FedInvent™ Patents
Patent Details for Tuesday, June 25, 2024
This page was updated on Wednesday, June 26, 2024 at 05:11 PM GMT
Department of Health and Human Services (HHS)
| US 12016628 | Yao et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Xincheng Yao (Hinsdale, Illinois); Tae Yun Son (Chicago, Illinois) |
| ABSTRACT | A multi-modal functional OCT imaging methodology and system are provided that enable concurrent intrinsic optical signal (IOS) imaging of stimulus-evoked neural activity and hemodynamic responses at capillary resolution. An OCT angiography (OCTA)-guided IOS analysis is used to separate neural-IOS and hemodynamic-IOS changes in the same retinal image sequence. The OCTA-guided IOS data processing used for this purpose differentiates two functional images, namely, a neural-IOS map and a hemodynamic-IOS map, from the same image dataset. |
| FILED | Tuesday, March 27, 2018 |
| APPL NO | 16/497071 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0008 (20130101) A61B 3/0025 (20130101) A61B 3/102 (20130101) Original (OR) Class A61B 3/1241 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/45 (20130101) G01J 3/0208 (20130101) G01J 2003/451 (20130101) Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 2207/10101 (20130101) G06T 2207/30041 (20130101) G06T 2211/404 (20130101) G06T 2219/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016634 | He et al. |
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| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Bin He (Pittsburgh, Pennsylvania); Rui Sun (Pittsburgh, Pennsylvania); Abbas Sohrabpour (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein are methods and apparatus for the imaging of brain electrical activity from electromagnetic measurements, using deep learning neural networks where a simulation process is designed to model realistic brain activation and electromagnetic signals to train generalizable neural networks and a residual convolutional neural network and/or a recurrent neural network is trained using the simulated data, capable of estimating source distributions from electromagnetic measurements, and their temporal dynamics over time, for pathological signals in diseased brains, such as interictal activity and ictal signals, and physiological brain signals such as evoked brain responses and spontaneous brain activity. |
| FILED | Monday, May 10, 2021 |
| APPL NO | 17/315691 |
| ART UNIT | 3798 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/245 (20210101) A61B 5/369 (20210101) A61B 34/10 (20160201) Original (OR) Class A61B 2034/105 (20160201) Electric Digital Data Processing G06F 30/23 (20200101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016657 | Xia et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| INVENTOR(S) | Jun Xia (Amherst, New York); Yuehang Wang (Buffalo, New York) |
| ABSTRACT | Devices and methods for photoacoustic tomography are disclosed herein. One exemplary photoacoustic tomography device uses a laser to produce acoustic waves in a sample. A transducer receives the acoustic waves through a slit formed by one or more blades positioned substantially parallel to the receiving aperture of the transducer. An acoustic absorber is affixed to each of the one or more blades along a surface proximal to the transducer. A processor acquires acoustic data and reconstructs photoacoustic tomographic images based on the acquired data. Reconstructing the image involves setting reconstruction parameters, defining a reconstruction area, reconstruction position, and pixel size, and calculating an acoustic travelling path for the sample to each transducer element. The acoustic travelling paths are saved into a three-dimensional array. |
| FILED | Tuesday, March 08, 2022 |
| APPL NO | 17/689123 |
| ART UNIT | 3798 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0073 (20130101) A61B 5/0095 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/1702 (20130101) G01N 29/24 (20130101) G01N 29/2418 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 23/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016682 | Ferguson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University Of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Brian Scott Ferguson (Goleta, California); Hyongsok Tom Soh (Santa Barbara, California); David A. Hoggarth (Toronto, Canada) |
| ABSTRACT | The present disclosure provides devices, methods and systems for analyte detection and/or monitoring, e.g., the continuous and/or semi-continuous monitoring of in-vivo analyte concentrations in real time. Generally, the devices, methods and systems of the present disclosure make use of signaling probes; methods or devices for reducing interferent-based fouling of the signaling probes, non-specific binding to the signaling probes and/or occlusion of a sensor surface; and methods and/or devices for providing an adjusted signal based on a detected signal from the signaling probes. Compositions including conformation switching signaling probes are also provided. |
| FILED | Wednesday, January 29, 2014 |
| APPL NO | 14/768134 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1473 (20130101) A61B 5/4839 (20130101) A61B 5/14525 (20130101) Original (OR) Class A61B 5/14546 (20130101) A61B 5/14735 (20130101) A61B 5/150992 (20130101) A61B 2503/40 (20130101) A61B 2503/42 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2320/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 2525/205 (20130101) C12Q 2565/629 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016687 | Vlasov et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Yurii Vlasov (Urbana, Illinois); Yan Zhang (Urbana, Illinois); Christopher Kenji Brenden (Urbana, Illinois); Prasoon Kumar Jha (Urbana, Illinois); Yifei Yan (Urbana, Illinois); Sungho Kim (Urbana, Illinois) |
| ABSTRACT | Provided are implantable probes for analyzing biological fluids and related methods of using and making. The probe is formed with an integrated on-chip probe body that provides for collection and storage of analyte from biological fluid and facilitates subsequent analysis, including by a mass spectrometer (MS). The analysis has high spatial accuracy as the probe tip that collects biological fluid sample is small, including less than 100 μm with an opening less than 10 μm. Temporal information can be obtained by storing the analyte from the biological fluid as a train of droplets separated by an immiscible fluid. The probe body can be electrically energized to facilitate sample ionization and transfer to a MS analysis device. In this manner, the integrated on-chip probe body facilitates analyte collection, storage and subsequent analysis within a single probe body material, including a doped silicon material. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/356062 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/14503 (20130101) A61B 5/14507 (20130101) A61B 5/14546 (20130101) Original (OR) Class A61B 10/0045 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016688 | Weinberger |
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| FUNDED BY |
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| APPLICANT(S) | GenNext Technologies, Inc. (Half Moon Bay, California) |
| ASSIGNEE(S) | GENNEXT TECHNOLOGIES, INC. (Half Moon Bay, California) |
| INVENTOR(S) | Scot Randy Weinberger (Montara, California) |
| ABSTRACT | Systems and methods of in vivo hydroxyl radical protein foot-printing are presented. These teachings may be used to, for example, study three-dimensional protein structure or bio-kinetics. Radical Dosimetry including an optional intrinsic standard is used on isolated intact cells. Real-time feedback based on an internal standard provides comparability between different experiments and in vivo analysis results in data that is representative of actual biological conditions. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 17/411855 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1455 (20130101) Original (OR) Class A61B 5/14546 (20130101) A61B 2562/0233 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/53 (20130101) G01N 21/631 (20130101) G01N 21/645 (20130101) G01N 33/6803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016701 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yong Wang (St. Louis, Missouri); Gloria Guzman (St. Louis, Missouri); Qing Wang (St. Louis, Missouri); Tammie Benzinger (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Yong Wang (St. Louis, Missouri); Gloria Guzman (St. Louis, Missouri); Qing Wang (St. Louis, Missouri); Tammie Benzinger (St. Louis, Missouri) |
| ABSTRACT | Provided herein are methods for imaging and diagnosing at least one disorder in a patient utilizing diffusion basis spectrum imaging MRI with extended isotropic spectrum (DBSI-EIS). The methods may be used as a tool to image and diagnose heterogeneities within tumors. As a result, different tumor types can be detected, distinguished from one another, and individually quantified without the need to inject exogenous contrast agents. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 16/329608 |
| ART UNIT | 3798 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/004 (20130101) A61B 5/055 (20130101) A61B 5/743 (20130101) A61B 5/4887 (20130101) Original (OR) Class A61B 5/7264 (20130101) A61B 5/7271 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5602 (20130101) G01R 33/56341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016740 | Gerber et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Matthew Gerber (Los Angeles, California); Yu-Hsiu Lee (Los Angeles, California); Tsu-Chin Tsao (Los Angeles, California); Jacob Rosen (Los Angeles, California); Jean-Pierre Hubschman (Los Angeles, California) |
| ABSTRACT | A docking system for intraocular surgery that is configured to simultaneously: (1) physically stabilize a position and an orientation of an eye during intraocular surgical procedures; (2) preserve an unobstructed path for optical instruments; (3) provide access to the eye that allows for tool movement; (4) maintain eyeball hydration and improve the scan quality of an imaging system, such as an OCT system or a surgical microscope and may maintain or control an intraocular pressure of the eye to a stable, desired level during surgical procedures. |
| FILED | Tuesday, September 15, 2020 |
| APPL NO | 17/021925 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 90/20 (20160201) A61B 90/50 (20160201) Original (OR) Class A61B 2090/3735 (20160201) A61B 2217/005 (20130101) A61B 2217/007 (20130101) A61B 2562/0247 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/00736 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016779 | Lieberman et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Jay R. Lieberman (Los Angeles, California); William Pannell (Los Angeles, California); Yong Chen (Los Angeles, California); Xuan Song (Los Angeles, California); Sofia Bougioukli (Los Angeles, California) |
| ABSTRACT | A method for repairing a bone defect of a patient includes providing a ceramic scaffold configured for filling the bone defect, loading the scaffold with growth factor transduced cells incorporating a gene that encodes a growth factor essential for bone formation, placing the ceramic scaffold with the growth factor transduced cells in or across the bone defect, and stabilizing the ceramic scaffold with the growth factor transduced cells in the patient until the bone defect is healed. An assembly for repairing a bone defect includes a ceramic scaffold configured for spanning the bone defect and a culture of live growth factor transduced cells incorporating a gene that encodes a growth factor essential for bone formation loaded onto the ceramic scaffold. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 16/337893 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/28 (20130101) A61F 2/30942 (20130101) Original (OR) Class A61F 2002/30235 (20130101) A61F 2002/30677 (20130101) A61F 2002/30784 (20130101) A61F 2310/00293 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/1875 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/10 (20130101) A61L 27/54 (20130101) A61L 27/3834 (20130101) A61L 2300/414 (20130101) A61L 2430/02 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016834 | Avantaggiati et al. |
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| FUNDED BY |
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| APPLICANT(S) | GEORGETOWN UNIVERSITY (Washington, District of Columbia); GEORGE MASON UNIVERSITY (Fairfax, Virginia) |
| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia); George Mason University (Fairfax, Virginia) |
| INVENTOR(S) | Maria Laura Avantaggiati (Kensington, Maryland); Mikell Paige (Fairfax, Virginia) |
| ABSTRACT | Methods of treating or preventing cancer, diabetes, and/or obesity in a subject are provided. The methods comprise administering to a subject a therapeutically effective amount of an SLC25A1 inhibitor as described herein. Also provided herein are pharmaceutical compositions comprising an SLC25A1 inhibitor and a chemotherapeutic agent. Further provided herein are methods of inhibiting SLC25A1 in a cell. |
| FILED | Friday, August 03, 2018 |
| APPL NO | 16/636226 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016845 | Gavathiotis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York) |
| INVENTOR(S) | Evripidis Gavathiotis (Roslyn, New York); Denis E. Reyna (Bronx, New York); Felix Kopp (Brooklyn, New York); Ulrich Steidl (New Rochelle, New York) |
| ABSTRACT | Activators of BAX and their uses in cancer therapy are disclosed. |
| FILED | Tuesday, June 07, 2022 |
| APPL NO | 17/834087 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/427 (20130101) Original (OR) Class A61K 31/429 (20130101) A61K 31/437 (20130101) A61K 31/4439 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016853 | Lin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Belite Bio, Inc (Cayman Island, Cayman Islands); THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | Belite Bio, Inc (Grand Cayman, Cayman Islands); The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Yu-Hsin Tom Lin (San Diego, California); Cheng-Chi Irene Wang (San Diego, California); Konstantin Petrukhin (New Windsor, New York) |
| ABSTRACT | Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for the treatment of retinal binding protein (RBP4) related diseases, such as obesity and the like. |
| FILED | Monday, April 12, 2021 |
| APPL NO | 17/228590 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/519 (20130101) A61K 31/4545 (20130101) Original (OR) Class A61K 31/4985 (20130101) A61K 31/5365 (20130101) A61K 31/5383 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016863 | Plemper et al. |
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| FUNDED BY |
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| APPLICANT(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia); EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia State University Research Foundation, Inc. (Atlanta, Georgia); Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Richard Plemper (Atlanta, Georgia); Julien Sourimant (Atlanta, Georgia); Edgars Jecs (Decatur, Georgia); Dennis Liotta (Atlanta, Georgia); Stephen Pelly (Atlanta, Georgia); Robert Wilson (Ganesvoort, New York); Zackery Will Dentmon (East Point, Georgia) |
| ABSTRACT | Disclosed herein are compounds having antiviral activity, and, in particular, an inhibitory activity on the replication of Respiratory Syncytial Virus (RSV). Druggable target sites, including Px, in the RSV N protein are disclosed, as well as compounds targeting Px. The compounds can be used to treat patients with RSV infection. |
| FILED | Friday, May 03, 2019 |
| APPL NO | 17/052595 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Heterocyclic Compounds C07D 311/16 (20130101) C07D 311/18 (20130101) C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016864 | Clare et al. |
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| FUNDED BY |
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| APPLICANT(S) | ANOVIA BIOSCIENCES, INC. (New York, New York) |
| ASSIGNEE(S) | Anovia Biosciences, Inc. (New York, New York) |
| INVENTOR(S) | Michael Clare (Skokie, Illinois); Juan Du (Beijing, China PRC); Xiang Li (Beijing, China PRC); Ronggang Liu (Berwyn, Pennsylvania) |
| ABSTRACT | This invention relates to LOX enzyme-inhibiting compounds in accordance with Formula I or Formula II, or a pharmaceutically acceptable salt or hydrate thereof: and pharmaceutical compositions comprising the compounds. Such compounds and compositions can be useful in treating a variety of conditions, diseases, and disorders including, but not limited to, fibrotic disorders, proliferative disorders, cardiovascular disorders, acute and chronic inflammatory disorders, primary and metastatic cancer, pulmonary conditions, ocular diseases, and neurological and neuropsychiatric conditions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, October 28, 2022 |
| APPL NO | 18/265422 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/541 (20130101) Original (OR) Class A61K 31/5377 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016877 | Jamieson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Catriona Jamieson (San Diego, California); Raymond Diep (San Diego, California); Jane Isquith (San Diego, California); Qingfei Jiang (San Diego, California); Jessica Pham (San Diego, California) |
| ABSTRACT | In alternative embodiments, provided are compositions, including products of manufacture and kits, and methods, for treating or ameliorating a cancer by inhibiting expression or activity of Mouse Double Minute 2 homolog (MDM2), an APOBEC3G (A3G) protein, message (mRNA) or gene, and/or an ADAR1p150 protein, message (mRNA) or gene, e.g., by increasing the presence of in a cell or adding to a cell a molecule inhibitory to MDM2, APOBEC3G and/or ADAR1p150 expression, such as an miRNA that binds to MDM2, APOBEC3G and/or ADAR1p150 transcripts, or any molecule that can inhibit or destabilize the transcripts, resulting in decreased MDM2, APOBEC3G and/or ADAR1p150 expression, to treat a cancer such as leukemia, e.g., by inhibiting the propagation of a cancer cell, a leukemia cell, a leukemia stem cell (LSC) or a pre-leukemia cell stem cell (pre-LSC). |
| FILED | Wednesday, August 24, 2022 |
| APPL NO | 17/895007 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016884 | Cooper et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UNITED STATES DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Denise R. Cooper (St. Petersburg, Florida); Lisa Gould (Warwick, Rhode Island); Niketa Patel (Land O'Lakes, Florida); Mack Wu (Tampa, Florida) |
| ABSTRACT | Provided herein are exosomal compositions and exsosomal lncRNA compositions and formulations thereof. Also provided herein are methods of treating a wound in a subject in need thereof that can contain the step of administering an exosomal composition and/or exsosomal lncRNA compositions or formulation thereof to a wound in a subject in need thereof. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 16/329448 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 35/35 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0653 (20130101) C12N 5/0667 (20130101) C12N 15/113 (20130101) C12N 2310/20 (20170501) C12N 2310/111 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016892 | Hatfull et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Graham F. Hatfull (Pittsburgh, Pennsylvania); Carlos Andrés Guerrero (Pittsburgh, Pennsylvania); Rebekah Marie Dedrick (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed are pharmaceutical compositions comprising a combination of five or more phages and a pharmaceutically acceptable carrier, as well as methods of treating, reducing, or preventing a disease caused by Mycobacterium tuberculosis in a mammal, methods of treating an antibiotic resistant infection in a mammal, and methods of treating, reducing, or preventing activation of a latent disease caused by M. tuberculosis. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/716939 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0073 (20130101) A61K 35/76 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016896 | Lin et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Gang Lin (Forest Hills, New York); Carl Nathan (Larchmont, New York); Pradeep K. Singh (New York, New York) |
| ABSTRACT | The compounds of the present invention are represented by the following compounds having Formula I: where the substituents R1, R4, L, M, X, Y, and s are as defined herein. The compounds of the present invention are also represented by the following compounds having Formula (Ia), Formula (Ib), or Formula (Ic): where the substituents R1-R4, Rx, Ry, X, Y, and s are as defined herein. These compounds are used in the treatment of cancer, immunologic disorders, autoimmune disorders, neurodegenerative disorders, or inflammatory disorders or for providing immunosuppression for transplanted organs or tissues. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/532285 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/165 (20130101) A61K 38/02 (20130101) A61K 38/05 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 237/06 (20130101) C07C 237/12 (20130101) C07C 237/22 (20130101) C07C 271/22 (20130101) C07C 311/14 (20130101) C07C 311/19 (20130101) C07C 2601/02 (20170501) Heterocyclic Compounds C07D 209/18 (20130101) C07D 261/18 (20130101) Peptides C07K 5/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016899 | Hassan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Hatim A. Hassan (Chicago Ridge, Illinois); Donna Arvans (Chicago, Illinois) |
| ABSTRACT | Provided herein are compositions comprising Sel1-derived peptides thereof, and method of use thereof for the treatment/prevention excess oxalate levels and conditions and diseases related thereto. In particular, peptides comprise Sel-like repeat (SLR) domains and/or tetratricopeptide (TPR) domains and may be linked together or with other peptides or polypeptides to treat/prevent diseases/conditions related to excess oxalate levels, such as hyperoxaluria and/or hyperoxalemia. |
| FILED | Thursday, July 18, 2019 |
| APPL NO | 17/260690 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/08 (20180101) A61P 13/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016901 | Langer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Robert S. Langer (Newton, Massachusetts); Carlo Giovanni Traverso (Newton, Massachusetts); Junwei Li (Cambridge, Massachusetts); Thomas Wang (Cambridge, Massachusetts); Ameya R. Kirtane (Somerville, Massachusetts); Yunhua Shi (Arlington, Massachusetts) |
| ABSTRACT | The present disclosure provides compositions, methods, and kits that enable the in situ growth of polymers on or within a subject. In some aspects, the monomer, dopamine, polymerizes in vivo to form a polymer on a tissue. In additional aspects, the compositions, methods, and kits are useful for treating or preventing a disease or disorder. |
| FILED | Thursday, December 10, 2020 |
| APPL NO | 17/118521 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/495 (20130101) A61K 38/1787 (20130101) Original (OR) Class A61K 45/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/06 (20130101) A61L 24/08 (20130101) A61L 24/046 (20130101) A61L 27/16 (20130101) A61L 27/18 (20130101) A61L 27/20 (20130101) A61L 2300/254 (20130101) A61L 2300/256 (20130101) A61L 2300/438 (20130101) A61L 2400/04 (20130101) A61L 2430/06 (20130101) A61L 2430/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0065 (20130101) Enzymes C12Y 111/01006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016902 | Payne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LOMA LINDA UNIVERSITY (Loma Linda, California) |
| ASSIGNEE(S) | LOMA LINDA UNIVERSITY (Loma Linda, California) |
| INVENTOR(S) | Kimberly J. Payne (Loma Linda, California); Olivia L. Francis-Boyle (Loma Linda, California) |
| ABSTRACT | In one aspect, methods of treating a subject having a cancer that expresses a cytokine receptor are provided. In some embodiments, the method comprises administering to the subject a biologic agent in an amount sufficient to induce loss of cytokine receptor signaling through increased expression of a Suppressor of Cytokine Signaling genes and/or loss of one or more cytokine receptor components from the cancer cell surface. In some embodiments, the biologic agent is a cytokine or cytokine mimetic. |
| FILED | Wednesday, April 04, 2018 |
| APPL NO | 16/500194 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/19 (20130101) A61K 38/1808 (20130101) A61K 38/2046 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57411 (20130101) G01N 33/57423 (20130101) G01N 33/57426 (20130101) G01N 33/57449 (20130101) G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016915 | Oh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAYLOR RESEARCH INSTITUTE (Dallas, Texas) |
| ASSIGNEE(S) | BAYLOR RESEARCH INSTITUTE (Dallas, Texas) |
| INVENTOR(S) | SangKon Oh (Baltimore, Maryland); Dapeng Li (Davis, California); Jacques Banchereau (Montclair, New Jersey); Gerard Zurawski (Midlothian, Texas); Sandra Zurawski (Midlothian, Texas) |
| ABSTRACT | The present invention includes compositions and methods for making and using anti DC-ASGPR antibodies that can, e.g., activate DCs and other cells. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 17/454108 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 47/6849 (20170801) A61K 51/1027 (20130101) A61K 2039/5154 (20130101) Peptides C07K 14/005 (20130101) C07K 14/37 (20130101) C07K 14/195 (20130101) C07K 14/405 (20130101) C07K 14/435 (20130101) C07K 16/28 (20130101) C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/56 (20130101) C07K 2317/74 (20130101) C07K 2317/75 (20130101) C07K 2317/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0639 (20130101) C12N 7/00 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016935 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yongjian Liu (Chesterfield, Missouri); Robert Gropler (St. Louis, Missouri); Steven Brody (St. Louis, Missouri); Daniel Kreisel (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Yongjian Liu (Chesterfield, Missouri); Robert Gropler (St. Louis, Missouri); Steven Brody (St. Louis, Missouri); Daniel Kreisel (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of compositions of imaging agents and methods for use in detecting, monitoring, and evaluating CCR2 associated diseases, disorders, and conditions. |
| FILED | Tuesday, August 25, 2020 |
| APPL NO | 17/001857 |
| ART UNIT | RD00 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/02 (20130101) A61K 51/08 (20130101) Original (OR) Class A61K 51/088 (20130101) A61K 51/1244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016948 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Joseph Wang (San Diego, California); Liangfang Zhang (San Diego, California) |
| ABSTRACT | Disclosed are nano/micromotor devices, systems, and methods for providing payloads in the gastrointestinal system. In one aspect, a micromotor for a gastrointestinal tract includes a micromotor body including a one or more material layers to provide a structure that surrounds a hollow interior region and has an opening to an exterior of the micromotor body; one or more particles including a biocompatible metal element, the one or more particles contained in the interior region of the micromotor body; a coating coupled to the structure of the micromotor body; and a payload material, in which the micromotor is structured to move in a fluid of a gastrointestinal system based on a reaction between the one or more particles and a constituent or a condition of the fluid, such that the reaction generates bubbles that accelerate out of the opening of the micromotor body to propel the micromotor in the fluid. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 16/475894 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4222 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0007 (20130101) Original (OR) Class A61K 9/0053 (20130101) A61K 9/204 (20130101) A61K 9/205 (20130101) A61K 9/501 (20130101) A61K 9/2009 (20130101) A61K 9/2027 (20130101) A61K 9/2086 (20130101) A61K 9/4808 (20130101) A61K 9/4866 (20130101) A61K 9/5026 (20130101) A61K 9/5031 (20130101) A61K 9/5036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016974 | Handa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| ASSIGNEE(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| INVENTOR(S) | Hitesh Handa (Athens, Georgia); Marcus Goudie (Athens, Georgia) |
| ABSTRACT | Embodiments of the present disclosure provide for treated articles of tubing having anti-fouling characteristics, methods of making treated articles of tubing, and the like. Disclosed herein are treated articles of tubing impregnated with a silicone oil and a nitric oxide release agent. Also described are methods for preparing a treated article of tubing and methods for delivering a pharmaceutically acceptable fluid to a subject in need thereof, wherein the fluid is transferred from a fluid source through treated articles of tubing to the subject. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397488 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/06 (20130101) Original (OR) Class A61L 29/16 (20130101) A61L 29/085 (20130101) A61L 2300/114 (20130101) A61L 2420/06 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/046 (20200101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 183/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017029 | Tong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MORNINGSIDE VENTURE INVESTMENTS LIMITED (Monaco, Monaco) |
| ASSIGNEE(S) | Morningside Venture Investments Limited (Monaco, Monaco) |
| INVENTOR(S) | Ling-Kang Tong (Hayward, California); Daniela Tamar Buchman (Mountain View, California); Jackie Joe Hancock (Berkeley, California); Nicholas Terzulli (Oakland, California) |
| ABSTRACT | A two-part bioactive agent delivery system includes a disposable part, a reusable part, and a solvent removal element. The disposable part includes an agent reservoir, a transdermal patch communicating with the agent reservoir and adapted to transdermally deliver the bioactive agent to a user. The transdermal patch has a bottom surface adapted to contact skin of the user, a top surface opposite the bottom surface, and a gas permeable membrane disposed over the top surface of the transdermal patch. The reusable part includes a power source and control electronics that are adapted to deliver bioactive agent dissolved in a solvent from the agent reservoir to the transdermal patch. The solvent removal element includes a gap disposed between the disposable part and the reusable part to create a flow path for gaseous solvent to flow from the gas permeable membrane to ambient air around the bioactive agent delivery system. |
| FILED | Friday, March 03, 2023 |
| APPL NO | 18/178442 |
| ART UNIT | 3781 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 35/10 (20190501) Original (OR) Class A61M 2205/14 (20130101) A61M 2205/0272 (20130101) A61M 2205/8206 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017091 | Friedman |
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| FUNDED BY |
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| APPLICANT(S) | Integrated Sensors, LLC (Palm Beach Gardens, Florida) |
| ASSIGNEE(S) | Integrated Sensors, LLC (Palm Beach Gardens, Florida) |
| INVENTOR(S) | Peter S. Friedman (Palm Beach Gardens, Florida) |
| ABSTRACT | Embodiments are directed generally to an ionizing-radiation beamline monitoring system that includes a vacuum chamber structure with vacuum compatible flanges through which an incident ionizing-radiation beam enters the monitoring system. Embodiments further include at least one scintillator within the vacuum chamber structure that can be at least partially translated in the ionizing-radiation beam while oriented at an angle greater than 10 degrees to a normal of the incident ionizing-radiation beam, a machine vision camera coupled to a light-tight structure at atmospheric/ambient pressure that is attached to the vacuum chamber structure by a flange attached to a vacuum-tight viewport window with the camera and lens optical axis oriented at an angle of less than 80 degrees with respect to a normal of the scintillator, and at least one ultraviolet (“UV”) illumination source facing the scintillator in the ionizing-radiation beam for monitoring a scintillator stability comprising scintillator radiation damage. |
| FILED | Thursday, September 07, 2023 |
| APPL NO | 18/462606 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101) A61N 5/1045 (20130101) A61N 5/1048 (20130101) A61N 5/1049 (20130101) A61N 5/1064 (20130101) A61N 5/1067 (20130101) Original (OR) Class A61N 5/1077 (20130101) A61N 2005/1059 (20130101) A61N 2005/1087 (20130101) Measurement of Nuclear or X-radiation G01T 1/29 (20130101) G01T 1/40 (20130101) G01T 1/1612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017195 | Qing et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Quan Qing (Chandler, Arizona); Ching-wei Tsao (Tempe, Arizona); Peiming Zhang (Gilbert, Arizona) |
| ABSTRACT | The present disclosure provides an apparatus for synthesizing a biopolymer, a method for preparing an apparatus for synthesizing a biopolymer, and a method of synthesizing a biopolymer. The apparatus comprises (a) a substrate comprising atop surface and a plurality of wells, wherein each of the plurality of wells comprises a first electrode disposed on the bottom of the well and a linker attached to the sides of the well; and (b) a fluidic chamber system disposed on the top surface of the substrate. |
| FILED | Monday, July 01, 2019 |
| APPL NO | 17/257816 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 19/0093 (20130101) Original (OR) Class B01J 2219/00317 (20130101) B01J 2219/00529 (20130101) B01J 2219/00596 (20130101) B01J 2219/00653 (20130101) B01J 2219/00659 (20130101) B01J 2219/00713 (20130101) B01J 2219/00722 (20130101) B01J 2219/00822 (20130101) B01J 2219/00853 (20130101) B01J 2219/00855 (20130101) Peptides C07K 1/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017210 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Eun Sok Kim (Rancho Palos Verdes, California); Yongkui Tang (Pasadena, California); Xuelian Chen (Alhambra, California); Jiang F. Zhong (Temple City, California) |
| ABSTRACT | A device for contactless, damage-free, high-precision cell and/or particle extraction and transfer through acoustic droplet ejection includes a substrate having a first surface and a second surface and a focused ultrasonic transducer positioned to focus an acoustic wave onto the substrate such that a droplet that includes at least one cell or particle is ejected from the bulk or from the first surface per each actuation of the focused ultrasonic transducer through droplet ejection. The substrate includes cells or particles inside the substrate or on top of the substrate. The focused ultrasonic transducer includes a piezoelectric substrate having a top face and a bottom face, a Fresnel acoustic lens including a plurality of annular rings of air cavities disposed on the top face, and a first patterned circular electrode disposed over the top face and a second patterned circular electrode disposed over the bottom face. The first patterned circular electrode overlaps the second patterned circular electrode. |
| FILED | Friday, May 21, 2021 |
| APPL NO | 17/327431 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/0268 (20130101) Original (OR) Class B01L 2400/0436 (20130101) B01L 2400/0439 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0696 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017436 | Bottlang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WAVECEL, LLC (Wilsonville, Oregon) |
| ASSIGNEE(S) | WAVECEL, LLC (Wilsonville, Oregon) |
| INVENTOR(S) | Michael Bottlang (Happy Valley, Oregon); Jeffrey Bennett (Portland, Oregon) |
| ABSTRACT | An impact-absorbing structure that includes a plurality of interconnected cells forming a sheet, each cell having a sidewall and a longitudinal axis. Each cell may be configured to absorb energy through plastic deformation in response to an applied load, and a sidewall of at least one cell may include a geometric perturbation that is oriented in a direction that is not parallel to the longitudinal axis of the cell. The geometric perturbation may reduce the load required to cause plastic deformation of the cell. |
| FILED | Thursday, January 27, 2022 |
| APPL NO | 17/586246 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Hats; Head Coverings A42B 3/065 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/12 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Springs; Shock-absorbers; Means for Damping Vibration F16F 7/121 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017994 | Tavares et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SYMBERIX, INC. (Durham, North Carolina) |
| ASSIGNEE(S) | Symberix, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Francis X. Tavares (Durham, North Carolina); Bret D. Wallace (Durham, North Carolina); Ward Peterson (Morrisville, North Carolina) |
| ABSTRACT | The present disclosure describes compounds and compositions that inhibit β-glucuronidase activity, and methods for attenuating the side effects of one or more drugs and improving the efficacy of drugs by administration of selective β-glucuronidase inhibitors. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/959491 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/12 (20180101) Heterocyclic Compounds C07D 215/227 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018003 | Ojima et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Iwao Ojima (Port Jefferson, New York); Vincent Alford (Sunnyvale, California); Anushree Kamath (Issaquah, Washington); Jian Cao (S. Setauket, New York); Xiadong Ren (Port Jefferson Station, New York); Nicole Sampson (Setauket, New York); Monaf Awwa (Bel Air, Maryland) |
| ABSTRACT | The invention relates to substituted pyrimidine compounds with the following formula: or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof. These compounds selectively target the hemopexin domain of matrix metalloproteinase 9 (MMP-9) and do not inhibit the protease's catalytic functions. The invention also relates to methods of treating cancer in a patient in need thereof with the compounds. |
| FILED | Monday, June 21, 2021 |
| APPL NO | 17/353075 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 239/56 (20130101) C07D 239/95 (20130101) Original (OR) Class C07D 403/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018004 | Cisar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. Lundbeck A/S (Valby, Denmark); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | H. LUNDBECK A/S (Valby, Denmark); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Justin S. Cisar (San Diego, California); Cheryl A. Grice (Redwood City, California); Todd K. Jones (Solana Beach, California); Micah J. Niphakis (San Diego, California); Jae Won Chang (San Diego, California); Kenneth M. Lum (San Diego, California); Benjamin F. Cravatt (San Diego, California) |
| ABSTRACT | This disclosure provides compounds and compositions which may be modulators of MAGL and/or ABHD6 and their use as medicinal agents, processes for their preparation, and pharmaceutical compositions that include disclosed compounds as at least one active agent. The disclosure also provides for method of treating a patient in need thereof, where the patient is suffering from post-traumatic stress disorder comprising administering a disclosed compound or composition. |
| FILED | Tuesday, November 08, 2022 |
| APPL NO | 18/053582 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/22 (20180101) Acyclic or Carbocyclic Compounds C07C 271/10 (20130101) C07C 271/12 (20130101) Heterocyclic Compounds C07D 205/04 (20130101) C07D 207/09 (20130101) C07D 207/14 (20130101) C07D 213/38 (20130101) C07D 213/40 (20130101) C07D 213/55 (20130101) C07D 215/42 (20130101) C07D 215/46 (20130101) C07D 231/12 (20130101) C07D 231/16 (20130101) C07D 231/56 (20130101) C07D 241/04 (20130101) C07D 261/08 (20130101) C07D 263/32 (20130101) C07D 271/06 (20130101) C07D 295/26 (20130101) C07D 295/205 (20130101) Original (OR) Class C07D 307/79 (20130101) C07D 317/46 (20130101) C07D 317/58 (20130101) C07D 401/04 (20130101) C07D 401/10 (20130101) C07D 403/10 (20130101) C07D 405/14 (20130101) C07D 407/06 (20130101) C07D 413/06 (20130101) C07D 413/10 (20130101) C07D 471/04 (20130101) C07D 471/10 (20130101) C07D 487/04 (20130101) C07D 491/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018045 | Sayers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland); Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Thomas J. Sayers (Boonsboro, Maryland); Poonam Tewary (Frederick, Maryland); Leslie Gunatilaka (Tucson, Arizona); Alan D. Brooks (Frederick, Maryland); Kithsiri Wijeratne (Tucson, Arizona); Yaming Xu (Tucson, Arizona) |
| ABSTRACT | Disclosed are compounds suitable for enhancing cancer treatment, for example, a compound of formula (I): (I) wherein R1 is as defined herein. Also disclosed is a method of enhancing the response of cancer cells in a mammal to treatment with an apoptosis inducing ligand, a method of inducing apoptosis in cancer cells in a mammal, and a method of treating prostate cancer in mammal in need thereof comprising administration of a compound described herein. |
| FILED | Wednesday, March 06, 2019 |
| APPL NO | 16/978442 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Steroids C07J 71/001 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018050 | Agbandje-McKenna et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Mavis Agbandje-McKenna (Gainesville, Florida); Mario Mietzsch (Gainesville, Florida) |
| ABSTRACT | This disclosure relates to variant AAVrh 10 particles engineered to escape host neutralizing antibodies but retain or improve transduction efficiency, and their use as gene delivery vehicles. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/359324 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2015/8518 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018051 | Collins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter Collins (Silver Spring, Maryland); Bo Liang (Boyds, Maryland); Shirin Munir (Potomac, Maryland); Anne Schaap Nutt (Austin, Texas); Ursula Buchholz (Silver Spring, Maryland); Natalie Mackow (East Setauket, New York); Peter Kwong (Washington, District of Columbia); Barney Graham (Smyrna, Georgia); Jason McLellan (Austin, Texas) |
| ABSTRACT | Recombinant paramyxoviruses including a viral genome encoding a heterologous gene are provided. In several embodiments, the recombinant paramyxovirus is a recombinant parainfluenza virus, such as a recombinant PIV3 including a viral genome encoding a heterologous respiratory syncytial virus F ectodomain linked to the transmembrane domain and the cytoplasmic tail of the F protein from the PIV3. Nucleic acid molecules including the genome of a recombinant paramyxoviruses are also provided. The recombinant viruses may advantageously be used in vaccine formulations, such as for vaccines against parainfluenza virus and respiratory syncytial virus. |
| FILED | Tuesday, January 31, 2023 |
| APPL NO | 18/162530 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/155 (20130101) A61K 2039/70 (20130101) A61K 2039/575 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/03 (20130101) C07K 2319/033 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/00022 (20130101) C12N 2760/18534 (20130101) C12N 2760/18571 (20130101) C12N 2760/18622 (20130101) C12N 2760/18634 (20130101) C12N 2760/18641 (20130101) C12N 2760/18643 (20130101) C12N 2760/18671 (20130101) C12N 2760/18722 (20130101) C12N 2760/18734 (20130101) C12N 2760/18741 (20130101) C12N 2760/18743 (20130101) C12N 2760/18771 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018058 | Borkan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Boston Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Boston Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Steven C. Borkan (Medfield, Massachusetts); Zhiyong Wang (Cambridge, Massachusetts) |
| ABSTRACT | One aspect of the technology relates to methods, assays and kits to identify ischemia and ischemic injury, including kidney injury, and are useful in determining efficacy of cancer treatments. In particular, differential phosphorylation of the nucleophosmin (NPM) polypeptide is an early marker of ischemic injuries such as kidney injury, AKI and ischemic renal cell injury. Another aspect of the technology relates to compositions and methods for the treatment of ischemia and kidney injury, including NPM inhibitory agents, including, but not limited to NPM inhibitory peptides for the treatment of ischemia and kidney injury. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 17/459680 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) A61P 13/12 (20180101) Peptides C07K 14/47 (20130101) C07K 14/4703 (20130101) Original (OR) Class C07K 2319/09 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) G01N 33/6875 (20130101) G01N 33/54306 (20130101) G01N 2440/14 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018067 | Chan-Hui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Theraclone Sciences, Inc. (Seattle, Washington); International AIDS Vaccine Initiative, Inc. (New York, New York); The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | International AIDS Vaccine Initiative, Inc. (New York, New York); The Scripps Research Institute (La Jolla, California); Theraclone Sciences, Inc. (Seattle, Washington) |
| INVENTOR(S) | Po-Ying Chan-Hui (Bellevue, Washington); Steven Frey (Redmond, Washington); Ole Olsen (Everett, Washington); Jennifer Mitcham (Redmond, Washington); Matthew Moyle (Redmond, Washington); Sanjay K. Phogat (Frederick, Maryland); Dennis R. Burton (La Jolla, California); Laura Marjorie Walker (San Diego, California); Pascal Raymond Georges Poignard (San Diego, California); Wayne Koff (Stony Brook, New York); Melissa Danielle De Jean De St. Marcel Simek-Lemos (Brooklyn, New York); Stephen Kaminsky (Bronx, New York) |
| ABSTRACT | The invention provides a method for obtaining a broadly neutralizing antibody (bNab), including screening memory B cell cultures from a donor PBMC sample for neutralization activity against a plurality of HIV-1 species, cloning a memory B cell that exhibits broad neutralization activity; and rescuing a monoclonal antibody from that memory B cell culture. The resultant monoclonal antibodies are characterized by their ability to selectively bind epitopes from the Env proteins in native or monomeric form, as well as to inhibit infection of HIV-1 species from a plurality of clades. Compositions containing human monoclonal anti-HIV antibodies used for prophylaxis, diagnosis and treatment of HIV infection are provided. Methods for generating such antibodies by immunization using epitopes from conserved regions within the variable loops of gp120 are provided. Immunogens for generating anti-HIV1 bNAbs are also provided. Furthermore, methods for vaccination using suitable epitopes are provided. |
| FILED | Friday, January 06, 2023 |
| APPL NO | 18/150957 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/1045 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018077 | Sadelain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York); THE U.S.A. AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Michel Sadelain (New York, New York); Reuben Benjamin (London, United Kingdom); Dimiter S. Dimitrov (Frederick, Maryland); Yang Feng (Frederick, Maryland) |
| ABSTRACT | The presently disclosed subject matter provides for methods and compositions for treating cancer (e.g., multiple myeloma). It relates to anti-CD56 antibodies, chimeric antigen receptors (CARs) that specifically target human CD56, and immunoresponsive cells comprising such CARs. The presently disclosed CD56-specific CARs have enhanced immune-activating properties, including anti-tumor activity. |
| FILED | Thursday, June 25, 2020 |
| APPL NO | 16/912291 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/3061 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/30 (20130101) C07K 2317/54 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018080 | Suva et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Mario Suva (Boston, Massachusetts); Kai Wucherpfennig (Boston, Massachusetts); Aviv Regev (Cambridge, Massachusetts); Itay Tirosh (Cambridge, Massachusetts); Nathan D. Mathewson (Boston, Massachusetts) |
| ABSTRACT | Provided are methods and compositions for treating cancer in a subject in need thereof. One of the top gene products in glioblastoma multiforme (GBM) is KLRB1 (also known as CD161), a C-type lectin protein that binds to CLEC2D. Binding of CLEC2D to the KLRB1 receptor inhibits the cytotoxic function of NK cells as well as cytokine secretion. KLRB1 is only expressed by small subpopulations of human blood T cells, and consequently little is known about the function of this receptor in T cells. However, preliminary data demonstrate that KLRB1 expression is induced in T cells within the GBM microenvironment. In an exemplary embodiment, a method is provided comprising administering an agent capable of blocking the interaction of KLRB1 with its ligand. The agent may comprise an antibody or fragment thereof, which may bind KLRB1 or CLEC2D. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/763834 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 35/17 (20130101) A61K 38/465 (20130101) A61K 39/0011 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 48/0016 (20130101) A61K 2039/51 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2851 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/75 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/22 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018081 | Goodwin et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Andrew P. Goodwin (Boulder, Colorado); Jennifer N. Cha (Boulder, Colorado); Shambojit Roy (Boulder, Colorado); Michael D. Brasino (Portland, Oregon) |
| ABSTRACT | A prodrug enzyme covalently photoconjugated to a live cell receptor survives endosomal proteolysis and retains its catalytic activity on the living cell membrane over multiple days. Antibody-directed enzyme prodrug therapy is a promising approach for selective treatment of solid tumors, but methods are needed to preserve enzyme activity on living cell membranes over multiple prodrug dosings. A fusion protein was designed with both an anti-epidermal growth factor receptor (EGFR) affibody and the prodrug enzyme cytosine deaminase, which can convert prodrug 5-fluorocytosine to the anticancer drug 5-fluorouracil. A benzophenone group was added at a site-specific mutation within the affibody portion, and the fusion protein was selectively and irreversibly photoconjugated to EGFR receptors expressed on membranes of live MDA-MB-468 breast cancer cells. Affinity-mediated covalent conjugation of the affibody-enzymes to cell receptors allows for prolonged expression on membranes and retained enzymatic activity without genetic engineering. |
| FILED | Friday, August 28, 2020 |
| APPL NO | 17/006635 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/16 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/2863 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/78 (20130101) Enzymes C12Y 305/04001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018082 | Butte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Manish J. Butte (Los Angeles, California); Maria I. Garcia-Lloret (Los Angeles, California) |
| ABSTRACT | Methods are described for treating systemic fungal and mycobacterial infections by treatment to enhances a Th1 response, reduces a Th2 response, or the combination thereof. Agents that antagonize the IL-4, the IL-13 receptor, or the combination thereof achieve the desired results. |
| FILED | Tuesday, September 15, 2020 |
| APPL NO | 17/021280 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/217 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) Peptides C07K 16/2866 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018086 | McGovern et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Dermot McGovern (Los Angeles, California); Stephan R. Targan (Santa Monica, California); Dalin Li (Walnut, California) |
| ABSTRACT | The aspects disclosed herein describe methods of identifying a subject that is non-responsive to anti-TNF therapy. The aspects disclosed herein further provide for a method of selecting a therapy for a subject with Inflammatory Bowel Disease (IBD), and treating the subject with the therapy. |
| FILED | Friday, October 22, 2021 |
| APPL NO | 17/508128 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 39/39541 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) Peptides C07K 16/241 (20130101) C07K 16/2875 (20130101) Original (OR) Class C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) G01N 33/6863 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) G01N 2800/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018092 | Bilgicer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame Du Lac (South Bend, Indiana) |
| INVENTOR(S) | Zihni Basar Bilgicer (South Bend, Indiana); Peter Edward Deak (South Bend, Indiana); Tanyel Kiziltepe Bilgicer (South Bend, Indiana); Michael William Handlogten (South Bend, Indiana); Jonathan Darryl Ashley (South Bend, Indiana) |
| ABSTRACT | The invention provides a strategy for site specific covalent modification of antibodies using a specialized targeting covalent heterobivalent ligand (cHBL), and corresponding design for a covalent heterobivalent inhibitor (cHBI) that can be used to prevent Immunoglobulin E (IgE) mediated allergic reactions triggered by drug molecules, according to one embodiment. These molecules contain four important components: (1) an IgE antigen binding site (ABS) ligand that can be a mimotope for the allergen protein, a small molecule, or a peptidomimetic, (2) an appropriate linker, which can be any flexible or rigid chemical linker, providing spacing between the ABS binder and the other moieties, (3) a nucleotide binding site (NBS) ligand, and (4) a reactive moiety to form a covalent link with an amino acid side chain of target IgE antibodies. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/126466 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 38/05 (20130101) A61K 38/07 (20130101) A61K 47/02 (20130101) A61K 47/10 (20130101) A61K 47/54 (20170801) A61K 47/62 (20170801) Peptides C07K 16/46 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018095 | Endo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Astellas Pharma Inc. (Tokyo, Japan); National Center for Global Health and Medicine (Tokyo, Japan); Hiroshima University (Higashihiroshima, Japan) |
| ASSIGNEE(S) | Astellas Pharma Inc. (Tokyo, Japan); National Center for Global Health and Medicine (Tokyo, Japan); Hiroshima University (Hiroshima, Japan) |
| INVENTOR(S) | Hideki Endo (Tokyo, Japan); Yukihito Ishizaka (Tokyo, Japan); Akira Ishiguro (Tokyo, Japan); Tomoki Takashina (Tokyo, Japan); Takashi Yamamoto (Hiroshima, Japan); Tetsushi Sakuma (Hiroshima, Japan) |
| ABSTRACT | An object of the present invention is to provide a cell penetrating peptide having a penetrating ability into cells. The present inventors provided a cell penetrating peptide consisting of the amino acid sequence of SEQ ID NO: 1, a cell penetrating peptide consisting of the amino acid sequence of SEQ ID NO: 2 and a cell penetrating peptide consisting of the amino acid sequence of SEQ ID NO: 3; and a complex comprising any one of the cell penetrating peptide and a functional molecule. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/854647 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018250 | Johnston |
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| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Center (Seattle, Washington) |
| ASSIGNEE(S) | FRED HUTCHINSON CANCER CENTER (Seattle, Washington) |
| INVENTOR(S) | Christopher D. Johnston (Seattle, Washington) |
| ABSTRACT | The present invention features modified polynucleotide sequences that mimic host cell DNA and methods of using such sequences for the genetic engineering of bacteria that are otherwise genetically intractable. |
| FILED | Friday, October 13, 2017 |
| APPL NO | 16/341290 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/09 (20130101) C12N 15/10 (20130101) C12N 15/11 (20130101) C12N 15/64 (20130101) C12N 15/74 (20130101) C12N 15/102 (20130101) C12N 15/113 (20130101) C12N 15/1027 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/33 (20130101) C12N 2310/333 (20130101) C12N 2330/50 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 2600/154 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018258 | Peters et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CZ Biohub SF, LLC (San Francisco, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | CZ Biohub SF, LLC (San Francisco, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jason Peters (Madison, Wisconsin); Carol Gross (Berkeley, California); Oren Rosenberg (San Francisco, California); Neha Prasad (San Francisco, California) |
| ABSTRACT | Described in this disclosure are CRISPRi systems and methods, along with the related compositions and kits, that combine modularity, stable genomic integration, and ease of transfer to diverse bacteria by conjugation. CRISPRi compositions, methods, systems and kits described herein allow for genetic dissection of bacteria, facilitating analyses of microbiome function, antibiotic resistances and sensitivities, as well as comprehensive screening for host-microbe interactions. Embodiments of the invention comprise compositions, methods, systems, and kits for CRISPRi-based repression of gene expression in bacteria. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/012486 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/70 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018272 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Prashant G. Mali (La Jolla, California); Luhan Yang (Somerville, Massachusetts) |
| ABSTRACT | A method of altering a eukaryotic cell is provided including transfecting the eukaryotic cell with a nucleic acid encoding RNA complementary to genomic DNA of the eukaryotic cell, transfecting the eukaryotic cell with a nucleic acid encoding an enzyme that interacts with the RNA and cleaves the genomic DNA in a site specific manner, wherein the cell expresses the RNA and the enzyme, the RNA binds to complementary genomic DNA and the enzyme cleaves the genomic DNA in a site specific manner. |
| FILED | Thursday, April 06, 2023 |
| APPL NO | 18/296579 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/01 (20130101) C12N 15/10 (20130101) C12N 15/63 (20130101) C12N 15/81 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 15/87 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/907 (20130101) C12N 15/1024 (20130101) C12N 15/8201 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) C12N 2810/55 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018275 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Le Cong (Cambridge, Massachusetts); Fei Ran (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for delivery, engineering and optimization of systems, methods, and compositions for manipulation of sequences and/or activities of target sequences. Provided are delivery systems and tissues of organ which are targeted as sites for delivery. Also provided are vectors and vector systems some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. Also provide dare methods of directing CRISPR complex formation in eukaryotic cells to ensure enhanced specificity for target recognition and avoidance of toxicity and to edit or modify a target site in a genomic locus of interest to alter or improve the status of a disease or a condition. |
| FILED | Tuesday, February 25, 2020 |
| APPL NO | 16/800988 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/052 (20130101) A01K 2227/105 (20130101) A01K 2267/0312 (20130101) A01K 2267/0331 (20130101) A01K 2267/0362 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 48/0058 (20130101) A61K 48/0091 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/86 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 15/1082 (20130101) C12N 2710/24144 (20130101) C12N 2740/15043 (20130101) C12N 2750/14132 (20130101) C12N 2750/14143 (20130101) C12N 2750/14152 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018279 | Park et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Sunghee Estelle Park (Philadelphia, Pennsylvania); Wenli Yang (Media, Pennsylvania); Dwight E. Stambolian (Monroeville, New Jersey); Dongeun Huh (Villanova, Pennsylvania) |
| ABSTRACT | This present disclosure relates to a bioengineering approach based on microphysiological culture to mimic tissue-tissue interface. Accordingly, the present disclosure provides methods, compositions and kits related to the approach. |
| FILED | Monday, October 19, 2020 |
| APPL NO | 17/074074 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/52 (20130101) C07K 14/75 (20130101) C07K 14/472 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) Original (OR) Class C12N 2500/05 (20130101) C12N 2513/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018286 | Wessely et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | Oliver Wessely (Cleveland Heights, Ohio); Uyen Wessely (Cleveland Heights, Ohio); Jan Jensen (Shaker Heights, Ohio); Michael Bukys (Cleveland, Ohio) |
| ABSTRACT | Provided herein are compositions, systems, kits, and methods for generating human podocyte cells by contacting human nephron progenitor cells with an FGFR pathway inhibitor, a BMP pathway inhibitor, and a WNT pathway inhibitor. In certain embodiments, the nephron progenitor cells are further contacted with at least one factor selected from: BMP4, BMP7, lysophosphatidic acid, and gamma-secretase inhibitor XX. In certain embodiments, the contacting the nephron progenitor cells is performed under serum-free conditions. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/012651 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0684 (20130101) Original (OR) Class C12N 2500/90 (20130101) C12N 2501/42 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2501/999 (20130101) C12N 2506/25 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018291 | Clark et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Edward Clark (Seattle, Washington); Jay Wesley Chaplin (Seattle, Washington) |
| ABSTRACT | The present invention provides compositions of CD 180 targeting molecules coupled to heterologous antigens, and their use in treating and/or limiting disease. |
| FILED | Friday, December 09, 2022 |
| APPL NO | 18/063823 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/29 (20130101) A61K 39/385 (20130101) A61K 47/6811 (20170801) A61K 47/6849 (20170801) A61K 2039/6056 (20130101) A61K 2039/55511 (20130101) A61K 2039/55561 (20130101) Peptides C07K 16/2896 (20130101) C07K 2319/40 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2770/24132 (20130101) C12N 2770/24134 (20130101) C12N 2770/28033 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018297 | Xu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Jie Xu (Troy, Michigan); Jifeng Zhang (Ann Arbor, Michigan); Yuqing Eugene Chen (Superior Township, Michigan); Dongshan Yang (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein is technology relating to molecular biological manipulation of genes and genomes and particularly, but not exclusively, to CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) methods, compositions, systems, and kits for improved genetic editing. |
| FILED | Monday, May 06, 2019 |
| APPL NO | 17/258776 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2207/05 (20130101) A01K 2217/072 (20130101) Peptides C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/102 (20130101) C12N 15/111 (20130101) C12N 15/8509 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018314 | Selvaraj et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arima Genomics, Inc. (Carlsbad, California) |
| ASSIGNEE(S) | Arima Genomics, Inc. (Carlsbad, California) |
| INVENTOR(S) | Siddarth Selvaraj (San Diego, California); Nathaniel Heintzman (San Diego, California); Christian Edgar Laing (San Diego, California) |
| ABSTRACT | The present disclosure relates to methods to deconvolute a mixture sample of genetic material from different origins or sources. The disclosed methods can be used in various applications, including, the non-invasive determination of a fetal genome, a fetal -ome (e.g. exome). or other targeted fetal locus from cell-free nucleic acids in maternal plasma or other body fluids; the determination of cancer-associated mutations from cell-free nucleic acids in a body fluid sample that contains a mixture of nucleic acids from normal cells and tumor cells; and quantification of donor cell contamination using a body fluid from a transplantation recipient to monitor and/or predict the outcome of a transplantation procedure. |
| FILED | Monday, July 04, 2016 |
| APPL NO | 15/738871 |
| ART UNIT | 1672 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/10 (20190201) G16B 20/20 (20190201) G16B 20/40 (20190201) G16B 40/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018317 | Blattman et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Joseph Blattman (Scottsdale, Arizona); Louis Schoettle (Tempe, Arizona) |
| ABSTRACT | Methods for incorporation of unique bowtie-barcodes into a nucleic acid origami nanostructure (FIG. 1). In particular, provided herein are methods that facilitate pairing and analysis of nucleic acids from individual cells using, for example, high-throughput next-generation sequencing. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 17/546953 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2563/159 (20130101) C12Q 2563/179 (20130101) C12Q 2565/133 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018320 | Rao et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The Children's Medical Center Corporation (Boston, Massachusetts); The United States of America, As Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Anjana Rao (La Jolla, California); Mamta Tahiliani (New York, New York); Kian Peng Koh (Jamaica Plain, Massachusetts); Suneet Agarwal (Belmont, Massachusetts); Aravind Iyer (Bethesda, Maryland) |
| ABSTRACT | The present invention provides for novel methods for regulating and detecting the cytosine methylation status of DNA. The invention is based upon identification of a novel and surprising catalytic activity for the family of TET proteins, namely TET1, TET2, TET3, and CXXC4. The novel activity is related to the enzymes being capable of converting the cytosine nucleotide 5-methylcytosine into 5-hydroxymethylcytosine by hydroxylation. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675502 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1007 (20130101) C12N 2501/70 (20130101) C12N 2501/71 (20130101) C12N 2501/724 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6869 (20130101) C12Q 2521/531 (20130101) C12Q 2521/531 (20130101) C12Q 2522/10 (20130101) C12Q 2522/10 (20130101) C12Q 2537/164 (20130101) C12Q 2537/164 (20130101) C12Q 2600/154 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018327 | Lynch et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Susan V. Lynch (Piedmont, California); Sophia Rose Levan (Oakland, California) |
| ABSTRACT | Provided herein are, inter alia, methods and kits for detecting epoxide hydrolase genes. In embodiments, methods and kits for detecting the risk of developing atopy or asthma are included. Also included are methods for preventing or treating atopy or asthma. |
| FILED | Friday, March 01, 2019 |
| APPL NO | 16/976285 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/58 (20130101) A61K 31/59 (20130101) A61K 31/201 (20130101) A61K 31/495 (20130101) A61K 35/60 (20130101) A61K 35/741 (20130101) A61K 35/745 (20130101) Peptides C07K 16/283 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 20/10 (20180101) G16H 50/30 (20180101) G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018330 | Issa et al. |
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| FUNDED BY |
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| APPLICANT(S) | Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Jean-Pierre J. Issa (Philadelphia, Pennsylvania); Jumpei Yamazaki (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention provides AML-specific methylation biomarkers (SP140, MCCC1, EHMT1 and MTSS1). In one embodiment, a biomarker is differentially methylated, specifically in AML. |
| FILED | Wednesday, October 19, 2016 |
| APPL NO | 15/769157 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/154 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57426 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018332 | Goggins et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Michael Goggins (Baltimore, Maryland); Tatsuo Hata (Sendai, Japan) |
| ABSTRACT | Described are telomere fusion assays to detect dysplasia in subjects using nested primers. The methods of the present invention are able to detect dysplasia in subjects with intraductal papillary mucinous neoplasma (IPMNs), for example. |
| FILED | Monday, September 24, 2018 |
| APPL NO | 16/648847 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019072 | Rissin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Quanterix Corporation (Billerica, Massachusetts) |
| ASSIGNEE(S) | Quanterix Corporation (Billerica, Massachusetts) |
| INVENTOR(S) | David M. Rissin (Somerville, Massachusetts); David Fournier (Northborough, Massachusetts); David C. Duffy (Arlington, Massachusetts); David R. Walt (Boston, Massachusetts); Cheuk W Kan (Waltham, Massachusetts) |
| ABSTRACT | Described herein are systems and methods for extending the dynamic range of assay methods and systems used for determining the concentration of analyte molecules or particles in a fluid sample. In some embodiments, a method comprises spatially segregating a plurality of analyte molecules in a fluid sample into a plurality of locations. At least a portion of the locations may be addressed to determine the percentage of said locations containing at least one analyte molecule. Based at least in part on the percentage, a measure of the concentration of analyte molecules in the fluid sample may be determined using an analog, intensity-based detection/analysis method/system and/or a digital detection/analysis method/system. In some cases, the assay may comprise the use of a plurality of capture objects. |
| FILED | Tuesday, March 23, 2021 |
| APPL NO | 17/210258 |
| ART UNIT | 1678 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6452 (20130101) G01N 33/573 (20130101) Original (OR) Class G01N 33/54313 (20130101) G01N 33/54366 (20130101) G01N 2201/062 (20130101) G01N 2333/924 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019081 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky); New York University (New York, New York) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky); New York University (New York, New York) |
| INVENTOR(S) | Qingjun Wang (Lexington, Kentucky); Beatrix M. Ueberheide (New York, New York) |
| ABSTRACT | A compound and a method of detecting CLN3 are provided. The compound includes a heavy isotope labeled CLN3 proteotypic peptide. The method includes i) selecting a CLN3 proteotypic peptide that exhibits linear behavior in the mass spectrometer; ii) generating a stable isotope labeled standard; iii) spiking known amounts of the stable isotope labeled standard into a sample to form a spiked sample; iv) determining retention times and establishing calibration curves using the spiked sample; and v) detecting unlabeled selected CLN3 proteins in the sample. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/521788 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/7233 (20130101) G01N 33/58 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2458/15 (20130101) G01N 2496/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019127 | Knappe et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yoshio Okada (Brookline, Massachusetts); The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, body corporate (Denver, Colorado); Moment Technologies, LLC (Brookline, Maine) |
| INVENTOR(S) | Svenja Knappe (Boulder, Colorado); Yoshio Okada (Brookline, Massachusetts); Sean Krzyzewski (Boulder, Colorado) |
| ABSTRACT | A magnetographic camera may be based on an optically pumped magnetometer (OPM). The magnetographic camera may measure a spatial distribution of magnetic field produced by a sample that may be stationary in time or may dynamically vary with time. The magnetographic camera may include a magnetic field detector housing containing a vapor cell. The magnetographic camera may include a laser light source to illuminate the vapor cell causing a magnetic field image of a sample to be generated. The magnetographic camera may include an optical detector to encode and store the magnetic field image of the sample that is spatially encoded as a distribution of light. |
| FILED | Thursday, November 21, 2019 |
| APPL NO | 17/296179 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) Original (OR) Class G01R 33/246 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019133 | Murphy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Matthew C. Murphy (Rochester, Minnesota); Joshua D. Trzasko (Rochester, Minnesota); Richard L. Ehman (Rochester, Minnesota); John Huston, III (Rochester, Minnesota); Armando Manduca (Rochester, Minnesota); Jonathan M. Scott (Rochester, Minnesota) |
| ABSTRACT | In accordance with some embodiments, systems, methods, and media for estimating a mechanical property based on a transformation of magnetic resonance elastography (MRE) data using a trained artificial neural network are provided. In some embodiments, a system is provided, the system comprising: a hardware processor programmed to: receive displacement data of tissue in vivo; provide the displacement data to a trained ANN that was trained using noisy input datasets as training data, and derivative datasets corresponding to the noisy input datasets to evaluate performance during training, such that the trained ANN provides an output dataset corresponding to an analytical solution to a derivative of a function represented in an unlabeled input dataset thereby transforming the unlabeled input dataset into its derivative; receive, from the trained ANN, an output dataset indicative of a derivative of the displacement data; and estimate stiffness of the tissue based on the derivative. |
| FILED | Thursday, January 28, 2021 |
| APPL NO | 17/796431 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) Original (OR) Class G01R 33/56358 (20130101) Computer Systems Based on Specific Computational Models G06N 3/0464 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12020440 | Prince et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Jerry L. Prince (Baltimore, Maryland); Aaron Carass (Towson, Maryland); Yihao Liu (Towson, Maryland) |
| ABSTRACT | A device receives a two-dimensional (2-D) image that depicts a cross-sectional view of a retina that includes a macula comprised of layers and boundaries used to segment the layers. The device converts the 2-D image to a standardized format, determines features for voxels included in the 2-D image, and generates, by using a data model to process the features, probability maps that indicate likelihoods of the voxels being in positions within particular boundaries. The device analyzes the probability maps to determine an initial set of boundary positions and to generate directional vectors that point in directions based on values included in the set of probability maps, determines a final set of boundary positions by performing a layer boundary evolution technique using the directional vectors to refine the initial set of boundary positions, and provides data that identifies the final set of boundary positions for display via an interface. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 17/310330 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/143 (20170101) Original (OR) Class G06T 2207/10101 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20182 (20130101) G06T 2207/30041 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12020494 | Bharti et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Kapil Bharti (Potomac, Maryland); Nathan A. Hotaling (Washington, District of Columbia); Nicholas J. Schaub (Gaithersburg, Maryland); Carl G. Simon (Gaithersburg, Maryland) |
| ABSTRACT | A method is provided for non-invasively predicting characteristics of one or more cells and cell derivatives. The method includes training a machine learning model using at least one of a plurality of training cell images representing a plurality of cells and data identifying characteristics for the plurality of cells. The method further includes receiving at least one test cell image representing at least one test cell being evaluated, the at least one test cell image being acquired noninvasively and based on absorbance as an absolute measure of light, and providing the at least one test cell image to the trained machine learning model. Using machine learning based on the trained machine learning model, characteristics of the at least one test cell are predicted. The method further includes generating, by the trained machine learning model, release criteria for clinical preparations of cells based on the predicted characteristics of the at least one test cell. |
| FILED | Wednesday, November 09, 2022 |
| APPL NO | 17/983963 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/2148 (20230101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10056 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 20/69 (20220101) Original (OR) Class G06V 20/695 (20220101) G06V 20/698 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12016682 | Ferguson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University Of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Brian Scott Ferguson (Goleta, California); Hyongsok Tom Soh (Santa Barbara, California); David A. Hoggarth (Toronto, Canada) |
| ABSTRACT | The present disclosure provides devices, methods and systems for analyte detection and/or monitoring, e.g., the continuous and/or semi-continuous monitoring of in-vivo analyte concentrations in real time. Generally, the devices, methods and systems of the present disclosure make use of signaling probes; methods or devices for reducing interferent-based fouling of the signaling probes, non-specific binding to the signaling probes and/or occlusion of a sensor surface; and methods and/or devices for providing an adjusted signal based on a detected signal from the signaling probes. Compositions including conformation switching signaling probes are also provided. |
| FILED | Wednesday, January 29, 2014 |
| APPL NO | 14/768134 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1473 (20130101) A61B 5/4839 (20130101) A61B 5/14525 (20130101) Original (OR) Class A61B 5/14546 (20130101) A61B 5/14735 (20130101) A61B 5/150992 (20130101) A61B 2503/40 (20130101) A61B 2503/42 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2320/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 2525/205 (20130101) C12Q 2565/629 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016788 | Jung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ranu Jung (Coral Gables, Florida); Shah Vikram Jung (Freemont, California); Brundavani Srimattirumalaparle (Glendale, Arizona) |
| ASSIGNEE(S) | Advensys, LLC (Fayetteville, Arkansas) |
| INVENTOR(S) | Ranu Jung (Coral Gables, Florida); Shah Vikram Jung (Freemont, California); Brundavani Srimattirumalaparle (Glendale, Arizona) |
| ABSTRACT | A neuromorphic controlled powered orthotic and prosthetic system and device including a custom or universal fit fixed-ankle orthosis, to stabilize or immobilize an injured lower limb or act as an ankle prosthesis, and an actuated or powered articulated false-foot connected to the fixed-ankle orthosis or the prosthesis to form an actuated articulated false-foot orthosis. Associated with or mounted on the actuated articulated false-foot, or in or on the body, are sensors for sensing the intent of the subject to move, and the movement range of the articulating false-foot or AAFO and an environmental perturbation. An actuator is used to drive the articulated false-foot orthosis. The system and device further include a controller having an electronic circuit with a biomimetic design based on knowledge of connectivity of neurons within the spinal cord of a primitive vertebrate. The system and device include an electronic circuit made from analog very large scale integrated components and discrete electronic components capable of autonomously generating cyclic voltage output. An integral power supply serves the portable controller and AAFO. |
| FILED | Wednesday, July 02, 2014 |
| APPL NO | 14/322326 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/66 (20130101) A61F 2/72 (20130101) Original (OR) Class A61F 2002/607 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) A61H 2003/005 (20130101) A61H 2003/007 (20130101) A61H 2201/0103 (20130101) A61H 2201/1246 (20130101) A61H 2201/5007 (20130101) A61H 2201/5069 (20130101) A61H 2230/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016948 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Joseph Wang (San Diego, California); Liangfang Zhang (San Diego, California) |
| ABSTRACT | Disclosed are nano/micromotor devices, systems, and methods for providing payloads in the gastrointestinal system. In one aspect, a micromotor for a gastrointestinal tract includes a micromotor body including a one or more material layers to provide a structure that surrounds a hollow interior region and has an opening to an exterior of the micromotor body; one or more particles including a biocompatible metal element, the one or more particles contained in the interior region of the micromotor body; a coating coupled to the structure of the micromotor body; and a payload material, in which the micromotor is structured to move in a fluid of a gastrointestinal system based on a reaction between the one or more particles and a constituent or a condition of the fluid, such that the reaction generates bubbles that accelerate out of the opening of the micromotor body to propel the micromotor in the fluid. |
| FILED | Friday, January 05, 2018 |
| APPL NO | 16/475894 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4222 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0007 (20130101) Original (OR) Class A61K 9/0053 (20130101) A61K 9/204 (20130101) A61K 9/205 (20130101) A61K 9/501 (20130101) A61K 9/2009 (20130101) A61K 9/2027 (20130101) A61K 9/2086 (20130101) A61K 9/4808 (20130101) A61K 9/4866 (20130101) A61K 9/5026 (20130101) A61K 9/5031 (20130101) A61K 9/5036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017195 | Qing et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Quan Qing (Chandler, Arizona); Ching-wei Tsao (Tempe, Arizona); Peiming Zhang (Gilbert, Arizona) |
| ABSTRACT | The present disclosure provides an apparatus for synthesizing a biopolymer, a method for preparing an apparatus for synthesizing a biopolymer, and a method of synthesizing a biopolymer. The apparatus comprises (a) a substrate comprising atop surface and a plurality of wells, wherein each of the plurality of wells comprises a first electrode disposed on the bottom of the well and a linker attached to the sides of the well; and (b) a fluidic chamber system disposed on the top surface of the substrate. |
| FILED | Monday, July 01, 2019 |
| APPL NO | 17/257816 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 19/0093 (20130101) Original (OR) Class B01J 2219/00317 (20130101) B01J 2219/00529 (20130101) B01J 2219/00596 (20130101) B01J 2219/00653 (20130101) B01J 2219/00659 (20130101) B01J 2219/00713 (20130101) B01J 2219/00722 (20130101) B01J 2219/00822 (20130101) B01J 2219/00853 (20130101) B01J 2219/00855 (20130101) Peptides C07K 1/045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017229 | Glezer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Meso Scale Technologies, LLC. (Rockville, Maryland) |
| ASSIGNEE(S) | MESO SCALE TECHNOLOGIES, LLC. (Rockville, Maryland) |
| INVENTOR(S) | Eli N. Glezer (Del Mar, California); Bandele Jeffrey-Coker (Darnestown, Maryland); Kenneth Page (Germantown, Maryland); Sandor Kovacs (Middletown, Delaware); Sudeep Kumar (Gaithersburg, Maryland); Kristian Roth (Germantown, Maryland) |
| ABSTRACT | Assay cartridges are described that have a plurality of chambers and a fluidic network that includes fluidic conduits and a multi-port valve designed to selectively connect the valve inlet and one valve outlet through a fluidic connector in the valve as the remaining valve outlets are sealed. |
| FILED | Friday, October 01, 2021 |
| APPL NO | 17/492207 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 3/567 (20130101) Original (OR) Class B01L 3/5085 (20130101) B01L 3/502738 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) B01L 2300/0867 (20130101) B01L 2300/0874 (20130101) B01L 2400/0487 (20130101) B01L 2400/0622 (20130101) B01L 2400/0644 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 11/0743 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/2575 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017276 | Hildreth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado School of Mines (Golden, Colorado) |
| ASSIGNEE(S) | Colorado School of Mines (Golden, Colorado) |
| INVENTOR(S) | Owen Hildreth (Lakewood, Colorado); Meredith Heilig (Golden, Colorado); Sanaz Yazdanparast (Golden, Colorado); Subbarao Raikar (Golden, Colorado) |
| ABSTRACT | A method is provided to remove a selective amount of material from a metal component fabricated by additive manufacturing in a self-terminating manner. The method can be used to remove support structures and trapped powder from a metal component as well as to smooth surfaces of a 3D printed metal component. In some embodiments, selected surfaces of the metal component are treated to make the selected surfaces at least one of mechanically and chemically unstable. The unstable portion of the metal support can then be removed chemically, electrochemically, or through vapor-phase etching. The method can be used for processing any fluid or vapor-accessible regions and surfaces of a 3D printed metal component. |
| FILED | Thursday, March 17, 2022 |
| APPL NO | 17/697814 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/40 (20210101) B22F 10/62 (20210101) Original (OR) Class B22F 10/68 (20210101) B22F 2301/10 (20130101) B22F 2301/15 (20130101) B22F 2301/052 (20130101) B22F 2301/205 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/20 (20200101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/12 (20130101) C23F 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017750 | Walter |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Arlington, Virginia) |
| INVENTOR(S) | Matthew W. Walter (Troy, Missouri) |
| ABSTRACT | Pyrotechnic devices and firing mechanisms for aircraft canopy jettison are disclosed herein. An example firing mechanism includes a housing defining a first bore, a second bore, and a channel between the first bore and the second bore, a primary charge disposed in the second bore, a closure disc between the second bore and the channel, and a firing pin assembly disposed in the first bore. The firing pin assembly includes a percussion primer and a firing pin piston including a piston body, a firing pin extending from the piston body, and a piercing pin extending from the piston body. In response to a firing signal, the firing pin piston is moved toward the primary charge such that the piercing pin punctures the closure disc and the firing pin engages the percussion primer to ignite the primary charge. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860785 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/32 (20130101) Original (OR) Class B64C 1/1476 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017920 | Vecchio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kenneth Vecchio (San Diego, California); Tyler Harrington (New York, New York) |
| ABSTRACT | A multicomponent carbide has at least five transition metals, and a valence electron concentration (VEC) is greater 8.80 electrons. Preferred off-equiatomic multicomponent carbides have five transition metals and a VEC of more than 8.80. Preferred equiatomic multicomponent carbides have five transition metals and a VEC of 9.00 or greater. The valence electron configuration is important for its relationship to the mechanical properties of carbides. Since carbon forms four bonds, when there are more than four valence electrons available from the metals, there are excess electrons in the system. This increases metallic character of bonding and therefore allows for more ductility and higher toughness. |
| FILED | Tuesday, November 10, 2020 |
| APPL NO | 17/094337 |
| ART UNIT | 1738 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/907 (20170801) Original (OR) Class Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/5611 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017972 | Tan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | The Government of the United States of America as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Loon-Seng Tan (Centerville, Ohio); Zhenning Yu (Beavercreek, Ohio) |
| ABSTRACT | A family of low-molecular-weight, main-chain thermotropic liquid-crystalline polyimides (TLC-PI) that are crosslinkable is disclosed. These all-aromatic TLC-PI are derived from (i) wholly aromatic and flexible diamine monomers, in which the linkage between the two aniline-ends contains a relatively high heat-tolerant but flexible chain constituted by two or more units of 1,4-phenoxy or 1,3-phenoxy or in combinations of both. Processes of making and using such all-aromatic TLC-PI is also provided. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/299375 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 213/06 (20130101) C07C 217/90 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/1071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018193 | Ma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Biwu Ma (Tallahassee, Florida); Chenkun Zhou (Tallahassee, Florida); Haoran Lin (Tallahassee, Florida); Yu Tian (Tallahassee, Florida) |
| ABSTRACT | Bulk assemblies are provided, which may have desirable photoluminescence quantum efficiencies. The bulk assemblies may include two or more metal halides, and a wide band gap organic network. The wide band gap organic network may include organic cations. The metal halides may be disposed in the wide band gap organic network. Light emitting composite materials also are provided. |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/180601 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class C09K 11/664 (20130101) C09K 11/7428 (20130101) C09K 11/7734 (20130101) C09K 2211/1007 (20130101) C09K 2211/1011 (20130101) C09K 2211/1014 (20130101) C09K 2211/1018 (20130101) C09K 2211/1022 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/20 (20130101) H05B 33/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018252 | Johnston et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Stephen Albert Johnston (Tempe, Arizona); Luhui Shen (Tempe, Arizona) |
| ABSTRACT | Provided herein, are methods of identifying neoantigens for treating and preventing cancer. Also disclosed are methods and compositions for administering identified neoantigens for the treatment and prevention of cancer. |
| FILED | Friday, April 01, 2022 |
| APPL NO | 17/711849 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/16 (20130101) A61K 39/0011 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1062 (20130101) Original (OR) Class C12N 15/1093 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 33/57488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018315 | Irvine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Imperial College Innovations Limited (London, United Kingdom) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Imperial College Innovations Limited (London, United Kingdom) |
| INVENTOR(S) | Darrell J. Irvine (Arlington, Massachusetts); Jason Y. H. Chang (Cambridge, Massachusetts); Sylvain Ladame (Tring, United Kingdom); Dana Al Sulaiman (London, United Kingdom) |
| ABSTRACT | The present disclosure relates to a device, comprising a base and a plurality of microneedles attached to the base, wherein each microneedle has an outer surface; the outer surface of at least one microneedle being coated with a composition comprising at least one polymer and least one Peptide Nucleic Acid (PNA). The present disclosure additionally relates to a method of detecting an analyte in interstitial fluid (ISF), comprising contacting the device to a subject, for example, to human skin. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/887649 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/36 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6823 (20130101) C12Q 2565/629 (20130101) C12Q 2565/1025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018394 | Schaedler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
| INVENTOR(S) | Tobias A. Schaedler (Oak Park, California); John H. Martin (Ventura, California) |
| ABSTRACT | A thin-walled metal part, and a method to fabricate such a part out of various alloys. A plurality of layers are formed, each of the layers being formed on a polymer template or on a previously formed layer. A homogenizing heat treatment is used to cause chemical elements in the layers to interdiffuse, to form a single continuous layer with a substantially uniform alloy composition. |
| FILED | Thursday, April 13, 2023 |
| APPL NO | 18/300105 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/12 (20130101) B32B 15/01 (20130101) B32B 15/043 (20130101) Alloys C22C 19/002 (20130101) C22C 19/03 (20130101) C22C 19/058 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/10 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 10/38 (20130101) C23C 10/48 (20130101) C23C 28/023 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 1/02 (20130101) Original (OR) Class C25D 3/12 (20130101) C25D 3/56 (20130101) Jet-propulsion Plants F02K 9/97 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018443 | Zavattieri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Pablo Daniel Zavattieri (West Lafayette, Indiana); Scott M Hartford (South Bend, Indiana); Kristiaan William Hector (Shelby Township, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pablo Daniel Zavattieri (West Lafayette, Indiana); Scott M Hartford (South Bend, Indiana); Kristiaan William Hector (Shelby Township, Michigan) |
| ABSTRACT | A flexible runway mat system, including a plurality of base platforms, each respective base platform having a first pattern of phase transforming columns and voids extending from a respective flat member, and a plurality of plane-engaging runway platforms, each respective plane-engaging runway platform having a second, reversed pattern of phase transforming columns and voids extending from a respective flat member such that each respective plane-engaging runway platform is lockingly engagable to a respective base platform to yield a landing segment with parallel top and bottom flat members. Each respective phase transforming column is further comprised of a plurality of stacked operationally connected phase transforming cellular members. Each respective phase transforming cellular member can shift from a first stable configuration to a second stable configuration in response to an applied load. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/245154 |
| ART UNIT | 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/12 (20130101) B32B 15/012 (20130101) B32B 2307/54 (20130101) B32B 2307/56 (20130101) B32B 2471/04 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/36 (20130101) Construction Of, or Surfaces For, Roads, Sports Grounds, or the Like; Machines or Auxiliary Tools for Construction or Repair E01C 5/223 (20130101) E01C 9/00 (20130101) Original (OR) Class E01C 9/083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018613 | Bohan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Brian Bohan (Dayton, Ohio); Marc Polanka (Huber Heights, Ohio); Bennett Staton (Beavercreek, Ohio) |
| ABSTRACT | A disk engine and system configured to provide high power at a reduced axial length is disclosed herein. The disk engine includes a radial compressor, a compressor discharge manifold positioned circumferentially about compressor, a combustion chamber positioned within the discharge manifold and a radial turbine positioned radially inward of the combustion chamber. |
| FILED | Wednesday, June 22, 2022 |
| APPL NO | 17/846633 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/08 (20130101) Original (OR) Class F02C 3/085 (20130101) F02C 7/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018621 | Heeter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Robert W. Heeter (Indianapolis, Indiana); Daniel E. Molnar, Jr. (Indianapolis, Indiana); Michael S. Krautheim (Indianapolis, Indiana) |
| ABSTRACT | A fan case assembly adapted for use with a gas turbine engine includes a case at extends circumferentially at least partway about an axis of the gas turbine engine and a plurality of vanes. The case is formed to define a channel that extends circumferentially at least partway about the axis. The plurality of vanes are arranged in the channel and spaced apart circumferentially about the axis. |
| FILED | Wednesday, August 16, 2023 |
| APPL NO | 18/234657 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/141 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/22 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/06 (20130101) Non-positive-displacement Pumps F04D 29/542 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/36 (20130101) F05D 2240/12 (20130101) F05D 2240/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018661 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Xi Chen (New York, New York); Rein Ulijn (New York, New York); Roxana Piotrowska (New York, New York) |
| ABSTRACT | A thin film that has a flexible polymer layer and a peptide layer. The peptide layer is disposed on the flexible polymer layer and has a peptide selected from HYF, DYF and YFD. The thin film reversibly curves with changes in humidity. |
| FILED | Monday, January 04, 2021 |
| APPL NO | 17/140639 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Peptides C07K 5/0812 (20130101) C07K 5/0819 (20130101) C07K 5/0821 (20130101) Compositions of Macromolecular Compounds C08L 7/00 (20130101) C08L 21/02 (20130101) C08L 67/02 (20130101) C08L 69/00 (20130101) C08L 79/08 (20130101) C08L 83/04 (20130101) C08L 2203/16 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018922 | Chamberlain et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Department of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Keith Chamberlain (Waldorf, Maryland); Lee Foltz (Indian Head, Maryland); Angel Diaz (Waldorf, Maryland) |
| ABSTRACT | A cap for an explosive water charge may be fixed to a collapsible water bottle by threading internal threads of the cap onto external threads of the water bottle. The cap also may be fixed to a water bottle by engaging a lip on the water bottle with lip grabbers on the cap. The cap is configured to hold a blasting cap and two different sizes of tubes of energetic material. |
| FILED | Friday, December 16, 2016 |
| APPL NO | 15/530249 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/26 (20130101) F42B 33/062 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019013 | Bruno et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | Government of the United States as Represented by the Secretary of the Army (, None) |
| INVENTOR(S) | Ferdinando F Bruno (Reading, Massachusetts); Manuele Bernabei (Rome, Italy); LTC Andrea Chiappa (Rome, Italy); David Ziegler (Clinton, Massachusetts); Nicole F Farhadi (Plymouth, Massachusetts) |
| ABSTRACT | The disclosed subject matter relates to a method of treating of asbestos or asbestos-containing material, comprising applying to the asbestos or asbestos-containing material a composition including a treatment compound comprising at least one of hexafluoro titanium di-ammonium, potassium hexafluoro zirconate. ammonium hexafluoro phosphate. ammonium hexafluoro stannate, ammonium hexafluoro germanate, ammonium tetrafluoro borate or ammonium heptafluoro tantalite; and a fluorine scavenger compound. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/389411 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 2101/41 (20130101) Disposal of Solid Waste B09B 3/0066 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2273 (20130101) G01N 21/35 (20130101) Original (OR) Class G01N 2021/3595 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019130 | Englund |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | Chemical-shift nuclear magnetic resonance (NMR) spectroscopy involves measuring the effects of chemical bonds in a sample on the resonance frequencies of nuclear spins in the sample. Applying a magnetic field to the sample causes the sample nuclei to emit alternating current magnetic fields that can be detected with color centers, which can act as very sensitive magnetometers. Cryogenically cooling the sample increases the sample's polarization, which in turn enhances the NMR signal strength, making it possible to detect net nuclear spins for very small samples. Flash-heating the sample or subjecting it to a magic-angle-spinning magnetic field (instead of a static magnetic field) eliminates built-in magnetic field inhomogeneities, improving measurement sensitivity without degrading the sample polarization. Tens to hundreds of small, cryogenically cooled sample chambers can be integrated in a semiconductor substrate interlaced with waveguides that contain color centers for optically detected magnetic resonance measurements of the samples' chemical-shift NMR frequencies. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/465895 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/31 (20130101) G01R 33/46 (20130101) Original (OR) Class G01R 33/282 (20130101) G01R 33/323 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019173 | Kassas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Zak M. Kassas (Irvine, California); Mahdi Maaref (Irvine, California); Joe Khalife (Costa Mesa, California) |
| ABSTRACT | A vehicular simultaneous localization and mapping may fuse lidar data and pseudoranges extracted from ambient cellular LTE towers. An ICP algorithm may be used to extract odometry measurements from successive lidar scans. A robust and computationally efficient feature extraction method may be used to detect edge lines and feature points from the lidars point cloud. Then, a point registration technique using a maximum likelihood approach allows the estimation of the covariance of the odometry error, which is used in EKF propagation. The proposed approach consists of a mapping mode when GNSS signals are available and subsequently a SLAM mode when GNSS signals become unavailable. The cellular transmitters states, namely position and clock bias and clock drift, are continuously estimated in both modes. Simulation and experimental results validate the accuracy of these systems and methods, and provides lane-level localization without GNSS signals. |
| FILED | Friday, August 23, 2019 |
| APPL NO | 17/270763 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/188 (20200801) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/89 (20130101) G01S 19/485 (20200501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019353 | Puckett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| INVENTOR(S) | Matthew W. Puckett (Phoenix, Arizona); Chad Hoyt (Plymouth, Minnesota); Karl Nelson (Plymouth, Minnesota); Jianfeng Wu (Phoenix, Arizona) |
| ABSTRACT | An optical frequency comb generation system includes an optical waveguide portion having a uniform width, a first chirped Bragg grating disposed at one end of the optical waveguide portion and a second chirped Bragg grating disposed at the other end of the optical waveguide portion. The first chirped Bragg grating includes at least a first periodic variation having a first refractive index and a second periodic variation having a second refractive index. The second chirped Bragg grating includes the at least first and second periodic variations. A first cavity associated with a first resonant frequency extends between the first periodic variation of the first chirped Bragg grating and the first periodic variation of the second chirped Bragg grating. A second cavity associated with a second resonant frequency extends between the second periodic variation of the first chirped Bragg grating and the second periodic variation of the second chirped Bragg grating. |
| FILED | Wednesday, October 12, 2022 |
| APPL NO | 18/045936 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) Original (OR) Class G02F 1/3542 (20210101) G02F 2201/307 (20130101) G02F 2203/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019412 | Granger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Richard Granger (Hanover, New Hampshire); Elijah Floyd William Bowen (Hanover, New Hampshire); Antonio Rodriguez (Hanover, New Hampshire); Andrew Felch (Hanover, New Hampshire) |
| ABSTRACT | An autonomous module for processing stored data includes a multithreaded processor core (MPC) and a plurality of autonomous memories. Each of the plurality of autonomous memories has a memory bank, a data operator (DO) configured to implement a plurality of selectable memory behaviors, an autonomous memory operator (AMO) configured to implement a state machine to control the memory bank independently of the MPC, and at least one memory input/output (IO) port communicatively coupled with the memory bank, the AMO, and the DO. The at least one memory IO port is configured to receive a read instruction from the AMO, retrieve data from the memory bank, and send the data to the DO. The DO is configured to implement one of the plurality of selectable memory behaviors to update the data and send the updated data to the AMO via the at least one memory IO port. |
| FILED | Monday, June 26, 2023 |
| APPL NO | 18/214303 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/027 (20130101) Original (OR) Class Electric Digital Data Processing G06F 7/50 (20130101) G06F 7/523 (20130101) G06F 17/16 (20130101) G06F 17/141 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/454 (20220101) G06V 10/764 (20220101) G06V 10/955 (20220101) G06V 10/7635 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019736 | DeHon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Andre Maurice DeHon (Philadelphia, Pennsylvania); Nicholas Edward Roessler (Philadelphia, Pennsylvania) |
| ABSTRACT | Methods, systems, and computer readable media for using metadata tag compression. A method occurs at a metadata processing system for enforcing security policies in a processor architecture. The method comprises: receiving, at the metadata processing system, a short tag associated with a word in memory; translating the short tag, using a tag map, into a long tag, wherein the short tag indicates a location of the long tag relative to an offset in the tag map and wherein the long tag indicates a memory location containing metadata associated with the word or an instruction; obtaining the metadata from the memory location; and determining, using the metadata, whether the word or the instruction violates a security policy. |
| FILED | Monday, March 01, 2021 |
| APPL NO | 17/188547 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/54 (20130101) Original (OR) Class G06F 21/79 (20130101) G06F 21/554 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019887 | Reese et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Idaho Scientific LLC (Boise, Idaho) |
| ASSIGNEE(S) | IDAHO SCIENTIFIC LLC (Boise, Idaho) |
| INVENTOR(S) | Dale Weston Reese (Boise, Idaho); Matthew Ryan Waltz (Boise, Idaho); Jay Takeji Hirata (Meridian, Idaho); Andrew James Weiler (Nampa, Idaho); Nathan Charles Chrisman (Nampa, Idaho); Claude Harmon Garrett, V (Meridian, Idaho) |
| ABSTRACT | Hardware enforced CPU core protection by identification of digital blocks as instructions or data. A method includes, at a memory controller shim, receiving, from a CPU core, a memory read request. The memory read request comprises an address for a block. The block at the address is requested from a memory. The block is received from the memory. At least one of a decryption key or an authentication key is accessed. At least one of a decryption transformation or an authentication transformation is performed on the block using the decryption key or the authentication key. When the decryption transformation or authentication transformation is deemed valid, a plain text version of the block is returned to the CPU core for consumption. When the decryption transformation or authentication transformation is deemed invalid, the CPU core is prevented from consuming the plain text version of the block. |
| FILED | Tuesday, August 16, 2022 |
| APPL NO | 17/889010 |
| ART UNIT | 2133 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/062 (20130101) G06F 3/064 (20130101) Original (OR) Class G06F 3/0658 (20130101) G06F 3/0679 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019920 | Brewer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas) |
| ABSTRACT | A memory controller circuit is disclosed which is coupleable to a first memory circuit, such as DRAM, and includes: a first memory control circuit to read from or write to the first memory circuit; a second memory circuit, such as SRAM; a second memory control circuit adapted to read from the second memory circuit in response to a read request when the requested data is stored in the second memory circuit, and otherwise to transfer the read request to the first memory control circuit; predetermined atomic operations circuitry; and programmable atomic operations circuitry adapted to perform at least one programmable atomic operation. The second memory control circuit also transfers a received programmable atomic operation request to the programmable atomic operations circuitry and sets a hazard bit for a cache line of the second memory circuit. |
| FILED | Sunday, October 02, 2022 |
| APPL NO | 17/958404 |
| ART UNIT | 2138 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0659 (20130101) Original (OR) Class G06F 3/0683 (20130101) G06F 12/0875 (20130101) G06F 2212/452 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019967 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Nvidia Corporation (Santa Clara, California) |
| ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
| INVENTOR(S) | Haoxing Ren (Austin, Texas); Matthew Fojtik (Chapel Hill, North Carolina) |
| ABSTRACT | The disclosure provides a general solution for determining connections between terminals of various types of circuits using machine learning (ML). A ML method that uses reinforcement learning (RL), such as deep RL, to determine and optimize routing of circuit connections using a game process is provided. In one example a method of determining routing connection includes: (1) receiving a circuit design having known terminal groups, (2) establishing terminal positions for the terminal groups in a routing environment, and (3) determining, by the RL agent, routes of nets between the known terminal groups employing a model that is independent of a number of the nets of the circuit. A method of creating a model for routing nets using RL, a method of employing a game for training a RL agent to determine routing connections, and a RL agent for routing connections of a circuit are also disclosed. |
| FILED | Wednesday, April 14, 2021 |
| APPL NO | 17/230016 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 30/394 (20200101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019981 | Surdeanu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Mihai Surdeanu (Tucson, Arizona); Marco A. Valenzuela Escarcega (Tucson, Arizona); Gustave Hahn-Powell (Tucson, Arizona); Dane Bell (Tucson, Arizona); Thomas Hicks (Tucson, Arizona); Enrique Noriega (Tucson, Arizona); Clayton Morrison (Tucson, Arizona); Rebecca Sharp (Tucson, Arizona); Robert Ionut Vacareanu (Botosani, Romania); George Barbosa (Tucson, Arizona) |
| ABSTRACT | A machine reading system is described herein that includes a framework in which grammar rules can be developed using a concise language that combines syntax and semantics. The resulting technology thus reduces the development time for new grammars in a new domain. An enormous amount of information appears in the form of natural language across millions of academic papers and other literature sources. For example, in the biological domain, there is a tremendous ongoing effort to extract individual chemical interactions from these texts, but these interactions are only isolated fragments of larger causal mechanisms such as protein signaling pathways. The proposed rule-based event extraction framework can model underlying syntactic representations of events in order to extract signaling pathway fragments. Though application to the biomedical domain is herein described, the framework is domain-independent and is expressive enough to capture most complex events annotated by domain experts. |
| FILED | Thursday, June 10, 2021 |
| APPL NO | 17/344774 |
| ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0482 (20130101) G06F 16/245 (20190101) G06F 40/30 (20200101) G06F 40/169 (20200101) G06F 40/211 (20200101) Original (OR) Class G06F 40/253 (20200101) G06F 40/284 (20200101) G06F 40/295 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12020062 | Brewer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Tony Brewer (Plano, Texas) |
| ABSTRACT | Chiplet systems may include a memory controller that has programmable atomic units that execute programmable atomic transactions. These instructions are stored in one or more memory partitions of memory in the programmable atomic unit. Since the programmable atomic unit executes programmable atomic transactions that are customized for various processes, and since the programmable atomic unit is a physical resource shared by multiple processes, the processes need a way of both loading the programmable atomic unit memory with instructions and a method of calling those instructions. Disclosed are methods, systems, and devices for registering, calling, and virtualizing programmable atomic transactions. |
| FILED | Tuesday, October 20, 2020 |
| APPL NO | 17/074811 |
| ART UNIT | 2627 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 9/467 (20130101) Original (OR) Class G06F 12/0815 (20130101) G06F 12/0875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12020828 | Saffman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Mark Saffman (Madison, Wisconsin) |
| ABSTRACT | A system and method for controlling particles using projected light are provided. In some aspects, the method includes generating a beam of light using an optical source, and directing the beam of light to a beam filter comprising a first mask, a first lens, a second mask, and a second lens. The method also includes forming an optical pattern using the beam filter, and projecting the optical pattern on a plurality of particles to control their locations in space. |
| FILED | Friday, January 03, 2020 |
| APPL NO | 17/420542 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12020985 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Travis J. Anderson (Alexandria, Virginia); Marko J. Tadjer (Vienna, Virginia); Karl D. Hobart (Alexandria, Virginia) |
| ABSTRACT | Methods for obtaining a free-standing thick (>5 μm) epitaxial material layer or heterostructure stack and for transferring the thick epitaxial layer or stack to an arbitrary substrate. A thick epitaxial layer or heterostructure stack is formed on an engineered substrate, with a sacrificial layer disposed between the epitaxial layer and the engineered substrate. When the sacrificial layer is removed, the epitaxial layer becomes a thick freestanding layer that can be transferred to an arbitrary substrate, with the remaining engineered substrate being reusable for subsequent material layer growth. In an exemplary case, the material layer is a GaN layer and can be selectively bonded to an arbitrary substrate to selectively produce a Ga-polar or an N-polar GaN layer. |
| FILED | Monday, May 24, 2021 |
| APPL NO | 17/327816 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/02 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 43/006 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/406 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0242 (20130101) H01L 21/0254 (20130101) H01L 21/02568 (20130101) H01L 21/4807 (20130101) H01L 21/7813 (20130101) Original (OR) Class H01L 23/3732 (20130101) H01L 29/24 (20130101) H01L 29/872 (20130101) H01L 29/2003 (20130101) H01L 29/7786 (20130101) Technical Subjects Covered by Former US Classification Y10T 156/1168 (20150115) Y10T 156/1911 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021062 | Placke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Michael G. Placke (McKinney, Texas); Tony Brewer (Plano, Texas) |
| ABSTRACT | A chiplet-based system comprises a substrate including conductive interconnect and multiple chiplets arranged on the interposer and interconnected using the conductive interconnect of the substrate. A chiplet includes multiple columns of multiple input-output (I/O) channels and the I/O channels are connected to a block of I/O pads and each side of the chiplet includes multiple blocks of the I/O pads. The multiple blocks of I/O pads on the side of the chiplet are arranged symmetrically relative to a centerline of the chiplet and each block of I/O pads on the side of the chiplet is at a common distance from any adjacent block of I/O pads on the side. |
| FILED | Tuesday, October 20, 2020 |
| APPL NO | 17/075117 |
| ART UNIT | 2897 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 24/16 (20130101) H01L 25/0655 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021201 | Ergen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Onur Ergen (Berkeley, California); Alexander K. Zettl (Kensington, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to Li-ion batteries. In one aspect an electrolyte structure for use in a battery comprises an electrolyte and an interconnected boron nitride structure disposed in the electrolyte. |
| FILED | Tuesday, January 11, 2022 |
| APPL NO | 17/573488 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/056 (20130101) H01M 10/0525 (20130101) H01M 10/4235 (20130101) Original (OR) Class H01M 2300/0025 (20130101) H01M 2300/0045 (20130101) H01M 2300/0071 (20130101) H01M 2300/0085 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021345 | Boyd et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vector Atomic, Inc. (Pleasanton, California) |
| ASSIGNEE(S) | Vector Atomic, Inc. (Pleasanton, California) |
| INVENTOR(S) | Martin Machai Boyd (Pleasanton, California); Arman Cingoz (Pleasanton, California); Abijith Sudarsan Kowligy (Livermore, California); William David Lunden (Dublin, California); Jonathan David Roslund (Pleasanton, California) |
| ABSTRACT | Embodiments herein describe peak detection techniques for selecting an absorption line to lock a spectroscopy laser in a frequency reference (e.g., an atomic clock). In one embodiment, an atomic reference is used which has many absorption lines within a relatively small frequency range (e.g., within a gain profile of the spectroscopy laser). The peak detection techniques can evaluate which of these lines a laser can be locked to. For example, the peak detection algorithm can define a preferred absorption line. But if for some reason the spectroscopy laser cannot be locked to the preferred absorption line, the peak detection technique has at least one backup absorption line. By having a set of candidate absorption lines, the peak detection algorithm can identify a suitable absorption line for lasers with different gain regions, or as gain regions change. |
| FILED | Friday, January 12, 2024 |
| APPL NO | 18/411435 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Time-interval Measuring G04F 5/14 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/1109 (20130101) Original (OR) Class H01S 3/1303 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021507 | Safavi-Naeini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Amir H. Safavi-Naeini (Palo Alto, California); Marek Pechal (Zurich, Switzerland); Patricio Arrangoiz-Arriola (Clarksville, Maryland); Edward Alexander Wollack (Clarksville, Maryland) |
| ABSTRACT | A coupled storage qubit nanomechanical resonator in a processing qubit superconducting circuit is provided that includes a phononic crystal resonator (PCR) film disposed on a substrate, where the PCR film includes a defect mode in a bandgap of the PCR film where a storage qubit is encoded, a pair of electrodes generate voltages within the PCR film, where the defect is dimensioned to support a unique electrical potential generated by a local mechanical phonon mode of the PCR film, where a unique resonance frequency that is dependent on the defect dimensions is output from the PCR film, a coupling capacitor that is coupled to the PCR film, where the coupling capacitor is disposed to receive the output unique resonance frequency, and a processing qubit, where the processing qubit is capacitively coupled to the PCR film by the coupling capacitor, where the storage qubits are connected to the processing qubits. |
| FILED | Monday, August 26, 2019 |
| APPL NO | 16/551004 |
| ART UNIT | 2124 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) G06N 10/40 (20220101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021829 | Rye et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Eric Charles Rye (Severna Park, Maryland); Robert Edward Beverly, IV (Carmel, California) |
| ABSTRACT | The invention relates to discovering and clustering Internet protocol addresses. For example, the invention can include discovering an IPv6 address of an Internet-facing device on a network, where the IPv6 address is associated with a wide area network (WAN) media access control (MAC) address and a WiFi basic service set identifier (BSSID), identifying an associated BSSID in WiFi geolocation databases based on the WAN and WiFi BSSID, and geolocating the Internet-facing device by retrieving a location record in the WiFi geolocation databases for the associated BSSID. |
| FILED | Friday, October 14, 2022 |
| APPL NO | 17/966537 |
| ART UNIT | 2443 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 61/5007 (20220501) Original (OR) Class H04L 2101/659 (20220501) Wireless Communication Networks H04W 8/26 (20130101) H04W 84/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12022748 | Tahir-Kheli |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Jamil Tahir-Kheli (Pasadena, California) |
| ABSTRACT | A superconducting composition of matter including overlapping first and second regions. The regions comprise unit cells of a solid, the first region comprises an electrical insulator or semiconductor, and the second region comprises a metallic electrical conductor. The second region extends through the solid and a subset of said second region comprise surface metal unit cells that are adjacent to at least one unit cell from the first region. The ratio of the number of said surface metal unit cells to the total number of unit cells in the second region being at least 20 percent. |
| FILED | Wednesday, February 01, 2023 |
| APPL NO | 18/162817 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/45 (20130101) C04B 35/4504 (20130101) C04B 35/4508 (20130101) C04B 35/62645 (20130101) C04B 2235/327 (20130101) C04B 2235/422 (20130101) C04B 2235/3206 (20130101) C04B 2235/3208 (20130101) C04B 2235/3213 (20130101) C04B 2235/3215 (20130101) C04B 2235/3222 (20130101) C04B 2235/3224 (20130101) C04B 2235/3225 (20130101) C04B 2235/3232 (20130101) C04B 2235/3241 (20130101) C04B 2235/3244 (20130101) C04B 2235/3262 (20130101) C04B 2235/3275 (20130101) C04B 2235/3279 (20130101) C04B 2235/3281 (20130101) C04B 2235/3282 (20130101) C04B 2235/3284 (20130101) C04B 2235/3287 (20130101) C04B 2235/3289 (20130101) C04B 2235/3293 (20130101) C04B 2235/3296 (20130101) C04B 2235/3418 (20130101) Electric solid-state devices not otherwise provided for H10N 60/0296 (20230201) H10N 60/857 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12016336 | Bowden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (lowa City, Iowa) |
| INVENTOR(S) | Ned B. Bowden (Iowa City, Iowa); Justin M. Carter (Iowa City, Iowa); Eric M. Brown (Iowa City, Iowa); Nimesh Ranasinghe (Iowa, Iowa); Arjun Paudel (Iowa City, Iowa); Erin E. Irish (Iowa City, Iowa) |
| ABSTRACT | The invention provides a compound of formula I: wherein X, Y, Z, R1, R2, and X+ have any of the values described in the specification. The compounds are useful to increase plant growth and/or to increase harvest yield. |
| FILED | Tuesday, February 28, 2023 |
| APPL NO | 18/115700 |
| ART UNIT | 1699 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 57/12 (20130101) Original (OR) Class A01N 57/16 (20130101) A01N 59/02 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 21/00 (20210801) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/06 (20130101) C07F 9/6578 (20130101) C07F 9/657118 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016531 | Rentschler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| INVENTOR(S) | Mark E. Rentschler (Boulder, Colorado); Gregory Formosa (Boulder, Colorado); Joseph M. Prendergast (Boulder, Colorado) |
| ABSTRACT | A self-propelled semi- or fully-autonomous robotic endoscope device is provided that include multi-degrees of freedom movement and may be sensor-enabled for colonoscopy procedures. The device may include two independently controlled motors configured to drive micro-pillared treads above and below the device, allowing for 2-degrees of freedom (DOF) skid-steering even in a collapsed lumen. The robotic device contains similar functionality of a traditional endoscope, such as a camera, adjustable LEDs, channels for insufflation and irrigation, and a tool port for common endoscopy instruments (e.g., forceps, snares, etc.). |
| FILED | Wednesday, May 06, 2020 |
| APPL NO | 16/868114 |
| ART UNIT | 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/31 (20130101) A61B 1/041 (20130101) Original (OR) Class A61B 1/00119 (20130101) A61B 1/0684 (20130101) A61B 34/20 (20160201) A61B 34/32 (20160201) A61B 34/71 (20160201) A61B 2034/301 (20160201) A61B 2034/2046 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016628 | Yao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Xincheng Yao (Hinsdale, Illinois); Tae Yun Son (Chicago, Illinois) |
| ABSTRACT | A multi-modal functional OCT imaging methodology and system are provided that enable concurrent intrinsic optical signal (IOS) imaging of stimulus-evoked neural activity and hemodynamic responses at capillary resolution. An OCT angiography (OCTA)-guided IOS analysis is used to separate neural-IOS and hemodynamic-IOS changes in the same retinal image sequence. The OCTA-guided IOS data processing used for this purpose differentiates two functional images, namely, a neural-IOS map and a hemodynamic-IOS map, from the same image dataset. |
| FILED | Tuesday, March 27, 2018 |
| APPL NO | 16/497071 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0008 (20130101) A61B 3/0025 (20130101) A61B 3/102 (20130101) Original (OR) Class A61B 3/1241 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/45 (20130101) G01J 3/0208 (20130101) G01J 2003/451 (20130101) Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 2207/10101 (20130101) G06T 2207/30041 (20130101) G06T 2211/404 (20130101) G06T 2219/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016779 | Lieberman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Jay R. Lieberman (Los Angeles, California); William Pannell (Los Angeles, California); Yong Chen (Los Angeles, California); Xuan Song (Los Angeles, California); Sofia Bougioukli (Los Angeles, California) |
| ABSTRACT | A method for repairing a bone defect of a patient includes providing a ceramic scaffold configured for filling the bone defect, loading the scaffold with growth factor transduced cells incorporating a gene that encodes a growth factor essential for bone formation, placing the ceramic scaffold with the growth factor transduced cells in or across the bone defect, and stabilizing the ceramic scaffold with the growth factor transduced cells in the patient until the bone defect is healed. An assembly for repairing a bone defect includes a ceramic scaffold configured for spanning the bone defect and a culture of live growth factor transduced cells incorporating a gene that encodes a growth factor essential for bone formation loaded onto the ceramic scaffold. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 16/337893 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/28 (20130101) A61F 2/30942 (20130101) Original (OR) Class A61F 2002/30235 (20130101) A61F 2002/30677 (20130101) A61F 2002/30784 (20130101) A61F 2310/00293 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/1875 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/10 (20130101) A61L 27/54 (20130101) A61L 27/3834 (20130101) A61L 2300/414 (20130101) A61L 2430/02 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017188 | Diallo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (Daejeon, South Korea) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (Daejeon, South Korea) |
| INVENTOR(S) | Mamadou S. Diallo (Pasadena, California); Madhusudhana Rao Kotte (Daejeon, South Korea); Alex Kuvarega (Daejeon, South Korea) |
| ABSTRACT | Described herein are mixed matrix filtration membranes and related, dendrimers, dendrimer particles, compositions, methods and systems and in particular mixed matrix filtration membranes with an embedded dendrimer particles and related compositions, methods, and systems wherein each dendrimer particle comprises at least two dendrimers each having at least two core chemical moieties having a core multiplicity Nc; branch cell units attached to the core chemical moiety or one to another, with the branch cell units attached one to another having a branch cells multiplicity Nb; and a number of surface functional groups Z presented on terminal branch cell units, wherein Z=NcNbG with G≤3. |
| FILED | Thursday, November 11, 2021 |
| APPL NO | 17/524572 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/025 (20130101) B01D 61/145 (20130101) B01D 67/0006 (20130101) B01D 67/0009 (20130101) B01D 67/0011 (20130101) B01D 69/12 (20130101) B01D 69/125 (20130101) B01D 69/141 (20130101) Original (OR) Class B01D 71/34 (20130101) B01D 71/56 (20130101) B01D 71/60 (20130101) B01D 2323/30 (20130101) B01D 2323/39 (20130101) B01D 2323/42 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/285 (20130101) C02F 1/444 (20130101) C02F 2101/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017276 | Hildreth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Colorado School of Mines (Golden, Colorado) |
| ASSIGNEE(S) | Colorado School of Mines (Golden, Colorado) |
| INVENTOR(S) | Owen Hildreth (Lakewood, Colorado); Meredith Heilig (Golden, Colorado); Sanaz Yazdanparast (Golden, Colorado); Subbarao Raikar (Golden, Colorado) |
| ABSTRACT | A method is provided to remove a selective amount of material from a metal component fabricated by additive manufacturing in a self-terminating manner. The method can be used to remove support structures and trapped powder from a metal component as well as to smooth surfaces of a 3D printed metal component. In some embodiments, selected surfaces of the metal component are treated to make the selected surfaces at least one of mechanically and chemically unstable. The unstable portion of the metal support can then be removed chemically, electrochemically, or through vapor-phase etching. The method can be used for processing any fluid or vapor-accessible regions and surfaces of a 3D printed metal component. |
| FILED | Thursday, March 17, 2022 |
| APPL NO | 17/697814 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/40 (20210101) B22F 10/62 (20210101) Original (OR) Class B22F 10/68 (20210101) B22F 2301/10 (20130101) B22F 2301/15 (20130101) B22F 2301/052 (20130101) B22F 2301/205 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/20 (20200101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/12 (20130101) C23F 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017347 | Aukes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel Aukes (Gilbert, Arizona); Mohammad Sharifzadeh (San Diego, California); Yuhao Jiang (Tempe, Arizona); Nicholas Gravish (San Diego, California); Mingsong Jiang (Anshan, China PRC) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Daniel Aukes (Gilbert, Arizona); Mohammad Sharifzadeh (San Diego, California); Yuhao Jiang (Tempe, Arizona); Nicholas Gravish (San Diego, California); Mingsong Jiang (Anshan, China PRC) |
| ABSTRACT | A device includes a tube and a sleeve configured to at least partially encircle a portion the tube along its length. The tube is flexible and airtight and defines a longitudinal axis along a center of the tube, and is configured to bend along the longitudinal axis upon at least partial evacuation of the tube to form a joint. The joint defines a joint angle relative to the longitudinal axis, thereby approximating a revolute joint with torsional stiffness. Actuating a joint includes partially evacuating a flexible tube defining a longitudinal axis, thereby forming a bend in the tube at an angle with respect to the longitudinal axis at a perimeter of a rigid sleeve at least partially encircling the tube, and restoring a neutral pressure to the tube, thereby removing the bend in the tube. |
| FILED | Friday, October 21, 2022 |
| APPL NO | 17/971062 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/06 (20130101) B25J 9/142 (20130101) B25J 17/0241 (20130101) B25J 18/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017983 | Agrawal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Rakesh Agrawal (West Lafayette, Indiana); Zewei Chen (West Lafayette, Indiana); Peter Oladipupo (West Lafayette, Indiana) |
| ABSTRACT | Systems and processes for dehydrogenating one or more alkanes using electrically heated dehydrogenation reactors. The source of electric energy or power can be a power grid, solar panel, windmill, hydropower, nuclear power, fuel cell, gas turbines, steam turbines, portable generator or the like. The systems and processes provided herein result in a simpler dehydrogenation process which is particularly beneficial at a small scale and at remote locations, including the well site. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/169086 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0013 (20130101) B01J 19/2415 (20130101) B01J 2219/00081 (20130101) B01J 2219/00085 (20130101) B01J 2219/00132 (20130101) Acyclic or Carbocyclic Compounds C07C 5/327 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018099 | Salas de la Cruz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); Rowan University (Glassboro, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); Rowan University (Glassboro, New Jersey) |
| INVENTOR(S) | David Salas de la Cruz (Camden, New Jersey); Xiao Hu (Glassboro, New Jersey); Stacy Love (Camden, New Jersey); David Verrill (Camden, New Jersey) |
| ABSTRACT | The present disclosure provides methods of controlling the size of cellulose crystals by mixing a first composition comprising cellulose and coagulating this mixture with varying concentrations of hydrogen peroxide. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/218372 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Separation B01D 67/0011 (20130101) B01D 71/10 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/447 (20130101) Polysaccharides; Derivatives Thereof C08B 15/08 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/041 (20170501) C08K 3/042 (20170501) C08K 11/00 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018136 | Rabnawaz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | Muhammad Rabnawaz (East Lansing, Michigan); Muhammad Naveed (East Lansing, Michigan) |
| ABSTRACT | The disclosure relates to thermally reversibly crosslinked polyolefins (TRC-PO) and methods for making the same. A TRC-PO can be formed by reactive melt-processing a mixture including (i) a polyolefin, (ii) an initiator, and (iii) a reversible crosslinker. The reversible crosslinker includes (A) a grafting agent moiety selected from unsaturated cyclic anhydrides, unsaturated cyclic imides, cyclic nitroxides, and ring-opened analogs thereof, and (B) a crosslinking moiety bound to the cyclic grafting agent moiety. This reactive melt-processing, for example including reactive extrusion, forms a thermally reversibly crosslinked (TRC) polyolefin with polyolefin chains reversibly crosslinked via the reversible crosslinkers, which provide dynamic covalent bonds, such as siloxanes and esters, that are amenable to melt re-processing to re-from or otherwise re-use the TRC-PO while still retaining the reversible crosslinks after re-processing. Catalysts and additives such as rheology modifiers can be added to the melt-processing mixture. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/532610 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/243 (20130101) Original (OR) Class C08J 11/18 (20130101) C08J 2323/06 (20130101) C08J 2323/12 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/14 (20130101) C08K 5/20 (20130101) C08K 5/0025 (20130101) C08K 5/053 (20130101) C08K 5/1539 (20130101) Compositions of Macromolecular Compounds C08L 51/06 (20130101) C08L 2207/062 (20130101) C08L 2312/00 (20130101) C08L 2314/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018193 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Biwu Ma (Tallahassee, Florida); Chenkun Zhou (Tallahassee, Florida); Haoran Lin (Tallahassee, Florida); Yu Tian (Tallahassee, Florida) |
| ABSTRACT | Bulk assemblies are provided, which may have desirable photoluminescence quantum efficiencies. The bulk assemblies may include two or more metal halides, and a wide band gap organic network. The wide band gap organic network may include organic cations. The metal halides may be disposed in the wide band gap organic network. Light emitting composite materials also are provided. |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/180601 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class C09K 11/664 (20130101) C09K 11/7428 (20130101) C09K 11/7734 (20130101) C09K 2211/1007 (20130101) C09K 2211/1011 (20130101) C09K 2211/1014 (20130101) C09K 2211/1018 (20130101) C09K 2211/1022 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/20 (20130101) H05B 33/145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018195 | Tharkur et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Jeremy Tharkur (Miami, Florida); Swadeshmukul Santra (Orlando, Florida) |
| ABSTRACT | A method for preparing a light sensitive particle that uses at least one metal precursor material and at least one dopant precursor material mixed in solution absent a surfactant. Upon an optional adjustment of pH to about 3 to about 6, a light-sensitive particle comprising a metal-dopant material may be formed and separated from the solution. The light-sensitive particle may comprise a Q-dot particle. Also described are the particles themselves. |
| FILED | Tuesday, May 31, 2022 |
| APPL NO | 17/828510 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/574 (20130101) Original (OR) Class C09K 11/0805 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 22/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018304 | Siddiqui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Michael Shareef Siddiqui (San Mateo, California); Christina D. Smolke (Menlo Park, California) |
| ABSTRACT | Host cells that are engineered to produce benzylisoquinoline alkaloid (BIAS) precursors, such as norcoclaurine (NC) and norlaudanosoline (NL), are provided. The host cells may have one or more engineered modifications selected from: a feedback inhibition alleviating mutation in a enzyme gene; a transcriptional modulation modification of a biosynthetic enzyme gene; an inactivating mutation in an enzyme; and a heterologous coding sequence. Also provided are methods of producing a BIA of interest or a precursor thereof using the host cells and compositions, e.g., kits, systems etc., that find use in methods of the invention. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/386204 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0071 (20130101) C12N 9/90 (20130101) C12N 9/1085 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/24 (20130101) C12P 13/001 (20130101) C12P 13/225 (20130101) C12P 17/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018307 | Zhan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jixun Zhan (North Logan, Utah) |
| ASSIGNEE(S) | UTAH STATE UNIVERSITY (North Logan, Utah) |
| INVENTOR(S) | Jixun Zhan (North Logan, Utah) |
| ABSTRACT | The present invention relates to an in vitro or in vivo process for producing a glucuronide comprising a glucuronic acid moiety bound to a phenolic hydroxyl group or a phenolic carboxyl group. Also provided are expression vectors, nucleic acids, polypeptides, and recombinant microbial cells useful in carrying out the process and prodrugs produced by the process. |
| FILED | Friday, August 26, 2022 |
| APPL NO | 17/822733 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/1051 (20130101) C12N 9/1241 (20130101) C12N 15/62 (20130101) C12N 15/63 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/60 (20130101) Original (OR) Class Enzymes C12Y 101/01022 (20130101) C12Y 204/01017 (20130101) C12Y 207/07009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018354 | Vo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NanoAL LLC (Ashland, Massachusetts) |
| ASSIGNEE(S) | NanoAL LLC (Ashland, Massachusetts) |
| INVENTOR(S) | Nhon Q. Vo (Winchester, Massachusetts); Evander Ramos (Los Angeles, California); Davaadorj Bayansan (Glenview, Illinois); Francisco U. Flores (Lowell, Massachusetts) |
| ABSTRACT | Aluminum-manganese-zirconium-inoculant alloys that exhibit high strength, high ductility, high creep resistance, high thermal stability, and durability, and can be fabricated utilizing recycled used aluminum cans. |
| FILED | Friday, September 06, 2019 |
| APPL NO | 16/562968 |
| ART UNIT | 1738 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/047 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018894 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Chen Li (Chapin, South Carolina); Jamil Khan (Columbia, South Carolina); Xinyu Huang (Columbia, South Carolina); Tanvir Farouk (Irmo, South Carolina); Raikan Dawas (Cayce, South Carolina); Wei Chang (Columbia, South Carolina); Pengtao Wang (Columbia, South Carolina); Mohammad Alwazzan (Columbia, South Carolina); Guanghan Huang (Columbia, South Carolina) |
| ABSTRACT | Sweating-boosted air cooled heat-pipe condensers employing a nanowick micro fin structure to form a sweating boosted heat dissipation system, wherein the nanowicks may be layered. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 16/824777 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Steam or Vapour Condensers F28B 1/06 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/043 (20130101) F28D 15/046 (20130101) Original (OR) Class F28D 15/0275 (20130101) F28D 15/0283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018990 | Ku et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Pei-Cheng Ku (Ann Arbor, Michigan); Jingyang Sui (Atlanta, Georgia); Kunook Chung (Ann Arbor, Michigan) |
| ABSTRACT | A device includes a substrate and a set of force sensors supported by the substrate. Each force sensor includes a pillar extending outward from the substrate, each pillar comprising a stack of semiconductor layers, the stack of semiconductor layers being configured to emit light upon biasing of the stack of semiconductor layers, and post disposed along only a portion of a perimeter of the pillar such that, taken together, the pillar and the post have an asymmetrical cross-sectional shape. Each pillar has a cross-section elongated along an axis. An orientation of the axis, and a peripheral position of the portion of the perimeter at which the post is disposed, differ across the set of force sensors such that a variation in light emitted by the stack of semiconductor layers of one or more of the force sensors is indicative of a direction of a shear force applied to the set of force sensors. |
| FILED | Wednesday, January 22, 2020 |
| APPL NO | 17/425205 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0029 (20130101) B81B 2201/0264 (20130101) B81B 2203/0118 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/24 (20130101) Original (OR) Class G01L 1/25 (20130101) G01L 5/226 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 25/0753 (20130101) H01L 33/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019018 | Scarcelli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| INVENTOR(S) | Giuliano Scarcelli (Washington, District of Columbia); Romanus Hutchins (College Park, Maryland); Giulia Zanini (University Park, Maryland) |
| ABSTRACT | A full-field microscopy method for detection of Brillouin-scattered light includes illuminating a two-dimensional plane in a sample with interrogating light having a first wavelength. Light emitted from the two-dimensional plane can be collected. The emitted light comprises Brillouin-scattered light resulting from interaction of the interrogating light with the sample. The Brillouin-scattered light can have a second wavelength shifted from the first wavelength. The collected light can be passed through a spectrally-selective assembly comprising a gas or vapor illuminated by pumping light. After the spectrally-selective assembly, the Brillouin-scattered light from multiple points in the two-dimensional plane in the sample can be simultaneously detected by an electro-optical sensor. In some embodiments, the spectrally-selective assembly can be altered by changing a wavelength or polarization of the pumping light to allow acquisition of a Brillouin spectrum. |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 17/393532 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/636 (20130101) Original (OR) Class G01N 2021/638 (20130101) Optical Elements, Systems, or Apparatus G02B 21/04 (20130101) G02B 21/361 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019130 | Englund |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | Chemical-shift nuclear magnetic resonance (NMR) spectroscopy involves measuring the effects of chemical bonds in a sample on the resonance frequencies of nuclear spins in the sample. Applying a magnetic field to the sample causes the sample nuclei to emit alternating current magnetic fields that can be detected with color centers, which can act as very sensitive magnetometers. Cryogenically cooling the sample increases the sample's polarization, which in turn enhances the NMR signal strength, making it possible to detect net nuclear spins for very small samples. Flash-heating the sample or subjecting it to a magic-angle-spinning magnetic field (instead of a static magnetic field) eliminates built-in magnetic field inhomogeneities, improving measurement sensitivity without degrading the sample polarization. Tens to hundreds of small, cryogenically cooled sample chambers can be integrated in a semiconductor substrate interlaced with waveguides that contain color centers for optically detected magnetic resonance measurements of the samples' chemical-shift NMR frequencies. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/465895 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/31 (20130101) G01R 33/46 (20130101) Original (OR) Class G01R 33/282 (20130101) G01R 33/323 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019173 | Kassas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Zak M. Kassas (Irvine, California); Mahdi Maaref (Irvine, California); Joe Khalife (Costa Mesa, California) |
| ABSTRACT | A vehicular simultaneous localization and mapping may fuse lidar data and pseudoranges extracted from ambient cellular LTE towers. An ICP algorithm may be used to extract odometry measurements from successive lidar scans. A robust and computationally efficient feature extraction method may be used to detect edge lines and feature points from the lidars point cloud. Then, a point registration technique using a maximum likelihood approach allows the estimation of the covariance of the odometry error, which is used in EKF propagation. The proposed approach consists of a mapping mode when GNSS signals are available and subsequently a SLAM mode when GNSS signals become unavailable. The cellular transmitters states, namely position and clock bias and clock drift, are continuously estimated in both modes. Simulation and experimental results validate the accuracy of these systems and methods, and provides lane-level localization without GNSS signals. |
| FILED | Friday, August 23, 2019 |
| APPL NO | 17/270763 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/188 (20200801) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/89 (20130101) G01S 19/485 (20200501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019268 | Vercruysse et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Dries J. F. Vercruysse (Palo Alto, California); Jelena Vuckovic (Palo Alto, California) |
| ABSTRACT | A dispersion-engineered 2D optical phased array device includes optical slow light waveguides [202, 208, 218] arranged parallel to each other; waveguide bends [206, 216] optically coupling ends of adjacent waveguides of the optical slow light waveguides to form a serpentine optical configuration; wherein the optical slow light waveguides comprise first waveguides of a first waveguide type and second waveguides of a second waveguide type, wherein the first waveguides and the second waveguides are arranged adjacent to each other and alternate with each other; wherein the optical slow light waveguides comprise phased array sections forming a phased array [214], wherein first waveguides and second waveguides have dispersion slopes of opposite sign and the same group index; wherein the optical slow light waveguides comprise slow light delay waveguide sections [210] that provide a delay between adjacent waveguides. |
| FILED | Monday, July 26, 2021 |
| APPL NO | 18/015930 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/12011 (20130101) Original (OR) Class G02B 6/12016 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/292 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019271 | Reano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Ronald Reano (Columbus, Ohio); Jonathan Nagy (Columbus, Ohio); Karan Prabhakar (Columbus, Ohio); Ryan Patton (Columbus, Ohio) |
| ABSTRACT | A fiber-to-fiber system for multi-layer ferroelectric on insulator waveguide devices is described. The system comprises a fiber-to-chip coupler that couples light from a standard optical fiber to multi-layer ferroelectric on insulator waveguides. The multi-layer ferroelectric on insulator waveguides are integrated with electrodes to implement an optical device, an electro-optical device, or a non-linear optical device, such as an electro-optical modulator, with microwave and optical waveguide crossings compatible with packaging. A second fiber-to-chip coupler outputs the light from the multi-layer ferroelectric on insulator device to a standard optical fiber. |
| FILED | Monday, April 17, 2023 |
| APPL NO | 18/301520 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) Original (OR) Class G02B 6/12002 (20130101) G02B 6/12019 (20130101) G02B 2006/12147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12020165 | Ozcan et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Aydogan Ozcan (Los Angeles, California); Yair Rivenson (Los Angeles, California); Yichen Wu (Los Angeles, California) |
| ABSTRACT | A trained deep neural network transforms an image of a sample obtained with a holographic microscope to an image that substantially resembles a microscopy image obtained with a microscope having a different microscopy image modality. Examples of different imaging modalities include bright-field, fluorescence, and dark-field. For bright-field applications, deep learning brings bright-field microscopy contrast to holographic images of a sample, bridging the volumetric imaging capability of holography with the speckle-free and artifact-free image contrast of bright-field microscopy. Holographic microscopy images obtained with a holographic microscope are input into a trained deep neural network to perform cross-modality image transformation from a digitally back-propagated hologram corresponding to a particular depth within a sample volume into an image that substantially resembles a microscopy image of the sample obtained at the same particular depth with a microscope having the different microscopy image modality. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 17/294384 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/0008 (20130101) G02B 21/365 (20130101) Holographic Processes or Apparatus G03H 1/0005 (20130101) G03H 1/268 (20130101) G03H 2001/005 (20130101) Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/70 (20240101) G06T 7/50 (20170101) G06T 2207/10056 (20130101) G06T 2207/10064 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/764 (20220101) G06V 20/69 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12020682 | Mandel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | Research Foundation of the City University of New York (New York, New York) |
| INVENTOR(S) | Michael Mandel (Brooklyn, New York); Soumi Maiti (Brooklyn, New York) |
| ABSTRACT | A method for Parametric resynthesis (PR) producing an audible signal. A degraded audio signal is received which includes a distorted target audio signal. A prediction model predicts parameters of the audible signal from the degraded signal. The prediction model was trained to minimize a loss function between the target audio signal and the predicted audible signal. The predicted parameters are provided to a waveform generator which synthesizes the audible signal. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 17/441063 |
| ART UNIT | 2654 — Audio Signals |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 13/047 (20130101) Original (OR) Class G10L 21/0264 (20130101) G10L 25/18 (20130101) G10L 25/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12020828 | Saffman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Mark Saffman (Madison, Wisconsin) |
| ABSTRACT | A system and method for controlling particles using projected light are provided. In some aspects, the method includes generating a beam of light using an optical source, and directing the beam of light to a beam filter comprising a first mask, a first lens, a second mask, and a second lens. The method also includes forming an optical pattern using the beam filter, and projecting the optical pattern on a plurality of particles to control their locations in space. |
| FILED | Friday, January 03, 2020 |
| APPL NO | 17/420542 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021195 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | Yiying Wu (Columbus, Ohio); William McCulloch (Columbus, Ohio) |
| ABSTRACT | The present technology is directed to fluorinated alkylsulfonamide electrolyte salts with high solubility, conductivity, and electrochemical stability as well as batteries incorporating fluorinated alkylsulfonamide salts. In any aspect and/or embodiment herein of the present technology, the battery may include a separator disposed between the cathode and the anode. The separator may be a porous paper, porous ceramic, or porous polymer separator. |
| FILED | Monday, January 06, 2020 |
| APPL NO | 17/418644 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 311/09 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/48 (20130101) H01M 4/583 (20130101) H01M 4/621 (20130101) H01M 10/0568 (20130101) Original (OR) Class H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021201 | Ergen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Onur Ergen (Berkeley, California); Alexander K. Zettl (Kensington, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to Li-ion batteries. In one aspect an electrolyte structure for use in a battery comprises an electrolyte and an interconnected boron nitride structure disposed in the electrolyte. |
| FILED | Tuesday, January 11, 2022 |
| APPL NO | 17/573488 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/056 (20130101) H01M 10/0525 (20130101) H01M 10/4235 (20130101) Original (OR) Class H01M 2300/0025 (20130101) H01M 2300/0045 (20130101) H01M 2300/0071 (20130101) H01M 2300/0085 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021507 | Safavi-Naeini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Amir H. Safavi-Naeini (Palo Alto, California); Marek Pechal (Zurich, Switzerland); Patricio Arrangoiz-Arriola (Clarksville, Maryland); Edward Alexander Wollack (Clarksville, Maryland) |
| ABSTRACT | A coupled storage qubit nanomechanical resonator in a processing qubit superconducting circuit is provided that includes a phononic crystal resonator (PCR) film disposed on a substrate, where the PCR film includes a defect mode in a bandgap of the PCR film where a storage qubit is encoded, a pair of electrodes generate voltages within the PCR film, where the defect is dimensioned to support a unique electrical potential generated by a local mechanical phonon mode of the PCR film, where a unique resonance frequency that is dependent on the defect dimensions is output from the PCR film, a coupling capacitor that is coupled to the PCR film, where the coupling capacitor is disposed to receive the output unique resonance frequency, and a processing qubit, where the processing qubit is capacitively coupled to the PCR film by the coupling capacitor, where the storage qubits are connected to the processing qubits. |
| FILED | Monday, August 26, 2019 |
| APPL NO | 16/551004 |
| ART UNIT | 2124 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) G06N 10/40 (20220101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12017091 | Friedman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Integrated Sensors, LLC (Palm Beach Gardens, Florida) |
| ASSIGNEE(S) | Integrated Sensors, LLC (Palm Beach Gardens, Florida) |
| INVENTOR(S) | Peter S. Friedman (Palm Beach Gardens, Florida) |
| ABSTRACT | Embodiments are directed generally to an ionizing-radiation beamline monitoring system that includes a vacuum chamber structure with vacuum compatible flanges through which an incident ionizing-radiation beam enters the monitoring system. Embodiments further include at least one scintillator within the vacuum chamber structure that can be at least partially translated in the ionizing-radiation beam while oriented at an angle greater than 10 degrees to a normal of the incident ionizing-radiation beam, a machine vision camera coupled to a light-tight structure at atmospheric/ambient pressure that is attached to the vacuum chamber structure by a flange attached to a vacuum-tight viewport window with the camera and lens optical axis oriented at an angle of less than 80 degrees with respect to a normal of the scintillator, and at least one ultraviolet (“UV”) illumination source facing the scintillator in the ionizing-radiation beam for monitoring a scintillator stability comprising scintillator radiation damage. |
| FILED | Thursday, September 07, 2023 |
| APPL NO | 18/462606 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101) A61N 5/1045 (20130101) A61N 5/1048 (20130101) A61N 5/1049 (20130101) A61N 5/1064 (20130101) A61N 5/1067 (20130101) Original (OR) Class A61N 5/1077 (20130101) A61N 2005/1059 (20130101) A61N 2005/1087 (20130101) Measurement of Nuclear or X-radiation G01T 1/29 (20130101) G01T 1/40 (20130101) G01T 1/1612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017196 | Zheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Richard F. Zheng (Lake Oswego, Oregon); Robert S. Wegeng (Richland, Washington); Paul H. Humble (Kennewick, Washington); Dustin D. Caldwell (Portland, Connecticut); Richard B. Diver (Albuquerque, New Mexico) |
| ABSTRACT | Reactors are provided that can include a first set of fluid channels and a second set of fluid channels oriented in thermal contact with the first set of fluid channels. The reactor assemblies can also provide where the channels of either one or both of the first of the set of fluid channels are non-linear. Other implementations provide for at least one of the first set of fluid channels being in thermal contact with a plurality of other channels of the second set of fluid channels. Reactor assemblies are also provided that can include a first set of fluid channels defining at least one non-linear channel having a positive function, and a second set of fluid channels defining at least another non-linear channel having a negative function in relation to the positive function of the one non-linear channel of the first set of fluid channels. Processes for distributing energy across a reactor are provided. The processes can include transporting reactants via a first set of fluid channels to a second set of fluid channels, and thermally engaging at least one of the first set of fluid channels with at least two of the second set of fluid channels. |
| FILED | Tuesday, June 07, 2022 |
| APPL NO | 17/834673 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0013 (20130101) B01J 19/0093 (20130101) Original (OR) Class B01J 2219/00081 (20130101) B01J 2219/00788 (20130101) B01J 2219/00804 (20130101) B01J 2219/00873 (20130101) B01J 2219/00995 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/16 (20130101) C01B 3/38 (20130101) C01B 2203/063 (20130101) C01B 2203/066 (20130101) C01B 2203/0233 (20130101) C01B 2203/0283 (20130101) C01B 2203/0833 (20130101) C01B 2203/1241 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 20/20 (20180501) F24S 90/00 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017255 | Kumar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sortera Alloys, Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | Sortera Technologies, Inc. (Markle, Indiana) |
| INVENTOR(S) | Nalin Kumar (Fort Worth, Texas); Manuel Gerardo Garcia, Jr. (Fort Wayne, Indiana) |
| ABSTRACT | Systems and methods for classifying and sorting materials in order to produce a collection of materials that are composed of a particular chemical composition in the aggregate. The system may utilize a vision system and one or more sensor systems, which may implement a machine learning system in order to identify or classify each of the materials. The sorting is then performed as a function of the classifications. |
| FILED | Wednesday, March 16, 2022 |
| APPL NO | 17/696831 |
| ART UNIT | 3653 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 5/04 (20130101) B07C 5/34 (20130101) B07C 5/342 (20130101) B07C 5/3422 (20130101) Original (OR) Class B07C 2501/0054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017279 | Tappan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Bryce Tappan (Santa Fe, New Mexico); Andrew Schmalzer (Los Alamos, New Mexico); Alexander H. Mueller (Santa Fe, New Mexico) |
| ABSTRACT | Processes for tailoring the macroscopic shape, metallic composition, mechanical properties, and pore structure of nanoporous metal foams prepared through combustion synthesis via direct write 3D printing of metal energetic ligand precursor inks made with water and an organic thickening agent are disclosed. Such processes enable production of never before obtainable metal structures with hierarchical porosity, tailorable from the millimeter size regime to the nanometer size regime. Structures produced by these processes have numerous applications including, but not limited to, catalysts, heat exchangers, low density structural materials, biomedical implants, hydrogen storage medium, fuel cells, and batteries. |
| FILED | Tuesday, January 17, 2023 |
| APPL NO | 18/098035 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/1121 (20130101) Original (OR) Class B22F 10/00 (20210101) B22F 10/60 (20210101) B22F 2998/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/52 (20130101) Alloys C22C 1/08 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017423 | Kiefer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Seth M. Kiefer (Kansas City, Missouri); Phillip C. Davis (Kansas City, Missouri) |
| ABSTRACT | A caul for debulking a composite part broadly includes opposing first and second surfaces, a plurality of through-holes, and a coating. The first surface may have a curvature complementary to a shape of the composite part. The through-holes pass through the caul from the first surface to the second surface. The coating may be a chemically inert material to ensure the caul does not affect the composite part. The caul is configured to be positioned against the composite part for debulking. The caul may be made out of silicone rubber or any other suitable material and may be reusable. |
| FILED | Friday, September 09, 2022 |
| APPL NO | 17/941590 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/3842 (20130101) B29C 70/342 (20130101) B29C 70/544 (20210501) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2819/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018066 | Lillo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Antonietta Maria Lillo (Los Alamos, New Mexico); Nileena Velappan (Los Alamos, New Mexico); Geoffrey S. Waldo (Los Alamos, New Mexico) |
| ABSTRACT | The invention provides antibodies that specifically bind the SARS-CoV-2 receptor binding domain. The antibodies are useful in treating SARS-CoV-2 virus infection and in diagnostic methods, agents, and kits thereof. |
| FILED | Friday, October 29, 2021 |
| APPL NO | 17/514903 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/33 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018104 | Hartmann-Thompson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | 3M INNOVATIVE PROPERTIES COMPANY (St. Paul, Minnesota) |
| ASSIGNEE(S) | 3M Innovative Properties Company (St. Paul, Minnesota) |
| INVENTOR(S) | Claire Hartmann-Thompson (Lake Elmo, Minnesota); Mark J. Pellerite (Woodbury, Minnesota); John C. Thomas (St. Paul, Minnesota); Marina M. Kaplun (Woodbury, Minnesota) |
| ABSTRACT | A crosslinkable copolymer is provided. The crosslinkable copolymer has pendant cationic nitrogen-containing groups with some, but not all, of these pendant groups further including a (meth)acryloyl group. The (meth)acryloyl groups can react to form a crosslinked copolymer that is ionically conductive. The crosslinked copolymer can be used to provide an anion exchange membrane that can be used in electrochemical cells such as fuel cells, electrolyzers, batteries, and electrodialysis cells. |
| FILED | Thursday, December 05, 2019 |
| APPL NO | 17/309391 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Separation B01D 71/281 (20220801) B01D 71/401 (20220801) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/14 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/30 (20130101) C08F 212/08 (20130101) C08F 212/18 (20200201) Original (OR) Class Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 13/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 50/414 (20210101) H01M 50/497 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018390 | Olson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | Luke C. Olson (Columbia, South Carolina); Kathryn E. Metzger (Columbia, South Carolina); Edward J. Lahoda (Edgewood, Pennsylvania) |
| ABSTRACT | A method is described herein that produces UN from UF6 in at most two steps comprising UF6→intermediate→UN. The principle of the reaction is that in a first step, UF6 would be reduced to UxNy, where x may be an integer selected from 1 and 3, and y is an integer selected from 1 and 2. Reduction occurs at or near the surface of a gaseous membrane electrode where it is also in contact with a nitrogen bearing salt. In a second step, UxNy decomposes to UN and N2 gas, either in the same reactor as the first step or after removal to a separate unit for further processing. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/753548 |
| ART UNIT | 1759 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/01 (20210101) Original (OR) Class C25B 1/50 (20210101) C25B 9/09 (20210101) C25B 15/083 (20210101) Nuclear Reactors G21C 3/62 (20130101) G21C 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019746 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Jared M. Smith (Oak Ridge, Tennessee); Luke Koch (Oak Ridge, Tennessee) |
| ABSTRACT | An adaptive malware writing system includes a targeting engine that classifies malware candidates as a malicious candidate or a benign candidate through a surrogate model. The surrogate model assigns a weight to each byte of the malware candidates through a saliency vector. The sum of the weights render a malware classification score. An alteration engine alters a binary form of the malware candidates classified as malware by executing a functional analysis that traces application program interface calls and memory. The alteration engine alters the binary form of the malware candidates classified as malware to render a synthesized malware. The malware analysis determines if the synthesized malware is operational by comparing an image of the synthesized malware to an image of at least one of the plurality of malware candidates. A target classifier engine identifies the vulnerabilities of a targeted computer. |
| FILED | Tuesday, June 28, 2022 |
| APPL NO | 17/851229 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/14 (20130101) G06F 21/564 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021185 | Maughan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Annalise Elizabeth Maughan (Westminster, Colorado) |
| ABSTRACT | Disclosed herein are new argyrodite compositions of matter, including, for example, Li6PS5CN, and methods for making the same. |
| FILED | Thursday, March 18, 2021 |
| APPL NO | 17/206100 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021187 | Visco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Vitaliy Nimon (San Francisco, California); Alexei Petrov (Walnut Creek, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California) |
| ABSTRACT | Chemically treating ionically conductive sulfide glass solid electrolyte separators or separator layers can improve performance. In particular, treatment involving chemically etching a surface or surface region of the sulfide glass separator to blunt, lessen or remove edge defects or surface flaws, and/or to enhance surface smoothness is cost effective, reliable and well suited for high production environments compared to physical methods of removing scratches or smoothing surfaces, such as mechanical grinding and polishing. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/303708 |
| ART UNIT | 1716 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/321 (20130101) C03C 4/14 (20130101) C03C 15/02 (20130101) C03C 2204/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021201 | Ergen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Onur Ergen (Berkeley, California); Alexander K. Zettl (Kensington, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to Li-ion batteries. In one aspect an electrolyte structure for use in a battery comprises an electrolyte and an interconnected boron nitride structure disposed in the electrolyte. |
| FILED | Tuesday, January 11, 2022 |
| APPL NO | 17/573488 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/056 (20130101) H01M 10/0525 (20130101) H01M 10/4235 (20130101) Original (OR) Class H01M 2300/0025 (20130101) H01M 2300/0045 (20130101) H01M 2300/0071 (20130101) H01M 2300/0085 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021202 | Sloop et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hulico LLC (Bend, Oregon) |
| ASSIGNEE(S) | HULICO LLC (Bend, Oregon) |
| INVENTOR(S) | Steven E. Sloop (Bend, Oregon); Lauren E. Crandon (Bend, Oregon) |
| ABSTRACT | Examples are disclosed of methods to deactivate a lithium-containing battery. One example provides a method for discharging a lithium-containing battery, the method comprising adding the lithium-containing battery to a vessel, adding an oxidizing fluid to the vessel, adding carbon dioxide to the vessel, pressurizing the vessel, heating the vessel to form lithium carbonate within the lithium-containing battery, reducing heat and pressure in the vessel, and removing the battery from the vessel. |
| FILED | Wednesday, November 11, 2020 |
| APPL NO | 17/095698 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 10/54 (20130101) H01M 10/0525 (20130101) H01M 10/4235 (20130101) H01M 10/4242 (20130101) Original (OR) Class Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/84 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021220 | Amine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Khalil Amine (Oakbrook, Illinois); Tongchao Liu (Westmont, Illinois); Jun Lu (Naperville, Illinois) |
| ABSTRACT | A cathode material comprising: a cathode active material of formula LiNixMnyCozO2 or NaNixMnyCozO2 and having a partial or whole particle concentration gradient, wherein at least two or three elements concentration gradually change in the part or whole particle from the center part to the surface part of the particle (i.e. along a vector radius); 0.5<x≤1, 0≤y≤0.33, 0≤z≤0.33. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/133804 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) Original (OR) Class H01M 4/364 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/1391 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021226 | Amine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois); Bayerische Motoren Werke Aktiengesellschaft (Munich, Germany) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois); BAYERISCHE MOTOREN WERKE AKTIENGESELLSCHAFT (Munich, Germany) |
| INVENTOR(S) | Khalil Amine (Oakbrook, Illinois); Xiaoqiao Zeng (Naperville, Illinois); Zonghai Chen (Bolingbrook, Illinois); Filippo Maglia (Munich, Germany) |
| ABSTRACT | An active cathode material containing particles with a core containing a lithium transition metal oxide, each core at least partially encapsulated by a layer including the lithium transition metal oxide and dopant cation; and an outer layer containing metal oxide; wherein the dopant cation is selected from the group consisting of Al, Ti, Sn, Mg, Zr, Cu, Fe, Ca, W, Ga, Sc, Y, La, Hf, V, In, Nb, Ta, and any combination of two or more thereof; and the dopant cation is present in an amount of 10 wt. % or less of the particle. |
| FILED | Friday, June 30, 2017 |
| APPL NO | 15/640100 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/0471 (20130101) H01M 4/483 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/625 (20130101) H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021238 | Visco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California); Vitaliy Nimon (San Francisco, California) |
| ABSTRACT | Batteries, component structures and manufacturing methods, in particular including a glassy embedded battery electrode assembly having a composite material structure composed of interpenetrating material components including a porous electroactive network including a solid electroactive material, and a continuous glassy medium including a Li ion conducting sulfide glass, can achieve enhanced power output, reduced charging time and/or improved cycle life. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/303707 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) Original (OR) Class H01M 4/0471 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 2004/028 (20130101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021246 | Haile et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); University of Maryland, College Park (College Park, Maryland) |
| INVENTOR(S) | Sossina M. Haile (Evanston, Illinois); Sihyuk Choi (Evanston, Illinois); Christopher James Kucharczyk (Evanston, Illinois); Yangang Liang (Richland, Washington); Xiaohang Zhang (North Potomac, Maryland); Ichiro Takeuchi (Laurel, Maryland) |
| ABSTRACT | Materials for electrochemical cells are provided. BaZr0.4Ce0.4M0.2O3 compounds, where M represents one or more rare earth elements, are provided for use as electrolytes. PrBa0.5Sr0.5Co2−xFexO5+δ is provided for use as a cathode. Also provided are electrochemical cells, such as protonic ceramic fuel cells, incorporating the compounds as electrolytes and cathodes. |
| FILED | Friday, November 11, 2022 |
| APPL NO | 17/985218 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 25/02 (20130101) C01G 25/006 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/861 (20130101) H01M 4/881 (20130101) H01M 4/8657 (20130101) H01M 4/8828 (20130101) H01M 4/8867 (20130101) H01M 4/9033 (20130101) Original (OR) Class H01M 4/9066 (20130101) H01M 8/126 (20130101) H01M 8/1213 (20130101) H01M 8/1246 (20130101) H01M 8/1253 (20130101) H01M 2008/1293 (20130101) H01M 2300/0074 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021452 | Ye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Zichao Ye (El Cerrito, California); Robert Pilawa-Podgurski (Alameda, California) |
| ABSTRACT | A switched-capacitor (SC) network in an SC converter is controlled to operate at varying resonant modes to achieve high conversion ratio efficiency, at a low circuit component count. These power converters are suited to numerous application areas including improving energy efficiency of data centers. A family of resonant switched capacitor (SC) converters with multiple operating phases are presented “Multi-Resonant SC Converters”. Described in detail are an 8-to-1 Multi-Resonant-Doubler (MRD) converter and a 6-to-1 Cascaded Series-Parallel (CaSP). The topology of these converters make them amenable to combining like units in parallel toward reaching higher power levels. |
| FILED | Friday, May 19, 2023 |
| APPL NO | 18/320879 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/0043 (20210501) H02M 1/0058 (20210501) H02M 1/0095 (20210501) H02M 3/07 (20130101) Original (OR) Class H02M 3/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12021738 | Froese et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| INVENTOR(S) | Edwin L. Froese (Burnaby, Canada); Robert L. Alverson (Seattle, Washington); Konstantinos Fragkiadakis (Bristol, United Kingdom) |
| ABSTRACT | Systems and methods are provided for managing multicast data transmission in a network having a plurality of switches arranged in a Dragonfly network topology, including: receiving a multicast transmission at an edge port of a switch and identifying the transmission as a network multicast transmission; creating an entry in a multicast table within the switch; routing the multicast transmission across the network to a plurality of destinations via a plurality of links, wherein at each of the links the multicast table is referenced to determine to which ports the multicast transmission should be forwarded; and changing, when necessary, the virtual channel used by each copy of the multicast transmission as the copy progresses through the network. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/594686 |
| ART UNIT | 2465 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) G06F 9/546 (20130101) G06F 12/0862 (20130101) G06F 12/1036 (20130101) G06F 12/1063 (20130101) G06F 13/14 (20130101) G06F 13/16 (20130101) G06F 13/385 (20130101) G06F 13/1642 (20130101) G06F 13/1673 (20130101) G06F 13/1689 (20130101) G06F 13/4022 (20130101) G06F 13/4068 (20130101) G06F 13/4221 (20130101) G06F 15/17331 (20130101) G06F 2212/50 (20130101) G06F 2213/0026 (20130101) G06F 2213/3808 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0083 (20130101) H04L 43/10 (20130101) H04L 43/0876 (20130101) H04L 45/02 (20130101) H04L 45/16 (20130101) H04L 45/20 (20130101) H04L 45/021 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/028 (20130101) H04L 45/28 (20130101) Original (OR) Class H04L 45/38 (20130101) H04L 45/42 (20130101) H04L 45/46 (20130101) H04L 45/70 (20130101) H04L 45/122 (20130101) H04L 45/123 (20130101) H04L 45/125 (20130101) H04L 45/566 (20130101) H04L 45/745 (20130101) H04L 45/7453 (20130101) H04L 47/11 (20130101) H04L 47/12 (20130101) H04L 47/18 (20130101) H04L 47/20 (20130101) H04L 47/22 (20130101) H04L 47/24 (20130101) H04L 47/30 (20130101) H04L 47/32 (20130101) H04L 47/34 (20130101) H04L 47/39 (20130101) H04L 47/52 (20130101) H04L 47/76 (20130101) H04L 47/80 (20130101) H04L 47/122 (20130101) H04L 47/323 (20130101) H04L 47/621 (20130101) H04L 47/626 (20130101) H04L 47/629 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) H04L 47/2466 (20130101) H04L 47/2483 (20130101) H04L 47/6235 (20130101) H04L 47/6275 (20130101) H04L 49/15 (20130101) H04L 49/30 (20130101) H04L 49/90 (20130101) H04L 49/101 (20130101) H04L 49/3009 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) H04L 49/9005 (20130101) H04L 49/9021 (20130101) H04L 49/9036 (20130101) H04L 49/9047 (20130101) H04L 67/1097 (20130101) H04L 69/22 (20130101) H04L 69/28 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12022610 | Nicholas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | Jason Dale Nicholas (Okemos, Michigan); Quan Zhou (Farmington Hills, Michigan); Thomas Rector Bieler (East Lansing, Michigan) |
| ABSTRACT | The disclosure generally relates to a method of creating patterned metallic circuits (e.g., silver circuits) on a substrate (e.g., a ceramic substrate). A porous metal interlayer (e.g., porous nickel) is applied to the substrate to improve wetting and adhesion of the patterned metal circuit material to the substrate. The substrate is heated to a temperature sufficient to melt the patterned metal circuit material but not the porous metal interlayer. Spreading of molten metal circuit material on the substrate is controlled by the porous metal interlayer, which can itself be patterned, such as having a defined circuit pattern. Thick-film silver or other metal circuits can be custom designed in complicated shapes for high temperature/high power applications. The materials designated for the circuit design allows for a low-cost method of generating silver circuits other metal circuits on a ceramic substrate. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 17/668660 |
| ART UNIT | RD00 — Electrical Circuits and Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0306 (20130101) Original (OR) Class H05K 3/22 (20130101) H05K 3/1208 (20130101) H05K 3/3478 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12022747 | Kutsaev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RadiaBeam Technologies, LLC (Santa Monica, California) |
| ASSIGNEE(S) | RadiaBeam Technologies, LLC (Santa Monica, California) |
| INVENTOR(S) | Sergey Kutsaev (Santa Monica, California); Ronald Agustsson (Venice, California); Kirill Taletski (Santa Monica, California) |
| ABSTRACT | Embodiments disclosed herein include a resonator for use in quantum computing. The resonator can include a housing that is disposed along a resonator axis. The housing can have a first portion extending from a housing distal end to near a qubit location and a second portion extending from near the qubit location to a housing proximal end. The housing can define a cavity extending from a cavity proximal end to a cavity distal end along a portion of the resonator axis. The housing can include a protrusion extending axially from the housing distal end along the resonator axis to near the qubit location. A proximal portion of the protrusion can include a tapered portion. The resonator can include a qubit extending into the cavity at the qubit location. |
| FILED | Wednesday, April 22, 2020 |
| APPL NO | 17/605915 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/40 (20220101) Electric solid-state devices not otherwise provided for H10N 60/12 (20230201) H10N 60/805 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12017771 | Turner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Travis L Turner (Yorktown, Virginia); Scott E Brynildsen (Yorktown, Virginia); John W. Mulvaney (Yorktown, Virginia); Albert R. Allen (Yorktown, Virginia); David P Lockard (Hampton, Virginia); Craig L. Streett (Fairfax, Virginia); Mehdi R Khorrami (Norfolk, Virginia) |
| ABSTRACT | Methods, systems and devices of the various embodiments may provide slat-cove fillers configured to reduce leading-edge slat noise on aircraft, such as transport aircraft. |
| FILED | Monday, April 05, 2021 |
| APPL NO | 17/222604 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 9/02 (20130101) B64C 9/08 (20130101) B64C 9/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018892 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Weibo Chen (Pasadena, California); Benjamin I. Furst (Pasadena, California); Scott N. Roberts (Altadena, California) |
| ABSTRACT | Systems and methods for thermal management using separable heat pipes and methods of manufacture thereof. Various embodiments provide a porous insert that can be used to join or connect heat pipes. Further embodiments provide thermal management systems that are modular, expandable, reparable, by allowing for joining of evaporators, condensers, and adiabatic sections via porous inserts. Various embodiments allow for two-phase thermal management systems, where liquid and gaseous phases can be transported simultaneously. Certain embodiments incorporate heat generating components with embedded evaporators and/or condensers. Many embodiments are additively manufactured, including via 3D printing. |
| FILED | Tuesday, November 02, 2021 |
| APPL NO | 17/453332 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/04 (20130101) F28D 15/0241 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019004 | Bencic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Timothy J. Bencic (Highland Heights, Ohio); David P. Rohler (Shaker Heights, Ohio); Amy F. Fagan (Fairview Park, Ohio); Steven H. Izen (Shaker Heights, Ohio); Arjun K. Maniyedath (Beachwood, Ohio) |
| ASSIGNEE(S) | PLEXAR ASSOCIATES, INC. (Shakers Hts, Ohio) |
| INVENTOR(S) | Timothy J. Bencic (Highland Heights, Ohio); David P. Rohler (Shaker Heights, Ohio); Amy F. Fagan (Fairview Park, Ohio); Steven H. Izen (Shaker Heights, Ohio); Arjun K. Maniyedath (Beachwood, Ohio) |
| ABSTRACT | A tomography duct for wind tunnels includes a plurality of light sources and sensors displaced around a support structure. The light sources are cycled and sensor measurements are made from sensors opposite the light sources. Tomographic algorithms are used to determine an extinction map from the sensor measurements. The extinction map provides details about particles in a cross-section of the air flow through the tomography duct. |
| FILED | Monday, March 14, 2022 |
| APPL NO | 17/693998 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/06 (20130101) Original (OR) Class G01N 33/0009 (20130101) G01N 33/0031 (20130101) G01N 33/0036 (20130101) G01N 2015/0026 (20130101) G01N 2015/0046 (20130101) G01N 2015/0693 (20130101) G01N 2033/1873 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019050 | Bingham et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Arlington, Virginia) |
| INVENTOR(S) | Jill P. Bingham (Seattle, Washington); Barry A. Fetzer (Renton, Washington); Gary E. Georgeson (Tacoma, Washington); Samuel R. Goertz (Issaquah, Washington) |
| ABSTRACT | A system for inspecting a structure includes a laser ultrasound device configured to direct laser light onto a surface of the structure that generates ultrasonic waves within the structure and to generate an array of ultrasound data representative of the ultrasonic waves. The system includes a robotic arm configured to move the laser light across the surface. The system includes a multiplex controller configured to trigger generation of the ultrasonic waves within the structure at an inspection location and to receive the array of ultrasound data for the inspection location. The system includes a computer system that includes a motion-control module configured to control movement of the laser light relative to the surface of the structure, a motion-tracking module configured determine when the laser light is at the inspection location, and an inspection module configured to process the array of ultrasound data to inspect the structure at the inspection location. |
| FILED | Friday, January 14, 2022 |
| APPL NO | 17/575777 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1605 (20130101) B25J 9/1664 (20130101) B25J 9/1692 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/04 (20130101) G01N 29/225 (20130101) G01N 29/265 (20130101) G01N 29/2418 (20130101) Original (OR) Class G01N 35/0099 (20130101) G01N 2291/103 (20130101) G01N 2291/0231 (20130101) G01N 2291/2694 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/40613 (20130101) G05B 2219/49007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12022172 | Borg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Stephen E. Borg (Williamsburg, Virginia); Hyun Jung Kim (Yorktown, Virginia) |
| ABSTRACT | A multi-spectral imaging system utilizing tunable optics is disclosed. Various disclosed systems include a tunable optical filter coupled to a broadband imaging system. The tunable optical filter allows discrete infrared wavelengths to pass to the broadband imaging system so that monochromatic infrared images of a scene may be captured. An image processing system may process selected monochromatic infrared images by using a ratio technique to generate an emissivity-independent thermal image of the scene. The tunable optical filter may also be used to adjust a quality factor and control an amount of radiated energy that is passed to an image sensor of the broadband imaging system thereby acting as an aperture to account for both low and high radiance portions of the scene. |
| FILED | Tuesday, April 19, 2022 |
| APPL NO | 17/723675 |
| ART UNIT | 2639 — Computer Networks |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/0859 (20130101) G01J 2005/0077 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/213 (20210101) Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 5/92 (20240101) G06T 2207/10048 (20130101) G06T 2207/20208 (20130101) G06T 2207/20221 (20130101) Pictorial Communication, e.g Television H04N 23/11 (20230101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 12016336 | Bowden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (lowa City, Iowa) |
| INVENTOR(S) | Ned B. Bowden (Iowa City, Iowa); Justin M. Carter (Iowa City, Iowa); Eric M. Brown (Iowa City, Iowa); Nimesh Ranasinghe (Iowa, Iowa); Arjun Paudel (Iowa City, Iowa); Erin E. Irish (Iowa City, Iowa) |
| ABSTRACT | The invention provides a compound of formula I: wherein X, Y, Z, R1, R2, and X+ have any of the values described in the specification. The compounds are useful to increase plant growth and/or to increase harvest yield. |
| FILED | Tuesday, February 28, 2023 |
| APPL NO | 18/115700 |
| ART UNIT | 1699 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 57/12 (20130101) Original (OR) Class A01N 57/16 (20130101) A01N 59/02 (20130101) Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 21/00 (20210801) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/06 (20130101) C07F 9/6578 (20130101) C07F 9/657118 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018135 | Scher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Herbert B. Scher (Moraga, California); Scott Strobel (Davis, California); Tina Jeoh Zicari (Davis, California); Dana Wong (Davis, California) |
| ABSTRACT | Microencapsulation methods are provided using encapsulant, fiber or film forming compositions of a cross-linkable anionic polymer, a multivalent cation salt, a chelating agent, and a volatile base. During the formation of this composition, the generally acidic chelating agent is titrated with a volatile base to an elevated pH to improve ion-binding capability. Multivalent cations are sequestered in cation-chelate complexes. Cross-linkable polymers in this solution will remain freely dissolved until some disruption of equilibrium induces the release of the free multivalent cations from the cation-chelate complex. Vaporization of the volatile base drops the pH of the solution causing the cation-chelate complexes to dissociate and liberate multivalent cations that associate with the anionic polymer to form a cross-linked matrix. During spray-drying, the formation of a wet particle, polymer cross-linking, and particle drying occur nearly simultaneously. |
| FILED | Wednesday, June 02, 2021 |
| APPL NO | 17/336766 |
| ART UNIT | 1754 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/14 (20130101) B01J 13/043 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) Original (OR) Class C08J 2305/04 (20130101) C08J 2305/08 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/16 (20130101) C08K 3/28 (20130101) C08K 5/095 (20130101) C08K 5/5357 (20130101) C08K 2003/162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018254 | Raman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Srivatsan Raman (Middleton, Wisconsin); Phil Huss (Madison, Wisconsin) |
| ABSTRACT | Described herein is a method of preparing an unbiased library of phage variants, comprising (a) preparing a population of “acceptor phage”; (b) removing an endogenous target gene and inserting gene variants into the acceptor phage genomes; (c) enriching the recombined phages; and (d) expressing the library for selection. The acceptor phage is a lytic phage comprising a synthetic genome wherein the target gene of interest is flanked by recombinase sites. The acceptor phage infects a first host bacteria expressing a recombination plasmid facilitating recombination. The phages then infect a second host bacteria expressing a counterselection system that accumulates recombined phage variants and selecting against non-recombined phages. The accumulated phage variants infect a third host bacteria. The phage library may then be sequenced and characterized. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/386176 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/102 (20130101) C12N 15/1093 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2795/10052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12018270 | Hewezi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| INVENTOR(S) | Tarek Abdelfattah Hewezi (Knoxville, Tennessee); Sarbottam Piya (Knoxville, Tennessee) |
| ABSTRACT | The invention relates to genes which may be utilized to induce resistance to soybean cyst nematode (SCN) and/or other abiotic or biotic stresses. More specifically the present disclosure provides genes that, when inactivated and/or overexpressed (for example, overexpression of genes encoding kinase-dead mutants) in a plant, particularly, a soybean plant, can confer upon the plant resistance to SCN and/or other abiotic or biotic stresses. Methods of using these genes to obtain plants, particularly soybean plants, that are resistant to SCN and/or other abiotic or biotic stresses are also provided. |
| FILED | Monday, April 12, 2021 |
| APPL NO | 17/227472 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8285 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) C12Q 2600/13 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 12016880 | Roth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Center (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Center (Seattle, Washington) |
| INVENTOR(S) | Mark B. Roth (Seattle, Washington); Michael L. Morrison (Seattle, Washington); Akiko Iwata (Seattle, Washington) |
| ABSTRACT | The present invention relates to the use of halogen compounds, including iodide, and chalcogenide compounds, including iodide, sulfide and selenide, to treat and prevent diseases and injuries. The present invention further relates to compositions comprising a halogen compound and/or a chalcogenide compound, including pharmaceutical compositions, as well as methods of manufacturing such compounds and administering such compositions to subjects in need thereof. |
| FILED | Thursday, December 30, 2021 |
| APPL NO | 17/565885 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 33/00 (20130101) A61K 33/04 (20130101) A61K 33/04 (20130101) A61K 33/16 (20130101) A61K 33/16 (20130101) A61K 33/18 (20130101) Original (OR) Class A61K 33/18 (20130101) A61K 38/063 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12017187 | Qavi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arrowhead Center, Inc. (Las Cruces, New Mexico) |
| ASSIGNEE(S) | Arrowhead Center, Inc. (Las Cruces, New Mexico) |
| INVENTOR(S) | Sahar Qavi (Sugar Land, Texas); Reza Foudazi (Norman, Oklahoma); Aaron Lindsay (Saint Paul, Minnesota) |
| ABSTRACT | A method for in situ production of antimicrobial filtration membranes that uses self-assembly of surfactants such as block copolymers as a template. The mesophase structure (for example hexagonal or lamellar) can be determined, and membrane pore size can be controlled in the nanometer range, by changing the block copolymer and the amounts of the components such as the block copolymer, aqueous solution, monomer, crosslinker, and initiator. The monomer phase cures in the template and there is no need for organic solvents and coagulation bath or other post-modification. As-synthesized membranes were found to have pore sizes with a narrow size distribution in the range of 3-4 nm with a molecular weight cutoff of 1500 g/mol and displayed both excellent fouling resistance and high permeance of water, vastly outperforming a conventional NIPS UF membrane. The monomer can comprise a quaternary ammonium group so that the membrane is antibacterial. The block copolymer can comprise hydrophilic blocks which form the surfaces of the membrane pores, rendering them hydrophilic. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/903704 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/44 (20130101) Separation B01D 67/0006 (20130101) B01D 69/02 (20130101) B01D 69/125 (20130101) Original (OR) Class B01D 71/40 (20130101) B01D 71/52 (20130101) B01D 71/80 (20130101) B01D 2323/08 (20130101) B01D 2323/24 (20130101) B01D 2323/40 (20130101) B01D 2323/345 (20130101) B01D 2325/36 (20130101) B01D 2325/48 (20130101) Compositions of Macromolecular Compounds C08L 33/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12020564 | Cook |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Maxar Technologies Holdings Inc. (Westminster, Colorado) |
| ASSIGNEE(S) | MAXAR INTELLIGENCE INC. (Westminster, Colorado) |
| INVENTOR(S) | Adam Cook (Sterling, Virginia) |
| ABSTRACT | Systems and methods for detecting vehicle behavior patterns in real-time. One embodiment is a method of continuous vehicle behavior detection. The method includes receiving a vehicle behavior profile including one or more travel patterns that define a vehicle behavior, receiving track data of one or more vehicles, hashing the track data as it is received to generate hash values that uniquely identify cells that approximate locations of the one or more vehicles, and storing the hash values in a hash library. The method also includes analyzing the hash library as the hash values are stored to compare the cells with the one or more travel patterns in the vehicle behavior profile, and in response to determining a group of the cells match the one or more travel patterns, generating a message indicating the vehicle behavior is detected. |
| FILED | Wednesday, September 14, 2022 |
| APPL NO | 17/932222 |
| ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Traffic Control Systems G08G 1/0125 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 12017832 | Steed |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Darren Jay Steed (Egg Harbor Township, New Jersey) |
| ABSTRACT | The present application is directed to a packaging for a powdered explosive-detection training aid which may include first and second opposing flexible sheets heat sealed together along less than a periphery thereof and defining a storage compartment therebetween, wherein an unsealed portion of the periphery defines an opening to the storage compartment, wherein at least a portion of the first opposing flexible sheet is a semipermeable material permeable to a vapor emitted from the powdered explosive-detection training aid, with the second opposing flexible sheet being impermeable to the powdered explosive-detection training aid vapor; and a sealing member, wherein the sealing member is secured to the first opposing flexible sheet and, in a closing position, covers the semipermeable portion of the first opposing flexible sheet. |
| FILED | Thursday, September 21, 2023 |
| APPL NO | 18/371288 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 15/02 (20130101) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 33/01 (20130101) B65D 75/30 (20130101) Original (OR) Class B65D 85/70 (20130101) B65D 2565/388 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 11/132 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 8/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019205 | Remer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | James Henry Remer (Waterford Works, New Jersey) |
| ABSTRACT | Examples are directed toward systems and methods relating to security screening. For example, a screening system includes a sensor array to sense a gravitational field caused by an item, and a conveyor to convey the item through sensing positions for scanning by the sensor array. A controller acquires weight measurement information from sensor elements, and gravitational measurement information from the sensor array. The conveyor incrementally advances the item through additional sensing positions to acquire weight measurement information and gravitational measurement information. The controller performs tomographic reconstruction to generate a tomographic image of the item, using a generated weight map as a static weight input vector and using a generated mass map as a static mass input vector for the tomographic reconstruction. |
| FILED | Friday, November 24, 2023 |
| APPL NO | 18/518866 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/226 (20240101) Original (OR) Class G01V 7/04 (20130101) Image Data Processing or Generation, in General G06T 11/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 12016884 | Cooper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UNITED STATES DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Denise R. Cooper (St. Petersburg, Florida); Lisa Gould (Warwick, Rhode Island); Niketa Patel (Land O'Lakes, Florida); Mack Wu (Tampa, Florida) |
| ABSTRACT | Provided herein are exosomal compositions and exsosomal lncRNA compositions and formulations thereof. Also provided herein are methods of treating a wound in a subject in need thereof that can contain the step of administering an exosomal composition and/or exsosomal lncRNA compositions or formulation thereof to a wound in a subject in need thereof. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 16/329448 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 35/35 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0653 (20130101) C12N 5/0667 (20130101) C12N 15/113 (20130101) C12N 2310/20 (20170501) C12N 2310/111 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12016935 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yongjian Liu (Chesterfield, Missouri); Robert Gropler (St. Louis, Missouri); Steven Brody (St. Louis, Missouri); Daniel Kreisel (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Yongjian Liu (Chesterfield, Missouri); Robert Gropler (St. Louis, Missouri); Steven Brody (St. Louis, Missouri); Daniel Kreisel (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of compositions of imaging agents and methods for use in detecting, monitoring, and evaluating CCR2 associated diseases, disorders, and conditions. |
| FILED | Tuesday, August 25, 2020 |
| APPL NO | 17/001857 |
| ART UNIT | RD00 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/02 (20130101) A61K 51/08 (20130101) Original (OR) Class A61K 51/088 (20130101) A61K 51/1244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 12019172 | McLellan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Charles P. McLellan (Fairfax, Virginia); Collier C. Apgar (Washington, District of Columbia) |
| ABSTRACT | A system and method for tracking mobile devices. The system can include a data center and a plurality of mobile devices in communication with the data center via the network. Each mobile device can include at least one sensor configured to periodically generate tracking data records, a memory, and a processor in communication with the at least one sensor and the memory. The mobile devices can transmit sets of tracking data records to the data center using reduced bandwidth relative to the original records by implement compression algorithms that can include delta encoding and/or numeric base conversion of number valued fields, as well as additional compression techniques that may be reversed at the data center to reconstruct the original records or otherwise decompress the data. |
| FILED | Friday, December 11, 2020 |
| APPL NO | 17/119990 |
| ART UNIT | 2459 — Computer Networks |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/42 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/024 (20180201) H04W 4/025 (20130101) H04W 4/029 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12020198 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Anthony Cramer Jones (Brooklyn, New York); Dominic Heinrich (New York, New York); Caspar Serge Ouvaroff (New York, New York) |
| ABSTRACT | Systems and methods for an intelligent collection box are provided. Implementations of the intelligent collection box include a processor, a computer-readable data storage system storing program instructions, a weighing scale, a display, a speaker, a microphone, a network interface, and a power generator. The program instructions, when executed by the processor, cause the intelligent collection box to perform operations including identifying keywords spoken by the user. The operations also include authenticating the user using the keywords. The operations also include determining a request for delivery of an item based on the keywords. The operations also include responding to the request for delivery. The operations also include determining a weight of the item. The operations also include determining delivery options for the item using the weight and using delivery information. The operations also include determining that the item has been received by the collection box. |
| FILED | Thursday, December 21, 2017 |
| APPL NO | 15/850432 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Household or Table Equipment A47G 29/30 (20130101) A47G 29/124 (20130101) A47G 29/1207 (20130101) A47G 29/1225 (20130101) A47G 2029/1226 (20130101) A47G 2029/1228 (20130101) Electric Digital Data Processing G06F 21/32 (20130101) G06F 40/58 (20200101) G06F 40/263 (20200101) Computer Systems Based on Specific Computational Models G06N 3/006 (20130101) G06N 20/00 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/083 (20130101) Original (OR) Class G06Q 30/0283 (20130101) Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus G07B 17/00 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/08 (20130101) G10L 15/22 (20130101) G10L 17/00 (20130101) G10L 2015/088 (20130101) G10L 2015/223 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 12017276 | Hildreth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Colorado School of Mines (Golden, Colorado) |
| ASSIGNEE(S) | Colorado School of Mines (Golden, Colorado) |
| INVENTOR(S) | Owen Hildreth (Lakewood, Colorado); Meredith Heilig (Golden, Colorado); Sanaz Yazdanparast (Golden, Colorado); Subbarao Raikar (Golden, Colorado) |
| ABSTRACT | A method is provided to remove a selective amount of material from a metal component fabricated by additive manufacturing in a self-terminating manner. The method can be used to remove support structures and trapped powder from a metal component as well as to smooth surfaces of a 3D printed metal component. In some embodiments, selected surfaces of the metal component are treated to make the selected surfaces at least one of mechanically and chemically unstable. The unstable portion of the metal support can then be removed chemically, electrochemically, or through vapor-phase etching. The method can be used for processing any fluid or vapor-accessible regions and surfaces of a 3D printed metal component. |
| FILED | Thursday, March 17, 2022 |
| APPL NO | 17/697814 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/40 (20210101) B22F 10/62 (20210101) Original (OR) Class B22F 10/68 (20210101) B22F 2301/10 (20130101) B22F 2301/15 (20130101) B22F 2301/052 (20130101) B22F 2301/205 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/20 (20200101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/12 (20130101) C23F 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 12021738 | Froese et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| INVENTOR(S) | Edwin L. Froese (Burnaby, Canada); Robert L. Alverson (Seattle, Washington); Konstantinos Fragkiadakis (Bristol, United Kingdom) |
| ABSTRACT | Systems and methods are provided for managing multicast data transmission in a network having a plurality of switches arranged in a Dragonfly network topology, including: receiving a multicast transmission at an edge port of a switch and identifying the transmission as a network multicast transmission; creating an entry in a multicast table within the switch; routing the multicast transmission across the network to a plurality of destinations via a plurality of links, wherein at each of the links the multicast table is referenced to determine to which ports the multicast transmission should be forwarded; and changing, when necessary, the virtual channel used by each copy of the multicast transmission as the copy progresses through the network. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/594686 |
| ART UNIT | 2465 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) G06F 9/546 (20130101) G06F 12/0862 (20130101) G06F 12/1036 (20130101) G06F 12/1063 (20130101) G06F 13/14 (20130101) G06F 13/16 (20130101) G06F 13/385 (20130101) G06F 13/1642 (20130101) G06F 13/1673 (20130101) G06F 13/1689 (20130101) G06F 13/4022 (20130101) G06F 13/4068 (20130101) G06F 13/4221 (20130101) G06F 15/17331 (20130101) G06F 2212/50 (20130101) G06F 2213/0026 (20130101) G06F 2213/3808 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0083 (20130101) H04L 43/10 (20130101) H04L 43/0876 (20130101) H04L 45/02 (20130101) H04L 45/16 (20130101) H04L 45/20 (20130101) H04L 45/021 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/028 (20130101) H04L 45/28 (20130101) Original (OR) Class H04L 45/38 (20130101) H04L 45/42 (20130101) H04L 45/46 (20130101) H04L 45/70 (20130101) H04L 45/122 (20130101) H04L 45/123 (20130101) H04L 45/125 (20130101) H04L 45/566 (20130101) H04L 45/745 (20130101) H04L 45/7453 (20130101) H04L 47/11 (20130101) H04L 47/12 (20130101) H04L 47/18 (20130101) H04L 47/20 (20130101) H04L 47/22 (20130101) H04L 47/24 (20130101) H04L 47/30 (20130101) H04L 47/32 (20130101) H04L 47/34 (20130101) H04L 47/39 (20130101) H04L 47/52 (20130101) H04L 47/76 (20130101) H04L 47/80 (20130101) H04L 47/122 (20130101) H04L 47/323 (20130101) H04L 47/621 (20130101) H04L 47/626 (20130101) H04L 47/629 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) H04L 47/2466 (20130101) H04L 47/2483 (20130101) H04L 47/6235 (20130101) H04L 47/6275 (20130101) H04L 49/15 (20130101) H04L 49/30 (20130101) H04L 49/90 (20130101) H04L 49/101 (20130101) H04L 49/3009 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) H04L 49/9005 (20130101) H04L 49/9021 (20130101) H04L 49/9036 (20130101) H04L 49/9047 (20130101) H04L 67/1097 (20130101) H04L 69/22 (20130101) H04L 69/28 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 12017091 | Friedman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Integrated Sensors, LLC (Palm Beach Gardens, Florida) |
| ASSIGNEE(S) | Integrated Sensors, LLC (Palm Beach Gardens, Florida) |
| INVENTOR(S) | Peter S. Friedman (Palm Beach Gardens, Florida) |
| ABSTRACT | Embodiments are directed generally to an ionizing-radiation beamline monitoring system that includes a vacuum chamber structure with vacuum compatible flanges through which an incident ionizing-radiation beam enters the monitoring system. Embodiments further include at least one scintillator within the vacuum chamber structure that can be at least partially translated in the ionizing-radiation beam while oriented at an angle greater than 10 degrees to a normal of the incident ionizing-radiation beam, a machine vision camera coupled to a light-tight structure at atmospheric/ambient pressure that is attached to the vacuum chamber structure by a flange attached to a vacuum-tight viewport window with the camera and lens optical axis oriented at an angle of less than 80 degrees with respect to a normal of the scintillator, and at least one ultraviolet (“UV”) illumination source facing the scintillator in the ionizing-radiation beam for monitoring a scintillator stability comprising scintillator radiation damage. |
| FILED | Thursday, September 07, 2023 |
| APPL NO | 18/462606 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101) A61N 5/1045 (20130101) A61N 5/1048 (20130101) A61N 5/1049 (20130101) A61N 5/1064 (20130101) A61N 5/1067 (20130101) Original (OR) Class A61N 5/1077 (20130101) A61N 2005/1059 (20130101) A61N 2005/1087 (20130101) Measurement of Nuclear or X-radiation G01T 1/29 (20130101) G01T 1/40 (20130101) G01T 1/1612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 12017102 | Hansson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alden Research Laboratory, Inc. (Holden, Massachusetts) |
| ASSIGNEE(S) | Alden Research Laboratory, Inc. (Holden, Massachusetts) |
| INVENTOR(S) | James B. Hansson (Holden, Massachusetts); Kimbal A. Hall (Princeton, Massachusetts); Daniel Bateman (Rutland, Massachusetts); David C. White (Providence, Rhode Island) |
| ABSTRACT | A nozzle for dispensing a fluid having a barrel having a proximal end and a distal end, the barrel having a passage defined by a first internal surface extending between the distal end and the proximal end, and an orifice defined by a second internal surface at the distal end of the barrel, a stem located at least partially in the barrel, the barrel is movable in relation to the stem to switch between a low pressure mode and a high pressure mode, a shaper located around an outer surface of the distal end of the barrel, the shaper being movable in relation to the barrel to switch between a low pressure fog mode and a low pressure stream mode. The nozzle is configured to dispense the fluid in a straight stream or fog in both the low pressure mode and the ultra-high pressure mode. The orifice is also configured to provide flushing capability for the ultra-high pressure mode while operating in the low pressure mode. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/080220 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Fire-fighting A62C 31/03 (20130101) Original (OR) Class Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/30 (20130101) B05B 1/34 (20130101) B05B 1/3033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019106 | Allwine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott F. Allwine (Leesburg, Virginia); Sunny Bagga (Corona, California); Brian J. Cadwell (Pasadena, Maryland); Shaun Mark Goodwin (East New Market, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Scott F. Allwine (Leesburg, Virginia); Sunny Bagga (Corona, California); Brian J. Cadwell (Pasadena, Maryland); Shaun Mark Goodwin (East New Market, Maryland) |
| ABSTRACT | This disclosure relates to systems and methods for measuring impedance characteristics of a cryogenic device under test (DUT). A channel select circuit can be configured in a first state to electrically isolate a channel output circuit from the cryogenic DUT and in a second state to electrically couple the channel output circuit to the cryogenic DUT, and at least one resistor can be positioned along a transmission path that couples a pattern generator circuit to a channel output circuit that includes the channel select circuit. A controller can be configured to cause respective test current signals to be provided along the transmission path when the channel select circuit is in respective first and second states to establish respective first and second voltages across the at least one resistor, determine first and second impedance characteristics of the transmission path for determining an impedance of the cryogenic DUT. |
| FILED | Thursday, June 02, 2022 |
| APPL NO | 17/830665 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 27/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12019230 | Rines et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Nathan E. Rines (Hollis, New Hampshire); Heather L. Keegan (Bedford, New Hampshire); Kevin A. LaRochelle (Goffstown, New Hampshire); Paul F. Messier (Brookline, New Hampshire); Stephen J. Pond (Ayer, Massachusetts); Michael J. Powers (Amherst, New Hampshire); Glen A. Rines (Hollis, New Hampshire); Donald K. Smith (Rye, New Hampshire) |
| ABSTRACT | A system and method are disclosed for a precision variable-focus telescope that includes a telescope housing containing an optical system; a gap pad including a first side and a second side, wherein the first side of the gap pad is attached to the telescope housing; a heat spreader including a first side and a second side, wherein the heat spreader is contiguous with the telescope housing and wherein the second side of the heat spreader is attached to the second side of the gap pad; a temperature-sensing device connected to the first side of the heat spreader; and an electric-film heater including a first side and a second side, wherein the second side of the electric-film heater is attached to the first side of the heat spreader. |
| FILED | Monday, June 29, 2020 |
| APPL NO | 16/915386 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 7/028 (20130101) G02B 23/06 (20130101) Original (OR) Class G02B 23/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12022608 | Duan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northrop Grumman Systems Corporation (Falls Church, Virginia) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Dah-Weih Duan (Torrance, California); Elizabeth T. Kunkee (Manhattan Beach, California); Martin E. Roden (Long Beach, California); Laura M. Woo (Rossmoor, California) |
| ABSTRACT | A microelectronics H-frame device comprising an RF crossover includes: a stack of two or more substrates, wherein a bottom surface of a top substrate comprises top substrate bottom metallization, and wherein a top surface of a bottom substrate comprises bottom substrate top metallization, wherein the top substrate bottom metallization and the bottom substrate top metallization form a ground plane that provides isolation to allow a first signal line to traverse one or more of the top substrate and the bottom substrate without being disturbed by a second signal line traversing one or more of the top substrate and the bottom substrate at a non-zero angle relative to the first signal line, at least one of the first signal line and the second signal line passing to a second level with the protection of the ground plane, thereby providing isolation from the other signal line. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/219103 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/04 (20130101) H01L 23/66 (20130101) H01L 23/528 (20130101) H01L 23/5221 (20130101) H01L 23/5226 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/08 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0237 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 25, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
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FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240625.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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