC40A1, CLRN3; performing pair-wise comparisons of gene expression levels for combinations of these genes, and calculating a Raw Score for the biological sample, wherein the Raw Score is indicative of the pancreatic cancer subtype in the subject. Also provided are methods for identifying differential treatment strategies for subjects diagnosed with PDAC, methods for treating PDAC patients based on the subtype of PD AC the patients have; and methods for classifying subjects diagnosed with PDAC as having a basal-like subtype or a classical subtype of PDAC.
FILED Wednesday, April 01, 2020
APPL NO 17/601002
ART UNIT 1672 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/106 (20130101)
C12Q 2600/112 (20130101)
C12Q 2600/158 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 25/00 (20190201)
G16B 25/10 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000830 Lipkin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Walter Ian Lipkin (New York, New York);  Nischay Mishra (New York, New York);  Thomas Briese (White Plains, New York);  Adrian Caciula (New York, New York)
ABSTRACT The current invention provides compositions, methods, and kits for detecting the exposure to and infection by certain viruses. Specifically, the current invention allows for the rapid differential serological detection of exposure to, and infection by viruses. In particular, the current invention allows for the rapid serological detection of exposure to, and infection by Zika virus (ZIKV).
FILED Friday, December 01, 2017
APPL NO 16/466161
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/76 (20130101)

Peptides
C07K 7/00 (20130101)
C07K 16/06 (20130101)
C07K 16/1081 (20130101)
C07K 2317/21 (20130101)
C07K 2317/34 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56983 (20130101) Original (OR) Class
G01N 2333/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000917 Zhou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
INVENTOR(S) Xiaohong Joe Zhou (Chicago, Illinois);  Zheng Zhong (Chicago, Illinois);  Meryem Muge Karaman (Chicago, Illinois)
ABSTRACT A system and method for producing a series of time-resolved magnetic resonance (MR) images is set forth. The system can perform method steps of encoding spatial information into an MRI signal by manipulating a phase of the MRI signal within an MRI system, generating and outputting a phase-encoded MRI signal over time by digitizing a plurality of time points in the MRI signal, repeating the generating and outputting step for a plurality of phase-encoded signals, each phase-encoded signal in synchrony with a trigger, producing a plurality of digitized time points, and reconstructing a series of time resolved MR images, each image of the series of MR images at one specific time point selected from the plurality of digitized time points for each phase-encoded step. Each image in the series of time-resolved MR images corresponding to a specific time point in a cyclic event.
FILED Tuesday, January 21, 2020
APPL NO 17/423729
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4824 (20130101) Original (OR) Class
G01R 33/5608 (20130101)
G01R 33/5611 (20130101)
G01R 33/5616 (20130101)
G01R 33/5673 (20130101)

Electric Digital Data Processing
G06F 7/588 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/50 (20220501)
H04L 9/0662 (20130101)
H04L 9/3239 (20130101)
H04L 9/3247 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000920 Eaton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) University of Denver (Denver, Colorado)
ASSIGNEE(S) University of Denver (Denver, Colorado)
INVENTOR(S) Gareth R. Eaton (Denver, Colorado);  Richard W. Quine (Littleton, Colorado)
ABSTRACT A simulated Hall probe, provide EPR coil driver, and/or perform a time-domain full scan sinusoidal deconvolution of EPR signals. The simulated Hall probe can return a Hall Effect voltage from a coil current that creates a magnetic field within a coil magnet and the reference current that would be fed to an actual Hall probe. From these values, the Hall Effective voltage can be determined which can be used to determine the magnetic field flux, which can then be used to regulate the magnetic field.
FILED Friday, September 13, 2013
APPL NO 14/419907
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 24/10 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 1/203 (20130101)
G01R 33/60 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 11998207 McWeeney et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) G.I. Windows, Inc. (Westwood, Massachusetts)
ASSIGNEE(S) G.I. Windows, Inc. (Westwood, Massachusetts)
INVENTOR(S) John McWeeney (Brighton, Massachusetts);  Marvin Ryou (Melrose, Massachusetts);  Padraig Cantillon-Murphy (Danvers, Massachusetts);  Jeffrey H. Lang (Danvers, Massachusetts);  Christopher Thompson (Needham, Massachusetts)
ABSTRACT Methods and apparatus for creating an anastomosis or fistula between the gallbladder and an adjacent organ are disclosed. First, a parent magnet, typically a permanent magnet, is deployed in the stomach, small intestine, or another organ adjacent to the gallbladder, and a mating daughter material is deployed in the gallbladder in order to create a magnet-compression anastomosis. The gallbladder may then be ablated or otherwise functionally inactivated through the anastomosis. Another aspect of the invention relates to an all-in-one surgical kit that contains all the necessary specialized tools for a surgeon to perform the procedure.
FILED Monday, October 14, 2019
APPL NO 16/600841
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/11 (20130101) Original (OR) Class
A61B 17/1114 (20130101)
A61B 2017/00818 (20130101)
A61B 2017/00876 (20130101)
A61B 2017/1117 (20130101)
A61B 2017/1132 (20130101)
A61B 2017/1139 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998334 Berthier et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) Tasso, Inc. (Seattle, Washington)
ASSIGNEE(S) Tasso, Inc. (Seattle, Washington)
INVENTOR(S) Erwin Berthier (Seattle, Washington);  Ben Casavant (Seattle, Washington);  Ben Moga (Soquel, California)
ABSTRACT The disclosed apparatus, systems and methods relate to the collection of bodily fluids through the use of gravity and microfluidic properties by way of a collector. The collector can make use of microfluidic networks connected to collection sites on the skin of a subject to gather and shuttle blood into a reservoir by a combination of capillary action and gravitational forces. The collected fluid is moved through the microfluidic networks and into the reservoir by a variety of approaches.
FILED Tuesday, May 18, 2021
APPL NO 17/323567
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/15113 (20130101)
A61B 5/15142 (20130101)
A61B 5/150022 (20130101)
A61B 5/150099 (20130101)
A61B 5/150251 (20130101)
A61B 5/150343 (20130101)
A61B 5/150358 (20130101) Original (OR) Class
A61B 5/150412 (20130101)
A61B 5/150503 (20130101)
A61B 5/150977 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 2400/0406 (20130101)
B01L 2400/0457 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998460 Sobinov et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) West Virginia University (Morgantown, West Virginia);  University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) WEST VIRGINIA UNIVERSITY (Morgantown, West Virginia);  UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburg, Pennsylvania)
INVENTOR(S) Anton Sobinov (Morgantown, West Virginia);  Sergiy Yakovenko (Morgantown, West Virginia);  Valeriya Gritsenko (Morgantown, West Virginia);  Matthew Boots (Morgantown, West Virginia);  Robert Gaunt (Pittsburgh, Pennsylvania);  Jennifer Collinger (Pittsburgh, Pennsylvania);  Lee Fisher (Pittsburgh, Pennsylvania)
ABSTRACT A system and method for controlling a device, such as a virtual reality (VR) and/or a prosthetic limb are provided. A biomimetic controller of the system comprises a signal processor and a musculoskeletal model. The signal processor processes M biological signals received from a residual limb to transform the M biological signals into N activation signals, where M and N are integers and M is less than N. The musculoskeletal model transforms the N activation signals into intended motion signals. A prosthesis controller transforms the intended motion signals into three or more control signals that are outputted from an output port of the prosthesis controller. A controlled device receives the control signals and performs one or more tasks in accordance with the control signals.
FILED Saturday, December 19, 2020
APPL NO 17/787701
ART UNIT 2623 — Selective Visual Display Systems
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/389 (20210101)
A61B 5/1107 (20130101)
A61B 5/4519 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/70 (20130101)
A61F 2/72 (20130101) Original (OR) Class
A61F 2/582 (20130101)
A61F 2002/704 (20130101)
A61F 2002/0894 (20130101)
A61F 2002/5066 (20130101)
A61F 2002/6827 (20130101)
A61F 2002/6872 (20130101)

Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 2230/605 (20130101)

Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 2230/605 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/1075 (20130101)

Electric Digital Data Processing
G06F 3/011 (20130101)
G06F 3/015 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998785 Peterson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
Combat Capabilities Development Command (CCDC)
Chemical Biological Center (CCDC CBC)
APPLICANT(S) U.S. Army Combat Capabilities Development Command, Chemical Biological Center (Apg, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Gregory W Peterson (Belcamp, Maryland);  Thomas H Epps (Newark, Delaware);  John M Landers (Riverton, New Jersey)
ABSTRACT A polymer-based material includes a polymeric binder and one or more porous active materials that adsorb, chemisorb, decompose, or a combination thereof, a hazardous chemical. The polymeric binder and the one or more porous active materials are combined to form a composite bead. The polymeric binder may include a polyurethane or a styrene-based block copolymer. The porous active materials may comprise metal-organic frameworks, metal oxides, metal hydroxides, and metal hydrates. The one or more porous active materials may be between 1 and 99 wt % of a total composite mass of the composite bead. Alternatively, the one or more porous active materials may be between 80 and 95 wt % of a total composite mass of the composite bead. The hazardous chemical may include a chemical warfare agent, a simulant of chemical warfare agents, and toxic industrial chemicals.
FILED Thursday, September 16, 2021
APPL NO 17/476478
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Devices, Apparatus or Methods for Life-saving
A62B 17/006 (20130101)
A62B 18/088 (20130101)

Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus
A62D 3/33 (20130101) Original (OR) Class
A62D 3/35 (20130101)
A62D 3/38 (20130101)
A62D 5/00 (20130101)
A62D 2101/02 (20130101)
A62D 2101/08 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 3/20 (20130101)
C08J 2325/08 (20130101)
C08J 2375/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998883 Cauley, III et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) TALIS BIOMEDICAL CORPORATION (Chicago, Illinois)
ASSIGNEE(S) Talis Biomedical Corporation (Chicago, Illinois)
INVENTOR(S) Thomas H. Cauley, III (Redwood City, California);  David A. Rolfe (San Francisco, California)
ABSTRACT This disclosure relates to a magnetic mixing apparatus that mixes a sample contained in a mixing chamber using a stir bar, while minimizing the amount of contact between the stir bar and walls of the mixing chamber. In one aspect, the apparatus comprises a ferromagnetic stir bar contained in the mixing chamber, and a driving magnet and a driven magnet located on opposite sides of the mixing chamber. The driving magnet, the driven magnet, and the ferromagnetic stir bar are each capable of rotating about a respective axis. The driving magnet, the driven magnet, and the ferromagnetic stir bar are magnetically coupled such that rotation of the driving magnet induces rotation of the driven magnet and rotation of the driving magnet and the driven magnet induce rotation of the ferromagnetic stir bar. In some embodiments, rotation of the ferromagnetic stir bar within the mixing chamber mixes the sample contained within the mixing chamber.
FILED Wednesday, September 12, 2018
APPL NO 16/761005
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 33/452 (20220101) Original (OR) Class

Apparatus for Enzymology or Microbiology;
C12M 27/02 (20130101)
C12M 47/06 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998942 Widener et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) South Dakota Board of Regents (Pierre, South Dakota)
ASSIGNEE(S) South Dakota Board of Regents (Pierre, South Dakota);  GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia)
INVENTOR(S) Christian Widener (Rapid City, South Dakota);  Victor Champagne (Aberdeen Proving Ground, Maryland);  Matthew Trexler (Aberdeen Proving Ground, Maryland);  Dennis Helfritch (Aberdeen Proving Ground, Maryland);  Rob Hrabe (Rapid City, South Dakota)
ABSTRACT Cold spray devices and systems are disclosed. They include a flowpath having an inlet adapted for receiving communication with two or more inputs and an outlet adapted to discharge the two or more inputs. A discharge nozzle may be included in the flowpath of the outlet and a confluence may be included in the flowpath at the inlet for combining the two or more inputs. A nozzle body houses the discharge nozzle separate and downstream from the confluence of the two inputs.
FILED Wednesday, March 02, 2022
APPL NO 17/684921
ART UNIT 3752 — Fluid Handling and Dispensing
CURRENT CPC
Spraying Apparatus; Atomising Apparatus; Nozzles
B05B 7/1486 (20130101)
B05B 7/1613 (20130101)
B05B 7/1693 (20130101) Original (OR) Class

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 24/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998958 Dhau et al.
FUNDED BY
Department of Defense (DOD)
Strategic Environmental Research and Development Program (SERDP)
APPLICANT(S) Molekule, Inc. (San Francisco, California)
ASSIGNEE(S) Molekule, Inc. (San Francisco, California)
INVENTOR(S) Jaspreet S. Dhau (San Francisco, California);  Chatura Wickramaratne (San Francisco, California)
ABSTRACT A system for removing a coating from an underlying layer can include a wave-based weakening system configured to weaken the coating by decreasing a coupling force between the coating and the substrate, a coating removal mechanism configured to remove the weakened coating from the underlying layer, and a sensor configured to determine a property associated with the coating. A method for removing a coating from an underlying layer can include generating a weakened coating and removing the weakened coating.
FILED Tuesday, December 10, 2019
APPL NO 17/296902
ART UNIT 1717 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Cleaning in General; Prevention of Fouling in General
B08B 7/04 (20130101)
B08B 7/005 (20130101) Original (OR) Class
B08B 7/026 (20130101)
B08B 7/028 (20130101)
B08B 7/0071 (20130101)
B08B 13/00 (20130101)
B08B 2220/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999055 Pale
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Andrew M. Pale (King George, Virginia)
ASSIGNEE(S) United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Andrew M. Pale (King George, Virginia)
ABSTRACT A gripping device is provided for grasping an object. The device includes a frame, an axial threaded screw, an actuator, an armature, a plurality of links, and a plurality of arms. The frame has proximal and distant ends to hold the screw. The actuator connects to the screw at the proximal end. The armature threads onto the screw. The links radially extend from the armature. Each link terminates in a ball tip. Each arm includes a lever bounded by a proximal hinge and a distal claw. The lever contains a plate to slide therealong. The plate has a socket that receives the ball tip. The hinge pivotably connects to the proximal end of the frame. The actuator turns the screw, thereby translating the armature aft towards the distal end of the frame. The armature carries each link to pull its ball tip aft, thereby causing each arm to radially contract its claw around the object.
FILED Monday, August 09, 2021
APPL NO 17/396856
ART UNIT 3651 — Material and Article Handling
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 15/10 (20130101) Original (OR) Class
B25J 15/022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999146 Hemnani et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) The George Washington University (Washington, District of Columbia)
ASSIGNEE(S) The George Washington University (Washington, District of Columbia)
INVENTOR(S) Rohit Anil Hemnani (Washington, District of Columbia);  Volker J. Sorger (Alexandria, Virginia)
ABSTRACT Precision and chip contamination-free placement of two-dimensional (2D) material and van der Waals (VDW) layered materials accelerates both the study of fundamental properties and novel device functionality. The system transfers 2D materials utilizing a combination of a narrow transfer-stamper and viscoelastic and optically transparent film. Precise placement of individual 2D materials results in vanishing cross-contamination to the substrate. The 2D printer results in an aerial cross-contamination improvement of two to three orders of magnitude relative to state-of-the-art transfer methods from a source of average area sub um{circumflex over ( )}2. The transfer-stamper does not physically harm any micro/nanostructures preexisting on the target substrates receiving the 2D material such as, nanoelectronics, waveguides or micro-ring resonators. Such accurate and substrate-benign transfer method for 2D and VDW layered materials provides rapid device prototyping due to its high time-reduction, accuracy, and contamination-free process.
FILED Monday, February 15, 2021
APPL NO 17/176142
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 37/025 (20130101) Original (OR) Class
B32B 41/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)
B82Y 40/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/762 (20130101)
H01L 29/778 (20130101)
H01L 29/1606 (20130101)
H01L 29/66045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999472 Schuster et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
APPLICANT(S) Lockheed Martin Corporation (Bethesda, Maryland)
ASSIGNEE(S) LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
INVENTOR(S) Daniel George Schuster (Bethlehem, Connecticut);  Evan S. Tobin (Sandy Hook, Connecticut);  David N. Schmaling (Southbury, Connecticut)
ABSTRACT A rotor blade retention assembly includes a central hub, a rotor blade including an upper outer surface, a lower outer surface, a blade hole, and a proximal end coupled to the central hub, a strap member extending along a portion of the rotor blade such that a distal end receiving portion extends into the blade hole, and a retainer assembly disposed within the blade hole and coupled to the strap member. The retainer assembly includes an upper bushing and a lower bushing slidably disposed within the blade hole. The upper bushing includes a counterbored portion. The retainer assembly also includes an outboard blade pin disposed within the distal end receiving portion and includes a blade pin inner cavity.
FILED Wednesday, November 03, 2021
APPL NO 17/518370
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Aeroplanes; Helicopters
B64C 27/10 (20130101)
B64C 27/26 (20130101)
B64C 27/35 (20130101)
B64C 27/48 (20130101) Original (OR) Class
B64C 2027/8236 (20130101)
B64C 2027/8272 (20130101)
B64C 2027/8281 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999650 Thostenson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Office of Polar Programs (OPP)
The Office of Polar Programs Antarctic (ANT)
Department of Transportation (USDOT)
Federal Highway Administration (FHWA)
National Highway Traffic Safety Administration (NHTSA)
APPLICANT(S) UNIVERSITY OF DELAWARE (Newark, Delaware)
ASSIGNEE(S)
INVENTOR(S) Erik Thostenson (Newark, Delaware);  Thomas Schumacher (Portland, Oregon)
ABSTRACT Processes for depositing functionalized nanoparticles upon a non-conductive substrate are disclosed herein. The processes may include the step of aerosolizing one or more particles into suspension within a gas, each of the one or more particles comprising functionalized nanoparticles having an electric charge. The processes may include the step the step of attracting the one or more particles onto a non-conductive substrate by a static electric charge opposite of the electric charge, wherein at least portions of the non-conductive substrate are having the static electric charge. The processes may include the step of depositing the functionalized nanoparticles onto the non-conductive substrate.
FILED Wednesday, November 09, 2022
APPL NO 17/983818
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 25/44 (20130101) Original (OR) Class

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/041 (20170501)
C08K 3/042 (20170501)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/4419 (20130101)
C09D 7/61 (20180101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 13/02 (20130101)
C25D 13/12 (20130101)
C25D 13/22 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/254 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999693 Edinger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California);  The Université de Montréal (Montreal, Canada)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Aimee L. Edinger (Irvine, California);  Stephen Hanessian (Irvine, California)
ABSTRACT Small molecules comprised of azacyclic constrained sphingolipid-like compounds and methods of their synthesis are provided. Formulations and medicaments are also provided that are directed to the treatment of disease, such as, for example, neoplasms, cancers, and other diseases. Therapeutics are also provided containing a therapeutically effective dose of one or more small molecule compounds, present either as pharmaceutically effective salt or in pure form, including, but not limited to, formulations for oral, intravenous, or intramuscular administration.
FILED Thursday, October 13, 2022
APPL NO 18/046471
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/40 (20130101)
A61K 45/06 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Heterocyclic Compounds
C07D 207/06 (20130101)
C07D 207/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999796 Wang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The United States of America,as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Qiong J. Wang (Potomac, Maryland);  Zhiya Yu (Potomac, Maryland);  James C. Yang (Bethesda, Maryland)
ABSTRACT The invention provides a chimeric antigen receptor (CAR) having antigenic specificity for CD70, the CAR comprising: an antigen binding—transmembrane domain comprising a CD27 amino acid sequence lacking all or a portion of the CD27 intracellular T cell signaling domain; a 4-1BB intracellular T cell signaling domain; a CD3ζ intracellular T cell signaling domain; and optionally, a CD28 intracellular T cell signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a mammal and methods of treating or preventing cancer in a mammal are also disclosed.
FILED Friday, June 19, 2020
APPL NO 16/906061
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 14/7051 (20130101)
C07K 14/7153 (20130101)
C07K 14/70517 (20130101)
C07K 14/70521 (20130101)
C07K 14/70578 (20130101)
C07K 16/30 (20130101) Original (OR) Class
C07K 16/2875 (20130101)
C07K 2317/60 (20130101)
C07K 2317/622 (20130101)
C07K 2319/00 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999964 Ma et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) California Institute of Technology (Pasadena, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) Yitong Ma (Pasadena, California);  Mark W. Budde (Pasadena, California);  Michaelle N. Mayalu (Pasadena, California);  Michael B. Elowitz (Pasadena, California)
ABSTRACT Disclosed herein include circuits, compositions, nucleic acids, populations, systems, and methods enabling cells to sense, control, and/or respond to their own population size. In some embodiments, an orthogonal communication channel allows specific communication between engineered cells. Also described herein, in some embodiments, is an evolutionarily robust ‘paradoxical’ regulatory circuit architecture in which orthogonal signals both stimulate and inhibit net cell growth at different signal concentrations. In some embodiments, engineered cells autonomously reach designed densities and/or activate therapeutic or safety programs at specific density thresholds. Methods of treatment are also provided in some embodiments.
FILED Friday, August 27, 2021
APPL NO 17/460120
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/415 (20130101)
C07K 2319/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0069 (20130101)
C12N 9/86 (20130101)
C12N 15/11 (20130101)
C12N 15/85 (20130101) Original (OR) Class
C12N 2310/20 (20170501)
C12N 2800/107 (20130101)
C12N 2810/10 (20130101)

Enzymes
C12Y 113/12003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000004 Shen-Gunther
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
APPLICANT(S) The Government of The United States, as represented by The Secretary of The Army (Fort Detrick, Maryland)
ASSIGNEE(S) The Government of The United States, as represented by The Secretary of The Army (, None)
INVENTOR(S) Jane Shen-Gunther (San Antonio, Texas)
ABSTRACT Disclosed herein are methods for molecularly characterizing cervical cell samples as being negative for intraepithelial lesion or malignancy (NILM), low-grade squamous intraepithelial lesion (LSIL), or high-grade squamous intraepithelial lesion (HSIL).
FILED Tuesday, June 14, 2022
APPL NO 17/839803
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/686 (20130101)
C12Q 1/708 (20130101)
C12Q 1/6851 (20130101)
C12Q 1/6883 (20130101)
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/112 (20130101)
C12Q 2600/154 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000062 Claflin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Bruce B. Claflin (Dayton, Ohio);  Gordon J. Grzybowski (Kettering, Ohio);  Arnold M. Kiefer (Dayton, Ohio)
ABSTRACT A method for depositing a monocrystalline or polycrystalline tin alloy layer on an amorphous or crystallographically mis-matched substrate. The method includes selecting tin halide as the tin source; selecting an alloying metal precursor from germanium precursors, silicon precursors, and mixtures of germanium and silicon precursors; selecting a substrate from amorphous substrates and crystallographically mis-matched substrates; generating an inert gas plasma in a remote plasma generation reactor; contacting the inert gas plasma with the tin halide to provide an activated tin halide flow stream; contacting the inert gas plasma with the alloying metal precursor to provide an activated alloying metal flow stream; directing the activated tin halide flow stream and activated alloying metal flow stream to an alloy deposition chamber physically remote from the plasma chamber; and depositing the monocrystalline or polycrystalline tin alloy layer on the substrate in the deposition chamber.
FILED Tuesday, July 30, 2019
APPL NO 16/526015
ART UNIT 1713 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/06 (20130101)
C23C 16/50 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 25/105 (20130101) Original (OR) Class
C30B 25/165 (20130101)
C30B 29/52 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0262 (20130101)
H01L 21/02535 (20130101)
H01L 21/02595 (20130101)
H01L 21/02598 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000437 Black
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Rolls-Royce Corporation (Indianapolis, Indiana)
ASSIGNEE(S) Rolls-Royce Corporation (Indianapolis, Indiana)
INVENTOR(S) Joseph D. Black (Indianapolis, Indiana)
ABSTRACT In one example, a cone clutch assembly including an inner cone member rotationally coupled to a first shaft, the inner cone member defining a first friction surface; an outer cone member rotationally coupled to a second shaft, the outer cone member defining a second friction surface opposing the first friction surface; and an independent friction member positioned between the inner and the outer cone member. The inner cone member and outer cone member are configured to be selectively engaged and disengaged from each other. When the inner cone member is engaged with the outer cone member, the first friction surface of the inner cone member frictionally engages one surface of the friction member, and the second friction surface of the outer cone member engages another surface of the friction member such that rotational motion is transferred between the inner and outer cone member via the friction member.
FILED Tuesday, June 27, 2023
APPL NO 18/342498
ART UNIT 3659 — Material and Article Handling
CURRENT CPC
Couplings for Transmitting Rotation; Clutches; Brakes
F16D 13/26 (20130101)
F16D 13/66 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000698 Gilbert et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Noah Gilbert (Waltham, Massachusetts);  Joshua Brown (Newton, Massachusetts)
ABSTRACT A polarization-separated, phase-shifted interferometer can generate interferograms without moving parts. It uses a phase shifter, such as an electro-optic phase modulator, to modulate the relative phase between sample and reference beams. These beams are transformed into orthogonal polarization states (e.g., horizontally and vertically polarized states) and coupled via a common path (e.g., polarization-maintaining fiber) to a polarizing beam splitter (PBS), which sends them into separate sample and reference arms. Quarter-wave plates in the sample and reference arms rotate the polarization states of the sample and reference beams so they are coupled out of the PBS to a detector via a 45° linear polarizer. The polarizer projects the aligned polarization components of the sample and reference beams onto the detector, where they interfere with known relative phase to produce an output that can be used to map surface topography of the test object.
FILED Monday, January 10, 2022
APPL NO 17/572353
ART UNIT 2877 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 9/0201 (20130101) Original (OR) Class
G01B 9/02051 (20130101)
G01B 9/02067 (20130101)
G01B 11/2441 (20130101)
G01B 2290/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000878 Chini et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Michael Chini (Orlando, Florida);  Yangyang Liu (Orlando, Florida);  Shima Gholam-Mirzaei (Orlando, Florida);  John Beetar (Orlando, Florida);  Jonathan Nesper (Orlando, Florida)
ABSTRACT A laser diagnostic device may include a beamsplitter to split one or more input pulses into one or more fundamental pulses and one or more perturbing pulses, one or more beam-combining optics to combine the fundamental and perturbing pulses at a detection plane, a detector including a solid-state material at the detection plane, and a controller. The controller may receive a detector signal from the detector is indicative of nonlinear absorption in the solid-state medium of the fundamental pulses that is perturbed by the perturbing pulses. The controller may further extract a temporal electric field waveform of the one or more input pulses from the detector signal and provide as an output at least one of the temporal electric field waveform, a spectrum, or a spectral phase of the one or more input pulses.
FILED Monday, March 07, 2022
APPL NO 17/688637
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/443 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 29/12 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 27/108 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3551 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000949 Ravenscroft et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) University of Kansas (Lawrence, Kansas);  THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia)
ASSIGNEE(S) University of Kansas (Lawrence, Kansas);  The United States of America as Represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Gerald Brandon Ravenscroft (Overland Park, Kansas);  Patrick M. McCormick (Berryton, Kansas);  Shannon D. Blunt (Shawnee, Kansas);  Erik S. Perrins (Lawrence, Kansas);  Justin G. Metcalf (Dayton, Ohio)
ABSTRACT Systems, methods, and computer-readable storage media for generating, transmitting, and utilizing a composite radar and communication waveform are disclosed. The composite radar and communication waveform may facilitate radar detection and data communication operations and may be generated from a frequency modulated (FM) radar waveform and a communication signal. In an aspect, the composite radar and communication waveform may be generated by iteratively executing a shaping process against the FM radar waveform and the communication signal until a first stop criterion is satisfied to produce an initial composite radar and communication waveform having the communication signal embedded therein, and then iteratively executing an enhancement process against the initial composite radar waveform and the communication signal until a second stop criterion is satisfied to produce a final composite radar and communication waveform suitable for both radar detection and data communication operations.
FILED Saturday, September 21, 2019
APPL NO 17/269077
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/006 (20130101) Original (OR) Class
G01S 13/347 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/2626 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12001069 Wood et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S) AirBorn Inc. (Georgetown, Texas)
ASSIGNEE(S) AirBorn, Inc. (Georgetown, Texas)
INVENTOR(S) Lance A. Wood (Winter Park, Colorado);  Harsha Krishna Kopuru (Parker, Colorado);  Rebekah Jean Mitchell (Littleton, Colorado);  Jason Paul Smith (Sartell, Minnesota);  Timothy John Wasland (Little Falls, Minnesota)
ABSTRACT A space active optical cable (SAOC) includes a cable including one or more optical fibers, and two or more electrical transceivers on opposing ends of the cable and interconnected by the cable. Each of the electrical transceivers includes an enclosure that encloses one or more light sources, one or more light detectors, and control electronics. Also included in the enclosure are a coupling medium to couple light into and out of the one or more optical fibers. The coupling medium can be reflecting surface or an on-axis mount. The enclosure provides a suitable heat propagation and electromagnetic interference (EMI) shielding, and the cable and the two or more electrical transceivers are radiation resistant. SAOC features optionally support a health check algorithm that allows trending optical performance in the absence of an optical connector and a potential surface treatment to increase nominally low emissivity of an EMI conductive surface.
FILED Tuesday, July 25, 2023
APPL NO 18/225902
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/428 (20130101)
G02B 6/4206 (20130101)
G02B 6/4214 (20130101)
G02B 6/4246 (20130101) Original (OR) Class
G02B 6/4267 (20130101)
G02B 6/4277 (20130101)
G02B 6/4284 (20130101)
G02B 6/4286 (20130101)
G02B 6/4415 (20130101)

Transmission
H04B 10/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12001841 Martínez et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) José F. Martínez (Ithaca, New York);  Helena Caminal (Ithaca, New York);  Kailin Yang (Ithaca, New York);  Khalid Al-Hawaj (Ithaca, New York);  Christopher Batten (Ithaca, New York)
ABSTRACT A content-addressable processing engine, also referred to herein as CAPE, is provided. Processing-in-memory (PIM) architectures attempt to overcome the von Neumann bottleneck by combining computation and storage logic into a single component. CAPE provides a general-purpose PIM microarchitecture that provides acceleration of vector operations while being programmable with standard reduced instruction set computing (RISC) instructions, such as RISC-V instructions with standard vector extensions. CAPE can be implemented as a standalone core that specializes in associative computing, and that can be integrated in a tiled multicore chip alongside other types of compute engines. Certain embodiments of CAPE achieve average speedups of 14× (up to 254×) over an area-equivalent out-of-order processor core tile with three levels of caches across a diverse set of representative applications.
FILED Thursday, September 22, 2022
APPL NO 17/950560
ART UNIT 2183 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 9/3001 (20130101)
G06F 9/3004 (20130101)
G06F 9/30036 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12001867 Shen et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Zhiming Shen (Ithaca, New York);  Robbert van Renesse (Ithaca, New York);  Hakim Weatherspoon (Ithaca, New York)
ABSTRACT A method in one embodiment comprises implementing a kernel-based isolation layer, configuring a software container on the kernel-based isolation layer to include a dedicated operating system kernel as a library operating system, and executing one or more user processes in the software container. The method is performed by a cloud-based processing platform, an enterprise processing platform, or other type of processing platform comprising a plurality of processing devices, with each such processing device comprising a processor coupled to a memory. The library operating system illustratively runs in the software container at a privilege level that is the same as a privilege level of the one or more user processes executing in the software container. The library operating system is illustratively configured to support automatic translation of binaries of the one or more user processes in conjunction with converting system calls into corresponding function calls.
FILED Thursday, April 11, 2019
APPL NO 17/046632
ART UNIT 2196 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/545 (20130101)
G06F 9/4555 (20130101)
G06F 9/45558 (20130101) Original (OR) Class
G06F 2009/45587 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12001905 Fink et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
U.S. Army Picatinny Arsenal (PICA)
APPLICANT(S) Advanced Functional Fabrics of America (Cambridge, Massachusetts)
ASSIGNEE(S) Advanced Functional Fabrics of America (Cambridge, Massachusetts)
INVENTOR(S) Yoel Fink (Brookline, Massachusetts);  Nicholas Dimitruk (Belmont, Massachusetts);  Federico Bescotti (Boston, Massachusetts);  Catherine Chapman (Spartanburg, South Carolina)
ABSTRACT Exemplary embodiments use a single, physical embodiment that compiles independent machine-readable codes together with little to no space in between codes. This physical embodiment is in two primary forms—adhesive tape or fabric strips with hook and loop backing. A code reader device, with software compatible with the machine-readable codes, can rapidly or simultaneously aggregate independent codes together on the physical embodiment in order to assign them to one or more digital addresses.
FILED Monday, April 24, 2023
APPL NO 18/138381
ART UNIT 2876 — Optics
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 19/06037 (20130101)
G06K 19/06093 (20130101) Original (OR) Class

Displaying; Advertising; Signs; Labels or Name-plates; Seals
G09F 3/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12001934 Olson et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Edwin Olson (Ann Arbor, Michigan);  Dhanvin H. Mehta (Ann Arbor, Michigan);  Gonzalo Ferrer (Ann Arbor, Michigan)
ABSTRACT In Multi-Policy Decision-Making (MPDM), many computationally-expensive forward simulations are performed in order to predict the performance of a set of candidate policies. In risk-aware formulations of MPDM, only the worst outcomes affect the decision making process, and efficiently finding these influential outcomes becomes the core challenge. Recently, stochastic gradient optimization algorithms, using a heuristic function, were shown to be significantly superior to random sampling. In this disclosure, it was shown that accurate gradients can be computed—even through a complex forward simulation—using approaches similar to those in dep networks. The proposed approach finds influential outcomes more reliably, and is faster than earlier methods, allowing one to evaluate more policies while simultaneously eliminating the need to design an easily-differentiable heuristic function.
FILED Friday, May 12, 2023
APPL NO 18/196897
ART UNIT 2692 — Selective Visual Display Systems
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 3/02 (20130101) Original (OR) Class
G06N 3/008 (20130101)
G06N 3/084 (20130101)
G06N 7/01 (20230101)

Pictorial Communication, e.g Television
H04N 1/00002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12002150 Zhao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
Office of Naval Research (ONR)
Non-Profit Organization (NPO)
Semiconductor Research Corporation (SRC)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Yajie Zhao (Los Angeles, California);  Jing Yang (Los Angeles, California);  Hanyuan Xiao (Los Angeles, California)
ABSTRACT Methods and systems are provided for rendering photo-realistic images of a subject or an object using a differentiable neural network for predicting indirect light behavior. In one example, the differentiable neural network outputs a volumetric light map comprising a plurality of spherical harmonic representations. Further, using a reflectance neural network, roughness and scattering coefficients associated with the subject or the object is computed. The volumetric light map, as well as the roughness and scattering coefficients are the utilized for rendering a final image under one or more of a desired lighting condition, desired camera view angle, and/or with a desired visual effect (e.g., expression change).
FILED Tuesday, May 03, 2022
APPL NO 17/735869
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Image Data Processing or Generation, in General
G06T 15/04 (20130101)
G06T 15/10 (20130101)
G06T 15/80 (20130101)
G06T 15/506 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12002605 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Yuepeng Zhang (Naperville, Illinois);  John N. Hryn (Hawthorn Woods, Illinois);  Yunsong Xie (Austin, Texas)
ABSTRACT Magnetic nanowire components may be used in passive radio-frequency device allowing for smaller size devices, lower power consumption, and on-chip packaging potential across a wide range of technologies. A method for fabricating magnetic nanowire component electronic devices include depositing a conductive device pattern and transmission lines onto a substrate, aligning and securing a magnetic nanowire component to the device pattern, packaging the device with an insulation layer. Alternatively, the conductive device pattern and transmission lines may be deposited on the magnetic nanowire component, and the magnetic nanowire component may then be attached to a substrate.
FILED Tuesday, February 16, 2021
APPL NO 17/176506
ART UNIT 2896 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 25/00 (20130101)
B82Y 40/00 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 1/006 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/0081 (20130101) Original (OR) Class
H01F 1/143 (20130101)
H01F 41/30 (20130101)
H01F 41/0253 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12002888 Lu
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) XEROX CORPORATION (Norwalk, Connecticut)
ASSIGNEE(S) XEROX CORPORATION (Norwalk, Connecticut)
INVENTOR(S) Jengping Lu (Fremont, California)
ABSTRACT A device includes a first transistor having a first source, a first gate, a first drain, and one or more electrodes. The first transistor serves as an inverter. The device also includes a second transistor having a second source, a second gate, and a second drain. The first and second sources are connected together. The first and second drains are connected together. The second transistor serves as an output, a driver, or both. The one or more electrodes, the second gate, or a combination thereof serve as tapped drains that are configured to sample a stepped voltage of the second transistor.
FILED Tuesday, March 09, 2021
APPL NO 17/196354
ART UNIT 2871 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/13306 (20130101)
G02F 1/13452 (20130101)
G02F 1/13454 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 27/1251 (20130101)
H01L 29/404 (20130101)
H01L 29/78669 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12002891 Usenko et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Alex Usenko (Lake St. Louis, Missouri);  Anthony Caruso (Overland Park, Kansas);  Steven Bellinger (Manhattan, Kansas)
ASSIGNEE(S) THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri)
INVENTOR(S) Alex Usenko (Lake St. Louis, Missouri);  Anthony Caruso (Overland Park, Kansas);  Steven Bellinger (Manhattan, Kansas)
ABSTRACT A method of producing a four-layer silicon diode, including selecting a first silicon wafer, wherein said first silicon wafer is CZ-grown B-doped with <100> orientation, a resistivity of less than 0.01 Ohm-cm, and an oxygen content of greater than 10 ppma, and then selecting a second silicon wafer, wherein said second silicon wafer is CZ-grown P-doped with <100> orientation, a resistivity of less than 0.005 Ohm-cm, and an oxygen content of greater than 10 ppma, followed by cleaning the respective first and second silicon wafers. The wafers are then HF treated to yield respective first and second cleaned wafers, the first cleaned wafer is positioned into a first furnace and the second cleaned wafer is positioned into a second furnace, wherein the first and second furnaces are not unitary. Next is annealing the respective first and second cleaned wafers in a reducing atmosphere to yield respective first and second respective out-diffused gradient wafers, followed by bonding together respective first and second heat-treated wafers to yield a mated and/or bonded four-layer substrate having a first heavy doped n-type layer, a second gradient doped n-type layer, a third gradient doped p-type layer, and a fourth heavy doped p-type layer.
FILED Thursday, June 30, 2022
APPL NO 17/855735
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/861 (20130101) Original (OR) Class
H01L 29/66121 (20130101)
H01L 29/66136 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12002973 Skalny et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia)
ASSIGNEE(S) GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY (Washington, District of Columbia)
INVENTOR(S) David Anthony Skalny (Shelby Township, Michigan);  Craig William Schmehl (Royal Oak, Michigan)
ABSTRACT A surrogate component for a test system is described that includes a body having a first shell, a second shell coupled to the first shell, and a wiring harness. The first shell includes a plurality of exit holes and the second shell includes a first connection interface and a second connection interface. The wiring harness passes through at least one of the plurality of exit holes of the first shell and includes at least one data communication line coupled to the first connection interface and at least one power line coupled to the second connection interface.
FILED Wednesday, December 02, 2020
APPL NO 17/109432
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/425 (20130101)
H01M 50/20 (20210101)
H01M 50/172 (20210101) Original (OR) Class
H01M 2220/20 (20130101)

Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 13/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12003114 Sun et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia)
ASSIGNEE(S) VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia)
INVENTOR(S) Keyao Sun (Blacksburg, Virginia);  Jun Wang (Blacksburg, Virginia);  Rolando Burgos (Blacksburg, Virginia);  Dushan Boroyevich (Blacksburg, Virginia)
ABSTRACT Aspects of an efficient compensation network for reducing reactive power in a wireless power transfer (WPT) system are disclosed. The compensation network comprises a series/series (S/S) constant current (CC) source, a reactive power compensation capacitor, and a constant current (CC)-to-constant voltage (CV) network. In an example, the S/S CC source comprises a first capacitor connected in series with a first inductor on a primary side of a transformer and a second inductor on a secondary side of the transformer. The S/S CC source converts an input voltage signal of the WPT system into a constant alternating current (AC) current signal. In an example, the CC-to-CV network comprises at least a third capacitor and a third inductor. The CC-to-CV network converts the constant AC current signal into a constant AC voltage signal.
FILED Friday, June 26, 2020
APPL NO 16/913066
ART UNIT 2839 — Semiconductors/Memory
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/12 (20160201) Original (OR) Class

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 7/5387 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 11998602 Lairson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute on Drug Abuse (NIDA)
National Institute of General Medical Sciences (NIGMS)
NIH Office of the Director (NIHOD)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Scripps Research Institute (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Luke Lairson (San Diego, California);  Brittney Beyer (San Diego, California);  Mingliang Fang (Singapore, Singapore);  Gary Siuzdak (Cardiff, California)
ABSTRACT This invention provides novel methods for treating or ameliorating symptoms of demyelinating diseases such as multiple sclerosis. The methods involve administering to subjects in need of treatment a pharmaceutical composition that contains a therapeutically effective amount of taurine and also a compound that induces oligodendrocyte precursor cell (OPC) differentiation (e.g., T3, benztropine, clemastine or miconazole). Some of the methods additionally involve administration to the subject a known agent for treating demyelinating diseases (e.g., SIP receptor agonists) or a known disease modifying drug. The invention also provides methods for increasing myelination and methods for promoting OPC differentiation into oligodendrocytes. These methods entail contacting a population of OPCs with a combination of taurine and a known OPC differentiation-inducing agent such as T3, clemastine, benztropine or miconazole.
FILED Tuesday, November 13, 2018
APPL NO 16/978558
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 303/02 (20130101)

Peptides
C07K 16/286 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999011 Moorehead et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Michael Joseph Moorehead (Middleton, Wisconsin);  Adrien Couet (Madison, Wisconsin);  Dan J. Thoma (Madison, Wisconsin)
ABSTRACT As may be implemented in accordance with one or more approaches herein, a plurality of metal alloy samples are formed on a surface, in which each sample has a different metal alloy composition relative to the others. Elemental metal powders are provided from hoppers at respective delivery rates and mixed, such that the mixture for each sample is set via the respective delivery rates and is different than the mixture for the other samples. Multiple layers of each mixture are deposited by dispensing and melting the mixture to form the respective samples, and one or more layer of each of the samples is remelted
FILED Friday, October 04, 2019
APPL NO 16/593431
ART UNIT 3761 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/147 (20130101)
B23K 26/342 (20151001) Original (OR) Class
B23K 26/1464 (20130101)
B23K 2103/18 (20180801)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)

Alloys
C22C 1/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999106 DeMuth et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) James A. DeMuth (Mountain View, California);  Eric B. Duoss (Danville, California);  Joshua D. Kuntz (Livermore, California);  Paul A. Rosso (Livermore, California);  Christopher M. Spadaccini (Oakland, California)
ABSTRACT The present disclosure relates to a system and apparatus having an optic and a cooling system for cooling the optic. In one example an optically addressed light valve forms the optic. The cooling system includes first and second windows on opposing surfaces of the optically addressed light valve which constrain a cooling fluid to flow over the opposing surfaces. The fluid pressure outside the optically addressed light valve is low enough that it does not compress a liquid crystal gap of the optically addressed light valve. The cooling fluid is also transparent to a high powered light beam which is projected through the first and second windows, and also through the optically addressed light valve, during an additive manufacturing operation.
FILED Thursday, July 16, 2020
APPL NO 16/931122
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/10 (20210101)
B22F 10/28 (20210101)
B22F 12/20 (20210101)
B22F 12/41 (20210101)

Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam
B23K 26/703 (20151001)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/268 (20170801) Original (OR) Class

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 30/00 (20141201)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/0126 (20130101)
G02F 1/132 (20130101)
G02F 1/135 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 3/0407 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 10/25 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999284 Campbell et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Terabase Energy, Inc. (Berkeley, California)
ASSIGNEE(S) Terabase Energy, Inc. (Berkeley, California)
INVENTOR(S) Matthew Campbell (Berkeley, California);  Brian Coleman (Portland, Oregon);  Tianya Zhao (Pacifica, California);  Adam Hansel (Davis, California);  Soren Jensen (Corte Madera, California)
ABSTRACT A solar table mobile transport is described that moves a solar table to a point of installation. The solar table mobile transport comprises multiple motors that allow movement within a three-dimensional coordinate system as well as provide angular controls of pitch, yaw and roll. These motors enable at least one alignment process used to install the solar table to a mounting structure within a solar system.
FILED Wednesday, September 01, 2021
APPL NO 17/464178
ART UNIT 3612 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Vehicles Adapted for Load Transportation or to Transport, to Carry, or to Comprise Special Loads or Objects
B60P 3/00 (20130101) Original (OR) Class

Solar Heat Collectors; Solar Heat Systems
F24S 25/30 (20180501)
F24S 25/65 (20180501)

Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules
H02S 99/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999628 O'Hara et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) BATTELLE MEMORIAL INSTITUTE (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Matthew J. O'Hara (Richland, Washington);  Gabriel B. Hall (Richland, Washington);  Lucas P. Boron-Brenner (Richland, Washington)
ABSTRACT Systems and/or methods for producing free elements, systems and/or methods for producing element storage/generation vessel assemblies, element storage/generation vessel assemblies, system and/or methods for purifying elements and providing a progeny generating assemblies are provided.
FILED Friday, December 11, 2020
APPL NO 17/120084
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 15/10 (20130101)

Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 2101/57 (20220101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/20 (20130101)
B01J 20/34 (20130101)

Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals
C01F 13/00 (20130101) Original (OR) Class

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/683 (20130101)

Conversion of Chemical Elements; Radioactive Sources
G21G 1/001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999630 Libera et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois)
INVENTOR(S) Joseph A. Libera (Clarendon Hills, Illinois);  Yujia Liang (Lisle, Illinois);  Trevor L. Dzwiniel (Carol Stream, Illinois);  Krzysztof Pupek (Plainfield, Illinois);  Gregory K. Krumdick (Homer Glen, Illinois);  Stephen Cotty (Lemont, Illinois)
ABSTRACT A process for forming cubic LLZO through the use of atomic mixing of metal salts used in an aerosol process. The cubic LLZO is formed at temperatures below 1000° C.
FILED Monday, June 15, 2020
APPL NO 16/901998
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 2/06 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 25/006 (20130101) Original (OR) Class

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/54 (20130101)
C01P 2002/72 (20130101)
C01P 2002/76 (20130101)
C01P 2004/02 (20130101)
C01P 2004/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999805 Harmon et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Brooke Nicole Harmon (Livermore, California);  Yooli Kim Light (Pleasanton, California);  Mary Bao Tran-Gyamfi (Pleasanton, California);  Joseph S. Schoeniger (Oakland, California);  Edwin A. Saada (Dublin, California);  Kenneth L. Sale (Pleasanton, California)
ABSTRACT Specific and broad-spectrum inhibitory peptides to CRISPR Cas9 variants (SpyCas9, SauCas9, and CjeCas9) are disclosed. A method of making and using these peptides with therapeutic CRISPR Cas9 (to improve desired targeting) or against harmful CRISPR Cas9 components (already active in a patient) is also disclosed. The peptides combined with a delivery system is also disclosed.
FILED Wednesday, May 06, 2020
APPL NO 16/867698
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0053 (20130101)
A61K 38/465 (20130101)

Peptides
C07K 7/08 (20130101) Original (OR) Class
C07K 14/001 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2310/20 (20170501)
C12N 2310/3513 (20130101)
C12N 2310/3519 (20130101)

Enzymes
C12Y 301/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999836 Smalyukh et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S)
INVENTOR(S) Ivan I. Smalyukh (Boulder, Colorado);  Andrew Johnston Hess (Louisville, Colorado);  Quingkun Liu (Boulder, Colorado);  Joshua A. De La Cruz (Denver, Colorado);  Blaise Fleury (Boulder, Colorado);  Eldho Abraham (Boulder, Colorado);  Bohdan Senyuk (Boulder, Colorado);  Vladyslav Cherpak (Westminster, Colorado)
ABSTRACT Disclosed are cellulose-based 5 flexible aerogels and xerogels containing bacterial cellulose nanorods, ribbons, fibers, and the like, wherein the gels have tunable optical, heat transfer, and stiffness properties. Further disclosed are highly transparent and flexible cellulose nanofiber-polysiloxane composite aerogels featuring enhanced mechanical robustness, tunable optical anisotropy, and low thermal conductivity.
FILED Thursday, June 13, 2019
APPL NO 17/251694
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/18 (20130101)
C08J 9/28 (20130101) Original (OR) Class
C08J 2201/026 (20130101)
C08J 2201/0504 (20130101)
C08J 2205/026 (20130101)
C08J 2205/028 (20130101)
C08J 2301/02 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/544 (20130101)
C08K 7/02 (20130101)
C08K 2201/011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000334 Sobanski et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Raytheon Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RTX CORPORATION (Farmington, Connecticut)
INVENTOR(S) Jon E. Sobanski (Glastonbury, Connecticut);  Jesse M. Chandler (S. Windsor, Connecticut)
ABSTRACT A turbine engine is provided that includes a fan section, a turbine engine core and a recovery system. The turbine engine core is configured to power the fan section. The turbine engine core includes a core compressor section, a core combustor section and a core turbine section. A centerline axis of the turbine engine core is offset from a centerline axis of the turbine engine. The recovery system includes an evaporator module and a condenser module. A core flowpath extends sequentially through the core compressor section, the core combustor section, the core turbine section, the evaporator module and the condenser module from an inlet into the core flowpath to an exhaust from the core flowpath.
FILED Wednesday, March 08, 2023
APPL NO 18/119169
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants
F02C 3/30 (20130101) Original (OR) Class
F02C 7/12 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
F05D 2260/213 (20130101)
F05D 2270/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000662 Erno et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Daniel Jason Erno (Clifton Park, New York);  William Dwight Gerstler (Niskayuna, New York);  Biao Fang (Clifton Park, New York);  Laura Cerully Dial (Clifton Park, New York);  Voramon Supatarawanich Dheeradhada (Latham, New York);  Hendrik Pieter Jacobus de Bock (Clifton Park, New York)
ABSTRACT A thermal structure for management of thermal energy, the thermal structure including: a first wall structure defining a first cavity; a second wall structure defining a second cavity, the second cavity in fluid communication with the first cavity; and a barrier cavity defined at least in-part by the first wall structure and the second wall structure, wherein the barrier cavity is disposed between the first cavity and the second cavity and includes a pressurized barrier fluid therein or is configured to receive the pressurized barrier fluid during operation of the thermal structure.
FILED Tuesday, October 05, 2021
APPL NO 17/494410
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 9/0018 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000732 Williams
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Brian P. Williams (Oak Ridge, Tennessee)
ABSTRACT A system and method with AC coupling that reserves photodiode bandwidth in a biased configuration, allows optimal transimpedance amplifier performance, retains DC signal measurement capability, and does not introduce noise into the balanced detection signal.
FILED Monday, January 23, 2023
APPL NO 18/100147
ART UNIT 2878 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 1/18 (20130101) Original (OR) Class
G01J 1/4228 (20130101)
G01J 2001/186 (20130101)
G01J 2001/444 (20130101)
G01J 2001/446 (20130101)

Electric Digital Data Processing
G06F 7/588 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 47/11 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000776 Mallery et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) REBELLION PHOTONICS, INC. (Houston, Texas)
ASSIGNEE(S) REBELLION PHOTONICS, INC. (Houston, Texas)
INVENTOR(S) Ryan Mallery (Houston, Texas);  Ohad Israel Balila (Friendswood, Texas);  Robert Timothy Kester (Friendswood, Texas)
ABSTRACT An infrared (IR) imaging system for determining a concentration of a target species in an object is disclosed. The imaging system can include an optical system including a focal plane array (FPA) unit behind an optical window. The optical system can have components defining at least two optical channels thereof, said at least two optical channels being spatially and spectrally different from one another. Each of the at least two optical channels can be positioned to transfer IR radiation incident on the optical system towards the optical FPA. The system can include a processing unit containing a processor that can be configured to acquire multispectral optical data representing said target species from the IR radiation received at the optical FPA. One or more of the optical channels may be used in detecting objects on or near the optical window, to avoid false detections of said target species.
FILED Tuesday, March 07, 2023
APPL NO 18/179879
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/0806 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/314 (20130101)
G01N 21/3504 (20130101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 5/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000802 Asif et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Bruker Nano, Inc. (Santa Barbara, California)
ASSIGNEE(S) Bruker Nano, Inc. (Santa Barbara, California)
INVENTOR(S) Syed Amanulla Syed Asif (Bloomington, Minnesota);  Edward Cyrankowski (Woodbury, Minnesota);  Bartosz Nowakowski (Plymouth, Minnesota);  Douglas D. Stauffer (Minneapolis, Minnesota)
ABSTRACT Among other things, a heating jacket configured for heating a mechanical testing instrument having a probe is disclosed herein. The heating jacket includes a heating element including a jacket wall, and the jacket wall extends around a probe recess, the jacket wall is configured to receive a probe of a mechanical testing instrument within the probe recess, and the heating element is mechanically isolated from the probe with a probe gap. Additionally, a system to correct for thermomechanical drift in a mechanical testing assembly is disclosed herein. The system isolates the mechanical testing instrument from thermomechanical drift of a system frame using a determined difference between, for instance, a probe displacement and a sample displacement.
FILED Tuesday, November 13, 2018
APPL NO 16/763319
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 3/062 (20130101) Original (OR) Class
G01N 3/068 (20130101)
G01N 2203/0226 (20130101)
G01N 2291/02845 (20130101)
G01N 2291/02872 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000878 Chini et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Michael Chini (Orlando, Florida);  Yangyang Liu (Orlando, Florida);  Shima Gholam-Mirzaei (Orlando, Florida);  John Beetar (Orlando, Florida);  Jonathan Nesper (Orlando, Florida)
ABSTRACT A laser diagnostic device may include a beamsplitter to split one or more input pulses into one or more fundamental pulses and one or more perturbing pulses, one or more beam-combining optics to combine the fundamental and perturbing pulses at a detection plane, a detector including a solid-state material at the detection plane, and a controller. The controller may receive a detector signal from the detector is indicative of nonlinear absorption in the solid-state medium of the fundamental pulses that is perturbed by the perturbing pulses. The controller may further extract a temporal electric field waveform of the one or more input pulses from the detector signal and provide as an output at least one of the temporal electric field waveform, a spectrum, or a spectral phase of the one or more input pulses.
FILED Monday, March 07, 2022
APPL NO 17/688637
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/443 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 29/12 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 27/108 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3551 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12001058 Namazi et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Qunnect, Inc. (Brooklyn, New York)
ASSIGNEE(S) Qunnect, Inc. (Brooklyn, New York)
INVENTOR(S) Mehdi Namazi (Brooklyn, New York);  Mael Flament (Brooklyn, New York);  Yang Wang (New York, New York);  Alexander Craddock (Brooklyn, New York)
ABSTRACT A quantum memory device and methods for storage and retrieval of a qubit from the quantum memory device are described. The quantum memory device includes a first optical component to convert an input qubit encoded in an arbitrary polarization state of a photon into a spatial qubit propagating in a pair of parallel optical rails, an atomic vapor memory to store the spatial qubit in an atomic vapor, and a second optical component to combine the spatial qubit, when retrieved from the atomic vapor memory, into an output qubit encoded in an arbitrary polarization state of a photon.
FILED Friday, February 04, 2022
APPL NO 18/275567
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/2931 (20130101)
G02B 6/29358 (20130101) Original (OR) Class
G02B 27/283 (20130101)
G02B 27/286 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12001228 Kishore et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado)
INVENTOR(S) Ravi Anant Kishore (Lakewood, Colorado);  Sampath Kommandur (Golden, Colorado);  Charles William Booten (Arvada, Colorado);  Lance Michael Wheeler (Wheat Ridge, Colorado);  Shuang Cui (Dallas, Texas)
ABSTRACT The present disclosure relates to a directional heat transfer using thermal control devices, including a dual phase change thermal diode and an active contact-based thermal switch. The thermal diode includes a positive temperature coefficient switching material and a negative temperature coefficient switching material arranged in series. The thermal switch includes two thermally conducting surfaces which may be moved to contact (i.e., having a distance between them of substantially zero) creating minimal thermal contact resistance. Both thermal control devices may be used to control heat flow into and/or out of a building.
FILED Thursday, April 07, 2022
APPL NO 17/715144
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Systems for Controlling or Regulating Non-electric Variables
G05D 23/121 (20130101) Original (OR) Class

Electric Switches; Relays; Selectors; Emergency Protective Devices
H01H 37/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12001237 Tomei et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Matthew Tomei (Champaign, Illinois);  Shomit N. Das (Austin, Texas);  David A. Wood (Austin, Texas)
ABSTRACT Systems, methods, and devices for performing pattern-based cache block compression and decompression. An uncompressed cache block is input to the compressor. Byte values are identified within the uncompressed cache block. A cache block pattern is searched for in a set of cache block patterns based on the byte values. A compressed cache block is output based on the byte values and the cache block pattern. A compressed cache block is input to the decompressor. A cache block pattern is identified based on metadata of the cache block. The cache block pattern is applied to a byte dictionary of the cache block. An uncompressed cache block is output based on the cache block pattern and the byte dictionary. A subset of cache block patterns is determined from a training cache trace based on a set of compressed sizes and a target number of patterns for each size.
FILED Wednesday, September 23, 2020
APPL NO 17/029158
ART UNIT 2133 — Memory Access and Control
CURRENT CPC
Electric Digital Data Processing
G06F 3/0608 (20130101) Original (OR) Class
G06F 3/0655 (20130101)
G06F 3/0676 (20130101)
G06F 3/0679 (20130101)
G06F 12/0802 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12002595 Abergel et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Basic Energy Sciences (BES)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Rebecca J. Abergel (Oakland, California);  Gauthier J. P. Deblonde (Oakland, California);  Abel Ricano (Oakland, California)
ABSTRACT Provided herein are separation processes for metal ions present in aqueous solutions based on methods involving liquid-liquid extraction. The separation process involves a chelator that can selectively bind to at least one of the metals at a relatively low pH. This can be used, for example, for recovery and purification of actinides from lanthanides, separation of metal ions based on their valence, and separation of metal ions based on the pH of the extraction conditions.
FILED Tuesday, March 26, 2019
APPL NO 16/365132
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Peptides
C07K 14/47 (20130101)

Nuclear Reactors
G21C 19/46 (20130101)

Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor
G21F 9/00 (20130101)
G21F 9/125 (20130101) Original (OR) Class

Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management
Y02W 30/50 (20150501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12002605 Zhang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Yuepeng Zhang (Naperville, Illinois);  John N. Hryn (Hawthorn Woods, Illinois);  Yunsong Xie (Austin, Texas)
ABSTRACT Magnetic nanowire components may be used in passive radio-frequency device allowing for smaller size devices, lower power consumption, and on-chip packaging potential across a wide range of technologies. A method for fabricating magnetic nanowire component electronic devices include depositing a conductive device pattern and transmission lines onto a substrate, aligning and securing a magnetic nanowire component to the device pattern, packaging the device with an insulation layer. Alternatively, the conductive device pattern and transmission lines may be deposited on the magnetic nanowire component, and the magnetic nanowire component may then be attached to a substrate.
FILED Tuesday, February 16, 2021
APPL NO 17/176506
ART UNIT 2896 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 25/00 (20130101)
B82Y 40/00 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 1/006 (20130101)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 1/0081 (20130101) Original (OR) Class
H01F 1/143 (20130101)
H01F 41/30 (20130101)
H01F 41/0253 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12002613 Dede et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Toyota Motor Engineering and Manufacturing North America, Inc. (Plano, Texas);  University of Colorado Boulder (Boulder, Colorado)
ASSIGNEE(S)
INVENTOR(S) Ercan M. Dede (Ann Arbor, Michigan);  Tsuyoshi Nomura (Novi, Michigan);  Robert Erickson (Boulder, Colorado);  Dragan Maksimovic (Boulder, Colorado);  Vivek Sankaranarayanan (Boulder, Colorado);  Yucheng Gao (Boulder, Colorado);  Aritra Ghosh (Boulder, Colorado)
ABSTRACT Embodiments of the disclosure relate to apparatuses for enhanced thermal management of a planar inductor assembly. In one embodiment, a cooling package for an inductor assembly includes a cold plate and a heat-spreading bracket mechanically coupled to the cold plate at a first end of the heat-spreading bracket. The cold plate has a slotted recess for mounting a first inductor core along a first end thereof. The heat-spreading bracket is configured to apply a clamping force to a second inductor core at a second end opposite to the first end of the heat-spreading bracket.
FILED Friday, November 22, 2019
APPL NO 16/692370
ART UNIT 2841 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 27/18 (20130101)
H01F 27/22 (20130101) Original (OR) Class
H01F 27/266 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/209 (20130101)
H05K 7/20336 (20130101)
H05K 7/20854 (20130101)
H05K 7/20881 (20130101)
H05K 7/20936 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12002936 Pan et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois);  Michigan Technological University (Houghton, Michigan)
ASSIGNEE(S) UChicago Argonne, LLC (Chicago, Illinois);  Michigan Technological University (Houghton, Michigan)
INVENTOR(S) Lei Pan (Houghton, Michigan);  Tinuade Ololade Folayan (Houghton, Michigan);  Jeffrey S. Spangenberger (Naperville, Illinois);  Bryant J. Polzin (Deerfield, Illinois)
ABSTRACT Method of separating individual cathode active materials from a mixture of cathode active materials by froth flotation has been developed. They are based on using appropriate chemical reagents that selectively hydrophobize individual cathode active materials to be recovered, so that they can be collected by air bubbles used in flotation and separated from other mixtures. The chemical reagents are amphiphilic molecules with specialized head groups have a strong affinity to metal elements on surfaces of cathode materials. This method enables a separation of individual cathode active material from a mixture of cathode active materials.
FILED Tuesday, August 04, 2020
APPL NO 16/985028
ART UNIT 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Flotation; Differential Sedimentation
B03D 1/023 (20130101)
B03D 2201/02 (20130101)
B03D 2201/04 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 25/45 (20130101)

Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 53/42 (20130101)
C01G 53/44 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2006/40 (20130101)
C01P 2006/80 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/54 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 2004/028 (20130101)

Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management
Y02W 30/84 (20150501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12002957 Siu et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) The Research Foundation for The State University of New York (Binghamton, New York)
ASSIGNEE(S) The Research Foundation for The State University of New York (Binghamton, New York)
INVENTOR(S) Carrie Siu (Philadelphia, Pennsylvania);  M. Stanley Whittingham (Vestal, New York)
ABSTRACT The epsilon polymorph of vanadyl phosphate, ε-VOPO4, made from the solvothermally synthesized H2VOPO4, is a high density cathode material for lithium-ion batteries optimized to reversibly intercalate two Li-ions to reach the full theoretical capacity at least 50 cycles with a coulombic efficiency of 98%. This material adopts a stable 3D tunnel structure and can extract two Li-ions per vanadium ion, giving a theoretical capacity of 305 mAh/g, with an upper charge/discharge plateau at around 4.0 V, and one lower at around 2.5 V.
FILED Tuesday, July 18, 2023
APPL NO 18/354493
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 25/372 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/72 (20130101)
C01P 2002/90 (20130101)
C01P 2004/03 (20130101)
C01P 2004/04 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/136 (20130101)
H01M 4/623 (20130101)
H01M 4/625 (20130101)
H01M 4/1397 (20130101)
H01M 4/5825 (20130101) Original (OR) Class
H01M 10/0525 (20130101)
H01M 2004/021 (20130101)
H01M 2004/028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12003114 Sun et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia)
ASSIGNEE(S) VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia)
INVENTOR(S) Keyao Sun (Blacksburg, Virginia);  Jun Wang (Blacksburg, Virginia);  Rolando Burgos (Blacksburg, Virginia);  Dushan Boroyevich (Blacksburg, Virginia)
ABSTRACT Aspects of an efficient compensation network for reducing reactive power in a wireless power transfer (WPT) system are disclosed. The compensation network comprises a series/series (S/S) constant current (CC) source, a reactive power compensation capacitor, and a constant current (CC)-to-constant voltage (CV) network. In an example, the S/S CC source comprises a first capacitor connected in series with a first inductor on a primary side of a transformer and a second inductor on a secondary side of the transformer. The S/S CC source converts an input voltage signal of the WPT system into a constant alternating current (AC) current signal. In an example, the CC-to-CV network comprises at least a third capacitor and a third inductor. The CC-to-CV network converts the constant AC current signal into a constant AC voltage signal.
FILED Friday, June 26, 2020
APPL NO 16/913066
ART UNIT 2839 — Semiconductors/Memory
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/12 (20160201) Original (OR) Class

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 7/5387 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12003272 DeVore et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Peter Thomas Setsuda DeVore (Livermore, California);  Apurva Shantharaj Gowda (Mountain View, California);  David Simon Perlmutter (Oakland, California);  Joshua Linne Olson (Manassas, Virginia);  Jason Thomas Chou (Walnut Creek, California)
ABSTRACT Methods, devices and systems for providing accurate measurements of timing errors using optical techniques are described. An example timing measurement device includes an optical hybrid that receives two optical pulse trains and produces two or more phase shifted optical outputs. The timing measurement device further includes two or more optical filters that receive the outputs of the optical hybrid to produce multiple pulse signals with distinctive frequency bands. The device also includes one or more photodetectors and analog-to-digital converters to receive to produce electrical signals in the digital domain corresponding to the optical outputs of the hybrid. A timing error associated with the optical pulse trains can be determined using the electrical signals in digital domain based on a computed phase difference between a first frequency band signal and a second frequency band signal and a computed frequency difference between the first frequency band signal and the second frequency band.
FILED Wednesday, February 09, 2022
APPL NO 17/667999
ART UNIT 2637 — Optical Communications
CURRENT CPC
Transmission
H04B 10/0795 (20130101) Original (OR) Class
H04B 10/2575 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12003411 Beecroft et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Spring, Texas)
INVENTOR(S) Jonathan P. Beecroft (Bristol, United Kingdom);  Edwin L. Froese (Burnaby, Canada)
ABSTRACT Systems and methods are provided for “on the fly” routing of data transmissions in the presence of errors. Switches can establish flow channels corresponding to flows in the network. In response to encountering a critical error on a network link along a transmission path, a switch can generate an error acknowledgement. The switch can transmit the error acknowledgements to ingress ports upstream from the network link via the plurality of flow channels. By transmitting the error acknowledgement, it indicates that the network link where the critical error was encountered is a failed link to ingress ports upstream from the failed link. Subsequently, each ingress port upstream from the failed link can dynamically update the path of the plurality of flows that are upstream from the failed link such that the plurality of flows that are upstream from the failed link are routed in a manner that avoids the failed link.
FILED Monday, March 23, 2020
APPL NO 17/594712
ART UNIT 2478 — Multiplex and VoIP
CURRENT CPC
Electric Digital Data Processing
G06F 9/505 (20130101)
G06F 9/546 (20130101)
G06F 12/0862 (20130101)
G06F 12/1036 (20130101)
G06F 12/1063 (20130101)
G06F 13/14 (20130101)
G06F 13/16 (20130101)
G06F 13/385 (20130101)
G06F 13/1642 (20130101)
G06F 13/1673 (20130101)
G06F 13/1689 (20130101)
G06F 13/4022 (20130101)
G06F 13/4068 (20130101)
G06F 13/4221 (20130101)
G06F 15/17331 (20130101)
G06F 2212/50 (20130101)
G06F 2213/0026 (20130101)
G06F 2213/3808 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0083 (20130101)
H04L 43/10 (20130101)
H04L 43/0876 (20130101)
H04L 45/02 (20130101)
H04L 45/16 (20130101)
H04L 45/20 (20130101)
H04L 45/021 (20130101)
H04L 45/22 (20130101)
H04L 45/24 (20130101)
H04L 45/028 (20130101)
H04L 45/28 (20130101) Original (OR) Class
H04L 45/38 (20130101)
H04L 45/42 (20130101)
H04L 45/46 (20130101)
H04L 45/70 (20130101)
H04L 45/122 (20130101)
H04L 45/123 (20130101)
H04L 45/125 (20130101)
H04L 45/566 (20130101)
H04L 45/745 (20130101)
H04L 45/7453 (20130101)
H04L 47/11 (20130101)
H04L 47/12 (20130101)
H04L 47/18 (20130101)
H04L 47/20 (20130101)
H04L 47/22 (20130101)
H04L 47/24 (20130101)
H04L 47/30 (20130101)
H04L 47/32 (20130101)
H04L 47/34 (20130101)
H04L 47/39 (20130101)
H04L 47/52 (20130101)
H04L 47/76 (20130101)
H04L 47/80 (20130101)
H04L 47/122 (20130101)
H04L 47/323 (20130101)
H04L 47/621 (20130101)
H04L 47/626 (20130101)
H04L 47/629 (20130101)
H04L 47/762 (20130101)
H04L 47/781 (20130101)
H04L 47/2441 (20130101)
H04L 47/2466 (20130101)
H04L 47/2483 (20130101)
H04L 47/6235 (20130101)
H04L 47/6275 (20130101)
H04L 49/15 (20130101)
H04L 49/30 (20130101)
H04L 49/90 (20130101)
H04L 49/101 (20130101)
H04L 49/3009 (20130101)
H04L 49/3018 (20130101)
H04L 49/3027 (20130101)
H04L 49/9005 (20130101)
H04L 49/9021 (20130101)
H04L 49/9036 (20130101)
H04L 49/9047 (20130101)
H04L 67/1097 (20130101)
H04L 69/22 (20130101)
H04L 69/28 (20130101)
H04L 69/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12004286 Romanenko et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Fermi National Accelerator Laboratory (FNAL)
Federally Funded Research and Development Center (FFRDC)
Operated by Fermi Research Alliance, LLC (FRA) at Batavia, IL
APPLICANT(S) FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois)
ASSIGNEE(S) Fermi Research Alliance, LLC (Batavia, Illinois)
INVENTOR(S) Alexander Romanenko (Batavia, Illinois);  Sam Posen (Arlington Heights, Illinois);  Anna Grassellino (Batavia, Illinois)
ABSTRACT A system and method for treating a cavity comprises preparing a superconducting radio frequency (SRF) cavity for removal of a dielectric layer from on an inner surface of the SRF cavity, subjecting the SRF cavity to a heat treatment in order to remove the dielectric layer from the inner surface of the SRF cavity, and preventing the development of a new dielectric layer on the inner surface of the SRF cavity by preventing an interaction between the inner surface of the SRF cavity and atmospheric gasses.
FILED Monday, August 29, 2022
APPL NO 17/898065
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type
H01P 7/06 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 7/20 (20130101) Original (OR) Class

Electric solid-state devices not otherwise provided for
H10N 60/01 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12004332 Moreno et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  BorgWarner, Inc. (Auburn Hills, Michigan)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  BorgWarner, Inc. (Auburn Hills, Michigan)
INVENTOR(S) Gilberto Moreno (Thornton, Colorado);  Sreekant Venkat Jagannath Narumanchi (Golden, Colorado);  Xuhui Feng (Golden, Colorado);  Ammar Osman (Golden, Colorado);  Steve Michael Myers (Oxford, Michigan);  Brian James Kelly (Lakewood, Colorado);  Paul Philip Paret (Denver, Colorado)
ABSTRACT The present disclosure relates generally to methods and devices for the cooling (or removal of heat from) power electronics modules in automotive vehicles, wherein the cooling is done by positioning the power electronics module in a housing, directing a fluid into the housing, and impinging the fluid onto the power electronics module and/or an electrical connection in contact with the power electronics module.
FILED Tuesday, January 11, 2022
APPL NO 17/573445
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles
B60K 11/02 (20130101)

Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 2/08 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 23/473 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 7/209 (20130101)
H05K 7/20272 (20130101)
H05K 7/20927 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 11998007 Kaeppler et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Systems (IOS)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Shawn Kaeppler (Middleton, Wisconsin);  Heidi Kaeppler (Middleton, Wisconsin);  Michael William Petersen (Merrimac, Wisconsin);  Brian Joseph Martinell (Mount Horeb, Wisconsin);  Frank McFarland (Middleton, Wisconsin)
ABSTRACT A maize pollen composition containing polyether ether ketone and pollen for collecting pollen and storing pollen.
FILED Monday, March 14, 2022
APPL NO 17/694200
ART UNIT 1661 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 5/10 (20130101)
A01H 6/4684 (20180501)

Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 3/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998439 Allen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Science Foundation (NSF)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Robert Andrew Allen (Pittsburgh, Pennsylvania);  Chelsea Elizabeth Stowell (Pittsburgh, Pennsylvania);  Yadong Wang (Allison Park, Pennsylvania)
ABSTRACT A method of fabricating a vascular graft that includes preparing a biodegradable polyester electrospun tubular core; applying an adhesive composition comprising poly(lactide) copolymer to an outer surface of the biodegradable polyester electrospun tubular core; and surrounding the adhesive-applied biodegradable polyester electrospun tubular core with a polyester sheath.
FILED Tuesday, February 18, 2020
APPL NO 16/793355
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/06 (20130101)
A61F 2/07 (20130101) Original (OR) Class

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/14 (20130101)
A61L 27/18 (20130101)
A61L 27/18 (20130101)
A61L 27/24 (20130101)
A61L 27/54 (20130101)
A61L 27/58 (20130101)
A61L 27/222 (20130101)
A61L 27/225 (20130101)
A61L 27/507 (20130101)

Compositions of Macromolecular Compounds
C08L 67/04 (20130101)

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/0007 (20130101)
D01D 5/0076 (20130101)
D01D 5/0084 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 11/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998443 Birge et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) LambdaVision Incorporated (Farmington, Connecticut)
ASSIGNEE(S) LambdaVision Incorporated (Farmington, Connecticut)
INVENTOR(S) Robert R Birge (Peyton, Colorado);  Nicole Wagner (Ashford, Connecticut);  Jordan A Greco (Rocky Hill, Connecticut)
ABSTRACT Protein-based subretinal implants offer a new approach to restoring vision for patients blinded by conditions such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP). The present invention relates to bacteriorhodopsin-based (BR-based) retinal implants that can be implanted in a subretinal position to replace degenerated photoreceptor cells.
FILED Tuesday, May 08, 2018
APPL NO 16/611095
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/14 (20130101) Original (OR) Class
A61F 9/0017 (20130101)
A61F 2009/00863 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 38/164 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/227 (20130101)
A61L 2300/252 (20130101)
A61L 2430/16 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/36046 (20130101)
A61N 5/0603 (20130101)
A61N 5/0622 (20130101)
A61N 2005/0648 (20130101)
A61N 2005/0663 (20130101)

Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/0073 (20130101)

Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 7/023 (20190101)
B32B 2535/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998609 Cui et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Honggang Cui (Baltimore, Maryland);  Charles Williams Flexner (Baltimore, Maryland);  Maya Monroe (Baltimore, Maryland);  Han Wang (Baltimore, Maryland)
ABSTRACT Disclosed are therapeutic self-assembling molecules including a peptide sequence conjugated to one or more antiviral therapeutics to form a peptide-based antiviral prodrug capable of self-assembly into supramolecular structures with varying morphology in aqueous solutions, which can be injected subcutaneously or intramuscularly for the long-acting treatment of chronic viral infections.
FILED Monday, November 07, 2022
APPL NO 17/981595
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/64 (20170801) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)
A61P 31/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998915 Vanapalli et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Texas Tech University System (Lubbock, Texas)
ASSIGNEE(S) TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas)
INVENTOR(S) Siva A. Vanapalli (Lubbock, Texas);  Swastika S. Bithi (Lubbock, Texas)
ABSTRACT A microfluidic device includes a substrate and a cover. The substrate has an inlet port, a first microchannel, one or more parking loops, a second microchannel and an outlet port for each microchannel network. The first microchannel is connected to the inlet port, the second microchannel is connected to the outlet port, the parking loops are connected between the first and second microchannels. Each parking loop includes a parking loop inlet, a parking loop output, a fluidic trap connected between the parking loop inlet and the parking loop outlet, and a bypass microchannel connected to the parking loop inlet and the parking loop outlet. The cover is attached to a top of the substrate and has an inlet opening and an outlet opening through the cover for each microchannel network. The inlet and outlet openings of the cover are disposed above the inlet and outlet ports in the substrate.
FILED Tuesday, October 06, 2020
APPL NO 17/063806
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502707 (20130101)
B01L 3/502715 (20130101)
B01L 3/502746 (20130101)
B01L 3/502761 (20130101)
B01L 3/502784 (20130101) Original (OR) Class
B01L 2200/12 (20130101)
B01L 2200/142 (20130101)
B01L 2300/041 (20130101)
B01L 2300/087 (20130101)
B01L 2300/088 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0887 (20130101)
B01L 2400/049 (20130101)
B01L 2400/084 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999146 Hemnani et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
APPLICANT(S) The George Washington University (Washington, District of Columbia)
ASSIGNEE(S) The George Washington University (Washington, District of Columbia)
INVENTOR(S) Rohit Anil Hemnani (Washington, District of Columbia);  Volker J. Sorger (Alexandria, Virginia)
ABSTRACT Precision and chip contamination-free placement of two-dimensional (2D) material and van der Waals (VDW) layered materials accelerates both the study of fundamental properties and novel device functionality. The system transfers 2D materials utilizing a combination of a narrow transfer-stamper and viscoelastic and optically transparent film. Precise placement of individual 2D materials results in vanishing cross-contamination to the substrate. The 2D printer results in an aerial cross-contamination improvement of two to three orders of magnitude relative to state-of-the-art transfer methods from a source of average area sub um{circumflex over ( )}2. The transfer-stamper does not physically harm any micro/nanostructures preexisting on the target substrates receiving the 2D material such as, nanoelectronics, waveguides or micro-ring resonators. Such accurate and substrate-benign transfer method for 2D and VDW layered materials provides rapid device prototyping due to its high time-reduction, accuracy, and contamination-free process.
FILED Monday, February 15, 2021
APPL NO 17/176142
ART UNIT 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form
B32B 37/025 (20130101) Original (OR) Class
B32B 41/00 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)
B82Y 40/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/762 (20130101)
H01L 29/778 (20130101)
H01L 29/1606 (20130101)
H01L 29/66045 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999650 Thostenson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Office of Polar Programs (OPP)
The Office of Polar Programs Antarctic (ANT)
Department of Transportation (USDOT)
Federal Highway Administration (FHWA)
National Highway Traffic Safety Administration (NHTSA)
APPLICANT(S) UNIVERSITY OF DELAWARE (Newark, Delaware)
ASSIGNEE(S)
INVENTOR(S) Erik Thostenson (Newark, Delaware);  Thomas Schumacher (Portland, Oregon)
ABSTRACT Processes for depositing functionalized nanoparticles upon a non-conductive substrate are disclosed herein. The processes may include the step of aerosolizing one or more particles into suspension within a gas, each of the one or more particles comprising functionalized nanoparticles having an electric charge. The processes may include the step the step of attracting the one or more particles onto a non-conductive substrate by a static electric charge opposite of the electric charge, wherein at least portions of the non-conductive substrate are having the static electric charge. The processes may include the step of depositing the functionalized nanoparticles onto the non-conductive substrate.
FILED Wednesday, November 09, 2022
APPL NO 17/983818
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 25/44 (20130101) Original (OR) Class

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/041 (20170501)
C08K 3/042 (20170501)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/4419 (20130101)
C09D 7/61 (20180101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 13/02 (20130101)
C25D 13/12 (20130101)
C25D 13/22 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/254 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999836 Smalyukh et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S)
INVENTOR(S) Ivan I. Smalyukh (Boulder, Colorado);  Andrew Johnston Hess (Louisville, Colorado);  Quingkun Liu (Boulder, Colorado);  Joshua A. De La Cruz (Denver, Colorado);  Blaise Fleury (Boulder, Colorado);  Eldho Abraham (Boulder, Colorado);  Bohdan Senyuk (Boulder, Colorado);  Vladyslav Cherpak (Westminster, Colorado)
ABSTRACT Disclosed are cellulose-based 5 flexible aerogels and xerogels containing bacterial cellulose nanorods, ribbons, fibers, and the like, wherein the gels have tunable optical, heat transfer, and stiffness properties. Further disclosed are highly transparent and flexible cellulose nanofiber-polysiloxane composite aerogels featuring enhanced mechanical robustness, tunable optical anisotropy, and low thermal conductivity.
FILED Thursday, June 13, 2019
APPL NO 17/251694
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 5/18 (20130101)
C08J 9/28 (20130101) Original (OR) Class
C08J 2201/026 (20130101)
C08J 2201/0504 (20130101)
C08J 2205/026 (20130101)
C08J 2205/028 (20130101)
C08J 2301/02 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/544 (20130101)
C08K 7/02 (20130101)
C08K 2201/011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999954 Han et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Science Foundation (NSF)
APPLICANT(S) CITY OF HOPE (Duarte, California);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) Clty of Hope (Duarte, California);  California Institute of Technology (Pasadena, California)
INVENTOR(S) Si-ping Han (Duarte, California);  William A. Goddard, III (Pasadena, California);  Marwa Ben Haj Salah (Duarte, California);  Lisa Scherer (Duarte, California);  John J. Rossi (Duarte, California)
ABSTRACT Disclosed herein are programmable, conditionally activated small interfering RNA constructs (Cond-siRNAs) and methods of making and using the same as therapeutic agents. The Cond-siRNA comprises a sensor strand, a core strand, and a guide strand, which crossover to form a sensor duplex and a RNAi duplex attached to each other to form a single structure. Upon binding an input strand to the sensor strand, the Cond-siRNA is activated and releases RNAi targeting a desired gene.
FILED Wednesday, February 10, 2021
APPL NO 17/172461
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101) Original (OR) Class
C12N 2310/141 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999966 Hjort et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
National Science Foundation (NSF)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Karl Martin Hjort (Lund, Sweden);  Sergio Leal-Ortiz (Hayward, California);  Yuhong Cao (Palo Alto, California);  Chris Rehse (Palo Alto, California);  Andy Kah Ping Tay (Stanford, California);  Nicholas A. Melosh (Menlo Park, California)
ABSTRACT Nanostraws and to methods of utilizing them in order to deliver biologically relevant molecules such as DNA, RNA, proteins etc., into non-adherent cells such as immune cells, embryos, plant cells, bacteria, yeast etc. The methods described herein are repeatedly capable of delivering biologically relevant cargo into non-adherent cells, with high cell viability, dosage control, unaffected proliferation or cellular development, and with high efficiency. Among other uses, these new delivery methods will allow to scale pre-clinical cell reprogramming techniques to clinical applications.
FILED Tuesday, October 27, 2020
APPL NO 17/081983
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 40/00 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/02 (20130101)
C12M 23/16 (20130101)
C12M 23/42 (20130101)
C12M 35/00 (20130101)
C12M 35/02 (20130101)
C12M 35/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 5/0075 (20130101)
C12N 15/87 (20130101) Original (OR) Class
C12N 2521/00 (20130101)
C12N 2535/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000037 Maschmann et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Curators of the University of Missouri (Columbia, Missouri)
ASSIGNEE(S) The Curators of the University of Missouri (Columbia, Missouri)
INVENTOR(S) Matthew R. Maschmann (Columbia, Missouri);  Matthias J. Young (Columbia, Missouri)
ABSTRACT A method of depositing a nanoscale-thin film onto a substrate is disclosed. The method generally comprises depositing a layer of a solid or gaseous state functionalizing molecule onto or adjacent to the first surface of the substrate and exposing the first surface to a source of ionizing radiation, thereby functionalizing the first surface of the substrate. Once the layer of functionalizing molecule is removed, a nanoscale-thin film is then deposited onto the functionalized first surface of the substrate.
FILED Friday, December 23, 2022
APPL NO 18/146043
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/20 (20130101)
C23C 16/0263 (20130101) Original (OR) Class
C23C 16/403 (20130101)
C23C 16/45527 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000058 Akkus et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Ozan Akkus (Cleveland Heights, Ohio);  Mousa Younesi (Shaker Heights, Ohio);  Umit Levent Erol (Cleveland Heights, Ohio)
ABSTRACT A method for producing an electrocompacted and aligned strand is disclosed. The method includes the steps of: providing a channel having an anode on one side and a cathode on the other side separated by a non-conductive material to form an electrode; dispensing a solution comprising one or more electrocompactable and alignable molecules, nanoparticles or microparticles with ampholytic nature into the channel to complete a circuit between the anode and the cathode; applying a DC current in the range of 1-200 volts to the electrode through the solution in the channel to form an electrocompacted and aligned strand; and transferring the aligned strand out of the electrode. The one or more electrocompactable and alignable molecules, nanoparticles or microparticles with ampholytic nature can comprise collagen molecules that have different charges at different pH values. Materials including electrochemically aligned and compacted compounds are also disclosed.
FILED Wednesday, February 15, 2023
APPL NO 18/169365
ART UNIT 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 1/04 (20130101) Original (OR) Class

Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons
D01D 5/00 (20130101)
D01D 10/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000449 Bonessio
FUNDED BY
National Science Foundation (NSF)
Directorate of Technology, Innovation and Partnerships (TIP)
Translational Impacts (TI)
APPLICANT(S) METAseismic, Inc. (Berkeley, California)
ASSIGNEE(S) METAseismic, Inc. (Berkeley, California)
INVENTOR(S) Noemi Bonessio (Berkeley, California)
ABSTRACT A tri-adaptive apparatus is disclosed and configured for functioning as a dynamic force isolation and dampening metamaterial that reduces the transmission of dynamic forces between a dynamic force source and an object. In at least one embodiment, the apparatus provides at least one cell unit that provides a pair of opposing first and second cell plates, between which is positioned at least one spring, restrainer and dashpot. An outer surface of the first cell plate is positioned in contact with the dynamic force source. An outer surface of the second cell plate is positioned in contact with the object. The at least one spring, restrainer and dashpot are configured for transferring dynamic force energy mutually between one another while deforming mechanically in response to the dynamic forces transmitted by the dynamic force source.
FILED Wednesday, June 07, 2023
APPL NO 18/206758
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Springs; Shock-absorbers; Means for Damping Vibration
F16F 13/04 (20130101) Original (OR) Class
F16F 2228/066 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000609 Li et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Da Li (Clemson, South Carolina);  Carol C. Menassa (Ann Arbor, Michigan);  Vineet Kamat (Ann Arbor, Michigan)
ABSTRACT A method of making a thermal comfort estimation of one or more human occupants in a built space in real-time is presented. The method employs one or more thermographic cameras and one or more red, green, and blue depth (RGB-D) sensors. The method has several steps. In an example, the method involves capturing thermal images of the human occupant(s) via the thermographic camera(s) and capturing RGB-D images of the human occupant(s) via the RGB-D camera(s). The method further involves extracting facial skin temperatures of the human occupant(s) using the captured thermal images and using the captured RGB-D images. And the method involves estimating the thermal comfort of the human occupant(s) using the extracted facial skin temperatures.
FILED Thursday, January 09, 2020
APPL NO 17/422142
ART UNIT 2425 — Cable and Television
CURRENT CPC
Arrangements of Heating, Cooling, Ventilating or Other Air-treating Devices Specially Adapted for Passenger or Goods Spaces of Vehicles
B60H 1/00742 (20130101)

Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening
F24F 11/63 (20180101) Original (OR) Class
F24F 2120/10 (20180101)

Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 5/0025 (20130101)

Image Data Processing or Generation, in General
G06T 7/33 (20170101)
G06T 2207/10024 (20130101)
G06T 2207/10028 (20130101)
G06T 2207/10048 (20130101)
G06T 2207/30201 (20130101)
G06T 2207/30232 (20130101)

Image or Video Recognition or Understanding
G06V 40/10 (20220101)

Pictorial Communication, e.g Television
H04N 23/90 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000740 Cao et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Yunqi Cao (Pasadena, California);  Nelson Sepulveda-Alancastro (Haslett, Michigan);  Henry D'Souza (East Lansing, Michigan)
ABSTRACT A sensor apparatus is provided. Multiple opposite and self-powered sensors are provided in another aspect of the present apparatus. A further aspect employs a sensor apparatus including a first pair of flexible piezoelectric sensors attached to opposite sides of an exterior surface of a workpiece and at least a second pair of flexible piezoelectric sensors attached to opposite sides of the exterior surface of the workpiece. Another aspect of the present apparatus uses pairs of thin film piezoelectric sensors which are configured to detect bending curvature of a workpiece in at least two dimensions by sending voltage output signals from both of the sensors of a first pair and/or both of the sensors of at least a second pair to a controller and/or electrical circuit.
FILED Tuesday, November 16, 2021
APPL NO 17/527478
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/16 (20130101) Original (OR) Class
G01L 5/0052 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 3/066 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000809 Anderson et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
INVENTOR(S) Jared L. Anderson (Ames, Iowa);  Kosuke Kuroda (Kanazawa, Japan);  He Nan (Ames, Iowa)
ABSTRACT A gas chromatographic (GC) column using a zwitterionic compound and methods of use thereof are disclosed herein. The volatile free acids were observed to strongly retain on these zwitterionic compounds-based columns with excellent peak symmetry. By carefully tuning the structures of these zwitterionic compounds, different selectivity toward volatile free acids was demonstrated. These stationary phases possess a wide working range with thermal stabilities at higher temperatures.
FILED Monday, May 09, 2022
APPL NO 17/662512
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Separation
B01D 15/36 (20130101)

Heterocyclic Compounds
C07D 233/60 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/56 (20130101) Original (OR) Class
G01N 30/68 (20130101)
G01N 30/72 (20130101)
G01N 30/74 (20130101)
G01N 2030/025 (20130101)
G01N 2030/562 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000878 Chini et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
National Science Foundation (NSF)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Michael Chini (Orlando, Florida);  Yangyang Liu (Orlando, Florida);  Shima Gholam-Mirzaei (Orlando, Florida);  John Beetar (Orlando, Florida);  Jonathan Nesper (Orlando, Florida)
ABSTRACT A laser diagnostic device may include a beamsplitter to split one or more input pulses into one or more fundamental pulses and one or more perturbing pulses, one or more beam-combining optics to combine the fundamental and perturbing pulses at a detection plane, a detector including a solid-state material at the detection plane, and a controller. The controller may receive a detector signal from the detector is indicative of nonlinear absorption in the solid-state medium of the fundamental pulses that is perturbed by the perturbing pulses. The controller may further extract a temporal electric field waveform of the one or more input pulses from the detector signal and provide as an output at least one of the temporal electric field waveform, a spectrum, or a spectral phase of the one or more input pulses.
FILED Monday, March 07, 2022
APPL NO 17/688637
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/443 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 29/12 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 27/108 (20130101)

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/3551 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12001028 Wang et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
INVENTOR(S) Xiaoxin Wang (Hanover, New Hampshire);  Charles J. Carver, Jr. (Hanover, New Hampshire);  Eric R. Fossum (Hanover, New Hampshire);  Jifeng Liu (Hanover, New Hampshire);  Xia Zhou (Hanover, New Hampshire);  Nicholas R. Shade (Hanover, New Hampshire)
ABSTRACT A speckle-suppressing lighting system includes an optical waveguide, a first solid-state light source, a second solid-state light source, and a diffuser. The optical waveguide has a proximal end and a distal end. At least part of the diffuser is between the proximal end and the distal end. The first solid-state light source is optically coupled to the optical waveguide near the proximal end, and emits a first light beam that propagates toward the distal end and has a first center wavelength. The second solid-state light source is optically coupled to the optical waveguide near the proximal end, and emits a second light beam that propagates toward the distal end and has a second center wavelength differing from the first center wavelength. The diffuser diffuses the first light beam and the second light beam.
FILED Monday, September 26, 2022
APPL NO 17/953129
ART UNIT 2875 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/0006 (20130101)
G02B 6/0008 (20130101)
G02B 27/48 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12001867 Shen et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Zhiming Shen (Ithaca, New York);  Robbert van Renesse (Ithaca, New York);  Hakim Weatherspoon (Ithaca, New York)
ABSTRACT A method in one embodiment comprises implementing a kernel-based isolation layer, configuring a software container on the kernel-based isolation layer to include a dedicated operating system kernel as a library operating system, and executing one or more user processes in the software container. The method is performed by a cloud-based processing platform, an enterprise processing platform, or other type of processing platform comprising a plurality of processing devices, with each such processing device comprising a processor coupled to a memory. The library operating system illustratively runs in the software container at a privilege level that is the same as a privilege level of the one or more user processes executing in the software container. The library operating system is illustratively configured to support automatic translation of binaries of the one or more user processes in conjunction with converting system calls into corresponding function calls.
FILED Thursday, April 11, 2019
APPL NO 17/046632
ART UNIT 2196 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/545 (20130101)
G06F 9/4555 (20130101)
G06F 9/45558 (20130101) Original (OR) Class
G06F 2009/45587 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12002877 Li et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) The Research Foundation for the State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for the State University of New York (Albany, New York)
INVENTOR(S) Huamin Li (Buffalo, New York);  Fei Yao (Buffalo, New York)
ABSTRACT Field effect transistors (FET) including quantum layers. A FET may include a substrate, and an oxide layer disposed over the substrate. The oxide layer may include a first section and a second section positioned adjacent the first section. The FET may also include a first quantum layer disposed over the first section of the oxide layer, and a second quantum layer disposed over the second section of the oxide layer, and a first segment of the first quantum layer. Additionally, the FET may include a drain region disposed directly over a second segment the first quantum layer. The second segment of the first quantum layer may be positioned adjacent the first segment of the first quantum layer. The FET may further include a source region disposed over the second quantum layer, and a channel region formed over the second quantum layer, between the drain region and the source region.
FILED Friday, June 25, 2021
APPL NO 17/358500
ART UNIT 2898 — Semiconductors/Memory
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 29/775 (20130101) Original (OR) Class
H01L 29/41733 (20130101)
H01L 29/42384 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12003502 Traynor et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida)
INVENTOR(S) Patrick G. Traynor (Gainesville, Florida);  Christian Peeters (Gainesville, Florida);  Christopher Patton (San Francisco, California);  Imani Sherman (Cincinnati, Ohio);  Daniel Olszewski (Gainesville, Florida);  Thomas Shrimpton (Gainesville, Florida)
ABSTRACT Various methods are provided for secure two-factor authentication, and more specifically, for incorporating a layer of security to two-factor authentication using Short Message Service in a manner virtually transparent to the end-user. Methods may include receiving a request for registration for two-factor authentication from a client including a username and password; providing a request for a mobile device number; receiving the mobile device number and a pre-shared key; sending to a mobile device an identity of the client and a server key share; receiving from the mobile device a mobile device key share; sending information corresponding to an exchange with the mobile device and a challenge derived from the pre-shared key to the client in response to the device key share corresponding to the server key share; receiving confirmation of registration with the mobile device; and establishing a shared key in response to verification of the confirmation.
FILED Thursday, August 26, 2021
APPL NO 17/446023
ART UNIT 2495 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/166 (20130101)
H04L 63/0435 (20130101)
H04L 63/0838 (20130101) Original (OR) Class
H04L 2463/082 (20130101)

Wireless Communication Networks
H04W 4/14 (20130101)
H04W 12/069 (20210101)
H04W 12/0431 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 11998520 Weinberg
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) ResQ Pharma, Inc. (Chicago, Illinois)
ASSIGNEE(S) The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Guy Weinberg (Chicago, Illinois)
ABSTRACT The present disclosures provides methods for decreasing injuries associated with intraoperative hypotension by intravenously administering to a subject a therapeutically effective amount of a fat emulsion, following a period of intraoperative hypotension and after the subject's mean arterial blood pressure has recovered. The disclosure also provides methods for preventing injuries associated with intraoperative hypotension, particularly for surgical candidates that have an increased risk for intraoperative hypotension. Non-limiting examples of injuries contemplated herein include myocardial injury, myocardial infarction, and acute kidney injury.
FILED Friday, September 03, 2021
APPL NO 17/466778
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/107 (20130101)
A61K 31/201 (20130101) Original (OR) Class
A61K 31/202 (20130101)
A61K 38/085 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11998757 Lohr et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin)
ASSIGNEE(S) The Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin)
INVENTOR(S) Nicole Lohr (New Berlin, Wisconsin);  Michael Salinger (, None)
ABSTRACT Reperfusion injury is limited during endovascular therapies (e.g., revascularization and/or reperfusion of end organ tissues) by conditioning the tissues against reperfusion injury using an optical fiber catheter to deliver far red and near infrared (R/NIR) light to the tissues. The light may be multiple wavelength or single wavelength light, and may have one or more wavelengths selected from the range of 510 to 830 nm. The R/NIR light may be delivered concurrently with the endovascular therapy, or in other instances may be delivered before or after a particular therapy.
FILED Tuesday, March 22, 2022
APPL NO 17/701099
ART UNIT 3796 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/24 (20130101)
A61B 2017/0019 (20130101)
A61B 2018/00351 (20130101)
A61B 2018/00577 (20130101)
A61B 2090/049 (20160201)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/0601 (20130101) Original (OR) Class
A61N 5/0613 (20130101)
A61N 2005/063 (20130101)
A61N 2005/0602 (20130101)
A61N 2005/0651 (20130101)
A61N 2005/0663 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999720 Meroueh et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana);  THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
ASSIGNEE(S) THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana);  THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia)
INVENTOR(S) Samy Meroueh (Carmel, Indiana);  Fletcher A. White (Indianapolis, Indiana);  Alexander G. Obukhov (Carmel, Indiana)
ABSTRACT This invention relates to pyrazolylacylpyrazoline compounds or pharmaceutically acceptable salts thereof, and for the use of the compounds to treat neurological disorders.
FILED Thursday, September 19, 2019
APPL NO 17/251473
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 401/14 (20130101)
C07D 403/04 (20130101) Original (OR) Class
C07D 403/14 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 11999853 Helgason et al.
FUNDED BY
Department of Veterans Affairs (DVA)
DVA Office of Research and Development (DVAORD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Non-Profit Organization (NPO)
Dystrophic Epidermolysis Bullosa Research Association of America (DEBRA of America)
APPLICANT(S) VitroLabs Inc (Milpitas, California);  King's College London (London, United Kingdom)
ASSIGNEE(S) VITROLABS INC (Milpitas, California);  KING'S COLLEGE LONDON (London, United Kingdom)
INVENTOR(S) Ingvar Helgason (South San Francisco, California);  Dusko Ilic (London, United Kingdom)
ABSTRACT Disclosed herein are synthetic leathers, artificial epidermal layers, artificial dermal layers, layered structures, products produced therefrom and methods of producing the same.
FILED Wednesday, July 05, 2023
APPL NO 18/347349
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compositions of Macromolecular Compounds
C08L 89/06 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0625 (20130101)
C12N 5/0629 (20130101)
C12N 5/0698 (20130101)
C12N 11/02 (20130101)
C12N 2501/155 (20130101)
C12N 2501/385 (20130101)
C12N 2502/13 (20130101)
C12N 2502/091 (20130101)
C12N 2502/094 (20130101)
C12N 2506/45 (20130101)
C12N 2533/30 (20130101)
C12N 2533/54 (20130101)

Chemical Treatment of Hides, Skins or Leather, e.g Tanning, Impregnating, Finishing; Apparatus Therefor; Compositions for Tanning
C14C 3/02 (20130101)
C14C 13/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 11999966 Hjort et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
National Science Foundation (NSF)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Karl Martin Hjort (Lund, Sweden);  Sergio Leal-Ortiz (Hayward, California);  Yuhong Cao (Palo Alto, California);  Chris Rehse (Palo Alto, California);  Andy Kah Ping Tay (Stanford, California);  Nicholas A. Melosh (Menlo Park, California)
ABSTRACT Nanostraws and to methods of utilizing them in order to deliver biologically relevant molecules such as DNA, RNA, proteins etc., into non-adherent cells such as immune cells, embryos, plant cells, bacteria, yeast etc. The methods described herein are repeatedly capable of delivering biologically relevant cargo into non-adherent cells, with high cell viability, dosage control, unaffected proliferation or cellular development, and with high efficiency. Among other uses, these new delivery methods will allow to scale pre-clinical cell reprogramming techniques to clinical applications.
FILED Tuesday, October 27, 2020
APPL NO 17/081983
ART UNIT 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)
B82Y 40/00 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/02 (20130101)
C12M 23/16 (20130101)
C12M 23/42 (20130101)
C12M 35/00 (20130101)
C12M 35/02 (20130101)
C12M 35/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0068 (20130101)
C12N 5/0075 (20130101)
C12N 15/87 (20130101) Original (OR) Class
C12N 2521/00 (20130101)
C12N 2535/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12001867 Shen et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Cornell University (Ithaca, New York)
ASSIGNEE(S) Cornell University (Ithaca, New York)
INVENTOR(S) Zhiming Shen (Ithaca, New York);  Robbert van Renesse (Ithaca, New York);  Hakim Weatherspoon (Ithaca, New York)
ABSTRACT A method in one embodiment comprises implementing a kernel-based isolation layer, configuring a software container on the kernel-based isolation layer to include a dedicated operating system kernel as a library operating system, and executing one or more user processes in the software container. The method is performed by a cloud-based processing platform, an enterprise processing platform, or other type of processing platform comprising a plurality of processing devices, with each such processing device comprising a processor coupled to a memory. The library operating system illustratively runs in the software container at a privilege level that is the same as a privilege level of the one or more user processes executing in the software container. The library operating system is illustratively configured to support automatic translation of binaries of the one or more user processes in conjunction with converting system calls into corresponding function calls.
FILED Thursday, April 11, 2019
APPL NO 17/046632
ART UNIT 2196 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/545 (20130101)
G06F 9/4555 (20130101)
G06F 9/45558 (20130101) Original (OR) Class
G06F 2009/45587 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12003031 Manesh et al.
FUNDED BY
Department of Commerce (DOC)
National Oceanic and Atmospheric Administration (NOAA)
APPLICANT(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) Hadi Saeidi Manesh (Norman, Oklahoma);  Guifu Zhang (Norman, Oklahoma)
ABSTRACT A microstrip patch antenna comprising: a unit cell comprising: a plurality of layers comprising: a first laminate comprising one or more horizontal polarization feed lines and one or more vertical polarization feed lines, a second laminate comprising a radiating square patch, and a third laminate comprising a parasitic patch; and a ground plane comprising one or more polarization slots. A differential feed antenna comprising: a balun; a plurality of feed lines; and one or more polarization ports configured to excite at a plurality of locations.
FILED Tuesday, November 10, 2020
APPL NO 17/094421
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/025 (20130101)
G01S 13/95 (20130101)

Antennas, i.e Radio Aerials
H01Q 1/48 (20130101)
H01Q 19/005 (20130101)
H01Q 21/24 (20130101) Original (OR) Class
H01Q 21/0025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 11999462 Hefner et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Neil A Armstrong Flight Research Center (AFRC)
APPLICANT(S) Bell Textron Inc. (Fort Worth, Texas)
ASSIGNEE(S) Textron Innovations Inc. (Providence, Rhode Island)
INVENTOR(S) Levi Hefner (Dallas, Texas);  Maurice Griffin (Boerne, Texas);  Jennifer Diana Andrews (North Richland Hills, Texas)
ABSTRACT In an embodiment, an aircraft includes first and second wings. The aircraft also includes a plurality of propulsion assemblies, the plurality of propulsion assemblies including a propulsion assembly connected to each end of each of the first and second wings. The aircraft also includes first and second vertical supports disposed between the first and second wings. The aircraft also includes a storage pod disposed between the first and second vertical supports. The storage pod includes a nose portion that extends forward of the plurality of propulsion assemblies. The nose portion includes at least one radar and at least one camera. Other embodiments of this aspect include corresponding computer systems, apparatus, and computer programs recorded on one or more computer storage devices, each configured to perform the actions of the methods.
FILED Wednesday, December 09, 2020
APPL NO 17/116778
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 1/36 (20130101)
B64C 1/068 (20130101) Original (OR) Class
B64C 29/02 (20130101)
B64C 39/08 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 9/00 (20130101)
B64D 47/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12000691 Ohanian, III et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) LUNA INNOVATIONS INCORPORATED (Roanoke, Virginia)
ASSIGNEE(S) LUNA INNOVATIONS INCORPORATED (Roanoke, Virginia)
INVENTOR(S) Osgar John Ohanian, III (Blacksburg, Virginia);  Matthew Anthony Davis (Christiansburg, Virginia)
ABSTRACT An apparatus comprises a flexible filament structure, and a fiber optic sensor with a buffer material that locally bonds the fiber optic sensor to the flexible filament structure to create a bond between the fiber optic sensor and the flexible filament structure to transfer strain from the flexible filament structure to the fiber optic sensor to allow the fiber optic sensor to detect strain on the flexible filament structure while maintaining flexibility in the flexible filament structure. A fiber optic interrogator may be optically coupled to the fiber optic sensor and configured to measure strain. A method comprises embedding a fiber optic sensor with a buffer material in or on a flexible filament structure. Thereafter, the buffer material is activated via heating or curing to locally adhere the fiber optic sensor to the flexible filament structure to create a local bond. The local bond transfers strain from the flexible filament structure to the fiber optic sensor.
FILED Thursday, August 27, 2020
APPL NO 17/638458
ART UNIT 2878 — Optics
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/18 (20130101) Original (OR) Class

Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 5/35374 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/246 (20130101)

Optical Elements, Systems, or Apparatus
G02B 6/4298 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12003951 Rafaelof et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Menachem Rafaelof (Yorktown, Virginia);  Kyle Wendling (Henrico, Virginia);  Andrew W. Christian (Hampton, Virginia)
ABSTRACT A statistical audibility prediction (SAP) method for predicting the audibility of a signal over time at a listening location, the signal from a signal source in the presence of a concurrent masking sound or masker from a masker source. The method includes receiving, via a processor over a plurality of auditory channels, a specific loudness of the signal and masker at the listening location. The method includes calculating for each auditory channel a standard deviation of a distribution of the specific loudness of the signal and masker, and calculating, via the processor, corresponding channel-specific detectability indices (d′t,i) for each auditory channel as a function of their standard deviations. The corresponding channel-specific detectability indices are then summed to produce a total detectability index (d′t), which may be output as an electronic signal that indicates the predicted audibility vs. time, e.g., to a downstream process and/or system or offline.
FILED Wednesday, March 30, 2022
APPL NO 17/708575
ART UNIT 2691 — Selective Visual Display Systems
CURRENT CPC
Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for
G10K 11/1752 (20200501)

Stereophonic Systems
H04S 3/008 (20130101)
H04S 7/303 (20130101) Original (OR) Class
H04S 2400/01 (20130101)
H04S 2400/13 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 11999853 Helgason et al.
FUNDED BY
Department of Veterans Affairs (DVA)
DVA Office of Research and Development (DVAORD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Non-Profit Organization (NPO)
Dystrophic Epidermolysis Bullosa Research Association of America (DEBRA of America)
APPLICANT(S) VitroLabs Inc (Milpitas, California);  King's College London (London, United Kingdom)
ASSIGNEE(S) VITROLABS INC (Milpitas, California);  KING'S COLLEGE LONDON (London, United Kingdom)
INVENTOR(S) Ingvar Helgason (South San Francisco, California);  Dusko Ilic (London, United Kingdom)
ABSTRACT Disclosed herein are synthetic leathers, artificial epidermal layers, artificial dermal layers, layered structures, products produced therefrom and methods of producing the same.
FILED Wednesday, July 05, 2023
APPL NO 18/347349
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compositions of Macromolecular Compounds
C08L 89/06 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0625 (20130101)
C12N 5/0629 (20130101)
C12N 5/0698 (20130101)
C12N 11/02 (20130101)
C12N 2501/155 (20130101)
C12N 2501/385 (20130101)
C12N 2502/13 (20130101)
C12N 2502/091 (20130101)
C12N 2502/094 (20130101)
C12N 2506/45 (20130101)
C12N 2533/30 (20130101)
C12N 2533/54 (20130101)

Chemical Treatment of Hides, Skins or Leather, e.g Tanning, Impregnating, Finishing; Apparatus Therefor; Compositions for Tanning
C14C 3/02 (20130101)
C14C 13/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12002150 Zhao et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
Office of Naval Research (ONR)
Non-Profit Organization (NPO)
Semiconductor Research Corporation (SRC)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Yajie Zhao (Los Angeles, California);  Jing Yang (Los Angeles, California);  Hanyuan Xiao (Los Angeles, California)
ABSTRACT Methods and systems are provided for rendering photo-realistic images of a subject or an object using a differentiable neural network for predicting indirect light behavior. In one example, the differentiable neural network outputs a volumetric light map comprising a plurality of spherical harmonic representations. Further, using a reflectance neural network, roughness and scattering coefficients associated with the subject or the object is computed. The volumetric light map, as well as the roughness and scattering coefficients are the utilized for rendering a final image under one or more of a desired lighting condition, desired camera view angle, and/or with a desired visual effect (e.g., expression change).
FILED Tuesday, May 03, 2022
APPL NO 17/735869
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Image Data Processing or Generation, in General
G06T 15/04 (20130101)
G06T 15/10 (20130101)
G06T 15/80 (20130101)
G06T 15/506 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 11998007 Kaeppler et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Systems (IOS)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Shawn Kaeppler (Middleton, Wisconsin);  Heidi Kaeppler (Middleton, Wisconsin);  Michael William Petersen (Merrimac, Wisconsin);  Brian Joseph Martinell (Mount Horeb, Wisconsin);  Frank McFarland (Middleton, Wisconsin)
ABSTRACT A maize pollen composition containing polyether ether ketone and pollen for collecting pollen and storing pollen.
FILED Monday, March 14, 2022
APPL NO 17/694200
ART UNIT 1661 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 5/10 (20130101)
A01H 6/4684 (20180501)

Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 3/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 11999650 Thostenson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Office of Polar Programs (OPP)
The Office of Polar Programs Antarctic (ANT)
Department of Transportation (USDOT)
Federal Highway Administration (FHWA)
National Highway Traffic Safety Administration (NHTSA)
APPLICANT(S) UNIVERSITY OF DELAWARE (Newark, Delaware)
ASSIGNEE(S)
INVENTOR(S) Erik Thostenson (Newark, Delaware);  Thomas Schumacher (Portland, Oregon)
ABSTRACT Processes for depositing functionalized nanoparticles upon a non-conductive substrate are disclosed herein. The processes may include the step of aerosolizing one or more particles into suspension within a gas, each of the one or more particles comprising functionalized nanoparticles having an electric charge. The processes may include the step the step of attracting the one or more particles onto a non-conductive substrate by a static electric charge opposite of the electric charge, wherein at least portions of the non-conductive substrate are having the static electric charge. The processes may include the step of depositing the functionalized nanoparticles onto the non-conductive substrate.
FILED Wednesday, November 09, 2022
APPL NO 17/983818
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials
C03C 25/44 (20130101) Original (OR) Class

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/041 (20170501)
C08K 3/042 (20170501)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 5/4419 (20130101)
C09D 7/61 (20180101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 13/02 (20130101)
C25D 13/12 (20130101)
C25D 13/22 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/254 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 12003411 Beecroft et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
National Security Agency (NSA)
Maryland Procurement Office (MPO)
APPLICANT(S) Hewlett Packard Enterprise Development LP (Houston, Texas)
ASSIGNEE(S) Hewlett Packard Enterprise Development LP (Spring, Texas)
INVENTOR(S) Jonathan P. Beecroft (Bristol, United Kingdom);  Edwin L. Froese (Burnaby, Canada)
ABSTRACT Systems and methods are provided for “on the fly” routing of data transmissions in the presence of errors. Switches can establish flow channels corresponding to flows in the network. In response to encountering a critical error on a network link along a transmission path, a switch can generate an error acknowledgement. The switch can transmit the error acknowledgements to ingress ports upstream from the network link via the plurality of flow channels. By transmitting the error acknowledgement, it indicates that the network link where the critical error was encountered is a failed link to ingress ports upstream from the failed link. Subsequently, each ingress port upstream from the failed link can dynamically update the path of the plurality of flows that are upstream from the failed link such that the plurality of flows that are upstream from the failed link are routed in a manner that avoids the failed link.
FILED Monday, March 23, 2020
APPL NO 17/594712
ART UNIT 2478 — Multiplex and VoIP
CURRENT CPC
Electric Digital Data Processing
G06F 9/505 (20130101)
G06F 9/546 (20130101)
G06F 12/0862 (20130101)
G06F 12/1036 (20130101)
G06F 12/1063 (20130101)
G06F 13/14 (20130101)
G06F 13/16 (20130101)
G06F 13/385 (20130101)
G06F 13/1642 (20130101)
G06F 13/1673 (20130101)
G06F 13/1689 (20130101)
G06F 13/4022 (20130101)
G06F 13/4068 (20130101)
G06F 13/4221 (20130101)
G06F 15/17331 (20130101)
G06F 2212/50 (20130101)
G06F 2213/0026 (20130101)
G06F 2213/3808 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 1/0083 (20130101)
H04L 43/10 (20130101)
H04L 43/0876 (20130101)
H04L 45/02 (20130101)
H04L 45/16 (20130101)
H04L 45/20 (20130101)
H04L 45/021 (20130101)
H04L 45/22 (20130101)
H04L 45/24 (20130101)
H04L 45/028 (20130101)
H04L 45/28 (20130101) Original (OR) Class
H04L 45/38 (20130101)
H04L 45/42 (20130101)
H04L 45/46 (20130101)
H04L 45/70 (20130101)
H04L 45/122 (20130101)
H04L 45/123 (20130101)
H04L 45/125 (20130101)
H04L 45/566 (20130101)
H04L 45/745 (20130101)
H04L 45/7453 (20130101)
H04L 47/11 (20130101)
H04L 47/12 (20130101)
H04L 47/18 (20130101)
H04L 47/20 (20130101)
H04L 47/22 (20130101)
H04L 47/24 (20130101)
H04L 47/30 (20130101)
H04L 47/32 (20130101)
H04L 47/34 (20130101)
H04L 47/39 (20130101)
H04L 47/52 (20130101)
H04L 47/76 (20130101)
H04L 47/80 (20130101)
H04L 47/122 (20130101)
H04L 47/323 (20130101)
H04L 47/621 (20130101)
H04L 47/626 (20130101)
H04L 47/629 (20130101)
H04L 47/762 (20130101)
H04L 47/781 (20130101)
H04L 47/2441 (20130101)
H04L 47/2466 (20130101)
H04L 47/2483 (20130101)
H04L 47/6235 (20130101)
H04L 47/6275 (20130101)
H04L 49/15 (20130101)
H04L 49/30 (20130101)
H04L 49/90 (20130101)
H04L 49/101 (20130101)
H04L 49/3009 (20130101)
H04L 49/3018 (20130101)
H04L 49/3027 (20130101)
H04L 49/9005 (20130101)
H04L 49/9021 (20130101)
H04L 49/9036 (20130101)
H04L 49/9047 (20130101)
H04L 67/1097 (20130101)
H04L 69/22 (20130101)
H04L 69/28 (20130101)
H04L 69/40 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 11998438 Sicotte et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ZENFLOW, INC. (San Francisco, California)
ASSIGNEE(S) ZENFLOW, INC. (San Francisco, California)
INVENTOR(S) Marcel Song Sicotte (San Francisco, California);  Austin Michael Bly (San Clemente, California);  Ben Collett-Nye (Kumeu, New Zealand);  Shreya Mehta (San Francisco, California)
ABSTRACT Systems, devices, and methods are provided for the delivery of an implant into the prostatic urethra. Embodiments of delivery systems can include a delivery device for insertion into the patient and a proximal control device for use in controlling release of the implant from the delivery device.
FILED Tuesday, July 20, 2021
APPL NO 17/380377
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/3468 (20130101)
A61B 2017/00274 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/042 (20130101) Original (OR) Class
A61F 2/885 (20130101)
A61F 2/966 (20130101)
A61F 2002/047 (20130101)
A61F 2250/001 (20130101)

Gearing
F16H 1/06 (20130101)
F16H 1/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, June 04, 2024.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240604.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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