FedInvent™ Patents
Patent Details for Tuesday, August 13, 2024
This page was updated on Tuesday, August 13, 2024 at 05:27 AM GMT
Department of Health and Human Services (HHS)
| US 12058996 | Toner et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mehmet Toner (Charlestown, Massachusetts); Mustafa Korkut Uygun (Newton, Massachusetts); Shannon N. Tessier (Framingham, Massachusetts); Shannon L. Stott (Stoneham, Massachusetts); Lindong Weng (Arlington, Massachusetts); Reinier Johan De Vries (Boston, Massachusetts); Casie A. Pendexter (Rockland, Massachusetts); Stephanie E J Cronin (Boston, Massachusetts) |
| ABSTRACT | This disclosure is related to methods of preserving biological samples, organs, and organisms. This disclosure is based, at least in part, on the discovery that in the presence of heterogenous extracellular ice, endothelial cells have improved attachment and viability after preservation, and particularly by uniformly nucleating ice across the microvasculature using ice nucleating agents, the chance of intracelluar ice formation can be significantly reduced. |
| FILED | Thursday, June 14, 2018 |
| APPL NO | 16/622457 |
| ART UNIT | 1638 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Original (OR) Class A01N 1/0294 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059254 | Kintz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Profusa, Inc. (Emeryville, California) |
| ASSIGNEE(S) | Profusa, Inc. (Emeryville, California) |
| INVENTOR(S) | Gregory J. Kintz (Santa Cruz, California); William McMillan (La Honda, California); Natalie Wisniewski (San Francisco, California) |
| ABSTRACT | An optical device is used to monitor an implant embedded in the tissue of a mammal (e.g., under the skin). The implant receives excitation light from the optical device and emits light that is detected by the optical device, including an analyte-dependent optical signal. Scatter and absorption properties of tissue change over time due to changes in hydration, blood perfusion and oxygenation. The optical device has an arrangement of light sources, filters and detectors to transmit excitation light within excitation wavelength ranges and to measure emitted light within detection wavelengths. Changes in scattering and absorption of light in the tissue, such as diffuse reflectance, are monitored. The light sources, filters and detectors may also be used to monitor autofluorescence in the tissue to correct autofluorescence background. |
| FILED | Monday, October 04, 2021 |
| APPL NO | 17/493451 |
| ART UNIT | 3798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1459 (20130101) Original (OR) Class A61B 5/7203 (20130101) A61B 5/14532 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059403 | Sah |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Rajan Sah (Iowa City, Iowa) |
| ABSTRACT | The invention provides the use of SWELL1 inhibitors and modulators for therapeutic use, e.g., to treat obesity and type 2 diabetes. |
| FILED | Friday, August 04, 2017 |
| APPL NO | 16/322709 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) Original (OR) Class A61K 31/138 (20130101) A61K 31/192 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059407 | Murthy et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Niren Murthy (Berkeley, California); Joachim Justad Roeise (Berkeley, California); Chung Hak Taing (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Niren Murthy (Berkeley, California); Joachim Justad Roeise (Berkeley, California); Chung Hak Taing (Berkeley, California) |
| ABSTRACT | The present disclosure provides endosomal disruptors, which are useful for facilitating delivery of a macromolecule to the cytoplasm of a cell. The present disclosure provides compositions comprising an endosomal disruptor and a macromolecule. The present disclosure provides methods of delivering a macromolecule to the cytoplasm of a cell. |
| FILED | Monday, December 03, 2018 |
| APPL NO | 16/766226 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/192 (20130101) A61K 31/4192 (20130101) Original (OR) Class A61K 38/465 (20130101) A61K 47/61 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059413 | Carter et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York); THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Carol Carter (Huntington, New York); Lorna Erlich (Shoreham, New York); Nico Tjandra (Bethesda, Maryland); Madeleine Davison (Washington, District of Columbia) |
| ABSTRACT | The present invention provides a method of inhibiting release of a virus from a cell, comprising contacting the cell with a compound that binds an ubiquitin E2 variant (UEV) domain of a cellular polypeptide, or fragment thereof, with an affinity sufficient to inhibit or disrupt the binding of the cellular polypeptide, or fragment thereof, to ubiquitin. |
| FILED | Monday, October 30, 2017 |
| APPL NO | 16/342695 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4439 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059418 | Desai |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Sanjay A. Desai (Potomac, Maryland) |
| ABSTRACT | The invention provides methods of treating or preventing malaria comprising administering to an animal an effective amount of a compound of formula I: Q-Y—R1—R2 (I), wherein Q, Y, R1, and R2 are as described herein. Methods of inhibiting a plasmodial surface anion channel of a parasite in an animal are also provided. The invention also provides pharmaceutical compositions comprising a compound represented by formula I in combination with any one or more compounds represented by formulas II, V, and VI. Use of the pharmaceutical compositions for treating or preventing malaria or for inhibiting a plasmodial surface anion channel in animals including humans are also provided. Also provided by the invention are clag3 amino acid sequences and related nucleic acids, vectors, host cells, populations of cells, antibodies, and pharmaceutical compositions. |
| FILED | Tuesday, December 08, 2020 |
| APPL NO | 17/115317 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/42 (20130101) A61K 31/50 (20130101) A61K 31/422 (20130101) A61K 31/423 (20130101) A61K 31/427 (20130101) A61K 31/433 (20130101) A61K 31/433 (20130101) A61K 31/437 (20130101) A61K 31/495 (20130101) A61K 31/496 (20130101) A61K 31/498 (20130101) A61K 31/501 (20130101) Original (OR) Class A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/554 (20130101) A61K 31/554 (20130101) A61K 31/4355 (20130101) A61K 31/4439 (20130101) A61K 31/4741 (20130101) A61K 39/015 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Heterocyclic Compounds C07D 239/84 (20130101) C07D 241/44 (20130101) C07D 263/57 (20130101) C07D 277/54 (20130101) C07D 281/16 (20130101) C07D 409/04 (20130101) C07D 409/14 (20130101) C07D 413/14 (20130101) C07D 417/06 (20130101) C07D 491/048 (20130101) C07D 498/04 (20130101) C07D 513/04 (20130101) Peptides C07K 14/445 (20130101) C07K 16/205 (20130101) C07K 2319/21 (20130101) C07K 2319/43 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059426 | Marcantonio et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARMGO Pharma, Inc. (Ardsley, New York) |
| ASSIGNEE(S) | ARMGO Pharma, Inc. (Ardsley, New York) |
| INVENTOR(S) | Eugene E. Marcantonio (Tenafly, New Jersey); Mette Uhre Anby (Frederiksberg, Denmark); Jérôme Binet (Saint Denis en Val, France) |
| ABSTRACT | The present disclosure provides a modified-release pharmaceutical composition comprising 4-[(7-methoxy-2,3-dihydro-1,4-benzothiazepin-4(5H)yl)methyl]benzoic acid hemifumarate, and a pharmaceutically-acceptable excipient. The present disclosure methods of treating conditions associated with RyRs, including, for example, cardiac disorder or disease, a musculoskeletal disorder or disease, cancer associated muscle weakness, malignant hyperthermia, and diabetes. |
| FILED | Thursday, July 13, 2023 |
| APPL NO | 18/221784 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/2866 (20130101) A61K 9/2886 (20130101) A61K 31/554 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059429 | Kelly |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Kimberly A. Kelly (Crozet, Virginia) |
| ABSTRACT | Provided are compositions and methods for use of hornerin-binding molecules, including peptides and antibodies. In some embodiments, the presently disclosed subject matter provides compositions that include horning-binding molecules, including but not limited to peptides, uses for the disclosed compositions, including in methods for treating tumors, methods for increasing the survival of subject with tumor, methods for suppressing tumor growth in subjects, methods for reducing tumor vascularity in subjects, methods for treating diseases, disorders, and/or conditions associated with undesirable hornerin expression; methods for modulating hornerin biological activities, methods for imaging cells, tissues, and/or organs that expresses hornerin, and methods for delivering active agents to cells, tissues, and/or organ that expresses hornerin. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/572234 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) C07K 16/30 (20130101) C07K 16/2863 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059434 | Kalinski |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Pawel Kalinski (East Aurora, New York) |
| ABSTRACT | Provided herein are ST-αDC1 and populations of those cells, methods for making ST-αDC1 and populations of those cells, and methods for using ST-αDC1 and populations of those cells for the treatment of cancer, precancerous conditions and chronic infections. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 16/488702 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0639 (20130101) C12N 2501/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059435 | Morrison |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltmore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Brett Morrison (Baltimore, Maryland) |
| ABSTRACT | Provided herein are methods and compositions for increasing nerve regeneration activity of a macrophage, and for inducing and accelerating nerve regeneration of an injured or damaged nerve. Methods and compositions provided herein include upregulating the expression of an MCT1 gene in a macrophage. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 17/412127 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Peptides C07K 14/47 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059454 | Daniell et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida) |
| INVENTOR(S) | Henry Daniell (Media, Pennsylvania); Qiuhong Li (Gainesville, Florida); Mohan K. Raizada (Alachua, Florida) |
| ABSTRACT | Emerging evidence indicates that diminished activity of the vasoprotective axis of the renin-angiotensin system, constituting angiotensin converting enzyme2 (ACE2) and its enzymatic product, angiotensin-(1-7) [Ang-(1-7)] contribute to pulmonary hypertension (PH). However, clinical success for long-term delivery of ACE2 or Ang-(1-7) would require stability and ease of administration to increase patient compliance. Chloroplast expression of therapeutic proteins enables their bioencapsulation within plant cells to protect from acids and gastric enzymes; fusion to a transmucosal carrier facilitates effective systemic absorption. Oral feeding of rats with bioencapsulated ACE2 or Ang-(1-7) attenuated monocrotaline (MCT)-induced increase in right ventricular systolic pressure, decreased pulmonary vessel wall thickness and improved right heart function in both prevention and reversal protocols. Furthermore, combination of ACE2 and Ang-(1-7) augmented the beneficial effects against cardio-pulmonary pathophysiology induced by MCT administration. Experiments have also been performed which indicate that this approach is also suitable for the treatment or inhibition of experimental uveitis and autoimmune uveoretinitis These studies provide proof-of-concept for a novel low-cost oral ACE2 or Ang-(1-7) delivery system using transplastomic technology for pulmonary and ocular disease therapeutics. |
| FILED | Wednesday, February 02, 2022 |
| APPL NO | 17/591151 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/0053 (20130101) A61K 9/1664 (20130101) A61K 9/5063 (20130101) A61K 36/23 (20130101) A61K 36/28 (20130101) A61K 36/31 (20130101) A61K 38/22 (20130101) A61K 38/164 (20130101) A61K 38/4813 (20130101) Original (OR) Class A61K 47/65 (20170801) A61K 47/6415 (20170801) Peptides C07K 14/28 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) C12N 15/8214 (20130101) C12N 15/8257 (20130101) Enzymes C12Y 304/15001 (20130101) C12Y 304/17023 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059476 | Green et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Jordan J. Green (Baltimore, Maryland); Jonathan Schneck (Blatimore, Maryland); Alyssa K. Galaro (Baltimore, Maryland); Randall A. Meyer (Baltimore, Maryland); John W. Hickey (Baltimore, Maryland); Kelly Rhodes (Baltimore, Maryland) |
| ABSTRACT | The present invention provides biodegradable, biomimetic particles for interacting with cells, including immune cells. In various embodiments, the particles comprise a polymer blend comprising a polyester, such as poly(lactic-co-glycolic acid) (PLGA) and a polyamine, such as poly(beta-amino ester) (PBAE). The particles further comprise, on their surface, one or more ligands for one or more cell surface receptor(s) or cell surface molecule(s). In some embodiments, the cell surface receptor or cell surface molecule is on an immune cell, such as a lymphocyte (T cell or B cell), natural killer cell, dendritic cell, or other cell of the immune system or tumor microenvironment. |
| FILED | Wednesday, October 10, 2018 |
| APPL NO | 16/754951 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/62 (20170801) A61K 47/6849 (20170801) A61K 47/6927 (20170801) Original (OR) Class Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 16/2878 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059480 | Ganesh et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Karuna Ganesh (New York, New York); Manuel Valiente (Madrid, Spain); Joan Massague (New York, New York) |
| ABSTRACT | The present invention relates to methods and compositions for inhibiting metastatic spread of cancer and/or inhibiting progression of pre-existing metastatic disease in a subject using L1CAM inhibition. |
| FILED | Monday, October 10, 2022 |
| APPL NO | 18/045357 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/519 (20130101) A61K 45/06 (20130101) A61K 48/0016 (20130101) A61K 48/0066 (20130101) Original (OR) Class A61K 48/0083 (20130101) A61K 48/0091 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059482 | Bogyo et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Matthew S. Bogyo (Redwood City, California); Martijn Verdoes (Nijmegen, Netherlands) |
| ABSTRACT | Activity-based probe compounds for use in labeling a cysteine protease are provided. The compounds are targeted to the protease through a specific targeting element. The compounds additionally include a detectable element, such as a fluorescent label, a radiolabel, or a chelator. In some cases, the compounds additionally include a quenching element that is released upon reaction with the protease. Also provided are compositions comprising the compounds and methods for using the compounds, for example in labeling a protease in an animal and in visualizing a tumor in an animal. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/127754 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0034 (20130101) A61K 49/0052 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059499 | Heath et al. |
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| FUNDED BY |
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| APPLICANT(S) | PLUMB PHARMACEUTICALS, INC. (Madison, Wisconsin) |
| ASSIGNEE(S) | PLUMB PHARMACEUTICALS, INC. (Madison, Wisconsin) |
| INVENTOR(S) | Timothy D. Heath (Madison, Wisconsin); Lisa Ann Krugner-Higby (Belleville, Wisconsin); Amy Lautenbach (Cottage Grove, Wisconsin) |
| ABSTRACT | Provided herein is technology relating to incorporation of drugs into liposomes and particularly, but not exclusively, to methods for incorporating drugs into liposomes using a weak base and related compositions. |
| FILED | Thursday, May 06, 2021 |
| APPL NO | 17/313334 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 9/1278 (20130101) Original (OR) Class A61K 31/65 (20130101) A61K 31/485 (20130101) A61K 31/4706 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/773 (20130101) Y10S 977/906 (20130101) Y10S 977/907 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059500 | Yantasee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon); PDX Pharmaceuticals, Inc. (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); PDX Pharmaceuticals, Inc. (Portland, Oregon) |
| INVENTOR(S) | Wassana Yantasee (Lake Oswego, Oregon); Moataz Reda (Portland, Oregon); Worapol Ngamcherdtrakul (Portland, Oregon) |
| ABSTRACT | Disclosed herein are therapeutic constructs including a delivery particle, at least one mitotic kinase inhibitor, and at least one immune checkpoint inhibitor. Also disclosed are therapeutic constructs including a mitotic kinase inhibitor, an immune checkpoint inhibitor, and a chemical linker. These therapeutic constructs cause cancer death by both therapeutic and immune effects and promote targeted delivery of more therapeutics to the surviving cancer cells in a positive feed-back loop. They enhance therapeutic index of free drugs and can be used intratumorally or systemically. This strategy can treat broad cancer types and is particular useful for cancer without obvious receptors for cancer-targeted delivery of otherwise toxic therapeutics. |
| FILED | Wednesday, May 10, 2023 |
| APPL NO | 18/315448 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/143 (20130101) Original (OR) Class A61K 9/146 (20130101) A61K 31/519 (20130101) A61K 45/06 (20130101) A61K 47/6803 (20170801) A61K 47/6849 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/2827 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059582 | Kiani |
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| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Mehdi Kiani (State College, Pennsylvania) |
| ABSTRACT | A method and system of neural stimulation and imaging of nervous system of a subject. The method includes the steps of providing an interface device operable to generate an ultrasonic beam for neuroniodulation and imaging of a targeted neural structure of a subject, implanting the interface device in the subject, and providing and disposing an external coil array over the targeted neural structure of the subject, wherein the external coil array is wirelessly powering and communicating with the interface device. |
| FILED | Friday, October 11, 2019 |
| APPL NO | 17/283983 |
| ART UNIT | 3798 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/42 (20130101) A61B 8/565 (20130101) A61B 8/0808 (20130101) A61B 8/4472 (20130101) A61B 8/4483 (20130101) A61B 8/4488 (20130101) A61B 8/4494 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) A61N 1/37223 (20130101) A61N 1/37235 (20130101) A61N 7/00 (20130101) Original (OR) Class A61N 2007/0026 (20130101) A61N 2007/0047 (20130101) A61N 2007/0052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060318 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Zheng-Rong Lu (Cleveland, Ohio); Da Sun (Cleveland, Ohio); Rebecca Schur (Cleveland, Ohio) |
| ABSTRACT | A nanosized complex includes a nucleic acid and a compound comprising formula (I): wherein R1 is an alkylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted alkyl group, an alkenyl group, an acyl group, or an aromatic group, or a polymer, a targeting group, a detectable moiety, or a linker, or a combination thereof, and at least one of R4 and R5 includes a retinoid or retinoid derivative that targets and/or binds to an interphotoreceptor retinoid binding protein; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof. |
| FILED | Thursday, July 30, 2020 |
| APPL NO | 16/943008 |
| ART UNIT | 1699 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Acyclic or Carbocyclic Compounds C07C 403/10 (20130101) Original (OR) Class C07C 403/12 (20130101) C07C 403/14 (20130101) C07C 403/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060330 | Freundlich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Joel S. Freundlich (New Brunswick, New Jersey); David Alland (New Brunswick, New Jersey); Matthew B. Neiditch (New Brunswick, New Jersey); Pradeep Kumar (New Brunswick, New Jersey); Glenn Capodagli (New Brunswick, New Jersey); Divya Awasthi (New Brunswick, New Jersey); Sean Ekins (New Brunswick, New Jersey) |
| ABSTRACT | The invention provides compounds of formula I: and salts thereof wherein R1-R5 have any of the meanings described in the specification. The compounds are useful for treating bacterial infections (e.g. tuberculosis). |
| FILED | Tuesday, November 02, 2021 |
| APPL NO | 17/517569 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4409 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) Heterocyclic Compounds C07D 231/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060332 | Betts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| INVENTOR(S) | Brian Betts (Tampa, Florida); Said M. Sebti (Tampa, Florida); Harshani Lawrence (Tampa, Florida); Nicholas Lawrence (Tampa, Florida); Claudio Anasetti (Tampa, Florida); Joseph Pidala (Tampa, Florida) |
| ABSTRACT | Disclosed herein are compounds and methods for reducing the risk of developing, preventing, or treating graft versus host disease (GVHD) in a subject. The compounds can concurrently block Aurora kinase A and JAK2 signal transduction which synergistically suppresses alloreactive human T-cells in vitro, prevents xenogeneic graft-versus-host disease without impairing anti-tumor responses, and promotes the development and suppressive potency of CD39+ inducible Treg. In certain aspects, disclosed are compounds of Formula I-V. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/098990 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/506 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 239/48 (20130101) Original (OR) Class C07D 401/12 (20130101) C07D 403/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060334 | Huigens, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Robert William Huigens, III (Williston, Florida); Hongfen Yang (Gainesville, Florida) |
| ABSTRACT | The present invention provides phenazine derivatives, such as compounds of Formula (I). The compounds of the invention are expected to be antimicrobial agents and may act by a microbial warfare strategy (e.g., a reactive oxygen species (ROS)-based competition strategy). The present invention also provides compositions, kits, uses, and methods that involve the compounds of the invention, which may be useful in preventing or treating a microbial infection (e.g., a bacterial infection or mycobacterial infection) in a subject, inhibiting the growth and/or reproduction of a microorganism (e.g., a bacterium or mycobacterium), killing a microorganism (e.g., a bacterium or mycobacterium), inhibiting the formation and/or growth of a biofilm, reducing or clearing a biofilm, and/or disinfecting a surface. |
| FILED | Friday, March 11, 2022 |
| APPL NO | 17/692536 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 241/46 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060337 | Tepe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Jetze J. Tepe (East Lansing, Michigan); Theresa A. Lansdell (East Lansing, Michigan); Evert Njomen (Ypsilanti, Michigan); Corey Lee Jones (Madison, Wisconsin) |
| ABSTRACT | The disclosure is directed to substituted dibenzo[b,f]azepines of the formula (II): wherein the variables n, X3, R1, R2, R4, and R5 are defined herein, and uses of such compounds to treat conditions including neurodegenerative diseases and cancers. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/671480 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 279/22 (20130101) Original (OR) Class C07D 417/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060350 | David et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Sunil A. David (Minneapolis, Minnesota); Yupeng Li (Minneapolis, Minnesota); Michael Brush (Minneapolis, Minnesota); Kathryn Trautman (Minneapolis, Minnesota); Collin Gustafson (Minneapolis, Minnesota); Daniel Maurer (Minneapolis, Minnesota); Balaji Pathakumari (Minneapolis, Minnesota) |
| ABSTRACT | The invention provides a compound of formula (I) or a salt thereof, wherein R1, R2, R3 and R4 have any of the values described in the specification, as well as compositions comprising a compound of formula (I). The compounds are useful as immunostimulatory agents. |
| FILED | Friday, June 28, 2019 |
| APPL NO | 17/256933 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 47/61 (20170801) A61K 47/545 (20170801) A61K 47/6923 (20170801) A61K 2039/55511 (20130101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6561 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060358 | Ibrahim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Mississippi (University, Mississippi) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohamed Ali Mohamed Ali Ibrahim (Oxford, Mississippi); Jason Richard Paris (Little Rock, Arkansas); Larry Anthony Walker (Milan, Tennessee); Abbas Gholipour Shilabin (Johnson City, Tennessee); Meirambek Ospanov (Oxford, Mississippi) |
| ABSTRACT | The disclosure relates to compounds of Formula I, methods of making same, pharmaceutical compositions including same, and methods of treating pain and neurological disorders using same: wherein R1 is hydrogen, halogen, hydroxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, aryl, nitro, or cyano; wherein R2 and R3 are independently hydrogen, halogen, aryl, or substituted or unsubstituted alkyl, or wherein R2 and R3 are connected to form an alkyl chain; wherein R4 is a substituted or unsubstituted aryl or heteroaryl group having from 5 to 10 members; wherein X is O, S, N, NH, CH, CH2, or CO; wherein n is from 0 to 10; and wherein the bond indicated by * is a double bond or a single bond based on a valence of X. The compounds selectively bind to CB2, can penetrate the blood brain barrier, and have a half-life of 20 hours or greater. |
| FILED | Tuesday, March 28, 2023 |
| APPL NO | 18/191247 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/04 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060366 | Gray et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Eric Fischer (Chestnut Hill, Massachusetts); Alyssa Verano (Allston, Massachusetts); Zhixiang He (Brookline, Massachusetts); Guangyan Du (Jamaica Plain, Massachusetts); Katherine Donovan (Boston, Massachusetts); Radoslaw Nowak (Boston, Massachusetts); Jing Ting Christine Yuan (Brookline, Massachusetts) |
| ABSTRACT | Disclosed are degraders, pharmaceutical compositions containing them, and methods of making and using the degraders to treat diseases and disorders characterized by aberrant protein activity that can be targeted by cereblon. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 17/255772 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/55 (20170801) A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 495/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060388 | DiMaio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Daniel DiMaio (North Haven, Connecticut); Pengwei Zhang (New Haven, Connecticut); Gabriel Monteiro Da Silva (Ribeirao Preto, Brazil); Weiya Bai (Shanghai, China PRC) |
| ABSTRACT | In various aspects and embodiments the invention provides compositions and methods for facilitating cell penetration of a cargo molecule. In another aspect, the invention provides a method of preventing viral infection in a subject in need thereof, the method comprising providing to the subject a therapeutically effective amount of a polypeptide comprising a cell-penetrating peptide and a retromer binding site. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 17/057501 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/20022 (20130101) C12N 2710/20033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060393 | Kalyanasundaram |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Ramaswamy Kalyanasundaram (Rockford, Illinois) |
| ABSTRACT | The present invention is a multivalent vaccine for immunizing an animal against filariasis. In some embodiments, the antigens of the multivalent vaccine are protein-based, DNA-based, or a combination thereof. This invention also provides a method and kit for detecting a filarial nematode and determining vaccine efficacy. |
| FILED | Wednesday, August 29, 2018 |
| APPL NO | 16/116203 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0003 (20130101) A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/545 (20130101) A61K 2039/55505 (20130101) Peptides C07K 14/4354 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0065 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) G01N 2333/4353 (20130101) G01N 2469/10 (20130101) G01N 2469/20 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060394 | Sentman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Charles L. Sentman (Grantham, New Hampshire); Albert Gacerez (Lebanon, New Hampshire) |
| ABSTRACT | Nucleic acid constructs, vectors, and recombinant cells harboring the nucleic acid constructs or vectors are disclosed. The nucleic acid constructs include genes encoding a chimeric antigen receptor (CAR) and/or one or more transcription factors, optionally mutated. The transcription factors include those that mediate proinflammatory cytokine expression, e.g., T-bet, STAT1, or STAT4. Methods are disclosed of co-expression of the CAR and the transcription factor in a human or non-human immune cell, preferably human T cells. Also disclosed are methods for using these cells for immunotherapy, e.g., in treating cancer, infection, autoimmunity, allergy or inflammation diseases by the administration of a prophylactically or therapeutically effective amount of one or more of the nucleic acid constructs, vectors, and/or immune cells, e.g., human CAR-T cells, described herein. |
| FILED | Friday, April 28, 2017 |
| APPL NO | 16/096562 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4702 (20130101) Original (OR) Class C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 16/2827 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2740/10043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060395 | Ildefonso et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Cristhian J. Ildefonso (Gainesville, Florida); Alfred S. Lewin (Gainesville, Florida); Qiuhong Li (Gainesville, Florida) |
| ABSTRACT | The present invention provides methods and compositions for treating and/or preventing age related macular degeneration and other conditions involving macular degeneration, ocular neovascularization, or inflammation, including ocular inflammation. In some embodiments, the methods comprise administering an expression vector that delivers a secretable and cell penetrating Nrf2 to a subject in need thereof. |
| FILED | Tuesday, June 08, 2021 |
| APPL NO | 17/342120 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/1709 (20130101) A61K 48/0075 (20130101) Peptides C07K 14/4702 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/02 (20130101) C07K 2319/10 (20130101) C07K 2319/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060396 | Pozzi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee); The United States as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee); The United States as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Ambra A. Pozzi (Nashville, Tennessee); Manuel Chiusa (Nashville, Tennessee); Jack J. Hawiger (Nashville, Tennessee); Jozef Zienkiewicz (Nashville, Tennessee) |
| ABSTRACT | Disclosed herein are compositions and methods for inhibiting collagen production mediated by the Fused in Sarcoma (FUS) ribonucleoprotein. As disclosed herein, the C terminal domain of FUS contains an uncommon nuclear localization sequence (NLS) motif called PY-NLS that binds the nuclear import receptor transportin. Phosphorylation of FUS leads to its association with transportin and nuclear translocation with consequent increased in collagen production. Therefore, disclosed herein is an isolated peptide having a transportin-binding moiety, which inhibits FUS from binding transportin, linked to a membrane translocating motif. These compositions and methods can be used to inhibit FUS-mediated collagen production, and treat fibrotic disease involving FUS-mediated collagen accumulation in kidneys and other organs displaying fibrotic diseases. |
| FILED | Monday, January 29, 2018 |
| APPL NO | 16/481128 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 38/1777 (20130101) A61K 38/1825 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) Peptides C07K 14/50 (20130101) C07K 14/4703 (20130101) Original (OR) Class C07K 14/70557 (20130101) C07K 2319/02 (20130101) C07K 2319/10 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060397 | Cohen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tufts Medical Center (Boston, Massachusetts); Trustees of Tufts College (Medford, Massachusetts); On Target Therapeutics LLC (Wellesley, Massachusetts) |
| ASSIGNEE(S) | Tufts Medical Center (Boston, Massachusetts); Trustees of Tufts College (Medford, Massachusetts); On Target Therapeutics LLC (Wellesley, Massachusetts) |
| INVENTOR(S) | Charles Cohen (Weston, Massachusetts); Krishna Kumar (Cambridge, Massachusetts); Jamie Raudensky Doyle (Newton, Massachusetts); Alan S. Kopin (Wellesley, Massachusetts) |
| ABSTRACT | The present application provides methods for preparing soluble lipidated ligand agents comprising a ligand entity and a lipid entity, and in some embodiments, provides relevant parameters of each of these components, thereby enabling appropriate selection of components to assemble active agents for any given target of interest. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/525169 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/543 (20170801) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/4703 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/5023 (20130101) G01N 2405/00 (20130101) G01N 2440/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060411 | Nussenzweig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Michel Nussenzweig (New York, New York); Zijun Wang (New York, New York) |
| ABSTRACT | This disclosure provides novel neutralizing anti-SARS-CoV-2 antibodies or antigen-binding fragments thereof. The disclosed anti-SARS-CoV-2 antibodies constitute a novel therapeutic strategy in protection from SARS-CoV-2 infections. |
| FILED | Thursday, January 13, 2022 |
| APPL NO | 17/575246 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/35 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) G01N 2800/26 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060412 | Regev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College, MA (Cambridge, Massachusetts) |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Feng Zhang (Cambridge, Massachusetts); Naomi Habib (Cambridge, Massachusetts); Yinqing Li (Cambridge, Massachusetts); Matthias Heidenreich (Cambridge, Massachusetts); Lukasz Swiech (Cambridge, Massachusetts); Anindita Basu (Cambridge, Massachusetts); David Weitz (Cambridge, Massachusetts); Inbal Avraham Davidi (Cambridge, Massachusetts) |
| ABSTRACT | Transcriptomes of individual neurons provide rich information about cell types and dynamic states. However, it is difficult to capture rare dynamic processes, such as adult neurogenesis, because isolation from dense adult tissue is challenging, and markers for each phase are limited. Here, Applicants developed Nuc-seq, Div-Seq, and Dronc-Seq. Div-seq combines Nuc-Seq, a scalable single nucleus RNA-Seq method, with EdU-mediated labeling of proliferating cells. Nuc-Seq can sensitively identify closely related cell types within the adult hippocampus. Div-Seq can track transcriptional dynamics of newborn neurons in an adult neurogenic region in the hippocampus. Dronc-Seq uses a microfluidic device to co-encapsulate individual nuclei in reverse emulsion aqueous droplets in an oil medium together with one uniquely barcoded mRNA-capture bead. Finally, Applicants found rare adult newborn GABAergic neurons in the spinal cord, a non-canonical neurogenic region. Taken together, Nuc-Seq, Div-Seq and Dronc-Seq allow for unbiased analysis of any complex tissue. |
| FILED | Thursday, October 27, 2016 |
| APPL NO | 16/087036 |
| ART UNIT | 1675 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1036 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1093 (20130101) C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2537/165 (20130101) C12Q 2537/165 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) C12Q 2565/514 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060415 | Pasqualini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Renata Pasqualini (New Brunswick, New Jersey); Wadih Arap (New Brunswick, New Jersey); Fernanda Iamassaki Staquicini (New Brunswick, New Jersey); Fortunato Ferrara (Santa Fe, New Mexico); Sara D'Angelo (Santa Fe, New Mexico); Andrew R. M. Bradbury (Santa Fe, New Mexico) |
| ABSTRACT | Isolated or recombinant EphA5 or GRP78 targeting antibodies are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer. A method of rapidly identifying antibodies or antibody fragments for the treatment of cancer using a combination of in vitro and in vivo methodologies is also provided. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/592828 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/07 (20130101) A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 47/6803 (20170801) A61K 47/6817 (20170801) A61K 47/6843 (20170801) A61K 47/6849 (20170801) A61K 47/6891 (20170801) A61K 49/0008 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/47 (20130101) C07K 16/005 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/2866 (20130101) C07K 16/3023 (20130101) C07K 2317/21 (20130101) C07K 2317/35 (20130101) C07K 2317/55 (20130101) C07K 2317/73 (20130101) C07K 2317/77 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/64 (20130101) C12N 15/1037 (20130101) C12N 2810/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5011 (20130101) G01N 33/57423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060555 | Ahangari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut); University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut); UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Farida Ahangari (New Haven, Connecticut); Naftali Kaminski (New Haven, Connecticut); Carlos Fernandez-Hernando (New Haven, Connecticut); Raman Bahal (Glastonbury, Connecticut) |
| ABSTRACT | In one aspect, the present disclosure provides a microRNA-33 (miR-33) inhibitor comprising a peptide nucleic acid covalently bound to a pH low insertion peptide. In another aspect, the present disclosure provides a method of treating pulmonary fibrosis in a subject, the method comprising administering to the subject a therapeutically effective amount of the miR-33 inhibitor. In some embodiments, the pulmonary fibrosis is idiopathic pulmonary fibrosis. |
| FILED | Friday, May 13, 2022 |
| APPL NO | 17/663378 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) Original (OR) Class C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060576 | Thon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Stellular Bio, Inc. (Watertown, Massachusetts) |
| ASSIGNEE(S) | Stellular Bio, Inc. (Watertown, Massachusetts) |
| INVENTOR(S) | Jonathan Thon (Watertown, Massachusetts); Brad Dykstra (Watertown, Massachusetts) |
| ABSTRACT | Methods for producing megakaryocytic progenitors (preMKs) and megakaryocytes (MKs) from stem cells are provided. The present disclosure further provides compositions comprising preMKs and MKs and their lysates, and also methods of use of preMKs, MKs, their lysates and compositions thereof. |
| FILED | Saturday, January 05, 2019 |
| APPL NO | 16/957918 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0075 (20130101) C12N 5/0644 (20130101) Original (OR) Class C12N 2501/91 (20130101) C12N 2501/115 (20130101) C12N 2501/125 (20130101) C12N 2501/145 (20130101) C12N 2501/155 (20130101) C12N 2501/165 (20130101) C12N 2501/415 (20130101) C12N 2501/2303 (20130101) C12N 2501/2306 (20130101) C12N 2501/2309 (20130101) C12N 2506/45 (20130101) C12N 2513/00 (20130101) C12N 2533/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060579 | Murry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Charles E. Murry (Seattle, Washington); Lil Pabon (Seattle, Washington); Nathan Palpant (Seattle, Washington) |
| ABSTRACT | Provided herein are methods that enable the polarization of hPSC mesoderm such that closely related yet distinct cardiovascular populations can be generated efficiently without the need of post-facto enrichment. |
| FILED | Wednesday, February 26, 2020 |
| APPL NO | 16/801559 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/545 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) Original (OR) Class C12N 2501/16 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2501/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060588 | Jaenisch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| INVENTOR(S) | Rudolf Jaenisch (Brookline, Massachusetts); X. Shawn Liu (Cambridge, Massachusetts); Hao Wu (Newton, Massachusetts) |
| ABSTRACT | The invention relates to methods of modifying DNA methylation by contacting a cell with a catalytically inactive site specific nuclease fused to an effector domain having methylation or demethylation activity and one or more guide sequences. |
| FILED | Wednesday, July 06, 2022 |
| APPL NO | 17/858758 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) A61K 35/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/1007 (20130101) C12N 15/11 (20130101) C12N 15/86 (20130101) C12N 15/907 (20130101) C12N 2310/20 (20170501) C12N 2740/15031 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 201/01037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060611 | Salomon et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Daniel Salomon (San Diego, California); John Friedewald (Chicago, Illinois); Sunil Kurian (San Diego, California); Michael M. Abecassis (Highland Park, Illinois); Steve Head (Lakeside, California); Phillip Ordoukhanian (San Diego, California) |
| ABSTRACT | By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR. |
| FILED | Thursday, September 12, 2019 |
| APPL NO | 16/569119 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2537/165 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 25/10 (20190201) G16B 40/20 (20190201) G16B 40/30 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060615 | Nelson et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | William G. Nelson (Towson, Maryland); Srinivasan Yegnasubramanian (Baltimore, Maryland); Xiaohui Lin (Redlands, California); Traci J. Speed (Baltimore, Maryland); Zachery Reichert (Baltimore, Maryland) |
| ABSTRACT | The present invention provides methods for discovering agents that are effective in reversing epigenetic silencing by inhibiting the interaction of methyl-binding (MBD) proteins with methylated genomic DNA. Also provided are methods for reactivating silenced genes having CpG island hypermethylation along with methods for treatment and prevention of diseases, such as cancer and sickle cell anemia, by administering an agent that modulates methyl-binding domain (MBD) protein-mediated transcriptional repression, thereby increasing gene transcription to prevent or treat disease. Additionally, compounds identified by the present invention useful for treatment and prevention of diseases, such as cancer and sickle cell anemia, are provided. |
| FILED | Monday, February 25, 2019 |
| APPL NO | 16/285019 |
| ART UNIT | 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/136 (20130101) A61K 31/381 (20130101) A61K 31/404 (20130101) A61K 31/433 (20130101) A61K 31/444 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/4184 (20130101) A61K 31/4188 (20130101) A61K 31/4245 (20130101) A61K 31/4439 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/136 (20130101) C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/6875 (20130101) G01N 2500/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060618 | Barlogie et al. |
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| FUNDED BY |
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| APPLICANT(S) | BioVentures, LLC (Little Rock, Arkansas) |
| ASSIGNEE(S) | BioVentures LLC (Little Rock, Arkansas) |
| INVENTOR(S) | Bart Barlogie (Little Rock, Arkansas); Pingping Qu (Little Rock, Arkansas); Christoph Heuck (Little Rock, Arkansas); Joshua Epstein (Little Rock, Arkansas) |
| ABSTRACT | The invention provides, inter alia, methods of prognosing a subject with, or suspected of having, multiple myeloma. In certain embodiments, the methods entail testing the gene expression levels of enolase 1 (ENO1), fatty acid binding protein 5 (FABP5), thyroid hormone receptor interactor 13 (TRIP13), transgelin 2 (TAGLN2), and replication factor C (activator 1) 4 (RFC4) in a biological sample isolated from the subject. The invention also provides methods of treatment for multiple myeloma, as well as kits, oligonucleotides, and systems for performing the methods provided by the invention. |
| FILED | Monday, August 24, 2020 |
| APPL NO | 17/001173 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 25/10 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061143 | Dickson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Robert Martin Dickson (Atlanta, Georgia); Tzu-Hsueh Huang (Atlanta, Georgia) |
| ABSTRACT | The invention is directed to a method for rapidly determining antibiotic susceptibility in bodily fluid samples based on rigorous multidimensional statistical metrics. In some embodiments, the method incorporates flow cytometry to determine susceptibility. In preferred embodiments, the method is adapted for use with samples with low bacterial counts. |
| FILED | Friday, January 12, 2018 |
| APPL NO | 16/477260 |
| ART UNIT | 1759 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1459 (20130101) Original (OR) Class G01N 21/39 (20130101) G01N 2015/1006 (20130101) G01N 2015/1402 (20130101) G01N 2015/1488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061186 | Spranger et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Stefani Spranger (Boston, Massachusetts); Ellen Duong (Quincy, Massachusetts) |
| ABSTRACT | Provided herein are compositions and methods of use relating to a novel class of dendritic cells, referred to herein as ISG+ DC, having anti-tumor activity. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 17/348704 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/14 (20130101) G01N 33/5047 (20130101) Original (OR) Class G01N 33/6893 (20130101) G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061187 | Birnbaum et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael Birnbaum (Cambridge, Massachusetts); Connor Dobson (Somerville, Massachusetts) |
| ABSTRACT | Compositions of retroviruses and methods of using the same for gene delivery, wherein the retroviruses comprise a viral envelope protein comprising at least one mutation that diminishes its native function, a non-viral membrane-bound protein comprising a membrane-bound domain and an extracellular targeting domain. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 16/826665 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 14/4748 (20130101) C07K 14/5437 (20130101) C07K 14/70532 (20130101) C07K 14/70539 (20130101) C07K 16/2803 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/035 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2740/15045 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061188 | Birnbaum et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael Birnbaum (Arlington, Massachusetts); Connor Dobson (Somerville, Massachusetts) |
| ABSTRACT | Compositions of retroviruses and methods of using the same for gene delivery, wherein the retroviruses comprise a viral envelope protein comprising at least one mutation that diminishes its native function, a non-viral membrane-bound protein comprising a membrane-bound domain and an extracellular targeting domain. |
| FILED | Wednesday, August 30, 2023 |
| APPL NO | 18/458628 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 14/4748 (20130101) C07K 14/5437 (20130101) C07K 14/70532 (20130101) C07K 14/70539 (20130101) C07K 16/2803 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/035 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2740/15045 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061194 | Swager et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy Manning Swager (Newton, Massachusetts); Hadley Sikes Johnson (Arlington, Massachusetts); Qifan Zhang (Revere, Massachusetts); Eric Alexander Miller (Somerville, Massachusetts); Lukas Zeininger (Berlin, Germany); Ki-Joo Sung (Minneapolis, Minnesota); Kosuke Yoshinaga (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments described herein may be useful in the detection of analytes. The systems and methods may allow for a relatively simple and rapid way for detecting analytes such as chemical and/or biological analytes and may be useful in numerous applications including sensing, food manufacturing, medical diagnostics, performance materials, dynamic lenses, water monitoring, environmental monitoring, detection of proteins, detection of DNA, among other applications. For example, the systems and methods described herein may be used for determining the presence of a contaminant such as bacteria (e.g., detecting pathogenic bacteria in food and water samples which helps to prevent widespread infection, illness, and even death). Advantageously, the systems and methods described herein may not have the drawbacks in current detection technologies including, for example, relatively high costs, long enrichment steps and analysis times, and/or the need for extensive user training. Another advantageous feature provided by the systems and methods described herein includes fabrication in a relatively large scale. In some embodiments, the systems and methods may be used in conjunction with a detector including handheld detectors incorporated with, for example, smartphones (e.g., for the on-site detection of analytes such as pathogenic bacteria). |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 17/545979 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) C12Q 1/701 (20130101) C12Q 1/6834 (20130101) C12Q 2563/159 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/59 (20130101) G01N 21/77 (20130101) G01N 21/78 (20130101) G01N 33/5432 (20130101) Original (OR) Class G01N 33/54366 (20130101) G01N 33/56983 (20130101) G01N 2021/7783 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061201 | Pilch et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Daniel S. Pilch (New Brunswick, New Jersey); Edgar Ferrer-González (New Brunswick, New Jersey); Edmond J. LaVoie (New Brunswick, New Jersey) |
| ABSTRACT | The invention provides a compound of formula I: or a salt thereof, wherein Y, Z, L, and W have any of the values described in the specification, as well as compositions comprising a compound of formula I or a salt thereof. The compounds are useful as tools for visualizing FtsZ and monitoring cell division in a broad range of Gram-positive and Gram-negative bacterial pathogens of acute clinical importance and for identifying new FtsZ inhibitors. |
| FILED | Monday, September 21, 2020 |
| APPL NO | 17/027513 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/52 (20130101) G01N 33/582 (20130101) Original (OR) Class G01N 33/56911 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061204 | Coon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Joshua Coon (Middleton, Wisconsin); Harald Marx (Madison, Wisconsin) |
| ABSTRACT | In shotgun proteomics, generally only a fraction of peptides from a parent protein are actually detected. Because a large portion of the protein sequence is not detected, it is often impossible to determine whether the expressed protein is present in a modified, spliced, or truncated form. Provided herein are methods and systems for analyzing polypeptides which allow for the increase of the mean sequence coverage of a protein concomitant with bioinformatics analysis in order to distinguish putative proteoforms with improved amino acid resolution. Aspects of the invention include (1) a deep sequencing strategy to provide more protein sequence coverage than is typically achieved, and (2) a computational approach to view protein expression across its full length and identify regions of the protein that are potentially subject to such regulation. This technology has global utility in proteomics and will be of particular use for the analysis of biosimilar protein drug therapeutics. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/231977 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6824 (20130101) G01N 33/6842 (20130101) G01N 33/6848 (20130101) Original (OR) Class G01N 2570/00 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) G16B 30/20 (20190201) G16B 40/00 (20190201) G16B 40/10 (20190201) G16B 40/30 (20190201) Electric Discharge Tubes or Discharge Lamps H01J 49/004 (20130101) H01J 49/0036 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061248 | Juchem et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Christoph Juchem (Ridgefield, Connecticut); Michael Sebastian Theilenberg (New York, New York); Yun Shang (New York, New York); Jalal Ghazouani (Hamburg, Germany) |
| ABSTRACT | An apparatus for fabricating non-planar coils includes a rotating table driven by a first motor; a wire approach height adjustment arm driven by a second motor; and a synchronization module configured such that a wire traversing from the height adjustment arm to a bobbin on the rotating table passes into a non-planar groove cut in the bobbin without damaging the wire. Performing magnetic resonance (MR) measurements includes a plurality of coil units configured for generating a gradient or shim magnetic field. The coil unit includes a plurality of coil windings, and each coil winding is separated longitudinally from an adjacent coil winding. A single pair of electrically conducting leads is configured to cause current to flow through all of the plurality of coil windings in the coil unit. Techniques include methods to fabricate and operate the apparatus. |
| FILED | Monday, January 31, 2022 |
| APPL NO | 17/649462 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/3856 (20130101) G01R 33/3858 (20130101) Original (OR) Class G01R 33/3875 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061328 | Valdes et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Pablo A. Valdes (Hanover, New Hampshire); David W. Roberts (Lyme, New Hampshire); Keith D. Paulsen (Hanover, New Hampshire); Frederic Leblond (Montreal, Canada) |
| ABSTRACT | An imaging system includes an illumination device for illuminating a target. A surgical microscope receives light from the target, the surgical microscope comprising at least one optical output port at which at least a portion of the received light is provided as an output from the surgical microscope. A tunable filter receives the portion of the received light provided as the output from the surgical microscope, the tunable filter being tunable to pass a filtered portion of the received light, the filtered portion of the received light having a plurality of wavelengths selected by the tunable filter and provided as output from the tunable filter. A high-resolution, broad-bandwidth electronic camera receives the light of a plurality of wavelengths selected by the tunable filter, the electronic camera converting the light of a plurality of wavelengths selected by the tunable filter to a plurality of electrical signals. A processor processes the plurality of electrical signals to form an image of the target. |
| FILED | Monday, May 08, 2023 |
| APPL NO | 18/144767 |
| ART UNIT | 3798 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/063 (20130101) Optical Elements, Systems, or Apparatus G02B 21/06 (20130101) Original (OR) Class G02B 21/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062178 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | David L. Wilson (Cleveland Heights, Ohio); Naomi Joseph (Cleveland, Ohio); Jonathan H. Lass (Cleveland, Ohio); Beth Ann Benetz (Cleveland, Ohio); Harry J. Menegay (Cleveland, Ohio); Elizabeth Fitzpatrick (Nashville, Tennessee) |
| ABSTRACT | Embodiments discussed herein facilitate automated and/or semi-automated segmentation of endothelial cells via a trained deep learning model. One example embodiment is a method, comprising: accessing an optical microscopy image comprising a set of corneal endothelial cells of a patient of a keratoplasty; pre-processing the optical microscopy image to generate a pre-processed optical microscopy image via correcting for at least one of shading or illumination artifacts in the optical microscopy image; segmenting, based at least in part on a trained deep learning (DL) model, a plurality of corneal endothelial cells of the set of corneal endothelial cells in the pre-processed optical microscopy image; and displaying, via a graphical user interface (GUI), at least the segmented plurality of corneal endothelial cells. |
| FILED | Tuesday, January 05, 2021 |
| APPL NO | 17/141564 |
| ART UNIT | 2671 — Optics |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) Optical Elements, Systems, or Apparatus G02B 21/367 (20130101) Image Data Processing or Generation, in General G06T 7/10 (20170101) G06T 7/11 (20170101) Original (OR) Class G06T 2207/30024 (20130101) Image or Video Recognition or Understanding G06V 10/44 (20220101) G06V 10/82 (20220101) G06V 10/764 (20220101) G06V 20/695 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062298 | Yates et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Retivue, LLC (Charlottesville, Virginia) |
| ASSIGNEE(S) | RetiVue, LLC (Charlottesville, Virginia) |
| INVENTOR(S) | Paul A. Yates (Charlottesville, Virginia); Ming Lai (Pleasanton, California); Ta-Wei Yi (Pleasanton, California) |
| ABSTRACT | The present invention contemplates an infant eye model for wide field retinal imaging by implementing nominal physical parameters and optical characteristics found in scientific literature and by simulating retinal features and details found in real eye images. The present invention also contemplates implementing a corneal model with a translucent plastic to mimic image haze and 1st Purkinje reflection. The present invention also contemplates implementing a birefringent layer to the lens posterior surface to simulate 4th Purkinje reflection and its brightness variation. The present invention further contemplates implementing a photo-realistic retinal hemisphere shell to provide retinal details and demonstrate retinopathy associated with retinal diseases. |
| FILED | Wednesday, August 16, 2017 |
| APPL NO | 16/325781 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/14 (20130101) A61B 3/1173 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 23/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062422 | Min et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Wei Min (Fort Lee, New Jersey); Lingyan Shi (Brooklyn, New York) |
| ABSTRACT | Incorporation of deuterium into the lipids, proteins, and/or genetic material in cells, tissues, organs, or organisms, including animals, such as humans, and plants, by administration of heavy water, allows for the spectral determination of levels of lipids, proteins, and/or genetic material using Raman spectroscopy, such as stimulated Raman spectroscopy. Following administration of a drug, changes in the relative amounts of lipid, protein, and/or genetic materials can be determined, and the efficacy, or lack thereof, of the administered drug can be determined. |
| FILED | Wednesday, January 27, 2021 |
| APPL NO | 17/159591 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0002 (20130101) A61K 49/0004 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 33/6848 (20130101) G01N 2021/656 (20130101) G01N 2458/15 (20130101) G01N 2500/10 (20130101) G01N 2570/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/10 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062436 | Ning et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio); The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corp. (Bloomington, Indiana); Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Xia Ning (Columbus, Ohio); Zhiyun Ren (Sunnyvale, California); Bo Peng (Columbus, Ohio); Titus K. Schleyer (Indianapolis, Indiana) |
| ABSTRACT | Disclosed embodiments include computer-implemented methods and systems that can efficiently generate highly relevant recommended search terms to clinicians. A hybrid collaborative filtering model recommends search terms for a specific patient to the clinician. The model draws on information from patients' clinical encounters and the searches that were performed during the clinical encounters. To generate recommendations, the model uses search terms which are (1) frequently co-occurring with the ICD codes recorded for the patient and (2) highly relevant to the most recent search terms. One variation of the model uses only the most recent ICD codes assigned to the patient. Another variation uses all ICD codes. Comprehensive experiments of embodiments of the methods and systems have demonstrate high levels of performance. |
| FILED | Monday, November 15, 2021 |
| APPL NO | 17/526591 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Electric Digital Data Processing G06F 16/24578 (20190101) G06F 17/16 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/20 (20180101) Original (OR) Class G16H 70/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062444 | Conzen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Suzanne Conzen (Chicago, Illinois); Lei Huang (Chicago, Illinois); Maria Kocherginsky (Chicago, Illinois); Diana Szymanski (Chicago, Illinois) |
| ABSTRACT | Embodiments are directed to kits and methods of treating a breast cancer patient with a glucocorticoid receptor antagonist with or without an anticancer agent or compound after the patient has been determined to be susceptible to treatment with the glucocorticoid receptor antagonist. |
| FILED | Wednesday, December 12, 2018 |
| APPL NO | 16/217350 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6827 (20130101) C12Q 1/6837 (20130101) C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) Original (OR) Class G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062926 | Babakhani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Hamed Rahmani (Belle Mead, New Jersey); Hidemasa Mitsui (Santa Clara, California) |
| ABSTRACT | Systems and methods for utilizing a small form-factor, wirelessly powered transceiver are disclosed. In one embodiment, a wireless powered transceiver includes a receive antenna configured to receive a receive signal, a transmit antenna configured to transmit a transmit signal, a power harvesting system including a rectifier circuit configured convert radio frequency energy from the receive signal into DC (direct current) voltage, and a power management unit (PMU) configured to set the operating mode and biasing condition of the receive and transmit circuitry blocks and provide DC voltage from the receive circuitry block to the transmit circuitry block to maintain a minimum voltage, a receiver circuitry block configured to provide energy from the receive signal to the power harvesting system, and a transmitter circuitry block including a data modulator circuit, the data modulator circuit configured to generate the transmit signal using DC voltage received from the power management unit. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/929959 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/001 (20200101) H02J 50/27 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE50075 | Damiano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Edward R. Damiano (Acton, Massachusetts); Firas H. El-Khatib (Allston, Massachusetts) |
| ABSTRACT | Apparatus and methods calculate and deliver doses of insulin and optionally glucagon into a subject. Online operation controls delivery of correction doses of insulin automatically in response to regular glucose measurements from a sensor, and offline operation calculates and delivers correction doses based on isolated glucose measurements and information gathered autonomously during preceding online operation. In another aspect, offline operation includes automatically calculating and administering meal doses based on information gathered autonomously during preceding periods of online operation. Both methods include generating relevant control parameters tailored to the individual and continually converged upon and potentially modulated during online operation. The control parameters are employed in real time during periods of offline operation to regulate glucose level without the need for user-provided control parameters such as correction factors and insulin-to-carbohydrate ratios. |
| FILED | Thursday, May 06, 2021 |
| APPL NO | 17/313401 |
| ART UNIT | 3992 — Central Reexamination Unit (Electrical) |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4839 (20130101) A61B 5/14532 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 5/16827 (20130101) A61M 2005/14208 (20130101) A61M 2005/14296 (20130101) A61M 2202/07 (20130101) A61M 2202/0486 (20130101) A61M 2205/50 (20130101) A61M 2205/502 (20130101) A61M 2205/3584 (20130101) A61M 2230/005 (20130101) A61M 2230/201 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 15/00 (20180101) G16H 20/17 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12058996 | Toner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mehmet Toner (Charlestown, Massachusetts); Mustafa Korkut Uygun (Newton, Massachusetts); Shannon N. Tessier (Framingham, Massachusetts); Shannon L. Stott (Stoneham, Massachusetts); Lindong Weng (Arlington, Massachusetts); Reinier Johan De Vries (Boston, Massachusetts); Casie A. Pendexter (Rockland, Massachusetts); Stephanie E J Cronin (Boston, Massachusetts) |
| ABSTRACT | This disclosure is related to methods of preserving biological samples, organs, and organisms. This disclosure is based, at least in part, on the discovery that in the presence of heterogenous extracellular ice, endothelial cells have improved attachment and viability after preservation, and particularly by uniformly nucleating ice across the microvasculature using ice nucleating agents, the chance of intracelluar ice formation can be significantly reduced. |
| FILED | Thursday, June 14, 2018 |
| APPL NO | 16/622457 |
| ART UNIT | 1638 — SELECT * FROM codes_techcenter; |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Original (OR) Class A01N 1/0294 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059480 | Ganesh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Karuna Ganesh (New York, New York); Manuel Valiente (Madrid, Spain); Joan Massague (New York, New York) |
| ABSTRACT | The present invention relates to methods and compositions for inhibiting metastatic spread of cancer and/or inhibiting progression of pre-existing metastatic disease in a subject using L1CAM inhibition. |
| FILED | Monday, October 10, 2022 |
| APPL NO | 18/045357 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/519 (20130101) A61K 45/06 (20130101) A61K 48/0016 (20130101) A61K 48/0066 (20130101) Original (OR) Class A61K 48/0083 (20130101) A61K 48/0091 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059767 | Paine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| INVENTOR(S) | Tyler Paine (Edmonds, Washington); Christopher Walther (Gig Harbor, Washington); Nicholas Johnson (Bremerton, Washington); Scott Larson (Bremerton, Washington) |
| ABSTRACT | A mechanical assembly to precisely position large objects and align them to be joined with other objects with precision. The assembly does not require power to operate and can therefore be used in a variety of remote and harsh locations. |
| FILED | Friday, January 26, 2024 |
| APPL NO | 18/424705 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Working or Processing of Sheet Metal or Metal Tubes, Rods or Profiles Without Essentially Removing Material; Punching Metal B21D 39/00 (20130101) Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 19/12 (20130101) Details, Components, or Accessories for Machine Tools, e.g Arrangements for Copying or Controlling; Machine Tools in General Characterised by the Construction of Particular Details or Components; Combinations or Associations of Metal-working Machines, Not Directed to a Particular Result B23Q 3/186 (20130101) Original (OR) Class Tools or Bench Devices Not Otherwise Provided For, for Fastening, Connecting, Disengaging or Holding B25B 11/02 (20130101) Motor Vehicles; Trailers B62D 65/024 (20130101) B62D 65/026 (20130101) Ships or Other Waterborne Vessels; Equipment for Shipping B63B 73/30 (20200101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/10 (20170101) Technical Subjects Covered by Former US Classification Y10T 29/49895 (20150115) Y10T 29/53539 (20150115) Y10T 29/53543 (20150115) Y10T 29/53548 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059855 | Parker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jason Parker (Grafton, Massachusetts); Tony Kayhart (Cambridge, Massachusetts); Damian Kubiak (Marlborough, Massachusetts); Robert Sykes (Burlington, Massachusetts) |
| ABSTRACT | A method of forming a net shape preform for a high performance ballistic helmet includes preparing one or more full prepreg plies, preparing one or more filler prepreg plies, wherein a shape and orientation of one filler prepreg ply of the one or more filler prepreg plies is different from a shape and orientation of another filler prepreg ply of the one or more filler prepreg plies, layering the one or more full prepreg plies with one or more filler prepreg plies to form a ply stack and deforming a portion of the ply stack while constraining the ply stack by applying in-plane tensional force to the ply stack to form the net-shape preform. |
| FILED | Wednesday, September 23, 2020 |
| APPL NO | 17/029117 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/56 (20130101) Original (OR) Class B29C 70/465 (20130101) B29C 2793/0081 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2077/10 (20130101) B29K 2105/0881 (20130101) B29K 2307/04 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/768 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 1/08 (20130101) F41H 5/0485 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059953 | Embler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Jonathan David Embler (Santa Ana, California); John Matthew Nichols (Madison, Alabama); Glenn William Torres (Madison, Alabama); Jacob Ryan Szczudlak (Madison, Alabama); William Preston Keith (Lakewood, California); Tin Anh Luu (Garden Grove, California); Morgan Ashley Lewis (Huntington Beach, California); Keith Charles Kreutztrager (St. Charles, Missouri); Jonathan Edward Toomey (Orange, California); Juan Carlos Guzman (Seattle, Washington) |
| ABSTRACT | A composite tank for a reusable launch vehicle comprises a composite wall, having a first coefficient of thermal expansion. The composite wall comprises a first end, a second end, a central axis, which passes through the first end and through the second end, and a cylindrical interior surface. The composite tank also comprises slosh baffles, formed from a second material, having a second coefficient of thermal expansion that is different from the first coefficient of thermal expansion. Each of the slosh baffles is attached to the cylindrical interior surface of the composite wall. Each of the slosh baffles is annular and is separated from the cylindrical interior surface of the composite wall by a radial gap, selected, in part, based on a difference between the first coefficient of thermal expansion and the second coefficient of thermal expansion. The radial gap is configured to change responsive to changes in temperature of the composite tank. |
| FILED | Wednesday, August 18, 2021 |
| APPL NO | 17/405509 |
| ART UNIT | 3733 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 15/077 (20130101) Original (OR) Class B60K 2015/0777 (20130101) B60K 2015/03486 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060270 | Tour et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | James M. Tour (Bellaire, Texas); Rodrigo Villegas Salvatierra (Houston, Texas); Dante Zakhidov (McKinney, Texas); Junwei Sha (Tianjin, China PRC) |
| ABSTRACT | Embodiments of the present disclosure pertain to methods of making a carbon nanotube hybrid material by depositing a catalyst solution onto a carbon-based material, and growing carbon nanotubes on the carbon-based material such that the grown carbon nanotubes become covalently linked to the carbon-based material through carbon-carbon bonds. The catalyst solution includes a metal component (e.g., iron) and a buffer component (e.g., aluminum) that may be in the form of particles. The metal component of the particle may be in the form of a metallic core or metallic oxide core while the buffer component may be on a surface of the metal component in the form of metal or metal oxides. Further embodiments of the present disclosure pertain to the catalytic particles and carbon nanotube hybrid materials. The carbon nanotube hybrid materials of the present disclosure may be incorporated as electrodes (e.g., anodes or cathodes) in energy storage devices. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 16/811183 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 23/72 (20130101) B01J 23/745 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/16 (20170801) C01B 32/162 (20170801) Original (OR) Class C01B 2202/22 (20130101) C01B 2202/32 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/12 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/36 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/96 (20130101) H01M 4/139 (20130101) H01M 4/362 (20130101) H01M 4/0428 (20130101) H01M 4/583 (20130101) H01M 4/587 (20130101) H01M 4/663 (20130101) H01M 4/9083 (20130101) H01M 2004/021 (20130101) H01M 2004/027 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/742 (20130101) Y10S 977/843 (20130101) Y10S 977/948 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060499 | Rowan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stuart J. Rowan (Chicago, Illinois); Elvis Cudjoe (Cleveland Heights, Ohio) |
| ABSTRACT | A dynamic cross-linked polymer nanocomposite adhesive has been developed by the oxidation of a thiol functionalized semi-crystalline and/or amorphous oligomer and thiol functionalized Cellulose Nanocrystals (CNCs) to form a polydisulfide network. The resulting solid material has a melting point transition at ca. 75° C. which corresponds to the melting of the semi-crystalline and/or amorphous phase of the nanocomposite adhesive. At higher temperatures (ca. 150° C.), results in the dynamic behavior of the disulfide bond being induced, where the bonds break and reform. Two levels of adhesion are obtained, in some embodiment by (1) heating the adhesive material to 80° C. (melting the semi-crystalline and/or amorphous phase) resulting in a lower modulus/viscosity of the adhesive, thus allowing better surface wetting on a substrate and (2) heating the adhesive material to 150° C. (inducing dynamic behavior of disulfide bonds), further lowers the modulus/viscosity of the adhesive ensuring a much better surface wetting and stronger adhesive bond. The polymer adhesive has been demonstrated to bind to, relatively high surface energy substrates including metal and hydrophilic glass, and to low surface energy substrates such as hydrophobic glass. |
| FILED | Monday, May 07, 2018 |
| APPL NO | 16/610985 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 101/08 (20130101) Original (OR) Class C09J 181/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060559 | Niu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CZ Biohub SF LLC (San Francisco, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | CZ Biohub SF, LLC (San Francisco, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Jia Niu (Stanford, California); Chelsea Lyons Gordon (Stanford, California); Hyongsok Tom Soh (San Francisco, California) |
| ABSTRACT | The disclosure is directed to methods and compositions for screening a library of aptamers for aptamers having a binding affinity to a target molecule. Specifically, non-natural nucleotides can be introduced onto aptamers immobilized on the surface of beads. The non-natural nucleotides can then be subsequently chemically modified to include additional binding agents. For example, copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions can be used to introduce a wide range of binding agents onto non-natural nucleotides on beads. |
| FILED | Wednesday, June 19, 2019 |
| APPL NO | 15/734522 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2320/13 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6811 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060619 | Tavazoie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | THE ROCKEFELLER UNIVERSITY (New York, New York) |
| INVENTOR(S) | Sohail Tavazoie (New York, New York); Nils Halberg (Brooklyn, New York); Kim Png (New York, New York) |
| ABSTRACT | This invention concerns pathological angiogenesis and cancer, related treatment methods, and related compositions. Also disclosed are related diagnosis kits and methods. |
| FILED | Monday, January 04, 2021 |
| APPL NO | 17/140409 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/18 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1135 (20130101) C12N 2310/113 (20130101) C12N 2310/141 (20130101) C12N 2320/11 (20130101) C12N 2320/12 (20130101) C12N 2330/31 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/106 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060627 | Na et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Suok-Min Na (Laurel, Maryland); Nicholas J. Jones (Fairfax, Virginia); Paul K. Lambert (Columbia, Maryland) |
| ABSTRACT | High entropy alloys (HEAs) are provided, which exhibit hard magnetic properties, including increased saturation magnetization, improved coercivity, and thermal stability at temperatures exceeding about 200° C. Methods of making the HEAs are also provided, as well as methods for using the HEAs, particularly in extreme environments. |
| FILED | Thursday, October 28, 2021 |
| APPL NO | 17/513130 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 1/02 (20130101) C22C 30/02 (20130101) Original (OR) Class Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060852 | Nemanick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | Eric Joseph Nemanick (Santa Monica, California); Andrea Hsu (El Segundo, California); John Schilling (Lancaster, California); John Desain (Redondo Beach, California); Brian Brady (Seal Beach, California); Andrew Cortopassi (Running Springs, California) |
| ABSTRACT | Solid rocket motors are provided herein. In certain embodiments, a solid rocket motor includes a housing containing thin layers of fuel and thin layers of an inert oxidizer, separated by a thin nonconductive layer. The housing has a nozzle at the end for gas release and channeling. Prior to use, the inert oxidizer is activated by electrochemical oxidation which can generate an active oxidizer and additional fuel. Ignition of the oxidizer and fuel can be triggered whereby the contents of the housing can ignite, generating hot gasses to be channeled out through the nozzle to generate thrust. Replacing current state solid rocket motors with embodiments described herein can improve cost, safety and increase capability. The disclosed embodiments can be safe to transport, store, and handle. Additionally, there can be no moving parts unlike hybrid or liquid rocket motors. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/454691 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Jet-propulsion Plants F02K 9/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060868 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Na Li (Richardson, Texas); Carter S. Haines (Murphy, Texas); Marcio D. Lima (Richardson, Texas); Monica Jung DeAndrade (Richardson, Texas); Shaoli Fang (Richardson, Texas); Jiyoung Oh (Richardson, Texas); Mikhail E. Kozlov (Dallas, Texas); Dongseok Suh (Plano, Texas); Ray H. Baughman (Dallas, Texas) |
| ABSTRACT | Actuators (artificial muscles) comprising twisted polymer fibers generate tensile actuation when powered thermally. In some embodiments, the thermally-powered polymer fiber tensile actuator can be incorporated into an article, such as a textile or garment. |
| FILED | Monday, October 18, 2021 |
| APPL NO | 17/504305 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/00 (20130101) Spinning or Twisting D01H 1/10 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/02 (20130101) D02G 3/26 (20130101) D02G 3/448 (20130101) Braiding or Manufacture of Lace, Including Bobbin-net or Carbonised Lace; Braiding Machines; Braid; Lace D04C 1/02 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/046 (20130101) D10B 2401/061 (20130101) D10B 2509/00 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/06 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 10/00 (20130101) H02N 11/006 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2925 (20150115) Y10T 428/249921 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060901 | Wiedemeier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Brandon J. Wiedemeier (San Diego, California); Jeffrey M. Lloyd (San Diego, California); Salvador Serra (Spring Valley, California) |
| ABSTRACT | A pressure locking clamp includes a base, a hook arm, and a clasp arm. An imaginary central plane divides the base into a first and second half. The hook arm pivots on the first half of the base around a first axis parallel to the imaginary central plane. The clasp arm pivots on the second half of the base around a second axis parallel to the imaginary central plane. The hook and clasp arms each includes a lock contact area. In a closed state of the pressure locking clamp, the hook and clasp arms and the base together form an eye enclosure. In the closed state, pressure inside the eye enclosure presses the lock contact area of the clasp arm against the lock contact area of the hook arm, and this inhibits the hook and clasp arms from pivoting away from each other, reinforcing the eye enclosure. |
| FILED | Tuesday, February 21, 2023 |
| APPL NO | 18/172135 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 2/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061187 | Birnbaum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael Birnbaum (Cambridge, Massachusetts); Connor Dobson (Somerville, Massachusetts) |
| ABSTRACT | Compositions of retroviruses and methods of using the same for gene delivery, wherein the retroviruses comprise a viral envelope protein comprising at least one mutation that diminishes its native function, a non-viral membrane-bound protein comprising a membrane-bound domain and an extracellular targeting domain. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 16/826665 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 14/4748 (20130101) C07K 14/5437 (20130101) C07K 14/70532 (20130101) C07K 14/70539 (20130101) C07K 16/2803 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/035 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2740/15045 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061188 | Birnbaum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael Birnbaum (Arlington, Massachusetts); Connor Dobson (Somerville, Massachusetts) |
| ABSTRACT | Compositions of retroviruses and methods of using the same for gene delivery, wherein the retroviruses comprise a viral envelope protein comprising at least one mutation that diminishes its native function, a non-viral membrane-bound protein comprising a membrane-bound domain and an extracellular targeting domain. |
| FILED | Wednesday, August 30, 2023 |
| APPL NO | 18/458628 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/005 (20130101) C07K 14/4748 (20130101) C07K 14/5437 (20130101) C07K 14/70532 (20130101) C07K 14/70539 (20130101) C07K 16/2803 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/035 (20130101) C07K 2319/60 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2740/15045 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/505 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061260 | Russo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Analog Photonics LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | Analog Photonics LLC (Boston, Massachusetts) |
| INVENTOR(S) | Peter Nicholas Russo (Somerville, Massachusetts); Christopher Vincent Poulton (Cambridge, Massachusetts); Matthew Byrd (Arlington, Massachusetts); Zhan Su (Boston, Massachusetts); Ehsan Hosseini (Boston, Massachusetts); Michael Robert Watts (Hingham, Massachusetts) |
| ABSTRACT | At least one beam of an optical wave is transmitted along a transmission angle toward a target location from a send aperture of a transmitter. The optical wave comprises at least a first portion, and a second portion having a different characteristic from a characteristic of the first portion. Two or more receivers include at least one receiver comprising: a receive aperture arranged in proximity to at least one of the send aperture or a receive aperture of a different receiver, an optical phased array within the receive aperture, the optical phased array being configured to receive at least a portion of a collected optical wave arriving at the receive aperture along a respective collection angle, and a filter configured to filter the received portion of the collected optical wave according to the characteristic of the first portion of the optical wave. |
| FILED | Friday, October 28, 2022 |
| APPL NO | 17/975834 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4815 (20130101) G01S 7/4816 (20130101) G01S 7/4911 (20130101) G01S 7/4918 (20130101) G01S 17/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061271 | Allen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | David W. Allen (Fairfax, Virginia) |
| ABSTRACT | A system and method for periodically varying a center frequency for assured time transfer in order to securely transfer a signal from a source to a receiver, without adding additional encryption to signal. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 17/529657 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/215 (20130101) Original (OR) Class Radio-controlled Time-pieces G04R 20/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061673 | Soleyman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
| INVENTOR(S) | Sean Soleyman (Calabasas, California); Deepak Khosla (Camarillo, California) |
| ABSTRACT | Described is a system for controlling multiple autonomous platforms. A training process is performed to produce a trained learning agent in a simulation environment. In each episode, each controlled platform is assigned to one target platform that produces an observation. A learning agent processes the observation using a deep learning network and produces an action corresponding to each controlled platform until an action has been produced for each controlled platform. A reward value is obtained corresponding to the episode. The trained learning agent is executed to control each autonomous platform, where the trained agent receives one or more observations from one or more platform sensors and produces an action based on the one or more observations. The action is then used to control one or more platform actuators. |
| FILED | Wednesday, February 03, 2021 |
| APPL NO | 17/167001 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Electric Digital Data Processing G06F 18/2185 (20230101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061977 | Nestler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Analog Devices, Inc. (Wilmington, Massachusetts) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Eric G. Nestler (Beach Haven, New Jersey); Naveen Verma (Princeton, New Jersey); Hossein Valavi (Princeton, New Jersey) |
| ABSTRACT | Systems and methods are provided for reducing power in in-memory computing, matrix-vector computations, and neural networks. An apparatus for in-memory computing using charge-domain circuit operation includes transistors configured as memory bit cells, transistors configured to perform in-memory computing using the memory bit cells, capacitors configured to store a result of in-memory computing from the memory bit cells, and switches, wherein, based on a setting of each of the switches, the charges on at least a portion of the plurality of capacitors are shorted together. Shorting together the plurality of capacitors yields a computation result. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675617 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) G06N 3/048 (20230101) G06N 3/061 (20130101) G06N 3/065 (20230101) Original (OR) Class Static Stores G11C 11/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061982 | O'Shea |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Timothy James O'Shea (Arlington, Virginia) |
| ABSTRACT | Methods, systems, and apparatus, including computer programs encoded on a storage medium, for processing radio signals. In once aspect, a system is disclosed that includes a processor and a storage device storing computer code that includes operations. The operations may include obtaining first output data generated by a first neural network based on the first neural network processing a received radio signal, receiving, by a signal transformer, a second set of input data that includes (i) the received radio signal and (ii) the first output data, generating, by the signal transformer, data representing a transformed radio signal by applying one or more transforms to the received radio signal, providing the data representing the transformed radio signal to a second neural network, obtaining second output data generated by the second neural network, and determining based on the second output data a set of information describing the received radio signal. |
| FILED | Friday, October 07, 2022 |
| APPL NO | 17/962007 |
| ART UNIT | 2641 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 3/045 (20230101) Transmission H04B 1/0003 (20130101) H04B 17/309 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062174 | Usumezbas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Anil Usumezbas (North Brunswick, New Jersey); Bogdan Calin Mihai Matei (Princeton, New Jersey); Rakesh Kumar (West Windsor, New Jersey); Supun Samarasekera (Skillman, New Jersey) |
| ABSTRACT | A method, machine readable medium and system for semantic segmentation of 3D point cloud data includes determining ground data points of the 3D point cloud data, categorizing non-ground data points relative to a ground surface determined from the ground data points to determine legitimate non-ground data points, segmenting the determined legitimate non-ground and ground data points based on a set of common features, applying logical rules to a data structure of the features built on the segmented determined non-ground and ground data points based on their spatial relationships and incorporated within a machine learning system, and constructing a 3D semantics model from the application of the logical rules to the data structure. |
| FILED | Wednesday, September 15, 2021 |
| APPL NO | 17/476377 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/40 (20130101) G06T 7/10 (20170101) Original (OR) Class G06T 17/205 (20130101) G06T 2207/10028 (20130101) G06T 2207/20072 (20130101) G06T 2207/20081 (20130101) G06T 2207/20221 (20130101) G06T 2207/30181 (20130101) G06T 2210/56 (20130101) Image or Video Recognition or Understanding G06V 10/776 (20220101) G06V 20/70 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062186 | Chiu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Han-Pang Chiu (West Windsor, New Jersey); Junjiao Tian (Atlanta, Georgia); Zachary Seymour (Pennington, New Jersey); Niluthpol C. Mithun (Lawrenceville, New Jersey); Alex Krasner (Princeton, New Jersey); Mikhail Sizintsev (Princeton, New Jersey); Abhinav Rajvanshi (Plainsboro, New Jersey); Kevin Kaighn (Medord, New Jersey); Philip Miller (Yardley, New Jersey); Ryan Villamil (Plainsboro, New Jersey); Supun Samarasekera (Skillman, New Jersey) |
| ABSTRACT | A method, machine readable medium and system for RGBD semantic segmentation of video data includes determining semantic segmentation data and depth segmentation data for less than all classes for images of each frame of a first video, determining semantic segmentation data and depth segmentation data for images of each key frame of a second video including a synchronous combination of respective frames of the RGB video and the depth-aware video in parallel to the determination of the semantic segmentation data and the depth segmentation data for each frame of the first video, temporally and geometrically aligning respective frames of the first video and the second video, and predicting semantic segmentation data and depth segmentation data for images of a subsequent frame of the first video based on the determination of the semantic segmentation data and depth segmentation data for images of a key frame of the second video. |
| FILED | Thursday, October 07, 2021 |
| APPL NO | 17/496403 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/40 (20130101) G06T 7/38 (20170101) G06T 7/50 (20170101) G06T 7/174 (20170101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/10024 (20130101) G06T 2207/20112 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062732 | King et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Arlington, Virginia) |
| INVENTOR(S) | Richard R. King (Thousand Oaks, California); Christopher M. Fetzer (Valencia, California); Daniel C. Law (Arcadia, California); Xing-Quan Liu (Arcadia, California); William D. Hong (Los Angeles, California); Kenneth M. Edmondson (Burbank, California); Dimitri D. Krut (Encino, California); Joseph C. Boisvert (Thousand Oaks, California); Nasser H. Karam (La Canada, California) |
| ABSTRACT | In one aspect, optoelectronic devices are described herein. In some implementations, an optoelectronic device comprises a photovoltaic cell. The photovoltaic cell comprises a space-charge region, a quasi-neutral region, and a low bandgap absorber region (LBAR) layer or an improved transport (IT) layer at least partially positioned in the quasi-neutral region of the cell. |
| FILED | Monday, August 12, 2019 |
| APPL NO | 16/538733 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0352 (20130101) H01L 31/0687 (20130101) H01L 31/0725 (20130101) Original (OR) Class H01L 31/0735 (20130101) H01L 31/035209 (20130101) H01L 31/035218 (20130101) H01L 31/035227 (20130101) H01L 31/035272 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/544 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12063068 | Utter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | Alexander Clifton Utter (Hawthorne, California); Chang Lee (Yorba Linda, California) |
| ABSTRACT | A tracking system includes one or more cameras and machine-vision processors configured to track the position of a plurality of optical tracking emitters. Each of the plurality of tracking emitters is modulated with a message. The message includes identification information for any of the plurality of tracking cameras receiving the message, so that the cameras can track the location of each emitter. |
| FILED | Monday, March 08, 2021 |
| APPL NO | 17/195529 |
| ART UNIT | 2634 — Digital Communications |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 1/7038 (20190801) Transmission H04B 10/11 (20130101) H04B 10/114 (20130101) H04B 10/116 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12063073 | Estrella |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Freedom Photonics LLC (Goleta, California) |
| ASSIGNEE(S) | Freedom Photonics LLC (Goleta, California) |
| INVENTOR(S) | Steven Brian Estrella (Santa Barbara, California) |
| ABSTRACT | Various designs of optical interconnects and optical links may comprise one or more optically resonant electro-optical modulators used to modulate one or more optical carriers received from one or more lasers using one or more electronic input signals. A wavelength of each laser may be dynamically tuned using a control signal generated by a feedback control system to stabilize the electro-optical modulation of the optical carriers. |
| FILED | Wednesday, March 23, 2022 |
| APPL NO | 17/656193 |
| ART UNIT | 2635 — Digital Communications |
| CURRENT CPC | Transmission H04B 10/503 (20130101) H04B 10/572 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12063095 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Gov of the US as Rep by the Secy of the Air Force (Wright Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Joseph Anderson (Edwards, California); Nicholas Black (Charlotte, North Carolina); Michael Anderson (Colorado Springs, Colorado) |
| ABSTRACT | A repeater for maintaining wireless line of sight communications. The repeater is autonomously repositional in both absolute location and azimuthal orientation. The repeater has at least two vibratory motors, or other vibration sources, which provide oscillations to depending legs against a support surface. By selectively operating one or more of the vibration sources together or independently, the repeater may be moved as helpful to maintain line of sight communication with another repeater or other operational hardware. A command signal from a remote base station controls the locomotion of the repeater to provide both a change in absolute position relative to the surroundings and a rotational change in azimuthal orientation as necessary to maintain communication under dynamic conditions. |
| FILED | Monday, October 30, 2023 |
| APPL NO | 18/497680 |
| ART UNIT | 2644 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 7/155 (20130101) Original (OR) Class H04B 7/2606 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12059698 | Fedorov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Andrei G. Fedorov (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present disclosure provide for methods and systems for making structures using an electrospray system while under vacuum. In particular, embodiments of the present disclosure provide for methods and systems for ultra-fast growth of high aspect ratio nano/meso/micro-structures with three dimensional topological complexity and control of phase and composition of the structure formed. |
| FILED | Tuesday, January 24, 2023 |
| APPL NO | 18/158666 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 5/16 (20130101) Original (OR) Class B05B 5/035 (20130101) B05B 5/0255 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/04 (20130101) B05D 3/068 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/145 (20190501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059703 | Britt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MATRIX SENSORS, INC. (San Diego, California) |
| ASSIGNEE(S) | MATRIX SENSORS, INC. (San Diego, California) |
| INVENTOR(S) | David K Britt (El Cerrito, California); Paul R Wilkinson (El Segundo, California); Steven Yamamoto (San Diego, California) |
| ABSTRACT | A method is provided for coating a surface of a material with a film of porous coordination polymer. A first substrate having a first surface to be coated is positioned in a processing chamber such that the first surface is placed in an opposing relationship to a second surface. The second surface may be provided by a wall of the processing chamber, or in some cases the second surface may be provided by a second substrate to be coated. The first substrate is held such that a gap exists between the first and second surfaces, and the gap is filled with at least one reaction mixture comprising reagents sufficient to form the crystalline film on at least the first surface. A thin gap (e.g., less than 2 mm) between the first and second surfaces is effective for producing a high quality film having a thickness less than 100 μm. Confining the volume of the reaction mixture to a thin layer adjacent the substrate surface significantly reduces problems with sedimentation and concentration control. The size, shape, or average thickness of the gap may be adjusted during formation of the film in response to feedback from at least one film growth monitor. |
| FILED | Wednesday, September 15, 2021 |
| APPL NO | 17/476469 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Apparatus for Applying Fluent Materials to Surfaces, in General B05C 5/004 (20130101) Original (OR) Class B05C 5/0225 (20130101) B05C 11/1005 (20130101) B05C 13/02 (20130101) B05C 15/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/022 (20130101) G01N 2291/0426 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059727 | Elliott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); NORTH CAROLINA A and T STATE UNIVERSITY (Greensboro, North Carolina) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oakridge, Tennessee); NORTH CAROLINA A and TSTATE UNIVERSITY (Greensboro, North Carolina) |
| INVENTOR(S) | Amelia M. Elliott (Knoxville, Tennessee); Sun Yi (Greensboro, North Carolina); Sameer Hamoush (Greensboro, North Carolina); M A Muktadir (Greensboro, North Carolina); Sarita Sepulveda (Waynesville, North Carolina) |
| ABSTRACT | Systems and methods for additive manufacturing of objects are disclosed. The system includes an object builder subsystem configured to additively manufacture an object in a powder bed, an object extraction subsystem configured to extract the object from the powder bed, and a depowdering subsystem configured to remove powder from the object while the object is gripped by the gripper assembly. The object extraction subsystem includes a gripper assembly comprising two or more gripper members that each include a perforated mesh structure. |
| FILED | Friday, October 13, 2023 |
| APPL NO | 18/379829 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/73 (20210101) B22F 10/85 (20210101) B22F 12/88 (20210101) Original (OR) Class B22F 12/90 (20210101) B22F 2998/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 40/00 (20141201) B33Y 50/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060272 | Xing et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yangchuan Xing (Columbia, Missouri); Ahmed M. Jasim (Columbia, Missouri) |
| ASSIGNEE(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| INVENTOR(S) | Yangchuan Xing (Columbia, Missouri); Ahmed M. Jasim (Columbia, Missouri) |
| ABSTRACT | A method is disclosed for forming nanoscale coatings on a solid substrate surface. In certain embodiments, the method includes the following steps: contacting a substrate with a first liquid organic solvent; adding a liquid agent to the first liquid organic solvent to form a liquid agent film on a surface of the substrate; and adding the nanocoating precursor in the first liquid organic solvent to react the nanocoating precursor with the liquid agent to form the nanocoating on the surface of the substrate. |
| FILED | Friday, January 11, 2019 |
| APPL NO | 16/960214 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/168 (20170801) Original (OR) Class Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/42 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/88 (20130101) C01P 2004/64 (20130101) C01P 2004/86 (20130101) C01P 2006/40 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/24 (20130101) C09C 1/56 (20130101) C09C 1/3661 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 4/366 (20130101) H01M 4/523 (20130101) H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060415 | Pasqualini et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Renata Pasqualini (New Brunswick, New Jersey); Wadih Arap (New Brunswick, New Jersey); Fernanda Iamassaki Staquicini (New Brunswick, New Jersey); Fortunato Ferrara (Santa Fe, New Mexico); Sara D'Angelo (Santa Fe, New Mexico); Andrew R. M. Bradbury (Santa Fe, New Mexico) |
| ABSTRACT | Isolated or recombinant EphA5 or GRP78 targeting antibodies are provided. In some cases, antibodies of the embodiments can be used for the detection, diagnosis and/or therapeutic treatment of human diseases, such as cancer. A method of rapidly identifying antibodies or antibody fragments for the treatment of cancer using a combination of in vitro and in vivo methodologies is also provided. |
| FILED | Friday, February 04, 2022 |
| APPL NO | 17/592828 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/07 (20130101) A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 47/6803 (20170801) A61K 47/6817 (20170801) A61K 47/6843 (20170801) A61K 47/6849 (20170801) A61K 47/6891 (20170801) A61K 49/0008 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/47 (20130101) C07K 16/005 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 16/28 (20130101) C07K 16/30 (20130101) C07K 16/2866 (20130101) C07K 16/3023 (20130101) C07K 2317/21 (20130101) C07K 2317/35 (20130101) C07K 2317/55 (20130101) C07K 2317/73 (20130101) C07K 2317/77 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/64 (20130101) C12N 15/1037 (20130101) C12N 2810/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5011 (20130101) G01N 33/57423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060483 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Twelve Benefit Corporation (Berkeley, California) |
| ASSIGNEE(S) | Twelve Benefit Corporation (Berkeley, California) |
| INVENTOR(S) | Lihui Wang (Berkeley, California); Ziyang Huo (Moraga, California); Chengtian Shen (Irvine, California) |
| ABSTRACT | Provided are compositions including a core moiety and a plurality of polymeric units, in which at least one of these can include an ionizable moiety or an ionic moiety. The core moiety may be a multivalent core moiety, trivalent core moiety, tetravalent core moiety, pentavalent core moiety, or multivalent arylene moiety. Materials, electrochemical cells, and methods using such compositions are also described. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/451630 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) C08G 2261/17 (20130101) C08G 2261/45 (20130101) C08G 2261/132 (20130101) C08G 2261/143 (20130101) C08G 2261/146 (20130101) C08G 2261/164 (20130101) C08G 2261/312 (20130101) C08G 2261/3142 (20130101) C08G 2270/00 (20130101) Compositions of Macromolecular Compounds C08L 65/00 (20130101) Original (OR) Class C08L 2312/00 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/23 (20210101) C25B 13/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060507 | Zaitseva et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Natalia P. Zaitseva (Livermore, California); M Leslie Carman (San Ramon, California); Andrew M. Glenn (Livermore, California); Andrew Neil Mabe (Livermore, California) |
| ABSTRACT | A scintillator material includes a polymer matrix, a primary dye in the polymer matrix, the primary dye being a fluorescent dye; a secondary dye, and a Li-containing compound in the polymer matrix, where the Li-containing compound is a Li salt of a short-chain aliphatic acid. In addition, the scintillator material exhibits an optical response signature for thermal neutrons that is different than an optical response signature for fast neutrons. |
| FILED | Thursday, April 08, 2021 |
| APPL NO | 17/225429 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 69/109 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) Original (OR) Class C09K 2211/1088 (20130101) Measurement of Nuclear or X-radiation G01T 1/2006 (20130101) G01T 1/2033 (20130101) G01T 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061069 | Barr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Christian G. Barr (Kansas City, Missouri); Ben Brown (Kansas City, Missouri); John Porter (Kansas City, Missouri); Gregory John Vernon (Kansas City, Missouri) |
| ABSTRACT | A multi-layer armor plate comprises a strike plate, a structural mesh layer, an outer skin, a compliant mesh layer, and an inner skin layer. The strike plate has an outer surface and an inner surface. The structural mesh layer is positioned on the outer surface of the strike plate and includes lattice structure with a first structural compliance. The outer skin layer is positioned over the structural mesh layer. The compliant mesh layer is positioned on the inner surface and includes lattice structure with a second structural compliance that is greater than the first structural compliance. The inner skin layer is positioned over the compliant mesh layer. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734589 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 5/0457 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061083 | Previsic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Re Vision Consulting, LLC (Sacramento, California) |
| ASSIGNEE(S) | RE VISION CONSULTING, LLC (Sacramento, California) |
| INVENTOR(S) | Mirko Previsic (Sacramento, California); Ravi Challa (Sacramento, California); Anantha Karthikeyan (Sacramento, California) |
| ABSTRACT | A method and system for prediction of wave properties include collecting time series data streams from one or more wave measurement devices and processing the data using a wave-prediction algorithm to identify the frequency components of the data and compute wave parameters. The wave-field is propagated in space and time to predict wave height, speed, and velocity at a target location. A sliding window approach is used to continuously update the prediction in real-time. |
| FILED | Monday, March 02, 2020 |
| APPL NO | 17/435684 |
| ART UNIT | 3617 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 13/002 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 1/0206 (20130101) Electric Digital Data Processing G06F 30/28 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061249 | Loui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Hung Loui (Albuquerque, New Mexico); Brianna N. Maio (Albuquerque, New Mexico); Steven Castillo (Peralta, New Mexico); Emmett J. Gurule (Albuquerque, New Mexico) |
| ABSTRACT | Various technologies pertaining to forming a very high instantaneous bandwidth (IBW) radar signal based upon several radio frequency (RF) signals that have sub-bands of the frequency band of the radar signal are described herein. A radar system is configured to address local oscillator leakage across multiple transmit channels of the radar system, such that the radar signal has a relatively constant or other desired amplitude and phase across frequencies of the radar signal. In addition, the radar system is configured to compute a correction signal that pre-distorts each of the sub-frequency channels such that upon combining enables the generation of desired amplitude and phase response across a transmitted pulse. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 17/522385 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/038 (20130101) G01S 13/0209 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061365 | Neidigk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Stephen Neidigk (Albuquerque, New Mexico); Thomas M. Rice (Albuquerque, New Mexico) |
| ABSTRACT | A system or method for a magnetic self-aligning coupling device for a fiber optic cable. The device includes a first end coupling comprising a first magnet and a second magnet. Both magnets include a mating surface and an annular ring defining an axial aperture. The aperture receives a distal end of a segment of fiber optic cable in a tight fit. The fiber optic cable has an exterior sleeve and a fiber core. The fiber core of the first segment and the second segment of the fiber optic cable are axially aligned by magnetic force in the first and second apertures to create a continuous fiber optic path. A method for detecting a security breach of a door using the self-aligning couplings is also described. |
| FILED | Wednesday, February 01, 2023 |
| APPL NO | 18/104693 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 8/16 (20130101) Optical Elements, Systems, or Apparatus G02B 6/354 (20130101) G02B 6/3572 (20130101) G02B 6/3886 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062461 | Welter |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NuScale Power, LLC (Portland, Oregon) |
| ASSIGNEE(S) | NuScale Power, LLC (Corvallis, Oregon) |
| INVENTOR(S) | Kent Welter (Corvallis, Oregon) |
| ABSTRACT | Supports with integrated sensors for nuclear reactor steam generators, and associated systems and methods, are disclosed. A representative method for forming a nuclear-powered steam generator includes forming an instrumented support, the instrumented support including a carrier portion and a retainer portion, with at least one of the carrier portion or the retainer portion being integrally formed with a sensor via an additive manufacturing process. The method can further include coupling the sensor to a communication link, supporting a helical steam conduit on the instrumented support, and installing the helical steam conduit and the instrumented support in a nuclear reactor. The helical steam conduit is positioned along a primary flow path, which is in turn positioned to circulate a heated primary flow in thermal communication with the helical steam conduit. |
| FILED | Thursday, February 04, 2021 |
| APPL NO | 17/168118 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Methods of Steam Generation; Steam Boilers F22B 1/162 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 7/02 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 9/00 (20130101) Nuclear Reactors G21C 15/182 (20130101) G21C 17/102 (20130101) G21C 17/112 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062464 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | David C. Anderson (Knoxville, Tennessee); Anibal J. Ramirez-Cuesta (Knoxville, Tennessee); Matthew B. Stone (Oak Ridge, Tennessee); Amelia M. Elliott (Cleveland, Tennessee); Derek H. Siddel (Knoxville, Tennessee) |
| ABSTRACT | Collimators and other components for use in neutron scattering experiments or to provide neutron shielding in nuclear reactors or accelerator based neutron sources are produced by additive manufacturing from neutron absorbing material, such as boron carbide (B4C) or isotopically enriched boron carbide (10B). |
| FILED | Monday, August 01, 2022 |
| APPL NO | 17/878172 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Nuclear Reactors G21C 11/028 (20130101) Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 1/00 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 4/02 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/046 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062465 | Said et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Ayman H. Said (Lombard, Illinois); Thomas Gog (Woodridge, Illinois); Jung Ho Kim (Naperville, Illinois); Emily K. Aran (Westchester, Illinois) |
| ABSTRACT | The invention provides a method for fabricating analyzers, the method comprising providing a radiation manipulating material on a first surface of a flexible support; contacting a second surface of the flexible support to a permeable mold, wherein the mold has a first flexible support contact surface and a second surface; and applying negative pressure to the second side of the flexible support to cause the flexible support to conform to the first flexible support contact surface of the mold. Also provided is a system for fabricating crystal analyzers, the system comprising crystal structures reversibly attached to a flexible support; a porous mold reversibly contacting the flexible support, wherein the mold defines a topography; and a negative pressure applied to the flexible support to cause the crystal structures to conform to the topography. |
| FILED | Friday, August 19, 2022 |
| APPL NO | 17/892020 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/06 (20130101) Original (OR) Class G21K 2201/062 (20130101) G21K 2201/064 (20130101) G21K 2201/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062790 | Jun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Gyeonggi-Do, South Korea); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); LAWRENCE BERKELEY NATIONAL LABORATORY (Berkeley, California) |
| INVENTOR(S) | KyuJung Jun (Albany, California); Gerbrand Ceder (Orinda, California); Yingzhi Sun (Albany, California); Yan Wang (Brookline, Massachusetts); Lincoln Miara (Lincoln, Massachusetts); Yan Zeng (Albany, California); Yihan Xiao (Berkeley, California) |
| ABSTRACT | A solid-state ion conductor including a compound of Formula 1: Li(3+2y1)B(P1-y1A1y1O4)2 Formula 1 wherein, in Formula 1, A1 is an element of Groups 4, 14, or a combination thereof, and has an oxidation state of +4, and 0<y1<1. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/321714 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/5825 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062834 | Young et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Barbara Diane Young (Raymore, Missouri); Steven James Sedlock (Raymore, Missouri); Kevin Christopher Ledden (Raymore, Missouri); Alan Ahlberg Elliot (Lees Summit, Missouri) |
| ABSTRACT | A method for tuning a resonant frequency of wireless communication circuitry on a multichip module including a plurality of chips includes applying an electrical insulator to an upper surface of the multichip module; creating a plurality of openings in the electrical insulator, each opening being positioned at a successive one of the bond pads to be electrically connected to create a plurality of exposed bond pads; applying metal to each exposed bond pad to form a successive one of a plurality of interconnect bases; removing a portion of the layer of photoresist to create a plurality of bridge supports, each bridge support positioned between a successive pair of interconnect bases; applying metal to each bridge support and associated interconnect bases to form a successive one of the interconnect traces; removing the bridge supports; and disconnecting one or more of the interconnect traces as necessary to obtain a target resonant frequency. |
| FILED | Wednesday, September 06, 2023 |
| APPL NO | 18/461654 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 1/422 (20130101) H01Q 1/2283 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062926 | Babakhani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Hamed Rahmani (Belle Mead, New Jersey); Hidemasa Mitsui (Santa Clara, California) |
| ABSTRACT | Systems and methods for utilizing a small form-factor, wirelessly powered transceiver are disclosed. In one embodiment, a wireless powered transceiver includes a receive antenna configured to receive a receive signal, a transmit antenna configured to transmit a transmit signal, a power harvesting system including a rectifier circuit configured convert radio frequency energy from the receive signal into DC (direct current) voltage, and a power management unit (PMU) configured to set the operating mode and biasing condition of the receive and transmit circuitry blocks and provide DC voltage from the receive circuitry block to the transmit circuitry block to maintain a minimum voltage, a receiver circuitry block configured to provide energy from the receive signal to the power harvesting system, and a transmitter circuitry block including a data modulator circuit, the data modulator circuit configured to generate the transmit signal using DC voltage received from the power management unit. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/929959 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/001 (20200101) H02J 50/27 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12063461 | Galambos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Paul C. Galambos (Albuquerque, New Mexico); Keith Ortiz (Albuquerque, New Mexico); Brent T. Meyer (Albuquerque, New Mexico); Sean Yen (Albuquerque, New Mexico); Gilbert V. Herrera (Columbia, Maryland); Anthony L. Lentine (Albuquerque, New Mexico); Gwendolyn Hummel (Albuquerque, New Mexico); Robin B. Jacobs-Gedrim (Albuquerque, New Mexico) |
| ABSTRACT | A maze-based switch generally having three functional blocks is disclosed. The first functional block handles communications by accepting an entered maze pattern from an external system controller and outputting the entered maze pattern (and optionally its directional complement) to the second functional block. The second functional block stores the maze pattern (and optionally its directional complement) to a permanent storage element and outputs the stored, entered maze pattern and its directional complement to a series of transistors in the third functional block. The third functional block is an electronic maze in which a correct maze pattern and its directional complement must be received by the transistors for the transistors to pass electrical power through the electronic maze to a connected element. The third functional block may alternatively be implemented with optical elements, optoelectronic elements, microelectromechanical elements, or elements formed by other microsystem technologies. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/532108 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 5/266 (20130101) Optical Elements, Systems, or Apparatus G02B 6/29355 (20130101) Selecting H04Q 11/0005 (20130101) Original (OR) Class H04Q 2011/0035 (20130101) H04Q 2011/0041 (20130101) H04Q 2011/0058 (20130101) H04Q 2213/13003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12063788 | Dowben et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | NUTECH VENTURES (Lincoln, Nebraska); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Peter A. Dowben (Crete, Nebraska); Ruihua Cheng (Indianapolis, Indiana); Xiaoshan Xu (Lincoln, Nebraska); Alpha T. N'Diaye (Berkeley, California); Aaron Mosey (Indianapolis, Indiana); Guanhua Hao (Lincoln, Nebraska); Thilini K. Ekanayaka (Lincoln, Nebraska); Xuanyuan Jiang (Gainesville, Florida); Andrew J. Yost (Stillwater, Oklahoma); Andrew Marshall (Dallas, Texas); Azad J. Naeemi (Atlanta, Georgia) |
| ABSTRACT | A thin film molecular memory is provided that satisfies criteria needed to make a molecular spintronic device, based on spin crossover complexes, competitive with silicon technology. These criteria include, device implementation, a low coercive voltage (less than 1V) and low write peak currents (on the order of 104 A/cm2), a device on/off ratio >10, thin film quality, the ability to “lock” the spin state (providing nonvolatility), the ability to isothermally “unlock” and switch the spin state with voltage, conductance change with spin state, room temperature and above room temperature operation, an on-state device resistivity less than 1 Ω·cm, a device fast switching speed (less than 100 ps), device endurance (on the order of 1016 switches without degradation), and the ability of having a device with a transistor channel width of 10 nm or below. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/583858 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/5607 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/516 (20130101) H01L 29/78391 (20140902) Electronic Memory Devices H10B 51/30 (20230201) Original (OR) Class H10B 61/10 (20230201) H10B 61/22 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12059000 | Marenda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Daniel R. Marenda (Elkins Park, Pennsylvania); Sean O'Donnell (Swarthmore, Pennsylvania) |
| ABSTRACT | The disclosure provides a human-safe method of killing or controlling insects using a non-toxic composition comprising erythritol ((2R,3S)-butane-1,2,3,4-tetraol). The disclosure also provides non-toxic compositions comprising erythritol suitable for killing insects in residential, commercial, and agricultural locales. |
| FILED | Thursday, October 20, 2022 |
| APPL NO | 17/970184 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/006 (20130101) A01N 25/10 (20130101) A01N 25/30 (20130101) A01N 31/02 (20130101) Original (OR) Class Biocidal, Pest Repellant, Pest Attractant or Plant Growth Regulatory Activity of Chemical Compounds or Preparations A01P 7/04 (20210801) A01P 19/00 (20210801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059251 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Qiao Lin (New York, New York); Yibo Zhu (New York, New York); Junyi Shang (New York, New York); Zhixing Zhang (New York, New York); Xuejun Wang (New York, New York); Jaeyoung Yang (New York, New York); Cheng Wang (New York, New York); Zhuang Hao (New York, New York) |
| ABSTRACT | A microdevice for monitoring a target analyte is provided. The microdevice can include a field effect transistor comprising a substrate, a gate electrode, and a microfluidic channel including graphene. The microfluidic channel can be formed between drain electrodes and source electrodes on the substrate. The microdevice can also include at least one aptamer functionalized on a surface of the graphene. The at least one aptamer can be adapted for binding to the target analyte. Binding of the target analyte to the at least one aptamer can alter the conductance of the graphene. |
| FILED | Thursday, March 05, 2020 |
| APPL NO | 16/810183 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1477 (20130101) A61B 5/1491 (20130101) A61B 5/6821 (20130101) A61B 5/14507 (20130101) A61B 5/14532 (20130101) Original (OR) Class A61B 5/14539 (20130101) A61B 5/14546 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4145 (20130101) G01N 27/4146 (20130101) G01N 33/74 (20130101) G01N 2333/62 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0262 (20130101) H01L 21/02425 (20130101) H01L 21/02527 (20130101) H01L 21/02664 (20130101) H01L 23/38 (20130101) H01L 29/1606 (20130101) Organic electric solid-state devices H10K 10/484 (20230201) H10K 85/20 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12059830 | Baer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Eric Baer (Cleveland Heights, Ohio); Andy Olah (Spencer, Ohio); Zhenpeng Li (Shaker Heights, Ohio); Michael Hore (Shaker Heights, Ohio); Cong Zhang (Cleveland, Ohio) |
| ABSTRACT | A security marking has a physically unclonable function (PUF) wherein the PUF includes a disordered multilayer photonic crystal structure having an electromagnetic transmission and/or reflection spectrum and/or spectra upon receipt of electromagnetic radiation within a photonic bandgap region of the structure that is unique to the structure. |
| FILED | Monday, June 06, 2022 |
| APPL NO | 17/832892 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/001 (20190201) Original (OR) Class B29C 48/08 (20190201) B29C 48/21 (20190201) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/0032 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2007/008 (20130101) Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/21 (20141001) B42D 25/45 (20141001) B42D 25/324 (20141001) B42D 25/328 (20141001) B42D 25/378 (20141001) B42D 25/382 (20141001) B42D 25/387 (20141001) Optical Elements, Systems, or Apparatus G02B 1/04 (20130101) G02B 5/1814 (20130101) G02B 2005/1804 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060318 | Lu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Zheng-Rong Lu (Cleveland, Ohio); Da Sun (Cleveland, Ohio); Rebecca Schur (Cleveland, Ohio) |
| ABSTRACT | A nanosized complex includes a nucleic acid and a compound comprising formula (I): wherein R1 is an alkylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted alkyl group, an alkenyl group, an acyl group, or an aromatic group, or a polymer, a targeting group, a detectable moiety, or a linker, or a combination thereof, and at least one of R4 and R5 includes a retinoid or retinoid derivative that targets and/or binds to an interphotoreceptor retinoid binding protein; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof. |
| FILED | Thursday, July 30, 2020 |
| APPL NO | 16/943008 |
| ART UNIT | 1699 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Acyclic or Carbocyclic Compounds C07C 403/10 (20130101) Original (OR) Class C07C 403/12 (20130101) C07C 403/14 (20130101) C07C 403/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060398 | Sourlis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Arjirios Sourlis (Zurich, Switzerland); Anna Duraj-Thatte (Kensington, California); Avinash Manjula Basavanna (Allston, Massachusetts); Neel Satish Joshi (Somerville, Massachusetts) |
| ABSTRACT | Disclosed herein are engineered bacteria that manufacture biofilms from bacterial amyloid structures. These biofilms and biofilm matrices are capable of generating fibrous proteinaceous networks and being used as 3D-printing inks. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 17/254019 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/32 (20130101) A61L 15/42 (20130101) A61L 24/0031 (20130101) A61L 24/108 (20130101) A61L 27/52 (20130101) A61L 27/227 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Peptides C07K 14/75 (20130101) C07K 14/78 (20130101) C07K 14/4711 (20130101) Original (OR) Class C07K 2319/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060513 | Jákli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Antal Jákli (Kent, Ohio); W. S. Kelum Perera (Kent, Ohio) |
| ASSIGNEE(S) | KENT STATE UNIVERSITY (Kent, Ohio) |
| INVENTOR(S) | Antal Jákli (Kent, Ohio); W. S. Kelum Perera (Kent, Ohio) |
| ABSTRACT | The present invention relates to polymer stabilized nematic liquid crystal microlenses. The microlenses can be made from a nematic liquid crystal, a chiral dopant, a reactive monomer, and a photoinitiator. The microlenses can be prepared by spin coating a liquid crystal mixture onto an array including a nickel transmission electron microscope grid. The focal length of the microlens array can be tuned electrically. |
| FILED | Thursday, December 01, 2022 |
| APPL NO | 18/073073 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/14 (20130101) C09K 19/025 (20130101) Original (OR) Class C09K 19/586 (20130101) C09K 19/2021 (20130101) C09K 2019/122 (20130101) C09K 2019/0407 (20130101) C09K 2019/2035 (20130101) C09K 2323/061 (20200801) Optical Elements, Systems, or Apparatus G02B 3/14 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0027 (20130101) G02F 1/141 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060515 | Jakli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Antal Jakli (Kent, Ohio); Chenrun Feng (Kent, Ohio) |
| ASSIGNEE(S) | KENT STATE UNIVERSITY (Kent, Ohio) |
| INVENTOR(S) | Antal Jakli (Kent, Ohio); Chenrun Feng (Kent, Ohio) |
| ABSTRACT | A doped ferroelectric nematic liquid crystal includes a chirality-induced stabilization of the polar nematic order, improved relaxation time for electro-optical switching, and selective reflection in the visible wavelength that is reversibly tunable. The ferroelectric nematic liquid crystal is doped with a chiral dopant selected from benzoic acid, 4-hexyl-,4-[[(1-methylheptyl)oxy]carbonyl]phenyl ester (ZLI811) and BDH1281. |
| FILED | Wednesday, September 21, 2022 |
| APPL NO | 17/949516 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 19/025 (20130101) C09K 19/0225 (20130101) C09K 19/584 (20130101) Original (OR) Class C09K 2019/2078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060598 | Pfleger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Brian F. Pfleger (Madison, Wisconsin); Nestor Hernandez-Lozada (Jena, Germany); Rung-Yi Lai (Changhua, Taiwan) |
| ABSTRACT | Mutant thioesterases having enhanced medium chain substrate activity, polynucleotides encoding and configured to express the mutant thioesterases in a transformed host cell, host cells transformed to contain the polynucleotides, and methods of using same. |
| FILED | Tuesday, July 05, 2022 |
| APPL NO | 17/857624 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 15/52 (20130101) C12N 15/70 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/6409 (20130101) Original (OR) Class Enzymes C12Y 301/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061102 | Hallstrom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (Boca Raton, Florida) |
| ASSIGNEE(S) | FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (Boca Raton, Florida) |
| INVENTOR(S) | Jason O. Hallstrom (Boca Raton, Florida); Jiannan Zhai (Boca Raton, Florida); Chancey Kelley (Lake Worth, Florida); Michael Brown (San Antonio, Texas); Andrew Van Zwieten (Huntington Beach, California); Don Salamon (Piney Point, Maryland) |
| ABSTRACT | Systems and methods for operating a fluid supply system. The methods comprise: using a micro-turbine and an Energy Harvesting Circuit (“EHC”) to harvest energy from a fluid flowing through a pipeline; operating a switch to disconnect the EHC from the micro-turbine when an amount of energy harvested reaches a threshold value; detecting by a sensor device an amount of natural fluid flow through the pipeline while the EHC is disconnected from the micro-turbine; and operating the switch to reconnect the EHC to the micro-turbine after the amount of natural fluid flow has been detected. |
| FILED | Thursday, June 01, 2017 |
| APPL NO | 16/610331 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 25/00 (20130101) A01G 25/16 (20130101) Machines or Engines for Liquids F03B 13/10 (20130101) Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/075 (20130101) Original (OR) Class G01F 15/0755 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 3/2807 (20130101) Dynamo-electric Machines H02K 7/1823 (20130101) H02K 11/26 (20160101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061165 | Thomas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Jayan Thomas (Orlando, Florida); Jinxin Li (Orlando, Florida); Foram Madiyar (Port Orange, Florida) |
| ABSTRACT | One type of plasmonic organic electrochemical transistor (POECT) includes a channel comprising an organic semiconductor, a gate electrode comprising at least one of: an ensemble of nanoparticles and an array of nanostructures, wherein each of the at least one of: an ensemble of nanoparticles and an array of nanostructures comprises localized plasmonic material, an analyte formed at least one of: (a) over the at least one of: the ensemble of nanoparticles and the array of nanostructures and (b) around the at least one of: the ensemble of nanoparticles and the array of nanostructures, wherein an electrolyte is configured to be formed at least one of: between the channel and the gate electrode and over the channel and the gate electrode, a source electrode electrically connected to a first end of the channel; and a drain electrode electrically connected to a second end of the channel which is opposite the first end. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/532141 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/4146 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061287 | Stillwell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY CORPORATION FOR ATMOSPHERIC RESEARCH (Boulder, Colorado); MONTANA STATE UNIVERSITY (Bozeman, Montana) |
| ASSIGNEE(S) | University Corporation for Atmospheric Research (Boulder, Colorado); Montana State University (Bozeman, Montana) |
| INVENTOR(S) | Robert Stillwell (Broomfield, Colorado); Scott Spuler (Westminster, Colorado); Matthew Hayman (Boulder, Colorado); Kevin S. Repasky (Bozeman, Montana) |
| ABSTRACT | A beam transmitter, a receiver, and a LIDAR, along with methods to operate each are provided. The beam transmitter comprises a first and a second transmission channel (201a, 201b), each transmission channel including a first online laser, a first offline laser, and a first laser transmission selection switch operable to toggle between including the first online laser signal and the first offline laser signal in a first transmission beam. The beam transmitter further includes at least one light redirection device operable to coalign the first transmission beam with the second transmission beam. The receiver comprises a first splitter (402a, 402b), a first filter (404a, 404b), a first detector channel (406a, 406b), a second splitter (408a, 408b), a second filter (410a, 410b), and a second detector channel (412a, 412b). The LIDAR includes the beam transmitter, the receiver, and a shared telescope. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 17/294673 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) G01S 7/4815 (20130101) Original (OR) Class G01S 17/86 (20200101) G01S 17/95 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061407 | Yi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Ya Sha Yi (Troy, Michigan); Da Chuan Wu (Ann Arbor, Michigan) |
| ABSTRACT | Beam steering device such as optical phased array (OPA) is a key component in applications of solid-state LIDAR and wireless communication. The traditional single-layer OPA results in a significant energy loss due to the substrate leakage caused by the downward coupling from the grating coupler structure. In the present disclosure, we have investigated a structure based on multi-layers Si3N4/SiO2 platform that can form a 3D OPA to emit the light from the edge of the device with a high efficiency, a 2D converged out-coupling beam will be end-fired to the air. The high efficiency and wide horizontal beam steering are demonstrated numerically, the influence of vertical crosstalk, the delay length, number of waveguide layers, and the fabrication feasibility are also discussed. |
| FILED | Tuesday, March 02, 2021 |
| APPL NO | 17/189472 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4814 (20130101) G01S 7/4817 (20130101) G01S 7/4818 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/291 (20210101) G02F 1/292 (20130101) Original (OR) Class G02F 1/2955 (20130101) G02F 2201/20 (20130101) G02F 2203/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12061790 | Krishnamurthy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Vinayak Raman Krishnamurthy (West Lafayette, Indiana); Cecil Piya (West Lafayette, Indiana); Karthik Ramani (West Lafayette, Indiana) |
| ABSTRACT | Some examples provides a set of frameworks, process and methods aimed at enabling the expression and exploration of free-form and parametric 3D shape designs enabled through natural interactions with a hand-held mobile device acting as a controller for 3D virtual objects. A reference plane in a virtual space generated by the location of the mobile device may be used to select a 3D virtual object intersected by the reference plane. Positioning of the mobile device may also be used to control a pointer in the virtual space. In an example, the orientation of the mobile device may be detected by an accelerometer or gyroscope. In example, the position of the mobile device may be detected by a position sensor. |
| FILED | Friday, June 23, 2023 |
| APPL NO | 18/340351 |
| ART UNIT | 2622 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 3/017 (20130101) G06F 3/0346 (20130101) G06F 3/04845 (20130101) G06F 3/04883 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 19/006 (20130101) G06T 19/20 (20130101) G06T 2219/2016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062177 | Atria et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | nView medical Inc. (Salt Lake City, Utah) |
| ASSIGNEE(S) | nView medical Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | Cristian Atria (Salt Lake City, Utah); Arvidas B. Cheryauka (Salt Lake City, Utah); Lisa M. Last (Salt Lake City, Utah) |
| ABSTRACT | Imaging systems comprising x-ray image reconstruction systems combined with optical imaging and/or tracking systems. In some embodiments, the imaging system may comprise an x-ray image reconstruction system configured to generate three-dimensional image data of at least an internal portion of a target object under a surface of the target object and a three-dimensional optical imaging system configured to reconstruct an image of at least a portion of the surface of the target object by generating surface three-dimensional image data. The three-dimensional optical imaging system may be registered to the x-ray tomosynthesis image reconstruction system such that three-dimensional image data from the x-ray tomosynthesis image reconstruction system and three-dimensional image data from the three-dimensional optical imaging system may be used as a constraint to improve image quality of an image of the target object. |
| FILED | Friday, November 20, 2020 |
| APPL NO | 17/100097 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) Original (OR) Class G06T 11/006 (20130101) G06T 2200/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062436 | Ning et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio); The Trustees of Indiana University (Bloomington, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corp. (Bloomington, Indiana); Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Xia Ning (Columbus, Ohio); Zhiyun Ren (Sunnyvale, California); Bo Peng (Columbus, Ohio); Titus K. Schleyer (Indianapolis, Indiana) |
| ABSTRACT | Disclosed embodiments include computer-implemented methods and systems that can efficiently generate highly relevant recommended search terms to clinicians. A hybrid collaborative filtering model recommends search terms for a specific patient to the clinician. The model draws on information from patients' clinical encounters and the searches that were performed during the clinical encounters. To generate recommendations, the model uses search terms which are (1) frequently co-occurring with the ICD codes recorded for the patient and (2) highly relevant to the most recent search terms. One variation of the model uses only the most recent ICD codes assigned to the patient. Another variation uses all ICD codes. Comprehensive experiments of embodiments of the methods and systems have demonstrate high levels of performance. |
| FILED | Monday, November 15, 2021 |
| APPL NO | 17/526591 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Electric Digital Data Processing G06F 16/24578 (20190101) G06F 17/16 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/20 (20180101) Original (OR) Class G16H 70/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062926 | Babakhani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Aydin Babakhani (Los Angeles, California); Hamed Rahmani (Belle Mead, New Jersey); Hidemasa Mitsui (Santa Clara, California) |
| ABSTRACT | Systems and methods for utilizing a small form-factor, wirelessly powered transceiver are disclosed. In one embodiment, a wireless powered transceiver includes a receive antenna configured to receive a receive signal, a transmit antenna configured to transmit a transmit signal, a power harvesting system including a rectifier circuit configured convert radio frequency energy from the receive signal into DC (direct current) voltage, and a power management unit (PMU) configured to set the operating mode and biasing condition of the receive and transmit circuitry blocks and provide DC voltage from the receive circuitry block to the transmit circuitry block to maintain a minimum voltage, a receiver circuitry block configured to provide energy from the receive signal to the power harvesting system, and a transmitter circuitry block including a data modulator circuit, the data modulator circuit configured to generate the transmit signal using DC voltage received from the power management unit. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/929959 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/001 (20200101) H02J 50/27 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12063788 | Dowben et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | NUTECH VENTURES (Lincoln, Nebraska); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia); THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana); BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Peter A. Dowben (Crete, Nebraska); Ruihua Cheng (Indianapolis, Indiana); Xiaoshan Xu (Lincoln, Nebraska); Alpha T. N'Diaye (Berkeley, California); Aaron Mosey (Indianapolis, Indiana); Guanhua Hao (Lincoln, Nebraska); Thilini K. Ekanayaka (Lincoln, Nebraska); Xuanyuan Jiang (Gainesville, Florida); Andrew J. Yost (Stillwater, Oklahoma); Andrew Marshall (Dallas, Texas); Azad J. Naeemi (Atlanta, Georgia) |
| ABSTRACT | A thin film molecular memory is provided that satisfies criteria needed to make a molecular spintronic device, based on spin crossover complexes, competitive with silicon technology. These criteria include, device implementation, a low coercive voltage (less than 1V) and low write peak currents (on the order of 104 A/cm2), a device on/off ratio >10, thin film quality, the ability to “lock” the spin state (providing nonvolatility), the ability to isothermally “unlock” and switch the spin state with voltage, conductance change with spin state, room temperature and above room temperature operation, an on-state device resistivity less than 1 Ω·cm, a device fast switching speed (less than 100 ps), device endurance (on the order of 1016 switches without degradation), and the ability of having a device with a transistor channel width of 10 nm or below. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/583858 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/5607 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/516 (20130101) H01L 29/78391 (20140902) Electronic Memory Devices H10B 51/30 (20230201) Original (OR) Class H10B 61/10 (20230201) H10B 61/22 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 12060290 | Cumbie |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PANCOPIA, INC (Hampton, Virginia) |
| ASSIGNEE(S) | PANCOPIA, INC (Hampton, Virginia) |
| INVENTOR(S) | William E Cumbie (Newport News, Virginia) |
| ABSTRACT | A method and system to significantly reduce odor emissions caused by ammonia and other noxious gasses and reduce nitrogen levels in animal husbandry wastewater effectively and efficiently by the use of flush water that has been biochemically conditioned to lower the pH thus reducing the level of un-ionized compounds including NH3 which can volatilize into the atmosphere and which method and system can also be used to remove ammonia and nitrogen from the wastewater system. The present disclosure includes the use of flush water that has been biochemically conditioned to lower its pH thus sequestering non-ionized ammonia from being released from a liquid as ammonia gas. This disclosure relates to the new use of nitrification for biochemical conditioning of wastewater for use as flush water to reduce atmospheric ammonia emissions. |
| FILED | Monday, September 21, 2020 |
| APPL NO | 17/027343 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Planting; Sowing; Fertilising A01C 3/023 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/5281 (20130101) C02F 3/006 (20130101) C02F 3/303 (20130101) Original (OR) Class C02F 2001/007 (20130101) C02F 2101/16 (20130101) C02F 2103/20 (20130101) C02F 2209/06 (20130101) C02F 2303/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060403 | Rowland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| ASSIGNEE(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| INVENTOR(S) | Raymond R. R. Rowland (Manhattan, Kansas); Ana Stoian (Manhattan, Kansas) |
| ABSTRACT | The present disclosure provides compositions and methods for decreasing permissiveness to infection by PRRSV. The methods involve inserting peptides or oligopeptides into the CD163 SRCR domain 5 to disrupt the protein structure and thereby prevent PRRSV infection. The deletion of the exon 13 region of PSTII eliminates infection. The replacement of cysteine residues with alanines in SRCR5 as a means to disrupt disulfide bond formation. The final method is the deletion of, or amino acid substitution within the SRCR4-5 interdomain region. |
| FILED | Tuesday, October 16, 2018 |
| APPL NO | 16/756756 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/027 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060565 | Callahan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by The Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Ann M. Callahan (Shepherdstown, West Virginia); Christopher D. Dardick (Charles Town, West Virginia) |
| ABSTRACT | The disclosure relates to polynucleotides comprising an endocarp-specific promoter sequence from the peach peroxidase (POX) gene operably linked to a heterologous nucleotide sequence encoding a product of interest. The polynucleotides can be used to specifically alter endosperm gene expression in fruit. In a transgenic cell, the polynucleotides may block formation of phenylpropanoid pathway lignin-pathway precursors, formation of lignin monomers, and/or polymerization of lignin monomers. |
| FILED | Wednesday, March 15, 2023 |
| APPL NO | 18/184404 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8234 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12060679 | Tisserat et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bradley University (Peoria, Illinois); The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | Bradley University (Peoria, Illinois) |
| INVENTOR(S) | Brent Tisserat (Washington, Illinois); Luke Haverhals (Peoria, Illinois); Zengshe Liu (Morton, Illinois) |
| ABSTRACT | Unique, inexpensive, and. strong biocomposites are obtained from blending cellulose matrix materials pith lignocellulosic reinforcement materials with the aid of alkaline aqueous solvent and cold temperatures. These lignocellulosic composites (LCs) are produced without use of any thermoplastic resins, adhesives, catalysts, plasticizers or d chemical or physical procedures. The LCs include a matrix and a reinforcement material. The matrix is a cellulose material (e.g., cotton, hemp, flax, or wood) that is liquefied using an aqueous alkaline solvent solution under cold temperatures to more readily adhere and or incorporate/encapsulate the lignocellulosic reinforcements (wood chips, fibers, and other lignocellulosic sources). |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/212345 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 97/02 (20130101) C08L 2201/06 (20130101) Production of Cellulose by Removing Non-cellulose Substances From Cellulose-containing Materials; Regeneration of Pulping Liquors; Apparatus Therefor D21C 3/02 (20130101) D21C 3/20 (20130101) D21C 3/022 (20130101) Original (OR) Class D21C 3/22 (20130101) D21C 5/00 (20130101) D21C 5/022 (20130101) Pulp Compositions; Preparation Thereof Not Covered by Subclasses D21C or D21D; Impregnating or Coating of Paper; Treatment of Finished Paper Not Covered by Class B31 or Subclass D21G; Paper Not Otherwise Provided for D21H 11/12 (20130101) D21H 11/14 (20130101) D21H 21/18 (20130101) D21H 21/34 (20130101) D21H 21/36 (20130101) Fibreboard; Manufacture of Articles From Cellulosic Fibrous Suspensions or From Papier-mache D21J 3/00 (20130101) D21J 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 12060290 | Cumbie |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PANCOPIA, INC (Hampton, Virginia) |
| ASSIGNEE(S) | PANCOPIA, INC (Hampton, Virginia) |
| INVENTOR(S) | William E Cumbie (Newport News, Virginia) |
| ABSTRACT | A method and system to significantly reduce odor emissions caused by ammonia and other noxious gasses and reduce nitrogen levels in animal husbandry wastewater effectively and efficiently by the use of flush water that has been biochemically conditioned to lower the pH thus reducing the level of un-ionized compounds including NH3 which can volatilize into the atmosphere and which method and system can also be used to remove ammonia and nitrogen from the wastewater system. The present disclosure includes the use of flush water that has been biochemically conditioned to lower its pH thus sequestering non-ionized ammonia from being released from a liquid as ammonia gas. This disclosure relates to the new use of nitrification for biochemical conditioning of wastewater for use as flush water to reduce atmospheric ammonia emissions. |
| FILED | Monday, September 21, 2020 |
| APPL NO | 17/027343 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Planting; Sowing; Fertilising A01C 3/023 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/5281 (20130101) C02F 3/006 (20130101) C02F 3/303 (20130101) Original (OR) Class C02F 2001/007 (20130101) C02F 2101/16 (20130101) C02F 2103/20 (20130101) C02F 2209/06 (20130101) C02F 2303/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12062177 | Atria et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | nView medical Inc. (Salt Lake City, Utah) |
| ASSIGNEE(S) | nView medical Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | Cristian Atria (Salt Lake City, Utah); Arvidas B. Cheryauka (Salt Lake City, Utah); Lisa M. Last (Salt Lake City, Utah) |
| ABSTRACT | Imaging systems comprising x-ray image reconstruction systems combined with optical imaging and/or tracking systems. In some embodiments, the imaging system may comprise an x-ray image reconstruction system configured to generate three-dimensional image data of at least an internal portion of a target object under a surface of the target object and a three-dimensional optical imaging system configured to reconstruct an image of at least a portion of the surface of the target object by generating surface three-dimensional image data. The three-dimensional optical imaging system may be registered to the x-ray tomosynthesis image reconstruction system such that three-dimensional image data from the x-ray tomosynthesis image reconstruction system and three-dimensional image data from the three-dimensional optical imaging system may be used as a constraint to improve image quality of an image of the target object. |
| FILED | Friday, November 20, 2020 |
| APPL NO | 17/100097 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) Original (OR) Class G06T 11/006 (20130101) G06T 2200/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 12062228 | Fry |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Mark Fry (Marco Island, Florida) |
| ABSTRACT | Systems and methods of detecting a vortex made by a travelling object is disclosed. In some configurations, a graphic recognition algorithm and vortex similarity engine are used to determine whether a visual media file captured by a media collector contains a vortex. The vortex similarity engine may be configured to determine or identify certain properties about the travelling object based on the travelling object vortex. In some configurations, a computer may trigger an alert if a travelling object vortex is not expected to be in the visual media file. |
| FILED | Thursday, November 02, 2023 |
| APPL NO | 18/386410 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/761 (20220101) G06V 10/776 (20220101) Original (OR) Class G06V 20/52 (20220101) G06V 2201/08 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 12061217 | Vabnick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Federal Bureau of Investigation (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Federal Bureau of Investigation, Department of Justice (Washington, District of Columbia) |
| INVENTOR(S) | Ian B. Vabnick (Fredericksburg, Virginia); Michael Malone (Quantico, Virginia) |
| ABSTRACT | Circuit test devices and methods are provided. The method includes measuring a voltage between first and second conductor points (CPs) of a circuit under test (CUT), and determining if the measured voltage is less than a low voltage threshold value (LVTV) indicative of electrical continuity (EC) between the first and second CPs. In response to determining that the measured voltage is less than the LVTV, the method includes: transmitting a test signal (TS) to the first or second CP, and determining if the test signal is received after being transmitted. In response to determining that the TS is received, a presence of EC between the first and second conductor points is reported, and in response to determining that the TS is not received, absence of EC between the first and second CPs, or a lack of electrical contact between the VMC and the first and/or second CP(s), is reported. |
| FILED | Tuesday, November 29, 2022 |
| APPL NO | 18/071415 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/16504 (20130101) Original (OR) Class G01R 19/16528 (20130101) G01R 31/54 (20200101) G01R 31/58 (20200101) G01R 31/3277 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 12062375 | Wei |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Yuan-Jun Wei (Broadlands, Virginia) |
| ABSTRACT | Disclosed herein are systems and methods for processing an audio file to perform audio Segmentation and Speaker Role Identification (SRID) by training low level classifier and high level clustering components to separate and identify audio from different sources in an audio file by unifying audio separation and automatic speech recognition (ASR) techniques in a single system. Segmentation and SRID can include separating audio in an audio file into one or more segments, based on a determination of the identity of the speaker, category of the speaker, or source of audio in the segment. In one or more examples, the disclosed systems and methods use machine learning and artificial intelligence technology to determine the source of segments of audio using a combination of acoustic and language information. In some examples, the acoustic and language information is used to classify audio in each frame and cluster the audio into segments. |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 17/545710 |
| ART UNIT | 2659 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/18 (20130101) G10L 15/063 (20130101) G10L 17/18 (20130101) Original (OR) Class G10L 2015/0631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 12060396 | Pozzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee); The United States as Represented by The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee); The United States as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Ambra A. Pozzi (Nashville, Tennessee); Manuel Chiusa (Nashville, Tennessee); Jack J. Hawiger (Nashville, Tennessee); Jozef Zienkiewicz (Nashville, Tennessee) |
| ABSTRACT | Disclosed herein are compositions and methods for inhibiting collagen production mediated by the Fused in Sarcoma (FUS) ribonucleoprotein. As disclosed herein, the C terminal domain of FUS contains an uncommon nuclear localization sequence (NLS) motif called PY-NLS that binds the nuclear import receptor transportin. Phosphorylation of FUS leads to its association with transportin and nuclear translocation with consequent increased in collagen production. Therefore, disclosed herein is an isolated peptide having a transportin-binding moiety, which inhibits FUS from binding transportin, linked to a membrane translocating motif. These compositions and methods can be used to inhibit FUS-mediated collagen production, and treat fibrotic disease involving FUS-mediated collagen accumulation in kidneys and other organs displaying fibrotic diseases. |
| FILED | Monday, January 29, 2018 |
| APPL NO | 16/481128 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 38/1777 (20130101) A61K 38/1825 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) Peptides C07K 14/50 (20130101) C07K 14/4703 (20130101) Original (OR) Class C07K 14/70557 (20130101) C07K 2319/02 (20130101) C07K 2319/10 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12062297 | Buras et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TIENOVIX, LLC (Houston, Texas) |
| ASSIGNEE(S) | Tienovix, LLC (Houston, Texas) |
| INVENTOR(S) | William R. Buras (Friendswood, Texas); Craig S. Russell (League City, Texas); Kyle Q. Nguyen (League City, Texas) |
| ABSTRACT | Methods for providing real-time, three-dimensional (3D) augmented reality (AR) feedback guidance to a user of an equipment system for training or improved performance, including comparing sensed, real-time user positioning data and data received from the equipment system during use to reference positioning and procedure outcome data, and generating and providing to a user real-time position-based and outcome-based 3D AR feedback based on comparing the sensed and reference data. |
| FILED | Wednesday, May 17, 2023 |
| APPL NO | 18/318769 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/06 (20130101) A61B 8/52 (20130101) A61B 8/085 (20130101) A61B 8/466 (20130101) A61B 8/467 (20130101) A61B 8/4245 (20130101) A61B 8/4254 (20130101) A61B 8/4263 (20130101) A61B 34/20 (20160201) A61B 90/361 (20160201) A61B 2034/2048 (20160201) A61B 2034/2055 (20160201) A61B 2090/365 (20160201) A61B 2090/378 (20160201) A61B 2090/3945 (20160201) A61B 2562/0219 (20130101) Optical Elements, Systems, or Apparatus G02B 27/017 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/016 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/065 (20130101) G09B 23/286 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 40/63 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 12060868 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Na Li (Richardson, Texas); Carter S. Haines (Murphy, Texas); Marcio D. Lima (Richardson, Texas); Monica Jung DeAndrade (Richardson, Texas); Shaoli Fang (Richardson, Texas); Jiyoung Oh (Richardson, Texas); Mikhail E. Kozlov (Dallas, Texas); Dongseok Suh (Plano, Texas); Ray H. Baughman (Dallas, Texas) |
| ABSTRACT | Actuators (artificial muscles) comprising twisted polymer fibers generate tensile actuation when powered thermally. In some embodiments, the thermally-powered polymer fiber tensile actuator can be incorporated into an article, such as a textile or garment. |
| FILED | Monday, October 18, 2021 |
| APPL NO | 17/504305 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/00 (20130101) Spinning or Twisting D01H 1/10 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/02 (20130101) D02G 3/26 (20130101) D02G 3/448 (20130101) Braiding or Manufacture of Lace, Including Bobbin-net or Carbonised Lace; Braiding Machines; Braid; Lace D04C 1/02 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/046 (20130101) D10B 2401/061 (20130101) D10B 2509/00 (20130101) Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/06 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 10/00 (20130101) H02N 11/006 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2925 (20150115) Y10T 428/249921 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 12062008 | Turner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Alison Frankowski Turner (Arlington, Virginia); Marc D. McCrery (Arlington, Virginia); James J. Boldt (Leesburg, Virginia) |
| ABSTRACT | Methods and systems for coordinating item delivery are disclosed. In one aspect, a method comprises receiving delivery route data from a carrier device, generating, based on the delivery route data, a digital route for a delivery resource, the digital route comprising a street portion and an office portion, wherein the street portion comprises: a plurality of delivery points at which the carrier is to perform a service, and a segmented travel course for the carrier to travel to each of the plurality of delivery points in a determined sequence, and wherein the office portion comprises details regarding one or more office activities performed by the carrier to prepare for or conclude the street portion of a delivery route. The method further comprises determining an expected duration of time for: (1) travel of each segment of the travel course, (2) completion of each of the street activities, and (3) completion of the one or more office activities. |
| FILED | Thursday, April 16, 2020 |
| APPL NO | 16/850970 |
| ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0838 (20130101) G06Q 10/08355 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
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How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, August 13, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240813.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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