FedInvent™ Patents
Patent Details for Tuesday, July 09, 2024
This page was updated on Wednesday, July 10, 2024 at 08:22 PM GMT
Department of Health and Human Services (HHS)
| US 12029200 | Rinberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Dmitry Rinberg (Yonkers, New York); Hirofumi Nakayama (Yokohama, Japan) |
| ABSTRACT | A method of training a rodent to identify pairs of same or different odors, whereby the rodent learns the rule irrespective of the particular odors. Once trained, the rodent can be used to measure perceptual odor similarities between members of pairs of odors, which odors may be unrelated to the odors the rodent was trained on. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/906572 |
| ART UNIT | 2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 15/00 (20130101) A01K 15/02 (20130101) Original (OR) Class A01K 2227/105 (20130101) A01K 2267/0356 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029490 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Wei Zhang (Ann Arbor, Michigan); Xueding Wang (Ann Arbor, Michigan); Yannis Paulus (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to systems for low-energy (e.g., 1.0 nJ-7.0 nJ) photoacoustic microscopy and methods for employing such systems. In certain embodiments, such systems employ a low-energy nanosecond pulsed laser beam (NPLB), at least two amplifiers, and a data acquisition system with at least three channels to generate at least three digital signals (e.g., which are averaged and normalized to the energy of the NPLB). In other embodiments, provided herein are systems for combined use of photoacoustic microscopy, dye-based microscopy (e.g., with fluorescein), and optical coherence tomography. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/320755 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/13 (20130101) Original (OR) Class A61B 3/102 (20130101) A61B 5/0095 (20130101) Optical Elements, Systems, or Apparatus G02B 27/141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029492 | Larin et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Kirill V. Larin (Friendswood, Texas); Manmohan Singh (Houston, Texas); Jiasong Li (Pearland, Texas); Zhaolong Han (Shanghai, China PRC); Michael D. Twa (Birmingham, Alabama) |
| ABSTRACT | Provided herein are systems and methods to measure the intraocular pressure, ocular tissue geometry and the biomechanical properties of an ocular tissue, such as an eye-globe or cornea, in one instrument. The system is an optical coherence tomography subsystem and an applanation tonometer subsystem housed as one instrument and interfaced with a computer for at least data processing and image display. The system utilizes an air-puff and a focused micro air-pulse to induce deformation and applanation and displacement in the ocular tissue. Pressure profiles of the air puff with applanation times are utilized to measure intraocular pressure. Temporal profiles of displacement and/or spatio-temporal profiles of a displacement-generated elastic wave are analyzed to calculate biomechanical properties. |
| FILED | Thursday, December 01, 2022 |
| APPL NO | 18/072838 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/18 (20130101) A61B 3/102 (20130101) A61B 3/107 (20130101) A61B 3/165 (20130101) Original (OR) Class A61B 5/0066 (20130101) A61B 5/7246 (20130101) A61B 5/7289 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029501 | Tao et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Yuankai Tao (Nashville, Tennessee); Mohamed T. El-Haddad (Nashville, Tennessee) |
| ABSTRACT | Systems and methods for image-based guidance using automated instrument tracking. An en face image frame, generated from en face image data captured by a first imaging system (e.g., an SER imaging system), is analyzed to determine a location of an instrument in the first imaging plane. A control signal is then generated for the movement stage to control the scanning movement of a depth-based imaging system (e.g., an OCT imaging system) based on the determined location of the instrument. In some implementations, a trained neural-network is used to determine the location of the instrument based on the en face image frame and, in some implementations, the control signal adjusts the speed of the scanning movement to capture image data at a higher density7 at areas corresponding to the determined location of the instrument. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 17/421558 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/20 (20160201) Original (OR) Class A61B 2034/2065 (20160201) A61B 2090/373 (20160201) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02091 (20130101) Image Data Processing or Generation, in General G06T 3/40 (20130101) G06T 7/70 (20170101) G06T 2207/10028 (20130101) G06T 2207/10101 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029548 | Linnes et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jacqueline C. Linnes (West Lafayette, Indiana); Divya Tankasala (West Lafayette, Indiana); Shubhankar S. Takle (West Lafayette, Indiana); Orlando S. Hoilett (West Lafayette, Indiana); Gabriel P. Ng (West Lafayette, Indiana); Michael S. Smith (West Lafayette, Indiana) |
| ABSTRACT | The present disclosure relates to a novel device for selective collection and condensation of an exhaled breath, and the method of using the novel device. The novel device is portable and capable of collecting and condensing reproducible volumes of exhaled breath under about 10 minutes by using a unique temperature-based algorithm. |
| FILED | Tuesday, June 18, 2019 |
| APPL NO | 17/251254 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/082 (20130101) A61B 5/097 (20130101) Original (OR) Class A61B 5/14532 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029594 | Manor et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (La Jolla, California) |
| ASSIGNEE(S) | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES, A CORPORATION OF CALIFORNIA (La Jolla, California) |
| INVENTOR(S) | Uri Manor (La Jolla, California); Linjing Fang (La Jolla, California) |
| ABSTRACT | A method to, is provided for collecting an image from a sample. The method includes selecting a radiation level for a first probe to meet a desired radiation dosage, and providing, with the first probe, a radiation at a selected point within a region of the sample. The method includes identifying a second selected point within the region of the sample based on a down sampling scheme, and providing a second radiation amount at the second selected point within the region of the sample. The method also includes interpolating a first datum and a second datum based on an up sampling scheme to obtain a plurality of data, and forming an image of the region of the sample with the plurality of data. A system to perform the above method and including the first probe is also provided. |
| FILED | Wednesday, August 21, 2019 |
| APPL NO | 17/269986 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/542 (20130101) A61B 6/4035 (20130101) A61B 6/4258 (20130101) Original (OR) Class A61B 6/5282 (20130101) A61B 6/5288 (20130101) Image Data Processing or Generation, in General G06T 11/00 (20130101) G06T 2210/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029636 | Papas |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Klearchos K. Papas (Tucson, Arizona) |
| ABSTRACT | Systems featuring two or more encapsulation devices stacked together. The encapsulation devices house cells, such as but not limited to islet cells or stem cell derived beta cells or the like. e.g., for regulating blood glucose, or other cells or spheroids that can produce and release a therapeutic agent that is useful in the body, etc. The system may feature oxygen delivery, or in some cases no exogenous oxygen is delivered and vascularization of the device can help provide oxygen and other needed nutrient to the cells. The system of the present invention may be used in conjunction with other therapies such as an artificial pancreas. Stacking the devices with blood vessel formation around and in between them may allow for a decrease in the footprint that would be needed for implantation. |
| FILED | Friday, September 02, 2022 |
| APPL NO | 17/902689 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/022 (20130101) Original (OR) Class A61F 2220/0075 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/225 (20130101) A61L 27/227 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029648 | Havel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Muffin Incorporated (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | William J. Havel (West Lafayette, Indiana); Jeremy T. Newkirk (West Lafayette, Indiana); Rita Hadley (Otterbein, Indiana); Yun Zhou (Eden Prairie, Minnesota) |
| ABSTRACT | Among other things, there are disclosed embodiments of devices used for minimally-invasive treatments, such as treatment of mitral valves. In a system for placing an annuloplasty belt around the heart, embodiments for tensioning a suture associated with the belt are provided, as are embodiments of a suture lock for holding the suture with the applied tension. A delivery device that permits placement and tensioning of such a belt and activation of the suture lock in one procedure is also disclosed. Methods for making and using these features are also disclosed. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/097623 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/04 (20130101) A61B 17/0485 (20130101) A61B 2017/0409 (20130101) A61B 2017/0488 (20130101) A61B 2017/0496 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2466 (20130101) Original (OR) Class A61F 2220/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029686 | Mbagwu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The United States of America as represented by The Department Of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Michael Mbagwu (Mountain View, California); David Buickians (Glendale, California); David Myung (Saratoga, California) |
| ABSTRACT | Precise concentric, symmetric, and repeatable circular scoring (cutting) of Descemet's membrane is made possible by a handheld surgical ophthalmic device. The precision of the cut is provided by a stabilizing point on a stabilizing arm as well the anchoring insertion point at the limbus. Stabilization through the insertion point and the stabilizing arm provides a two-point fixation thereby establishing a cutting plane. The cutting plane allows for precise depth of cut whereas the rotating blade's consistent radius allows for circularity of the cut. The stabilization arm fixates on tissue, and is then removed when the procedure is completed. Consistent torque and contact pressure of the cutting blade is provided through rotational control via the depression of a button on a handle thereby removing the need to “free-hand” the desemetorhexis. |
| FILED | Tuesday, March 15, 2022 |
| APPL NO | 17/695484 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0133 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029713 | Cohen |
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| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Akiva S. Cohen (Bala Cynwyd, Pennsylvania) |
| ABSTRACT | Compositions and methods are provided for the alleviation of pathology induced by traumatic brain injury. |
| FILED | Monday, February 13, 2023 |
| APPL NO | 18/109037 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/198 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029717 | Massague et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Joan Massague (New York, New York); Adrienne Boire (New York, New York); Qing Chen (Palisades Park, New Jersey) |
| ABSTRACT | The present invention relates to methods for treating brain metastasis by inhibiting gap junction functionality. It is based, at least in part, on the discovery that cancer cells expressing Protocadherin 7 and Connexin 43 form gap junctions with astrocytes that promote the growth of brain metastases, and that inhibition of Protocadherin 7 and/or Connexin 43 expression in cancer cells reduce progression of brain metastases. It is further based on the discovery that treatment with gap junction inhibitors tonabersat and meclofenamate inhibited progression of brain metastatic lesions and enhanced the anti-cancer activity of the conventional chemotherapeutic agent, carboplatin. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 17/345572 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/196 (20130101) A61K 31/196 (20130101) A61K 31/282 (20130101) A61K 31/352 (20130101) Original (OR) Class A61K 31/352 (20130101) A61K 31/555 (20130101) A61K 31/555 (20130101) A61K 31/7105 (20130101) A61K 31/7105 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 2333/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029721 | Pappas |
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| FUNDED BY |
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| APPLICANT(S) | Schedule 1 Therapeutics, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | Schedule 1 Therapeutics, Inc. (Chicago, Illinois) |
| INVENTOR(S) | George D. Pappas (Chicago, Illinois) |
| ABSTRACT | The present disclosure is related to the use of compositions and their use in reducing and treating pain. |
| FILED | Friday, June 09, 2023 |
| APPL NO | 18/208017 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/352 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029728 | Rogelj et al. |
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| FUNDED BY |
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| APPLICANT(S) | New Mexico Tech University Research Park Corporation (Socorro, New Mexico) |
| ASSIGNEE(S) | New Mexico Tech University Research Park Corporation (Socorro, New Mexico) |
| INVENTOR(S) | Snezna Rogelj (Socorro, New Mexico); Danielle Nicole Turner (Socorro, New Mexico); Ivy Hurwitz (Socorro, New Mexico); Alexander Aksenov (Socorro, New Mexico) |
| ABSTRACT | The present disclosure describes a method of treating an infection, including a parasitic infection, using compounds of the invention. The compounds of the invention can selectively eradicate intracellular mammalian and human parasites. |
| FILED | Tuesday, October 29, 2019 |
| APPL NO | 17/286599 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/405 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029732 | Terzian et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Tamara Terzian (Aurora, Colorado); Neil Box (Aurora, Colorado) |
| ABSTRACT | Disclosed herein are compositions, methods, and systems useful in the prevention, management, or treatment of various conditions associated the lymphatic vasculature, including, but not limited to lymphedema. The disclosed methods and compositions are useful in reducing the activity of p53 in a subject at risk for or suffering from a disease or condition associated with lymphatic vasculature, including adults, children, infants, and embryos. Reduction in p53 activity may be achieve through reduction in one or more of p53 gene expression, p53 transcriptional activity, p53 DNA-binding affinity, etc. In many embodiments, the disease or condition is lymphedema, for example lymphedema associated with Milroy's disease, Klippel-Trenaunay and Cloves Syndromes. In many embodiments, treatment may involve administering a compound or pharmaceutically acceptable salt thereof to a subject in need thereof, exemplary compounds include, anti-p53 compounds, PFT, and PFT-β. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 17/604858 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/428 (20130101) Original (OR) Class A61K 31/429 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029745 | Christofidou-Solomidou et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Melpo Christofidou-Solomidou (Eagleville, Pennsylvania); Angela Haczku (Davis, California) |
| ABSTRACT | The invention provides compositions and methods for treating asthma in a subject in need thereof comprising administering chemically synthesized secoisolaricirecinol diglucoside (SDG), and in particular, a racemic mixture of the SDG (LGM2605), stereoisomers thereof, metabolites thereof, and analogs thereof. Also provided are methods for treating or preventing ozone-induced damage in a subject in need thereof. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 17/549584 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/7032 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) A61P 39/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029759 | Segal et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Benjamin M. Segal (Ann Arbor, Michigan); Andrew Sas (Ann Arbor, Michigan); Kevin Carbajal (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein are compositions and methods for treating neurological disorders. In particular, provided herein are neutrophils that rescue damaged neurons, methods of making such neutrophils, and methods of promoting generation of such neutrophils in vivo. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/965816 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0642 (20130101) C12N 2500/34 (20130101) C12N 2501/13 (20130101) C12N 2501/15 (20130101) C12N 2501/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029760 | Zhao et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Yangbing Zhao (Lumberton, New Jersey); Jiangtao Ren (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention includes compositions and methods for modifying primary T cells. In one aspect, the invention comprises administering to a cell a stem-loop Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) RNA (st-crRNA) and a Cpf1 enzyme. |
| FILED | Wednesday, May 02, 2018 |
| APPL NO | 16/609628 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 2039/5158 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/117 (20130101) C12N 2310/20 (20170501) C12N 2310/122 (20130101) C12N 2310/315 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029777 | Lucas et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Alexandra Lucas (Tempe, Arizona); Jordan Yaron (Scottsdale, Arizona); Efrem Lim (Phoenix, Arizona) |
| ABSTRACT | Disclosed herein is are methods of preventing, reducing or inhibiting a viral or immune disorder, comprising administering to a subject at risk or that has acquired a viral or immune disorder an effective amount of a composition comprising a polypeptide derived from a reactive center loop of a serine protease inhibitor or a biologically active variant thereof, wherein the subject has not been administered antibiotics within at least one day of administering the composition. Also disclosed are compositions and kits for preventing, reducing or inhibiting a viral or immune disorder. |
| FILED | Monday, January 13, 2020 |
| APPL NO | 17/422718 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/005 (20130101) A61K 38/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029790 | Dong et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Yizhou Dong (Dublin, Ohio); Xinfu Zhang (Columbus, Ohio) |
| ABSTRACT | The present disclosure relates to biomimetic nanomaterials, compounds, compositions, and methods for delivery of therapeutic, diagnostic, or prophylactic agents (for example, a nucleic acid). |
| FILED | Tuesday, July 31, 2018 |
| APPL NO | 16/635786 |
| ART UNIT | 1699 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 47/543 (20170801) Original (OR) Class A61K 47/544 (20170801) A61K 47/549 (20170801) A61K 47/551 (20170801) A61K 47/6929 (20170801) Acyclic or Carbocyclic Compounds C07C 235/12 (20130101) C07C 401/00 (20130101) C07C 403/12 (20130101) C07C 2601/14 (20170501) C07C 2601/16 (20170501) C07C 2602/14 (20170501) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/09 (20130101) C07F 9/091 (20130101) C07F 9/650952 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029793 | Reshetnyak et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Rhode Island Board of Trustees (Kingston, Rhode Island); Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut); University of Rhode Island Board of Trustees (Kingston, Rhode Island) |
| INVENTOR(S) | Yana K. Reshetnyak (Saunderstown, Rhode Island); Oleg A. Andreev (Saunderstown, Rhode Island); Anna Moshnikova (Warwick, Rhode Island); Donald M. Engelman (New Haven, Connecticut) |
| ABSTRACT | The invention features a composition comprising a potent cytotoxic compound and a pH low insertion peptide, where, e.g., the cytotoxic compound cannot be used alone due to a lack of targeting. The pH low insertion peptide targets cytotoxic compounds to acidic diseased tissue, translocates cytotoxic compounds across plasma membranes into the cytosols of cells in acidic diseased tissues and induces cell death predominantly in the targeted acidic diseased tissue. |
| FILED | Tuesday, January 28, 2020 |
| APPL NO | 16/774966 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0034 (20130101) A61K 31/4745 (20130101) A61K 31/5386 (20130101) A61K 31/7036 (20130101) A61K 38/12 (20130101) A61K 47/60 (20170801) A61K 47/6415 (20170801) A61K 47/6425 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029794 | de los Pinos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aura Biosciences, Inc. (Boston, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Serv. (Bethesda, Maryland) |
| ASSIGNEE(S) | Biosciences, Inc. (Boston, Massachusetts); The United States of America, as represented by the Secretary, Department of Health and Human Serv. (Bethesda, Maryland) |
| INVENTOR(S) | Elisabet de los Pinos (Brookline, Massachusetts); John Todd Schiller (Kensington, Maryland); Rhonda C. Kines (Washington, District of Columbia); John MacDougall (Hingham, Massachusetts) |
| ABSTRACT | The present disclosure is directed to methods and compositions for the diagnosis and/or treatment of tumors, such as ocular tumors, using virus-like particles conjugated to photosensitive molecules. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 17/540549 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 41/0057 (20130101) A61K 41/0071 (20130101) A61K 47/64 (20170801) A61K 47/6901 (20170801) Original (OR) Class A61K 2039/545 (20130101) A61K 2039/585 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) Peptides C07K 1/13 (20130101) C07K 14/025 (20130101) C07K 16/32 (20130101) C07K 16/084 (20130101) C07K 2317/33 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/20023 (20130101) C12N 2710/20033 (20130101) C12N 2710/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029798 | Zeng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Dexing Zeng (Portland, Oregon); Lingyi Sun (Pittsburgh, Pennsylvania); Yongkang Gai (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention provides a method of targeted molecular imaging and/or targeted drug delivery, wherein two components or probes each interacts with one or more biomarkers on a cell and separately interact with each other to form a stable bond, such as a stable covalent bond. In certain non-limiting embodiments, at least one of the probes is photo-triggered to allow for bonding with at least one second probe. In certain non-limiting embodiments, the cell is a tumor or cancer cell. The present invention also relates to compounds, probes, and kits for use in targeted molecular imaging and/or targeted drug delivery. |
| FILED | Friday, November 02, 2018 |
| APPL NO | 16/179785 |
| ART UNIT | RD00 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 47/6893 (20170801) A61K 51/082 (20130101) Original (OR) Class A61K 51/1027 (20130101) Heterocyclic Compounds C07D 255/02 (20130101) C07D 257/02 (20130101) Peptides C07K 7/06 (20130101) C07K 7/64 (20130101) C07K 16/30 (20130101) C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/5008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029822 | Dahlman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | James Dahlman (Atlanta, Georgia); Kalina Paunovska (Atlanta, Georgia) |
| ABSTRACT | Lipid nanoparticles and compositions thereof are disclosed herein. An exemplary nanoparticle composition includes an ionizable lipid, a phospholipid, a PEG-lipid, and a cholesterol modified with a hydroxyl group near the D-sterol ring. The disclosed nanoparticle compositions can target liver Kupffer cells and endothelial cells more preferentially than hepatocytes which should be beneficial in treating liver diseases in which dysfunctional Kupffer cells and endothelial cells are involved in disease pathogenesis. |
| FILED | Thursday, September 02, 2021 |
| APPL NO | 17/465034 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5123 (20130101) Original (OR) Class A61K 9/5146 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029829 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Jianyu Li (Verdun, Canada); Adam D. Celiz (Braintree, United Kingdom); David J. Mooney (Sudbury, Massachusetts) |
| ABSTRACT | The present invention is directed to a biocompatible adhesive system comprising a) a hydrogel comprising a first polymer network and a second polymer network, wherein the first polymer network comprises covalent crosslinks and the second polymer network comprises ionic crosslinks; b) a high density primary amine polymer; and c) a coupling agent. The present invention also provides methods preparing and using the biocompatible adhesive system. |
| FILED | Wednesday, March 22, 2017 |
| APPL NO | 16/086631 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/7046 (20130101) A61K 9/7061 (20130101) A61K 9/7069 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/0015 (20130101) A61L 24/0031 (20130101) Original (OR) Class A61L 24/043 (20130101) A61L 24/043 (20130101) A61L 2400/04 (20130101) A61L 2400/06 (20130101) A61L 2420/02 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029832 | Cui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia) |
| INVENTOR(S) | Haitao Cui (Arlington, Virginia); Lijie Grace Zhang (Ashburn, Virginia); Yimin Huang (Beijing, China PRC) |
| ABSTRACT | A cardiac patch for treatment of a mammalian heart including perfusable vessels embedded integratedly between two layers of anisotropically oriented myocardial fibers. The cardiac patch is made using a dual 3D bioprinting technique using stereolithography to form an anisotropic construct and extrusion printing to form perfusion vessels. A nutrient and oxygen containing media can be provided within the perfusion vessels for growth of cells in the cardiac patch. The technique permits larger patches to be made for the treatment of cardiac damage in both small and large mammalian hearts. |
| FILED | Friday, April 10, 2020 |
| APPL NO | 16/845329 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/26 (20130101) A61L 27/367 (20130101) A61L 27/3625 (20130101) Original (OR) Class A61L 27/3808 (20130101) A61L 27/3826 (20130101) A61L 27/3834 (20130101) A61L 27/3873 (20130101) A61L 2430/20 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) B29C 64/124 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2033/08 (20130101) B29K 2089/00 (20130101) B29K 2105/0088 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7546 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029900 | Arora et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Rishi Arora (Chicago, Illinois); Alan Kadish (Evanston, Illinois); Jason Ng (Evanston, Illinois) |
| ABSTRACT | The invention relates generally to systems and devices for material delivery, energy delivery, and/or monitoring electrophysiological activity, and method of use thereof. In particular, the present invention provides devices and systems, and methods of use thereof, configured to deliver therapeutic compositions, to provide electroporation and/or sonoporation to increase therapeutic efficiency, and to monitor electrophysiological activity, for example, before and after treatment. |
| FILED | Tuesday, August 06, 2019 |
| APPL NO | 16/533265 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/20 (20130101) A61N 1/327 (20130101) Original (OR) Class A61N 1/0412 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029922 | Hachadorian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Rachael Hachadorian (Norwich, Vermont); Brian Pogue (Hanover, New Hampshire); Petr Bruza (Lebanon, New Hampshire); Lesley Jarvis (Hanover, New Hampshire) |
| ABSTRACT | A system for monitoring radiation treatment images Cherenkov emissions from tissue of a subject. A processor of the system determines densities of a surface layer of the subject from 3D images of the tissue to determine correction factors. The processor uses these factors to correct the Cherenkov images for attenuation of Cherenkov light by tissue, making them proportional to radiation dose. In embodiments, the system obtains reflectance images of the subject, determines second correction factors therefrom, and applies the second correction factors to the Cherenkov emissions images. In embodiments, the corrected images of Cherenkov emissions are compared to dose maps of a treatment plan. A method of correcting Cherenkov emissions images includes determining tissue characteristics from CT or MRI images in a surface volume where Cherenkov is expected, using; imaging Cherenkov emissions; and using the tissue characteristics to correct the images for variations in Cherenkov light propagation through the tissue. |
| FILED | Wednesday, July 15, 2020 |
| APPL NO | 17/627633 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) A61N 5/103 (20130101) A61N 5/1039 (20130101) A61N 5/1048 (20130101) A61N 5/1049 (20130101) A61N 5/1071 (20130101) Original (OR) Class A61N 2005/1055 (20130101) A61N 2005/1059 (20130101) A61N 2005/1061 (20130101) A61N 2005/1087 (20130101) A61N 2005/1089 (20130101) Measurement of Nuclear or X-radiation G01T 1/22 (20130101) G01T 1/2992 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030045 | Thomas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sequitur Health Corp. (Scottsdale, Arizona) |
| ASSIGNEE(S) | Sequitur Health Corp. (Scottsdale, Arizona) |
| INVENTOR(S) | Marylaura L. Thomas (Scottsdale, Arizona); Leslie F. Thomas (Scottsdale, Arizona); Erica S. Forzani (Phoenix, Arizona); Phuoc H. H. Duong (Phoenix, Arizona) |
| ABSTRACT | The device, e.g., sensing cartridge, includes a first member, a second member coupled to the first member, a third member coupled to the second member, and a fourth member coupled to the third member. The first member is configured to separate plasma from whole blood, where the whole blood has a cellular component with a hydrodynamic diameter greater than 0.01 μm. The second member is configured to wick the plasma from the whole blood, where the second member acts on ammonium in the plasma to shift a phase equilibrium of the ammonium to ammonia gas. The third member is configured to prevent liquid permeation produced by the shift in the phase equilibrium of the ammonium to the ammonia gas. The fourth member is configured to act on the ammonia gas. |
| FILED | Thursday, January 05, 2023 |
| APPL NO | 18/093466 |
| ART UNIT | 1796 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) Original (OR) Class B01L 2200/04 (20130101) B01L 2200/16 (20130101) B01L 2300/069 (20130101) B01L 2300/0654 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) G01N 21/31 (20130101) G01N 33/497 (20130101) G01N 33/4975 (20240501) G01N 2201/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030867 | Blagg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana); University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana); University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Brian Blagg (Notre Dame, Indiana); Sanket Mishra (Notre Dame, Indiana) |
| ABSTRACT | Described are compounds of formula (I), based on an isoquinolin-1(2H)-one backbone, that function as Hsp90β selective inhibitors. Also described are pharmaceutical compositions thereof and methods of treating cancer by administering compounds of formula (I). |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 17/055980 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030888 | Movassaghi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Mohammad Movassaghi (Lincoln, Massachusetts); Bradley L. Pentelute (Cambridge, Massachusetts); Carly Schissel (Cambridge, Massachusetts); Kyan Anthony D'Angelo (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides compounds of Formula I, methods of preparing the compounds, compositions, kits, and methods of using the compounds for treating or preventing microbial infections. |
| FILED | Thursday, December 23, 2021 |
| APPL NO | 17/561680 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) C07B 2200/07 (20130101) Heterocyclic Compounds C07D 209/86 (20130101) C07D 487/04 (20130101) Original (OR) Class C07D 487/14 (20130101) C07D 487/22 (20130101) C07D 498/22 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030892 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Eric Fischer (Chestnut Hill, Massachusetts); Alyssa Verano (Allston, Massachusetts); Zhixiang He (Brookline, Massachusetts); Guangyan Du (Jamaica Plain, Massachusetts); Katherine Donovan (Boston, Massachusetts); Radoslaw Nowak (Boston, Massachusetts); Jing Ting Christine Yuan (Brookline, Massachusetts) |
| ABSTRACT | Disclosed are degraders, pharmaceutical compositions containing them, and methods of making and using the degraders to treat diseases and disorders characterized by dysregulated or dysfunctional protein activity that can be targeted by cereblon. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 17/255750 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/545 (20170801) Heterocyclic Compounds C07D 401/04 (20130101) C07D 495/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030893 | Gibbs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Summer L. Gibbs (West Linn, Oregon); Lei G. Wang (Portland, Oregon); Connor W. Barth (Portland, Oregon) |
| ABSTRACT | Provided are near-infrared nerve-sparing fluorescent compounds, compositions comprising them, and methods of their use in medical procedures. |
| FILED | Wednesday, September 11, 2019 |
| APPL NO | 17/275608 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/0075 (20130101) Heterocyclic Compounds C07D 498/04 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030896 | Bram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| INVENTOR(S) | Richard J. Bram (Rochester, Minnesota); Anthony B. Pinkerton (Rancho Santa Fe, California); Eduard Serguienko (San Diego, California) |
| ABSTRACT | The present application provides, inter alia, a compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein Y, Ar, X1, X2, X3, R1, R2, R3, R4, R5, and R6 are as described herein. Methods of making these compounds and methods of using these compound for treating diseases such as cancer are also provided. |
| FILED | Monday, July 01, 2019 |
| APPL NO | 17/255810 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 251/66 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 403/14 (20130101) C07D 405/12 (20130101) C07D 409/12 (20130101) C07D 413/14 (20130101) C07D 487/04 (20130101) C07D 495/04 (20130101) C07D 498/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030901 | Driver et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Indianapolis, Indiana); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana); The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Tom G. Driver (Chicago, Illinois); Roberto F. Machado (Carmel, Indiana); Naijing Su (Newark, Delaware); Xinyu Guan (Chicago, Illinois); Wrickban Mazumdar (Chicago, Illinois); Kira Ratia (Chicago, Illinois); Jason Ralph Hickok (Chicago, Illinois); Angelia Denise Lockett (Indianapolis, Indiana) |
| ABSTRACT | Disclosed herein are compounds that can act as inhibitors of nicotinamide phosphoribosyltransferase (“NAMPT”), and methods for their use in treating or preventing diseases, such as pulmonary arterial hypertension (“PAH”). The compounds described herein can include compounds of Formula (II) and pharmaceutically acceptable salts thereof: wherein the substituents are as described. |
| FILED | Wednesday, November 16, 2022 |
| APPL NO | 18/056089 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 401/12 (20130101) C07D 491/056 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0816 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030928 | Palese et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| INVENTOR(S) | Peter Palese (New York, New York); Florian Krammer (New York, New York); Teddy John Wohlbold (New York, New York); Adolfo Garcia-Sastre (New York, New York) |
| ABSTRACT | Provided herein are antibodies that bind to neuraminidase (NA) of different strains of influenza B virus, host cells for producing such antibodies, and kits comprising such antibodies. Also provided herein are compositions comprising antibodies that bind to NA of different strains of influenza B virus and methods of using such antibodies to diagnose, prevent or treat influenza virus disease. |
| FILED | Wednesday, January 05, 2022 |
| APPL NO | 17/569253 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/52 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) C07K 2317/732 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030929 | Han |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Yiping Han (Paramus, New Jersey) |
| ABSTRACT | Anti-Fn amyloid-like FadA antibodies and compositions are provided and methods of treating cancers, including pancreatic and colorectal, and periodontal diseases. Methods include preventing, reducing development, or treating disease in a subject in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an agent which inhibits or blocks an amyloid-like FadA secreted from Fusobacterium nucleatum (Fn). |
| FILED | Monday, August 28, 2023 |
| APPL NO | 18/457239 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1203 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030950 | Axtell |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OKLAHOMA MEDICAL RESEARCH FOUNDATION (Oklahoma City, Oklahoma) |
| ASSIGNEE(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
| INVENTOR(S) | Robert C. Axtell (Oklahoma City, Oklahoma) |
| ABSTRACT | The present disclosure provides for the diagnosis and prediction of neuromyelitis optica (NMO) in subject. It also provides for treatment of multiple sclerosis (MS) in a subject. |
| FILED | Wednesday, September 25, 2019 |
| APPL NO | 16/582034 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 45/06 (20130101) Peptides C07K 16/2875 (20130101) C07K 16/2878 (20130101) Original (OR) Class C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/28 (20130101) G01N 2800/52 (20130101) G01N 2800/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030958 | Dinarello et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado); Konkuk University Industry Cooperation Foundation (Chungju, South Korea) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado); Konkuk University Industry Cooperation Foundation (Chungju, South Korea) |
| INVENTOR(S) | Charles A. Dinarello (Denver, Colorado); Soohyun Kim (Greenwood Village, Colorado) |
| ABSTRACT | Embodiments herein report compositions of alpha-1 antitrypsin fusion polypeptides or peptide derivatives thereof. In certain embodiments, compositions and methods relate to generating a construct of use in pharmaceutically acceptable compositions to treat a subject in need of alpha-1 antitrypsin therapy or treatment. In other embodiments, compositions and methods disclosed herein concern linking alpha-1 antitrypsin or derivative thereof to an immune fragment. |
| FILED | Friday, September 10, 2021 |
| APPL NO | 17/471466 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/57 (20130101) Peptides C07K 14/8125 (20130101) C07K 16/40 (20130101) Original (OR) Class C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030959 | Owen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Genentech, Inc. (South San Francisco, California) |
| ASSIGNEE(S) | Genentech, Inc. (South San Francisco, California) |
| INVENTOR(S) | Ryan Patrick Owen (Millbrae, California); Ahmar Iqbal (San Bruno, California); Robert A. Wood (Lutherville, Maryland) |
| ABSTRACT | The present disclosure provides methods and kits for treating or preventing an allergic reaction to a food allergen consumed by a human subject with one or more food allergies. In particular, the present disclosure provides prophylactic therapies comprising administration of an anti-IgE antibody at a specific dose to a human subject who is allergic to one or more food allergens. |
| FILED | Thursday, October 12, 2023 |
| APPL NO | 18/486053 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/08 (20180101) Peptides C07K 16/4291 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030980 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jeremiah A. Johnson (Boston, Massachusetts); Peyton Shieh (Cambridge, Massachusetts); Keith Husted (Boston, Massachusetts); Christopher M. Brown (Boston, Massachusetts); Samantha Lynn Kristufek (Lubbock, Texas) |
| ABSTRACT | The present disclosure provides compositions comprising: a) a copolymer prepared by a method comprising polymerizing in the presence of a metathesis catalyst: i) a first monomer, wherein each instance of the first monomer is independently of the formula: or salt thereof; ii) a second monomer, wherein each instance of the second monomer is independently of the formula: or a salt thereof; iii) optionally a third monomer, wherein the third monomer is different from the first monomer and the second monomer; and iv) optionally a reprocessing catalyst; and b) optionally the reprocessing catalyst; wherein the reprocessing catalyst is a Brønsted acid, Lewis acid, Brønsted base, Lewis base, or a salt thereof; provided that the composition comprises at least one of the reprocessing catalyst of iv) and the reprocessing catalyst of b). The compositions may be reprocessed (e.g., remolded) under elevated temperature and/or elevated pressure. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538098 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) Original (OR) Class C08G 61/12 (20130101) C08G 2261/70 (20130101) C08G 2261/314 (20130101) C08G 2261/418 (20130101) C08G 2261/3222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030985 | Saltzman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | W. Mark Saltzman (New Haven, Connecticut); Yuhang Jiang (New Haven, Connecticut) |
| ABSTRACT | Poly(amine-co-ester) polymers, methods of forming active agent-load polyplexes and particles therefrom, and methods of using them for delivery of nucleic acid agents with optimal uptake have been developed. Examples demonstrate critical molecular weights in combination with exposed carboxylic and/or hydroxyl groups, and methods of making. Typically, the compositions are less toxic, more efficient at drug delivery, or a combination thereof compared to a control other transfection reagents. In some embodiments, the compositions are suitable for in vivo delivery, and can be administered systemically to a subject to treat a disease or condition. |
| FILED | Friday, July 28, 2023 |
| APPL NO | 18/361630 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/595 (20170801) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/685 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031033 | Wagner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | William R. Wagner (Gibsonia, Pennsylvania); Sang Ho Ye (Cheswick, Pennsylvania); Seungil Kim (Pittsburgh, Pennsylvania); Sung Kwon Cho (Pittsburgh, Pennsylvania) |
| ABSTRACT | A zwitterionic polysiloxane polymer (e.g., a polyurethane elastomer) composition having poly(dialkylsiloxane) blocks and a zwitterionic moiety is prepared by the copolymerization of a poly(dialkylsiloxane) diol, a diisocyanate, a tertiary amine alkyl diol, and a poly(dialkylsiloxane) diamine to form a poly(urethane urea) copolymer. A substituted saturated heterocylic compound is reacted with the tertiary amine of the poly(urethane urea) copolymer to introduce a zwitterionic group into the poly(urethane urea) copolymer backbone. A polysiloxane polymer having a zwitterionic moiety is prepared by reacting a diallyl tertiary amine compound and a substituted saturated heterocylic compound to form a diallyl zwitterionic macromer and cross-linking a vinyl terminated poly(dialkylsiloxane) and the diallyl zwitterionic macromer with a curing agent to introduce a zwitterionic group into the poly(dialkylsiloxane) polymer. |
| FILED | Tuesday, August 10, 2021 |
| APPL NO | 17/398618 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/06 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/17 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031072 | Shenderova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Olga A. Shenderova (Raleigh, North Carolina); Alexander M. Zaitsev (Staten Island, New York); Nicholas A. Nunn (Raleigh, North Carolina); Marco Diego Torelli (Raleigh, North Carolina) |
| ASSIGNEE(S) | ADAMAS NANOTECHNOLOGIES INC (Raleigh, North Carolina); RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Olga A. Shenderova (Raleigh, North Carolina); Alexander M. Zaitsev (Staten Island, New York); Nicholas A. Nunn (Raleigh, North Carolina); Marco Diego Torelli (Raleigh, North Carolina) |
| ABSTRACT | A method of controlled production of luminescent diamond particles exhibiting luminescence in selected specific spectral ranges is provided. The method comprises taking diamond particles containing dopant atoms in the diamond core, irradiating the particles with high energy radiation, and annealing the irradiated diamond particles at a target temperature in the temperature range of about 1400° C.-2200° C. to form luminescent diamond particles where the specific spectral range of luminescence is controlled by the target temperature of the annealing process, the irradiation dose, and the type of dopant atoms. Duration of the annealing and the temperature ramp up and ramp down times should be short enough to minimize or prevent significant graphitization of the particles. Duration of the temperature ramp up time should be short enough to minimize formation of color centers that might form at temperatures below the target temperature. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/233843 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/28 (20170801) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/65 (20130101) Original (OR) Class Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 1/02 (20130101) C30B 29/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031126 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Andrew Vito Anzalone (Cambridge, Massachusetts); Jonathan Ma Levy (Brookline, Massachusetts); Xin Gao (Cambridge, Massachusetts); Christopher J. Podracky (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides systems, compositions, and methods for simultaneously editing both strands of a double-stranded DNA sequence at a target site to be edited. In some aspects, the systems comprise a first and second prime editor complex, wherein each of the first and second prime editor complexes comprises (1) a prime editor comprising (i) a nucleic acid programmable DNA binding protein (napDNAbp), and (ii) a polypeptide having an RNA-dependent DNA polymerase activity; and (2) a pegRNA comprising a spacer sequence, gRNA core, a DNA synthesis template, and a primer binding site, wherein the DNA synthesis template encodes a desired DNA sequence or a complement thereof, wherein the desired DNA sequence and the complement thereof form a duplex comprising an edited portion which integrates into the target site to be edited. In some aspects, the systems comprise a first, second, third, and fourth prime editor complex, each comprising a prime editor and a PEgRNA. Also provided herein are methods for simultaneously editing both strands of a double-stranded DNA sequence at a target site to be edited. Further provided herein are pharmaceutical compositions, polynucleotides, vectors, cells, and kits. |
| FILED | Friday, December 08, 2023 |
| APPL NO | 18/534489 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/1276 (20130101) C12N 15/102 (20130101) Original (OR) Class C12N 15/111 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031127 | Zador et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
| ASSIGNEE(S) | COLD SPRING HARBOR LABORATORY (Cold Spring Harbor, New York) |
| INVENTOR(S) | Anthony Zador (Cold Spring Harbor, New York); Justus Kebschull (Cold Spring Harbor, New York) |
| ABSTRACT | The present invention provides a composition comprising a plurality of labeled neurons, each of which is labeled by an expression construct that encodes a unique barcoded nucleic acid. |
| FILED | Wednesday, April 05, 2017 |
| APPL NO | 16/091913 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/1808 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 15/09 (20130101) C12N 15/10 (20130101) C12N 15/102 (20130101) C12N 15/102 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 2770/36143 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 2522/101 (20130101) C12Q 2525/161 (20130101) C12Q 2535/122 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 70/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031135 | Patel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Vivekkumar B. Patel (Houston, Texas); Hongran Wang (Houston, Texas); Vivek P. Singh (Houston, Texas); Erin Lynn Reineke (Houston, Texas); Megumi Mathison (Houston, Texas); Austin J. Cooney (Houston, Texas); Todd Rosengart (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure include methods and compositions for in situ cardiac cell regeneration, including transdifferentiation of cardiac cells to cardiomyocytes. In particular embodiments, in situ cardiac cell regeneration encompasses delivery of p63 shRNA and one or both of Hand2 and myocardin, and in specific embodiments further includes one or more of Gata4, Mef2c, and Tbx5. In specific aspects of the disclosure, adult cardiac fibroblasts are reprogrammed into cardiomyocytes using viral vectors that harbor p63 shRNA and one or both of the transcription factors Hand2 and myocardin. |
| FILED | Tuesday, July 19, 2022 |
| APPL NO | 17/813493 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/47 (20130101) A61K 31/713 (20130101) A61K 38/1709 (20130101) A61K 48/0058 (20130101) Peptides C07K 14/82 (20130101) C07K 14/4702 (20130101) C07K 14/4746 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/1135 (20130101) C12N 2310/14 (20130101) C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2310/531 (20130101) C12N 2320/31 (20130101) C12N 2501/60 (20130101) C12N 2710/10043 (20130101) C12N 2740/15043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031136 | Kondo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma); The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma); The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Yuji Kondo (Oklahoma City, Oklahoma); Jianxin Fu (Oklahoma City, Oklahoma); Hua Wang (Oklahoma City, Oklahoma); Klaas Wierenga (Oklahoma City, Oklahoma); Patrick M. Gaffney (Oklahoma City, Oklahoma); Lijun Xia (Oklahoma City, Oklahoma) |
| ABSTRACT | The present invention includes a method of treating a bone disease caused by a intracellular protein trafficking defect comprising: identifying a subject having the bone disease caused by the intracellular protein trafficking defect in a membrane bound transcription factor peptidase, site 1 (MBTPS1) gene; and providing the subject with an effective amount of a composition that bypasses or corrects a defect in MBTPS1 gene expression, gene splicing, or corrects protein trafficking defects in the endoplasmic reticulum and to the lysosome. |
| FILED | Tuesday, October 23, 2018 |
| APPL NO | 16/758339 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/26 (20130101) A61K 31/155 (20130101) A61K 31/192 (20130101) A61K 31/436 (20130101) A61K 31/575 (20130101) A61K 31/4045 (20130101) A61K 38/05 (20130101) A61K 38/07 (20130101) A61K 38/08 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/08 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/64 (20130101) C12N 15/1137 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031146 | Barzel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Adi Barzel (Palo Alto, California); Mark A. Kay (Los Altos, California) |
| ABSTRACT | Methods and compositions are provided for editing the genome of a cell without the use of an exogenously supplied nuclease. Aspects of the methods include contacting a cell with a targeting vector comprising nucleic acid sequence to be integrated into the target locus, where the cell is not also contacted with a nuclease. In addition, reagents, devices and kits thereof that find use in practicing the subject methods are provided. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/322561 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1866 (20130101) A61K 48/005 (20130101) A61K 48/0008 (20130101) Peptides C07K 16/1045 (20130101) C07K 2317/76 (20130101) C07K 2319/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/644 (20130101) C12N 15/52 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 2750/14143 (20130101) C12N 2799/025 (20130101) C12N 2800/24 (20130101) C12N 2840/20 (20130101) Enzymes C12Y 304/21022 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031147 | Flannery et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Novartis AG (Basel, Switzerland) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Novartis AG (Basel, Switzerland) |
| INVENTOR(S) | John G. Flannery (Berkeley, California); Scott F. Geller (El Cerrito, California); Karen I. Guerin (Braintree, Massachusetts) |
| ABSTRACT | The present disclosure provides recombinant adeno-associated virus (AAV) virions comprising: a) a variant capsid protein; and b) a heterologous nucleic acid comprising one or more nucleotide sequences encoding one or more heterologous gene products. The rAAV virions are useful for delivery of gene products to a retinal cell. The present disclosure provides methods of delivering a gene product to a retinal cell in an individual. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/332855 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031153 | Khoshakhlagh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Parastoo Khoshakhlagh (Cambridge, Massachusetts); Hon Man Alex Ng (Cambridge, Massachusetts); George M. Church (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are pluripotent stem cells comprising particular combinations of transcription factor for the production of oligodendrocyte progenitor cells (OPCs). Also provided herein are methods of producing the pluripotent stem cells and methods of using the pluripotent stem cells to produce (OPCs) and oligodendrocytes. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/768348 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/90 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2506/45 (20130101) C12N 2800/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031156 | Sentman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Charles L. Sentman (Grantham, New Hampshire) |
| ABSTRACT | The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same. |
| FILED | Tuesday, May 12, 2020 |
| APPL NO | 16/872419 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 2035/124 (20130101) A61K 2039/585 (20130101) A61K 2039/5156 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2501/515 (20130101) C12N 2510/02 (20130101) C12N 2511/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031161 | Czech et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Michael P. Czech (Westborough, Massachusetts); Emmanouela Tsagkaraki (Worcester, Massachusetts); Sarah M. Nicoloro (Holden, Massachusetts); Silvia Corvera (Westborough, Massachusetts) |
| ABSTRACT | Provided herein are methods and compositions for disrupting expression of nuclear receptor interacting protein 1 (Nrip1) in adipose cells, and methods of use of such adipose cells for treating, or reducing risk of, a condition associated with an elevated body mass index (BMI). |
| FILED | Friday, October 08, 2021 |
| APPL NO | 17/497367 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/35 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0653 (20130101) C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2506/13 (20130101) C12N 2510/00 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031183 | Newman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Aaron M. Newman (San Mateo, California); Arash Ash Alizadeh (San Mateo, California) |
| ABSTRACT | Methods of deconvolving a feature profile of a physical system are provided herein. The present method may include: optimizing a regression between a) a feature profile of a first plurality of distinct components and b) a reference matrix of feature signatures for a second plurality of distinct components, wherein the feature profile is modeled as a linear combination of the reference matrix, and wherein the optimizing includes solving a set of regression coefficients of the regression, wherein the solution minimizes 1) a linear loss function and 2) an L2-norm penalty function; and estimating the fractional representation of one or more distinct components among the second plurality of distinct components present in the sample based on the set of regression coefficients. Systems and computer readable media for performing the subject methods are also provided. |
| FILED | Wednesday, December 19, 2018 |
| APPL NO | 16/226270 |
| ART UNIT | 1672 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6881 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2537/165 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 25/10 (20190201) G16B 40/10 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031896 | Swami et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | Nathan Swami (Charlottesville, Virginia); Walter Varhue (Charlottesville, Virginia); Vahid Farmehini (Charlottesville, Virginia) |
| ABSTRACT | Disclosed herein are methods and systems that facilitate the integration of on-chip impedance sensors and measurement circuitries for quantifying the impedance/frequency response of microfluidic device under the same, or similar, conditions used for particle manipulation. The methods and systems can use a microfluidic chip comprising a microfluidic channel with one or more electric-field-generating structures located therein, including a first electric-field-generating structure, wherein the one or more electric-field-generating structures is configured to selectively polarize or manipulate biologic or particle components flowing within the microfluidic channel. The method and system can also employ a circuit configured for automated determination and quantification of parasitic voltage drops during AC electrokinetic particle manipulation, without the need to use valuable biological samples or model particles. The determined impedance response can be used to assess efficacy of the microfluidic device geometry as well as to provide control signals to inform downstream cell separation decisions. |
| FILED | Friday, January 24, 2020 |
| APPL NO | 17/425414 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 2200/0647 (20130101) B01L 2300/0627 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/01 (20240101) G01N 15/1031 (20130101) Original (OR) Class G01N 33/4833 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 27/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031897 | Pertsinidis |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Alexandros Pertsinidis (New York, New York) |
| ABSTRACT | A target may be tagged, and its position tracked to maintain the position of the target at the center (e.g., zero region) of a suppression beam, where suppression is minimal, so the signal from the target is not suppressed relative to signal from background molecules. Point scanning is not needed, as a pixelated detector of a camera can be used to acquire the position of the target in one shot. Images of the object from the pixelated detector can be analyzed to acquire the position of the target. To maintain the target in the zero, the beams may be steered onto the target. Alternatively or additionally, the sample may be moved to place the sample in the center. A correction signal may be sent to cause the sample and/or beams to be moved to maintain the target in position. |
| FILED | Monday, March 30, 2020 |
| APPL NO | 17/598648 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1433 (20240101) Original (OR) Class G01N 21/64 (20130101) G01N 21/6458 (20130101) G01N 2015/0038 (20130101) G01N 2021/6478 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031912 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Jason Liu (Durham, North Carolina); Ashutosh Chilkoti (Durham, North Carolina) |
| ABSTRACT | A microarray chip imaging detector comprises a housing configured to receive a microarray chip. The detector includes a laser assembly supported by the housing and oriented at an angle relative to the microarray chip, the laser assembly configured to transmit an excitation beam along a first axis to samples on the microarray chip. The detector also includes a camera supported by the housing and positioned along a second axis, the camera configured to receive fluorescent light emitted from fluorophores in the samples on the microarray chip, the second axis oriented at an angle less than 30 degrees relative to the first axis. The housing includes a plurality of baffles positioned between the microarray chip and the camera, and a plurality of laser beamstops to receive the excitation beam reflected off the microarray chip. |
| FILED | Saturday, May 02, 2020 |
| APPL NO | 17/607761 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6402 (20130101) G01N 21/6428 (20130101) G01N 21/6452 (20130101) Original (OR) Class G01N 21/6456 (20130101) G01N 2021/6439 (20130101) G01N 2201/022 (20130101) G01N 2201/0642 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031977 | Langer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Robert S. Langer (Newton, Massachusetts); Carlo Giovanni Traverso (Newton, Massachusetts); Yunhua Shi (Belmont, Massachusetts); Vance Soares (Boston, Massachusetts); Daniel Reker (Durham, North Carolina) |
| ABSTRACT | Methods and compositions for determining multiplex interactions between drugs and drug transporters using an intestinal tissue explant are provided. |
| FILED | Thursday, December 10, 2020 |
| APPL NO | 17/118267 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) G01N 33/5088 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031981 | Lindsay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Stuart Lindsay (Scottsdale, Arizona); Bintian Zhang (Scottsdale, Arizona) |
| ABSTRACT | The present disclosure relates to a sensing device and methods for detecting, and quantifying the amount of, a target protein in a sample. |
| FILED | Wednesday, May 08, 2019 |
| APPL NO | 17/053522 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5438 (20130101) Original (OR) Class G01N 33/6854 (20130101) G01N 33/48721 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031985 | Bowers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | First Light Biosciences, Inc. (Chelmsford, Massachusetts) |
| ASSIGNEE(S) | FIRST LIGHT DIAGNOSTICS, INC. (Chelmsford, Massachusetts) |
| INVENTOR(S) | Jayson L. Bowers (Cambridge, Massachusetts); Michael Cappillino (Haverhill, Massachusetts); Sadanand Gite (Arlington, Massachusetts); Don Straus (Charlestown, Massachusetts) |
| ABSTRACT | Methods and cartridges for detecting targets are provided. A biological sample is introduced to a cartridge. Targets in the sample are photonically labeled with fluorescent particles in a first liquid layer in the cassette. Photonically-labeled targets are separated out of the sample into a second liquid layer within the cassette, detected, and counted to show presence of the targets in the subject. Cartridges include a receiving reservoir, a mixing well for introducing the sample to photonic labels and magnetic particles, and an imaging well for detecting and counting targets from the sample. The sample may be a human stool sample. A filter may be used to filter particulates out of the sample. |
| FILED | Friday, April 19, 2019 |
| APPL NO | 16/389852 |
| ART UNIT | 1677 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5025 (20130101) B01L 2300/0681 (20130101) B01L 2400/043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 33/582 (20130101) G01N 33/5302 (20130101) G01N 33/54326 (20130101) G01N 33/56911 (20130101) Original (OR) Class G01N 2021/6439 (20130101) G01N 2469/10 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12032107 | Olcott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RefleXion Medical, Inc. (Hayward, California) |
| ASSIGNEE(S) | RefleXion Medical, Inc. (Hayward, California) |
| INVENTOR(S) | Peter Demetri Olcott (Los Gatos, California); Matthew Francis Bieniosek (Danville, California); Brent Harper (New Glarus, Wisconsin) |
| ABSTRACT | Disclosed herein are methods and devices for the acquisition of positron emission (or PET) data in the presence of ionizing radiation that causes afterglow of PET detectors. In one variation, the method comprises adjusting a coincidence trigger threshold of the PET detectors during a therapy session. In one variation, the method comprises adjusting a gain factor used in positron emission data acquisition (e.g., a gain factor used to multiply and/or shift the output(s) of a PET detector(s)) during a therapy session. In some variations, a method for acquiring positron emission data during a radiation therapy session comprises suspending communication between the PET detectors and a signal processor of a controller for a predetermined period of time after a radiation pulse has been emitted by the linac. |
| FILED | Tuesday, May 02, 2023 |
| APPL NO | 18/311134 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/172 (20130101) G01T 1/208 (20130101) G01T 1/2023 (20130101) G01T 1/2985 (20130101) Original (OR) Class G01T 7/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12032108 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Xin Li (Tucson, Arizona); Lars Furenlid (Tucson, Arizona) |
| ABSTRACT | The present invention provides a method of calibrating gamma-ray and photon counting detectors, including, but not limited to, monolithic crystal detectors. The method of the present invention is based on the observation that measurement of fan beam datasets allows the synthesis of collimated beam data to derive MDRFs by use of an algorithm that finds the common or intersecting data subsets of two or more orthogonal calibration datasets. This makes the calibration process very efficient while still allowing the full benefits of maximum-likelihood event-parameter estimation that incorporates the statistical nature of the light sensor measurements. |
| FILED | Tuesday, December 20, 2022 |
| APPL NO | 18/068882 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/202 (20130101) G01T 1/2018 (20130101) G01T 1/2964 (20130101) G01T 7/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12033726 | Chennubhotla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh-Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Srinivas C. Chennubhotla (Pittsburgh, Pennsylvania); Albert H. Gough (Glenshaw, Pennsylvania); Andrew M. Stern (Pittsburgh, Pennsylvania); Michael J. Becich (Wexford, Pennsylvania); Douglass L Taylor (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method of generating a plurality of spatially co-registered data elements, each spatially co-registered data element being associated with and generated from a pair of co-registered tissue sections obtained from adjacent positions of a core taken from a tissue sample and including an image data section and a genomic data section. The method includes, for each pair of co-registered tissue sections: (i) obtaining and storing as part of a data element a plurality of multi to hyperplexed images from the imaging data section of the co-registered tissue section, (ii) generating and storing as part of the data element image data from the plurality of multi to hyperplexed images, and (iii) generating and storing as part of the data element genomic data from the genomic data section of the associated co-registered tissue section. |
| FILED | Wednesday, August 21, 2019 |
| APPL NO | 17/265954 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 1/2806 (20130101) Electric Digital Data Processing G06F 3/0482 (20130101) G06F 3/04817 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2200/24 (20130101) G06T 2207/30024 (20130101) G06T 2207/30072 (20130101) G06T 2207/30096 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/10 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12033740 | Papaioannou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vasileios K. Papaioannou (Baltimore, Maryland); Quan Chen (Lexington, Kentucky); Xue Feng (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vasileios K. Papaioannou (Baltimore, Maryland); Quan Chen (Lexington, Kentucky); Xue Feng (Lexington, Kentucky) |
| ABSTRACT | The present disclosure relates to a method and apparatus for robust and automatic face de-identification from CT and MRI. The method includes: receiving DICOM files of patient bodies obtained by a CT or MRI system; normalizing the images; extracting the heads from bodies; creating face masks; and writing DICOM files back with de-identified faces. |
| FILED | Saturday, December 04, 2021 |
| APPL NO | 17/542409 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) Original (OR) Class G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12029577 | Cotero et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GE Precision Healthcare LLC (Wauwatosa, Wisconsin) |
| INVENTOR(S) | Victoria Eugenia Cotero (Troy, New York); Christopher Michael Puleo (Niskayuna, New York); John Frederick Graf (Ballston Lake, New York) |
| ABSTRACT | The subject matter of the present disclosure generally relates to techniques for neuromodulation that include applying energy (e.g., ultrasound energy) into the tissue to cause a change in a glucose transporter pathway molecule and/or an incretin pathway molecule. In one embodiment, the neuromodulation is performed as a treatment of a metabolic disorder. |
| FILED | Thursday, March 12, 2020 |
| APPL NO | 17/437731 |
| ART UNIT | 3797 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4244 (20130101) Original (OR) Class A61B 5/4848 (20130101) A61B 5/14532 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) A61N 2007/0026 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/66 (20130101) G01N 33/6872 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029699 | Van Engelhoven et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | suitX, Inc. (Emeryville, California) |
| ASSIGNEE(S) | suitX, Inc. (Emeryville, California) |
| INVENTOR(S) | Logan Van Engelhoven (Emeryville, California); James Hatch (Emeryville, California) |
| ABSTRACT | A remote center joint 1 is configured to rotate segment 7 relative to segment 2 along axis 15. Remote center joint 1 comprises a segment 3 coupled to base segment 2 along axis 16. Segment 4 is coupled to segment 3 about axis 17 intersecting axis 16 at first point 22. Segment 4 is coupled to segment 7 about axis 18 intersecting first point 22. Segment 5 is coupled to segment 2 about axis 19 parallel to axis 16. Segment 5 is geared to segment 3. Segment 6 is coupled to segment 5 about axis 20 intersecting axis 19 at second point 23. Segment 6 is coupled to segment 7 along axis 21 intersecting second point 23. Segment 6 is geared to segment 4. Axis 15 of rotation of terminal segment 7 relative to segment 2 connects first point 22 and second point 23. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/206814 |
| ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0281 (20130101) Original (OR) Class A61H 2201/165 (20130101) A61H 2201/1671 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029717 | Massague et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Joan Massague (New York, New York); Adrienne Boire (New York, New York); Qing Chen (Palisades Park, New Jersey) |
| ABSTRACT | The present invention relates to methods for treating brain metastasis by inhibiting gap junction functionality. It is based, at least in part, on the discovery that cancer cells expressing Protocadherin 7 and Connexin 43 form gap junctions with astrocytes that promote the growth of brain metastases, and that inhibition of Protocadherin 7 and/or Connexin 43 expression in cancer cells reduce progression of brain metastases. It is further based on the discovery that treatment with gap junction inhibitors tonabersat and meclofenamate inhibited progression of brain metastatic lesions and enhanced the anti-cancer activity of the conventional chemotherapeutic agent, carboplatin. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 17/345572 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/196 (20130101) A61K 31/196 (20130101) A61K 31/282 (20130101) A61K 31/352 (20130101) Original (OR) Class A61K 31/352 (20130101) A61K 31/555 (20130101) A61K 31/555 (20130101) A61K 31/7105 (20130101) A61K 31/7105 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/04 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 2333/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029907 | Kahana et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Michael Kahana (Merion Station, Pennsylvania); Daniel Sutton Rizzuto (Philadelphia, Pennsylvania) |
| ABSTRACT | Methods and apparatus for improving cognitive function within a human. The invention utilizes a neurostimulation device, such as a signal generator, to affect tissue elements at a lateral temporal lobe of the human brain. The implanted device delivers treatment therapy to thereby improve cognitive function by the human. A sensor may be used to detect various characteristics of cognition. A microprocessor algorithm may then analyze the output from the sensor to regulate delivery of the stimulation therapy. |
| FILED | Wednesday, July 19, 2017 |
| APPL NO | 16/318738 |
| ART UNIT | 3796 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 5/291 (20210101) A61B 5/369 (20210101) A61B 5/686 (20130101) A61B 5/4064 (20130101) A61B 5/4088 (20130101) A61B 5/4836 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0531 (20130101) A61N 1/36082 (20130101) A61N 1/36092 (20130101) Original (OR) Class A61N 1/36139 (20130101) A61N 1/36157 (20130101) A61N 1/36171 (20130101) A61N 1/36175 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030081 | Park et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Jiwoong Park (Chicago, Illinois); Yu Zhong (Chicago, Illinois); Baorui Cheng (Chicago, Illinois) |
| ABSTRACT | Disclosed herein are inventive methods of making thin films, inventive thin films, and inventive articles and systems comprising thin films. Certain embodiments are related to methods of making thin films in which reagents are arranged within a first phase and a second phase such that at least one reagent reacts to form a thin film proximate to the interface between the first phase and the second phase. Thin films (including two-dimensional materials) disclosed herein can have one or more of a variety of beneficial properties including large lateral dimension(s), lateral continuity, high mechanical strength, consistent spatial composition, and/or consistent thickness. In accordance with certain embodiments, thin films disclosed herein can be combined to form a variety of inventive multi-layer articles, including multi-layer articles comprising a combination of thin films having different compositions that interact with each other via van der Waals forces. |
| FILED | Tuesday, October 06, 2020 |
| APPL NO | 17/767125 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/20 (20130101) B05D 1/185 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030864 | Law et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Brian Keith Law (Gainesville, Florida); Ronald K. Castellano (Gainesville, Florida) |
| ABSTRACT | The invention relates to methods of treating cell proliferative disorders. The invention further relates to pharmaceutical compositions for treating cell proliferative disorders, especially cancer. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 17/251289 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/33 (20130101) A61K 31/385 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 339/00 (20130101) C07D 339/04 (20130101) C07D 339/08 (20130101) Original (OR) Class C07D 345/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030930 | Mauzy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Camilla A Mauzy (Enon, Ohio); Serge Victor Marie Muyldermans (Brussels, Belgium) |
| ABSTRACT | Single-domain antibodies (SAbs) against three Yersinia pestis surface proteins (LcrV, YscF, and F1), nucleic acid sequences encoding the SAbs, and polypeptides comprising two or more SAbs capable of recognizing two or more epitopes and/or antigens. The present invention further includes methods for preventing or treating Y. pestis infections in a patient; methods for detecting and/or diagnosing Y. pestis infections; and devices and methods for identifying and/or detecting Y. pestis on a surface and/or in an environment. |
| FILED | Tuesday, January 05, 2021 |
| APPL NO | 17/141515 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1228 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030931 | Mauzy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Camilla A Mauzy (Enon, Ohio); Serge Victor Marie Muyldermans (Brussels, Belgium) |
| ABSTRACT | Single-domain antibodies (SAbs) against three Yersinia pestis surface proteins (LcrV, YscF, and F1), nucleic acid sequences encoding the SAbs, and polypeptides comprising two or more SAbs capable of recognizing two or more epitopes and/or antigens. The present invention further includes methods for preventing or treating Y. pestis infections in a patient; methods for detecting and/or diagnosing Y. pestis infections; and devices and methods for identifying and/or detecting Y. pestis on a surface and/or in an environment. |
| FILED | Tuesday, January 05, 2021 |
| APPL NO | 17/141533 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1228 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030932 | Mauzy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Camilla A Mauzy (Enon, Ohio); Serge Victor Marie Muyldermans (Brussels, Belgium) |
| ABSTRACT | Single-domain antibodies (SAbs) against three Yersinia pestis surface proteins (LcrV, YscF, and F1), nucleic acid sequences encoding the SAbs, and polypeptides comprising two or more SAbs capable of recognizing two or more epitopes and/or antigens. The present invention further includes methods for preventing or treating Y. pestis infections in a patient; methods for detecting and/or diagnosing Y. pestis infections; and devices and methods for identifying and/or detecting Y. pestis on a surface and/or in an environment. |
| FILED | Tuesday, January 05, 2021 |
| APPL NO | 17/141554 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1228 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031026 | Kengla |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WAKE FOREST UNIVERSITY HEALTH SCIENCES (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| INVENTOR(S) | Carlos Kengla (Winston-Salem, North Carolina) |
| ABSTRACT | Provided herein are improved compositions and methods of making and using the same, the composition comprising a polymer and a ceramic present at a ratio of from 3:1 to 1:3 of polymer:ceramic by weight, wherein the composition comprises or is a composite of the polymer and the ceramic having improved printability and/or having an improved elastic modulus and/or improved stress at failure (e.g., as compared to a blend of the polymer and the ceramic). Improved medical implants incorporating the same are also provided. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/263222 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/46 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 27/3847 (20130101) A61L 2430/02 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 64/205 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2067/04 (20130101) B29K 2509/02 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/32 (20130101) C08K 3/32 (20130101) C08K 2003/325 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) Original (OR) Class C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031074 | Sherburne |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Michael D. Sherburne (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to devices for measuring property changes via in-situ micro-viscometry and methods of using same. The aforementioned device is inexpensive and can be used to quickly and accurately measure numerous physical and chemical property changes, including but not limited to the rate of chemical cure, change in tack, and rate of mass loss, for example, rate of moisture, solvent and/or plasticizer change. |
| FILED | Tuesday, August 25, 2020 |
| APPL NO | 17/001719 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/067 (20130101) B05D 7/546 (20130101) B05D 2350/60 (20130101) B05D 2504/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/22 (20130101) C09D 163/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/883 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031084 | Luhrs |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Claudia Catalina Luhrs (Pacific Grove, California) |
| ABSTRACT | The invention relates to a polymeric composite. The polymeric composite includes a polymeric matrix that further includes a thermoset polymer and a phase change material that has been mixed with the polymeric matrix using a thickening agent. In some cases, the polymeric composite is at least 10% by weight of the phase change material. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/937495 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/04 (20130101) C08K 3/38 (20130101) C08K 5/01 (20130101) C08K 13/02 (20130101) Compositions of Macromolecular Compounds C08L 61/00 (20130101) C08L 61/28 (20130101) C08L 79/08 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/02 (20130101) C09K 5/06 (20130101) C09K 5/063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031161 | Czech et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Michael P. Czech (Westborough, Massachusetts); Emmanouela Tsagkaraki (Worcester, Massachusetts); Sarah M. Nicoloro (Holden, Massachusetts); Silvia Corvera (Westborough, Massachusetts) |
| ABSTRACT | Provided herein are methods and compositions for disrupting expression of nuclear receptor interacting protein 1 (Nrip1) in adipose cells, and methods of use of such adipose cells for treating, or reducing risk of, a condition associated with an elevated body mass index (BMI). |
| FILED | Friday, October 08, 2021 |
| APPL NO | 17/497367 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/35 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0653 (20130101) C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2506/13 (20130101) C12N 2510/00 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031183 | Newman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Aaron M. Newman (San Mateo, California); Arash Ash Alizadeh (San Mateo, California) |
| ABSTRACT | Methods of deconvolving a feature profile of a physical system are provided herein. The present method may include: optimizing a regression between a) a feature profile of a first plurality of distinct components and b) a reference matrix of feature signatures for a second plurality of distinct components, wherein the feature profile is modeled as a linear combination of the reference matrix, and wherein the optimizing includes solving a set of regression coefficients of the regression, wherein the solution minimizes 1) a linear loss function and 2) an L2-norm penalty function; and estimating the fractional representation of one or more distinct components among the second plurality of distinct components present in the sample based on the set of regression coefficients. Systems and computer readable media for performing the subject methods are also provided. |
| FILED | Wednesday, December 19, 2018 |
| APPL NO | 16/226270 |
| ART UNIT | 1672 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6881 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2537/165 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 25/10 (20190201) G16B 40/10 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031236 | Skinner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jack L. Skinner (Butte, Montana); Emily A. Kooistra-Manning (Butte, Montana); Jessica M. Andriolo (Butte, Montana); Lane G. Huston (Butte, Montana) |
| ASSIGNEE(S) | Montana Technological University (Butte, Montana) |
| INVENTOR(S) | Jack L. Skinner (Butte, Montana); Emily A. Kooistra-Manning (Butte, Montana); Jessica M. Andriolo (Butte, Montana); Lane G. Huston (Butte, Montana) |
| ABSTRACT | Electrospinning (ES) produces fibers with small cross-sections and high surface area, making them ideal for a multitude of applications. Structures produced using ES methods exhibit a high surface-to-volume ratio, tunable porosity, and controllable composition. ES involves the delivery of a liquid or solid polymer to a spinneret, whereby, an initiated electric field pulls the polymer into micro to nano-scale fibers. Due to the multitude of applications for which polymer fibers can be used, it is desirable to provide an efficient and portable ES device that allows on-demand deposition of polymer materials. The invention that is subject of this patent application is a portable ES device that allows ideal deposition on a substrate regardless of whether that substrate is attached to high voltage or grounded, and regardless of whether or not there is a charged or grounded substrate behind the desired deposition surface. |
| FILED | Saturday, May 30, 2020 |
| APPL NO | 17/614540 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/003 (20130101) D01D 5/0023 (20130101) D01D 5/0084 (20130101) Original (OR) Class Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/08 (20130101) D01F 1/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031786 | Drew et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Knight's Armament, LLC (Titusville, Florida) |
| ASSIGNEE(S) | Knight's Armament, LLC (Titusville, Florida) |
| INVENTOR(S) | Joshua R. Drew (Orlando, Florida); C. Reed Knight, Jr. (Titusville, Florida); Charles Christopher Hoffman (Satellite Beach, Florida); Murphy S. Walden (Orlando, Florida) |
| ABSTRACT | A suppressor for reducing muzzle flash during firing of a firearm. The suppressor includes an auto purge channel configured to direct gas to a distal end of the suppressor adjacent an exit point of a projectile. In one example, the auto purge channel enables gas to saturate an area of the suppressor in front of the projectile. For example, the auto purge channel directs gas to the distal end of the suppressor at a speed that is greater than a speed of the projectile. In another embodiment, the projectile travels through combustion gasses transferred by the auto purge channel to reduce muzzle flash. In yet another example, the auto purge channel runs parallel to a central bore of the suppressor. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/936938 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/30 (20130101) Original (OR) Class F41A 21/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031798 | Dwyer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AimLock Inc. (Littleton, Colorado) |
| ASSIGNEE(S) | AIMLOCK INC. (Littleton, Colorado) |
| INVENTOR(S) | Benjamin Dwyer (Littleton, Colorado); Bryan Sterling Bockmon (Littleton, Colorado); Raymond Keeney (Littleton, Colorado); Jason R. Gallia (Littleton, Colorado); Shane Korthuis (Littleton, Colorado); Dusty Terry (Littleton, Colorado); Marc Hanchak (Littleton, Colorado) |
| ABSTRACT | A weapon mount for controlling targeting of a weapon includes a base, an arm that extends from the base, and an attachment component that is rotatably coupled with the arm. The base is attachable to a platform and is rotatable to control a yaw of the weapon relative to the platform. The attachment component is configured to couple with the weapon and is rotatable to control a pitch of the weapon relative to the platform. The arm is positioned relative to the base so that a recoil vector of the weapon is within 0.5 inches radially of an axis of rotation of the base. |
| FILED | Friday, March 11, 2022 |
| APPL NO | 17/693091 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 23/06 (20130101) F41A 23/52 (20130101) Weapon Sights; Aiming F41G 3/165 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031803 | Mathis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southwest Research Institute (San Antonio, Texas) |
| ASSIGNEE(S) | Southwest Research Institute (San Antonio, Texas) |
| INVENTOR(S) | James T Mathis (Fair Oaks Ranch, Texas); Matthew V. Grimm (San Antonio, Texas); Nicholas J. Mueschke (San Antonio, Texas); Edward V. O'Hare (San Antonio, Texas) |
| ABSTRACT | An arena test system for characterizing fragments from a warhead. An entry panel and an exit panel are arranged in a wedge configuration with a wedge-shaped air space between them. Fragments are imaged as they pass through this wedge. A soft catch box is located behind the exit panel such that fragments that pass through the exit panel enter the soft catch box and are decelerated within the soft catch box. |
| FILED | Sunday, January 23, 2022 |
| APPL NO | 17/581951 |
| ART UNIT | 2672 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/20 (20130101) F42B 35/00 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/207 (20170101) G06T 2207/10016 (20130101) G06T 2207/30241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031814 | Mohan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California) |
| ASSIGNEE(S) | Xerox Corporation (Norwalk, Connecticut) |
| INVENTOR(S) | Shiwali Mohan (Palo Alto, California); Matthew Klenk (San Francisco, California); Matthew Shreve (Campbell, California); Aaron Ang (Mountain View, California); John Turner Maxwell, III (Santa Clara, California); Kent Evans (Cupertino, California) |
| ABSTRACT | A method is provided. The method includes obtaining sensor data indicative of a set of objects detected within an environment. The method also includes generating a state graph based on the sensor data. The state graph includes a set of object nodes and a set of property nodes. The method further includes obtaining user input data generated based on a natural language input. The method further includes updating the state graph based on the user input data to generate an enhanced state graph. The enhanced state graph includes additional nodes generated based on the user input data. The method further includes generating a set of instructions for a set of mechanical systems based on the enhanced state graph. The method further includes operating the set of mechanical systems to achieve a set of objectives based on the set of instructions. |
| FILED | Wednesday, November 03, 2021 |
| APPL NO | 17/518429 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/163 (20130101) B25J 9/1664 (20130101) B25J 13/003 (20130101) B25J 13/089 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/003 (20130101) Original (OR) Class G01B 7/023 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) Electric Digital Data Processing G06F 18/21375 (20230101) G06F 40/10 (20200101) G06F 40/40 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031912 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Jason Liu (Durham, North Carolina); Ashutosh Chilkoti (Durham, North Carolina) |
| ABSTRACT | A microarray chip imaging detector comprises a housing configured to receive a microarray chip. The detector includes a laser assembly supported by the housing and oriented at an angle relative to the microarray chip, the laser assembly configured to transmit an excitation beam along a first axis to samples on the microarray chip. The detector also includes a camera supported by the housing and positioned along a second axis, the camera configured to receive fluorescent light emitted from fluorophores in the samples on the microarray chip, the second axis oriented at an angle less than 30 degrees relative to the first axis. The housing includes a plurality of baffles positioned between the microarray chip and the camera, and a plurality of laser beamstops to receive the excitation beam reflected off the microarray chip. |
| FILED | Saturday, May 02, 2020 |
| APPL NO | 17/607761 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6402 (20130101) G01N 21/6428 (20130101) G01N 21/6452 (20130101) Original (OR) Class G01N 21/6456 (20130101) G01N 2021/6439 (20130101) G01N 2201/022 (20130101) G01N 2201/0642 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031919 | Jiang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Peng Jiang (Gainesville, Florida); Zhuxiao Gu (Gainesville, Florida); Sin-Yen Leo (Gainesville, Florida) |
| ABSTRACT | Described are chromogenic sensors, methods of use, and kits including sensors. The sensors can have a polymer structure with a waveform cross-section in a programmed state. Upon exposure to a first liquid, the polymer structure in the programmed state changes to polymer structure in an activated state. Methods for measuring the presence of a liquid using the sensor are described, as are kits including the sensors. |
| FILED | Thursday, September 01, 2022 |
| APPL NO | 17/901286 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031954 | Rudolf |
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| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Christopher Rudolf (Washington, District of Columbia) |
| ABSTRACT | A method of measuring millisecond-scale blast and impact characterization in soft materials includes embedding one or more sensors in soft material, wherein the one or more sensors have mechanical properties approximately matching the soft material; applying a constant current to the one or more sensors; subjecting the soft material to a shock or impact event; measuring a response as a change in voltage; and converting the measured voltage to strain or pressure. |
| FILED | Wednesday, February 24, 2021 |
| APPL NO | 17/184030 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/30 (20130101) Original (OR) Class G01N 3/066 (20130101) G01N 2203/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12032010 | Caliga |
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| FUNDED BY |
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| APPLICANT(S) | ColdQuanta, Inc. (Boulder, Colorado) |
| ASSIGNEE(S) | ColdQuanta, Inc. (Boulder, Colorado) |
| INVENTOR(S) | Seth Charles Caliga (Lafayette, Colorado) |
| ABSTRACT | An electrometer is disclosed. The electrometer includes a housing, a vapor cell, a micro-optical system, an electric field generator, and a control electronic subsystem. The vapor cell has a top and a bottom and includes a vapor of quantum particles. The micro-optical system is configured to route laser fields through the vapor cell in a direction transverse to the top and the bottom. The electric field generator is configured to provide an electric field in the vapor cell. The housing includes a surface adapted to mate to a portion of a fuselage surrounding a hole. |
| FILED | Thursday, May 25, 2023 |
| APPL NO | 18/202063 |
| ART UNIT | 2634 — Digital Communications |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/12 (20130101) Original (OR) Class G01R 29/0878 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12032044 | Braje et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Danielle A. Braje (Winchester, Massachusetts); Jennifer Schloss (Cambridge, Massachusetts); Linh M. Pham (Arlington, Massachusetts); John F. Barry (Arlington, Massachusetts); Erik R. Eisenach (Cambridge, Massachusetts); Michael F. O'Keeffe (Medford, Massachusetts); Jonah A. Majumder (Cambridge, Massachusetts); Jessica Kedziora (Shirley, Massachusetts); Peter Moulton (Concord, Massachusetts); Matthew Steinecker (Medford, Massachusetts) |
| ABSTRACT | We have developed a high-performance, low-volume, low-weight, and low-power sensor based on a self-sustaining oscillator. The techniques described here may be used for sensing various fields; we demonstrate magnetic sensing. The oscillator is based on a dielectric resonator that contains paramagnetic defects and is connected to a sustaining amplifier in a feedback loop. The resonance frequency of the dielectric resonator shifts in response to changes in the magnetic field, resulting in a shift in the frequency of the self-sustaining oscillator. The value of the magnetic field is thereby encoded in the shift or modulation output of the self-sustaining oscillator. The sensor as demonstrated uses no optics, no input microwaves, and, not including digitization electronics, consumes less than 300 mW of power and exhibits a sensitivity at or below tens of pT/√{square root over (Hz)}. In some implementations, the sensor is less than 1 mL in volume. |
| FILED | Monday, December 28, 2020 |
| APPL NO | 17/134589 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/24 (20130101) Original (OR) Class Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 1/18 (20130101) H01P 3/06 (20130101) H01P 5/18 (20130101) H01P 7/10 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/1864 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12032118 | Guo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Cheng Guo (Stanford, California); Meng Xiao (Wuhan, China PRC); Momchil Minkov (San Mateo, California); Yu Shi (Redmond, Washington); Shanhui Fan (Stanford, California) |
| ABSTRACT | An isotropic imaging filter is provided that includes a photonic crystal slab, where the photonic crystal slab includes a square lattice of air through holes, a dielectric constant, a thickness (d), a through hole radius (r), and a lattice constant (a), where the square lattice of air holes are separated according to a value of the lattice constant, where the thickness is configured according to d=M(a), where the through hole radii is configured according to r=N(a), where the thickness and the hole radii are configured to generate isotropic bands of guided resonances of an incident image. |
| FILED | Monday, February 22, 2021 |
| APPL NO | 17/181318 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 1/005 (20130101) Original (OR) Class G02B 5/20 (20130101) G02B 5/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12032373 | Eldred et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ross Anthony Eldred (Pacific Grove, California); Jonathan Lussier (Broomfield, Colorado) |
| ABSTRACT | The invention relates to an autonomous underwater vehicle (AUV). The AUV includes a frame and tunnel thrusters for propelling and orientating the AUV, where the tunnel thrusters have inlets and outlets, each of outlets being directed in a different orientation, and are mounted to the frame. The AUV further includes fasteners for connecting the frame to a hull, where the fasteners have an orientation that is substantially parallel to the tunnel thrusters. The hull has a substantially spherical shape and further includes (1) a bottom plate with inlet openings, (2) a top plate with outlet openings, where the top plate and the bottom plate are affixed to the fasteners and hold plate rings of the hull in place, and (3) each of the plate rings that further includes a corresponding retention ring and corresponding central plates. |
| FILED | Monday, September 21, 2020 |
| APPL NO | 17/027682 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 79/15 (20200101) B63B 79/40 (20200101) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/08 (20130101) B63G 2008/004 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/048 (20130101) G05D 1/0088 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12032501 | Landry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Blake J. Landry (Saint Martinville, Louisiana); Charles R. Key (Diamondhead, Mississippi); Edward F. Braithwaite, III (Covington, Louisiana) |
| ABSTRACT | A central payload manager device may include a network switch, a central payload manager processing device, a plurality of connecting interfaces, a plurality of sensor processing devices connected to corresponding ones of the connecting interfaces and to the network switch, a cell modem or radio link connected to one or more of the connecting interfaces and to the network switch, a data storage device connected to the processing device, wherein the data storage device is configured to receive and store information from the plurality of sensor processing devices and from the cell modem or radio link via the network switch and the central payload manager processing device; and an iridium modern connecting to the central payload manager processing device and to a corresponding one of the connecting interfaces, wherein the iridium modem is configured to receive and transmit the stored information from the data storage device to an iridium antenna. |
| FILED | Thursday, October 06, 2022 |
| APPL NO | 17/961530 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/38 (20130101) Electric Digital Data Processing G06F 13/20 (20130101) Original (OR) Class G06F 2213/40 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/40013 (20130101) H04L 2012/40273 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12033233 | Kishore et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Varsha Kishore (Ithaca, New York); Kilian Weinberger (Ithaca, New York); Xiangyu Chen (Ithaca, New York); Boyi Li (New York, New York); Yan Wang (Ithaca, New York); Ruihan Wu (Ithaca, New York) |
| ABSTRACT | A method performed by at least one processing device in an illustrative embodiment comprises applying a first image and a message to an encoder of a steganographic encoder-decoder neural network, generating in the encoder, based at least in part on the first image and the message, a perturbed image containing the message, decoding the perturbed image in a decoder of the steganographic encoder-decoder neural network, and providing information characterizing the decoded perturbed image to the encoder. The generating, decoding and providing are iteratively repeated, with different perturbations being determined in the encoder as a function of respective different instances of the provided information, until the decoded perturbed image meets one or more specified criteria relative to the message. The perturbed image corresponding to the decoded perturbed image that meets the one or more specified criteria relative to the message is output as a steganographic image containing the message. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 18/557361 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0442 (20230101) G06N 3/0455 (20230101) Image Data Processing or Generation, in General G06T 1/005 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 40/16 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034049 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Samsung Electronics Co., Ltd. (Suwon-si, South Korea); THE UNIVERSITY OF CHICAGO (Chicago, Illinois); Center for Technology Licensing at Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Samsung Electronics Co., Ltd. (Gyeonggi-do, South Korea); The University of Chicago (Chicago, Illinois); Center for Technology Licensing at Cornell University (Ithaca, New York) |
| INVENTOR(S) | Minhyun Lee (Suwon-si, South Korea); Jiwoong Park (Chicago, Illinois); Saien Xie (Ithaca, New York); Jinseong Heo (Seoul, South Korea); Hyeonjin Shin (Suwon-si, South Korea) |
| ABSTRACT | Provided are a superlattice structure including a two-dimensional material and a device including the superlattice structure. The superlattice structure may include at least two different two-dimensional (2D) materials bonded to each other in a lateral direction, and an interfacial region of the at least two 2D materials may be strained. The superlattice structure may have a bandgap adjusted by the interfacial region that is strained. The at least two 2D materials may include first and second 2D materials. The first 2D material may have a first bandgap in an intrinsic state thereof. The second 2D material may have a second bandgap in an intrinsic state thereof. An interfacial region of the first and second 2D materials and an adjacent region may have a third bandgap between the first bandgap and the second bandgap. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 18/052017 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/158 (20130101) Original (OR) Class H01L 29/1054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034180 | Kamavaram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oceanit Laboratories, Inc. (Honolulu, Hawaii) |
| ASSIGNEE(S) | Oceanit Laboratories, Inc. (Honolulu, Hawaii) |
| INVENTOR(S) | Venkat Kamavaram (Honolulu, Hawaii); Ganesh Kumar Arumugam (Honolulu, Hawaii); Sumil Singh Thapa (Honolulu, Hawaii) |
| ABSTRACT | The invention relates to nanostructured hybrid polymer composite membranes and methods for producing same. Specifically, the invention relates to nanofiber membranes produced through various methods, including electrospinning of at least one polymer into a non-woven nanofiber structure. The disclosed nanofiber membranes may also be compressed to further provide unique physical, chemical, and thermal properties that make such membranes suitable for a range of specific applications, including, but not limited to, use as nanostructured separators in lithium-ion batteries. |
| FILED | Wednesday, January 09, 2019 |
| APPL NO | 16/243877 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 50/42 (20210101) H01M 50/44 (20210101) Original (OR) Class H01M 50/403 (20210101) H01M 50/414 (20210101) H01M 50/423 (20210101) H01M 50/454 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034215 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Douglas Mark Wilson (King George, Virginia); Blake Charles Duff (Fredericksburg, Virginia); Jon Cameron Pouncey (Fredericksburg, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Douglas Mark Wilson (King George, Virginia); Blake Charles Duff (Fredericksburg, Virginia); Jon Cameron Pouncey (Fredericksburg, Virginia) |
| ABSTRACT | A slotted waveguide array (SWA) antenna is provided for emitting electromagnetic radiation. The antenna includes a base, a pair of brackets, a pair of spars, a plurality of waveguides, and a radome. The base provides longitudinal and lateral support for the antenna on a platform. The brackets are disposed at longitudinally opposite ends on the base. The spars connect the brackets and are disposed at laterally opposite ends of the base. The waveguides are disposed in stagger array. Each waveguide has a pair of broad walls and a pair of side walls that share longitudinal edges. The broad wall is wider than the side wall. The broad wall includes elliptical slots penetrating each waveguide. The stagger array arranges first and second waveguides share respective first and second longitudinal edges. The radome covers the waveguides and connects to the pair of spars. |
| FILED | Monday, December 12, 2022 |
| APPL NO | 18/079585 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/42 (20130101) H01Q 21/0056 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034276 | Lyakh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | Arkadiy Lyakh (Oviedo, Florida); Matthew Suttinger (Orlando, Florida) |
| ABSTRACT | A QCL may include a substrate, and a sequence of semiconductor epitaxial layers adjacent the substrate and defining an active region, an injector region adjacent the active region, and a waveguide optically coupled to the active region. The active region may include stages, each stage having an upper laser level and a lower laser level defining respective first and second wave functions. The upper laser level may have an upper laser level average coordinate, and the lower laser level may have a lower laser level average coordinate. The upper laser level average coordinate and the lower laser level average coordinate may have spacing of less than 10 nm. Wave functions for all active region energy levels located below the lower laser level may have greater than 10% overlap with the injector region. |
| FILED | Friday, October 07, 2022 |
| APPL NO | 17/938817 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/20 (20130101) H01S 5/22 (20130101) H01S 5/026 (20130101) H01S 5/3402 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034490 | Paudel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | Uttam Paudel (La Palma, California); Noel De La Cruz (Compton, California); Andrew K. Mollner (Los Angeles, California); Alexander Christidis (Whittier, California) |
| ABSTRACT | A reconfigurable QKD transceiver capable of transmitting and/or receiving qubits using a single optical hardware platform. This reconfigurable QKD transceiver enables various link scenarios specially for LEO-ground network, where the satellites have limited engagement time with a ground station. The reconfigurable QKD transceiver may reduce the optics SWaP by 50 percent and may allow for new mission scenarios that were otherwise not feasible with a transmitter only architecture or receiver only architecture. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/537962 |
| ART UNIT | 2635 — Optics |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/60 (20220101) Transmission H04B 10/40 (20130101) H04B 10/85 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0852 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034582 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Peraton Labs Inc. (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | Peraton Labs Inc. (Basking Ridge, New Jersey) |
| INVENTOR(S) | William Johnson (Basking Ridge, New Jersey); Kiran Rege (Basking Ridge, New Jersey); Achilles Kogiantis (Basking Ridge, New Jersey) |
| ABSTRACT | There is set forth herein, in one embodiment, receiving, by a transceiver of a UE device an aggregate signal stream, the aggregate signal stream including an aggregate of base station downlink signal streams from a plurality of base stations; processing the aggregate signal stream and detecting, from the processing of the aggregate signal stream, a set of base stations in communication range of the UE device, wherein the set of base stations include a current serving base station and a scanning base station; determining, from the processing of the aggregate signal stream, a Doppler shifted center frequency of a downlink scanning signal stream received from the scanning base station; and enhancing, in dependence on the Doppler shifted center frequency, the downlink scanning signal stream associated to the scanning base station. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/249590 |
| ART UNIT | 2413 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 7/088 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/2657 (20130101) Original (OR) Class Wireless Communication Networks H04W 48/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034747 | Raghavendra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ramya Raghavendra (New York, New York); Mudhakar Srivatsa (White Plains, New York); Joshua M. Rosenkranz (Westchester, New York); Christopher Streiffer (Metairie, Louisiana) |
| ABSTRACT | Data associated with performances of microservices functioning in a distributed computing environment is clustered by executing an unsupervised machine learning algorithm. A representative data is selected from a cluster, selecting performed for a plurality of the clusters. Based on time series data of the representative data associated with the plurality of the clusters, causal extraction is performed. Based on the causal extraction and the plurality of the clusters, a causal graph is constructed. The causal graph is embedded into vector space. Based on the embedded vector space, an artificial neural network model can be trained for managing the distributed computing environment. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/297013 |
| ART UNIT | 2496 — Computer Networks |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/088 (20130101) G06N 20/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12035106 | Lawson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | Aaron Lawson (San Jose, California); Mitchell L McLaren (Everton Park, Australia); Diego Castan Lavilla (Dobbs Ferry, New York) |
| ABSTRACT | In some examples, a system includes a storage device; and processing circuitry having access to the storage device. The processing circuitry is configured to receive information indicative of a media dataset, where the media dataset corresponds to an object; and analyze the media dataset to compute a corresponding set of operating condition weight values. Additionally, the processing circuitry is configured to compare the set of operating condition weight values corresponding to the media dataset with a plurality of sets of reference operating condition weight values that each correspond to a different reference media dataset of a plurality of reference media datasets; and determine, based on the comparison of the set of operating condition weight values with the plurality of sets of reference operating condition weight values, an indication of a capability of a trained machine learning model to correctly verify the object in the media dataset. |
| FILED | Friday, October 22, 2021 |
| APPL NO | 17/508365 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/214 (20230101) G06F 18/2185 (20230101) G06F 18/2413 (20230101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 25/453 (20130101) Original (OR) Class H04R 2225/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12035134 | Pratt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Thomas G. Pratt (South Bend, Indiana); Joseph Lawrence Loof (South Bend, Indiana); Eric Jesse (South Bend, Indiana) |
| ABSTRACT | Devices and techniques for authenticating wireless communications are disclosed. In some embodiments, the techniques can be performed by a network access point that includes a receiver to receive a wireless signal from a remote device. The network access point can also include a processor to calculate polarization data for the wireless signal and to determine whether the polarization data includes at least one characteristic that corresponds to a characteristic of a stored authenticated polarization signature. |
| FILED | Wednesday, June 19, 2019 |
| APPL NO | 17/126762 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Transmission H04B 7/10 (20130101) Wireless Communication Networks H04W 12/06 (20130101) Original (OR) Class H04W 12/79 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12035455 | Hegelich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Bjorn Manuel Hegelich (Austin, Texas); Constantin Aniculaesei (Austin, Texas) |
| ABSTRACT | Disclosed herein are particle-assisted wakefield electron acceleration devices, accelerated electrons generated using said devices, and methods of use thereof. |
| FILED | Tuesday, June 21, 2022 |
| APPL NO | 17/845223 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 15/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12029175 | Simmons et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Kevin L. Simmons (Kennewick, Washington); Stanley L Owsley, Jr. (Pasco, Washington); Dustin T. Clelland (Pasco, Washington) |
| ABSTRACT | Plant supplement delivery assemblies are provided that can include an insert having collapsible insert sidewalls complimentary to the exterior sidewalls of the delivery assembly housing, the collapsible insert sidewalls defining at least a portion of a container configured to house a plant supplement. A butt end of the insert can be configured to operably engage a biased member. Methods for providing plant supplements are also provided. The methods can include operably engaging a biased member with a butt end of a container to collapse sidewalls of the container and provide plant supplement from the container through a stem into a plant. Methods for recycling components of a plant supplement delivery assembly are also provided. The methods can include, after providing plant supplements from an insert of a plant supplement delivery assembly, removing the spent insert from the assembly and replacing the spent insert with a sealed insert. |
| FILED | Thursday, September 24, 2020 |
| APPL NO | 17/031391 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030000 | Baxter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sustainable Energy Solutions, Inc. (Provo, Utah) |
| ASSIGNEE(S) | Sustainable Energy Solutions, LLC (Ball Ground, Georgia) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); David Frankman (Provo, Utah); Skyler Chamberlain (Provo, Utah); Kyler Stitt (Lindon, Utah); Christopher Hoeger (Provo, Utah); Eric Mansfield (Spanish Fork, Utah); Andrew Baxter (Spanish Fork, Utah); Nathan Davis (Bountiful, Utah) |
| ABSTRACT | Devices, systems, and methods for separating solids from liquids are disclosed. A vessel includes an inlet, a carrier liquid outlet, a product outlet, a purifying section, and a heater. The inlet directs a slurry into the purifying section. The slurry comprises particles of a solid and a carrier liquid. The purifying section preferentially drives the particles of the solid towards a heating zone of the purifying section versus the carrier liquid. This displaces a first portion of the carrier liquid away from the heating zone of the purifying section. The heater heats the slurry. The carrier liquid outlet drives a majority of the carrier liquid out of the vessel. The product outlet is adjacent to the heating zone of the purifying section. |
| FILED | Friday, December 22, 2017 |
| APPL NO | 15/852674 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 17/02 (20130101) B01D 17/0214 (20130101) B01D 21/009 (20130101) Original (OR) Class B01D 21/10 (20130101) B01D 21/0024 (20130101) B01D 21/2405 (20130101) Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 3/08 (20130101) F25J 2205/02 (20130101) F25J 2205/20 (20130101) F25J 2220/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030017 | Bhave et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); All American Lithium LLC (Brawley, California) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); TERRALITHIUM LLC (Houston, Texas) |
| INVENTOR(S) | Ramesh R. Bhave (Knoxville, Tennessee); Vishwanath Deshmane (Painted Post, New York); Nicholas N. Linneen (Knoxville, Tennessee); Stephen Harrison (Benicia, California); Mariappan Paranthaman (Knoxville, Tennessee); Bruce A. Moyer (Oak Ridge, Tennessee); Syed Z. Islam (Oak Ridge, Tennessee) |
| ABSTRACT | A method of concentrating a lithium-containing aqueous solution, the method comprising: (i) providing a water-permeable structure having an inner surface and outer surface, wherein at least said outer surface is coated with a water-permeable hydrophilic polymer having a thermal stability of at least 100° C.; and (ii) flowing a lithium-containing aqueous feed solution having an initial concentration of lithium over said inner surface while said outer surface is in contact with an aqueous draw solution containing a higher overall ion concentration than said lithium-containing aqueous feed solution, to result in forward osmosis of water from said lithium-containing aqueous feed solution to said aqueous draw solution, and wherein said forward osmosis results in a lithium-containing aqueous product solution having an increased concentration of lithium relative to the initial concentration of lithium in the lithium-containing aqueous feed solution. |
| FILED | Thursday, August 08, 2019 |
| APPL NO | 16/535585 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/005 (20130101) Original (OR) Class B01D 61/0022 (20220801) B01D 69/04 (20130101) B01D 69/1216 (20220801) B01D 71/34 (20130101) B01D 71/36 (20130101) B01D 71/68 (20130101) B01D 71/5222 (20220801) B01D 2311/103 (20130101) B01D 2325/20 (20130101) B01D 2325/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030022 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Engi-Mat Co. (Lexington, Kentucky) |
| ASSIGNEE(S) | Engi-Mat Co. (Lexington, Kentucky) |
| INVENTOR(S) | David Wilson (Lexington, Kentucky); Haibing Wang (Phoenix, Arizona); Claudia Goggin (Lexington, Kentucky); Brian Mackey (Lexington, Kentucky) |
| ABSTRACT | Composite structures composed of inorganic membranes or polymer membranes supported on a multilayered woven wire mesh substrate are provided. Also provided are methods of making the composite structures and methods of using the composite structures as separation membranes. The mesh substrates are composed of a stack of two or more layers of woven wire mesh, wherein the different mesh layers in the stack have different mesh sizes. The multilayered mesh structure can support a defect-free, or substantially defect-free, membrane and has sufficient mechanical strength to allow the supported membranes to be used for chemical separations. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/183255 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/362 (20130101) B01D 61/363 (20220801) B01D 67/0039 (20130101) B01D 69/04 (20130101) B01D 69/108 (20220801) Original (OR) Class B01D 71/0281 (20220801) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/448 (20130101) C02F 2101/34 (20130101) Acyclic or Carbocyclic Compounds C07C 29/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030029 | Wegeng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Robert Wegeng (Richland, Washington); Paul H. Humble (Kennewick, Washington); Shankar Krishnan (Wilsonville, Oregon); Steven D. Leith (Albany, Oregon); Daniel R. Palo (Chisholm, Minnesota); Robert A. Dagle (Richland, Washington) |
| ABSTRACT | A solar thermochemical processing system is disclosed. The system includes a first unit operation for receiving concentrated solar energy. Heat from the solar energy is used to drive the first unit operation. The first unit operation also receives a first set of reactants and produces a first set of products. A second unit operation receives the first set of products from the first unit operation and produces a second set of products. A third unit operation receives heat from the second unit operation to produce a portion of the first set of reactants. |
| FILED | Tuesday, March 28, 2023 |
| APPL NO | 18/191141 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/127 (20130101) Original (OR) Class B01J 2219/00006 (20130101) B01J 2219/089 (20130101) B01J 2219/00159 (20130101) B01J 2219/0883 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/48 (20130101) C01B 3/384 (20130101) C01B 2203/061 (20130101) C01B 2203/0233 (20130101) C01B 2203/0283 (20130101) C01B 2203/0445 (20130101) C01B 2203/0855 (20130101) C01B 2203/1288 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 2/30 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 3/04 (20130101) Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 3/188 (20130101) Methods of Steam Generation; Steam Boilers F22B 1/006 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 20/20 (20180501) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0612 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/40 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/129 (20151101) Y02P 20/133 (20151101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) Y10T 137/8593 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030032 | Bai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ExxonMobil Technology and Engineering Company (Annandale, New Jersey); TDA Research, Inc. (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | ExxonMobil Technology and Engineering Company (Annandale, New Jersey); TDA Research, Inc. (Wheat Ridge, Colorado) |
| INVENTOR(S) | Chuansheng Bai (Phillipsburg, New Jersey); Majosefina Cunningham (Whitehall, Pennsylvania); Patrick P. McCall (Matawan, New Jersey); Hans Thomann (Bedminster, New Jersey); Jeannine Elizabeth Elliott (Superior, Colorado); Vinh Nguyen (Arvada, Colorado) |
| ABSTRACT | The disclosure generally relates to CCS sorbents, particularly for CO2/H2O displacement desorption process. The sorbents include an aluminum oxide support that includes alkali metal salts within the support, in the form of pseudo alkali aluminate. The sorbents also include alkali metal salt impregnated on the support. The sorbents demonstrate improved CO2 loadings and better H2O/CO2 ratios, as well as improved stability. Compositions and methods of making are disclosed. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/316713 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 2253/1124 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/08 (20130101) Original (OR) Class B01J 20/041 (20130101) B01J 20/3007 (20130101) B01J 20/3078 (20130101) B01J 20/3204 (20130101) B01J 20/3236 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 20/40 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030088 | Kumar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Sortera Alloys, Inc. (Forth Worth, Texas) |
| ASSIGNEE(S) | Sortera Technologies, Inc. (Markle, Indiana) |
| INVENTOR(S) | Nalin Kumar (Fort Worth, Texas); Manuel Gerardo Garcia, Jr. (Lexington, Kentucky) |
| ABSTRACT | A material sorting system sorts materials utilizing multiple stages of classification and sorting, including a vision system that implements a machine learning system in order to identify or classify each of the materials, and Laser Induced Breakdown Spectroscopy to perform a subsequent classification and sorting of the remaining materials. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673694 |
| ART UNIT | 3653 — Optics |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 5/04 (20130101) B07C 5/34 (20130101) B07C 5/342 (20130101) B07C 5/3422 (20130101) Original (OR) Class B07C 2501/0054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030120 | Conner et al. |
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| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Brett Page Conner (Lee's Summit, Missouri); Benjamin Ross Brown (Lee's Summit, Missouri) |
| ABSTRACT | A system and method of testing a part manufactured using an additive manufacturing process. The part may be excited via an input mechanism that imparts an excitation force on the part to induce a dynamic response in the part. An output mechanism may be used to sense the dynamic response in the part. A processing element may be used to compare the dynamic response with a reference to identify an indication of excess powder in the part. |
| FILED | Thursday, December 02, 2021 |
| APPL NO | 17/540926 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/68 (20210101) Original (OR) Class B22F 12/90 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030789 | Xiao et al. |
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| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington); Albemarle Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington); Albemarle Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Jie Xiao (Richland, Washington); Ran Yi (Richland, Washington); Yujing Bi (Richland, Washington); Job T. Rijssenbeek (Lake Wylie, South Carolina); Xiaoguang Hao (Fremont, California); Subramanian Venkatachalam (Charlotte, North Carolina); Liu Luo (Belmont, North Carolina) |
| ABSTRACT | Methods for synthesizing crystalline Ni-rich cathode materials are disclosed. The Ni-rich cathode material may have a formula LiNixMnyMzCo1-x-y-zO2, where M represents one or more dopant metals, x≥0.6, 0.01≤y<0.2, 0≤z≤0.05, and x+y+z≤1.0. The methods are cost-effective, and include methods for solid-state, molten-salt, and flash-sintering syntheses. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 17/523734 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/50 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2006/40 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 2004/021 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030843 | Sadow et al. |
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| FUNDED BY |
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| APPLICANT(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| ASSIGNEE(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
| INVENTOR(S) | Aaron David Sadow (Ames, Iowa); Uddhav Kanbur (Ames, Iowa) |
| ABSTRACT | Disclosed herein is a process for the conversion of polymers, oligomers, or mixtures thereof into shorter alkanes, carboxylic acids, alcohols, alkyl halides or aldehydes. This process includes contacting the polymers, oligomers, or mixtures thereof with the compound of formula (I): Al(R1)3 (I) where R1 is independently selected at each occurrence thereof from the group consisting of H, aryl, C1-C8 alkyl, and C1-C8 alkoxy, as a reaction mixture, in the presence of a catalyst selected from the group consisting of a transition metal catalyst, a lanthanide series metal catalyst, or combinations thereof. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 17/554666 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/12 (20130101) B01J 31/143 (20130101) B01J 31/1616 (20130101) Acyclic or Carbocyclic Compounds C07C 4/06 (20130101) Original (OR) Class C07C 17/06 (20130101) C07C 29/50 (20130101) C07C 41/01 (20130101) C07C 45/455 (20130101) C07C 51/15 (20130101) C07C 67/24 (20130101) C07C 231/02 (20130101) C07C 2521/12 (20130101) C07C 2531/16 (20130101) C07C 2531/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030969 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Chen Wang (Superior, Colorado); Gregg Tyler Beckham (Golden, Colorado); Nicholas A. Rorrer (Golden, Colorado) |
| ABSTRACT | The present disclosure relates to a resin that includes a first repeat unit as defined by Structure (I) where A is either a methyl group or a hydrogen atom, R1 is a first bridging group, and |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/371421 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 216/36 (20130101) Original (OR) Class C08F 236/14 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/14 (20130101) C08J 2367/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030981 | Kohl et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Paul A. Kohl (Atlanta, Georgia); Garrett Huang (Atlanta, Georgia); Mrinmay Mandal (Atlanta, Georgia) |
| ABSTRACT | The invention relates to an anion-exchange membrane (AEM) having a multiblock copolymer including a hydrophilic norbornene-based monomer and a hydrophobic alkene-based or norbornene-based monomer. The hydrophilic norbornene-based monomers include one or more cationic head groups such as a quaternary ammonium ion, which can optionally be crosslinked with a crosslinking agent to increase the structural stability of the polymer. These AEMs can be employed in electrochemical devices such as fuel cells. |
| FILED | Wednesday, March 27, 2019 |
| APPL NO | 17/042003 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/14 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/08 (20130101) Original (OR) Class C08G 2261/12 (20130101) C08G 2261/135 (20130101) C08G 2261/146 (20130101) C08G 2261/3324 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/2256 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 50/414 (20210101) H01M 50/497 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031029 | Gray et al. |
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| FUNDED BY |
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| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Mcmahan L. Gray (Pittsburgh, Pennsylvania); Brian W. Kail (Pittsburgh, Pennsylvania); Walter C. Wilfong (Jefferson Hills, Pennsylvania); Qiuming Wang (South Park, Pennsylvania) |
| ABSTRACT | Materials, methods of making, and methods of using a stable and regenerable immobilized amine sorbents for rare earth element and heavy metal recovery from liquid sources. Embodiments of the invention relate to the novel combination of different polyamines, primarily polyethylenimine Mw=800 (PEI800), and an epoxysilane, namely 2-(3,4-epoxycyclohexyl)ethyltrimethoxysilane (ECTMS), covalently immobilizing theREE and heavy metal-adsorbing amine sites within low cost, porous silica particles. |
| FILED | Tuesday, November 22, 2022 |
| APPL NO | 17/992617 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 2252/20415 (20130101) B01D 2257/60 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 11/005 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0812 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/0206 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) C08K 5/5419 (20130101) C08K 7/14 (20130101) Compositions of Macromolecular Compounds C08L 79/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031210 | Miller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | John S. Miller (Walnut Creek, California); Selim Elhadj (Livermore, California); Thomas M. Spinka (Livermore, California) |
| ABSTRACT | A method is disclosed for doping a quantity of powder particles. A container having a central chamber is initially charged with a quantity of powder particles. A quantity of precursor is sublimed to form a heated precursor. A quantity of carrier gas is mixed with the precursor to form a mixture of heated precursor/carrier gas. The central chamber is charged with the heated precursor/carrier gas and then moved to cause interaction of the powder particles with the heated precursor/carrier gas to form a first monolayer coating on the powder particles. The heated precursor/carrier gas is then removed from the central chamber and the central chamber is charged with a O2/O3 gas under a plasma. The central chamber is then further moved to produce interaction of the O2/O3 gas with the first monolayer coating on the powder particles to modify the first monolayer coating to create a different, single monolayer coating forming an oxide coating on the powder particles. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988217 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/45536 (20130101) C23C 16/45544 (20130101) C23C 16/45553 (20130101) C23C 16/45555 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031380 | Figley |
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| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Reed Richard Figley (Los Alamos, New Mexico) |
| ABSTRACT | A lockout tool assembly for locking open a roll-up door that automatically closes without power is provided. A lockout tool assembly may include a lockout tool member, a first lockout plate, and a second lockout plate. The lockout plate may each define a receiving recess, such that when the first lockout plate and the second lockout plate are installed inverse to one another in a closed lockout alignment position, the receiving recesses are complementary in that they form a crossbar restraint receiving aperture. Methods for locking open a roll-up door with such lockout tool assemblies and for removing installed lockout tool assemblies are also provided. |
| FILED | Monday, November 20, 2023 |
| APPL NO | 18/514604 |
| ART UNIT | 3634 — Static Structures, Supports and Furniture |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/80 (20130101) Original (OR) Class E06B 2009/802 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031566 | Joshi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Vineet V. Joshi (Richland, Washington); Sina Shahrezaei (Richland, Washington); Curt A. Lavender (Richland, Washington); Rob J. Seffens (Kennewick, Washington); Mark A. Rhodes (Kennewick, Washington); Darrell R. Herling (Kennewick, Washington); Aashish Rohatgi (Richland, Washington) |
| ABSTRACT | Riveted assemblies are provided that can include: a first component having opposing first and second sidewalls; a second component having opposing third and fourth sidewalls, wherein the second sidewall of the first component abuts the third sidewall of the second component to bind and form an affixing interface comprising the second and third sidewall between the first component to the second component; and a rivet extending between a head along a shank to an end, the rivet piercing the first sidewall with the end of the rivet being between the first and fourth sidewalls. Methods for affixing at least two components using a rivet are also provided. The methods can include: providing a first component having opposing first and second sidewalls; providing a second component having opposing third and fourth sidewalls; abutting the second sidewall of the first component to the third sidewall of the second component; providing a rivet extending between a head along a shank to an end; projecting the rivet through at least the first sidewall of the first component to form an affixing interface comprising the second and third sidewalls. |
| FILED | Thursday, May 12, 2022 |
| APPL NO | 17/743413 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Forging; Hammering; Pressing Metal; Riveting; Forge Furnaces B21J 15/025 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/04 (20130101) Original (OR) Class F16B 19/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031777 | Bahar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xergy, Inc. (Harrington, Delaware) |
| ASSIGNEE(S) | FFI IONIX IP, INC. (Wilmington, Delaware) |
| INVENTOR(S) | Bamdad Bahar (Georgetown, Delaware); Jacob Zerby (Dover, Delaware); Harish Opadrishta (Dover, Delaware); Jason Woods (Boulder, Colorado); Xiaobing Liu (Knoxville, Tennessee) |
| ABSTRACT | A tube-in-tube heat exchanger utilizes a selectively permeable tube having a selective permeable layer to allow the refrigerant to transfer into an ionic liquid to generate heating or cooling. The ionic liquid then provides heating or cooling to a heat transfer fluid through a non-permeable layer or tube. The system may be configured as a shell and tube design, with the third fluid free to flow on the outside of the shell, or as a shell and tube-in-tube, with a central tube containing a first liquid, a second tube containing a second liquid, and an outer shell containing the third liquid. The selectively permeable tube may include an anion or cation selectively permeable layer and this layer may be supported by a support layer or tube. |
| FILED | Monday, September 26, 2022 |
| APPL NO | 17/953277 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 15/14 (20130101) F25B 37/00 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 7/103 (20130101) F28D 20/003 (20130101) F28D 21/0015 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12032116 | Bowman et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Daniel Bowman (Corrales, New Mexico); Jerry Rouse (Virginia Beach, Virginia); Siddharth Krishnamoorthy (Pasadena, California); Attila Komjathy (La Crescenta, California); James Cutts (Pasadena, California) |
| ABSTRACT | Various embodiments described herein provide for a balloon-borne aeroseismometer that can detect infrasonic signals and concurrent vibrations caused by the infrasonic signals. Through a set of motion sensors that can detect acceleration in three planes, the aeroseismometer can determine the direction of vibration and thus determine a travel path of the infrasonic signal relative to the aeroseismometer. The aeroseismometer can also translate the direction of the source from a reference frame of the aeroseismometer to an external reference frame, such as a planetary coordinate system, in order to identify potential locations of a source of the infrasonic signals. |
| FILED | Monday, March 14, 2022 |
| APPL NO | 17/694062 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Lighter-than Air Aircraft B64B 1/40 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/01 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/01 (20240101) G01V 7/16 (20130101) Meteorology G01W 1/08 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12032199 | Panas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Bright Silicon Technologies, Inc. (San Francisco, California); Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); Bright Silicon Technologies, Inc. (San Francisco, California); Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Robert Matthew Panas (Dublin, California); Robert S. Mchenry (San Francisco, California); Gerald P. Uyeno (Tucson, Arizona) |
| ABSTRACT | The present disclosure relates to an optical sensor protection system. The system may have a sensor for receiving an incoming optical signal, a passive sensing and modulation component, and an active sensing and modulation subsystem. The passive sensing and modulation component is configured to sense when a first characteristic is associated with the incoming optical signal is present that adversely affects operation of the sensor, and redirects at least a portion of the incoming optical signal thereof away from the sensor to thus reduce an intensity of the incoming optical signal reaching the sensor. The sensor is located on an image plane downstream of the ISM subsystem, relative to a path of travel of the incoming optical signal. The active sensing and modulation subsystem has an active modulation component and is located upstream of the passive sensing and modulation component, relative to the path of travel of the incoming optical signal, and is also located on a conjugate image plane, and is configured to use the redirected portion of the incoming optical signal as feedback in controlling a modification of the incoming optical signal to reduce a risk of damage to the passive sensing and modulation component. |
| FILED | Wednesday, April 20, 2022 |
| APPL NO | 17/725030 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/0031 (20130101) G02B 6/0093 (20130101) Original (OR) Class G02B 6/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12033051 | Blake et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Robert C. Blake (Mountain House, California); Thomas J. O'Hara (Alameda, California); Mikel L. Landajuela (Dublin, California); Rushil Anirudh (Dublin, California) |
| ABSTRACT | A computer-based system and process are disclosed for reconstructing the internal electrical behavior of a patient's heart based partly or wholly on the patient's electrocardiogram (ECG). The output of the process may include, for example, a cardiac activation map, and/or a representation of transmembrane potentials over time. The process advantageously does not require any medical imaging of the patient, and does not require any special medical equipment. For example, the patient's activation map and transmembrane potentials may be reconstructed based solely on a preexisting or newly-obtained 12-lead cardiac ECG of the patient. The process makes use of a machine learning model, such as a neural network based model, trained with actual and/or simulated ECGs and intracardiac electrical data (typically transmembrane potentials) of many thousands of patients. Because an insufficient quantity of such data exists for actual patients, model training may be performed using ECGs and intracardiac electrical data obtained through computer simulations. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/103624 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/327 (20210101) A61B 5/367 (20210101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Original (OR) Class G06N 3/08 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12033714 | Jayasena et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
| INVENTOR(S) | Nuwan S. Jayasena (Santa Clara, California); Yasuko Eckert (Bellevue, Washington) |
| ABSTRACT | A processing system includes a plurality of processor cores formed in a first layer of an integrated circuit device and a plurality of partitions of memory formed in one or more second layers of the integrated circuit device. The one or more second layers are deployed in a stacked configuration with the first layer. Each of the partitions is associated with a subset of the processor cores that have overlapping footprints with the partitions. The processing system also includes first memory paths between the processor cores and their corresponding subsets of partitions. The processing system further includes second memory paths between the processor cores and the partitions. |
| FILED | Wednesday, April 07, 2021 |
| APPL NO | 17/224603 |
| ART UNIT | 2136 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0811 (20130101) G06F 12/0815 (20130101) G06F 12/0888 (20130101) G06F 2212/251 (20130101) G06F 2212/254 (20130101) G06F 2212/502 (20130101) G06F 2212/1016 (20130101) Static Stores G11C 5/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12033846 | Gaowei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Department of Energy (Washington, District of Columbia) |
| ASSIGNEE(S) | U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Mengjia Gaowei (Stony Brook, New York); John Smedley (White Rock, New Mexico); John Walsh (Upton, New York); Jiajie Cen (San Jose, California); John Jay Sinsheimer (Centereach, New York) |
| ABSTRACT | One or more embodiments relates to a system and method for growing ultrasmooth and high quantum efficiency photocathodes. The method includes exposing a substrate of Si wafer to an alkali source; controlling co-evaporating growth and co-deposition forming a growth including Te; and monitoring a stoichiometry of the growth, forming the photocathodes. |
| FILED | Thursday, October 15, 2020 |
| APPL NO | 17/071501 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 19/007 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/06 (20130101) C23C 14/24 (20130101) C23C 14/52 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 9/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034050 | Esteves et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Giovanni Esteves (Albuquerque, New Mexico); Travis Ryan Young (Albuquerque, New Mexico) |
| ABSTRACT | An aluminum-scandium (Al—Sc) etch stop that is both CMOS compatible and highly conductive, and a method for forming the same are disclosed. The low volatility of Sc in Cl and strong covalent bond between Al—Sc leads to an increase in resistance to NaCl corrosion and makes it difficult to dry etch in Cl-based chemistries, resulting in an excellent etch stop material, especially when used in conjunction with an overlying aluminum nitride (AlN) or aluminum scandium nitride (AlScN) piezoelectric layer. When deposited at high deposition temperatures or when subsequently annealed at >600° C., the Al—Sc has a low resistivity, enabling corresponding device operation at temperatures up to at least 500° C. While Al3Sc is the preferred composition, Al1-xScx with x between 5 and 100 atomic percent provides many of these same benefits but comes at the cost of increased electrical resistivity and etch resistance with increasing Sc content due to Sc oxidation. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/391415 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0332 (20130101) H01L 21/30612 (20130101) H01L 29/2003 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/12764 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034116 | Visco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Vitaliy Nimon (San Francisco, California); Valentina Loginova (Walnut Creek, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California) |
| ABSTRACT | Battery component structures and manufacturing methods for solid-state battery cells include a unitary Li ion conducting sulfide glass solid electrolyte structure that serves as the basic building block around which a solid-state battery cell can be fabricated. The unitary glass structure approach can leverage precision controlled high throughput processes from the semiconductor industry that have been inventively modified as disclosed herein for processing a sulfide glass solid electrolyte substrate into a unitary Li ion conducting glass structure, for example, by using etching and lithographic photoresist formulations and methods. The glass substrate may be precision engineered to effectuate a dense glass portion and a porous glass portion that can be characterized as sublayers having predetermined thicknesses. The porous glass sublayer includes a plurality of discrete substantially vertical closed-end holes or trenches that are precision engineered into one or both major substrate surfaces using microfabrication processes. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/303706 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 15/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034376 | Lai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| ASSIGNEE(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia) |
| INVENTOR(S) | Jih-Sheng Lai (Blacksburg, Virginia); Chih-Shen Yeh (Blacksburg, Virginia) |
| ABSTRACT | Aspects of hybrid modulation control for DC-to-AC converters are described. In one embodiment, a hybrid modulation pattern is generated. The hybrid modulation pattern separates switch gating control into multiple control regions for a half cycle of the waveform. A first control region modulates according to a first modulation technique and a second control region modulates according to a second modulation technique. The switches of a resonant converter are controlled according to the hybrid modulation pattern to generate the waveform. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/765611 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/08 (20130101) H02M 1/0058 (20210501) H02M 3/01 (20210501) H02M 3/33573 (20210501) Original (OR) Class H02M 3/33576 (20130101) H02M 7/5387 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034422 | Doty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Fred Patrick Doty (Livermore, California); Bryant R. Morgan (Stockton, California); Isaac C. Avina (Brentwood, California) |
| ABSTRACT | A micro-structured device that can improve sensitivity and signal-to-noise for electronic sensor materials is embedded in electrically resistive materials. The technology includes a three-dimensional embedded electrode structure and fabrication methods for making the device for electronic sensing in bulk resistive materials. Embedded electrode structures address issues in conventional sensors by allowing independent control of sensitive material thickness, area, electric field intensity, and field direction. |
| FILED | Thursday, September 16, 2021 |
| APPL NO | 17/477160 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 3/0072 (20130101) Original (OR) Class H03H 2003/0428 (20130101) H03H 2003/0457 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12029674 | Kazerooni et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | suitX, Inc. (Emeryville, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); suitX, Inc. (Emeryville, California) |
| INVENTOR(S) | Homayoon Kazerooni (Berkeley, California); Wayne Tung (Berkeley, California); Michael McKinley (Berkeley, California); Yoon Jung Jeong (Berkeley, California) |
| ABSTRACT | An exoskeleton includes two torque generators, thigh links, and a supporting trunk rotatably coupled to the thigh links. When a wearer bends forward in the sagittal plane such that the supporting trunk extends beyond a predetermined angle A with respect to vertical, at least one of the torque generators imposes a resisting torque between the supporting trunk and a corresponding thigh link, thus imposing a force onto a wearer's trunk and thighs to aid in supporting the wearer in a bent position. The torque generators may be active or passive torque generators. When the supporting trunk does not extend beyond the predetermined angle A, the torque generators do not impose resisting torques between the supporting trunk and thigh links during the entire range of motion of the thigh links, thus enabling a wearer to walk, run, and sit without constraint while in a substantially upright position. |
| FILED | Thursday, April 04, 2019 |
| APPL NO | 16/375231 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/01 (20130101) A61F 5/02 (20130101) Original (OR) Class Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
12029816 — Compositions and methods of making brittle-matrix particles through blister pack freezing
| US 12029816 | Johnston et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Keith P. Johnston (Austin, Texas); Joshua Engstrom (Spotswood, New Jersey); Jasmine Rowe (Austin, Texas); Alan B. Watts (Plainsboro, New Jersey); Robert O. Williams, III (Austin, Texas) |
| ABSTRACT | The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane droplets upon atomization and the templated floc compacts upon the evaporation of the hydrofluoroalkane propellant to form a porous particle for deep lung delivery. |
| FILED | Tuesday, May 17, 2022 |
| APPL NO | 17/746915 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/008 (20130101) Original (OR) Class A61K 9/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12029826 | Westerhoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Paul K. Westerhoff (Scottsdale, Arizona); Zhe Zhao (Tempe, Arizona); Nora Shapiro (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Paul K. Westerhoff (Scottsdale, Arizona); Zhe Zhao (Tempe, Arizona); Nora Shapiro (Tempe, Arizona) |
| ABSTRACT | A coated optical fiber includes an optical fiber having a core and an outer surface, and a homogeneous polymer coating in contact with the outer surface of the optical fiber. The optical fiber and the homogeneous polymer coating are UV transparent, and a refractive index of the outer surface of the optical fiber or the homogeneous polymer coating is up to 15% less than a refractive index of the core. Coating the optical fiber includes coating an outer surface with a polymerizable material and polymerizing the polymerizerable material to yield the coated optical fiber having a homogeneous polymer coating. The optical fiber and the homogeneous polymer coating are UV transparent, and a refractive index of the outer surface of the optical fiber or the homogeneous polymer coating is up to 15% less than a refractive index of a core of the optical fiber. |
| FILED | Tuesday, February 08, 2022 |
| APPL NO | 17/667283 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) Original (OR) Class A61L 2202/11 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 25/105 (20130101) C03C 25/305 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 147/00 (20130101) Optical Elements, Systems, or Apparatus G02B 6/001 (20130101) G02B 6/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030020 | Jun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Young-Shin Jun (St. Louis, Missouri); Srikanth Singamaneni (St. Louis, Missouri); Xuanhao Wu (St. Louis, Missouri); Qisheng Jiang (St. Louis, Missouri) |
| ABSTRACT | A photothermal distillation membrane including a polydopamine (PDA) coated, polyvinylidene fluoride (PVDF) membrane is disclosed, as well as a process for synthesizing same. A photothermal aerogel membrane including a polydopamine (PDA)-containing bacterial nanocellulose (BNC) is also disclosed, as well as a process for synthesizing same. |
| FILED | Wednesday, June 07, 2023 |
| APPL NO | 18/330673 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/3641 (20220801) B01D 67/00933 (20220801) Original (OR) Class B01D 69/02 (20130101) B01D 69/12 (20130101) B01D 69/144 (20130101) B01D 71/34 (20130101) B01D 2325/38 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030081 | Park et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Jiwoong Park (Chicago, Illinois); Yu Zhong (Chicago, Illinois); Baorui Cheng (Chicago, Illinois) |
| ABSTRACT | Disclosed herein are inventive methods of making thin films, inventive thin films, and inventive articles and systems comprising thin films. Certain embodiments are related to methods of making thin films in which reagents are arranged within a first phase and a second phase such that at least one reagent reacts to form a thin film proximate to the interface between the first phase and the second phase. Thin films (including two-dimensional materials) disclosed herein can have one or more of a variety of beneficial properties including large lateral dimension(s), lateral continuity, high mechanical strength, consistent spatial composition, and/or consistent thickness. In accordance with certain embodiments, thin films disclosed herein can be combined to form a variety of inventive multi-layer articles, including multi-layer articles comprising a combination of thin films having different compositions that interact with each other via van der Waals forces. |
| FILED | Tuesday, October 06, 2020 |
| APPL NO | 17/767125 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/20 (20130101) B05D 1/185 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030085 | Rakich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Peter Rakich (New Haven, Connecticut); Prashanta Kharel (Cambridge, Massachusetts); William Renninger (Rochester, New York); Ryan Orson Behunin (Flagstaff, Arizona) |
| ABSTRACT | Techniques are provided to optomechanically couple light to a crystal structure, thereby producing stable, coherent bulk acoustic modes within the structure. In some embodiments, a resonator may comprise a plano-convex crystal structure to which pump light may be applied. The pump light may transfer energy to acoustic phonon modes of the crystal structure so as to create acoustic phonon modes with a coherence length greater than a length of the crystal structure. High frequency and high quality factor resonators may thereby be produced and operated. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 16/488223 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/04 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/11 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 15/00 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/08059 (20130101) Amplifiers H03F 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030210 | Minary-Jolandan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Majid Minary-Jolandan (Dallas, Texas); Mohammadreza Mahmoudi (Dallas, Texas); Scott R. Burlison (Fredericksburg, Texas); Chao Wang (Plano, Texas); Salvador Moreno (Dallas, Texas) |
| ABSTRACT | Scalable 3D-printing of ceramics includes dispensing a preceramic polymer at the tip of a moving nozzle into a gel that can reversibly switch between fluid and solid states, and subsequently thermally cross-linking the entire printed part “at-once” while still inside the same gel. The solid gel, including mineral oil and silica nanoparticles, converts to fluid at the tip of the moving nozzle, allows the polymer solution to be dispensed, and quickly returns to a solid state to maintain the geometry of the printed polymer both during printing and the subsequent high temperature (160° C.) cross-linking. The cross-linked part is retrieved from the gel and converted to ceramic by high temperature pyrolysis. This scalable process opens new opportunities for low-cost, high-speed production of complex 3-dimensional ceramic parts, and will be widely used for high temperature and corrosive environment applications, including electronics and sensors, microelectromechanical systems, energy, and structural applications. |
| FILED | Monday, June 21, 2021 |
| APPL NO | 17/304443 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/571 (20130101) C04B 35/589 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030839 | Dinca et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Mircea Dinca (Belmont, Massachusetts); Constanze Nicole Neumann (Somerville, Massachusetts) |
| ABSTRACT | Compositions and methods of use related to metal organic frameworks (MOFs) and/or nanoparticles are generally described. In some embodiments, methods and compositions for the catalytic upgrading of alcohols using MOFs and/or nanoparticles associated with MOFs are generally described. In some embodiments, a catalytic MOF composition is provided, wherein the MOF composition comprises a MOF compound and a plurality of metal catalytic compounds. In some embodiments, an alcohol may be exposed to the MOF composition and/or a plurality of nanoparticles associated with the MOF composition such that the alcohol is converted to a higher order alcohol. Advantageously, in some embodiments, the alcohol conversion occurs at a relatively high turnover frequency and/or with a relatively high selectivity as compared to traditional methods for converting alcohols. |
| FILED | Monday, November 30, 2020 |
| APPL NO | 17/106345 |
| ART UNIT | 1738 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/46 (20130101) B01J 31/1691 (20130101) B01J 2231/46 (20130101) B01J 2531/0208 (20130101) B01J 2531/821 (20130101) B01J 2531/845 (20130101) B01J 2531/847 (20130101) Acyclic or Carbocyclic Compounds C07C 29/16 (20130101) C07C 29/44 (20130101) Original (OR) Class C07C 31/12 (20130101) C07C 31/125 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/04 (20130101) C07F 15/06 (20130101) C07F 15/0046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030980 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jeremiah A. Johnson (Boston, Massachusetts); Peyton Shieh (Cambridge, Massachusetts); Keith Husted (Boston, Massachusetts); Christopher M. Brown (Boston, Massachusetts); Samantha Lynn Kristufek (Lubbock, Texas) |
| ABSTRACT | The present disclosure provides compositions comprising: a) a copolymer prepared by a method comprising polymerizing in the presence of a metathesis catalyst: i) a first monomer, wherein each instance of the first monomer is independently of the formula: or salt thereof; ii) a second monomer, wherein each instance of the second monomer is independently of the formula: or a salt thereof; iii) optionally a third monomer, wherein the third monomer is different from the first monomer and the second monomer; and iv) optionally a reprocessing catalyst; and b) optionally the reprocessing catalyst; wherein the reprocessing catalyst is a Brønsted acid, Lewis acid, Brønsted base, Lewis base, or a salt thereof; provided that the composition comprises at least one of the reprocessing catalyst of iv) and the reprocessing catalyst of b). The compositions may be reprocessed (e.g., remolded) under elevated temperature and/or elevated pressure. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/538098 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) Original (OR) Class C08G 61/12 (20130101) C08G 2261/70 (20130101) C08G 2261/314 (20130101) C08G 2261/418 (20130101) C08G 2261/3222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031008 | Zawko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Scott Zawko (Austin, Texas); Christine Schmidt (Gainesville, Florida) |
| ABSTRACT | The present invention includes a hydrogel and a method of making a porous hydrogel by preparing an aqueous mixture of an uncrosslinked polymer and a crystallizable molecule; casting the mixture into a vessel; allowing the cast mixture to dry to form an amorphous hydrogel film; seeding the cast mixture with a seed crystal of the crystallizable molecule; growing the crystallizable molecule into a crystal structure within the uncrosslinked polymer; crosslinking the polymer around the crystal structure under conditions in which the crystal structure within the crosslinked polymer is maintained; and dissolving the crystals within the crosslinked polymer to form the porous hydrogel. |
| FILED | Monday, July 31, 2023 |
| APPL NO | 18/361981 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 26/0023 (20130101) A61L 26/0095 (20130101) A61L 27/52 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0065 (20130101) Polysaccharides; Derivatives Thereof C08B 37/003 (20130101) C08B 37/0015 (20130101) C08B 37/0045 (20130101) C08B 37/0072 (20130101) C08B 37/0075 (20130101) C08B 37/0084 (20130101) Derivatives of Natural Macromolecular Compounds C08H 1/06 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 3/26 (20130101) C08J 3/28 (20130101) C08J 3/075 (20130101) C08J 3/242 (20130101) C08J 5/10 (20130101) C08J 5/18 (20130101) C08J 9/26 (20130101) Original (OR) Class C08J 2201/0424 (20130101) C08J 2205/04 (20130101) C08J 2205/022 (20130101) C08J 2207/10 (20130101) C08J 2305/00 (20130101) C08J 2305/04 (20130101) C08J 2305/08 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/21 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0025 (20130101) C08K 5/0083 (20130101) Compositions of Macromolecular Compounds C08L 5/00 (20130101) C08L 5/00 (20130101) C08L 5/00 (20130101) C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/06 (20130101) C08L 5/06 (20130101) C08L 5/08 (20130101) C08L 5/08 (20130101) C08L 5/10 (20130101) C08L 5/10 (20130101) C08L 5/10 (20130101) C08L 5/16 (20130101) C08L 89/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031075 | Caram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Justin Caram (Los Angeles, California); Stephanie Tenney (Los Angeles, California) |
| ABSTRACT | Many embodiments implement quantum confined nanoplatelets (NPLs) that can be induced to emit bright and tunable infrared emission from attached quantum dot (QD). Some embodiments provide mesoscale NPLs with a largest dimension of greater than 1 micron. Certain embodiments provide methods for growing mesoscale NPLs and QD on mesoscale NPLs heterostructures. Several embodiments provide near unity energy transfer from NPLs to QDs, which can quench NPL emission and emit with high quantum yield through the shortwave infrared. The QD defect emission can be kinetically tunable, enabling controlled mid-gap emission from NPLs. |
| FILED | Thursday, September 02, 2021 |
| APPL NO | 17/465444 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 11/00 (20130101) C01G 13/00 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/24 (20130101) C01P 2004/64 (20130101) C01P 2006/60 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/883 (20130101) C09K 11/892 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031121 | Yeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Daniel H. Yeh (Tampa, Florida); Ivy Lea Cormier Drexler (St. Petersburg, Florida); Melanie Pickett (Tampa, Florida); David Fulcher (Tampa, Florida) |
| ABSTRACT | In one embodiment, an algae cultivation system includes a basin that contains a liquid and a photobioreactor at least partially immersed in the liquid of the basin, the photobioreactor comprising a closed container including multiple panels that together define an interior space in which algae can be cultivated, at least one of the panels being transparent, the photobioreactor further comprising an inflatable float associated with the container that can be filled with a gas to change one or both of the position and orientation of the container within the liquid. |
| FILED | Monday, October 03, 2022 |
| APPL NO | 17/959263 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/22 (20130101) C12M 23/50 (20130101) C12M 29/04 (20130101) C12M 29/20 (20130101) C12M 31/08 (20130101) C12M 41/32 (20130101) C12M 41/40 (20130101) C12M 41/46 (20130101) C12M 41/48 (20130101) C12M 47/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031919 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Peng Jiang (Gainesville, Florida); Zhuxiao Gu (Gainesville, Florida); Sin-Yen Leo (Gainesville, Florida) |
| ABSTRACT | Described are chromogenic sensors, methods of use, and kits including sensors. The sensors can have a polymer structure with a waveform cross-section in a programmed state. Upon exposure to a first liquid, the polymer structure in the programmed state changes to polymer structure in an activated state. Methods for measuring the presence of a liquid using the sensor are described, as are kits including the sensors. |
| FILED | Thursday, September 01, 2022 |
| APPL NO | 17/901286 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12032190 | Kotov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Nicholas A. Kotov (Ypsilanti, Michigan); Sharon Glotzer (Chelsea, Michigan); Brian Shahbazian (Petaluma, California); Ryan Branch (Indianapolis, Indiana); Lizhi Xu (Ann Arbor, Michigan); Wonjin Choi (Ann Arbor, Michigan); Minjeong Cha (Ann Arbor, Michigan); Matthew Spellings (Mercer, Tennessee) |
| ABSTRACT | Material-Sensing Light Imaging, Detection, And Ranging (LIDAR) systems optionally include a laser configured to generate a light pulse, a beam steerer configured to produce a polarization-adjusted light pulse emitted towards an object, at least one polarizer configured to polarize reflected, scattered, or emitted light returned from the object, and a processor configured to detect at least one material of the object based on an intensity and polarization of the polarized reflected, scattered or emitted light from the object. The beam steerer may include a kirigami nanocomposite. Methods are also provided, including, for example, generating a light pulse, adjusting a polarization of the light pulse to produce a polarization-adjusted light pulse emitted towards an object, polarizing reflected, scattered, or emitted light returned from the object, and detecting at least one material of the object based on an intensity and polarization of the polarized reflected, scattered or emitted light from the object. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/231736 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/481 (20130101) G01S 17/89 (20130101) G01S 17/931 (20200101) Optical Elements, Systems, or Apparatus G02B 5/3025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12033533 | Kim |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Hong Suk Kim (San Jose, California) |
| ABSTRACT | Systems and methods in accordance with embodiments of the invention utilize technology to facilitate student question creation. Interactive platforms such as mobile phones or tablets can allow questions to be written, saved, and communicated electronically. In one embodiment, a method for collaboratively generating a question includes generating question data in response to input of a question and answer choices on a first device, sending the question data to a repository, sending the question data from the repository to a second device, displaying the question and answer choices on the second device, generating revised question data in response to input that changes the question, sending the revised question data to the repository, sending the revised question data to a third device, displaying the question and answer choices on the third device, receiving input of the selection of answer choices on the third device, and providing feedback whether the selection is correct. |
| FILED | Monday, December 02, 2019 |
| APPL NO | 16/700858 |
| ART UNIT | 2455 — Computer Networks |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/101 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 7/07 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 12/1827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034049 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Samsung Electronics Co., Ltd. (Suwon-si, South Korea); THE UNIVERSITY OF CHICAGO (Chicago, Illinois); Center for Technology Licensing at Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Samsung Electronics Co., Ltd. (Gyeonggi-do, South Korea); The University of Chicago (Chicago, Illinois); Center for Technology Licensing at Cornell University (Ithaca, New York) |
| INVENTOR(S) | Minhyun Lee (Suwon-si, South Korea); Jiwoong Park (Chicago, Illinois); Saien Xie (Ithaca, New York); Jinseong Heo (Seoul, South Korea); Hyeonjin Shin (Suwon-si, South Korea) |
| ABSTRACT | Provided are a superlattice structure including a two-dimensional material and a device including the superlattice structure. The superlattice structure may include at least two different two-dimensional (2D) materials bonded to each other in a lateral direction, and an interfacial region of the at least two 2D materials may be strained. The superlattice structure may have a bandgap adjusted by the interfacial region that is strained. The at least two 2D materials may include first and second 2D materials. The first 2D material may have a first bandgap in an intrinsic state thereof. The second 2D material may have a second bandgap in an intrinsic state thereof. An interfacial region of the first and second 2D materials and an adjacent region may have a third bandgap between the first bandgap and the second bandgap. |
| FILED | Wednesday, November 02, 2022 |
| APPL NO | 18/052017 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/158 (20130101) Original (OR) Class H01L 29/1054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034491 | Babakhani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Babak Jamali (Los Altos, California) |
| ABSTRACT | Systems and methods in accordance with embodiments of the invention implement electronic frequency-comb detector systems. One embodiment includes an electronic frequency-comb detector, where the electronic frequency-comb detector includes: a frequency-comb generator configured to generate a frequency comb reference signal, and a heterodyne mixer. In addition, the heterodyne mixer is configured to use the frequency comb reference signal to downconvert received millimeter wave (mm-wave) and terahertz (THZ) frequency tones into an intermediate frequency (IF) signal. In a further embodiment, the electronic frequency-comb detector includes an IF amplifier, where the IF amplifier is configured to feed a spectrum analyzer configured to detect a signature of a material under test (MUT). |
| FILED | Tuesday, January 28, 2020 |
| APPL NO | 17/426528 |
| ART UNIT | 2634 — Digital Communications |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 2203/56 (20130101) Transmission H04B 10/61 (20130101) H04B 10/90 (20130101) Original (OR) Class H04B 10/501 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 12029787 | Verardi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Paulo H. Verardi (Mansfield, Connecticut); Brittany Jasperse (Brick, New Jersey); Caitlin M. O'Connell (Glastonbury, Connecticut); Yuxiang Wang (Storrs, Connecticut) |
| ABSTRACT | Disclosed herein are methods for the rapid generation of recombinant poxviruses, for example, to enable vaccine development. |
| FILED | Thursday, July 01, 2021 |
| APPL NO | 17/365746 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/275 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2710/24034 (20130101) C12N 2710/24041 (20130101) C12N 2710/24051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031330 | Watkins |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ORB Technologies, LLC (Lexington, Kentucky) |
| ASSIGNEE(S) | ORB Technologies, LLC (Lexington, Kentucky) |
| INVENTOR(S) | Virginia Watkins (Lexington, Kentucky) |
| ABSTRACT | An apparatus for resisting a gravity load is disclosed. The apparatus has a first end member, a second end member, and a plurality of elongated structural members, each of the plurality of elongated structural members including a first end portion attached to the first end member and a second end portion attached to the second end member. The plurality of elongated structural members is oriented to resist compressive stresses or tensile stresses induced by the gravity load. The plurality of elongated structural members is formed from plants with a harvest cycle of four years or fewer. |
| FILED | Monday, April 17, 2023 |
| APPL NO | 18/301352 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Structural Elements; Building Materials E04C 2/16 (20130101) Original (OR) Class E04C 2/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031889 | Klemer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | K2 Biomicrosystems LLC (Geneva, Illinois) |
| ASSIGNEE(S) | K2 Biomicrosystems LLC (Geneva, Illinois) |
| INVENTOR(S) | David P. Klemer (Geneva, Illinois) |
| ABSTRACT | The present invention relates generally to the process of biological tissue and/or cellular disruption, and more particularly to an apparatus which can achieve such tissue and/or cellular disruption through the imposition of a time-varying electromagnetic field generated by electrical means and used to direct magnetic beads or other magnetic particles against a tissue sample. Tissue disruption is accomplished through mechanical impact between the magnetic particles and the sample biological tissue. |
| FILED | Monday, May 18, 2020 |
| APPL NO | 16/876562 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/508 (20130101) B01L 2400/043 (20130101) Apparatus for Enzymology or Microbiology; C12M 47/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/06 (20130101) C12N 1/066 (20130101) C12N 13/00 (20130101) C12N 15/10 (20130101) C12N 15/1003 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) Original (OR) Class G01N 1/4077 (20130101) G01N 27/44786 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031928 | Chin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AUBURN UNIVERSITY (Auburn, Alabama); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
| ASSIGNEE(S) | AUBURN UNIVERSITY (Auburn, Alabama); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
| INVENTOR(S) | Bryan A. Chin (Auburn, Alabama); Henry Allen Torbert, III (Opelika, Alabama); Galina N. Yakubova (Auburn, Alabama); Aleksandr Kavetskiy (Auburn, Alabama); Nikolay Sargsyan (Auburn, Alabama) |
| ABSTRACT | A system for analyzing soil content of a field includes a data acquisition unit configured to detect gamma spectra of each of a plurality of soil samples, wherein a surface area of the field is divided into a plurality of portions and the plurality of soil samples comprises at least one soil sample from each of the plurality of portions, a navigation unit configured to detect geographic coordinates of each of the plurality of soil samples, a data analysis unit configured to associate the detected gamma spectra of each of the plurality of soil samples with the geographic coordinates of the soil sample and determine a weight percent of at least one element within each of the soil samples based on the detected gamma spectra, and an element content map unit configured to generate a map indicating concentration of the at least one element within the soil of the field. |
| FILED | Thursday, June 16, 2022 |
| APPL NO | 17/841952 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Planting; Sowing; Fertilising A01C 21/007 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/22 (20130101) G01N 23/221 (20130101) G01N 23/222 (20130101) Original (OR) Class G01N 23/223 (20130101) G01N 2223/0745 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/22 (20240101) G01V 5/232 (20240101) G01V 5/234 (20240101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031983 | Irudayaraj et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Joseph Irudayaraj (Champaign, Illinois); Wen Ren (Urbana, Illinois) |
| ABSTRACT | The present disclosure relates to a novel method for lateral flow immunoassay (LFIA) by utilizing plasmonic enhancement strategy. More specifically, the present disclosure provides a plasmonic enhanced lateral flow sensor (pLFS) concept by introducing a liposome-based amplification of the colorimetric signals on the lateral flow platform for ultrasensitive detection of pathogens. |
| FILED | Friday, October 15, 2021 |
| APPL NO | 17/502320 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/521 (20130101) G01N 33/586 (20130101) G01N 33/587 (20130101) G01N 33/54388 (20210801) Original (OR) Class G01N 33/56916 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12035262 | Hollar |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wiser Systems, Inc. (Raleigh, North Carolina) |
| ASSIGNEE(S) | Wiser Systems, Inc. (Raleigh, North Carolina) |
| INVENTOR(S) | Seth Edward-Austin Hollar (Raleigh, North Carolina) |
| ABSTRACT | Methods for determining a location of an unknown device (UD) from a plurality of known devices (KDs) are provided including receiving, at the UD, periodically broadcasted messages from each of a plurality of KDs. Corresponding arrival time stamp (Tarrival-i-UD) of each periodically broadcasted message from each of the plurality of KDs are recorded. Each of the plurality of KDs are clock synchronized to a common clock source at a master device(MD). A departure time of the periodically broadcasted message from each of the plurality of KDs is known by the UD in master device time units (Tdepart-i-md). X, y and z coordinates of a location of each of the KDs is known by the UD. The x, y and z coordinates of an actual location of the UD is calculated using the x, y and z coordinates of each of the KDs, the recorded arrival times (Tarrival-i-UD) of each of the periodically broadcasted messages from each of the plurality of KDs and the known departure times of each of the periodically broadcasted messages (Tdepart-i-md) from each of the plurality of KDs. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/942273 |
| ART UNIT | 2414 — Multiplex and VoIP |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 5/00 (20130101) G01S 5/14 (20130101) G01S 5/021 (20130101) G01S 5/0218 (20200501) G01S 5/0263 (20130101) G01S 11/08 (20130101) Broadcast Communication H04H 20/18 (20130101) Wireless Communication Networks H04W 56/006 (20130101) H04W 56/007 (20130101) H04W 56/0015 (20130101) Original (OR) Class H04W 56/0025 (20130101) H04W 56/0065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12029230 | Kozubal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| INVENTOR(S) | Mark A. Kozubal (Bozeman, Montana); Richard E. Macur (Manhattan, Montana); Yuval C. Avniel (Missoula, Montana); Maximilian DeVane Hamilton (Bozeman, Montana) |
| ABSTRACT | Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. |
| FILED | Wednesday, September 13, 2023 |
| APPL NO | 18/367999 |
| ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1203 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/36 (20130101) Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/20 (20130101) A23J 3/227 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/065 (20160801) A23L 31/00 (20160801) Original (OR) Class A23L 33/195 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/208 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) C12M 23/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12030672 | Guzik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of Americas as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Allen T. Guzik (Strongsville, Ohio); Othmane Benafan (Fairview Park, Ohio); Yu Hin Hau (North Olmsted, Ohio); Linda H. Yoon (North Olmsted, Ohio); Chip Redding (Lakewood, Ohio) |
| ABSTRACT | A system and method for on-demand retention, release, and positioning of structures including space structures (e.g., solar panels, probes, antennae, scientific instruments, fairings, etc.). The system allows for a lightweight and reliable deployment mechanism utilizing shape memory alloy (SMA) technology that allows for structure transition from a stowed to a deployed configuration. SMAs are used for both the active actuation members (e.g., wires) and passive connecting members (e.g., hinges). The retention and release (R&R) mechanism includes the SMA actuator, a static and detachable plate, a pin puller, and retaining latches/hooks. Once released, the deployment and positioning mechanism consists of SMA preloaded hinges and latches. The innovative system and method may be used for deployment of CubeSat and smallsats solar panels, antennae, and the like where volume and power resources are very limited. The innovative system and method may also be used for deployment of components for other classes of small satellites. |
| FILED | Monday, September 25, 2017 |
| APPL NO | 15/714014 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/222 (20130101) Original (OR) Class B64G 1/443 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12032116 | Bowman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Daniel Bowman (Corrales, New Mexico); Jerry Rouse (Virginia Beach, Virginia); Siddharth Krishnamoorthy (Pasadena, California); Attila Komjathy (La Crescenta, California); James Cutts (Pasadena, California) |
| ABSTRACT | Various embodiments described herein provide for a balloon-borne aeroseismometer that can detect infrasonic signals and concurrent vibrations caused by the infrasonic signals. Through a set of motion sensors that can detect acceleration in three planes, the aeroseismometer can determine the direction of vibration and thus determine a travel path of the infrasonic signal relative to the aeroseismometer. The aeroseismometer can also translate the direction of the source from a reference frame of the aeroseismometer to an external reference frame, such as a planetary coordinate system, in order to identify potential locations of a source of the infrasonic signals. |
| FILED | Monday, March 14, 2022 |
| APPL NO | 17/694062 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Lighter-than Air Aircraft B64B 1/40 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/01 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 1/01 (20240101) G01V 7/16 (20130101) Meteorology G01W 1/08 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034770 | Kocsis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jin Kocsis (Lafayette, Indiana); Mututhanthrige Praveen Sameera Fernando (Akron, Ohio); Yifu Wu (Akron, Ohio) |
| ASSIGNEE(S) | The University of Akron (Akron, Ohio) |
| INVENTOR(S) | Jin Kocsis (Lafayette, Indiana); Mututhanthrige Praveen Sameera Fernando (Akron, Ohio); Yifu Wu (Akron, Ohio) |
| ABSTRACT | In one or more embodiments, the present invention is directed to a blockchain secured, software-defined network and monitoring system comprising: a multi-controller software-defined network (SDN) network layer; a blockchain based security and autonomy layer; a deep learning-driven decision making layer comprising the one or more computational centers and a horizontal data plane layer. In some embodiments, the present invention is directed to methods for ensuring the integrity of a control commands and optimizing performance and security using the blockchain secured, software-defined network and monitoring system. In various embodiments, the present invention relates to methods for extracting useful features from said labelled and non-labelled data contained in the horizontal data plane layer in the blockchain secured, software-defined network and monitoring system using a knowledge domain-enabled hybrid semi-supervision learning method. |
| FILED | Tuesday, November 19, 2019 |
| APPL NO | 17/297270 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/64 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/50 (20220501) H04L 9/3236 (20130101) H04L 9/3297 (20130101) H04L 41/20 (20130101) H04L 63/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12035151 | Barsoum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Constellation Designs, LLC (Wayne, Pennsylvania) |
| ASSIGNEE(S) | Constellation Designs, LLC (Wayne, Pennsylvania) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use unequally spaced constellations that have increased capacity compared to conventional constellations operating within a similar SNR band. One embodiment is a digital communications system including a transmitter transmitting signals via a communication channel, the transmitter including a coder capable of receiving user bits and outputting encoded bits at a rate, a mapper capable of mapping encoded bits to symbols in a constellation, and a modulator capable of generating a modulated signal for transmission via the communication channel using symbols generated by the mapper, wherein the constellation is unequally spaced and characterizable by assignment of locations and labels of constellation points to maximize parallel decode capacity of the constellation at a given signal-to-noise ratio so that the constellation provides a given capacity at a reduced signal-to-noise ratio compared to a uniform constellation that maximizes the minimum distance between constellation points of the uniform constellation. |
| FILED | Wednesday, May 19, 2021 |
| APPL NO | 17/325169 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/255 (20130101) H03M 13/6325 (20130101) Transmission H04B 15/00 (20130101) H04B 17/336 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 27/3405 (20130101) H04L 27/3483 (20130101) H04L 27/3809 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 12033111 | Wilson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | James Deforrest Wilson (Collierville, Tennessee) |
| ABSTRACT | Systems and methods of managing incorrectly addressed items in a distribution network. A user can identify via an interface items which are incorrectly labelled, addressed, or which identify an incorrect recipient. The distribution network can use information from the user to reprocess items, reroute items, or take other actions. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/062396 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 16/953 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/083 (20130101) G06Q 10/087 (20130101) G06Q 10/0833 (20130101) G06Q 10/0838 (20130101) Original (OR) Class G06Q 10/06315 (20130101) G06Q 10/08355 (20130101) G06Q 2250/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12033362 | Simpson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Ryan J. Simpson (Vienna, Virginia) |
| ABSTRACT | This application relates to a system for compressing captured images. The system may include an image capturing device configured to continuously capture images, for example, of a location, or frame, or field of view, and convert the captured images respectively into a plurality of sets of digital data, each of the plurality of sets of digital data including at least two consecutive rows of digital data. The system may also include a processor circuit configured to combine the at least two sets of the plurality of sets of digital data to generate a pre-compression set of digital data and simultaneously compress the pre-compression set of digital data simultaneously or together in a single compression operation. |
| FILED | Monday, July 31, 2023 |
| APPL NO | 18/362298 |
| ART UNIT | 2681 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/14 (20130101) Image Data Processing or Generation, in General G06T 7/13 (20170101) G06T 9/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12034853 | Bonnell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Clayton C. Bonnell (Fairfax, Virginia) |
| ABSTRACT | In some aspects, methods and systems for a digital trust architecture are provided. In some aspects, the architecture includes a user account provisioning process. The provisioning process may make use of in person verifications of some personal information to ensure authenticity of the user information. Once the authenticity of user information is established, an account may be created. The user account may include a user email account, with integrated access to digital certificates linked to the user account. Account creation may also automatically publish the new user's public key in a publicly accessible directory, enabling encrypted email information to be easily sent to the new user. |
| FILED | Monday, December 12, 2022 |
| APPL NO | 18/064729 |
| ART UNIT | 2498 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/6245 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/006 (20130101) H04L 9/32 (20130101) Original (OR) Class H04L 9/50 (20220501) H04L 9/0861 (20130101) H04L 9/3239 (20130101) H04L 9/3247 (20130101) H04L 9/3268 (20130101) H04L 63/123 (20130101) H04L 63/0442 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 12029230 | Kozubal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| ASSIGNEE(S) | The Fynder Group, Inc. (Chicago, Illinois) |
| INVENTOR(S) | Mark A. Kozubal (Bozeman, Montana); Richard E. Macur (Manhattan, Montana); Yuval C. Avniel (Missoula, Montana); Maximilian DeVane Hamilton (Bozeman, Montana) |
| ABSTRACT | Methods of production of edible filamentous fungal biomat formulations are provided as standalone protein sources and/or protein ingredients in foodstuffs as well as a one-time use or repeated use self-contained biofilm-biomat reactor comprising a container with at least one compartment and placed within the compartment(s), a feedstock, a fungal inoculum, a gas-permeable membrane, and optionally a liquid nutrient medium. |
| FILED | Wednesday, September 13, 2023 |
| APPL NO | 18/367999 |
| ART UNIT | 1791 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Dairy Products, e.g Milk, Butter, Cheese; Milk or Cheese Substitutes; Making Thereof A23C 9/1203 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/36 (20130101) Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 3/20 (20130101) A23J 3/227 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/065 (20160801) A23L 31/00 (20160801) Original (OR) Class A23L 33/195 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2250/208 (20130101) Apparatus for Enzymology or Microbiology; C12M 21/00 (20130101) C12M 23/24 (20130101) C12M 23/34 (20130101) C12M 23/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/14 (20130101) C12N 1/145 (20210501) Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/77 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031330 | Watkins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ORB Technologies, LLC (Lexington, Kentucky) |
| ASSIGNEE(S) | ORB Technologies, LLC (Lexington, Kentucky) |
| INVENTOR(S) | Virginia Watkins (Lexington, Kentucky) |
| ABSTRACT | An apparatus for resisting a gravity load is disclosed. The apparatus has a first end member, a second end member, and a plurality of elongated structural members, each of the plurality of elongated structural members including a first end portion attached to the first end member and a second end portion attached to the second end member. The plurality of elongated structural members is oriented to resist compressive stresses or tensile stresses induced by the gravity load. The plurality of elongated structural members is formed from plants with a harvest cycle of four years or fewer. |
| FILED | Monday, April 17, 2023 |
| APPL NO | 18/301352 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Structural Elements; Building Materials E04C 2/16 (20130101) Original (OR) Class E04C 2/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 12033519 | Larson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARCTOS Technology Solutions, LLC (Beavercreek, Ohio) |
| ASSIGNEE(S) | ARCTOS Technology Solutions, LLC (Beavercreek, Ohio) |
| INVENTOR(S) | Erik William Feldmeth Larson (Torrance, California); Tyler Gras (Torrance, California); Steven Carbon (Torrance, California) |
| ABSTRACT | Described are techniques for determining measures of risk through a medium fidelity, fast running flight risk analysis system, for evaluating risk of a launch or reentry. The method may include receiving trajectory information associated with a planned flight, wherein the trajectory information comprises a series of trajectory vectors, each trajectory vector comprising time information, position information and velocity information. Identification of consequences of interest, and an extent of a region of interest for potential hazard areas may also be received. The method may include determining an upper bound of expected consequence for each population center based on a number of people in each population center subject to different consequences, determining one or more collective risk metrics for each population center, and a collective risk metric for all population centers. |
| FILED | Wednesday, April 07, 2021 |
| APPL NO | 17/224445 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/242 (20130101) Traffic Control Systems G08G 5/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 12029686 | Mbagwu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The United States of America as represented by The Department Of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Michael Mbagwu (Mountain View, California); David Buickians (Glendale, California); David Myung (Saratoga, California) |
| ABSTRACT | Precise concentric, symmetric, and repeatable circular scoring (cutting) of Descemet's membrane is made possible by a handheld surgical ophthalmic device. The precision of the cut is provided by a stabilizing point on a stabilizing arm as well the anchoring insertion point at the limbus. Stabilization through the insertion point and the stabilizing arm provides a two-point fixation thereby establishing a cutting plane. The cutting plane allows for precise depth of cut whereas the rotating blade's consistent radius allows for circularity of the cut. The stabilization arm fixates on tissue, and is then removed when the procedure is completed. Consistent torque and contact pressure of the cutting blade is provided through rotational control via the depression of a button on a handle thereby removing the need to “free-hand” the desemetorhexis. |
| FILED | Tuesday, March 15, 2022 |
| APPL NO | 17/695484 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0133 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 12034650 | Beecroft et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| INVENTOR(S) | Jonathan Paul Beecroft (Bristol, United Kingdom); Anthony M. Ford (Bristol, United Kingdom); Trevor Alan Jones (Bridgwater, United Kingdom); Andrew S. Kopser (Seattle, Washington); Joseph Orth (Longmont, Colorado); David Charles Hewson (Bristol, United Kingdom); Abdulla M. Bataineh (Vista, California) |
| ABSTRACT | The efficient storage of transformation information in a switch is provided. A respective port of the switch can include a memory device capable of storing transformation information. During operation, the switch can apply a selection mechanism to the transformation information learned at the switch for identifying a target port. The switch can then store the information in the memory device of the target port. Upon receiving a packet, the ingress port can apply the selection mechanism to the header information of the packet for determining a location of a first piece of transformation information associated with the packet. The ingress port can obtain the first piece of transformation information by looking up the header information in the location and storing it in a local memory device. The ingress port can then transform the packet based on the first piece of transformation information for determining an egress port for the packet. |
| FILED | Tuesday, January 31, 2023 |
| APPL NO | 18/103943 |
| ART UNIT | 2441 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 49/252 (20130101) H04L 49/3027 (20130101) Original (OR) Class H04L 61/2592 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 12034582 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peraton Labs Inc. (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | Peraton Labs Inc. (Basking Ridge, New Jersey) |
| INVENTOR(S) | William Johnson (Basking Ridge, New Jersey); Kiran Rege (Basking Ridge, New Jersey); Achilles Kogiantis (Basking Ridge, New Jersey) |
| ABSTRACT | There is set forth herein, in one embodiment, receiving, by a transceiver of a UE device an aggregate signal stream, the aggregate signal stream including an aggregate of base station downlink signal streams from a plurality of base stations; processing the aggregate signal stream and detecting, from the processing of the aggregate signal stream, a set of base stations in communication range of the UE device, wherein the set of base stations include a current serving base station and a scanning base station; determining, from the processing of the aggregate signal stream, a Doppler shifted center frequency of a downlink scanning signal stream received from the scanning base station; and enhancing, in dependence on the Doppler shifted center frequency, the downlink scanning signal stream associated to the scanning base station. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/249590 |
| ART UNIT | 2413 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 7/088 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/2657 (20130101) Original (OR) Class Wireless Communication Networks H04W 48/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 12031434 | Adams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LUNAR RESOURCES, INC. (Houston, Texas) |
| ASSIGNEE(S) | Lunar Resources, Inc. (Houston, Texas) |
| INVENTOR(S) | Robert B. Adams (Huntsville, Alabama); Peter A. Curreri (Huntsville, Alabama) |
| ABSTRACT | A system and method for space resource mining and maneuvering may utilize at least one linear transformer driver, a selective ionization plasma pyrolysis extractor, and at least one pulsed plasma thruster. |
| FILED | Wednesday, February 02, 2022 |
| APPL NO | 17/591052 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/105 (20130101) B64G 1/405 (20130101) B64G 1/1071 (20230801) Mining or Quarrying E21C 51/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12031442 | Krumanaker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Matthew Lee Krumanaker (Blue Ash, Ohio); Thomas Joseph Lipinski (Monroe, Ohio) |
| ABSTRACT | A turbine engine comprising an engine core, a plurality of circumferentially arranged vanes, and a floating seal. The plurality of circumferentially arranged vanes forming an upper band and a lower band. The floating seal being carried by at least one respective vane of the plurality of circumferentially arranged vanes. The floating seal having a ring and at least one dynamic seal. |
| FILED | Thursday, December 01, 2022 |
| APPL NO | 18/072921 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/025 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 09, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240709.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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