FedInvent™ Patents
Patent Details for Tuesday, July 30, 2024
This page was updated on Tuesday, July 30, 2024 at 04:38 PM GMT
Department of Health and Human Services (HHS)
| US 12048511 | Asghar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (Boca Raton, Florida) |
| ASSIGNEE(S) | FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (Boca Raton, Florida) |
| INVENTOR(S) | Waseem Asghar (Boca Raton, Florida); Benjamin Coleman (Houston, Texas); Chad Coarsey (Boca Raton, Florida) |
| ABSTRACT | A video processing method improves the repeatability of point-of-care (POC) mean pixel intensity (MPI) analysis, for example by rejecting low-quality input data using image features. Using these features, the method selects high-quality frames and achieves an improvement in correlation and standard error for the MPI-absorbance relationship. In another example, a mobile device (e.g., smartphone) based image processing method produces an MPI output with smaller variances, lower limits of detection (LODs), and a higher dynamic range than existing methods. This method has improved performance in the presence of additive and multiplicative ambient light noise. |
| FILED | Monday, October 21, 2019 |
| APPL NO | 17/311893 |
| ART UNIT | 2671 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0077 (20130101) Original (OR) Class Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/2823 (20130101) Image or Video Recognition or Understanding G06V 10/17 (20220101) G06V 10/25 (20220101) G06V 10/56 (20220101) G06V 20/48 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048554 | Elwood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Epitel, Inc. (Salt Lake City, Utah) |
| ASSIGNEE(S) | Epitel, Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | Michael K. Elwood (Farmington, Utah); Mitchell A. Frankel (Salt Lake City, Utah); Mark J. Lehmkuhle (Salt Lake City, Utah); Jean M. Wheeler (Salt Lake City, Utah); Robert Lingstuyl (Salt Lake City, Utah); Erin M. West (Midvale, Utah); Tyler D. McGrath (Salt Lake City, Utah) |
| ABSTRACT | One embodiment provides a method, including: obtaining EEG data from one or more single channel EEG sensor worn by a user; classifying, using a processor, the EEG data as one of nominal and abnormal; and providing an indication associated with a classification of the EEG data. Other embodiments are described and claimed. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/861080 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0006 (20130101) A61B 5/291 (20210101) A61B 5/372 (20210101) A61B 5/374 (20210101) A61B 5/384 (20210101) A61B 5/742 (20130101) A61B 5/4094 (20130101) Original (OR) Class A61B 5/6814 (20130101) A61B 5/7264 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048565 | Calhoun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
| INVENTOR(S) | Vince Calhoun (Albuquerque, New Mexico); Jing Sui (Albuquerque, New Mexico) |
| ABSTRACT | The present invention is directed to a system and methods of predicting undiagnosed mental disorders in a patient and determining the best medication-class treatment for the mental disorder through the analysis of functional magnetic resonance imaging of functional connectivity of the brain representative of a certain mental disorder. |
| FILED | Tuesday, January 15, 2019 |
| APPL NO | 16/961626 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/165 (20130101) A61B 5/7267 (20130101) A61B 5/7275 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/10 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/70 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048584 | Parker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
| INVENTOR(S) | Kevin J. Parker (Rochester, New York); Jihye Baek (Rochester, New York) |
| ABSTRACT | An ultrasound study in which the reflected echoes are analyzed to determine a physical characteristic of scatterers within the volume of interest, the acoustic attenuation within the volume of interest, and the echo amplitude. These data are used to diagnose the disease state and the progression of disease. |
| FILED | Monday, January 31, 2022 |
| APPL NO | 17/649429 |
| ART UNIT | 3798 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/14 (20130101) Original (OR) Class A61B 8/085 (20130101) A61B 8/466 (20130101) A61B 8/483 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048679 | Machida |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Keigo Machida (Los Angeles, California) |
| ABSTRACT | The molecular mechanism of the function of TBC1D15 in NOTCH activation and stabilization is associated with maintenance and expansion of tumor-initiating stem-like cells (TICs). We herein demonstrate that TBC1D15 preferentially binds an NUMB isoform and NOTCH1-PEST domain and stabilizes NOTCH1 protein. This interaction enhances phosphorylation of NUMB, taking it away from NUMB-mediated ubiquitin degradation of NOTCH. Thus, TBC1D15 acts as a switch to augment NOTCH signaling in TICs. We also have identified inhibitors of TBC1D15 such as latanoprost acid and a salt thereof, which blocks the NOTCH-TBC1D15 interaction and selectively kills CD133-positive TICs, resulting in a reduction in the tumor size in a patient-derived, hepatocellular carcinoma xenograft model. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/716645 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/191 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048682 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Wenbin Lin (Chicago, Illinois); Christina Chan (Chicago, Illinois); Wenbo Han (Chicago, Illinois) |
| ABSTRACT | Nanoparticles comprising micheliolide (MCL) or derivatives thereof, and optionally additional therapeutic agents, such as chemotherapeutic agents, are described. Also described are methods of treating diseases, such as cancer, comprising the use of combinations of MCL or a derivative thereof with X-ray irradiation and/or other therapeutic agents, such as immune checkpoint inhibitors. The use of the combinations can provide synergistic anticancer therapeutic efficacy, for example, as the MCL or derivative thereof can both sensitize cancer cells to therapy and target resistant cancer stem cells (CSCs) for selective cell death. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/855327 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/343 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/6803 (20170801) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048686 | Moellering et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Raymond Moellering (Chicago, Illinois); John Coukos (Chicago, Illinois); Gihoon Lee (Chicago, Illinois); Jae Won Chang (Chicago, Illinois); Gokhan Mutlu (Chicago, Illinois) |
| ABSTRACT | Embodiments are directed to a series of novel small molecule activators of NRF2 dependent gene expression that are evaluated in an effort to develop therapeutic methods against diseases with deregulated KEAP1-NRF2 signaling. |
| FILED | Monday, October 14, 2019 |
| APPL NO | 17/309017 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/381 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048694 | Smallwood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital, Inc. (Memphis, Tennessee) |
| INVENTOR(S) | Heather Smallwood (Memphis, Tennessee); Marie Morfouace (Cambridge, United Kingdom); Martine F. Roussel (Memphis, Tennessee); Paul G. Thomas (Memphis, Tennessee) |
| ABSTRACT | The invention generally relates to methods of treating viral infections using known drugs and pharmaceutical compositions comprising same. More specifically, the disclosed methods are useful for the treatment of viral infections that are enveloped viruses. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Friday, May 07, 2021 |
| APPL NO | 17/315136 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/34 (20130101) A61K 31/34 (20130101) A61K 31/277 (20130101) A61K 31/352 (20130101) A61K 31/365 (20130101) A61K 31/415 (20130101) A61K 31/415 (20130101) A61K 31/416 (20130101) A61K 31/427 (20130101) A61K 31/427 (20130101) A61K 31/433 (20130101) A61K 31/433 (20130101) A61K 31/454 (20130101) A61K 31/454 (20130101) A61K 31/505 (20130101) A61K 31/505 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/555 (20130101) A61K 31/4164 (20130101) A61K 31/4164 (20130101) A61K 31/4174 (20130101) A61K 31/4439 (20130101) A61K 31/4745 (20130101) Original (OR) Class A61K 31/4745 (20130101) A61K 31/7004 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048701 | Yeager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mezzion Pharma Co., Ltd. (Seoul, South Korea); Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Mezzion Pharma Co., Ltd. (Seoul, South Korea); Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | James L. Yeager (Lake Forest, Illinois); David J. Goldberg (Philadelphia, Pennsylvania); Stephen M. Paridon (Strafford, Pennsylvania) |
| ABSTRACT | The present invention relates generally to the field of using udenafil or a pharmaceutically acceptable salt thereof in patients who have undergone the Fontan operation. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/102837 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/519 (20130101) A61K 31/522 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048710 | Bertozzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Carolyn Ruth Bertozzi (Berkeley, California); Nicholas J. Agard (Berkeley, California); Jennifer A. Prescher (Berkeley, California); Jeremy Michael Baskin (Berkeley, California); Ellen May Sletten (Berkeley, California) |
| ABSTRACT | The present invention provides modified cycloalkyne compounds; and method of use of such compounds in modifying biomolecules. The present invention features a cycloaddition reaction that can be carried out under physiological conditions. In general, the invention involves reacting a modified cycloalkyne with an azide moiety on a target biomolecule, generating a covalently modified biomolecule. The selectivity of the reaction and its compatibility with aqueous environments provide for its application in vivo (e.g., on the cell surface or intracellularly) and in vitro (e.g., synthesis of peptides and other polymers, production of modified (e.g., labeled) amino acids). |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/672508 |
| ART UNIT | 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/655 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 45/63 (20130101) C07C 45/63 (20130101) C07C 45/292 (20130101) C07C 45/292 (20130101) C07C 45/511 (20130101) C07C 45/511 (20130101) C07C 45/511 (20130101) C07C 45/511 (20130101) C07C 49/457 (20130101) C07C 49/457 (20130101) C07C 49/457 (20130101) C07C 49/573 (20130101) C07C 49/753 (20130101) C07C 49/753 (20130101) C07C 49/753 (20130101) C07C 57/26 (20130101) C07C 59/72 (20130101) C07C 63/66 (20130101) C07C 63/74 (20130101) C07C 69/76 (20130101) C07C 69/708 (20130101) C07C 2601/18 (20170501) Heterocyclic Compounds C07D 207/416 (20130101) C07D 207/452 (20130101) C07D 225/02 (20130101) C07D 249/16 (20130101) C07D 495/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/531 (20130101) G01N 33/6803 (20130101) G01N 33/6842 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048716 | Metelitsa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Leonid S. Metelitsa (Sugar Land, Texas); Amy N. Courtney (Houston, Texas); Gengwen Tian (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure include methods and compositions for producing NKT cells effective for immunotherapy and also methods and compositions for providing an effective amount of NKT cells to an individual in need of immunotherapy. In specific embodiments, the NKT cells are CD62L+ and have been exposed to one or more costimulatory agents to maintain CD62L expression. The NKT cells may be modified to incorporate a chimeric antigen receptor, in some cases. |
| FILED | Thursday, April 21, 2016 |
| APPL NO | 15/135453 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/178 (20130101) A61K 39/0011 (20130101) A61K 2035/124 (20130101) A61K 2039/5156 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/00 (20180101) Peptides C07K 16/2803 (20130101) C07K 16/3084 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/10 (20130101) C12N 5/0646 (20130101) C12N 2501/599 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048732 | Hansen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Blaze Bioscience, Inc. (Seattle, Washington) |
| ASSIGNEE(S) | Blaze Bioscience, Inc. (Seattle, Washington) |
| INVENTOR(S) | Stacey J. Hansen (Seattle, Washington); Julia E. Novak (Seattle, Washington) |
| ABSTRACT | Compositions and formulations comprising chlorotoxin conjugate compounds are provided, including native and modified variants of chlorotoxin peptide conjugated to detectable agents or active agents. Methods of detecting and treating ductal carcinoma in situ breast cancer, invasive ductal carcinoma breast cancer, lobular carcinoma in situ, invasive lobular carcinoma, and triple-negative breast cancer with chlorotoxin conjugate compounds are also provided, including methods of imaging tumor tissues and cells. |
| FILED | Friday, April 14, 2017 |
| APPL NO | 16/093508 |
| ART UNIT | RD00 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/337 (20130101) A61K 31/502 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/555 (20130101) A61K 31/704 (20130101) A61K 33/243 (20190101) A61K 38/1767 (20130101) Original (OR) Class A61K 47/6415 (20170801) A61K 49/0032 (20130101) A61K 49/0056 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/00 (20130101) C07K 14/43522 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048740 | Bakaletz |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio) |
| ASSIGNEE(S) | RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio) |
| INVENTOR(S) | Lauren O. Bakaletz (Hilliard, Ohio) |
| ABSTRACT | Provided are topical delivery systems and methods for treating and/or preventing a disease or disorder in a subject, or for eliciting an immune response in a subject including applying, to at least a portion of the subject's post-auricular region, a topical delivery system including a therapeutically effective amount of a topical pharmaceutical composition comprising at least one active agent and a pharmaceutically acceptable carrier and/or adjuvant. The topical pharmaceutical composition can include a topical immunogenic composition. The topical delivery system can further include a flexible substrate in communication with the topical immunogenic composition. The subject can be a pediatric subject. |
| FILED | Tuesday, July 07, 2020 |
| APPL NO | 16/922725 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/7084 (20130101) A61K 39/102 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 2039/54 (20130101) A61K 2039/60 (20130101) A61K 2039/541 (20130101) A61K 2039/545 (20130101) A61K 2039/6068 (20130101) A61K 2039/55544 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048741 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | George Mason University (Fairfax, Virginia) |
| ASSIGNEE(S) | GEORGE MASON UNIVERSITY (Fairfax, Virginia) |
| INVENTOR(S) | Yuntao Wu (Manassas, Virginia); Deemah Dabbagh (Fairfax, Virginia); Sijia He (Manassas, Virginia); Brian Hetrick (Woodbridge, Virginia) |
| ABSTRACT | Recombinant viruses include one or more SHREK proteins and are thereby rendered non-infective and can be safely used in vaccines, e.g. to treat or prevent infections and to eliminate e.g. latent virus reservoirs. |
| FILED | Thursday, September 24, 2020 |
| APPL NO | 17/031082 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/162 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 2039/507 (20130101) A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048750 | Hansen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Blaze Bioscience, Inc. (Seattle, Washington) |
| ASSIGNEE(S) | Blaze Bioscience, Inc. (Seattle, Washington) |
| INVENTOR(S) | Stacey J. Hansen (Renton, Washington); Claudia Jochheim (Seattle, Washington); Dennis M. Miller (Woodinville, Washington); Natalie Winblade Nairn (Seattle, Washington); Julia E. Novak (Sequim, Washington); Mark R. Stroud (Seattle, Washington); Valorie R. Wiss (Moscow, Idaho); Kelly Byrnes-Blake (Sultan, Washington); Scott Presnell (Tacoma, Washington) |
| ABSTRACT | Peptides that home, target, migrate to, are directed to, are retained by, or accumulate in and/or bind to the cartilage or kidney of a subject are disclosed. Pharmaceutical compositions and uses for peptides or peptide-active agent complexes comprising such peptides are also disclosed. Such compositions can be formulated for targeted delivery of an active agent to a target region, tissue, structure or cell in the cartilage. Targeted compositions of the disclosure can deliver peptide or peptide-active agent complexes to target regions, tissues, structures, or cells targeted by the peptide. |
| FILED | Monday, August 15, 2022 |
| APPL NO | 17/888072 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0071 (20130101) A61B 6/037 (20130101) A61B 6/481 (20130101) A61B 6/4057 (20130101) A61B 8/481 (20130101) A61B 2505/05 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 47/65 (20170801) A61K 47/6415 (20170801) Original (OR) Class A61K 49/0056 (20130101) A61K 49/0058 (20130101) A61K 51/08 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) A61P 19/02 (20180101) Peptides C07K 14/4726 (20130101) C07K 14/43518 (20130101) C07K 14/43522 (20130101) C07K 16/244 (20130101) C07K 16/248 (20130101) C07K 2319/30 (20130101) C07K 2319/33 (20130101) C07K 2319/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048753 | Rashidian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Mohammad Rashidian (Cambridge, Massachusetts); Hidde L. Ploegh (Jamaica Plain, Massachusetts) |
| ABSTRACT | Provided herein are methods for producing site specific PEG modifications to single domain antibodies (e.g., VHHs). Methods for producing site-specifically conjugated bivalent single domain antibodies (e.g., VHHs) are also provided. Methods for labeling (e.g., with a fluorophore or radionuclide) site-specifically PEGylated single domain antibodies and site-specifically conjugated bivalent single domain antibodies are also provided. |
| FILED | Saturday, October 01, 2016 |
| APPL NO | 15/764087 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/1021 (20130101) A61K 51/1027 (20130101) A61K 51/1093 (20130101) Original (OR) Class A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/247 (20130101) C07K 16/2833 (20130101) C07K 16/2845 (20130101) C07K 2317/22 (20130101) C07K 2317/35 (20130101) C07K 2317/569 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) Enzymes C12Y 304/22 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048779 | Bhumiratana et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Sarindr Bhumiratana (Oceanside, New York); Gordana Vunjak-Novakovic (New York, New York) |
| ABSTRACT | Medical devices having engineered mechanically functional cartilage from adult human mesenchymal stem cells and method for making same. |
| FILED | Thursday, October 21, 2021 |
| APPL NO | 17/506831 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/3094 (20130101) A61F 2/30756 (20130101) A61F 2002/30762 (20130101) A61F 2002/30766 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/46 (20130101) A61L 27/46 (20130101) A61L 27/50 (20130101) A61L 27/56 (20130101) A61L 27/425 (20130101) A61L 27/3608 (20130101) A61L 27/3612 (20130101) Original (OR) Class A61L 27/3834 (20130101) A61L 2400/06 (20130101) A61L 2430/06 (20130101) A61L 2430/10 (20130101) Compositions of Macromolecular Compounds C08L 89/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048928 | Eltoukhy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Illumina, Inc. (San Diego, California) |
| ASSIGNEE(S) | ILLUMINA, INC. (San Diego, California) |
| INVENTOR(S) | Helmy A. Eltoukhy (San Diego, California); Tarun Khurana (San Diego, California); Behnam Javanmardi (San Diego, California); Poorya Sabounchi (San Diego, California); Majid Aghababazadeh (San Diego, California) |
| ABSTRACT | A flow cell including inlet and outlet ports in fluid communication with each other through a flow channel that extends therebetween. The flow channel includes a diffuser region and a field region that is located downstream from the diffuser region. The field region of the flow channel directs fluid along reaction sites where desired reactions occur. The fluid flows through the diffuser region in a first flow direction and through the field region in a second flow direction. The first and second flow directions being substantially perpendicular. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 17/848840 |
| ART UNIT | 1796 — Fluid Handling and Dispensing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 7/52 (20130101) B01L 2200/04 (20130101) B01L 2200/10 (20130101) B01L 2200/16 (20130101) B01L 2200/025 (20130101) B01L 2200/082 (20130101) B01L 2300/022 (20130101) B01L 2300/023 (20130101) B01L 2300/048 (20130101) B01L 2300/161 (20130101) B01L 2300/165 (20130101) B01L 2300/0627 (20130101) B01L 2300/0636 (20130101) B01L 2300/0645 (20130101) B01L 2300/0654 (20130101) B01L 2300/0819 (20130101) B01L 2300/0877 (20130101) B01L 2400/0457 (20130101) B01L 2400/0487 (20130101) B01L 2400/0622 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049449 | Frederich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | James H. Frederich (Tallahassee, Florida); James A. Law (Tallahassee, Florida) |
| ABSTRACT | Methods of hydromethylation of alkenes and ketones, including methods that use Tebbe's reagent. The methods may include contacting Cp2Ti(μ-Cl)(μ-CH2)AlMe2 and an alkene or a ketone to produce an intermediate product that may include a titanacyclobutane. The intermediate product may be contacted with an acid to produce a methylated product. |
| FILED | Monday, July 26, 2021 |
| APPL NO | 17/385528 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 211/96 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049478 | Asokan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Aravind Asokan (Chapel Hill, North Carolina); Richard Samulski (Hillsborough, North Carolina) |
| ABSTRACT | The present invention provides methods and compositions comprising an adeno-associated virus (AAV) capsid protein, comprising one or more amino acids substitutions, wherein the substitutions introduce a new glycan binding site into the AAV capsid protein. |
| FILED | Friday, December 11, 2020 |
| APPL NO | 17/119308 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/075 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/861 (20130101) C12N 2750/14122 (20130101) C12N 2750/14141 (20130101) C12N 2750/14142 (20130101) C12N 2750/14171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049481 | Omenetto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tufts University (Medford, Massachusetts) |
| ASSIGNEE(S) | Tufts University (Medford, Massachusetts) |
| INVENTOR(S) | Fiorenzo G. Omenetto (Lexington, Massachusetts); David L. Kaplan (Concord, Massachusetts); Benedetto Marelli (Lexington, Massachusetts); Alexander Nicholas Mitropoulos (Winchester, Massachusetts) |
| ABSTRACT | The present application relates to silk fibroin-based hydrogels, methods for making and using the same. |
| FILED | Tuesday, May 12, 2020 |
| APPL NO | 16/872679 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 47/42 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) A61L 27/56 (20130101) A61L 27/227 (20130101) A61L 27/3813 (20130101) A61L 2400/12 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/361 (20151001) B23K 26/402 (20130101) B23K 2103/32 (20180801) B23K 2103/38 (20180801) B23K 2103/50 (20180801) Peptides C07K 14/43586 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0068 (20130101) C12N 2533/50 (20130101) C12N 2533/90 (20130101) C12N 2537/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049482 | Jan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); THE BRIGHAM and WOMEN'S HOSPITAL, INC. (Boston, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Max Jan (Boston, Massachusetts); Quinlan L. Sievers (Boston, Massachusetts); Benjamin Ebert (Boston, Massachusetts); Marcela Maus (Boston, Massachusetts) |
| ABSTRACT | The present disclosure relates to therapeutic methods and clinically useful molecular switches, for which activity or degradation of a switch-presenting polypeptide can be precisely induced via administration or withdrawal of an FDA-approved drug. Certain aspects of the disclosure relate to an engineered drug-inducible heterodimeric system including a first polypeptide presenting a CRBN polypeptide disrupted for or lacking a DDB 1-interacting domain and a second polypeptide presenting a CRBN polypeptide substrate, where binding between the CRBN polypeptide and the CRBN polypeptide substrate are inducible via administration of an CFDA-approved thalidomide analog immunomodulatory drug (IMiD). Another aspect of the disclosure relates to a chimeric antigen receptor (CAR) that presents a minimal fragment of the CRBN polypeptide substrate IKZF3 capable of triggering proteasomal degradation of CAR upon administration of an FDA-approved IMiD. |
| FILED | Tuesday, October 30, 2018 |
| APPL NO | 16/759490 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/4702 (20130101) Original (OR) Class C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/00 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049483 | Koide et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Shohei Koide (New York, New York); Kai Wen Teng (Flushing, New York); Akiko Koide (New York, New York); Takamitsu Hattori (West New York, New York) |
| ABSTRACT | Provided are proteins or peptides, which may be referred to as monobodies. Fusion proteins and proteolysis targeting chimeras (PROTACs) comprising the proteins or peptides are also provided. Also provided are compositions of the proteins or peptides of the present disclosure, as well as compositions of fusion proteins and compositions of PROTACs. Methods of treating an individual in need of treatment are also provided. The methods may be to treat an individual suffering from or suspected of having KRAS(G12V), KRAS(G12S), KRAS(G12A) and/or KRAS(G12C)-associated cancers. A method may be for inhibiting ERK activation and/or proliferation of KRAS(G12V), KRAS(G12S), KRAS(G12A) and/or KRAS(G12C)-associated cancers. |
| FILED | Monday, December 06, 2021 |
| APPL NO | 17/543464 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Peptides C07K 14/4702 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049492 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Dongfang Liu (Millburn, New Jersey); Minh Ma (New Brunswick, New Jersey); Saiaditya Badeti (New Brunswick, New Jersey) |
| ABSTRACT | Chimeric antigen receptors (CARs) including an antigen binding domain specifically binding to coronavirus spike protein, nucleic acids encoding the CARs, vectors including nucleic acids encoding the CARs, and immune cells expressing the CARs are provided. Methods of treating a subject with coronavirus, including administering to the subject an immune cell expressing a disclosed CAR are also provided. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 17/399993 |
| ART UNIT | 1638 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) A61K 35/17 (20130101) A61K 39/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/7151 (20130101) C07K 14/70521 (20130101) C07K 16/10 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/53 (20130101) C07K 2317/56 (20130101) C07K 2317/565 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6472 (20130101) Enzymes C12Y 304/22062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049521 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Jun O. Liu (Clarksville, Maryland); Jingxin Wang (Baltimore, Maryland); Zufeng Guo (Baltimore, Maryland); Wei Li (Xiangtan, China PRC); Shridhar Bhat (Cockeysville, Maryland); Manisha Das (Centreville, Virginia) |
| ABSTRACT | Provided are novel types of hybrid cyclic libraries that contain a known protein binding domain of a natural product. Also provided are synthetic methods to make such libraries and methods for the deconvolution of hits using partially split-pooled library compounds. Such methods are applicable for use with the entire human proteome to screen such libraries that bind and for the identification of hits. |
| FILED | Thursday, February 25, 2021 |
| APPL NO | 17/185658 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/4353 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) C07D 498/04 (20130101) C07D 498/14 (20130101) C07D 515/04 (20130101) C07D 515/14 (20130101) Peptides C07K 7/645 (20130101) Original (OR) Class C07K 17/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049624 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bo Huang (San Francisco, California); Baohui Chen (San Francisco, California); Lei Qi (Berkeley, California); Luke Gilbert (San Francisco, California) |
| ABSTRACT | Methods, compositions, and kits are provided herein for CRISPER/Cas-mediated nucleic acid detection or modification. |
| FILED | Friday, September 25, 2020 |
| APPL NO | 17/033255 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 2310/10 (20130101) C12N 2310/20 (20170501) C12N 2310/531 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049625 | Krichevsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Anna M. Krichevsky (Brookline, Massachusetts); Rachid El-Fatimy (Brighton, Massachusetts); Erik J. Uhlmann (Newton Center, Massachusetts) |
| ABSTRACT | A method of treating a subject who has a glioma, e.g., astrocytoma, oligodendroglioma, or glioblastoma multiforme tumor, the method comprising administering to the subject a therapeutically effective amount of a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) microRNA-10b (miR-10b) editing complex comprising a CRISPR Associated Protein 9 (Cas9) and at least one guide RNA targeting a sequence encoding miR-10b. |
| FILED | Friday, January 13, 2017 |
| APPL NO | 16/069727 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 31/7088 (20130101) A61K 38/465 (20130101) A61K 48/0066 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/113 (20130101) C12N 2800/80 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049627 | Khvorova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Julia Alterman (Worcester, Massachusetts); Matthew Hassler (Worcester, Massachusetts) |
| ABSTRACT | Provided are compositions and methods comprising two-tailed siRNAs (tt-siRNAs) that exhibit unprecedented cellular uptake and silencing. Also provided are methods of treating neurological and other diseases with the two-tailed siRNAs of the invention. |
| FILED | Thursday, October 15, 2020 |
| APPL NO | 17/071473 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/314 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/322 (20130101) C12N 2310/343 (20130101) C12N 2310/344 (20130101) C12N 2310/346 (20130101) C12N 2310/3521 (20130101) C12N 2310/3533 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049639 | Chatterjee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The USA as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Deb K. Chatterjee (Potomac, Maryland); Stanislaw J. Kaczmarczyk (Frederick, Maryland) |
| ABSTRACT | Described herein is a method of preventing or treating a disease in a mammalian subject, comprising administering to the subject who is in need thereof an effective dosage of a pharmaceutical composition comprising a virus like particle (VLP) comprising: an alphavirus replicon comprising a recombinant polynucleotide, wherein the polynucleotide comprises a sequence encoding both subunits of a human class II major histocompatibility antigen, a retroviral gag protein, and a fusogenic envelope protein, wherein the VLP does not contain an alphavirus structural protein gene. |
| FILED | Friday, February 24, 2023 |
| APPL NO | 18/174013 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 39/001117 (20180801) A61K 39/001124 (20180801) A61K 39/001129 (20180801) A61K 39/001144 (20180801) A61K 39/001152 (20180801) A61K 39/001163 (20180801) A61K 39/001181 (20180801) A61K 39/001182 (20180801) A61K 39/001191 (20180801) A61K 39/001194 (20180801) A61K 45/06 (20130101) A61K 2039/53 (20130101) A61K 2039/585 (20130101) A61K 2039/5258 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2740/11023 (20130101) C12N 2740/11042 (20130101) C12N 2770/36123 (20130101) C12N 2770/36134 (20130101) C12N 2770/36143 (20130101) C12N 2770/36145 (20130101) C12N 2770/36152 (20130101) C12N 2770/36171 (20130101) C12N 2800/24 (20130101) C12N 2810/6081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049643 | Regev et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Ana C. Anderson (Boston, Massachusetts); Vijay K. Kuchroo (Boston, Massachusetts); Sema Kurtulus (Boston, Massachusetts); Asaf Madi (Boston, Massachusetts) |
| ABSTRACT | The subject matter disclosed herein is generally directed to novel CD8+ tumor infiltrating lymphocyte (TIL) subtypes associated with response to immunotherapy treatment. Specifically, the subtypes are associated with checkpoint blockade therapy. Moreover, the subject matter disclosed herein is generally directed to methods and compositions for use of the subtypes. Also, disclosed herein are gene signatures and markers associated with the subtypes and use of said signatures and markers. Further disclosed are therapeutic methods of using said gene signatures and immune cell subtypes. Further disclosed are pharmaceutical compositions comprising populations of CD8+ TILs enriched for a specific subtype. |
| FILED | Friday, July 13, 2018 |
| APPL NO | 16/630887 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/70503 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049644 | Klemke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (La Jolla, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Richard Klemke (La Jolla, California); Huawei Wang (San Diego, California) |
| ABSTRACT | Provided are cytoplasts (enucleated cells), methods for making cytoplasts, compositions comprising cytoplasts, and methods for using cytoplasts. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/145848 |
| ART UNIT | 1638 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/12 (20130101) A61K 35/17 (20130101) A61K 35/28 (20130101) A61K 38/208 (20130101) A61K 38/2066 (20130101) A61K 39/215 (20130101) A61K 39/001102 (20180801) A61K 2039/515 (20130101) A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/10 (20130101) C12N 5/0646 (20130101) C12N 5/0662 (20130101) Original (OR) Class C12N 5/0667 (20130101) C12N 15/85 (20130101) C12N 15/88 (20130101) C12N 2501/999 (20130101) C12N 2510/00 (20130101) C12N 2513/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049648 | Gradinaru et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Viviana Gradinaru (Pasadena, California); Nicholas C. Flytzanis (Thousand Oaks, California); Nicholas S. Goeden (Thousand Oaks, California) |
| ABSTRACT | Described herein are compositions and kits comprising recombinant adeno-associated viruses (rAAVs) with tropisms showing increased specificity and efficiency of viral transduction in targeted cell types such as the brain and lung. The rAAV compositions described herein also have tropisms showing decreased specificity and decreased efficiency of viral transduction in an off-target cell type such as the liver. The rAAV compositions described herein encapsidate a transgene, such as a therapeutic nucleic acid. Upon systemic delivery to a subject, the rAAV is capable of increased specificity and increased transduction of the transgene in a target cell-type, as compared to a parental or reference AAV. |
| FILED | Monday, October 18, 2021 |
| APPL NO | 17/503972 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2750/14071 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049653 | Griswold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Karl E. Griswold (Lyme, New Hampshire); Hongliang Zhao (Hanover, New Hampshire) |
| ABSTRACT | Unglycosylated lysostaphin variant protein, nucleic acid molecule, vector and host cell, as well as a method for production of unglycosylated lysostaphin variant protein in a yeast expression system are provided. The proteins are produced in a Pichia pastoris expression system and have been shown to have activity equivalent to wild-type lysostaphin. The lysostaphin variant proteins can be used as therapeutic proteins for treatment of diseases such as Staphylococcus aureus infection. |
| FILED | Tuesday, September 21, 2021 |
| APPL NO | 17/480166 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class Enzymes C12Y 304/24075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049662 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Shaopeng Wang (Chandler, Arizona); Fenni Zhang (Tempe, Arizona) |
| ABSTRACT | Provided herein are methods of assessing the presence of microbes in a liquid sample that include assessing an initial integrated scattering intensity of objects (IC0) in the sample and an integrated scattering intensity of the objects at a time t (ICt) from modified images of the liquid sample, and identifying the sample as comprising microbes for (ICt)/(IC0) above a predefined infection threshold TI. Related systems and other aspects are also provided. |
| FILED | Tuesday, February 01, 2022 |
| APPL NO | 17/590457 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/06 (20130101) Original (OR) Class C12Q 1/18 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) G06T 7/246 (20170101) G06T 2207/10056 (20130101) G06T 2207/30024 (20130101) G06T 2207/30241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050189 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Xudong Wu (Cambridge, Massachusetts); Tom A. Rapoport (Cambridge, Massachusetts) |
| ABSTRACT | The technology described herein is directed to structural analysis, particularly of small proteins via cryo-EM. |
| FILED | Thursday, September 08, 2022 |
| APPL NO | 17/930483 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/195 (20130101) C07K 14/705 (20130101) C07K 16/465 (20130101) C07K 2299/00 (20130101) C07K 2317/569 (20130101) C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20 (20130101) Original (OR) Class G01N 33/6845 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050201 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Lihong Wang (Arcadia, California); Liang Song (St. Louis, Missouri); Konstantin Maslov (Pasadena, California); Bin Rao (St. Louis, Missouri) |
| ABSTRACT | A probe for use with an imaging system, including a scanning device configured to receive a first light beam from a light source, a beam-divider configured to split the first light beam into a plurality of second light beams, and a focusing device configured to focus each of the second light beams on respective locations in an object of interest is disclosed. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/302313 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/42 (20130101) A61B 5/0095 (20130101) A61B 5/441 (20130101) A61B 5/4064 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/2418 (20130101) Original (OR) Class G01N 2291/028 (20130101) G01N 2291/106 (20130101) Optical Elements, Systems, or Apparatus G02B 21/36 (20130101) G02B 26/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050215 | Takayama et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Shuichi Takayama (Ann Arbor, Michigan); Cameron Louttit (Ann Arbor, Michigan); James J. Moon (Ann Arbor, Michigan); Taisuke Kojima (Ann Arbor, Michigan); Priyan Weerappuli (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein are macromolecular structures comprising charged macromolecules. In particular, provided herein are synthetic neutrophil extracellular traps and uses thereof. |
| FILED | Wednesday, November 16, 2016 |
| APPL NO | 15/776346 |
| ART UNIT | 1675 — Printing/Measuring and Testing |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/10 (20130101) A01N 57/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/089 (20200101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/544 (20130101) Original (OR) Class G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050227 | Ramamoorthy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); NARA INSTITUTE OF SCIENCE AND TECHNOLOGY (Ikoma, Japan) |
| ASSIGNEE(S) | Nara Institute of Science and Technology (Ikoma, Japan); THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Ayyalusamy Ramamoorthy (Ann Arbor, Michigan); Thirupathi Ravula (Ann Arbor, Michigan); Bikash Sahoo (Ann Arbor, Michigan); Kazuma Yasuhara (Ikoma, Japan); Jin Arakida (Ikoma, Japan); Jun-Ichi Kikuchi (Ikoma, Japan) |
| ABSTRACT | The disclosure generally relates generally to lipid nanodiscs, in particular to lipid nanodiscs formed from acryloyl-based copolymers. A lipid nanodisc according to the disclosure includes a lipid bilayer having a first hydrophilic face and a second hydrophilic face opposing the first hydrophilic face, and a hydrophobic edge between the opposing hydrophilic faces, and an acryloyl-based copolymer encircling the hydrophobic edge of the lipid bilayer. The acryloyl-based copolymer includes a first monomer unit having a pendant hydrophobic group and a second monomer unit having a pendant hydrophilic group. Methods of making and characterizing the lipid nanodiscs are also disclosed. |
| FILED | Wednesday, April 17, 2019 |
| APPL NO | 16/386804 |
| ART UNIT | 1758 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1273 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/14 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 2333/575 (20130101) G01N 2405/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050257 | Dosenbach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri); Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri); Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Nico Dosenbach (St. Louis, Missouri); Jonathan Koller (St. Louis, Missouri); Andrew Van (St. Louis, Missouri); Abraham Snyder (St. Louis, Missouri); Amy Mirro (St. Louis, Missouri); Damien Fair (Portland, Oregon); Eric Earl (Portland, Oregon); Rachel Klein (Portland, Oregon); Oscar Miranda Dominguez (Tigard, Oregon); Anders Perrone (Portland, Oregon) |
| ABSTRACT | Methods, computer-readable storage devices, and systems are described for reducing movement of a patient undergoing a magnetic resonance imaging (MRI) scan by aligning MRI data, the method implemented on a Framewise Integrated Real-time MRI Monitoring (“FIRMM”) computing device including at least one processor in communication with at least one memory device. Aspects of the method comprise receiving a data frame from the MRI system, aligning the received data frame to a preceding data frame, calculating motion of a body part between the received data frame and the preceding data frame, calculating total frame displacement, and excluding data frames with a cutoff above a pre-identified threshold of the total frame displacement. |
| FILED | Friday, December 02, 2022 |
| APPL NO | 18/061254 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0041 (20130101) G01R 33/4831 (20130101) G01R 33/5608 (20130101) G01R 33/56509 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051134 | Cong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa); Shandong University (Shandong, China PRC); Shandong Public Health Clinical Center (Jinan, China PRC); Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | University of Iowa Research Foundation (Iowa City, Iowa); Rensselaer Polytech Institute (, China PRC); Shandong University (, China PRC); Shandong Public Health Clinical Center (, China PRC) |
| INVENTOR(S) | Wenxiang Cong (Troy, New York); Ye Yangbo (Coralville, Iowa); Ge Wang (Troy, New York); Shuwei Mao (Jinan, China PRC); Yingmei Wang (Jinan, China PRC) |
| ABSTRACT | The disclosed apparatus, systems and methods relate to a framelet-based iterative algorithm for polychromatic CT which can reconstruct two components using a single scan. The algorithm can have various steps including a scaled-gradient descent step of constant or variant step sizes; a non-negativity step; a soft thresholding step; and a color reconstruction step. |
| FILED | Monday, March 08, 2021 |
| APPL NO | 17/194946 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) Image Data Processing or Generation, in General G06T 11/003 (20130101) G06T 11/005 (20130101) G06T 11/006 (20130101) Original (OR) Class G06T 2211/408 (20130101) G06T 2211/424 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12048303 | Pomahac et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Bohdan Pomahac (Boston, Massachusetts); Maximilian Kückelhaus (Boston, Massachusetts) |
| ABSTRACT | Systems and methods to perfuse isolated tissue are provided to avoid ischemia-related tissue damage over an extended perfusion time is provided. A system can comprise a reservoir sized and dimensioned to contain a perfusate. A perfusion supply line can comprise a pump, a cooling system, an oxygenator, and at least one filter. The perfusion supply line can be in fluid communication with the reservoir to draw the perfusate from the reservoir and cool and oxygenate the perfusate. The system can also include an arterial line in fluid communication with the perfusion supply line to direct perfusate from the reservoir to the isolated tissue. A venous outflow can be in fluid communication with the isolated tissue to remove the perfusate from the isolated tissue. A perfusion return line can be in fluid communication with the venous outflow to return the perfusate from the isolated tissue to the reservoir. |
| FILED | Wednesday, April 17, 2019 |
| APPL NO | 17/253741 |
| ART UNIT | 1799 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/021 (20130101) A01N 1/0247 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048553 | Romano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Anthony J Romano (Washington, District of Columbia); William G. Szymczak (Potomac, Maryland) |
| ABSTRACT | Systems and methods are provided for medical diagnosis and analysis using mixed model inversions. For example, a medical analyzer using mixed model inversions according to an embodiment of the present disclosure can be used to diagnose traumatic brain injury (TBI), which allows for isotropic and anisotropic inversions to be performed, enabling more accurate information about brain stiffness to be obtained. |
| FILED | Tuesday, April 14, 2020 |
| APPL NO | 16/848244 |
| ART UNIT | 3797 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/4064 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/30 (20130101) G01R 33/50 (20130101) G01R 33/5608 (20130101) G01R 33/56341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048668 | Sarkisian et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | The University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Sergei V. Sarkisian (Midvale, Utah); Tommaso Lenzi (Salt Lake City, Utah); Dante Amico Bennett Archangeli (Salt Lake City, Utah) |
| ABSTRACT | An exoskeleton device that includes an artificial joint and a frame member extending from the artificial joint. The frame member is configured for extension over a limb of a user. The exoskeleton device also includes a self-aligning mechanism connected to the frame member. The self-aligning mechanism includes three passive degrees of freedom (pDOF) provided in a prismatic-revolute-revolute (PRR) configuration. The self-aligning mechanism also includes a limb attachment member configured for mechanically coupling to a portion of the limb of the user. |
| FILED | Friday, March 19, 2021 |
| APPL NO | 17/911526 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/024 (20130101) A61H 1/0244 (20130101) A61H 3/00 (20130101) Original (OR) Class A61H 2003/007 (20130101) A61H 2201/123 (20130101) A61H 2201/164 (20130101) A61H 2201/165 (20130101) A61H 2201/1436 (20130101) A61H 2201/1673 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049028 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Loon-Seng Tan (Centerville, Ohio); David H. Wang (Beavercreek, Ohio) |
| ABSTRACT | The invention generally relates to polymer nanocomposite films that possess shape memory properties at elevated temperatures. Such films can absorb microwaves, are thermally conductive, are electrically conductive and have increased mechanical strength. In addition, the present invention relates to methods of fabricating such films into 3D objects. Due to the improved properties of such films more advanced sensors and microwave shields can be constructed. |
| FILED | Wednesday, January 11, 2023 |
| APPL NO | 18/095845 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/003 (20130101) Original (OR) Class B29C 41/46 (20130101) B29C 2791/001 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2079/085 (20130101) B29K 2105/246 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/14 (20130101) C08G 73/1007 (20130101) C08G 73/1067 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/041 (20170501) C08K 3/042 (20170501) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 79/08 (20130101) C08L 2201/12 (20130101) C08L 2312/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049304 | Olson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Eric Stephen Olson (Fort Worth, Texas) |
| ABSTRACT | A tail rotor isolation system for rotorcraft includes a secondary engine, first and second freewheeling units, an isolation assembly and a tail rotor system. The secondary engine is coupled to the input race of the first freewheeling unit. A main rotor system is coupled to the output race of the second freewheeling unit. The isolation assembly is coupled to the output race of the first freewheeling unit and has a fully engaged position coupling the input and output races of the second freewheeling unit and a partially engaged position coupled to the input race but decoupled from the output race of the second freewheeling unit. The tail rotor system is coupled to the input race of the second freewheeling unit such that in the partially engaged position of the isolation assembly, the overrunning mode of the second freewheeling unit isolates the tail rotor system from the main rotor system. |
| FILED | Monday, July 11, 2022 |
| APPL NO | 17/861702 |
| ART UNIT | 3659 — Material and Article Handling |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/12 (20130101) Original (OR) Class Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/026 (20240101) B64D 35/08 (20130101) Couplings for Transmitting Rotation; Clutches; Brakes F16D 41/04 (20130101) F16D 2041/0603 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049403 | Yeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Che-Ning Yeh (Union City, California); Jiaxing Huang (Wilmette, Illinois) |
| ABSTRACT | Graphene oxide doughs are provided. Also provided are dense, glassy solids made from the doughs and methods of making the doughs and the solids. The doughs and solids have high graphene oxide or reduced graphene oxide contents, and the sheets in the doughs and solids lack long-range lamellar stacking order. |
| FILED | Friday, September 13, 2019 |
| APPL NO | 17/274889 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/198 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/82 (20130101) C01P 2006/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049648 | Gradinaru et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Viviana Gradinaru (Pasadena, California); Nicholas C. Flytzanis (Thousand Oaks, California); Nicholas S. Goeden (Thousand Oaks, California) |
| ABSTRACT | Described herein are compositions and kits comprising recombinant adeno-associated viruses (rAAVs) with tropisms showing increased specificity and efficiency of viral transduction in targeted cell types such as the brain and lung. The rAAV compositions described herein also have tropisms showing decreased specificity and decreased efficiency of viral transduction in an off-target cell type such as the liver. The rAAV compositions described herein encapsidate a transgene, such as a therapeutic nucleic acid. Upon systemic delivery to a subject, the rAAV is capable of increased specificity and increased transduction of the transgene in a target cell-type, as compared to a parental or reference AAV. |
| FILED | Monday, October 18, 2021 |
| APPL NO | 17/503972 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2750/14071 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049904 | Ditomasso et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | John C. Ditomasso (Glastonbury, Connecticut); Matthew P. Forcier (South Windsor, Connecticut) |
| ABSTRACT | A tandem rotor disk apparatus may include a rotor disk body concentric about an axis. The tandem rotor disk apparatus may also include a first blade extending radially outward of the rotor disk body and a second blade extending radially outward of the rotor disk body. The first blade may be offset from the second blade in a direction parallel to the axis. The tandem rotor disk apparatus may be implemented in a gas turbine engine with no intervening stator vane stages disposed between the first blade and the second blade. |
| FILED | Wednesday, December 07, 2022 |
| APPL NO | 18/077084 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/34 (20130101) F01D 5/142 (20130101) F01D 5/146 (20130101) F01D 5/3007 (20130101) F01D 5/3038 (20130101) F01D 9/041 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/04 (20130101) Non-positive-displacement Pumps F04D 19/02 (20130101) F04D 29/321 (20130101) F04D 29/322 (20130101) F04D 29/324 (20130101) Original (OR) Class F04D 29/644 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049943 | Ott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Textron Innovations, Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations, Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Charles J. Ott (Keller, Texas); Austin McIntire (Fort Worth, Texas) |
| ABSTRACT | Flexured sun gears for planetary gear systems. In embodiments, a sun gear includes a spline section configured to couple the sun gear to another component, a gear section configured to mesh with at least one other gear of the planetary gear system, and a flexure section configured to couple the spline section to the gear section. The flexure section of the sun gear may have a flexure wall and a flexure curve, and has a thickness (e.g., in at least a portion of the flexure section) that is smaller than a thickness of the spline section and/or the gear section. The flexure section may enable the gear section to displace or move radially with respect to the spline section in response to a rotational force. For example, the flexure section may not move axially (e.g., may not extend) but may bend and/or rotate in response to the rotational force. |
| FILED | Monday, August 28, 2023 |
| APPL NO | 18/457146 |
| ART UNIT | 3655 — Material and Article Handling |
| CURRENT CPC | Gearing F16H 1/26 (20130101) F16H 1/2845 (20130101) Original (OR) Class F16H 1/2863 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050008 | Schmitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Spark Thermionics, Inc. (Berkeley, California) |
| ASSIGNEE(S) | Spark Thermionics, Inc. (Berkeley, California) |
| INVENTOR(S) | Felix Schmitt (Berkeley, California); Jared William Schwede (Berkeley, California); David Rich (Berkeley, California); Tyler Sandberg (Berkeley, California) |
| ABSTRACT | A burner system, preferably including input plumbing, a combustion region, and an exhaust section. In some embodiments, the burner system can include, be attached to, be configured to couple with, and/or be otherwise associated with a thermionic energy converter (TEC). A method of burner system operation, preferably including operating the burner system in a combustion mode and optionally including operating a TEC. |
| FILED | Wednesday, December 21, 2022 |
| APPL NO | 18/086082 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Burners F23D 91/02 (20150701) Original (OR) Class F23D 2900/3102 (20210501) Electric Discharge Tubes or Discharge Lamps H01J 45/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050039 | Roman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Abdeel Roman (Dayton, Ohio) |
| ABSTRACT | A unique cooling system for an aircraft is designed to provide extremely low temperature cooling airflow. The system includes an air source, a first system compressor and a second system compressor positioned in series for compressing and heating the air. A least one heat exchanger can be used to cool the air at predefined locations. A condenser for condensing water out of the air is positioned downstream of the second compressor. The water can be removed with a water separator and at least a portion of any remaining water in the form of liquid or vapor is removed from the air in a membrane dehydration device. The air is expanded in at least one system turbine to bring the air temperature to a subfreezing temperature. The subfreezing air is then used to cool electronic components and mechanical components within the aircraft. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/705586 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 53/265 (20130101) B01D 53/268 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/10 (20130101) B64D 33/08 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 9/004 (20130101) F25B 9/06 (20130101) F25B 43/003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050233 | Gregoire et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico); Utah State University Space Dynamics Laboratory (North Logan, Utah) |
| ASSIGNEE(S) | Government of the United States, as represented by the Secretary of the Air Force (Washington, District of Columbia); Utah State University Space Dynamics Laboratory (North Logan, Utah) |
| INVENTOR(S) | Maxwell D. Gregoire (Albuquerque, New Mexico); Sean P. Krzyzewski (Albuquerque, New Mexico); Brian L. Kasch (Albuquerque, New Mexico); Charles W. Lewandowski (Albuquerque, New Mexico) |
| ABSTRACT | An accelerometer includes a vacuum chamber to receive one or more pairs of laser beams and a nanoparticle. Each laser beam includes an axis and a focus having three dimensions. The nanoparticle is trapped in an oscillating state in a substantially overlapping three-dimensional foci of the one or more pairs of laser beams. A processor calculates an acceleration of the nanoparticle based on changes in position of the oscillating nanoparticle. At least one photodetector identifies spatial coordinates of the oscillating nanoparticle. The at least one photodetector includes a plurality of photodetectors that are aligned to sense interference between light from a first laser beam and light from the first laser beam that is scattered by the oscillating nanoparticle. The one or more pairs of laser beams may be collinear. The one or more pairs of laser beams may be configured to point at each other. |
| FILED | Tuesday, July 06, 2021 |
| APPL NO | 17/368433 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/093 (20130101) Original (OR) Class Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 17/00 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050265 | Russo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Analog Photonics LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | Analog Photonics LLC (Boston, Massachusetts) |
| INVENTOR(S) | Peter Nicholas Russo (Somerville, Massachusetts); Ehsan Shah Hosseini (Milton, Massachusetts) |
| ABSTRACT | At least one beam of an optical wave is transmitted along a transmission angle toward a target location from a send aperture of a transmitter. A collected optical wave is received at receive apertures of two or more receivers. Each receiver comprises: a receive aperture arranged in proximity to at least one of the send aperture or a receive aperture of a different receiver, an optical phased array within the receive aperture, which receives at least a portion of a collected optical wave arriving at the receive aperture along a respective collection angle, and a detector that provides a signal based on the received portion of the collected optical wave. An estimated distance associated with the collected optical wave is determined based on a combination that includes a respective component corresponding to each of two or more of the signals provided from the detectors of the two or more receivers. |
| FILED | Thursday, November 03, 2022 |
| APPL NO | 17/979931 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/282 (20130101) G01S 17/42 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 3/2676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050688 | Lameres et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MONTANA STATE UNIVERSITY (Bozeman, Montana); RESILIENT COMPUTING, LLC (Bozeman, Montana) |
| ASSIGNEE(S) | MONTANA STATE UNIVERSITY (Bozeman, Montana); RESILIENT COMPUTING, LLC (Bozeman, Montana) |
| INVENTOR(S) | Brock Jerome Lameres (Bozeman, Montana); Christopher Michel Major (Belgrade, Montana); Clemente I. Izurieta (Bozeman, Montana) |
| ABSTRACT | A computer device including a computing engine having a plurality of processor cores configured to simultaneously execute identical sets of processor-executable instructions, where each of the processor cores includes different instruction code assignments, and a malware monitoring and remediation component that detects presence of malware when instruction register values from a predetermined number of processor cores are identical during an instruction cycle. In various embodiments, the computer device may be an “edge” computer deployed in military or other highly-sensitive environments. The computing engine may be implemented using one or more field programmable gate arrays (FPGAs). |
| FILED | Thursday, February 15, 2024 |
| APPL NO | 18/443133 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/566 (20130101) Original (OR) Class G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051215 | Vega-Irizarry |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Rome, New York) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Rome, New York) |
| INVENTOR(S) | Alfredo Vega-Irizarry (Rome, New York) |
| ABSTRACT | A method of detecting starting positions, sizes, and number of records of fields within a bit stream, by formatting the bit stream into a frame using positive logic, then performing decimal conversion of different predetermined field lengths on the framed bit stream, to produce channels. Noise is either removed or amplified from the framed bit stream, and the frame and the channels are input to an image detection module to identify fields within the framed bit stream. |
| FILED | Wednesday, March 27, 2019 |
| APPL NO | 16/365741 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/32 (20170101) Original (OR) Class G06T 2207/20182 (20130101) G06T 2207/20221 (20130101) Coding; Decoding; Code Conversion in General H03M 7/12 (20130101) H03M 7/3086 (20130101) Pictorial Communication, e.g Television H04N 19/126 (20141101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051219 | Krovi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAYTHEON BBN TECHNOLOGIES, CORP. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON BBN TECHNOLOGIES CORP. (Cambridge, Massachusetts) |
| INVENTOR(S) | Hari Kiran Krovi (Lexington, Massachusetts) |
| ABSTRACT | An optical circuit for estimating separation distances between N image sources includes an aperture for receiving N light beams and producing a point spread function specific to a symmetry of the image sources from the plurality of light beams; first optical phase shifters to shift the quantum state modes of (N-1) light beams by |
| FILED | Friday, May 27, 2022 |
| APPL NO | 17/827572 |
| ART UNIT | 2422 — Cable and Television |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 3/08 (20130101) Optical Elements, Systems, or Apparatus G02B 27/10 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) Original (OR) Class G06T 2207/20056 (20130101) G06T 2207/20076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051474 | Lal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Amit Lal (Ithaca, New York); Shubham Jadhav (Ithaca, New York); Ved Gund (Ithaca, New York); Benyamin Davaji (Ithaca, New York); Grace Xing (Ithaca, New York); Debdeep Jena (Ithaca, New York) |
| ABSTRACT | Disclosed are ferroelectric devices including devices for performing a multiplication of analog input signals and resonators. In one aspect, a ferroelectric nanoelectromechanical device includes a first structural beam, a first input electrode disposed on a first top portion of the first structural beam, and an output electrode. The apparatus further includes a first ferroelectric film disposed on a second top portion of the first input electrode, and a first resistive layer disposed on a third top portion of the first ferroelectric film, wherein a first electrode is positioned at a first end of the first resistive layer and a second electrode is positioned at a second end of the first resistive layer. |
| FILED | Tuesday, August 23, 2022 |
| APPL NO | 17/821789 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 23/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051520 | Keesling Contreras et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); California Institute of Technology (Pasadena, California); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Alexander Keesling Contreras (Cambridge, Massachusetts); Hannes Bernien (Somerville, Massachusetts); Sylvain Schwartz (Somerville, Massachusetts); Harry Jay Levine (Cambridge, Massachusetts); Ahmed Omran (Somerville, Massachusetts); Mikhail D. Lukin (Cambridge, Massachusetts); Vladan Vuletic (Cambridge, Massachusetts); Manuel Endres (Padaena, California); Markus Greiner (Belmont, Massachusetts); Hannes Pichler (Tyrol Innsbruck, Austria); Leo Zhou (Somerville, Massachusetts); Shengtao Wang (Somerville, Massachusetts); Soonwon Choi (El Cerrito, California); Donggyu Kim (Arlington, Massachusetts); Alexander S. Zibrov (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods relate to arranging atoms into 1D and/or 2D arrays; exciting the atoms into Rydberg states and evolving the array of atoms, for example, using laser manipulation techniques and high-fidelity laser systems described herein; and observing the resulting final state. In addition, refinements can be made, such as providing high fidelity and coherent control of the assembled array of atoms. Exemplary problems can be solved using the systems and methods for arrangement and control of atoms. |
| FILED | Monday, June 05, 2023 |
| APPL NO | 18/205758 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/33 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) G21K 1/06 (20130101) Original (OR) Class G21K 1/093 (20130101) G21K 2201/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051588 | Robinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Joshua Alexander Robinson (Spring Mills, Pennsylvania); Rafael Vila (Sierra Vista, Arizona) |
| ABSTRACT | The present invention relates to methods for fabricating vertical homogenous and heterogeneous two-dimensional structures, the fabricated vertical two-dimensional structures, and methods of using the same. The methods demonstrated herein produce structures that are free standing and electrically isolated. |
| FILED | Monday, May 03, 2021 |
| APPL NO | 17/246997 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0242 (20130101) H01L 21/0259 (20130101) H01L 21/02376 (20130101) H01L 21/02378 (20130101) H01L 21/02381 (20130101) H01L 21/02565 (20130101) H01L 21/02568 (20130101) Original (OR) Class H01L 21/02612 (20130101) H01L 21/02664 (20130101) H01L 29/24 (20130101) H01L 29/045 (20130101) H01L 29/0665 (20130101) H01L 29/0669 (20130101) H01L 29/778 (20130101) H01L 29/785 (20130101) H01L 29/66795 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051760 | Hart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | SolAero Technologies Corp. (Albuquerque, New Mexico) |
| INVENTOR(S) | John Hart (Albuquerque, New Mexico); Daniel Derkacs (Albuquerque, New Mexico); Zachary Bittner (Albuquerque, New Mexico); Andrew Espenlaub (Albuquerque, New Mexico) |
| ABSTRACT | A multijunction solar cell including an upper first solar subcell having an emitter and base layers forming a photoelectric junction; a second solar subcell disposed under and adjacent to the upper first solar subcell, and having an emitter and base layers forming a photoelectric junction; and a third solar subcell disposed under and adjacent to the second solar subcell and having an emitter and base layers forming a photoelectric junction; wherein at least one of the base and emitter layers of at least a particular solar subcell from among the upper first solar subcell, the second solar subcell, and the third solar subcell has a graded band gap throughout at least a portion of thickness of its active layer adjacent to the photoelectric junction and being in a range of 20 to 300 MeV greater than a band gap in the active layer away from the photoelectric junction. |
| FILED | Thursday, July 13, 2023 |
| APPL NO | 18/221462 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/065 (20130101) H01L 31/0687 (20130101) H01L 31/0693 (20130101) H01L 31/0725 (20130101) H01L 31/0735 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051781 | Gerasopoulos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Konstantinos Gerasopoulos (Odenton, Maryland); Bing Tan (Ann Arbor, Michigan); Priestly T. Shuler (Baltimore, Maryland); Matthew W. Logan (Columbia, Maryland); Sarah K. Adams (Olney, Maryland); Matthew A. Hagedon (Columbia, Maryland) |
| ABSTRACT | A method of manufacturing a three-dimensional electrochemical lithium battery includes forming a first electrode on an underlying layer comprising aerosolizing a first ink formulation comprising a slurry including nanoparticles or microparticles of a first active material and a binder, and depositing the slurry onto the underlying layer to form a first electrode layer. A permeable separator layer is formed on the first electrode by aerosolizing a polymer precursor solution, exposing the aerosolized polymer precursor solution to a first activating radiation source to form partially cured polymer spheres in the aerosolized stream, focusing and directing the aerosolized stream onto a substrate to form the permeable separator layer of the partially cured polymer spheres, and exposing the partially cured polymer spheres on the substrate to a second activating radiation source to fully cure the partially cured polymer spheres. A second electrode is formed on the permeable separator layer by aerosolizing a second ink formulation comprising a slurry including nanoparticles or microparticles of a second active material and a binder, and depositing the slurry onto the permeable separator layer. |
| FILED | Tuesday, July 20, 2021 |
| APPL NO | 17/380527 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/136 (20130101) H01M 4/0419 (20130101) H01M 4/622 (20130101) H01M 4/661 (20130101) H01M 10/058 (20130101) Original (OR) Class H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051857 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Jerry T. W. Kim (Fairfax, Virginia); Behrooz Fakhari (North Potomac, Maryland) |
| ABSTRACT | A transportable, resilient, high frequency system with a compact footprint is provided. The system may include a plurality of antenna elements arranged around a circle. A circular array provides a resilient radiation pattern that does not change based on the number of antennas in the array and is tolerant of errors in antenna placement. The gain of the system may be increased by increasing the number of antenna elements in the array to compensate for reduced efficiency of antenna elements having a radiating element with a length of less than half the wavelength of an operating frequency of the array. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/532342 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/28 (20130101) H01Q 21/20 (20130101) Original (OR) Class H01Q 21/26 (20130101) H01Q 21/293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12052918 | Forrest et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (, None) |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Jongchan Kim (Ann Arbor, Michigan); Siwei Zhang (Ann Arbor, Michigan) |
| ABSTRACT | An organic light emitting device comprises an anode and a cathode, at least one organic layer configured between the anode and the cathode, and at least one two-dimensional emissive layer configured between the anode and the cathode. A method of fabricating an organic light emitting device is also disclosed. |
| FILED | Thursday, June 24, 2021 |
| APPL NO | 17/357485 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Organic electric solid-state devices H10K 50/11 (20230201) H10K 50/15 (20230201) H10K 50/16 (20230201) H10K 85/631 (20230201) H10K 85/654 (20230201) H10K 85/6572 (20230201) Original (OR) Class H10K 85/6574 (20230201) H10K 85/6576 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12048411 | Chichester et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | David L. Chichester (Idaho Falls, Idaho); Alexander K. May (Idaho Falls, Idaho); Kevin P. Carney (Idaho Falls, Idaho) |
| ABSTRACT | A modular particle collection system includes a hollow lower member, a hollow upper member separably attached to the hollow lower member, a collection container separably attached to a longitudinal end of the hollow lower member opposite the hollow upper member, an inlet portion extending radially from the hollow lower member and configured to be fitted to a first portion of a vacuum system, a particulate filter, and an outlet portion extending radially outward from the hollow upper member and configured to be fitted to a second portion of vacuum system. Additional modular particle collection systems and a method of making a modular collection system are also disclosed. |
| FILED | Wednesday, April 20, 2022 |
| APPL NO | 17/659935 |
| ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Domestic Washing or Cleaning; Suction Cleaners in General A47L 5/24 (20130101) A47L 9/104 (20130101) A47L 9/1625 (20130101) A47L 9/1666 (20130101) A47L 9/1683 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048714 | Rozhkova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Elena A. Rozhkova (Lemont, Illinois); Elena Shevchenko (La Grange, Illinois) |
| ABSTRACT | Products and methods for redirecting the pathological biochemical process of accumulation of reduced pyridine nucleotides under deleterious hypoxia conditions toward the reduction of the precursor salt and the biosynthesis of biologically compatible, antioxidant noble metal nanoparticles and the simultaneous restoring of the tissue redox state are provided. The products and methods have application in the treatment of hypoxia and hypoxia-related diseases and disorders. Such products and methods are also useful in organ transplantation and recovery, in screening of anti-hypoxia agents, and in detecting elevated levels of the reducing equivalents of the redox state, for example, NADH, NADPH, GSH, and TrxSH2, in cells, tissues, or organs. |
| FILED | Wednesday, April 08, 2020 |
| APPL NO | 16/843114 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5115 (20130101) A61K 33/242 (20190101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/06 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048892 | Long et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Jeffrey R. Long (Oakland, California); Phillip J. Milner (Ithaca, New York); Rebecca L. Siegelman (Berkeley, California) |
| ABSTRACT | An adsorption material is disclosed that comprises a metal-organic framework and a plurality of ligands. The metal-organic framework comprising a plurality of metal ions. Each respective ligand in the plurality of ligands is amine appended to a respective metal ion in the plurality of metal ions of the metal-organic framework. Each respective ligand in the plurality of ligands comprises a substituted 1,3-propanediamine. The adsorbent has a CO2 adsorption capacity of greater than 2.50 mmol/g at 150 mbar CO2 at 40° C. Moreover, the adsorbent is configured to regenerate at less than 120° C. An example ligand is diamine 2,2-dimethyl-1,3-propanediamine. An example of the metal-organic framework is Mg2(dobpdc), where dobpdc4− is 4,4′-dioxidobiphenyl-3,3′-dicarboxylate. Example applications for the adsorption material are removal of carbon dioxide from flue gas and biogasses. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/937336 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/02 (20130101) Original (OR) Class B01D 2253/204 (20130101) B01D 2257/504 (20130101) B01D 2258/05 (20130101) B01D 2259/4009 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/226 (20130101) B01J 20/3466 (20130101) B01J 20/3491 (20130101) B01J 20/28057 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049597 | Hensley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Jesse Evan Hensley (Arvada, Colorado); Daniel Ruddy (Arvada, Colorado); Joshua A. Schaidle (Arvada, Colorado); Connor Patrick Nash (Lakewood, Colorado) |
| ABSTRACT | The present disclosure relates to a mixture that includes a first portion that includes at least one of a paraffin and/or a naphthene having between 5 carbons and 13 carbons, inclusively, at a first concentration between about 75 wt % and about 99 wt %, and a second portion that includes hydrocarbons having greater than 13 carbons at a second concentration of less than 0.05 wt %. |
| FILED | Monday, November 16, 2020 |
| APPL NO | 17/098785 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 29/7215 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/06 (20130101) Original (OR) Class C10L 10/10 (20130101) C10L 2200/0415 (20130101) C10L 2230/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049654 | Ramakrishnan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Parthasarathi Ramakrishnan (Lucknow, India); Tanmoy Dutta (Berkeley, California); Blake Simmons (San Francisco, California); Seema Singh (Clarksburg, Maryland) |
| ABSTRACT | Methods and compositions are provided for ionic liquid processing of biomass. |
| FILED | Monday, February 01, 2021 |
| APPL NO | 17/164536 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 37/0057 (20130101) Derivatives of Natural Macromolecular Compounds C08H 8/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/02 (20130101) C12P 19/04 (20130101) Original (OR) Class C12P 2201/00 (20130101) C12P 2203/00 (20130101) Saccharides Obtained From Natural Sources or by Hydrolysis of Naturally Occurring Disaccharides, Oligosaccharides or Polysaccharides C13K 1/02 (20130101) C13K 13/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049660 | Hittinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Chris Todd Hittinger (Madison, Wisconsin); Trey Sato (Madison, Wisconsin); Sae-Byuk Lee (Madison, Wisconsin) |
| ABSTRACT | An engineered yeast strain capable of efficient fermentation of xylose to ethanol, and methods of making and using the strain, are provided. |
| FILED | Thursday, November 03, 2022 |
| APPL NO | 18/052410 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) C10L 2200/0469 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/92 (20130101) C12N 9/0093 (20130101) C12N 9/1022 (20130101) C12N 9/1205 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/10 (20130101) Original (OR) Class Enzymes C12Y 117/99 (20130101) C12Y 202/01002 (20130101) C12Y 207/01017 (20130101) C12Y 503/01005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049878 | Simmonds et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Jacob Simmonds (Princeton, New Jersey); Yevgeny Raitses (Princeton, New Jersey) |
| ABSTRACT | Disclosed is a miniaturized plasma propulsion device with minimized surface area of the thruster walls exposed to the plasma and, as a result, reduced plasma-surface interactions including a set of segmented electrodes to facilitate the following improvements compared to relevant existing technologies: 1) control of the plasma flow including focusing of the plasma plume 2) increase of the thrust 2) reduction of inefficiencies associated with the electron cross field current, and 3) mitigation of low frequency oscillations. The electrodes affect all these actions when a DC or modulated voltage is applied to one or all of them with the same or different amplitudes, with the same or different frequencies or phases which are all optimized to realize the best performance through changes in the acceleration and/or ionization regions. In addition, the applied voltage to the main electrodes may also be modulated. |
| FILED | Friday, August 26, 2022 |
| APPL NO | 17/896651 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0068 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050139 | Takayasu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Makoto Takayasu (Lexington, Massachusetts) |
| ABSTRACT | The present system and method allow for the detection and diagnosis of abrupt changes of a device operating condition using a sensor array disposed in the coolant where the device is located. The purpose of the sensor array is to identify, in real time, abrupt changes quickly and detect the location of the incident. It may be used, for example, for quench detection of superconducting cables and magnets. This system and method are not only limited to use with superconducting conductors such as magnets, power transmission cables, SMES, MRI, motors and generators, but could also be used for any electric devices disposed in liquid or gas. It can also be used for a liquid level meter. Further, this system and method are not limited to low temperature devices, but may also be used in room temperature or elevated higher temperature devices disposed in gas and/or liquid. |
| FILED | Tuesday, October 20, 2020 |
| APPL NO | 17/075083 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 5/04 (20130101) G01K 5/28 (20130101) G01K 13/006 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050221 | Cahill |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | John F. Cahill (Knoxville, Tennessee) |
| ABSTRACT | A method for analyzing single cells by mass spectrometry includes the steps of providing a plurality of cells in a liquid medium and placing the cells and liquid medium in a single cell isolation and ejection system. Liquid medium containing a single cell is released from the single cell isolation and ejection system. The liquid medium and single cell are captured in a capture probe containing a flowing capture probe solvent. The cell is lysed by a lysis inducer in the capture probe to disperse single cell components into the medium. The lysed single cell components are transported to a mass spectrometer, where the lysed single cell components entering the mass spectrometer are spatially and temporally separated from any dispersed components of another single cell from the sample entering the mass spectrometer. Mass spectrometry is conducted on the lysed single-cell components. A system for analyzing single cells by mass spectrometry is also disclosed. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/111336 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/7233 (20130101) G01N 33/6848 (20130101) Original (OR) Class G01N 2560/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050291 | Jarrell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Joshua Jarrell (Livermore, California); Nerine Cherepy (Piedmont, California); John Winter Murphy (Mountain House, California); Rebecca J. Nikolic (Oakland, California); Erik Lars Swanberg, Jr. (Livermore, California) |
| ABSTRACT | A product includes a transparent scintillator material, a beta emitter material having an end-point energy of greater than 225 kiloelectron volts (keV), and a photovoltaic portion configured to convert light emitted by the scintillator material to electricity. A thickness the scintillator material is sufficient to protect the photovoltaic portion from significant radiation damage. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/863164 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/2002 (20130101) G01T 1/2023 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/115 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050389 | Strand et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Michael T. Strand (Boulder, Colorado); Christopher Barile (Reno, Nevada); Tyler S. Hernandez (Boulder, Colorado); Andrew L Yeang (Boulder, Colorado); Michael D. McGehee (Boulder, Colorado) |
| ABSTRACT | Dynamic windows with adjustable tint give users greater control over flow of light and heat. Reversible metal electrodeposition dynamic windows include (i) a transparent or translucent conductive electrode; (ii) an electrolyte solution in contact with the electrode, the electrolyte solution comprising metal cations that are reversibly electrodeposited onto the transparent electrode upon application of a cathodic potential; and (iii) a counter electrode. The electrolyte solution advantageously includes a small amount of an additive (e.g., an inhibitor, an accelerator, a leveler, or an organic or inorganic molecule that similarly serves to enhance the surface morphology of the metal cations during reversible metal electrodeposition onto the transparent electrode). Such enhancement of surface morphology during the reversible electrodeposition of the metal tinting layer over the electrode enhances one or more of color neutrality, transmittance characteristics of visible wavelengths (e.g., ability to achieve a near 0% transmission privacy state), infrared reflectance, or switching speed. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/506170 |
| ART UNIT | 2871 — Optics |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 17/10036 (20130101) B32B 17/10513 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 9/00 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 3/6722 (20130101) E06B 9/24 (20130101) E06B 2009/2464 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/155 (20130101) G02F 1/1506 (20130101) Original (OR) Class G02F 1/13439 (20130101) G02F 2001/164 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051538 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Particle Beam Lasers, Inc. (Waxahachie, Texas); Brookhaven Science Associates, LLC (Upton, New York) |
| ASSIGNEE(S) | Particle Beam Lasers, Inc. (Waxahachie, Texas); Brookhaven Science Associates, LLC (Upton, New York) |
| INVENTOR(S) | Ramesh Gupta (Shoreham, New York); Erich Willen (Westminster, Maryland); Bob Weggel (Reading, Massachusetts) |
| ABSTRACT | A solenoid-magnet system and method for producing high-magnetic-fields, including a substantially radially-open-region located in the axially central region of the solenoid-magnet to allow target placement, particle beam transport and other uses, a substantially axially-open-region located in the radially central region of the solenoid-magnet to allow target placement, particle beam transport and other uses, axially-inward-low-temperature-superconducting-coils and axially-outward-low-temperature-superconducting-coils comprised of low-temperature-superconducting-wire located in radially-outward-regions to generate high magnetic-fields, axially-inward-high-temperature-superconducting-coils and axially-outward-high-temperature-superconducting-coils comprised of high-temperature-superconducting-tape located in radially-inward-regions to generate even higher magnetic-fields, and support-structures to support the coils against large Lorentz-forces. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 17/479025 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20008 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/147 (20130101) H01F 6/06 (20130101) Original (OR) Class H01F 41/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051539 | Kashikhin |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| INVENTOR(S) | Vadim V. Kashikhin (North Aurora, Illinois) |
| ABSTRACT | A Conductor on Molded Barrel (COMB) magnet assembly optimized for High Temperature Superconducting (HTS) materials. The magnet assembly comprises a magnetic coil(s) carried by a conductor support structure and configured in cosine-theta geometry. Created using additive manufacturing, the conductor support structure features a continuous cable channel that fittedly carries and positions elongated straight portion(s) of the magnetic coil(s) parallel to a magnetic axis. The conductor support structure may be cylindrically shaped and longitudinally bored, with the continuous cable channel comprising an outer channel portion (distal on the cylinder) and an inner channel portion (proximal on the cylinder). A transition hole that joins the outer channel portion and the inner channel portion allows a single magnetic coil to be wound along both the outer and inner surfaces of the conductor support structure. The conductor support structure may be fabricated as longitudinally-symmetrical halves, and secured for operation using azimuthal and/or midplane shims. |
| FILED | Wednesday, April 19, 2023 |
| APPL NO | 18/136590 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/00 (20210101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/342 (20151001) B23K 26/354 (20151001) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/147 (20130101) H01F 5/02 (20130101) H01F 6/06 (20130101) Original (OR) Class H01F 41/048 (20130101) H01F 41/082 (20160101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051824 | Visco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California) |
| ABSTRACT | Manufacturing methods for making a substantially rectangular and flat glass preform for manufacturing a Li ion conducting glass separator can involve drawing the preform to a thin sheet and may involve one or more of slumping, rolling or casting the glass within a frame that defines a space filling region and therewith the shape and size of the preform. The thickness of the rectangular flat preform so formed may be about 2 mm or less. The frame may be slotted having a back surface and widthwise wall portion that define the height and width of the space filling region. The flat backing surface and surfaces of the widthwise wall portions are defined may be coated by a material that is inert in direct contact with the heated glass material, such as gold. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/302491 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Manufacture, Shaping, or Supplementary Processes C03B 15/02 (20130101) C03B 19/02 (20130101) C03B 2215/44 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 17/22 (20130101) C03C 2217/255 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 50/403 (20210101) Original (OR) Class H01M 50/437 (20210101) H01M 50/449 (20210101) H01M 50/466 (20210101) H01M 50/469 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051906 | Weaver et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Alubquerque, New Mexico); Michigan Technological University (Houghton, Michigan) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Michigan Technological University (Houghton, Michigan) |
| INVENTOR(S) | Wayne W. Weaver (Hancock, Michigan); David G. Wilson (Tijeras, New Mexico); Rush D. Robinett, III (Tijeras, New Mexico) |
| ABSTRACT | A DC bus collection system for a wind farm reduces the overall required number of converters and minimizes the energy storage system requirements. The DC bus collection system implements a power phasing control method between wind turbines that filters the variations and improves power quality. The phasing control method takes advantage of a novel power packet network concept with nonlinear power flow control design techniques that guarantees both stable and enhanced dynamic performance. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/684665 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Wind Motors F03D 9/11 (20160501) F03D 9/257 (20170201) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/381 (20130101) Original (OR) Class H02J 2300/28 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12052877 | Forrest et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan); Yongxi Li (Ann Arbor, Michigan) |
| ABSTRACT | A method of making a photovoltaic cell comprises the steps of providing a substrate in a vacuum, depositing an anode over the substrate, depositing a first heterojunction layer over the anode layer, depositing a second heterojunction layer over the first heterojunction layer, depositing a cathode over the second heterojunction layer, and releasing the vacuum. A photovoltaic cell is also described. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/038718 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Organic electric solid-state devices H10K 30/30 (20230201) Original (OR) Class H10K 71/164 (20230201) H10K 85/211 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12048450 | Seymour et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brigham Young University (Provo, Utah) |
| ASSIGNEE(S) | Brigham Young University (Provo, Utah) |
| INVENTOR(S) | Kendall H. Seymour (Springville, Utah); Jacob Sheffield (Provo, Utah); Lance Hyatt (Provo, Utah); Scott Cunnington (Provo, Utah); Spencer P. Magleby (Provo, Utah); Larry L. Howell (Orem, Utah) |
| ABSTRACT | A hollow rod developable actuator tool including a first link comprising an outer cylinder, a second link comprising a first tool member pivotably connected to the first link at a first joint mounted in a first cavity in the wall of the outer cylinder, a third link comprising a second tool member pivotably connected to the first tool member at a second link, and a fourth link comprising an inner cylinder to which the second tool member is also pivotably connected at a third link mounted in a second cavity in the wall of the inner cylinder. When the inner cylinder of the fourth link is rotated in relation to the outer cylinder of the first link the actuator tool transitions from a first state where the tool is closed to a second state where the tool is open. |
| FILED | Thursday, June 01, 2023 |
| APPL NO | 18/204554 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/22031 (20130101) A61B 17/32002 (20130101) Original (OR) Class A61B 17/320016 (20130101) A61B 17/320783 (20130101) A61B 2017/32004 (20130101) A61B 2017/320024 (20130101) A61B 2017/320028 (20130101) A61B 2017/320032 (20130101) A61B 2017/320078 (20170801) A61B 2017/320082 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12048910 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Qi Hua Fan (Okemos, Michigan); Martin E. Toomajian (Brighton, Michigan); Thomas Schuelke (Pinckney, Michigan) |
| ABSTRACT | A vertically oriented plasma reactor is provided. In another aspect, a plasma reactor includes a vertically elongated vacuum chamber, a wall internally projecting within a middle section of the housing, magnets, electrodes and a radio frequency source. A further aspect employs a workpiece-entry port and an opposite workpiece material-exit port, with one located adjacent a top end and the other adjacent a bottom end of a vertically elongated reactor housing or vacuum chamber. Yet another aspect employs a moving or falling-bed plasma reactor for use in activating biochar material. |
| FILED | Thursday, July 11, 2019 |
| APPL NO | 17/258881 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/006 (20130101) B01J 19/088 (20130101) Original (OR) Class B01J 20/20 (20130101) B01J 20/3416 (20130101) B01J 2219/0894 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/366 (20170801) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/466 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049532 | Do et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Loi H. Do (Manvel, Texas); Thi V. Tran (Houston, Texas) |
| ABSTRACT | This invention relates to nickel catalysts with alkali ions for homopolymerization and copolymerization. |
| FILED | Tuesday, November 08, 2022 |
| APPL NO | 17/982767 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/06 (20130101) C08F 4/7098 (20130101) Original (OR) Class C08F 210/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050182 | Hemler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Sarah L. Hemler (Geneva, Switzerland); Kurt E. Beschorner (Pittsburgh, Pennsylvania) |
| ABSTRACT | A system for monitoring the tread of a shoe includes a frame member, a waveguide structured to support the shoe when an outer sole of shoe is in contact with a surface of the waveguide, a light source structured to provide light within an edge of the waveguide such that the light will be internally reflected within the waveguide, and an imaging device structured and configured to generate an image of the outer sole of the shoe when the outer sole of shoe is in contact with the waveguide and the light is being provided within the waveguide. The system also includes a controller structured and configured to: (i) receive image data based on the image of the outer sole; (ii) determine from the image data a largest worn region size for the shoe; and (iii) determine a slip risk for the shoe based on the largest worn region size. |
| FILED | Friday, December 02, 2022 |
| APPL NO | 18/061215 |
| ART UNIT | 2481 — Recording and Compression |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/8851 (20130101) Original (OR) Class G01N 2021/8874 (20130101) Optical Elements, Systems, or Apparatus G02B 6/42 (20130101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) G06T 7/62 (20170101) Pictorial Communication, e.g Television H04N 23/56 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050215 | Takayama et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Shuichi Takayama (Ann Arbor, Michigan); Cameron Louttit (Ann Arbor, Michigan); James J. Moon (Ann Arbor, Michigan); Taisuke Kojima (Ann Arbor, Michigan); Priyan Weerappuli (Ann Arbor, Michigan) |
| ABSTRACT | Provided herein are macromolecular structures comprising charged macromolecules. In particular, provided herein are synthetic neutrophil extracellular traps and uses thereof. |
| FILED | Wednesday, November 16, 2016 |
| APPL NO | 15/776346 |
| ART UNIT | 1675 — Printing/Measuring and Testing |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/10 (20130101) A01N 57/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/089 (20200101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/544 (20130101) Original (OR) Class G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12050967 | Calderbank et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Arthur Robert Calderbank (Durham, North Carolina); Jingzhen Hu (Durham, North Carolina); Qingzhong Liang (Durham, North Carolina) |
| ABSTRACT | Technologies for addressing coherent noise in a quantum system are disclosed. To passively correct for errors in measurement caused by coherent noise, the quantum system implements an error correction code such that the error correction code effectively reduces the coherent noise to act as an identity operator in a protected subspace of a Hilbert vector space. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673586 |
| ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/70 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051028 | Gurney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents acting for and on behalf of Northern Arizona University (Flagstaff, Arizona); Arizona Board of Regents acting for and on behalf of Arizona State University (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents Acting For and on Behalf of North Arizona University (Tempe, Arizona); Arizona State University (Flagstaff, Arizona) |
| INVENTOR(S) | Kevin Gurney (Flagstaff, Arizona); Deborah Huntzinger (Flagstaff, Arizona); Taha Moiz (Tempe, Arizona); Nathan Parker (Tempe, Arizona); Richard Rushforth (Flagstaff, Arizona); Benjamin L. Ruddell (Flagstaff, Arizona) |
| ABSTRACT | Implementations of a method of modeling a flow of resources may include generating a stage resource database when the resources reach one or more stages from one or more supply nodes. The method may also include using a mass balance module to maintain an outflow less than or equal to a supply at the one or more supply nodes and an inflow greater than or equal to demand at the one or more stages. The method may include enforcing movement of resources to or from one or more supply nodes of the supply chain to the one or more stages. The method may include using a non-negativity constraint module to maintain a non-negative amount to be transported. The method may also include using a flow generation module and one or more constraint thresholds to report to a user the flow of the resources using one or more computer interfaces. |
| FILED | Friday, November 25, 2022 |
| APPL NO | 18/058848 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/08 (20130101) Original (OR) Class G06Q 10/047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051219 | Krovi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RAYTHEON BBN TECHNOLOGIES, CORP. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON BBN TECHNOLOGIES CORP. (Cambridge, Massachusetts) |
| INVENTOR(S) | Hari Kiran Krovi (Lexington, Massachusetts) |
| ABSTRACT | An optical circuit for estimating separation distances between N image sources includes an aperture for receiving N light beams and producing a point spread function specific to a symmetry of the image sources from the plurality of light beams; first optical phase shifters to shift the quantum state modes of (N-1) light beams by |
| FILED | Friday, May 27, 2022 |
| APPL NO | 17/827572 |
| ART UNIT | 2422 — Cable and Television |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 3/08 (20130101) Optical Elements, Systems, or Apparatus G02B 27/10 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) Original (OR) Class G06T 2207/20056 (20130101) G06T 2207/20076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051520 | Keesling Contreras et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); California Institute of Technology (Pasadena, California); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Alexander Keesling Contreras (Cambridge, Massachusetts); Hannes Bernien (Somerville, Massachusetts); Sylvain Schwartz (Somerville, Massachusetts); Harry Jay Levine (Cambridge, Massachusetts); Ahmed Omran (Somerville, Massachusetts); Mikhail D. Lukin (Cambridge, Massachusetts); Vladan Vuletic (Cambridge, Massachusetts); Manuel Endres (Padaena, California); Markus Greiner (Belmont, Massachusetts); Hannes Pichler (Tyrol Innsbruck, Austria); Leo Zhou (Somerville, Massachusetts); Shengtao Wang (Somerville, Massachusetts); Soonwon Choi (El Cerrito, California); Donggyu Kim (Arlington, Massachusetts); Alexander S. Zibrov (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods relate to arranging atoms into 1D and/or 2D arrays; exciting the atoms into Rydberg states and evolving the array of atoms, for example, using laser manipulation techniques and high-fidelity laser systems described herein; and observing the resulting final state. In addition, refinements can be made, such as providing high fidelity and coherent control of the assembled array of atoms. Exemplary problems can be solved using the systems and methods for arrangement and control of atoms. |
| FILED | Monday, June 05, 2023 |
| APPL NO | 18/205758 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/33 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) G21K 1/06 (20130101) Original (OR) Class G21K 1/093 (20130101) G21K 2201/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051588 | Robinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Joshua Alexander Robinson (Spring Mills, Pennsylvania); Rafael Vila (Sierra Vista, Arizona) |
| ABSTRACT | The present invention relates to methods for fabricating vertical homogenous and heterogeneous two-dimensional structures, the fabricated vertical two-dimensional structures, and methods of using the same. The methods demonstrated herein produce structures that are free standing and electrically isolated. |
| FILED | Monday, May 03, 2021 |
| APPL NO | 17/246997 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0242 (20130101) H01L 21/0259 (20130101) H01L 21/02376 (20130101) H01L 21/02378 (20130101) H01L 21/02381 (20130101) H01L 21/02565 (20130101) H01L 21/02568 (20130101) Original (OR) Class H01L 21/02612 (20130101) H01L 21/02664 (20130101) H01L 29/24 (20130101) H01L 29/045 (20130101) H01L 29/0665 (20130101) H01L 29/0669 (20130101) H01L 29/778 (20130101) H01L 29/785 (20130101) H01L 29/66795 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051795 | Watkins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | James J. Watkins (South Hadley, Massachusetts); Wenhao Li (Sunderland, Massachusetts) |
| ABSTRACT | Various embodiments disclosed relate to novel methods of fabricating 3-D Li ion batteries using direct nanoimprint lithography. The present invention includes methods of fabricating high surface area electrodes, including imprint patterning of high aspect ratio parallel grating style electrodes. The method includes coating a substrate with an ink containing nanoparticles and subsequently annealing the ink into a desired pattern. |
| FILED | Wednesday, June 22, 2022 |
| APPL NO | 17/808229 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/366 (20130101) H01M 4/0404 (20130101) H01M 4/0433 (20130101) Original (OR) Class H01M 4/0471 (20130101) H01M 4/505 (20130101) H01M 4/622 (20130101) H01M 4/1391 (20130101) H01M 10/058 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
12051801 — Lithium and zinc ion battery containing polyethylene oxide and acetate layered electrodes
| US 12051801 | Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AEsir Technologies, Inc. (Bozeman, Montana) |
| ASSIGNEE(S) | AEsir Technologies, Inc. (Bozeman, Montana) |
| INVENTOR(S) | Hannah S. Smith (Bozeman, Montana); Melissa D. McIntyre (Butte, Montana); Adam Weisenstein (Bozeman, Montana) |
| ABSTRACT | Layers including acetate doped polyethylene oxide adhered to the face of zinc negative electrodes or lithium intercalation positive electrodes are contemplated herein. These layers may penetrate into the surface of the electrode, partially filling the void space. A secondary battery may include some of the electrodes contemplated herein along with corresponding separator systems. |
| FILED | Friday, September 15, 2023 |
| APPL NO | 18/468283 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/62 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 10/38 (20130101) H01M 10/4235 (20130101) H01M 2004/027 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 12048309 | Gomelsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Wyoming (Laramie, Wyoming) |
| ASSIGNEE(S) | University of Wyoming (Laramie, Wyoming) |
| INVENTOR(S) | Mark Gomelsky (Laramie, Wyoming); Ahmed Elbakush (Tripoli, Libya) |
| ABSTRACT | Methods and compositions for inhibiting or dispersing biofilms produced by Listeria monocytogenes on plant matter are described. Embodiments include using formulations comprising active chemical constituents and aqueous extracts or sap from certain trees. Methods of using and producing aqueous formulations derived from hickory and maple wood are provided. Formulations and methods are provided for preventing and dispersing exopolysaccharide-rich listerial biofilms. |
| FILED | Monday, August 01, 2022 |
| APPL NO | 17/878517 |
| ART UNIT | 1793 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 7/16 (20130101) Original (OR) Class A23B 7/154 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 3/3463 (20130101) A23L 3/3508 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12049026 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | NUtech Ventures (Lincoln, Nebraska) |
| INVENTOR(S) | Yiqi Yang (Lincoln, Nebraska); Bingnan Mu (Lincoln, Nebraska) |
| ABSTRACT | A method for preparing keratin-based composites includes mixing polysaccharide nanoparticles and a keratin solution to form a nanoparticle-keratin solution; and solvent casting the nanoparticle-keratin solution to form the keratin-based composites. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/478279 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 39/003 (20130101) Original (OR) Class B29C 39/38 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2005/00 (20130101) B29K 2089/00 (20130101) B29K 2105/251 (20130101) B29K 2995/0097 (20130101) Polysaccharides; Derivatives Thereof C08B 37/003 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/37 (20130101) C08K 2201/005 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 89/04 (20130101) C08L 2201/54 (20130101) C08L 2203/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12050343 | Bhethanabotla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Venkat Rama Bhethanabotla (Tampa, Florida); Thomas M. Weller (Corvallis, Oregon); Roger Brandon Tipton (Wesley Chapel, Florida); John Townsend Bentley (Tampa, Florida); Eduardo Antonio Rojas (Port Orange, Florida) |
| ABSTRACT | A novel polymer optical waveguide and method of manufacturing is presented herein. A digitally manufactured process is described which utilizes a micro-dispensed UV optical adhesive as the contour guiding cladding, a fused deposition modeling technology for creating a core, and a subtractive laser process to finish the two ends of the optical interconnect. The optical waveguide can be printed directly on a circuit board in some embodiments. Alternatively, using a slightly modified process including a step to bond the optical fiber to the substrate, the optical interconnect can be manufactured on a flexible substrate. |
| FILED | Tuesday, November 08, 2022 |
| APPL NO | 17/982907 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2101/12 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Optical Elements, Systems, or Apparatus G02B 6/138 (20130101) G02B 6/1221 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051516 | Sen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GeoPlasma, LLC (Huntsville, Alabama) |
| ASSIGNEE(S) | GeoPlasma, LLC (Huntsville, Alabama) |
| INVENTOR(S) | Subhayu Sen (Madison, Alabama); J. Scott O'Dell (Arab, Alabama) |
| ABSTRACT | Radiation shielding performs a range of functions determined by the type and number of layers of materials used, thickness, weight, and structural support afforded by the radiation shielding. A radiation shield laminate stack may be constructed consisting of a plurality of layers of ultra-high molecular weight (UHMW) polyethylene, polyethylene film, and carbon fiber, which is held together with an epoxy. The carbon fiber lay may be coated with nanoparticles of Boron (B) or Boron Nitride (BN), Boron Oxide (B2O3) or Boron Carbide (B4C) or a combination thereof to increase the shielding properties of the laminate stack. The radiation shield is lighter than aluminum, structurally sound, and thus may be used in the space environment to effectively block Galactic Cosmic Rays, atomic oxygen and UV radiation. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 17/462601 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/48 (20130101) B29C 70/342 (20130101) B29C 70/443 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) B29K 2623/06 (20130101) B29K 2707/04 (20130101) B29K 2713/02 (20130101) B29K 2995/0055 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/024 (20130101) B32B 27/12 (20130101) B32B 27/32 (20130101) B32B 2255/02 (20130101) B32B 2255/20 (20130101) B32B 2260/023 (20130101) B32B 2260/046 (20130101) B32B 2262/106 (20130101) B32B 2307/212 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/128 (20130101) C08J 5/243 (20210501) C08J 5/248 (20210501) C08J 2323/06 (20130101) C08J 2463/00 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 10/06 (20130101) D06M 10/025 (20130101) D06M 11/58 (20130101) D06M 11/74 (20130101) D06M 11/82 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 1/12 (20130101) Original (OR) Class G21F 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 12051177 | Breish et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DIGITAL CHECK CORP. (Northbrook, Illinois) |
| ASSIGNEE(S) | DIGITAL CHECK CORP. (Northbrook, Illinois) |
| INVENTOR(S) | Kurt Breish (Garden Valley, Idaho); Torin Ford (Boise, Idaho) |
| ABSTRACT | Image stitching from multiple line scanners may be provided by selecting, at a plurality of times while progressing a film roll from a supply reel to a take-up reel, overlap areas on the film roll between first and second field of views of a first and second line scan sensors that read first and second data streams from the film roll; calculating, at each time, a difference measure between the first and second data streams in a current overlap area for a current time; adjusting, based on the difference measure, a size or a position of the overlap area for use at a subsequent time as the film roll progresses such that the current overlap area has a first number of pixels and a subsequent overlap area has a second number of pixels; and blending the first and second data streams at the current time at the current overlap area. |
| FILED | Monday, May 15, 2023 |
| APPL NO | 18/197551 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) Original (OR) Class G06T 7/0002 (20130101) G06T 7/97 (20170101) G06T 2207/10008 (20130101) G06T 2207/20221 (20130101) G06T 2207/20224 (20130101) Pictorial Communication, e.g Television H04N 1/00665 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051857 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Jerry T. W. Kim (Fairfax, Virginia); Behrooz Fakhari (North Potomac, Maryland) |
| ABSTRACT | A transportable, resilient, high frequency system with a compact footprint is provided. The system may include a plurality of antenna elements arranged around a circle. A circular array provides a resilient radiation pattern that does not change based on the number of antennas in the array and is tolerant of errors in antenna placement. The gain of the system may be increased by increasing the number of antenna elements in the array to compensate for reduced efficiency of antenna elements having a radiating element with a length of less than half the wavelength of an operating frequency of the array. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/532342 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/28 (20130101) H01Q 21/20 (20130101) Original (OR) Class H01Q 21/26 (20130101) H01Q 21/293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 12051031 | Klausner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Peter Klausner (Scottsdale, Arizona); Robert E. Dixon, Jr. (Haymarket, Virginia) |
| ABSTRACT | Systems described herein for controlling, requesting, and coordinating the creation and generation of labels can be a label broker, providing a centralized location for storing label information created by various entities, and managing the requests for generation of physical labels coming from various sources and entities. |
| FILED | Tuesday, December 28, 2021 |
| APPL NO | 17/646194 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/08 (20130101) G06Q 10/083 (20130101) Original (OR) Class Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus G07B 17/00016 (20130101) G07B 17/00314 (20130101) G07B 17/00508 (20130101) G07B 2017/00064 (20130101) G07B 2017/00161 (20130101) G07B 2017/00258 (20130101) G07B 2017/00588 (20130101) Coin-freed or Like Apparatus G07F 17/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12051034 | Dearing |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Stephen M. Dearing (Herndon, Virginia) |
| ABSTRACT | A system and method for accurately tracking the delivery of items in an item distribution network using a purpose built confidence event recorder. An item sorter sorts items for delivery based upon route information and preferences for the delivery. Items are tracked while out for delivery through the use of confidence data recorded by a confidence event recorder carried by an item carrier. The confidence data recorder can that can record GPS and time data, as well as scan barcodes, such as a barcode on an item to be delivered. Confidence data can be used to accurately record when and where item carriers deliver items. The system determines if an actual delivery occurred by comparing the confidence data to previously gathered confidence data. An expected delivery window generation system can be used to generate expected delivery windows for the delivery of new items based on the confidence data recorded. |
| FILED | Tuesday, May 31, 2022 |
| APPL NO | 17/804670 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 16/29 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0833 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 12050162 | Adolphson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INNOVAPREP LLC (Drexel, Missouri) |
| ASSIGNEE(S) | InnovaPrep, LLC (Drexel, Missouri) |
| INVENTOR(S) | Alec D. Adolphson (Raymore, Missouri); Andrew E. Page (Smithton, Missouri); John D. Birkenholz (Kansas City, Missouri); David Goad (Stillwater, Oklahoma) |
| ABSTRACT | Devices, systems and methods are disclosed which relate to a prefiltration device that can be used with the concentrating pipette instruments and other devices which draw a sample in through one opening and dispense a concentrated or eluted sample out through the same opening. The device allows the sample to be passed through a prefilter when entering the opening and then bypassed the prefilter when being dispensed through the same opening. |
| FILED | Friday, April 22, 2022 |
| APPL NO | 17/726625 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) B01L 2300/0681 (20130101) B01L 2300/0832 (20130101) B01L 2400/0683 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 12049306 | Ramakrishnan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Cincinnati, Ohio) |
| INVENTOR(S) | Kishore Ramakrishnan (Rexford, New York); Valeria Andreoli (Watertown, Massachusetts); Daniel L. Tweedt (West Chester, Ohio) |
| ABSTRACT | A blade for an open rotor includes a pressure side and a suction side, the pressure side and the suction side intersecting at a leading edge and a trailing edge, wherein for at least 30% of a span of the blade, the meanline of the airfoil section is shaped such that a relative curvature parameter is greater than 1.2 in a first region, less than 0.75 in a second region, and greater than 0.9 in a third region, wherein the relative curvature parameter of a region is defined by Δζn/Δζtot/Δ(x/c)n wherein ζ corresponds to the inverse tangent of the slope of a meanline curve, subscript n indicates the region, and x/c is a chordwise location normalized by the chord and wherein the first region comprises at least x/c=0.0 to 0.15 and the third region comprises at least x/c=0.80 to 1.0. |
| FILED | Wednesday, February 15, 2023 |
| APPL NO | 18/169757 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/467 (20130101) B64C 27/473 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 12049486 | Pisegna et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); The United States Government Represented by The Department Of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); THE UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Joseph R. Pisegna (Santa Monica, California); Patrizia M. Germano (Santa Monica, California); John P. Vu (Los Angeles, California) |
| ABSTRACT | In certain embodiments novel PAC1 receptor agonists are provided wherein the agonists comprise a targeting sequence that binds to the PAC1 receptor and said targeting sequence is attached to an amino acid sequence comprising a fragment of the maxadilan amino acid sequence, wherein the targeting sequence comprises a full-length 38 amino acid PACAP peptide or an N-terminus fragment thereof containing the amino acid sequence HSDGIF, wherein said targeting sequence optionally comprises an amino acid insertion between residues 11 and 12 of said PACAP peptide or fragment thereof; and the fragment of the maxadilan amino acid sequence comprises a fragment of the maxadilan sequence effective to activate PAC1 signaling. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/510090 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4985 (20130101) A61K 38/00 (20130101) A61K 38/2278 (20130101) A61K 47/60 (20170801) A61K 47/61 (20170801) A61K 47/65 (20170801) Peptides C07K 14/43577 (20130101) C07K 14/57563 (20130101) Original (OR) Class C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 12050162 | Adolphson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INNOVAPREP LLC (Drexel, Missouri) |
| ASSIGNEE(S) | InnovaPrep, LLC (Drexel, Missouri) |
| INVENTOR(S) | Alec D. Adolphson (Raymore, Missouri); Andrew E. Page (Smithton, Missouri); John D. Birkenholz (Kansas City, Missouri); David Goad (Stillwater, Oklahoma) |
| ABSTRACT | Devices, systems and methods are disclosed which relate to a prefiltration device that can be used with the concentrating pipette instruments and other devices which draw a sample in through one opening and dispense a concentrated or eluted sample out through the same opening. The device allows the sample to be passed through a prefilter when entering the opening and then bypassed the prefilter when being dispensed through the same opening. |
| FILED | Friday, April 22, 2022 |
| APPL NO | 17/726625 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) B01L 2300/0681 (20130101) B01L 2300/0832 (20130101) B01L 2400/0683 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, July 30, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240730.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page