FedInvent™ Patents
Patent Details for Tuesday, August 06, 2024
This page was updated on Tuesday, August 06, 2024 at 05:42 AM GMT
Department of Health and Human Services (HHS)
| US 12053164 | Leith et al. |
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| FUNDED BY |
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| APPLICANT(S) | Access Sensor Technologies LLC (Fort Collins, Colorado); Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado); Access Sensor Technologies LLC (Fort Collins, Colorado) |
| INVENTOR(S) | David Leith (Chapel Hill, North Carolina); John Volckens (Fort Collins, Colorado); Christian L'Orange (Fort Collins, Colorado); Daniel D. Miller-Lionberg (Denver, Colorado) |
| ABSTRACT | A portable sampler, the sampler including a sampler assembly having a housing that includes a receiver defined therein for interchangeably receiving a number of removable inlet assemblies, the removable inlet assemblies including a respirable inlet assembly and a thoracic inlet assembly. The respirable inlet assembly includes a hybrid cyclone assembly, the hybrid cyclone assembly including an impaction stage and a cyclone in series. The thoracic inlet assembly includes an inlet slot configured to function as a size-selective inlet. Another thoracic inlet assembly includes a housing having a number of openings configured to receive a sample airflow; an inlet insert through which an inlet aperture is defined; a prequalification chamber defined between a lower surface of the housing and an upper surface of the inlet insert; and a protrusion extending downward from the lower surface of the housing into the inlet aperture of the inlet insert to from an inlet slot. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/127520 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/00 (20130101) Original (OR) Class A61B 2010/0087 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2208 (20130101) G01N 1/2211 (20130101) G01N 1/2273 (20130101) G01N 15/0255 (20130101) G01N 2015/0261 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053268 | Grissom et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | William A. Grissom (Nashville, Tennessee); Charles F. Caskey (Nashville, Tennessee) |
| ABSTRACT | A system and method of magnetic particle imaging (MPI) are disclosed. The system and method use ultrasound to drive magnetic particles (such as nanoparticles) through a magnetic field gradient to generate a signal and map the magnetic particles' distribution or concentration. |
| FILED | Monday, October 23, 2023 |
| APPL NO | 18/382643 |
| ART UNIT | 3798 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/0515 (20130101) Original (OR) Class A61B 8/485 (20130101) A61B 2562/0223 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/8906 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053288 | {hacek over (S)}arlija et al. |
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| FUNDED BY |
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| APPLICANT(S) | NeuroGeneces Inc. (Santa Fe, New Mexico) |
| ASSIGNEE(S) | NeuroGeneces Inc. (Santa Fe, New Mexico) |
| INVENTOR(S) | Marko {hacek over (S)}arlija (Zagreb, Croatia); Michael Kenneth Comerford, III (Santa Fe, New Mexico); Karen Crow (Santa Fe, New Mexico) |
| ABSTRACT | Some systems, devices and methods detailed herein provide a system for use in determining metrics of a subject. The system can provide, as an output, a function-metric value determined based on a defined relationship between physiological measures and a chronological age. |
| FILED | Thursday, April 20, 2023 |
| APPL NO | 18/137250 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/31 (20210101) A61B 5/72 (20130101) A61B 5/0205 (20130101) A61B 5/291 (20210101) A61B 5/369 (20210101) A61B 5/374 (20210101) A61B 5/377 (20210101) Original (OR) Class A61B 5/384 (20210101) A61B 5/725 (20130101) A61B 5/02416 (20130101) A61B 5/4806 (20130101) A61B 5/4809 (20130101) A61B 5/4812 (20130101) A61B 5/4815 (20130101) A61B 5/7235 (20130101) A61B 5/7267 (20130101) A61B 5/7275 (20130101) Electric Digital Data Processing G06F 3/015 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) G06N 3/06 (20130101) G06N 3/08 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053460 | Xie et al. |
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| FUNDED BY |
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| APPLICANT(S) | Meharry Medical College (Nashville, Tennessee); Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Meharry Medical College (Nashville, Tennessee); Duke University (Durham, North Carolina) |
| INVENTOR(S) | Hua Xie (Nashville, Tennessee); Chin-Ho Chen (Durham, North Carolina) |
| ABSTRACT | The disclosure provides compounds that inhibit the invasion of host cells by intracellular parasites. These find use, for example, in treating and preventing periodontitis or a periodontitis-related condition or symptom. |
| FILED | Monday, August 16, 2021 |
| APPL NO | 17/402998 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/042 (20130101) A61K 8/42 (20130101) A61K 8/0204 (20130101) A61K 8/4926 (20130101) A61K 31/166 (20130101) A61K 31/439 (20130101) Original (OR) Class A61K 31/4748 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/02 (20180101) A61P 31/04 (20180101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 11/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053465 | Jaenisch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Rudolf Jaenisch (Brookline, Massachusetts); Xin Tang (Quincy, Massachusetts) |
| ABSTRACT | Potassium chloride cotransporter-2 (KCC2) plays a critical role in brain function, and deficiency in KCC2 has been linked to neurological diseases, psychiatric disorders, and central nervous system injuries. In particular, Rett syndrome (RTT), a severe neurodevelopmental disorder caused by mutations in the X-linked gene Methyl CpG binding Protein 2 (MECP2), has been linked to deficits in KCC2. The disclosure reports the use of CRISPR/Cas9 genome-editing technology to generate stem cell-derived, genetically defined KCC2 reporter human neurons for large-scale compound screening. This screening platform has been utilized to identify a number of small molecule compounds that are capable of enhancing KCC2 expression in both wild-type and RTT neurons, as well as organotypical brain slices cultured from wild-type mice. These first-in class compounds may be applied as a novel therapeutic approach to restore the impaired balance between excitation and inhibition observed in neurological diseases, psychiatric disorders, and central nervous system injuries. |
| FILED | Tuesday, April 05, 2022 |
| APPL NO | 17/713880 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/47 (20130101) A61K 31/404 (20130101) A61K 31/496 (20130101) Original (OR) Class A61K 31/519 (20130101) A61K 31/4525 (20130101) A61K 31/4709 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053476 | Lewis et al. |
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| FUNDED BY |
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| APPLICANT(S) | BAYER PHARMA AKTIENGESELLSCHAFT (Berlin, Germany); THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | Bayer Pharma Aktiengesellschaft (Berlin, Germany); The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Timothy A. Lewis (Marlborough, Massachusetts); Alex Burgin (Boston, Massachusetts); Monica Schenone (Chestnut Hill, Massachusetts); Xiaoyun Wu (Winchester, Massachusetts); Heidi Greulich (Arlington, Massachusetts); Matthew Meyerson (Concord, Massachusetts); Luc De Waal (Medford, Massachusetts); Antje Margret Wengner (Berlin, Germany); Knut Eis (Berlin, Germany); Philip Lienau (Berlin, Germany); Ulrike Sack (Berlin, Germany); Martin Lange (Berlin, Germany) |
| ABSTRACT | The present invention features improved compounds, especially methods of identifying patients having cancer using biomarkers (e.g., PDE3A, SLFN12 and/or CREB3L1) that correlate with drug sensitivity and consequently treating a stratified patient population with an agent of the invention (e.g., Compounds 1-6 disclosed herein). |
| FILED | Thursday, January 28, 2021 |
| APPL NO | 17/161612 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/50 (20130101) A61K 31/5377 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 413/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053483 | Ramunas et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | John Ramunas (Menlo Park, California); Eduard Yakubov (Houston, Texas); Helen M. Blau (Menlo Park, California); John Cooke (Houston, Texas) |
| ABSTRACT | Compounds and compositions for the transient expression of exogenous telomerase activity in a cell are provided. The compounds and compositions, which relate to a ribonucleic acid coding for a telomerase reverse transcriptase, are useful in the extension of telomeres in cells needing such treatment. Such cells include, for example, cells that contain shortened telomeres and cells from subjects that may benefit from telomere extension, for example subjects that suffer from, or are at risk of suffering from, age-related or other illnesses. Also provided are methods of extending telomeres through the administration of the provided compounds and compositions to animal cells, either in vitro or in vivo, and kits including the compounds or compositions and instructions for use. |
| FILED | Monday, January 06, 2020 |
| APPL NO | 16/735684 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) Original (OR) Class A61K 38/45 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1276 (20130101) C12N 15/52 (20130101) Enzymes C12Y 207/07049 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053491 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seattle, Washington) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seattle, Washington) |
| INVENTOR(S) | Yvonne Y. Chen (Los Angeles, California); Eugenia Zah (Los Angeles, California); Michael C. Jensen (Seattle, Washington) |
| ABSTRACT | A CD19-OR-CD20 chimeric antigen receptor (CAR) protein construct is provided. Also provided are nucleic acids encoding the CD19-OR-CD20 CAR; and methods of use, e.g. in the treatment of B cell malignancies. The CD19-OR-CD20 CAR of the invention is a bispecific CAR that can trigger T-cell activation upon detection of either CD19 or CD20 (or both). It is a single molecule that confers two-input recognition capability upon human T cells engineered to stably express this CAR. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/238210 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70596 (20130101) C07K 16/46 (20130101) C07K 16/2803 (20130101) C07K 16/2887 (20130101) C07K 2317/31 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053503 | Nabel et al. |
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| FUNDED BY |
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| APPLICANT(S) | SANOFI (Paris, France) |
| ASSIGNEE(S) | SANOFI (Paris, France) |
| INVENTOR(S) | Gary J. Nabel (Bridgewater, New Jersey); Chih-Jen Wei (Bridgewater, New Jersey); Laura Nguyen (Bridgewater, New Jersey); Kurt Swanson (Bridgewater, New Jersey); Te-Hui Chou (Bridgewater, New Jersey) |
| ABSTRACT | This disclosure relates to antigenic EBV polypeptides and their use in eliciting antibodies against EBV. Also disclosed are antigenic polypeptides comprising an EBV polypeptide and a ferritin protein. |
| FILED | Thursday, June 15, 2023 |
| APPL NO | 18/335893 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/162 (20130101) Original (OR) Class A61K 47/00 (20130101) Peptides C07K 14/05 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053511 | Eaves-Pyles et al. |
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| APPLICANT(S) | BOARD OR REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OR REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Tonyia Eaves-Pyles (Galveston, Texas); Richard B. Pyles (Galveston, Texas) |
| ABSTRACT | The present invention includes a composition and method of modulating a dysregulated gut-derived inflammation following a thermal injury comprising: identifying a mammal in need of treatment for the dysregulated gut-derived inflammation following the thermal injury; and providing the mammal with a recombinant Cystatin 9 (CST9) and Cystatin C (CSTC) in a synergistic amount sufficient to restrain or prevent a life-threatening, unrestrained systemic dysregulated gut-derived inflammation in the mammal caused by the thermal injury. |
| FILED | Tuesday, June 16, 2020 |
| APPL NO | 16/903107 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/57 (20130101) Original (OR) Class A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 29/00 (20180101) A61P 31/04 (20180101) A61P 37/02 (20180101) Peptides C07K 14/8139 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053519 | Kwong et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter Kwong (Washington, District of Columbia); Li Ou (Potomac, Maryland); John Mascola (Rockville, Maryland); Baoshan Zhang (Bethesda, Maryland); Kai Xu (Rockville, Maryland); Wing-Pui Kong (Germantown, Maryland); Yaroslav Tsybovsky (Brunswick, Maryland); Cara W. Chao (Bethesda, Maryland); Jeffrey Boyington (Clarksburg, Maryland); Yiran Wang (Bethesda, Maryland) |
| ABSTRACT | Embodiments of immunogenic conjugates including the HIV-1 Env fusion peptide and methods of their use and production are disclosed. In several embodiments, the immunogenic conjugates can be used to generate an immune response to HIV-1 Env in a subject, for example, to treat or prevent an HIV-1 infection in the subject. |
| FILED | Monday, September 23, 2019 |
| APPL NO | 17/277694 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1658 (20130101) A61K 39/21 (20130101) Original (OR) Class A61K 47/64 (20170801) A61K 47/644 (20170801) A61K 47/646 (20170801) A61K 47/6925 (20170801) A61K 2039/645 (20130101) A61K 2039/6031 (20130101) A61K 2039/6037 (20130101) A61K 2039/6068 (20130101) A61K 2039/6075 (20130101) A61K 2039/6081 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053520 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Xuejun Chen (Clarksburg, Maryland); Jeffrey Boyington (Clarksburg, Maryland); Hongying Duan Holdsworth (McLean, Virginia); Cheng Cheng (Bethesda, Maryland); John R. Mascola (Rockville, Maryland) |
| ABSTRACT | Embodiments of immunogens based on the outer domain of HIV-1 gp120 and methods of their use and production are disclosed. Nucleic acid molecules encoding the immunogens are also provided. In several embodiments, the immunogens can be used to prime an immune response to gp120 in a subject, for example, to treat or prevent an HIV-1 infection in the subject. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 17/587817 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) Original (OR) Class A61K 2039/5258 (20130101) A61K 2039/55555 (20130101) Peptides C07K 14/005 (20130101) C07K 14/162 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16023 (20130101) C12N 2740/16043 (20130101) C12N 2740/16111 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) Enzymes C12Y 205/01078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053522 | Kagan |
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| FUNDED BY |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jonathan C. Kagan (Brookline, Massachusetts) |
| ABSTRACT | The present invention provides methods and compositions for specific activation of inflammatory responses in dendritic cells (DCs). 1-palmitoyl-2-arachidonyl-sn-glycero phosphorylcholine (PAPC) and its oxidized variant (oxPAPC) were identified to promote DC-mediated immunity, and are provided as adjuvants in immunostimulatory compositions, including vaccines. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/739953 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Original (OR) Class A61K 2039/57 (20130101) A61K 2039/575 (20130101) A61K 2039/55511 (20130101) A61K 2039/55516 (20130101) A61K 2039/55561 (20130101) A61K 2039/55566 (20130101) A61K 2039/55572 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053527 | Kohane et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel S. Kohane (Newton, Massachusetts); Rong Yang (Cambridge, Massachusetts); Lily Yun Lin (Austin, Texas) |
| ABSTRACT | The present invention provides compositions and methods for delivery of therapeutic agents across an barrier. The compositions include a therapeutic agent (e.g., antimicrobial agent, antibiotic, or anesthetic agent), a permeation enhancer which increases the flux of the therapeutic agent across the barrier, and a matrix forming agent. The matrix forming agent forms a gel at a suitable gelation temperature and rheological properties for use in drug delivery, and in some cases, the gelation temperature and rheological properties are not significantly changed from those of the composition without the permeation enhancer. The invention also provides a matrix forming agent and compositions thereof. Such compositions are particularly useful in the treatment of otitis media. Methods of treatment, methods of delivery, and kits for the compositions described herein are also provided. |
| FILED | Friday, July 23, 2021 |
| APPL NO | 17/383494 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0046 (20130101) A61K 31/407 (20130101) A61K 31/407 (20130101) A61K 31/424 (20130101) A61K 31/424 (20130101) A61K 31/431 (20130101) A61K 31/431 (20130101) A61K 31/445 (20130101) A61K 31/445 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/573 (20130101) A61K 31/573 (20130101) A61K 31/4709 (20130101) A61K 31/4709 (20130101) A61K 31/5383 (20130101) A61K 31/5383 (20130101) A61K 38/12 (20130101) A61K 45/06 (20130101) A61K 47/06 (20130101) A61K 47/10 (20130101) A61K 47/12 (20130101) A61K 47/20 (20130101) A61K 47/22 (20130101) A61K 47/26 (20130101) A61K 47/34 (20130101) Original (OR) Class A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) A61P 31/04 (20180101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/3355 (20130101) C08G 79/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053561 | Desai et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Rajiv Desai (San Diego, California); Neel Satish Joshi (Somerville, Massachusetts); David J. Mooney (Sudbury, Massachusetts); Sandeep T. Koshy (Boston, Massachusetts); Alexander Stafford (Revere, Massachusetts) |
| ABSTRACT | The present disclosure provides click-crosslinked hydrogels and methods of use. |
| FILED | Tuesday, September 15, 2020 |
| APPL NO | 17/022062 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/222 (20130101) A61L 27/3886 (20130101) A61L 2300/22 (20130101) A61L 2300/23 (20130101) A61L 2300/64 (20130101) A61L 2300/252 (20130101) A61L 2300/256 (20130101) A61L 2300/258 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2400/18 (20130101) Heterocyclic Compounds C07D 237/26 (20130101) Peptides C07K 14/78 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 89/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053645 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Wei Liu (Scottsdale, Arizona); Jie Shan (Scottsdale, Arizona) |
| ABSTRACT | Robust optimization systems and methods are provided for intensity modulated proton therapy (IMPT) that may be deployed in a clinically practical way to enable users to control the balance between nominal plan quality and plan robustness in a user-defined way. The method may include a normalized dose interval volume histogram (NDIVH)-based robust optimization, where the normalized dose interval (NDI) is calculated for each voxel considering dose variations in the face of uncertainties. It is then used to create a NDIVH. The area under this NDIVH curve may then be used to quantify plan robustness. By using normalized dose interval volume constraints (NDIVC) to control the shape of the NDIVH curves, plan robustness may be adjusted. The tradeoff between nominal plan quality and plan robustness can be modified in a user-defined way by adjusting positions of the NDIVCs on the NDIVH curves. |
| FILED | Wednesday, August 28, 2019 |
| APPL NO | 17/271751 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1031 (20130101) Original (OR) Class A61N 2005/1087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053774 | Granier et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Robert Granier (Boston, Massachusetts); Ramin Haghgooie (Arlington, Massachusetts); Ken Kotz (Auburndale, Massachusetts); Anne C. Petrofsky (Sudbury, Massachusetts); Ronald G. Tompkins (Boston, Massachusetts) |
| ABSTRACT | A modular analytic system includes a base, at least one fluid sample processing module configured to be removably attached to the base, at least one fluid sample analysis module configured to be removably attached to the base, a fluid actuation module positioned on the base, a fluidic network comprising multiple fluidic channels, in which the fluid actuation module is arranged to control transport of a fluid sample between the at least one sample processing module and the at least one sample analysis module through the fluidic network, and an electronic processor, in which the electronic processor is configured to control operation of the fluid actuation module and receive measurement data from the at least one fluid sample analysis module. |
| FILED | Thursday, February 25, 2021 |
| APPL NO | 17/185177 |
| ART UNIT | 1796 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 3/502738 (20130101) B01L 2200/027 (20130101) B01L 2200/028 (20130101) B01L 2200/0689 (20130101) B01L 2300/0627 (20130101) B01L 2300/0816 (20130101) B01L 2300/0832 (20130101) B01L 2300/0861 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/01 (20240101) G01N 15/12 (20130101) G01N 15/1434 (20130101) G01N 15/1459 (20130101) G01N 21/01 (20130101) G01N 21/78 (20130101) G01N 21/359 (20130101) G01N 21/532 (20130101) G01N 21/6486 (20130101) G01N 35/00029 (20130101) G01N 35/00871 (20130101) G01N 2015/1006 (20130101) G01N 2021/6493 (20130101) G01N 2035/00158 (20130101) G01N 2035/00326 (20130101) G01N 2035/00356 (20130101) G01N 2035/00881 (20130101) G01N 2201/024 (20130101) G01N 2201/062 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053906 | Xiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clemson University Research Foundation (Clemson, South Carolina) |
| ASSIGNEE(S) | Clemson University Research Foundation (Clemson, South Carolina) |
| INVENTOR(S) | Hai Xiao (Clemson, South Carolina); Jianhua Tong (Central, South Carolina); Fei Peng (Clemson, South Carolina); Kyle S. Brinkman (Clemson, South Carolina); Shenglong Mu (Clemson, South Carolina); Jincheng Lei (Clemson, South Carolina); Yuzhe Hong (Clemson, South Carolina); Hua Huang (Clemson, South Carolina); Rajendra Bordia (Seneca, South Carolina) |
| ABSTRACT | A method for fabricating a protonic ceramic energy device includes: coating an electrolyte layer on an anode layer; and densifying the electrolyte layer by a rapid laser reactive sintering (RLRS) process on the electrolyte layer and/or the anode layer to form a half-cell comprising a dense electrolyte and a porous anode. |
| FILED | Wednesday, December 30, 2020 |
| APPL NO | 17/138173 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/402 (20130101) B23K 2103/52 (20180801) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) Manufacture, Shaping, or Supplementary Processes C03B 19/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054447 | Malkas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | Linda H. Malkas (Duarte, California); David Horne (Altadena, California); Robert J. Hickey (Duarte, California); Long Gu (Duarte, California) |
| ABSTRACT | Described herein, inter alia, are compositions of PCNA modulators and methods for treating or preventing cancer. |
| FILED | Wednesday, April 27, 2022 |
| APPL NO | 17/730948 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/4409 (20130101) A61K 31/4418 (20130101) A61K 31/4418 (20130101) A61K 31/4725 (20130101) A61K 31/4725 (20130101) A61K 33/24 (20130101) A61K 33/243 (20190101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Acyclic or Carbocyclic Compounds C07C 233/76 (20130101) Original (OR) Class C07C 237/22 (20130101) Heterocyclic Compounds C07D 213/68 (20130101) C07D 217/26 (20130101) C07D 401/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054466 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Mayland Chang (Granger, Indiana); Shahriar Mobashery (Granger, Indiana); Derong Ding (South Bend, Indiana) |
| ABSTRACT | Clostridium difficile infection (CDI) is a public health threat that results in 14,000 annual deaths in the United States. Challenges involve the production of CDI spores that can remain dormant for years and the production of toxins that damage the gut. Current therapies for CDI include vancomycin and metronidazole, but neither inhibits spore or toxin production. Thus, recurrence of infection occurs in 25% of patients and there are no antibiotics that are effective for multiple recurrences. We describe oxadiazoles with activity against C. difficile, including the highly virulent NAP1/027 strain with increased production of toxins A and B, as well as the additional binary toxin. Oxadiazole 2 is poorly absorbed, thus advantageously achieving high concentrations in the gut. The compound targets peptidoglycan synthesis and inhibits vegetative cells, spores, and toxin production. |
| FILED | Thursday, July 15, 2021 |
| APPL NO | 17/376522 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/12 (20130101) A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/2027 (20130101) A61K 9/2059 (20130101) A61K 9/4866 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 271/06 (20130101) Original (OR) Class C07D 413/04 (20130101) C07D 413/10 (20130101) C07D 413/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054469 | Thatcher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Gregory R Thatcher (Chicago, Illinois); Rui Xiong (Urbana, Illinois); Jiong Zhao (Urbana, Illinois); Debra A. Tonetti (Urbana, Illinois) |
| ABSTRACT | This invention is benzothiophene-based estrogen receptor downregulators and their compositions and uses to treat estrogen-related medical disorders. |
| FILED | Monday, July 26, 2021 |
| APPL NO | 17/385748 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/10 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 333/64 (20130101) Original (OR) Class C07D 409/06 (20130101) C07D 409/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054480 | Makriyannis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MAKScientific, LLC (Burlington, Massachusetts) |
| ASSIGNEE(S) | MAKScientific, LLC (Burlington, Massachusetts) |
| INVENTOR(S) | Alexandros Makriyannis (Watertown, Massachusetts); Kiran Vemuri (Boston, Massachusetts) |
| ABSTRACT | The present invention relates to novel compounds that can act as antidotes for treating “Acute Cannabinoid Overdose” produced by classical cannabinoids such as Δ9-tetrahydrocannabinol (THC) and several synthetic psychoactive cannabinoids (SPCs). The cannabis constituent THC exerts its psychotropic effects via CB1 receptor activation and SPCs mimic the effects of THC with higher potency and severe neurotoxicity. Compounds disclosed in this invention, their enantiomers, diastereomers, geometric isomers, racemates, tautomers, rotamers, atropisomers, metabolites, N-oxides, salts, solvates, hydrates, isotopic variations and their polymorphic forms can be therapeutically useful in an emergency setting for counteracting the intoxicating effects of acute THC ingestion and SPC overdose. Also, aspects of the invention are concerned with pyrazoles, imidazoles, triazoles, thiazoles, oxazoles, dihydropyrazoles, pyrrolidinones, azetidines, oxyazetidines and azaspiro[3.3]heptanes with unique pharmacokinetic and pharmacodynamic properties for treating “Acute Cannabinoid Overdose”. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/392191 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 39/02 (20180101) Heterocyclic Compounds C07D 205/04 (20130101) C07D 207/273 (20130101) C07D 231/14 (20130101) C07D 417/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054491 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin); The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin); The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Alexander E. Arnold (Milwaukee, Wisconsin); Douglas C. Stafford (Stoughton, Wisconsin); James M. Cook (Milwaukee, Wisconsin); Charles W. Emala (Woodcliff Lake, New Jersey); Gloria Forkuo (Milwaukee, Wisconsin); Rajwana Jahan (Milwaukee, Wisconsin); Revathi Kodali (Milwaukee, Wisconsin); Guanguan Li (Milwaukee, Wisconsin); Michael Rajesh Stephen (Milwaukee, Wisconsin) |
| ABSTRACT | The present invention describes substituted benzo[f]imidazo[1,5-a][1,4]diazepines of the formula (I): wherein R1, R2, R2′, R3, and X are as disclosed herein. These compounds target alpha-4 and alpha-5 GABAa receptors and are useful for the treatment of airway hyperresponsiveness and inflammation in asthma. |
| FILED | Thursday, August 11, 2022 |
| APPL NO | 17/886403 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) C07D 487/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054508 | Niu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | The Trustees of Boston College (Chesnut Hill, Massachusetts) |
| INVENTOR(S) | Jia Niu (Lexington, Massachusetts); Chao Liu (Newton, Massachusetts); Cangjie Yang (Brighton, Massachusetts) |
| ABSTRACT | In one aspect, the disclosure relates to a facile strategy to introduce electron-deficient aryl sulfate diesters to silylated hydroxyl groups of carbohydrates and amino acids, among other substrates, wherein selective hydrolysis and the removal of an electron-deficient aromatic group allows for the efficient generation of sulfated carbohydrates, peptides, and other compounds. The incorporation of electron-deficient aryl sulfate diesters in the early stage of the synthesis of glycans, peptides, and the like, disclosed herein avoids time-consuming protecting group manipulations, simplifies the purification of sulfated products, and improves the overall yield and efficiency. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/863347 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 303/26 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 11/00 (20130101) C07H 13/00 (20130101) Original (OR) Class Steroids C07J 41/0072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054519 | Le Nouen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE USA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); CODAGENIX, INC. (Stony Brook, New York) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); Codagenix, Inc. (Stony Brook, New York) |
| INVENTOR(S) | Cyril Le Nouen (Bethesda, Maryland); Ursula J. Buchholz (Silver Spring, Maryland); Peter L. Collins (Silver Spring, Maryland); Steffen Mueller (Farmingdale, New York) |
| ABSTRACT | Reported herein are presumptively de-attenuating mutations that are useful, either individually or in combinations that may include other known mutations, in producing recombinant strains of human respiratory syncytial virus (RSV) exhibiting attenuation phenotypes. Also described herein is a novel RSV construct, Min_L-NPM2-1(N88K)L, which exhibits an attenuated phenotype, is stable and is as immunogenic as wild type RSV. The recombinant RSV strains described here are suitable for use as live-attenuated RSV vaccines. Exemplary vaccine candidates are described. Also provided are polynucleotide sequences capable of encoding the described viruses, as well as methods for producing and using the viruses. |
| FILED | Tuesday, June 28, 2022 |
| APPL NO | 17/851905 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0043 (20130101) A61K 39/155 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) Peptides C07K 14/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/04 (20130101) C12N 2760/00021 (20130101) C12N 2760/00034 (20130101) C12N 2760/00062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054526 | Millay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio); THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio); USA AS REPRESENTED BY THE SECRETARY, DEPT. OF HHS (Bethesda, Maryland) |
| INVENTOR(S) | Douglas Millay (Park Hills, Kentucky); Dilani Gamage (Cincinnati, Ohio); Leonid Chernomordik (North Potomac, Maryland); Evgenia Leikina (Derwood, Maryland) |
| ABSTRACT | Some embodiments of the invention include polypeptides comprising a myomerger polypeptide or an extracellular myomerger polypeptide. Other embodiments of the invention include nucleic acid molecules encoding polypeptides comprising a myomerger polypeptide or an extracellular myomerger polypeptide. Other embodiments of the invention include vectors comprising the nucleic acid molecule. Yet other embodiments of the invention include methods of using a myomerger polypeptide or an extracellular myomerger polypeptide. Additional embodiments of the invention are also discussed herein. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 17/251019 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/17 (20130101) Peptides C07K 14/4716 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054538 | Diskin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California); The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); The Rockefeller University (New York, New York) |
| INVENTOR(S) | Ron Diskin (Rehovot, Israel); Pamela J. Bjorkman (Altadena, California); Michel Nussenzweig (New York, New York); Johannes Scheid (New York, New York) |
| ABSTRACT | Embodiments of the present invention are directed to compositions and methods for anti-HIV (anti-CD4 binding site) potent VRC01-like (PVL) antibodies targeted to gp120 having an amino acid substitution at a residue in the anti-CD4 binding site PVL antibody that is equivalent to Phe43 in CD4, these antibodies having improved potency and breadth. |
| FILED | Thursday, October 13, 2022 |
| APPL NO | 18/046481 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16111 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054541 | Muir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Tom W. Muir (Princeton, New Jersey); Miquel Vila-Perello (Princeton, New Jersey); Zhihua Liu (Plainsborough, New Jersey); Neel H. Shah (Princeton, New Jersey) |
| ABSTRACT | Disclosed herein are split inteins, fused proteins of split inteins, and methods of using split inteins to efficiently purify and modify proteins of interest. |
| FILED | Friday, October 01, 2021 |
| APPL NO | 17/491729 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/195 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2319/50 (20130101) C07K 2319/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) C12P 21/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054607 | Bowman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Christopher N. Bowman (Boulder, Colorado); Nancy Sowan (Boulder, Colorado); Lewis M. Cox (Boulder, Colorado) |
| ABSTRACT | The present invention relates in part to compositions displaying stress relaxation at the polymer-filler interface. The adaptive interface (AI) formed by coupling moieties capable of dynamic covalent chemistry (DCC) within the polymer-filler interface promotes stress relaxation and yields tough, and healable composites. |
| FILED | Tuesday, March 19, 2019 |
| APPL NO | 16/982393 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/887 (20200101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/02 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/3445 (20130101) C08K 7/16 (20130101) Compositions of Macromolecular Compounds C08L 33/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054700 | Schaffer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | David V. Schaffer (Danville, California); Nicole Anne Repina (Albany, California); Ruoxing Lei (Berkeley, California); Thomas Patrick C. McClave (Berkeley, California) |
| ABSTRACT | Provided are systems and methods for spatially and temporally controlling light with an illumination device comprising a light source operably connected to a circuit board, one or more light guide plates, one or more optical masks, a controller, and a computer readable medium, comprising instructions that, when executed by the controller, cause the controller to: illuminate a cell or a substrate with light from the light source, and spatially and temporally control illumination of light to the cell or the substrate with one or more illumination parameters, wherein the one or more light guide plates provides uniform illumination of the light. Also provided herein are methods of screening using the system and/or device of the present disclosure. |
| FILED | Wednesday, May 06, 2020 |
| APPL NO | 17/608896 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 31/08 (20130101) C12M 31/10 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6452 (20130101) G01N 21/6486 (20130101) G01N 2201/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054711 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Si-ping Han (Duarte, California); Marwa Ben Haj Salah (Duarte, California); Lisa Scherer (Duarte, California); William A. Goddard (Pasadena, California); John J. Rossi (Duarte, California) |
| ABSTRACT | Disclosed herein are multi-way oligonucleotide junctions for delivering one or more cargo molecules to a biological target and method of making such junctions. The oligonucleotide junctions are formed by two or more oligonucleotides and are stable outside the cell and easily dissociate inside the cell to release the cargo molecule(s). One or more cargo molecules as well as delivery ligand can be loaded to the junctions for targeted delivery. Also disclosed are nanostructures including one or more junctions attached to each other for delivering two or more cargo molecules. |
| FILED | Saturday, July 14, 2018 |
| APPL NO | 16/631134 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 2310/52 (20130101) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
12054734 — Purification and purity assessment of RNA molecules synthesized with modified nucleosides
| US 12054734 | Weissman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Drew Weissman (Wynnewood, Pennsylvania); Katalin Kariko (Rydal, Pennsylvania) |
| ABSTRACT | This invention provides purified preparations of an RNA, oligoribonucleotide, or polyribonucleotide comprising a modified nucleoside, and methods of assessing purity of purified preparations of an RNA, oligoribonucleotide, or polyribonucleotide comprising a modified nucleoside. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/338795 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Peptides C07K 14/52 (20130101) C07K 14/475 (20130101) C07K 14/505 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) Original (OR) Class C12N 2310/335 (20130101) C12N 2320/30 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054736 | Wussow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Felix Wussow (Glendora, California); Don J. Diamond (Glendora, California); Heidi Contreras (Pasadena, California) |
| ABSTRACT | A vaccine composition comprising an immunologically effective amount of recombinant modified vaccinia Ankara (rMVA) virus comprising IE1, IE2 and pp65 or antigenic fragments thereof, which is genetically stable after at least 10 passages. A method of improving the stability of such rMVA upon passage by including one or more of the modifications: (1) inserting one or more nucleic acid sequences encoding the CMV antigens or antigenic fragments thereof into one or more insertion sites including but not limited to 044L/045L, IGR3, G1L/18R, and Del3 but not including Del2; (2) codon optimizing the nucleic acid sequences encoding the CMV antigens by removing consecutive cytosines or guanines; and (3) introducing one or more mutations in the amino acid sequences of the CMV antigens. |
| FILED | Wednesday, November 11, 2020 |
| APPL NO | 17/095300 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/245 (20130101) A61K 2039/70 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2710/16122 (20130101) C12N 2710/16134 (20130101) C12N 2710/24134 (20130101) C12N 2710/24143 (20130101) C12N 2800/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054742 | Rao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Rajesh Rao (Ann Arbor, Michigan); Qiang Li (Ann Arbor, Michigan) |
| ABSTRACT | The disclosure relates to methods for producing mesodermal lineage cells, cardiac lineage cells, hematopoietic lineage cells, retinal lineage cells, and combinations thereof. In some aspects, the disclosure relates to methods of producing mixed tissue organoids comprising retinal lineage cells and cardiac lineage cells. When interaction of WDR5 protein at the binding pocket/interaction surface with RBBP5/MYC/KANSL2 is disrupted in the embryonic stem cell for a set period of time after differentiation of the embryonic stem cell has begun, and the disruption of that interaction is subsequently removed, differentiation of the embryonic stem cell to a mesodermal lineage cell is obtained. Such mesodermal lineage cells may, in some methods of the disclosure, be subsequently differentiated into cardiac lineage cells and hematopoietic lineage cells. The disclosure also relates to method for producing mixed lineage organoids, comprising retinal and mesodermal, including cardiac, lineage cells in a single organoid. The disclosure also relates to cells and organoids obtained by the methods, uses of the cells and organoids, and kits comprising the cells and/or reagents for producing them. |
| FILED | Friday, January 18, 2019 |
| APPL NO | 16/251740 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0037 (20130101) C12N 5/062 (20130101) C12N 5/0606 (20130101) Original (OR) Class C12N 5/0621 (20130101) C12N 5/0657 (20130101) C12N 15/85 (20130101) C12N 2500/99 (20130101) C12N 2501/22 (20130101) C12N 2501/385 (20130101) C12N 2501/998 (20130101) C12N 2501/2303 (20130101) C12N 2506/02 (20130101) C12N 2510/00 (20130101) C12N 2513/00 (20130101) C12N 2533/90 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054744 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jeffrey Miller (Minneapolis, Minnesota); Frank Cichocki (Minneapolis, Minnesota); Yenan Bryceson (Stockholm, Sweden); Heinrich Schlums (Stockholm, Sweden) |
| ABSTRACT | This disclosure describes an adaptive NK cell, an isolated population of adaptive Natural Killer (NK) cells, a composition including an adaptive NK cell, and methods for producing, preparing, and using an adaptive NK cell or an isolated population or composition including an adaptive NK cell. The adaptive NK cells may be used to treat a viral infection or a tumor. |
| FILED | Wednesday, April 07, 2021 |
| APPL NO | 17/224966 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/245 (20130101) A61K 45/06 (20130101) A61K 2039/572 (20130101) A61K 2039/585 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0646 (20130101) Original (OR) Class C12N 7/00 (20130101) C12N 2501/04 (20130101) C12N 2501/42 (20130101) C12N 2501/599 (20130101) C12N 2501/2315 (20130101) C12N 2501/2321 (20130101) C12N 2502/1121 (20130101) C12N 2502/1157 (20130101) C12N 2502/1352 (20130101) C12N 2710/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054749 | Collins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The Research Foundation for the State University of New York (Albany, New York) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH and HUMAN SERVICES (Bethesda, Maryland); The Research Foundation for the State University of New York (Albany, New York) |
| INVENTOR(S) | Peter L. Collins (Silver Spring, Maryland); Cyril Le Nouen (Bethesda, Maryland); Linda G. Brock (Bethesda, Maryland); Ursula J. Buchholz (Silver Spring, Maryland); Joshua Marc Dinapoli (Lexington, Massachusetts); Steffen Mueller (Kings Point, New York); Eckard Wimmer (E. Setauket, New York) |
| ABSTRACT | Described herein are RSV polynucleotide sequences that make use of multiple codons that are containing silent nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce a numerous synonymous codons into the genome. Due to the large number of defects involved, the attenuated viruses disclosed herein provide a means of producing attenuated, live vaccines against RSV. |
| FILED | Thursday, June 02, 2022 |
| APPL NO | 17/831259 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/155 (20130101) A61K 2039/53 (20130101) A61K 2039/55 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2760/00021 (20130101) C12N 2760/00034 (20130101) C12N 2760/00062 (20130101) C12N 2760/18522 (20130101) C12N 2760/18534 (20130101) C12N 2760/18561 (20130101) C12N 2760/18562 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054768 | Robinson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Peter Robinson (Berkeley, California); Cheng-Ting Tsai (Berkeley, California); Carolyn Bertozzi (Stanford, California) |
| ABSTRACT | Methods are provided for detecting antigen binding agents in samples. Aspects of the methods include detection of the aggregation of antigen binding agents with polynucleotide-bound antigens by sensitive proximity-based association of the antigen-bound polynucleotides. Aspects of the methods also include methods for the detection of such proximity-based association through nucleic acid amplification. In addition, compositions, e.g., reagents, kits, and devices, useful in practicing various embodiments of the methods are provided. |
| FILED | Tuesday, September 14, 2021 |
| APPL NO | 17/474424 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6804 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 2525/117 (20130101) C12Q 2525/155 (20130101) C12Q 2525/197 (20130101) C12Q 2531/113 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054775 | Akeson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Mark A. Akeson (Santa Cruz, California); David W. Deamer (Santa Cruz, California); William B. Dunbar (Santa Cruz, California); Kate Lieberman (Santa Cruz, California); Noah A. Wilson (Felton, California) |
| ABSTRACT | Devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore are provided. The devices and methods also determine (˜>50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by the interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof. |
| FILED | Tuesday, June 09, 2020 |
| APPL NO | 16/897052 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/54 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) Original (OR) Class C12Q 2521/101 (20130101) C12Q 2522/101 (20130101) C12Q 2523/307 (20130101) C12Q 2525/301 (20130101) C12Q 2527/127 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) C12Q 2565/631 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/29 (20210101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3278 (20130101) G01N 27/4166 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054777 | Fan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANDFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Hei-Mun Christina Fan (Fremont, California); Stephen R. Quake (Stanford, California) |
| ABSTRACT | Disclosed is a method to achieve digital quantification of DNA (i.e., counting differences between identical sequences) using direct shotgun sequencing followed by mapping to the chromosome of origin and enumeration of fragments per chromosome. The preferred method uses massively parallel sequencing, which can produce tens of millions of short sequence tags in a single run and enabling a sampling that can be statistically evaluated. By counting the number of sequence tags mapped to a predefined window in each chromosome, the over- or under-representation of any chromosome in maternal plasma DNA contributed by an aneuploid fetus can be detected. This method does not require the differentiation of fetal versus maternal DNA. The median count of autosomal values is used as a normalization constant to account for differences in total number of sequence tags is used for comparison between samples and between chromosomes. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/852663 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48 (20130101) G01N 2800/387 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054781 | Bettegowda et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Chetan Bettegowda (Perry Hall, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland); Yuxuan Wang (Baltimore, Maryland); Luis Diaz (Ellicot City, Maryland); Nickolas Papadopoulos (Towson, Maryland) |
| ABSTRACT | As cell-free DNA from brain and spinal cord tumors cannot usually be detected in the blood, we assessed the cerebrospinal fluid (CSF) that bathes the CNS for tumor DNA, here termed CSF-tDNA. The results suggest that CSF-tDNA could be useful for the management of patients with primary tumors of the brain or spinal cord. |
| FILED | Tuesday, July 12, 2016 |
| APPL NO | 15/744299 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054785 | Kennedy et al. |
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| FUNDED BY |
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| APPLICANT(S) | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Richard B. Kennedy (Rochester, Minnesota); Gregory A. Poland (Marco Island, Florida); Inna G. Ovsyannikova (Rochester, Minnesota); Iana H. Haralambieva (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials involved in using measles viruses. For example, methods and materials for identifying mammals (e.g., humans) likely to respond to standard measles virus vaccines or standard measles virus-based therapies as well as methods and materials for identifying mammals (e.g., humans) unlikely to respond to standard measles virus vaccines or standard measles virus-based therapies are provided. |
| FILED | Tuesday, December 21, 2021 |
| APPL NO | 17/557125 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 39/165 (20130101) A61K 2039/572 (20130101) A61K 2039/575 (20130101) A61K 2039/55588 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) A61P 31/14 (20180101) A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/18434 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054787 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Xiaole Liu (Wayland, Massachusetts); Peng Jiang (Boston, Massachusetts) |
| ABSTRACT | The present invention relates to gene expression signatures that predict response and resistance to targeted therapy and immunotherapy. |
| FILED | Wednesday, October 19, 2022 |
| APPL NO | 18/047910 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055535 | Hazen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | Stanley L. Hazen (Pepper Pike, Ohio); Zeneng Wang (Cleveland, Ohio); Bruce S. Levison (Twinsburg, Ohio) |
| ABSTRACT | Methods of characterizing a test subject's risk of having or developing cardiovascular disease are provided. The methods include using an analytic device to determine levels of choline-related trimethylamine-containing compounds such as trimethylamine N-oxide, choline, or betaine in a biological sample obtained from the subject and comparing the levels of the choline-related trimethylamine-containing compound in the subject's biological sample to a control value. The test subject's risk of having cardiovascular disease is then characterized as higher if the levels of the choline-related trimethylamine-containing compound are higher than the control value. Also provided are methods of identifying a subject at risk of experiencing a complication of atherosclerotic cardiovascular disease, and methods of evaluating the efficacy of a cardiovascular therapeutic agent in a subject with cardiovascular disease using levels of choline-related trimethylamine-containing compounds. |
| FILED | Tuesday, February 04, 2020 |
| APPL NO | 16/781409 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/49 (20130101) Original (OR) Class G01N 33/92 (20130101) G01N 33/493 (20130101) G01N 33/6893 (20130101) G01N 2800/32 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) G01N 2800/323 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0036 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/174614 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055536 | Cheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Ji-Xin Cheng (Newton, Massachusetts); Junjie Li (Arlington, Massachusetts); Yuying Tan (Allston, Massachusetts); Daniela Matei (Chicago, Illinois); Guangyuan Zhao (Chicago, Illinois) |
| ABSTRACT | Disclosed is an assay for determining resistance in a target cell or tissue to a therapy associated with cellular stress using chemical microscopy and high-throughput single cell analysis to determine functional metabolic alteration, including determining metabolic reprogramming in a target cell or tissue to a therapy associated with cellular stress, and methods of using the assays. |
| FILED | Monday, May 15, 2023 |
| APPL NO | 18/317637 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 27/30 (20130101) G01N 27/416 (20130101) G01N 33/492 (20130101) Original (OR) Class G01N 33/48735 (20130101) G01N 2800/52 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/60 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/10 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055547 | Condeelis et al. |
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| FUNDED BY |
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| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York) |
| INVENTOR(S) | John S. Condeelis (Bronx, New York); Allison S. Harney (Bronx, New York) |
| ABSTRACT | Disclosed are kits and methods for detecting the presence of tumor sites that are active in tumor cell dissemination and uses thereof for determining the risk of tumor cells undergoing hematogenous metastasis, for assessing the prognosis of a subject undergoing treatment for a localized tumor, for determining a course of treatment for a localized tumor, and for identifying agents to treat or prevent hematogenous metastasis. |
| FILED | Tuesday, March 23, 2021 |
| APPL NO | 17/209670 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/22 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/57415 (20130101) G01N 33/57484 (20130101) Original (OR) Class G01N 2800/50 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055553 | Zivkovic et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Angela Zivkovic (Saint Helena, California); Carlito B. Lebrilla (Davis, California); Emanual Maverakis (Folsom, California) |
| ABSTRACT | Methods of detecting altered HDL functionality as well as adjusting HDL functionality are described. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 16/491541 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7004 (20130101) A61K 31/7008 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) Original (OR) Class G01N 2333/81 (20130101) G01N 2333/775 (20130101) G01N 2400/00 (20130101) G01N 2800/7095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12056796 | Tao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Shengzhen Tao (Rochester, Minnesota); Shuai Leng (Rochester, Minnesota); Cynthia H. McCollough (Byron, Minnesota) |
| ABSTRACT | A system and method is provided for high fidelity multi-energy CT processing. This system and method exploits prior knowledge, where prior knowledge may include redundant information existing in the CT images, such as spatial redundancy between a thick slice and a thin slice encompassed by or close to the thick slice, or the spatiospectral redundancy between the image output of multi-energy CT processing and the source multi-energy CT images. The system and method retains structural details, spatial resolution, spectral fidelity, and noise texture while achieving noise reduction. The method reduces image noise and increases the contrast-to-noise ratio in processed images, while simultaneously maintaining image details and natural appearance of the image to enhance detectability and facilitate reader acceptance. |
| FILED | Friday, June 28, 2019 |
| APPL NO | 17/256404 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) A61B 6/5211 (20130101) A61B 6/5258 (20130101) Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 5/70 (20240101) G06T 11/005 (20130101) G06T 11/008 (20130101) Original (OR) Class G06T 2207/10081 (20130101) G06T 2211/408 (20130101) G06T 2211/424 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12056877 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Yufan He (Baltimore, Maryland); Jerry L. Prince (Baltimore, Maryland); Aaron Carass (Towson, Maryland) |
| ABSTRACT | A device receives a two-dimensional (2-D) image that depicts a cross-sectional view of a macula comprised of layers and boundaries to segment the layers, and determines spatial coordinates of the 2-D image that include x-coordinates and y-coordinates. The device uses a data model, that has been trained using a deep learning technique, to process the 2-D image and the spatial coordinates to generate boundary maps that indicate likelihoods of voxels of the 2-D image being in positions that are part of particular boundaries. The device determines, by analyzing the boundary maps, an initial set of boundary positions, and determines a final set of boundary positions by using a topological order identification technique to refine the initial set of boundary positions. The device determines the thickness levels of the layers of the macula based on the final set of boundary positions, and performs one or more actions based on the thickness levels. |
| FILED | Wednesday, March 25, 2020 |
| APPL NO | 17/594191 |
| ART UNIT | 2672 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) A61B 3/0025 (20130101) A61B 3/0058 (20130101) A61B 3/1005 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) Original (OR) Class G06T 7/0012 (20130101) G06T 7/12 (20170101) G06T 7/73 (20170101) G06T 7/143 (20170101) G06T 2207/10101 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30041 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/10 (20180101) G16H 70/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12056878 | Fuchs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Thomas Fuchs (New York, New York); David Joon Ho (New York, New York) |
| ABSTRACT | Described herein are systems and methods of training models to segment images. A device may identify a training dataset. The training dataset may include images each having a region of interest. The training dataset may include first annotations. The device may train, using the training dataset, an image segmentation model having parameters to generate a corresponding first segmented images. The device may provide the first segmented images for presentation on a user interface to obtain feedback. The device may receive, via the user interface, a feedback dataset including second annotations for at least a subset of the first segmented images. Each of the second annotations may label at least a second portion of the region of interest in a corresponding image of the subset. The device may retrain, using the feedback dataset received via the user interface, the image segmentation model. |
| FILED | Monday, May 15, 2023 |
| APPL NO | 18/197463 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/24 (20230101) Image Data Processing or Generation, in General G06T 7/11 (20170101) Original (OR) Class G06T 7/187 (20170101) G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) G06T 2207/30096 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/26 (20220101) G06V 10/82 (20220101) G06V 10/751 (20220101) G06V 10/764 (20220101) G06V 20/70 (20220101) G06V 20/695 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057232 | Clifford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Georgia Tech Research Foundation (Atlanta, Georgia) |
| INVENTOR(S) | Gari Clifford (Decatur, Georgia); Ayse Cakmak (Atlanta, Georgia); Amit Shah (Atlanta, Georgia); Erik Reinertsen (Atlanta, Georgia) |
| ABSTRACT | Methods and systems for monitoring of sensor data for processing by machine-learning models to generate event predictions to estimate a risk a medical event are provided. An electronic device or wearable smart device may monitor the output of various sensors to collect data related to a person's activity level, location changes, and communications and may use this information as input to a personalized trained machine-learning model to predict a likelihood of an event. |
| FILED | Thursday, December 05, 2019 |
| APPL NO | 17/295248 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/2431 (20230101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 40/67 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) Original (OR) Class G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057233 | Patek et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | Stephen D. Patek (Charlottesville, Virginia); Marc D. Breton (Charlottesville, Virginia) |
| ABSTRACT | A method and system use mathematical models and available patient information to virtualize a continuous glucose monitoring trace for a period of time. Such a method and system can generate the virtualized trace when episodic patient data is incomplete. Such a method and system can also rely on self-monitored blood glucose measurement information to improve the virtualized continuous glucose monitoring trace. |
| FILED | Wednesday, March 16, 2022 |
| APPL NO | 17/696466 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 40/63 (20180101) G16H 50/50 (20180101) Original (OR) Class G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12053288 | {hacek over (S)}arlija et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NeuroGeneces Inc. (Santa Fe, New Mexico) |
| ASSIGNEE(S) | NeuroGeneces Inc. (Santa Fe, New Mexico) |
| INVENTOR(S) | Marko {hacek over (S)}arlija (Zagreb, Croatia); Michael Kenneth Comerford, III (Santa Fe, New Mexico); Karen Crow (Santa Fe, New Mexico) |
| ABSTRACT | Some systems, devices and methods detailed herein provide a system for use in determining metrics of a subject. The system can provide, as an output, a function-metric value determined based on a defined relationship between physiological measures and a chronological age. |
| FILED | Thursday, April 20, 2023 |
| APPL NO | 18/137250 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/31 (20210101) A61B 5/72 (20130101) A61B 5/0205 (20130101) A61B 5/291 (20210101) A61B 5/369 (20210101) A61B 5/374 (20210101) A61B 5/377 (20210101) Original (OR) Class A61B 5/384 (20210101) A61B 5/725 (20130101) A61B 5/02416 (20130101) A61B 5/4806 (20130101) A61B 5/4809 (20130101) A61B 5/4812 (20130101) A61B 5/4815 (20130101) A61B 5/7235 (20130101) A61B 5/7267 (20130101) A61B 5/7275 (20130101) Electric Digital Data Processing G06F 3/015 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) G06N 3/06 (20130101) G06N 3/08 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053446 | Teitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| ASSIGNEE(S) | Ting Therapeutics LLC (Omaha, Nebraska); St Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Tal Teitz (Omaha, Nebraska); Jian Zuo (Omaha, Nebraska); Taosheng Chen (Germantown, Tennessee) |
| ABSTRACT | Oseltamivir is used as active agent to treat a hearing impairment and to prevent a hearing impairment, and a method of treating and/or preventing hearing impairments or disorders using Oseltamivir are disclosed. Oseltamivir exhibits excellent protection against noise-induced hearing loss and against cisplatin-induced hearing loss. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/129267 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/196 (20130101) Original (OR) Class A61K 31/282 (20130101) A61K 31/7028 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053561 | Desai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Rajiv Desai (San Diego, California); Neel Satish Joshi (Somerville, Massachusetts); David J. Mooney (Sudbury, Massachusetts); Sandeep T. Koshy (Boston, Massachusetts); Alexander Stafford (Revere, Massachusetts) |
| ABSTRACT | The present disclosure provides click-crosslinked hydrogels and methods of use. |
| FILED | Tuesday, September 15, 2020 |
| APPL NO | 17/022062 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/52 (20130101) Original (OR) Class A61L 27/54 (20130101) A61L 27/222 (20130101) A61L 27/3886 (20130101) A61L 2300/22 (20130101) A61L 2300/23 (20130101) A61L 2300/64 (20130101) A61L 2300/252 (20130101) A61L 2300/256 (20130101) A61L 2300/258 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2400/18 (20130101) Heterocyclic Compounds C07D 237/26 (20130101) Peptides C07K 14/78 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 89/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053628 | McLaughlin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micro-Leads, Inc. (Somerville, Massachusetts) |
| ASSIGNEE(S) | Micro-Leads, Inc. (Somerville, Massachusetts) |
| INVENTOR(S) | Bryan L. McLaughlin (Cambridge, Massachusetts); Girish Chitnis (Watertown, Massachusetts); John Ogren (Antrim, New Hampshire) |
| ABSTRACT | An electrode array system includes a unitary body forming a plurality of apertures, and a plurality of continuous conductive elements at least partially encapsulated within the unitary body. The continuous conductive elements include/form a plurality of contacts, a plurality of electrode sites configured to couple with neural tissue (e.g., a spinal nerve or peripheral nerve), and a plurality of interconnects extending between the plurality of contacts and the plurality of electrode sites. The plurality of electrode sites are aligned with the plurality of apertures, and the plurality of apertures expose the plurality of electrodes. |
| FILED | Monday, September 13, 2021 |
| APPL NO | 17/473387 |
| ART UNIT | 3796 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) A61N 1/0553 (20130101) Original (OR) Class A61N 1/0556 (20130101) A61N 1/0558 (20130101) A61N 1/36062 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054245 | Parsons et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Thomas Dewey Parsons (Fort Worth, Texas); Charles Eric Covington (Colleyville, Texas); Kent E. Donaldson (Fort Worth, Texas); Andrew Thomas Carter (Richland Hills, Texas) |
| ABSTRACT | In an embodiment, an aircraft includes a drive system, a main engine coupled to the drive system to provide first power, and a supplemental engine coupled to the drive system to provide second power additive to the first power. The aircraft also includes a control system to control the main engine and the supplemental engine to optimize usage of the supplemental engine. The control system is operable to maintain the supplemental engine in a reduced power state at least until a determination is made that supplemental power is needed to satisfy a total power demand of the drive system. The control system is also operable to determine that supplemental power is needed to satisfy the total power demand of the drive system. The control system is further operable to increase a power level of the supplemental engine in response to the determination that supplemental power is needed. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/867231 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/12 (20130101) Original (OR) Class Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 31/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054276 | Maxwell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | John Nathan Maxwell (Keller, Texas) |
| ABSTRACT | A method of assembling an aircraft gearbox. The method includes mounting an outer race and a plurality of rollers of a roller bearing in an opening of a gearbox housing, mating a cylindrical guide sleeve having a lead-in chamfer with a gear assembly having a gear and a cylindrical shaft such that a trailing shoulder of the guide sleeve is positioned proximate a leading shoulder of the shaft, the shaft including an inner race of the roller bearing, axially passing the lead-in chamfer of the guide sleeve through the plurality of rollers, radially outwardly urging the rollers toward the outer race with the guide sleeve, axially passing the leading shoulder of the shaft through the plurality of rollers, positioning the inner race relative to the plurality of rollers to form the roller bearing and removing the guide sleeve from the gear assembly. |
| FILED | Tuesday, May 17, 2022 |
| APPL NO | 17/746786 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 15/003 (20130101) B23P 2700/01 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 35/00 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/90 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49696 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054391 | Tour et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | James Mitchell Tour (Bellaire, Texas); Duy X. Luong (Houston, Texas); Wilbur Carter Kittrell (Houston, Texas); Weiyin Chen (Houston, Texas) |
| ABSTRACT | Methods for the synthesis of graphene, and more particularly the method of synthesizing graphene by flash Joule heating (FJH). Such methods can be used to synthesize turbostratic graphene (including low-defect turbostratic graphene) in bulk quantities. Such methods can further be used to synthesize composite materials and 2D materials. |
| FILED | Friday, August 23, 2019 |
| APPL NO | 17/272895 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) Original (OR) Class C01B 2204/22 (20130101) C01B 2204/32 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2002/85 (20130101) C01P 2002/88 (20130101) C01P 2004/04 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054406 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | The Trustees of the Stevens Institute of Technology (Hoboken, New Jersey) |
| INVENTOR(S) | Eui-Hyeok Yang (Fort Lee, New Jersey); Jian Xu (West Lafayette, Indiana); Wei Xu (Farmingdale, New York); Brendan Englot (New York, New York); Chang-Hwan Choi (Tenafly, New Jersey) |
| ABSTRACT | Smart membranes (14) are integrated into a small, unmanned surface vessel (20) to enable the efficient, automated cleanup of oil spills. Such a vessel (20) has the potential to provide a low-cost, modular solution for day-to-day oil-spill cleanup operations, especially in confined aquatic areas, such as under piers and in the small spaces between marine vessels and piers. The smart membranes (14) are provided on the surface of a conveyor belt (34) that circulates the membranes (14) through the surrounding body of water (10) for oil collection, as well as through an internal reduction chamber (22) of the vessel (20) for oil release. The smart membranes (14) are adapted to attract and repel oil (12) in response to low-voltage commands applied across the conveyor belt (34), using a process that is repeatable for a number of cycles, offering high efficiency and long durability (FIG. 5). |
| FILED | Thursday, August 04, 2022 |
| APPL NO | 17/881406 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/40 (20130101) Original (OR) Class C02F 1/285 (20130101) C02F 2101/32 (20130101) C02F 2103/007 (20130101) C02F 2301/08 (20130101) C02F 2303/16 (20130101) C02F 2305/04 (20130101) C02F 2305/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054407 | Waller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gordon H. Waller (Vienna, Virginia); Danielle M. Paynter (Vienna, Virginia) |
| ABSTRACT | Apparatus, methods, and systems are provided for treating oil-in-water emulsions by in situ production of magnetic FeOx nanoparticles. |
| FILED | Friday, May 08, 2020 |
| APPL NO | 16/869728 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 2259/80 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/463 (20130101) Original (OR) Class C02F 1/488 (20130101) C02F 2101/32 (20130101) C02F 2201/4614 (20130101) C02F 2201/46135 (20130101) C02F 2209/02 (20130101) C02F 2303/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054428 | Jawaid et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Rome, New York) |
| INVENTOR(S) | Ali M. Jawaid (Fairborn, Ohio); Richard A. Vaia (Beavercreek, Ohio); Asra Hassan (Tallahassee, Florida) |
| ABSTRACT | A method of making a layered MXene material comprises a) introducing dried MAX phase powder into a vessel under anhydrous, inert conditions, the MAX phase powder comprising a general formula of Mn+1AXn (n=1, 2, 3, or 4), wherein M is a transition metal or p-block metalloid selected from the group consisting of Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, W, Re, Cu, Ni, Ag, Zn, Cd, In, Sn, and Pb; interlayer A is a Group III, IV, or V metalloid selected from the group consisting of Al, Si, Ga, Ge, In, Sn, Pb, As, Bi, Sb, and X is one of C (carbon) and N (nitrogen); b) introducing a halogen and solvent to the dried MAX phase to create a halogen solution having a predetermined concentration; c) allowing a reaction to proceed for about 24 hours between 30-90° C. to create a reaction slurry comprising a MXene material. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/037883 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/0602 (20130101) C01B 32/90 (20170801) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/20 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/622 (20130101) C04B 35/5611 (20130101) Original (OR) Class C04B 41/009 (20130101) C04B 41/5338 (20130101) C04B 2235/74 (20130101) C04B 2235/444 (20130101) C04B 2235/3817 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054447 | Malkas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | City of Hope (Duarte, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California) |
| INVENTOR(S) | Linda H. Malkas (Duarte, California); David Horne (Altadena, California); Robert J. Hickey (Duarte, California); Long Gu (Duarte, California) |
| ABSTRACT | Described herein, inter alia, are compositions of PCNA modulators and methods for treating or preventing cancer. |
| FILED | Wednesday, April 27, 2022 |
| APPL NO | 17/730948 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/4409 (20130101) A61K 31/4418 (20130101) A61K 31/4418 (20130101) A61K 31/4725 (20130101) A61K 31/4725 (20130101) A61K 33/24 (20130101) A61K 33/243 (20190101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) Acyclic or Carbocyclic Compounds C07C 233/76 (20130101) Original (OR) Class C07C 237/22 (20130101) Heterocyclic Compounds C07D 213/68 (20130101) C07D 217/26 (20130101) C07D 401/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054459 | Blumberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southwest Research Institute (San Antonio, Texas) |
| ASSIGNEE(S) | SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas) |
| INVENTOR(S) | Shawn T. Blumberg (San Antonio, Texas); Antonio Menchaca (Seguin, Texas); Christopher Dorsey (San Antonio, Texas); Asa Waterman (San Antonio, Texas) |
| ABSTRACT | Purification of bis-quaternary pyridinium oximes (BQPO) which may serve as organophosphorus nerve agent antidotes. |
| FILED | Tuesday, February 01, 2022 |
| APPL NO | 17/649581 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 213/81 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054808 | Matzdorf et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Patuxent River, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Craig Matzdorf (Hollywood, Maryland); Michael Brindza (Leonardtown, Maryland) |
| ABSTRACT | A powdered alloy with a chemical composition of AlxSi, where X is an amount of Si from 10 to 30 weight percent. More specifically, a powdered alloy with a chemical composition of AlxSiySnzIn, where X is an amount of Si from 10 to 30 weight percent, Y is an amount of Sn from 0.01 to 0.50 weight percent, and Z is an amount of In from 0.005 to 0.05 weight percent. |
| FILED | Monday, July 10, 2023 |
| APPL NO | 18/219902 |
| ART UNIT | 1759 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 9/04 (20130101) B22F 2301/052 (20130101) Alloys C22C 1/026 (20130101) Original (OR) Class C22C 1/0416 (20130101) C22C 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054809 | Giri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of Army (Washington, District of Columbia) |
| INVENTOR(S) | Anit K. Giri (Abingdon, Maryland); Anthony J. Roberts (Chesapeake City, Maryland); Billy C. Hornbuckle (Aberdeen, Maryland); Scott M. Grendahl (Newark, Delaware); Kristopher A. Darling (Havre de Grace, Maryland) |
| ABSTRACT | Alloys comprised of a refined microstructure, ultrafine or nano scaled, that when reacted with water or any liquid containing water will spontaneously and rapidly produce hydrogen at ambient or elevated temperature are described. These metals, termed here as aluminum based nanogalvanic alloys will have applications that include but are not limited to energy generation on demand. The alloys may be composed of primarily aluminum and other metals e.g. tin bismuth, indium, gallium, lead, etc. and/or carbon, and mixtures and alloys thereof. The alloys may be processed by ball milling for the purpose of synthesizing powder feed stocks, in which each powder particle will have the above mentioned characteristics. These powders can be used in their inherent form or consolidated using commercially available techniques for the purpose of manufacturing useful functional components. |
| FILED | Monday, September 23, 2019 |
| APPL NO | 16/579089 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/07 (20220101) B22F 1/07 (20220101) B22F 1/07 (20220101) B22F 1/054 (20220101) B22F 3/02 (20130101) B22F 9/04 (20130101) B22F 2009/043 (20130101) B22F 2009/043 (20130101) B22F 2207/13 (20130101) B22F 2207/13 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/08 (20130101) Alloys C22C 1/0416 (20130101) Original (OR) Class C22C 1/0416 (20130101) C22C 1/0416 (20130101) C22C 1/0416 (20130101) C22C 1/0483 (20130101) C22C 1/0483 (20130101) C22C 1/0483 (20130101) C22C 21/003 (20130101) C22C 21/08 (20130101) C22C 2200/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054812 | Ramakrishnan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MRL MATERIALS RESOURCES LLC (Beavercreek, Ohio) |
| ASSIGNEE(S) | MRL Materials Resources LLC (Beavercreek, Ohio) |
| INVENTOR(S) | Abhishek Ramakrishnan (Beavercreek, Ohio); Daniel P. Satko (Centerville, Ohio); Ayman A. Salem (Dayton, Ohio) |
| ABSTRACT | Magnesium alloys and a process of manufacturing an article using magnesium alloys. During additive manufacturing, where the magnesium alloy is being deposited in a layer-by-layer manner, solidification of the melted portion of a deposited layer is performed in such a way as to ensure that about 15 percent or more of the portion being solidified includes a non-equilibrium eutectic constituent. This in turn reduces the likelihood of encountering solidification conditions that otherwise would lead to hot tearing problems. Further, upon subsequent heat treatment of the solidified layer, the eutectic constituents that were used for hot tearing resistance are dissolved so that the solidified layer may be returned to a substantially single-phase magnesium matrix such that desirable material properties such as improved flammability point, improved corrosion resistance and one or more of high yield strength, ultimate tensile strength and elongation are promoted. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738648 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/25 (20210101) B22F 10/28 (20210101) B22F 10/64 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/00 (20141201) B33Y 40/20 (20200101) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Alloys C22C 1/04 (20130101) C22C 1/0408 (20130101) C22C 23/06 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/25 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054817 | Lambert et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | United States of America, represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul Lambert (Columbia, Maryland); Matthew Draper (Annandale, Virginia); Matthew Sinfield (Glenwood, Maryland); Daniel Bechetti (Columbia, Maryland) |
| ABSTRACT | The invention is a high strength austenitic steel composition having increased strength and toughness characteristics, applicable for use in a seawater environment. The high strength austenitic steel may include nanometer-scale carbides, carbonitrides of vanadium, and carbides and carbonitrides having molybdenum, titanium, and niobium. The austenitic steel includes, 0.15-0.5 wt. % of carbon, 0-0.8 wt. % of silicon 6-14 wt. % of manganese, 9-13.5 wt. % of nickel, 0-3 wt. % of copper; 0.8-2.2 wt. % of vanadium, 0-4 wt. % of molybdenum, 0-4 wt. % of chromium; 0-0.9 wt. % of aluminum, 0-0.1 wt. % of calcium, 0-0.3 wt. % of titanium, 0-0.6 wt. % of niobium, 0-0.2 wt. % of tungsten, 0-0.2 wt. % of nitrogen, 0-0.1 wt. % of cerium, 0-0.1 wt. % of lanthanum, 0-0.05 wt. % of sulfur, and 0-0.05 wt. % of phosphorus. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 17/523863 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 2211/001 (20130101) Alloys C22C 38/001 (20130101) C22C 38/002 (20130101) C22C 38/02 (20130101) C22C 38/005 (20130101) C22C 38/06 (20130101) C22C 38/38 (20130101) C22C 38/42 (20130101) C22C 38/44 (20130101) C22C 38/46 (20130101) C22C 38/48 (20130101) C22C 38/50 (20130101) C22C 38/52 (20130101) C22C 38/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054831 | Arumugam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oceanit Laboratories, Inc. (Honolulu, Hawaii) |
| ASSIGNEE(S) | Oceanit Laboratories, Inc. (Honolulu, Hawaii) |
| INVENTOR(S) | Ganesh Kumar Arumugam (Honolulu, Hawaii); Ashavani Kumar (Honolulu, Hawaii); Vinod P. Veedu (Houston, Texas) |
| ABSTRACT | A surface modification method involves oxidizing a surface of a material and etching the surface, and repeating the oxidizing and etching one or more times until desired nanostructures are created in the surface. The desired nanostructures make the nanostructured surface superhydrophilic. Hydrophilic properties of the surface may be further developed by application of hydrophilic material, and by application of functionalized micro/nanoparticles to the hydrophilic material. Substitution of hydrophobic material for the hydrophilic material creates a superhydrophobic surface. Further addition of an omniphobic coating to the functionalized micro/nanoparticles creates a durable omniphobic surface. |
| FILED | Friday, July 19, 2019 |
| APPL NO | 16/517166 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 28/04 (20130101) Original (OR) Class Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 11/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054980 | Chapla et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Kevin M. Chapla (Melissa, Texas); Catherine Trent (Allen, Texas) |
| ABSTRACT | Disclosed herein is a panel assembly configured to form a mullion joint. The panel assembly can comprise a panel composed of a material substrate that, in some examples, can be transparent to radio frequency signals. The panel assembly can further comprise a first bezel configured to frame a perimeter of the panel on a first side of the panel. The panel assembly can comprise a second bezel configured to frame the perimeter of the panel on a second side of the panel opposite of the first side, the second bezel comprising cogs formed on a first edge of the second bezel. The cogs of the second bezel can be configured to receive and join with cogs of a bezel of a second panel assembly to form a mullion joint. The mullion joint can be transparent, opaque, or partially transparent to radio frequency signals and/or visible light. |
| FILED | Friday, March 18, 2022 |
| APPL NO | 17/698981 |
| ART UNIT | 3635 — Static Structures, Supports and Furniture |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/1492 (20130101) Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 1/363 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055476 | Jalali et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Bahram Jalali (Los Angeles, California); Eric D. Diebold (Los Angeles, California); Brandon Buckley (Los Angeles, California) |
| ABSTRACT | An imaging flow cytometry apparatus and method which allows registering multiple locations across a cell, and/or across multiple flow channels, in parallel using radio-frequency-tagged emission (FIRE) coupled with a parallel optical detection scheme toward increasing analysis throughput. An optical source is modulated by multiple RF frequencies to produce an optical interrogation beam having a spatially distributed beat frequency. This beam is directed to one or more focused streams of cells whose responsive fluorescence, in different frequencies, is registered in parallel by an optical detector. |
| FILED | Monday, June 26, 2023 |
| APPL NO | 18/214300 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 15/1459 (20130101) G01N 15/1484 (20130101) G01N 21/64 (20130101) G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 33/537 (20130101) G01N 2015/1006 (20130101) G01N 2015/1477 (20130101) G01N 2021/6421 (20130101) G01N 2201/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055547 | Condeelis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York) |
| INVENTOR(S) | John S. Condeelis (Bronx, New York); Allison S. Harney (Bronx, New York) |
| ABSTRACT | Disclosed are kits and methods for detecting the presence of tumor sites that are active in tumor cell dissemination and uses thereof for determining the risk of tumor cells undergoing hematogenous metastasis, for assessing the prognosis of a subject undergoing treatment for a localized tumor, for determining a course of treatment for a localized tumor, and for identifying agents to treat or prevent hematogenous metastasis. |
| FILED | Tuesday, March 23, 2021 |
| APPL NO | 17/209670 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/22 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/57415 (20130101) G01N 33/57484 (20130101) Original (OR) Class G01N 2800/50 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055576 | Tews et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Schweitzer Engineering Laboratories, Inc. (Pullman, Washington) |
| ASSIGNEE(S) | Schweitzer Engineering Laboratories, Inc. (Pullman, Washington) |
| INVENTOR(S) | Cody W. Tews (Portland, Oregon); Nicholas C. Seeley (Pullman, Washington) |
| ABSTRACT | The present disclosure relates to systems and methods for calculating noise distributions in an electric power system. In one embodiment, a system to calculate a noise distribution in an electric power system may comprise a measurement subsystem to obtain a plurality of raw measurements of a parameter in the electric power system. A noise distribution determination subsystem may be configured to generate a plurality of scaled raw measurements from the plurality of raw measurements, generate a power spectrum density from the plurality of scaled raw measurements, generate a cumulative distribution from the power spectrum density, and determine a noise distribution from the power spectrum density. A protective action subsystem may monitor the parameter in the electric power system to identify a signal of interest by utilizing, at least in part, the noise distribution and generating a control action in response to the signal. |
| FILED | Thursday, September 01, 2022 |
| APPL NO | 17/929101 |
| ART UNIT | 2839 — Organic Chemistry |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/086 (20130101) Original (OR) Class Emergency Protective Circuit Arrangements H02H 1/0007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055617 | Nelatury |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Charles Nelatury (Ridley Park, Pennsylvania) |
| ABSTRACT | An integrator for use with a current sensor provides a feedback loop using a frequency discriminator, reducing drift while maintaining wide bandwidth. |
| FILED | Tuesday, September 27, 2022 |
| APPL NO | 17/935687 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 35/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055798 | Moss et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Analog Photonics LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | Analog Photonics LLC (Boston, Massachusetts) |
| INVENTOR(S) | Benjamin Roy Moss (Cambridge, Massachusetts); Erman Timurdogan (Somerville, Massachusetts); Christopher Vincent Poulton (Cambridge, Massachusetts); Shahriar Shahramian (Warren, New Jersey) |
| ABSTRACT | Controlling an optical phased array includes applying optical phase shifts by an array of phase shifter (PS) elements, each PS element applying an optical phase shift based on an input voltage signal applied across first and second terminals of the PS element, providing output voltage signals from an array of driver elements. During a charging time period, each driver element provides an output voltage signal to determine a corresponding input voltage signal applied across at least one of the PS elements; an array of switches control connectivity between the driver elements and respective PS elements; and all of the second terminals of all of the PS elements in the array of PS elements are maintained at a common voltage. The total number of switches in the array of switches is at least as large as the total number of PS elements in the array of PS elements. |
| FILED | Thursday, March 04, 2021 |
| APPL NO | 17/192169 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/48 (20130101) G01S 7/481 (20130101) G01S 7/4815 (20130101) Optical Elements, Systems, or Apparatus G02B 26/06 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0121 (20130101) Original (OR) Class G02F 2203/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055820 | Basu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Rajratan Basu (Columbia, Maryland) |
| ABSTRACT | An electro-optical liquid crystal cell comprising a first substrate, a first layer of chromium (Cr), a first layer of vertically aligned carbon nanotubes (VA-CNT) capped with nickel nanoparticles, and a layer of liquid crystal. Furthermore, the electro-optical liquid crystal cell can comprise a second layer of VA-CNT capped with nickel nanoparticles, a second layer of Cr, and a second substrate. This electro-optic VA-CNT-based liquid crystal cell exhibits the required electro-optic effect needed for a liquid crystal display. |
| FILED | Monday, November 15, 2021 |
| APPL NO | 17/526395 |
| ART UNIT | 2871 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0018 (20130101) G02F 1/061 (20130101) G02F 1/133715 (20210101) G02F 1/133719 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055836 | McManamon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Exciting Technology, LLC (Dayton, Ohio) |
| ASSIGNEE(S) | Exciting Technology LLC (Dayton, Ohio) |
| INVENTOR(S) | Paul F. McManamon (Dayton, Ohio); Abtin Ataei (Oakwood, Ohio) |
| ABSTRACT | An example system includes a high-side electrode layer including a number of discrete electrodes and a low-side electrode layer. The system further includes an electro-optic (EO) layer including an EO active material positioned between the high-side electrode layer and the low-side electrode layer, thereby forming a number of active cells of the EO layer. Each of the number of active cells of the EO layer includes a portion of the EO layer that is positioned between one of the discrete electrodes and the low-side electrode layer. The example system further includes an insulator operationally coupled to the active cells of the EO layer, and at least partially positioned between a first one of the active cells and a second one of the active cells. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/245532 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/139 (20130101) G02F 1/292 (20130101) G02F 1/311 (20210101) G02F 1/3133 (20130101) Original (OR) Class G02F 1/3138 (20130101) G02F 2203/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12056062 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARM LIMITED (Cambridge, United Kingdom) |
| ASSIGNEE(S) | Arm Limited (Cambridge, United Kingdom) |
| INVENTOR(S) | Bradley John Smith (Suffolk, United Kingdom); Thomas Christopher Grocutt (Cambridgshire, United Kingdom); François Christopher Jacques Botman (Cambridgshire, United Kingdom) |
| ABSTRACT | Apparatus comprises a processor to execute program instructions stored at respective memory addresses, processing of the program instructions being constrained by a prevailing capability defining at least access permissions to a set of one or more memory addresses; the processor comprising: control flow change handling circuitry to perform a control flow change operation, the control flow change operation defining a control flow change target address indicating the address of a program instruction for execution after the control flow change operation; and capability generating circuitry to determine, in dependence on the control flow change target address, an address at which capability access permissions data is stored; the capability generating circuitry being configured to retrieve the capability access permissions data and to generate a capability for use as a next prevailing capability in dependence upon at least the capability access permissions data. |
| FILED | Wednesday, December 02, 2020 |
| APPL NO | 17/759973 |
| ART UNIT | 2135 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 9/35 (20130101) G06F 9/3005 (20130101) G06F 12/1458 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12056456 | Luu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Rome, New York) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Rome, New York) |
| INVENTOR(S) | Jonathan W. Luu (Xenia, Ohio); Kevin P. Fenton (Colorado Springs, Colorado); Steve Simske (Fort Collins, Colorado) |
| ABSTRACT | An apparatus for automated safety data sheet (SDS) processing that translates the entire SDSs from numerous chemical vendors, and in various formats (.pdf, .doc, .txt, .jpg, gif, .png, etc) to machine-encoded text by employing optical, RFID, and infrared scanning, reading and writing devices. The apparatus reads and assess documents as a human would; ensuring that the documents are compliant, ensuring reported values are within expected thresholds, and that there are no conflicts in hazardous material classification, and comparing to similar products for more environmentally friendly alternatives. The apparatus further employs a processor that computes meta-algorithms as trainable neural networks that allow the invention to “learn” and appropriately classify values and calculate statistical probabilities for output accuracy and precision. |
| FILED | Monday, June 06, 2022 |
| APPL NO | 17/832800 |
| ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 40/51 (20200101) Original (OR) Class G06F 40/205 (20200101) Image or Video Recognition or Understanding G06V 30/224 (20220101) G06V 30/1916 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12056967 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); The United States of America As Represented By the Secretary of The Army (Washington, District of Columbia) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, None); The United States of America As Represented By the Secretary of The Army (Washington, District of Columbia) |
| INVENTOR(S) | Zongxuan Sun (Plymouth, Minnesota); Xiaonan Dong (Hermosa Beach, California); Clifford Francis Webster Goertemiller (Saint Paul, Minnesota); Kenneth Seong-uk Kim (Clarksville, Maryland); Chol-bum Mike Kweon (Hanover, Maryland) |
| ABSTRACT | In some examples, a method for estimating the cetane number of a fuel includes receiving current engine operating condition measurements from a compression ignition (CI) engine using the fuel, and determining a value for a current engine performance indicator. The method further includes determining a projected engine performance indicator value for the CI engine based on the current estimated cetane number, current engine control signals and the current engine operating condition measurements. The method also includes determining that a difference between the value of the current engine performance indicator and the projected engine performance indicator value is greater than a threshold amount. If the difference is greater than the threshold amount, the method also includes determining a new estimated cetane number. |
| FILED | Friday, May 12, 2023 |
| APPL NO | 18/316764 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/0808 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057555 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); U.S. ARMY RESEARCH LABORATORY (Adelphi, Maryland) |
| ASSIGNEE(S) | University of Maryland (, None); U.S. Army Research Laboratory (, None) |
| INVENTOR(S) | Chunsheng Wang (Silver Spring, Maryland); Kang Xu (Potomac, Maryland); Liumin Suo (Greenbelt, Maryland) |
| ABSTRACT | The present invention is directed to a hybrid high voltage aqueous electrolyte battery that combines Ni/Mg2NiH4 and Mg-ion rechargeable battery chemistries. The hybrid aqueous electrolyte battery can be used for plug-in hybrid electrical vehicles and electric vehicles. |
| FILED | Wednesday, January 28, 2015 |
| APPL NO | 15/114997 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/48 (20130101) H01M 4/466 (20130101) H01M 4/485 (20130101) H01M 10/36 (20130101) Original (OR) Class H01M 2200/20 (20130101) H01M 2220/20 (20130101) H01M 2300/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057556 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Kang Xu (Potomac, Maryland); Arthur Von Wald Cresce (Beltsville, Maryland); Oleg A. Borodin (Laurel, Maryland); Chunsheng Wang (Silver Spring, Maryland); Liumin Suo (Greenbelt, Maryland) |
| ABSTRACT | The present invention is directed to aqueous and hybrid aqueous electrolytes that comprise a lithium salt. The present invention is also directed to methods of making the electrolytes and methods of using the electrolytes in batteries and other electrochemical technologies. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346673 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/5815 (20130101) H01M 4/5825 (20130101) H01M 10/26 (20130101) H01M 10/36 (20130101) Original (OR) Class H01M 10/056 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0002 (20130101) H01M 2300/0014 (20130101) H01M 2300/0025 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057645 | Garren |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Alington, Virginia) |
| INVENTOR(S) | David Alan Garren (Clifton, Virgin Islands) |
| ABSTRACT | The invention relates to a communication device radiating a purely dipole structure. The communication device includes a metallic sphere having a central axis and electrical wiring wound azimuthally around the central axis of the metallic sphere so that an electric current density of the electric wiring is proportional to a sine of a spherical elevation angle of the metallic sphere. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/865884 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 7/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057646 | Zekios et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Constantinos L. Zekios (Miami, Florida); Stavros Georgakopoulos (Miami, Florida); Nicholas E. Russo (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Constantinos L. Zekios (Miami, Florida); Stavros Georgakopoulos (Miami, Florida); Nicholas E. Russo (Miami, Florida) |
| ABSTRACT | Multi-band, microstrip patch antennas, as well as methods of fabricating the same and methods of using the same, are provided. A decoupling technique can be used where strategically etched slots are provided between the tightly coupled microstrip patch antennas, and the appropriate mode excitation of the corresponding patch antennas can be used. The antennas have high isolation between the frequency bands of operation. Multi-band operation can be achieved by exciting a different mode on each contiguous portion of the patch antenna. |
| FILED | Wednesday, July 06, 2022 |
| APPL NO | 17/810889 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 5/378 (20150115) H01Q 9/0421 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057757 | McAleenan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KAZAK TECHNOLOGIES, INC. (Woolwich, Maine) |
| ASSIGNEE(S) | Michael McAleenan (Woolwich, Maine) |
| INVENTOR(S) | Michael McAleenan (Woolwich, Maine) |
| ABSTRACT | A flywheel includes a hub configured to rotate about a longitudinal axis. At least one member having a laminate casing connected to the hub, the laminate casing is formed with an enclosed space for housing at least one mass with a fixed shape. The enclosed space is structured to control radial displacement of the at least one mass. Wherein upon rotation, an operational radial force applies a through thickness laminate radial load to the laminate casing, while simultaneously radially displacing the at least one mass to apply a controllable compressive load on the laminate casing. The applied controllable compressive load increases a predetermined laminate loading capacity by an amount of compressive load counteracting the through thickness laminate radial load, resulting in a corresponding increase in a flywheel angular velocity, that therefore increases an amount of energy stored by the at least one energy storage unit. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/158468 |
| ART UNIT | 3656 — Material and Article Handling |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 10/26 (20130101) Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology B60Y 2400/162 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 3/08 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 2361/55 (20130101) Springs; Shock-absorbers; Means for Damping Vibration F16F 15/31 (20130101) F16F 15/305 (20130101) F16F 2230/0058 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 15/007 (20200101) Dynamo-electric Machines H02K 7/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12058262 | Ramanujan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARCHITECTURE TECHNOLOGY CORPORATION (Eden Prairie, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ranga S. Ramanujan (Medina, Minnesota); Deborah K. Charan (Minneapolis, Minnesota); Barry A. Trent (Chanhassen, Minnesota); Jordan C. Bonney (Bloomington, Minnesota) |
| ABSTRACT | Embodiments for a computer readable medium including a software module are provided. The software module causes one or more processing devices to obtain a biometric identifier from a user. Access to a resource is requested by providing a software credential token and the biometric identifier. The software credential token corresponds to a hardware credential token, and the hardware credential token is one of a set of hardware credential tokens that are used to access the resource. An indication that access to the resource has been granted is received and after receiving the indication an indication that the access to the resource has been revoked is received. After receiving the indication that access to the resource has been revoked, a biometric identifier is re-obtained from a user and access to the resource is re-requested by providing a software credential token and the re-obtained biometric identifier. |
| FILED | Thursday, December 22, 2022 |
| APPL NO | 18/145841 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3213 (20130101) Original (OR) Class H04L 9/3228 (20130101) H04L 9/3234 (20130101) H04L 9/3263 (20130101) H04L 63/083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12058265 | Khoury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON BBN TECHNOLOGIES CORP. (Cambridge, Massachusetts) |
| INVENTOR(S) | Joud Khoury (Boston, Massachusetts); Michael Hassan Atighetchi (Framingham, Massachusetts); Zachary Ratliff (Somerville, Massachusetts); Katarzyna Lucja Olejnik (Arlington, Massachusetts) |
| ABSTRACT | Techniques for verifiable computation for cross-domain information sharing are disclosed. An untrusted node in a distributed cross-domain solution (CDS) system is configured to: receive a first data item and a first cryptographic proof associated with the first data item; perform a computation on the first data item including one or more of filtering, sanitizing, or validating the first data item, to obtain a second data item; generate, using a proof-carrying data (PCD) computation, a second cryptographic proof that indicates (a) validity of the first cryptographic proof and (b) integrity of the first computation on the first data item; and transmits the second data item and the second cryptographic proof to a recipient node in the distributed CDS system. Alternatively or additionally, the untrusted node may be configured to transmit a cryptographic proof to a trusted aggregator in the CDS system. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/138399 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3218 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US D1038006 | Di Benedetto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Giuseppe Di Benedetto (Nutley, New Jersey); Lauren Morris (Midland Park, New Jersey); Daniel Schmidt (Ambler, Pennsylvania); Peggy Sanchez (Sparta, New Jersey); Aaron Stern (Piscataway, New Jersey); Donald Skelton (Bridgewater, New Jersey) |
| ABSTRACT | |
| FILED | Thursday, September 22, 2022 |
| APPL NO | 29/866666 |
| ART UNIT | 2914 — Design |
| CURRENT CPC | Equipment for production, distribution, or transformation of energy D13/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12052953 | Alcantar |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Norma Arcelia Alcantar (Tampa, Florida) |
| ABSTRACT | A bio-enriched soil and method of production is presented. If water supply is scant, bio-enriched soil technologies (BEST) are able to attract, store, and transport water and nutrient molecules to a plant in a controlled way. If the water or nutrient resources are excessive, BEST can release the excess and supply only what is needed. Hence, bio-enriched soil can function in climates in which crops normally are under stress by increasing the bioavailability of nutrients and water. |
| FILED | Monday, April 05, 2021 |
| APPL NO | 17/222653 |
| ART UNIT | 3674 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 24/00 (20180201) Original (OR) Class A01G 24/22 (20180201) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 17/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053288 | {hacek over (S)}arlija et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NeuroGeneces Inc. (Santa Fe, New Mexico) |
| ASSIGNEE(S) | NeuroGeneces Inc. (Santa Fe, New Mexico) |
| INVENTOR(S) | Marko {hacek over (S)}arlija (Zagreb, Croatia); Michael Kenneth Comerford, III (Santa Fe, New Mexico); Karen Crow (Santa Fe, New Mexico) |
| ABSTRACT | Some systems, devices and methods detailed herein provide a system for use in determining metrics of a subject. The system can provide, as an output, a function-metric value determined based on a defined relationship between physiological measures and a chronological age. |
| FILED | Thursday, April 20, 2023 |
| APPL NO | 18/137250 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/31 (20210101) A61B 5/72 (20130101) A61B 5/0205 (20130101) A61B 5/291 (20210101) A61B 5/369 (20210101) A61B 5/374 (20210101) A61B 5/377 (20210101) Original (OR) Class A61B 5/384 (20210101) A61B 5/725 (20130101) A61B 5/02416 (20130101) A61B 5/4806 (20130101) A61B 5/4809 (20130101) A61B 5/4812 (20130101) A61B 5/4815 (20130101) A61B 5/7235 (20130101) A61B 5/7267 (20130101) A61B 5/7275 (20130101) Electric Digital Data Processing G06F 3/015 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) G06N 3/06 (20130101) G06N 3/08 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053765 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of New Hampshire (Durham, New Hampshire) |
| ASSIGNEE(S) | University of New Hampshire (Durham, New Hampshire); The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Gonghu Li (Newmarket, New Hampshire); Anatoly Frenkel (Great Neck, New York); Peipei Huang (Dover, New Hampshire); Jiahao Huang (Port Jefferson, New York) |
| ABSTRACT | A composition of a photocatalyst, a method of manufacturing the photocatalyst, and a method of chemically reducing carbon dioxide to carbon monoxide using the photocatalyst under visible-light irradiation is provided. The photocatalyst comprises a transition metal ion and graphitic carbon nitride and includes single metal sites on carbon nitride. Under visible light, the metal sites that are coordinated to nitrogen atoms get activated, without the use of additional ligands, to catalyze the reduction of carbon dioxide to selectively produce carbon monoxide. The photocatalytic reduction of carbon dioxide to carbon monoxide is highly efficient, resulting a turnover number of more than 800 for carbon monoxide production in 2 hours. The composition is useful in converting carbon dioxide into useful chemicals and carbon-based fuels. A functional model of molecular catalysts for efficient carbon dioxide reduction is also present. |
| FILED | Wednesday, June 03, 2020 |
| APPL NO | 16/891442 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/1815 (20130101) Original (OR) Class B01J 35/39 (20240101) B01J 37/04 (20130101) B01J 2231/005 (20130101) B01J 2231/625 (20130101) B01J 2531/845 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/40 (20170801) Heterocyclic Compounds C07D 487/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053769 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honda Motor Co., Ltd. (Tokyo, Japan); The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | Honda Motor Co., Ltd. (Tokyo, Japan); The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Xufan Li (Fremont, California); Avetik Harutyunyan (Santa Clara, California); Xiangye Liu (Xi'an, China PRC); Baiching Li (New York, New York); James Curtis Hone (New York, New York); Daniel V. Esposito (New York, New York) |
| ABSTRACT | Aspects of the present disclosure generally relate to catalyst compositions including metal chalcogenides, processes for producing such catalyst compositions, processes for enhancing catalytic active sites in such catalyst compositions, and uses of such catalyst compositions in, e.g., processes for producing conversion products. In an aspect, a process for forming a catalyst composition is provided. The process includes introducing an electrolyte material and an amphiphile material to a metal chalcogenide to form the catalyst composition. In another aspect, a catalyst composition is provided. The catalyst composition includes a metal chalcogenide, an electrolyte material, and an amphiphile material. Devices for hydrogen evolution reaction are also provided. |
| FILED | Wednesday, December 21, 2022 |
| APPL NO | 18/086089 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 27/043 (20130101) B01J 27/051 (20130101) B01J 27/0573 (20130101) B01J 27/0576 (20130101) B01J 37/344 (20130101) Original (OR) Class Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/075 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053810 | Trumble et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Kevin Paul Trumble (West Lafayette, Indiana); Xiaolong Bai (West Lafayette, Indiana); Srinivasan Chandrasekar (West Lafayette, Indiana); James Mann (Avon, Indiana) |
| ABSTRACT | Processes for producing sheet metal products by machining a solid metal body with a cutting tool in a single step to continuously produce a continuous bulk form from material obtained from the solid metal body, and without performing a hot rolling operation thereon, cold rolling the continuous bulk form to produce a sheet metal product. The machining step is a large-strain machining process capable of being directly performed on an as-cast ingot or other solid body to produce a continuous intermediate product that can be directly cold rolled without any intervening hot rolling operation, and optionally without homogenization or annealing. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/681480 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Rolling of Metal B21B 1/26 (20130101) Original (OR) Class Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 8/0236 (20130101) C21D 9/46 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053984 | Foresti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniele Foresti (Somerville, Massachusetts); Jennifer A. Lewis (Cambridge, Massachusetts); Armand Kurum (Cambridge, Massachusetts) |
| ABSTRACT | A method of acoustophoretic printing comprises generating an acoustic field at a first end of an acoustic chamber fully or partially enclosed by sound-reflecting walls. The acoustic field interacts with the sound-reflecting walls and travels through the acoustic chamber. The acoustic field is enhanced in a chamber outlet at a second end of the acoustic chamber. An ink is delivered into a nozzle positioned within the acoustic chamber. The nozzle has a nozzle opening projecting into the chamber outlet. The ink travels through the nozzle and is exposed to the enhanced acoustic field at the nozzle opening, and a predetermined volume of the ink is ejected from the nozzle opening and out of the acoustic chamber. |
| FILED | Wednesday, January 06, 2021 |
| APPL NO | 17/142575 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 1/54 (20130101) Shaping or Working of Foodstuffs, Not Fully Covered by a Single Other Subclass A23P 20/20 (20160801) A23P 2020/253 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/24 (20130101) A61L 27/54 (20130101) A61L 27/3834 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) B29C 64/209 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201) Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/14008 (20130101) Original (OR) Class Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 5/0023 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054406 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE STEVENS INSTITUTE OF TECHNOLOGY (Hoboken, New Jersey) |
| ASSIGNEE(S) | The Trustees of the Stevens Institute of Technology (Hoboken, New Jersey) |
| INVENTOR(S) | Eui-Hyeok Yang (Fort Lee, New Jersey); Jian Xu (West Lafayette, Indiana); Wei Xu (Farmingdale, New York); Brendan Englot (New York, New York); Chang-Hwan Choi (Tenafly, New Jersey) |
| ABSTRACT | Smart membranes (14) are integrated into a small, unmanned surface vessel (20) to enable the efficient, automated cleanup of oil spills. Such a vessel (20) has the potential to provide a low-cost, modular solution for day-to-day oil-spill cleanup operations, especially in confined aquatic areas, such as under piers and in the small spaces between marine vessels and piers. The smart membranes (14) are provided on the surface of a conveyor belt (34) that circulates the membranes (14) through the surrounding body of water (10) for oil collection, as well as through an internal reduction chamber (22) of the vessel (20) for oil release. The smart membranes (14) are adapted to attract and repel oil (12) in response to low-voltage commands applied across the conveyor belt (34), using a process that is repeatable for a number of cycles, offering high efficiency and long durability (FIG. 5). |
| FILED | Thursday, August 04, 2022 |
| APPL NO | 17/881406 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/40 (20130101) Original (OR) Class C02F 1/285 (20130101) C02F 2101/32 (20130101) C02F 2103/007 (20130101) C02F 2301/08 (20130101) C02F 2303/16 (20130101) C02F 2305/04 (20130101) C02F 2305/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054436 | Duan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Xiangfeng Duan (Los Angeles, California); Yu Huang (Los Angeles, California); Xiang Xu (Los Angeles, California) |
| ABSTRACT | A ceramic aerogel includes a porous framework including interconnected double-paned wall structures of a ceramic material, wherein each double-paned wall structure includes a pair of walls spaced apart by a gap. |
| FILED | Thursday, January 23, 2020 |
| APPL NO | 17/427277 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/14 (20130101) C04B 35/80 (20130101) C04B 35/583 (20130101) C04B 35/62884 (20130101) C04B 38/00 (20130101) C04B 38/0067 (20130101) C04B 38/0074 (20130101) C04B 38/0615 (20130101) Original (OR) Class C04B 2235/386 (20130101) C04B 2235/614 (20130101) C04B 2235/767 (20130101) C04B 2235/963 (20130101) C04B 2235/3418 (20130101) C04B 2235/3834 (20130101) C04B 2235/9607 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/76 (20130101) E04B 2001/742 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054570 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jeremiah A. Johnson (Boston, Massachusetts); Wenxu Zhang (Belmont, Massachusetts); Peyton Shieh (Cambridge, Massachusetts); Keith Husted (Boston, Massachusetts) |
| ABSTRACT | The present disclosure describes functional oligomers or functional polymers. The functional oligomers or functional polymers may contain functional groups, e.g., —OH and/or —CHO. The functional oligomers or functional polymers may be obtained from hydrolyzing certain copolymers and may be soluble in commercially available solvents. The copolymers may be thermosetting polymers. The functional oligomers and functional polymers may be useful for recycling thermosetting polymers and may be useful as starting materials for preparing additional oligomers or polymers. |
| FILED | Tuesday, September 15, 2020 |
| APPL NO | 17/022021 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Heterocyclic Compounds C07D 321/12 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/12 (20130101) C08F 232/08 (20130101) Original (OR) Class C08F 234/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054607 | Bowman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Christopher N. Bowman (Boulder, Colorado); Nancy Sowan (Boulder, Colorado); Lewis M. Cox (Boulder, Colorado) |
| ABSTRACT | The present invention relates in part to compositions displaying stress relaxation at the polymer-filler interface. The adaptive interface (AI) formed by coupling moieties capable of dynamic covalent chemistry (DCC) within the polymer-filler interface promotes stress relaxation and yields tough, and healable composites. |
| FILED | Tuesday, March 19, 2019 |
| APPL NO | 16/982393 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 6/887 (20200101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/02 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/3445 (20130101) C08K 7/16 (20130101) Compositions of Macromolecular Compounds C08L 33/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054653 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Xuanhe Zhao (Allston, Massachusetts); Hyunwoo Yuk (Cambridge, Massachusetts); Xiaoyu Chen (Cambridge, Massachusetts) |
| ABSTRACT | An adhesive material that provides fast and robust adhesion on wet surfaces, where the adhesion formed is detachable on-demand. The adhesive material is formed of one or more hydrophilic polymers or copolymers grafted with one or more amine coupling groups via a plurality of cleavable physical bonds and/or cleavable covalent bonds and one or more cross linkers. Application of the adhesive material on a wet surface causes the adhesive material to absorb liquid to thereby swell the adhesive material to form a layer of hydrogel, resulting in the formation of temporary crosslinks followed by covalent crosslinks with the surface. Introducing a triggering agent cleaves the cleavable physical bonds and/or cleavable covalent bonds to allow for non-traumatic detachment of the adhesive material from the surface. |
| FILED | Monday, May 24, 2021 |
| APPL NO | 17/327944 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 24/0031 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0025 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/20 (20180101) C09J 7/32 (20180101) Original (OR) Class C09J 105/00 (20130101) C09J 109/04 (20130101) C09J 125/08 (20130101) C09J 129/04 (20130101) C09J 133/10 (20130101) C09J 133/26 (20130101) C09J 133/064 (20130101) C09J 133/066 (20130101) C09J 151/003 (20130101) C09J 175/00 (20130101) C09J 181/08 (20130101) C09J 2301/10 (20200801) C09J 2301/306 (20200801) C09J 2301/502 (20200801) C09J 2405/00 (20130101) C09J 2429/00 (20130101) C09J 2433/00 (20130101) C09J 2451/00 (20130101) C09J 2475/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054711 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Si-ping Han (Duarte, California); Marwa Ben Haj Salah (Duarte, California); Lisa Scherer (Duarte, California); William A. Goddard (Pasadena, California); John J. Rossi (Duarte, California) |
| ABSTRACT | Disclosed herein are multi-way oligonucleotide junctions for delivering one or more cargo molecules to a biological target and method of making such junctions. The oligonucleotide junctions are formed by two or more oligonucleotides and are stable outside the cell and easily dissociate inside the cell to release the cargo molecule(s). One or more cargo molecules as well as delivery ligand can be loaded to the junctions for targeted delivery. Also disclosed are nanostructures including one or more junctions attached to each other for delivering two or more cargo molecules. |
| FILED | Saturday, July 14, 2018 |
| APPL NO | 16/631134 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 2310/52 (20130101) C12N 2320/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054789 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Jared L. Anderson (Ames, Iowa); Byron F. Brehm-Stecher (Ames, Iowa); Kevin D. Clark (Ames, Iowa); Stephanie A. Hice (Ames, Iowa) |
| ABSTRACT | In this disclosure, a method or kit for using the method of extracting, concentrating, and detecting microbes from a sample is disclosed. The method disclosed herein use transition or rare earth metal-based magnetic ionic liquids (MILs) to extract viable microbes from a sample and to detect them via an amplification-based method and/or a non-amplification-based methods. The method and kit can be used in-field and on-site for detection of viable microbes in a sample within about an hour, without using any powered heat source or powered tool. |
| FILED | Monday, February 17, 2020 |
| APPL NO | 16/792734 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/003 (20130101) C07F 13/005 (20130101) C07F 15/045 (20130101) C07F 15/065 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/02 (20130101) C12N 1/20 (20130101) C12N 15/1013 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) C12Q 1/24 (20130101) C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6806 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054837 | Pham et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ELECTRASTEEL, INC. (Boulder, Colorado) |
| ASSIGNEE(S) | ELECTRASTEEL, INC. (Boulder, Colorado) |
| INVENTOR(S) | Ai Quoc Pham (Boulder, Colorado); Sandeep Nijhawan (Boulder, Colorado); Adolfredo Alvarez (Boulder, Colorado); Steven Fatur (Boulder, Colorado) |
| ABSTRACT | Methods and systems for dissolving an iron-containing ore are disclosed. For example, a method of processing and dissolving an iron-containing ore comprises: thermally reducing one or more non-magnetite iron oxide materials in the iron-containing ore to form magnetite in the presence of a reductant, thereby forming thermally-reduced ore; and dissolving at least a portion of the thermally-reduced ore using an acid to form an acidic iron-salt solution; wherein the acidic iron-salt solution comprises protons electrochemically generated in an electrochemical cell. |
| FILED | Wednesday, July 26, 2023 |
| APPL NO | 18/226604 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/06 (20130101) C22B 5/00 (20130101) Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/06 (20130101) Original (OR) Class C25C 7/02 (20130101) C25C 7/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055490 | Simpson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Garth Jason Simpson (West Lafayette, Indiana); Andreas C. Geiger (Columbia City, Indiana) |
| ABSTRACT | Methods for measuring diffusion in a medium. One method includes dissolving a fluorescent sample in a medium, imaging the fluorescent sample with a patterned illumination Fluorescence Recovery After Photobleaching (FRAP) technique, and analyzing a set of microscope images of the photobleached dissolved fluorescent sample with the patterned illumination using a Fourier Transform (FT) FRAP technique. |
| FILED | Monday, August 28, 2023 |
| APPL NO | 18/457175 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6402 (20130101) G01N 21/6408 (20130101) Original (OR) Class G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/365 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055496 | Humphrey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Simon M. Humphrey (Austin, Texas); Bradley J. Holliday (Austin, Texas); Matthew D. Moore (Austin, Texas); Samuel G. Dunning (Washington, District of Columbia) |
| ABSTRACT | Embodiments of the present disclosure pertain to methods of monitoring an environment for the presence of a solvent by: (i) exposing the environment to a luminescent compound, where the relative luminescence emission intensity of the luminescent compound changes upon interaction with the solvent; and (ii) monitoring a change in the relative luminescence emission intensity of the luminescent compound, where the absence of the change indicates the absence of the solvent from the environment, and where the presence of the change indicates the presence of the solvent in the environment. The luminescent compounds include a phosphorous atom with one or more carboxyl groups, where the carboxyl groups are coordinated with one or more metallic ions (e.g., lanthanide ions and yttrium ions). The present disclosure also pertains to sensors for monitoring an environment for the presence of a solvent, where the sensors include one or more of the aforementioned luminescent compounds. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/740135 |
| ART UNIT | 1796 — Optics |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/182 (20130101) C09K 2211/1014 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Original (OR) Class G01N 31/22 (20130101) G01N 2021/7786 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055756 | Srinivasan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Karthik Srinivasan (Minneapolis, Minnesota); Bethanie Joyce Hills Stadler (Shoreview, Minnesota) |
| ABSTRACT | A non-reciprocal phase shift device may include an optical waveguide (e.g., a silicon waveguide) on a substrate; and a magneto-optical cladding layer on the optical waveguide, wherein the magneto-optical cladding layer includes a plurality of segments arranged having alternating magnetization directions aligned transverse to a longitudinal direction of the optical waveguide. |
| FILED | Wednesday, October 14, 2020 |
| APPL NO | 17/768328 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/132 (20130101) Original (OR) Class G02B 6/12004 (20130101) G02B 2006/12061 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/212 (20210101) G02F 1/0955 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057232 | Clifford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Georgia Tech Research Foundation (Atlanta, Georgia) |
| INVENTOR(S) | Gari Clifford (Decatur, Georgia); Ayse Cakmak (Atlanta, Georgia); Amit Shah (Atlanta, Georgia); Erik Reinertsen (Atlanta, Georgia) |
| ABSTRACT | Methods and systems for monitoring of sensor data for processing by machine-learning models to generate event predictions to estimate a risk a medical event are provided. An electronic device or wearable smart device may monitor the output of various sensors to collect data related to a person's activity level, location changes, and communications and may use this information as input to a personalized trained machine-learning model to predict a likelihood of an event. |
| FILED | Thursday, December 05, 2019 |
| APPL NO | 17/295248 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/2431 (20230101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 40/67 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) Original (OR) Class G16H 50/70 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057831 | Vrudhula et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona); The Texas A and M University System (College Station, Texas) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona); The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | Sarma Vrudhula (Chandler, Arizona); Sunil Khatri (College Station, Texas) |
| ABSTRACT | Threshold logic gates using flash transistors are provided. In an exemplary aspect, flash threshold logic (FTL) provides a novel circuit topology for realizing complex threshold functions. FTL cells use floating gate (flash) transistors to realize all threshold functions of a given number of variables. The use of flash transistors in the FTL cell allows a fine-grained selection of weights, which is not possible in traditional complementary metal-oxide-semiconductor (CMOS)-based threshold logic cells. Further examples include a novel approach for programming the weights of an FTL cell for a specified threshold function using a modified perceptron learning algorithm. |
| FILED | Friday, July 10, 2020 |
| APPL NO | 17/626719 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 16/14 (20130101) G11C 16/28 (20130101) G11C 16/0483 (20130101) G11C 16/3404 (20130101) G11C 29/32 (20130101) Pulse Technique H03K 19/0027 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12058030 | Michael et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VMware LLC (Palo Alto, California) |
| ASSIGNEE(S) | VMware LLC (Palo Alto, California) |
| INVENTOR(S) | Nithin Michael (San Francisco, California); Ao Tang (San Francisco, California); Victor de Souza Lima e Silva (San Francisco, California); Thiago Sousa Santos (San Francisco, California); Ning Wu (San Francisco, California); Archit Baweja (San Francisco, California); Ki Suh Lee (San Francisco, California); Yao Wang (San Francisco, California); Andrey Gushchin (San Francisco, California); Sakethnath Are (San Francisco, California) |
| ABSTRACT | A method comprising instantiating virtual routers (VRs) at each of a set of nodes that form a network. Each VR is coupled to the network and to a tenant of the node. The network comprises virtual links in an overlay network provisioned over an underlay network including servers of a public network. The method comprises configuring at least one VR to include a feedback control system comprising at least one objective function that characterizes the network. The method comprises configuring the VR to receive link state data of a set of virtual links of the virtual links, and control routing of a tenant traffic flow of each tenant according to a best route of the network determined by the at least one objective function using the link state data. |
| FILED | Monday, July 17, 2023 |
| APPL NO | 18/222864 |
| ART UNIT | 2465 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 43/0864 (20130101) H04L 43/0876 (20130101) H04L 45/22 (20130101) Original (OR) Class H04L 45/24 (20130101) H04L 45/745 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12058635 | Pelletier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Woods Hole Oceanographic Institution (Woods Hole, Massachusetts) |
| ASSIGNEE(S) | WOODS HOLE OCEANOGRAPHIC INSTITUTION (Woods Hole, Massachusetts) |
| INVENTOR(S) | Leo-Paul Pelletier (Brest, France); Norman Farr (Woods Hole, Massachusetts); Jonathan Ware (Mashpee, Massachusetts); Christopher McRaven (East Falmouth, Massachusetts) |
| ABSTRACT | A system and method enabling precise range estimation and time synchronization between a first object such as a vehicle having a primary communications mechanism and an interconnected first controller, and a second object having a secondary communications mechanism and an interconnected second controller. The primary sends communications into the environment and the secondary receives them; the secondary then sends replies to the primary. The communications have information for determining range between the two objects and for comparing the second object's internal clock with a more accurate clock of the first object. Repeated exchanges of communications between the two objects enables additional precision of range as well as time synchronization information. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/509860 |
| ART UNIT | 2471 — Multiplex and VoIP |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 11/02 (20130101) Wireless Communication Networks H04W 4/023 (20130101) H04W 4/44 (20180201) H04W 56/006 (20130101) H04W 56/0015 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12053762 | Griffin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Michael Brandon Griffin (Denver, Colorado); Matthew Maurice Yung (Denver, Colorado) |
| ABSTRACT | Described herein are catalysts and methods for converting waste biogas (e.g., a mixture of carbon dioxide and methane) into useful products. In some embodiments, the biogas is converted into a highly purified methane, that can be further processed to generate fuel products, including recycled natural gas (RNG) and liquid fuels. The described catalysts and methods may be advantageous over conventional methods, including by reducing catalyst costs, decreasing temperature requirements and/or providing higher purity products by reducing carbon dioxide and carbon monoxide in product streams. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/551968 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/063 (20130101) B01J 23/10 (20130101) B01J 23/755 (20130101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 1/12 (20130101) C07C 2521/06 (20130101) C07C 2523/10 (20130101) C07C 2523/755 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053765 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of New Hampshire (Durham, New Hampshire) |
| ASSIGNEE(S) | University of New Hampshire (Durham, New Hampshire); The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Gonghu Li (Newmarket, New Hampshire); Anatoly Frenkel (Great Neck, New York); Peipei Huang (Dover, New Hampshire); Jiahao Huang (Port Jefferson, New York) |
| ABSTRACT | A composition of a photocatalyst, a method of manufacturing the photocatalyst, and a method of chemically reducing carbon dioxide to carbon monoxide using the photocatalyst under visible-light irradiation is provided. The photocatalyst comprises a transition metal ion and graphitic carbon nitride and includes single metal sites on carbon nitride. Under visible light, the metal sites that are coordinated to nitrogen atoms get activated, without the use of additional ligands, to catalyze the reduction of carbon dioxide to selectively produce carbon monoxide. The photocatalytic reduction of carbon dioxide to carbon monoxide is highly efficient, resulting a turnover number of more than 800 for carbon monoxide production in 2 hours. The composition is useful in converting carbon dioxide into useful chemicals and carbon-based fuels. A functional model of molecular catalysts for efficient carbon dioxide reduction is also present. |
| FILED | Wednesday, June 03, 2020 |
| APPL NO | 16/891442 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/1815 (20130101) Original (OR) Class B01J 35/39 (20240101) B01J 37/04 (20130101) B01J 2231/005 (20130101) B01J 2231/625 (20130101) B01J 2531/845 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/40 (20170801) Heterocyclic Compounds C07D 487/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053810 | Trumble et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Kevin Paul Trumble (West Lafayette, Indiana); Xiaolong Bai (West Lafayette, Indiana); Srinivasan Chandrasekar (West Lafayette, Indiana); James Mann (Avon, Indiana) |
| ABSTRACT | Processes for producing sheet metal products by machining a solid metal body with a cutting tool in a single step to continuously produce a continuous bulk form from material obtained from the solid metal body, and without performing a hot rolling operation thereon, cold rolling the continuous bulk form to produce a sheet metal product. The machining step is a large-strain machining process capable of being directly performed on an as-cast ingot or other solid body to produce a continuous intermediate product that can be directly cold rolled without any intervening hot rolling operation, and optionally without homogenization or annealing. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/681480 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Rolling of Metal B21B 1/26 (20130101) Original (OR) Class Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 8/0236 (20130101) C21D 9/46 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12053906 | Xiao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clemson University Research Foundation (Clemson, South Carolina) |
| ASSIGNEE(S) | Clemson University Research Foundation (Clemson, South Carolina) |
| INVENTOR(S) | Hai Xiao (Clemson, South Carolina); Jianhua Tong (Central, South Carolina); Fei Peng (Clemson, South Carolina); Kyle S. Brinkman (Clemson, South Carolina); Shenglong Mu (Clemson, South Carolina); Jincheng Lei (Clemson, South Carolina); Yuzhe Hong (Clemson, South Carolina); Hua Huang (Clemson, South Carolina); Rajendra Bordia (Seneca, South Carolina) |
| ABSTRACT | A method for fabricating a protonic ceramic energy device includes: coating an electrolyte layer on an anode layer; and densifying the electrolyte layer by a rapid laser reactive sintering (RLRS) process on the electrolyte layer and/or the anode layer to form a half-cell comprising a dense electrolyte and a porous anode. |
| FILED | Wednesday, December 30, 2020 |
| APPL NO | 17/138173 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/402 (20130101) B23K 2103/52 (20180801) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) Manufacture, Shaping, or Supplementary Processes C03B 19/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054520 | Young et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | Eric Jeffrey Young (Berkeley, California); Cheryl A. Kerfeld (Melrose, Minnesota); Daniel Christopher Ducat (Lansing, Michigan) |
| ABSTRACT | Described herein are constructs, compositions and methods for precise in vivo imaging of the structures and dynamics of protein-based scaffolds with and without their designated cargos. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/531183 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/195 (20130101) Original (OR) Class C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054569 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Matthew N. Lee (Los Alamos, New Mexico); Nicholas G. Parra-Vasquez (Los Alamos, New Mexico); Kyle J. Cluff (Los Alamos, New Mexico) |
| ABSTRACT | Disclosed herein are embodiments of a printable composition that can be used to make printed products of a chosen material chemistry that have different levels of porosity within the printed product's structure Also disclosed herein are embodiments of a printed product that has multiple levels of porosity throughout its structure, which can include a macroscale level of porosity, a microscale level of porosity, a nanoscale level of porosity and any combination thereof. These printed products can be made using a 3-D printer and can be made from a single printable composition without the need to add different structural components during the production process. Also disclosed herein are embodiments of a method for making and using a printed product. |
| FILED | Thursday, January 27, 2022 |
| APPL NO | 17/586450 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/00 (20210101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 222/20 (20130101) Original (OR) Class C08F 222/102 (20200201) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 4/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054580 | Jasti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Ramesh Jasti (Eugene, Oregon); Ruth Maust (Eugene, Oregon); Penghao Li (Evanston, Illinois) |
| ABSTRACT | Embodiments of a nanohoop-functionalized polymer and methods of making and using the same are described herein. In particular embodiments, the polymer comprises one or more nanohoops that extend from the polymer backbone. Also described are polymerizable nanohoop monomer embodiments that can be used to make the polymer embodiments. |
| FILED | Monday, June 12, 2023 |
| APPL NO | 18/208671 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/10 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 2365/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054685 | Davis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Ryan Wesley Davis (San Jose, California); Eric Monroe (Waltham, Massachusetts); Joseph Carlson (Castro Valley, California) |
| ABSTRACT | A chemical upgrading of two high-yield fermentation products to produce a novel biofuel with properties desirable for use in internal combustion engines produces a C7 to C22 alkoxyalkanoate corresponding to formula (I): wherein R2 and R1 are alkyl groups independently selected to have 2 to 18 carbon atoms; wherein the R3 group is a C1 to C5 group divalent alkyl group. The alkoxyalkanoate can be used as a neat fuel or blend with biodiesel, diesel, gasoline, ethanol or other fuels. The alkoxyalkanoates have improved cloud point properties over diesel fuels. A method for making the alkoxyalkanoate from a biomass source is also disclosed. |
| FILED | Wednesday, July 15, 2020 |
| APPL NO | 16/929439 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 67/08 (20130101) C07C 67/317 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/02 (20130101) Original (OR) Class C10L 1/19 (20130101) C10L 2200/0484 (20130101) C10L 2290/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054731 | Kozy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PIONEER HI-BRED INTERNATIONAL, INC. (Johnston, Iowa) |
| ASSIGNEE(S) | PIONEER HI-BRED INTERNATIONAL, INC. (Johnston, Iowa) |
| INVENTOR(S) | Heather Kozy (Walnut Creek, California); Jarred Kenneth Oral (Johnston, Iowa); Ute Schellenberger (Palo Alto, California); Jun-Zhi Wei (Johnston, Iowa); Weiping Xie (East Palo Alto, California); Xiaohong Zhong (San Leandro, California); Genhai Zhu (San Jose, California) |
| ABSTRACT | Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity. |
| FILED | Thursday, January 27, 2022 |
| APPL NO | 17/585983 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 47/44 (20130101) Peptides C07K 14/21 (20130101) C07K 14/24 (20130101) C07K 14/245 (20130101) C07K 2319/00 (20130101) C07K 2319/21 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8242 (20130101) C12N 15/8286 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054845 | Tripathy |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Prabhat K. Tripathy (Idaho Falls, Idaho) |
| ABSTRACT | A metal coated article includes a platinum-group metal region adjacent a refractory metal region, which is adjacent a substrate comprising an inorganic material. A refractory metal carbide layer is adjacent the substrate and the refractory metal layer is adjacent the refractory metal carbide layer. The platinum-group metal region comprises a refractory metal/platinum-group metal layer and a platinum-group metal layer. Related methods are also disclosed. |
| FILED | Wednesday, December 21, 2022 |
| APPL NO | 18/069386 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 5/10 (20130101) Original (OR) Class C25D 5/50 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/12875 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054852 | Mutalik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Vivek K. Mutalik (Albany, California); Adam Deutschbauer (Berkeley, California); Adam P. Arkin (San Francisco, California); Pavel Novichkov (Walnut Creek, California) |
| ABSTRACT | Disclosed herein are barcoded expression libraries comprising a plurality of expression vectors, wherein each expression vector comprises a nucleic acid fragment flanked by a first barcode and a second barcode. Further disclosed herein are methods of making the barcoded expression libraries and methods of conducting functional analysis using the barcoded expression libraries. |
| FILED | Monday, July 31, 2017 |
| APPL NO | 15/665226 |
| ART UNIT | 1675 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055081 | Hoye et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | CUMMINS INC. (Columbus, Indiana) |
| INVENTOR(S) | Robert F. Hoye (Columbus, Indiana); Victor Matthew Penrod (Columbus, Indiana) |
| ABSTRACT | A dual-wall integrated flange joint is provided. The integrated flange joint includes an inner wall having at least one inlet and at least one outlet, a flange extending radially outward from the inlet of the inner wall, and a collar extending from the flange in the direction of the inner wall and surrounding at least a portion of the inner wall. The integrated flange joint is formed of a single piece of material. Also, the collar at least partially defines an outer wall, and a volume between the collar and the inner wall at least partially defines an airgap. |
| FILED | Wednesday, May 15, 2019 |
| APPL NO | 17/054577 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 13/102 (20130101) Original (OR) Class F01N 13/107 (20130101) F01N 13/1844 (20130101) F01N 2450/22 (20130101) F01N 2450/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055438 | Rinaldi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Matteo Rinaldi (Boston, Massachusetts); Vageeswar Rajaram (Boston, Massachusetts); Zhenyun Qian (Boston, Massachusetts); Sungho (Ryan) Kang (Cambridge, Massachusetts); Sila Deniz Calisgan (Boston, Massachusetts); Antea Risso (Cambridge, Massachusetts) |
| ABSTRACT | Ultra-low power methods and sensor devices are provided for determining the presence and magnitude of electromagnetic radiation or other signals. The sensor devices and methods provide both qualitative and quantitative analyses and can be deployed in remote locations for continuous monitoring over years without requiring a replacement power supply. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 17/729214 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/42 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055500 | Jau |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Yuan-Yu Jau (Albuquerque, New Mexico) |
| ABSTRACT | A method and corresponding apparatus are provided for measuring neutron spin precession in an electric field with high sensitivity suitable for practical applications in non-destructive testing, imaging, and the like. Production of a neutron beam with a polarization vector P is followed by transmitting the spin-polarized neutron beam through a sample region in which there is a target generating an electric field, polarization-analyzing the transmitted neutron beam with an analyzing direction orthogonal to P, detecting an intensity of the polarization-analyzed neutron beam; and mapping the detected neutron-beam intensity to a field-strength value for the target electric field. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 17/740504 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) Original (OR) Class G01N 23/09 (20130101) G01N 2223/04 (20130101) G01N 2223/40 (20130101) G01N 2223/505 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057304 | Ovchinnikova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Olga S. Ovchinnikova (Oak Ridge, Tennessee); Anton V. Ievlev (Oak Ridge, Tennessee); Matthias Lorenz (Toronto, Canada); Nikolay Borodinov (Newtown, Pennsylvania); Steven T. King (Hempstead, New York) |
| ABSTRACT | Machine learning approach can combine mass spectral imaging (MSI) techniques, one with low spatial resolution but intact molecular spectra and the other with nanometer spatial resolution but fragmented molecular signatures, to predict molecular MSI spectra with submicron spatial resolution. The machine learning approach can perform transformations on the spectral image data of the two MSI techniques to reduce dimensionality, and using a correlation technique, find relationships between the transformed spectral image data. The determined relationships can be used to generate MSI spectra of desired resolution. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/337919 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/2258 (20130101) G01N 2223/07 (20130101) G01N 2223/40 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) G06N 20/00 (20190101) Electric Discharge Tubes or Discharge Lamps H01J 49/0004 (20130101) H01J 49/0036 (20130101) Original (OR) Class H01J 49/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057555 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); U.S. ARMY RESEARCH LABORATORY (Adelphi, Maryland) |
| ASSIGNEE(S) | University of Maryland (, None); U.S. Army Research Laboratory (, None) |
| INVENTOR(S) | Chunsheng Wang (Silver Spring, Maryland); Kang Xu (Potomac, Maryland); Liumin Suo (Greenbelt, Maryland) |
| ABSTRACT | The present invention is directed to a hybrid high voltage aqueous electrolyte battery that combines Ni/Mg2NiH4 and Mg-ion rechargeable battery chemistries. The hybrid aqueous electrolyte battery can be used for plug-in hybrid electrical vehicles and electric vehicles. |
| FILED | Wednesday, January 28, 2015 |
| APPL NO | 15/114997 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/48 (20130101) H01M 4/466 (20130101) H01M 4/485 (20130101) H01M 10/36 (20130101) Original (OR) Class H01M 2200/20 (20130101) H01M 2220/20 (20130101) H01M 2300/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057556 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Kang Xu (Potomac, Maryland); Arthur Von Wald Cresce (Beltsville, Maryland); Oleg A. Borodin (Laurel, Maryland); Chunsheng Wang (Silver Spring, Maryland); Liumin Suo (Greenbelt, Maryland) |
| ABSTRACT | The present invention is directed to aqueous and hybrid aqueous electrolytes that comprise a lithium salt. The present invention is also directed to methods of making the electrolytes and methods of using the electrolytes in batteries and other electrochemical technologies. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346673 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/5815 (20130101) H01M 4/5825 (20130101) H01M 10/26 (20130101) H01M 10/36 (20130101) Original (OR) Class H01M 10/056 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0002 (20130101) H01M 2300/0014 (20130101) H01M 2300/0025 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12057613 | Krueger |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Daniel Scott Krueger (Kansas City, Missouri) |
| ABSTRACT | Waveguides and methods for manufacturing a waveguide that include forming a first channel in a first layer of dielectric material, the first channel comprising one or more walls; forming a second channel in a second layer of dielectric material, the second channel comprising one or more walls; depositing electrically conductive material on the one or more walls of the first channel; depositing electrically conductive material on the one or more walls of the second channel; arranging the first layer adjacent to the second layer to form a stack with the first channel axially aligned with and facing the second channel; and heating the stack so that the conductive material on the one or more walls of the first channel and the conductive material on the one or more walls of the second channel connect to form the waveguide. |
| FILED | Thursday, June 08, 2023 |
| APPL NO | 18/331737 |
| ART UNIT | 2843 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 3/16 (20130101) H01P 3/121 (20130101) Original (OR) Class H01P 11/002 (20130101) H01P 11/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12058032 | Roweth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| INVENTOR(S) | Duncan Roweth (Bristol, United Kingdom); Robert L. Alverson (Seattle, Washington); Edwin L. Froese (Burnaby, Canada) |
| ABSTRACT | Systems and methods of routing a data communication across a network having a plurality switches are provided by monitoring the operation of the plurality of global links to determine which of the plurality of global links provide working paths. A routing table indicative of a status for the plurality of links is maintained, where the routing table provides weighting for each of the working paths. When routing, a link using a weighted pseudo-random selection from the choices available in the routing table is selected. Routing along one of the working paths commensurate with the selected link is performed, and the weighting is updated based upon the operation of the plurality of links. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/594682 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) G06F 9/546 (20130101) G06F 12/0862 (20130101) G06F 12/1036 (20130101) G06F 12/1063 (20130101) G06F 13/14 (20130101) G06F 13/16 (20130101) G06F 13/28 (20130101) G06F 13/385 (20130101) G06F 13/1642 (20130101) G06F 13/1673 (20130101) G06F 13/1689 (20130101) G06F 13/4022 (20130101) G06F 13/4068 (20130101) G06F 13/4221 (20130101) G06F 15/17331 (20130101) G06F 2212/50 (20130101) G06F 2213/0026 (20130101) G06F 2213/3808 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0083 (20130101) H04L 43/10 (20130101) H04L 43/0876 (20130101) H04L 45/02 (20130101) H04L 45/16 (20130101) H04L 45/20 (20130101) H04L 45/021 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/028 (20130101) H04L 45/28 (20130101) Original (OR) Class H04L 45/38 (20130101) H04L 45/42 (20130101) H04L 45/46 (20130101) H04L 45/70 (20130101) H04L 45/122 (20130101) H04L 45/123 (20130101) H04L 45/125 (20130101) H04L 45/566 (20130101) H04L 45/745 (20130101) H04L 45/7453 (20130101) H04L 47/11 (20130101) H04L 47/12 (20130101) H04L 47/18 (20130101) H04L 47/20 (20130101) H04L 47/22 (20130101) H04L 47/24 (20130101) H04L 47/30 (20130101) H04L 47/32 (20130101) H04L 47/34 (20130101) H04L 47/39 (20130101) H04L 47/52 (20130101) H04L 47/76 (20130101) H04L 47/80 (20130101) H04L 47/122 (20130101) H04L 47/323 (20130101) H04L 47/621 (20130101) H04L 47/626 (20130101) H04L 47/629 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) H04L 47/2466 (20130101) H04L 47/2483 (20130101) H04L 47/6235 (20130101) H04L 47/6275 (20130101) H04L 49/15 (20130101) H04L 49/30 (20130101) H04L 49/90 (20130101) H04L 49/101 (20130101) H04L 49/3009 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) H04L 49/9005 (20130101) H04L 49/9021 (20130101) H04L 49/9036 (20130101) H04L 49/9047 (20130101) H04L 67/1097 (20130101) H04L 69/22 (20130101) H04L 69/28 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12053767 | Mireles et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The National Aeronautics and Space Administration (Washington, District of Columbia); EOS North America (Novi, Michigan) |
| ASSIGNEE(S) | EOS North America (Novi, Michigan); The National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Omar Mireles (Huntsville, Alabama); Zachary Jones (Montreal, Canada); Maryna Ienina (Pflugerville, Texas); Ankit Saharan (Pflugerville, Texas) |
| ABSTRACT | In one aspect, a method for manufacturing a lattice structure for use as a propulsion catalyst includes: (a) providing a powder bed of one or more metal powder materials, (b) heating a portion of the powder bed to a temperature sufficient to melt the one or more metal powder materials, (c) forming a layer of the lattice structure, wherein the layer is formed by melting the one or more metal powder materials in a predefined pattern, (d) constructing the lattice structure, wherein the lattice structure is constructed by repeating steps (a)-(c) for each of a plurality of layers of the lattice structure until the lattice structure is constructed, and (e) removing excess materials from the constructed lattice structure. |
| FILED | Thursday, August 04, 2022 |
| APPL NO | 17/803491 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/56 (20240101) B01J 37/0018 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12054294 | Woods et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sierra Space Corporation (Broomfield, Colorado) |
| ASSIGNEE(S) | Sierra Space Corporation (Broomfield, Colorado) |
| INVENTOR(S) | Grant Robert Woods (Littleton, Colorado); Jeffrey S. Hickerson (Erie, Colorado); Charles Ralph Sandy (Camden, Delaware) |
| ABSTRACT | Methods, devices, and systems are described for a bracket fixture for securing a load to a soft goods layer in a space habitat. The bracket fixture includes a base having a plurality of sides, the plurality of sides having a pin parallel to its respective side, and an aperture between the pin and the respective side. The bracket fixture further includes a protrusion extending from the base, the protrusion including a fixture element. |
| FILED | Monday, April 11, 2022 |
| APPL NO | 17/717989 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/60 (20130101) Original (OR) Class B64G 1/2227 (20230801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055427 | Blackmon |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in Huntsville (Huntsville, Alabama) |
| ASSIGNEE(S) | Board of Trustees of the University of Alabama for and on behalf of the University of Alabama in Huntsville (Huntsville, Alabama) |
| INVENTOR(S) | James B. Blackmon (Brownsboro, Alabama) |
| ABSTRACT | The present disclosure generally pertains to devices and methods for determining propellant mass based on average measurements irrespective of the fluid orientation in a fuel tank. The device is useful in detecting fuel levels in tanks where the fuel is in motion, for instance in aircraft (i.e., undergoing varying acceleration maneuvers) or spacecraft (i.e., a microgravity environment). The devices and methods can also be used for determining the liquid in a surface tension screen liquid acquisition device (LAD), and particularly, the incipient breakdown as gas bubbles enter or are formed inside the LAD as the screen dries or heat transfer induces vaporization. The same basic electrode configuration can be used to stir the liquid to reduce thermal stratification and condense vapor bubbles. |
| FILED | Wednesday, September 23, 2020 |
| APPL NO | 17/029719 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 23/263 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/228 (20130101) G01N 37/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 12053491 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seattle, Washington) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seattle, Washington) |
| INVENTOR(S) | Yvonne Y. Chen (Los Angeles, California); Eugenia Zah (Los Angeles, California); Michael C. Jensen (Seattle, Washington) |
| ABSTRACT | A CD19-OR-CD20 chimeric antigen receptor (CAR) protein construct is provided. Also provided are nucleic acids encoding the CD19-OR-CD20 CAR; and methods of use, e.g. in the treatment of B cell malignancies. The CD19-OR-CD20 CAR of the invention is a bispecific CAR that can trigger T-cell activation upon detection of either CD19 or CD20 (or both). It is a single molecule that confers two-input recognition capability upon human T cells engineered to stably express this CAR. |
| FILED | Friday, August 25, 2023 |
| APPL NO | 18/238210 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70596 (20130101) C07K 16/46 (20130101) C07K 16/2803 (20130101) C07K 16/2887 (20130101) C07K 2317/31 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12055495 | Guadiuso et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Rosalba Guadiuso (Mola di Bari, Italy); Noureddine Melikechi (Westford, Massachusetts); Weiming Xia (Boston, Massachusetts) |
| ABSTRACT | Diagnosing a pathology using LIBS and biological fluids includes focusing light on to a sample on a substrate to cause ablation of the sample and formation of a plasma, collecting optical emission from the plasma, and providing the optical emission to a spectroscopic acquisition component that provides information on spectral data of the plasma. The spectral data is provided to a machine learning algorithm to diagnose a pathology in the sample, where the algorithm is trained on a training set that includes spectral features in a difference spectrum derived from differences between a first LIBS optical emission spectrum collected from one or more samples of the biological fluid that have the pathology or known progress of the pathology and a second LIBS optical emission spectrum collected from one or more samples of the predetermined biological fluid that do not have the pathology or the known progress of the pathology. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 17/305901 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/718 (20130101) Original (OR) Class G01N 33/487 (20130101) G01N 2201/129 (20130101) Computer Systems Based on Specific Computational Models G06N 5/022 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 12056044 | Underwood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| INVENTOR(S) | Keith D. Underwood (Powell, Tennessee); Robert L. Alverson (Seattle, Washington); Christopher Michael Brueggen (Allen, Texas) |
| ABSTRACT | A system, method, and apparatus are provided to facilitate data structures for a datatype engine and provide inline compaction. The system receives, by a network interface card (NIC), a command to read data from a host memory, wherein the command indicates a datatype. The system generates a plurality of read requests comprising offsets from a base address and corresponding lengths based on the datatype. The system issues the plurality of read requests to the host memory to obtain the data from the host memory. The system obtains a byte-mask descriptor corresponding to the datatype. The system performs, based on the obtained data and the byte-mask descriptor, on-the-fly compaction of the obtained data, thereby allowing the NIC to return a requested subset of the obtained data. |
| FILED | Friday, October 28, 2022 |
| APPL NO | 17/976730 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0659 (20130101) G06F 3/0673 (20130101) G06F 12/0207 (20130101) Original (OR) Class G06F 2212/1016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12058032 | Roweth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hewlett Packard Enterprise Development LP (Houston, Texas) |
| ASSIGNEE(S) | Hewlett Packard Enterprise Development LP (Spring, Texas) |
| INVENTOR(S) | Duncan Roweth (Bristol, United Kingdom); Robert L. Alverson (Seattle, Washington); Edwin L. Froese (Burnaby, Canada) |
| ABSTRACT | Systems and methods of routing a data communication across a network having a plurality switches are provided by monitoring the operation of the plurality of global links to determine which of the plurality of global links provide working paths. A routing table indicative of a status for the plurality of links is maintained, where the routing table provides weighting for each of the working paths. When routing, a link using a weighted pseudo-random selection from the choices available in the routing table is selected. Routing along one of the working paths commensurate with the selected link is performed, and the weighting is updated based upon the operation of the plurality of links. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/594682 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/505 (20130101) G06F 9/546 (20130101) G06F 12/0862 (20130101) G06F 12/1036 (20130101) G06F 12/1063 (20130101) G06F 13/14 (20130101) G06F 13/16 (20130101) G06F 13/28 (20130101) G06F 13/385 (20130101) G06F 13/1642 (20130101) G06F 13/1673 (20130101) G06F 13/1689 (20130101) G06F 13/4022 (20130101) G06F 13/4068 (20130101) G06F 13/4221 (20130101) G06F 15/17331 (20130101) G06F 2212/50 (20130101) G06F 2213/0026 (20130101) G06F 2213/3808 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0083 (20130101) H04L 43/10 (20130101) H04L 43/0876 (20130101) H04L 45/02 (20130101) H04L 45/16 (20130101) H04L 45/20 (20130101) H04L 45/021 (20130101) H04L 45/22 (20130101) H04L 45/24 (20130101) H04L 45/028 (20130101) H04L 45/28 (20130101) Original (OR) Class H04L 45/38 (20130101) H04L 45/42 (20130101) H04L 45/46 (20130101) H04L 45/70 (20130101) H04L 45/122 (20130101) H04L 45/123 (20130101) H04L 45/125 (20130101) H04L 45/566 (20130101) H04L 45/745 (20130101) H04L 45/7453 (20130101) H04L 47/11 (20130101) H04L 47/12 (20130101) H04L 47/18 (20130101) H04L 47/20 (20130101) H04L 47/22 (20130101) H04L 47/24 (20130101) H04L 47/30 (20130101) H04L 47/32 (20130101) H04L 47/34 (20130101) H04L 47/39 (20130101) H04L 47/52 (20130101) H04L 47/76 (20130101) H04L 47/80 (20130101) H04L 47/122 (20130101) H04L 47/323 (20130101) H04L 47/621 (20130101) H04L 47/626 (20130101) H04L 47/629 (20130101) H04L 47/762 (20130101) H04L 47/781 (20130101) H04L 47/2441 (20130101) H04L 47/2466 (20130101) H04L 47/2483 (20130101) H04L 47/6235 (20130101) H04L 47/6275 (20130101) H04L 49/15 (20130101) H04L 49/30 (20130101) H04L 49/90 (20130101) H04L 49/101 (20130101) H04L 49/3009 (20130101) H04L 49/3018 (20130101) H04L 49/3027 (20130101) H04L 49/9005 (20130101) H04L 49/9021 (20130101) H04L 49/9036 (20130101) H04L 49/9047 (20130101) H04L 67/1097 (20130101) H04L 69/22 (20130101) H04L 69/28 (20130101) H04L 69/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 12054720 | Ford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University park, Pennsylvania) |
| INVENTOR(S) | Suzanne Ford (State College, Pennsylvania); Elizabeth McGraw (State College, Pennsylvania) |
| ABSTRACT | Provided are compositions and methods for inhibiting transmission of viruses that use mosquitoes as vectors, such as dengue (DENV), Zika (ZIKV) and Chikungunya (CHIKV) viruses. Inhibiting transmission includes reducing viral load of the virus in mosquitoes. The viral load is reduced in mosquitoes that are exposed to the virus by introducing into the mosquitoes or mosquito larvae one or more agents that can participate in RNA interference (RNAi) of expression of one or more mosquito genes, such as alpha-mannosidase 2, or Cadherin87A, or a combination thereof. Also provided are modified mosquitoes or mosquito larvae that comprise the RNAi agents. The modified mosquitoes can be released into a population of unmodified mosquitoes to inhibit transmission of the virus between mammalian hosts. Also provided are compositions comprising an RNAi agent or an expression vector that encodes the RNAi agent for use in the described methods. |
| FILED | Thursday, August 29, 2019 |
| APPL NO | 17/272269 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2320/31 (20130101) Enzymes C12Y 302/01024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 12056655 | Dixon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Robert E. Dixon (Washington, District of Columbia); Ryan Luckay (Washington, District of Columbia) |
| ABSTRACT | A receptacle for detecting delivery and retrieval events has a door sensor, an item sensor, a scanner, and a control unit for operating the sensors, and transmitting the sensor information for processing and analysis. A system can determine whether an event was a delivery or retrieval event based on sensor information and item tracking information. A system can further include an item configured to interact with a computing device. |
| FILED | Thursday, February 09, 2023 |
| APPL NO | 18/166912 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Household or Table Equipment A47G 29/141 (20130101) A47G 2029/145 (20130101) A47G 2029/146 (20130101) A47G 2029/149 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) G06K 19/06028 (20130101) G06K 2019/06253 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0836 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 12057429 | Lopez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
| INVENTOR(S) | Aurelio Lopez (Malibu, California); Peter Brewer (Westlake Village, California); Partia Naghibi Mahmoudabadi (Thousand Oaks, California); Erik Daniel (Malibu, California); Tahir Hussain (Malibu, California) |
| ABSTRACT | A method for bonding two confronting electronic devices together wherein the two electronic devices are initially temporarily coupled together using a room temperature process with a plurality of knife-edge microstructures on at least a first one of the electronic devices engaging portions of the a second one of the electronic devices. The room temperature process involves applying a relatively low compressive force or pressure between the two electronic devices compared to the forces or pressures used in convention flip-chip bonding. The first one of the electronic devices and the second one of the electronic devices also have traditional contact pads that are spaced from each other by a standoff distance when the devices are initially coupled together using the room temperature process. This allows for inspection of the two electronic devices while they are initially temporarily coupled together. In need be, the two can be separated at this stage for re-work After passing inspection, a relatively higher compressive force or pressure is applied between the two electronic devices to cause the standoff distance to decrease to zero and for the contact pads confronting each other on the confronting two electronic devices to weld thereby permanently bonding the two electronic devices together. |
| FILED | Wednesday, June 23, 2021 |
| APPL NO | 17/356387 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 24/13 (20130101) H01L 24/14 (20130101) H01L 24/16 (20130101) H01L 24/81 (20130101) Original (OR) Class H01L 2224/13013 (20130101) H01L 2224/13016 (20130101) H01L 2224/13144 (20130101) H01L 2224/13466 (20130101) H01L 2224/14051 (20130101) H01L 2224/16057 (20130101) H01L 2224/80201 (20130101) H01L 2224/80986 (20130101) H01L 2224/81053 (20130101) H01L 2224/81193 (20130101) H01L 2224/81203 (20130101) H01L 2224/81379 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, August 06, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240806.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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