FedInvent™ Patents
Patent Details for Tuesday, June 18, 2024
This page was updated on Wednesday, June 19, 2024 at 08:03 AM GMT
Department of Defense (DOD)
US 12011252 | Saini et al. |
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FUNDED BY |
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APPLICANT(S) | Teliatry, Inc. (Richardson, Texas) |
ASSIGNEE(S) | Teliatry, Inc. (Richardson, Texas) |
INVENTOR(S) | Rahul Saini (Allen, Texas); Dane William Grasse (Santa Clara, California); Vishnoukumaar Sivaji (Richardson, Texas) |
ABSTRACT | In one embodiment, a sensor includes a capsule having a cavity and a sheath, a transducer coupled to electronic circuitry in the cavity, and a clip outside the capsule. The capsule and the clip are configured to hold in vivo an object within an opening between the capsule and the clip. The transducer is configured to detect an incoming signal indicative of a physiological parameter of the object being held, and the electronic circuitry is configured to wirelessly transmit a signal containing information about the physiological parameter obtained from the incoming signal. The sensor is part of a measurement system to measure the physiological parameter. Another embodiment describes a method using the measurement system. |
FILED | Monday, April 19, 2021 |
APPL NO | 17/233776 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0031 (20130101) A61B 5/076 (20130101) A61B 5/0538 (20130101) A61B 5/1473 (20130101) A61B 5/02158 (20130101) Original (OR) Class A61B 5/6861 (20130101) A61B 5/6898 (20130101) A61B 5/14539 (20130101) A61B 6/425 (20130101) A61B 8/12 (20130101) A61B 2560/0214 (20130101) A61B 2562/164 (20130101) A61B 2562/0233 (20130101) A61B 2562/0247 (20130101) A61B 2562/0261 (20130101) A61B 2562/0271 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/20 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011375 | Perry et al. |
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APPLICANT(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
ASSIGNEE(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
INVENTOR(S) | N. Christopher Perry (Manchester, New Hampshire); Christopher O. Evans (Amherst, New Hampshire); Dirk A. van der Merwe (Canterbury, New Hampshire); Stewart M. Coulter (Bedford, New Hampshire); Keith D. Violette (Sandown, New Hampshire); Thomas A. Doyon (Manchester, New Hampshire) |
ABSTRACT | A system for powering a prosthetic arm is disclosed. The system includes at least one internal battery located in the prosthetic arm, at least one external battery connected to the prosthetic arm, and a master controller configured to connect either the at least one internal battery or the at least one external battery to a power bus to power the prosthetic arm. |
FILED | Thursday, June 30, 2016 |
APPL NO | 15/198929 |
ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) A61F 2/70 (20130101) Original (OR) Class A61F 2/74 (20210801) A61F 2/78 (20130101) A61F 2/581 (20130101) A61F 2/582 (20130101) A61F 2/585 (20130101) A61F 2/586 (20130101) A61F 2002/587 (20130101) A61F 2002/701 (20130101) A61F 2002/702 (20130101) A61F 2002/704 (20130101) A61F 2002/705 (20130101) A61F 2002/708 (20130101) A61F 2002/764 (20130101) A61F 2002/768 (20130101) A61F 2002/769 (20130101) A61F 2002/5001 (20130101) A61F 2002/5061 (20130101) A61F 2002/5083 (20130101) A61F 2002/6836 (20130101) A61F 2002/6845 (20130101) A61F 2002/6881 (20130101) A61F 2002/7625 (20130101) A61F 2002/7635 (20130101) A61F 2002/7645 (20130101) A61F 2002/7665 (20130101) A61F 2002/7862 (20130101) A61F 2220/0075 (20130101) A61F 2250/008 (20130101) A61F 2250/0074 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2205/8256 (20130101) A61M 2205/8262 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 15/0009 (20130101) B25J 19/005 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 9/06 (20130101) F16D 27/01 (20130101) F16D 41/12 (20130101) F16D 41/105 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0045 (20130101) H02J 7/0048 (20200101) H02J 7/0068 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011516 | Shepherd et al. |
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APPLICANT(S) | Cornell University (Ithaca, New York) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Robert F. Shepherd (Ithaca, New York); James K. Min (Brooklyn, New York); Benjamin C. Mac Murray (Ithaca, New York) |
ABSTRACT | Foam-based pneumatic actuators can be formed in a state of mechanical compression prior to actuation. An actuator includes an elastomeric foam; a coating disposed on the elastomeric foam; and an elastomer seal disposed on the coating. The coating constrains the elastomeric foam and can be configured to break or fracture when the elastomeric foam inflates. The elastomer seal can be configured to be impermeable to the actuating fluid. Such a foam actuator can be used in a cardiac compression device. These foam actuators possess increased actuation deformation and an actuation exerted force for a given inflation pressure. A large deformation can be provided from materials having low ultimate strains. |
FILED | Monday, June 19, 2017 |
APPL NO | 16/310638 |
ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2481 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/06 (20130101) A61L 31/10 (20130101) A61L 31/146 (20130101) Original (OR) Class A61L 2420/02 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 60/43 (20210101) A61M 60/191 (20210101) A61M 60/289 (20210101) A61M 60/468 (20210101) A61M 60/839 (20210101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/042 (20130101) C08J 2400/26 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 5/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011759 | Tabor et al. |
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APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
INVENTOR(S) | Christopher E Tabor (Kettering, Ohio); Alexander M Watson (Kettering, Ohio); Alexander B Cook (Beavercreek, Ohio) |
ABSTRACT | An extrusion printing process for conductive materials and a conductive material extrusion system. The process includes attaching a counter-electrode to a first side of a substrate. A drive voltage is applied to the counter-electrode and to a conductive material to be extruded onto a second side of the substrate, opposite the first side. The conductive material is extruded onto the second side of the substrate while the drive voltage is being applied to the counter-electrode and conductive material. The conductive material is selected from a metal having a melting point ranging from about −20° C. to about 150° C. |
FILED | Thursday, January 17, 2019 |
APPL NO | 16/250693 |
ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 23/003 (20130101) Original (OR) Class Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/22 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/1275 (20130101) H05K 2203/0126 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011782 | Lazarus et al. |
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APPLICANT(S) | U.S. Army DEVCOM Army Research Laboratory (Adelphi, Maryland) |
ASSIGNEE(S) | The Unied States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Nathan S. Lazarus (Bear, Delaware); Gabriel L. Smith (Ellicott City, Maryland); Adam A. Wilson (Columbia, Maryland) |
ABSTRACT | A method and apparatus for using a laser to form and release an element of an actuator. The method comprising forming an actuator from sheet stock using a laser, where the actuator is three dimensional; releasing an element of the actuator from the sheet stock using the laser; and moving the released part relative to the sheet stock using laser ablation propulsion. |
FILED | Monday, February 27, 2023 |
APPL NO | 18/114679 |
ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/40 (20130101) Original (OR) Class B23K 2103/50 (20180801) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011868 | Baer et al. |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
INVENTOR(S) | Eric Baer (Cleveland Heights, Ohio); Andrew Olah (Spencer, Ohio); Cong Zhang (Shaker Heights, Ohio); Gary Wnek (Cleveland, Ohio); Nathan McMullen (Cleveland, Ohio); Chung-Fu Cheng (Aurora, Ohio) |
ABSTRACT | A method of producing high modulus and strength polymer materials includes compressive rolling a semicrystalline polymer material in at least two different axial directions of the material; and axially orienting at least a portion of the compressive rolled material to a draw ratio less than the ultimate elongation or the elongation % at break of the material. |
FILED | Wednesday, September 14, 2022 |
APPL NO | 17/944403 |
ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/003 (20130101) B29C 45/0001 (20130101) B29C 48/07 (20190201) B29C 48/0011 (20190201) B29C 48/022 (20190201) B29C 59/04 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/08 (20130101) B29K 2023/12 (20130101) B29K 2023/16 (20130101) B29K 2023/065 (20130101) B29K 2995/0051 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/731 (20130101) B29L 2031/768 (20130101) B29L 2031/4821 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/02 (20130101) C08K 2201/004 (20130101) C08K 2201/011 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012184 | Henry et al. |
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APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
INVENTOR(S) | Christopher P. Henry (Thousand Oaks, California); Walter S Wall (Calabasas, California); Carson R. White (Agoura Hills, California) |
ABSTRACT | A spar buoy for very low frequency (VLF) or low frequency (LF) transmission including a first portion of the spar buoy extending above a mean water line including a conductive structure including a coaxial feed, and an antenna coupled to the coaxial feed and extending above the conductive structure, and a second portion of the spar buoy below the mean water line including a transmitter coupled to the coaxial feed, an energy storage subsystem coupled to the transmitter and an electric power generation subsystem coupled to the energy storage subsystem. |
FILED | Friday, September 11, 2020 |
APPL NO | 17/018870 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 35/44 (20130101) Original (OR) Class B63B 2035/442 (20130101) Antennas, i.e Radio Aerials H01Q 1/04 (20130101) H01Q 1/30 (20130101) H01Q 1/34 (20130101) H01Q 9/36 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012187 | Bass |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jamie Bass (Evansville, Indiana) |
ABSTRACT | Provided is a maritime overboard locator system for use in locating and rescuing a person or asset that has fallen overboard into a body of water. The system includes a locator attached to a person or asset that is activated manually or automatically upon immersion in water. The apparatus emits light, sound, radio, or any combination thereof. The locator is detected by one or more detectors onboard a boat, ship, vessel, or structure. The detectors detect a unique signal that is assigned to each person/asset. Once detected, the detector sends an overboard alert and deploys an unmanned aerial or underwater drone. The drone can include an inflatable life preserver or life raft and a tether cord that helps the person to remain afloat until rescue can be accomplished. |
FILED | Thursday, March 18, 2021 |
APPL NO | 17/205325 |
ART UNIT | 2632 — Digital Communications |
CURRENT CPC | Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 9/01 (20130101) B63C 9/04 (20130101) B63C 9/0005 (20130101) Original (OR) Class B63C 9/26 (20130101) B63C 9/082 (20130101) B63C 2009/042 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012190 | Caldwell et al. |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Jesse T. Caldwell (Alpine, California); Brandon J. Wiedemeier (San Diego, California) |
ABSTRACT | A flange for a pressure vessel includes a rim, a sealing seat, and an undercut fillet. The rim has an annular surface for abutting an annular end of a cylindrical wall of the pressure vessel. The sealing seat has a cylindrical surface for abutting an inner surface of the cylindrical wall of the pressure vessel nearby the annular end. The undercut fillet is disposed between the rim and the sealing seat. A concave surface of the undercut fillet extends the annular surface of the rim radially inward and then curves back outward to intersect the cylindrical surface of the sealing seat. The undercut fillet of the flange helps distribute stress produced from a pressure differential between the inside and outside of the pressure vessel. |
FILED | Wednesday, August 25, 2021 |
APPL NO | 17/411259 |
ART UNIT | 3617 — Digital Communications |
CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/04 (20130101) Original (OR) Class B63G 2008/002 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012205 | Christensen et al. |
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APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
INVENTOR(S) | Kevin Thomas Christensen (Plano, Texas); Sang Gyun Park (Southlake, Texas) |
ABSTRACT | A flight control computer (FCC) may implement automatic rotor tilt control by gathering or receiving, as inputs, airspeed or a commanded airspeed for the aircraft, acceleration or a commanded acceleration for the aircraft, pitch attitude of the aircraft and pilot pitch bias commands for the aircraft, a rotor tilt angle, and/or the like. The FCC calculates, from the airspeed, the commanded airspeed, the acceleration, the commanded acceleration, the pitch attitude, the pilot pitch bias commands, and/or the like, a commanded rotor tilt angle for the aircraft. From the aircraft rotor tilt angle and the commanded rotor tilt angle, the FCC calculates a rotor tilt angle error for the aircraft, and from the rotor tilt angle error, calculates a rotor tilt rate command for the aircraft. The FCC outputs the resulting rotor tilt rate command to (an) aircraft flight control element actuator(s) to tilt the aircraft rotor. |
FILED | Thursday, December 23, 2021 |
APPL NO | 17/561195 |
ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeroplanes; Helicopters B64C 13/18 (20130101) B64C 13/22 (20130101) B64C 29/0033 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012336 | Tour et al. |
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APPLICANT(S) | William Marsh Rice University (Houston, Texas); B.G. Negev Technologies and Applications Ltd. at Ben-Gurion University (Beer Sheva, Israel) |
ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); B.G. NEGEV TECHNOLOGIES AND APPLICATIONS, LTD. AT BEN-GURION UNIVERSITY (Beer Sheva, Israel) |
INVENTOR(S) | James M. Tour (Bellaire, Texas); Yieu Chyan (Houston, Texas); Christopher John Arnusch (Midreshet Ben-Gurion, Israel); Swatantra Pratap Singh (Midreshet Ben-Gurion, Israel); Yilun Li (Sugar Land, Texas); Duy X. Luong (Houston, Texas); Carter Kittrell (Houston, Texas); Ruquan Ye (Houston, Texas); Jordan Miller (Houston, Texas); Ian Kinstlinger (Houston, Texas); Savannah Cofer (Gahanna, Ohio) |
ABSTRACT | Methods that expand the properties of laser-induced graphene (LIG) and the resulting LIG having the expanded properties. Methods of fabricating laser-induced graphene from materials, which range from natural, renewable precursors (such as cloth or paper) to high performance polymers (like Kevlar). With multiple lasing, however, highly conductive PEI-based LIG could be obtained using both multiple pass and defocus methods. The resulting laser-induced graphene can be used, inter alia, in electronic devices, as antifouling surfaces, in water treatment technology, in membranes, and in electronics on paper and food Such methods include fabrication of LIG in controlled atmospheres, such that, for example, superhydrophobic and superhydrophilic LIG surfaces can be obtained. Such methods further include fabricating laser-induced graphene by multiple lasing of carbon precursors. Such methods further include direct 3D printing of graphene materials from carbon precurors. Application of such LIG include oil/water separation, liquid or gas separations using polymer membranes, anti-icing, microsupercapacitors, supercapacitors, water splitting catalysts, sensors, and flexible electronics. |
FILED | Monday, November 01, 2021 |
APPL NO | 17/516430 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/01 (20130101) C01P 2002/82 (20130101) C01P 2004/03 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/005 (20130101) H01S 3/0007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012423 | Peterson et al. |
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APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Chemical Biological Center (Apg, Maryland) |
ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Gregory W. Peterson (Belcamp, Maryland); Thomas H. Epps, III (Newark, Delaware) |
ABSTRACT | A composition having the structure of formula I: [R—Ar—(COOH)2]x[Ar—(COOH)3]2-xM32+ (I) is provided where M is Mn, Cu, Co, Fe, Zn, Cd, Ni, or Pt; R is a bromine, nitro, a primary amine, C1-C4 alkyl secondary amine, C1-C4 alkyl oxy, Br—(C1-C4 alkyl), NO2—(C1-C4 alkyl), a mercaptan, and reaction products of any of the aforementioned with acyl chlorides of the formulas: CH3(CH2)mC(O)Cl, or CH3(CH(C1-C4 alkyl)CH2)mC(O)Cl, or CH3(CH2)m-Ph-(CH2)pC(O)Cl, where Ph is a C6 phenyl or C6 phenyl with one or more hydrogens replaced with F, C1-C4 fluoroalkyl, or C1-C4 perfluoroalkyl; m is independently in each occurrence an integer of 0 to 12 inclusive; p is an integer of 0 to 36 inclusive, to form an amide, a thioamide, or an ester; Ar is a 1,3,5-modified phenyl, and 1.4>x>0. A process of synthesis thereof and the use to chemically modify a gaseous reactant are also provided. |
FILED | Friday, September 30, 2022 |
APPL NO | 17/957234 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Separation B01D 53/58 (20130101) B01D 53/62 (20130101) B01D 67/0079 (20130101) B01D 69/12 (20130101) B01D 71/022 (20130101) B01D 71/82 (20130101) B01D 2257/93 (20130101) B01D 2257/406 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) B01D 2323/39 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012438 | Schlom et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Jeffrey Schlom (Potomac, Maryland); Claudia M. Palena (Potomac, Maryland) |
ABSTRACT | The invention provides Brachyury deletion mutant polypeptides, nucleic acids encoding the polypeptides, non-yeast vectors comprising the nucleic acids, non-yeast cells, and methods of use. |
FILED | Monday, June 14, 2021 |
APPL NO | 17/346452 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 38/193 (20130101) A61K 38/1709 (20130101) A61K 39/0011 (20130101) A61K 39/00117 (20180801) A61K 39/001152 (20180801) A61K 39/001182 (20180801) A61K 45/06 (20130101) A61K 2039/70 (20130101) A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4702 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/10043 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012455 | Dimitrov et al. |
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APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Dimiter S. Dimitrov (Pittsburgh, Pennsylvania); Weizao Chen (Frederick, Maryland); Terry J. Fry (Aurora, Colorado); Christopher Chien (Falls Church, Virginia) |
ABSTRACT | Human monoclonal antibodies that specifically bind Fms-like tyrosine kinase 3 (FLT3) are described. Chimeric antigen receptors (CARs) and other antibody conjugates that include the FLT3-specific monoclonal antibodies are also described. Methods for the diagnosis and treatment of FLT3-associated cancer, such as acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML), are further described. |
FILED | Thursday, January 06, 2022 |
APPL NO | 17/570248 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6849 (20170801) A61K 47/6929 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) A61P 35/04 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) C07K 16/468 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/577 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012463 | Ho et al. |
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FUNDED BY |
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APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Mitchell Ho (Urbana, Maryland); Nan Li (Laurel, Maryland); Bryan D. Fleming (Bethesda, Maryland) |
ABSTRACT | Monoclonal antibodies that bind glypican-2 (GPC2) with high affinity are described. Immunotoxins and chimeric antigen receptors (CARs) that include the disclosed antibodies or antigen-binding fragments thereof are further described. In some instances, the antibody or antigen-binding fragment is humanized. The disclosed GPC2-specific antibodies and conjugates can be used, for example, for the diagnosis or treatment of GPC2-positive cancers, including neuroblastoma, medulloblastoma and retinoblastoma. |
FILED | Tuesday, August 06, 2019 |
APPL NO | 17/266419 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6829 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 16/30 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5748 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012599 | Clarke et al. |
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FUNDED BY |
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APPLICANT(S) | CZ Biohub SF LLC (San Francisco, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | CZ Biohub SF, LLC (San Francisco, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Michael F. Clarke (Stanford, California); Neethan A. Lobo (Stanford, California); Maider Zabala Ugalde (Stanford, California); Jane Antony (Stanford, California) |
ABSTRACT | This disclosure provides data showing that LEFTY inhibits differentiation-promoting pathways such as BMP7/pSMAD5 in breast cancer cell lines, over and above its known role of inhibiting Nodal/pSMAD2. LEFTY competes with BMP7 to bind to its cell surface receptor BMPR2, leading to inhibition of pSMAD5. The LEFTY-BMPR2 interaction is dominant over BMP-BMPR2 in tumorigenic cells, resulting in diminished pSMAD status, whereas in non-tumorigenic cells, there is minimal LEFTY-BMPR2 interaction, increased BMP7-BMPR2 association, and elevated pSMAD. Compositions and methods for inducing or inhibiting expression and/or the activity of LEFTY and BMP proteins are described, which can be used in diagnosis and therapy of cancer and other conditions, and to promote proliferation of stem cells. |
FILED | Monday, April 15, 2019 |
APPL NO | 17/046276 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1808 (20130101) A61K 38/1841 (20130101) A61K 38/1875 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/22 (20130101) C07K 2317/24 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1136 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/122 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) G01N 33/57484 (20130101) G01N 2333/51 (20130101) G01N 2333/495 (20130101) G01N 2500/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012609 | Hashemi et al. |
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FUNDED BY |
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APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
INVENTOR(S) | Nicole Nastaran Hashemi (Ames, Iowa); Reza Montazami (Ames, Iowa); Marilyn Christine McNamara (Ames, Iowa); Jasmin Okuzono (Ames, Iowa) |
ABSTRACT | Various embodiments disclosed relate to conductive graphene matrix-encapsulated cells. A matrix-encapsulated cell includes an encapsulating polymer matrix including a biopolymer and graphene. The matrix-encapsulated cell also includes one or more of the cells encapsulated within the encapsulating polymer, wherein the graphene directly contacts at least some of the cells. The matrix encapsulating the one or more cells is electrically conductive. |
FILED | Tuesday, May 09, 2023 |
APPL NO | 18/195017 |
ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/19 (20170801) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012752 | Ford et al. |
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FUNDED BY |
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APPLICANT(S) | Hepburn and Sons LLC (Manassas, Virginia); Jaxon Engineering and Maintenance, Inc. (Colorado Springs, Colorado) |
ASSIGNEE(S) | |
INVENTOR(S) | Thomas Benjamin Ford (Midland City, Alabama); Matthew Janish (Eibert, Colorado) |
ABSTRACT | Electromagnetically shielded and self-supporting panels form a shielded enclosure. The use of prefabricated, shielded and self-supporting panels to construct an enclosure reduces the time and cost of constructing such an enclosure. |
FILED | Friday, June 25, 2021 |
APPL NO | 17/358710 |
ART UNIT | 3633 — Static Structures, Supports and Furniture |
CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/08 (20130101) E04B 1/92 (20130101) Original (OR) Class E04B 2001/925 (20130101) E04B 2103/06 (20130101) Structural Elements; Building Materials E04C 2/08 (20130101) E04C 2/46 (20130101) E04C 2/50 (20130101) E04C 2/322 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/72 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 9/0003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012801 | Judson et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
INVENTOR(S) | John S. Judson (Vicksburg, Mississippi); Jessica K. Vankirk (Vicksburg, Mississippi); David V. Senior (Vicksburg, Mississippi); Craig R. Ackerman (Gainesville, Virginia); Daniel Duke (Washington, District of Columbia) |
ABSTRACT | Blast, ballistic, and entry resistant operable window systems include a sliding exterior glazing panel assembly, a sliding interior glazing panel assembly, an exterior frame assembly that receives the sliding exterior glazing panel assembly, an interior frame assembly that receives the sliding interior glazing panel assembly, an exterior gasket for placement between the exterior frame assembly and the wall of the building, a central gasket for placement between the exterior frame assembly and the interior frame assembly, and an interior gasket for placement between the interior frame assembly and the wall of the building. Methods of installation in a wall of a building are also provided. |
FILED | Monday, September 30, 2019 |
APPL NO | 16/589116 |
ART UNIT | 3635 — Static Structures, Supports and Furniture |
CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 3/64 (20130101) E06B 3/2605 (20130101) E06B 3/4609 (20130101) E06B 3/5454 (20130101) E06B 5/11 (20130101) E06B 5/12 (20130101) Original (OR) Class E06B 5/106 (20130101) E06B 2003/2615 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012865 | Glavicic et al. |
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FUNDED BY |
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APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
INVENTOR(S) | Michael Glavicic (Avon, Indiana); Daniel E. Molnar, Jr. (Lebanon, Indiana); Matthew Jordan (Indianapolis, Indiana); Michael Meyer (Greenwood, Indiana) |
ABSTRACT | Methods for forming a blade for a gas turbine engine include altering the crystallographic texture of the blade in a discrete region relative to the surrounding locations of the blade to minimize flutter and/or mistune the blade by changing the natural frequency response of at least one mode of the blade. |
FILED | Wednesday, December 29, 2021 |
APPL NO | 17/564455 |
ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 9/0068 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/183 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/16 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2240/304 (20130101) F05D 2260/961 (20130101) F05D 2300/701 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012895 | Rutledge et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
INVENTOR(S) | James Rutledge (Fairborn, Ohio); Matthew Fuqua (Oakwood, Ohio); Carol Bryant (Fairborn, Ohio) |
ABSTRACT | A method and system for cooling an engine and/or vehicle using energy separation is disclosed herein. An energy separation device is operable for separating a compressed gaseous coolant stream into a first relatively cooler coolant flow stream and a second relatively hotter coolant flow stream. The relative cooler coolant flow stream is directed to a first region requiring increased cooling and the relative hotter coolant flow stream is directed to a second region requiring lower cooling than the first region in the engine or vehicle. |
FILED | Tuesday, August 02, 2022 |
APPL NO | 17/879016 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/202 (20130101) F05D 2260/209 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 2900/03041 (20130101) F23R 2900/03042 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012981 | Aksak et al. |
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FUNDED BY |
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APPLICANT(S) | TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas) |
ASSIGNEE(S) | TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas) |
INVENTOR(S) | Burak Aksak (Lubbock, Texas); Luciano Castillo (Carmel, Indiana); Humberto Bocanegra Evans (Lubbock, Texas) |
ABSTRACT | A coating apparatus for the reduction of aerodynamic noise and vibrations. The coating apparatus is configured to include a group of fibrillar structures, wherein each fibrillar structure is configured with a diverging tip so that the coating reduces the size of and shifts downstream, a separation bubble, and modulates large-scale recirculating motion. Each fibrillar structure can be configured as a cylindrical micropillar. The group of fibrillar structures can be configured as a group of uniformly distributed cylindrical micropillars (e.g., one or more micropillar arrays). The surface coating is effective in reducing the separation bubble and displacing the separation bubble downstream. The coating facilitates a reduction in noise (e.g., aerodynamic noise) and vibrations due to the reduction in the size of the separation bubble. |
FILED | Friday, October 09, 2020 |
APPL NO | 17/067464 |
ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeroplanes; Helicopters B64C 21/10 (20130101) B64C 2230/26 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/0035 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013043 | Chua et al. |
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FUNDED BY |
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APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
ASSIGNEE(S) | Xerox Corporation (Norwalk, Connecticut) |
INVENTOR(S) | Christopher L. Chua (San Jose, California); Julie Ann Bert (Palo Alto, California); Steven Neltner (San Carlos, California); Emily Coker (Oakland, California) |
ABSTRACT | An apparatus comprises a frangible structure coupled or integral to at least a portion of the apparatus and a triggerable mechanism disposed at or proximate the frangible structure. The triggerable mechanism is configured to break the frangible structure in response to a trigger signal. A containment structure is disposed on or over at least a portion of the frangible structure. The containment structure is configured to allow at least the portion of the frangible structure to deform or change shape in response to breaking of the frangible structure while keeping substantially all fragments of at least the portion of the broken frangible structure together. |
FILED | Monday, December 21, 2020 |
APPL NO | 17/129344 |
ART UNIT | 3753 — Fluid Handling and Dispensing |
CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 22/18 (20130101) Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 9/00 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 13/04 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 137/1699 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013194 | Retersdorf |
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FUNDED BY |
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APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
INVENTOR(S) | Alan Retersdorf (Avon, Connecticut) |
ABSTRACT | A hot layer adapted for use in an asymmetric cross counter flow heat exchanger core that includes a number of alternating hot and cold layers, a hot inlet tent configured to receive a hot inlet flow and defining a hot inlet tent width, and a hot outlet tent configured to discharge a hot outlet flow and defining a hot outlet tent width. A hot inlet closure bar is located adjacent to the hot inlet tent, a hot outlet closure bar is located adjacent to the hot outlet tent, and two hot side closure bars are each located adjacent to respective corresponding inlet and outlet hot fins. An angle between the inlet fin direction and the middle fin direction ranges from 5-175 degrees, and the hot inlet tent width is less than the hot outlet tent width. |
FILED | Monday, April 29, 2019 |
APPL NO | 16/397772 |
ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 9/0068 (20130101) F28D 9/0093 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/04 (20130101) Original (OR) Class F28F 2250/108 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013202 | Main |
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FUNDED BY |
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APPLICANT(S) | Richard E. Main (Fredericksburg, Virginia) |
ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
INVENTOR(S) | Richard E. Main (Fredericksburg, Virginia) |
ABSTRACT | An instrumentation article is provided for removably attaching to an ammunition round in a gun chamber and connecting to a cable that extends through the chamber. The cable provides tensile pull and signal communication through the chamber. The article has a longitudinal axis that corresponds to the chamber. The article includes a cap structure, an electronics package, a grip assembly, a lock mechanism and a release device. The cap structure connects to the cable. The electronics package provides electrical power and attaches to the cap structure for communication with the round. The grip assembly attaches to the round. The release device connects the electronics package to the lock mechanism. The lock mechanism is disposed between the release device and the grip assembly and rotates in first and second directions along the axis. The lock mechanism latches the claw assembly to the round by manual rotation in the first direction. The lock mechanism withdraws the grip assembly from the round by automatic rotation in the second direction. The release device unlatches the lock mechanism. |
FILED | Thursday, September 02, 2021 |
APPL NO | 17/465552 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 7/042 (20130101) Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 31/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013572 | Vakoc et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Benjamin Vakoc (Arlington, Massachusetts); Meena Siddiqui (Boston, Massachusetts) |
ABSTRACT | Exemplary apparatus can be provided which can include a laser arrangement that is configured to provide a laser radiation, and including an optical cavity. The optical cavity can include a dispersive optical waveguide first arrangement having first and second sides, and which is configured to (i) receive at least one first electro-magnetic radiation at the first side so as to provide at least one second electro-magnetic radiation, and (ii) to receive at least one third electro-magnetic radiation at the second side so as to provide at least one fourth electro-magnetic radiation. The first and second sides are different from one another, and the second and third radiations are related to one another. The optical cavity can also include an active optical modulator second arrangement which can be configured to receive and modulate the fourth radiation so as to provide the first electro-magnetic radiation to the first arrangement. The laser radiation can be associated with at least one of the first, second, third or fourth radiations. |
FILED | Wednesday, March 30, 2022 |
APPL NO | 17/708143 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/6826 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02091 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/32 (20130101) Optical Elements, Systems, or Apparatus G02B 6/2932 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/106 (20130101) H01S 3/0675 (20130101) H01S 3/1062 (20130101) H01S 3/06791 (20130101) H01S 3/08086 (20130101) Coding; Decoding; Code Conversion in General H03M 1/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014246 | Bhaskar et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Mihir Keshav Bhaskar (Cambridge, Massachusetts); Denis D. Sukachev (Cambridge, Massachusetts); Christian Thieu Nguyen (Cambridge, Massachusetts); Bartholomeus Machielse (Cambridge, Massachusetts); David S. Levonian (Cambridge, Massachusetts); Ralf Riedinger (Cambridge, Massachusetts); Mikhail D. Lukin (Cambridge, Massachusetts); Marko Loncar (Cambridge, Massachusetts) |
ABSTRACT | Systems and methods are disclosed for making a quantum network node. A plurality of scoring function F values are calculated for an array of at least two photonic crystal cavity unit cells, each having a lattice constant a and a hole having a length Hx and a width Hy. A value of a, a value of Hx, and a value of Hy are selected for which a scoring function value is at a maximum. A waveguide region and the array of at least two photonic crystal cavity unit cells based on the selected values are formed on a substrate. At least one ion between a first photonic crystal cavity unit cell and a second photonic crystal cavity unit cell are implanted and annealed into a quantum defect. A coplanar microwave waveguide is formed on the substrate in proximity to the array of at least two photonic crystal cavity unit cells. |
FILED | Thursday, July 16, 2020 |
APPL NO | 17/623757 |
ART UNIT | 2634 — Digital Communications |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 6/1225 (20130101) Computer Systems Based on Specific Computational Models G06N 10/70 (20220101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014247 | Seif Tabrizi et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); Government of the United States of America, as Represented by the Secretary of Commerce (Gaithersburg, Maryland) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); Government of the United States of America, As Represented by the Secretary of Commerce (Gaithersburg, Maryland) |
INVENTOR(S) | Seyed Alireza Seif Tabrizi (Adelphi, Maryland); Mohammad Hafezi (Washington, District of Columbia); Yi-Kai Liu (Gaithersburg, Maryland) |
ABSTRACT | A method for detecting a two-qubit correlated dephasing error includes accessing a signal of a quantum system, where the quantum system includes a plurality of qubits. Every qubit has a nonzero rate of dephasing and some qubits have a nonzero rate of correlated dephasing. The signal further includes information about a matrix that includes diagonal elements and off-diagonal elements. The off-diagonal elements of the matrix are 2s-sparse. The method further includes performing randomized measurements of the off-diagonal elements of the matrix and recovering the matrix based on a direct measurement of the diagonal elements of the matrix. |
FILED | Friday, May 13, 2022 |
APPL NO | 17/743850 |
ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/70 (20220101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014488 | Madabhushi et al. |
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FUNDED BY |
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APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by the Department of Veteran Affairs (Washington, District of Columbia); UH Cleveland Medical Center (Cleveland, Ohio) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); UH Cleveland Medical Center (Cleveland, Ohio); The United States Government as Represente (Washington, District of Columbia) |
INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Neeraj Kumar (Cleveland Heights, Ohio); Joseph E. Willis (Shaker Heights, Ohio) |
ABSTRACT | Embodiments discussed herein facilitate determination of cancer stages based at least in part on shape, size, and/or texture features of cancer nuclei. One example embodiment is a method, comprising: accessing at least a portion of a digital whole slide image (WSI) comprising a tumor; segmenting (e.g., via a first deep learning model) the tumor on the at least the portion of the digital WSI; segmenting (e.g., via a second deep learning model) cancer nuclei in the segmented tumor; extracting one or more features from the segmented cancer nuclei; providing the one or more features extracted from the segmented cancer nuclei to a trained machine learning model; and receiving, from the machine learning model, an indication of a cancer stage of the tumor. |
FILED | Monday, January 04, 2021 |
APPL NO | 17/140586 |
ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/41 (20170101) G06T 7/62 (20170101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) G06T 2207/30028 (20130101) G06T 2207/30081 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 70/60 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014609 | Stone et al. |
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FUNDED BY |
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APPLICANT(S) | APG Cash Drawer, LLC (Fridley, Minnesota) |
ASSIGNEE(S) | APG Cash Drawer, LLC (Fridley, Minnesota) |
INVENTOR(S) | Robert Hamilton Stone (Woodstock, Georgia); Scott Benjamin Johnson (Minneapolis, Minnesota); Nicholas Edward Maffey (Atlanta, Georgia); Russell Joseph Kroll (Atlanta, Georgia) |
ABSTRACT | A cashdrawer exoskeleton system is disclosed. The system includes a modular base piece with an integrated fastener configured to facilitate a coupling to a cash drawer. An aperture is formed through the top surface of the modular base piece and leads to an area where the cash drawer is positioned when the modular base piece is coupled to the cash drawer utilizing the integrated fastener. At least one spacer is then configured to facilitate creation of a gap between the modular base piece and the cash drawer when the modular base piece is coupled to the cash drawer utilizing the integrated fastener. |
FILED | Wednesday, October 19, 2022 |
APPL NO | 17/969093 |
ART UNIT | 2876 — Optics |
CURRENT CPC | Registering the Receipt of Cash, Valuables, or Tokens G07G 1/0027 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014885 | Huang et al. |
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FUNDED BY |
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APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
ASSIGNEE(S) | NUtech Ventures, Inc. (Lincoln, Nebraska) |
INVENTOR(S) | Jinsong Huang (Chapel Hill, North Carolina); Wuqiang Wu (Chapel Hill, North Carolina) |
ABSTRACT | A method of forming a photoactive device includes steps of: forming a photoactive layer, the photoactive layer comprising a perovskite material and a dopant; wherein the photoactive device comprises a positive electrode and a negative electrode; wherein said photoactive layer is directly or indirectly in electronic communication with the positive electrode and directly or indirectly in electronic communication with the negative electrode; and wherein the photoactive device is free of a hole transport layer between the photoactive layer and the positive electrode. |
FILED | Wednesday, April 24, 2019 |
APPL NO | 16/393111 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2059 (20130101) Original (OR) Class Organic electric solid-state devices H10K 71/15 (20230201) H10K 71/30 (20230201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014915 | Ramsey et al. |
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FUNDED BY |
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APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
INVENTOR(S) | John Michael Ramsey (Chapel Hill, North Carolina); Andrew Hampton (Auburn, Alabama); Kevin Schultze (Chapel Hill, North Carolina) |
ABSTRACT | A miniature electrode apparatus is disclosed for trapping charged particles, the apparatus includes, along a longitudinal direction, a first end cap electrode, a central electrode having an aperture, and a second end cap electrode. The aperture is elongated in the lateral plane and extends through the central electrode along the longitudinal direction and the central electrode surrounds the aperture in a lateral plane perpendicular to the longitudinal direction to define a transverse cavity for trapping charged particles. Electric fields can be applied in a y-direction of the lateral plane across one or more planes perpendicular to the longitudinal axis to translocate and/or manipulate ion trajectories. |
FILED | Monday, March 01, 2021 |
APPL NO | 17/188215 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) H01J 49/0027 (20130101) H01J 49/065 (20130101) Original (OR) Class H01J 49/424 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015093 | Guyot-Sionnest et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
INVENTOR(S) | Philippe Guyot-Sionnest (Chicago, Illinois); Xin Tang (Chicago, Illinois); Matthew M. Ackerman (Chicago, Illinois) |
ABSTRACT | Photodetectors based on colloidal quantum dots and methods of making the photodetectors are provided. Also provided are methods for doping films of colloidal quantum dots via a solid-state cation exchange method. The photodetectors include multi-band photodetectors composed of two or more rectifying photodiodes stacked in aback-to-back configuration. The doping methods rely on a solid-state cation exchange that employs sacrificial semiconductor nanoparticles as a dopant source for a film of colloidal quantum dots. |
FILED | Friday, January 31, 2020 |
APPL NO | 17/422973 |
ART UNIT | 2821 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14652 (20130101) H01L 31/1013 (20130101) H01L 31/1828 (20130101) H01L 31/035218 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015388 | Hickle |
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FUNDED BY |
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APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | Mark D. Hickle (Merrimack, New Hampshire) |
ABSTRACT | Techniques are provided for a broadband microwave/millimeter-wave balanced-to-unbalanced transformer (balun). A balun implementing the techniques according to an embodiment includes a first impedance matching network configured to reduce insertion and return losses of a single-ended signal at a first port of the balun. The balun also includes a first planar bifilar coupled transmission line coupled to the first impedance matching network and configured to transform the single-ended signal into a differential signal. The balun further includes a second planar bifilar coupled transmission line coupled to the first bifilar coupled transmission line and configured to compensate for amplitude and phase imbalance induced on the differential signal by the first bifilar coupled transmission line. The balun further includes a second impedance matching network coupled to both planar bifilar coupled transmission lines and configured to reduce insertion and return losses of the differential signal at second and third ports of the balun. |
FILED | Friday, May 28, 2021 |
APPL NO | 17/333163 |
ART UNIT | 2842 — Electrical Circuits and Systems |
CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 5/16 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/42 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015424 | Imani |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Mohsen Imani (Irvine, California) |
ABSTRACT | Disclosed is a network-based hyperdimensional system having an encoder configured to receive input data and encode the input data using hyperdimensional computing to generate a hypervector having encoded data bits that represent the input data. The network-based hyperdimensional system further includes a decoder configured to receive the encoded data bits, decode the encoded data bits, and reconstruct the input data from the decoded data bits. In some embodiments, the encoder is configured for direct hyperdimensional learning on transmitted data with no need for data decoding by the decoder. |
FILED | Thursday, August 25, 2022 |
APPL NO | 17/895177 |
ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/1108 (20130101) Original (OR) Class H03M 13/1128 (20130101) H03M 13/6312 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015542 | Lin et al. |
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FUNDED BY |
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APPLICANT(S) | BAE Systems Information and Electronic Systems Integration, Inc. (Nashau, New Hampshire) |
ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
INVENTOR(S) | Clifton A. Lin (Arlington, Massachusetts); Hema A. Retty (Jersey City, New Jersey) |
ABSTRACT | A dynamic controlling framework that is adapted to dynamically optimize existing routing decisions in an optimized link state routing (OLSR) platform to favor higher-bandwidth, lower-latency links in the active link database. The dynamic controlling framework includes a link probing tool that is in communication with OLSR platform where the link probing tool is adapted to dynamically measure estimated bandwidth, latency scores, or both estimated bandwidth and latency scores of active links in the active link database of the OLSR platform. The dynamic controlling framework includes a plug-in framework that is in communication with the OLSR platform and the link probing tool where the plugin framework is adapted to receive at least one link quality multiplier (LQM) metric computed by the link probing tool and to combine the at least one LQM metric with the OLSR platform's existing link quality (LQ) metric for enhancing route selection by the OLSR platform. |
FILED | Monday, December 20, 2021 |
APPL NO | 17/555819 |
ART UNIT | 2447 — Computer Networks |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/12 (20130101) H04L 43/0864 (20130101) H04L 45/22 (20130101) H04L 45/42 (20130101) H04L 45/123 (20130101) Original (OR) Class H04L 45/125 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015824 | Fleizach et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Gregory Knowles Fleizach (San Diego, California); Nicholas T. Johnson (Pensacola, Florida); Mohamed Chergui (San Diego, California); Christopher Lichtenberg (Carlsbad, California); Michael P. Civerolo (San Diego, California) |
ABSTRACT | An apparatus for passive coherent location includes a forecaster, an evaluator, a receiver, and a correlator. The forecaster generates a prediction of a radio-frequency signal transmitted from an antenna of a broadcasting service. The evaluator generates an effectiveness metric from the prediction of the radio-frequency signal. The receiver receives the radio-frequency signal that an object reflects from the antenna to the receiver. The correlator determines, from the radio-frequency signal reflected from the object as received at the receiver, an ambiguity function having a maximum at a temporal offset and a Doppler shift. The temporal offset and the Doppler shift at the maximum partially determine at least a position of the object. The apparatus optionally includes a selector for tuning the receiver to the radio-frequency signal in response to the effectiveness metric. |
FILED | Friday, March 19, 2021 |
APPL NO | 17/207402 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/00 (20130101) G01S 13/003 (20130101) G01S 13/58 (20130101) G01S 13/86 (20130101) Pictorial Communication, e.g Television H04N 21/458 (20130101) Original (OR) Class H04N 21/466 (20130101) H04N 21/4524 (20130101) H04N 21/6125 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015992 | Sparr et al. |
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FUNDED BY |
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APPLICANT(S) | SRI International (Menlo Park, California) |
ASSIGNEE(S) | SRI International (Menlo Park, California) |
INVENTOR(S) | Robert H. Sparr (San Carlos, California); Jesse Wodin (Denver, Colorado); Justin D. Landrum (San Francisco, California); Joseph M. Strus (Redwood City, California); Boskin Erkocevic (Superior, Colorado); Jacob M. Cooper (Santa Clara, California); David Watt (Superior, Colorado); Joshua A. Arndt (Great Mills, Maryland) |
ABSTRACT | Systems and methods for clock synchronization are disclosed. A client synchronization system (CSS) may transmit RF pulses to a server CSS over micrometeorite ionization trail (MMIT) channels, and may receive RF pulses from the server CSS over MMIT channels, each received RF pulse following transmitted RF pulse. The client CSS may receive from the server CSS over MMIT channels measurement data including pulse arrival times at the server CSS. The measurement and transmission data may be correlated to identify RF-pulse pairs, each pairing a transmitted RF pulse received by the server CSS with a received RF pulse received from the server CSS, both over the same MMIT. TWTT analysis may be applied to timing data the pairs to compute time offsets between a client clock and a server clock. An analytical model of clock drift may be applied to the offsets to synchronize the client clock to the server clock. |
FILED | Wednesday, June 08, 2022 |
APPL NO | 17/835148 |
ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Transmission H04B 7/145 (20130101) Wireless Communication Networks H04W 56/005 (20130101) Original (OR) Class H04W 56/0015 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12016107 | Dobie et al. |
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FUNDED BY |
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APPLICANT(S) | Texas Research International, Inc (Austin, Texas) |
ASSIGNEE(S) | TEXAS RESEARCH INTERNATIONAL, INC. (Austin, Texas); US GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (Natick, Massachusetts) |
INVENTOR(S) | Michael Jay Dobie (Double Oak, Texas); Anthony Patti (Wakefield, Massachusetts); Robert Philip Brushaber (Austin, Texas); Frank Thomas Zeller (Dripping Springs, Texas); Neal S. Cooper (N. Richland Hills, Texas) |
ABSTRACT | A continuous mode conveyor cooking appliance utilizing hot air jet impingement and microwave energy for cooking prepared foods. The approach envisions a central microwave unit with a hot air jet impingement oven unit on each side of the microwave section and a conveyor system to carry the food items completely through the appliance from one end to the other and with the two hot air jet impingement ovens equipped with a designed combination of hot air jet impingement jets and solid pins to act as a microwave attenuation system to reduce microwave exposure to cooking personnel to completely safe levels. |
FILED | Friday, March 19, 2021 |
APPL NO | 17/207532 |
ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Bakers\' Ovens; Machines or Equipment for Baking A21B 1/245 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 5/15 (20160801) Kitchen Equipment; Coffee Mills; Spice Mills; Apparatus for Making Beverages A47J 37/045 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/76 (20130101) H05B 6/647 (20130101) Original (OR) Class H05B 6/707 (20130101) H05B 6/763 (20130101) H05B 6/782 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
US 12011151 | Gittard et al. |
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FUNDED BY |
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APPLICANT(S) | Muffin Incorporated (West Lafayette, Indiana); National Institutes of Health, an Agency of the Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | Muffin Incorporated (West Lafayette, Indiana); THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Shaun Davis Gittard (Winston-Salem, North Carolina); Gregory James Hardy (Asheville, North Carolina); John C. Sigmon, Jr. (Winston-Salem, North Carolina); Jeremy T. Newkirk (West Lafayette, Indiana); William J. Havel (West Lafayette, Indiana); Neal E. Fearnot (West Lafayette, Indiana); Toby Rogers (Washington, District of Columbia); Kanishka Ratnayaka (Bethesda, Maryland); Robert L. Lederman (Chevy Chase, Maryland) |
ABSTRACT | Among other things, there is disclosed structure and methods for maintaining access to a location in the body while reducing or eliminating the potential for pulling an access device (e.g. a catheter) back through an opening. An introducer sheath includes a distal indented portion and a balloon, so that once placed in a desired location through tissue, the balloon can be inflated to anchor the sheath against retraction. In particular embodiments, structure and methods for accessing the pericardial cavity via the right atrial appendage are shown. |
FILED | Monday, July 26, 2021 |
APPL NO | 17/385230 |
ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0218 (20130101) Original (OR) Class A61B 90/39 (20160201) A61B 2017/0225 (20130101) A61B 2017/0237 (20130101) A61B 2017/00247 (20130101) A61B 2017/00557 (20130101) A61B 2017/00845 (20130101) A61B 2017/00955 (20130101) A61B 2017/3486 (20130101) A61B 2090/3925 (20160201) A61B 2090/3966 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 25/10 (20130101) A61M 25/0041 (20130101) A61M 25/0045 (20130101) A61M 25/0052 (20130101) A61M 25/0054 (20130101) A61M 25/0108 (20130101) A61M 25/0662 (20130101) A61M 2025/0047 (20130101) A61M 2025/1079 (20130101) A61M 2025/1093 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011248 | Miyaoka et al. |
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FUNDED BY |
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APPLICANT(S) | University of Washington (Seattle, Washington) |
ASSIGNEE(S) | University of Washington (Seattle, Washington) |
INVENTOR(S) | Robert S. Miyaoka (Seattle, Washington); Hubert Vesselle (Seattle, Washington); Robert Stewart (Seattle, Washington); Robert L. Harrison (Seattle, Washington); Larry A. Pierce, II (Seattle, Washington) |
ABSTRACT | A garment for detecting radiation washout (e.g., radioactivity concentrations) in organs includes a covering that wraps around and is secured to the body. The covering permits positron emission tomography-computed tomography (PET/CT) imaging of the body through the covering. The garment includes guides formed from a material that is visible in a computed tomography (CT) image of the garment, such that the guides are visible in CT images of user organs that the garment overlies. A plurality of radiation detectors are attached to the covering in a configuration customized for the body. A wiring system connects the plurality of radiation detectors to a power and data control system that is configured to transmit data from the garment to a remote service provider. |
FILED | Friday, May 10, 2019 |
APPL NO | 17/045112 |
ART UNIT | 3797 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/0024 (20130101) Original (OR) Class A61B 5/0033 (20130101) A61B 5/066 (20130101) A61B 5/6805 (20130101) A61B 6/4266 (20130101) Measurement of Nuclear or X-radiation G01T 1/02 (20130101) G01T 1/29 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011254 | Tokuda et al. |
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FUNDED BY |
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APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | The Brigham and Women's Hospital (Boston, Massachusetts) |
INVENTOR(S) | Junichi Tokuda (Westwood, Massachusetts); Qun Wang (Beijing, China PRC); Kemal Tuncali (Newton, Massachusetts); Ravi Teja Seethamraju (Malden, Massachusetts); Clare M. Tempany (Charlestown, Massachusetts); Ehud J. Schmidt (Towson, Maryland) |
ABSTRACT | The present disclosure is directed to systems and methods for generating images using short tau inversion recovery, ultrashort echo time (STIR-UTE) MRI sequences. The STIR-UTE MRI sequences can be used to generate images that can differentiate between regions that are at temperatures that are either lethal or non-lethal to cell life. Thus, these sequences can be beneficial for implementations such as in monitoring cryoablation procedures. |
FILED | Wednesday, November 18, 2020 |
APPL NO | 16/951074 |
ART UNIT | 3798 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/06 (20130101) A61B 5/055 (20130101) Original (OR) Class A61B 5/746 (20130101) A61B 90/37 (20160201) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/5615 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011257 | Matijevich et al. |
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FUNDED BY |
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APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
INVENTOR(S) | Emily Matijevich (Nashville, Tennessee); Leon Scott (Nashville, Tennessee); Karl Zelik (Nashville, Tennessee) |
ABSTRACT | A wearable device operably worn by a user for monitoring musculoskeletal loading on structure inside the body of the user includes a plurality of sensors, each sensor operably worn by the user at a predetermined location and configured to detect information about a biomechanical activity of musculoskeletal tissues, a limb segment orientation, and/or a loading magnitude or location thereon; and a processing unit in communication with the plurality of sensors and configured to process the detected information by the plurality of sensors to estimate the musculoskeletal loading, and communicate the estimated musculoskeletal loading to the user and/or a party of interest. |
FILED | Tuesday, April 30, 2019 |
APPL NO | 17/051218 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/11 (20130101) Original (OR) Class A61B 5/296 (20210101) A61B 5/746 (20130101) A61B 5/4509 (20130101) A61B 5/4538 (20130101) A61B 5/4806 (20130101) A61B 5/6801 (20130101) A61B 5/6898 (20130101) A61B 5/7405 (20130101) A61B 5/7435 (20130101) A61B 5/7455 (20130101) A61B 2562/0219 (20130101) A61B 2562/0247 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011291 | Howard et al. |
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FUNDED BY |
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APPLICANT(S) | GEORGE MASON RESEARCH FOUNDATION, INC. (Fairfax, Virginia) |
ASSIGNEE(S) | GEORGE MASON RESEARCH FOUNDATION, INC. (Fairfax, Virginia) |
INVENTOR(S) | Marissa A. Howard (Richmond, Virginia); Lance A. Liotta (Bethesda, Maryland); Rachel Naidich (Fairfax, Virginia); Matthew Luu Trang (Nokesville, Virginia); Ish Sethi (Chantilly, Virginia); Rebecca Woodhouse (Oakton, Virginia); Kshamata Neupane (Haymarket, Virginia) |
ABSTRACT | A wearable device measures, tracks, and monitors a wearer's physical physiological conditions during a rehabilitation period. Metrics such as temperature, patellar shifting, limb circumference, and acceleration may be collected. Changes in monitored conditions may be assessed for detecting medical abnormalities which require specialized attention, including for example embolisms or infections. A networked communication system and various user interfaces may be used for medical support personnel and patients alike to stay updated with the patient's rehabilitation progress and to make adjustments in a patient's individual rehabilitation program. |
FILED | Friday, February 18, 2022 |
APPL NO | 17/651661 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/015 (20130101) A61B 5/0024 (20130101) A61B 5/0048 (20130101) A61B 5/0053 (20130101) A61B 5/112 (20130101) A61B 5/746 (20130101) A61B 5/1107 (20130101) A61B 5/1114 (20130101) A61B 5/1126 (20130101) A61B 5/4519 (20130101) A61B 5/4528 (20130101) A61B 5/4585 (20130101) A61B 5/4848 (20130101) A61B 5/6824 (20130101) A61B 5/6828 (20130101) Original (OR) Class A61B 5/6829 (20130101) A61B 5/7275 (20130101) A61B 5/7465 (20130101) A61B 2503/08 (20130101) A61B 2503/10 (20130101) A61B 2505/09 (20130101) A61B 2562/0219 (20130101) A61B 2562/0247 (20130101) A61B 2562/0261 (20130101) A61B 2562/0271 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 2230/08 (20130101) A61H 2230/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011297 | Mukkamala et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
INVENTOR(S) | Ramakrishna Mukkamala (Okemos, Michigan); Anand Chandrasekhar (East Lansing, Michigan); Keerthana Natarajan (East Lansing, Michigan); Mohammad Yavarimanesh (Lansing, Michigan) |
ABSTRACT | Various systems, techniques, and embodiments are disclosed for implementing a blood-pressure measurement method that does not require specialized equipment (such as inflatable blood pressure cuffs). The measurement can be taken from arterial locations within a user's finger, via the standard equipment and features of many widely-available consumer mobile devices. Such devices can be programmed to accurately and easily guide a user to press her finger on the screen of a device at a precise location, so that an accurate measurement can be taken. For example, guidance visualizations on a screen (such as finger silhouettes and animations) can be employed on the same screen on which a user presses her finger. Pressure sensitivity and optical camera readings are then used to calculate blood pressure for the user. |
FILED | Friday, June 28, 2019 |
APPL NO | 17/256609 |
ART UNIT | 3798 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0295 (20130101) A61B 5/743 (20130101) A61B 5/1075 (20130101) A61B 5/02225 (20130101) A61B 5/6898 (20130101) Original (OR) Class A61B 2562/0247 (20130101) A61B 2562/0261 (20130101) Electric Digital Data Processing G06F 3/044 (20130101) Wireless Communication Networks H04W 88/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011302 | Fairchild et al. |
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FUNDED BY |
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APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
INVENTOR(S) | Karen D. Fairchild (Charlottesville, Virginia); Douglas E. Lake (Charlottesville, Virginia); Brynne Sullivan (Charlottesville, Virginia) |
ABSTRACT | A method and system for generating pulse oximetry predictive scores (POPS) for predicting adverse outcomes in preterm infants. The method comprising generating a POPS via a predictive algorithm which incorporates cross-correlation of heart rate and SpO2 calculated on archived pulse oximetry data of multiple preterm infants, and predicting a pathology of a preterm infant based on the generated POPS, wherein the pathology is intraventricular hemorrhage, late-onset sepsis, necrotizing enterocolitis, bronchopulmonary dysplasia, or retinopathy of prematurity, and informing a user of an opportunity to: identify the preterm infant as a highest risk infant and perform additional surveillance of or therapeutic intervention on the preterm infant, identify the preterm infant for participation in a clinical trial based on a risk profile associated with the POPS, and treat said preterm infant for the pathology. |
FILED | Monday, December 21, 2020 |
APPL NO | 17/129695 |
ART UNIT | 3796 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/48 (20130101) A61B 5/1455 (20130101) A61B 5/7275 (20130101) Original (OR) Class A61B 5/14551 (20130101) A61B 2503/045 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 2230/205 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 15/00 (20180101) G16H 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011426 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
INVENTOR(S) | Wei Li (Bethesda, Maryland); Tantai Zhao (Hunan, China PRC); Jingxing Ou (Guangdong, China PRC) |
ABSTRACT | Methods are disclosed for treating and/or preventing a neurological condition, such as neural injury or neurological disorder, in a subject through metabolic regulation of mitochondria using compounds that are natural metabolites, metabolite analogs, or derivatives of natural metabolites to modulate biochemical pathways comprising succinate and/or succinate dehydrogenase, thereby reducing microglial cell and/or astrocyte activation. Compounds and related formulations are also provided to modulate the biochemical pathways comprising succinate and/or succinate dehydrogenase for reducing or inhibiting microglial cell and/or astrocyte activation. |
FILED | Wednesday, August 21, 2019 |
APPL NO | 17/268203 |
ART UNIT | 1622 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/23 (20130101) A61K 31/194 (20130101) Original (OR) Class Enzymes C12Y 103/05001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011432 | Dealwis |
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FUNDED BY |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
INVENTOR(S) | Chris Dealwis (Highland Heights, Ohio) |
ABSTRACT | A method of modulating ribonucleotide reductase activity in a neoplastic cell includes administering to the cell an amount of a hydrazone or hydrazine ribonucleotide reductase modulator (RRmod), the amount being effective to inhibit neoplastic cell growth. |
FILED | Thursday, July 18, 2019 |
APPL NO | 17/260998 |
ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/15 (20130101) A61K 31/52 (20130101) A61K 31/341 (20130101) A61K 31/381 (20130101) A61K 31/404 (20130101) Original (OR) Class A61K 31/426 (20130101) A61K 31/4406 (20130101) A61K 31/4412 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011452 | Falk et al. |
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FUNDED BY |
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APPLICANT(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania) |
INVENTOR(S) | Marni J. Falk (Philadelphia, Pennsylvania); Eiko Nakamaru-Ogiso (Philadelphia, Pennsylvania) |
ABSTRACT | Compositions and methods for treatment of mitochondrial respiratory chain dysfunction and other mitochondrial disorders are provided. Also disclosed are a number of screening assays having utility for the identification of agents which modulate the phenotype associated with mitochondrial respiratory chain dysfunction. |
FILED | Thursday, June 27, 2019 |
APPL NO | 17/256406 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/10 (20130101) A61K 31/145 (20130101) A61K 31/198 (20130101) A61K 31/455 (20130101) A61K 31/7004 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) G01N 2333/43534 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011455 | Schoenecker et al. |
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FUNDED BY |
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APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
INVENTOR(S) | Jonathan Schoenecker (Nashville, Tennessee); Masato Yuasa (Nashville, Tennessee) |
ABSTRACT | A method for reducing or substantially preventing soft tissue calcification is provided. The method includes administering at least one of a downregulator of at least one plasmin inhibitors and plasmin(ogen) to a subject in need thereof, wherein the at least one plasmin inhibitor includes alpha2-antiplasmin. Further disclosed is a method comprises administering the compound subsequent to muscle injury, and the method further comprising administering an antifibrinolytic. |
FILED | Friday, March 17, 2017 |
APPL NO | 16/085973 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Original (OR) Class A61K 31/713 (20130101) A61K 38/005 (20130101) A61K 38/36 (20130101) A61K 45/06 (20130101) A61K 48/0016 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) A61P 43/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/341 (20130101) C12N 2310/346 (20130101) C12N 2310/3525 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011476 | Janssen-Heininger et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
ASSIGNEE(S) | The University of Vermont and State Agricultural College (Burlington, Vermont) |
INVENTOR(S) | Yvonne M. Janssen-Heininger (Charlotte, Vermont); Vikas Anathy (Essex Junction, Vermont) |
ABSTRACT | The present invention generally relates to systems and methods for treating certain oxidative stress conditions. In one aspect, compositions and methods of the invention can be used to treat a subject having an oxidative stress condition, for example, a subject having pulmonary fibrosis. In some embodiments, an inhibitor of ERp57 (for example, thiomuscimol) and/or an inhibitor of GSTP (for example, TLK-199) may be used to treat the subject. Also provided in certain aspects of the present invention are kits for such therapies, methods for promoting such therapies, and the like. |
FILED | Thursday, May 14, 2020 |
APPL NO | 15/931809 |
ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/197 (20130101) A61K 31/425 (20130101) A61K 31/425 (20130101) A61K 31/437 (20130101) A61K 31/437 (20130101) A61K 31/713 (20130101) A61K 38/06 (20130101) A61K 38/12 (20130101) Original (OR) Class A61K 38/45 (20130101) A61K 38/164 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1137 (20130101) C12N 2310/14 (20130101) Enzymes C12Y 205/01018 (20130101) C12Y 503/04001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011488 | Cherqui |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Stephanie Cherqui (La Jolla, California) |
ABSTRACT | Provided herein are methods for treating a disease or disorder associated with mitochondrial dysfunction through ex vivo introduction of a nucleic acid molecule into hematopoietic stem and progenitor cells (HSPCs) followed by transplantation of the HSPCs into a subject in need of treatment. The nucleic acid molecule may include a functional human frataxin (hFXN) or may include a gene editing system that when transfected into the cells removes a trinucleotide extension mutation of endogenous hFXN. |
FILED | Monday, March 16, 2020 |
APPL NO | 16/820368 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) A61K 35/28 (20130101) A61K 48/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/85 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011619 | Guha et al. |
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FUNDED BY |
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APPLICANT(S) | Montefiore Medical Center (Bronx, New York); Albert Einstein College of Medicine (Bronx, New York) |
ASSIGNEE(S) | MONTEFIORE MEDICAL CENTER (Bronx, New York); ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York) |
INVENTOR(S) | Chandan Guha (Scarsdale, New York); Stephen Barry (Haddonfield, New Jersey); Fernando Macian (Bronx, New York) |
ABSTRACT | Systems and methods for treating cancer and for preventing metastasis using low intensity focused ultrasound in combination with an anti-cancer therapy are disclosed. |
FILED | Wednesday, March 03, 2021 |
APPL NO | 17/191497 |
ART UNIT | 3797 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4836 (20130101) A61B 2090/374 (20160201) A61B 2090/378 (20160201) Preparations for Medical, Dental, or Toilet Purposes A61K 31/395 (20130101) A61K 41/0033 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) A61N 5/1077 (20130101) A61N 7/00 (20130101) Original (OR) Class A61N 2005/002 (20130101) A61N 2005/1061 (20130101) A61N 2005/1098 (20130101) A61N 2007/0004 (20130101) A61N 2007/0043 (20130101) A61N 2007/0065 (20130101) A61N 2007/0073 (20130101) A61N 2007/0078 (20130101) A61N 2007/0091 (20130101) A61N 2007/0095 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012329 | Tung et al. |
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FUNDED BY |
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APPLICANT(S) | Steve Tung (Fayetteville, Arkansas); Bo Ma (Fayetteville, Arkansas); Ty Seiwert (Fayetteville, Arkansas) |
ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
INVENTOR(S) | Steve Tung (Fayetteville, Arkansas); Bo Ma (Fayetteville, Arkansas); Ty Seiwert (Fayetteville, Arkansas) |
ABSTRACT | A method of fabricating a sensing device for DNA sequencing and biomolecule characterization including the steps of fabricating a microelectrode chip having a silicon substrate and a silicon nitride diaphragm, attaching a monolayer graphene sheet to the silicon nitride diaphragm, dicing a portion of the monolayer graphene sheet to form a graphene microribbon, converting the graphene microribbon to a graphene nanoribbon, and converting the graphene nanoribbon to a carbyne. A sensing device for DNA sequencing and biomolecule characterization is also disclosed. The sensing device includes a silicon substrate, a cavity in the silicon substrate covered by a silicon nitride layer, microelectrodes attached to the silicon nitride layer, graphene covering the microelectrodes, and carbyne attached to a portion of the silicon nitride layer covering said cavity. |
FILED | Thursday, February 11, 2021 |
APPL NO | 17/173839 |
ART UNIT | 2814 — Semiconductors/Memory |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/02 (20130101) B32B 7/12 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00071 (20130101) Original (OR) Class B81C 3/001 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012402 | Cuny et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas); TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas); TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
INVENTOR(S) | Gregory Cuny (Houston, Texas); Sameer Nikhar (Houston, Texas); Alexei Degterev (Brookline, Massachusetts) |
ABSTRACT | Identified compounds demonstrate protein kinase inhibitory activity. More specifically, the compounds are demonstrated to inhibit receptor interacting kinase 2 (RIPK2) and/or Activin-like kinase 2 (ALK2). Compounds that are either dual RIPK2/ALK2 inhibitors or that preferentially inhibit RIPK2 or ALK2 could provide therapeutic benefit. |
FILED | Wednesday, October 13, 2021 |
APPL NO | 17/499995 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012436 | Cherqui |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Stephanie Cherqui (La Jolla, California) |
ABSTRACT | Provided herein are methods for treating a disease or disorder associated with mitochondrial dysfunction through ex vivo introduction of a nucleic acid molecule into hematopoietic stem and progenitor cells (HSPCs) followed by transplantation of the HSPCs into a subject in need of treatment. The nucleic acid molecule may include a functional human frataxin (hFXN) or may include a gene editing system that when transfected into the cells removes a trinucleotide extension mutation of endogenous hFXN. |
FILED | Wednesday, March 15, 2017 |
APPL NO | 16/082487 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 67/0278 (20130101) A01K 2207/15 (20130101) A01K 2217/05 (20130101) A01K 2217/15 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/0318 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 2310/20 (20170501) C12N 2740/16043 (20130101) C12N 2800/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012437 | Cherqui |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Stephanie Cherqui (La Jolla, California) |
ABSTRACT | Provided herein are methods for treating a disease or disorder associated with mitochondrial dysfunction through ex vivo introduction of a nucleic acid molecule into hematopoietic stem and progenitor cells (HSPCs) followed by transplantation of the HSPCs into a subject in need of treatment. The nucleic acid molecule may include a functional human frataxin (hFXN) or may include a gene editing system that when transfected into the cells removes a trinucleotide extension mutation of endogenous hFXN. |
FILED | Friday, September 24, 2021 |
APPL NO | 17/484324 |
ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) A01K 67/0278 (20130101) A01K 2207/15 (20130101) A01K 2217/05 (20130101) A01K 2217/15 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/0318 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 14/47 (20130101) Original (OR) Class C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 2310/20 (20170501) C12N 2740/16043 (20130101) C12N 2800/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012438 | Schlom et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Jeffrey Schlom (Potomac, Maryland); Claudia M. Palena (Potomac, Maryland) |
ABSTRACT | The invention provides Brachyury deletion mutant polypeptides, nucleic acids encoding the polypeptides, non-yeast vectors comprising the nucleic acids, non-yeast cells, and methods of use. |
FILED | Monday, June 14, 2021 |
APPL NO | 17/346452 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 38/193 (20130101) A61K 38/1709 (20130101) A61K 39/0011 (20130101) A61K 39/00117 (20180801) A61K 39/001152 (20180801) A61K 39/001182 (20180801) A61K 45/06 (20130101) A61K 2039/70 (20130101) A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4702 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/10043 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012440 | Selsted et al. |
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FUNDED BY |
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APPLICANT(S) | THE UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
ASSIGNEE(S) | The University of Southern California (Davis, California) |
INVENTOR(S) | Michael E. Selsted (Pasadena, California); Dat Q. Tran (Alhambra, California); Justin B. Schaal (Orange, California); Virginia Basso (West Covina, California) |
ABSTRACT | Peptide analogs of a θ-defensin have been developed that provide a biphasic effect in treating disseminated fungal disease and/or associated septic shock. These analogs are active at concentrations below those needed to provide a fungicidal effect, and function by initially mobilizing effector cells of the immune system to address the infective organism followed by regulation of the immune system to down regulate the inflammatory response. These θ-defensin analogs are protective at concentrations where naturally occurring θ-defensins have no apparent effect, and include a core set of structural and sequence features not found in native θ-defensins. |
FILED | Friday, June 25, 2021 |
APPL NO | 17/358828 |
ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/4723 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012446 | Ogembo et al. |
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FUNDED BY |
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APPLICANT(S) | CITY OF HOPE (Duarte, California) |
ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
INVENTOR(S) | Javier Gordon Ogembo (San Dimas, California); Lorraine Zvichapera Mutsvunguma (Duarte, California) |
ABSTRACT | Disclosed herein are antibodies or immunogenic fragments thereof that specifically bind to Epstein-Barr virus (EBV) glycoprotein 350 (gp350) or 220 or one or more immunogenic peptides. Also disclosed are immunogenic peptides comprising fragments of gp350 amino acid sequence, EBV antibody-small molecule conjugates and pharmaceutical compositions comprising the antibody or an immunogenic fragment thereof, one or more immunogenic peptides, or the EBV antibody-small molecule conjugate. The antibodies, immunogenic peptides, conjugates, and pharmaceutical compositions can be used to treat or prevent EBV infections and EBV-associated conditions and diseases. |
FILED | Thursday, June 16, 2022 |
APPL NO | 17/807363 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/085 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/565 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012455 | Dimitrov et al. |
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FUNDED BY |
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APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Dimiter S. Dimitrov (Pittsburgh, Pennsylvania); Weizao Chen (Frederick, Maryland); Terry J. Fry (Aurora, Colorado); Christopher Chien (Falls Church, Virginia) |
ABSTRACT | Human monoclonal antibodies that specifically bind Fms-like tyrosine kinase 3 (FLT3) are described. Chimeric antigen receptors (CARs) and other antibody conjugates that include the FLT3-specific monoclonal antibodies are also described. Methods for the diagnosis and treatment of FLT3-associated cancer, such as acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML), are further described. |
FILED | Thursday, January 06, 2022 |
APPL NO | 17/570248 |
ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6849 (20170801) A61K 47/6929 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) A61P 35/04 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) C07K 16/468 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/577 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012463 | Ho et al. |
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FUNDED BY |
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APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Mitchell Ho (Urbana, Maryland); Nan Li (Laurel, Maryland); Bryan D. Fleming (Bethesda, Maryland) |
ABSTRACT | Monoclonal antibodies that bind glypican-2 (GPC2) with high affinity are described. Immunotoxins and chimeric antigen receptors (CARs) that include the disclosed antibodies or antigen-binding fragments thereof are further described. In some instances, the antibody or antigen-binding fragment is humanized. The disclosed GPC2-specific antibodies and conjugates can be used, for example, for the diagnosis or treatment of GPC2-positive cancers, including neuroblastoma, medulloblastoma and retinoblastoma. |
FILED | Tuesday, August 06, 2019 |
APPL NO | 17/266419 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6829 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 16/30 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5748 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012478 | Park et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Universita degli Studi di Trieste (Trieste, Italy) |
ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
INVENTOR(S) | Daewon Park (Englewood, Colorado); Brisa Pena Castellanos (Aurora, Colorado); Susanna Bosi (Trieste, Italy); Luisa Mestroni (Boulder, Colorado); Maurizio Prato (Trieste, Italy) |
ABSTRACT | Polymers suitable for forming carbon nanotube-functionalized reverse thermal gel compositions, compositions including the polymers, and methods of forming and using the polymers and compositions are disclosed. The compositions have reverse thermal gelling properties and transform from a liquid/solution to a gel—e.g., near or below body temperature. The polymers and compositions can be injected into or proximate an area in need of treatment. |
FILED | Tuesday, March 21, 2023 |
APPL NO | 18/124219 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/174 (20170801) C01B 2202/06 (20130101) C01B 2202/28 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/22 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/74 (20130101) Original (OR) Class C08G 18/3829 (20130101) C08G 83/001 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/005 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/041 (20170501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 2513/00 (20130101) C12N 2533/30 (20130101) C12N 2533/70 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012617 | Rohwer et al. |
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FUNDED BY |
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APPLICANT(S) | San Diego State University (SDSU) Foundation (San Diego, California) |
ASSIGNEE(S) | San Diego State University (SDSU) Foundation (San Diego, California) |
INVENTOR(S) | Forest Rohwer (San Diego, California); Jeremy J. Barr (San Diego, California) |
ABSTRACT | Provided are compositions and methods for treating, ameliorating and preventing infections, disorders and conditions in mammals, including genetically-predisposed and chronic disorders, where a microbial or bacterial flora is at least one causative or symptom-producing factor. Provided are compositions and methods used to treat, prevent or ameliorate an infection, for example, an infection in the gastrointestinal tract, or bowel. Provided are compositions and methods for treating, ameliorating and/or preventing a condition comprising an abnormal, disrupted or pathological mucosal surface or mucus-covered epithelium, or a condition caused, modified or effected by an abnormal, disrupted or pathological microbiotia, wherein optionally the infection or condition comprises a diarrhea, a colitis, obesity, diabetes, autism, a cystic fibrosis, a dysentery, a gastrointestinal infection, a gastrointestinal inflammation, a gastrointestinal dysbiosis, a gastrointestinal upset, a lung infection, a bacterial infection, a viral infection, a secondary infection, an inflammation, a mucus hypersecretion, or a dysbiosis. |
FILED | Tuesday, November 23, 2021 |
APPL NO | 17/534372 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 14/005 (20130101) C07K 2319/035 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2795/00021 (20130101) C12N 2795/00022 (20130101) C12N 2795/00031 (20130101) C12N 2795/00033 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012621 | Abudayyeh et al. |
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FUNDED BY |
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APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Omar Abudayyeh (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts) |
ABSTRACT | This disclosure provides systems, methods, and compositions for RNA-guided RNA-targeting CRISPR effectors for the treatment of diseases as well as diagnostics. In some embodiments, nucleotide deaminase functionalized CRISPR systems for RNA editing RNA knockdown, viral resistance, splicing modulation, RNA tracking, translation modulation, and epi-transcriptomic modifications are disclosed. |
FILED | Thursday, July 01, 2021 |
APPL NO | 17/365777 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/005 (20130101) Peptides C07K 2319/85 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/78 (20130101) C12N 15/11 (20130101) C12N 15/63 (20130101) C12N 15/102 (20130101) C12N 2310/20 (20170501) C12N 2320/10 (20130101) C12N 2320/33 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Enzymes C12Y 305/04004 (20130101) C12Y 305/04005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012633 | Ludwig et al. |
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FUNDED BY |
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APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Leif S. Ludwig (Cambridge, Massachusetts); Caleb A. Lareau (Boston, Massachusetts); Jacob C. Ulirsch (Boston, Massachusetts); Aviv Regev (Cambridge, Massachusetts); Vijay G. Sankaran (Boston, Massachusetts); Jason Buenrostro (Cambridge, Massachusetts); Christoph Muus (Cambridge, Massachusetts) |
ABSTRACT | Embodiments disclosed herein provide methods of using somatic mutations in mitochondrial genomes to retrospectively infer cell lineages in native contexts and to serve as genetic barcodes to measure clonal dynamics in complex cellular populations. Further, somatic mutations in mitochondrial DNA (mtDNA) are tracked by single cell genomic approaches for simultaneous analysis of single cell lineage and state. Applicants further show that mitochondrial mutations can be readily detected with contemporary single cell transcriptomic and epigenomic technologies to concomitantly capture gene expression profiles and chromatin accessibility, respectively. |
FILED | Tuesday, June 11, 2019 |
APPL NO | 17/251451 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6886 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012670 | Church et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | George M. Church (Brookline, Massachusetts); Francois Vigneault (Medford, Massachusetts); Uri Laserson (Boston, Massachusetts); Ido Bachelet (Brookline, Massachusetts) |
ABSTRACT | This disclosure provides methods for monitoring an immune response. Methods comprise linking a polynucleotide sequence encoding a heavy chain variable region and a polynucleotide sequence encoding a light chain variable region from a single lymphocyte from a biological sample obtained before an immune response and linking a polynucleotide sequence encoding a heavy chain variable region and a polynucleotide sequence encoding a light chain variable region from a single lymphocyte from a biological sample obtained during or after an immune response. Methods further comprise performing high-throughput sequencing of the linked (paired) sequences from before the immune response and from during or after the immune response, and comparing the resulting sequence reads. |
FILED | Wednesday, July 17, 2019 |
APPL NO | 16/513945 |
ART UNIT | 1675 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Peptides C07K 16/00 (20130101) C07K 16/065 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6874 (20130101) C12Q 1/6881 (20130101) C12Q 1/6881 (20130101) C12Q 1/6883 (20130101) C12Q 1/6883 (20130101) C12Q 2535/00 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 10/00 (20130101) Original (OR) Class C40B 30/04 (20130101) C40B 40/08 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 30/00 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013332 | Anderson et al. |
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FUNDED BY |
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APPLICANT(S) | Nicholas Anderson (Ijamsville, Maryland); Jeffery Debad (Ijamsville, Maryland); Eli N. Glezer (Chevy Chase, Maryland); Sudeep Kumar (Gaithersburg, Maryland); Noel Lawrence (Gaithersburg, Maryland); Kenneth Page (Germantown, Maryland); George Sigal (Rockville, Maryland); Sharon West (Rockville, Maryland) |
ASSIGNEE(S) | Meso Scale Technologies, LLC. (Rockville, Maryland) |
INVENTOR(S) | Nicholas Anderson (Ijamsville, Maryland); Jeffery Debad (Ijamsville, Maryland); Eli N. Glezer (Chevy Chase, Maryland); Sudeep Kumar (Gaithersburg, Maryland); Noel Lawrence (Gaithersburg, Maryland); Kenneth Page (Germantown, Maryland); George Sigal (Rockville, Maryland); Sharon West (Rockville, Maryland) |
ABSTRACT | Assay cartridges are described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain embodiments, these cartridges are adapted to receive and analyze a sample collected on an applicator stick. Also described are kits including such cartridges and a cartridge reader configured to analyze an assay conducted using an assay cartridge. |
FILED | Friday, March 30, 2012 |
APPL NO | 13/435885 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502723 (20130101) B01L 3/502746 (20130101) B01L 3/502784 (20130101) B01L 7/00 (20130101) B01L 9/527 (20130101) B01L 2200/04 (20130101) B01L 2200/12 (20130101) B01L 2200/16 (20130101) B01L 2200/025 (20130101) B01L 2200/141 (20130101) B01L 2200/147 (20130101) B01L 2200/0605 (20130101) B01L 2200/0684 (20130101) B01L 2200/0689 (20130101) B01L 2300/021 (20130101) B01L 2300/024 (20130101) B01L 2300/027 (20130101) B01L 2300/044 (20130101) B01L 2300/126 (20130101) B01L 2300/161 (20130101) B01L 2300/0645 (20130101) B01L 2300/0654 (20130101) B01L 2300/0809 (20130101) B01L 2300/0874 (20130101) B01L 2300/0877 (20130101) B01L 2300/0887 (20130101) B01L 2400/0487 (20130101) B01L 2400/0672 (20130101) B01L 2400/0683 (20130101) B01L 2400/0688 (20130101) Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/02 (20130101) G01F 23/292 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/10 (20130101) G01N 21/03 (20130101) G01N 21/05 (20130101) Original (OR) Class G01N 21/69 (20130101) G01N 21/76 (20130101) G01N 21/0303 (20130101) G01N 2021/054 (20130101) G01N 2021/0346 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0396 (20150401) Y10T 137/8593 (20150401) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013406 | Cabrera et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
INVENTOR(S) | Robert M. Cabrera (Houston, Texas); Richard H. Finnell (Austin, Texas) |
ABSTRACT | Provided are methods, compositions and kits to detect anti-folic acid antibodies in a sample, which are useful for identifying risk of pathologies associated with increased or decreased levels of anti-folic acid antibodies including infertility, folate responsive birth defects, folate responsive blood disorders, heart and vascular diseases, neurological disorders, neurodegenerative diseases and cancers. |
FILED | Monday, March 21, 2022 |
APPL NO | 17/699706 |
ART UNIT | 1678 — Printing/Measuring and Testing |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) Peptides C07K 16/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/82 (20130101) Original (OR) Class G01N 33/6854 (20130101) G01N 33/54366 (20130101) G01N 2800/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013572 | Vakoc et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Benjamin Vakoc (Arlington, Massachusetts); Meena Siddiqui (Boston, Massachusetts) |
ABSTRACT | Exemplary apparatus can be provided which can include a laser arrangement that is configured to provide a laser radiation, and including an optical cavity. The optical cavity can include a dispersive optical waveguide first arrangement having first and second sides, and which is configured to (i) receive at least one first electro-magnetic radiation at the first side so as to provide at least one second electro-magnetic radiation, and (ii) to receive at least one third electro-magnetic radiation at the second side so as to provide at least one fourth electro-magnetic radiation. The first and second sides are different from one another, and the second and third radiations are related to one another. The optical cavity can also include an active optical modulator second arrangement which can be configured to receive and modulate the fourth radiation so as to provide the first electro-magnetic radiation to the first arrangement. The laser radiation can be associated with at least one of the first, second, third or fourth radiations. |
FILED | Wednesday, March 30, 2022 |
APPL NO | 17/708143 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/6826 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02091 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/32 (20130101) Optical Elements, Systems, or Apparatus G02B 6/2932 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/106 (20130101) H01S 3/0675 (20130101) H01S 3/1062 (20130101) H01S 3/06791 (20130101) H01S 3/08086 (20130101) Coding; Decoding; Code Conversion in General H03M 1/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014488 | Madabhushi et al. |
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FUNDED BY |
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APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by the Department of Veteran Affairs (Washington, District of Columbia); UH Cleveland Medical Center (Cleveland, Ohio) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); UH Cleveland Medical Center (Cleveland, Ohio); The United States Government as Represente (Washington, District of Columbia) |
INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Neeraj Kumar (Cleveland Heights, Ohio); Joseph E. Willis (Shaker Heights, Ohio) |
ABSTRACT | Embodiments discussed herein facilitate determination of cancer stages based at least in part on shape, size, and/or texture features of cancer nuclei. One example embodiment is a method, comprising: accessing at least a portion of a digital whole slide image (WSI) comprising a tumor; segmenting (e.g., via a first deep learning model) the tumor on the at least the portion of the digital WSI; segmenting (e.g., via a second deep learning model) cancer nuclei in the segmented tumor; extracting one or more features from the segmented cancer nuclei; providing the one or more features extracted from the segmented cancer nuclei to a trained machine learning model; and receiving, from the machine learning model, an indication of a cancer stage of the tumor. |
FILED | Monday, January 04, 2021 |
APPL NO | 17/140586 |
ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/41 (20170101) G06T 7/62 (20170101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) G06T 2207/30028 (20130101) G06T 2207/30081 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 70/60 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014832 | Bihorac et al. |
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APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
INVENTOR(S) | Azra Bihorac (Gainesville, Florida); Xiaolin Li (Gainesville, Florida); Parisa Rashidi (Gainesville, Florida); Panagote Pardalos (Gainesville, Florida); Tezcan Ozrazgat-Baslanti (Gainesville, Florida); Wiliam Hogan (Gainesville, Florida); Daisy Zhe Wang (Gainesville, Florida); Petar Momcilovic (Gainesville, Florida); Gloria Lipori (Gainesville, Florida) |
ABSTRACT | Methods and systems disclosed herein utilize an automated analytics framework to implement a perioperative complication risk algorithm that uses existing clinical data in electronic health records to forecast patient-level probabilistic risk scores for eight major postoperative complications. An example method includes accessing health record data for a patient, normalizing the accessed health record data to generate a health record data set for the patient, transforming one or more features from the health record data set, selecting one or more transformed features from the health record data set, calculating risk probabilities for one or more complication risk categories based on the health record data set and the selected one or more features, calculating mortality risk probabilities for one or more mortality risk categories based on the calculated risk probabilities, and generating a personalized risk panel based on the calculated risk probabilities and the calculated mortality risk probabilities. |
FILED | Friday, June 01, 2018 |
APPL NO | 16/616534 |
ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/40 (20180101) G16H 50/30 (20180101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014835 | Meyer et al. |
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FUNDED BY |
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APPLICANT(S) | Vanderbilt University (Nashville, Tennessee); DUET Biosystems, Inc. (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee); Duet BioSystems Inc. (Nashville, Tennessee) |
INVENTOR(S) | Christian T. Meyer (Nashville, Tennessee); Vito Quaranta (Nashville, Tennessee); Leonard A. Harris (Nashville, Tennessee); Buddhi Bishal Paudel (Nashville, Tennessee); David J. Wooten (Nashville, Tennessee); Laurent Audoly (Brookline, Massachusetts) |
ABSTRACT | The invention provides methods for evaluating the therapeutic benefit of a combination therapy useful for treating a medical disorder, such as cancer. |
FILED | Friday, February 19, 2021 |
APPL NO | 17/180280 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/30 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 70/20 (20180101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 12011486 | Coleman et al. |
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FUNDED BY |
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APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
INVENTOR(S) | Matthew A. Coleman (Oakland, California); Nicholas O. Fischer (Livermore, California); Amy Rasley (Livermore, California); Craig D. Blanchette (San Leandro, California); Todd Peterson (Coronado, California) |
ABSTRACT | A telodendrimer-nanolipoprotein particle (t-NLP), comprising one or more membrane forming lipids, one or more telodendrimers, and a scaffold protein and a Chlamydia major outer membrane protein (MOMP) comprising a MOMP hydrophobic region, and related compositions methods and systems. |
FILED | Thursday, December 23, 2021 |
APPL NO | 17/561625 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0043 (20130101) A61K 9/1273 (20130101) A61K 9/1277 (20130101) A61K 39/39 (20130101) A61K 39/0208 (20130101) A61K 47/6915 (20170801) Original (OR) Class A61K 2039/54 (20130101) A61K 2039/543 (20130101) A61K 2039/545 (20130101) A61K 2039/6018 (20130101) A61K 2039/6093 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012429 | Sathitsuksanoh et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Noppadon Sathitsuksanoh (Louisville, Kentucky); Ning Sun (Fremont, California); Jian Shi (Albany, California); Anthe George (San Francisco, California); Manali Sawant (Cupertino, California); Seema Singh (Clarksburg, Maryland); Blake Simmons (San Francisco, California) |
ABSTRACT | The present invention provides novel and improved processes for treating a lignocellulosic biomass or technical lignin using ionic liquids to obtain lignin breakdown products and polysaccharide biomass components. Recycling of ionic liquids can be included in the methods of the invention. |
FILED | Tuesday, March 02, 2021 |
APPL NO | 17/189998 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Compounds of Unknown Constitution C07G 1/00 (20130101) Original (OR) Class Production of Cellulose by Removing Non-cellulose Substances From Cellulose-containing Materials; Regeneration of Pulping Liquors; Apparatus Therefor D21C 3/20 (20130101) D21C 11/0007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012434 | Johnson et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); University of Georgia Research Foundation, Inc. (Athens, Georgia) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); University of Georgia Research Foundation, Inc. (Athens, Georgia) |
INVENTOR(S) | Christopher W. Johnson (Denver, Colorado); Gregg Tyler Beckham (Golden, Colorado); Isabel Pardo Mendoza (Dos Hermanas, Spain); Ellen Lee Neidle (Dacula, Georgia) |
ABSTRACT | The present disclosure relates to a non-naturally occurring microorganism that includes a gene encoding a MucK transporter protein, where the microorganism is capable of catabolizing terephthalic acid (TPA). In some embodiments of the present disclosure, the gene encoding the MucK transporter protein may contain at least one mutation, relative to a reference gene encoding a reference MucK transporter protein. |
FILED | Monday, September 13, 2021 |
APPL NO | 17/472936 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 14/195 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012552 | Elliott et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Douglas C. Elliott (Richland, Washington); Gary G. Neuenschwander (Burbank, Washington); Todd R. Hart (Kennewick, Washington) |
ABSTRACT | A combined hydrothermal liquefaction (HTL) and catalytic hydrothermal gasification (CHG) system and process are described that convert various biomass-containing sources into separable bio-oils and aqueous effluents that contain residual organics. Bio-oils may be converted to useful bio-based fuels and other chemical feedstocks. Residual organics in HTL aqueous effluents may be gasified and converted into medium-BTU product gases and directly used for process heating or to provide energy. |
FILED | Wednesday, July 27, 2022 |
APPL NO | 17/875269 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Destructive Distillation of Carbonageous Materials for Production of Gas, Coke, Tar, or Similar Materials C10B 49/16 (20130101) Original (OR) Class Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 1/06 (20130101) C10G 1/065 (20130101) C10G 3/40 (20130101) C10G 3/50 (20130101) Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/00 (20130101) C10J 2200/06 (20130101) C10J 2300/0916 (20130101) C10J 2300/0973 (20130101) C10J 2300/1681 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 3/08 (20130101) C10L 9/08 (20130101) C10L 9/086 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/145 (20151101) Y02P 30/20 (20151101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012559 | Waldman et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Ruben Waldman (Chicago, Illinois); Hao-Cheng Yang (Westmont, Illinois); Seth B. Darling (Chicago, Illinois) |
ABSTRACT | A Janus membrane exhibiting sides with different properties and methods of fabricating such a Janus membrane. The membrane comprises a polymer material lacking polar functional groups. One side of the membrane is masked during atomic layer deposition (ALD). ALD is utilized to deposit a conformal coating on an exposed side of the membrane. |
FILED | Friday, May 11, 2018 |
APPL NO | 15/977831 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/168 (20170801) Treatment of Water, Waste Water, Sewage, or Sludge C02F 2101/325 (20130101) C02F 2305/08 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 33/06 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
12012603 — Yeast strains with selected or altered mitotypes and methods of making and using the same
US 12012603 | Hittinger et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Chris Todd Hittinger (Madison, Wisconsin); David Peris Navarro (Valencia, Spain); EmilyClare Patricia Baker (Madison, Wisconsin) |
ABSTRACT | Herein we demonstrate that the mitochondrial genome influences temperature tolerance in Saccharomyces yeasts. The present invention provides methods for manipulating the mitotype of yeast, including methods to produce synthetic yeast hybrids with a selected mitotype and methods to exchange the native mitochondrial DNA (mtDNA) present in polyploid yeast with mtDNA from a desired source. Saccharomyces cerevisiae×Saccharomyces eubayanus hybrids with selected mitotypes are also provided. The yeast and methods of the present invention may be utilized in a variety of applications, including in fermentation to produce beer and wine. |
FILED | Wednesday, August 07, 2019 |
APPL NO | 16/533928 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/18 (20130101) C12N 1/145 (20210501) C12N 15/81 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/645 (20210501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012642 | Lister et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (, None) |
INVENTOR(S) | Tedd E. Lister (Bangor, Maine); Luis A. Diaz Aldana (Idaho Falls, Idaho) |
ABSTRACT | A method of selectively recovering palladium from a palladium-containing material comprises providing a leaching solution comprising hydrochloric acid, hydrogen peroxide, and an iron salt comprising one or both of ferric chloride or ferrous chloride and contacting a palladium-containing material with the leaching solution to dissolve palladium from the palladium-containing material. Related methods of selectively recovering palladium from a palladium-containing material are also disclosed. |
FILED | Thursday, August 15, 2019 |
APPL NO | 16/541930 |
ART UNIT | 1738 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/10 (20130101) C22B 11/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012892 | Alahyari et al. |
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FUNDED BY |
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APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | RTX CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Abbas A. Alahyari (Glastonbury, Connecticut); Jon E. Sobanski (Glastonbury, Connecticut) |
ABSTRACT | A turbine engine is provided that includes a turbine engine core, a water separate and a core flowpath. The turbine engine core includes a core compressor section, a core combustor section and a core turbine section. The water separator includes a flowpath duct and a collector duct. The flowpath duct extends axially along and circumferentially about an axis. The collector duct extends axially along and circumferentially about the flowpath duct. The collector duct is fluidly coupled with the flowpath duct through a water permeable region in an outer wall of the flowpath duct. The core flowpath extends through the core compressor section, the core combustor section, the core turbine section and the flowpath duct from an inlet into the core flowpath to an exhaust from the core flowpath. The core flowpath extends axially along the water permeable region within the flowpath duct. |
FILED | Friday, May 19, 2023 |
APPL NO | 18/199767 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/052 (20130101) Original (OR) Class F02C 7/143 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/213 (20130101) F05D 2260/609 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013149 | Shrestha et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Som S. Shrestha (Oak Ridge, Tennessee); Kaushik Biswas (Davis, California); Diana Hun (Oak Ridge, Tennessee); Jerald A. Atchley (Oak Ridge, Tennessee) |
ABSTRACT | An improved system for thermal management is provided. The system includes thermally anisotropic composites coupled with a thermal loop to re-direct, reduce, and shape heat flows through a building envelope, having the potential to (1) significantly reduce envelope-generated heating and cooling loads and (2) provide grid services such as decreasing peak loads and shaping energy use. In one embodiment, the thermal management system includes an anisotropic composite that consists of alternating layers of thermal insulation and thermally conductive materials that are immediately adjacent to each other, including polyisocyanurate foam boards and aluminum sheets. The thermal management system also includes a thermal loop along the long edge or the entire the perimeter of the anisotropic composite, the thermal loop having dynamically controlled or floating temperature that is maintained at lower than an outdoor ambient temperature (for cooling). An interior wall structure is inwardly adjacent to the anisotropic composite. |
FILED | Wednesday, April 15, 2020 |
APPL NO | 16/849070 |
ART UNIT | 3633 — Static Structures, Supports and Furniture |
CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/62 (20130101) E04B 1/762 (20130101) Structural Elements; Building Materials E04C 2/525 (20130101) Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 5/0089 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013354 | Yao et al. |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regent of the University of California (Oakland, California) |
INVENTOR(S) | Norman Ying Yao (Berkeley, California); Raymond Jeanloz (Berkeley, California); Thomas Mittiga (Berkeley, California); Prabudhya Bhattacharyya (Berkeley, California); Thomas J. Smart (Berkeley, California); Francisco Machado (Berkeley, California); Bryce Kobrin (Berkeley, California); Soonwon Choi (Berkeley, California); Joel Moore (Berkeley, California); Satcher Hsieh (Berkeley, California); Chong Zu (Berkeley, California) |
ABSTRACT | A pressure chamber has a chamber wall. The chamber wall includes a sensor integrated within the chamber wall, wherein the sensor integrated in the chamber wall comprises defects. A method of determining an effect of pressure on a material is further described. The method includes applying pressure to a material within a pressure chamber and to a pressure chamber wall of the pressure chamber, where the pressure chamber wall has defects. A signal from the defects is sensed while the material and the pressure chamber wall are under pressure. A property of the material is determined based on the sensed signal. |
FILED | Thursday, December 19, 2019 |
APPL NO | 17/312893 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/28 (20170801) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/12 (20130101) G01N 23/20041 (20130101) Original (OR) Class G01N 2203/0488 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013788 | Brewer et al. |
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APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
INVENTOR(S) | Tony M. Brewer (Plano, Texas); Dean E. Walker (Allen, Texas) |
ABSTRACT | System and techniques for evicting a cache line with pending control request are described herein. A memory request—that includes an address corresponding to a set of cache lines—can be received. A determination can be made that a cache line of the set of cache lines will be evicted to process the memory request. Another determination can be made that a control request has been made to a host from the memory device and that the control request pending when it is determined that the cache line will be evicted. Here, a counter corresponding to the set of cache lines can be incremented (e.g., by one) to track the pending control request in face of eviction. Then, the cache line can be evicted. |
FILED | Tuesday, August 30, 2022 |
APPL NO | 17/823307 |
ART UNIT | 2132 — Memory Access and Control |
CURRENT CPC | Electric Digital Data Processing G06F 12/0891 (20130101) Original (OR) Class G06F 2212/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014277 | Suski et al. |
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APPLICANT(S) | Applied Engineering Concepts, Inc. (Eldersburg, Maryland) |
ASSIGNEE(S) | Applied Engineering Concepts, Inc. (Eldersburg, Maryland) |
INVENTOR(S) | William Charles Suski (Mount Pleasant, South Carolina); Christopher Alan Card (Eldersburg, Maryland); Brian Richard Few (Eldersburg, Maryland) |
ABSTRACT | A network authentication system can be configured for sampling a plurality of signal samples from a device on a network, providing the plurality of signal samples to a first machine-learned model that is configured to determine a device fingerprint based at least in part on the plurality of signal samples, and providing the device fingerprint to a second machine-learned model that is configured to classify the device based at least in part on the device fingerprint. |
FILED | Wednesday, April 19, 2023 |
APPL NO | 18/303119 |
ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Electric Digital Data Processing G06F 18/214 (20230101) G06F 18/2411 (20230101) G06F 18/24765 (20230101) Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) G06N 3/084 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 10/764 (20220101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014484 | Winters et al. |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Caroline Winters (Cedar Crest, New Mexico); Kathryn N. Gabet Hoffmeister (Albuquerque, New Mexico); Elizabeth M. C. Jones (Cedar Crest, New Mexico); Amanda Jones (Cedar Crest, New Mexico); Jacob Thomas Mahaffey (Albuquerque, New Mexico); Shannon Elizabeth Murray (Albuquerque, New Mexico); Michael M. Montoya (Bernalillo, New Mexico); Wendy Flores-Brito (Pittsburgh, Pennsylvania) |
ABSTRACT | The invention advances the ratio method of phosphor thermography using two machine vision cameras for full-field temperature measurements of a solid surface. As an example, algorithms from digital image correlation (DIC) can be used to determine the stereoscopic imaging system intrinsic and extrinsic parameters, and accurately register material points on the sample to subpixel locations in each image with 0.07 px or better accuracy. A phosphor calibration sample fabricated using aerosol deposition can be used for in situ determination of the temperature-versus-intensity ratio relationship. The full calibration methodology and several improvements on two-color phosphor thermography open the door for full-field temperature measurements in dynamic tests with deforming test specimens. In particular, thermographic phosphors can be combined with stereo digital image correlation in a novel diagnostic, TP+DIC, to measure time-resolved full-field surface strains and temperatures simultaneously, thereby enabling testing in combined thermo-mechanical environments. |
FILED | Monday, June 13, 2022 |
APPL NO | 17/838777 |
ART UNIT | 2896 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0004 (20130101) Original (OR) Class G06T 7/85 (20170101) G06T 7/292 (20170101) G06T 2207/10048 (20130101) G06T 2207/30108 (20130101) Pictorial Communication, e.g Television H04N 13/239 (20180501) H04N 23/56 (20230101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014838 | Rotsch et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | David A. Rotsch (Montgomery, Illinois); Nicholas A. Smith (Lockport, Illinois); David A. Ehst (Downers Grove, Illinois); Sergey A. Chemerisov (Lisle, Illinois); Jerry A. Nolen, Jr. (Chicago, Illinois); Michael Alexander Brown (Chicago, Illinois); James J. Grudzinski (Downers Grove, Illinois); James L. Bailey (Hinsdale, Illinois); Ronald T. Kmak (Homer Glen, Illinois) |
ABSTRACT | A system for producing and harvesting radioisotopes is provided, the system having a converter housing defining a first beam window; a converter carrier and cartridge in slidable communication with the converter housing; a target housing positioned downstream from the converter housing, the target housing defining a second beam window; and a target carrier in slidable communication with the target housing. |
FILED | Monday, August 27, 2018 |
APPL NO | 16/113817 |
ART UNIT | 3619 — Printing/Measuring and Testing |
CURRENT CPC | Conversion of Chemical Elements; Radioactive Sources G21G 1/10 (20130101) G21G 1/12 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 5/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014853 | Wang et al. |
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APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Jinming Liu (Minneapolis, Minnesota); Bin Ma (Roseville, Minnesota); Fan Zhang (Minneapolis, Minnesota); Guannan Guo (Minneapolis, Minnesota); Yiming Wu (Shoreview, Minnesota); Xiaowei Zhang (Minneapolis, Minnesota) |
ABSTRACT | In general, the disclosure is directed to bulk iron-nitride materials having a polycrystalline microstructure having pores including a plurality of crystallographic grains surrounded by grain boundaries, where at least one crystallographic grain includes an iron-nitride phase including any of a body centered cubic (bcc) structure, a body centered tetragonal (bct), and a martensite structure. The disclosure further describes techniques producing a bulk iron-nitride material having a polycrystalline microstructure, including: melting an iron source to obtain a molten iron source; fast belt casting the molten iron source to obtain a cast iron source; cooling and shaping the cast iron source to obtain a bulk iron-containing material having a body-centered cubic (bcc) structure; annealing the bulk iron-containing material at an austenite transformation temperature and subsequently cooling the bulk iron-containing material; and nitriding the bulk iron-containing material to obtain the bulk iron-nitride material. |
FILED | Tuesday, May 28, 2019 |
APPL NO | 17/058882 |
ART UNIT | 1759 — Printing/Measuring and Testing |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/0622 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/60 (20130101) C01P 2002/72 (20130101) C01P 2002/77 (20130101) C01P 2004/02 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2006/42 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/02 (20130101) C23C 8/26 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/047 (20130101) Original (OR) Class H01F 41/0253 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015036 | Hall et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Regents of the University of California (Oakland, California) |
INVENTOR(S) | David Lawrence Hall (San Ramon, California); Mihail Bora (Livermore, California); Adam Conway (Livermore, California); Philip Datte (Concord, California); Qinghui Shao (Fremont, California); Erik Lars Swanberg, Jr. (Livermore, California); Clement Antoine Trosseille (San Ramon, California); Charles Edward Hunt (Davis, California) |
ABSTRACT | Devices, systems and methods for solid-state X-ray detection with high temporal resolution are described. An example method includes receiving an X-ray pulse in a semiconductor chip resulting in an electron cloud being formed in the semiconductor chip, applying a first set of voltages across a first plurality of drift cathode strips on a first side of the semiconductor chip and a second plurality of drift cathode strips on a second side of the semiconductor chip, applying a second set of voltages to across the first and the second plurality of drift cathode strips to form an electric field having a linear profile to cause the electron cloud to drift along the middle of the semiconductor chip, and activating a counter cathode on the second side and one or more readout anodes on the first side to collect the electron cloud after spreading in the middle section of the semiconductor chip. |
FILED | Tuesday, April 27, 2021 |
APPL NO | 17/241594 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/083 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 22/12 (20130101) H01L 27/14603 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015149 | Archer et al. |
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FUNDED BY |
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APPLICANT(S) | Cornell University (Ithaca, New York) |
ASSIGNEE(S) | Cornell University (Ithaca, New York) |
INVENTOR(S) | Lynden A. Archer (Ithaca, New York); Qing Zhao (Tianjin, China PRC) |
ABSTRACT | Provided are passivation layers for batteries. The batteries may be aqueous aluminum batteries. The passivation layer may be disposed on a portion of or all of a surface or surfaces of an anode, which may be an aluminum or aluminum alloy anode. The passivation layer is bonded to the surface of the anode. The passivation layer may be an organic, nitrogen-rich material and inorganic Al-halide rich or Al-nitrate rich material. The passivation layer may be formed by contacting an aluminum or aluminum alloy substrate, which may be aluminum or aluminum alloy anode, with one or more aluminum halide and one or more ionic liquid. |
FILED | Monday, August 12, 2019 |
APPL NO | 17/267465 |
ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/48 (20130101) H01M 4/366 (20130101) H01M 4/0426 (20130101) H01M 4/463 (20130101) Original (OR) Class H01M 4/5815 (20130101) H01M 50/44 (20210101) H01M 50/417 (20210101) H01M 50/437 (20210101) H01M 50/491 (20210101) H01M 50/497 (20210101) H01M 2300/0008 (20130101) H01M 2300/0011 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015156 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Lu Zhang (Lisle, Illinois); Zhangxing Shi (Westmont, Illinois); Andrew Jansen (Bolingbrook, Illinois); Stephen Trask (Batavia, Illinois) |
ABSTRACT | An silicon-containing electrode is formed by coating a silicon-containing slurry onto a conductive current collector. The slurry comprises a binder solution comprising a poly(carboxylic acid) binder dissolved in a mixed solvent system comprising an amide solvent of Formula I, as described herein, and a second solvent which can be water and/or an organic solvent. The binder preferably comprises poly(acrylic acid). The mixed solvent system comprises about 10 to about 99 vol % of the amide solvent of Formula I. The binder solution is utilized as a solvent for a slurry of silicon-containing particles for preparing the silicon-containing electrode. The slurries comprising the mixed solvent system have higher viscosity and are more stable than slurries containing the same concentrations of silicon particles, carbon particles, and binder in water as the sole solvent. |
FILED | Tuesday, November 15, 2022 |
APPL NO | 17/987605 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/02 (20130101) C08K 3/04 (20130101) C08K 2003/023 (20130101) C08K 2201/005 (20130101) C08K 2201/011 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) C09D 7/20 (20180101) C09D 7/67 (20180101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/22 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/386 (20130101) H01M 4/0404 (20130101) H01M 4/0471 (20130101) H01M 4/622 (20130101) Original (OR) Class H01M 4/1395 (20130101) H01M 10/0525 (20130101) H01M 2004/027 (20130101) H01M 2220/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015378 | Escarra et al. |
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FUNDED BY |
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APPLICANT(S) | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana) |
ASSIGNEE(S) | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana) |
INVENTOR(S) | Matthew David Escarra (New Orleans, Louisiana); Luke Artzt (New Orleans, Louisiana); Yaping Ji (New Orleans, Louisiana); Daniel Codd (New Orleans, Louisiana); Matthew Barrios (New Orleans, Louisiana); Kazi M. Islam (New Orleans, Louisiana); David M. Bar-On (New Orleans, Louisiana); Jacqueline C. Failla (New Orleans, Louisiana); Claire C. Davis (New Orleans, Louisiana); Maxwell W. Woody (New Orleans, Louisiana) |
ABSTRACT | A hybrid receiver for a concentrator photovoltaic-thermal power system combines a concentrator photovoltaic (CPV) module and a thermal module that converts concentrated sunlight into electrical energy and thermal heat. Heat transfer fluid flowing through a cooling block removes waste heat generated by photovoltaic cells in the CPV module. The heat transfer fluid then flows through a helical tube illuminated by sunlight that misses the CPV module. Only one fluid system is used to both remove the photovoltaic-cell waste heat and capture high-temperature thermal energy from sunlight. Fluid leaving the hybrid receiver can have a temperature greater than 200° C., and therefore may be used as a source of process heat for a variety of commercial and industrial applications. The hybrid receiver can maintain the photovoltaic cells at temperatures below 110° C. while achieving overall energy conversion efficiencies exceeding 80%. |
FILED | Sunday, June 14, 2020 |
APPL NO | 17/619185 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 10/744 (20180501) F24S 20/20 (20180501) F24S 23/72 (20180501) F24S 30/452 (20180501) F24S 70/65 (20180501) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/06 (20130101) H01L 31/0336 (20130101) H01L 31/0512 (20130101) H01L 31/03046 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/44 (20141201) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12016118 | Zinn et al. |
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FUNDED BY |
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APPLICANT(S) | KUPRION INC. (San Jose, California) |
ASSIGNEE(S) | Kuprion Inc. (Waterbury, Connecticut) |
INVENTOR(S) | Alfred A. Zinn (Palo Alto, California); Khanh Nguyen (San Jose, California) |
ABSTRACT | Printed circuit boards may be formed using ceramic substrates with high thermal conductivity to facilitate heat dissipation. Metal nanoparticles, such as copper nanoparticles, may be used to form conductive traces and fill through-plane vias upon the ceramic substrates. Multi-layer printed circuit boards may comprise two or more ceramic substrates adhered together, wherein each ceramic substrate has one or more conductive traces defined thereon and the one or more conductive traces are formed through consolidation of metal nanoparticles. The one or more conductive traces in a first ceramic substrate layer are in electrical communication with at least one second ceramic substrate layer adjacent thereto. |
FILED | Friday, February 26, 2021 |
APPL NO | 17/760079 |
ART UNIT | 2847 — Electrical Circuits and Systems |
CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/092 (20130101) H05K 1/115 (20130101) H05K 1/181 (20130101) H05K 1/183 (20130101) H05K 1/0306 (20130101) Original (OR) Class H05K 3/46 (20130101) H05K 3/107 (20130101) H05K 3/303 (20130101) H05K 3/4038 (20130101) H05K 2201/09227 (20130101) H05K 2201/09563 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 12011868 | Baer et al. |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
INVENTOR(S) | Eric Baer (Cleveland Heights, Ohio); Andrew Olah (Spencer, Ohio); Cong Zhang (Shaker Heights, Ohio); Gary Wnek (Cleveland, Ohio); Nathan McMullen (Cleveland, Ohio); Chung-Fu Cheng (Aurora, Ohio) |
ABSTRACT | A method of producing high modulus and strength polymer materials includes compressive rolling a semicrystalline polymer material in at least two different axial directions of the material; and axially orienting at least a portion of the compressive rolled material to a draw ratio less than the ultimate elongation or the elongation % at break of the material. |
FILED | Wednesday, September 14, 2022 |
APPL NO | 17/944403 |
ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/003 (20130101) B29C 45/0001 (20130101) B29C 48/07 (20190201) B29C 48/0011 (20190201) B29C 48/022 (20190201) B29C 59/04 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/08 (20130101) B29K 2023/12 (20130101) B29K 2023/16 (20130101) B29K 2023/065 (20130101) B29K 2995/0051 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/731 (20130101) B29L 2031/768 (20130101) B29L 2031/4821 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 7/02 (20130101) C08K 2201/004 (20130101) C08K 2201/011 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012118 | Faller |
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APPLICANT(S) | Perceptive Automata Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Perceptive Automata, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Avery Wagner Faller (Boston, Massachusetts) |
ABSTRACT | A vehicle collects video data of an environment surrounding the vehicle including traffic entities, e.g., pedestrians, bicyclists, or other vehicles. The captured video data is sampled and the sampled video frames are presented to users to provide input on a traffic entity's state of mind. The system determines an attribute value that describes a statistical distribution of user responses for the traffic entity. If the attribute for a sampled video frame is within a threshold of the attribute of another video frame, the system interpolates attribute for a third video frame between the two sampled video frames. Otherwise, the system requests further user input for a video frame captured between the two sampled video frames. The interpolated and/or user based attributes are used to train a machine learning based model that predicts a hidden context of the traffic entity. The trained model is used for navigation of autonomous vehicles. |
FILED | Tuesday, October 27, 2020 |
APPL NO | 17/081202 |
ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 30/0956 (20130101) B60W 60/001 (20200201) Original (OR) Class B60W 2420/403 (20130101) Electric Digital Data Processing G06F 18/214 (20230101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image or Video Recognition or Understanding G06V 10/774 (20220101) G06V 10/7788 (20220101) G06V 20/46 (20220101) G06V 20/48 (20220101) G06V 20/58 (20220101) G06V 40/20 (20220101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012492 | Wiesner et al. |
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APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York); YALE UNIVERSITY (New Haven, Connecticut) |
ASSIGNEE(S) | Cornell University (Ithaca, New York); Yale University (New Haven, Connecticut) |
INVENTOR(S) | Ulrich B. Wiesner (Ithaca, New York); Rachel M. Dorin (San Francisco, California); Joerg Werner (San Francisco, California); William A. Phillip (New Haven, Connecticut) |
ABSTRACT | A method for forming an isoporous graded film comprising multiblock copolymers and isoporous graded films. The films have a surface layer and a bulk layer. The surface layer can have at least 1×1014 pores/m2 and a pore size distribution (dmax/dmin)) of less than 3. The bulk layer has an asymmetric structure. The films can be used in filtration applications. |
FILED | Monday, August 29, 2022 |
APPL NO | 17/897751 |
ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 67/0009 (20130101) B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 71/022 (20130101) B01D 71/26 (20130101) B01D 71/28 (20130101) B01D 71/44 (20130101) B01D 71/80 (20130101) B01D 2325/04 (20130101) B01D 2325/021 (20130101) B01D 2325/023 (20130101) B01D 2325/48 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 297/04 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) Original (OR) Class C08J 2353/00 (20130101) Compositions of Macromolecular Compounds C08L 53/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
12012603 — Yeast strains with selected or altered mitotypes and methods of making and using the same
US 12012603 | Hittinger et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Chris Todd Hittinger (Madison, Wisconsin); David Peris Navarro (Valencia, Spain); EmilyClare Patricia Baker (Madison, Wisconsin) |
ABSTRACT | Herein we demonstrate that the mitochondrial genome influences temperature tolerance in Saccharomyces yeasts. The present invention provides methods for manipulating the mitotype of yeast, including methods to produce synthetic yeast hybrids with a selected mitotype and methods to exchange the native mitochondrial DNA (mtDNA) present in polyploid yeast with mtDNA from a desired source. Saccharomyces cerevisiae×Saccharomyces eubayanus hybrids with selected mitotypes are also provided. The yeast and methods of the present invention may be utilized in a variety of applications, including in fermentation to produce beer and wine. |
FILED | Wednesday, August 07, 2019 |
APPL NO | 16/533928 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/18 (20130101) C12N 1/145 (20210501) C12N 15/81 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/645 (20210501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012662 | Ozkan et al. |
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FUNDED BY |
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APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
INVENTOR(S) | Umit Ozkan (Columbus, Ohio); Seval Gunduz (Columbus, Ohio); Dhruba Jyoti Deka (Columbus, Ohio) |
ABSTRACT | Disclosed herein are doped perovskite oxides. The doped perovskite oxides may be used as a cathode material in an electrochemical cell to electrochemically generate ammonia from N2. The doped perovskite oxides may be combined with nitride compounds, for instance iron nitride, to further increase the efficiency of the ammonia production. |
FILED | Wednesday, April 26, 2023 |
APPL NO | 18/307289 |
ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 49/009 (20130101) C01G 51/70 (20130101) C01G 53/70 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) C01P 2002/50 (20130101) C01P 2006/40 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/2633 (20130101) C04B 35/2641 (20130101) C04B 35/58042 (20130101) C04B 2235/3274 (20130101) C04B 2235/3852 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 1/27 (20210101) C25B 9/19 (20210101) C25B 9/23 (20210101) C25B 11/047 (20210101) C25B 11/051 (20210101) C25B 11/069 (20210101) Original (OR) Class C25B 11/0773 (20210101) C25B 13/04 (20130101) C25B 13/07 (20210101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012981 | Aksak et al. |
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APPLICANT(S) | TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas) |
ASSIGNEE(S) | TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas) |
INVENTOR(S) | Burak Aksak (Lubbock, Texas); Luciano Castillo (Carmel, Indiana); Humberto Bocanegra Evans (Lubbock, Texas) |
ABSTRACT | A coating apparatus for the reduction of aerodynamic noise and vibrations. The coating apparatus is configured to include a group of fibrillar structures, wherein each fibrillar structure is configured with a diverging tip so that the coating reduces the size of and shifts downstream, a separation bubble, and modulates large-scale recirculating motion. Each fibrillar structure can be configured as a cylindrical micropillar. The group of fibrillar structures can be configured as a group of uniformly distributed cylindrical micropillars (e.g., one or more micropillar arrays). The surface coating is effective in reducing the separation bubble and displacing the separation bubble downstream. The coating facilitates a reduction in noise (e.g., aerodynamic noise) and vibrations due to the reduction in the size of the separation bubble. |
FILED | Friday, October 09, 2020 |
APPL NO | 17/067464 |
ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Aeroplanes; Helicopters B64C 21/10 (20130101) B64C 2230/26 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/0035 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013292 | Chakrabartty et al. |
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APPLICANT(S) | Washington University (St. Louis, Missouri) |
ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Shantanu Chakrabartty (St. Louis, Missouri); Liang Zhou (St. Louis, Missouri) |
ABSTRACT | A sensor system for detecting events includes an array of memory devices and a read-out interface. Each memory device includes a floating-gate with a sensing interface, the sensing interface having an energy barrier configured to leak electrons at a predetermined electron leakage rate through Fowler-Nordheim (F-N) tunneling. An an input to the sensing interface is configured to alter a geometry of the energy barrier to change the electron leakage rate. The read-out interface is communicatively coupled to at least one memory device, and is configured to retrieve data stored on the at least one memory device for analysis. |
FILED | Thursday, May 20, 2021 |
APPL NO | 17/325863 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/06 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 3/04 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013354 | Yao et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regent of the University of California (Oakland, California) |
INVENTOR(S) | Norman Ying Yao (Berkeley, California); Raymond Jeanloz (Berkeley, California); Thomas Mittiga (Berkeley, California); Prabudhya Bhattacharyya (Berkeley, California); Thomas J. Smart (Berkeley, California); Francisco Machado (Berkeley, California); Bryce Kobrin (Berkeley, California); Soonwon Choi (Berkeley, California); Joel Moore (Berkeley, California); Satcher Hsieh (Berkeley, California); Chong Zu (Berkeley, California) |
ABSTRACT | A pressure chamber has a chamber wall. The chamber wall includes a sensor integrated within the chamber wall, wherein the sensor integrated in the chamber wall comprises defects. A method of determining an effect of pressure on a material is further described. The method includes applying pressure to a material within a pressure chamber and to a pressure chamber wall of the pressure chamber, where the pressure chamber wall has defects. A signal from the defects is sensed while the material and the pressure chamber wall are under pressure. A property of the material is determined based on the sensed signal. |
FILED | Thursday, December 19, 2019 |
APPL NO | 17/312893 |
ART UNIT | 2852 — Printing/Measuring and Testing |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/28 (20170801) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/12 (20130101) G01N 23/20041 (20130101) Original (OR) Class G01N 2203/0488 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013449 | Chen et al. |
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APPLICANT(S) | University of Houston System (Houston, Texas) |
ASSIGNEE(S) | University of Houston System (Houston, Texas) |
INVENTOR(S) | Ji Chen (Sugar Land, Texas); Jianfeng Zheng (Sugar Land, Texas) |
ABSTRACT | In an embodiment, the present disclosure pertains to electric field generators that include a signal generator electrically connected to a power amplifier, a impedance matching circuit electrically connected to the power amplifier, and a power divider electrically connected to the impedance matching circuit and to at least one of a first wall, a second wall, a third wall, a fourth wall, or a base area. In an additional embodiment, the present disclosure pertains to method of determining radio frequency (RF)-induced heating on a medical device utilizing an electric field generator of the present disclosure. Additional embodiments of the present disclosure pertain to methods of making electric field generators for testing a medical device. |
FILED | Monday, December 13, 2021 |
APPL NO | 17/549503 |
ART UNIT | 2853 — Printing/Measuring and Testing |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 25/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/288 (20130101) Original (OR) Class Amplifiers H03F 1/565 (20130101) H03F 3/20 (20130101) H03F 2200/387 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013986 | Sinha et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Ayan Sinha (West Lafayette, Indiana); Chiho Choi (West Lafayette, Indiana); Joon Hee Choi (West Lafayette, Indiana); Karthik Ramani (West Lafayette, Indiana) |
ABSTRACT | A method for hand pose identification in an automated system includes providing map data of a hand of a user to a first neural network trained to classify features corresponding to a joint angle of a wrist in the hand to generate a first plurality of activation features and performing a first search in a predetermined plurality of activation features stored in a database in the memory to identify a first plurality of hand pose parameters for the wrist associated with predetermined activation features in the database that are nearest neighbors to the first plurality of activation features. The method further includes generating a hand pose model corresponding to the hand of the user based on the first plurality of hand pose parameters and performing an operation in the automated system in response to input from the user based on the hand pose model. |
FILED | Monday, June 13, 2022 |
APPL NO | 17/838887 |
ART UNIT | 2624 — Selective Visual Display Systems |
CURRENT CPC | Electric Digital Data Processing G06F 3/017 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image or Video Recognition or Understanding G06V 10/454 (20220101) G06V 20/653 (20220101) G06V 30/194 (20220101) G06V 40/11 (20220101) G06V 40/113 (20220101) Pictorial Communication, e.g Television H04N 13/271 (20180501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014246 | Bhaskar et al. |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Mihir Keshav Bhaskar (Cambridge, Massachusetts); Denis D. Sukachev (Cambridge, Massachusetts); Christian Thieu Nguyen (Cambridge, Massachusetts); Bartholomeus Machielse (Cambridge, Massachusetts); David S. Levonian (Cambridge, Massachusetts); Ralf Riedinger (Cambridge, Massachusetts); Mikhail D. Lukin (Cambridge, Massachusetts); Marko Loncar (Cambridge, Massachusetts) |
ABSTRACT | Systems and methods are disclosed for making a quantum network node. A plurality of scoring function F values are calculated for an array of at least two photonic crystal cavity unit cells, each having a lattice constant a and a hole having a length Hx and a width Hy. A value of a, a value of Hx, and a value of Hy are selected for which a scoring function value is at a maximum. A waveguide region and the array of at least two photonic crystal cavity unit cells based on the selected values are formed on a substrate. At least one ion between a first photonic crystal cavity unit cell and a second photonic crystal cavity unit cell are implanted and annealed into a quantum defect. A coplanar microwave waveguide is formed on the substrate in proximity to the array of at least two photonic crystal cavity unit cells. |
FILED | Thursday, July 16, 2020 |
APPL NO | 17/623757 |
ART UNIT | 2634 — Digital Communications |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Optical Elements, Systems, or Apparatus G02B 6/1225 (20130101) Computer Systems Based on Specific Computational Models G06N 10/70 (20220101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014488 | Madabhushi et al. |
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APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by the Department of Veteran Affairs (Washington, District of Columbia); UH Cleveland Medical Center (Cleveland, Ohio) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); UH Cleveland Medical Center (Cleveland, Ohio); The United States Government as Represente (Washington, District of Columbia) |
INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Neeraj Kumar (Cleveland Heights, Ohio); Joseph E. Willis (Shaker Heights, Ohio) |
ABSTRACT | Embodiments discussed herein facilitate determination of cancer stages based at least in part on shape, size, and/or texture features of cancer nuclei. One example embodiment is a method, comprising: accessing at least a portion of a digital whole slide image (WSI) comprising a tumor; segmenting (e.g., via a first deep learning model) the tumor on the at least the portion of the digital WSI; segmenting (e.g., via a second deep learning model) cancer nuclei in the segmented tumor; extracting one or more features from the segmented cancer nuclei; providing the one or more features extracted from the segmented cancer nuclei to a trained machine learning model; and receiving, from the machine learning model, an indication of a cancer stage of the tumor. |
FILED | Monday, January 04, 2021 |
APPL NO | 17/140586 |
ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/41 (20170101) G06T 7/62 (20170101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) G06T 2207/30028 (20130101) G06T 2207/30081 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 70/60 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014835 | Meyer et al. |
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FUNDED BY |
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APPLICANT(S) | Vanderbilt University (Nashville, Tennessee); DUET Biosystems, Inc. (Nashville, Tennessee) |
ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee); Duet BioSystems Inc. (Nashville, Tennessee) |
INVENTOR(S) | Christian T. Meyer (Nashville, Tennessee); Vito Quaranta (Nashville, Tennessee); Leonard A. Harris (Nashville, Tennessee); Buddhi Bishal Paudel (Nashville, Tennessee); David J. Wooten (Nashville, Tennessee); Laurent Audoly (Brookline, Massachusetts) |
ABSTRACT | The invention provides methods for evaluating the therapeutic benefit of a combination therapy useful for treating a medical disorder, such as cancer. |
FILED | Friday, February 19, 2021 |
APPL NO | 17/180280 |
ART UNIT | 2857 — Printing/Measuring and Testing |
CURRENT CPC | Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/30 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 70/20 (20180101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
12015092 — Physical forms of MXene materials exhibiting novel electrical and optical characteristics
US 12015092 | Ghidiu et al. |
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FUNDED BY |
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APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Michael J Ghidiu (Bridgeton, New Jersey); Michel W Barsoum (Moorestown, New Jersey); Yury Gogotsi (Warminster, Pennsylvania); Aaron Thomas Fafarman (Philadelphia, Pennsylvania); Andrew DeVries Dillon (Philadelphia, Pennsylvania) |
ABSTRACT | The present invention(s) is directed to novel conductive Mn+1Xn(Ts) compositions exhibiting high volumetric capacitances, and methods of making the same. The present invention(s) is also directed to novel conductive Mn+1Xn(Ts) compositions, methods of preparing transparent conductors using these materials, and products derived from these methods. |
FILED | Wednesday, February 23, 2022 |
APPL NO | 17/678120 |
ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/914 (20170801) C01B 32/921 (20170801) C01B 32/949 (20170801) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/56 (20130101) C04B 35/58 (20130101) C04B 35/5607 (20130101) C04B 35/5618 (20130101) C04B 35/58007 (20130101) C04B 2235/445 (20130101) C04B 2235/3201 (20130101) C04B 2235/3203 (20130101) C04B 2235/3205 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/022466 (20130101) Original (OR) Class H01L 33/42 (20130101) Organic electric solid-state devices H10K 50/805 (20230201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015195 | Eid et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Aline Eid (Atlanta, Georgia); Jimmy Georges Donald Hester (Atlanta, Georgia); Emmanouil Manos Tentzeris (Atlanta, Georgia) |
ABSTRACT | The disclosed technology includes device, systems, techniques, and methods for mm-wave energy harvesting utilizing a Rotman-Lens-based rectenna system. An energy harvester system can include one or more antenna, a Rotman Lens having a beam port side and an antenna side in electrical communication with the one or more antenna, and a rectifier network in electrical communication with the beam port side of the Rotman Lens. The energy harvester system can also include a power combining network in electrical communication with the rectifier network and having an output. The rectifier network can include a plurality of rectifiers connected to the beam port side of the Rotman Lens. Further, each of the plurality of rectifiers can include a rectifying diode. The power combining network can include a plurality of bypass diodes. |
FILED | Thursday, April 30, 2020 |
APPL NO | 17/607435 |
ART UNIT | 2849 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/248 (20130101) Original (OR) Class H01Q 21/065 (20130101) H01Q 25/008 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/001 (20200101) H02J 50/27 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015862 | Ma et al. |
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FUNDED BY |
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APPLICANT(S) | Gigajot Technology, Inc. (Pasadena, California) |
ASSIGNEE(S) | Gigajot Technology, Inc. (Pasadena, California) |
INVENTOR(S) | Jiaju Ma (Monrovia, California); Saleh Masoodian (Monrovia, California) |
ABSTRACT | According to some embodiments, an image sensor pixel includes a floating diffusion, a transistor gate configured to transfer charge with respect to the floating diffusion, and a doped pinning region disposed between the floating diffusion and the transistor gate, to reduce or eliminate the effective capacitive coupling between the floating diffusion and the transistor gate. The transistor gate may be an in-pixel transfer gate configured to selectively transfer photocharge from an in-pixel charge accumulation region to the floating diffusion. Alternatively, or additionally, the transistor gate may be an in-pixel reset gate configured to selectively reset the electrostatic potential of the floating diffusion. |
FILED | Friday, May 24, 2019 |
APPL NO | 17/058506 |
ART UNIT | 2894 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14612 (20130101) Pictorial Communication, e.g Television H04N 25/59 (20230101) H04N 25/65 (20230101) H04N 25/75 (20230101) Original (OR) Class H04N 25/616 (20230101) H04N 25/778 (20230101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 12011405 | Rovekamp et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Administrator of the NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | Roger Rovekamp (Kemah, Texas); Christopher Beck (Houston, Texas); Craig Cornwall (Boise, Idaho) |
ABSTRACT | A system and method is provided for a wearable robotic upper body garment. In an embodiment, an upper body garment or apparatus comprises a shoulder saddle, one or more actuators, one or more flexible tendons, back torso section, front, torso section, torso wrap, and upper arm cuff. The shoulder saddle may be comprised of a yoke and one or more elevated shoulder sections. The one or more elevated shoulder sections may be comprised of a first elevated shoulder section. In an embodiment, the back torso and front torso sections may be structurally connected to the yoke. In an embodiment, the one or more actuators may be structurally connected to either said back torso section or front torso section. In an embodiment, the one or more flexible tendons may be operationally connected to a predetermined one or more actuators and an upper arm cuff. In an embodiment and during operations, the one or more actuators effectuate a pulling motion on one or more flexible tendons enabling or augmenting movement about an upper extremity joint. |
FILED | Thursday, May 13, 2021 |
APPL NO | 17/319198 |
ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/002 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0281 (20130101) Original (OR) Class A61H 2201/165 (20130101) A61H 2201/1614 (20130101) A61H 2201/1635 (20130101) A61H 2201/1671 (20130101) A61H 2205/062 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011857 | Jenett et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); United States Government as Represented by The Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
INVENTOR(S) | Benjamin Jenett (Cambridge, Massachusetts); Neil Gershenfeld (Cambridge, Massachusetts); Kenneth Cheung (Emerald Hills, California); Christine Gregg (Emerald Hills, California) |
ABSTRACT | A method for the design, manufacture, and assembly of modular lattice structures composed of cuboctahedron unit cells. |
FILED | Monday, November 14, 2022 |
APPL NO | 18/055136 |
ART UNIT | 1748 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0001 (20130101) B29C 45/0005 (20130101) B29C 45/006 (20130101) Original (OR) Class B29C 45/0017 (20130101) B29C 45/26 (20130101) B29C 65/02 (20130101) B29C 65/48 (20130101) B29C 65/60 (20130101) B29C 66/7254 (20130101) B29C 2045/0022 (20130101) B29C 2045/0067 (20130101) B29C 2045/2683 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/04 (20130101) B29K 2307/04 (20130101) B29K 2309/08 (20130101) B29K 2995/0094 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012236 | Warden et al. |
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FUNDED BY |
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APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
INVENTOR(S) | Harry Kendall Warden (Huntsville, Alabama); Jeffrey Wayne Weathers (Huntsville, Alabama); James Boyd Weathers (Huntsville, Alabama) |
ABSTRACT | A collet assembly, for an umbilical plate that connects a vehicle to a ground station prior to a launch of the vehicle, includes an active decoupler. The active decoupler includes a pin. A cuff has a central opening. The pin passes through the central opening. A plurality of fingers are pivotally coupled to the cuff. A plurality of levers are pivotally coupled to the plurality of fingers and the pin. |
FILED | Friday, January 07, 2022 |
APPL NO | 17/647351 |
ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 5/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012647 | Smith et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States Government Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | Timothy M. Smith (Cleveland, Ohio); Robert W. Carter (Cleveland, Ohio); Christopher A. Kantzos (Cleveland, Ohio); Michael J. Kulis (Cleveland, Ohio) |
ABSTRACT | An additive manufacturing powdered composite material includes metal particles coated with a coating of ceramic particles. The metal particles may include a ternary NiCoCr alloy, with select additions of minor amounts of other elements. The ceramic particles may include yttrium oxide or other oxides. The composite material is suitable for additive manufacturing (AM) into a component for high temperature (>1000° C.) applications. The AM component includes a metal matrix formed from the alloy, with the ceramic particles dispersed in the matrix. |
FILED | Friday, June 19, 2020 |
APPL NO | 16/906319 |
ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/05 (20220101) B22F 1/07 (20220101) B22F 1/16 (20220101) B22F 2302/25 (20130101) B22F 2304/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/10 (20200101) B33Y 80/00 (20141201) Alloys C22C 30/00 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/12014 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013277 | Ramsey |
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FUNDED BY |
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APPLICANT(S) | RAPA Technologies, LLC (Meriden, New Hampshire) |
ASSIGNEE(S) | RAPA Technologies, LLC (Meriden, New Hampshire) |
INVENTOR(S) | Marc C. Ramsey (Meriden, New Hampshire) |
ABSTRACT | Systems and methods for storing fluid are described. In some embodiments, a system may include a container having an internal volume that is configured to change as fluid enters or exits, a first shell component, and a second shell component. The first shell component may limit an expansion of the container in a first direction, and the second shell component may limit the expansion of the container in a second direction that is opposite the first direction. |
FILED | Tuesday, January 17, 2023 |
APPL NO | 18/155262 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/241 (20130101) Original (OR) Class G01F 23/248 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12015472 | Velazco |
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FUNDED BY |
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APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
INVENTOR(S) | Jose E. Velazco (Altadena, California) |
ABSTRACT | Interplanetary networks for space internet and space positioning are presented. The described networks deploy spacecraft swarms along the solar system to form a science and communications platform. The disclosed network nodes are placed around planetary Lagrange points. Creation of optical synthetic apertures using smallsat swarms for inter- and intranet communications is further described. Exemplary subnetworks such as the cislunar network are also presented. |
FILED | Wednesday, March 16, 2022 |
APPL NO | 17/696679 |
ART UNIT | 2644 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/2676 (20130101) Transmission H04B 7/18521 (20130101) Original (OR) Class H04B 7/18528 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 12010952 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
ASSIGNEE(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
INVENTOR(S) | Xiao Zhang (Richland, Washington); Changki Mo (Richland, Washington); Matthew David Whiting (Prosser, Washington); Qin Zhang (Richland, Washington) |
ABSTRACT | Compositions and methods of protecting plants from cold damage are provided. In particular, the invention provides compositions comprising plant-based nano- and/or micron-sized particles which, when applied to plants or plant parts such as buds, form a non-hydrophilic deposit or film with low thermal conductivity, thereby conferring protection against damage from ice nucleation and cold stress. |
FILED | Monday, June 28, 2021 |
APPL NO | 17/359727 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 13/065 (20130101) Original (OR) Class Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 105/14 (20130101) C09D 197/02 (20130101) C09D 197/005 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12010994 | Gurtler |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); MANTROSE HAEUSER CO., INC. (Lincoln, Rhode Island) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Joshua Gurtler (Phoenixville, Pennsylvania) |
ABSTRACT | Compositions and methods for reducing microbial loads on agricultural products are disclosed. The compositions include at least one acidulant and at least one surfactant, each present in an effective amount to reduce a microbial load on an agricultural product. The methods include applying compositions of at least one acidulant and at least one surfactant to agricultural products to reduce microbial loads and cross contamination of agricultural processing equipment. |
FILED | Wednesday, September 11, 2019 |
APPL NO | 16/567487 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/30 (20130101) A01N 37/36 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12011845 | Zhu et al. |
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FUNDED BY |
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APPLICANT(S) | The United States, as represented by the Secretary of Agriculture (Washington, District of Columbia); Jiaqi Dai (Washington, District of Columbia); Yelizaveta Pikus (Phoenix, Arizona) |
ASSIGNEE(S) | |
INVENTOR(S) | Junyong Zhu (Madison, Wisconsin); Roland Gleisner (Jefferson, Wisconsin); Riley Simson (Madison, Wisconsin); Jiaqi Dai (Washington, District of Columbia); Yelizaveta Pikus (Phoenix, Arizona) |
ABSTRACT | Methods for producing structural materials from lumber are provided. The methods use an oxygen pre-treatment or a carbonate pre-treatment followed by densification via thermal compression to produce structural materials with strong mechanical properties. The pre-treatments are able to partially delignify the lumber without substantially adversely affecting the mechanical properties of the subsequently densified wood. |
FILED | Thursday, July 14, 2022 |
APPL NO | 17/864763 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Processes, Apparatus or Selection of Substances for Impregnating, Staining, Dyeing, Bleaching of Wood or Similar Materials, or Treating of Wood or Similar Materials With Permeant Liquids, Not Otherwise Provided for; Chemical or Physical Treatment of Cork, Cane, Reed, Straw or Similar Materials B27K 3/08 (20130101) B27K 3/18 (20130101) B27K 3/32 (20130101) B27K 5/065 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12012369 | Huang et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
INVENTOR(S) | Kun Huang (Conshohocken, Pennsylvania); Richard D. Ashby (Glenside, Pennsylvania); Xuetong Fan (North Wales, Pennsylvania); Helen N. Lew (Wynnewood, Pennsylvania); Robert A. Moreau (Quakertown, Pennsylvania) |
ABSTRACT | Compositions containing at least one compound of formula I where R1 is a phenolic compound (e.g., simple phenol, creosote, thymol, or carvacrol), and where R2 is a polyamine (e.g., ethylenediamine (EDA), diethylenetriamine (DETA), triethylenetetramine (TETA), tetraethylenepentamine (TEPA), hexamethylenediamine (HDA)); and optionally a carrier; the compositions may additionally contain at least one epoxy resin. Methods for killing microorganisms involving contacting the microorganisms with an effective microorganism killing amount of the above composition. Compositions containing at least one compound produced by a method involving reacting phenolic-branched chain fatty acid methyl ester with at least one polyamine. |
FILED | Friday, August 21, 2020 |
APPL NO | 16/999142 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/50 (20130101) Acyclic or Carbocyclic Compounds C07C 231/02 (20130101) Original (OR) Class C07C 237/10 (20130101) Heterocyclic Compounds C07D 233/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
12012603 — Yeast strains with selected or altered mitotypes and methods of making and using the same
US 12012603 | Hittinger et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Chris Todd Hittinger (Madison, Wisconsin); David Peris Navarro (Valencia, Spain); EmilyClare Patricia Baker (Madison, Wisconsin) |
ABSTRACT | Herein we demonstrate that the mitochondrial genome influences temperature tolerance in Saccharomyces yeasts. The present invention provides methods for manipulating the mitotype of yeast, including methods to produce synthetic yeast hybrids with a selected mitotype and methods to exchange the native mitochondrial DNA (mtDNA) present in polyploid yeast with mtDNA from a desired source. Saccharomyces cerevisiae×Saccharomyces eubayanus hybrids with selected mitotypes are also provided. The yeast and methods of the present invention may be utilized in a variety of applications, including in fermentation to produce beer and wine. |
FILED | Wednesday, August 07, 2019 |
APPL NO | 16/533928 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/18 (20130101) C12N 1/145 (20210501) C12N 15/81 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/645 (20210501) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 12011282 | Najafi et al. |
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FUNDED BY |
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APPLICANT(S) | Baylor College of Medicine (Houston, Texas); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia); Arizona Broad of Regents on behalf of Arizona State University (Tucson, Arizona) |
ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas); Arizona Board of Regents on behalf of Arizona State University (Tuscon, Arizona); The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Bijan Najafi (Houston, Texas); Javad Razjouyan (Houston, Texas); He Zhou (Houston, Texas); Mark Kunik (Bellaire, Texas) |
ABSTRACT | An instrumented trail-making task (iTMT) platform includes a wearable sensor and interactive interface technology configured to identify cognitive-cognitive impairment in individuals such as older adults. The iTMT platform may be programmed with neuropsychological tests for assessing individuals. The iTMT may provide information on visual search, scanning, speed of processing, mental flexibility, and/or executive functions as well as physical biomarkers of motor performance including slowness, weakness, exclusion, and/or motor planning error. Results of tests administered by the iTMT system may be reported to a patient or caregiver and used in identifying cogni-tive-motor impairment among individuals suffering from cognitive impairment, dementia, and/or those with frailty status, and/or cognitive frailty, and/or high risk of falling, and/or high likelihood of decline in cognitive-motor over time. |
FILED | Monday, September 18, 2017 |
APPL NO | 16/334571 |
ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1124 (20130101) A61B 5/4088 (20130101) Original (OR) Class A61B 5/6829 (20130101) A61B 2562/0219 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014488 | Madabhushi et al. |
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FUNDED BY |
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APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by the Department of Veteran Affairs (Washington, District of Columbia); UH Cleveland Medical Center (Cleveland, Ohio) |
ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio); UH Cleveland Medical Center (Cleveland, Ohio); The United States Government as Represente (Washington, District of Columbia) |
INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Neeraj Kumar (Cleveland Heights, Ohio); Joseph E. Willis (Shaker Heights, Ohio) |
ABSTRACT | Embodiments discussed herein facilitate determination of cancer stages based at least in part on shape, size, and/or texture features of cancer nuclei. One example embodiment is a method, comprising: accessing at least a portion of a digital whole slide image (WSI) comprising a tumor; segmenting (e.g., via a first deep learning model) the tumor on the at least the portion of the digital WSI; segmenting (e.g., via a second deep learning model) cancer nuclei in the segmented tumor; extracting one or more features from the segmented cancer nuclei; providing the one or more features extracted from the segmented cancer nuclei to a trained machine learning model; and receiving, from the machine learning model, an indication of a cancer stage of the tumor. |
FILED | Monday, January 04, 2021 |
APPL NO | 17/140586 |
ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/41 (20170101) G06T 7/62 (20170101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) G06T 2207/30028 (20130101) G06T 2207/30081 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 70/60 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
US 12013568 | Cheung et al. |
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FUNDED BY |
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APPLICANT(S) | HEWLETT PACKARD ENTERPRISE DEVELOPMENT LP (Houston, Texas) |
ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
INVENTOR(S) | Stanley Cheung (Milpitas, California); Yuan Yuan (Milpitas, California); Di Liang (Santa Barbara, California); Raymond G. Beausoleil (Milpitas, California) |
ABSTRACT | Implementations disclosed herein provide for improving phase tuning efficiency of optical devices, such as a hybrid metal-on-semiconductor capacitor (MOSCAP) III-V/Si micro-ring laser. The present disclosure integrates silicon devices into a waveguide structural of the optical devices disclosed herein, for example, a waveguide resistor heater, a waveguide PIN diode, and waveguide PN diode. In some examples, the optical devices is a MOSCAP formed by a dielectric layer between two semiconductor layers, which provides for small phase tuning via plasma dispersion and/or carrier dispersion effect will occur depending on bias polarity. The plasma dispersion and/or carrier dispersion effect is enhanced according to implementations disclosed herein by heat, carrier injection, and/or additional plasma dispersion based on the silicon devices disclosed integrated into the waveguide. |
FILED | Tuesday, March 15, 2022 |
APPL NO | 17/695673 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/12004 (20130101) Original (OR) Class G02B 2006/12061 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/025 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/026 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12013573 | Peng et al. |
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FUNDED BY |
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APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
INVENTOR(S) | Yiwei Peng (Milpitas, California); Yuan Yuan (Milpitas, California); Zhihong Huang (Milpitas, California) |
ABSTRACT | Examples described herein relate to an optical resonating device. The optical resonating device includes a primary waveguide, a microring resonator, and a microring resonator photodiode. The primary waveguide allows a passage of an optical signal. The microring resonator is formed adjacent to the primary waveguide to couple therein a portion of the optical signal passing through the primary waveguide. Furthermore, the microring resonator photodiode is formed adjacent to the microring resonator to measure an intensity of the portion of the optical signal coupled into the microring resonator. |
FILED | Thursday, July 14, 2022 |
APPL NO | 17/812554 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) G02B 6/1225 (20130101) G02B 6/12004 (20130101) G02B 6/29338 (20130101) Original (OR) Class G02B 6/29343 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/015 (20130101) G02F 2201/58 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 12014315 | Briggman et al. |
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FUNDED BY |
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APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
INVENTOR(S) | Chandra A. Briggman (Springfield, Virginia); Jane Elizabeth Quenk (Washington, District of Columbia); Timothy M. Moran (National Harbor, Maryland); Kelley A. Sullivan (Alexandria, Virginia); Robert E. Dixon, Jr. (Washington, District of Columbia) |
ABSTRACT | A method, electronic device, and computer-readable storage medium. A request is received to display a calendar identifying incoming physical item deliveries regarding a user's delivery point. User-associated shipment information is accessed identifying at least one first item scheduled for physical delivery and at least one second item scheduled for electronic delivery, and includes a record of physical delivery items and electronic delivery items. A sender's address is automatically populated to a recipient's address book, when a notification is received regarding the physical delivery item being in transit. Tracking data associated with the at least one first item from an integrated mail database and an integrated mail processing equipment is acquired and includes at least an expected delivery date. A notification regarding the at least one first item is displayed within a portion of an interface representative of the expected delivery date on the calendar. |
FILED | Tuesday, January 10, 2023 |
APPL NO | 18/152559 |
ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) G06Q 10/083 (20130101) G06Q 10/0833 (20130101) Original (OR) Class G06Q 10/1093 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 51/42 (20220501) H04L 51/214 (20220501) H04L 51/234 (20220501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12014513 | Simpson |
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FUNDED BY |
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APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Ryan J. Simpson (Vienna, Virginia) |
ABSTRACT | The present disclosure relates to a system and method for automatically determining a three dimensional size of an item. The system may include an optical sensor scanning a surface of the item being transported on a conveyor spaced apart from the optical sensor by a conveyor distance, the surface including a standard size element having a first dimension. The system may also include a memory storing the first dimension and the conveyor distance. The system may also include a processor configured to calculate a second dimension of the surface based on a scanned image of the surface and a scanned image of the standard size element and the stored first dimension. The processor may obtain an item distance between the optical sensor and the surface and determine a height of the item based on the obtained item distance and the stored conveyor distance. |
FILED | Friday, February 26, 2021 |
APPL NO | 17/186512 |
ART UNIT | 2672 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/026 (20130101) G01B 11/043 (20130101) G01B 11/046 (20130101) Image Data Processing or Generation, in General G06T 7/62 (20170101) Original (OR) Class G06T 7/70 (20170101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 12014247 | Seif Tabrizi et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); Government of the United States of America, as Represented by the Secretary of Commerce (Gaithersburg, Maryland) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); Government of the United States of America, As Represented by the Secretary of Commerce (Gaithersburg, Maryland) |
INVENTOR(S) | Seyed Alireza Seif Tabrizi (Adelphi, Maryland); Mohammad Hafezi (Washington, District of Columbia); Yi-Kai Liu (Gaithersburg, Maryland) |
ABSTRACT | A method for detecting a two-qubit correlated dephasing error includes accessing a signal of a quantum system, where the quantum system includes a plurality of qubits. Every qubit has a nonzero rate of dephasing and some qubits have a nonzero rate of correlated dephasing. The signal further includes information about a matrix that includes diagonal elements and off-diagonal elements. The off-diagonal elements of the matrix are 2s-sparse. The method further includes performing randomized measurements of the off-diagonal elements of the matrix and recovering the matrix based on a direct measurement of the diagonal elements of the matrix. |
FILED | Friday, May 13, 2022 |
APPL NO | 17/743850 |
ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/70 (20220101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 12016107 | Dobie et al. |
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FUNDED BY |
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APPLICANT(S) | Texas Research International, Inc (Austin, Texas) |
ASSIGNEE(S) | TEXAS RESEARCH INTERNATIONAL, INC. (Austin, Texas); US GOVERNMENT AS REPRESENTED BY THE SECRETARY OF THE ARMY (Natick, Massachusetts) |
INVENTOR(S) | Michael Jay Dobie (Double Oak, Texas); Anthony Patti (Wakefield, Massachusetts); Robert Philip Brushaber (Austin, Texas); Frank Thomas Zeller (Dripping Springs, Texas); Neal S. Cooper (N. Richland Hills, Texas) |
ABSTRACT | A continuous mode conveyor cooking appliance utilizing hot air jet impingement and microwave energy for cooking prepared foods. The approach envisions a central microwave unit with a hot air jet impingement oven unit on each side of the microwave section and a conveyor system to carry the food items completely through the appliance from one end to the other and with the two hot air jet impingement ovens equipped with a designed combination of hot air jet impingement jets and solid pins to act as a microwave attenuation system to reduce microwave exposure to cooking personnel to completely safe levels. |
FILED | Friday, March 19, 2021 |
APPL NO | 17/207532 |
ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
CURRENT CPC | Bakers\' Ovens; Machines or Equipment for Baking A21B 1/245 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 5/15 (20160801) Kitchen Equipment; Coffee Mills; Spice Mills; Apparatus for Making Beverages A47J 37/045 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/76 (20130101) H05B 6/647 (20130101) Original (OR) Class H05B 6/707 (20130101) H05B 6/763 (20130101) H05B 6/782 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 12012866 | Bondarevsky et al. |
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FUNDED BY |
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APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
ASSIGNEE(S) | RTX Corporation (Farmington, Connecticut) |
INVENTOR(S) | Dana K. Bondarevsky (Sturbridge, Massachusetts); Christopher Corcoran (Planstville, Connecticut); Bryan P. Dube (Chepachet, Rhode Island); Yuta Yoshimura (Meriden, Connecticut); David D. Chapdelaine (Ellington, Connecticut); Christopher Paul Perron (Tolland, Connecticut) |
ABSTRACT | An airfoil for a gas turbine engine is configured to extend in a radial direction relative to an engine axis from an inner diameter to an outer diameter. The airfoil comprises a body having a base disposed at the inner diameter, a tip disposed at the outer diameter, a leading edge, a trailing edge, and pressure and suction side walls extending between the leading edge and the trailing edge and between the base and the tip. The body defines an interior cavity. A first wall is disposed in the interior cavity, extends radially, and adjoins the pressure side wall and the suction side wall to form a first cooling channel. A first hole through the first wall connects the first cooling channel to a second cooling channel. The first hole has a profile that tapers inward toward the base. |
FILED | Monday, June 12, 2023 |
APPL NO | 18/208684 |
ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/18 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
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This week's information is published in the FedInvent Patents report for Tuesday, June 18, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
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APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
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The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240618.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page