FedInvent™ Patents
Patent Details for Tuesday, June 11, 2024
This page was updated on Tuesday, June 11, 2024 at 08:39 PM GMT
Department of Health and Human Services (HHS)
| US 12004493 | Yamada et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Hiroshi Yamada (Edmond, Oklahoma); Chinthalapally Rao (Oklahoma City, Oklahoma) |
| ABSTRACT | An animal model (e.g., mouse) and method of use, and cell culture assay method, for characterizing or screening a test compound for its effect on late onset Alzheimer's disease (LOAD). The test compound may be used as a therapeutic agent for treatment of Alzheimer's disease (AD). The AD animal model may be haploinsufficient for Shugoshin 1 (Sgo1) gene, or may comprise a genetic modification enabling modulation of Sgo1 expression in the brain of the animal when exposed to an Sgo1 expression-modulating compound, such as tamoxifen. After the test compound is administered to the animal model, the presence or amount of an AD biomarker is assessed or measured. |
| FILED | Monday, June 03, 2019 |
| APPL NO | 16/429978 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) Original (OR) Class A01K 2217/20 (20130101) A01K 2227/105 (20130101) A01K 2267/0312 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12004718 | Li |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The John Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Xingde Li (Ellicott City, Maryland) |
| ABSTRACT | The present invention is directed to an achromatic capsule endoscope with diffractive optics. A micromotor (or a broadband rotary joint) and a custom 800 nm SD-OCT system make ultrahigh-resolution 3D volumetric imaging over a large area possible. The diffractive microlens is used directly with other miniature lens including but not limited to a GRIN lens, making the capsule endoscope design simpler and cost effective. Preliminary ex vivo 3D intraluminal imaging was performed with the distal-scanning capsule endoscope in conjunction with a home-built broadband spectral-domain OCT system, demonstrating the performance of the diffractive capsule. Considering the miniature OCT capsule imaging probe is an attractive component for using the OCT technology for esophagus imaging (or other internal organs), the proposed approach will have a broad impact on endoscopic OCT imaging by improving OCT resolution in any applications that involve a capsule OCT probe, such as gastrointestinal (GI) tract imaging, airway imaging etc. |
| FILED | Friday, January 26, 2018 |
| APPL NO | 16/481248 |
| ART UNIT | 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/041 (20130101) Original (OR) Class A61B 1/00117 (20130101) A61B 1/00172 (20130101) A61B 1/00188 (20130101) A61B 5/0066 (20130101) Optical Elements, Systems, or Apparatus G02B 27/4227 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12004876 | Gao et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Wei Gao (Pasadena, California); You Yu (Pasadena, California) |
| ABSTRACT | An auto-powered biosensor capable detecting a target molecule, and a method of powering the same, wherein the biosensor is fabricated with a microfluidics layer, a multimodal sensing layer comprising a biofuel cell and an electrode, and a logic circuit that may include a processor and non-transitory memory with computer executable instructions embedded thereon. |
| FILED | Thursday, April 22, 2021 |
| APPL NO | 17/237925 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/0004 (20130101) A61B 5/1486 (20130101) A61B 5/6832 (20130101) Original (OR) Class A61B 5/14517 (20130101) A61B 10/007 (20130101) A61B 10/0051 (20130101) A61B 10/0064 (20130101) A61B 2010/0067 (20130101) A61B 2560/0214 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12004882 | Witschey et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Walter R. T. Witschey (Philadelphia, Pennsylvania); Francisco Contijoch (San Diego, California); Mark A. Elliott (Bryn Mawr, Pennsylvania); Eugene E. Gualtieri (Philadelphia, Pennsylvania) |
| ABSTRACT | An adaptive real-time radial k-space sampling trajectory (ARKS) can respond to a physiologic feedback signal to reduce motion effects and ensure sampling uniformity. In this adaptive k-space sampling strategy, the most recent signals from an ECG waveform can be continuously matched to the previous signal history, new radial k-space locations were determined, and these MR signals combined using multi-shot or single-shot radial acquisition schemes. The disclosed methods allow for improved MRI imaging. |
| FILED | Tuesday, October 27, 2015 |
| APPL NO | 15/522098 |
| ART UNIT | 3798 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/33 (20210101) A61B 5/0044 (20130101) A61B 5/055 (20130101) A61B 5/7289 (20130101) Original (OR) Class A61B 2576/023 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4824 (20130101) G01R 33/5673 (20130101) G01R 33/56325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12004998 | Keller |
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| FUNDED BY |
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| APPLICANT(S) | Centricity Vision, Inc. (Carlsbad, California) |
| ASSIGNEE(S) | Centricity Vision, Inc. (Carlsbad, California) |
| INVENTOR(S) | Christopher Guild Keller (El Cerrito, California) |
| ABSTRACT | A surgical device and procedure are provided for smoothly and easily accessing tissue to perform microsurgery, including a capsulotomy of a lens capsule of an eye. The device includes a handpiece with a tip for insertion into an incision in the cornea of the eye. A sliding element is disposed within the handpiece and a suction cup is mounted to the sliding element. The sliding element can be translated to move the suction cup into and out of the handpiece. A compression mechanism associated with the suction cup and the handpiece compresses the suction cup for deployment through the tip of the handpiece. The suction cup can expand inside the anterior chamber into a cutting position on the lens capsule. A cutting element mounted to the suction cup is used to cut a portion of the lens capsule and to remove the portion from the eye. The cutting element may be mounted to a cutting element support structure in a way that prevents heating of the device. |
| FILED | Tuesday, August 09, 2022 |
| APPL NO | 17/883993 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) A61B 18/1402 (20130101) A61B 2018/00291 (20130101) A61B 2018/00321 (20130101) A61B 2018/00601 (20130101) A61B 2018/1407 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0017 (20130101) A61F 9/00754 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12004999 | Keller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Centricity Vision, Inc. (Carlsbad, California) |
| ASSIGNEE(S) | Centricity Vision, Inc. (Carlsbad, California) |
| INVENTOR(S) | Christopher Guild Keller (El Cerrito, California); Thomas Haynes McGaffigan (Saratoga, California); Kevin L. Waltz (Indianapolis, Indiana); Thomas Milton McNicholas (Laguna Niguel, California) |
| ABSTRACT | Embodiments of the invention provide hydrodissection and/or PCO prevention or reduction in a patient undergoing eye surgery. In one embodiment, the invention is a surgical device for cutting and excising a portion of tissue, for example in performing a lens capsulotomy. A capsulotomy tip is inserted into an eye through an incision in the surface of the eye. The capsulotomy tip includes a suction cup to provide suction to the lens capsule. Then suction is applied via the suction cup to secure the capsulotomy tip to the eye. In some embodiments, after the capsulotomy tip is secured to the lens capsule, a cutting element of the capsulotomy tip is used to cut a tissue of the eye. Fluid is pushed through the capsulotomy tip and the capsulotomy tip is removed from the eye. Moreover, disclosed is an intraocular lens (IOL) to be used in conjunction with the surgical device. |
| FILED | Friday, February 03, 2023 |
| APPL NO | 18/164506 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/08 (20130101) A61B 2018/00291 (20130101) A61B 2018/00321 (20130101) A61B 2018/00601 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/16 (20130101) A61F 9/008 (20130101) A61F 9/00754 (20130101) Original (OR) Class A61F 2009/00889 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005039 | Goodyear et al. |
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| FUNDED BY |
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| APPLICANT(S) | Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Joslin Diabetes Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Laurie J. Goodyear (Southborough, Massachusetts); Kristin Stanford (Columbus, Ohio) |
| ABSTRACT | The invention includes methods and compositions for treating a metabolic disorder, such as metabolic syndrome, hyperlipidemia and associated disorders, such as obesity and diabetes. The invention includes a method of treating a human subject comprising administering 12,13-dihydroxy-9Z-octadecenoic acid (12,13-diHOME) to the subject. The invention also includes methods and compositions for treating disorders and conditions that would benefit from skeletal muscle fatty acid uptake and oxidation, increased mitochondrial respiration in skeletal muscle and/or enhanced exercise capacity. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/080528 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/201 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 21/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005046 | Wrobel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Biohaven Therapeutics Ltd. (New Haven, Connecticut) |
| ASSIGNEE(S) | Biohaven Therapeutics Ltd. (New Haven, Connecticut) |
| INVENTOR(S) | Jay Edward Wrobel (Lawrenceville, New Jersey); Allen B. Reitz (Lansdale, Pennsylvania); Jeffrey Claude Pelletier (Lafayette Hill, Pennsylvania); Garry Robert Smith (Royersford, Pennsylvania); Haiyan Bian (Princeton, New Jersey) |
| ABSTRACT | Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process. |
| FILED | Monday, February 01, 2021 |
| APPL NO | 17/164654 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 9/1617 (20130101) A61K 9/2004 (20130101) A61K 31/428 (20130101) Original (OR) Class A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/541 (20130101) A61K 31/5377 (20130101) A61K 38/05 (20130101) A61K 38/06 (20130101) A61K 39/4636 (20230501) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/28 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 277/82 (20130101) C07D 417/12 (20130101) Peptides C07K 5/0806 (20130101) C07K 5/0808 (20130101) C07K 5/0812 (20130101) C07K 5/06026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005047 | Wrobel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Biohaven Therapeutics Ltd. (New Haven, Connecticut) |
| ASSIGNEE(S) | Biohaven Therapeutics Ltd. (New Haven, Connecticut) |
| INVENTOR(S) | Jay Edward Wrobel (Lawrenceville, New Jersey); Allen B. Reitz (Lansdale, Pennsylvania); Jeffery Claude Pelletier (Lafayette Hill, Pennsylvania); Garry Robert Smith (Royersford, Pennsylvania); Haiyan Bian (Princeton, New Jersey) |
| ABSTRACT | Pharmaceutical compositions of the invention include substituted riluzole prodrugs useful for the treatment of cancers including melanoma, breast cancer, brain cancer, and prostate cancer through the release of riluzole. Prodrugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process. |
| FILED | Saturday, July 29, 2023 |
| APPL NO | 18/361837 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 9/1617 (20130101) A61K 9/2004 (20130101) A61K 31/428 (20130101) Original (OR) Class A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/541 (20130101) A61K 31/5377 (20130101) A61K 38/05 (20130101) A61K 38/06 (20130101) A61K 39/4636 (20230501) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/28 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 277/82 (20130101) C07D 417/12 (20130101) Peptides C07K 5/0806 (20130101) C07K 5/0808 (20130101) C07K 5/0812 (20130101) C07K 5/06026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005066 | Boss et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Gerard Boss (La Jolla, California); Adriano Chan (La Jolla, California); Matthew Brenner (La Jolla, California); Sari Brenner Mahon (La Jolla, California); Vikhyat Bebarta (Denver, Colorado) |
| ABSTRACT | Methods and compositions for treating cyanide, sulfide, or methane-thiol exposure in a subject. The compositions may include one or more cobinamide compounds, such as an amino-tetrazole-cobinamide and/or a di-(amino-tetrazole)-cobinamide. |
| FILED | Tuesday, June 04, 2019 |
| APPL NO | 15/734254 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/555 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005073 | Anderson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kenneth C. Anderson (Wellesley, Massachusetts); Yu-Tzu Tai (Newton, Massachusetts) |
| ABSTRACT | The present invention is based, in part, on methods for modulating regulatory T cells, regulatory B cells, and immune responses using modulators of the APRIL-TACI interaction. |
| FILED | Wednesday, June 20, 2018 |
| APPL NO | 16/612938 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/6803 (20170801) Peptides C07K 16/2875 (20130101) C07K 2317/24 (20130101) C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/20 (20170501) C12N 2310/141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005078 | Lamb et al. |
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| FUNDED BY |
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| APPLICANT(S) | The UAB Research Foundation (Birmingham, Alabama); Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama); Emory University (Atlanta, Georgia); Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Lawrence S. Lamb (Birmingham, Alabama); H. Trent Spencer (Marietta, Georgia); G. Yancey Gillespie (Birmingham, Alabama) |
| ABSTRACT | The present disclosure provides novel cell compositions engineered to express at least a chimeric antigen receptor and a survival factor. Methods of using such cell compositions are also described. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/756937 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) A61K 31/495 (20130101) A61K 35/17 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 39/00111 (20180801) A61K 39/00115 (20180801) A61K 39/00119 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) A61K 39/001109 (20180801) A61K 39/001112 (20180801) A61K 39/001113 (20180801) A61K 39/001119 (20180801) A61K 39/001122 (20180801) A61K 39/001124 (20180801) A61K 39/001126 (20180801) A61K 39/001129 (20180801) A61K 39/001151 (20180801) A61K 39/001164 (20180801) A61K 39/001166 (20180801) A61K 39/001168 (20180801) A61K 39/001171 (20180801) A61K 39/001174 (20180801) A61K 39/001181 (20180801) A61K 39/001182 (20180801) A61K 39/001188 (20180801) A61K 39/001189 (20180801) A61K 39/001193 (20180801) A61K 39/001195 (20180801) A61K 45/06 (20130101) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/7155 (20130101) C07K 16/30 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 5/0646 (20130101) C12N 9/12 (20130101) C12N 2501/72 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 207/10001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005079 | Garcia et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); University of Washington (Seattle, Washington) |
| INVENTOR(S) | Kenan Christopher Garcia (Menlo Park, California); Jonathan Sockolosky (San Francisco, California); Lora Picton (Foster City, California) |
| ABSTRACT | Engineered orthogonal cytokine receptor/ligand pairs, and methods of use thereof, are provided. |
| FILED | Thursday, November 19, 2020 |
| APPL NO | 16/953000 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/1793 (20130101) A61K 38/1793 (20130101) A61K 38/2013 (20130101) A61K 38/2013 (20130101) A61K 2039/5156 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) C12N 15/1034 (20130101) C12N 2740/10043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005089 | Ensign et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Laura Ensign (Towson, Maryland); Richard Cone (Baltimore, Maryland); Justin Hanes (Baltimore, Maryland) |
| ABSTRACT | Methods and materials for treating bacterial vaginosis (“BV”) are provided. Cervicovaginal secretions (“CVS”) from a woman with vaginal microbiota dominated (>50%) by one of the species of lactobacillus typically found in the human vagina, e.g. Lactobacillus crispatus, L. iners, L. gasseri, L jensenii, is transplanted to women with BV as a method for restoring beneficial vaginal microbial communities and/or increasing resistance to sexually transmitted disease. Efficacy can be enhanced, or the properties of the endogenous CVS improved, through administration of an acidifying agent such as lactic acid. The examples demonstrate the role of healthy CVS in disease resistance, and the effect of pH on CVS properties. The examples also describe the collection and transplantation of healthy beneficial CVS into women at risk for, or after treatment for, BV. |
| FILED | Monday, June 06, 2016 |
| APPL NO | 15/174540 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/00 (20130101) A61K 9/19 (20130101) A61K 9/0034 (20130101) A61K 9/0095 (20130101) A61K 35/747 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005103 | Davila et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND (Baltimore, Maryland) |
| INVENTOR(S) | Eduardo Davila (Cockeyville, Maryland); Koji Tamada (Ube, Japan) |
| ABSTRACT | The present invention provides a universal, yet adaptable, anti-tag chimeric antigen receptor (AT-CAR) system which provides T cells with the ability and specificity to recognize and kill target cells, such as tumor cells, that have been marked by tagged antibodies. As an example, αFITC-CAR-expressing T cells have been developed that specifically recognize various human cancer cells when those cells are bound by cancer-reactive FITC-labeled antibodies. The activation of αFITC-CAR-expressing T cells is shown to induce efficient target lysis, T cell proliferation, and cytokine/chemokine production. The system can be used to treating subjects having cancer. |
| FILED | Monday, April 12, 2021 |
| APPL NO | 17/228001 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/39558 (20130101) A61K 47/555 (20170801) A61K 47/6855 (20170801) A61K 47/6859 (20170801) A61K 47/6863 (20170801) A61K 47/6897 (20170801) A61K 2039/572 (20130101) A61K 2039/585 (20130101) A61K 2039/5156 (20130101) Peptides C07K 16/44 (20130101) C07K 16/2863 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2501/515 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005115 | Kanekiyo et al. |
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| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented By The Secretary of the Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | Masaru Kanekiyo (North Bethesda, Maryland); Gary J. Nabel (Chestnut Hill, Massachusetts); Jeffrey Cohen (Silver Springs, Maryland); Wei Bu (Potomac, Maryland) |
| ABSTRACT | Vaccines are provided that elicit neutralizing antibodies to Epstein-Barr virus (EBV). Some vaccines comprise nanoparticles that display envelope proteins from EBV on their surface. The nanoparticles comprise fusion proteins comprising a monomeric subunit of a self-assembly protein, such as ferritin, joined to at least a portion of an EBV envelope protein. The fusion proteins self-assemble to form the envelope protein-displaying nanoparticles. Such vaccines can be used to vaccinate an individual against infection by different types of Epstein-Barr viruses as well as Epstein-Barr viruses that are antigenically divergent from the virus from which the EBV envelope protein was obtained. Also provided are fusion proteins and nucleic acid molecules encoding such proteins. |
| FILED | Tuesday, July 07, 2020 |
| APPL NO | 16/922322 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 2039/64 (20130101) A61K 2039/575 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/00 (20130101) C07K 14/005 (20130101) C07K 14/195 (20130101) C07K 16/085 (20130101) C07K 2317/33 (20130101) C07K 2317/76 (20130101) C07K 2319/00 (20130101) C07K 2319/40 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16222 (20130101) C12N 2710/16234 (20130101) C12N 2710/16271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005121 | Quijano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Elias Quijano (Durham, Connecticut); Peter Glazer (Guilford, Connecticut) |
| ABSTRACT | Compositions and methods of use thereof for delivering nucleic acid cargo into cells are provided. The compositions typically include (a) a 3E10 monoclonal antibody or an antigen binding, cell-penetrating fragment thereof; a monovalent, divalent, or multivalent single chain variable fragment (scFv); or a diabody; or humanized form or variant thereof, and (b) a nucleic acid cargo including, for example, a nucleic acid encoding a polypeptide, a functional nucleic acid, a nucleic acid encoding a functional nucleic acid, or a combination thereof. Elements (a) and (b) are typically non-covalently linked to form a complex. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823492 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/549 (20170801) Original (OR) Class A61K 47/6807 (20170801) A61K 47/6851 (20170801) A61K 48/00 (20130101) A61K 48/005 (20130101) A61K 48/0025 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/52 (20130101) C07K 14/4747 (20130101) C07K 16/44 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/77 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/1135 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/3181 (20130101) C12N 2310/3513 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005128 | Cui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lina Cui (Gainesville, Florida); Jun Liu (Gainesville, Florida); Xiaowei Ma (Gainesville, Florida); Ying Wang (Albuquerque, New Mexico); Philip Deenik (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| INVENTOR(S) | Lina Cui (Gainesville, Florida); Jun Liu (Gainesville, Florida); Xiaowei Ma (Gainesville, Florida); Ying Wang (Albuquerque, New Mexico); Philip Deenik (Albuquerque, New Mexico) |
| ABSTRACT | A probe comprising a biomarker-triggered moiety, a near infrared (NIR) fluorophore reporter, a self-immolative linker and a self-immobilizing moiety for visualization of senescent cells and methods of use thereof. |
| FILED | Thursday, April 02, 2020 |
| APPL NO | 16/838907 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0043 (20130101) Original (OR) Class A61K 49/0058 (20130101) Heterocyclic Compounds C07D 491/052 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 2458/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005177 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Zhongjun Wu (Marriottsville, Maryland); Bartley P. Griffith (Gibson Island, Maryland); Keshava Rajagopal (Sugar Land, Texas) |
| ABSTRACT | The present invention discloses a self-sealing cannula and methods of its use. The self-sealing cannula can be minimally invasively placed into the heart for drawing and/or returning blood with a self-sealing function at the interface of the blood access site. The disclosed cannula can be implemented as a single lumen cannula or a double lumen cannula, which can be used with ventricular assist devices for heart support or pump-oxygenators for ECMO and respiratory support. Through a self-sealing mechanism fixed on the ventricular wall or atrial wall, a cannula body is attached to the self-sealing fixture and blood is drawn into the lumen via an external pump and returned to the circulation system through a separate cannula. In the case of the double lumen cannula embodiment, the blood will be drawn into the drainage lumen of the double lumen cannula and returned through an infusion lumen at the desired location. The present invention achieves minimally invasive insertion without surgical sutures to the heart, and allows for optimal drainage of the blood from the heart. With use of the double lumen cannula, it prevents need for multiple cannulation sites, and greatly reduces the blood recirculation. Removal of the cannula is simplified without need for suturing or insertion of a plugging member. |
| FILED | Wednesday, June 03, 2020 |
| APPL NO | 16/891655 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/3417 (20130101) A61B 17/3421 (20130101) A61B 17/3439 (20130101) A61B 2017/00247 (20130101) A61B 2017/3419 (20130101) A61B 2017/3425 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3659 (20140204) Original (OR) Class A61M 60/38 (20210101) A61M 60/148 (20210101) A61M 60/178 (20210101) A61M 60/857 (20210101) A61M 60/861 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005265 | Stanley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE ROCKEFELLER UNIVERSITY (New York, New York); RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | THE ROCKEFELLER UNIVERSITY (New York, New York); RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| INVENTOR(S) | Sarah Stanley (Berkeley, California); Jeffrey Friedman (New York, New York); Jonathan S. Dordick (Schenectady, New York); Jeremy Sauer (Princeton, New Jersey) |
| ABSTRACT | The present invention provides methods and compositions for the remote control of cell function based on the use of a magnetic field to excite paramagnetic nanoparticles targeted to specific cell types. The cell type of interest expresses an ion channel wherein excitation of the paramagnetic nanoparticles results in a physical change that is transduced into a cellular response. Such cellular responses may include, for example, increases in gene expression resulting in production of one or more physiologically active proteins. The expression of such proteins can be used to treat a variety of different inherited or acquired diseases or disorders in a subject. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 16/986482 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 47/6929 (20170801) A61K 48/00 (20130101) A61K 48/005 (20130101) A61K 48/0075 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2/00 (20130101) A61N 2/002 (20130101) Original (OR) Class A61N 2/004 (20130101) A61N 2/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/08 (20180101) Peptides C07K 14/705 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) C12N 15/86 (20130101) C12N 2710/10343 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005448 | Scarabelli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Leonardo Scarabelli (Los Angeles, California); Gail Vinnacombe (Los Angeles, California); Liv Heidenreich (Los Angeles, California); Naihao Chiang (Los Angeles, California); Yao Gong (Los Angeles, California); Paul S. Weiss (Los Angeles, California); Steven J. Jonas (Los Angeles, California) |
| ABSTRACT | Systems and methods are disclosed that utilize metal nanostructures that are synthesized in situ along the internal surfaces of a microfluidic device. The nanostructures are formed by initial deposition of metallic seeds followed by flowing growth and reducing agent solutions into the capillaries/microfluidic channels to grow the nanostars. The nanostructures may optionally be functionalized with a capture ligand. The capture ligand may be used to selectively bind to certain cells (e.g., circulating tumor cells). The cells may be removed by a beam of light (e.g., laser beam) that induces localized heating at the surface location(s) containing the nanostructures. The plasmonic nature of the nanostructures can be used to heat the nanostructure(s) locally for the selective removal of one or certain cells. The nanostructures may be used to acquire Raman spectra of molecules or other small objects that are bound thereto for identification and quantification. |
| FILED | Friday, August 16, 2019 |
| APPL NO | 17/268955 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 3/502761 (20130101) B01L 2300/0838 (20130101) B01L 2300/0896 (20130101) B01L 2400/0478 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 7/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/03 (20130101) C01P 2004/30 (20130101) C01P 2004/64 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) G01N 21/6458 (20130101) G01N 33/54346 (20130101) G01N 33/57492 (20130101) G01N 2021/656 (20130101) Optical Elements, Systems, or Apparatus G02B 21/006 (20130101) G02B 21/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005449 | Delmenico et al. |
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| FUNDED BY |
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| APPLICANT(S) | Haemonetics Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter Delmenico (Melbourne, Australia); Carlos G. Lopez-Espina (Evanston, Illinois); Gabriel Raviv (Glenview, Illinois) |
| ABSTRACT | A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/855634 |
| ART UNIT | 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/50273 (20130101) Original (OR) Class B01L 3/502753 (20130101) B01L 2300/165 (20130101) B01L 2300/0663 (20130101) B01L 2300/0816 (20130101) B01L 2300/0877 (20130101) B01L 2400/0433 (20130101) B01L 2400/0481 (20130101) B01L 2400/0487 (20130101) B01L 2400/0638 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 11/16 (20130101) G01N 29/032 (20130101) G01N 29/036 (20130101) G01N 29/2418 (20130101) G01N 33/4905 (20130101) G01N 2291/0251 (20130101) G01N 2291/0427 (20130101) G01N 2291/02466 (20130101) G01N 2291/02818 (20130101) G01N 2291/02827 (20130101) G01N 2800/224 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005452 | Kelly et al. |
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| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| INVENTOR(S) | Ryan T. Kelly (West Richland, Washington); Ying Zhu (Richland, Washington); Richard D. Smith (Richland, Washington) |
| ABSTRACT | Provided herein are methods and systems for biochemical analysis, including compositions and methods for processing and analysis of small cell populations and biological samples (e.g., a robotically controlled chip-based nanodroplet platform). In particular aspects, the methods described herein can reduce total processing volumes from conventional volumes to nanoliter volumes within a single reactor vessel (e.g., within a single droplet reactor) while minimizing losses, such as due to sample evaporation. |
| FILED | Tuesday, August 17, 2021 |
| APPL NO | 17/404478 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/00317 (20130101) B01J 2219/00367 (20130101) B01J 2219/00619 (20130101) B01J 2219/00621 (20130101) B01J 2219/00659 (20130101) B01J 2219/00702 (20130101) B01J 2219/00725 (20130101) B01J 2219/00743 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/00 (20130101) B01L 3/5088 (20130101) B01L 3/50853 (20130101) B01L 3/502753 (20130101) Original (OR) Class B01L 2200/142 (20130101) B01L 2300/0819 (20130101) B01L 2300/0822 (20130101) B01L 2300/0887 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/58 (20130101) C12M 41/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 60/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 1/34 (20130101) G01N 1/2813 (20130101) G01N 30/88 (20130101) G01N 33/68 (20130101) G01N 33/4833 (20130101) G01N 2001/284 (20130101) G01N 2030/8831 (20130101) Optical Elements, Systems, or Apparatus G02B 21/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006126 | Davidowitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | BioTillion, LLC (Skillman, New Jersey) |
| ASSIGNEE(S) | Bio Tillion, LLC (Skillman, New Jersey) |
| INVENTOR(S) | Hananel Davidowitz (Princeton, New Jersey); Theodore N. Altman (East Windsor, New Jersey); Ke Wang (Flemington, New Jersey); Zhengyan Zhai (Doylestown, Pennsylvania); Jeremy Basch (Middlesex, New Jersey); Ron Or (Moshav Bney Atarot, Israel) |
| ABSTRACT | A technique for tracking, for example, the temperature of one or more sample vials containing biological material stored in a low-temperature shipping vessel. Each sample vial has vial electronics that senses temperature and transmits temperature data to the reader head of a reader device, which has a controller that is not at the low temperature. In some implementations, the shipping vessel has a cap with a recess that houses the controller and a hollow plug that houses a cable that connects the controller to the reader head that is located in the vessel's cold interior sufficiently close to the sample vial to enable interaction with the vial electronics. In some implementations, the reader head transmits electrical power to the vial electronics. By tracking the temperature of individual sample vials rather than the temperature of the vessel interior, more-relevant temperature data is available. |
| FILED | Thursday, September 03, 2020 |
| APPL NO | 17/011518 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/1412 (20130101) A61J 2200/44 (20130101) A61J 2200/50 (20130101) A61J 2200/72 (20130101) A61J 2205/60 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 81/3825 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006294 | More et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Swati S. More (Minneapolis, Minnesota); Robert Vince (Minneapolis, Minnesota) |
| ABSTRACT | The invention provides methods for producing analgesia in an animal comprising administering to the animal a compound of the formula Ia′, Ib′, Ic′, and Id′: and pharmaceutically acceptable salts thereof, wherein the variables A, R6, R7, R8, R9, Rx, L, X, Y, and Z have the meaning as described herein. |
| FILED | Monday, June 03, 2019 |
| APPL NO | 16/429507 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 5/48 (20180101) A61P 25/16 (20180101) A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 279/06 (20130101) C07C 279/08 (20130101) C07C 279/18 (20130101) C07C 279/22 (20130101) C07C 281/14 (20130101) C07C 281/16 (20130101) C07C 281/18 (20130101) C07C 335/04 (20130101) C07C 335/12 (20130101) C07C 335/40 (20130101) Heterocyclic Compounds C07D 213/61 (20130101) C07D 231/38 (20130101) C07D 233/44 (20130101) Original (OR) Class C07D 233/50 (20130101) C07D 233/52 (20130101) C07D 233/64 (20130101) C07D 239/06 (20130101) C07D 239/18 (20130101) C07D 239/22 (20130101) C07D 239/47 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006301 | Ablordeppey |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida A and M University (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida A and M University (Tallahassee, Florida) |
| INVENTOR(S) | Seth Y. Ablordeppey (Tallahassee, Florida) |
| ABSTRACT | Novel dual 5-HT1A and 5-HT7 receptor ligands and methods of using the novel ligands to treat a neurological disorder are presented. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 17/732018 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 401/04 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 401/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006328 | Traynelis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Stephen F. Traynelis (Decatur, Georgia); Lanny S. Liebeskind (Atlanta, Georgia); Dennis C. Liotta (Atlanta, Georgia); Ethel C. Garnier-Amblard (Tucker, Georgia); PavanKumar Reddy Gangireddy (Atlanta, Georgia) |
| ABSTRACT | The disclosure relates thieno[2,3-d]pyrimidin-4-one derivatives as modulators of NMDA receptors and uses related thereto. In certain embodiments, the disclosure relates to pharmaceutical compositions comprising compounds disclosed herein or pharmaceutically acceptable salts or prodrugs thereof. In certain embodiments, the compositions disclosed herein are used for managing conditions related to cognition, typically prevention or treatment of neurological conditions related to the NMDA receptor. |
| FILED | Wednesday, November 18, 2015 |
| APPL NO | 15/528087 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/18 (20180101) A61P 25/22 (20180101) A61P 25/28 (20180101) Heterocyclic Compounds C07D 495/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006337 | Holtzman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| INVENTOR(S) | Michael J. Holtzman (St. Louis, Missouri); Arthur G. Romero (Chesterfield, Missouri); Benjamin J. Gerovac (St. Louis, Missouri); Zhenfu Han (St. Louis, Missouri); Shamus P. Keeler (University City, Missouri); Kangyun Wu (St. Louis, Missouri); Yong Zhang (St. Louis, Missouri) |
| ABSTRACT | Compounds that inhibit mitogen-activated protein kinases (MAPKs) are disclosed. Some inhibitor compounds specifically target a single MAPK such as MAPK13, while others target multiple MAPKs such as MAPK13 and MAPK12. The compounds can be used therapeutically for a variety of diseases, including cancer and respiratory diseases. Methods of synthesis of the compounds are also disclosed. |
| FILED | Wednesday, July 13, 2022 |
| APPL NO | 17/863657 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 213/75 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0812 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006347 | Garcia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Kenan Christopher Garcia (Menlo Park, California); Aron Levin (New York City, New York); Aaron Ring (Menlo Park, California) |
| ABSTRACT | Novel human interleukin-2 (IL-2) muteins or variants thereof, and nucleic acid molecules and variants thereof are provided. Methods for producing these muteins as well as methods for stimulating the immune system of an animal are also disclosed. In addition, the invention provides recombinant expression vectors comprising the nucleic acid molecules of this invention and host cells into which expression vectors have been introduced. Pharmaceutical compositions are included comprising a therapeutically effective amount of a human IL-2 mutein of the invention and a pharmaceutically acceptable carrier. The IL-2 muteins can be used in pharmaceutical compositions for use in treatment of cancer and in stimulating the immune response. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470246 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/55 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006355 | Hammock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Bruce D. Hammock (Davis, California); Natalia Vasylieva (Davis, California); Jiexian Dong (Davis, California); Christophe Morisseau (West Sacramento, California); Dean R. Madden (Hanover, New Hampshire) |
| ABSTRACT | Provided are VHH or nanobodies that specifically bind to cystic fibrosis transmembrane conductance regulator (CFTR) inhibitory factor (Cif), and uses thereof for diagnosis and treatment of Pseudomonas infection. |
| FILED | Tuesday, December 07, 2021 |
| APPL NO | 17/544377 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/40 (20130101) C07K 16/1214 (20130101) Original (OR) Class C07K 2317/22 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/569 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2333/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006366 | Leon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Provention Bio, Inc. (Red Bank, New Jersey) |
| ASSIGNEE(S) | Provention Bio, Inc. (, None); Yale University (, None); Benaroya Research Institure at Virginia Mason (, None) |
| INVENTOR(S) | Francisco Leon (Bethesda, Maryland); Kevan C. Herold (Norwalk, Connecticut); Sarah Alice Long (Seattle, Washington); Peter S. Linsley (Seattle, Washington) |
| ABSTRACT | Provided herein, in one aspect, is a method of preventing or delaying the onset of clinical type 1 diabetes (T1D), comprising: providing a non-diabetic subject who is at risk for T1D; administering a prophylactically effective amount of an anti-CD3 antibody to the non-diabetic subject; and determining, prior to or after the administering step, that the non-diabetic subject has more than about 5% to more than about 10% TIGIT+KLRG1+CD8+ T-cells in all CD3+ T cells, which is indicative of successful prevention or delay of the onset of clinical T1D. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 17/345495 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Peptides C07K 16/2809 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006404 | Portela et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Carlos M. Portela (Pasadena, California); Daryl Wei Liang Yee (Pasadena, California); Dennis M. Kochmann (Pasadena, California); Julia R. Greer (Pasadena, California) |
| ABSTRACT | In an aspect, provided herein are low density materials, including shell-based materials, with three-dimensional architectures formed, in part, via self-assembly processes. Shell-based materials of some embodiments exhibit a combination of ultralow density (e.g., ≤100 mg cm−3 and optionally ≤10 100 mg cm−3) and non-periodic architectures characterized by low defect densities and geometries avoiding stress concentrations. Low density shell based materials of some embodiments have architectures characterized by small curvatures and lack of straight edges providing enhance mechanical response. In some embodiments, for example, the present low density materials, including shell-based materials, providing a combination target mechanical properties including high stiffness-to-density ratios, mechanical resilience and tolerance for deformation. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/032539 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 38/0051 (20130101) C04B 38/0067 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/02 (20130101) Original (OR) Class C08J 9/26 (20130101) C08J 2363/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/45525 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249953 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006496 | Marshall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purigen Biosystems, Inc. (Pleasanton, California) |
| ASSIGNEE(S) | Purigen Biosystems, Inc. (Pleasanton, California) |
| INVENTOR(S) | Lewis A. Marshall (Pleasanton, California); Amy L. Hiddessen (Pleasanton, California); Nathan P. Hoverter (Pleasanton, California); Klint A. Rose (Pleasanton, California); Juan G. Santiago (Pleasanton, California) |
| ABSTRACT | The present disclosure relates to fluidic systems and devices for processing, extracting, or purifying one or more analytes. These systems and devices can be used for processing samples and extracting nucleic acids, for example by isotachophoresis. In particular, the systems and related methods can allow for extraction of nucleic acids, including non-crosslinked nucleic acids, from samples such as tissue or cells. The systems and devices can also be used for multiplex parallel sample processing. |
| FILED | Monday, May 01, 2023 |
| APPL NO | 18/141641 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502738 (20130101) B01L 3/502753 (20130101) B01L 2300/0627 (20130101) B01L 2300/0867 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 1/004 (20130101) B81B 7/0087 (20130101) B81B 2201/05 (20130101) B81B 2201/0278 (20130101) B81B 2203/0338 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) C12N 15/101 (20130101) Original (OR) Class C12N 15/101 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 2565/125 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4473 (20130101) G01N 27/44704 (20130101) G01N 27/44739 (20130101) G01N 27/44791 (20130101) G01N 27/44795 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006503 | Iavarone et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Antonio Iavarone (New York, New York); Anna Lasorella (New York, New York) |
| ABSTRACT | The invention discloses oncogenic fusion proteins. The invention provides methods for treating gene-fusion based cancers. |
| FILED | Thursday, June 11, 2020 |
| APPL NO | 16/899312 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/47 (20130101) C07K 14/71 (20130101) C07K 14/82 (20130101) C07K 16/18 (20130101) C07K 16/2863 (20130101) C07K 2319/00 (20130101) C07K 2319/73 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) C12N 15/62 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/91205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006520 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); John Paul Guilinger (Cambridge, Massachusetts); Vikram Pattanayak (Cambridge, Massachusetts) |
| ABSTRACT | Engineered nucleases are promising tools for genome manipulation and determining off-target cleavage sites of these enzymes is of great interest. This disclosure provides in vitro selection methods that interrogate 1011 DNA sequences for their ability to be cleaved by active nucleases, e.g., ZFNs and TALENs. The method revealed hundreds of thousands of DNA sequences that can be cleaved in vitro by two ZFNs, CCR5-224 and VF2468, which target the endogenous human CCR5 and VEGF-A genes, respectively. Analysis of the identified sites in cultured human cells revealed CCR5-224-induced mutagenesis at nine off-target loci. This disclosure provides an energy compensation model of ZFN specificity in which excess binding energy contributes to off-target ZFN cleavage. It was also observed that TALENs can achieve cleavage specificity similar to or higher than that observed in ZFNs. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/441751 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) C12Q 1/68 (20130101) C12Q 1/68 (20130101) C12Q 1/6874 (20130101) C12Q 2521/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006532 | Kennedy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Scott R. Kennedy (Seattle, Washington); Jesse J. Salk (Seattle, Washington); Michael Hipp (Seattle, Washington); Elizabeth Schmidt (Seattle, Washington); Rosa Ana Risques (Seattle, Washington); Daniela Nachmanson (Seattle, Washington) |
| ABSTRACT | The present technology relates generally to methods and compositions for targeted nucleic acid sequence enrichment, as well as uses of such enrichment for error-corrected nucleic acid sequencing applications. In some embodiments, highly accurate, error corrected and massively parallel sequencing of nucleic acid material is possible using a combination of uniquely labeled strands in a double-stranded nucleic acid complex in such a way that each strand can be informatically related to its complementary strand, but also distinguished from it following sequencing of each strand or an amplified product derived therefrom. In various embodiments, this information can be used for the purpose of error correction of the determined sequence. |
| FILED | Friday, September 16, 2022 |
| APPL NO | 17/933058 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) C12Q 2521/501 (20130101) C12Q 2525/191 (20130101) C12Q 2531/113 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006540 | Ju et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Jingyue Ju (Englewood Cliffs, New Jersey); Xiaoxu Li (New York, New York); Xin Chen (New York, New York); Zengmin Li (Flushing, New York); Shiv Kumar (Belle Meade, New Jersey); Shundi Shi (Ozone Park, New York); Cheng Guo (Brooklyn, New York); Jianyi Ren (New York, New York); Min-Kang Hsieh (New York, New York); Minchen Chien (Tenafly, New Jersey); Chuanjuan Tao (Fort Lee, New Jersey); Ece Erturk (New York, New York); Sergey Kalachikov (Bronx, New York); James J. Russo (New York, New York) |
| ABSTRACT | Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid. |
| FILED | Monday, August 01, 2022 |
| APPL NO | 17/816555 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) C07H 19/14 (20130101) C07H 19/20 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2525/117 (20130101) C12Q 2563/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006542 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Shoujun Xu (Houston, Texas); Qiongzheng Hu (Houston, Texas); Yuhong Wang (Houston, Texas) |
| ABSTRACT | Embodiments of the present disclosure pertain to methods of utilizing force-modulated hybridization to determine the length of an analyte strand, to determine an unknown nucleic acid sequence, or to determine the binding of a nucleotide to an active agent. Additional embodiments of the present disclosure pertain to sample holder devices and methods of utilizing such devices. Further embodiments of the present disclosure pertain to detection devices. |
| FILED | Monday, June 11, 2018 |
| APPL NO | 16/620571 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 7/52 (20130101) B01L 2200/0663 (20130101) B01L 2300/18 (20130101) B01L 2300/044 (20130101) B01L 2300/0654 (20130101) B01L 2300/0672 (20130101) B01L 2400/0439 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6818 (20130101) C12Q 1/6874 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006544 | Vogelstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Frankford, Delaware); Nickolas Papadopoulos (Towson, Maryland); Isaac A. Kinde (Beaumont, California) |
| ABSTRACT | The identification of mutations that are present in a small fraction of DNA templates is essential for progress in several areas of biomedical research. Though massively parallel sequencing instruments are in principle well-suited to this task, the error rates in such instruments are generally too high to allow confident identification of rare variants. We here describe an approach that can substantially increase the sensitivity of massively parallel sequencing instruments for this purpose. One example of this approach, called “Safe-SeqS” for (Safe-Sequencing System) includes (i) assignment of a unique identifier (UID) to each template molecule; (ii) amplification of each uniquely tagged template molecule to create UID-families; and (iii) redundant sequencing of the amplification products. PCR fragments with the same UID are truly mutant (“super-mutants”) if ≥95% of them contain the identical mutation. We illustrate the utility of this approach for determining the fidelity of a polymerase, the accuracy of oligonucleotides synthesized in vitro, and the prevalence of mutations in the nuclear and mitochondrial genomes of normal cells. |
| FILED | Monday, November 27, 2023 |
| APPL NO | 18/519727 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 1/6876 (20130101) C12Q 2525/179 (20130101) C12Q 2525/191 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006545 | Salk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
| ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/392180 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006549 | Weinand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Martin E. Weinand (Tucson, Arizona); Ryan Sprissler (Tucson, Arizona); Michael F. Hammer (Tucson, Arizona) |
| ABSTRACT | Methods involving analysis of pretreatment leukocyte expression profiles for prognostic assessment of seizure outcome following a treatment or medical procedure, such as stereotactic laser amygdalohippocampotomy (SLAH). In one aspect, RNA sequencing (RNA-Seq) on whole blood leukocyte samples is taken from a patient with intractable epilepsy prior to SLAH. Differential expression (DE) analysis revealed 24 significantly dysregulated genes (≥2.0-fold change, p-value <0.05, and False Discovery Rate, FDR <0.05) useful in prognostic assessment. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/269092 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/52 (20130101) G01N 2800/2857 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006550 | Tan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Wenbin Tan (Columbia, South Carolina); Elaine G. Taine (Columbia, South Carolina); Hui Wang (Wuhan, China PRC); Vi Nguyen (Columbia, South Carolina); Xiaoling Cao (Columbia, South Carolina) |
| ABSTRACT | Described herein are methods and systems using ADAM30 as a biomarker to help early diagnosis of congenital malformed vasculatures in children and which can also serve as a companion diagnostic biomarker for malformed vasculatures, as well as a subpopulation of cancer cells, wherein blockage of activity of ADAM30 by a neutralized antibody or inhibitor can be used as a treatment strategy for those ADAM30-positive vascular endothelial cells and cancer cells. |
| FILED | Thursday, August 12, 2021 |
| APPL NO | 17/400308 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/2896 (20130101) C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006555 | Bell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (, None); Dana-Farber Cancer Institute, Inc. (, None) |
| INVENTOR(S) | Daphne Winifred Bell (Kensington, Maryland); Daniel A. Haber (Chesnut Hill, Massachusetts); Pasi Antero Janne (Newton, Massachusetts); Bruce E. Johnson (Brookline, Massachusetts); Thomas J. Lynch (Newton, Massachusetts); Matthew Meyerson (Concord, Massachusetts); Juan Guillermo Paez (Dean Funes, Argentina); William R. Sellers (Chestnut Hill, Massachusetts); Jeffrey E. Settleman (Newton, Massachusetts); Raffaella Sordella (Bedford, Massachusetts) |
| ABSTRACT | Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug. |
| FILED | Tuesday, April 21, 2020 |
| APPL NO | 16/854654 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 33/574 (20130101) G01N 2333/485 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007316 | Enten et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Aaron C. Enten (Atlanta, Georgia); Todd Sulchek (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present disclosure relate generally to dead-end filtration systems and, more particularly, to pulse-modulated periodic backflush systems and methods for clearing fouling layers in dead-end filtration systems. In some embodiments, a controller may control the flow of fluid in the system from cycling from a forward flow to a reverse flow. In some embodiments, the controller may cycle from forward to reverse flow based on a volumetric flow ratio. Embodiments of the present disclosure describe optimal volumetric flow ratios for optimizing the break of cake in a dead-end filtration system. Embodiments of the present disclosure describe optimal volumetric flow ratios for optimizing recovery percentages of targeted particles. |
| FILED | Wednesday, January 30, 2019 |
| APPL NO | 16/965111 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/18 (20130101) B01D 61/22 (20130101) B01D 63/087 (20130101) B01D 2311/16 (20130101) B01D 2315/08 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 33/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) Original (OR) Class G01N 1/4005 (20130101) G01N 2001/4088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007354 | Burch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kenneth S. Burch (Brighton, Massachusetts); Tim van Opijnen (Somerville, Massachusetts); Jianmin Gao (Newton, Massachusetts); Narendra Kumar (Brighton, Massachusetts); Juan C. Ortiz-Marquez (Brighton, Massachusetts); Wenjian Wang (Brighton, Massachusetts); Mason Gray (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Kenneth S. Burch (Brighton, Massachusetts); Tim van Opijnen (Somerville, Massachusetts); Jianmin Gao (Newton, Massachusetts); Narendra Kumar (Brighton, Massachusetts); Juan C. Ortiz-Marquez (Brighton, Massachusetts); Wenjian Wang (Brighton, Massachusetts); Mason Gray (Chestnut Hill, Massachusetts) |
| ABSTRACT | A method and system for label-free detection of pathogenic and antibiotic resistant bacteria is disclosed. The method includes fabricating a G-FET/peptide device having a synthesized peptide probe capable of recognizing and binding to a bacterial target; performing electric-field assisted binding of at least one bacterial cell of the bacterial target to the G-FET/peptide device; and electrically detecting the binding of the at least one bacterial cell to the G-FET/peptide device. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/090982 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) Original (OR) Class G01N 27/4146 (20130101) G01N 27/4148 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007376 | Lebedev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trace-Ability, Inc. (Van Nuys, California) |
| ASSIGNEE(S) | Trace-Ability, Inc. (Van Nuys, California) |
| INVENTOR(S) | Artem Y. Lebedev (Santa Monica, California); Arkadij M. Elizarov (Woodland Hills, California) |
| ABSTRACT | A method for determining a concentration of a synthesis component in a radiopharmaceutical sample comprises providing an indicator, a metal or a metal complex, contacting the radiopharmaceutical sample with the indicator, metal or metal complex for a period of time sufficient to obtain an interaction, measuring an optical characteristic of the interacted components, and determining a concentration of the synthesis component in the radiopharmaceutical sample based on the measured optical characteristic. |
| FILED | Tuesday, December 15, 2020 |
| APPL NO | 17/122496 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) Apparatus for Enzymology or Microbiology; C12M 41/36 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/51 (20130101) G01N 21/78 (20130101) G01N 21/82 (20130101) G01N 21/253 (20130101) G01N 33/15 (20130101) Original (OR) Class G01N 2021/752 (20130101) G01N 2033/0093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007383 | Everson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Gregory Thomas Everson (Englewood, Colorado); Steve Mark Helmke (Denver, Colorado) |
| ABSTRACT | A method for estimating portal blood flow and hepatic function in a subject is provided. In one example, the STAT test is an in vitro simplified, convenient test intended for screening purposes that can reasonably estimate the portal blood flow from a single blood sample taken 60 minutes after orally administered deuterated-cholate. The test can be administered to a patient having, or suspected of having, Chronic Hepatitis C, Primary Sclerosing Cholangitis (PSC), Non-Alcoholic Fatty Liver Disease (NAFLD), or any chronic liver disease. |
| FILED | Tuesday, May 19, 2020 |
| APPL NO | 16/878510 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/05 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/49 (20130101) Original (OR) Class G01N 33/92 (20130101) G01N 2800/085 (20130101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007389 | Takulapalli |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | iNanoBio Inc. (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bharath Takulapalli (Scottsdale, Arizona) |
| ABSTRACT | The present disclosure provides an improved field effect transistor and device that can be used to sense and characterize a variety of materials. The field effect transistor and/or device including the transistor may be used for a variety of applications, including genome sequencing, protein sequencing, biomolecular sequencing, and detection of ions, molecules, chemicals, biomolecules, metal atoms, polymers, nanoparticles and the like. |
| FILED | Friday, April 15, 2022 |
| APPL NO | 17/722010 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/414 (20130101) G01N 27/4145 (20130101) G01N 27/4146 (20130101) G01N 33/552 (20130101) G01N 33/48721 (20130101) G01N 33/54366 (20130101) G01N 33/54373 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/30604 (20130101) H01L 29/0665 (20130101) H01L 29/0692 (20130101) H01L 29/1054 (20130101) H01L 29/66666 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007395 | Van Eyk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Jennifer E. Van Eyk (Baltimore, Maryland); Allen Dale Everett (Baltimore, Maryland); Zhicheng Jin (Baltimore, Maryland) |
| ABSTRACT | The present invention relates to the field of biomarkers. More specifically, the present invention relates to biomarkers useful in diagnosing brain injury or neurodegeneration. In one embodiment, a method for diagnosing brain injury in a patient comprises the steps of (a) obtaining a sample from the patient; (b) determining the ratio of citrullinated to unmodified arginine residues at one or more arginine residues of one or more brain injury biomarker proteins; and (c) correlating the ratio to a patient having brain injury or to a patient not having brain injury, thereby providing the diagnosis. |
| FILED | Thursday, June 06, 2019 |
| APPL NO | 16/433106 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5306 (20130101) G01N 33/6842 (20130101) G01N 33/6848 (20130101) Original (OR) Class G01N 2440/18 (20130101) G01N 2800/28 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0027 (20130101) H01J 49/0077 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008736 | Rahimi Nasrabadi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Albany, New York) |
| INVENTOR(S) | Hamed Rahimi Nasrabadi (Brooklyn, New York); José-Manuel Alonso (New York, New York) |
| ABSTRACT | Images may be altered based on ON-OFF visual pathway information processing. A process for generating altered images may include separating an original image into distinct images based on luminance values for each pixel of the pixels that form the original image. The distinct images may include a first and a second separated image, where each separated image includes distinct pixels. Additionally, the process may include determining a first luminance range for the first separated image based on the luminance value for each pixel forming the first separated image, and determining a second luminance range for the second separated image based on the luminance value for each pixel forming the second separated image. The process may also include adjusting visual parameters of the first and second separated images, and combining the adjusted, first and second separated images to generate the altered image. |
| FILED | Monday, December 20, 2021 |
| APPL NO | 17/556921 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) Original (OR) Class G06T 7/90 (20170101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10116 (20130101) G06T 2207/10132 (20130101) G06T 2207/20212 (20130101) Image or Video Recognition or Understanding G06V 10/56 (20220101) G06V 10/60 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008747 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Hersh Bhargava (San Francisco, California); Patrick Leo (Honeoye Falls, New York); Priti Lal (Ellicott City, Maryland) |
| ABSTRACT | Embodiments discussed herein facilitate determination of one of a probability of prostate cancer recurrence-free survival or a risk factor associated with prostate cancer based on intra-tumor stromal morphology. Example embodiments can perform operations comprising: accessing a digitized histological image of a prostate of a patient, wherein the histological image comprises a region of interest associated with prostate cancer; identifying nuclei of intra-tumoral stromal cells within the region of interest; extracting, for the region of interest of the digitized histological image, one or more features describing the structure of the intra-tumoral stromal cells; and generating, via a model based at least on the one or more features, one of a probability of prostate cancer recurrence-free survival or a risk score associated with prostate cancer for the patient based at least on the extracted one or more features. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/886966 |
| ART UNIT | 2699 — Search and Capture Special Detail |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30081 (20130101) Image or Video Recognition or Understanding G06V 10/7796 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008751 | Buckler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| INVENTOR(S) | Andrew J. Buckler (Boston, Massachusetts); Mark A. Buckler (Wenham, Massachusetts) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Friday, May 07, 2021 |
| APPL NO | 17/314766 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008764 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ALLEN INSTITUTE (Seattle, Washington) |
| ASSIGNEE(S) | ALLEN INSTITUTE (Seattle, Washington) |
| INVENTOR(S) | Gregory Johnson (Seattle, Washington); Chawin Ounkomol (Seattle, Washington); Forrest Collman (Seattle, Washington); Sharmishtaa Seshamani (Seattle, Washington) |
| ABSTRACT | A computing device, method, system, and instructions in a non-transitory computer-readable medium for performing image analysis on 3D microscopy images to predict localization and/or labeling of various structures or objects of interest, by predicting the location in such images at which a dye or other marker associated with such structures would appear. The computing device, method, and system receives sets of 3D images that include unlabeled images, such as transmitted light images or electron microscope images, and labeled images, such as images captured with fluorescence tagging. The computing device trains a statistical model to associate structures in the labeled images with the same structures in the unlabeled light images. The processor further applies the statistical model to a new unlabeled image to generate a predictive labeled image that predicts the location of a structure of interest in the new image. |
| FILED | Thursday, February 16, 2023 |
| APPL NO | 18/170076 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/045 (20230101) G06N 20/20 (20190101) Image Data Processing or Generation, in General G06T 7/11 (20170101) Original (OR) Class G06T 7/174 (20170101) G06T 7/187 (20170101) G06T 2207/10061 (20130101) G06T 2207/10064 (20130101) G06T 2207/30024 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/50 (20220101) G06V 10/764 (20220101) G06V 20/695 (20220101) G06V 20/698 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008987 | Stavisky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Sergey Stavisky (Davis, California); Krishna V. Shenoy (Palo Alto, California); Jaimie M. Henderson (Redwood City, California) |
| ABSTRACT | Systems and methods for decoding indented speech from neuronal activity in accordance with embodiments of the invention are illustrated. One embodiment includes a neuronal speech system for decoding intended speech from neuronal signals includes a neuronal signal recorder implanted into a user's brain, including a multielectrode array, controller circuitry, and a communication circuitry capable of transmitting data to a neuronal signal decoder, the neuronal signal decoder located externally from the user's body, including a processor, an input/output interface, and a memory, where the memory contains a neuronal speech application that directs the processor to obtain neuronal signal data from the neuronal signal recorder, where the neuronal signal data describes neuronal activity proximal to the implanted neuronal signal recorder, decode speech features from the neuronal signal data using a neuronal decoding model, construct a speech string from the decoded speech features; and output the constructed speech string via an output device. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 16/399412 |
| ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 5/0031 (20130101) A61B 5/686 (20130101) A61B 5/741 (20130101) A61B 5/7264 (20130101) A61B 2562/046 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 13/00 (20130101) G10L 15/02 (20130101) G10L 15/16 (20130101) G10L 15/22 (20130101) Original (OR) Class G10L 15/183 (20130101) G10L 19/00 (20130101) G10L 2015/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009061 | Peters et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | David Gerard Peters (Pittsburgh, Pennsylvania); Tianjiao Chu (Pittsburgh, Pennsylvania); Lisa Ann Pan (Pittsburgh, Pennsylvania); David N. Finegold (Pittsburgh, Pennsylvania) |
| ABSTRACT | Computational techniques are disclosed for using methylation profiles to classify the medication condition of a person. Initial sequence data is obtained containing sequences of an initial set of nucleic acids from a biological sample of a person. The initial sequence data is filtered to generate filtered sequence data that describes sequences of a filtered subset of nucleic acids from the biological sample. A methylation profile is determined for the filtered subset of nucleic acids from the biological sample. The methylation profile can be processed to determine a likelihood that the person has the specified medical condition. The system outputs an indication of the likelihood that the person has the specified medical condition. |
| FILED | Friday, April 10, 2020 |
| APPL NO | 16/846238 |
| ART UNIT | 2148 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 20/00 (20190201) G16B 30/00 (20190201) Original (OR) Class G16B 40/20 (20190201) G16B 50/20 (20190201) G16B 50/30 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12010206 | Karimi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elimu Informatics, Inc. (El Cerrito, California) |
| ASSIGNEE(S) | ELIMU INFORMATICS, INC. (El Cerrito, California) |
| INVENTOR(S) | Seemeen S. Karimi (La Jolla, California); Aziz A. Boxwala (La Jolla, California); Robert Harold Dolin (Gold Hill, Oregon) |
| ABSTRACT | A system is provided for encoding genomics data for secure storage and processing. In particular, the system may comprise a client and server operating environment that uses a unique encoding algorithm to transform genomics data and/or metadata to produce encoded genomics data and/or metadata. In some embodiments, the encoded genomics data and/or metadata may be encrypted using one or more encryption algorithms. The encoded and/or encrypted genomics data may be stored on a secure server (e.g., a cloud environment) that may perform subsequent processing steps on the encoded and/or encrypted genomics data. Once the processing steps have been completed, the server may transmit one or more outputs associated with the genomics data and/or metadata to a client device. In this way, the system provides an efficient and secure way to store and process genomics data. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 17/559449 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 50/40 (20190201) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) Original (OR) Class H04L 2209/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12010920 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Xudong Wang (Middleton, Wisconsin); Jun Li (Madison, Wisconsin) |
| ABSTRACT | An in-situ poled ferroelectric prints with true 3D geometry is provided with an intercalated electrode design where soft polymer matrixes are selected for the ferroelectric layers, and rigid polymer matrixes are selected for the electrode layers, thus mimicking nacre architecture with a ceramic-like piezoelectric property and bone-like fracture toughness. Lithium-doped potassium sodium niobite (Li—KNN) microparticles may be used to produce ferroelectric properties and to create strong interfacial bonding with the interfacing electrode layers. Polylactic acid (PLA) in the electrode layers may be used to facilitate strong interfacial bonding with the Li—KNN microparticles. |
| FILED | Monday, February 08, 2021 |
| APPL NO | 17/170382 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/11 (20180101) Electric solid-state devices not otherwise provided for H10N 30/045 (20230201) H10N 30/50 (20230201) H10N 30/057 (20230201) H10N 30/852 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12004604 | Broce et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio); Secretary Of The U.S. Army (Offutt, Nebraska) |
| INVENTOR(S) | Stephanie M. Broce (Salem, Virginia); Douglas E. Wilke (Columbus, Ohio); Timothy C. Rothwell (Columbus, Ohio); Michael A. Lorenz (Columbus, Ohio); Emily K. Stokes (Columbus, Ohio) |
| ABSTRACT | A selectively attachable garment-to-appendage interface including a seal having a first portion to a garment and a second portion coupled to an appendage such as a glove, a hood or footwear. The first portion includes one of a projection or a groove. The second portion includes the other of the projection or a groove. The projection and the groove are configured to releasably engage for selectively attaching the garment to the appendage. |
| FILED | Friday, June 18, 2021 |
| APPL NO | 17/351623 |
| ART UNIT | 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/00 (20130101) A41D 2300/324 (20130101) Buttons, Pins, Buckles, Slide Fasteners, or the Like A44B 17/0041 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12004840 | Maharbiz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michel M. Maharbiz (El Cerrito, California); Dongjin Seo (Albany, California); Konlin Shen (Oakland, California); Jose M. Carmena (Berkeley, California); Ryan Neely (Oakland, California); Elad Alon (Oakland, California); Jan Rabaey (Oakland, California) |
| ABSTRACT | Described herein are implantable devices configured to emit an electrical pulse. An exemplary implantable device includes an ultrasonic transducer configured to receive ultrasonic waves that power the implantable device and encode a trigger signal; a first electrode and a second electrode configured to be in electrical communication with a tissue and emit an electrical pulse to the tissue in response to the trigger signal; and an integrated circuit comprising an energy storage circuit. Also described are systems that include one or more implantable device and an interrogator configured to operate the one or more implantable devices. Further described is a closed loop system that includes a first device configured to detect a signal, an interrogator configured to emit a trigger signal in response to the detected signal, and an implantable device configured to emit an electrical pulse in response to receiving the trigger signal. Further described are computer systems useful for operating one or more implantable devices, as well as methods of electrically stimulating a tissue. |
| FILED | Friday, July 07, 2017 |
| APPL NO | 16/313865 |
| ART UNIT | 3798 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0031 (20130101) Original (OR) Class A61B 5/076 (20130101) A61B 5/279 (20210101) A61B 5/686 (20130101) A61B 6/4258 (20130101) A61B 8/48 (20130101) A61B 8/085 (20130101) A61B 8/0808 (20130101) A61B 8/0875 (20130101) A61B 2505/05 (20130101) A61B 2560/0219 (20130101) A61B 2562/12 (20130101) A61B 2562/028 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 39/0208 (20130101) A61M 2205/04 (20130101) A61M 2205/825 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/372 (20130101) A61N 1/0534 (20130101) A61N 1/3605 (20130101) A61N 1/3787 (20130101) A61N 1/37205 (20130101) A61N 5/1071 (20130101) A61N 2005/1087 (20130101) A61N 2007/0021 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/327 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12004971 | Rouse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); REHABILITATION INSTITUTE OF CHICAGO (Chicago, Illinois); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Elliott J. Rouse (Ann Arbor, Michigan); Maxwell Shepherd (Evanston, Illinois); Hashim Quraishi (Ann Arbor, Michigan); Leo Mcmanus (Ann Arbor, Michigan) |
| ABSTRACT | A cam system for an assistive device and related methods are disclosed. The cam system may comprise a multi (e.g., dual) cam profile and a cam follower. |
| FILED | Wednesday, May 22, 2019 |
| APPL NO | 17/057406 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/70 (20130101) A61F 2/6607 (20130101) Original (OR) Class A61F 2002/507 (20130101) A61F 2002/701 (20130101) A61F 2002/6657 (20130101) A61F 2002/6863 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005159 | Farokhnia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Nazanin Farokhnia (New York, New York); Alexandre Caprio (New York, New York); Varun Umesh Kashyap (New York, New York); Subhi Al' Aref (New York, New York); Bobak Mosadegh (New York, New York); James K. Min (New York, New York); Simon Dunham (New York, New York) |
| ABSTRACT | Systems, methods, and devices having improved conformal properties for biomedical signal measurement are disclosed. A device can have a first polymer substrate coupled to a conductive layer forming a conductive trace electrically coupled to a conductive pad exposed via an opening. The device can have a second polymer substrate forming a first cavity between the first polymer substrate and the second polymer substrate. The device can have a first inlet portion that receives a fluid that expands the first cavity causing the device to conform to an anatomical structure. The structure can be an atrium, such as the left atrium, of the heart of a patient. The device can conform to the walls of the tissue structure, and the conductive pad exposed via the opening can detect a signal from the wall of the tissue structure. The signal can be provided to an external measurement device for processing. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/774440 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2018/0022 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/08 (20130101) A61L 29/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005396 | Benton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Porifera, Inc. (San Leandro, California) |
| ASSIGNEE(S) | Porifera, Inc. (San Leandro, California) |
| INVENTOR(S) | Charles Benton (Berkeley, California); Olgica Bakajin (San Leandro, California); Carl Lundin (Honolulu, Hawaii) |
| ABSTRACT | An example water purification system for purifying high concentration feed solutions includes a high rejection forward osmosis module, one or more low rejection modules, and a high rejection reverse osmosis module. The low rejection modules may have different rejection levels. The system may be pressurized by one or more pumps. One or more of the low rejection modules may include one or more nanofiltration (NF) membranes. The draw solution may comprise a monovalent salt, a multivalent salt, or a combination of both. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/684406 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/002 (20130101) B01D 61/02 (20130101) B01D 61/06 (20130101) B01D 61/12 (20130101) B01D 61/025 (20130101) B01D 61/026 (20220801) B01D 61/027 (20130101) B01D 61/58 (20130101) Original (OR) Class B01D 65/02 (20130101) B01D 2311/14 (20130101) B01D 2311/25 (20130101) B01D 2313/243 (20130101) B01D 2313/246 (20130101) B01D 2317/02 (20130101) B01D 2317/08 (20130101) B01D 2317/025 (20130101) B01D 2321/16 (20130101) B01D 2325/20 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/441 (20130101) C02F 1/445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005419 | Ramezani |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ODH IP CORP. (New York, New York) |
| ASSIGNEE(S) | ODH IP CORP. (New York, New York) |
| INVENTOR(S) | Madhi Ramezani (Rockville, Maryland) |
| ABSTRACT | Modular reactors comprising a chassis, reactor tubing and optionally a cover are disclosed. The chassis comprises a plurality of channels of different lengths into which a length of reactor tubing is placed to create the reactor portion of the flow reactor. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/186474 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0073 (20130101) B01J 19/0093 (20130101) B01J 19/243 (20130101) B01J 19/248 (20130101) Original (OR) Class B01J 2219/00166 (20130101) B01J 2219/00894 (20130101) B01J 2219/00984 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005497 | Agarwal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida International University Board of Trustees (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Arvind Agarwal (Miami, Florida); Cheng Zhang (Miami, Florida); Tanaji Paul (Miami, Florida); Sohail Mazher Ali Khan Mohammed (Miami, Florida); Denny John (Miami, Florida) |
| ABSTRACT | Methods for large-scale additive manufacturing of high-strength boron nitride nanotubes (BNNT)/aluminum (Al) (e.g., reinforced Al alloy) metal matrix composites (MMCs) (BNNT/Al MMCs), as well as the BNNT/Al MMCs produced by the large-scale additive manufacturing methods, are provided. A combination of ultrasonication and spray drying techniques can produce good BNNT/Al alloy feedstock powders, which can be used in a cold spraying process. |
| FILED | Wednesday, December 14, 2022 |
| APPL NO | 18/065796 |
| ART UNIT | 1738 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/103 (20220101) B22F 1/0547 (20220101) Original (OR) Class B22F 10/64 (20210101) B22F 2301/052 (20130101) B22F 2302/205 (20130101) B22F 2304/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/10 (20200101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Alloys C22C 21/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005631 | Larson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Natalie M. Larson (Cambridge, Massachusetts); Jochen Mueller (Baltimore, Maryland); Jennifer A. Lewis (Cambridge, Massachusetts) |
| ABSTRACT | A printhead comprises a plurality of ink cartridges and a nozzle, where the nozzle and the ink cartridges are configured to rotate together about an axis during printing. The nozzle includes a nozzle body comprising an inlet end, an outlet end, and one or more internal passageways extending through the nozzle body from the inlet end to the outlet end. The one or more internal passageways terminate at one or more outlets at or near the outlet end. The nozzle also includes plurality of nozzle inlets at the inlet end for delivery of flowable inks into the internal passageways, where each nozzle inlet is in fluid communication with a dispensing end of one of the ink cartridges. |
| FILED | Tuesday, November 08, 2022 |
| APPL NO | 17/982877 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) Original (OR) Class B29C 64/209 (20170801) B29C 64/255 (20170801) B29C 64/264 (20170801) B29C 64/336 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006069 | Bernhardt |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Paul A. Bernhardt (Alexandria, Virginia) |
| ABSTRACT | A method and apparatus uses a VLF transmitter, a VLF receiver, and/or a low earth orbit satellite including a rocket engine. A VLF wave transmitted into space is converted to an ambient wave. The ambient wave acts as a signal wave for a whistler traveling wave parametric amplifier. Rocket exhaust is generated in atmospheric plasma. The rocket exhaust includes kinetic energy acting as a Lower Hybrid wave source. The Lower Hybrid wave source produces a Lower Hybrid wave, which acts as a pump wave for the parametric amplifier. Nonlinear mixing of the signal wave and the pump wave in the atmospheric plasma simultaneously parametrically amplifies the ambient wave and generates an idler wave and a parametrically amplified wave. The parametrically amplified wave (1) reduces the density of energetic protons or killer electrons in the Van Allen radiation belt, and (2) improves communications between the VLF transmitter and VLF receiver. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 17/547457 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/54 (20130101) B64G 1/242 (20130101) B64G 1/405 (20130101) Original (OR) Class Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0081 (20130101) F03H 1/0087 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/4645 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006071 | Allison |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | US Govt. as represented by Secretary of Air Force (Kirtland AFB, New Mexico) |
| ASSIGNEE(S) | Government of the United States as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico) |
| INVENTOR(S) | Jonathan Allison (Albuquerque, New Mexico) |
| ABSTRACT | A deployable radiator panel system for a small spacecraft includes fusible metal thermal hinge having a hinge leaf affixed to a spacecraft fixed radiator panel and the corresponding hinge leaf affixed to a deployable radiator panel with fusible metal filling the interstices between knuckles of each leaf to provide a conductive heat transfer path from the spacecraft fixed radiator panel through its leaf to the intervening fusible metal and then to the deployable radiator panel leaf and finally to the deployable radiator panel. A method is provided to heat and melt the fusible metal, release the deployable radiator panel from a stowed position, apply torque to open the fusible thermal metal hinge and latch the deployable radiator panel in a deployed position, and cool and solidify fusible metal. |
| FILED | Thursday, March 04, 2021 |
| APPL NO | 17/191702 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/503 (20130101) Original (OR) Class B64G 1/506 (20130101) Hinges or Suspension Devices for Doors, Windows or Wings E05D 3/02 (20130101) E05D 2003/027 (20130101) Devices for Moving Wings into Open or Closed Position; Checks for Wings; Wing Fittings Not Otherwise Provided For, Concerned With the Functioning of the Wing E05F 3/00 (20130101) E05F 3/22 (20130101) Indexing Scheme Relating to Hinges or Other Suspension Devices for Doors, Windows or Wings and Devices for Moving Wings into Open or Closed Position, Checks for Wings and Wing Fittings Not Otherwise Provided For, Concerned With the Functioning of the Wing E05Y 2900/502 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006206 | Painter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Oskar Painter (Sierra Madre, California); Jie Luo (Pasadena, California); Michael T. Fang (Pasadena, California); Alp Sipahigil (Pasadena, California); Paul B. Dieterle (Somerville, Massachusetts); Mahmoud Kalaee (Pasadena, California); Johannes M. Fink (Klosterneuburg, Austria); Andrew J. Keller (Los Angeles, California); Gregory MacCabe (Los Angeles, California); Hengjiang Ren (Pasadena, California); Justin D. Cohen (Annandale, Virginia) |
| ABSTRACT | Embodiments described herein include systems and techniques for converting (i.e., transducing) a quantum-level (e.g., single photon) signal between the three wave forms (i.e., optical, acoustic, and microwave). A suspended crystalline structure is used at the nanometer scale to accomplish the desired behavior of the system as described in detail herein. Transducers that use a common acoustic intermediary transform optical signals to acoustic signals and vice versa as well as microwave signals to acoustic signals and vice versa. Other embodiments described herein include systems and techniques for storing a qubit in phonon memory having an extended coherence time. A suspended crystalline structure with specific geometric design is used at the nanometer scale to accomplish the desired behavior of the system. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/866281 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 3/0029 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) G06N 10/40 (20220101) Static Stores G11C 13/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006309 | Glover et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Alabama (Mobile, Alabama) |
| ASSIGNEE(S) | University of South Alabama (Mobile, Alabama) |
| INVENTOR(S) | Thomas Grant Glover (Spanish Fort, Alabama); Kevin N. West (Mobile, Alabama) |
| ABSTRACT | Processes for chemical functionalization of materials are described. The processes generally include chemical reaction between a thiol group of a first compound or material and an alkene group or alkyne group of a second compound or material. Also disclosed are functionalized materials and compounds suitable for functionalizing a material. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/537668 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 233/74 (20130101) C07D 251/40 (20130101) C07D 403/12 (20130101) Original (OR) Class Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 13/165 (20130101) D06M 13/348 (20130101) D06M 2101/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006337 | Holtzman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri) |
| INVENTOR(S) | Michael J. Holtzman (St. Louis, Missouri); Arthur G. Romero (Chesterfield, Missouri); Benjamin J. Gerovac (St. Louis, Missouri); Zhenfu Han (St. Louis, Missouri); Shamus P. Keeler (University City, Missouri); Kangyun Wu (St. Louis, Missouri); Yong Zhang (St. Louis, Missouri) |
| ABSTRACT | Compounds that inhibit mitogen-activated protein kinases (MAPKs) are disclosed. Some inhibitor compounds specifically target a single MAPK such as MAPK13, while others target multiple MAPKs such as MAPK13 and MAPK12. The compounds can be used therapeutically for a variety of diseases, including cancer and respiratory diseases. Methods of synthesis of the compounds are also disclosed. |
| FILED | Wednesday, July 13, 2022 |
| APPL NO | 17/863657 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 213/75 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0812 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006350 | Ulery et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bret Ulery (Columbia, Missouri); Rui Zhang (Columbia, Missouri); Caitlin Leeper (Columbia, Missouri); Josiah Smith (Columbia, Missouri); Logan Morton (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Bret Ulery (Columbia, Missouri); Rui Zhang (Columbia, Missouri); Caitlin Leeper (Columbia, Missouri); Josiah Smith (Columbia, Missouri); Logan Morton (Columbia, Missouri) |
| ABSTRACT | One aspect of the present invention is directed to triblock peptides comprising a lipid moiety, a peptide block and a zwitterion-like block. Another aspect of the invention is directed to pharmaceutical compositions comprising the triblock peptides of the present in invention arranged in micelles in a pharmaceutically acceptable carrier. In certain embodiments, the pharmaceutical compositions of the present invention are vaccine compositions, which may further comprise an adjuvant. Another aspect of the invention is directed to methods of using the triblock peptides and compositions of the invention to treat a disease or condition. |
| FILED | Tuesday, October 30, 2018 |
| APPL NO | 16/760329 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) A61P 31/16 (20180101) Peptides C07K 14/77 (20130101) Original (OR) Class C07K 14/57563 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006404 | Portela et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Carlos M. Portela (Pasadena, California); Daryl Wei Liang Yee (Pasadena, California); Dennis M. Kochmann (Pasadena, California); Julia R. Greer (Pasadena, California) |
| ABSTRACT | In an aspect, provided herein are low density materials, including shell-based materials, with three-dimensional architectures formed, in part, via self-assembly processes. Shell-based materials of some embodiments exhibit a combination of ultralow density (e.g., ≤100 mg cm−3 and optionally ≤10 100 mg cm−3) and non-periodic architectures characterized by low defect densities and geometries avoiding stress concentrations. Low density shell based materials of some embodiments have architectures characterized by small curvatures and lack of straight edges providing enhance mechanical response. In some embodiments, for example, the present low density materials, including shell-based materials, providing a combination target mechanical properties including high stiffness-to-density ratios, mechanical resilience and tolerance for deformation. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/032539 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 38/0051 (20130101) C04B 38/0067 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/02 (20130101) Original (OR) Class C08J 9/26 (20130101) C08J 2363/02 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/45525 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/249953 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006411 | Hreha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Systima Technologies, Inc. (Mukilteo, Washington) |
| ASSIGNEE(S) | Systima Technologies, Inc. (Mukilteo, Washington) |
| INVENTOR(S) | Richard D. Hreha (Centerville, Ohio); Kory K. Evanson (Vandalia, Ohio); Kristopher K. Aber (Dayton, Ohio); Jeffrey R. Josken (West Carrollton, Ohio); Michael D. Rauscher (Beavercreek, Ohio) |
| ABSTRACT | Methods of producing a fiber reinforced polymer matrix composite and a composite thermal protection system formed from the same. The method includes forming a polymerized fiber reinforced composite which including a cured thermoset polymer matrix and at least one reinforcement material. The method further includes treating at least a portion of a first face of the polymerized fiber reinforced composite with electromagnetic radiation to raise the temperature of the portion of the first face to at least 800° C. to produce a surface layer of graphitized carbon and a bulk polymerized fiber reinforced composite representing the untreated polymerized fiber reinforced composite. Further, the surface layer of graphitized carbon has an electrical conductivity of 0.25 S m−1 to 2.5 S m−1 where the electrical conductivity and a thermal conductivity are both greater than those of the bulk polymerized reinforced composite. |
| FILED | Wednesday, August 18, 2021 |
| APPL NO | 17/405454 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/243 (20210501) C08J 7/123 (20130101) Original (OR) Class C08J 2363/00 (20130101) C08J 2379/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 59/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006520 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); John Paul Guilinger (Cambridge, Massachusetts); Vikram Pattanayak (Cambridge, Massachusetts) |
| ABSTRACT | Engineered nucleases are promising tools for genome manipulation and determining off-target cleavage sites of these enzymes is of great interest. This disclosure provides in vitro selection methods that interrogate 1011 DNA sequences for their ability to be cleaved by active nucleases, e.g., ZFNs and TALENs. The method revealed hundreds of thousands of DNA sequences that can be cleaved in vitro by two ZFNs, CCR5-224 and VF2468, which target the endogenous human CCR5 and VEGF-A genes, respectively. Analysis of the identified sites in cultured human cells revealed CCR5-224-induced mutagenesis at nine off-target loci. This disclosure provides an energy compensation model of ZFN specificity in which excess binding energy contributes to off-target ZFN cleavage. It was also observed that TALENs can achieve cleavage specificity similar to or higher than that observed in ZFNs. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/441751 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/44 (20130101) C12Q 1/68 (20130101) C12Q 1/68 (20130101) C12Q 1/6874 (20130101) C12Q 2521/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006532 | Kennedy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Scott R. Kennedy (Seattle, Washington); Jesse J. Salk (Seattle, Washington); Michael Hipp (Seattle, Washington); Elizabeth Schmidt (Seattle, Washington); Rosa Ana Risques (Seattle, Washington); Daniela Nachmanson (Seattle, Washington) |
| ABSTRACT | The present technology relates generally to methods and compositions for targeted nucleic acid sequence enrichment, as well as uses of such enrichment for error-corrected nucleic acid sequencing applications. In some embodiments, highly accurate, error corrected and massively parallel sequencing of nucleic acid material is possible using a combination of uniquely labeled strands in a double-stranded nucleic acid complex in such a way that each strand can be informatically related to its complementary strand, but also distinguished from it following sequencing of each strand or an amplified product derived therefrom. In various embodiments, this information can be used for the purpose of error correction of the determined sequence. |
| FILED | Friday, September 16, 2022 |
| APPL NO | 17/933058 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6855 (20130101) C12Q 2521/501 (20130101) C12Q 2525/191 (20130101) C12Q 2531/113 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006583 | Choi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | The Trustees of the Stevens Institute of Technology (Hoboken, New Jersey) |
| INVENTOR(S) | Chang-Hwan Choi (Tenafly, New Jersey); Junghoon Lee (Palisades Park, New Jersey) |
| ABSTRACT | A process includes means for depositing an anti-corrosion coating filled with liquid oil on an aluminum substrate. Aluminum is anodized and then treated with a thin hydrophobic sub-coating. The pores created through anodization are then impregnated with liquid oil. Oil penetration is maximized and residual air is minimized by first filling the pores with a filling solution, replacing the filling solution with an exchange fluid, and then replacing the exchange fluid with perfluorinated oil. The oil gives the surface coating anti-wetting properties and self-healing properties, thereby protecting the aluminum substrate underneath from corrosion. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/584160 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 11/10 (20130101) C25D 11/24 (20130101) C25D 11/246 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006592 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| INVENTOR(S) | Sang Jin Lee (Winston-Salem, North Carolina); James J. Yoo (Winston-Salem, North Carolina); Young Min Ju (Winston-Salem, North Carolina); Anthony Atala (Winston-Salem, North Carolina) |
| ABSTRACT | The invention is directed to products and methods for preparing self-seeding vascular constructs generated as a bi-layered electrospun matrices, conjugated with EPC-specific antibodies and anti-thrombogenic agents on the inner surfaces of their lumens. |
| FILED | Monday, May 10, 2021 |
| APPL NO | 17/316342 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/728 (20130101) A61K 31/729 (20130101) A61K 31/737 (20130101) A61K 35/44 (20130101) A61K 38/39 (20130101) A61K 38/363 (20130101) A61K 38/1858 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) Heterocyclic Compounds C07D 315/00 (20130101) Peptides C07K 16/18 (20130101) C07K 16/46 (20130101) C07K 16/289 (20130101) C07K 16/2896 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) Original (OR) Class D01D 5/0076 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) D01F 4/00 (20130101) D01F 6/92 (20130101) D01F 6/625 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006598 | Baughman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Ray H. Baughman (Dallas, Texas); Jiuke Mu (Plano, Texas); Monica Jung De Andrade (Dallas, Texas); Shaoli Fang (Richardson, Texas); Na Li (Dallas, Texas); Carter S. Haines (Murphy, Texas) |
| ABSTRACT | Sheath-run artificial muscles (or SRAMs) are described in which the dimensional changes and/or modulus changes of a sheath on the surface of a twisted or coiled host yarn or fiber drives torsional and tensile actuation. The sheath-core artificial muscle includes a sheath on a coiled core yarn or fiber that has inserted twist, in which the sheath does not include a yarn, the coiled core yarn or fiber includes a core yarn or fiber, the sheath can change volume, modulus, or a combination thereof when actuated by an influence source to drive actuation, and the influence source is selected from a group consisting of absorption processes, desorption processes, changes in temperature, changes in external pressure, changes in a magnetic field, changes in an electric field, exposures to actinic radiation, electrochemical charge and discharge, chemical reactions, and combinations thereof. These sheath-run muscles can be used for diverse applications, such as robots, robotic devices, energy harvesters, muscles that enable electrical energy harvesting, comfort-adjusting textiles, comfort-adjusting clothing, bio-powered intelligent muscles that control the release of drugs, muscles for appropriate drug delivery, intelligent muscles that sense their environment and actuate in response, muscles for artificial limbs and orthotic gloves, muscles for haptic applications, muscles that can perform in extreme environments, and muscles for intelligent solar panel positioning. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 17/610045 |
| ART UNIT | 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/36 (20130101) Original (OR) Class D02G 3/448 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006965 | McGann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Shawn Kerry McGann (Ridgecrest, California); Nicholas McGaha (Ridgecrest, California) |
| ABSTRACT | A connector may couple to a non-cylindrical composite tubing having at least two lateral sides disposed in parallel and an open end. The connector may comprise first and second bonding plates adhered to an inner surface of the two lateral sides via an epoxy adhesive uniformly distributed. The first and second bonding plates may each have a distal lateral face defining a plurality of first threaded holes accessible at the open end of the composite tubing. The connector may also comprise an end plate having a plurality of first and second slotted holes disposed substantially in parallel and each aligned with an associating one of the first threaded holes. The connector may also comprise end plate fasteners loosely inserted through the first and second slotted holes and engaged with the first threaded holes. The end plate may also comprise one or more attachment points. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/903380 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/48 (20130101) B29C 65/561 (20130101) B29C 66/022 (20130101) B29C 66/026 (20130101) B29C 66/5221 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/20 (20130101) Cleaning or Degreasing of Metallic Material by Chemical Methods Other Than Electrolysis C23G 1/00 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/3483 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/02 (20130101) Original (OR) Class F16B 9/01 (20180801) F16B 9/05 (20180801) F16B 11/006 (20130101) Technical Subjects Covered by Former US Classification Y10T 403/472 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007180 | Ranjan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Ram Ranjan (West Hartford, Connecticut); Kimberly R. Saviers (Glastonbury, Connecticut); Kathryn L. Kirsch (Manchester, Connecticut); Ross K. Wilcoxon (Cedar Rapids, Iowa) |
| ABSTRACT | A heat sink with a primary flow volume, an inlet, an outlet, a bottom plate, a top plate, distribution, heat transfer and collector sections, and flow paths between pillars. The inlet cross-section defines the primary flow volume cross-section and the length of the primary flow volume extends into the heat sink at a right angle to the inlet cross-section. The distribution section is proximate to the flow inlet and has distribution pillars extending from the bottom or top plate. The heat transfer section is proximate to the distribution section and has heat transfer pillars extending from the bottom or top plate. The collector section is proximate to the heat transfer section and has collector pillars extending from the bottom or top plate. The distribution cross-section is greater than the heat transfer cross-section which is smaller than the collector cross-section. The flow paths extend outside of the primary flow volume. |
| FILED | Friday, April 01, 2022 |
| APPL NO | 17/657728 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/40 (20130101) Original (OR) Class F28F 3/12 (20130101) F28F 3/022 (20130101) F28F 2215/04 (20130101) F28F 2250/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007217 | Fischer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Omnitek Partners LLC (Ronkonkoma, New York) |
| ASSIGNEE(S) | OMNITEK PARTNERS LLC (Ronkonkoma, New York) |
| INVENTOR(S) | Jacques Fischer (Sound Beach, New York); Jahangir S Rastegar (Stony Brook, New York) |
| ABSTRACT | A device including: a body having one or more walls defining an internal cavity, the wall(s) having one or more grooves extending in a longitudinal direction of the internal cavity and extending at least partially along a periphery of the wall(s); a mass movable in the longitudinal direction within the internal cavity, the mass having one or more holes extending in a direction offset from the longitudinal direction; a ball partially disposed in the groove(s) and partially disposed in each hole(s); and an elastic material for biasing the ball towards the groove(s). The groove(s) having a shape such that the acceleration greater than a predetermined acceleration profile causes the ball to first move opposite to the direction of the acceleration and then bounce to move in the direction of the acceleration until the ball(s) moves into the hole(s) to free the mass to move longitudinally opposite to the acceleration. |
| FILED | Friday, October 28, 2022 |
| APPL NO | 17/976701 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition Fuzes; Arming or Safety Means Therefor F42C 15/24 (20130101) Original (OR) Class F42C 19/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007252 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida); Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida); Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Chengying Xu (Tallahassee, Florida); Amanda Schrand (Eglin AFB, Florida); Reamonn Soto (Daytona Beach, Florida) |
| ABSTRACT | Temperature sensors, pressure sensors, methods of making the same, and methods of detecting pressures and temperatures using the same are provided. In an embodiment, the temperature sensor includes a ceramic coil inductor having a first end plate and a second end plate, wherein the ceramic coil inductor is formed of a ceramic composite that comprises carbon nanotubes or, carbon nanofibers, or a combination of carbon nanotubes and carbon nanofibers thereof dispersed in a ceramic matrix; and a thin film polymer-derived ceramic (PDC) nanocomposite disposed between the first and the second end plates, wherein the thin film PDC nanocomposite has a dielectric constant that increases monotonically with temperature. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/896530 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 3/08 (20130101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/32 (20130101) G01K 7/343 (20130101) G01K 2211/00 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/007 (20130101) G01L 9/0075 (20130101) G01L 9/105 (20130101) G01L 19/04 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 17/0006 (20130101) H01F 41/041 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007271 | Rodenbeck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Christopher T. Rodenbeck (Annandale, Virginia); Joshua B. Beun (Alexandria, Virginia); Ronald D. Lipps (San Diego, California); Raghu G. Raj (Fairfax, Virginia) |
| ABSTRACT | Systems and methods are provided for interrogating a moving acoustic source using radar and processing data using a selection of motion compensation techniques adapted from synthetic aperture radar (SAR) to remove the effects of linear and nonlinear target motion so that the range-Doppler map retains only vibration information in the Doppler dimension. Vibration and sound waveforms can thus be selectively reproduced at specific ranges directly from the radar baseband waveform, without the need for additional complex analysis or audio processing. |
| FILED | Wednesday, August 18, 2021 |
| APPL NO | 17/406040 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 9/00 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/415 (20130101) G01S 13/89 (20130101) G01S 13/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007276 | Chandrasekar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Rohith Chandrasekar (Princeton, New Jersey); Amr Shaltout (Palo Alto, California); Vladimir Shalaev (West Lafayette, Indiana); Alexander Chubykin (West Lafayette, Indiana); Alexei Lagutchev (West Lafayette, Indiana) |
| ABSTRACT | A spectroscopic microscope device, including at least one array of metasurfaces, and at least one CCD array integrated with the array of metasurfaces. The metasurfaces in the array are configured to separately direct LCP an RCP components of light incident on the metasurface to separate pixels in the CCD array. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 16/362598 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/44 (20130101) G01J 3/0237 (20130101) Original (OR) Class G01J 3/2803 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/19 (20130101) G01N 21/251 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007321 | Di Carlo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dino Di Carlo (Los Angeles, California); Daniel R. Gossett (Los Angeles, California); Henry T. K. Tse (San Francisco, California); Aram Chung (Los Angeles, California) |
| ABSTRACT | A system for deforming and analyzing a plurality of particles carried in a sample volume includes a substrate defining an inlet, configured to receive the sample volume, and an outlet; and a fluidic pathway fluidly coupled to the inlet and the outlet. The fluidic pathway includes a delivery region configured to receive the plurality of particles from the inlet and focus the plurality of particles from a random distribution to a focused state, a deformation region defining an intersection located downstream of the delivery region and coupled to the outlet, and wherein the deformation region is configured to receive the plurality of particles from the delivery region and to transmit each particle in the plurality of particles into the intersection from a single direction, a first branch fluidly coupled to the deformation region and configured to transmit a first flow into the intersection, and a second branch fluidly coupled to the deformation region and configured to transmit a second flow, substantially opposing the first flow, into the intersection, wherein the first flow and the second flow are configured to induce extension of one or more particles in the plurality of particles. |
| FILED | Friday, March 12, 2021 |
| APPL NO | 17/200728 |
| ART UNIT | 1758 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/01 (20240101) G01N 15/147 (20130101) Original (OR) Class G01N 15/1404 (20130101) G01N 15/1434 (20130101) G01N 15/1436 (20130101) G01N 15/1459 (20130101) G01N 15/1484 (20130101) G01N 21/64 (20130101) G01N 21/645 (20130101) G01N 21/6428 (20130101) G01N 33/50 (20130101) G01N 33/5091 (20130101) G01N 2015/1006 (20130101) G01N 2015/1415 (20130101) G01N 2015/1495 (20130101) G01N 2021/6439 (20130101) Image Data Processing or Generation, in General G06T 7/0004 (20130101) G06T 7/0016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007328 | Raphael et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Marc P. Raphael (Springfield, Virginia); Joseph A. Christodoulides (Alexandria, Virginia); Jeff M. Byers (Fairfax Station, Virginia); James B. Delehanty (Washington, District of Columbia) |
| ABSTRACT | Methods and systems for determining extracellular concentration data of an analyte are disclosed. A method for determining extracellular concentration data of an analyte includes receiving sensor data from one or more arrays of functionalized plasmonic nanostructures on a localized surface plasmon resonance imaging chip in contact with a fluid containing at least one living cell for a plurality of times, determining intensity data for the one or more arrays, determining fractional occupancy based on the intensity data, and determining extracellular concentration data based on the fractional occupancy data. A system for determining extracellular concentration data of an analyte includes a LSPRi chip, a sensor component, an intensity component, a fractional occupancy component, a concentration component, and a processor to implement the components. |
| FILED | Tuesday, January 21, 2020 |
| APPL NO | 16/747702 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) G01N 21/648 (20130101) Original (OR) Class G01N 21/6458 (20130101) G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007386 | Kerr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States (Air Force) (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Miami University and Government of the United States (Air Force) (, None) |
| INVENTOR(S) | Lei L. Kerr (Oxford, Ohio); Saber M. Hussain (Beavercreek, Ohio); Andrew Yerich (Oxford, Ohio) |
| ABSTRACT | The anatomical model of a nasal cavity, such as a human nasal cavity, for in-vitro inhalation studies such as toxicological screening, intranasal drug delivery studies, and neurophysiological studies. The model includes a model body including separable upper and lower model portions together defining the nasal cavity and including fluidic channels therein that define an olfactory region of the upper model portion, and a nasal passage defined in the lower model portion. A biocompatible porous membrane is positioned between the upper and lower model portions, and the biocompatible membrane is configured for culturing olfactory epithelium cells thereon. An artificial mucous layer coats a surface of the nasal cavity and is configured to collect particles passing through the nasal cavity. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/680851 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/3835 (20130101) B29C 33/3842 (20130101) B29C 39/02 (20130101) B29C 64/386 (20170801) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/40 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 50/00 (20141201) B33Y 80/00 (20141201) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0688 (20130101) C12N 2513/00 (20130101) C12N 2533/00 (20130101) C12N 2533/90 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5082 (20130101) Original (OR) Class Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 23/30 (20130101) G09B 23/34 (20130101) G09B 23/303 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007602 | Safavi-Naeini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Amir H. Safavi-Naeini (Palo Alto, California); Timothy Patrick McKenna (San Francisco, California); Hubert S. Stokowski (Stanford, California) |
| ABSTRACT | In an integrated optical device, squeezed light is used internally to effectively increase an optical modulation effect. One exemplary device operates by squeezing the light at the input, then sending it through an electro-optic stage where its phase picks up the signal of interest, and finally anti-squeezing it to obtain a displaced coherent state. Thus the displacement is amplified by the level of squeezing that is achieved inside the device and it is thereby less sensitive to loss. Since this device behaves simply as an electro-optic modulator, albeit one with an exponentially enhanced sensitivity, no extra considerations are needed to integrate the modulator into a system. Such devices can be operated as modulators or as sensors, and can make use of optical phase shift effects other than the electro-optic effect. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/740027 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/12004 (20130101) Original (OR) Class G02B 6/12007 (20130101) G02B 6/29344 (20130101) G02B 2006/1204 (20130101) G02B 2006/12138 (20130101) G02B 2006/12142 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008470 | Mireshghallah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Fatemehsadat Mireshghallah (La Jolla, California); Hadi Esmaeilzadeh (La Jolla, California); Mohammadkazem Taram (La Jolla, California) |
| ABSTRACT | Described are methods, devices and applications for learning noise distribution on information from any data processing method. In an embodiment of the described technology, a method includes determining an amount of shredding used in a shredding operation by which source data is converted into shredded data, and transferring the shredded data over an external network to a remote server for a data processing task. The shredding reduces the information content and incurs a limited degradation to an accuracy of the data processing task due to the shredding operation. |
| FILED | Friday, October 16, 2020 |
| APPL NO | 17/073143 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008747 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Hersh Bhargava (San Francisco, California); Patrick Leo (Honeoye Falls, New York); Priti Lal (Ellicott City, Maryland) |
| ABSTRACT | Embodiments discussed herein facilitate determination of one of a probability of prostate cancer recurrence-free survival or a risk factor associated with prostate cancer based on intra-tumor stromal morphology. Example embodiments can perform operations comprising: accessing a digitized histological image of a prostate of a patient, wherein the histological image comprises a region of interest associated with prostate cancer; identifying nuclei of intra-tumoral stromal cells within the region of interest; extracting, for the region of interest of the digitized histological image, one or more features describing the structure of the intra-tumoral stromal cells; and generating, via a model based at least on the one or more features, one of a probability of prostate cancer recurrence-free survival or a risk score associated with prostate cancer for the patient based at least on the extracted one or more features. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/886966 |
| ART UNIT | 2699 — Search and Capture Special Detail |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30081 (20130101) Image or Video Recognition or Understanding G06V 10/7796 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009192 | Houlahan, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Starfire Industries LLC (Champaign, Illinois) |
| ASSIGNEE(S) | Starfire Industries LLC (Champaign, Illinois) |
| INVENTOR(S) | Thomas J. Houlahan, Jr. (Urbana, Illinois); Daniel P. Menet (Urbana, Illinois); Ian F. Haehnlein (Champaign, Illinois); Ivan A. Shchelkanov (Pleasanton, California); Robert A. Stubbers (Savoy, Illinois); Brian E. Jurczyk (Champaign, Illinois) |
| ABSTRACT | A system and associated method are described for depositing high-quality films for providing a coating on a three-dimensional surface such as an internal surface of a bellows structure. The system includes a magnetic array comprising multiple sets of magnets arranged to have Hall-Effect regions that run lengthwise along a sputter target. The system further includes an elongated sputtering electrode material tube surrounding the magnetic array comprising multiple sets of magnets arranged to have Hall-Effect regions that run lengthwise along the sputter target. During operation, the system generates and controls ion flux for direct current high-power impulse magnetron sputtering. During operation logic circuitry issues a control signal to control a kick pulse property of a sustained positive voltage kick pulse taken from the group consisting of: onset delay, amplitude and duration. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/322600 |
| ART UNIT | 2896 — Electrical Circuits and Systems |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/35 (20130101) C23C 14/3485 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/3405 (20130101) H01J 37/3417 (20130101) H01J 37/3467 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009501 | DeBlock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Ryan H. DeBlock (Alexandria, Virginia); Debra R. Rolison (Arlington, Virginia); Jeffrey W. Long (Alexandria, Virginia); Zachary G. Neale (Alexandria, Virginia) |
| ABSTRACT | A method of making an electrode by providing a mixture of first particles of silver or silver oxide and second particles of an inorganic porogen, molding the mixture, cohering the mixture to form a green body, demolding the green body, heating the green body to form a monolith, to convert any silver oxide to silver, and to fuse the first particles together, and submerging the monolith in a liquid that removes the second particles. |
| FILED | Friday, June 02, 2023 |
| APPL NO | 18/328020 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/48 (20130101) H01M 4/0433 (20130101) Original (OR) Class H01M 10/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009605 | Lau |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | Anthony Y. Lau (Chantilly, Virginia) |
| ABSTRACT | Due to its geometry, spherical reflector antenna is inherently diffractive, leading to spherical aberration. Disclosed are example embodiments of methods and systems to minimize or eliminate spherical aberration in a spherical reflector antenna system. One of the systems includes: a main spherical reflecting dish; and a spherical feed having a plurality of antenna elements disposed on a spherical surface. The plurality of antenna elements can be disposed on a convex surface of the spherical surface of the spherical feed facing the main spherical reflecting dish. |
| FILED | Friday, November 08, 2019 |
| APPL NO | 16/678798 |
| ART UNIT | 2643 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/24 (20130101) H01Q 3/28 (20130101) H01Q 3/38 (20130101) H01Q 3/46 (20130101) Original (OR) Class H01Q 19/10 (20130101) H01Q 21/0025 (20130101) Transmission H04B 1/1081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009886 | Zheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lehigh University (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | Lehigh University (, None) |
| INVENTOR(S) | Yahong Rosa Zheng (Bethlehem, Pennsylvania); Xiyuan Zhu (Bethlehem, Pennsylvania) |
| ABSTRACT | An acoustic transmission device may communicate sensing data via one or more multiple-input multiple-output (MIMO) transmissions. The device may comprise a serial peripheral interface (SPI) and/or a phase shifting key (PSK) modulator. The device may be configured to provide a first SPI signal, perhaps including one or more coded information bits, to the PSK modulator. The device may provide a second SPI signal, perhaps including a synchronous clock signal, to the PSK modulator. The device may generate of one or more symbols on N transmit branches based on the first SPI signal. The device may generate of at least one carrier frequency with one or more phases to form one or more phased carriers based on the second SPI signal. The device may control a transmission of the sensing data (e.g., video) via the one or more symbols on the N transmit branches on the one or more phased carriers. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 17/745019 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Transmission H04B 7/0413 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 27/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12010512 | Manikantan Shila et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carrier Corporation (Jupiter, Florida) |
| ASSIGNEE(S) | CARRIER CORPORATION (Palm Beach Gardens, Florida) |
| INVENTOR(S) | Devu Manikantan Shila (West Hartford, Connecticut); Kunal Srivastava (Manchester, Connecticut); Paul C. O'Neill (New Britain, Connecticut) |
| ABSTRACT | A method of mobile based user authentication includes storing a plurality of categories of data associated with user activity with a mobile device carried or worn by a user. The method also includes analyzing the plurality of categories of data over a recent period of time to determine a user trust score based on a historical period of time, the historical period of time greater than the recent period of time. The method further includes granting access to an access controlled environment if the user trust score is within a predetermined score range. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 16/610026 |
| ART UNIT | 2446 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 21/32 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/535 (20220501) Wireless Communication Networks H04W 4/80 (20180201) H04W 12/06 (20130101) Original (OR) Class H04W 12/08 (20130101) H04W 12/64 (20210101) H04W 12/68 (20210101) H04W 88/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12005099 | Jackson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Paul J. Jackson (Livermore, California); Brian E. Souza (Livermore, California); Feliza A. Bourguet (Livermore, California); Matthew A. Coleman (Oakland, California) |
| ABSTRACT | Targeted antimicrobials are described and related, compositions, methods and systems. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 16/880492 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/50 (20130101) Original (OR) Class A61K 45/06 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 1/04 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Enzymes C12Y 305/01028 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/008 (20130101) G01L 9/08 (20130101) G01L 9/0052 (20130101) G01L 19/141 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/32 (20130101) G01N 2333/914 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2224/73265 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005391 | Boscoboinik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York); The Research Foundation for the State University of New York (Stony Brook, New York) |
| INVENTOR(S) | Jorge A. Boscoboinik (Stony Brook, New York); Mengen Wang (Coram, New York); Deyu Lu (South Setauket, New York); Nusnin Akter (Bronx, New York); Jianqiang Zhong (Berlin, Germany); Yixin Xu (Port Jefferson, New York); Dario J. Stacchiola (South Setauket, New York); Alejandro Miguel Boscoboinik (Milwaukee, Wisconsin) |
| ABSTRACT | A method for trapping noble gas atoms and molecules in oxide nanocages that includes providing oxide nanocages on a metallic substrate, ionizing a noble gas to form noble gas cations, applying a voltage to the metallic substrate, contacting the oxide nanocages with the noble gas cations, and deionizing the cations to form noble gas atoms and molecules that are trapped within the oxide nanocages. In one embodiment of the present device, polygonal prism organosilicate cages on a ruthenium thin film can trap noble gases. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/008198 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/32 (20130101) Original (OR) Class B01D 53/76 (20130101) B01D 2253/34 (20130101) B01D 2253/106 (20130101) B01D 2257/11 (20130101) B01D 2258/02 (20130101) B01D 2259/10 (20130101) B01D 2259/818 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/3204 (20130101) B01J 20/3297 (20130101) B01J 20/28042 (20130101) B01J 2220/42 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005392 | Voskian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Sahag Voskian (Cambridge, Massachusetts); Trevor Alan Hatton (Sudbury, Massachusetts) |
| ABSTRACT | The present disclosure generally relates to apparatuses, systems, and methods for separating a target species (e.g., CO2) from a gas mixture (e.g., gas stream) via an electrochemical process. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/685285 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 53/326 (20130101) Original (OR) Class B01D 2257/504 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/19 (20210101) C25B 11/085 (20210101) C25B 13/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005414 | Aytug et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Tolga Aytug (Knoxville, Tennessee); Kai Li (Farragut, Tennessee); Meghan E. Lamm (Oak Ridge, Tennessee); Diana Hun (Lenoir City, Tennessee); Kaushik Biswas (Davis, California) |
| ABSTRACT | An insulation medium invention includes a plurality of microspheres. Each microsphere comprises a porous core comprising a porous core material and having an exterior surface, a gas within the porous core, and a coating layer coating all of the exterior surface of the porous core. The coating layer comprises a coating material which transitions from a first state to a second state. In the first state, the coating material is permeable to the gas. In the second state the material is impermeable to the gas. The coating material in the second state is configured to encapsulate and maintain partial vacuum of the gas inside the porous core. In one embodiment, in the second state the coating is impermeable to air. Insulated structures, a method of making an insulation medium, a fluid storage media, and a method of delivering a fluid are also disclosed. |
| FILED | Friday, July 23, 2021 |
| APPL NO | 17/384317 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0004 (20130101) A61K 9/5073 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/22 (20130101) B01J 13/203 (20130101) Original (OR) Class Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/10 (20130101) B32B 27/20 (20130101) B32B 2264/303 (20200801) B32B 2264/2032 (20200801) B32B 2307/304 (20130101) B32B 2419/00 (20130101) B32B 2553/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 20/0032 (20130101) C04B 20/1029 (20130101) C04B 2111/00612 (20130101) C04B 2201/30 (20130101) Pulp Compositions; Preparation Thereof Not Covered by Subclasses D21C or D21D; Impregnating or Coating of Paper; Treatment of Finished Paper Not Covered by Class B31 or Subclass D21G; Paper Not Otherwise Provided for D21H 17/74 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/806 (20130101) Structural Elements; Building Materials E04C 2/288 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005429 | Viswanathan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
| INVENTOR(S) | Tito Viswanathan (Little Rock, Arkansas) |
| ABSTRACT | A composite is synthesized by pyrolysis of a mixture of tannin and melamine. The synthesis process comprises dissolving the tannin and the melamine in water to form a homogeneous solution; evaporating the solution to yield a dry solid; and subjecting powders of the dry solid to a heat treatment at a temperature for a duration of time effective to produce the composite. |
| FILED | Wednesday, January 20, 2021 |
| APPL NO | 17/152922 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 27/14 (20130101) B01J 27/24 (20130101) Original (OR) Class B01J 35/33 (20240101) B01J 35/39 (20240101) B01J 37/084 (20130101) B01J 37/0236 (20130101) B01J 37/346 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/05 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/30 (20130101) C02F 1/725 (20130101) C02F 2101/30 (20130101) C02F 2305/10 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/55 (20210101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/96 (20130101) H01M 4/583 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005452 | Kelly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| INVENTOR(S) | Ryan T. Kelly (West Richland, Washington); Ying Zhu (Richland, Washington); Richard D. Smith (Richland, Washington) |
| ABSTRACT | Provided herein are methods and systems for biochemical analysis, including compositions and methods for processing and analysis of small cell populations and biological samples (e.g., a robotically controlled chip-based nanodroplet platform). In particular aspects, the methods described herein can reduce total processing volumes from conventional volumes to nanoliter volumes within a single reactor vessel (e.g., within a single droplet reactor) while minimizing losses, such as due to sample evaporation. |
| FILED | Tuesday, August 17, 2021 |
| APPL NO | 17/404478 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/00317 (20130101) B01J 2219/00367 (20130101) B01J 2219/00619 (20130101) B01J 2219/00621 (20130101) B01J 2219/00659 (20130101) B01J 2219/00702 (20130101) B01J 2219/00725 (20130101) B01J 2219/00743 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/00 (20130101) B01L 3/5088 (20130101) B01L 3/50853 (20130101) B01L 3/502753 (20130101) Original (OR) Class B01L 2200/142 (20130101) B01L 2300/0819 (20130101) B01L 2300/0822 (20130101) B01L 2300/0887 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/58 (20130101) C12M 41/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 60/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 1/34 (20130101) G01N 1/2813 (20130101) G01N 30/88 (20130101) G01N 33/68 (20130101) G01N 33/4833 (20130101) G01N 2001/284 (20130101) G01N 2030/8831 (20130101) Optical Elements, Systems, or Apparatus G02B 21/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005649 | Ivanov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee); UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee); OAK RIDGE ASSOCIATED UNIVERSITIES (Oak Ridge, Tennessee) |
| INVENTOR(S) | Ilia N. Ivanov (Knoxville, Tennessee); Eric S. Muckley (San Diego, California); Reinaldo C. Reina (Brooklyn, Maryland) |
| ABSTRACT | A system for determining an age and/or quality of food or beverage based on one or more combinations of outputs from gas sensors input into a deployed machine learning model is provided. The system may comprise an electronic nose which may comprise a housing and the gas sensors. The housing may have an air channel. Each sensor has its active sensor portion in the air channel. A system for predicting one or more natural language descriptors associated with aromas of an item based on one or more outputs of the gas sensors and calculated one or more ratios input into a logistic regression model is also provided. |
| FILED | Thursday, September 23, 2021 |
| APPL NO | 17/483187 |
| ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0004 (20130101) A61B 5/0816 (20130101) A61B 5/6891 (20130101) A61B 2562/046 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/364 (20170801) B29C 64/386 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/00 (20130101) G01N 21/25 (20130101) G01N 27/026 (20130101) G01N 33/0001 (20130101) G01N 33/02 (20130101) G01N 33/0031 (20130101) G01N 33/0063 (20130101) G01N 33/0073 (20130101) G01N 33/497 (20130101) G01N 2203/0094 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/042 (20130101) G05B 2219/2614 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) G06N 5/022 (20130101) G06N 20/00 (20190101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006210 | Fathalizadeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aidin Fathalizadeh (Berkeley, California); Thang Pham (Berkeley, California); William Mickelson (Albany, California); Alexander Zettl (Kensington, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to boron nitride nanomaterials. In one aspect, a method includes generating a directed flow of plasma. A boron-containing species is introduced to the directed flow of the plasma. Boron nitride nanostructures are formed in a chamber. In another aspect, a method includes generating a directed flow of plasma using nitrogen gas. A boron-containing species is introduced to the directed flow of the plasma. The boron-containing species can consist of boron powder, boron nitride powder, and/or boron oxide powder. Boron nitride nanostructures are formed in a chamber, with a pressure in the chamber being about 3 atmospheres or greater. |
| FILED | Tuesday, May 03, 2022 |
| APPL NO | 17/661805 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/08 (20130101) B01J 2219/0879 (20130101) B01J 2219/0894 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/064 (20130101) C01B 21/0641 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/13 (20130101) C01P 2004/24 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/583 (20130101) C04B 35/622 (20130101) C04B 2235/95 (20130101) C04B 2235/767 (20130101) C04B 2235/5276 (20130101) C04B 2235/5284 (20130101) C04B 2235/5454 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/762 (20130101) Y10S 977/896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006421 | Ciesielski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Peter N. Ciesielski (Arvada, Colorado); Ruoran Zhang (Lakewood, Colorado); Michael E. Himmel (Littleton, Colorado); Andrew Nolan Wilson (Denver, Colorado); Mark R. Nimlos (Golden, Colorado) |
| ABSTRACT | Disclosed herein are a cellulose particle and a binder, where the cellulose particle has a cellulose core and a surface group, and the binder interacts with the surface group to form a composite. |
| FILED | Friday, July 10, 2020 |
| APPL NO | 16/926263 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/19 (20130101) C08K 5/098 (20130101) Compositions of Macromolecular Compounds C08L 1/02 (20130101) Original (OR) Class C08L 2203/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006506 | Mackenzie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Sally Mackenzie (Lincoln, Nebraska); Michael Fromm (Lincoln, Nebraska); Kamaldeep Virdi (Lincoln, Nebraska); Yashitola Wamboldt (Lincoln, Nebraska) |
| ABSTRACT | The present invention provides methods for obtaining plants that exhibit useful traits by perturbation of plastid function in plant rootstocks and grafting the rootstocks to scions. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants. Recombinant DNA vectors and transgenic plants comprising those vectors that provide for plastid perturbation are also provided. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/989422 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/827 (20130101) C12N 15/8218 (20130101) C12N 15/8261 (20130101) C12N 15/8269 (20130101) C12N 15/8271 (20130101) C12N 15/8273 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006570 | Elam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Jeffrey W. Elam (Elmhurst, Illinois); Joseph A. Libera (Clarendon Hills, Illinois); Angel Yanguas-Gil (Northbrook, Illinois) |
| ABSTRACT | A temporal Atomic Layer Deposition system and method utilizing precursor pulses applied to a moving substrate. The precursor pulses are self-exhausting. |
| FILED | Monday, August 20, 2018 |
| APPL NO | 16/105432 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/40 (20130101) C23C 16/52 (20130101) C23C 16/54 (20130101) C23C 16/545 (20130101) C23C 16/45527 (20130101) Original (OR) Class C23C 16/45551 (20130101) C23C 16/45553 (20130101) C23C 16/45555 (20130101) C23C 16/45574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006605 | Pegna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FREE FORM FIBERS, LLC (Saratoga Springs, New York) |
| ASSIGNEE(S) | Free Form Fibers, LLC (Saratoga Springs, New York) |
| INVENTOR(S) | Joseph Pegna (Saratoga Springs, New York); Shay L. Harrison (East Schodack, New York); Erik G. Vaaler (Redwood City, California); John L. Schneiter (Cohoes, New York) |
| ABSTRACT | A non-woven fabric is provided which includes a three-dimensional array of fibers. The three-dimensional array of fibers includes an array of standing fibers extending perpendicular to a plane of the non-woven fabric and attached to a base substrate, where the base substrate is one or more of an expendable film substrate, a metal base substrate, or a mandrel substrate. Further, the three-dimensional array of fibers includes multiple layers of non-woven parallel fibers running parallel to the plane of the non-woven fiber in between the array of standing fibers in a defined pattern of fiber layer orientations. In implementation, the array of standing fibers are grown to extend from the base substrate using laser-assisted chemical vapor deposition (LCVD). |
| FILED | Friday, July 24, 2020 |
| APPL NO | 16/938072 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/74 (20130101) Original (OR) Class D04H 1/4234 (20130101) D04H 1/4374 (20130101) D04H 1/43835 (20200501) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2403/033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006658 | Koci et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Caterpillar Inc. (Peoria, Illinois) |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Chad Koci (Washington, Illinois); Jay R. Steffen (Washington, Illinois); Fang Guo (Dunlap, Illinois); Richard W. Kruiswyk (Dunlap, Illinois); Gaurav Vasudeva (Dunlap, Illinois); Robert Michael McDavid (Dunlap, Illinois); Timothy Adam Bazyn (Chilicothe, Illinois) |
| ABSTRACT | A power system may include a high-speed flywheel connected to an engine of a machine; a battery; a motor-generator unit (MGU) connected to the engine and the battery; and a turbocharger connected to the engine. One or more of the high-speed flywheel, the battery and the MGU, or the turbocharger may be configured to provide supplemental power to power provided by the engine to operate the machine, or provide replacement power when no power is provided by the engine to operate the machine. |
| FILED | Friday, April 09, 2021 |
| APPL NO | 17/301651 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Dredging; Soil-shifting E02F 9/202 (20130101) E02F 9/2075 (20130101) Original (OR) Class E02F 9/2091 (20130101) E02F 9/2095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006762 | Bhandari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Mahabir Bhandari (Knoxville, Tennessee); Ahmed A. Hassen (Knoxville, Tennessee); Bipin Shah (Fairfax, Virginia); Derek Byrd (Knoxville, Tennessee) |
| ABSTRACT | A vacuum insulated glazing includes first and second spaced apart glass panes having perimeter portions defining a vacuum space between the glass panes. A vacuum valve is positioned at the perimeter portions of the glass panes and includes a valve body extending between the perimeter portions of the glass panes, and having first and second ends and a fluid conduit extending from the first end to the second end of the valve body and in fluid communication with the vacuum space. A one-way valve in the fluid conduit permits fluid flow from the vacuum space, and prevents fluid flow into the vacuum space. A suction fitting is provided for connecting the valve body to a suction device. An end seal between the perimeter portions of the glass panes is provided for hermetically sealing the vacuum space. A valve for a VIG and a method of making a VIG are also disclosed. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 17/570931 |
| ART UNIT | 3635 — Static Structures, Supports and Furniture |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 3/6612 (20130101) Original (OR) Class E06B 3/6775 (20130101) E06B 3/66333 (20130101) E06B 3/66342 (20130101) E06B 3/67326 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 15/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006884 | Shirley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hyundai Motor Company (Seoul, South Korea); Kia Corporation (Seoul, South Korea) |
| ASSIGNEE(S) | Hyundai Motor Company (Seoul, South Korea); Kia Corporation (Seoul, South Korea) |
| INVENTOR(S) | Mark Shirley (Albion, Michigan); Nicholas Fantin (Ann Arbor, Michigan); Shengrong Zhu (Ann Arbor, Michigan); Kyoung Pyo Ha (Gyeonggi-do, South Korea); Jeffrey Hollowell (Commerce, Michigan); Nahm Roh Joo (Gyeonggi-do, South Korea) |
| ABSTRACT | Systems and methods for having discrete valve opening and closing timings for different pairs of the combustion cylinders, and transitioning an engine from a Low temperature Combustion (LTC) mode to a Gasoline Compression Ignition (GCI) mode are provided. The method may comprise performing a cold start on an engine, comprising at least two sets of cylinders, in a Spark Ignition (SI) mode. The method may comprise, using a discrete camshaft operation for different pairs of the combustion cylinders to run the at least two sets of cylinders in the LTC mode, and when a load operation point of the engine increases, transitioning a first set of cylinders, of the at least two sets of cylinders, to run in a SI mode, and, after the first set of cylinders is transitioned to run in the SI mode, transitioning the second set of cylinders to run in the GCI mode, and, after the second set of cylinders is transitioned to run in the GCI mode, transitioning the first set of cylinders to run in the GCI mode. |
| FILED | Thursday, March 02, 2023 |
| APPL NO | 18/177527 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Controlling Combustion Engines F02D 13/0215 (20130101) Original (OR) Class F02D 41/008 (20130101) F02D 41/064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007171 | Reid et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Robert Stowers Reid (Santa Fe, New Mexico); Morgan T. Biel (Los Alamos, New Mexico); Lindsey M. Gaspar (Santa Fe, New Mexico); Kirk Weisbrod (Los Alamos, New Mexico); Katrina M. Sweetland (Los Alamos, New Mexico); Robert A. Zimmerman (Los Alamos, New Mexico) |
| ABSTRACT | A method for forming an annular heat pipe wick in a controlled atmosphere includes wrapping a plurality of layers of a fine mesh screen around a mandrel to form a wick. The method also includes inserting the mandrel and the wick into a sheath, and compressing the wick between the sheath and the mandrel to form an assembly. The compressing of the wick comprises applying pressure to an exterior of the mandrel and the sheath. The method further includes diffusion bonding the assembly at a temperature sufficiently high achieving self-diffusion of the plurality of layers of the fine mesh screen used to form the wick to themselves. The method also includes cooling the diffusion bonded assembly to room temperature, and etching the mandrel and sheath from the diffusion bonded assembly, leaving the wick as a porous tube. |
| FILED | Monday, March 29, 2021 |
| APPL NO | 17/216398 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 31/027 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/26 (20130101) B23P 2700/09 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/046 (20130101) Original (OR) Class Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 2275/061 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007461 | Tedeschi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jonathan R. Tedeschi (Richland, Washington); A. Mark Jones (West Richland, Washington) |
| ABSTRACT | A shared aperture antenna array including an array of antennas is disclosed. Elements of neighboring antennas are shared to create additional antennas. The shared elements include radiating patches and apertures. Each antenna shares an aperture with neighboring antennas. The array of antennas may be linear or two-dimensional. A phase shifting network with single-pole-single-throw reflective switches may be coupled to the antennas. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/169344 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/03 (20130101) G01S 13/02 (20130101) Original (OR) Class G01S 2013/0254 (20130101) Antennas, i.e Radio Aerials H01Q 9/285 (20130101) H01Q 9/0435 (20130101) H01Q 21/0006 (20130101) H01Q 21/24 (20130101) H01Q 21/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007738 | Wilde et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| INVENTOR(S) | Torsten Wilde (Berlin, Germany); Jeffrey C. Hanson (Lakewood, Ohio); Aamir Arshad Rashid (Sharon, Massachusetts); Michael McKay (Wellesley, Canada) |
| ABSTRACT | In some examples, a controller dynamically configures a property associated with monitoring performed by an agent. The controller stores, in a repository, metadata relating to the agent. The controller receives, from the agent, first sensor data that excludes the metadata, and uses indexing information in the first sensor data to retrieve the metadata from the repository. |
| FILED | Monday, March 29, 2021 |
| APPL NO | 17/215238 |
| ART UNIT | 2459 — Computer Networks |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/0428 (20130101) Original (OR) Class G05B 2219/24015 (20130101) G05B 2219/25068 (20130101) Electric Digital Data Processing G06F 16/164 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007899 | Zaidy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Aliasger Tayeb Zaidy (Seattle, Washington); David Andrew Roberts (Wellesley, Massachusetts); Patrick Michael Sheridan (Boulder, Colorado); Lukasz Burzawa (Seattle, Washington) |
| ABSTRACT | Disclosed in some examples are improved address prediction and memory preloading that leverages next-delta prediction and/or far-delta prediction for scheduling using a DNN. Previous memory access sequence data that identify one or more memory addresses previously accessed by one or more processors of a system may be processed and then converted into a sequence of delta values. The sequence of delta values are then mapped to one or more classes that are then input to a DNN. The DNN then outputs a predicted future class identifier sequence that represents addresses that the DNN predicts will be accessed by the processor in the future. The predicted future class identifier sequence is then converted back to a predicted delta value sequence and back into a set of one or more predicted addresses. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/867371 |
| ART UNIT | 2137 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0646 (20130101) G06F 12/0882 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008243 | Dugan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Michael Keith Dugan (Richardson, Texas); Tony M. Brewer (Plano, Texas) |
| ABSTRACT | A system includes a host device, a memory device, and a command manager configured to reorder respective command responses for corresponding commands between the host device and the memory device. The command manager is further configured to receive a command response associated with a transaction identifier for each command. An index value for the command is written to a reordering queue. In response to a command response write for the command response, the index value from the reordering queue is read. The index value is written in an index update queue. A network write index update message is transmitted. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 17/979390 |
| ART UNIT | 2133 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0616 (20130101) Original (OR) Class G06F 3/0659 (20130101) G06F 3/0673 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008800 | De et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Illinois) |
| INVENTOR(S) | Debraj De (Knoxville, Tennessee); Rutuja Gurav (Riverside, California); Junchuan Fan (Knoxville, Tennessee); Gautam Thakur (Knoxville, Tennessee) |
| ABSTRACT | A prediction system harvests geo-tagged ground-level images through one or more algorithms. The system receives point of interest data representing structures or events and tags the geo-tagged ground-level images with a probability describing a classification. The system tags point of interest data with a hierarchical genre classification and encodes the tagged geo-tagged ground-level images as vectors to form nodes and edges in a proximity graph. The system encodes tagged points of interest data as similarity vectors to render more nodes and more edges on the proximity graph associated with the tagged geo-tagged ground-level images nodes by calculated semantic distances. The system splits the proximity graph into a training subgraph and a testing subgraph and trains a neural network by aggregating and sampling information from neighboring nodes within the training subgraph graph and validates through the testing subgraph. Training ends when a loss measurement is below a threshold. |
| FILED | Wednesday, October 25, 2023 |
| APPL NO | 18/383633 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/764 (20220101) G06V 10/774 (20220101) Original (OR) Class G06V 10/776 (20220101) G06V 20/50 (20220101) G06V 20/70 (20220101) Pictorial Communication, e.g Television H04N 19/46 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009111 | Gates |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | David Gates (Princeton, New Jersey) |
| ABSTRACT | Disclosed herein is a stellarator comprising two sets of coils, namely a set of encircling coils which encircle the plasma axis, and a set of shaping coils which do not encircle any other coil or the plasma. In some embodiments, the encircling coils include a structural element to maintain their shape under magnetic forces. In some embodiments, the shaping coils are mounted onto one or more structural elements which, together with the shaping coils, constitute a field shaping unit. Also disclosed is a controller which may modify the electrical current flowing in one or more subsets of the coils in order to achieve target plasma parameters. Also disclosed is a method of designing a set of shaping coils by discretizing a surface dipole or current potential distribution. |
| FILED | Friday, March 10, 2023 |
| APPL NO | 18/119981 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Fusion Reactors G21B 1/055 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 6/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009475 | Yi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); MONTANA STATE UNIVERSITY (Bozeman, Montana) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Montana State University (Bozeman, Montana) |
| INVENTOR(S) | Eongyu Yi (Richmond, California); Marca Doeff (Hayward, California); Guoying Chen (Oakland, California); Stephen Sofie (Manhattan, Montana) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to an all-solid-state battery including a solid electrolyte. In one aspect, a device includes a first layer of an ionically conducting oxide, a second layer of the ionically conducting oxide disposed on the first layer, and an anode disposed on the second layer of the ionically conducting oxide. The first layer defines through pores having a tortuosity of about 1. The first layer includes transition metal oxide particles and an ionically conducting solid disposed in the through pores. The transition metal oxide particles are a cathode. The first layer and the ionically conducting solid are an electrolyte. The second layer does not define any through pores. The second layer is a separator. |
| FILED | Wednesday, November 11, 2020 |
| APPL NO | 17/095483 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/381 (20130101) H01M 4/382 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/625 (20130101) H01M 4/1391 (20130101) H01M 4/5825 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0045 (20130101) H01M 2300/0068 (20130101) H01M 2300/0077 (20130101) H01M 2300/0091 (20130101) H01M 2300/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009509 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Hsien-Han Wang (Downers Grove, Illinois); Ritesh Jagatramka (Chicago, Illinois); Samuel Plunkett (Chicago, Illinois); Larry A. Curtiss (Downers Grove, Illinois); Khalil Amine (Oak Brook, Illinois) |
| ABSTRACT | An electrochemical device includes a lithium anode having a red poly(benzonitrile) coating covering at least a portion of the anode; a separator and an air cathode comprising reduced graphene oxide over gas diffusion layer; and an electrolyte comprising an ether solvent, benzonitrile, and a lithium salt. |
| FILED | Thursday, January 26, 2023 |
| APPL NO | 18/101663 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/382 (20130101) H01M 4/885 (20130101) H01M 4/926 (20130101) H01M 4/8882 (20130101) H01M 12/08 (20130101) H01M 2004/027 (20130101) H01M 2004/028 (20130101) H01M 2300/0028 (20130101) H01M 2300/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009525 | Komini Babu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Siddharth Komini Babu (Los Alamos, New Mexico); Jacob Schatz Spendelow (Los Alamos, New Mexico); Rangachary Mukundan (Los Alamos, New Mexico) |
| ABSTRACT | A polymer electrolyte fuel cell (PEFC), comprises a first electrode and a second electrode, wherein the first electrode includes a coaxial nanowire electrode. In some embodiments, the coaxial nanowire electrode comprises a plurality of ionomer nanowires, and a catalyst coating that coats at least part of the ionomer nanowires. Moreover, in some embodiments, a nanowire of the plurality of ionomer nanowires and a section of the catalyst coating that coats the nanowire form two coaxial cylinders. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/839685 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8673 (20130101) H01M 4/8892 (20130101) Original (OR) Class H01M 8/1004 (20130101) H01M 2008/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009784 | Fenning et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | David Fenning (Solana Beach, California); Rishi Kumar (San Diego, California); Guillaume von Gastrow (La Jolla, California) |
| ABSTRACT | A method for moisture testing of a fully assembled photovoltaic (PV) module. An assembled PV module is probed with short wave IR probe energy in the range of 1700-2000 nm. Energy reflected from the assembled PV module is collected and directed to a sensor. Noise is removed from a signal of the sensor with reference to the probe energy. Absorption is of the probe energy is determined. The absorption is correlated to moisture in the PV module. A preferred system that carries out the method provides a signal-to-noise ratio (as defined by standard deviation/mean of measured reflectance) of at least 3800. |
| FILED | Tuesday, April 28, 2020 |
| APPL NO | 17/604921 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3554 (20130101) G01N 2201/065 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 50/15 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009816 | Turner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NVIDIA Corp. (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA CORP. (Santa Clara, California) |
| INVENTOR(S) | Walker Joseph Turner (Jacksonville, Florida); John Poulton (Chapel Hill, North Carolina); Sanquan Song (Mountain View, California) |
| ABSTRACT | A level-shifting circuits utilizing storage cells for shifting signals low-to-high or high-to-low include control drivers with moving supply voltages. The moving supply voltages may power positive or negative supply terminals of the control drivers. The control drivers drive gates of common-source configured devices coupled to storage nodes of the storage cell. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 17/932052 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 3/037 (20130101) H03K 3/356165 (20130101) H03K 19/0013 (20130101) H03K 19/018521 (20130101) Original (OR) Class H03K 19/018528 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12010225 | Qi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Bing Qi (Knoxville, Tennessee) |
| ABSTRACT | A system and a receiver for generating quantum key(s) using conjugated homodyne detection is provided. The receiver may communicate with a transmitter via an insecure quantum channel and a classical channel to generate the quantum key(s). A decoder, in the receiver, may determine, based at least in part on quadratures X, P measured by conjugated homodyne detectors, a raw-key signal corresponding to a key signal generated by the transmitter, and a distribution of photon numbers corresponding to a quantum signal received via the insecure quantum channel. Information about the key signal is exchanged between the receiver and the transmitter via the classical channel and used to determine a quantum bit error rate of the determined raw-key signal. A gain is also obtained. A secure-key rate is calculated based at least in part on the gain, the quantum bit error rate, and the photon number distribution. |
| FILED | Monday, March 21, 2022 |
| APPL NO | 17/699904 |
| ART UNIT | 2434 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0858 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12010908 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Jian Li (Tempe, Arizona); Yunlong Ji (Mesa, Arizona) |
| ABSTRACT | Metal-assisted delayed fluorescent emitters employing benzo-imidazo-phenanthridine and analogues for full color displays and lighting applications. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/332100 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/006 (20130101) C07F 15/0033 (20130101) C07F 15/0086 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/185 (20130101) C09K 2211/1044 (20130101) C09K 2211/1074 (20130101) Organic electric solid-state devices H10K 50/11 (20230201) H10K 50/854 (20230201) H10K 85/341 (20230201) Original (OR) Class H10K 85/342 (20230201) H10K 85/346 (20230201) H10K 2101/10 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12004855 | Hall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Drew Hall (La Jolla, California); Saurabh Kulkarni (La Jolla, California) |
| ABSTRACT | An implantable biosensor may be placed subcutaneously to monitor the concentration of an analyte in a body fluid. The biosensor may include an electrochemical cell and an antenna. The components of the biosensor, including the electrochemical cell and the antenna, may be disposed on a same substrate. The electrochemical cell may include multiple electrodes for performing electrochemical measurements that include a first measurement of the analyte concentration in the body fluid, a second measurement of a background interference present in the body fluid, and a third measurement of a pH level within the body fluid. The antenna may receive, from a transceiver, radio frequency (RF) waves for wirelessly powering the implantable biosensor. The antenna may further transmit, back to the transceiver, a backscatter signal encoding a result of the electrochemical measurements. |
| FILED | Thursday, June 07, 2018 |
| APPL NO | 16/620337 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) A61B 5/0031 (20130101) A61B 5/145 (20130101) A61B 5/14532 (20130101) Original (OR) Class A61B 5/14539 (20130101) A61B 5/14865 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12005631 | Larson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Natalie M. Larson (Cambridge, Massachusetts); Jochen Mueller (Baltimore, Maryland); Jennifer A. Lewis (Cambridge, Massachusetts) |
| ABSTRACT | A printhead comprises a plurality of ink cartridges and a nozzle, where the nozzle and the ink cartridges are configured to rotate together about an axis during printing. The nozzle includes a nozzle body comprising an inlet end, an outlet end, and one or more internal passageways extending through the nozzle body from the inlet end to the outlet end. The one or more internal passageways terminate at one or more outlets at or near the outlet end. The nozzle also includes plurality of nozzle inlets at the inlet end for delivery of flowable inks into the internal passageways, where each nozzle inlet is in fluid communication with a dispensing end of one of the ink cartridges. |
| FILED | Tuesday, November 08, 2022 |
| APPL NO | 17/982877 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) Original (OR) Class B29C 64/209 (20170801) B29C 64/255 (20170801) B29C 64/264 (20170801) B29C 64/336 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006206 | Painter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Oskar Painter (Sierra Madre, California); Jie Luo (Pasadena, California); Michael T. Fang (Pasadena, California); Alp Sipahigil (Pasadena, California); Paul B. Dieterle (Somerville, Massachusetts); Mahmoud Kalaee (Pasadena, California); Johannes M. Fink (Klosterneuburg, Austria); Andrew J. Keller (Los Angeles, California); Gregory MacCabe (Los Angeles, California); Hengjiang Ren (Pasadena, California); Justin D. Cohen (Annandale, Virginia) |
| ABSTRACT | Embodiments described herein include systems and techniques for converting (i.e., transducing) a quantum-level (e.g., single photon) signal between the three wave forms (i.e., optical, acoustic, and microwave). A suspended crystalline structure is used at the nanometer scale to accomplish the desired behavior of the system as described in detail herein. Transducers that use a common acoustic intermediary transform optical signals to acoustic signals and vice versa as well as microwave signals to acoustic signals and vice versa. Other embodiments described herein include systems and techniques for storing a qubit in phonon memory having an extended coherence time. A suspended crystalline structure with specific geometric design is used at the nanometer scale to accomplish the desired behavior of the system. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/866281 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 3/0029 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) G06N 10/40 (20220101) Static Stores G11C 13/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006210 | Fathalizadeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aidin Fathalizadeh (Berkeley, California); Thang Pham (Berkeley, California); William Mickelson (Albany, California); Alexander Zettl (Kensington, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to boron nitride nanomaterials. In one aspect, a method includes generating a directed flow of plasma. A boron-containing species is introduced to the directed flow of the plasma. Boron nitride nanostructures are formed in a chamber. In another aspect, a method includes generating a directed flow of plasma using nitrogen gas. A boron-containing species is introduced to the directed flow of the plasma. The boron-containing species can consist of boron powder, boron nitride powder, and/or boron oxide powder. Boron nitride nanostructures are formed in a chamber, with a pressure in the chamber being about 3 atmospheres or greater. |
| FILED | Tuesday, May 03, 2022 |
| APPL NO | 17/661805 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/08 (20130101) B01J 2219/0879 (20130101) B01J 2219/0894 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/064 (20130101) C01B 21/0641 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/13 (20130101) C01P 2004/24 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/583 (20130101) C04B 35/622 (20130101) C04B 2235/95 (20130101) C04B 2235/767 (20130101) C04B 2235/5276 (20130101) C04B 2235/5284 (20130101) C04B 2235/5454 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/762 (20130101) Y10S 977/896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006506 | Mackenzie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Sally Mackenzie (Lincoln, Nebraska); Michael Fromm (Lincoln, Nebraska); Kamaldeep Virdi (Lincoln, Nebraska); Yashitola Wamboldt (Lincoln, Nebraska) |
| ABSTRACT | The present invention provides methods for obtaining plants that exhibit useful traits by perturbation of plastid function in plant rootstocks and grafting the rootstocks to scions. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants. Recombinant DNA vectors and transgenic plants comprising those vectors that provide for plastid perturbation are also provided. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/989422 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/827 (20130101) C12N 15/8218 (20130101) C12N 15/8261 (20130101) C12N 15/8269 (20130101) C12N 15/8271 (20130101) C12N 15/8273 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006542 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Shoujun Xu (Houston, Texas); Qiongzheng Hu (Houston, Texas); Yuhong Wang (Houston, Texas) |
| ABSTRACT | Embodiments of the present disclosure pertain to methods of utilizing force-modulated hybridization to determine the length of an analyte strand, to determine an unknown nucleic acid sequence, or to determine the binding of a nucleotide to an active agent. Additional embodiments of the present disclosure pertain to sample holder devices and methods of utilizing such devices. Further embodiments of the present disclosure pertain to detection devices. |
| FILED | Monday, June 11, 2018 |
| APPL NO | 16/620571 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 7/52 (20130101) B01L 2200/0663 (20130101) B01L 2300/18 (20130101) B01L 2300/044 (20130101) B01L 2300/0654 (20130101) B01L 2300/0672 (20130101) B01L 2400/0439 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6818 (20130101) C12Q 1/6874 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007276 | Chandrasekar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Rohith Chandrasekar (Princeton, New Jersey); Amr Shaltout (Palo Alto, California); Vladimir Shalaev (West Lafayette, Indiana); Alexander Chubykin (West Lafayette, Indiana); Alexei Lagutchev (West Lafayette, Indiana) |
| ABSTRACT | A spectroscopic microscope device, including at least one array of metasurfaces, and at least one CCD array integrated with the array of metasurfaces. The metasurfaces in the array are configured to separately direct LCP an RCP components of light incident on the metasurface to separate pixels in the CCD array. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 16/362598 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/44 (20130101) G01J 3/0237 (20130101) Original (OR) Class G01J 3/2803 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/19 (20130101) G01N 21/251 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007321 | Di Carlo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dino Di Carlo (Los Angeles, California); Daniel R. Gossett (Los Angeles, California); Henry T. K. Tse (San Francisco, California); Aram Chung (Los Angeles, California) |
| ABSTRACT | A system for deforming and analyzing a plurality of particles carried in a sample volume includes a substrate defining an inlet, configured to receive the sample volume, and an outlet; and a fluidic pathway fluidly coupled to the inlet and the outlet. The fluidic pathway includes a delivery region configured to receive the plurality of particles from the inlet and focus the plurality of particles from a random distribution to a focused state, a deformation region defining an intersection located downstream of the delivery region and coupled to the outlet, and wherein the deformation region is configured to receive the plurality of particles from the delivery region and to transmit each particle in the plurality of particles into the intersection from a single direction, a first branch fluidly coupled to the deformation region and configured to transmit a first flow into the intersection, and a second branch fluidly coupled to the deformation region and configured to transmit a second flow, substantially opposing the first flow, into the intersection, wherein the first flow and the second flow are configured to induce extension of one or more particles in the plurality of particles. |
| FILED | Friday, March 12, 2021 |
| APPL NO | 17/200728 |
| ART UNIT | 1758 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/01 (20240101) G01N 15/147 (20130101) Original (OR) Class G01N 15/1404 (20130101) G01N 15/1434 (20130101) G01N 15/1436 (20130101) G01N 15/1459 (20130101) G01N 15/1484 (20130101) G01N 21/64 (20130101) G01N 21/645 (20130101) G01N 21/6428 (20130101) G01N 33/50 (20130101) G01N 33/5091 (20130101) G01N 2015/1006 (20130101) G01N 2015/1415 (20130101) G01N 2015/1495 (20130101) G01N 2021/6439 (20130101) Image Data Processing or Generation, in General G06T 7/0004 (20130101) G06T 7/0016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007354 | Burch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kenneth S. Burch (Brighton, Massachusetts); Tim van Opijnen (Somerville, Massachusetts); Jianmin Gao (Newton, Massachusetts); Narendra Kumar (Brighton, Massachusetts); Juan C. Ortiz-Marquez (Brighton, Massachusetts); Wenjian Wang (Brighton, Massachusetts); Mason Gray (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Kenneth S. Burch (Brighton, Massachusetts); Tim van Opijnen (Somerville, Massachusetts); Jianmin Gao (Newton, Massachusetts); Narendra Kumar (Brighton, Massachusetts); Juan C. Ortiz-Marquez (Brighton, Massachusetts); Wenjian Wang (Brighton, Massachusetts); Mason Gray (Chestnut Hill, Massachusetts) |
| ABSTRACT | A method and system for label-free detection of pathogenic and antibiotic resistant bacteria is disclosed. The method includes fabricating a G-FET/peptide device having a synthesized peptide probe capable of recognizing and binding to a bacterial target; performing electric-field assisted binding of at least one bacterial cell of the bacterial target to the G-FET/peptide device; and electrically detecting the binding of the at least one bacterial cell to the G-FET/peptide device. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/090982 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) Original (OR) Class G01N 27/4146 (20130101) G01N 27/4148 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007376 | Lebedev et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trace-Ability, Inc. (Van Nuys, California) |
| ASSIGNEE(S) | Trace-Ability, Inc. (Van Nuys, California) |
| INVENTOR(S) | Artem Y. Lebedev (Santa Monica, California); Arkadij M. Elizarov (Woodland Hills, California) |
| ABSTRACT | A method for determining a concentration of a synthesis component in a radiopharmaceutical sample comprises providing an indicator, a metal or a metal complex, contacting the radiopharmaceutical sample with the indicator, metal or metal complex for a period of time sufficient to obtain an interaction, measuring an optical characteristic of the interacted components, and determining a concentration of the synthesis component in the radiopharmaceutical sample based on the measured optical characteristic. |
| FILED | Tuesday, December 15, 2020 |
| APPL NO | 17/122496 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/037 (20130101) Apparatus for Enzymology or Microbiology; C12M 41/36 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/51 (20130101) G01N 21/78 (20130101) G01N 21/82 (20130101) G01N 21/253 (20130101) G01N 33/15 (20130101) Original (OR) Class G01N 2021/752 (20130101) G01N 2033/0093 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007695 | Magnusson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Robert Magnusson (Arlington, Texas); Kyu Lee (Euless, Texas); Hafez Hemmati (Arlington, Texas); Pawarat Bootpakdeetam (Arlington, Texas) |
| ABSTRACT | A method of fabricating a metasurface comprises coating a photoresist film onto a substrate and loading the coated substrate into a laser interference lithography setup, exposing the photoresist film via a laser with a first interference pattern, the first interference pattern having a first period and a first exposure energy, subsequently exposing the coated substrate with a second interference pattern, the second interference pattern having a second period and a second exposure energy, developing the exposed portions of the photoresist film to form a periodic pattern in the photoresist, and transferring the periodic pattern into the substrate, the substrate supporting an appropriate film system that embodies the final metasurface device. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150171 |
| ART UNIT | 1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0035 (20130101) G03F 7/094 (20130101) G03F 7/162 (20130101) G03F 7/70408 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008462 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | Mi Zhang (Okemos, Michigan); Biyi Fang (Lansing, Michigan); Xiao Zeng (Lansing, Michigan) |
| ABSTRACT | Systems and methods are disclosed which allow mobile devices, and other resource constrained applications, to more efficiently and effectively utilize deep learning neural networks using only (or primarily) local resources. These systems and methods take the dynamics of runtime resources into account to enable resource-aware, multi-tenant on-device deep learning for artificial intelligence functions for use in tasks like mobile vision systems. The multi-capacity framework enables deep learning models to offer flexible resource-accuracy trade-offs and other similar balancing of performance and resources consumed. At runtime, various systems disclosed herein may dynamically select the optimal resource-accuracy trade-off for each deep learning model to fit the model's resource demand to the system's available runtime resources and the needs of the task being performed by the model. In doing so, systems and methods disclosed herein can efficiently utilize the limited resources in mobile systems to maximize performance of multiple concurrently running neural network-based applications. |
| FILED | Friday, August 09, 2019 |
| APPL NO | 17/267467 |
| ART UNIT | 2198 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 18/285 (20230101) G06F 18/2148 (20230101) Computer Systems Based on Specific Computational Models G06N 3/10 (20130101) G06N 3/045 (20230101) G06N 3/063 (20130101) Original (OR) Class G06N 3/082 (20130101) Image or Video Recognition or Understanding G06V 10/95 (20220101) G06V 20/40 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008470 | Mireshghallah et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Fatemehsadat Mireshghallah (La Jolla, California); Hadi Esmaeilzadeh (La Jolla, California); Mohammadkazem Taram (La Jolla, California) |
| ABSTRACT | Described are methods, devices and applications for learning noise distribution on information from any data processing method. In an embodiment of the described technology, a method includes determining an amount of shredding used in a shredding operation by which source data is converted into shredded data, and transferring the shredded data over an external network to a remote server for a data processing task. The shredding reduces the information content and incurs a limited degradation to an accuracy of the data processing task due to the shredding operation. |
| FILED | Friday, October 16, 2020 |
| APPL NO | 17/073143 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008747 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Hersh Bhargava (San Francisco, California); Patrick Leo (Honeoye Falls, New York); Priti Lal (Ellicott City, Maryland) |
| ABSTRACT | Embodiments discussed herein facilitate determination of one of a probability of prostate cancer recurrence-free survival or a risk factor associated with prostate cancer based on intra-tumor stromal morphology. Example embodiments can perform operations comprising: accessing a digitized histological image of a prostate of a patient, wherein the histological image comprises a region of interest associated with prostate cancer; identifying nuclei of intra-tumoral stromal cells within the region of interest; extracting, for the region of interest of the digitized histological image, one or more features describing the structure of the intra-tumoral stromal cells; and generating, via a model based at least on the one or more features, one of a probability of prostate cancer recurrence-free survival or a risk score associated with prostate cancer for the patient based at least on the extracted one or more features. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/886966 |
| ART UNIT | 2699 — Search and Capture Special Detail |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30081 (20130101) Image or Video Recognition or Understanding G06V 10/7796 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008751 | Buckler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| INVENTOR(S) | Andrew J. Buckler (Boston, Massachusetts); Mark A. Buckler (Wenham, Massachusetts) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Friday, May 07, 2021 |
| APPL NO | 17/314766 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009283 | Agonafer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Damena Agonafer (St. Louis, Missouri); Binjian Ma (St. Louis, Missouri); Li Shan (St. Louis, Missouri); Patricia Weisensee (St. Louis, Missouri); John Mark Meacham (St. Louis, Missouri) |
| ABSTRACT | A heat exchanger for thermal management of an electronic device includes a liquid delivery layer thermally coupled to the electronic device and configured to receive a liquid from a source. The heat exchanger also includes an evaporation layer comprising hollow pillars configured to receive a continuous flow of the liquid from the liquid delivery layer and evaporate the continuous flow of the liquid from droplets maintained on the hollow pillars. Each hollow pillar has an evaporation surface and a pore configured to channel the continuous flow of the liquid through the hollow pillar to the evaporation surface. The evaporation surface being configured to maintain a droplet on the respective hollow pillar within a contact line. The evaporation surface has a wetting efficiency of at least about 95% and the contact line has a length of less than about 0.0314 mm. |
| FILED | Friday, August 23, 2019 |
| APPL NO | 17/267539 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/427 (20130101) Original (OR) Class H01L 23/3735 (20130101) H01L 25/0655 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20318 (20130101) H05K 7/20327 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009876 | Prothero et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Astrapi Corporation (Dallas, Texas) |
| ASSIGNEE(S) | Astrapi Corporation (Dallas, Texas) |
| INVENTOR(S) | Jerrold Prothero (Delray Beach, Florida); Tanay Bhatt (Richardson, Texas) |
| ABSTRACT | Systems, devices, software, and methods of the present invention enable frequency-based signal power analyses in software suitable for signal with either stationary and non-stationary spectrums. The methods that may be used throughout various systems including transmitters receivers, repeater, controllers, monitors, etc. and in software simulators to enable various signal power calculations and analyses, such as frequency spectrum analysis, throughout operating systems and that may be consistently applied in system design and operation simulations in a wide range of applications, such as interference and spectrum monitoring or clearance, object tracking, transmission channel and noise analyses, radiated power analysis, signal boundary interference, satellite downlink signal identification, pulsed radar monitoring, audio detection and identification, lidar systems, sonar systems, etc. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 17/530445 |
| ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Electric Digital Data Processing G06F 2218/02 (20230101) Transmission H04B 17/23 (20150115) Original (OR) Class H04B 17/26 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009886 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lehigh University (Bethlehem, Pennsylvania) |
| ASSIGNEE(S) | Lehigh University (, None) |
| INVENTOR(S) | Yahong Rosa Zheng (Bethlehem, Pennsylvania); Xiyuan Zhu (Bethlehem, Pennsylvania) |
| ABSTRACT | An acoustic transmission device may communicate sensing data via one or more multiple-input multiple-output (MIMO) transmissions. The device may comprise a serial peripheral interface (SPI) and/or a phase shifting key (PSK) modulator. The device may be configured to provide a first SPI signal, perhaps including one or more coded information bits, to the PSK modulator. The device may provide a second SPI signal, perhaps including a synchronous clock signal, to the PSK modulator. The device may generate of one or more symbols on N transmit branches based on the first SPI signal. The device may generate of at least one carrier frequency with one or more phases to form one or more phased carriers based on the second SPI signal. The device may control a transmission of the sensing data (e.g., video) via the one or more symbols on the N transmit branches on the one or more phased carriers. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 17/745019 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Transmission H04B 7/0413 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 27/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009903 | Lucia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Brandon Lucia (Pittsburgh, Pennsylvania); Bradley Denby (Pittsburgh, Pennsylvania) |
| ABSTRACT | A system and method of controlling a constellation of nanosatellites colocates processing resources with sensors in each satellite. Latencies in data transmission are addressed by organizing the constellation of satellites into computational pipelines. An orbital edge computing module simulates system design for mission design, planning and analysis in addition to supporting online autonomy. |
| FILED | Thursday, April 01, 2021 |
| APPL NO | 17/220861 |
| ART UNIT | 2414 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 7/18513 (20130101) Original (OR) Class H04B 7/18515 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12010137 | Boyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BitSight Technologies, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | BitSight Technologies, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Stephen Wayne Boyer (Waltham, Massachusetts); Nagarjuna Venna (Waltham, Massachusetts); Megumi Ando (Cambridge, Massachusetts) |
| ABSTRACT | A method and system for creating a composite security rating from security characterization data of a third party computer system. The security characterization data is derived from externally observable characteristics of the third party computer system. Advantageously, the composite security score has a relatively high likelihood of corresponding to an internal audit score despite use of externally observable security characteristics. Also, the method and system may include use of multiple security characterizations all solely derived from externally observable characteristics of the third party computer system. |
| FILED | Tuesday, August 22, 2023 |
| APPL NO | 18/453488 |
| ART UNIT | 2492 — Cryptography and Security |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0639 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/062 (20130101) H04L 43/0876 (20130101) H04L 61/5007 (20220501) H04L 63/145 (20130101) H04L 63/1433 (20130101) Original (OR) Class H04L 67/53 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12006030 | Geuther et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTE BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Steven C. Geuther (Hampton, Virginia); David D. North (Williamsburg, Virginia); Robert G. McSwain (Yorktown, Virginia); Michael D. Patterson (Yorktown, Virginia); Gregory Howland (Yorktown, Virginia); Jared S. Fell (Yorktown, Virginia); Christopher M. Cagle (Yorktown, Virginia); Xiaofan Fei (Bellevue, Washington); Siena K. S. Whiteside (Poquoson, Virginia); David A. Hare (Smithfield, Virginia) |
| ABSTRACT | An aircraft wing configuration for a vertical or a short take-off and landing aircraft having a plurality of propeller-blown wings mounted at different longitudinal locations along a fuselage of the vertical take-off and landing aircraft, producing two or more lifting surfaces, fixed at a predetermined acute wing angle greater than 0° and substantially less than 90° relative to a horizontal plane, and having a plurality of flaps disposed behind the wings. The configuration has a plurality of propellers distributed in front of the plurality of wings producing two or more lifting surfaces and mounted such that the wings are externally blown by forced airstreams from the propellers. The propellers produce distributed thrust components, and the plurality of flaps are in the forced airstreams of the propellers when one or more of the flaps is in an extended position. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 16/857954 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 9/00 (20130101) B64C 9/04 (20130101) B64C 11/46 (20130101) B64C 13/02 (20130101) B64C 29/0025 (20130101) Original (OR) Class B64C 39/08 (20130101) B64C 2009/005 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/24 (20130101) B64D 31/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006922 | Gray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Timothy G. Gray (Cleveland, Ohio); Gabriel F. Benavides (Cleveland, Ohio) |
| ABSTRACT | Precision flow restrictors and techniques for manufacturing the same for ion thruster manifolds are disclosed. Flow restricting features are moved out of the manifold base and into separate flow restrictors, allowing a wider range of manufacturing techniques and materials to be applied. Quality control can be performed at the level of the flow restrictors as subcomponents, ensuring that only good parts with ideal flow characteristics make it into the final assembly and improving the yield rate of the final manifold assembly. |
| FILED | Monday, February 24, 2020 |
| APPL NO | 16/799079 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/405 (20130101) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0012 (20130101) Original (OR) Class F03H 1/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007472 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Yang Wang (Boulder, Colorado); Yu T. Morton (Boulder, Colorado) |
| ABSTRACT | A digital direct line-of-sight (DLOS) intermediate frequency (IF) signal of a DLOS component of an RF carrier signal transmitted by a transmitter located above the surface of the earth and a digital reflected IF signal of a reflected component of the carrier signal that is reflected from a specular point (SP) on the surface of the earth are received. Modeled reference signal parameters are generated using the digital DLOS IF signal and known locations of one or more receiving antennas, the transmitter, and the SP. A reference signal is generated based on the modeled reference signal parameters and feedback of a previously estimated Δϕ. The reference signal is correlated with the digital reflected IF signal to produce in-phase (I) and quadrature-phase (Q) correlation results. An estimated C/N0 and an estimated Δϕ for the digital reflected IF signal are calculated from the correlation results. |
| FILED | Wednesday, June 21, 2023 |
| APPL NO | 18/338662 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/003 (20130101) G01S 13/89 (20130101) Original (OR) Class G01S 19/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007729 | Ilic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New Electricity Transmission Software Solutions, Inc. (Sudbury, Massachusetts) |
| ASSIGNEE(S) | New Electricity Transmission Software Solutions, Inc. (Sudbury, Massachusetts) |
| INVENTOR(S) | Marija Ilic (Sudbury, Massachusetts); Kevin Bachovchin (Jefferson Hills, Pennsylvania); Sanja Cvijic (Arlington, Massachusetts); Jeffrey Lang (Sudbury, Massachusetts) |
| ABSTRACT | Disclosed herein are methods and systems for modeling and controlling the disparate components (e.g. generators, storage, propulsors, and power electronics) that comprise an aircraft turbo-electric distributed power (TeDP) system. The resulting control system is hierarchical and interactive. Layer one is the physical electric power system. Layer three is an optimization system that determines set points for system operation. Layer two, in between layer one and layer three, includes nonlinear, fast, dynamic power-electronic controllers that hold the operation of the power system to the desired set points. Communication between these layers ensures feasibility and stability of the controlled operation. Simulations demonstrate that the resulting control system ensures stability and maximum efficiency. |
| FILED | Tuesday, October 30, 2018 |
| APPL NO | 16/174736 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 2221/00 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/04 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 1/10 (20130101) H02J 1/16 (20130101) H02J 2310/44 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12010531 | Barsoum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Constellation Designs, LLC (Wayne, Pennsylvania) |
| ASSIGNEE(S) | Constellation Designs, LLC (Wayne, Pennsylvania) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/443733 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 15/00 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) H04L 27/3809 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 12004514 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mississippi State University (Starkville, Mississippi); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas); Mississippi State University (Starkville, Mississippi) |
| INVENTOR(S) | James Leif Smith (College Station, Texas); Akshaya Ravichandran (College Station, Texas); Shien Lu (Starkville, Mississippi); Ganyu Gu (Painter, Virginia) |
| ABSTRACT | Occidiofungin is a cyclic nonribosomally synthesized antifungal peptide with submicromolar activity. This invention is directed to compositions enriched for particular occidiofungin diastereomers/conformers, methods of making compositions enriched for particular diastereomers/conformers and microorganisms suitable for producing enriched compositions of particular diastereomers/conformers. Methods of treating fungal infections or plants infected by fungi are also provided. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/113764 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/713 (20130101) A01N 63/20 (20200101) A01N 63/50 (20200101) Original (OR) Class A01N 63/50 (20200101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/12 (20130101) Peptides C07K 7/54 (20130101) C07K 7/56 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Enzymes C12Y 301/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12006506 | Mackenzie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Sally Mackenzie (Lincoln, Nebraska); Michael Fromm (Lincoln, Nebraska); Kamaldeep Virdi (Lincoln, Nebraska); Yashitola Wamboldt (Lincoln, Nebraska) |
| ABSTRACT | The present invention provides methods for obtaining plants that exhibit useful traits by perturbation of plastid function in plant rootstocks and grafting the rootstocks to scions. Methods for identifying genetic loci that provide for useful traits in plants and plants produced with those loci are also provided. In addition, plants that exhibit the useful traits, parts of the plants including seeds, and products of the plants are provided as well as methods of using the plants. Recombinant DNA vectors and transgenic plants comprising those vectors that provide for plastid perturbation are also provided. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/989422 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/827 (20130101) C12N 15/8218 (20130101) C12N 15/8261 (20130101) C12N 15/8269 (20130101) C12N 15/8271 (20130101) C12N 15/8273 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008730 | Ampatzidis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Ioannis Ampatzidis (Gainesville, Florida); Victor H. Meirelles Partel (Gainesville, Florida); Lucas Fideles Costa (Gainesville, Florida) |
| ABSTRACT | Embodiments of the present disclosure provide methods, apparatus, systems, computing devices, computing entities, and/or the like for detecting objects located in an area of interest. In accordance with one embodiment, a method is provided comprising: receiving, via an interface provided through a general instance on a cloud environment, imaging data comprising raw images collected on the area of interest; upon receiving the images: activating a central processing unit (CPU) focused instance on the cloud environment and processing, via the image, the raw images to generate an image map of the area of interest; and after generating the image map: activating a graphical processing unit (GPU) focused instance on the cloud environment and performing object detection, via the image, on a region within the image map by applying one or more object detection algorithms to the region to identify locations of the objects in the region. |
| FILED | Monday, June 05, 2023 |
| APPL NO | 18/328897 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/40 (20230101) Image Data Processing or Generation, in General G06T 1/20 (20130101) G06T 3/4038 (20130101) Original (OR) Class G06T 7/38 (20170101) G06T 7/70 (20170101) G06T 7/97 (20170101) G06T 2207/20104 (20130101) G06T 2207/30188 (20130101) Image or Video Recognition or Understanding G06V 10/16 (20220101) G06V 10/25 (20220101) G06V 10/82 (20220101) G06V 10/94 (20220101) G06V 10/95 (20220101) G06V 10/96 (20220101) G06V 10/945 (20220101) G06V 20/17 (20220101) G06V 20/188 (20220101) G06V 2201/07 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 12005735 | Cooper et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia); University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Rory Cooper (Pittsburgh, Pennsylvania); Jonathan Duvall (Pittsburgh, Pennsylvania); Robert McDonough (Grove City, Pennsylvania); Aaron Tyler Anderson (Philadelphia, Pennsylvania); Siew Seang Ong (Singapore, Singapore); Jeffrey Ruffing (Pittsburgh, Pennsylvania) |
| ABSTRACT | A wheelchair can comprise: a frame comprising an upper portion and a lower portion that is coupled to the upper portion so that the upper portion is vertically adjustable with respect to the lower portion. A pair of drive wheels can be coupled to the frame. A plurality (e.g., a pair) of casters are coupled to the frame. Each caster can have a respective swivel axis. At least one caster of the plurality of casters can be configured to be locked to prevent swiveling about its respective swivel axis and unlocked to enable swiveling about its respective swivel axis. |
| FILED | Friday, March 12, 2021 |
| APPL NO | 17/200324 |
| ART UNIT | 3611 — Signal Processing and Control Processing in Disk Drives |
| CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/10 (20130101) A61G 5/1051 (20161101) A61G 5/1059 (20130101) Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion B60B 33/025 (20130101) B60B 33/0039 (20130101) B60B 33/0049 (20130101) B60B 33/0068 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008747 | Madabhushi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Hersh Bhargava (San Francisco, California); Patrick Leo (Honeoye Falls, New York); Priti Lal (Ellicott City, Maryland) |
| ABSTRACT | Embodiments discussed herein facilitate determination of one of a probability of prostate cancer recurrence-free survival or a risk factor associated with prostate cancer based on intra-tumor stromal morphology. Example embodiments can perform operations comprising: accessing a digitized histological image of a prostate of a patient, wherein the histological image comprises a region of interest associated with prostate cancer; identifying nuclei of intra-tumoral stromal cells within the region of interest; extracting, for the region of interest of the digitized histological image, one or more features describing the structure of the intra-tumoral stromal cells; and generating, via a model based at least on the one or more features, one of a probability of prostate cancer recurrence-free survival or a risk score associated with prostate cancer for the patient based at least on the extracted one or more features. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/886966 |
| ART UNIT | 2699 — Search and Capture Special Detail |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/30081 (20130101) Image or Video Recognition or Understanding G06V 10/7796 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D1030430 | Dostal |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Joseph A. Dostal (Temple, Texas) |
| ABSTRACT | |
| FILED | Tuesday, March 22, 2022 |
| APPL NO | 29/831651 |
| ART UNIT | 2917 — Design |
| CURRENT CPC | Tools and hardware D8/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 12007324 | Tao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Yang Tao (Potomac, Maryland); Anjana Hevaganinge (Rockville, Maryland); Chiao-Yi Wang (College Park, Maryland); Dongyi Wang (Fayetteville, Arkansas); Mohamed Amr Ali (College Park, Maryland) |
| ABSTRACT | A non-contact system for the sensing of pH includes a hyperspectral imaging device configured to capture a hyperspectral image of a fluid, a flow cell configured to enable the capturing of a hyperspectral image of a fluid, a process, and a memory. The memory includes instructions stored thereon, which, when executed by the processor, cause the system to generate a hyperspectral image of the fluid in the flow cell, generate several spectral signals based on the hyperspectral image, provide the spectral signal as an input to a machine learning network, and predict by the machine learning network a pH of a fluid. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860428 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) G01J 3/2823 (20130101) G01J 2003/2843 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/359 (20130101) G01N 21/3577 (20130101) Original (OR) Class G01N 2201/126 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12009418 | Bertness et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Kristine Ann Bertness (Boulder, Colorado); Matthew David Brubaker (Louisville, Colorado); Patrick John Fay (Granger, Indiana) |
| ABSTRACT | A core-shell nanofin vertical switch performs high-voltage switching and includes: an n-type GaN nanofin core including: an n-type drift layer; an n-type channel; and an n-type source; a p-type nanofin shell surrounding the n-type GaN nanofin core at an interface surface of the n-type GaN nanofin core, and comprising GaN; an optional source contact disposed on the n-type GaN nanofin core and the p-type nanofin shell and in electrical communication with the n-type source, such that the n-type source is interposed between the source contact and the n-type channel; and a gate contact disposed on the p-type nanofin shell and in electrical communication with the p-type nanofin shell, such that the p-type nanofin shell is interposed between the gate contact and the n-type channel, and the gate contact is interposed between the source contact and a drain contact. |
| FILED | Wednesday, August 24, 2022 |
| APPL NO | 17/821977 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/205 (20130101) H01L 29/0634 (20130101) H01L 29/2003 (20130101) H01L 29/7788 (20130101) Original (OR) Class H01L 29/66462 (20130101) Pulse Technique H03K 17/6871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 12005403 | Dicicco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Signature Science, LLC (Charlottesville, Virginia); Government of The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | Signature Science, LLC (Charlottesville, Virginia); Government of The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Joseph A. Dicicco (Cape May Court House, New Jersey); Paul M. Flanigan, IV (Marlton, New Jersey); David Perry (Austin, Texas); John Brady (Medford, New Jersey); Barry Smith (Egg Harbor City, New Jersey) |
| ABSTRACT | Disclosed is a mixing chamber apparatus suitable for high-volume sampling (HVS) application. The mixing chamber apparatus includes, among other elements, inlet and outlet manifolds, a mixing chamber, and a tubing manifold for the introduction of clean, turbulent air into the mixing chamber. The inlet manifold defines a plurality of vapor ports that can be in fluid communication with one or more vapor sources to be sampled and mixed within the mixing chamber. Also described herein is a baffled mixing system that can be used alone or in combination with the disclosed mixing chamber apparatus. |
| FILED | Thursday, August 05, 2021 |
| APPL NO | 17/395191 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 23/19 (20220101) Original (OR) Class B01F 25/4231 (20220101) B01F 35/513 (20220101) B01F 2035/3511 (20220101) B01F 2101/23 (20220101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12010512 | Manikantan Shila et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carrier Corporation (Jupiter, Florida) |
| ASSIGNEE(S) | CARRIER CORPORATION (Palm Beach Gardens, Florida) |
| INVENTOR(S) | Devu Manikantan Shila (West Hartford, Connecticut); Kunal Srivastava (Manchester, Connecticut); Paul C. O'Neill (New Britain, Connecticut) |
| ABSTRACT | A method of mobile based user authentication includes storing a plurality of categories of data associated with user activity with a mobile device carried or worn by a user. The method also includes analyzing the plurality of categories of data over a recent period of time to determine a user trust score based on a historical period of time, the historical period of time greater than the recent period of time. The method further includes granting access to an access controlled environment if the user trust score is within a predetermined score range. |
| FILED | Monday, February 26, 2018 |
| APPL NO | 16/610026 |
| ART UNIT | 2446 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 21/32 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/535 (20220501) Wireless Communication Networks H04W 4/80 (20180201) H04W 12/06 (20130101) Original (OR) Class H04W 12/08 (20130101) H04W 12/64 (20210101) H04W 12/68 (20210101) H04W 88/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 12006126 | Davidowitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BioTillion, LLC (Skillman, New Jersey) |
| ASSIGNEE(S) | Bio Tillion, LLC (Skillman, New Jersey) |
| INVENTOR(S) | Hananel Davidowitz (Princeton, New Jersey); Theodore N. Altman (East Windsor, New Jersey); Ke Wang (Flemington, New Jersey); Zhengyan Zhai (Doylestown, Pennsylvania); Jeremy Basch (Middlesex, New Jersey); Ron Or (Moshav Bney Atarot, Israel) |
| ABSTRACT | A technique for tracking, for example, the temperature of one or more sample vials containing biological material stored in a low-temperature shipping vessel. Each sample vial has vial electronics that senses temperature and transmits temperature data to the reader head of a reader device, which has a controller that is not at the low temperature. In some implementations, the shipping vessel has a cap with a recess that houses the controller and a hollow plug that houses a cable that connects the controller to the reader head that is located in the vessel's cold interior sufficiently close to the sample vial to enable interaction with the vial electronics. In some implementations, the reader head transmits electrical power to the vial electronics. By tracking the temperature of individual sample vials rather than the temperature of the vessel interior, more-relevant temperature data is available. |
| FILED | Thursday, September 03, 2020 |
| APPL NO | 17/011518 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/1412 (20130101) A61J 2200/44 (20130101) A61J 2200/50 (20130101) A61J 2200/72 (20130101) A61J 2205/60 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 81/3825 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008751 | Buckler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| INVENTOR(S) | Andrew J. Buckler (Boston, Massachusetts); Mark A. Buckler (Wenham, Massachusetts) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Friday, May 07, 2021 |
| APPL NO | 17/314766 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 12008508 | Karpenko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Christopher James Karpenko (Rochester, New York); William G. Ackerman (Washington, District of Columbia); Dominik Heinrich (New York, New York); Christiane Braun-Rubino (Long Island City, New York); Anthony Jones (Brooklyn, New York); Daniel Karlsson (Brooklyn, New York); Jordan Diatlo (New York, New York); Daniel Bersak (New York, New York) |
| ABSTRACT | A receptacle device which detects when mail has been delivered to the receptacle using a pressure sensor, IR beam, and/or a magnetic sensor. The receptacle device is connected to a wireless or wired network and is configured to communicate with a smart home system at the delivery point. The receptacle detects mail delivery and communicates this information via a network bridge to the smart home device of the recipient. The network bridge also gathers information from an informed delivery system which includes information regarding and images of mailpieces being delivered for a given day. The network bridge sends images of mailpieces which were delivered and additional mailpiece information to the recipient on the smart home system. For parcel, the network bridge can receive information regarding parcels to be delivered and can provide delivery estimates and visual tracking on a map. |
| FILED | Tuesday, January 07, 2020 |
| APPL NO | 16/736234 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/042 (20130101) G05B 2219/25257 (20130101) Electric Digital Data Processing G06F 16/953 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0832 (20130101) Original (OR) Class G06Q 10/0833 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/2832 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12008517 | McLellan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Charles P. McLellan (Fairfax, Virginia); Venkat Mouli (Chantilly, Virginia) |
| ABSTRACT | A system and method for the use of geo-fences to coordinate and track delivery of items. In some embodiments, the system comprising a mobile delivery device comprising a vector calculation module configured to determine a motion vector associated with the mobile delivery device, a geo-location module configured to determine a geo-location associated with a mobile delivery device, and a geo-fence database configured to determine a size of at least one geo-fence associated with at least one location and determine whether the mobile delivery device is within the geo-fence. In some embodiments, the size of the geo-fence is determined at least in part on the motion vector determined by the vector calculation module. |
| FILED | Monday, December 05, 2022 |
| APPL NO | 18/061815 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0833 (20130101) G06Q 10/08355 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/021 (20130101) H04W 4/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 12006238 | Whitehill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government, as represented by the Administrator of the U.S. EPA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES GOVERNMENT, AS REPRESENTED BY THE ADMINISTRATOR OF THE U.S. EPA (Washington, District of Columbia) |
| INVENTOR(S) | Andrew Richard Whitehill (Durham, North Carolina); Eben Daniel Thoma (Cary, North Carolina); Paul Lemieux (Cary, North Carolina); Mark Higuchi (Chapel Hill, North Carolina); Chelsea Berg (Durham, North Carolina); Brian K. Gullett (Durham, North Carolina); Erin Shields (Cary, North Carolina) |
| ABSTRACT | Methods and systems are provided for processing PFAS-contaminated waste via thermomechanochemical (TMC) processing. In one example, a system may include a TMC processing chamber including a milling system and coupled to a heating system, the heating system configured to co-operate with the milling system to process the waste material. A plurality of containers including the waste material in one or more of a liquid-solid state, a semi-wet or slurry solid state, and a dry solid state are coupled to the TMC chamber. |
| FILED | Wednesday, September 29, 2021 |
| APPL NO | 17/449439 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Disposal of Solid Waste B09B 3/40 (20220101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 11/004 (20130101) C02F 11/13 (20190101) C02F 11/18 (20130101) Original (OR) Class C02F 2101/36 (20130101) C02F 2303/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 12006598 | Baughman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Ray H. Baughman (Dallas, Texas); Jiuke Mu (Plano, Texas); Monica Jung De Andrade (Dallas, Texas); Shaoli Fang (Richardson, Texas); Na Li (Dallas, Texas); Carter S. Haines (Murphy, Texas) |
| ABSTRACT | Sheath-run artificial muscles (or SRAMs) are described in which the dimensional changes and/or modulus changes of a sheath on the surface of a twisted or coiled host yarn or fiber drives torsional and tensile actuation. The sheath-core artificial muscle includes a sheath on a coiled core yarn or fiber that has inserted twist, in which the sheath does not include a yarn, the coiled core yarn or fiber includes a core yarn or fiber, the sheath can change volume, modulus, or a combination thereof when actuated by an influence source to drive actuation, and the influence source is selected from a group consisting of absorption processes, desorption processes, changes in temperature, changes in external pressure, changes in a magnetic field, changes in an electric field, exposures to actinic radiation, electrochemical charge and discharge, chemical reactions, and combinations thereof. These sheath-run muscles can be used for diverse applications, such as robots, robotic devices, energy harvesters, muscles that enable electrical energy harvesting, comfort-adjusting textiles, comfort-adjusting clothing, bio-powered intelligent muscles that control the release of drugs, muscles for appropriate drug delivery, intelligent muscles that sense their environment and actuate in response, muscles for artificial limbs and orthotic gloves, muscles for haptic applications, muscles that can perform in extreme environments, and muscles for intelligent solar panel positioning. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 17/610045 |
| ART UNIT | 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/36 (20130101) Original (OR) Class D02G 3/448 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 12008730 | Ampatzidis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Ioannis Ampatzidis (Gainesville, Florida); Victor H. Meirelles Partel (Gainesville, Florida); Lucas Fideles Costa (Gainesville, Florida) |
| ABSTRACT | Embodiments of the present disclosure provide methods, apparatus, systems, computing devices, computing entities, and/or the like for detecting objects located in an area of interest. In accordance with one embodiment, a method is provided comprising: receiving, via an interface provided through a general instance on a cloud environment, imaging data comprising raw images collected on the area of interest; upon receiving the images: activating a central processing unit (CPU) focused instance on the cloud environment and processing, via the image, the raw images to generate an image map of the area of interest; and after generating the image map: activating a graphical processing unit (GPU) focused instance on the cloud environment and performing object detection, via the image, on a region within the image map by applying one or more object detection algorithms to the region to identify locations of the objects in the region. |
| FILED | Monday, June 05, 2023 |
| APPL NO | 18/328897 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/40 (20230101) Image Data Processing or Generation, in General G06T 1/20 (20130101) G06T 3/4038 (20130101) Original (OR) Class G06T 7/38 (20170101) G06T 7/70 (20170101) G06T 7/97 (20170101) G06T 2207/20104 (20130101) G06T 2207/30188 (20130101) Image or Video Recognition or Understanding G06V 10/16 (20220101) G06V 10/25 (20220101) G06V 10/82 (20220101) G06V 10/94 (20220101) G06V 10/95 (20220101) G06V 10/96 (20220101) G06V 10/945 (20220101) G06V 20/17 (20220101) G06V 20/188 (20220101) G06V 2201/07 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 12007468 | Campbell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Tewksbury, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Tewksbury, Massachusetts) |
| INVENTOR(S) | James D. Campbell (Hermosa Beach, California); Charles T. Hansen (Palos Verdes Estates, California) |
| ABSTRACT | A circuit comprises a receive processing window formation subsystem, a matched filter subsystem, a keystone interpolation subsystem, a phase modulation subsystem, and an image forming subsystem. The receive processing window formation subsystem forms, for each radar return from a scene, a receive processing window containing the radar return as an unbroken radar return. The matched filter subsystem creates a motion model for a reference point target disposed at a predetermined location within the scene, based on a set of motion compensation parameters for range and range rate, to compensate for at least some effects of fast time Doppler on the reference point target. The keystone interpolation subsystem rescales slow time information from the matched filter subsystem. A phase modulation subsystem applies phase modulations to a keystone-interpolated 2-D output array of information associated with the scene, to ensure proper registration in a range-Doppler map output of the scene. |
| FILED | Friday, December 10, 2021 |
| APPL NO | 17/643639 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/2883 (20210501) G01S 13/003 (20130101) G01S 13/53 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12007730 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kevinlab Co. (Ansan-si, South Korea) |
| ASSIGNEE(S) | Kevinlab Co. (Ansan-si, South Korea) |
| INVENTOR(S) | Kyung Hak Kim (Suwon-si, South Korea); Sung Hwan Choi (Seoul, South Korea) |
| ABSTRACT | A method of managing data is proposed. The method includes collecting information, wherein detection values respectively matched to time points successive in time series are continuously collected, dividing sections, wherein a reference section is set, and remaining time points is divided into a correction section, calculating an equation, wherein a time point of the reference section and a detection value matched thereto are respectively set as a reference time point and a reference value, performing correction, wherein correction values calculated according to a time interval are calculated, verifying accuracy, wherein whether a ratio of the time points of the correction section to the time points is less than or equal to a preset allowable ratio is checked, and storing the data, wherein the reference value, equation, detection values or correction values, and correspondingly matched time points are stored as the data for the reference section and correction section. |
| FILED | Tuesday, February 07, 2023 |
| APPL NO | 18/106869 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Original (OR) Class G05B 2219/2642 (20130101) Electric Digital Data Processing G06F 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 11, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
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FUNDED BY
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Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
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FILED
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APPL NO
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3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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