FedInvent™ Patents
Patent Details for Tuesday, August 27, 2024
This page was updated on Tuesday, September 03, 2024 at 09:07 PM GMT
Department of Health and Human Services (HHS)
| US 12070241 | Franco et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Walfre Franco (Westborough, Massachusetts); Esmeralda Ibarra-Silva (Boston, Massachusetts); William A. Farinelli (Boston, Massachusetts); Joshua Tam (Boston, Massachusetts); R. Rox Anderson (Boston, Massachusetts); Lynn Drake (Boston, Massachusetts) |
| ABSTRACT | Systems and methods are provided for performing a hair transplant using a hair transplant device. The hair transplant device comprises a coring needle, a splitting needle, a housing, and a user interface. The coring needle forms a coring lumen configured to extract a hair follicle from a donor site. The splitting needle is configured to create an opening in a recipient site. The housing at least partially surrounds one of the coring needle and the splitting needle. The user interface extends from the housing and is movable relative to the coring needle to push the hair follicle from the coring lumen into the opening in the recipient site formed by the splitting needle. |
| FILED | Monday, July 16, 2018 |
| APPL NO | 16/629657 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/32053 (20130101) Original (OR) Class A61B 2017/00367 (20130101) A61B 2017/00752 (20130101) A61B 2017/00969 (20130101) A61B 2017/3454 (20130101) A61B 2017/320064 (20130101) A61B 2090/034 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070318 | Frankel et al. |
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| FUNDED BY |
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| APPLICANT(S) | Epitel, Inc. (Salt Lake City, Utah) |
| ASSIGNEE(S) | Epitel, Inc. (Salt Lake City, Utah) |
| INVENTOR(S) | Mitchell A. Frankel (Salt Lake City, Utah); Robert Lingstuyl (Salt Lake City, Utah); Michael K. Elwood (Farmington, Utah) |
| ABSTRACT | Provided herein are systems, kits, and methods for monitoring brain activity. In some implementations, a system includes a plurality of wearable sensors having a housing with an extended, rounded shape are removably attached to the scalp of a patient and monitor electroencephalogram (EEG) signals. Approaches for instructing a user to position and active that wearable sensors are disclosed. Approaches for facilitating collection, synchronization, and processing of EEG signals are disclosed. Approaches for handing off control of the wearable sensors between portable computing devices are disclosed. |
| FILED | Friday, December 16, 2022 |
| APPL NO | 18/067608 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/0024 (20130101) A61B 5/369 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070342 | Hull |
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| FUNDED BY |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Holly Hull (Leawood, Kansas) |
| ABSTRACT | A medical imaging support includes a substantially flat radiotransparent platform, a plurality of radiotransparent flaps, and closure mechanisms. The platform has a longitudinal direction between a top edge and a bottom edge. The plurality of sets of radiotransparent flaps have a first set of the radiotransparent flaps positioned closer to the top edge in the longitudinal direction than the second set of radiotransparent flaps, and at least one set of flaps includes a first flap and a second flap where the first flap is fixed to the platform proximate a first side edge and the second flap is fixed to the platform proximate a second side edge. The closure mechanisms are positioned on the first flap or second flap of each set of radiotransparent flaps, wherein the closure mechanism selectively fixes the first flap to the second flap of each set of radiotransparent flaps. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 17/399626 |
| ART UNIT | 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/0421 (20130101) Original (OR) Class A61B 2503/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070443 | Li et al. |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Rong Li (San Antonio, Texas); Bin Yuan (San Antonio, Texas); Tyler Curiel (San Antonio, Texas) |
| ABSTRACT | The present invention provides methods and compositions for treating or preventing breast cancer with S-equol. The method and compositions are particularly suited to treating triple-negative breast cancer. The S-equol may be administered alone or in combination with one or more cytotoxic or immunotherapeutic compound or molecule. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/372352 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) Original (OR) Class A61K 39/3955 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070444 | Li et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Rong Li (Washington, District of Columbia); Bin Yuan (Hefei, China PRC); Kate Ida Lathrop (San Antonio, Texas) |
| ABSTRACT | The present invention provides methods and compositions for modulating molecular markers, and hence treating or preventing breast cancer (e.g., triple-negative breast cancer) and melanoma with a pharmaceutically effective amount of S-equol or a pharmaceutical composition comprising S-equol. The S-equol may be administered alone or in combination with one or more cytotoxic or immunotherapeutic compound or molecule. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 17/535125 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) Original (OR) Class A61K 39/39541 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070445 | Blackwell et al. |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Helen Elizabeth Blackwell (Middleton, Wisconsin); Thomas John Polaske (Madison, Wisconsin); David Lynn (Middleton, Wisconsin); Curran Gahan (Madison, Wisconsin); Kayleigh E. Nyffeler Bucci (Madison, Wisconsin) |
| ABSTRACT | The present technology provides a system for monitoring quorum-sensing in bacteria comprising bacteria that release at least one membrane-lytic toxin when the bacteria are at a quorum-sensing density; synthetic lipid vesicles comprising an environmentally sensitive indicator, wherein the synthetic lipid vesicles release the environmentally sensitive dye in the presence of an effective amount of the membrane-lytic toxins; and a growth medium; wherein the bacteria and synthetic lipid vesicles are in contact with the growth medium. Methods using the system and compounds discovered with the system (e.g., compounds of Formulas I and II) are also disclosed. |
| FILED | Friday, August 26, 2022 |
| APPL NO | 17/896558 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/381 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070463 | Bazan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College (Baton Rouge, Louisiana); UNIVERSIDAD DE ALCALÁ (Madrid, Spain) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana); UNIVERSIDAD DE ALCALÁ (Madrid, Spain) |
| INVENTOR(S) | Nicolas G. Bazan (New Orleans, Louisiana); Alberto E. Musto (New Orleans, Louisiana); Julio Alvarez-Builla (Madrid, Spain) |
| ABSTRACT | Provided are compositions that include a platelet-activating factor antagonist, pharmaceutical compositions including the platelet-activating factor antagonist, methods of treating a modulating the proliferation of a glioma or a pathological condition resulting from patient having a glioma. |
| FILED | Friday, January 10, 2020 |
| APPL NO | 16/739350 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5377 (20130101) Original (OR) Class A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/08 (20180101) A61P 35/00 (20180101) Heterocyclic Compounds C07D 211/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070465 | Zuo et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| ASSIGNEE(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| INVENTOR(S) | Jian Zuo (Omaha, Nebraska); Jeff North (Omaha, Nebraska); Santanu Hati (Omaha, Nebraska); Marisa Laura Zallocchi (Omaha, Nebraska) |
| ABSTRACT | In one aspect, use of compounds as active agents to treat a hearing impairment and to prevent a hearing impairment, and methods of treating and/or preventing hearing impairments or disorders using the compositions are disclosed. (E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-S,6-dihydropyridin-2(1H)-one and derivatives exhibit excellent protection against antibiotic-induced hearing loss in zebrafish and mice. In one aspect, (E)-1-(3-(3,4,5-trimethoxy phenyl)acryloyl)-S,6-dihydropyridin-2(1H)-one and derivatives can be used as a therapy for the treatment and/or prevention of hearing loss. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Wednesday, September 15, 2021 |
| APPL NO | 18/031998 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/45 (20130101) A61K 31/55 (20130101) Original (OR) Class A61K 31/397 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070468 | Shawber et al. |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Carrie J. Shawber (Washington, New Jersey); June K. Wu (New York, New York); Ajit Muley (San Mateo, California) |
| ABSTRACT | Provided herein are methods and compositions for treating and preventing vascular malformations including lymphatic, venous, capillary, arteriovenous, and combinations thereof. Methods of treatment and prevention include the administration of proteasome inhibitors, omipalisib, disulfiram, and agents which target genes in the PI3K/AKT/mTOR or RAS/RAF/MAPK pathways, including but not limited to Pik3ca, Pik3r3, Tsc2, Rasa1, Map2k2, and Glmn. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 17/984734 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) Original (OR) Class A61K 31/145 (20130101) A61K 31/407 (20130101) A61K 31/501 (20130101) A61K 38/06 (20130101) A61K 38/07 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070478 | Steinmetz et al. |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Nicole F. Steinmetz (San Diego, California); Karin L. Lee (Cleveland, Ohio) |
| ABSTRACT | A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle. |
| FILED | Tuesday, February 28, 2023 |
| APPL NO | 18/115066 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 35/76 (20130101) Original (OR) Class A61K 39/12 (20130101) A61K 39/39 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2770/26011 (20130101) C12N 2770/26023 (20130101) C12N 2770/26033 (20130101) C12N 2770/26042 (20130101) C12N 2770/40023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070483 | Fisher et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Aron B. Fisher (Philadelphia, Pennsylvania); Sheldon I. Feinstein (Philadelphia, Pennsylvania) |
| ABSTRACT | In various aspects and embodiments the invention provides compositions and methods useful in the treatment of acute lung injury (ALI). |
| FILED | Thursday, August 15, 2019 |
| APPL NO | 17/269097 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) Original (OR) Class A61K 38/10 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070486 | Hawiger et al. |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Jack J. Hawiger (Nashville, Tennessee); Jozef Zienkiewicz (Nashville, Tennessee) |
| ABSTRACT | The present invention relates to compositions and methods for treating autoimmune, microbial, metabolic, neoplastic, and posttraumatic diseases mediated by inflammation in a subject. Compositions and methods including at least one importin beta-selective nuclear transport modifier (NTM) and/or at least one importin alpha-selective NTM, and/or at least one importin alpha-specific NTM, and/or at least one inhibitor of importin alpha and importin beta complex formation may be administered to a subject to modulate the transport of transcription factors, mediated by nuclear import adaptors, into the nucleus of a cell resulting in a decrease or abrogation of inflammation. |
| FILED | Tuesday, June 21, 2022 |
| APPL NO | 17/845144 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/167 (20130101) A61K 31/192 (20130101) A61K 31/192 (20130101) A61K 38/12 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 38/16 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Peptides C07K 14/47 (20130101) C07K 14/50 (20130101) C07K 14/4702 (20130101) C07K 2319/00 (20130101) C07K 2319/09 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070488 | Portman |
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| APPLICANT(S) | Seattle Children's Hospital (Seattle, Washington) |
| ASSIGNEE(S) | Seattle Children's Hospital (Seattle, Washington) |
| INVENTOR(S) | Michael A. Portman (Seattle, Washington) |
| ABSTRACT | The present invention relates to the discovery that etanercept reduces the rate of resistance to intravenous gamma globulin (IVIG) in subjects with acute Kawasaki disease (KD). In certain embodiments, the co-administration of etanercept and IVIG more effectively treats acute KD in subjects older than 12 months than IVIG alone. In other embodiments, the co-administration of etanercept and IVIG ameliorates coronary artery dilation in high risk subjects. |
| FILED | Tuesday, January 18, 2022 |
| APPL NO | 17/648242 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/05 (20130101) A61K 31/25 (20130101) A61K 31/047 (20130101) A61K 31/60 (20130101) A61K 31/192 (20130101) A61K 31/717 (20130101) A61K 31/718 (20130101) A61K 31/7016 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 39/395 (20130101) A61K 39/3955 (20130101) A61K 39/39516 (20130101) A61K 47/02 (20130101) A61K 47/12 (20130101) A61K 47/36 (20130101) A61K 47/183 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) Peptides C07K 16/06 (20130101) C07K 16/241 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070492 | Pravetoni |
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| APPLICANT(S) | Hennepin Healthcare Research Institute (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Hennepin Healthcare Research Institute (Minneapolis, Minnesota) |
| INVENTOR(S) | Marco Pravetoni (Minneapolis, Minnesota) |
| ABSTRACT | A method generally includes co-administering to a subject a composition that includes an antigen and a cytokine signaling immunomodulator. The method can be for treating a subject for abuse of a drug, treating a subject for toxicity from drug abuse, treating a subject for infection by a pathogen, treating a subject for a non-communicable disease, or for increasing antibody production against the antigen. The antigen can be component of a vaccine. The cytokine-signaling immunomodulator is effective to improve the subject's immune response to the antigen compared to the subject's immune response to the antigen without the cytokine-signaling immunomodulator. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 16/099093 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) A61K 38/20 (20130101) A61K 39/0018 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 39/385 (20130101) A61K 39/3955 (20130101) A61K 39/39541 (20130101) A61K 39/39541 (20130101) A61K 39/39583 (20130101) A61K 47/643 (20170801) A61K 2039/505 (20130101) A61K 2039/555 (20130101) A61K 2039/6012 (20130101) A61K 2039/6081 (20130101) A61K 2039/55505 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/30 (20180101) A61P 25/36 (20180101) Peptides C07K 16/247 (20130101) C07K 16/248 (20130101) C07K 16/2866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070493 | Jacobs, Jr. et al. |
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| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York) |
| ASSIGNEE(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York) |
| INVENTOR(S) | William R. Jacobs, Jr. (Pelham, New York); Sangeeta Tiwari (Bronx, New York) |
| ABSTRACT | Described herein are methods of determining the efficacy of a candidate tuberculosis vaccine and methods of determining the efficacy of a candidate small organic molecule tuberculosis treatment by administering the candidate tuberculosis vaccine or the small organic molecule tuberculosis treatment to an animal which has been infected with an auxotrophic Mycobacterium. The auxotrophic Mycobacterium has a mycobacterial genome in which (i) argB gene, or a gene encoding a mycobacterial ArgB enzyme, has been fully or partially deleted and (ii) metA gene, or a gene encoding a mycobacterial MetA enzyme, has been fully or partially deleted, wherein the Mycobacterium is sterilized in the absence of arginine and methionine). The methods include quantifying the amount of auxotrophic Mycobacterium to determine the efficacy. |
| FILED | Thursday, April 27, 2023 |
| APPL NO | 18/307998 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/04 (20130101) Original (OR) Class A61K 2039/522 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/52 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070495 | Lusso et al. |
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| APPLICANT(S) | ModernaTX, Inc. (Cambridge, Massachusetts); The United States of America, as represented by the Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | ModernaTX, Inc. (Cambridge, Massachusetts); The United States of America, as represented by the Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | Paolo Lusso (Rockville, Maryland); Peng Zhang (Rockville, Maryland); Elisabeth Narayanan (Cambridge, Massachusetts); Sayda Mahgoub Elbashir (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are methods and compositions for inducing in a subject abroad neutralizing antibody response to human immunodeficiency virus (HIV) infection. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 17/439198 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/53 (20130101) A61K 2039/6018 (20130101) A61K 2039/55516 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070499 | Kagan |
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| FUNDED BY |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jonathan C. Kagan (Brookline, Massachusetts) |
| ABSTRACT | The present invention provides methods and compositions for specific activation of inflammatory responses in dendritic cells (DCs). 1-palmitoyl-2-arachidonyl-sn-glycero phosphorylcholine (PAPC) and its oxidized variant (oxPAPC) were identified to promote DC-mediated immunity, and are provided as adjuvants in immunostimulatory compositions, including vaccines. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 17/730030 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) Original (OR) Class A61K 2039/57 (20130101) A61K 2039/575 (20130101) A61K 2039/55511 (20130101) A61K 2039/55516 (20130101) A61K 2039/55561 (20130101) A61K 2039/55566 (20130101) A61K 2039/55572 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070507 | Spiller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Drexel Univeristy (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Kara Lorraine Spiller (Glenside, Pennsylvania); Amanda Elizabeth Pentecost (Blackwood, New Jersey); Yury Gogotsi (Ivyland, Pennsylvania) |
| ABSTRACT | One aspect of the invention provides a method for reducing inflammation in a patient including locally administering a composition comprising a complex comprising octadecylamine surface-functionalized nanodiamonds with dexamethasone bound to octadecylamine. Another aspect of the invention provides a method for reducing inflammation in a patient comprising locally administering a composition including octadecylamine surface-functionalized nanodiamonds, wherein no therapeutic agent is bound to the nanodiamonds. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 17/653304 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) A61K 47/52 (20170801) A61K 47/6923 (20170801) Original (OR) Class A61K 47/6929 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070513 | Pomper et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSTY (Baltimore, Maryland) |
| INVENTOR(S) | Martin G. Pomper (Baltimore, Maryland); Ronnie Charles Mease (Fairfax, Virginia); Ying Chen (Lutherville-Timonium, Maryland) |
| ABSTRACT | Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis. |
| FILED | Thursday, April 22, 2021 |
| APPL NO | 17/237850 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 51/0402 (20130101) A61K 51/0455 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 275/16 (20130101) C07C 275/18 (20130101) Heterocyclic Compounds C07D 213/61 (20130101) C07D 213/74 (20130101) C07D 213/82 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/2208 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/55 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070530 | LoPresti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Samuel LoPresti (Pittsburgh, Pennsylvania); Bryan N. Brown (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided is a method of preparing an ECM material and the product of the method. The method comprises processing the ECM material with a reactive oxygen species or a reactive nitrogen species. Also provided are methods of use of the product. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/761371 |
| ART UNIT | 1759 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3633 (20130101) A61L 27/3687 (20130101) Original (OR) Class A61L 27/3691 (20130101) A61L 2430/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070628 | Guha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Montefiore Medical Center (Bronx, New York) |
| ASSIGNEE(S) | Montefiore Medical Center (Bronx, New York) |
| INVENTOR(S) | Chandan Guha (Scarsdale, New York); Stephen Barry (Haddonfield, New Jersey) |
| ABSTRACT | Disclosed herein are the systems, devices and methods for treating cancer and metastasis using low energy immune priming. The low energy immune priming includes administering immunopriming energy. The low energy immune priming can be combined with an adjunct therapy. |
| FILED | Monday, May 04, 2020 |
| APPL NO | 16/865761 |
| ART UNIT | 3798 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/485 (20130101) A61B 8/546 (20130101) A61B 8/4218 (20130101) A61B 2018/00613 (20130101) A61B 2018/00994 (20130101) A61B 2090/374 (20160201) Preparations for Medical, Dental, or Toilet Purposes A61K 49/223 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/02 (20130101) A61N 7/00 (20130101) Original (OR) Class A61N 7/02 (20130101) A61N 2007/0004 (20130101) A61N 2007/0052 (20130101) A61N 2007/0078 (20130101) A61N 2007/0082 (20130101) Peptides C07K 14/71 (20130101) C07K 16/2878 (20130101) C07K 2317/75 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070747 | Carmona-Fontaine |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Carlos Carmona-Fontaine (Brooklyn, New York) |
| ABSTRACT | The present invention provides a discrete microenvironment chamber (DIMIC) configured to accurately mimics the microenvironment of poorly perfused tissue. In one embodiment, the DIMIC of the present invention is further designed to allow the extraction of cells and media from different local environments for any type of biochemical analysis. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 17/554369 |
| ART UNIT | 1758 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) Original (OR) Class B01L 2200/0647 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071340 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bionano Genomics, Inc. (San Diego, California) |
| ASSIGNEE(S) | Bionano Genomics, Inc. (San Diego, California) |
| INVENTOR(S) | Han Cao (San Diego, California); Michael David Austin (San Diego, California); Parikshit A. Deshpande (San Diego, California); Mark Kunkel (San Diego, California); Alexey Y. Sharonov (San Diego, California); Michael Kochersperger (San Diego, California) |
| ABSTRACT | Provided are integrated analysis devices having features of macroscale and nanoscale dimensions, and devices that have reduced background signals and that reduce quenching of fluorophores disposed within the devices. Related methods of manufacturing these devices and of using these devices are also provided. |
| FILED | Monday, March 21, 2022 |
| APPL NO | 17/700299 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/10 (20130101) B01L 2200/0663 (20130101) B01L 2200/0689 (20130101) B01L 2300/168 (20130101) B01L 2300/0816 (20130101) B01L 2300/0851 (20130101) B01L 2300/0858 (20130101) B01L 2300/0864 (20130101) B01L 2300/0887 (20130101) B01L 2400/043 (20130101) B01L 2400/086 (20130101) B01L 2400/0415 (20130101) B01L 2400/0442 (20130101) B01L 2400/0487 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 2201/058 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00119 (20130101) Original (OR) Class B81C 2201/019 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2021/0346 (20130101) G01N 2021/6439 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/4981 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071419 | Castor |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trevor Percival Castor (Arlington, Massachusetts) |
| ASSIGNEE(S) | Aphios Corporation (, None) |
| INVENTOR(S) | Trevor Percival Castor (Arlington, Massachusetts) |
| ABSTRACT | This invention is for improving the manufacturing pharmaceutical grade CBD and other cannabinoids following current Good Manufacturing Practices (cGMP) of the US FDA for use in clinical trials for CNS and other indications by the NIH and other researchers. The major cannabinoids in marijuana (Cannabis) and hemp originate from Cannabigerolic Acid (CBGA) present in the biomass of the plant. Plant enzymes that are specific to different strains of biomass converts CBGA to different carboxylic acids of cannabinoids including Cannabidiolic Acid (CBDA) and Δ9-Tetrahydrocannabinolic Acid (Δ9-THCA). These are relatively stable in the growing and fresh-cut plants. These are converted by thermal decarboxylation to Cannabidiol (CBD) and Δ9-Tetrahydrocannabinol (Δ9-THC), carbon dioxide and water. Cannabinoids can be manufactured by first heating the Cannabis biomass to convert carboxylic acids prior to extraction and purification. Alternatively, and preferably because of manufacturing cost and product stability, the carboxylic acids can be first extracted and purified. They can be utilized in the carboxylic acid form or stored in a stable manner until converted to cannabinoids for use in medicine. This invention provides an efficient method for their conversion utilizing a high-pressure reactor under inert conditions. |
| FILED | Sunday, April 24, 2022 |
| APPL NO | 17/727788 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 3/04 (20130101) Acyclic or Carbocyclic Compounds C07C 37/50 (20130101) C07C 37/74 (20130101) C07C 39/19 (20130101) Heterocyclic Compounds C07D 311/80 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071430 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Jun Liu (Baltimore, Maryland); Yingjun Li (Baltimore, Maryland); Kalyan Kumar Pasunooti (Baltimore, Maryland); Wukun Liu (Baltimore, Maryland); Wei Shi (Baltimore, Maryland); Ruojing Li (Baltimore, Maryland); Sarah Head (Baltimore, Maryland) |
| ABSTRACT | Itraconazole, a widely used antifungal drug, has been found to possess potent anti-angiogenic and anti-hedgehog activities, exhibiting promising antitumor activity in several human clinical studies. The wider use of itraconazole in the treatment of cancer, however, has been limited by its potent inhibition of the drug metabolic enzyme CYP3A4 which causes drug-drug interactions. In an effort to eliminate the CYP3A4 inhibition of itraconazole while retaining its anti-angiogenic activity, we synthesized a series of itraconazole derivatives. The newly synthesized analogs of itraconazole were evaluated for their cytotoxicity against human umbilical vein endothelial cells (HUVEC) and their inhibitory activity against CYP3A4 enzyme. |
| FILED | Thursday, October 03, 2019 |
| APPL NO | 17/282378 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/506 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 405/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071436 | Tan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York); The Regents of the University of California (Oakland, California); University of Central Florida Research Foundation, Inc. (Orlando, Florida); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida); The Regents of the University of California (Oakland, California); Memorial Sloan-Kettering Cancer Center (New York, New York); The Broad Institute, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Derek Shieh Tan (New York, New York); Corinne N. Foley (New York, New York); Gustavo Moura-Letts (New York, New York); James McKerrow (New York, New York); Sivaraman Dandapani (Wakefield, Massachusetts); Rahul Edwankar (New York, New York); Alyssa Verano (New York, New York); Debopam Chakrabarti (Winter Springs, Florida); Bracken Roberts (Oviedo, Florida) |
| ABSTRACT | The present disclosure provides compounds of Formula (I′), Formula (II), and Formula (III). The compounds described herein may useful in treating and/or preventing protozoan infections in a subject in need thereof, treating and/or preventing trypanosomal infections (e.g., Trypanosoma cruzi (T. cruzi) or Trypanosoma brucei infections) and/or plasmodial infections in a subject in need thereof, treating and/or preventing diseases in a subject in need thereof (e.g., Chagas disease, malaria, and/or sleeping sickness), and may be useful in treating and/or preventing infectious diseases in a subject in need thereof. Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including a compound described herein. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/532036 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/00 (20180101) A61P 33/06 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071455 | Hagen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | Andrew R. Hagen (Oakland, California); Cheryl A. Kerfeld (Walnut Creek, California); Nancy B. Sloan (Berkeley, California); Markus Sutter (Oakland, California); Bryan H. Ferlez (Haslett, Michigan) |
| ABSTRACT | The present invention provides for a fusion protein comprising (1) a bacterial microcompartment (BMC) shell protein comprising one or more subunit, and (2) a first component of a specific-binding pair, operably linked to the BMC shell protein such that the first component faces (i) a lumen (inside) side, or (ii) outside of a BMC shell formed incorporating the fusion protein and the fusion protein does not disrupt or prevent the folding of the BMC shell protein or the ability of the BMC shell protein to integrate with other BMC shell proteins into a BMC shell; wherein the first component is capable of forming a stable or irreversible interaction with a second component of the specific-binding pair. |
| FILED | Thursday, August 26, 2021 |
| APPL NO | 17/458131 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Separation B01D 15/363 (20130101) B01D 15/3804 (20130101) Peptides C07K 1/22 (20130101) C07K 14/195 (20130101) Original (OR) Class C07K 14/315 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071456 | Schellenberger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AMUNIX PHARMACEUTICALS, INC. (South San Francisco, California) |
| ASSIGNEE(S) | AMUNIX PHARMACEUTICALS, INC. (South San Francisco, California) |
| INVENTOR(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Los Altos Hills, California); Chia-wei Wang (Santa Clara, California); Benjamin Spink (San Carlos, California); Willem P. Stemmer (Los Gatos, California); Nathan Geething (Natick, Massachusetts); Wayne To (Fremont, California); Jeffrey L. Cleland (San Carlos, California) |
| ABSTRACT | The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150426 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/001 (20130101) C07K 14/47 (20130101) Original (OR) Class C07K 14/61 (20130101) C07K 14/545 (20130101) C07K 14/605 (20130101) C07K 14/745 (20130101) C07K 2319/31 (20130101) C07K 2319/35 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/644 (20130101) C12N 9/6437 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071470 | Scheid et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Johannes Scheid (New York, New York); Michel Nussenzweig (New York, New York); Pamela J. Bjorkman (Altadena, California); Ron Diskin (Rehovot, Israel) |
| ABSTRACT | The invention provides broadly neutralizing antibodies directed to epitopes of Human Immunodeficiency Virus, or HIV. The invention further provides compositions containing HIV antibodies used for prophylaxis, and methods for diagnosis and treatment of HIV infection. |
| FILED | Wednesday, February 22, 2023 |
| APPL NO | 18/172836 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/1045 (20130101) Original (OR) Class C07K 16/1063 (20130101) C07K 2317/10 (20130101) C07K 2317/21 (20130101) C07K 2317/34 (20130101) C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071471 | Paul et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | COVALENT BIOSCIENCE INCORPORATED (Tuxedo Park, New York) |
| ASSIGNEE(S) | COVALENT BIOSCIENCE INCORPORATED (Tuxedo Park, New York) |
| INVENTOR(S) | Sudhir Paul (Missouri City, Texas); Stephanie Planque (Houston, Texas); Yasuhiro Nishiyama (Houston, Texas); Eric L. Brown (Houston, Texas); Keri C. Smith (Houston, Texas); Hiroaki Taguchi (Houston, Texas) |
| ABSTRACT | Disclosed are antibodies (immunoglobulins) and fragments thereof that hydrolyze or bind polypeptide antigens belonging to Staphylococcus aureus, hepatitis C virus, human immunodeficiency virus and Alzheimer's disease. Also disclosed are novel methods to improve the antigen reactivity of the immunoglobulins and to treat a pathophysiological condition using the immunoglobulins as therapeutics. |
| FILED | Monday, May 14, 2018 |
| APPL NO | 15/978801 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 16/109 (20130101) C07K 16/1063 (20130101) C07K 16/1271 (20130101) C07K 2317/52 (20130101) C07K 2317/56 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) C07K 2317/622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6854 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071474 | Luk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Kelvin C. Luk (Philadelphia, Pennsylvania); Virginia M. Y. Lee (Philadelphia, Pennsylvania); John Q. Trojanowski (Philadelphia, Pennsylvania); Kurt R. Brunden (Media, Pennsylvania); Dustin Covell (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure provides monoclonal antibodies that bind α-Synuclein. In certain aspects, the antibodies preferentially bind to α-Synuclein fibrils over α-Synuclein monomer. In other aspects, the invention comprises a method of treating α-Synucleopathic disease in a subject, comprising administering any of the antibodies of the invention to the subject. In yet other aspects, the invention comprises methods of detecting α-Synuclein fibrils using any of the antibodies of the invention. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/572309 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0029 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/577 (20130101) G01N 33/6896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071616 | O'Farrell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Altratech Limited (Limerick, Ireland); The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | Altratech Limited (Limerick, Ireland); The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | Brian O'Farrell (Watergrasshill, Ireland); Claire O'Connell (Stamullen, Ireland); Kaylyn Oshaben (Summerhill, Pennsylvania); Daniel Appella (Bethesda, Maryland) |
| ABSTRACT | A method of target enrichment or depletion from a sample with an analyte is described. A probe has one of a left-handed PNA pair and a targeting moiety, in which the left-handed PNA pair are a complementary pair of PNAs that are chiral and have a cyclic backbone modification that induces a left-handed helical structure. A capture surface has the other of the left-handed PNA pair; and the left-handed PNA pair bind to hybridize the probe to the capture surface, which may be a magnetic bead. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/193652 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1013 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071632 | Munir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Shirin Munir (Potomac, Maryland); Linda G. Brock (Wyckoff, New Jersey); Ursula J. Buchholz (Silver Spring, Maryland); Peter L. Collins (Silver Spring, Maryland) |
| ABSTRACT | Disclosed are live, chimeric non-human Mononegavirales vectors that allow a cell to express at least one protein from at least one human pathogen. In addition, compositions comprising the vectors, methods and kits for eliciting an immune response in a host, and methods of making the vectors are disclosed, in accordance with embodiments of the invention. |
| FILED | Tuesday, April 23, 2019 |
| APPL NO | 17/049916 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/155 (20130101) A61K 2039/543 (20130101) A61K 2039/5256 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2760/18534 (20130101) C12N 2760/18544 (20130101) C12N 2760/18551 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071634 | Boehm et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Manfred Boehm (Bethesda, Maryland); Guibin Chen (Ellicott City, Maryland); Mahendra Rao (Timonium, Maryland); Andre Larochelle (Bethesda, Maryland) |
| ABSTRACT | Described herein are cells, cell culture methods, and cell culture media compositions useful for producing and maintaining iPSC-derided cell lines that are of higher purity and maintain cell type integrity better than current iPSC-derived cell lines. Also disclosed are methods of using the described cells and media, such as therapeutic methods of use for the described cells. The described cells include iPSC-derived mesodermal precursor cells (MPC), which itself may differentiate into at least four different cell types. When cultured under appropriate conditions, the mesodermal precursor cells can be used to produce hematopoietic stem cells (HSC), mesenchymal stem cells (MSC), smooth muscle cells (SMC), or unlimited functional endothelial cells (UFEC). One characteristic that makes the described cells desirable is that they can be maintained in culture for a number of days, or passages, without changing phenotype through differentiation. |
| FILED | Thursday, June 03, 2021 |
| APPL NO | 17/337978 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0607 (20130101) Original (OR) Class C12N 5/0647 (20130101) C12N 5/0661 (20130101) C12N 5/0662 (20130101) C12N 5/0696 (20130101) C12N 2500/05 (20130101) C12N 2500/30 (20130101) C12N 2500/36 (20130101) C12N 2500/42 (20130101) C12N 2500/44 (20130101) C12N 2500/90 (20130101) C12N 2501/26 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2501/165 (20130101) C12N 2506/03 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071640 | Gordon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Wendy R. Gordon (Minneapolis, Minnesota); Eric Aird (Minneapolis, Minnesota); Klaus Lovendahl (Minneapolis, Minnesota) |
| ABSTRACT | Materials and methods for gene editing using improved targeted endonucleases and endonuclease systems (e.g., Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) endonuclease systems) are provided herein. |
| FILED | Tuesday, July 05, 2022 |
| APPL NO | 17/810691 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/87 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071656 | Stoeckius et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New York Genome Center, Inc. (New York, New York) |
| ASSIGNEE(S) | New York Genome Center, Inc. (New York, New York) |
| INVENTOR(S) | Marlon Stoeckius (New York, New York); Peter Smibert (New York, New York); Brian Houck-Loomis (New York, New York) |
| ABSTRACT | Compositions, kits and methods are described that comprise one or more constructs, each construct comprising a ligand attached or conjugated to a polymer construct, e.g., an oligonucleotide sequence, by a linker, each ligand binding specifically to a single target located in or on the surface of a cell. The polymer construct comprises a) an Amplification Handle; b) a Barcode that specifically identifies a single ligand; c) an optional Unique Molecular Identifier that is positioned adjacent to the Barcode on its 5′ or 3′ end; and d) an Anchor for hybridizing to a complementary sequence, e.g., for generation of a double-stranded oligonucleotide. These compositions are used in methods, including high throughput methods, for detecting one or more targets or epitopes in a biological sample. These compositions are also used in a high throughput method for characterizing a cell by simultaneous detection of one or more epitopes located in or on the cell and its transcriptome. |
| FILED | Friday, April 30, 2021 |
| APPL NO | 17/245479 |
| ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1093 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6804 (20130101) C12Q 1/6844 (20130101) Original (OR) Class C12Q 2531/113 (20130101) C12Q 2535/122 (20130101) C12Q 2537/143 (20130101) C12Q 2563/159 (20130101) C12Q 2563/179 (20130101) C12Q 2565/519 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071663 | Gierahn et al. |
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| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Todd M. Gierahn (Brookline, Massachusetts); J. Christopher Love (Somerville, Massachusetts); Travis K. Hughes (Cambridge, Massachusetts); Marc H. Wadsworth, II (Cambridge, Massachusetts); Alexander K. Shalek (Lexington, Massachusetts); Shaina Carroll (Cambridge, Massachusetts) |
| ABSTRACT | The present application provides a method of assembling a container for one or multiple parallel steps of biochemical analysis on one or more cells comprising performing molecular bonding of a porous membrane on an apical or basal surface of an array having a plurality of wells, wherein the molecular bonding substantially isolates each well from adjacent wells. |
| FILED | Tuesday, January 17, 2017 |
| APPL NO | 16/070505 |
| ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/00572 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 2537/143 (20130101) C12Q 2563/149 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071672 | Jarrard et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Reseach Foundation (Madison, Wisconsin) |
| INVENTOR(S) | David Frazier Jarrard (Madison, Wisconsin); Bing Yang (Madison, Wisconsin) |
| ABSTRACT | A method of detecting the presence of a prostate cancer field defect in a human subject. The method includes (a) obtaining genomic DNA from the human subject and (b) determining methylation status in at least one target region selected from the group consisting of PLA2G16, CAV1, EVX1, MCF2L, FGF1, NCR2, WNT2, EXT1, and SPAG4, wherein methylation changes indicate the presence of prostate cancer or a prostate cancer field defect, wherein the change is relative to tissue from a second human subject who does not have prostate cancer. |
| FILED | Tuesday, September 14, 2021 |
| APPL NO | 17/474174 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6853 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2337/00 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072283 | Hendon et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Christine Hendon (Bronx, New York); Rajinder Singh-Moon (Mastic, New York); James McLean (New York, New York); Soo Young Park (Seoul, South Korea) |
| ABSTRACT | An exemplary catheter can be provided, which can include, for example a source fiber(s) configured to (i) receive a near infrared spectroscopic (NIRS) radiation, and (ii) provide the NIRS radiation to a portion(s) of a sample(s), a detection fiber(s) configured to receive a return radiation from the sample(s) that can be based on the NIRS radiation that was provided to the portion(s) of the sample(s), and an ablation electrode(s) configured to ablate the sample(s) based on the return radiation. The source fiber(s), the detection fiber(s), and the ablation electrode(s) can be integrated into the single sheath. The ablation electrode(s) can be a radiofrequency ablation electrode. |
| FILED | Friday, June 19, 2020 |
| APPL NO | 16/906429 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/0086 (20130101) A61B 18/1492 (20130101) A61B 2018/00577 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/359 (20130101) G01N 21/474 (20130101) G01N 21/3563 (20130101) Original (OR) Class G01N 2021/4709 (20130101) G01N 2021/4745 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072400 | Conolly et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Steven Conolly (Walnut Creek, California); Carlos Rinaldi (Gainesville, Florida); Bo Zheng (Seattle, Washington); Prashant Chandrasekharan (Berkeley, California); Daniel Hensley (Emeryville, California); Shehaab Savliwala (Gainesville, Florida); Zhi Wei Tay (Singapore, Singapore); Rohan Deepak Dhavalikar (Hillsboro, Oregon) |
| ABSTRACT | A magnetic particle imaging system that includes a magnetic field generating system with at least one magnet and providing a gradient magnetic field within an observation region such that the gradient magnetic field has a dynamic field-free region (FFR) for an object under observation having strongly-interacting magnetic particles distributed therein. The magnetic field generating system also includes a drive field and a slow shift field that dynamically shifts the FFR across a field of view (FOV) within the observation region, where the trajectory of the drive field accommodates for a coercivity of the strongly-interacting magnetic particles by ensuring that the particles in the FOV are saturated to a full coercivity field prior to traversing to an opposite-polarity of coercivity. The magnetic particle imaging system also includes a detection system proximate the observation region and configured to detect a signal from the strongly-interacting magnetic particles. The magnetic particle imaging system further includes signal processor in communication with the detection system, configured to receive and process the detected signal to remove a coercivity shift due to the coercivity of the strongly-interacting magnetic particles, and convert the processed detection signal into an image of the strongly-interacting magnetic particles. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 17/629301 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0515 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/1276 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072403 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Yi Wang (New York, New York); Zhe Liu (New York, New York); Jinwei Zhang (New York, New York); Qihao Zhang (New York, New York); Junghun Cho (New York, New York); Pascal Spincemaille (New York, New York) |
| ABSTRACT | Exemplary methods for quantitative mapping of physical properties, systems and computer-accessible medium can be provided to generate images of tissue magnetic susceptibility, transport parameters and oxygen consumption from magnetic resonance imaging data using the Bayesian inference approach, which minimizes a data fidelity term under a constraint of a structure prior knowledge. The data fidelity term is constructed directly from the magnetic resonance imaging data. The structure prior knowledge can be characterized from known anatomic images using image feature extraction operation or artificial neural network. Thus, according to the exemplary embodiment, system, method and computer-accessible medium can be provided for determining physical properties associated with at least one structure. |
| FILED | Monday, September 25, 2023 |
| APPL NO | 18/474048 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/7221 (20130101) A61B 5/7267 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) Original (OR) Class G01R 33/56536 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/10088 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072479 | Hu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Ye Hu (Scottsdale, Arizona); Dali Sun (Tempe, Arizona) |
| ABSTRACT | A mobile phone-based dark field microscope (MDFM) apparatus suitable for quantifying nanoparticle signals is provided. The MDFM apparatus includes an electrically operated light source, a dark-field condenser, a slide housing configured to receive an analytical slide, and an adapter housing configured to receive an objective lens and receive a portable electronic communication device. The slide housing positions the analytical slide between the objective lens and the dark-field condenser. The adapter housing registers the objective lens with a camera lens of the portable electronic communication device. A method for performing a biological quantitative study using the dark-field microscope apparatus is further provided. |
| FILED | Wednesday, December 21, 2022 |
| APPL NO | 18/069572 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/51 (20130101) G01N 33/587 (20130101) G01N 2201/0221 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0008 (20130101) Original (OR) Class G02B 21/10 (20130101) G02B 21/025 (20130101) G02B 21/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072480 | Kang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Dongkyun Kang (Tucson, Arizona); Cheng Gong (Tucson, Arizona) |
| ABSTRACT | Devices, systems and methods are described that can be used to develop confocal microscopes with high lateral resolution. One example confocal microscope includes a first dispersion element that receives a light beam and to produce illumination beams with different spectral components, and an objective that receives reflected light upon reflection of the illumination beams from a target. The confocal microscope further includes a second dispersion element that receives the reflected light after propagation through in the objective lens, and a third dispersion element that receives the dispersed light associated with the second dispersion element and provides an output light to a camera lens for focusing onto a detector. The second and the third dispersion elements are positioned such that each point on the detector is conjugate to a corresponding single point on the target. Some applications of the disclosed confocal microscopes include skin disease diagnosis and imaging of freshly-excised tissues. |
| FILED | Friday, January 17, 2020 |
| APPL NO | 17/419921 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/28 (20130101) Optical Elements, Systems, or Apparatus G02B 21/02 (20130101) G02B 21/0032 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072481 | Dickensheets et al. |
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| FUNDED BY |
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| APPLICANT(S) | MONTANA STATE UNIVERSITY (Bozeman, Montana); MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MONTANA STATE UNIVERSITY (Bozeman, Montana); MEMORIAL SLOAN-KETTERING CANCER (New York, New York) |
| INVENTOR(S) | David Dickensheets (Bozeman, Montana); Milind Rajadhyaksha (New York, New York) |
| ABSTRACT | A device for viewing a target, the device including a housing, an objective lens positioned within the housing, where the objective lens has a first lens group including at least a first lens and a second lens group including at least a second lens, the first lens positioned closer to the target than the second lens, and a camera positioned within the objective lens between the first lens and the second lens, where the camera is configured to provide images of the target located near a focal point of the objective lens, and wherein the arrangement of the first lens, the second lens, and the camera provides for simultaneous capture of a first image of a surface of the target and a second image of a sub-surface cellular structure of the target. |
| FILED | Monday, April 11, 2022 |
| APPL NO | 17/717774 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0068 (20130101) A61B 5/0075 (20130101) A61B 5/0077 (20130101) A61B 5/444 (20130101) Optical Elements, Systems, or Apparatus G02B 21/02 (20130101) G02B 21/06 (20130101) G02B 21/0008 (20130101) G02B 21/0028 (20130101) G02B 21/0036 (20130101) G02B 21/361 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073492 | Shi et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Luyao Shi (New Haven, Connecticut); Chi Liu (Orange, Connecticut); John Onofrey (Woodbridge, Connecticut); Hui Liu (Beijing, China PRC) |
| ABSTRACT | A system for estimating attenuation coefficients from only single photon emission computed tomography (SPECT) emission data using deep neural networks includes an artificial neural network based upon machine learning system estimating attenuation maps for SPECT emission data, and associated attenuation correction method. |
| FILED | Friday, April 17, 2020 |
| APPL NO | 17/594364 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 11/003 (20130101) Original (OR) Class G06T 2207/10108 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073541 | Otwinowski et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Zbyszek Otwinowski (Dallas, Texas); Raquel Bromberg (Dallas, Texas); Dominika Borek (Dallas, Texas) |
| ABSTRACT | Methods for correcting one or more image aberrations in an electron microscopy image, including cryo-EM images, are provided. The method includes obtaining a plurality of electron microscope (EM) images of an internal reference grid sample having one or more known properties, the plurality of electron microscope images obtained for a plurality of optical conditions and for a plurality of coordinated beam-image shifts. The method may also include, among other features, determining an aberration correction function that predicts aberrations for every point in the imaged area using kernel canonical correlation analysis (KCCA). |
| FILED | Monday, August 10, 2020 |
| APPL NO | 17/633133 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/80 (20240101) Original (OR) Class G06T 2207/10061 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/222 (20130101) H01J 2237/223 (20130101) H01J 2237/2826 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073559 | Asiedu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Mercy Asiedu (Durham, North Carolina); Nirmala Ramanujam (Durham, North Carolina); Guillermo Sapiro (Durham, North Carolina) |
| ABSTRACT | A method for automated detection of cervical pre-cancer includes: providing at least one cervigram; pre-processing the at least one cervigram; extracting features from the at least one pre-processed cervigram; and classifying the at least one cervigram as negative or positive for cervical pre-cancer based on the extracted features. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/282093 |
| ART UNIT | 2635 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/000094 (20220201) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/136 (20170101) G06T 7/168 (20170101) G06T 2207/20024 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20132 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073560 | Madabhushi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia); University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Sepideh Azarianpour Esfahani (Cleveland Heights, Ohio); Haider Mahdi (Wexford, Pennsylvania) |
| ABSTRACT | Various embodiments of the present disclosure are directed towards a method for generating a risk group classification for an African American (AA) patient. The method includes extracting a first plurality of architectural features from a digitized H&E slide image of the AA patient. A risk score for the AA patient is generated based on the first plurality of architectural features, where the risk score is prognostic of overall survival (OS) of the AA patient. The risk group classification is generated for the AA patient, where generating the risk group classification includes classifying the AA patient into either a high risk group or a low risk group based on the risk score, where the high risk group indicates the AA patient will die before a threshold date and the low risk group indicates the AA patient will die after or on the threshold date. |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/671882 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/30024 (20130101) G06T 2207/30096 (20130101) Image or Video Recognition or Understanding G06V 10/764 (20220101) G06V 10/774 (20220101) G06V 20/698 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073561 | Buckler et al. |
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| FUNDED BY |
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| APPLICANT(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| INVENTOR(S) | Andrew J. Buckler (Boston, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts); Mark A. Buckler (Wenham, Massachusetts); Vladimir Valtchinov (Waban, Massachusetts); David S. Paik (Moon Bay, California) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Wednesday, February 08, 2023 |
| APPL NO | 18/166284 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/24 (20230101) G06F 18/211 (20230101) G06F 18/2148 (20230101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 3/00 (20130101) G06T 5/73 (20240101) G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10048 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10101 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/30096 (20130101) G06T 2207/30104 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/764 (20220101) G06V 20/69 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12075564 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Chi Hwan Lee (West Lafayette, Indiana); Laurent Couetil (West Lafayette, Indiana); Tae Hoo Chang (Beavercreek, Ohio); Semih Akin (West Lafayette, Indiana); Martin Byung-Guk Jun (West Lafayette, Indiana) |
| ABSTRACT | Electronic textiles and methods of fabrication electronic textiles. Nanoparticles of a conductive material are sprayed along a conductive path into a fabric material so as to penetrate into the fabric. A layer of a second conductor material is coated over the nanoparticles along the conductive path. A layer of an insulator material is coated over the layer of the second conductor material so as to encapsulate the conductive path and form a trace. An electrode configured to contact a subject wearing the fabric material includes a layer of a third conductor material coated over the layer of the second conductor and electrically coupled with the conductive path. An electrical connector is secured to the fabric material and electrically coupled with the conductive path. The nanoparticles are sprayed onto the fabric material using a dual regime spray process implemented with a dual regime spray system. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/823021 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/27 (20210101) A61B 2503/40 (20130101) A61B 2562/0215 (20170801) A61B 2562/0285 (20130101) Treating Textile Materials Using Liquids, Gases or Vapours D06B 11/0059 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/65 (20130101) D06M 11/83 (20130101) D06M 15/693 (20130101) D06M 23/08 (20130101) D06M 2101/06 (20130101) D06M 2101/32 (20130101) D06M 2101/38 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2201/02 (20130101) D10B 2331/04 (20130101) D10B 2331/10 (20130101) D10B 2401/16 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/28 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/038 (20130101) Original (OR) Class H05K 1/092 (20130101) H05K 3/14 (20130101) H05K 2201/10151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE50096 | Egan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TargaGenix, Inc. (Stony Brook, New York); The Research Foundation for the State University New York (Albany, New York); Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | The Research Foundation for the State University New York (, None); Targagenix, Inc. (Stony Brook, New York); Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | James E. Egan (Stony Brook, New York); Iwao Ojima (Port Jefferson, New York); Mansoor M. Amiji (Attleboro, Massachusetts); Galina Ivanovna Botchkina (Stony Brook, New York) |
| ABSTRACT | A composition of an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water nanoemulsion (NE) drug delivery system. A method of treating cancer by administering an effective amount of a pharmaceutical composition including a PUFA-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system to a subject in need of treatment, and treating cancer. A method of overcoming multidrug resistance by exposing a multidrug resistant cell to an effective amount of a pharmaceutical composition including an omega-3 polyunsaturated fatty acid (PUFA)-taxoid conjugate encapsulated in an oil-in-water NE drug delivery system, and inducing the death of the multidrug resistant cell. A method of eliminating a cancer stem cell. Methods of reducing stemness of a cancer stem cell, retaining drug in the body, and providing a slower release profile. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/179720 |
| ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) A61K 9/1075 (20130101) Original (OR) Class A61K 31/337 (20130101) A61K 47/12 (20130101) A61K 47/44 (20130101) A61K 47/542 (20170801) A61K 47/6907 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12070095 | Fasel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | Government of the United States as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin P Fasel (East Bridgewater, Massachusetts); David S Colanto (Natick, Massachusetts); Robert V Dilalla (Walpole, Massachusetts); Tony Kayhart (Cambridge, Massachusetts) |
| ABSTRACT | A functionally graded structure for a protective device includes a plurality of lattice structures including at least a first lattice structure having a first geometry and a second lattice structure having a second geometry. The first lattice structure with the first geometry has a first compression response property and the second lattice structure with the second geometry has a second compression response property that is different from the first compression response property. |
| FILED | Friday, March 11, 2022 |
| APPL NO | 17/692445 |
| ART UNIT | 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Hats; Head Coverings A42B 3/12 (20130101) A42B 3/063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070282 | Farritor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Shane Farritor (Lincoln, Nebraska); Tom Frederick (Gretna, Nebraska); Kearney Lackas (Lincoln, Nebraska); Joe Bartels (Pittsburgh, Pennsylvania); Jacob Greenburg (Lincoln, Nebraska) |
| ABSTRACT | The various embodiments herein relate to robotic surgical systems and devices that use force and/or torque sensors to measure forces applied at various components of the system or device. Certain implementations include robotic surgical devices having one or more force/torque sensors that detect or measure one or more forces applied at or on one or more arms. Other embodiments relate to systems having a robotic surgical device that has one or more sensors and an external controller that has one or more motors such that the sensors transmit information that is used at the controller to actuate the motors to provide haptic feedback to a user. |
| FILED | Tuesday, July 07, 2020 |
| APPL NO | 16/922560 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Original (OR) Class A61B 34/76 (20160201) A61B 2090/064 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/1602 (20130101) B25J 9/1633 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/36432 (20130101) G05B 2219/39181 (20130101) G05B 2219/39194 (20130101) G05B 2219/39321 (20130101) G05B 2219/40619 (20130101) G05B 2219/45117 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/27 (20130101) Y10S 901/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070304 | Isaiah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University Of Maryland, Baltimore (Baltimore, Maryland); Sonosa Medical, Inc. (Baltimore, Maryland) |
| ASSIGNEE(S) | University Of Maryland, Baltimore (Baltimore, Maryland); Sonosa Medical, Inc. (Baltimore, Maryland) |
| INVENTOR(S) | Amal Isaiah (Hanover, Maryland); Jeffrey S. Wolf (Owings Mills, Maryland); Stephen Restaino (Columbia, Maryland) |
| ABSTRACT | A method and system detects a hypoxic condition during an obstruction of an airway of a subject to detect and treat obstructive sleep apnea (OSA) in the subject. The method and system includes an organ stimulating transducer configured for placement in a vicinity of an organ of the subject to stimulate the organ and remove the obstruction when OSA is detected. |
| FILED | Thursday, January 24, 2019 |
| APPL NO | 16/964736 |
| ART UNIT | 3798 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/742 (20130101) A61B 5/0826 (20130101) Original (OR) Class A61B 5/4818 (20130101) A61B 5/4836 (20130101) A61B 5/6822 (20130101) A61B 5/7405 (20130101) A61B 5/7455 (20130101) A61B 5/14542 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) A61N 2007/0026 (20130101) A61N 2007/0052 (20130101) A61N 2007/0073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070444 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Rong Li (Washington, District of Columbia); Bin Yuan (Hefei, China PRC); Kate Ida Lathrop (San Antonio, Texas) |
| ABSTRACT | The present invention provides methods and compositions for modulating molecular markers, and hence treating or preventing breast cancer (e.g., triple-negative breast cancer) and melanoma with a pharmaceutically effective amount of S-equol or a pharmaceutical composition comprising S-equol. The S-equol may be administered alone or in combination with one or more cytotoxic or immunotherapeutic compound or molecule. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 17/535125 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) Original (OR) Class A61K 39/39541 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070462 | Du et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Yang Du (Bethesda, Maryland); Nhu Nguyen (Bethesda, Maryland) |
| ABSTRACT | Chemical compounds for the treatment of myeloid neoplasms and solid tumors are described, where the compounds were identified through a screening process assessing the binding affinity of the compounds to a synthesized fragment of Setbp1 protein. |
| FILED | Wednesday, May 22, 2019 |
| APPL NO | 17/057063 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/475 (20130101) A61K 31/517 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/4702 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070465 | Zuo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| ASSIGNEE(S) | Ting Therapeutics LLC (Omaha, Nebraska) |
| INVENTOR(S) | Jian Zuo (Omaha, Nebraska); Jeff North (Omaha, Nebraska); Santanu Hati (Omaha, Nebraska); Marisa Laura Zallocchi (Omaha, Nebraska) |
| ABSTRACT | In one aspect, use of compounds as active agents to treat a hearing impairment and to prevent a hearing impairment, and methods of treating and/or preventing hearing impairments or disorders using the compositions are disclosed. (E)-1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-S,6-dihydropyridin-2(1H)-one and derivatives exhibit excellent protection against antibiotic-induced hearing loss in zebrafish and mice. In one aspect, (E)-1-(3-(3,4,5-trimethoxy phenyl)acryloyl)-S,6-dihydropyridin-2(1H)-one and derivatives can be used as a therapy for the treatment and/or prevention of hearing loss. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Wednesday, September 15, 2021 |
| APPL NO | 18/031998 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/45 (20130101) A61K 31/55 (20130101) Original (OR) Class A61K 31/397 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070468 | Shawber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Carrie J. Shawber (Washington, New Jersey); June K. Wu (New York, New York); Ajit Muley (San Mateo, California) |
| ABSTRACT | Provided herein are methods and compositions for treating and preventing vascular malformations including lymphatic, venous, capillary, arteriovenous, and combinations thereof. Methods of treatment and prevention include the administration of proteasome inhibitors, omipalisib, disulfiram, and agents which target genes in the PI3K/AKT/mTOR or RAS/RAF/MAPK pathways, including but not limited to Pik3ca, Pik3r3, Tsc2, Rasa1, Map2k2, and Glmn. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 17/984734 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/69 (20130101) Original (OR) Class A61K 31/145 (20130101) A61K 31/407 (20130101) A61K 31/501 (20130101) A61K 38/06 (20130101) A61K 38/07 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070513 | Pomper et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSTY (Baltimore, Maryland) |
| INVENTOR(S) | Martin G. Pomper (Baltimore, Maryland); Ronnie Charles Mease (Fairfax, Virginia); Ying Chen (Lutherville-Timonium, Maryland) |
| ABSTRACT | Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis. |
| FILED | Thursday, April 22, 2021 |
| APPL NO | 17/237850 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 51/0402 (20130101) A61K 51/0455 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 275/16 (20130101) C07C 275/18 (20130101) Heterocyclic Compounds C07D 213/61 (20130101) C07D 213/74 (20130101) C07D 213/82 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/2208 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/55 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071409 | Watowich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas (Austin, Texas) |
| INVENTOR(S) | Stanley Watowich (Galveston, Texas); Harshini Neelakantan (Galveston, Texas); Hua-Yu Wang (Galveston, Texas); Stanton Mchardy (Galveston, Texas) |
| ABSTRACT | The present invention relates to quinoline derived small molecule inhibitors of nicotinamide N-methyltransferase (NNMT), the preparation thereof and uses thereof. |
| FILED | Tuesday, June 07, 2022 |
| APPL NO | 17/834847 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 215/10 (20130101) C07D 215/26 (20130101) C07D 215/42 (20130101) Original (OR) Class C07D 405/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071410 | Gupton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| ASSIGNEE(S) | Virginia Commonwealth University (Richmond, Virginia) |
| INVENTOR(S) | Frank B. Gupton (Richmond, Virginia); Saeed Ahmad (Chesterfield, Virginia); Hari P. R. Gunuru (Henrico, Virginia); Nakul S. Telang (Richmond, Virginia) |
| ABSTRACT | Cost effective, semi-continuous flow methods and systems for synthesizing the antimalarial drug hydroxychloroquine (HCQ) in high yield are provided. The synthesis method that uses simple, inexpensive reagents to obtain the crucial intermediate 5-(ethyl(2-hydroxyethyl)-amino)pentan-2-one, vertical-integration of the starting material 5-iodopentan-2-one and the integration of continuous stirred tank reactors. |
| FILED | Monday, February 25, 2019 |
| APPL NO | 16/975434 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/0492 (20130101) B01J 19/0013 (20130101) B01J 19/0066 (20130101) B01J 19/245 (20130101) B01J 19/1862 (20130101) B01J 2219/0004 (20130101) B01J 2219/00033 (20130101) Heterocyclic Compounds C07D 215/46 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071583 | Sharar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Darin J. Sharar (Silver Spring, Maryland); Ronald Warzoha (Severna Park, Maryland); Brian Donovan (Annapolis, Maryland) |
| ABSTRACT | A heat exchange component includes a part configured for exchanging thermal energy, the part is formed of at least one solid state Martensitic transformation phase change material which is configured to readily undergo a solid-solid martensitic transformation from one crystalline structure to another different crystalline structure during a change in temperature in the normal and/or anticipated operating temperatures of the heat exchange component. In some embodiments, the system further includes a temporally-evolving external temperature/heat source which changes the temperature and resultant phase of the solid-state phase change material. The temporally-evolving external temperature/heat source may involve a solid conducting material or electronic/photonic component, a fluid, a plasma, and/or a radiation source. The heat exchange component may be configured as a flat plate, tube, finned structure, porous structure, graded structure, cold plate, heat exchanger, condenser, evaporator, or any component generally regarded as a thermal energy storage or heat transfer structure in various embodiments. |
| FILED | Wednesday, June 24, 2020 |
| APPL NO | 16/910652 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) Original (OR) Class C09K 5/063 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071626 | Freedman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Jennifer Freedman (Durham, North Carolina); Brendon Patierno (Durham, North Carolina); Bonnie LaCroix (Durham, North Carolina); Timothy Robinson (Durham, North Carolina); Bruce Sullenger (Durham, North Carolina); Daniel George (Durham, North Carolina); Steven Patierno (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides methods and compositions for the treatment of cancer. In some aspects, the present disclosure provides splice-switching oligonucleotides that downregulate AR or EGFR expression and methods of using these splice-switching oligonucleotides to treat cancer. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 17/464474 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) A61K 31/7125 (20130101) A61K 45/06 (20130101) A61K 48/0066 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/1136 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/3521 (20130101) C12N 2320/31 (20130101) C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071663 | Gierahn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Todd M. Gierahn (Brookline, Massachusetts); J. Christopher Love (Somerville, Massachusetts); Travis K. Hughes (Cambridge, Massachusetts); Marc H. Wadsworth, II (Cambridge, Massachusetts); Alexander K. Shalek (Lexington, Massachusetts); Shaina Carroll (Cambridge, Massachusetts) |
| ABSTRACT | The present application provides a method of assembling a container for one or multiple parallel steps of biochemical analysis on one or more cells comprising performing molecular bonding of a porous membrane on an apical or basal surface of an array having a plurality of wells, wherein the molecular bonding substantially isolates each well from adjacent wells. |
| FILED | Tuesday, January 17, 2017 |
| APPL NO | 16/070505 |
| ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/00572 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Original (OR) Class C12Q 1/6874 (20130101) C12Q 2537/143 (20130101) C12Q 2563/149 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071668 | Tsalik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Ephraim L. Tsalik (Cary, North Carolina); Geoffrey S. Ginsburg (Durham, North Carolina); Christopher W. Woods (Durham, North Carolina); Ricardo Henao Giraldo (Durham, North Carolina); Rachel A. Myers (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure provides methods for determining whether a subject has sepsis, or is at risk of developing sepsis, and methods of treating the subject based on the determination. Also provided are methods for determining an increased risk of mortality in a subject with sepsis or suspected of having sepsis, and methods of treating the subject based on the determination. Systems useful for the same are also provided. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/651579 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071913 | Sweeney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Patrick C. Sweeney (Indianapolis, Indiana); Douglas J. Snyder (Indianapolis, Indiana); Kerry J. Lighty (Plainfield, Indiana); Scott Schwenker (Indianapolis, Indiana) |
| ABSTRACT | A bypass duct assembly for a gas turbine engine includes a bypass duct, a heat exchanger assembly, and an inlet cowl. The bypass duct is configured to direct bypass air around an engine core of the gas turbine engine. The heat exchanger assembly includes a heat exchanger located in the bypass duct and configured to transfer heat to the bypass air. The inlet cowl is coupled with the bypass duct and the heat exchanger assembly. The inlet cowl includes a cowl duct configured to collect a first portion of the bypass air and conduct the first portion of the bypass air into the heat exchanger and a flow diverter that guides a second portion of the bypass air around the heat exchanger. |
| FILED | Monday, July 31, 2023 |
| APPL NO | 18/228267 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Jet-propulsion Plants F02K 3/075 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/213 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072220 | McFall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Brian C McFall (Vicksburg, Mississippi); David L Young (Kill Devil Hills, North Carolina); Duncan B Bryant (Vicksburg, Mississippi); Timothy L Welp (Vicksburg, Mississippi) |
| ABSTRACT | In one embodiment, a field-deployable acoustic camera system is provided for measuring a two-dimensional velocity field in a large scale flow in a turbid environment. The system includes an acoustic camera and a concentrator lens. The concentrator lens operates to reduce a spreading angle of the acoustic camera. The system is configured to apply planar cross-correlation velocimetry to collected images of native micro-bubble and/or suspended particle motion collected in turbid environments such as lake circulation, riverine, estuarine, and coastal flows, as well as turbid flows that occur near dredging operations. |
| FILED | Tuesday, January 08, 2019 |
| APPL NO | 16/242882 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/002 (20130101) G01F 1/662 (20130101) Original (OR) Class Electric Digital Data Processing G06F 3/147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072336 | Tajbakhsh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California); TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California); Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Jian Tajbakhsh (Encino, California); Darko Stefanovski (West Chester, Pennsylvania) |
| ABSTRACT | In certain embodiments, this application discloses methods for the diagnosis and prognosis of prostate cancer. In some embodiments, the invention takes advantage of the combinatorial utility of certain biomarkers to prognose and diagnose prostate cancer at an early stage. In certain embodiments, the methods described herein do not require the selection of cells from a particular tissue compartment, and are therefore suitable for analysis of cancer tissue in which compartmentalization is lost. |
| FILED | Friday, October 20, 2017 |
| APPL NO | 16/342297 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 21/6428 (20130101) G01N 21/6447 (20130101) G01N 21/6458 (20130101) G01N 33/57434 (20130101) Original (OR) Class G01N 2001/302 (20130101) G01N 2021/6439 (20130101) G01N 2201/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072396 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Nian-Xiang Sun (Winchester, Massachusetts); Neville Sun (Boston, Massachusetts); Xianfeng Lian (Boston, Massachusetts); Huaihao Chen (Boston, Massachusetts) |
| ABSTRACT | A solidly mounted resonator (SMR)-based magnetoelectric (ME) antenna comprises a substrate, a Bragg reflector disposed on the substrate, a magnetostrictive/piezoelectric ME composite element disposed on the Bragg reflector, a first electrically conductive contact and a second electrically conductive contact. The first contact is disposed between the Bragg reflector and the magnetostrictive/piezoelectric ME composite element and electrically coupled to a bottom surface of the magnetostrictive/piezoelectric ME composite element. The second contact is disposed on top of the magnetostrictive/piezoelectric ME composite element and electrically coupled to the top of the magnetostrictive/piezoelectric ME composite element. The magnetostrictive/piezoelectric ME composite element comprises a magnetorestrictive multilayer deposited on a piezoelectric layer. The magnetorestrictive multilayer produces an in-plane uniaxial magnetic anisotropy (UMA). The UMA is a twofold UMA that exhibits a symmetric radiation pattern. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/656761 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0286 (20130101) Original (OR) Class Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/135 (20130101) H03H 9/175 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072521 | Dragic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois); Clemson University (Clemson, South Carolina) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); CLEMSON UNIVERSITY (Clemson, South Carolina) |
| INVENTOR(S) | Peter D. Dragic (Champaign, Illinois); John Ballato (Clemson, South Carolina); Thomas W. Hawkins (Clemson, South Carolina) |
| ABSTRACT | A fiber includes a core and cladding, both of which may have temperature dependent indices of refraction. The materials and size of the core and cladding may be selected such that as the temperature of the core and/or cladding is heated above room temperature, the fiber transitions from supporting multimode optical waveguiding to supporting single mode waveguiding. |
| FILED | Friday, October 23, 2020 |
| APPL NO | 17/079090 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/0003 (20130101) Original (OR) Class G02B 6/02004 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/1601 (20130101) H01S 3/06716 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072531 | Su et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Analog Photonics LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | Analog Photonics LLC (Boston, Massachusetts) |
| INVENTOR(S) | Zhan Su (Boston, Massachusetts); Erman Timurdogan (Somerville, Massachusetts); Michael Robert Watts (Hingham, Massachusetts) |
| ABSTRACT | A polarization rotator structure includes: a first core structure formed at a first layer, extending from the first end to a second end, and a second core structure formed at a second layer that is at a different depth than the first layer and formed in proximity to the first core structure. The first core structure and the second core structure provide mode hybridization between at least two orthogonally polarized waveguide modes of the PRS. An optical splitter structure is optically coupled at a first end to the second end of the PRS, and optically coupled at a second end to at least two optical waveguides, and includes: a first core structure that is contiguous with at least one of the first or second core structures of the PRS, and a second core structure that is separate from both of the first and second core structures of the PRS. |
| FILED | Wednesday, June 29, 2022 |
| APPL NO | 17/852769 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/14 (20130101) G02B 6/125 (20130101) G02B 6/126 (20130101) G02B 6/276 (20130101) G02B 6/1228 (20130101) G02B 6/2726 (20130101) G02B 6/2733 (20130101) G02B 6/2766 (20130101) Original (OR) Class G02B 6/2773 (20130101) G02B 6/12002 (20130101) G02B 6/12004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072623 | Shi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Phase Sensitive Innovations, Inc. (Newark, Delaware) |
| ASSIGNEE(S) | Phase Sensitive Innovations, Inc. (Newark, Delaware) |
| INVENTOR(S) | Shouyuan Shi (Newark, Delaware); Dennis Prather (Newark, Delaware); Peng Yao (Newark, Delaware); Janusz Murakowski (Bear, Delaware) |
| ABSTRACT | This disclosure is directed to two-dimensional conformal optically-fed phased arrays and methods for manufacturing the same. The method includes providing a wafer substrate, depositing a first cladding layer on the wafer substrate, and depositing a core layer on the first cladding layer. The method further includes photolithographically patterning the core layer to provide a plurality of optical waveguide cores, and depositing a second cladding layer on the core layer to cover the plurality of optical waveguide cores to provide a plurality of optical waveguides. In addition, the method includes forming a plurality of antennas on the second cladding layer, each antenna of the plurality of antennas located near a termination of a corresponding optical waveguide of the plurality of optical waveguides, and providing a plurality of photodiodes on the second cladding layer, each photodiode of the plurality of photodiodes connected to a corresponding antenna. |
| FILED | Wednesday, January 27, 2021 |
| APPL NO | 17/159628 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0005 (20130101) Original (OR) Class G03F 7/16 (20130101) Antennas, i.e Radio Aerials H01Q 1/38 (20130101) H01Q 1/2283 (20130101) H01Q 3/2676 (20130101) H01Q 21/062 (20130101) H01Q 21/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073149 | Cai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas) |
| INVENTOR(S) | Wei Cai (Dallas, Texas); Bo Wang (Dallas, Texas); Wenzhong Zhang (Dallas, Texas) |
| ABSTRACT | Systems and methods for computing interactions of charge sources embedded in three dimensional (3D) layered media. At least one of the methods includes decomposing the Green's function representing the potential caused by a charge source into a free space component and a plurality of reaction components; generating, for each reaction component of the plurality of reaction components, a multipole expansion (ME) operator and a multipole to local (M2L) translation operator; performing, for each reaction component of the plurality of reaction components, a convergence analysis of an ME of that reaction component; defining, for each reaction component, polarization charge sources based on the convergence analysis and combining the polarization charges sources with the charge sources; and computing, using a fast multipole method (FMM), interactions of the charge sources based on the polarization charge sources, the ME operators, and the M2L translation operators. |
| FILED | Tuesday, June 08, 2021 |
| APPL NO | 17/341596 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) G06F 30/10 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073559 | Asiedu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Mercy Asiedu (Durham, North Carolina); Nirmala Ramanujam (Durham, North Carolina); Guillermo Sapiro (Durham, North Carolina) |
| ABSTRACT | A method for automated detection of cervical pre-cancer includes: providing at least one cervigram; pre-processing the at least one cervigram; extracting features from the at least one pre-processed cervigram; and classifying the at least one cervigram as negative or positive for cervical pre-cancer based on the extracted features. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/282093 |
| ART UNIT | 2635 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/000094 (20220201) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/136 (20170101) G06T 7/168 (20170101) G06T 2207/20024 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20132 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073560 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia); University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Sepideh Azarianpour Esfahani (Cleveland Heights, Ohio); Haider Mahdi (Wexford, Pennsylvania) |
| ABSTRACT | Various embodiments of the present disclosure are directed towards a method for generating a risk group classification for an African American (AA) patient. The method includes extracting a first plurality of architectural features from a digitized H&E slide image of the AA patient. A risk score for the AA patient is generated based on the first plurality of architectural features, where the risk score is prognostic of overall survival (OS) of the AA patient. The risk group classification is generated for the AA patient, where generating the risk group classification includes classifying the AA patient into either a high risk group or a low risk group based on the risk score, where the high risk group indicates the AA patient will die before a threshold date and the low risk group indicates the AA patient will die after or on the threshold date. |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/671882 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/30024 (20130101) G06T 2207/30096 (20130101) Image or Video Recognition or Understanding G06V 10/764 (20220101) G06V 10/774 (20220101) G06V 20/698 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073578 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas); Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Yicheng Wu (Houston, Texas); Vivek Boominathan (Houston, Texas); Huaijin Chen (Houston, Texas); Aswin C. Sankaranarayanan (Pittsburgh, Pennsylvania); Ashok Veeraraghavan (Houston, Texas) |
| ABSTRACT | A method for a passive single-viewpoint 3D imaging system comprises capturing an image from a camera having one or more phase masks. The method further includes using a reconstruction algorithm, for estimation of a 3D or depth image. |
| FILED | Wednesday, April 26, 2023 |
| APPL NO | 18/307387 |
| ART UNIT | 2482 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/55 (20170101) Original (OR) Class G06T 2200/08 (20130101) Pictorial Communication, e.g Television H04N 13/111 (20180501) H04N 13/122 (20180501) H04N 13/128 (20180501) H04N 13/229 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12074213 | Nuzzo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Ralph G. Nuzzo (Champaign, Illinois); John A. Rogers (Wilmette, Illinois); Etienne Menard (Voglans, France); Keon Jae Lee (Daejeon, South Korea); Dahl-Young Khang (Seoul, South Korea); Yugang Sun (Gladwyne, Pennsylvania); Matthew Meitl (Durham, North Carolina); Zhengtao Zhu (Rapid City, South Dakota) |
| ABSTRACT | The invention provides methods and devices for fabricating printable semiconductor elements and assembling printable semiconductor elements onto substrate surfaces. Methods, devices and device components of the present invention are capable of generating a wide range of flexible electronic and optoelectronic devices and arrays of devices on substrates comprising polymeric materials. The present invention also provides stretchable semiconductor structures and stretchable electronic devices capable of good performance in stretched configurations. |
| FILED | Thursday, June 24, 2021 |
| APPL NO | 17/357697 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/0185 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/308 (20130101) H01L 21/322 (20130101) H01L 21/02521 (20130101) H01L 21/02603 (20130101) H01L 21/02628 (20130101) H01L 21/6835 (20130101) H01L 23/02 (20130101) H01L 24/03 (20130101) H01L 24/05 (20130101) H01L 24/08 (20130101) H01L 24/29 (20130101) H01L 24/32 (20130101) H01L 24/80 (20130101) H01L 24/83 (20130101) H01L 24/94 (20130101) H01L 24/97 (20130101) H01L 25/0753 (20130101) H01L 27/1285 (20130101) H01L 27/1292 (20130101) H01L 29/04 (20130101) H01L 29/06 (20130101) H01L 29/12 (20130101) H01L 29/068 (20130101) H01L 29/76 (20130101) Original (OR) Class H01L 29/0665 (20130101) H01L 29/0673 (20130101) H01L 29/0676 (20130101) H01L 29/78603 (20130101) H01L 29/78681 (20130101) H01L 29/78696 (20130101) H01L 31/0392 (20130101) H01L 31/1804 (20130101) H01L 31/1864 (20130101) H01L 31/1896 (20130101) H01L 31/03926 (20130101) H01L 33/007 (20130101) H01L 33/32 (20130101) H01L 33/0093 (20200501) H01L 2221/68368 (20130101) H01L 2221/68381 (20130101) H01L 2224/03 (20130101) H01L 2224/03 (20130101) H01L 2224/03 (20130101) H01L 2224/80 (20130101) H01L 2224/80 (20130101) H01L 2224/83 (20130101) H01L 2224/83 (20130101) H01L 2224/94 (20130101) H01L 2224/94 (20130101) H01L 2224/95 (20130101) H01L 2224/97 (20130101) H01L 2224/97 (20130101) H01L 2224/97 (20130101) H01L 2224/0332 (20130101) H01L 2224/0332 (20130101) H01L 2224/0345 (20130101) H01L 2224/0362 (20130101) H01L 2224/2919 (20130101) H01L 2224/2919 (20130101) H01L 2224/03614 (20130101) H01L 2224/05073 (20130101) H01L 2224/05073 (20130101) H01L 2224/05082 (20130101) H01L 2224/05082 (20130101) H01L 2224/05124 (20130101) H01L 2224/05124 (20130101) H01L 2224/05144 (20130101) H01L 2224/05144 (20130101) H01L 2224/05144 (20130101) H01L 2224/05155 (20130101) H01L 2224/05155 (20130101) H01L 2224/05155 (20130101) H01L 2224/05166 (20130101) H01L 2224/05166 (20130101) H01L 2224/05166 (20130101) H01L 2224/05552 (20130101) H01L 2224/05552 (20130101) H01L 2224/05553 (20130101) H01L 2224/05553 (20130101) H01L 2224/05554 (20130101) H01L 2224/05554 (20130101) H01L 2224/05555 (20130101) H01L 2224/05555 (20130101) H01L 2224/05644 (20130101) H01L 2224/05644 (20130101) H01L 2224/05644 (20130101) H01L 2224/05644 (20130101) H01L 2224/05666 (20130101) H01L 2224/05666 (20130101) H01L 2224/08225 (20130101) H01L 2224/8385 (20130101) H01L 2224/9202 (20130101) H01L 2224/9202 (20130101) H01L 2224/32225 (20130101) H01L 2224/32225 (20130101) H01L 2224/80006 (20130101) H01L 2224/80121 (20130101) H01L 2224/80121 (20130101) H01L 2224/80862 (20130101) H01L 2224/80895 (20130101) H01L 2224/83005 (20130101) H01L 2224/83121 (20130101) H01L 2224/83121 (20130101) H01L 2224/83192 (20130101) H01L 2224/83192 (20130101) H01L 2224/83193 (20130101) H01L 2224/83862 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00012 (20130101) H01L 2924/00012 (20130101) H01L 2924/00012 (20130101) H01L 2924/00012 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/14 (20130101) H01L 2924/14 (20130101) H01L 2924/0665 (20130101) H01L 2924/0665 (20130101) H01L 2924/01032 (20130101) H01L 2924/01032 (20130101) H01L 2924/01032 (20130101) H01L 2924/1305 (20130101) H01L 2924/1305 (20130101) H01L 2924/1306 (20130101) H01L 2924/1306 (20130101) H01L 2924/1461 (20130101) H01L 2924/1461 (20130101) H01L 2924/1579 (20130101) H01L 2924/10253 (20130101) H01L 2924/10329 (20130101) H01L 2924/12032 (20130101) H01L 2924/12032 (20130101) H01L 2924/12036 (20130101) H01L 2924/12036 (20130101) H01L 2924/12041 (20130101) H01L 2924/12042 (20130101) H01L 2924/12042 (20130101) H01L 2924/12043 (20130101) H01L 2924/12043 (20130101) H01L 2924/12044 (20130101) H01L 2924/12044 (20130101) H01L 2924/13055 (20130101) H01L 2924/13055 (20130101) H01L 2924/13063 (20130101) H01L 2924/13063 (20130101) H01L 2924/13091 (20130101) H01L 2924/13091 (20130101) H01L 2924/15159 (20130101) H01L 2924/15162 (20130101) H01L 2924/15788 (20130101) H01L 2924/15788 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/547 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/707 (20130101) Y10S 977/724 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12074228 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
| INVENTOR(S) | Sang M. Han (Albuquerque, New Mexico); Omar Abudayyeh (Albuquerque, New Mexico); David Wilt (Albuquerque, New Mexico); Nathan Gapp (Albuquerque, New Mexico) |
| ABSTRACT | A solar cell structure is disclosed that includes a first metal layer, formed over predefined portions of a sun-exposed major surface of a semiconductor structure, that form electrical gridlines of the solar cell; a network of carbon nanotubes formed over the first metal layer; and a second metal layer formed onto the network of carbon nanotubes, wherein the second metal layer infiltrates the network of carbon nanotubes to connect with the first metal layer to form a first metal matrix composite comprising a metal matrix and a carbon nanotube reinforcement, wherein the second metal layer is an electrically conductive layer in which the carbon nanotube reinforcement is embedded in and bonded to the metal matrix, and the first metal matrix composite provides enhanced mechanical support as well as enhanced or equal electrical conductivity for the electrical contacts against applied mechanical stressors to the electrical contacts. |
| FILED | Monday, June 27, 2022 |
| APPL NO | 17/850045 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/158 (20170801) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/05 (20130101) H01L 31/073 (20130101) H01L 31/0201 (20130101) H01L 31/02008 (20130101) Original (OR) Class H01L 31/022425 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/44 (20141201) Organic electric solid-state devices H10K 30/821 (20230201) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/75 (20130101) Y10S 977/89 (20130101) Y10S 977/752 (20130101) Y10S 977/842 (20130101) Y10S 977/891 (20130101) Y10S 977/901 (20130101) Y10S 977/948 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12074609 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Zhi Yang (Minneapolis, Minnesota); Anh Tuan Nguyen (Minneapolis, Minnesota); Diu Khue Luu (Minneapolis, Minnesota); Jian Xu (Minneapolis, Minnesota) |
| ABSTRACT | A digital-to-analog converter device including a set of components, each component included in the set of components including a number of unit cells, each unit cell being associated with a unit cell size indicating manufacturing specifications of the unit cell is provided by the present disclosure. The digital-to-analog converter device further includes a plurality of switches, each switch included in the plurality of switches being coupled to a component included in the set of components, and an output electrode coupled to the plurality of switches. The digital-to-analog converter device is configured to output an output signal at the output electrode. A first unit cell size associated with a first unit cell included in the set of components is different than a second unit cell size associated with a second unit cell included in the set of components. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/687765 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/007 (20130101) H03M 1/46 (20130101) Original (OR) Class H03M 1/447 (20130101) H03M 1/802 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12075185 | Caulfield et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cyan Systems (Santa Barbara, California) |
| ASSIGNEE(S) | Cyan Systems (Santa Barbara, California) |
| INVENTOR(S) | John Caulfield (Santa Barbara, California); Jon Paul Curzan (Arroyo Grande, California) |
| ABSTRACT | A method that can detect targets is described. The method includes setting an integration time for each of a plurality of readout circuits based on a speed of the target. The readout circuits are configured to read pixels in an image detector. The pixels have a pitch of less than ten micrometers. The integration time is not more than five hundred microseconds and corresponds to a subframe of a fast frame image. The method also includes performing integrations of each readout circuit based on the integration time. Thus, a plurality of subframes are provided. A number of the subframes are averaged to provide the fast frame image. |
| FILED | Tuesday, March 07, 2023 |
| APPL NO | 18/118691 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/248 (20170101) G06T 2207/10048 (20130101) G06T 2207/20212 (20130101) Image or Video Recognition or Understanding G06V 10/255 (20220101) Pictorial Communication, e.g Television H04N 5/33 (20130101) Original (OR) Class H04N 25/53 (20230101) H04N 25/75 (20230101) H04N 25/533 (20230101) H04N 25/587 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12075555 | Kobernik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SHINE Technologies, LLC (Janesville, Wisconsin) |
| ASSIGNEE(S) | SHINE Technologies, LLC (Janesville, Wisconsin) |
| INVENTOR(S) | Arne Kobernik (Monona, Wisconsin); Carl Sherven (Monona, Wisconsin); Casey Lamers (Monona, Wisconsin); Chris Seyfert (Monona, Wisconsin); Evan Sengbusch (Monona, Wisconsin); Gabriel Becerra (Monona, Wisconsin); Jin Lee (Monona, Wisconsin); Logan Campbell (Monona, Wisconsin); Mark Thomas (Monona, Wisconsin); Michael Taylor (Monona, Wisconsin); Preston Barrows (Monona, Wisconsin); Ross Radel (Monona, Wisconsin); Tye Gribb (Monona, Wisconsin) |
| ABSTRACT | Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes. |
| FILED | Thursday, June 01, 2023 |
| APPL NO | 18/204659 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/08 (20130101) H01J 37/32082 (20130101) H01J 41/04 (20130101) H01J 41/14 (20130101) Spark Gaps; Overvoltage Arresters Using Spark Gaps; Sparking Plugs; Corona Devices; Generating Ions to be Introduced into Non-enclosed Gases H01T 23/00 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 31/26 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) H05H 1/54 (20130101) H05H 1/4622 (20210501) H05H 3/06 (20130101) H05H 5/04 (20130101) H05H 6/00 (20130101) H05H 7/22 (20130101) Original (OR) Class H05H 9/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12070241 | Franco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Walfre Franco (Westborough, Massachusetts); Esmeralda Ibarra-Silva (Boston, Massachusetts); William A. Farinelli (Boston, Massachusetts); Joshua Tam (Boston, Massachusetts); R. Rox Anderson (Boston, Massachusetts); Lynn Drake (Boston, Massachusetts) |
| ABSTRACT | Systems and methods are provided for performing a hair transplant using a hair transplant device. The hair transplant device comprises a coring needle, a splitting needle, a housing, and a user interface. The coring needle forms a coring lumen configured to extract a hair follicle from a donor site. The splitting needle is configured to create an opening in a recipient site. The housing at least partially surrounds one of the coring needle and the splitting needle. The user interface extends from the housing and is movable relative to the coring needle to push the hair follicle from the coring lumen into the opening in the recipient site formed by the splitting needle. |
| FILED | Monday, July 16, 2018 |
| APPL NO | 16/629657 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/32053 (20130101) Original (OR) Class A61B 2017/00367 (20130101) A61B 2017/00752 (20130101) A61B 2017/00969 (20130101) A61B 2017/3454 (20130101) A61B 2017/320064 (20130101) A61B 2090/034 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070282 | Farritor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Shane Farritor (Lincoln, Nebraska); Tom Frederick (Gretna, Nebraska); Kearney Lackas (Lincoln, Nebraska); Joe Bartels (Pittsburgh, Pennsylvania); Jacob Greenburg (Lincoln, Nebraska) |
| ABSTRACT | The various embodiments herein relate to robotic surgical systems and devices that use force and/or torque sensors to measure forces applied at various components of the system or device. Certain implementations include robotic surgical devices having one or more force/torque sensors that detect or measure one or more forces applied at or on one or more arms. Other embodiments relate to systems having a robotic surgical device that has one or more sensors and an external controller that has one or more motors such that the sensors transmit information that is used at the controller to actuate the motors to provide haptic feedback to a user. |
| FILED | Tuesday, July 07, 2020 |
| APPL NO | 16/922560 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Original (OR) Class A61B 34/76 (20160201) A61B 2090/064 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/1602 (20130101) B25J 9/1633 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/36432 (20130101) G05B 2219/39181 (20130101) G05B 2219/39194 (20130101) G05B 2219/39321 (20130101) G05B 2219/40619 (20130101) G05B 2219/45117 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/27 (20130101) Y10S 901/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070445 | Blackwell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Helen Elizabeth Blackwell (Middleton, Wisconsin); Thomas John Polaske (Madison, Wisconsin); David Lynn (Middleton, Wisconsin); Curran Gahan (Madison, Wisconsin); Kayleigh E. Nyffeler Bucci (Madison, Wisconsin) |
| ABSTRACT | The present technology provides a system for monitoring quorum-sensing in bacteria comprising bacteria that release at least one membrane-lytic toxin when the bacteria are at a quorum-sensing density; synthetic lipid vesicles comprising an environmentally sensitive indicator, wherein the synthetic lipid vesicles release the environmentally sensitive dye in the presence of an effective amount of the membrane-lytic toxins; and a growth medium; wherein the bacteria and synthetic lipid vesicles are in contact with the growth medium. Methods using the system and compounds discovered with the system (e.g., compounds of Formulas I and II) are also disclosed. |
| FILED | Friday, August 26, 2022 |
| APPL NO | 17/896558 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/381 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070748 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | Thomas W. Chen (Fort Collins, Colorado); Daniel S. Ball (Fort Collins, Colorado); Caleb R. Begly (Colorado Springs, Colorado) |
| ABSTRACT | A well plate for measuring an analyte in a sample is disclosed. The well plate includes at least a first, a second, and a third electrode. The first electrode has a higher sensitivity to a first analyte than the second and third electrodes. The second electrode has a higher sensitivity to a second analyte than the first and third electrodes. |
| FILED | Saturday, April 11, 2020 |
| APPL NO | 16/846330 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5025 (20130101) B01L 3/5085 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 2200/027 (20130101) B01L 2300/0645 (20130101) B01L 2300/0825 (20130101) B01L 2300/0829 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070861 | Torabi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | 3DEO, Inc. (Torrance, California) |
| ASSIGNEE(S) | 3DEO, Inc. (Torrance, California) |
| INVENTOR(S) | Payman Torabi (Los Angeles, California); Matthew Petros (Los Angeles, California); Zhuofeng Zhang (Los Angeles, California) |
| ABSTRACT | The present disclosure provides systems and methods for training a robot. The systems and methods may provide a robotic system. The robotic system may comprise a trainable robot and a sensor. The sensor may be attached to at least one physical tool. The method may comprise using the sensor to capture movement from a user operating the at least one physical tool. The method may include using at least the movement captured to train the robot, such that upon training, the robot may be trained to perform at least the movement. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/175510 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/163 (20130101) Original (OR) Class B25J 9/1664 (20130101) B25J 9/1697 (20130101) B25J 13/089 (20130101) B25J 15/0019 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/227 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071386 | Voutchkova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia) |
| INVENTOR(S) | Adelina M. Voutchkova (Washington, District of Columbia); Diana Ainembabazi (Washington, District of Columbia); Darren Dolan (Washington, District of Columbia); Jonathan Horlyck (Washington, District of Columbia) |
| ABSTRACT | The present disclosure relates to a process for preparing long-chain alkanes and alkenes from alcohols, aldehydes, or both. The process proceeds via acceptorless dehydrogenation and decarbonylative coupling using a supported catalyst. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/168738 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/44 (20130101) B01J 35/40 (20240101) Acyclic or Carbocyclic Compounds C07C 1/24 (20130101) Original (OR) Class C07C 2523/44 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/04 (20130101) C10L 2200/0469 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071445 | Hazari et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Nilay Hazari (New Haven, Connecticut); Patrick Melvin (New Haven, Connecticut); Damian Hruszkewycz (New Haven, Connecticut) |
| ABSTRACT | The present invention provides novel transition-metal precatalysts that are useful in preparing active coupling catalysts. In certain embodiments, the precatalysts of the invention are air-stable and moisture-stable. The present invention further provides methods of making and using the precatalysts of the invention. |
| FILED | Monday, February 27, 2023 |
| APPL NO | 18/175357 |
| ART UNIT | 1738 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 2602/10 (20170501) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 17/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071489 | Luo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Dan Luo (Ithaca, New York); Dong Wang (Ithaca, New York) |
| ABSTRACT | Crosslinked nucleotide polymers. A crosslinked nucleotide polymer may be formed by reaction of a biomass comprising DNA and/or RNA with one or more crosslinker(s). A crosslinked nucleotide polymers may be formed by a crosslinking reaction including an aza-Michael addition reaction. Crosslinked nucleotide polymers may be present in various forms and compositions and form various articles of manufacture. Crosslinked nucleotide polymers may be used in therapeutic methods, coating methods, and cell-free protein production methods. |
| FILED | Wednesday, May 12, 2021 |
| APPL NO | 17/318845 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Separation B01D 11/0288 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0003 (20130101) Original (OR) Class C08B 37/003 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/09 (20130101) C08J 2367/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071515 | Alim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Marvin D. Alim (Kirkland, Washington); Christopher N. Bowman (Boulder, Colorado); Sudheendran Mavila (Boulder, Colorado); Robert R. McLeod (Boulder, Colorado) |
| ABSTRACT | The present invention, in one aspect, relates to monomers and photopolymers that exhibit a high refractive index. The photopolymers of the invention have properties suitable for fabricating holographic optical elements (HOEs). |
| FILED | Monday, June 10, 2019 |
| APPL NO | 16/972884 |
| ART UNIT | 1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/50 (20130101) C08F 20/38 (20130101) C08F 28/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 75/02 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 5/32 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/001 (20130101) G03F 7/004 (20130101) Holographic Processes or Apparatus G03H 1/024 (20130101) G03H 2260/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071550 | Harris et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Tequila A. L. Harris (Atlanta, Georgia); Kyriaki Kalaitzidou (Atlanta, Georgia); Yuhan Xiao (Atlanta, Georgia); Donggang Yao (Atlanta, Georgia) |
| ABSTRACT | In a method of depositing a fibroin structure, a fibroin ink is generated. The fibroin ink is aerosol jet printed onto a substrate. To prepare the ink, a plurality of biologically-generated silk cocoons are each cut into at least two pieces of raw silk and are degummed to remove sericin, leaving fibroin fibers. The fibroin fibers are dissolved into a lithium bromide solution. The salt is removed by placing the fibroin/salt solution in a dialysis membrane tube and submerging it in deionized water. The fibroin solution is centrifuged to remove impurities therefrom, leaving fibroin ink. The fibroin ink is atomized into a fibroin ink aerosol, which is directed to a print nozzle. A focusing gas sheath is directed around the print nozzle to deposit fibroin onto a surface. |
| FILED | Wednesday, February 17, 2021 |
| APPL NO | 17/177631 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/00 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) B05D 1/12 (20130101) Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/215 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/08 (20130101) Original (OR) Class C09D 11/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071610 | Fan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Zhonghui Hugh Fan (Gainesville, Florida); Xiao Jiang (Gainesville, Florida); Trevor B. Tilly (Gainesville, Florida); John Lednicky (Gainesville, Florida); Chang-Yu Wu (Gainesville, Florida) |
| ABSTRACT | An apparatus and method are provided for performing detection of microorganisms (e.g., viruses) with high sensitivity. The apparatus and method are well suited for point-of-care (POC) testing in resource-limited regions and are capable of being operated with very little manual intervention and without the need for lab equipment. A variety of viruses can be detected with high sensitivity, including, for example, coronaviruses, Zika virus and flu viruses. |
| FILED | Monday, January 04, 2021 |
| APPL NO | 17/140696 |
| ART UNIT | 1758 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/527 (20130101) B01L 2200/025 (20130101) B01L 2200/026 (20130101) B01L 2200/028 (20130101) B01L 2400/0616 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/44 (20130101) C12M 41/46 (20130101) Original (OR) Class C12M 41/48 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56916 (20130101) G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071696 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Shaowei Chen (Santa Cruz, California); Forrest Nichols (Santa Cruz, California) |
| ABSTRACT | The catalyst composition includes graphitic carbon nitride and a plurality of platinum oxide nanoparticles disposed on the graphitic carbon nitride. |
| FILED | Monday, August 14, 2023 |
| APPL NO | 18/449110 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/052 (20210101) Original (OR) Class C25B 11/067 (20210101) C25B 11/075 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072283 | Hendon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Christine Hendon (Bronx, New York); Rajinder Singh-Moon (Mastic, New York); James McLean (New York, New York); Soo Young Park (Seoul, South Korea) |
| ABSTRACT | An exemplary catheter can be provided, which can include, for example a source fiber(s) configured to (i) receive a near infrared spectroscopic (NIRS) radiation, and (ii) provide the NIRS radiation to a portion(s) of a sample(s), a detection fiber(s) configured to receive a return radiation from the sample(s) that can be based on the NIRS radiation that was provided to the portion(s) of the sample(s), and an ablation electrode(s) configured to ablate the sample(s) based on the return radiation. The source fiber(s), the detection fiber(s), and the ablation electrode(s) can be integrated into the single sheath. The ablation electrode(s) can be a radiofrequency ablation electrode. |
| FILED | Friday, June 19, 2020 |
| APPL NO | 16/906429 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/0086 (20130101) A61B 18/1492 (20130101) A61B 2018/00577 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/359 (20130101) G01N 21/474 (20130101) G01N 21/3563 (20130101) Original (OR) Class G01N 2021/4709 (20130101) G01N 2021/4745 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072290 | Angel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Stanley Michael Angel (Columbia, South Carolina); Jerry Chance Carter (Livermore, California) |
| ABSTRACT | A hyperspectral imaging apparatus based on a monolithic or free space optical spatial heterodyne spectrometer (SHS) design, array detector, electromagnetic radiation source, and optical collection element is described. The apparatus enables the simultaneous acquisition of spatially isolated Fizeau fringe patterns, each having an encoded light product that is decoded to produce a spectral fingerprint of the interrogated object. Features specific to the SHS, such as a large entrance aperture, large acceptance angle, and no moving parts, enable a variety of optical collection schemes including lens arrays, solid-core and hollow core waveguides, and others. In one example, a microlens array (MLA) is configured with the hyperspectral imaging apparatus to simultaneously image many hundred spatially isolated Fizeau fringe patterns while interrogating an object using an electromagnetic radiation source. Each Fizeau fringe pattern recorded by the array detector is decoded to produce a full Raman or laser-induced breakdown spectroscopy (LIBS) spectrum. Compared to prior art, the hyperspectral imaging apparatus overcomes the primary limitations of needing to trade time resolution for both spectral and spatial data density because the imaging apparatus simultaneously acquires both spectral and special information. Based on the selection and configuration of diffraction gratings, the grating aperture size, Littrow wavelength (i.e., heterodyne wavelength), and optical collection configuration, the apparatus can be tailored to produced low or high spectral resolution with a spectral bandpass that covers a portion or the entire Raman spectral range (up to 4200 cm−1) and for LIBS as well. |
| FILED | Friday, September 11, 2020 |
| APPL NO | 17/772265 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 2201/0633 (20130101) G01N 2201/0635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072379 | Chakrabarty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Krishnendu Chakrabarty (Durham, North Carolina); Jonti Talukdar (Durham, North Carolina); Arjun Chaudhuri (Durham, North Carolina) |
| ABSTRACT | An integrated circuit (IC) protection circuit can include a reconfigurable block that receives a seed value from a tamper-proof memory and generates a dynamic key; an authentication block that receives the dynamic key from the reconfigurable block and taint bits from a scan chain to generate an authentication signature; and an encryptor that encrypts a test pattern response on the scan chain if a mismatch is found between the authentication signature and a test pattern embedded signature. |
| FILED | Monday, March 14, 2022 |
| APPL NO | 17/693942 |
| ART UNIT | 2443 — Computer Networks |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/3177 (20130101) Original (OR) Class G01R 31/31703 (20130101) Electric Digital Data Processing G06F 11/263 (20130101) G06F 2201/83 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072481 | Dickensheets et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MONTANA STATE UNIVERSITY (Bozeman, Montana); MEMORIAL SLOAN-KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MONTANA STATE UNIVERSITY (Bozeman, Montana); MEMORIAL SLOAN-KETTERING CANCER (New York, New York) |
| INVENTOR(S) | David Dickensheets (Bozeman, Montana); Milind Rajadhyaksha (New York, New York) |
| ABSTRACT | A device for viewing a target, the device including a housing, an objective lens positioned within the housing, where the objective lens has a first lens group including at least a first lens and a second lens group including at least a second lens, the first lens positioned closer to the target than the second lens, and a camera positioned within the objective lens between the first lens and the second lens, where the camera is configured to provide images of the target located near a focal point of the objective lens, and wherein the arrangement of the first lens, the second lens, and the camera provides for simultaneous capture of a first image of a surface of the target and a second image of a sub-surface cellular structure of the target. |
| FILED | Monday, April 11, 2022 |
| APPL NO | 17/717774 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0068 (20130101) A61B 5/0075 (20130101) A61B 5/0077 (20130101) A61B 5/444 (20130101) Optical Elements, Systems, or Apparatus G02B 21/02 (20130101) G02B 21/06 (20130101) G02B 21/0008 (20130101) G02B 21/0028 (20130101) G02B 21/0036 (20130101) G02B 21/361 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073149 | Cai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas) |
| INVENTOR(S) | Wei Cai (Dallas, Texas); Bo Wang (Dallas, Texas); Wenzhong Zhang (Dallas, Texas) |
| ABSTRACT | Systems and methods for computing interactions of charge sources embedded in three dimensional (3D) layered media. At least one of the methods includes decomposing the Green's function representing the potential caused by a charge source into a free space component and a plurality of reaction components; generating, for each reaction component of the plurality of reaction components, a multipole expansion (ME) operator and a multipole to local (M2L) translation operator; performing, for each reaction component of the plurality of reaction components, a convergence analysis of an ME of that reaction component; defining, for each reaction component, polarization charge sources based on the convergence analysis and combining the polarization charges sources with the charge sources; and computing, using a fast multipole method (FMM), interactions of the charge sources based on the polarization charge sources, the ME operators, and the M2L translation operators. |
| FILED | Tuesday, June 08, 2021 |
| APPL NO | 17/341596 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) G06F 30/10 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073161 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| INVENTOR(S) | Fei Wang (Knoxville, Tennessee); Leon M. Tolbert (Knoxville, Tennessee); Yiwei Ma (Knoxville, Tennessee); Kevin Louis Tomsovic (Knoxville, Tennessee); Kai Sun (Knoxville, Tennessee); Shuoting Zhang (Knoxville, Tennessee); Jingxin Wang (Knoxville, Tennessee); Bo Liu (Knoxville, Tennessee) |
| ABSTRACT | A system includes a controller that is configured to generate a node control signal and a plurality of switch control signals, a plurality of programmable emulators, each of the plurality of programmable emulators being configurable as one of a plurality of node types responsive to the node control signal, and a plurality of switches that are programmable to couple ones of the plurality of programmable emulators to each other responsive to the plurality of switch control signals. |
| FILED | Monday, April 19, 2021 |
| APPL NO | 17/234230 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/041 (20130101) Electric Digital Data Processing G06F 30/367 (20200101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/00 (20130101) H02J 3/36 (20130101) H02J 3/38 (20130101) H02J 2203/20 (20200101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/537 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073306 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The George Washington University (Washington, District of Columbia) |
| ASSIGNEE(S) | THE GEORGE WASHINGTON UNIVERSITY (Washington, District of Columbia) |
| INVENTOR(S) | Jiajun Li (Arlington, Virginia); Ahmed Louri (Vienna, Virginia) |
| ABSTRACT | Systems and methods are disclosed for a centrosymmetric convolutional neural network (CSCNN), an algorithm/hardware co-design framework for CNN compression and acceleration that mitigates the effects of computational irregularity and effectively exploits computational reuse and sparsity for increased performance and energy efficiency. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/551967 |
| ART UNIT | 2692 — Selective Visual Display Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 7/5443 (20130101) Computer Systems Based on Specific Computational Models G06N 3/045 (20230101) Original (OR) Class G06N 3/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073559 | Asiedu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Mercy Asiedu (Durham, North Carolina); Nirmala Ramanujam (Durham, North Carolina); Guillermo Sapiro (Durham, North Carolina) |
| ABSTRACT | A method for automated detection of cervical pre-cancer includes: providing at least one cervigram; pre-processing the at least one cervigram; extracting features from the at least one pre-processed cervigram; and classifying the at least one cervigram as negative or positive for cervical pre-cancer based on the extracted features. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/282093 |
| ART UNIT | 2635 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/000094 (20220201) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/136 (20170101) G06T 7/168 (20170101) G06T 2207/20024 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20132 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073578 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas); Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Yicheng Wu (Houston, Texas); Vivek Boominathan (Houston, Texas); Huaijin Chen (Houston, Texas); Aswin C. Sankaranarayanan (Pittsburgh, Pennsylvania); Ashok Veeraraghavan (Houston, Texas) |
| ABSTRACT | A method for a passive single-viewpoint 3D imaging system comprises capturing an image from a camera having one or more phase masks. The method further includes using a reconstruction algorithm, for estimation of a 3D or depth image. |
| FILED | Wednesday, April 26, 2023 |
| APPL NO | 18/307387 |
| ART UNIT | 2482 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/55 (20170101) Original (OR) Class G06T 2200/08 (20130101) Pictorial Communication, e.g Television H04N 13/111 (20180501) H04N 13/122 (20180501) H04N 13/128 (20180501) H04N 13/229 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12074235 | Evans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Paul Gregory Evans (Madison, Wisconsin); Thomas Francis Kuech (Madison, Wisconsin); Donald E. Savage (Madison, Wisconsin); Yajin Chen (Madison, Wisconsin); Samuel Marks (Madison, Wisconsin) |
| ABSTRACT | Transparent, electrically conductive vanadium oxide-based perovskite films and methods of making the vanadium oxide-based perovskite films are provided. Transparent conducting vanadate perovskites are made by forming a layer of amorphous vanadate perovskite precursor around a plurality of nanoscale, crystalline, perovskite oxide seeds and heating the layer of amorphous vanadate perovskite precursor at a temperature that favors lateral vanadate perovskite crystal growth from the perovskite oxide seeds over homogeneous crystal nucleation within the layer of amorphous vanadate perovskite precursor material. The crystallization processes can form the desired vanadate perovskite phase directly or via a transformation in a controlled gas environment from an initial crystallized vanadate perovskite phase that has a higher oxidation state. |
| FILED | Wednesday, September 09, 2020 |
| APPL NO | 17/015428 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 31/02 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/34 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/35 (20130101) C23C 14/088 (20130101) C23C 14/5806 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 28/02 (20130101) C30B 29/30 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/085 (20130101) H01L 31/0232 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12074302 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| INVENTOR(S) | Yan Wang (Acton, Massachusetts); Eric Gratz (Westborough, Massachusetts); Qina Sa (Westborough, Massachusetts); Zhangfeng Zheng (Westborough, Massachusetts); Joseph Heelan (Woodstock, Connecticut); Kee-Chan Kim (Westborough, Massachusetts) |
| ABSTRACT | Cathode material from exhausted lithium ion batteries are dissolved in a solution for extracting the useful elements Co (cobalt), Ni (nickel), Al (Aluminum) and Mn (manganese) to produce active cathode materials for new batteries. The solution includes compounds of desirable materials such as cobalt, nickel, aluminum and manganese dissolved as compounds from the exhausted cathode material of spent cells. Depending on a desired proportion, or ratio, of the desired materials, raw materials are added to the solution to achieve the desired ratio of the commingled compounds for the recycled cathode material for new cells. The desired materials precipitate out of solution without extensive heating or separation of the desired materials into individual compounds or elements. The resulting active cathode material has the predetermined ratio for use in new cells, and avoids high heat typically required to separate the useful elements because the desired materials remain commingled in solution. |
| FILED | Wednesday, June 15, 2022 |
| APPL NO | 17/841152 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 1/24 (20130101) C22B 7/007 (20130101) C22B 23/043 (20130101) C22B 23/0423 (20130101) C22B 23/0438 (20130101) C22B 26/22 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12074609 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Zhi Yang (Minneapolis, Minnesota); Anh Tuan Nguyen (Minneapolis, Minnesota); Diu Khue Luu (Minneapolis, Minnesota); Jian Xu (Minneapolis, Minnesota) |
| ABSTRACT | A digital-to-analog converter device including a set of components, each component included in the set of components including a number of unit cells, each unit cell being associated with a unit cell size indicating manufacturing specifications of the unit cell is provided by the present disclosure. The digital-to-analog converter device further includes a plurality of switches, each switch included in the plurality of switches being coupled to a component included in the set of components, and an output electrode coupled to the plurality of switches. The digital-to-analog converter device is configured to output an output signal at the output electrode. A first unit cell size associated with a first unit cell included in the set of components is different than a second unit cell size associated with a second unit cell included in the set of components. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/687765 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 1/007 (20130101) H03M 1/46 (20130101) Original (OR) Class H03M 1/447 (20130101) H03M 1/802 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12075564 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Chi Hwan Lee (West Lafayette, Indiana); Laurent Couetil (West Lafayette, Indiana); Tae Hoo Chang (Beavercreek, Ohio); Semih Akin (West Lafayette, Indiana); Martin Byung-Guk Jun (West Lafayette, Indiana) |
| ABSTRACT | Electronic textiles and methods of fabrication electronic textiles. Nanoparticles of a conductive material are sprayed along a conductive path into a fabric material so as to penetrate into the fabric. A layer of a second conductor material is coated over the nanoparticles along the conductive path. A layer of an insulator material is coated over the layer of the second conductor material so as to encapsulate the conductive path and form a trace. An electrode configured to contact a subject wearing the fabric material includes a layer of a third conductor material coated over the layer of the second conductor and electrically coupled with the conductive path. An electrical connector is secured to the fabric material and electrically coupled with the conductive path. The nanoparticles are sprayed onto the fabric material using a dual regime spray process implemented with a dual regime spray system. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/823021 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/27 (20210101) A61B 2503/40 (20130101) A61B 2562/0215 (20170801) A61B 2562/0285 (20130101) Treating Textile Materials Using Liquids, Gases or Vapours D06B 11/0059 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 11/65 (20130101) D06M 11/83 (20130101) D06M 15/693 (20130101) D06M 23/08 (20130101) D06M 2101/06 (20130101) D06M 2101/32 (20130101) D06M 2101/38 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2201/02 (20130101) D10B 2331/04 (20130101) D10B 2331/10 (20130101) D10B 2401/16 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 3/28 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/038 (20130101) Original (OR) Class H05K 1/092 (20130101) H05K 3/14 (20130101) H05K 2201/10151 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12070751 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Peter Wonhee Kim (Alameda, California); Anup K. Singh (Danville, California); Daniel J. Throckmorton (Tracy, California); James S. Brennan (Rodeo, California); Mark Richard Claudnic (Livermore, California) |
| ABSTRACT | A device for analyzing biological samples comprises first, second, third, and fourth layers. The first layer comprises a sample chamber in which a sample is positioned. The second layer comprises first, second, and third channels. A third, porous layer is positioned between the first layer and the second layer. A fourth layer composed of a substantially liquid-impermeable material is positioned between the second layer and the third layer. The fourth layer includes first and second pass-through channels that are aligned with the first and second channel, respectively. Fluids that flow in the first and second channels pass through the pass-through channels and diffuse into the sample chamber, establishing a chemical concentration gradient therein. A gas in the sample chamber can diffuse through the third and fourth layers and interact with a fluid flowing in the third channel, establishing a gas concentration gradient in the sample chamber. |
| FILED | Thursday, February 18, 2021 |
| APPL NO | 17/178709 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Original (OR) Class B01L 2200/0694 (20130101) B01L 2300/0883 (20130101) B01L 2300/0887 (20130101) B01L 2400/0472 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070793 | Carlson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Matthew D. Carlson (Albuquerque, New Mexico) |
| ABSTRACT | The casting material may be formed around the casting core using a variety of conventional casting techniques including direct liquid metal infiltration, pressure assisted casting, and centrifugal casting among others. |
| FILED | Thursday, September 03, 2020 |
| APPL NO | 17/011149 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Foundry Moulding B22C 1/14 (20130101) B22C 1/181 (20130101) B22C 9/10 (20130101) Original (OR) Class Casting of Metals; Casting of Other Substances by the Same Processes or Devices B22D 29/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070798 | Niebedim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Cajetan Ikenna Niebedim (Ames, Iowa); Abhishek Sarkar (Ames, Iowa); Matthew J. Kramer (Ankeny, Iowa); Thomas Lograsso (Ames, Iowa); Mark Christopher Haase (Cedar Park, Texas); Somashekara Adinarayanappa (Katnataka, India); Mariappan Parans Paranthaman (Knoxville, Tennessee) |
| ABSTRACT | Embodiments of the present invention provide an electromagnet alignment system for AM or 3D printing technology providing improved in-situ alignment of the magnetic particulate material as it is dispensed during deposition to form a 3D shape. In-situ alignment of the magnetic particulate material can be controlled to be unidirectional or multi-directional. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/300213 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/34 (20210101) Original (OR) Class B22F 12/53 (20210101) B22F 2202/05 (20130101) B22F 2302/25 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/00 (20141201) B33Y 70/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070817 | Penny et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ryan Wade Penny (Cambridge, Massachusetts); Anastasios John Hart (Waban, Massachusetts) |
| ABSTRACT | Systems, devices, and methods for additive manufacturing are provided that allow for components being manufactured to be assessed during the printing process. As a result, changes to a print plan can be considered, made, and implemented during the printing process. More particularly, in exemplary embodiments, a spectrometer is operated while a component is being printed to measure one or more parameters associated with one or more layers of the component being printed. The measured parameter(s) are then relied upon to determine if any changes are needed to the way printing is occurring, and if such changes are desirable, the system is able to implement such changes during the printing process. By way of non-limiting examples, printed material in one or more layers may be reheated to alter the printed component, such as to remove defects identified by the spectrometer data. A variety of systems, devices, and methods for performing real-time sensing and control of an additive manufacturing process are also provided. |
| FILED | Monday, November 28, 2022 |
| APPL NO | 18/070151 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/032 (20130101) B23K 26/70 (20151001) B23K 26/073 (20130101) B23K 26/342 (20151001) Original (OR) Class B23K 26/0622 (20151001) B23K 26/0626 (20130101) B23K 26/702 (20151001) B23K 26/0821 (20151001) B23K 31/125 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/30 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/94 (20130101) G01N 21/95 (20130101) G01N 21/8422 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071352 | Bayko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Dmitriy Pavlovich Bayko (Tucson, Arizona); Steven Kmiec (Ames, Iowa); Steve W. Martin (Ames, Iowa) |
| ABSTRACT | A method is provided for making high quality silicon sulfide having 4N (99.99% by weight) or better purity. |
| FILED | Tuesday, December 01, 2020 |
| APPL NO | 16/974249 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/00 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/61 (20130101) C01P 2006/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071455 | Hagen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan) |
| INVENTOR(S) | Andrew R. Hagen (Oakland, California); Cheryl A. Kerfeld (Walnut Creek, California); Nancy B. Sloan (Berkeley, California); Markus Sutter (Oakland, California); Bryan H. Ferlez (Haslett, Michigan) |
| ABSTRACT | The present invention provides for a fusion protein comprising (1) a bacterial microcompartment (BMC) shell protein comprising one or more subunit, and (2) a first component of a specific-binding pair, operably linked to the BMC shell protein such that the first component faces (i) a lumen (inside) side, or (ii) outside of a BMC shell formed incorporating the fusion protein and the fusion protein does not disrupt or prevent the folding of the BMC shell protein or the ability of the BMC shell protein to integrate with other BMC shell proteins into a BMC shell; wherein the first component is capable of forming a stable or irreversible interaction with a second component of the specific-binding pair. |
| FILED | Thursday, August 26, 2021 |
| APPL NO | 17/458131 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Separation B01D 15/363 (20130101) B01D 15/3804 (20130101) Peptides C07K 1/22 (20130101) C07K 14/195 (20130101) Original (OR) Class C07K 14/315 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071680 | Saw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Cheng K. Saw (Livermore, California); ByoungWoo William Choi (Livermore, California) |
| ABSTRACT | A product includes a ternary alloy consisting essentially of Sn4Li(4+x)Zn(8−x), where x=0 to <8. A method includes forming a ternary alloy using a mechanical alloying process. The ternary alloy consists essentially of Sn4Li(4+x)Zn(8−x), where x=0 to <8. |
| FILED | Friday, August 14, 2020 |
| APPL NO | 16/994324 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 1/0408 (20130101) C22C 24/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071697 | Budaragin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FCET, INC. (Alpharetta, Georgia); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | FCET, INC. (Roswell, Georgia); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Leonid V. Budaragin (Moscow, Russian Federation); Mark A. Deininger (Roswell, Georgia); Michael M. Pozvonkov (Cumming, Georgia); D. Morgan Spears, II (Atlanta, Georgia); Paul D. Fisher (Landis, North Carolina); Gerard M. Ludtka (Oak Ridge, Tennessee); Arvid E. Pasto (Sparks, Nevada) |
| ABSTRACT | Methods for forming a metal oxide electrolyte include applying a metal compound to a first material in powder form thereby forming a slurry, applying the slurry to an electrode, and converting at least some of the metal compound to form a metal oxide, thereby forming the metal oxide electrolyte on the electrode. Unexpectedly, the metal oxide electrolyte may have an ionic conductivity greater than the bulk ionic conductivity of the first material and of the metal oxide, possibly because of the nature of the interface between the first material and the metal oxide. |
| FILED | Wednesday, December 14, 2022 |
| APPL NO | 18/080905 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/628 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/19 (20210101) C25B 9/23 (20210101) C25B 13/04 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/40 (20130101) G01N 27/4073 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/122 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/004 (20130101) H01M 8/126 (20130101) H01M 8/0271 (20130101) H01M 8/1006 (20130101) H01M 8/1007 (20160201) H01M 8/1016 (20130101) H01M 8/1246 (20130101) H01M 8/1253 (20130101) H01M 2008/1293 (20130101) H01M 2300/0071 (20130101) H01M 2300/0074 (20130101) H01M 2300/0077 (20130101) H01M 2300/0091 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072281 | O'Rourke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Battelle Savannah River Alliance, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Patrick E. O'Rourke (Martinez, Georgia); Kimberly Alicia Strange Fessler (Aiken, South Carolina); Donald J. Pak (Martinez, Georgia) |
| ABSTRACT | Optical cells are described for use in spectroscopy applications. The cells include a series of discrete planar reflectors aligned with one another and spaced apart from one another at each end of the sample cavity. The discrete planar reflectors can be surrounded by transparent windows and divergent energy can be removed from the cell cavity via the windows. The cells can define a unique beam path for the energy beam, and there can be no overlapping optical paths through the cell. The cells can provide well-defined detection signals with very high signal-to-noise ratio. |
| FILED | Wednesday, October 23, 2019 |
| APPL NO | 16/661528 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) G01N 21/255 (20130101) Original (OR) Class G01N 2201/0612 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072290 | Angel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Stanley Michael Angel (Columbia, South Carolina); Jerry Chance Carter (Livermore, California) |
| ABSTRACT | A hyperspectral imaging apparatus based on a monolithic or free space optical spatial heterodyne spectrometer (SHS) design, array detector, electromagnetic radiation source, and optical collection element is described. The apparatus enables the simultaneous acquisition of spatially isolated Fizeau fringe patterns, each having an encoded light product that is decoded to produce a spectral fingerprint of the interrogated object. Features specific to the SHS, such as a large entrance aperture, large acceptance angle, and no moving parts, enable a variety of optical collection schemes including lens arrays, solid-core and hollow core waveguides, and others. In one example, a microlens array (MLA) is configured with the hyperspectral imaging apparatus to simultaneously image many hundred spatially isolated Fizeau fringe patterns while interrogating an object using an electromagnetic radiation source. Each Fizeau fringe pattern recorded by the array detector is decoded to produce a full Raman or laser-induced breakdown spectroscopy (LIBS) spectrum. Compared to prior art, the hyperspectral imaging apparatus overcomes the primary limitations of needing to trade time resolution for both spectral and spatial data density because the imaging apparatus simultaneously acquires both spectral and special information. Based on the selection and configuration of diffraction gratings, the grating aperture size, Littrow wavelength (i.e., heterodyne wavelength), and optical collection configuration, the apparatus can be tailored to produced low or high spectral resolution with a spectral bandpass that covers a portion or the entire Raman spectral range (up to 4200 cm−1) and for LIBS as well. |
| FILED | Friday, September 11, 2020 |
| APPL NO | 17/772265 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 2201/0633 (20130101) G01N 2201/0635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072453 | Brodsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jason Philip Brodsky (Livermore, California); Nathaniel Sean Bowden (Livermore, California) |
| ABSTRACT | The present disclosure relates to a method for detecting incoming radiation having a plurality of differing properties including at least one of differing types, differing energies or differing incoming directions. The method involves using a scintillator structure formed from first and second dissimilar scintillator materials, where the first and second dissimilar scintillator materials emit first and second different colors of light in response to the incoming radiation. A first light detector is used for detecting light having the first color, and a second light detector is used for detecting light having the second color. A first output signal is generated in response to the detection of light having the first color, and a second output signal is generated in response to detecting light having the second color. The first and second output signals are then analyzed to determine at least one property of the incoming radiation. |
| FILED | Tuesday, June 21, 2022 |
| APPL NO | 17/845322 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/201 (20130101) G01T 1/2002 (20130101) G01T 1/2006 (20130101) Original (OR) Class G01T 1/2033 (20130101) G01T 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073952 | Nygaard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BWXT Technical Services Group, Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | BWXT Technical Services Group, Inc. (Lynchburg, Virginia) |
| INVENTOR(S) | Erik T. Nygaard (Lynchburg, Virginia); Peter L. Angelo (Oak Ridge, Tennessee); Scott B. Aase (Aiken, South Carolina) |
| ABSTRACT | The present invention relates generally to the field of compensation methods for nuclear reactors and, in particular to a method for fail-safe reactivity compensation in solution-type nuclear reactors. In one embodiment, the fail-safe reactivity compensation method of the present invention augments other control methods for a nuclear reactor. In still another embodiment, the fail-safe reactivity compensation method of the present invention permits one to control a nuclear reaction in a nuclear reactor through a method that does not rely on moving components into or out of a reactor core, nor does the method of the present invention rely on the constant repositioning of control rods within a nuclear reactor in order to maintain a critical state. |
| FILED | Wednesday, June 16, 2021 |
| APPL NO | 17/349595 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 1/24 (20130101) G21C 3/24 (20130101) G21C 7/30 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12074213 | Nuzzo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Ralph G. Nuzzo (Champaign, Illinois); John A. Rogers (Wilmette, Illinois); Etienne Menard (Voglans, France); Keon Jae Lee (Daejeon, South Korea); Dahl-Young Khang (Seoul, South Korea); Yugang Sun (Gladwyne, Pennsylvania); Matthew Meitl (Durham, North Carolina); Zhengtao Zhu (Rapid City, South Dakota) |
| ABSTRACT | The invention provides methods and devices for fabricating printable semiconductor elements and assembling printable semiconductor elements onto substrate surfaces. Methods, devices and device components of the present invention are capable of generating a wide range of flexible electronic and optoelectronic devices and arrays of devices on substrates comprising polymeric materials. The present invention also provides stretchable semiconductor structures and stretchable electronic devices capable of good performance in stretched configurations. |
| FILED | Thursday, June 24, 2021 |
| APPL NO | 17/357697 |
| ART UNIT | 2829 — Semiconductors/Memory |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/0185 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/308 (20130101) H01L 21/322 (20130101) H01L 21/02521 (20130101) H01L 21/02603 (20130101) H01L 21/02628 (20130101) H01L 21/6835 (20130101) H01L 23/02 (20130101) H01L 24/03 (20130101) H01L 24/05 (20130101) H01L 24/08 (20130101) H01L 24/29 (20130101) H01L 24/32 (20130101) H01L 24/80 (20130101) H01L 24/83 (20130101) H01L 24/94 (20130101) H01L 24/97 (20130101) H01L 25/0753 (20130101) H01L 27/1285 (20130101) H01L 27/1292 (20130101) H01L 29/04 (20130101) H01L 29/06 (20130101) H01L 29/12 (20130101) H01L 29/068 (20130101) H01L 29/76 (20130101) Original (OR) Class H01L 29/0665 (20130101) H01L 29/0673 (20130101) H01L 29/0676 (20130101) H01L 29/78603 (20130101) H01L 29/78681 (20130101) H01L 29/78696 (20130101) H01L 31/0392 (20130101) H01L 31/1804 (20130101) H01L 31/1864 (20130101) H01L 31/1896 (20130101) H01L 31/03926 (20130101) H01L 33/007 (20130101) H01L 33/32 (20130101) H01L 33/0093 (20200501) H01L 2221/68368 (20130101) H01L 2221/68381 (20130101) H01L 2224/03 (20130101) H01L 2224/03 (20130101) H01L 2224/03 (20130101) H01L 2224/80 (20130101) H01L 2224/80 (20130101) H01L 2224/83 (20130101) H01L 2224/83 (20130101) H01L 2224/94 (20130101) H01L 2224/94 (20130101) H01L 2224/95 (20130101) H01L 2224/97 (20130101) H01L 2224/97 (20130101) H01L 2224/97 (20130101) H01L 2224/0332 (20130101) H01L 2224/0332 (20130101) H01L 2224/0345 (20130101) H01L 2224/0362 (20130101) H01L 2224/2919 (20130101) H01L 2224/2919 (20130101) H01L 2224/03614 (20130101) H01L 2224/05073 (20130101) H01L 2224/05073 (20130101) H01L 2224/05082 (20130101) H01L 2224/05082 (20130101) H01L 2224/05124 (20130101) H01L 2224/05124 (20130101) H01L 2224/05144 (20130101) H01L 2224/05144 (20130101) H01L 2224/05144 (20130101) H01L 2224/05155 (20130101) H01L 2224/05155 (20130101) H01L 2224/05155 (20130101) H01L 2224/05166 (20130101) H01L 2224/05166 (20130101) H01L 2224/05166 (20130101) H01L 2224/05552 (20130101) H01L 2224/05552 (20130101) H01L 2224/05553 (20130101) H01L 2224/05553 (20130101) H01L 2224/05554 (20130101) H01L 2224/05554 (20130101) H01L 2224/05555 (20130101) H01L 2224/05555 (20130101) H01L 2224/05644 (20130101) H01L 2224/05644 (20130101) H01L 2224/05644 (20130101) H01L 2224/05644 (20130101) H01L 2224/05666 (20130101) H01L 2224/05666 (20130101) H01L 2224/08225 (20130101) H01L 2224/8385 (20130101) H01L 2224/9202 (20130101) H01L 2224/9202 (20130101) H01L 2224/32225 (20130101) H01L 2224/32225 (20130101) H01L 2224/80006 (20130101) H01L 2224/80121 (20130101) H01L 2224/80121 (20130101) H01L 2224/80862 (20130101) H01L 2224/80895 (20130101) H01L 2224/83005 (20130101) H01L 2224/83121 (20130101) H01L 2224/83121 (20130101) H01L 2224/83192 (20130101) H01L 2224/83192 (20130101) H01L 2224/83193 (20130101) H01L 2224/83862 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/00012 (20130101) H01L 2924/00012 (20130101) H01L 2924/00012 (20130101) H01L 2924/00012 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/00014 (20130101) H01L 2924/14 (20130101) H01L 2924/14 (20130101) H01L 2924/0665 (20130101) H01L 2924/0665 (20130101) H01L 2924/01032 (20130101) H01L 2924/01032 (20130101) H01L 2924/01032 (20130101) H01L 2924/1305 (20130101) H01L 2924/1305 (20130101) H01L 2924/1306 (20130101) H01L 2924/1306 (20130101) H01L 2924/1461 (20130101) H01L 2924/1461 (20130101) H01L 2924/1579 (20130101) H01L 2924/10253 (20130101) H01L 2924/10329 (20130101) H01L 2924/12032 (20130101) H01L 2924/12032 (20130101) H01L 2924/12036 (20130101) H01L 2924/12036 (20130101) H01L 2924/12041 (20130101) H01L 2924/12042 (20130101) H01L 2924/12042 (20130101) H01L 2924/12043 (20130101) H01L 2924/12043 (20130101) H01L 2924/12044 (20130101) H01L 2924/12044 (20130101) H01L 2924/13055 (20130101) H01L 2924/13055 (20130101) H01L 2924/13063 (20130101) H01L 2924/13063 (20130101) H01L 2924/13091 (20130101) H01L 2924/13091 (20130101) H01L 2924/15159 (20130101) H01L 2924/15162 (20130101) H01L 2924/15788 (20130101) H01L 2924/15788 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/547 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 977/707 (20130101) Y10S 977/724 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12074321 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Apple Inc. (Cupertino, California) |
| ASSIGNEE(S) | Apple Inc. (Cupertino, California) |
| INVENTOR(S) | Hongli Dai (Los Altos, California); Huiming Wu (San Jose, California); Chi-Kai Lin (Sunnyvale, California); Michael J. Erickson (San Jose, California); Xiaoping Wang (Naperville, Illinois); Yan Li (Westmont, Illinois); Yanjie Cui (Arlington Heights, Illinois); James A. Gilbert (Bolingbrook, Illinois); Zhenzhen Yang (Westmont, Illinois); Anh D. Vu (Lemont, Illinois); Arthur Jeremy Kropf (Westmont, Illinois); Hakim H. Iddir (Hoffman Estates, Illinois); Christopher S. Johnson (Naperville, Illinois); John David Carter (Bolingbrook, Illinois) |
| ABSTRACT | Compounds, particles, and cathode active materials that include lithium, cobalt, manganese, nickel, aluminum, and other elements can be used in lithium ion batteries. The cathode active materials include compounds having the general Formula (I): compound represented by Formula (I): LiαCO1-x-y-zMewMnxNiyAlzOδ, as well as Formula (II): LiαCO1-s-u-vMesMntNiuAlyOδ. |
| FILED | Friday, August 21, 2020 |
| APPL NO | 16/999328 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/50 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/84 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/366 (20130101) H01M 4/483 (20130101) H01M 4/505 (20130101) Original (OR) Class H01M 4/525 (20130101) H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12075201 | Michelogiannakis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Georgios Michelogiannakis (Berkeley, California); Yiwen Shen (New York, New York); Min Yee Teh (New York, New York); John Shalf (Oakland, California); Madeleine Glick (New York, New York); Keren Bergman (New York, New York) |
| ABSTRACT | Disclosed herein are methods, systems, and devices for bandwidth steering. Systems may include a plurality of compute nodes configured to execute one or more applications, a plurality of first level resources communicatively coupled to the plurality of compute nodes, a plurality of second level resources communicatively coupled to the plurality of first level resources, and a plurality of third level resources communicatively coupled to the plurality of second level resources. Systems may also include a plurality of optical switch circuits communicatively coupled to the plurality of first level resources and the plurality of second level resources, wherein each of the plurality of optical switch circuits is coupled to more than one of the plurality of the first level resources and is also coupled to more than one of the plurality of the second level resources. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/775820 |
| ART UNIT | 2635 — Optical Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/12 (20130101) Selecting H04Q 11/0005 (20130101) H04Q 11/0062 (20130101) Original (OR) Class H04Q 2011/0052 (20130101) H04Q 2011/0073 (20130101) H04Q 2011/0086 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12075555 | Kobernik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SHINE Technologies, LLC (Janesville, Wisconsin) |
| ASSIGNEE(S) | SHINE Technologies, LLC (Janesville, Wisconsin) |
| INVENTOR(S) | Arne Kobernik (Monona, Wisconsin); Carl Sherven (Monona, Wisconsin); Casey Lamers (Monona, Wisconsin); Chris Seyfert (Monona, Wisconsin); Evan Sengbusch (Monona, Wisconsin); Gabriel Becerra (Monona, Wisconsin); Jin Lee (Monona, Wisconsin); Logan Campbell (Monona, Wisconsin); Mark Thomas (Monona, Wisconsin); Michael Taylor (Monona, Wisconsin); Preston Barrows (Monona, Wisconsin); Ross Radel (Monona, Wisconsin); Tye Gribb (Monona, Wisconsin) |
| ABSTRACT | Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes. |
| FILED | Thursday, June 01, 2023 |
| APPL NO | 18/204659 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/08 (20130101) H01J 37/32082 (20130101) H01J 41/04 (20130101) H01J 41/14 (20130101) Spark Gaps; Overvoltage Arresters Using Spark Gaps; Sparking Plugs; Corona Devices; Generating Ions to be Introduced into Non-enclosed Gases H01T 23/00 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 31/26 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) H05H 1/54 (20130101) H05H 1/4622 (20210501) H05H 3/06 (20130101) H05H 5/04 (20130101) H05H 6/00 (20130101) H05H 7/22 (20130101) Original (OR) Class H05H 9/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12075639 | Hammond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); SolarWindow Technologies, Inc. (Scottsdale, Arizona) |
| ASSIGNEE(S) | Solarwindow Technologies, Inc. (Scottsdale, Arizona); Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Scott R. Hammond (Wheat Ridge, Colorado); Marinus Franciscus Antonius Maria van Hest (Golden, Colorado); John A. Conklin (Apalachin, New York) |
| ABSTRACT | Visually undistorted thin film electronic devices are provided. In one embodiment, a method for producing a thin-film electronic device comprises: opening a scribe in a stack of thin film material layers deposited on a substrate to define an active region and an inactive region of the thin-film electronic device, the stack comprising at least one active semiconductor layer. The active region comprises a non-scribed area of the stack and the inactive region comprises a region of the stack where thin film material was removed by the scribe. The method further comprises depositing at least one scribe fill material into a gap opened by the scribe. The scribe fill material has embedded therein one or more coloring elements that alter an optical characteristics spectrum of the inactive region to obtain an optical characteristics spectrum of the active region within a minimum perceptible difference for an industry defined standard observer. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/164834 |
| ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0465 (20141201) Organic electric solid-state devices H10K 30/80 (20230201) Original (OR) Class H10K 39/10 (20230201) H10K 71/00 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12075697 | Bazan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Guillermo C. Bazan (Goleta, California); Thomas S. Van Der Poll (Goleta, California); Thuc-Quyen Nguyen (Santa Barbara, California); John Love (Goleta, California) |
| ABSTRACT | Small organic molecule chromophores containing a benzo[c][1,2,5]thiadiazole with an electron-withdrawing substituent W in the 5-position (5BTH), benzo[c][1,2,5]oxadiazole with an electron-withdrawing substituent W in the 5-position (5BO), 2H-benzo[d][1,2,3]triazole (5BTR) with an electron-withdrawing substituent W in the 5-position (5BTR), 5-fluorobenzo[c][1,2,5]thiadiazole (FBTH), 5-fluorobenzo[c][1,2,5]oxadiazole (FBO), or 5-fluoro-2H-benzo[d][1,2,3]triazole (FBTR) core structure are disclosed. Such compounds can be used in organic heterojunction devices, such as organic small molecule solar cells and transistors. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 17/412135 |
| ART UNIT | 1699 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Heterocyclic Compounds C07D 495/04 (20130101) C07D 519/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/0816 (20130101) Organic electric solid-state devices H10K 30/00 (20230201) H10K 30/30 (20230201) H10K 85/40 (20230201) H10K 85/215 (20230201) H10K 85/655 (20230201) H10K 85/657 (20230201) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12075701 | Sonde et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Epir, Inc. (Bolingbrook, Illinois) |
| ASSIGNEE(S) | EPIR, INC. (Bolingbrook, Illinois) |
| INVENTOR(S) | Sushant Sonde (Westmont, Illinois); Yong Chang (Naperville, Illinois); Silviu Velicu (Willowbrook, Illinois); Srinivasan Krishnamurthy (Cupertino, California) |
| ABSTRACT | A Terahertz Source and Detector device is provided that includes a nanostructured metasurface configured to transmit fully into a layer of absorbing material below the metasurface to achieve transparent conductivity in the visible spectrum region, wherein the metasurface is composed of crystalline material with very high mobility. The crystalline material can be composed of HgCdTe. The HgCdTe material can have a bandgap of about 700 meV. The intrinsic carrier concentration can be 1012 cm−3 at 300K. |
| FILED | Monday, November 01, 2021 |
| APPL NO | 17/516228 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Electric solid-state devices not otherwise provided for H10N 15/15 (20230201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 12070399 | Hansen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Andrew Hansen (Minneapolis, Minnesota); Gregory Owen Voss (Minneapolis, Minnesota); Eric Nickel (Minneapolis, Minnesota); Emily Hein (Minneapolis, Minnesota) |
| ABSTRACT | Disclosed herein are devices, systems, and methods for accommodating quick and easy exchange of footwear for lower limb amputees. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Monday, June 17, 2019 |
| APPL NO | 17/253294 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/6607 (20130101) Original (OR) Class A61F 2002/6642 (20130101) A61F 2002/6671 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071668 | Tsalik et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina); United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Ephraim L. Tsalik (Cary, North Carolina); Geoffrey S. Ginsburg (Durham, North Carolina); Christopher W. Woods (Durham, North Carolina); Ricardo Henao Giraldo (Durham, North Carolina); Rachel A. Myers (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure provides methods for determining whether a subject has sepsis, or is at risk of developing sepsis, and methods of treating the subject based on the determination. Also provided are methods for determining an increased risk of mortality in a subject with sepsis or suspected of having sepsis, and methods of treating the subject based on the determination. Systems useful for the same are also provided. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/651579 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072889 | Woods |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Anne S Woods (San Francisco, California) |
| ABSTRACT | An intermediate data object is described that bridges source data to analysis-ready variables (ARVs). |
| FILED | Monday, November 04, 2019 |
| APPL NO | 17/290933 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2474 (20190101) G06F 16/2477 (20190101) G06F 16/24561 (20190101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073560 | Madabhushi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia); University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Sepideh Azarianpour Esfahani (Cleveland Heights, Ohio); Haider Mahdi (Wexford, Pennsylvania) |
| ABSTRACT | Various embodiments of the present disclosure are directed towards a method for generating a risk group classification for an African American (AA) patient. The method includes extracting a first plurality of architectural features from a digitized H&E slide image of the AA patient. A risk score for the AA patient is generated based on the first plurality of architectural features, where the risk score is prognostic of overall survival (OS) of the AA patient. The risk group classification is generated for the AA patient, where generating the risk group classification includes classifying the AA patient into either a high risk group or a low risk group based on the risk score, where the high risk group indicates the AA patient will die before a threshold date and the low risk group indicates the AA patient will die after or on the threshold date. |
| FILED | Tuesday, February 15, 2022 |
| APPL NO | 17/671882 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/30024 (20130101) G06T 2207/30096 (20130101) Image or Video Recognition or Understanding G06V 10/764 (20220101) G06V 10/774 (20220101) G06V 20/698 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12070282 | Farritor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Shane Farritor (Lincoln, Nebraska); Tom Frederick (Gretna, Nebraska); Kearney Lackas (Lincoln, Nebraska); Joe Bartels (Pittsburgh, Pennsylvania); Jacob Greenburg (Lincoln, Nebraska) |
| ABSTRACT | The various embodiments herein relate to robotic surgical systems and devices that use force and/or torque sensors to measure forces applied at various components of the system or device. Certain implementations include robotic surgical devices having one or more force/torque sensors that detect or measure one or more forces applied at or on one or more arms. Other embodiments relate to systems having a robotic surgical device that has one or more sensors and an external controller that has one or more motors such that the sensors transmit information that is used at the controller to actuate the motors to provide haptic feedback to a user. |
| FILED | Tuesday, July 07, 2020 |
| APPL NO | 16/922560 |
| ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Original (OR) Class A61B 34/76 (20160201) A61B 2090/064 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/1602 (20130101) B25J 9/1633 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 2219/36432 (20130101) G05B 2219/39181 (20130101) G05B 2219/39194 (20130101) G05B 2219/39321 (20130101) G05B 2219/40619 (20130101) G05B 2219/45117 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/27 (20130101) Y10S 901/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072286 | Bathel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Brett F. Bathel (Yorktown, Virginia); Joshua M. Weisberger (Newport News, Virginia) |
| ABSTRACT | A digital projection and reflected glare reduction system according to various aspects of the present technology may include a digital display device capable of generating a one or two dimensional source grid pattern back-illuminated by a light source to project an image of a source grid onto a retroreflective background. The projected source grid image may then be re-imaged onto the original grid element at a slight offset eliminating the need to generate a separate cutoff grid thereby reducing the amount of time required to setup and adjust the system. The digital display device is also capable of switching between a schlieren visualization capability to some other visualization capability (such as particle tracking velocimetry (PTV), particle imaging velocimetry (NV), temperature sensitive paint measurements (TSP), pressure sensitive paint measurements (PSP), photogrammetry, etc.) allowing for the simultaneous use of two different imaging techniques. |
| FILED | Thursday, September 30, 2021 |
| APPL NO | 17/490612 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/455 (20130101) Original (OR) Class G01N 21/958 (20130101) Optical Elements, Systems, or Apparatus G02B 27/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072290 | Angel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina); LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Stanley Michael Angel (Columbia, South Carolina); Jerry Chance Carter (Livermore, California) |
| ABSTRACT | A hyperspectral imaging apparatus based on a monolithic or free space optical spatial heterodyne spectrometer (SHS) design, array detector, electromagnetic radiation source, and optical collection element is described. The apparatus enables the simultaneous acquisition of spatially isolated Fizeau fringe patterns, each having an encoded light product that is decoded to produce a spectral fingerprint of the interrogated object. Features specific to the SHS, such as a large entrance aperture, large acceptance angle, and no moving parts, enable a variety of optical collection schemes including lens arrays, solid-core and hollow core waveguides, and others. In one example, a microlens array (MLA) is configured with the hyperspectral imaging apparatus to simultaneously image many hundred spatially isolated Fizeau fringe patterns while interrogating an object using an electromagnetic radiation source. Each Fizeau fringe pattern recorded by the array detector is decoded to produce a full Raman or laser-induced breakdown spectroscopy (LIBS) spectrum. Compared to prior art, the hyperspectral imaging apparatus overcomes the primary limitations of needing to trade time resolution for both spectral and spatial data density because the imaging apparatus simultaneously acquires both spectral and special information. Based on the selection and configuration of diffraction gratings, the grating aperture size, Littrow wavelength (i.e., heterodyne wavelength), and optical collection configuration, the apparatus can be tailored to produced low or high spectral resolution with a spectral bandpass that covers a portion or the entire Raman spectral range (up to 4200 cm−1) and for LIBS as well. |
| FILED | Friday, September 11, 2020 |
| APPL NO | 17/772265 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 2201/0633 (20130101) G01N 2201/0635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12074685 | Bode et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Atlas Space Operations, Inc. (Traverse City, Michigan) |
| ASSIGNEE(S) | Atlas Space Operations, Inc. (Traverse City, Michigan) |
| INVENTOR(S) | Brad Arnold Bode (Pacific Palisades, California); Kyle Stephen Polich (Los Angeles, California) |
| ABSTRACT | Described herein are systems, methods, media, and devices for generating a satellite program for contacting satellites. In some embodiments, data including one or more targets for accessing a satellite constellation is obtained. Based on the data, a set of representations may be generated and candidate satellite constellation access programs may be determined based on the set of representations. For each program, a first score may be computed for each target to obtain a first set of scores, and a second score may be computed for each first score of the first set of scores to obtain a second set of scores. A satellite constellation access program may be selected from the candidate satellite access programs based on the second set of second scores. |
| FILED | Wednesday, August 09, 2023 |
| APPL NO | 18/447133 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 7/18513 (20130101) H04B 7/18519 (20130101) H04B 7/18526 (20130101) H04B 7/18539 (20130101) H04B 7/18547 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 12070031 | Maxwell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | Tyler Maxwell (Winter Haven, Florida); Swadeshmukul Santra (Winter Park, Florida); Parthiban Rajasekaran (Orlando, Florida) |
| ABSTRACT | Compositions and methods for systemic delivery of at least one cargo in a vascular plant. Compositions may include at least one cargo delivery particle, having a core and a shell; and at least one cargo disposed on the shell. The core may include at least one micronutrient. The shell may include a coating material. The at least one cargo delivery particle may have a size of less than about 10 nanometers. Methods may include administering an effective amount of the compositions to a plant. |
| FILED | Thursday, September 17, 2020 |
| APPL NO | 17/024195 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/26 (20130101) Original (OR) Class A01N 43/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071636 | Briggs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Robert E Briggs (Boone, Iowa); Fred M Tatum (Nevada, Iowa) |
| ABSTRACT | The present invention provides novel attenuated Pasteurella multocida strains that may be used, in live or killed form, to formulate vaccines that are highly protective against P. multocida infection in bovines, other mammals, and in birds. The present invention also identifies the combination of nanP and hyaC gene mutations as key to the provision of such vaccines. When appropriately formulated, antigenic material of numerous other bovine pathogens may be combined with the live attenuated Pasteurella multocida strains, to make effective combination vaccines. |
| FILED | Friday, September 17, 2021 |
| APPL NO | 17/478023 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/102 (20130101) A61K 2039/522 (20130101) A61K 2039/552 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) Original (OR) Class C12N 9/16 (20130101) Enzymes C12Y 101/01022 (20130101) C12Y 301/03029 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073554 | Wiedenhoeft et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alex Wiedenhoeft (Madison, Wisconsin); Prabu Ravindran (Madison, Wisconsin) |
| ABSTRACT | A method for identifying charcoal products includes capturing, by a camera, an image of a sample of charcoal. The method also includes analyzing, by a processor in communication with the camera, the image of the sample to identify characteristics of the sample. The method also includes comparing, by the processor, the identified characteristics to a plurality of signatures to determine a match between the identified characteristics and known characteristics associated with each signature in the plurality of signatures. The method further includes generating, by the processor, an output based on the comparison. |
| FILED | Thursday, July 08, 2021 |
| APPL NO | 17/370345 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/001 (20130101) Original (OR) Class G06T 7/11 (20170101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 12071214 | Long et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Liam Long (Washington, District of Columbia); Christian Burzycki (Washington, District of Columbia); Glen Armstrong (Washington, District of Columbia); Joseph Camean (Old Lyme, Connecticut) |
| ABSTRACT | A fluid transportation apparatus includes a first suction pipe having a first intake opening and a second suction pipe having a second intake opening. The first and second suction pipes are attached to a vessel on opposite sides to move in rolling motion. The first intake opening is disposed in a fluid reservoir at a position lower than the second intake opening and a valve device moves toward a maximally opened position for a first proximal end of the first suction pipe and to move toward a maximally closed position for a second proximal end of the second suction pipe, as the first and second suction pipes move with the vessel in a first rolling direction of the rolling motion. The intake openings reverse roles and the proximal ends reverse roles, as the vessel moves in a second rolling direction of the rolling motion opposite from the first rolling direction. |
| FILED | Wednesday, June 14, 2023 |
| APPL NO | 18/209672 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Marine Propulsion or Steering B63H 21/386 (20130101) Original (OR) Class Lubricating of Machines or Engines in General; Lubricating Internal Combustion Engines; Crankcase Ventilating F01M 2011/0075 (20130101) Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 17/363 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0923 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073341 | Ebert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | David Scott Ebert (West Lafayette, Indiana); Abish Malik (West Lafayette, Indiana); Sherry Towers (Tempe, Arizona); Ross Maciejewski (Phoenix, Arizona) |
| ABSTRACT | Disclosed herein is a visual analytics system and method that provides a proactive and predictive environment in order to assist decision makers in making effective resource allocation and deployment decisions. The challenges involved with such predictive analytics processes include end-users' understanding, and the application of the underlying statistical algorithms at the right spatiotemporal granularity levels so that good prediction estimates can be established. In the disclosed approach, a suite of natural scale templates and methods are provided allowing users to focus and drill down to appropriate geospatial and temporal resolution levels. The disclosed forecasting technique is based on the Seasonal Trend decomposition based on Loess (STL) method applied in a spatiotemporal visual analytics context to provide analysts with predicted levels of future activity. A novel kernel density estimation technique is also disclosed, in which the prediction process is influenced by the spatial correlation of recent incidents at nearby locations. |
| FILED | Monday, February 17, 2020 |
| APPL NO | 16/792785 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073482 | Vemury |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Arun Vemury (North Bethesda, Maryland) |
| ABSTRACT | Collection, validation, accuracy checking, and matching of information for individuals, e.g., in-scope people entering/exiting a country is described. The systems, techniques, devices, methods, and approaches described herein can be used to collect biographic, biometric, and travel information for persons who enter a country with the expectation that the person will eventually exit. The system and method described herein include structures and procedures for determining whether the individual, based on his/her information, meets a predefined criterion that is associated with predefined procedures, e.g., special precautions are to be implemented. This document also describes how information for an individual can be matched with an existing record in order to ensure accurate recordkeeping. |
| FILED | Wednesday, March 27, 2019 |
| APPL NO | 16/366584 |
| ART UNIT | 3685 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Electric Digital Data Processing G06F 16/22 (20190101) G06F 16/9535 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/40 (20240101) G06Q 50/265 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 12070443 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Rong Li (San Antonio, Texas); Bin Yuan (San Antonio, Texas); Tyler Curiel (San Antonio, Texas) |
| ABSTRACT | The present invention provides methods and compositions for treating or preventing breast cancer with S-equol. The method and compositions are particularly suited to treating triple-negative breast cancer. The S-equol may be administered alone or in combination with one or more cytotoxic or immunotherapeutic compound or molecule. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/372352 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) Original (OR) Class A61K 39/3955 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070444 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Rong Li (Washington, District of Columbia); Bin Yuan (Hefei, China PRC); Kate Ida Lathrop (San Antonio, Texas) |
| ABSTRACT | The present invention provides methods and compositions for modulating molecular markers, and hence treating or preventing breast cancer (e.g., triple-negative breast cancer) and melanoma with a pharmaceutically effective amount of S-equol or a pharmaceutical composition comprising S-equol. The S-equol may be administered alone or in combination with one or more cytotoxic or immunotherapeutic compound or molecule. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 17/535125 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) Original (OR) Class A61K 39/39541 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071610 | Fan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Zhonghui Hugh Fan (Gainesville, Florida); Xiao Jiang (Gainesville, Florida); Trevor B. Tilly (Gainesville, Florida); John Lednicky (Gainesville, Florida); Chang-Yu Wu (Gainesville, Florida) |
| ABSTRACT | An apparatus and method are provided for performing detection of microorganisms (e.g., viruses) with high sensitivity. The apparatus and method are well suited for point-of-care (POC) testing in resource-limited regions and are capable of being operated with very little manual intervention and without the need for lab equipment. A variety of viruses can be detected with high sensitivity, including, for example, coronaviruses, Zika virus and flu viruses. |
| FILED | Monday, January 04, 2021 |
| APPL NO | 17/140696 |
| ART UNIT | 1758 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/527 (20130101) B01L 2200/025 (20130101) B01L 2200/026 (20130101) B01L 2200/028 (20130101) B01L 2400/0616 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/44 (20130101) C12M 41/46 (20130101) Original (OR) Class C12M 41/48 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56916 (20130101) G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 12073492 | Shi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Luyao Shi (New Haven, Connecticut); Chi Liu (Orange, Connecticut); John Onofrey (Woodbridge, Connecticut); Hui Liu (Beijing, China PRC) |
| ABSTRACT | A system for estimating attenuation coefficients from only single photon emission computed tomography (SPECT) emission data using deep neural networks includes an artificial neural network based upon machine learning system estimating attenuation maps for SPECT emission data, and associated attenuation correction method. |
| FILED | Friday, April 17, 2020 |
| APPL NO | 17/594364 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 11/003 (20130101) Original (OR) Class G06T 2207/10108 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073559 | Asiedu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Mercy Asiedu (Durham, North Carolina); Nirmala Ramanujam (Durham, North Carolina); Guillermo Sapiro (Durham, North Carolina) |
| ABSTRACT | A method for automated detection of cervical pre-cancer includes: providing at least one cervigram; pre-processing the at least one cervigram; extracting features from the at least one pre-processed cervigram; and classifying the at least one cervigram as negative or positive for cervical pre-cancer based on the extracted features. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/282093 |
| ART UNIT | 2635 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/000094 (20220201) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/136 (20170101) G06T 7/168 (20170101) G06T 2207/20024 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20132 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 12071456 | Schellenberger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AMUNIX PHARMACEUTICALS, INC. (South San Francisco, California) |
| ASSIGNEE(S) | AMUNIX PHARMACEUTICALS, INC. (South San Francisco, California) |
| INVENTOR(S) | Volker Schellenberger (Palo Alto, California); Joshua Silverman (Los Altos Hills, California); Chia-wei Wang (Santa Clara, California); Benjamin Spink (San Carlos, California); Willem P. Stemmer (Los Gatos, California); Nathan Geething (Natick, Massachusetts); Wayne To (Fremont, California); Jeffrey L. Cleland (San Carlos, California) |
| ABSTRACT | The present invention relates to compositions comprising biologically active proteins linked to extended recombinant polypeptide (XTEN), isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of glucose-related diseases, metabolic diseases, coagulation disorders, and growth hormone-related disorders and conditions. |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150426 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/001 (20130101) C07K 14/47 (20130101) Original (OR) Class C07K 14/61 (20130101) C07K 14/545 (20130101) C07K 14/605 (20130101) C07K 14/745 (20130101) C07K 2319/31 (20130101) C07K 2319/35 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/644 (20130101) C12N 9/6437 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12073561 | Buckler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| INVENTOR(S) | Andrew J. Buckler (Boston, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts); Mark A. Buckler (Wenham, Massachusetts); Vladimir Valtchinov (Waban, Massachusetts); David S. Paik (Moon Bay, California) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Wednesday, February 08, 2023 |
| APPL NO | 18/166284 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/24 (20230101) G06F 18/211 (20230101) G06F 18/2148 (20230101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 3/00 (20130101) G06T 5/73 (20240101) G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10048 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10101 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/30096 (20130101) G06T 2207/30104 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/764 (20220101) G06V 20/69 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 12072277 | Cooksey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Gregory Alan Cooksey (Gaithersburg, Maryland); Paul Nathan Patrone (Washington Grove, Maryland); Anthony Jose Kearsley (Hanover, Maryland) |
| ABSTRACT | A multiplexed amplitude modulation photometer includes a microchannel; a first input light path that: receives a first modulated light at a first modulation frequency; and communicates the first modulated light to a first optical region that receives the first analyte that produces a first output light including the first modulation frequency communicated to a first detection light path; the first optical region; the first detection light path that receives the first output light; a second input light path that: receives a second modulated light with a second modulation frequency; and communicates second modulated light to a second optical region that receives the second analyte that produces a second output light with the second modulation frequency communicated to a second detection light path; the second optical region; and the second detection light path that receives the second output light from the second optical region. |
| FILED | Friday, October 30, 2020 |
| APPL NO | 17/084683 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1404 (20130101) G01N 15/1436 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 12073559 | Asiedu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Mercy Asiedu (Durham, North Carolina); Nirmala Ramanujam (Durham, North Carolina); Guillermo Sapiro (Durham, North Carolina) |
| ABSTRACT | A method for automated detection of cervical pre-cancer includes: providing at least one cervigram; pre-processing the at least one cervigram; extracting features from the at least one pre-processed cervigram; and classifying the at least one cervigram as negative or positive for cervical pre-cancer based on the extracted features. |
| FILED | Friday, October 04, 2019 |
| APPL NO | 17/282093 |
| ART UNIT | 2635 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/000094 (20220201) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 7/136 (20170101) G06T 7/168 (20170101) G06T 2207/20024 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/20132 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 12070737 | Eltoni et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KING SAUD UNIVERSITY (Riyadh, Saudi Arabia) |
| ASSIGNEE(S) | KING SAUD UNIVERSITY (Riyadh, Saudi Arabia) |
| INVENTOR(S) | Ahmed Eltoni Mohamed Ali Eltoni (Riyadh, Saudi Arabia); Mohamed Abdelaty Habila (Riyadh, Saudi Arabia); Joselito Puzon Labis (Riyadh, Saudi Arabia); Ali Kanakhr Aldalbahi (Riyadh, Saudi Arabia); Asharf Elsayed Khater (Cairo, Egypt); Huda Saad Alnafie (Buraidah, Saudi Arabia) |
| ABSTRACT | Amino-rich anionic mesoporous silica (AMS) nanoparticles prepared through adding two different types of co-structuring directing agent (CSDA) molecules, thus increasing the amino amount within the AMS together with preserving ordered porous structure. Further boosting of amino amount can be accomplished through linking three different CSDA molecules together. Amino-functionalized mesoporous silica can be obtained with high amino amounts with linking either double or triple CSDA molecules while preserving ordered mesoporous structure and high textural properties. |
| FILED | Tuesday, October 17, 2023 |
| APPL NO | 18/380763 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/103 (20130101) B01J 20/3057 (20130101) Original (OR) Class B01J 20/3071 (20130101) B01J 20/3078 (20130101) B01J 20/3204 (20130101) B01J 20/3244 (20130101) B01J 20/28061 (20130101) B01J 20/28071 (20130101) B01J 20/28073 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/281 (20130101) C02F 1/285 (20130101) C02F 1/288 (20130101) C02F 2101/006 (20130101) C02F 2101/20 (20130101) C02F 2101/308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12070869 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WON KWANG S and T CO., LTD. (Incheon, South Korea) |
| ASSIGNEE(S) | WON KWANG S and T CO., LTD. (Incheon, South Korea) |
| INVENTOR(S) | Sang Hun Lee (Incheon, South Korea); Jun Kee Kim (Seoul, South Korea); Tae Eun Lee (Incheon, South Korea); Cheong Min Noh (Incheon, South Korea) |
| ABSTRACT | A solar panel cutting unit includes a frame, a panel transporting mechanism at the frame to lower the solar panel in a vertical direction, first guide roller units below the panel transporting mechanism to guide and lower the solar panel, a first wire cutting mechanism including first support rollers and a first cutting wire connecting the first support rollers to each other and extending in the same direction as the adhesion lines such that the first wire cutting mechanism separates one of the thin layers from the solar panel, and a second wire cutting mechanism below the first wire cutting mechanism and including second support rollers and a second cutting wire connecting the second support rollers to each other and moving in parallel to the first cutting wire such that the second wire cutting mechanism separates another of the thin layers from the solar panel. |
| FILED | Tuesday, October 26, 2021 |
| APPL NO | 17/783437 |
| ART UNIT | 3724 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Cutting; Details Common to Machines for Perforating, Punching, Cutting-out, Stamping-out or Severing B26D 1/0006 (20130101) B26D 1/553 (20130101) Original (OR) Class B26D 3/28 (20130101) B26D 2001/008 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071905 | Grove et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Donald E Grove (Cobalt, Connecticut); James K Berry (Bolton, Connecticut) |
| ABSTRACT | An engine control device may comprise a processor and a memory. The engine control device may be configured to modify a fuel flow based on a density of the fuel proximate a fuel nozzle. The engine control device may include a densimeter embedded in, or disposed proximate, the engine control device. The engine control device may include a temperature sensor embedded in, or disposed proximate, the engine control device. The engine control device may be electrically coupled to a fuel valve and/or configured to modulate the fuel valve based on a density of the fuel at the fuel valve. |
| FILED | Friday, October 14, 2022 |
| APPL NO | 17/966612 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/24 (20130101) F02C 7/222 (20130101) F02C 7/232 (20130101) F02C 9/26 (20130101) Original (OR) Class F02C 9/263 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071942 | Rutar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Matej Rutar (Manchester, Connecticut) |
| ABSTRACT | In accordance with at least one aspect of this disclosure, a variable displacement pump system can include, a variable displacement pump disposed in a main line and configured to supply pressure to receive a low pressure fluid and to output a high pressure fluid. The main line can connect a hydraulic fluid source to a plurality of system actuators, where the variable displacement pump is disposed in the main line between the hydraulic fluid source and the plurality of system actuators to pressurize the hydraulic fluid. |
| FILED | Friday, October 22, 2021 |
| APPL NO | 17/508600 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/232 (20130101) F02C 9/30 (20130101) F02C 9/38 (20130101) F02C 9/263 (20130101) Jet-propulsion Plants F02K 1/17 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 1/295 (20130101) F04B 1/324 (20130101) F04B 49/002 (20130101) Original (OR) Class F04B 49/08 (20130101) F04B 49/24 (20130101) F04B 49/065 (20130101) F04B 49/246 (20130101) F04B 2205/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12071974 | Griffin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON COMPANY (Waltham, Massachusetts) |
| INVENTOR(S) | Eric J. Griffin (Rancho Palos Verdes, California); Aryan Blourchian (Mission Viejo, California) |
| ABSTRACT | An eccentric bushing assembly comprises an outer eccentric bushing configured to be disposed in an opening of a panel comprising a central axis. The outer eccentric bushing is operable to float axially, rotate circumferentially, and to move radially with respect to the central axis. The eccentric bushing assembly further comprises an inner eccentric bushing disposed radially inward from the outer eccentric bushing and interfacing with the outer eccentric bushing, the inner eccentric bushing is operable to rotate relative to the outer eccentric bushing. The eccentric bushing assembly further comprises a spherical bushing comprising a through hole operable to receive a connecting pin therein and to rotate in at least one degree of freedom. The rotation of the spherical bushing can facilitate alignment of an axis of the pin with the through hole. |
| FILED | Monday, May 17, 2021 |
| APPL NO | 17/322831 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Finishing Work on Buildings, e.g Stairs, Floors E04F 13/0833 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 5/025 (20130101) Original (OR) Class F16B 5/0216 (20130101) F16B 12/2009 (20130101) F16B 2200/406 (20180801) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 23/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12072440 | Acharya et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | Girish Acharya (Redwood City, California); Douglas Bercow (Menlo Park, California); John Brian Burns (Palo Alto, California); Bradley J. Clymer (Austin, Texas); Aaron J. Heller (Belmont, California); Jeffrey Lubin (Princeton, New Jersey); Bhaskar Ramamurthy (Los Altos, California); David Watters (Sunnyvale, California); Aravind Sundaresan (San Jose, California) |
| ABSTRACT | An identification system includes a radar sensor configured to generate a time-domain or frequency-domain signal representative of electromagnetic waves reflected from one or more objects within a three-dimensional space over a period of time and a computation engine executing on one or more processors. The computation engine is configured to process the time-domain or frequency-domain signal to generate range and velocity data indicating motion by a living subject within the three-dimensional space. The computation engine is further configured to identify, based at least on the range and velocity data indicating the motion by the living subject, the living subject and output an indication of an identity of the living subject. |
| FILED | Wednesday, March 28, 2018 |
| APPL NO | 16/497968 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/412 (20130101) G01S 7/415 (20130101) Original (OR) Class G01S 7/417 (20130101) G01S 13/584 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, August 27, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240827.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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