FedInvent™ Patents
Patent Details for Tuesday, July 16, 2024
This page was updated on Wednesday, July 17, 2024 at 05:01 AM GMT
Department of Health and Human Services (HHS)
| US 12035720 | Roeder et al. |
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| FUNDED BY |
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| APPLICANT(S) | Jeffrey F. Roeder (Brookfield, Connecticut); Melissa A. Petruska (Newtown, Connecticut); Trevor E. James (Plantsville, Connecticut); Thomas J. Spoonmore (Norwalk, Connecticut); Peter C. Van Buskirk (Newtown, Connecticut) |
| ASSIGNEE(S) | Sonata Scientific LLC (Danbury, Connecticut) |
| INVENTOR(S) | Jeffrey F. Roeder (Brookfield, Connecticut); Melissa A. Petruska (Newtown, Connecticut); Trevor E. James (Plantsville, Connecticut); Thomas J. Spoonmore (Norwalk, Connecticut); Peter C. Van Buskirk (Newtown, Connecticut) |
| ABSTRACT | Polymer coatings and surfaces are disclosed with antimicrobial properties. The antimicrobial action is provided by high surface area materials contained within the coating or surface. The high surface area materials may contain photocatalysts that create reactive oxygen species upon exposure to visible light or transition metals that create reactive oxygen species upon exposure to hydrogen peroxide. The high surface area materials may also sorb disinfecting liquids and desorb them over time to provide disinfection. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/343723 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/10 (20130101) A01N 59/06 (20130101) A01N 59/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12035893 | Georgakoudi et al. |
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| APPLICANT(S) | Trustees of Tufts College (Boston, Massachusetts); Lahey Clinic, Inc. (Burlington, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Boston, Massachusetts); Lahey Clinic, Inc. (Burlington, Massachusetts) |
| INVENTOR(S) | Irene Georgakoudi (Acton, Massachusetts); Martin Hunter (Bradford, Massachusetts); Robert Michael Trout (Medford, Massachusetts); Thomas Schnelldorfer (Arlington, Massachusetts) |
| ABSTRACT | Methods and apparatus for improved imaging of internal tissue structures, such as lesions in the peritoneum, are disclosed employing Differentially Polarized Light (DPL) imaging. The optical system can include a laparoscope having at least one optical illumination waveguide for directing illuminating radiation and an optical collection waveguide having an aperture for collecting and transmitting radiation backscattered from a tissue region to a detector. The system further can include a polarizer for polarizing the illuminating radiation and a second analyzing polarizer disposed in the optical return path, whereby backscattered radiation of differing polarizations can be passed to the detector. End cap assemblies are also disclosed that that can be fitted to conventional laparoscopes, e.g., by a threaded connection or the like, to facilitate DPL imaging by polarizing the illuminating light of the laparoscope. For example, the end cap can include a polarizing film within a stainless steel housing. The polarizing film can be shaped to cover of the illumination outputs of the laparoscope, while leaving clear the aperture for collection of reflected or scattered radiation. |
| FILED | Friday, October 11, 2019 |
| APPL NO | 17/284413 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/07 (20130101) A61B 1/042 (20130101) A61B 1/00096 (20130101) A61B 1/00128 (20130101) A61B 1/00137 (20130101) A61B 1/0638 (20130101) A61B 1/0646 (20130101) Original (OR) Class A61B 1/0669 (20130101) A61B 1/3132 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12035971 | Abramoff et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of lowa Research Foundation (Iowa City, Iowa); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Michael D. Abramoff (University Heights, Iowa); Meindert Niemeijer (Iowa City, Iowa); Xiayu Xu (Iowa City, Iowa); Milan Sonka (Coralville, Iowa); Joseph M. Reinhardt (Iowa City, Iowa) |
| ABSTRACT | The methods and systems provided can automatically determine an Arteriolar-to-Venular diameter Ratio, AVR, in blood vessels, such as retinal blood vessels and other blood vessels in vertebrates. The AVR is an important predictor of increases in the risk for stroke, cerebral atrophy, cognitive decline, and myocardial infarct. |
| FILED | Friday, March 17, 2023 |
| APPL NO | 18/185704 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) Original (OR) Class A61B 3/0016 (20130101) A61B 3/0058 (20130101) A61B 3/1225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036073 | Hoerig et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Cameron Lee Hoerig (Champaign, Illinois); Michael F Insana (Urbana, Illinois); Jamshid Ghaboussi (Urbana, Illinois) |
| ABSTRACT | Systems and methods are provided for employing informational models trained using the Autoprogressive Algorithm to learn the mechanical behavior and internal structure of biological materials using a sparse sampling of force and displacement measurements. Forces are applied to the biological material and the force and displacement are measured and applied to the AutoP algorithm. Additionally, a coordinate based scaling factor is applied to the measured displacement. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 16/812023 |
| ART UNIT | 3798 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1121 (20130101) A61B 5/7264 (20130101) A61B 5/7267 (20130101) A61B 8/485 (20130101) Original (OR) Class A61B 8/5207 (20130101) A61B 8/5215 (20130101) Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036198 | Snodgrass et al. |
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| APPLICANT(S) | VISTAGEN THERAPUETICS, INC. (South San Francisco, California) |
| ASSIGNEE(S) | VISTAGEN THERAPUETICS, INC. (South San Francisco, California) |
| INVENTOR(S) | H. Ralph Snodgrass (South San Francisco, California); Allen E. Cato (Durham, North Carolina); Jack S. Hicklin (San Diego, California) |
| ABSTRACT | Compositions of L-4-chlorokynurenine are provided, as are methods for the treatment of neurological dysfunction. |
| FILED | Tuesday, June 21, 2022 |
| APPL NO | 17/845105 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/198 (20130101) Original (OR) Class A61K 31/198 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036212 | Kolesnick et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan-Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Richard Kolesnick (New York, New York); Adriana Haimovitz-Friedman (New York, New York); Evis Sala (New York, New York); Zvi Fuks (New York, New York) |
| ABSTRACT | Disclosed is a method for enhancing tumor response to chemotherapy, the method comprising administering a short-acting anti-angiogenic agent (AAA) capable of activating ASMase to a subject afflicted with a solid tumor, and thereby creating a time interval of increased susceptibility of said tumor to one or more chemotherapeutic agents, followed by administration of at least one chemotherapeutic agent within the interval. The interval can be defined in terms of a short-duration activation of ASMase signaling by the AAA. Disclosed are also methods for predicting the tumor response in a patient afflicted with a solid tumor to a chemotherapeutic agent, using as an indicator of the response ASMase level or activity (or ceramide level) in the patient following the administration of the chemotherapeutic agent to the patient, or dynamic IVIM based DW-MRI to measure perfusion alterations following administration of the chemotherapeutic agent. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/705798 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/404 (20130101) A61K 31/404 (20130101) A61K 31/4439 (20130101) Original (OR) Class A61K 31/4439 (20130101) A61K 31/7048 (20130101) A61K 31/7048 (20130101) A61K 31/7068 (20130101) A61K 31/7068 (20130101) A61K 33/24 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57488 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036222 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Wistar Institut of Anatomy and Biology (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Wistar Institut of Anatomy and Biology (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Rugang Zhang (Elskins Park, Pennsylvania); Sergey Karakashev (Philadelphia, Pennsylvania) |
| ABSTRACT | Therapeutic treatments for a disease such as a cancer are disclosed, including pharmaceutical compositions and methods of using pharmaceutical compositions for treating the cancer wherein the cancer cells overexpress arginine methyltransferase CARM1. In some embodiments, the therapeutic treatments disclosed include methods comprising the step of administering a therapeutically effective dose of an enhancer of zeste homolog 2 (EZH2) inhibitor to a subject, including a human subject, wherein the cancer cells of the subject overexpress arginine methyltransferase CARM1 and a PARP inhibitor. In some embodiments, the EZH2 inhibitors are administered in conjunction with platinum-based antineoplastic drugs. |
| FILED | Wednesday, April 03, 2019 |
| APPL NO | 17/045343 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/437 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/502 (20130101) A61K 31/4439 (20130101) A61K 31/4545 (20130101) A61K 31/5377 (20130101) A61K 31/7068 (20130101) A61K 31/7076 (20130101) A61K 35/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036223 | Allen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| INVENTOR(S) | Joshua E. Allen (Cambridge, Massachusetts); Gen Sheng Wu (Troy, Michigan); Wafik S. El-Deiry (Bryn Mawr, Pennsylvania) |
| ABSTRACT | Methods and compositions relating to TIC10 are described according to aspects of the present invention. The compositions and methods have utility in treating disease, particularly cancer in a subject in need thereof, including a human subject as well as subjects of other species. The compositions have utility in treating brain cancer in a subject in need thereof. |
| FILED | Monday, March 21, 2022 |
| APPL NO | 17/655646 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/513 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/4188 (20130101) A61K 31/4545 (20130101) A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/22 (20130101) C07K 2317/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6863 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036234 | Ameer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Guillermo A. Ameer (Chicago, Illinois); Jason A. Wertheim (Chicago, Illinois); Bin Jiang (Evanston, Illinois); Kyle Koss (Evanston, Illinois) |
| ABSTRACT | Disclosed are heparin conjugates comprising heparin conjugated to a peptide that binds to a protein of the extracellular matrix (ECM) of cellular tissue, such as a collagen-binding peptide that binds to collagen of the ECM. The disclosed heparin conjugates may be utilized in methods that include treating ECM material to incorporate the heparin conjugates and impart anticoagulant activity to the ECM. The disclosed heparin conjugates also may be formulated as pharmaceutical compositions for treating and/or preventing vascular injuries and conditions. |
| FILED | Thursday, October 11, 2018 |
| APPL NO | 16/755494 |
| ART UNIT | RD00 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/727 (20130101) Original (OR) Class A61K 38/08 (20130101) A61K 47/547 (20170801) A61K 47/6425 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036240 | Regev et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Ana Carrizosa Anderson (Boston, Massachusetts); Ayshwarya Subramanian (Cambridge, Massachusetts); Orit Rozenblatt-Rosen (Cambridge, Massachusetts) |
| ABSTRACT | This invention relates generally to compositions and methods for modulating complement component 3 (C3) activity or expression to treat, control or otherwise influence tumors and tissues, including cells and cell types of the tumors and tissues, and malignant, microenvironmental, or immunologic states of the tumor cells and tissues. The invention also relates to methods of diagnosing, prognosing and/or staging of tumors, tissues and cells. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/442348 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Peptides C07K 14/7051 (20130101) C07K 14/70596 (20130101) C07K 16/2818 (20130101) C07K 16/2827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036262 | Zhang |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Huang-Ge Zhang (Louisville, Kentucky) |
| ABSTRACT | Provided are methods for modulating gut microbiota in subjects. In some embodiments, the methods include administering to a subject an effective amount of a composition that includes a first edible plant-derived nanoparticle encapsulating an effective amount of RNA. Also provided are methods for preventing and/or treating gut dysbiosis, methods for modulating bacterial growth, methods for modulating inflammatory cytokines, methods for reducing migration of bacterial from the gut to gut-associated bloodstream, and compositions for use in the presently disclosed methods, including pharmaceutical compositions. |
| FILED | Wednesday, November 21, 2018 |
| APPL NO | 16/766055 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/148 (20130101) A61K 9/1271 (20130101) A61K 9/5176 (20130101) A61K 36/9068 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/141 (20130101) C12N 2330/10 (20130101) C12N 2501/2322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036264 | Cadete Pires et al. |
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| APPLICANT(S) | NovoBiotic Pharmaceuticals, LLC (Cambridge, Massachusetts) |
| ASSIGNEE(S) | NovoBiotic Pharmaceuticals, LLC (Cambridge, Massachusetts) |
| INVENTOR(S) | Ana Cristina Cadete Pires (Cambridge, Massachusetts); Aranda Rae Duan (Medford, Massachusetts); Losee Lucy Ling (Arlington, Massachusetts) |
| ABSTRACT | The present invention provides pharmaceutical compositions of teixobactin that are capable of preventing gelation of teixobactin. The pharmaceutical compositions comprise teixobactin and a pegylated phospholipid. The present invention also provides methods of preparing the pharmaceutical compositions of teixobactin and methods of treating a subject using the pharmaceutical compositions of teixobactin. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/969598 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/15 (20130101) Original (OR) Class A61K 47/24 (20130101) A61K 47/26 (20130101) A61K 47/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036265 | Kim |
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| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Hyeong-Reh C. Kim (Bloomfield, Michigan) |
| ABSTRACT | Methods of treating a subject in need thereof are provided which include: administering a recombinant platelet derived growth factor D (PDGF D) composition to a mesenchymal stem cell of the subject and/or a progenitor derived therefrom, in vivo, or ex vivo, producing a treated mesenchymal stem cell of the subject and/or a progenitor derived therefrom, thereby stimulating the mesenchymal stem cell (MSC) and/or a progenitor derived therefrom. Cells expressing a recombinant PDGF D composition of the present are administered to the subject for in vivo delivery of the recombinant PDGF D composition according to aspects of the present disclosure. Methods and compositions are provided including recombinant PDGF D hemidimer (HD) including a full-length PDGF D polypeptide and a C-terminal growth factor domain of PDGF D, which lacks a CUB domain, promoting regulation of bone marrow MSC differentiation into osteogenic lineage cells. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 17/362008 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 38/1858 (20130101) Original (OR) Class A61K 47/642 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/08 (20180101) Peptides C07K 14/49 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036269 | Georgiou et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | George Georgiou (Austin, Texas); Everett Stone (Austin, Texas); Wei-Cheng Lu (Austin, Texas) |
| ABSTRACT | Methods and compositions relating to the engineering of an improved protein with homocyst(e)inase enzyme activity are described. For example, there are disclosed modified cystathionine-γ-lyase (CGL) enzymes comprising one or more amino acid substitutions and capable of degrading homocyst(e)ine. Furthermore, provided are compositions and methods for the treatment of homocystinuria or hyperhomocysteinemia with homocyst(e)ine depletion using the disclosed enzymes or nucleic acids. |
| FILED | Tuesday, May 25, 2021 |
| APPL NO | 17/330106 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 31/198 (20130101) A61K 31/4415 (20130101) A61K 38/51 (20130101) Original (OR) Class A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 9/96 (20130101) C12N 15/70 (20130101) C12N 15/80 (20130101) C12N 15/861 (20130101) C12N 15/867 (20130101) C12N 15/869 (20130101) Enzymes C12Y 404/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036279 | Deng et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Liang Deng (New York, New York); Stewart Shuman (New York, New York); Jedd Wolchok (New York, New York); Taha Merghoub (New York, New York); Weiyi Wang (New York, New York); Peihong Dai (New York, New York); Ning Yang (New York, New York) |
| ABSTRACT | The present disclosure relates generally to the fields of oncology, virology and immunotherapy. It concerns poxviruses, specifically the highly attenuated modified vaccinia virus Ankara (MVA), and a recombinant modified vaccinia Ankara virus with deletion of vaccinia virulence factor E3 (MVAΔE3L), each further modified to express human Fms-like tyrosine kinase 3 ligand (Flt3L) or GM-CSF. The disclosure relates to use of the foregoing recombinant viruses as cancer immunotherapeutic agents. The foregoing recombinant poxviruses can also be used in combination with immune checkpoint blockade therapy. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 17/681342 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/768 (20130101) A61K 39/0011 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 39/3955 (20130101) A61K 2039/505 (20130101) A61K 2039/55522 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/521 (20130101) C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2710/24032 (20130101) C12N 2710/24121 (20130101) C12N 2710/24132 (20130101) C12N 2710/24143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036314 | Myung et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The U.S. Government Represented by the Department of Veterans Affairs (NW Washington, District of Columbia) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | David Myung (Stanford, California); Sarah Hull (Stanford, California); Sarah Heilshorn (Mountain View, California); Christopher Lindsay (San Mateo, California); Christopher Madl (Los Altos, California); Hyun Jong Lee (Gyeonggi-do, South Korea) |
| ABSTRACT | Compositions and methods are provided for lamellar and defect reconstruction of corneal stromal tissue using biomaterials that form a defined gel structure in situ. Such gels can serve as cellular or acellular lamellar substitutes to reconstruct corneal stroma, facilitate matrix remodeling, and support multilayered re-epithelialization of wounded corneal stromal tissue, as well delivery vehicles for cells, biomolecules, and/or pharmaceutical agents to wound sites throughout the body. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 17/251605 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/142 (20130101) A61F 2210/0076 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0051 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/36 (20130101) A61K 47/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036319 | Gao et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Jinming Gao (Dallas, Texas); Suxin Li (Dallas, Texas) |
| ABSTRACT | Described herein are therapeutic pH responsive compositions useful for the treatment of cancer. The compositions involve combining a STING activating polymer micelle, such as PC7A, with a non-peptide STING agonist, such as cGAMP. Methods of administering these compositions in the treatment of cancer are also disclosed. These methods include administration of the pharmaceutical compositions by intratumoral injection in the treatment of solid tumors. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/469111 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/5377 (20130101) A61K 31/7076 (20130101) A61K 47/32 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036339 | Martin et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Russell Martin (Baltimore, Maryland); Hai-Quan Mao (Baltimore, Maryland); Sashank Reddy (Baltimore, Maryland); Kevin Colbert (Baltimore, Maryland) |
| ABSTRACT | A composite material can include a gel and at least one nanostructure disposed within the gel. A method for healing a soft tissue defect can include applying a composite material to a soft tissue defect, wherein the composite material includes a gel and a nanostructure disposed within the gel. A method for manufacturing a composite material for use in healing soft tissue defects can include providing a gel and disposing nanofibers within the gel. |
| FILED | Thursday, July 18, 2019 |
| APPL NO | 16/515819 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) Original (OR) Class A61L 27/3633 (20130101) A61L 2300/62 (20130101) A61L 2300/236 (20130101) A61L 2400/06 (20130101) A61L 2430/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036384 | Leira et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | University of lowa Research Foundation (lowa City, Iowa) |
| INVENTOR(S) | Enrique C. Leira (Iowa City, Iowa); Thomas Schnell (Iowa City, Iowa); Salam F. Rahmatalla (Iowa City, Iowa); Andrew A. Pieper (Iowa City, Iowa); Anil Chauhan (Iowa City, Iowa) |
| ABSTRACT | The disclosed apparatus, systems and methods relate to devices, systems and methods for improving thrombolysis via synergetic application of thrombolytics with physical factors, such as in acute ischemic stroke patients. Vibration in the low (0.5-120 Hz) frequency range is synergistic with tissue plasminogen activators (rtPA), significantly improving the effectiveness of thrombolysis without impairing blood brain barrier permeability. Administration of low frequency vibration combined with rtPA improve acute ischemic stroke outcomes. |
| FILED | Wednesday, February 05, 2020 |
| APPL NO | 16/783003 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/001 (20130101) A61H 2201/5048 (20130101) A61H 2209/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) Original (OR) Class A61M 2005/14208 (20130101) A61M 2202/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036421 | Bruza et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Petr Bruza (Lebanon, New Hampshire); Brian Pogue (Hanover, New Hampshire); Ramish Ashraf (Hanover, New Hampshire); Rongxiao Zhang (Hanover, New Hampshire); David Gladstone (Norwich, Vermont); Megan Clark (Hanover, New Hampshire); Roman Vasyltsiv (Staten Island, New York) |
| ABSTRACT | A system for delivering ultra-high dose rate irradiation to a target area of a patient, includes a pulsed charged-particle source along a beam axis; a collimator for shaping the beam of radiation; one or more cameras for imaging the target area of the patient; and a dosimetry controller for providing control signals to the charged-particle source one or more dosimeters positioned between an output of the charged-particle source and the collimator in beam fringes for measuring a radiation dosage provided by each pulse; and a beam scanning coil positioned between the collimator and the patient for directing the shaped beam. The dosimetry controller receives feedback from the one or more dosimeters and provides control signals to the particle source and the beam scanning coil that modulate final pulses in the series of pulses in real-time. |
| FILED | Wednesday, May 25, 2022 |
| APPL NO | 18/563813 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1031 (20130101) Original (OR) Class A61N 5/1049 (20130101) A61N 5/1067 (20130101) A61N 5/1071 (20130101) A61N 2005/1059 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037257 | Noh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | POSTECH Research and Business Development Foundation (Pohang-si, South Korea) |
| ASSIGNEE(S) | POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION (Pohang-si, South Korea) |
| INVENTOR(S) | Yongyoung Noh (Daejeon, South Korea); Youngki Kim (Pohang-si, South Korea); Jisu Hong (Pohang-si, South Korea) |
| ABSTRACT | A method of producing perovskite nanocrystalline particles using a liquid crystal includes a first operation for preparing a mixed solution including a first precursor compound, a second precursor compound, and a first solvent. a second operation for preparing a precursor solution by adding an organic ligand to the prepared mixed solution, a third operation for performing crystallization treatment after adding the prepared precursor solution to a reactor containing a liquid crystal, and a fourth operation for separating the perovskite nanocrystalline particles from the crystallized solution through a centrifugal separator. |
| FILED | Wednesday, December 09, 2020 |
| APPL NO | 17/420769 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 19/006 (20130101) Original (OR) Class C01G 21/006 (20130101) C01G 29/006 (20130101) C01G 30/002 (20130101) C01G 45/006 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/57 (20130101) C09K 11/664 (20130101) C09K 11/665 (20130101) C09K 11/755 (20130101) C09K 11/756 (20130101) C09K 11/7428 (20130101) C09K 11/7435 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037317 | Ulrich |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Buck Institute for Research on Aging (Novato, California) |
| ASSIGNEE(S) | Buck Institute for Research on Aging (Novato, California) |
| INVENTOR(S) | Scott Michael Ulrich (Brooktondale, New York) |
| ABSTRACT | In various embodiments methods of preparing hydroxybutyryl 3-hydroxybutyrate and related compounds are provided along with methods of use thereof. |
| FILED | Friday, January 18, 2019 |
| APPL NO | 15/733403 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) Acyclic or Carbocyclic Compounds C07C 69/675 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/20 (20130101) C12N 11/06 (20130101) C12N 11/087 (20200101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) C12P 7/52 (20130101) C12P 7/62 (20130101) C12P 41/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037329 | Tu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Zhude Tu (St. Louis, Missouri); Vijai Kumar Reddy Tangadanchu (St. Louis, Missouri); Hao Jiang (St. Louis, Missouri); Buck Rogers (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of SphK inhibitors and methods of making and using same. An aspect of the present disclosure provides for an SphK2 inhibiting agent, wherein the SphK2 inhibiting agent is a 1,2,3-triazole having SphK2 inhibiting activity and SphK2 selectivity. |
| FILED | Tuesday, August 16, 2022 |
| APPL NO | 17/820137 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 413/10 (20130101) C07D 413/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037355 | Gin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADJUVANCE TECHNOLOGIES, INC. (Lincoln, Nebraska); MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | ADJUVANCE TECHNOLOGIES, INC. (Lincoln, Nebraska); MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | David Y. Gin (Lincoln, Nebraska); Eric Chea (Oakland, California); Alberto Fernandez-Tejada (Logroño. La Rioja, Spain); Jeffrey Gardner (New York, New York); Jason Lewis (New York, New York); Philip Livingston (New York, New York); J. Tyler Martin (Roca, Nebraska); Lars Nordstroem (New York, New York); Naga Vara Kishore Pillarsetty (Jackson Heights, New York); Govind Ragupathi (New York, New York); Derek Tan (New York, New York) |
| ABSTRACT | The present application relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, and intermediates thereto. The application also provides pharmaceutical compositions comprising compounds of the present invention and methods of using said compounds or compositions in the treatment of and immunization for infectious diseases. |
| FILED | Wednesday, March 08, 2023 |
| APPL NO | 18/180421 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7024 (20130101) A61K 39/08 (20130101) A61K 39/39 (20130101) A61K 39/099 (20130101) A61K 2039/10 (20130101) A61K 2039/55583 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) Original (OR) Class C07H 13/04 (20130101) C07H 13/06 (20130101) C07H 13/08 (20130101) Steroids C07J 63/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037386 | Kurtis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rhode Island Hospital (Providence, Rhode Island) |
| ASSIGNEE(S) | RHODE ISLAND HOSPITAL (Providence, Rhode Island) |
| INVENTOR(S) | Jonathan Kurtis (Providence, Rhode Island); Dipak K. Raj (Providence, Rhode Island); Alok Das Mohapatra (Providence, Rhode Island); Jenna Zuromski (Providence, Rhode Island) |
| ABSTRACT | Provided herein are methods, compositions and kits for preventing and treating malaria. Also included herein are kits for preventing and treating malaria. |
| FILED | Wednesday, May 10, 2023 |
| APPL NO | 18/315456 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) Peptides C07K 16/205 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037402 | Weissman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Irving L. Weissman (Stanford, California); Stephen Willingham (Mountain View, California); Doris Po Yi Ho (Daly City, California); Piero D. Dalerba (New York, New York); Kelly Marie McKenna (Palo Alto, California); Jens-Peter Volkmer (Menlo Park, California) |
| ABSTRACT | Methods are provided for targeting cells for depletion, including, without limitation, cancer cells, in a regimen comprising contacting the targeted cells with a combination of agents, including (i) an agent that blockades CD47 activity; and (ii) an antibody that specifically binds to EGFR. In some embodiments the cancer cells have a mutated form of one or more of KRAS, NRAS and BRAF. The level of depletion of the targeted cell is enhanced relative to a regimen in which a single agent is used; and the effect may be synergistic relative to a regimen in which a single agent is used. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 17/411953 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 2039/507 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2803 (20130101) C07K 16/2839 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037403 | Orentas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lentigen Technology, Inc. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | LENTIGEN TECHNOLOGY, INC. (Gaithersburg, Maryland); The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Rimas J. Orentas (Seattle, Washington); Dina Schneider (Potomac, Maryland); Boro Dropulic (Ellicott City, Maryland); Dimiter S. Dimitrov (Frederick, Maryland); Zhongyu Zhu (Frederick, Maryland) |
| ABSTRACT | Chimeric antigen receptors containing CD123 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed. |
| FILED | Thursday, November 12, 2020 |
| APPL NO | 17/095982 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) C07K 16/2866 (20130101) Original (OR) Class C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/1037 (20130101) C12N 2740/15041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037404 | Ip et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Hong Kong University of Science and Technology (Hong Kong, China PRC); THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (Hong Kong, China PRC) |
| INVENTOR(S) | Nancy Yuk-Yu Ip (Hong Kong, China PRC); Kit Yu Fu (Hong Kong, China PRC); Wing Yu Fu (Hong Kong, China PRC); Dimiter S. Dimitrov (Frederick, Maryland); Tianlei Ying (Frederick, Maryland) |
| ABSTRACT | The present invention provides new, fully human EphA4 monoclonal antibodies with distinct binding characteristics. Also disclosed are antigen binding fragments of these antibodies, bispecific forms of these antibodies, and conjugates of these antibodies. In addition, nucleic acids encoding these antibodies, antigen binding fragments, bispecific antibodies and conjugates are disclosed. These monoclonal antibodies, antigen binding fragments, bispecific antibodies, conjugates, nucleic acids and vector are of use for identifying and treating a subject with a disease or condition involving abnormal EphA4-mediated signaling. |
| FILED | Monday, February 15, 2021 |
| APPL NO | 17/175879 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 35/00 (20180101) Peptides C07K 14/71 (20130101) C07K 16/2866 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 33/57492 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037419 | Diamond |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| ASSIGNEE(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| INVENTOR(S) | Betty A. Diamond (Bronx, New York) |
| ABSTRACT | Fusion proteins of C1q peptides and HMBG1 A-box or HMBG1 B-box, or C1q peptides and DWESY peptide are provided, and methods of use thereof. |
| FILED | Tuesday, October 12, 2021 |
| APPL NO | 17/499043 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 14/472 (20130101) C07K 14/4702 (20130101) C07K 16/46 (20130101) C07K 16/2803 (20130101) C07K 2317/31 (20130101) C07K 2317/72 (20130101) C07K 2317/94 (20130101) C07K 2317/732 (20130101) C07K 2319/00 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037529 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, the State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Ki-Bum Lee (Piscataway, New Jersey); Hudifah Rabie (Piscataway, New Jersey); Nicholas Pasquale (Piscataway, New Jersey); Yixiao Zhang (Piscataway, New Jersey) |
| ABSTRACT | Disclosed herein are embodiments of a composition comprising at least three layers. Layers one and two each either comprises a sensitizer or an emitter, typically a metal ion or a dye, and the third layer may or may not comprise a sensitizer or emitter. Upon exposure to light, such as infrared light, the composition produces visible and/or UV light. The composition may further comprise a capping moiety, a therapeutic agent, an uptake enhancer, a detection moiety that binds to a desired target, a quenching moiety, or a combination thereof. The composition may be a particle, such as a nanoparticle, or it may be a planar composition. Also disclosed are embodiments of a method for using the composition, including, but not limited to, a method for delivering a therapeutic agent, or a method for detecting a target, such as a biological target. |
| FILED | Wednesday, December 30, 2020 |
| APPL NO | 17/137813 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/203 (20130101) A61K 49/0013 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/0833 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2500/05 (20130101) C12N 2506/03 (20130101) C12N 2529/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037597 | Rao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Catholic University of America (Washington, District of Columbia) |
| ASSIGNEE(S) | The Catholic University of America (Washington, District of Columbia) |
| INVENTOR(S) | Venigalla B. Rao (Silver Spring, Maryland); Jingen Zhu (Washington, District of Columbia) |
| ABSTRACT | Described is hybrid viral vector comprising: a first virus such as bacteriophage T4; one or more second virus such as adeno-associated virus (AAV) attached to the first virus through cross-bridges, such as avidin-biotin cross-bridges; one or more DNA molecules packaged in the first virus; one or more nucleic acid molecules packaged in the second virus; and one or more proteins displayed on the surface of the first virus. Also described are methods of making and using such a hybrid viral vector. |
| FILED | Wednesday, September 29, 2021 |
| APPL NO | 17/488542 |
| ART UNIT | 1638 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14133 (20130101) C12N 2750/14134 (20130101) C12N 2795/10133 (20130101) C12N 2795/10134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037598 | Asokan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Aravind Asokan (Durham, North Carolina); Trevor Gonzalez (Durham, North Carolina); Lawrence Patrick Havlik (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides adeno-associated virus (AAV) vectors, comprising coevolved capsid variant proteins, pharmaceutical compositions, methods of making, and methods for delivering such to a subject. |
| FILED | Tuesday, September 26, 2023 |
| APPL NO | 18/474533 |
| ART UNIT | 1638 — Plants |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037606 | Hematti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Peiman Hematti (Middleton, Wisconsin); Debra Bloom (Sun Prairie, Wisconsin) |
| ABSTRACT | The present disclosure relates to methods, cells, and compositions for preparing T cell populations and compositions for adoptive cell therapy. In particular, provided herein are methods for efficiently expanding and activating T cell populations for genetic engineering and adoptive T cell immunotherapies. Also provided are cells and compositions produced by the methods and methods of their use. |
| FILED | Tuesday, January 07, 2020 |
| APPL NO | 16/736389 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/17 (20130101) A61K 2039/5158 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) Original (OR) Class C12N 2501/25 (20130101) C12N 2501/50 (20130101) C12N 2501/51 (20130101) C12N 2501/515 (20130101) C12N 2501/599 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037607 | Vizcardo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Raul E. Vizcardo (Foster City, California); Naritaka Tamaoki (North Bethesda, Maryland); Meghan L. Good (Derwood, Maryland); Nicholas P. Restifo (Chevy Chase, Maryland) |
| ABSTRACT | Disclosed are methods of preparing CD34+CD43+ hematopoietic progenitor cells (HPC) in vitro according to embodiments of the invention. Also disclosed are methods of differentiating CD34+CD43+ hematopoietic progenitor cells to hematopoietic lineage cells according to embodiments of the invention. Also disclosed are methods of treating or preventing a condition in a mammal, e.g., cancer, according to embodiments of the invention. |
| FILED | Thursday, November 08, 2018 |
| APPL NO | 16/762447 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) Original (OR) Class C12N 2500/98 (20130101) C12N 2501/20 (20130101) C12N 2501/22 (20130101) C12N 2501/24 (20130101) C12N 2501/25 (20130101) C12N 2501/115 (20130101) C12N 2501/125 (20130101) C12N 2501/135 (20130101) C12N 2501/145 (20130101) C12N 2501/155 (20130101) C12N 2501/165 (20130101) C12N 2501/415 (20130101) C12N 2501/2303 (20130101) C12N 2501/2306 (20130101) C12N 2502/00 (20130101) C12N 2506/45 (20130101) C12N 2513/00 (20130101) C12N 2531/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037619 | Landau et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | NEW YORK UNIVERSITY (New York, New York) |
| INVENTOR(S) | Nathaniel R. Landau (New York, New York); Takuya Tada (New York, New York) |
| ABSTRACT | Provided are polypeptides comprising an enzymatically inactive angiotensin-converting enzyme 2 (ACE2) ectodomain, a segment of an immunoglobulin Fc and optionally a purification tag. A cDNA or an expression vector encoding the polypeptide along with a method of culturing cells comprising the expression vector is also provided. The disclosure also provides a method for prophylaxis or therapy for a Coronavirus infection by administering the polypeptide to an individual in need thereof. |
| FILED | Wednesday, August 18, 2021 |
| APPL NO | 17/405104 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/4813 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 2319/21 (20130101) C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) Original (OR) Class Enzymes C12Y 304/17023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037639 | Abudayyeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Omar Abudayyeh (Cambridge, Massachusetts); James Joseph Collins (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Feng Zhang (Cambridge, Massachusetts); Eric S. Lander (Cambridge, Massachusetts) |
| ABSTRACT | The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA. |
| FILED | Monday, February 25, 2019 |
| APPL NO | 16/285128 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6811 (20130101) C12Q 1/6816 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037647 | Song et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Jin Song (Baltimore, Maryland); Zhen Zhang (Dayton, Maryland); Daniel Wan-yui Chan (Clarksville, Maryland) |
| ABSTRACT | Provided herein are methods of detecting pancreatic cancer in a subject, the method comprising measuring in a sample from the subject a level of CA19-9 polysaccharide relative to a reference, and a level of a polynucleotide or polypeptide of at least one marker selected from the group consisting of: OPN, MIA, CEACAM-1, MIC-1, SPON1, HSP27, POSTN, and LGALS3BP relative to a reference, wherein an increased level of the CA19-9 polysaccharide relative to a reference and an increased level of the polynucleotide or polypeptide relative to a reference indicates presence of pancreatic cancer in the subject. |
| FILED | Tuesday, September 08, 2020 |
| APPL NO | 17/013989 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/4748 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038377 | Min et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Wei Min (Edgewater, New Jersey); Lu Wei (Anhui, China PRC); Zhixing Chen (Beijing, China PRC); Fanghao Hu (New York, New York); Yihui Shen (Jiangsu, China PRC) |
| ABSTRACT | Exemplary methods, systems and computer-accessible medium for detecting at least one condition of at least one disease. In particular, it is possible to administer at least one composition to at least one patient, where the at least one composition includes at least one bond-edited compound configured to target at least one of a disease tissue or a pathogen. Further, it is possible to receive information related to the administration of the composition to the patient. It is also possible to detect the at least one bond-edited compound using a Raman scattering arrangement. |
| FILED | Wednesday, March 21, 2018 |
| APPL NO | 15/927463 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/00 (20130101) A61K 49/0013 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 21/4795 (20130101) Original (OR) Class G01N 33/58 (20130101) G01N 33/5005 (20130101) G01N 2021/655 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038382 | Yao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CLEMSON UNIVERSITY (Clemson, South Carolina) |
| ASSIGNEE(S) | CLEMSON UNIVERSITY RESEARCH FOUNDATION (Clemson, South Carolina) |
| INVENTOR(S) | Hai Yao (Clemson, South Carolina); Tong Ye (Clemson, South Carolina); Peng Chen (Clemson, South Carolina); Xun Chen (Clemson, South Carolina) |
| ABSTRACT | Herein are described data acquisition systems and methods applying such systems to determine three-dimensional (3D) diffusion tensors, and simultaneously, to perform 3D structure imaging. Example data acquisition systems can include computing systems in communication with modified light sheet microscopes that are configured for high-speed volumetric imaging to record 3D diffusion processes and high-resolution 3D structural imaging. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 17/378093 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) G01N 21/6486 (20130101) Original (OR) Class G01N 2201/0635 (20130101) Optical Elements, Systems, or Apparatus G02B 21/008 (20130101) G02B 21/0032 (20130101) G02B 21/0076 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038407 | Herr et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Amy E. Herr (Berkeley, California); Lin He (Berkeley, California); Andrew J. Modzelewski (Berkeley, California); Elisabet Rosàs-Canyelles (Berkeley, California) |
| ABSTRACT | Dual nucleic acid and protein isoform measurements are performed on low starting cell numbers (e.g. equivalent to the number of blastomeres composing early embryonic development stages (morula and blastocysts)), comprising integrating fractionation polyacrylamide gel electrophoresis (fPAGE) of 10-100 cells with off-chip analysis of nucleic acids in the nuclei. |
| FILED | Monday, May 24, 2021 |
| APPL NO | 17/327806 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/40 (20130101) C08J 2333/26 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/1545 (20130101) Compositions of Macromolecular Compounds C08L 33/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44747 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038430 | Verkman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alan S. Verkman (San Francisco, California); Byung-Ju Jin (San Francisco, California); Sujin Lee (San Francisco, California) |
| ABSTRACT | Provided herein are methods and systems for screening a candidate agent to determine whether the candidate agent modulates an activity of cultured cells. Compositions for screening a candidate agent are also provided herein. |
| FILED | Thursday, April 25, 2019 |
| APPL NO | 17/046099 |
| ART UNIT | 1675 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2200/027 (20130101) B01L 2300/0819 (20130101) B01L 2300/0861 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) Original (OR) Class G01N 2800/382 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038432 | Skardal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | WAKE FOREST UNIVERSITY HEALTH SCIENCES (Winston-Salem, North Carolina) |
| INVENTOR(S) | Aleksander Skardal (Dublin, Ohio); Konstantinos Votanopoulos (Winston-Salem, North Carolina) |
| ABSTRACT | Described herein are organoids that include at least one type of immune cell along with systems and devices including the same. Methods of preparing and using such organoids, devices and systems are also described herein. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/966406 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) C12N 5/0693 (20130101) C12N 5/0697 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5082 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038608 | Bandyopadhyay et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Saumil Bandyopadhyay (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | The next-generation of optoelectronic systems will require efficient optical signal transfer between many discrete photonic components integrated onto a single substrate. While modern assembly processes can easily integrate thousands of electrical components onto a single board, photonic assembly is far more challenging due to the wavelength-scale alignment tolerances required. Here we address this problem by introducing a self-aligning photonic coupler insensitive to x, y, z displacement and angular misalignment. The self-aligning coupler provides a translationally invariant evanescent interaction between waveguides by intersecting them at an angle, which enables a lateral and angular alignment tolerance fundamentally larger than non-evanescent approaches such as edge coupling. This technology can function as a universal photonic connector interfacing photonic integrated circuits and microchiplets across different platforms. For example, it can be used in a self-aligning photonic circuit board that can be assembled more easily, with larger misalignment tolerances, than other complex optoelectronic systems. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470803 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) Original (OR) Class G02B 2006/12147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038767 | Huang et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Jane Huang (South Bend, Indiana); Michael Vierhauser (South Bend, Indiana); Ankit Agrawal (South Bend, Indiana) |
| ABSTRACT | A method for configuring a multiple autonomous drone mission includes displaying, a plurality of queries on a display of the computing device. The method further includes receiving, via a user interface, a plurality of inputs responsive to the plurality of queries. At least a first input of the plurality of inputs specifies a type of mission to be performed and at least a second input of the plurality of inputs specifies a geographical area in which a mission to be performed will be carried out. The method further includes automatically determining, based on the plurality of inputs, an initial location to move to for each of a plurality of drones available for implementing the mission. The method further includes automatically determining, based on the plurality of inputs, a series of tasks for each of the plurality of drones. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 17/571449 |
| ART UNIT | 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Unmanned aerial vehicles [UAV]; equipment therefor B64U 2101/00 (20230101) B64U 2101/30 (20230101) Systems for Controlling or Regulating Non-electric Variables G05D 1/104 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/029 (20180201) H04W 4/30 (20180201) H04W 4/90 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039723 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Hongjie Dai (Cupertino, California); Zhuoran Ma (Stanford, California) |
| ABSTRACT | A method for enhancing a near-infrared fluorescence image includes providing a NIR fluorescence image produced by detecting light in the NIR-I or NIR-IIa windows emitted by fluorophores; and inputting the NIR fluorescence image to a convolutional neural network to produce as output a translated image, where the convolutional neural network is trained using a set of NIR-I or NIR-IIa fluorescence images and a set of NIR-IIb fluorescence images. Preferably, the convolutional neural network is a U-Net. |
| FILED | Saturday, September 11, 2021 |
| APPL NO | 17/472620 |
| ART UNIT | 2682 — Optics |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10048 (20130101) G06T 2207/10056 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039735 | Feng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Xue Feng (Lexington, Kentucky); Quan Chen (Lexington, Kentucky); Kanchan Ghimire (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xue Feng (Lexington, Kentucky); Quan Chen (Lexington, Kentucky); Kanchan Ghimire (Arlington, Virginia) |
| ABSTRACT | The present disclosure relates to a method and apparatus for automatic head and neck organ segmentation. The method includes: prepare a training dataset, wherein the step of preparing a training dataset comprises: receive 3D images covering head and neck region obtained by a CT system or an MRI system; receive metadata for each received 3D images, comprising patient orientation, pixel spacing, slice thickness and matrix size; receive corresponding 3D segmentation labels map for the received 3D images; and process the received 3D images and the corresponding 3D segmentation labels map by transforming to patient coordinate system and resampling to have a fixed spatial resolution and a fixed matrix size; build a deep learning framework using CNN models for organ segmentation; train CNN models using the training dataset and performing data emulation step during training by mirroring the processed 3D images and their corresponding processed 3D segmentation labels map from the training dataset; prepare a testing dataset, wherein the step of preparing a testing dataset comprises: receive 3D images covering head and neck region obtained by a CT system or an MRI system; receive metadata for each received 3D images, comprising patient orientation, pixel spacing, slice thickness and matrix size; and process the received 3D images by transforming to patient coordinate system and resampling to have a fixed spatial resolution and a fixed matrix size; deploy the trained CNN models on testing dataset, wherein the testing step comprises: mirror the processed 3D images in the left-right direction; predict on the processed 3D images and mirrored 3D images with individual prediction outputs as 3D probabilities map for organ segmentation; and improve the segmentation performance by averaging the 3D probabilities map outputs from the processed 3D images and mirrored 3D images; and post-process the 3D probabilities map outputs from the deep learning framework to obtain final 3D segmentation labels map for organ segmentation. |
| FILED | Wednesday, November 17, 2021 |
| APPL NO | 17/529188 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/168 (20170101) Original (OR) Class G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20216 (20130101) G06T 2207/30004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039738 | Siewerdsen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Jeffrey H. Siewerdsen (Baltimore, Maryland); Wojciech Zbijewski (Baltimore, Maryland); Alejandro Sisniega (Baltimore, Maryland); Joseph Webster Stayman (Baltimore, Maryland) |
| ABSTRACT | The present invention is directed to a method of multi-motion compensation for high-quality cone-beam CT of the head. A multi-stage approach is incorporated that includes a pre-conditioning stage in which an initial estimation of the motion trajectory is obtained with 3D-2D registration using the motion-contaminated CBCT and projection data. In the present invention, the motion-contaminated CBCT is used as a basis for 3D-2D registration in the pre-conditioning stage to capture large amplitude, rapid movements of the head and provide better initialization of the autofocus solution. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 17/056639 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/501 (20130101) A61B 6/4021 (20130101) A61B 6/4085 (20130101) A61B 6/5205 (20130101) A61B 6/5264 (20130101) Image Data Processing or Generation, in General G06T 7/20 (20130101) Original (OR) Class G06T 2207/10081 (20130101) G06T 2207/20201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039765 | Buckler et al. |
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| FUNDED BY |
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| APPLICANT(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| INVENTOR(S) | Andrew J. Buckler (Boston, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts); Mark A. Buckler (Wenham, Massachusetts); Vladimir Valtchinov (Boston, Massachusetts); David S. Paik (Moon Bay, California) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Monday, May 01, 2023 |
| APPL NO | 18/309903 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/24 (20230101) G06F 18/211 (20230101) G06F 18/2148 (20230101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 3/00 (20130101) G06T 5/73 (20240101) G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 2207/10048 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10101 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/30096 (20130101) G06T 2207/30104 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) Original (OR) Class G06V 10/764 (20220101) G06V 20/69 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040050 | Khimulya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Grigory Khimulya (Cambridge, Massachusetts); Ethan Alley (Albuquerque, New Mexico); Surojit Biswas (Boston, Massachusetts) |
| ASSIGNEE(S) | NABLA BIO, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | Grigory Khimulya (Cambridge, Massachusetts); Ethan Alley (Albuquerque, New Mexico); Surojit Biswas (Boston, Massachusetts) |
| ABSTRACT | A dataset describing a collection of proteins is loaded, which identifies, for each protein, a respective value of a characteristic of interest. The dataset is provided as one or more inputs to a trained unsupervised representation model to cause the trained unsupervised representation model to generate a representation for each protein in the collection. The representation for each protein is input into a supervised top model to train the supervised top model to obtain a predicted characteristic and the trained supervised top model is used to obtain a predicted characteristic for a particular protein. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 16/812111 |
| ART UNIT | RD00 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) G06N 3/084 (20130101) G06N 3/088 (20130101) G06N 3/0442 (20230101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 15/00 (20190201) G16B 20/00 (20190201) G16B 25/10 (20190201) G16B 30/00 (20190201) Original (OR) Class G16B 35/00 (20190201) G16B 50/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12041359 | Alshurafa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Nabil I. Alshurafa (Chicago, Illinois); Josiah D. Hester (Evanston, Illinois) |
| ABSTRACT | A camera system includes a camera configured to capture first video of a scene in the form of first image frames. The camera system also includes an infrared sensor configured to capture second video of the scene in the form of second image frames. The system also includes a processor in communication with the camera and the infrared sensor. The processor is configured to obfuscate one or more portions of the scene. |
| FILED | Wednesday, April 27, 2022 |
| APPL NO | 17/730858 |
| ART UNIT | 2481 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 5/73 (20240101) G06T 7/194 (20170101) G06T 2207/10024 (20130101) G06T 2207/10048 (20130101) G06T 2207/20221 (20130101) Pictorial Communication, e.g Television H04N 5/76 (20130101) H04N 5/272 (20130101) H04N 7/18 (20130101) H04N 23/10 (20230101) H04N 23/51 (20230101) H04N 23/54 (20230101) H04N 23/80 (20230101) Original (OR) Class H04N 23/90 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12041796 | Scheuermann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | James Scheuermann (Katonah, New York); Wei Zhao (East Setauket, New York) |
| ABSTRACT | A sensor including a layer of amorphous selenium (a-Se) and at least one charge blocking layer is formed by depositing the charge blocking layer over a substrate prior to depositing the amorphous selenium, enabling the charge blocking layer to be formed at elevated temperatures. Such a process is not limited by the crystallization temperature of a-Se, resulting in the formation of an efficient charge blocking layer, which enables improved signal amplification of the resulting device. The sensor can be fabricated by forming first and second amorphous selenium layers over separate substrates, and then fusing the a-Se layers at a relatively low temperature. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/155446 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/241 (20130101) G01T 1/247 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 2031/0344 (20130101) Organic electric solid-state devices H10K 30/10 (20230201) Original (OR) Class H10K 39/32 (20230201) H10K 39/36 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12035720 | Roeder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey F. Roeder (Brookfield, Connecticut); Melissa A. Petruska (Newtown, Connecticut); Trevor E. James (Plantsville, Connecticut); Thomas J. Spoonmore (Norwalk, Connecticut); Peter C. Van Buskirk (Newtown, Connecticut) |
| ASSIGNEE(S) | Sonata Scientific LLC (Danbury, Connecticut) |
| INVENTOR(S) | Jeffrey F. Roeder (Brookfield, Connecticut); Melissa A. Petruska (Newtown, Connecticut); Trevor E. James (Plantsville, Connecticut); Thomas J. Spoonmore (Norwalk, Connecticut); Peter C. Van Buskirk (Newtown, Connecticut) |
| ABSTRACT | Polymer coatings and surfaces are disclosed with antimicrobial properties. The antimicrobial action is provided by high surface area materials contained within the coating or surface. The high surface area materials may contain photocatalysts that create reactive oxygen species upon exposure to visible light or transition metals that create reactive oxygen species upon exposure to hydrogen peroxide. The high surface area materials may also sorb disinfecting liquids and desorb them over time to provide disinfection. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/343723 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/10 (20130101) A01N 59/06 (20130101) A01N 59/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036003 | Aronoff-Spencer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eliah Aronoff-Spencer (San Diego, California); Tom Kalisky (La Jolla, California); Daniel Johnson (Escondido, California); Alex Grant (San Diego, California); Steve Saggese (San Diego, California) |
| ABSTRACT | A multimodal biometric device is disclosed. An apparatus may include a non-contact imaging system. The non-contact imaging system may include imaging optics, optical illumination optically coupled to the imaging optics, and a configurable body part support to support different body parts at corresponding focal lengths to capture different portions of the different body parts. An apparatus may also include a housing coupled to the imaging optics, the optical illumination, and the configurable body part support. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 17/416319 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) Original (OR) Class A61B 5/0033 (20130101) Image or Video Recognition or Understanding G06V 10/143 (20220101) G06V 10/147 (20220101) G06V 40/15 (20220101) G06V 40/45 (20220101) G06V 40/70 (20220101) G06V 40/1312 (20220101) G06V 40/1347 (20220101) G06V 40/1382 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036078 | Weitekamp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | POLYSPECTRA, INC. (Berkeley, California) |
| ASSIGNEE(S) | POLYSPECTRA, INC. (Berkeley, California) |
| INVENTOR(S) | Raymond A. Weitekamp (Berkeley, California); Aditya Balasubramanian (Berkeley, California) |
| ABSTRACT | The present disclosure relates to a method for generating a dental product or an orthodontic product. The method may comprise (a) providing a mixture comprising (i) a latent ruthenium (Ru) complex; (ii) an initiator; (iii) a sensitizer that sensitizes said initiator; and (iv) at least one polymer precursor; and (b) exposing the mixture to electromagnetic radiation to activate the initiator, wherein upon activation, the initiator reacts with the latent Ru complex to generate an activated Ru complex, which activated Ru complex reacts with the at least one polymer precursor to generate at least a portion of a final product of the dental product or the orthodontic product, wherein the at least the portion of the final product of the dental product or the orthodontic product comprises a polymer generated from the at least one polymer precursor. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 17/399368 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 13/0013 (20130101) Original (OR) Class A61C 13/0019 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 6/62 (20200101) A61K 6/887 (20200101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/35 (20170801) B29C 64/124 (20170801) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 2261/418 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036129 | Howell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brigham Young University (BYU) (Provo, Utah) |
| ASSIGNEE(S) | Brigham Young University (Provo, Utah) |
| INVENTOR(S) | Larry L. Howell (Orem, Utah); Collin Ynchausti (Provo, Utah); Anton E. Bowden (Lindon, Utah); Nathan Brown (Orem, Utah) |
| ABSTRACT | Deployable Euler Spiral Connectors (DESCs) are introduced as compliant deployable flexures that can span gaps between segments in a mechanism and then lay flat when under strain in a stowed position. This paper presents models of Euler spiral beams combined in series and parallel that can be used to design compact compliant mechanisms. Constraints on the flexure parameters of DESCs are also presented. Analytic models developed for the force-deflection behavior and stress were compared to finite element analysis and experimental data. A spinal implant and a linear ratcheting system are presented as illustrative applications of DESCs. |
| FILED | Friday, August 13, 2021 |
| APPL NO | 17/445017 |
| ART UNIT | 3773 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/442 (20130101) Original (OR) Class A61F 2/468 (20130101) A61F 2/4455 (20130101) A61F 2/30942 (20130101) A61F 2002/30522 (20130101) A61F 2002/30943 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036339 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Russell Martin (Baltimore, Maryland); Hai-Quan Mao (Baltimore, Maryland); Sashank Reddy (Baltimore, Maryland); Kevin Colbert (Baltimore, Maryland) |
| ABSTRACT | A composite material can include a gel and at least one nanostructure disposed within the gel. A method for healing a soft tissue defect can include applying a composite material to a soft tissue defect, wherein the composite material includes a gel and a nanostructure disposed within the gel. A method for manufacturing a composite material for use in healing soft tissue defects can include providing a gel and disposing nanofibers within the gel. |
| FILED | Thursday, July 18, 2019 |
| APPL NO | 16/515819 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) Original (OR) Class A61L 27/3633 (20130101) A61L 2300/62 (20130101) A61L 2300/236 (20130101) A61L 2400/06 (20130101) A61L 2430/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036515 | Kumar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Panama) |
| INVENTOR(S) | Manish Kumar (Austin, Texas); Woochul Song (State College, Pennsylvania); Yue-xiao Shen (El Cerrito, California); Chao Lang (State College, Pennsylvania) |
| ABSTRACT | The present invention relates to a thin-film composite (TFC) membrane composition comprising macrocycles. The invention also relates in part to a method of fabricating a TFC membrane and to a method of using the TFC membrane to separate a desired liquid or gas from a liquid or gas mixture. |
| FILED | Wednesday, October 02, 2019 |
| APPL NO | 17/282082 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 67/0006 (20130101) B01D 69/02 (20130101) B01D 69/105 (20130101) B01D 69/125 (20130101) Original (OR) Class B01D 71/56 (20130101) B01D 71/60 (20130101) B01D 71/64 (20130101) B01D 71/68 (20130101) B01D 2325/02 (20130101) B01D 2325/04 (20130101) Acyclic or Carbocyclic Compounds C07C 7/144 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036550 | Haun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Jered Haun (Irvine, California); Xiaolong Qiu (Chula Vista, California); Elliot Hui (Arcadia, California); Amrith Karunaratne (Carson, California); Erik Werner (Irvine, California) |
| ABSTRACT | A microfluidic device uses hydrodynamic shear forces on a sample to improve the speed and efficiency of tissue digestion is disclosed. The microfluidic channels are designed to apply hydrodynamic shear forces at discrete locations on tissue specimens up to 1 cm in length and 1 mm in diameter, thereby accelerating digestion through hydrodynamic shear forces and improved enzyme-tissue contact. The microfluidic digestion device can eliminate or reduce the need to mince tissue samples with a scalpel, while reducing sample processing time and preserving cell viability. Another advantage is that downstream microfluidic operations could be integrated to enable advanced cell processing and analysis capabilities. The device may be used in research and clinical settings to promote single cell-based analysis technologies, as well as to isolate primary, progenitor, and stem cells for use in the fields of tissue engineering and regenerative medicine. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180711 |
| ART UNIT | 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 2200/027 (20130101) B01L 2200/0647 (20130101) B01L 2300/042 (20130101) B01L 2300/0816 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036793 | Iezzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Brian Iezzi (Ann Arbor, Michigan); Max Shtein (Ann Arbor, Michigan); Zahra Afkhami Kheirabadi (Ann Arbor, Michigan); Kira Barton (Ann Arbor, Michigan) |
| ABSTRACT | A method of fabricating a thin film structure includes printing, using an electrohydrodynamic jet (e-jet) printing apparatus, a first layer comprising a first liquid ink, such that the first layer is supported by a substrate, curing the first layer; printing, using the e-jet printing apparatus, a second layer comprising a second liquid ink, such that the second layer is supported by the first layer, and curing the second layer. |
| FILED | Wednesday, June 14, 2023 |
| APPL NO | 18/209942 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/06 (20130101) Original (OR) Class B41J 11/00214 (20210101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/2018 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037251 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Daeyeon Lee (Wynnewood, Pennsylvania); R. Bharath Venkatesh (Philadelphia, Pennsylvania) |
| ABSTRACT | Provided are methods for forming polymer-infiltrated nanoparticle films by using capillary action to draw mobile molecular chains into the pores of a bed of nanoparticles. The chains can spread across the entire bed of nanoparticles. The disclosed methods also provide the formation of patterned polymer-infiltrated nanoparticle film compositions, as well as laterally graded compositions and compositions that feature a polymer gradient through the composition's thickness. Articles can be formed that include a plurality of polymer types infiltrated into the bed of nanoparticles. |
| FILED | Tuesday, April 06, 2021 |
| APPL NO | 17/223546 |
| ART UNIT | 1718 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/286 (20130101) B05D 3/007 (20130101) B05D 5/00 (20130101) B05D 2203/00 (20130101) B05D 2518/10 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/149 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 2383/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037265 | Mayer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marquette University (Milwaukee, Wisconsin) |
| ASSIGNEE(S) | Marquette University (Milwaukee, Wisconsin) |
| INVENTOR(S) | Brooke Mayer (Milwaukee, Wisconsin); Kaushik Venkiteshwaran (Milwaukee, Wisconsin) |
| ABSTRACT | The present invention provides systems and methods for concentrating and recovering phosphate from samples. The method comprises using immobilized PBP for binding phosphate and a desorption solution having a pH of 11 or greater to recover phosphate from a sample when the phosphate is found at very low detection levels. Further systems and method for removing arsenate for water sources is also provided. |
| FILED | Wednesday, January 20, 2021 |
| APPL NO | 17/153471 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/3475 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/286 (20130101) Original (OR) Class C02F 2101/105 (20130101) C02F 2103/34 (20130101) C02F 2303/16 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/00 (20130101) G01N 30/06 (20130101) G01N 30/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037529 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, the State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Ki-Bum Lee (Piscataway, New Jersey); Hudifah Rabie (Piscataway, New Jersey); Nicholas Pasquale (Piscataway, New Jersey); Yixiao Zhang (Piscataway, New Jersey) |
| ABSTRACT | Disclosed herein are embodiments of a composition comprising at least three layers. Layers one and two each either comprises a sensitizer or an emitter, typically a metal ion or a dye, and the third layer may or may not comprise a sensitizer or emitter. Upon exposure to light, such as infrared light, the composition produces visible and/or UV light. The composition may further comprise a capping moiety, a therapeutic agent, an uptake enhancer, a detection moiety that binds to a desired target, a quenching moiety, or a combination thereof. The composition may be a particle, such as a nanoparticle, or it may be a planar composition. Also disclosed are embodiments of a method for using the composition, including, but not limited to, a method for delivering a therapeutic agent, or a method for detecting a target, such as a biological target. |
| FILED | Wednesday, December 30, 2020 |
| APPL NO | 17/137813 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/203 (20130101) A61K 49/0013 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 40/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/02 (20130101) C09K 11/0833 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0696 (20130101) C12N 15/115 (20130101) C12N 2310/16 (20130101) C12N 2500/05 (20130101) C12N 2506/03 (20130101) C12N 2529/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037574 | Kotecha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | O2M Technologies, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | O2M Technologies, LLC (Chicago, Illinois) |
| INVENTOR(S) | Mrignayani Kotecha (Chicago, Illinois); Boris Meerovich Epel (Chicago, Illinois); Eliyas Siddiqui (Chicago, Illinois); Safa Hameed (Chicago, Illinois) |
| ABSTRACT | A method includes placing a sample of cells, tissue, or an organ into an oxygen imaging system, circulating a humidified gas mixture around the tissue or organ, circulating conditioned air through the oxygen imaging system to maintain a temperature around the sample, and acquiring a three-dimensional oxygen map of the sample. The oxygen map provides a quantitative measure of cell viability and functionality. |
| FILED | Friday, November 10, 2023 |
| APPL NO | 18/506801 |
| ART UNIT | 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 29/24 (20130101) C12M 41/12 (20130101) C12M 41/46 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037594 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Ling Li (Starkville, Mississippi); Eve Syrkin Wurtele (Ames, Iowa) |
| ABSTRACT | Method of increasing protein content in a eukaryotic cell comprising an NF-YC4 gene comprising modifying the transcriptional repressor binding site; method of producing a plant with increased protein content comprising crossing and selecting for increased protein content; method of increasing resistance to a pathogen or a pest in a plant cell or plant comprising an NF-YC4 gene comprising modifying the transcriptional repressor binding site, alone or in further combination with expressing QQS in the plant cell or plant; method for producing a plant with increased resistance to a pathogen or a pest comprising crossing and selecting for increased resistance to the pathogen or the pest; a cell, collection of cells, tissue, organ, or organism, such as a plant, in which the NF-YC4 gene comprises a promoter comprising a transcriptional repressor binding site that has been modified so that the transcriptional repressor cannot prevent transcription of the NF-YC4; plants and hybrids thereof; and seeds. |
| FILED | Monday, November 21, 2022 |
| APPL NO | 18/057439 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8205 (20130101) C12N 15/8216 (20130101) C12N 15/8241 (20130101) C12N 15/8247 (20130101) C12N 15/8251 (20130101) Original (OR) Class C12N 15/8279 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037629 | Chu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Kung-Hui Chu (College Station, Texas); Ry Young (College Station, Texas); Jason Gill (College Station, Texas) |
| ABSTRACT | In an embodiment, the present disclosure pertains to an oleaginous bacterium. In some embodiments, the oleaginous bacterium includes lipids and at least one exogenous and inducible gene. In some embodiments, the exogenous and inducible gene encodes at least one protein capable of inducing lysis in the oleaginous bacterium to release the lipids. In an addition embodiment, the present disclosure pertains to a method of releasing lipids into an environment. In general, the method includes one or more of the following steps of: (1) introducing at least one oleaginous bacterium of the present disclosure to the environment; and (2) inducing expression of at least one exogenous gene in the oleaginous bacterium to thereby induce the expression of at least one protein. In some embodiments, the protein facilitates the lysis of the oleaginous bacterium and release of the lipids into the environment. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 17/407939 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6463 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/365 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038309 | Chung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Jae-Hyun Chung (Seattle, Washington); Sang-Gyeun Ahn (Seattle, Washington); Tianyi Li (Seattle, Washington); Zhongjie Qian (Seattle, Washington); Vigneshwar Sakthivelpathi (Seattle, Washington) |
| ABSTRACT | A capacitive sensor including an electrically conductive material, and a single electrode applied with positive potential, wherein the distance between the single electrode and the electrically conductive material determines the spherical radius for a proximity sensing range. |
| FILED | Thursday, December 29, 2022 |
| APPL NO | 18/091219 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/24 (20130101) Original (OR) Class Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 22/02 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038361 | Bhattacharya |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TEXAS TECH UNIVERSITY SYSTEM (Lubbock, Texas) |
| ASSIGNEE(S) | Texas Tech University System (Lubbock, Texas) |
| INVENTOR(S) | Sukalyan Bhattacharya (Lubbock, Texas) |
| ABSTRACT | Disclosed is a system and method for determination of the viscoelastic properties of a viscoelastic substance based on the type of non-mechanical forces which drive the viscoelastic substance inside a channel. These forces may comprise capillary, gravitational, electric, magnetic, or any other type where neither a pump nor any relative velocity between solid surfaces is needed to induce the transport of fluid medium. As a result, the design of the system remains simple, and the system is capable of yielding results devoid of noise produced by mechanical forcing. The present disclosure a general analysis describing extraction of viscoelastic properties by observing flow-systems driven by any non-mechanical means, including capillary force and electro-osmotic force. Such time-dependent penetration depth may be recorded by optical, electrical or mechanical means and may further include the use of a computing device. |
| FILED | Friday, June 22, 2018 |
| APPL NO | 16/626168 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 11/04 (20130101) Original (OR) Class G01N 2203/0014 (20130101) G01N 2203/0071 (20130101) G01N 2203/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038407 | Herr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Amy E. Herr (Berkeley, California); Lin He (Berkeley, California); Andrew J. Modzelewski (Berkeley, California); Elisabet Rosàs-Canyelles (Berkeley, California) |
| ABSTRACT | Dual nucleic acid and protein isoform measurements are performed on low starting cell numbers (e.g. equivalent to the number of blastomeres composing early embryonic development stages (morula and blastocysts)), comprising integrating fractionation polyacrylamide gel electrophoresis (fPAGE) of 10-100 cells with off-chip analysis of nucleic acids in the nuclei. |
| FILED | Monday, May 24, 2021 |
| APPL NO | 17/327806 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/40 (20130101) C08J 2333/26 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/1545 (20130101) Compositions of Macromolecular Compounds C08L 33/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44747 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038608 | Bandyopadhyay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Saumil Bandyopadhyay (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | The next-generation of optoelectronic systems will require efficient optical signal transfer between many discrete photonic components integrated onto a single substrate. While modern assembly processes can easily integrate thousands of electrical components onto a single board, photonic assembly is far more challenging due to the wavelength-scale alignment tolerances required. Here we address this problem by introducing a self-aligning photonic coupler insensitive to x, y, z displacement and angular misalignment. The self-aligning coupler provides a translationally invariant evanescent interaction between waveguides by intersecting them at an angle, which enables a lateral and angular alignment tolerance fundamentally larger than non-evanescent approaches such as edge coupling. This technology can function as a universal photonic connector interfacing photonic integrated circuits and microchiplets across different platforms. For example, it can be used in a self-aligning photonic circuit board that can be assembled more easily, with larger misalignment tolerances, than other complex optoelectronic systems. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470803 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) Original (OR) Class G02B 2006/12147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038667 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts); SHEFFIELD HALLAM UNIVERSITY (Sheffield, United Kingdom) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts); SHEFFIELD HALLAM UNIVERSITY (Sheffield, United Kingdom) |
| INVENTOR(S) | Shu Yang (Swarthmore, Pennsylvania); Yu Xia (Swarthmore, Pennsylvania); Timothy J. Atherton (Boston, Massachusetts); Douglas J. Cleaver (Chesterfield, United Kingdom); Andrew A. Debenedictis (Somerville, Massachusetts); Dae Seok Kim (Philadelphia, Pennsylvania) |
| ABSTRACT | Multi-state switchability is highly desirable in optoelectronic devices. For liquid crystal (LC) based devices, the stability of any configuration is achieved through a balance between imposed interactions and the LC's orientational elasticity. In most cases, the latter acts to resist deformation. By combining surface topography and chemical patterning, provided here are the effects of saddle-splay orientational elasticity, a property that, despite being intrinsic to all LCs, is routinely suppressed. Utilizing theory and continuum elastic calculations, provided here are example conditions for which, even using generic, achiral LC materials, spontaneously broken surface symmetries develop. Also provided are multi-stable devices in which a weak, but directional, applied field switches between spontaneously-polar surface state domains. The disclosed approach is useful in low-field and fast-switching optoelectronic devices, beyond those attainable by current technologies. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 17/435407 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/31 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038767 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Jane Huang (South Bend, Indiana); Michael Vierhauser (South Bend, Indiana); Ankit Agrawal (South Bend, Indiana) |
| ABSTRACT | A method for configuring a multiple autonomous drone mission includes displaying, a plurality of queries on a display of the computing device. The method further includes receiving, via a user interface, a plurality of inputs responsive to the plurality of queries. At least a first input of the plurality of inputs specifies a type of mission to be performed and at least a second input of the plurality of inputs specifies a geographical area in which a mission to be performed will be carried out. The method further includes automatically determining, based on the plurality of inputs, an initial location to move to for each of a plurality of drones available for implementing the mission. The method further includes automatically determining, based on the plurality of inputs, a series of tasks for each of the plurality of drones. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 17/571449 |
| ART UNIT | 3669 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Unmanned aerial vehicles [UAV]; equipment therefor B64U 2101/00 (20230101) B64U 2101/30 (20230101) Systems for Controlling or Regulating Non-electric Variables G05D 1/104 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/029 (20180201) H04W 4/30 (20180201) H04W 4/90 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039073 | Moataz |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MongoDB, Inc. (New York, New York) |
| ASSIGNEE(S) | MongoDB, Inc. (New York, New York) |
| INVENTOR(S) | Tarik Moataz (North Providence, Rhode Island) |
| ABSTRACT | Methods and system implement solutions for integrating encryption and emulation into native database formats and/or architectures. “Native” database is used to describe a database that has not been designed for end to end encryption, an off the shelf database deployment, and/or a commercially available database. According to some embodiments, various encryption systems and methods employ emulation operations to enable a native database and native database functions to leverage full encryption primitives. Various aspects integrate emulation operations into standard database implementations, where the emulation enables native database functions to operate on entirely encrypted data. |
| FILED | Friday, January 07, 2022 |
| APPL NO | 17/570730 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/213 (20190101) G06F 21/6227 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039091 | Talukdar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Jonti Talukdar (Durham, North Carolina); Krishnendu Chakrabarty (Durham, North Carolina) |
| ABSTRACT | An integrated circuit (IC) protection circuit for an IC includes a controller with a barrier finite state machine (FSM) having a key sequence input that unlocks the controller; and a signal scrambler coupled to receive at least two initialization inputs and a primary input path and output a signal to the IC, wherein at least one initialization input of the at least two initialization inputs is based on an output of the barrier FSM. The IC protection circuit can further include a dynamic authentication circuit coupled to receive the output of the barrier finite state machine and output a signal to the signal scrambler for one of the at least two initialization inputs. The dynamic authentication circuit can be formed of a dynamic sequence generator and a dynamic sequence authenticator, each formed of one or more reconfigurable linear feedback shift registers, and a comparator. |
| FILED | Thursday, October 07, 2021 |
| APPL NO | 17/496055 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/75 (20130101) Original (OR) Class Static Stores G11C 29/36 (20130101) G11C 2029/3602 (20130101) Pulse Technique H03K 19/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039406 | Endres et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Manuel Endres (Pasadena, California); Alexandre Cooper-Roy (Downey, California); Jacob P. Covey (Pasadena, California); Ivaylo S. Madjarov (Pasadena, California); Adam L. Shaw (Pasadena, California); Vladimir Schkolnik (Pasadena, California); Jason R. Williams (Castaic, California); Joonhee Choi (Pasadena, California) |
| ABSTRACT | An apparatus useful for creating and measuring states of an entangled system, comprising a pair of interacting multi-level systems, each of systems comprising a state |g>, a state |r>, and state |r*>. One or more first electromagnetic fields excite a first transition between the ground state |g> and the state |r> to create an entangled system. One or more second electromagnetic fields are tuned between the state |r> and the intermediate state |r*> so that any population of the systems in |r*> are dark to a subsequent detection of a population in the systems in |g>, providing a means to distinguish the entangled system in the state |g> and the entangled system in the state |r>. In one or more examples, the systems comprise neutral Rydberg atoms. |
| FILED | Monday, March 06, 2023 |
| APPL NO | 18/178840 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/006 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/003 (20130101) Transmission H04B 10/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039433 | Karanth et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ohio University (Athens, Ohio) |
| ASSIGNEE(S) | Ohio University (Athens, Ohio) |
| INVENTOR(S) | Avinash Karanth (Canal Winchester, Ohio); Kyle Shiflett (Chillicothe, Ohio) |
| ABSTRACT | Processing elements for neural network accelerators, and methods of operating the processing elements. Each of a plurality of synapse lanes outputs an electrical signal indicative of a value of a synapse. Each electrical signal is received by a respective optical AND unit including an optical microring resonator that selectively couples an optical signal indicative of the value of an input neuron based at least in part on the received electrical signal. The output of each optical AND unit is provided to either an electrical multiply and accumulate unit, or a respective interferometer of a plurality of interferometers. The interferometers are arranged in series so that optical signals are sequentially summed and shifted by each interferometer. The last interferometer outputs a shifted and accumulated sum of the outputs received from the optical AND units. In either case, the accumulated sum may then be used to generate an output neuron. |
| FILED | Thursday, February 18, 2021 |
| APPL NO | 17/178563 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Electric Digital Data Processing G06F 5/01 (20130101) G06F 7/50 (20130101) G06F 7/523 (20130101) G06F 7/5443 (20130101) G06F 9/5027 (20130101) Computer Systems Based on Specific Computational Models G06N 3/048 (20230101) G06N 3/063 (20130101) Original (OR) Class G06N 3/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039765 | Buckler et al. |
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| FUNDED BY |
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| APPLICANT(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| INVENTOR(S) | Andrew J. Buckler (Boston, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts); Mark A. Buckler (Wenham, Massachusetts); Vladimir Valtchinov (Boston, Massachusetts); David S. Paik (Moon Bay, California) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Monday, May 01, 2023 |
| APPL NO | 18/309903 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/24 (20230101) G06F 18/211 (20230101) G06F 18/2148 (20230101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 3/00 (20130101) G06T 5/73 (20240101) G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 2207/10048 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10101 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/30096 (20130101) G06T 2207/30104 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) Original (OR) Class G06V 10/764 (20220101) G06V 20/69 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040140 | Ma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Biwu Ma (Tallahassee, Florida); Qingquan He (Tallahassee, Florida) |
| ABSTRACT | Methods of passivating surfaces, composite materials, and electronic devices including the composite materials. The composite materials can include a passivated film, such as a metal halide perovskite passivated with an organic dye. The electronic devices may include solar cells. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/684991 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/0036 (20130101) H01G 9/2009 (20130101) Original (OR) Class Organic electric solid-state devices H10K 30/88 (20230201) H10K 85/30 (20230201) H10K 85/655 (20230201) H10K 85/657 (20230201) H10K 85/6572 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040677 | Bird |
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| FUNDED BY |
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| APPLICANT(S) | Portland State University (Portland, Oregon) |
| ASSIGNEE(S) | Portland State University (Portland, Oregon) |
| INVENTOR(S) | Jonathan Bird (Portland, Oregon) |
| ABSTRACT | The disclosure presents configurations and analyses of magnetic gears, which may be used in the second stage of a multistage magnetically geared generator for a marine hydrokinetic generator application and/or other applications as described. In order to reduce field harmonics and maximize the torque density, a Halbach rotor topology is utilized. One feature of the disclosed configuration is a unique magnet arrangement that enables inner and outer Halbach rotor magnets to be more easily assembled, even with dimensional tolerance inaccuracies. The disclosed Halbach magnet rotor topology makes use of the internal magnet forces to retain the magnets in position, and the disclosed configuration also helps with the assembly process. |
| FILED | Monday, September 28, 2020 |
| APPL NO | 17/035471 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 49/102 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040897 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia) |
| INVENTOR(S) | Ke Wang (Alexandria, Virginia); Ahmed Louri (Vienna, Virginia) |
| ABSTRACT | A proactive fault-tolerant scheme which improves performance and energy efficiency for NoCs. The fault-tolerant scheme allows routers to switch among several different fault-tolerant operations. Each operation mode has different trade-offs among fault-tolerant capability, retransmission traffic, latency, and energy efficiency. Another example provides a proactive, dynamic control policy to balance and optimize the dynamic interactions and trade-offs. The example control policy uses example machine learning algorithm called reinforcement learning (RL). The example RL-based controller independently observes a set of NoC system parameters at runtime, and over time they evolve optimal per-router control policies. By automatically and optimally switching among the four fault-tolerant modes, the trained control policy results in minimizing system level network latency and maximizing energy efficiency while detecting and correcting errors. |
| FILED | Wednesday, August 21, 2019 |
| APPL NO | 16/547297 |
| ART UNIT | 2411 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 13/4027 (20130101) Coding; Decoding; Code Conversion in General H03M 13/2906 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0044 (20130101) H04L 1/0057 (20130101) Original (OR) Class H04L 1/1896 (20130101) H04L 45/08 (20130101) H04L 47/125 (20130101) H04L 49/15 (20130101) H04L 49/90 (20130101) H04L 49/557 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12041359 | Alshurafa et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Nabil I. Alshurafa (Chicago, Illinois); Josiah D. Hester (Evanston, Illinois) |
| ABSTRACT | A camera system includes a camera configured to capture first video of a scene in the form of first image frames. The camera system also includes an infrared sensor configured to capture second video of the scene in the form of second image frames. The system also includes a processor in communication with the camera and the infrared sensor. The processor is configured to obfuscate one or more portions of the scene. |
| FILED | Wednesday, April 27, 2022 |
| APPL NO | 17/730858 |
| ART UNIT | 2481 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 5/73 (20240101) G06T 7/194 (20170101) G06T 2207/10024 (20130101) G06T 2207/10048 (20130101) G06T 2207/20221 (20130101) Pictorial Communication, e.g Television H04N 5/76 (20130101) H04N 5/272 (20130101) H04N 7/18 (20130101) H04N 23/10 (20230101) H04N 23/51 (20230101) H04N 23/54 (20230101) H04N 23/80 (20230101) Original (OR) Class H04N 23/90 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12035764 | Ames |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Blauer Manufacturing Company, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Blauer Manufacturing Company, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Thomas W Ames (Newton, Massachusetts) |
| ABSTRACT | A zipper path for a non-encapsulating hazardous materials protection suit that has a first section extending generally vertically on the torso and a second section extending generally vertically on the torso, each section curving outwardly to a neck section that circles the suit neck. Segments of the first and second sections are less than the width of the neck section apart so that only a small number of snips from scissors is needed to sever the suit along a cut line that extends horizontally between the segments. One or both sections can extend down to a leg for ease in doffing the suit. Optionally, the zipper has a protective overlap. To doff the suit, the zipper is disengaged, the suit is cut with scissors at the cut line to separate the suit bottom from the hood, and the suit bottom is removed, followed by the hood. |
| FILED | Wednesday, December 14, 2022 |
| APPL NO | 18/065818 |
| ART UNIT | 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/02 (20130101) Original (OR) Class A41D 13/0005 (20130101) Buttons, Pins, Buckles, Slide Fasteners, or the Like A44B 19/32 (20130101) Devices, Apparatus or Methods for Life-saving A62B 17/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036187 | Dixon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southwest Research Institute (San Antonio, Texas) |
| ASSIGNEE(S) | SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas) |
| INVENTOR(S) | Hong Dixon (Helotes, Texas); Joseph A. McDonough (Helotes, Texas) |
| ABSTRACT | The present disclosure is directed at compositions of dimethyl trisulfide (DMTS) suitable for use for treatment of cyanide intoxication. The compositions show particularly useful stability such that the DMTS remains stable for therapeutic use at the identified time periods. The compositions are therefore particularly suitable for use in autoinjectors. |
| FILED | Tuesday, March 10, 2020 |
| APPL NO | 16/814988 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/1075 (20130101) A61K 31/10 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036669 | Paine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Apptronik, Inc. (Austin, Texas) |
| ASSIGNEE(S) | Apptronik, Inc. (Austin, Texas) |
| INVENTOR(S) | Nicholas Arden Paine (Austin, Texas); Jonas Fox (Austin, Texas) |
| ABSTRACT | An exoskeleton device in accordance with the present disclosure may generally include a series elastic actuator (SEA), a slider-crank mechanism and a four bar linkage mechanism. The SEA includes a motor and a ball screw coupled to a shaft of the motor via a shaft coupler, which transfers rotational motion of the shaft directly to the ball screw. The slider-crank mechanism includes a ball nut and a crank. As the ball screw rotates, the ball nut converts rotational motion of the ball screw into linear motion of the ball nut to drive the crank. The crank converts linear motion of the ball nut back into rotational motion at the input of the four bar linkage mechanism. The four bar linkage mechanism is coupled to an output of the crank and configured to provide a complex motion profile that emulates kinematics of a wearer's joint. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/979057 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) A61H 2201/123 (20130101) A61H 2201/165 (20130101) A61H 2201/1215 (20130101) A61H 2201/1436 (20130101) A61H 2201/1628 (20130101) A61H 2201/1642 (20130101) A61H 2201/5058 (20130101) A61H 2205/088 (20130101) A61H 2205/102 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037347 | Peterson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Chemical Biological Center, APG, MD (APG, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Gregory W. Peterson (Belcamp, Maryland); Thomas H. Epps, III (Newark, Delaware) |
| ABSTRACT | A composition having the structure of formula I: [R—Ar—(COOH)2]x[Ar—(COOH)3]2-xM32+ (I) is provided where M is Mn, Cu, Co, Fe, Zn, Cd, Ni, or Pt; R is a bromine, nitro, a primary amine, C1-C4 alkyl secondary amine, C1-C4 alkyl oxy, Br—(C1-C4 alkyl), NO2—(C1-C4 alkyl), a mercaptan, and reaction products of any of the aforementioned with acyl chlorides of the formulas: CH3(CH2)mC(O)Cl, or CH3(CH(C1-C4 alkyl)CH2)mC(O)Cl, or CH3(CH2)m-Ph-(CH2)pC(O)Cl, where Ph is a C6 phenyl or C6 phenyl with one or more hydrogens replaced with F, C1-C4 fluoroalkyl, or C1-C4 perfluoroalkyl; m is independently in each occurrence an integer of 0 to 12 inclusive; p is an integer of 0 to 36 inclusive, to form an amide, a thioamide, or an ester; Ar is a 1,3,5-modified phenyl, and 1.4>×>0. A process of synthesis thereof and the use to chemically modify a gaseous reactant are also provided. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/957183 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/58 (20130101) B01D 53/62 (20130101) B01D 67/0079 (20130101) B01D 69/12 (20130101) B01D 71/022 (20130101) B01D 71/82 (20130101) B01D 2257/93 (20130101) B01D 2257/406 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) B01D 2323/39 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037371 | O'Malley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michelle O'Malley (Santa Barbara, California); Kevin Solomon (Lafayette, Indiana); Charles Haitjema (San Jose, California) |
| ABSTRACT | Provided herein are novel proteins and protein domains from newly discovered anaerobic fungal species. The anaerobic fungal species have unique enzymatic capabilities, including the ability to digest diverse lignocellulosic biomass feedstocks and to synthesize secondary metabolites. The scope of the invention encompasses novel engineered proteins comprising glycoside hydrolase enzymes, dockerin domains, carbohydrate binding domains, and polyketide synthase enzymes. The invention further encompasses artificial cellulosomes comprising novel proteins and domains of the invention. The scope of the invention further includes novel nucleic acid sequences coding for the engineered proteins of the invention, and methods of using such engineered organisms to degrade lignocellulosic biomass and to create polyketides. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/321941 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/37 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/00 (20130101) C12N 9/0006 (20130101) C12N 9/24 (20130101) C12N 15/52 (20130101) C12N 15/70 (20130101) C12N 15/81 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) C12P 21/02 (20130101) C12P 39/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037404 | Ip et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Hong Kong University of Science and Technology (Hong Kong, China PRC); THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (Hong Kong, China PRC) |
| INVENTOR(S) | Nancy Yuk-Yu Ip (Hong Kong, China PRC); Kit Yu Fu (Hong Kong, China PRC); Wing Yu Fu (Hong Kong, China PRC); Dimiter S. Dimitrov (Frederick, Maryland); Tianlei Ying (Frederick, Maryland) |
| ABSTRACT | The present invention provides new, fully human EphA4 monoclonal antibodies with distinct binding characteristics. Also disclosed are antigen binding fragments of these antibodies, bispecific forms of these antibodies, and conjugates of these antibodies. In addition, nucleic acids encoding these antibodies, antigen binding fragments, bispecific antibodies and conjugates are disclosed. These monoclonal antibodies, antigen binding fragments, bispecific antibodies, conjugates, nucleic acids and vector are of use for identifying and treating a subject with a disease or condition involving abnormal EphA4-mediated signaling. |
| FILED | Monday, February 15, 2021 |
| APPL NO | 17/175879 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) A61P 35/00 (20180101) Peptides C07K 14/71 (20130101) C07K 16/2866 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 33/57492 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037472 | Rushing |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Texas Research International, Inc. (Austin, Texas) |
| ASSIGNEE(S) | TEXAS RESEARCH INTERNATIONAL, INC. (Austin, Texas) |
| INVENTOR(S) | Rock Rushing (Spicewood, Texas) |
| ABSTRACT | A matrix resin composition for fiber reinforced composite materials is described. The resin is thermosetting and achieves a glass transition temperature of at least 177° C. (Tg), obtained by curing under anaerobic conditions at room temperature. The matrix resin will streamline composite fabrication processes by eliminating the need for heating during the cure process. The implications of this development are significant in terms of the ease of use and elimination of procedural steps. While the resin system was developed specifically for vacuum bagging, it is expected to be viable for other composite fabrication methods including resin transfer molding (RTM) and vacuum-assisted resin transfer molding (VARTM). The resin system is viable for use with carbon fiber reinforcements to fabricate laminates at least 0.20 inches thick. The resulting laminates have low porosity and mechanical properties equivalent to those prepared with common epoxy matrix resins. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 17/409185 |
| ART UNIT | 1759 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 73/02 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/06 (20130101) Original (OR) Class C08J 5/10 (20130101) C08J 5/042 (20130101) C08J 5/243 (20210501) C08J 5/248 (20210501) C08J 5/249 (20210501) C08J 2363/10 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/14 (20130101) C08K 5/14 (20130101) C08K 5/14 (20130101) C08K 5/18 (20130101) C08K 5/18 (20130101) C08K 5/18 (20130101) C08K 5/0025 (20130101) C08K 5/43 (20130101) C08K 5/43 (20130101) C08K 5/43 (20130101) C08K 5/47 (20130101) C08K 5/0091 (20130101) C08K 5/544 (20130101) Compositions of Macromolecular Compounds C08L 33/08 (20130101) C08L 33/08 (20130101) C08L 33/08 (20130101) C08L 33/10 (20130101) C08L 33/10 (20130101) C08L 33/10 (20130101) C08L 63/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037639 | Abudayyeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Omar Abudayyeh (Cambridge, Massachusetts); James Joseph Collins (Cambridge, Massachusetts); Jonathan Gootenberg (Cambridge, Massachusetts); Feng Zhang (Cambridge, Massachusetts); Eric S. Lander (Cambridge, Massachusetts) |
| ABSTRACT | The embodiments disclosed herein utilized RNA targeting effectors to provide a robust CRISPR-based diagnostic with attomolar sensitivity. Embodiments disclosed herein can detect broth DNA and RNA with comparable levels of sensitivity and can differentiate targets from non-targets based on single base pair differences. Moreover, the embodiments disclosed herein can be prepared in freeze-dried format for convenient distribution and point-of-care (POC) applications. Such embodiments are useful in multiple scenarios in human health including, for example, viral detection, bacterial strain typing, sensitive genotyping, and detection of disease-associated cell free DNA. |
| FILED | Monday, February 25, 2019 |
| APPL NO | 16/285128 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) C12N 2310/16 (20130101) C12N 2310/20 (20170501) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6811 (20130101) C12Q 1/6816 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6876 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/00 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037910 | Strock et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Christopher W. Strock (Kennebunk, Maine); Enzo DiBenedetto (Berlin, Connecticut) |
| ABSTRACT | A seal comprises a housing. A coating has at least two layers with a bond layer to be positioned between a housing and a second hard layer. The second hard layer is formed to be harder than the bond layer. The bond layer has a bond strength greater than or equal to 200 psi and less than or equal to 2000 psi. A gas turbine engine, and a method of forming a coating layer are also disclosed. |
| FILED | Monday, December 23, 2019 |
| APPL NO | 16/724865 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/134 (20160101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/12 (20130101) F01D 11/08 (20130101) Original (OR) Class F01D 11/12 (20130101) F01D 25/24 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/31 (20130101) F05D 2230/90 (20130101) F05D 2300/173 (20130101) F05D 2300/212 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038040 | Gald et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Tewksbury, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Tewksbury, Massachusetts) |
| INVENTOR(S) | Matthew Gald (Tucson, Arizona); Stephen J. Forgacs (Tucson, Arizona); Dan L. Reller (Vail, Arizona); Dean J. Cornelius (Tucson, Arizona) |
| ABSTRACT | A hinge includes internal on-axis stopping mechanisms that cause the hinge to shear and break at an on-axis weakened region of the hinge when rotation of the hinge reaches a predetermined angle with a specified torsional load. The on-axis configuration is compact, has minimal impact on the outer mold line (OML) of the object to which it is mounted both pre and post detachment and allows for accurate tailoring of the torsional load that will detach the hinge. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 17/348371 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 11/10 (20130101) Original (OR) Class F16C 11/12 (20130101) F16C 11/045 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 15/36 (20130101) Technical Subjects Covered by Former US Classification Y10T 403/32591 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038179 | Turney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Joseph Turney (Amston, Connecticut); Christopher Britton Greene (Hebron, Connecticut); Peter A T Cocks (South Glastonbury, Connecticut); Andrzej Ernest Kuczek (Bristol, Connecticut); James M. Donohue (Glastonbury, Connecticut) |
| ABSTRACT | A combustor for a detonation engine includes a radially outer wall extending along an axis; a radially inner wall extending along the axis, wherein the radially inner wall is positioned at least partially within the radially outer wall to define an annular detonation chamber having an inlet for fuel and oxidant and an outlet; a cooling flow passage defined along at least one of the radially outer wall and the radially inner wall and comprising at least two axially spaced cooling flow passage sections, whereby a different cooling rate can be implemented in the at least two axially spaced cooling flow passage sections. |
| FILED | Friday, April 09, 2021 |
| APPL NO | 17/226444 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Jet-propulsion Plants F02K 7/02 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/25 (20130101) Methods or apparatus for combustion using fluid fuel or Solid Fuel Suspended In Air F23C 15/00 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) F23R 7/00 (20130101) Original (OR) Class F23R 2900/03043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038350 | Nemanick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | Eric Joseph Nemanick (Santa Monica, California); Robert G. Will (Redondo Beach, California) |
| ABSTRACT | An apparatus for detecting leaks in a battery includes a plurality of cells, each which include a pair of conductive leads bracketing a polymer seal, and a wireless measurement and communication chip (“chip”) configured to perform capacitive measurement, showing a change in capacitance when bridged by ionically conductive species or when a wick is suffused with an electrolyte. |
| FILED | Monday, April 04, 2022 |
| APPL NO | 17/713142 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038465 | Fancher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The MITRE Corporation (McLean, Virginia); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Charlie Fancher (McLean, Virginia); Bonnie L. Marlow (McLean, Virginia); Kathryn Nicolich (McLean, Virginia); Kelly Backes (McLean, Virginia); Neel Malvania (McLean, Virginia); Kevin Christopher Cox (Gate City, Virginia); David Henry Meyer (Burtonsville, Maryland); Paul D. Kunz (Austin, Texas); Joshua Cartwright Hill (Silver Spring, Maryland); William Knox Holland (Berkeley, California) |
| ABSTRACT | A system for automatically locking a control laser in a Rydberg atomic sensor may comprise an atomic vapor cell, a probe laser configured to excite the atoms in the atomic vapor cell to an intermediate energy state, and a control laser configured to excite the one or more atoms in the atomic vapor cell from the intermediate energy state to a higher energy state. The light generated by the control laser may be dithered at a pre-determined frequency. The system further comprises a photodiode configured to convert light received from the vapor cell into an electrical signal, a lock-in amplifier configured to generate an error signal based on the electrical signal received from the photo diode and a received reference oscillation frequency, and a servo configured to receive the generated error signal from the lock-in amplifier and adjust a frequency of the control laser based on the received error signal. |
| FILED | Friday, March 11, 2022 |
| APPL NO | 17/693036 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 29/14 (20130101) G01R 29/0885 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038530 | Kuzdeba et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Scott A Kuzdeba (Hollis, New Hampshire); Brandon P. Hombs (Merrimack, New Hampshire); Daniel Massar (Bedford, New Hampshire) |
| ABSTRACT | A method of assessing the effectiveness of an electronic countermeasure (ECM) applied against an unknown, ambiguous, or unresponsive radar threat includes monitoring changes in a radar-associated factor while applying the ECM and determining if the ECM is disrupting the hostile radar. The radar-associated factor can be a weapon that is controlled by the radar threat, and assessing the ECM can include determining whether the weapon is misdirected due to applying the ECM. Or the radar-associated factor can be a feature of an RF waveform emitted by the radar threat, and assessing the ECM can include determining if the feature is changed due to applying the ECM. Continuous changes in the feature can indicate unsuccessful attempts to mitigate the ECM. Return of the feature to a pre-threat state can indicate disruption of the radar. The ECM can be selected from a library of countermeasures pre-verified as effective against known threats. |
| FILED | Friday, November 20, 2020 |
| APPL NO | 16/953579 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/021 (20130101) G01S 7/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038608 | Bandyopadhyay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Saumil Bandyopadhyay (Cambridge, Massachusetts); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | The next-generation of optoelectronic systems will require efficient optical signal transfer between many discrete photonic components integrated onto a single substrate. While modern assembly processes can easily integrate thousands of electrical components onto a single board, photonic assembly is far more challenging due to the wavelength-scale alignment tolerances required. Here we address this problem by introducing a self-aligning photonic coupler insensitive to x, y, z displacement and angular misalignment. The self-aligning coupler provides a translationally invariant evanescent interaction between waveguides by intersecting them at an angle, which enables a lateral and angular alignment tolerance fundamentally larger than non-evanescent approaches such as edge coupling. This technology can function as a universal photonic connector interfacing photonic integrated circuits and microchiplets across different platforms. For example, it can be used in a self-aligning photonic circuit board that can be assembled more easily, with larger misalignment tolerances, than other complex optoelectronic systems. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470803 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) Original (OR) Class G02B 2006/12147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038796 | Blankenship et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
| ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
| INVENTOR(S) | Joshua Blankenship (Centerburg, Ohio); James W. Walsh (Columbus, Ohio) |
| ABSTRACT | Adaptive cooling system and methods, docking stations for electronic devices, and systems using the same are described. In embodiments the active cooling systems include a controller that compares a detected temperature of at least a component of a first electronic device to a first temperature threshold (T1D1) for the first electronic device. When the first temperature is ≥T1D1, the controller may issue a control signal that causes a cooling system for a second electronic device to operate at a defined duty level. In embodiments the adaptive cooling systems are incorporated into equipment for a vehicle, such as a vehicle center console. The docking stations may function as a battery eliminator and/or an uninterruptible power supply, and may include a mount, a power connector, and optionally a data connection, which may couple to corresponding device power and device data connections of an electronic device that is coupled to the mount. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 17/680699 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electric Digital Data Processing G06F 1/188 (20130101) G06F 1/203 (20130101) Original (OR) Class G06F 1/1632 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20209 (20130101) H05K 7/20909 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038868 | Hornung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Bryan Hornung (Plano, Texas); Douglas Vanesko (Dallas, Texas); David Patrick (McKinney, Texas) |
| ABSTRACT | Devices and techniques for loading contexts in a coarse-grained reconfigurable array processor are described herein. A system or apparatus may include context load circuitry operable to load context for a coarse-grained reconfigurable array processor, where the context load circuitry is configured to: (a) receive a kernel identifier; (b) access a first registry to obtain a context mask base address; (c) determine a context mask address from the context mask base address and the kernel identifier; (d) access a second registry to obtain a context state base address; (e) determine a context state address from the context state base address and the kernel identifier; (f) use a context mask at the context mask address to determine corresponding active context state; and (g) load the corresponding active context state into the coarse-grained reconfigurable array processor. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/899714 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30018 (20130101) G06F 15/80 (20130101) Original (OR) Class G06F 15/7867 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039406 | Endres et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Manuel Endres (Pasadena, California); Alexandre Cooper-Roy (Downey, California); Jacob P. Covey (Pasadena, California); Ivaylo S. Madjarov (Pasadena, California); Adam L. Shaw (Pasadena, California); Vladimir Schkolnik (Pasadena, California); Jason R. Williams (Castaic, California); Joonhee Choi (Pasadena, California) |
| ABSTRACT | An apparatus useful for creating and measuring states of an entangled system, comprising a pair of interacting multi-level systems, each of systems comprising a state |g>, a state |r>, and state |r*>. One or more first electromagnetic fields excite a first transition between the ground state |g> and the state |r> to create an entangled system. One or more second electromagnetic fields are tuned between the state |r> and the intermediate state |r*> so that any population of the systems in |r*> are dark to a subsequent detection of a population in the systems in |g>, providing a means to distinguish the entangled system in the state |g> and the entangled system in the state |r>. In one or more examples, the systems comprise neutral Rydberg atoms. |
| FILED | Monday, March 06, 2023 |
| APPL NO | 18/178840 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/006 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/003 (20130101) Transmission H04B 10/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040140 | Ma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Biwu Ma (Tallahassee, Florida); Qingquan He (Tallahassee, Florida) |
| ABSTRACT | Methods of passivating surfaces, composite materials, and electronic devices including the composite materials. The composite materials can include a passivated film, such as a metal halide perovskite passivated with an organic dye. The electronic devices may include solar cells. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/684991 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/0036 (20130101) H01G 9/2009 (20130101) Original (OR) Class Organic electric solid-state devices H10K 30/88 (20230201) H10K 85/30 (20230201) H10K 85/655 (20230201) H10K 85/657 (20230201) H10K 85/6572 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040531 | Keller, III |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NOKOMIS, INC. (Charleroi, Pennsylvania) |
| ASSIGNEE(S) | NOKOMIS, INC. (Canonsburg, Pennsylvania) |
| INVENTOR(S) | Walter J. Keller, III (Bridgeville, Pennsylvania) |
| ABSTRACT | A diagnostic apparatus for analysis, testing, inspecting and/or screening an integrated and assembled electrically powered equipment rack and its populated cards and devices for measurement of degree of device aging, improper operation, degradation, condition, and/or Remaining Useful Life (RUL). The device includes an antenna card with a detachably attachable antenna module that can be positioned at a distance from the electrically devices under test and a signal receiver or sensor for examining a signal from the electrically powered device, but especially applied to rackmount supported electronics and/or chassis based electronics. The receiver or sensor collects unintended and/or intended RF energy components emitted by the electrically powered device and performs the above analysis in a response to the acquired signal input while the electrically powered device is active or powered. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/355847 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/002 (20130101) Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 1/247 (20130101) H01Q 1/2275 (20130101) Original (OR) Class H01Q 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040558 | Lialios et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dimitrios Lialios (Miami, Florida); Constantinos Zekios (Miami, Florida); Stavros Georgakopoulos (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Dimitrios Lialios (Miami, Florida); Constantinos Zekios (Miami, Florida); Stavros Georgakopoulos (Miami, Florida) |
| ABSTRACT | Ultrawideband (UWB) beamforming networks are provided. A UWB beamforming network can have azimuth angle scanning and elevation angle scanning. A modified version of the Blass matrix topology can be used to achieve two-dimensional (2D) scanning behavior. The beamforming network can simultaneously excite a plurality of beams, and each of these beams can be at any chosen frequency inside the bandwidth that the beamformer covers. Each beam can be designed to point at any arbitrary direction, which can be defined by the desired elevation angle and azimuth angle, in the 2D plane. |
| FILED | Friday, June 02, 2023 |
| APPL NO | 18/328382 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/26 (20130101) H01Q 3/30 (20130101) H01Q 3/34 (20130101) H01Q 3/40 (20130101) Original (OR) Class H01Q 3/2682 (20130101) H01Q 21/0006 (20130101) H01Q 21/0025 (20130101) H01Q 21/061 (20130101) H01Q 21/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12037258 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Jie Li (Darien, Illinois); Mai Kim Tran (Orlando, Florida); Ralph T. Muehleisen (Oak Park, Illinois) |
| ABSTRACT | The invention provides a method for continuously producing composite nanoparticles, the method comprising heating a precursor mixture with supercritical water, wherein the mixture contains a first compound capable of transitioning from a monoclinic to a tetragonal rutile crystal state; cooling the heated mixture to obtain core particles of a predetermined shape and size; encapsulating the core particle with a second precursor to create a core-shell construct; and encapsulating the construct with an organic material. Also provided is a device for continuously synthesizing composite nanoparticles, the device comprising a water supply and a precursor supply; a means for heating the water, a continuous flow hydrothermal reaction chamber adapted to receive the heated water and precursor, a means for chilling the heated water and precursor, and a capping agent supply positioned downstream of the reaction chamber. The invention also provides a nanocomposite particle comprising a core region, and a conformal organic overcoat. |
| FILED | Tuesday, February 02, 2021 |
| APPL NO | 17/165587 |
| ART UNIT | 1759 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00033 (20130101) B01J 2219/00051 (20130101) B01J 2219/00162 (20130101) B01J 2219/00166 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 31/02 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2004/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037555 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Kunlei Liu (Lexington, Kentucky); Heather Nikolic (Stamping Ground, Kentucky) |
| ABSTRACT | A biomass fuel slurry includes a mixture of a biomass material and a plastic material suspended in water. In other embodiments, the biomass fuel slurry also includes coal. A method of making a biomass fuel slurry includes the steps of encapsulating a biomass material with a plastic material to produce a plastic encapsulated biomass material and suspending the plastic encapsulated biomass material in water. |
| FILED | Tuesday, August 02, 2022 |
| APPL NO | 17/879370 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/328 (20130101) Original (OR) Class C10L 2200/0461 (20130101) C10L 2200/0469 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037592 | Loque et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Dominique Loque (Vernier, Switzerland); Aymerick Guillaume Eudes (Emeryville, California); Patrick M. Shih (Berkeley, California) |
| ABSTRACT | The present invention provides for a genetically modified plant or plant cell comprising a nucleic acid encoding one or more heterologous enzymes operatively linked a promoter, wherein one or more heterologous enzymes synthesizes muconic acid (MA). |
| FILED | Thursday, February 20, 2020 |
| APPL NO | 16/796790 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8243 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037945 | Sobanski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Jon E. Sobanski (Glastonbury, Connecticut); Jacob C. Snyder (East Haddam, Connecticut) |
| ABSTRACT | A powerplant for an aircraft includes a turbine engine core, a recovery system and a flowpath. The turbine engine core includes a compressor section, a combustor section and a turbine section. The recovery system includes a condenser and a flow circuit. The flow circuit includes a separator and a treatment device. The recovery system is configured to condense water flowing within the flowpath from a gaseous phase to a liquid phase using the condenser. The recovery system is configured to direct the water in the liquid phase from the flowpath into the flow circuit using the separator. The recovery system is configured to treat a quantity of the water within the flow circuit using the treatment device to provide treated water. The recovery system is configured to provide a quantity of the treated water to the turbine engine core. |
| FILED | Friday, June 23, 2023 |
| APPL NO | 18/213654 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/30 (20130101) F02C 7/22 (20130101) F02C 7/141 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2260/609 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12037996 | Momen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Ayyoub Mehdizadeh Momen (Knoxville, Tennessee); Ahmed Abuheiba (Knoxville, Tennessee); Saiid Kassaee (Knoxville, Tennessee) |
| ABSTRACT | A gas compressor system includes a compression liquid holding tank in fluid communication with a combustion tank. A combustible fluid is directed to the combustion tank. An ignition system is provided for igniting the combustible fluid. A compression liquid flows between the liquid holding tank, the combustion tank, and a compression tank. A compressible gas is provided in the compression tank. The ignition of the combustible fluid drives the compression liquid from the combustion tank to the compression tank, compressing the compressible liquid. An HVAC&R system and a method of compressing gas are also disclosed. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/396968 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Positive-displacement Machines for Liquids; Pumps F04B 23/02 (20130101) F04B 23/08 (20130101) F04B 35/008 (20130101) F04B 39/0011 (20130101) F04B 41/02 (20130101) Original (OR) Class Pumping of Fluid by Direct Contact of Another Fluid or by Using Inertia of Fluid to be Pumped; Siphons F04F 1/16 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 31/00 (20130101) F25B 31/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038242 | Glass, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Samuel W. Glass, III (Richland, Washington); Morris S. Good (Pasco, Washington); Matthew S. Prowant (Richland, Washington) |
| ABSTRACT | Heat exchanger assemblies are provided that can include: a heat exchanger housing; at least one primary conduit operably coupled to the heat exchanger housing and configured to convey a primary heat exchange fluid; at least one secondary conduit operably coupled to the heat exchanger housing and configured to convey a secondary heat exchange fluid; at least one thermal interface between the primary and secondary fluids; and at least one sensor operably engaged with the thermal interface. Heat exchanger assemblies including molten salt, liquid metal, or water/steam as part of the heat exchange fluids of the heat exchanger assembly are provided. The heat exchanger assemblies can include: at least one thermal interface between primary and secondary heat exchange fluids of the heat exchanger assembly; and a sensor operably engaged with the at least one interface. |
| FILED | Monday, June 08, 2020 |
| APPL NO | 16/895661 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 27/00 (20130101) Original (OR) Class F28F 2265/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/041 (20130101) G01N 29/223 (20130101) G01N 29/2475 (20130101) Nuclear Reactors G21C 17/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038285 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jongmin Lee (Albuquerque, New Mexico); Daniel Beom Soo Soh (Pleasanton, California) |
| ABSTRACT | A hybrid inertial navigation system and method are provided. The system includes a conventional inertial measurement unit (with a three-axis accelerometer and a three-axis gyroscope operating at a high data rate and low sensitivity), light pulse atom interferometer accelerometer and gyroscope (operating at a low data rate and high sensitivity), and a processing system. The method of the hybrid inertial navigation system includes precisely determining an acceleration and an angular velocity and allowing light pulse atom interferometry operation under dynamic environments. A processing system of the hybrid inertial navigation system performs feedforward correction operations on the light-pulse atom interferometer accelerometer and gyroscope of the hybrid inertial navigation system. The processing system determines one or more control signals based on the inertial information from the conventional inertial measurement unit, a light pulse atom interferometer model, and the feedforward algorithm. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/396902 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/18 (20130101) Original (OR) Class G01C 21/1656 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038333 | Cetiner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Nesrin O. Cetiner (Oak Ridge, Tennessee); Mustafa S. Cetiner (Oak Ridge, Tennessee); Michael J. Roberts (Oak Ridge, Tennessee); Thomas R. Muth (Oak Ridge, Tennessee); Venugopal K. Varma (Oak Ridge, Tennessee); Rosemary A. Montgomery (Oak Ridge, Tennessee); Govindarajan Muralidharan (Oak Ridge, Tennessee) |
| ABSTRACT | An improved ultrasonic waveguide for an ultrasonic thermometry system is provided. The waveguide includes a series of sensing zones, each of which is tuned to a specific narrow frequency band. The waveguide is acoustically coupled to a transducer, which launches a longitudinal elastic wave of desired waveform and frequency. The wave propagates down the waveguide, and is reflected from the sensing zone that is tuned to that frequency. Each sensing zone is designed to be highly reflective to a narrow frequency band while being transparent to other frequencies. |
| FILED | Friday, August 21, 2020 |
| APPL NO | 16/999205 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 11/24 (20130101) Original (OR) Class G01K 11/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/228 (20130101) G01N 2291/02881 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038416 | Nation et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Brendan L. Nation (Albuquerque, New Mexico); Michael T. Dugger (Tijeras, New Mexico); John Curry (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates, in part, to systems for characterizing force (e.g., friction, and wear). In one embodiment, a tribometer allows for wear testing of samples in a high throughput manner. A counterface is used to apply force on the surface of the sample. A carousel provides for the rapid exchange of new for old counterfaces in the tribometer test head, thereby enabling the use of a new counterface for each new wear test without the need for operator interaction. |
| FILED | Monday, November 01, 2021 |
| APPL NO | 17/515815 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/04 (20130101) G01N 3/56 (20130101) Original (OR) Class G01N 3/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038507 | Bagwell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Brett Bagwell (Albuquerque, New Mexico) |
| ABSTRACT | Various technologies pertaining to optical measurement of cross-wind are described herein. A beam of light is emitted along a trajectory through a shooting space from a location of a shooter to a target using a laser. The beam is reflected by the target, and the beam is received at two optical detectors. Due to changes in the index of refraction of air along the path of the beam, an envelope signal atmospherically encoded on the beam is received at each of the two apertures at different times. A signal analyzer receives a signal from each of the detectors and outputs data indicative of an average speed of the cross-wind along the trajectory in the shooting space based upon a time delay between the signals. |
| FILED | Wednesday, August 02, 2017 |
| APPL NO | 15/667516 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038553 | Labov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Simon E. Labov (Berkeley, California); Karl E. Nelson (Livermore, California); Brandon S. Seilhan (Emeryville, California) |
| ABSTRACT | A system identifying a source of radiation is provided. The system includes a radiation source detector and a radiation source identifier. The radiation source detector receives measurements of radiation; for one or more sources, generates a detection metric indicating whether that source is present in the measurements; and evaluates the detection metrics to detect whether a source is present in the measurements. When the presence of a source in the measurements is detected, the radiation source identifier for one or more sources, generates an identification metric indicating whether that source is present in the measurements; generates a null-hypothesis metric indicating whether no source is present in the measurements; evaluates the one or more identification metrics and the null-hypothesis metric to identify the source, if any, that is present in the measurements. |
| FILED | Tuesday, October 25, 2022 |
| APPL NO | 17/972761 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/36 (20130101) G01T 1/167 (20130101) Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/26 (20240101) Original (OR) Class G01V 5/281 (20240101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039201 | Brewer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas); Michael Keith Dugan (Richardson, Texas) |
| ABSTRACT | Host and accelerator devices can be coupled using various interfaces, such as Compute Express Link (CXL). In an example, user applications can have protected access to a shared set of control parameters for different queues. A protocol can allow an application to use a unique memory page at the accelerator device through which the application can access control parameters, such as can be used to control memory-based communication queues or other queues. In an example, there can be multiple sets of control parameters in a single memory page. The protocol can allow views of the single memory page from respective different application processes. In an example, the protocol can include or use an access check to detect and handle unauthorized accesses to particular parameters. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/898803 |
| ART UNIT | 2138 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0622 (20130101) G06F 3/0659 (20130101) Original (OR) Class G06F 3/0679 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039226 | Branch |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Darren W. Branch (Albuquerque, New Mexico) |
| ABSTRACT | A method for detecting a change in an environment is disclosed. The method includes forming a test acoustic signal based on time-reversal of a baseline acoustic signal after the baseline acoustic signal has traversed the environment while the environment is in a baseline condition. The method also includes detecting the test acoustic signal after the test acoustic signal has traversed the environment while the environment is in an unknown condition. The method includes determining whether there has been a change in the environment by comparing the baseline acoustic signal with the detected test acoustic signal after the test acoustic signal has traversed the environment while the environment is in the unknown condition. |
| FILED | Wednesday, May 11, 2022 |
| APPL NO | 17/741629 |
| ART UNIT | 2691 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/165 (20130101) Original (OR) Class Stereophonic Systems H04S 7/301 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039676 | Horak et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Karl Emanuel Horak (Albuquerque, New Mexico); Deborah Ann Haycraft (Albuquerque, New Mexico); Heidi A. Smartt (Albuquerque, New Mexico) |
| ABSTRACT | A system and method for visual alignment of Reflective Particle Tags (RPT) includes creating a three-dimensional digital model of a reticle; processing a plurality of features based on the digital model; generating an Augmented Reality application; and deploying the Augmented Reality application on a camera platform. The augmented reality alignment system includes processors and memory devices having instructions that, when executed by the processors, cause the processors to perform operations of creating a three-dimensional digital model of a reticle; processing a plurality of features based on the digital model; generating an Augmented Reality application; and deploying the Augmented Reality application on a camera platform. A non-transitory, computer-readable medium comprising instructions that, cause the processors to create a model of a reticle; process features based on the model; generate an Augmented Reality application; and deploy the application on a camera. |
| FILED | Wednesday, April 27, 2022 |
| APPL NO | 17/730491 |
| ART UNIT | 2617 — Optics |
| CURRENT CPC | Card, Board, or Roulette Games; Indoor Games Using Small Moving Playing Bodies; Video Games; Games Not Otherwise Provided for A63F 13/52 (20140902) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/0723 (20130101) G06K 19/06028 (20130101) G06K 19/06037 (20130101) Image Data Processing or Generation, in General G06T 17/00 (20130101) G06T 19/006 (20130101) Original (OR) Class G06T 19/20 (20130101) G06T 2219/2004 (20130101) Pictorial Communication, e.g Television H04N 23/635 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040053 | Vuyisich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BlueDot LLC (Bellevue, Washington); TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | BLUEDOT, LLC (Bellevue, Washington); TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Momchilo Vuyisich (Los Alamos, New Mexico); Jason Gans (Los Alamos, New Mexico); Patrick Chain (Los Alamos, New Mexico); Andrew Hatch (Los Alamos, New Mexico) |
| ABSTRACT | Provided herein are compositions and methods for analyzing nucleic acids in a sample. Compositions include simple barcode sets having reduced DNA sequencing instrument-specific error rates. Methods include methods to deconvolute sequence reads from different samples. |
| FILED | Thursday, June 21, 2018 |
| APPL NO | 16/621998 |
| ART UNIT | 1671 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 2537/165 (20130101) C12Q 2563/179 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 25/20 (20190201) G16B 35/10 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040102 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Michael A. Brown (Chicago, Illinois); David J. Bettinardi (Chicago, Illinois); Peter Tkac (Naperville, Illinois) |
| ABSTRACT | A method for separating a parent isotope from a daughter isotope is provided, the method comprising supplying irradiated target; dissolving the irradiated target; treating the dissolved irradiated target to a precipitation step to form a first solid phase of the parent isotope and a first liquid phase of the daughter isotope; filtering the first liquid phase of daughter isotope to create a first purified fraction of the daughter isotope to create a second solid phase of the parent isotope and a second liquid phase of the daughter isotope; and filtering the second liquid phase to create a second liquid fraction of the daughter isotope. The process can be repeated until the 99Mo is exhausted and the enriched target material 98Mo or 100Mo can be easily re-used. |
| FILED | Thursday, April 16, 2020 |
| APPL NO | 16/850783 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Conversion of Chemical Elements; Radioactive Sources G21G 1/001 (20130101) Original (OR) Class G21G 2001/0042 (20130101) G21G 2001/0073 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
12040477 — 3-D composite anodes for Li-ion batteries with high capacity and fast charging capability
| US 12040477 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Kuan-Hung Chen (Ann Arbor, Michigan); Neil Dasgupta (Ann Arbor, Michigan); Jeffrey Sakamoto (Ann Arbor, Michigan); Min Ji Namkoong (Ann Arbor, Michigan) |
| ABSTRACT | A lithium-ion battery includes an electrode with a plurality of channels formed at least partially through its thickness. Each channel has a diameter in a range from 5 μm to 100 μm and/or is spaced apart from another channel by a distance in a range from 10 μm to 200 μm as measured between centerlines of the channels. The electrode may be an anode and includes carbonaceous material such as graphite and/or additional electrochemically active lithium host materials. The battery can be charged at a C-rate greater than 2 C. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/121525 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 50/46 (20210101) H01M 2004/021 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040506 | Carlson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LG Energy Solution, Ltd. (Seoul, South Korea) |
| ASSIGNEE(S) | LG Energy Solution, Ltd. (Seoul, South Korea) |
| INVENTOR(S) | Steven A. Carlson (Cambridge, Massachusetts); Benjamin Sloan (Exeter, New Hampshire); David W. Avison (Boxborough, Massachusetts) |
| ABSTRACT | Provided is a lithium battery, wherein the battery comprises an anode, a cathode, wherein the cathode comprises one or more transition metals, an electrolyte, and a porous separator interposed between the cathode and anode, wherein the separator comprises an anionic compound. Also provided are methods of manufacturing such batteries. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 17/831964 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/20 (20130101) H01G 11/50 (20130101) H01G 11/52 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 10/052 (20130101) H01M 10/0525 (20130101) H01M 10/0585 (20130101) H01M 50/46 (20210101) H01M 50/446 (20210101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040677 | Bird |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Portland State University (Portland, Oregon) |
| ASSIGNEE(S) | Portland State University (Portland, Oregon) |
| INVENTOR(S) | Jonathan Bird (Portland, Oregon) |
| ABSTRACT | The disclosure presents configurations and analyses of magnetic gears, which may be used in the second stage of a multistage magnetically geared generator for a marine hydrokinetic generator application and/or other applications as described. In order to reduce field harmonics and maximize the torque density, a Halbach rotor topology is utilized. One feature of the disclosed configuration is a unique magnet arrangement that enables inner and outer Halbach rotor magnets to be more easily assembled, even with dimensional tolerance inaccuracies. The disclosed Halbach magnet rotor topology makes use of the internal magnet forces to retain the magnets in position, and the disclosed configuration also helps with the assembly process. |
| FILED | Monday, September 28, 2020 |
| APPL NO | 17/035471 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 49/102 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040696 | Mazumder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Sudip K. Mazumder (Chicago, Illinois); Moien Mohamadi (Sanandaj, Iran); Nikhil Kumar (New Delhi, India) |
| ABSTRACT | A system for charging a battery includes three sub-modules, each receiving a respective phase of a three-phase alternating current (AC) signal. The three sub-modules cooperate to transform the respective phases of the three-phase AC signal to a direct current (DC) signal by passing the respective phases of the three-phase AC signal through a respective semiconductor device configured to discontinuously modulate the respective phase of the three-phase AC signal to convert it to a DC signal provided to the battery to charge the battery. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 17/984773 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/32 (20130101) Original (OR) Class H02M 1/4216 (20130101) H02M 3/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12037126 | Ilic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SmartGridz, Inc. (Sudbury, Massachusetts) |
| ASSIGNEE(S) | SmartGridz, Inc. (Sudbury, Massachusetts) |
| INVENTOR(S) | Marija Ilic (Sudbury, Massachusetts); Rupamathi Jaddivada (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed herein is a fundamental modeling and control method in dynamic energy conversion and transfers in complex energy systems with multiple energy sources, fuel and electric. The multi-layered modeling enables efficient and stable operation through optimized coordination of engines and electric part of a hybrid turbo-electric distribution system (TeDP). A provable coordination of power and rate of change of power interactions between the components is done at the higher-system level. Advanced nonlinear control of components is disclosed to ensure that components meet power/rate of change of power commands given by the higher level. This method is used to demonstrate, for the first time, how rotor stall and surge instabilities in engines can be eliminated by controlling the electric generators and/or storage. |
| FILED | Thursday, September 12, 2019 |
| APPL NO | 16/568904 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/02 (20130101) B64D 27/10 (20130101) B64D 27/24 (20130101) B64D 31/06 (20130101) Original (OR) Class B64D 2027/026 (20130101) B64D 2221/00 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 9/48 (20130101) Electric Digital Data Processing G06F 30/13 (20200101) G06F 30/15 (20200101) G06F 30/17 (20200101) G06F 30/20 (20200101) G06F 2119/02 (20200101) G06F 2119/06 (20200101) G06F 2119/14 (20200101) G06F 2119/16 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038600 | Leifer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Stephanie D. Leifer (Pasadena, California); Wei Zhang (Pasadena, California); Andrey B. Matsko (Arcadia, California) |
| ABSTRACT | Disclosed herein is a pulse repetition rate multiplier including a photonic integrated circuit (PIC) including cascading Mach-Zehnder interferometers (MZIs). An input may be connected to one end of the PIC and an output may be connected to the other end of the PIC such that a signal from the input runs through the cascading MZIs and out the output. The input may be configured to receive an input pulsed signal and the output may be configured to output a repetition rate multiplied signal. Advantageously, using a PIC as opposed to an optical fiber-based pulse rate multiplier allows for accurate fabrication of a pulse repetition rate multiplier configured to accept higher frequency pulsed signals. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 17/643974 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) G02B 6/12007 (20130101) Original (OR) Class G02B 2006/1215 (20130101) G02B 2006/12061 (20130101) G02B 2006/12147 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/212 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040099 | Shargots et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BWXT Nuclear Energy, Inc. (Lynchburg, Virginia) |
| ASSIGNEE(S) | BWXT Nuclear Energy, Inc. (Lynchburg, Virginia) |
| INVENTOR(S) | Scott J. Shargots (Forest, Virginia); Scott Lee Fitzner (Appomattox, Virginia); Emily Fleming (Forest, Virginia); Ryan Z. Ziegler (Forest, Virginia); Todd Oswald (Charlotte, North Carolina); Earl Brian Barger (Goode, Virginia) |
| ABSTRACT | A nuclear fuel assembly for a nuclear reactor core, the fuel assembly having at least one fuel element including an elongated shell defining an interior volume, a lattice structure disposed within the interior volume, at least one flow channel extending through the lattice structure, at least one lattice site disposed in the lattice structure, and at least one fuel compact disposed within a corresponding one of the at least one lattice site, a first end cap including a boss having a first cross-sectional shape, the first end cap being affixed to a first end of the shell, and a second end cap including a first bore having a second cross-sectional shape, the second end cap being affixed to a second end of the shell, wherein the first cross-sectional shape of the boss is the same as the cross-sectional shape of the bore. |
| FILED | Friday, May 28, 2021 |
| APPL NO | 17/334060 |
| ART UNIT | 3619 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Nuclear Reactors G21C 3/33 (20130101) Original (OR) Class G21C 3/322 (20130101) G21C 5/02 (20130101) Nuclear Power Plant G21D 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040586 | Refaat et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Tamer F. Refaat (Hampton, Virginia); Mulugeta Petros (Newport News, Virginia); Upendra N. Singh (Yorktown, Virginia) |
| ABSTRACT | A dynamic, thermally-adaptive cuboid laser crystal mount is provided that is suitable for use with end-pumped, conductively-cooled solid state lasers. Various embodiments may provide a mount for supporting a cuboid rod host crystal for an end-pumping solid state laser. Various embodiments may solve laser crystal stress problems typically experienced in end-pumped solid state lasers. Various embodiments may also provide access to the crystal end surfaces for pumping and enable and maintain sturdy alignment of the crystal with continuous and uniform surface contact between the mount and the crystal. Various embodiments of mounts may provide a compact conductive cooling configuration compatible with any heat sink reservoir, controlling and maintaining a stable crystal temperature, thus avoiding thermally induced mechanical stresses. Various embodiment mounts may thereby further extend the fracture threshold of the laser crystal. |
| FILED | Wednesday, February 19, 2020 |
| APPL NO | 16/794522 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/025 (20130101) H01S 3/042 (20130101) Original (OR) Class H01S 3/0405 (20130101) H01S 3/0602 (20130101) H01S 3/0606 (20130101) H01S 3/0612 (20130101) H01S 3/08072 (20130101) H01S 3/09415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040836 | Divsalar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Dariush Divsalar (Pasadena, California); William H Farr (Pasadena, California); Makan Mohageg (Pasadena, California); Samuel J Dolinar (Pasadena, California); Matthew D Thill (Pasadena, California) |
| ABSTRACT | Methods and devices implementing a combination of multi-dimensional pulse position modulation (PPM) with wavelength division multiplexing (WDM) or wavelength division multiplexing multiple access (WDMA) for long range space communications are disclosed. The described multi-dimensional PPM scheme can use the laser wavelength and/or polarization as the additional dimension(s) to the time dimension. Through examples it is shown that the disclosed teachings result in a higher photon information efficiency. Various exemplary embodiments are also presented to highlight the applications benefiting from the disclosed methods and devices. |
| FILED | Friday, May 26, 2023 |
| APPL NO | 18/324433 |
| ART UNIT | 2634 — Digital Communications |
| CURRENT CPC | Transmission H04B 10/54 (20130101) H04B 10/503 (20130101) Original (OR) Class Multiplex Communication H04J 14/005 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/4902 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12041468 | Barsoum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Constellation Designs, LLC (Wayne, Pennsylvania) |
| ASSIGNEE(S) | Constellation Designs, LLC (Wayne, Pennsylvania) |
| INVENTOR(S) | Maged F. Barsoum (San Jose, California); Christopher R. Jones (Pacific Palisades, California) |
| ABSTRACT | Communication systems are described that use signal constellations, which have unequally spaced (i.e. ‘geometrically’ shaped) points. In many embodiments, the communication systems use specific geometric constellations that are capacity optimized at a specific SNR, over the Rayleigh fading channel. In addition, ranges within which the constellation points of a capacity optimized constellation can be perturbed and are still likely to achieve a given percentage of the optimal capacity increase compared to a constellation that maximizes dmin, are also described. Capacity measures that are used in the selection of the location of constellation points include, but are not limited to, parallel decode (PD) capacity and joint capacity. |
| FILED | Friday, June 11, 2021 |
| APPL NO | 17/346153 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 5/006 (20130101) H04L 27/3405 (20130101) Wireless Communication Networks H04W 24/02 (20130101) Original (OR) Class H04W 72/0453 (20130101) H04W 72/0473 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 12035971 | Abramoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | University of lowa Research Foundation (Iowa City, Iowa); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Michael D. Abramoff (University Heights, Iowa); Meindert Niemeijer (Iowa City, Iowa); Xiayu Xu (Iowa City, Iowa); Milan Sonka (Coralville, Iowa); Joseph M. Reinhardt (Iowa City, Iowa) |
| ABSTRACT | The methods and systems provided can automatically determine an Arteriolar-to-Venular diameter Ratio, AVR, in blood vessels, such as retinal blood vessels and other blood vessels in vertebrates. The AVR is an important predictor of increases in the risk for stroke, cerebral atrophy, cognitive decline, and myocardial infarct. |
| FILED | Friday, March 17, 2023 |
| APPL NO | 18/185704 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) Original (OR) Class A61B 3/0016 (20130101) A61B 3/0058 (20130101) A61B 3/1225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036042 | Majerus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); THE UNITED STATES AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Steve J A Majerus (University Heights, Ohio); Jeremy Dunning (Cleveland Heights, Ohio); Katherine M. Bogie (Cleveland, Ohio); Joseph A. Potkay (Plymouth, Michigan) |
| ABSTRACT | A sensor apparatus includes at least one substrate layer of an elastically deformable material, the substrate layer extending longitudinally between spaced apart ends thereof. A conductive layer is attached to and extends longitudinally between the spaced apart ends of the at least one substrate layer. The conductive layer includes an electrically conductive material adapted to form a strain gauge having an electrical resistance that varies based on deformation of the conductive layer in at least one direction. |
| FILED | Monday, February 13, 2023 |
| APPL NO | 18/108808 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/026 (20130101) A61B 5/683 (20130101) Original (OR) Class A61B 5/02141 (20130101) A61B 5/02444 (20130101) A61B 5/6876 (20130101) A61B 2562/12 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/06 (20130101) G01L 9/0052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036255 | Maresso et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas); The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Anthony Maresso (Houston, Texas); Robert Ramig (Houston, Texas); Sabrina Green (Houston, Texas); Austen Terwilliger (Houston, Texas); Keiko Salazar (Houston, Texas); Justin R. Clark (Houston, Texas); Barbara Trautner (Houston, Texas) |
| ABSTRACT | Disclosed are compositions, devices, kits, and methods for treatment of Enterobacteriaceae infection. Aspects of the present disclosure are directed to bacteriophage compositions comprising one or more of ES17, ES19, HP3, HP3.1, and HP3.2. Certain aspects of the disclosure are directed to compositions comprising (a) bacteriophage ES17 or bacteriophage ES19, (b) bacteriophage HP3, and (c) bacteriophage HP3.1. Also disclosed are compositions comprising bacteriophage HP 3.2. Further disclosed are devices and kits comprising such compositions and methods for use of such compositions in treatment and prevention of pathogenic E. coli infection. |
| FILED | Monday, January 09, 2023 |
| APPL NO | 18/152077 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2795/10132 (20130101) C12N 2795/10171 (20130101) C12N 2795/10232 (20130101) C12N 2795/10271 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036314 | Myung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The U.S. Government Represented by the Department of Veterans Affairs (NW Washington, District of Columbia) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | David Myung (Stanford, California); Sarah Hull (Stanford, California); Sarah Heilshorn (Mountain View, California); Christopher Lindsay (San Mateo, California); Christopher Madl (Los Altos, California); Hyun Jong Lee (Gyeonggi-do, South Korea) |
| ABSTRACT | Compositions and methods are provided for lamellar and defect reconstruction of corneal stromal tissue using biomaterials that form a defined gel structure in situ. Such gels can serve as cellular or acellular lamellar substitutes to reconstruct corneal stroma, facilitate matrix remodeling, and support multilayered re-epithelialization of wounded corneal stromal tissue, as well delivery vehicles for cells, biomolecules, and/or pharmaceutical agents to wound sites throughout the body. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 17/251605 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/142 (20130101) A61F 2210/0076 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0051 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/36 (20130101) A61K 47/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 12036078 | Weitekamp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | POLYSPECTRA, INC. (Berkeley, California) |
| ASSIGNEE(S) | POLYSPECTRA, INC. (Berkeley, California) |
| INVENTOR(S) | Raymond A. Weitekamp (Berkeley, California); Aditya Balasubramanian (Berkeley, California) |
| ABSTRACT | The present disclosure relates to a method for generating a dental product or an orthodontic product. The method may comprise (a) providing a mixture comprising (i) a latent ruthenium (Ru) complex; (ii) an initiator; (iii) a sensitizer that sensitizes said initiator; and (iv) at least one polymer precursor; and (b) exposing the mixture to electromagnetic radiation to activate the initiator, wherein upon activation, the initiator reacts with the latent Ru complex to generate an activated Ru complex, which activated Ru complex reacts with the at least one polymer precursor to generate at least a portion of a final product of the dental product or the orthodontic product, wherein the at least the portion of the final product of the dental product or the orthodontic product comprises a polymer generated from the at least one polymer precursor. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 17/399368 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Dentistry; Apparatus or Methods for Oral or Dental Hygiene A61C 13/0013 (20130101) Original (OR) Class A61C 13/0019 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 6/62 (20200101) A61K 6/887 (20200101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/35 (20170801) B29C 64/124 (20170801) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/753 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 2261/418 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12036264 | Cadete Pires et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NovoBiotic Pharmaceuticals, LLC (Cambridge, Massachusetts) |
| ASSIGNEE(S) | NovoBiotic Pharmaceuticals, LLC (Cambridge, Massachusetts) |
| INVENTOR(S) | Ana Cristina Cadete Pires (Cambridge, Massachusetts); Aranda Rae Duan (Medford, Massachusetts); Losee Lucy Ling (Arlington, Massachusetts) |
| ABSTRACT | The present invention provides pharmaceutical compositions of teixobactin that are capable of preventing gelation of teixobactin. The pharmaceutical compositions comprise teixobactin and a pegylated phospholipid. The present invention also provides methods of preparing the pharmaceutical compositions of teixobactin and methods of treating a subject using the pharmaceutical compositions of teixobactin. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/969598 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/15 (20130101) Original (OR) Class A61K 47/24 (20130101) A61K 47/26 (20130101) A61K 47/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12039765 | Buckler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| INVENTOR(S) | Andrew J. Buckler (Boston, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts); Mark A. Buckler (Wenham, Massachusetts); Vladimir Valtchinov (Boston, Massachusetts); David S. Paik (Moon Bay, California) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Monday, May 01, 2023 |
| APPL NO | 18/309903 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/24 (20230101) G06F 18/211 (20230101) G06F 18/2148 (20230101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 3/00 (20130101) G06T 5/73 (20240101) G06T 7/11 (20170101) G06T 7/0012 (20130101) G06T 2207/10048 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10101 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/30096 (20130101) G06T 2207/30104 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) Original (OR) Class G06V 10/764 (20220101) G06V 20/69 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12040531 | Keller, III |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NOKOMIS, INC. (Charleroi, Pennsylvania) |
| ASSIGNEE(S) | NOKOMIS, INC. (Canonsburg, Pennsylvania) |
| INVENTOR(S) | Walter J. Keller, III (Bridgeville, Pennsylvania) |
| ABSTRACT | A diagnostic apparatus for analysis, testing, inspecting and/or screening an integrated and assembled electrically powered equipment rack and its populated cards and devices for measurement of degree of device aging, improper operation, degradation, condition, and/or Remaining Useful Life (RUL). The device includes an antenna card with a detachably attachable antenna module that can be positioned at a distance from the electrically devices under test and a signal receiver or sensor for examining a signal from the electrically powered device, but especially applied to rackmount supported electronics and/or chassis based electronics. The receiver or sensor collects unintended and/or intended RF energy components emitted by the electrically powered device and performs the above analysis in a response to the acquired signal input while the electrically powered device is active or powered. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/355847 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/002 (20130101) Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 1/247 (20130101) H01Q 1/2275 (20130101) Original (OR) Class H01Q 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 12035720 | Roeder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey F. Roeder (Brookfield, Connecticut); Melissa A. Petruska (Newtown, Connecticut); Trevor E. James (Plantsville, Connecticut); Thomas J. Spoonmore (Norwalk, Connecticut); Peter C. Van Buskirk (Newtown, Connecticut) |
| ASSIGNEE(S) | Sonata Scientific LLC (Danbury, Connecticut) |
| INVENTOR(S) | Jeffrey F. Roeder (Brookfield, Connecticut); Melissa A. Petruska (Newtown, Connecticut); Trevor E. James (Plantsville, Connecticut); Thomas J. Spoonmore (Norwalk, Connecticut); Peter C. Van Buskirk (Newtown, Connecticut) |
| ABSTRACT | Polymer coatings and surfaces are disclosed with antimicrobial properties. The antimicrobial action is provided by high surface area materials contained within the coating or surface. The high surface area materials may contain photocatalysts that create reactive oxygen species upon exposure to visible light or transition metals that create reactive oxygen species upon exposure to hydrogen peroxide. The high surface area materials may also sorb disinfecting liquids and desorb them over time to provide disinfection. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/343723 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/10 (20130101) A01N 59/06 (20130101) A01N 59/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038408 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Xudong Fan (Saline, Michigan); Hongbo Zhu (Johnson City, Tennessee); Katsuo Kurabayashi (Ann Arbor, Michigan) |
| ABSTRACT | An integrated microfluidic photoionization detector (PID) is provided including a microfluidic ionization chamber a microfluidic ultraviolet radiation chamber that is configured to generate ultraviolet photons. An ultrathin transmissive window is disposed between the microfluidic ionization chamber and the microfluidic ultraviolet radiation chamber that permits the ultraviolet photons to pass from the microfluidic ultraviolet radiation chamber into the microfluidic ionization chamber. Detection systems for one or more VOC analytes are also provided that include a gas chromatography (GC) unit including at least one gas chromatography column and an integrated microfluidic photoionization detector (PID) disposed downstream of the gas chromatography (GC) unit. |
| FILED | Wednesday, October 02, 2019 |
| APPL NO | 17/282671 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/64 (20130101) Original (OR) Class G01N 30/64 (20130101) G01N 30/463 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 12036003 | Aronoff-Spencer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eliah Aronoff-Spencer (San Diego, California); Tom Kalisky (La Jolla, California); Daniel Johnson (Escondido, California); Alex Grant (San Diego, California); Steve Saggese (San Diego, California) |
| ABSTRACT | A multimodal biometric device is disclosed. An apparatus may include a non-contact imaging system. The non-contact imaging system may include imaging optics, optical illumination optically coupled to the imaging optics, and a configurable body part support to support different body parts at corresponding focal lengths to capture different portions of the different body parts. An apparatus may also include a housing coupled to the imaging optics, the optical illumination, and the configurable body part support. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 17/416319 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) Original (OR) Class A61B 5/0033 (20130101) Image or Video Recognition or Understanding G06V 10/143 (20220101) G06V 10/147 (20220101) G06V 40/15 (20220101) G06V 40/45 (20220101) G06V 40/70 (20220101) G06V 40/1312 (20220101) G06V 40/1347 (20220101) G06V 40/1382 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Nuclear Regulatory Commission (NRC)
| US 12036695 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Jung-Kun Lee (Sewickley Hills, Pennsylvania); Ian Nettleship (Pittsburgh, Pennsylvania); Ryan W. Read (Indiana, Pennsylvania) |
| ABSTRACT | A bonding tape for joining carbide ceramic structures, wherein the bonding tape comprises: a mixture comprising carbide ceramic particles, preceramic polymer liquid, fine carbon particles and metal nanoparticles that form a eutectic liquid at temperatures below 1400° C. |
| FILED | Monday, February 01, 2021 |
| APPL NO | 17/164474 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/64 (20130101) C04B 35/565 (20130101) C04B 35/571 (20130101) C04B 35/632 (20130101) C04B 35/5607 (20130101) C04B 35/5626 (20130101) C04B 37/005 (20130101) C04B 2235/40 (20130101) C04B 2235/80 (20130101) C04B 2235/405 (20130101) C04B 2235/422 (20130101) C04B 2235/483 (20130101) C04B 2235/5454 (20130101) C04B 2235/6025 (20130101) C04B 2237/083 (20130101) C04B 2237/365 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 12037914 | Phelps |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Joseph B. Phelps (Rocky Hill, Connecticut) |
| ABSTRACT | An assembly is provided for a turbine engine. This turbine engine assembly includes a rotating assembly and a sensor. The rotating assembly is configured to rotate about an axis. The rotating assembly includes an engine shaft, a phonic wheel and a lubricant scoop. The phonic wheel is mounted onto the engine shaft. The phonic wheel includes an outer surface and a plurality of apertures arranged circumferentially about the axis. Each of the apertures projects at least partially radially into the phonic wheel from the outer surface. The lubricant scoop is radially outboard of and axially overlaps the outer surface. The sensor is configured to measure fluctuations in a magnetic field induced by the phonic wheel during rotation of the rotating assembly about the axis. |
| FILED | Friday, May 26, 2023 |
| APPL NO | 18/202754 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 21/003 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2270/80 (20130101) F05D 2270/304 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/481 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12038061 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Tewksbury, Massachusetts) |
| INVENTOR(S) | Brett A. Miller (McKinney, Texas); Michael Martinez (McKinney, Texas) |
| ABSTRACT | A tuned mass absorber assembly comprises a mass structure, and a flexure system comprising first and second flexure sections (e.g., cross bar flexures) supported by, and extending in opposing directions from, the mass structure. The flexure system can comprise flexure section mounts situated at distal ends of the first and second flexure sections, respectively, and that are operable to mount the tuned mass absorber assembly to a structure subject to induced vibrations therein. A mass of the mass structure and a stiffness of the flexure system can be tuned to attenuate vibrations at a specific input frequency generated in response to induced vibrations of the structure. A system can comprise a vibration isolator attached to a chassis (e.g., of an airplane), and supporting a payload (sensors(s)) and isolating the payload from vibrations. A tuned mass absorber assembly can be mounted to the vibration isolator for attenuating vibrations at a specific input frequency that may affect the payload. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/539152 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Springs; Shock-absorbers; Means for Damping Vibration F16F 1/3814 (20130101) F16F 7/108 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 16, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240716.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page