FedInvent™ Patents
Patent Details for Tuesday, September 03, 2024
This page was updated on Tuesday, September 03, 2024 at 10:36 PM GMT
Department of Health and Human Services (HHS)
| US 12075844 | Carlson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| INVENTOR(S) | James B. Carlson (Durham, North Carolina); Jonathan W. Thornburg (Durham, North Carolina) |
| ABSTRACT | Apparatus for testing an electronic smoking (e-smoking) device includes an electronic circuit for electronically activating an e-smoking device and causing the e-smoking device to generate a plurality of puffs by converting a wicking fluid therein into a plurality of puffs without a need for a human to physically contact the e-smoking device during puff generation, and a wireless controller for controlling the electronic circuit. The electronic circuit is configured for activating the e-smoking device to generate the plurality of puffs based on wireless signals received at the wireless controller. The apparatus is further configured for measuring a characteristic of the e-smoking device, which may include a rate of conversion of the wicking fluid to vapor as a function of time for the plurality of puffs. |
| FILED | Friday, February 11, 2022 |
| APPL NO | 17/669759 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Smokers\' Requisites; Match Boxes; Simulated Smoking Devices A24F 40/10 (20200101) A24F 40/42 (20200101) A24F 40/80 (20200101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/02 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12075980 | Amirana et al. |
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| FUNDED BY |
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| APPLICANT(S) | The George Washington University (Washington, District of Columbia); 460Medical, Inc. (Weston, Massachusetts) |
| ASSIGNEE(S) | The George Washington University (Washington, District of Columbia); 460Medical, Inc. (Weston, Massachusetts) |
| INVENTOR(S) | Omar Amirana (Cambridge, Massachusetts); Kenneth C. Armstrong (Cary, North Carolina); Matthew W. Kay (Kensington, Maryland); Marco A. Mercader (Arlington, Virginia); Terrance J. Ransbury (Chapel Hill, North Carolina); Narine Sarvazyan (Potomac, Maryland) |
| ABSTRACT | Systems and methods for visualizing ablated tissue are disclosed. In some embodiments, a system for imaging tissue comprising: a catheter having a distal end and a proximal end; an inflatable balloon disposed about the distal end of the catheter; and an optical housing extending from the distal end of the catheter into the balloon, the optical housing being configured to position inside the balloon a light source for illuminating a tissue outside the balloon and a camera for imaging the illuminated tissue. |
| FILED | Friday, January 20, 2023 |
| APPL NO | 18/099480 |
| ART UNIT | 3797 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/05 (20130101) A61B 1/00009 (20130101) A61B 1/043 (20130101) Original (OR) Class A61B 1/00045 (20130101) A61B 1/00082 (20130101) A61B 1/00186 (20130101) A61B 1/0638 (20130101) A61B 1/0676 (20130101) A61B 1/0684 (20130101) A61B 5/004 (20130101) A61B 5/0044 (20130101) A61B 5/0084 (20130101) A61B 5/1459 (20130101) A61B 5/6853 (20130101) A61B 5/14503 (20130101) A61B 5/14546 (20130101) A61B 18/00 (20130101) A61B 18/1492 (20130101) A61B 90/30 (20160201) A61B 90/35 (20160201) A61B 90/361 (20160201) A61B 2018/0022 (20130101) A61B 2018/0212 (20130101) A61B 2034/301 (20160201) A61B 2090/365 (20160201) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076137 | Mujeeb-U-Rahman et al. |
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| FUNDED BY |
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| APPLICANT(S) | INTEGRATED MEDICAL SENSORS, INC. (Irvine, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Muhammad Mujeeb-U-Rahman (Irvine, California); Meisam Honarvar Nazari (Irvine, California); Mehmet Sencan (Tustin, California) |
| ABSTRACT | There is provided a glucose sensor system comprising: a transmitter (2) for containing a battery (212), the transmitter being for placement on top of patient skin; a transcutaneous connector (3) comprising at least one conductive path; and an implantable monolithic integrated circuit (I) for placement beneath the patient skin, wherein the implantable monolithic integrated circuit comprises a potentiostat and an electrochemical sensing element; wherein the potentiostat is electrically coupled to the transmitter (2) via the transcutaneous connector (3), and the electrochemical sensing element is configured to sense glucose concentration and generate an electrical signal representative of the glucose concentration, and wherein the potentiostat is electrically connected to the electrochemical sensing element. |
| FILED | Thursday, May 25, 2023 |
| APPL NO | 18/202071 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0004 (20130101) A61B 5/6848 (20130101) A61B 5/6849 (20130101) A61B 5/14532 (20130101) Original (OR) Class A61B 5/14865 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076150 | Trayanova et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Natalia A. Trayanova (Baltimore, Maryland); Henry R. Halperin (Baltimore, Maryland); Hermenegild Arevalo (Baltimore, Maryland); Jason Constantino (Baltimore, Maryland) |
| ABSTRACT | A method of planning a patient-specific cardiac procedure according to an embodiment of the current invention includes receiving three-dimensional imaging data of a patient's heart, simulating at least one of electrophysiological or electromechanical activity of at least a portion of the patient's heart using the three-dimensional imaging data, and planning the patient-specific cardiac procedure based on the simulating. The cardiac procedure is for providing a preselected alteration of at least one of electrophysiological or electromechanical behavior of the patient's heart. |
| FILED | Monday, August 17, 2020 |
| APPL NO | 16/995513 |
| ART UNIT | 1671 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/283 (20210101) Original (OR) Class A61B 5/319 (20210101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/466 (20130101) A61B 6/503 (20130101) A61B 6/5223 (20130101) A61B 8/13 (20130101) A61B 8/0883 (20130101) A61B 34/10 (20160201) A61B 2505/05 (20130101) A61B 2576/023 (20130101) Image Data Processing or Generation, in General G06T 19/00 (20130101) G06T 2210/41 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076193 | Bhuyan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Anshuman Bhuyan (Milpitas, California); Jung Woo Choe (Sunnyvale, California); Amin Nikoozadeh (Palo Alto, California); Butrus T. Khuri-Yakub (Palo Alto, California) |
| ABSTRACT | Ultrasound imaging and therapy with the same array of capacitive micromachined ultrasonic transducers is provided. The electronics includes a per-pixel switch for each transducer element. The switches provide an imaging mode driven completely by on-chip electronics and a therapy mode where off-chip pulsers provide relatively high voltages to the transducer elements. |
| FILED | Monday, June 19, 2023 |
| APPL NO | 18/337270 |
| ART UNIT | 3797 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/54 (20130101) Original (OR) Class A61B 8/4483 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) A61N 7/02 (20130101) A61N 2007/0021 (20130101) A61N 2007/0052 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0215 (20130101) B06B 1/0292 (20130101) B06B 2201/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076236 | Dasi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Lakshmi Prasad Dasi (Dublin, Ohio); Atieh Yousefi Koupaei (Columbus, Ohio); Megan Kristine Heitkemper (Columbus, Ohio) |
| ABSTRACT | A transcatheter prosthetic heart valve includes a stent frame and at least one sheet of leaflet material formed in to a tube, which includes a lower portion disposed on an exterior of the stent frame and an upper edge portion disposed within the stent frame. The upper edge portion includes at least a portion configured to wrap around a first portion of the top edge of the stent frame and fold towards an exterior of the stent frame. The upper edge portion also includes at least another portion configured to weave through the stent frame and fold towards the interior of the stent frame. |
| FILED | Tuesday, December 07, 2021 |
| APPL NO | 17/544194 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2415 (20130101) A61F 2/2418 (20130101) Original (OR) Class A61F 2/2433 (20130101) A61F 2210/0004 (20130101) A61F 2240/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076301 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Daniel C. Lu (Los Angeles, California); V. Reggie Edgerton (Los Angeles, California); Roland R. Roy (Playa Vista, California); Yury P. Gerasimenko (Los Angeles, California) |
| ABSTRACT | In various embodiments, methods are provided for applying transcutaneous and/or epidural spinal cord stimulation with and without selective pharmaceuticals to restore voluntary control of hand function in tetraplegic subjects. |
| FILED | Thursday, August 19, 2021 |
| APPL NO | 17/407043 |
| ART UNIT | 3796 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) Original (OR) Class A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/527 (20130101) A61K 31/4168 (20130101) A61K 31/4178 (20130101) A61K 31/4985 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) A61N 1/36003 (20130101) A61N 1/36034 (20170801) A61N 1/36067 (20130101) A61N 1/36171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076302 | Girardi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Michael Girardi (Madison, Connecticut); Julia Lewis (Clinton, Connecticut) |
| ABSTRACT | Described herein are methods and compositions useful to reduce (partially/inhibit or completely—prevent) skin cancer development in an individual in need thereof. |
| FILED | Tuesday, September 17, 2019 |
| APPL NO | 17/276800 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 31/165 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076329 | Isacoff et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V. (Munich, Germany); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell Univerisity (Ithaca, New York); MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V. (Munich, Germany); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Ehud Y. Isacoff (Berkeley, California); Johannes Broichhagen (Munich, Germany); Joshua T. Levitz (Ithaca, New York) |
| ABSTRACT | The present disclosure provides a conjugate comprising an affinity agent, a branched linker, and two or more photoisomerizable regulators. The present disclosure provides compositions comprising the conjugate, as well as devices comprising the compositions. The present disclosure provides methods for enhancing visual function, the methods comprising administering the conjugate to an individual in need thereof. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/332865 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/0008 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/52 (20130101) A61K 31/655 (20130101) Original (OR) Class A61K 35/76 (20130101) A61K 38/16 (20130101) A61K 47/40 (20130101) A61K 47/60 (20170801) A61K 47/65 (20170801) A61K 47/6849 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076332 | Bitan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Fondazione Telethon (Rome, Italy) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); FONDAZIONE TELETHON ETS (Rome, Italy) |
| INVENTOR(S) | Gal Bitan (Encino, California); Alessandro Fraldi (Rome, Italy); Irene Sambri (Rome, Italy); Antonio Monaco (Rome, Italy) |
| ABSTRACT | In various embodiments methods are provided for the treatment or prophylaxis of liposomal storage diseases. In certain embodiments the methods involve administering to a subject in need thereof one or more molecular tweezers that inhibit protein aggregation. |
| FILED | Thursday, April 25, 2019 |
| APPL NO | 17/050406 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/10 (20130101) A61K 31/19 (20130101) A61K 31/663 (20130101) Original (OR) Class A61K 31/6615 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076341 | Shafikhani |
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| FUNDED BY |
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| APPLICANT(S) | Rush University Medical Center (Chicago, Illinois) |
| ASSIGNEE(S) | Rush University Medical Center (Chicago, Illinois) |
| INVENTOR(S) | Sasha Shafikhani (Elmwood Park, Illinois) |
| ABSTRACT | Methods of administering apoptotic compensatory proliferation signaling vesicles (AC PS Vs), and pharmaceutical formulations thereof, are described herein. AC PS Vs can be used to promote proliferation of cells in injured or diseased tissues, for example by adding a therapeutically effective amount of APCSVs to the injured or diseased tissue. |
| FILED | Tuesday, June 18, 2019 |
| APPL NO | 17/252782 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 35/13 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076366 | Soliman et al. |
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| APPLICANT(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| ASSIGNEE(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| INVENTOR(S) | Tarik Soliman (Cambridge, Massachusetts); Laura M. Hales (Cambridge, Massachusetts); Daniel B. Hall (Easton, Massachusetts); Christopher So (Henderson, Nevada); Howard P. Sard (Arlington, Massachusetts); Vishnumurthy Hegde (Chelmsford, Massachusetts) |
| ABSTRACT | The invention provides non-hormonal vitamin D conjugated to apelin proteins that result in increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. In some embodiments, the vitamin D targeting groups are coupled to the apelin proteins via the third carbon on the vitamin D backbone. |
| FILED | Friday, July 03, 2020 |
| APPL NO | 16/920652 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/10 (20130101) Original (OR) Class A61K 38/22 (20130101) A61K 47/60 (20170801) A61K 47/551 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076382 | Hodge et al. |
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| APPLICANT(S) | GLOBEIMMUNE, INC. (Louisville, Colorado); The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | GlobeImmune, Inc. (Louisville, Colorado); The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | James Hodge (Kensington, Maryland); Jeffrey Schlom (Potomac, Maryland); Alex Franzusoff (Los Altos, California) |
| ABSTRACT | Disclosed are immunotherapeutic compositions and the concurrent use of combinations of such compositions for the improved induction of therapeutic immune responses and/or for the prevention, amelioration and/or treatment of disease, including, but not limited to, cancer and infectious disease. |
| FILED | Tuesday, January 24, 2023 |
| APPL NO | 18/158800 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/00117 (20180801) A61K 39/001102 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) A61K 39/001151 (20180801) A61K 39/001152 (20180801) A61K 39/001156 (20180801) A61K 39/001157 (20180801) A61K 39/001162 (20180801) A61K 39/001164 (20180801) A61K 39/001168 (20180801) A61K 39/001182 (20180801) A61K 39/001184 (20180801) A61K 39/001186 (20180801) A61K 39/001188 (20180801) A61K 39/001191 (20180801) A61K 39/001192 (20180801) A61K 39/001194 (20180801) A61K 39/001195 (20180801) A61K 2039/523 (20130101) A61K 2039/55522 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076387 | Watanabe et al. |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| INVENTOR(S) | Shinji Watanabe (Tokyo, Japan); Tokiko Watanabe (Osaka, Japan); Yoshihiro Kawaoka (Middleton, Wisconsin) |
| ABSTRACT | The invention provides a vaccine comprising an effective amount of an isolated recombinant influenza virus comprising a mutant M gene segment that is mutated so that upon viral replication the mutant M gene expresses a functional M1 protein and a mutant M2 protein with a deletion of the cytoplasmic tail and either lacking a transmembrane domain or having a mutated transmembrane domain. |
| FILED | Tuesday, April 13, 2021 |
| APPL NO | 17/229001 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/543 (20130101) A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076397 | Baker, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); NanoBio Corporation (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); BLUEWILLOW BIOLOGICS, INC. (Ann Arbor, Michigan) |
| INVENTOR(S) | James R. Baker, Jr. (Ann Arbor, Michigan); Douglas M. Smith (Ann Arbor, Michigan); Susan Ciotti (Ann Arbor, Michigan) |
| ABSTRACT | The present invention provides compositions comprising emulsion adjuvant and one or more active agents or substances formulated for infusion or injection into a subject (e.g., using a syringe and needle), as well as methods of formulating and using the same (e.g., as an injectable medicinal composition (e.g., a vaccine)). The emulsion adjuvant of an immunogenic composition of the invention in its preferred form comprises a cationic lipid containing a polar head group and a hydrophobic component (e.g., a dual chain hydrophobic group (e.g., the cationic surfactant dioctadecyl dimethyl ammonium chloride (DODAC) and dioctadecyl dimethyl ammonium bromine (DODAB))). Compositions of the invention comprising emulsion adjuvant and one or more active agents or substances formulated for administration via injection to a subject find use in treatment and/or prevention of infectious disease, cancer and/or allergy. |
| FILED | Wednesday, May 10, 2017 |
| APPL NO | 16/300423 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0043 (20130101) A61K 9/107 (20130101) A61K 38/38 (20130101) A61K 39/12 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 39/145 (20130101) A61K 47/10 (20130101) A61K 47/26 (20130101) A61K 47/34 (20130101) A61K 47/186 (20130101) A61K 2039/54 (20130101) A61K 2039/55566 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076409 | Camacho et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Kathryn M. Camacho (Los Angeles, California); Stefano Menegatti (Raleigh, North Carolina); Sunny Kumar (Aliso Viejo, California); Douglas Vogus (Goleta, California); Samir Mitragotri (Lexington, Massachusetts) |
| ABSTRACT | Pharmaceutical compositions comprising two or more therapeutically active agents, such as two or more anticancer agents, conjugated to one or more biocompatible polymers, wherein the molar ratio of the agents and/or schedules of delivery provide a synergistic therapeutic effect, are described. Methods of making and using the pharmaceutical compositions are further described. In one embodiment, the pharmaceutical compositions contain topoisomerase I and topoisomerase II inhibitors conjugated to the same or different biocompatible polymers. The two or more anticancer agents are covalently coupled to the polymer(s), and thereby can be delivered to a tumor at a molar ratio which provides a synergistic effect. Optionally, the agents are coupled indirectly to the polymer(s) via a linker. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 17/546480 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 47/61 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076421 | Dharmakumar et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Rohan Dharmakumar (Moorpark, California); Debiao Li (San Marino, California); Sotirios A. Tsaftaris (Lucca, Italy) |
| ABSTRACT | There are provided methods for diagnosing coronary heart disease in a subject in need thereof comprising administering an admixture comprising CO2 to a subject to reach a predetermined PaCO2 in the subject to induce hyperemia, monitoring vascular reactivity in the subject and diagnosing the presence or absence of coronary heart disease in the subject, wherein decreased vascular reactivity in the subject compared to a control subject is indicative of coronary heart disease. There are also provided methods for increasing sensitivity and specificity of BOLD MRI. |
| FILED | Tuesday, August 31, 2021 |
| APPL NO | 17/463073 |
| ART UNIT | 3798 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7076 (20130101) A61K 33/00 (20130101) A61K 49/08 (20130101) Original (OR) Class A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076437 | Coulombe et al. |
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| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | BROWN UNIVERSITY (Providence, Rhode Island) |
| INVENTOR(S) | Kareen L. K. Coulombe (Pawtucket, Rhode Island); Stephanie Roser (Florham Park, New Jersey); Fabiola Munarin (Smithfield, Rhode Island); Alicia Minor (Providence, Rhode Island) |
| ABSTRACT | The invention provides a highly versatile system to promote vascularization in ischemic tissue. The system is composed of a fully defined, customizable hydrogel loaded with a potent cocktail of proangiogenic growth factors. The hydrogel's mechanical, degradation, and factor release behavior can be tailored to the specifications of any given target tissue or ischemic disease state. The growth factor cocktail can be optimized for maximal vessel density or size to meet the perfusion specifications required by the tissue. The embodiments of the disclosure concern methods and compositions of the system, with examples of preparation for both injectable and implantable delivery modes. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/862962 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) Original (OR) Class A61K 38/30 (20130101) A61K 38/1825 (20130101) A61K 38/1858 (20130101) A61K 38/1866 (20130101) A61K 47/36 (20130101) A61K 47/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076568 | Asp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Anders J. Asp (Rochester, Minnesota); Jose L. Lujan (Byron, Minnesota) |
| ABSTRACT | In an example method for increasing synaptic gain in a region of a brain of a subject, a first electromagnetic pulse is applied to a first neural element of a first neuron of the subject using a first electrode. The first neural element includes a first synapse coupled to a second neuron of the subject. Subsequent to applying the first electromagnetic pulse to the first neural element, a second electromagnetic pulse is applied to a second neural element of the second neuron using a second electrode. |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 17/394366 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0529 (20130101) A61N 1/36125 (20130101) A61N 1/36167 (20130101) A61N 1/36192 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076590 | Konofagou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Elisa E. Konofagou (New York, New York); Fabrice Marquet (New York, New York); Yao-Sheng Tung (New York, New York) |
| ABSTRACT | Systems and methods for cavitation-guided opening of a targeted region of tissue within a primate skull are provided. In one example, a method includes delivering one or more microbubbles to proximate the targeted region, applying an ultrasound beam, using a transducer, through the skull of the primate to the targeted region to open the tissue, transcranially acquiring acoustic emissions produced from an interaction between the one or more microbubbles and the tissue, and determining a cavitation spectrum from the acquired acoustic emissions. |
| FILED | Wednesday, March 09, 2022 |
| APPL NO | 17/690523 |
| ART UNIT | 3798 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/481 (20130101) A61B 8/0808 (20130101) A61B 17/2258 (20130101) A61B 90/10 (20160201) A61B 2017/00106 (20130101) A61B 2017/22008 (20130101) A61B 2017/22089 (20130101) A61B 2090/378 (20160201) A61B 2503/40 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076719 | Douglas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
| INVENTOR(S) | Temple Douglas (Blacksburg, Virginia); Philip Melvin Graybill (Blacksburg, Virginia); Rafael Davalos (Blacksburg, Virginia) |
| ABSTRACT | Described herein are aspects of a microfluidic separation and assay system that can include a microfluidic contactless dielectrophoretic (cDEP) device, a microfluidic concentrator, and a microfluidic assay chamber. In some aspects, microfluidic separation and assay system can be included on a single microfluidic chip. Also described herein are methods of using the microfluidic separation and assay system described herein. |
| FILED | Tuesday, March 12, 2019 |
| APPL NO | 16/980362 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) Original (OR) Class B01L 3/502761 (20130101) B01L 2300/069 (20130101) B01L 2300/0645 (20130101) B01L 2300/0829 (20130101) B01L 2300/0883 (20130101) B01L 2400/0424 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077450 | Chakravarty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Shatadru Chakravarty (Rolla, Missouri); Erik M. Shapiro (Okemos, Michigan) |
| ABSTRACT | A nanoparticle composition is provided. The nanoparticle composition includes a plurality of nanoparticles, each nanoparticle of the plurality having a core including tantalum oxide, and a covalent coating covalently bound to the core. The covalent coating includes a surface modifier selected from the group consisting of (3-aminopropyl)trimethoxy silane (APTMS), (3-aminopropyl)triethoxy silane (APTES), APTMS-methoxy-poly(ethylene-glycol)-succinimidyl glutarate (APTMS-m-PEG-glutarate), APTES-methoxy-poly(ethylene-glycol)-succinimidyl glutarate (APTES-m-PEG-glutarate), 2-[methoxy (polyethyleneoxy)-9-12-propyl] trimethoxysilane (PEG-Silane), hexadecyltriethoxy silane, and combinations thereof. Methods of synthesizing and using the nanoparticle composition are also provided. |
| FILED | Tuesday, July 06, 2021 |
| APPL NO | 17/367919 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6923 (20170801) A61K 47/6929 (20170801) A61K 49/0428 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 35/00 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) C01P 2004/84 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077507 | Shokat et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kevan M. Shokat (San Francisco, California); Daniel Gentile (Darien, Connecticut); Steven Moss (San Francisco, California) |
| ABSTRACT | Disclosed herein, inter alia, are compositions and methods for modulating Ras and treating cancer. |
| FILED | Friday, March 31, 2023 |
| APPL NO | 18/194410 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 231/14 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) C12N 9/96 (20130101) Enzymes C12Y 306/05002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077508 | Capobianco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | University of Miami (Miami, Florida) |
| INVENTOR(S) | Anthony J. Capobianco (Miami Beach, Florida); Stephan C. Schürer (Coral Gables, Florida); Xiaoxia Zhu (Palmetto Bay, Florida); Tanya T. Kelley (Miami, Florida) |
| ABSTRACT | Disclosed herein are Notch transcriptional activation complex kinase (“MACK”) inhibitors, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein include compounds of Formula (Ia) and pharmaceutically acceptable salts thereof: wherein the substituents are as described. |
| FILED | Tuesday, September 06, 2022 |
| APPL NO | 17/929957 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 231/54 (20130101) Original (OR) Class Enzymes C12Y 207/00 (20130101) C12Y 306/01003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077509 | Dong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arvinas Operations, Inc. (New Haven, Connecticut) |
| ASSIGNEE(S) | Arvinas Operations, Inc. (New Haven, Connecticut) |
| INVENTOR(S) | Hanqing Dong (Madison, Connecticut); Keith R. Hornberger (Southbury, Connecticut); Lawrence B. Snyder (Killingworth, Connecticut) |
| ABSTRACT | The present disclosure relates to bifunctional compounds, which find utility to degrade (and inhibit) Androgen Receptor. In particular, the present disclosure is directed to compounds, which contain on one end a cereblon ligand which binds to the E3 ubiquitin ligase and on the other end a moiety which binds Androgen Receptor, such that Androgen Receptor is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of Androgen Receptor. The present disclosure exhibits a broad range of pharmacological activities associated with compounds according to the present disclosure, consistent with the degradation/inhibition of Androgen Receptor. |
| FILED | Thursday, June 22, 2023 |
| APPL NO | 18/213055 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/02 (20130101) A61K 31/166 (20130101) A61K 31/277 (20130101) A61K 31/496 (20130101) A61K 31/497 (20130101) A61K 31/501 (20130101) A61K 31/506 (20130101) A61K 45/06 (20130101) A61K 47/10 (20130101) Heterocyclic Compounds C07D 205/04 (20130101) C07D 209/48 (20130101) C07D 211/76 (20130101) C07D 213/72 (20130101) C07D 221/20 (20130101) C07D 231/12 (20130101) C07D 233/42 (20130101) Original (OR) Class C07D 237/08 (20130101) C07D 239/24 (20130101) C07D 241/04 (20130101) C07D 401/04 (20130101) C07D 401/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
12077512 — Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
| US 12077512 | Ginty et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David D. Ginty (Cambridge, Massachusetts); Lauren L. Orefice (Cambridge, Massachusetts); Jinbo Lee (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides novel peripherally-restricted benzodiazepines with reduced blood brain barrier permeability and methods of use thereof for reducing tactile dysfunction, social impairment, and anxiety in a subject diagnosed with Autism Spectrum Disorder, Rett syndrome, Phelan McDermid syndrome, or Fragile X syndrome. |
| FILED | Wednesday, March 25, 2020 |
| APPL NO | 17/442474 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 243/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077527 | Mews et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Pennsylvania, Pennsylvania) |
| INVENTOR(S) | Philipp Mews (New York, New York); Shelley L Berger (Wayne, Pennsylvania); Jeffrey D. Winkler (Wynnewood, Pennsylvania); Andrew Glass (Philadelphia, Pennsylvania); Simon David Peter Baugh (Ringoes, New Jersey) |
| ABSTRACT | The present invention provides compositions and methods for inhibiting ACSS2 for modulating histone acetylation or for treating or preventing a neurological disease or disorder. |
| FILED | Wednesday, September 26, 2018 |
| APPL NO | 16/650901 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Heterocyclic Compounds C07D 409/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077557 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Christopher J. Chang (Berkeley, California); Yik Sham Clive Chung (Berkeley, California) |
| ABSTRACT | The present disclosure provides puromycin-based probes, as well as compositions and kits comprising the probes. The present disclosure provides methods of detecting an analyte, and imaging methods, using the probes. |
| FILED | Wednesday, March 20, 2019 |
| APPL NO | 16/981511 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/16 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077572 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Korea (Center for Disease Control and Prevention) (Chungcheongbuk-do, South Korea) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); KOREA (CENTER FOR DISEASE CONTROL AND PREVENTION) (Chungcheongbuk-do, South Korea) |
| INVENTOR(S) | Hansaem Lee (Chungcheongbuk-do, South Korea); Janghoon Choi (Chungcheongbuk-do, South Korea); Sungsoon Kim (Chungcheongbuk-do, South Korea); Lingshu Wang (Bethesda, Maryland); Barney Graham (Bethesda, Maryland); John R Mascola (Bethesda, Maryland) |
| ABSTRACT | The present invention relates to monoclonal antibodies for a spike protein of the Middle East respiratory syndrome coronavirus (MERS-CoV), and a use thereof. Particularly, monoclonal antibodies 77-A5, 77-A6, 90-A3, 90-A9, 90-B2, 90-B7, 90-C4, 90-E5, 90-E6, 90-F1 and 90-F2 according to the present invention have excellent attachment force with respect to a full-length spike protein of MERS-CoV and the S1 domain of the protein, and, of the monoclonal antibodies, the monoclonal antibodies 90-F1, 90-E5, 90-E6, 90-F2, 77-A5 and 77-A6 have excellent attachment force with respect to an RBD antigen of MERS-CoV. Also, the antibodies 77-A5, 77-A6, 90-E5, 90-E6, 90-F1 and 90-F2 exhibit neutralizing capacity with respect to a MERS pseudovirus and MERS-CoV, and the antibodies 90-B2 and 90-B7 exhibit neutralizing capacity only with respect to MERS-CoV. Further, the monoclonal antibodies have a particular monomeric form, and have excellent stability and thus may be useful for treating or diagnosing MERS. |
| FILED | Sunday, September 25, 2022 |
| APPL NO | 17/952308 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/565 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077573 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Patrick Wilson (Chicago, Illinois); Yaoqing Chen (Chicago, Illinois); Haley L. Dugan (Chicago, Illinois) |
| ABSTRACT | Provided herein are anti-neuraminidase agents useful for neutralization of influenza virus infection, and methods of use and manufacture thereof. In particular, compositions comprising anti-neuraminidase agents (e.g., antibodies) that are cross-reactive with multiple influenza strains are provided, as well as methods of treatment and prevention of influenza infection therewith. |
| FILED | Thursday, June 15, 2023 |
| APPL NO | 18/335869 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077574 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Patrick Wilson (Chicago, Illinois); Yaoqing Chen (Chicago, Illinois); Haley L. Dugan (Chicago, Illinois) |
| ABSTRACT | Provided herein are anti-neuraminidase agents useful for neutralization of influenza virus infection, and methods of use and manufacture thereof. In particular, compositions comprising anti-neuraminidase agents (e.g., antibodies) that are cross-reactive with multiple influenza strains are provided, as well as methods of treatment and prevention of influenza infection therewith. |
| FILED | Thursday, June 15, 2023 |
| APPL NO | 18/335876 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077575 | Feng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hanping Feng (Ellicott City, Maryland); Yongrong Zhang (Columbia, Maryland); Zhiyong Yang (West Friendship, Maryland); Hua Yu (Columbia, Maryland); Yifan Zhang (North Potomac, Maryland) |
| ASSIGNEE(S) | FZATA, INC. (Halethorpe, Maryland); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Hanping Feng (Ellicott City, Maryland); Yongrong Zhang (Columbia, Maryland); Zhiyong Yang (West Friendship, Maryland); Hua Yu (Columbia, Maryland); Yifan Zhang (North Potomac, Maryland) |
| ABSTRACT | Novel, antibody-based binding agents derived from camelid VHH and human immunoglobulins are described. These binding agents recognize and bind with specificity to Clostridium difficile toxin A and/or toxin B and in some cases exhibit toxin neutralizing activity. These binding agents can be used to treat or prevent primary and recurrent CDI. The binding agents include humanized VHH peptide monomers, linked groups of humanized VHH peptide monomers, humanized VHH peptide monomers joined to antibody Fc domains, and humanized VHH peptide monomers joined to IgG antibodies. |
| FILED | Wednesday, June 03, 2020 |
| APPL NO | 17/616134 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 16/1282 (20130101) Original (OR) Class C07K 2317/22 (20130101) C07K 2317/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077609 | Shusta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); EMORY UNIVERSITY (Atlanta, Georgia) |
| INVENTOR(S) | Eric V. Shusta (Madison, Wisconsin); Benjamin Umlauf (Madison, Wisconsin); Brantley Herrin (Atlanta, Georgia); Paul Clark (Madison, Wisconsin); John Kuo (Austin, Texas) |
| ABSTRACT | The present disclosure provides isolated polypeptides comprising variable lymphocyte receptors that specifically bind the brain extracellular matrix, compositions, and methods of use. Methods of using the variable lymphocyte receptors for the detection and treatment of disease or injury, specifically, for example, cancers including glioblastoma are provided. |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 17/414581 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077610 | Bhattacharjee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Amherst, New York) |
| INVENTOR(S) | Arindam Bhattacharjee (Buffalo, New York); Kerri Pryce (Amherst, New York) |
| ABSTRACT | Described herein are peptides that can be used to treat pain or increase pain sensitivity in subject in need of treatment. Additionally, peptides of the present disclosure can be administered with an analgesic agent and/or anesthetic agent. Peptides of the present disclosure are suitable for use when a subject in need of treatment has an injury, a chronic disease, a chronic inflammation, Morton's neuroma, operative/post-operative pain, or a combination thereof. |
| FILED | Thursday, September 29, 2022 |
| APPL NO | 17/956031 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/45 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Peptides C07K 7/08 (20130101) Original (OR) Class Enzymes C12Y 207/04008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077621 | Appel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior Univeristy (Stanford, California) |
| INVENTOR(S) | Eric A. Appel (Palo Alto, California); Caitlin Maikawa (Boston, Massachusetts); Joseph L. Mann (Mountain View, California) |
| ABSTRACT | A polyacrylamide-based copolymer reduces or prevents aggregation of biologic molecules including proteins, peptides, and nucleic acids, and lipid-based vehicles such as liposomes, lipid nanoparticles, polymerosomes, and micelles, in aqueous formulations at hydrophobic interfaces, thereby increasing the thermal stability of the molecules in the formulation. Methods and compositions comprising the copolymer and a protein or the copolymer and insulin can be used for treating conditions including diabetes. |
| FILED | Tuesday, October 17, 2023 |
| APPL NO | 18/381125 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) A61K 9/5146 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/36 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077638 | Oakey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Wyoming (Laramie, Wyoming) |
| ASSIGNEE(S) | University of Wyoming (Laramie, Wyoming) |
| INVENTOR(S) | John Oakey (Laramie, Wyoming); Kaspars Krutkramelis (Laramie, Wyoming); Bingzhao Xia (Calamvale, Australia) |
| ABSTRACT | Provided herein are methods utilizing microfluidics for the oxygen-controlled generation of microparticles and hydrogels having controlled microparticle sizes and size distributions and products from provided methods. The included methods provide the generation of microparticles by polymerizing an aqueous solution dispersed in a non-aqueous continuous phase in an oxygen-controlled environment. The process allows for control of size of the size of the aqueous droplets and, thus, control of the size of the generated microparticles which may be used in biological applications. |
| FILED | Wednesday, October 26, 2016 |
| APPL NO | 15/335184 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5026 (20130101) A61K 35/12 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) A61L 27/18 (20130101) A61L 27/38 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 23/41 (20220101) B01F 25/4331 (20220101) B01F 33/3011 (20220101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2/06 (20130101) B01J 13/0052 (20130101) B01J 19/0093 (20130101) B01J 2219/00792 (20130101) B01J 2219/00936 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/32 (20130101) C08F 2/48 (20130101) C08F 216/125 (20130101) C08F 222/102 (20200201) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) Original (OR) Class C08J 9/26 (20130101) C08J 2201/046 (20130101) C08J 2205/022 (20130101) C08J 2207/10 (20130101) C08J 2335/02 (20130101) C08J 2345/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077741 | Slater et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John H. Slater (Landenberg, Pennsylvania); Shantanu Pradhan (Chennai, India); Cindy Jazmin Farino Reyes (Claymont, Delaware) |
| ASSIGNEE(S) | University Of Delaware (Newark, Delaware) |
| INVENTOR(S) | John H. Slater (Landenberg, Pennsylvania); Shantanu Pradhan (Chennai, India); Cindy Jazmin Farino Reyes (Claymont, Delaware) |
| ABSTRACT | The present invention discloses crosslinked poly(alkylene glycol) (PAG)-based hydrogel compositions, systems containing a plurality of cancer cells in contact with a cell culture media and encapsulated in the crosslinked PAG-based hydrogel composition and methods of making such crosslinked hydrogel compositions and systems. Also disclosed herein are methods of using such compositions and systems, such as, for example for screening an agent for effectiveness of the agent against cancer cells. Also disclosed herein are kits containing one or more components including one or more systems of the present disclosure and one or more instructions. |
| FILED | Thursday, June 04, 2020 |
| APPL NO | 16/893330 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Peptides C07K 5/1019 (20130101) C07K 5/1021 (20130101) C07K 7/06 (20130101) C07K 7/08 (20130101) Apparatus for Enzymology or Microbiology; C12M 25/00 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 2503/00 (20130101) C12N 2533/40 (20130101) C12N 2533/50 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 21/6428 (20130101) G01N 33/5011 (20130101) G01N 33/5091 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077755 | Khvorova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Mehran Nikan (Boston, Massachusetts); Matthew Hassler (Worcester, Massachusetts); Maire Osborn (Boston, Massachusetts); Reka Haraszti (Boston, Massachusetts); Andrew Coles (Boston, Massachusetts); Anton Turanov (Boston, Massachusetts); Neil Aronin (Newtonville, Massachusetts) |
| ABSTRACT | Provided herein are self-delivering oligonucleotides that are characterized by efficient RISC entry, minimum immune response and off-target effects, efficient cellular uptake without formulation, and efficient and specific tissue distribution. |
| FILED | Monday, March 09, 2020 |
| APPL NO | 16/812714 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/61 (20170801) A61K 47/542 (20170801) A61K 47/554 (20170801) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/3515 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077760 | Lopez-Berestein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas); Consiglio Nazionale delle Ricerche (Rome, Italy) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas); Consiglio Nazionale delle Ricerche (Rome, Italy) |
| INVENTOR(S) | Gabriel Lopez-Berestein (Houston, Texas); Paola Amero (Houston, Texas); Cristian Rodriguez-Aguayo (Houston, Texas); Rahul Mitra (Houston, Texas); Anil K. Sood (Houston, Texas); Vittorio De Franciscis (Naples, Italy); David Volk (Houston, Texas); Lokesh Ganesh L. Rao (Houston, Texas) |
| ABSTRACT | Provided herein are DNA aptamers targeting AXL receptor kinase. The DNA aptamers may comprise a thiophosphate backbone and be chemically modified. Further provided herein are methods of use thereof for the treatment of a disease or disorder, such as cancer. |
| FILED | Monday, December 16, 2019 |
| APPL NO | 17/413550 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 33/243 (20190101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2310/313 (20130101) C12N 2310/322 (20130101) C12N 2310/351 (20130101) C12N 2310/531 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077761 | Valdivia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Raphael Valdivia (Durham, North Carolina); Per Malkus (Durham, North Carolina); Lauren Davey (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides methods and systems for genetically altering and screening Akkermansia bacteria, including Akkermansia muciniphila. The methods also provide genetically altered bacteria, libraries of genetically altered bacteria and use of such bacteria for treatment of diseases. |
| FILED | Wednesday, May 15, 2019 |
| APPL NO | 17/055478 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 15/74 (20130101) Original (OR) Class C12N 15/1079 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077776 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ying Zhang (Shijiazhuang, China PRC); Julia Xiaojun Zhao (Grand Forks, North Dakota); Diane Darland (Grand Forks, North Dakota) |
| ASSIGNEE(S) | UNIVERSITY OF NORTH DAKOTA (Grand Forks, North Dakota) |
| INVENTOR(S) | Ying Zhang (Shijiazhuang, China PRC); Julia Xiaojun Zhao (Grand Forks, North Dakota); Diane Darland (Grand Forks, North Dakota) |
| ABSTRACT | A method of making a porous three-dimensional graphene mesh includes combining a graphene-containing material and a polymer having a plurality of hydroxyl groups in an alcohol solvent to form a mixture, adding a salt to the mixture, heating the mixture to form a gel, and washing the gel with water to remove the salt from the gel, leaving behind stable pores to form a scaffold. A three-dimensional porous graphene mesh includes a graphene-containing material and a polymer. The polymer is crosslinked with the graphene-containing material such that the Young's Modulus of the mesh is at least about 5 GPa. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/214195 |
| ART UNIT | 1699 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0068 (20130101) Original (OR) Class C12N 2533/40 (20130101) C12N 2537/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077778 | Koehler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Indianapolis, Indiana) |
| ASSIGNEE(S) | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (Bloomington, Indiana) |
| INVENTOR(S) | Karl R. Koehler (Indianapolis, Indiana); Eri Hashino (Indianapolis, Indiana) |
| ABSTRACT | Provided herein are methods for directing differentiation of human pluripotent stem cells into inner ear sensory epithelia and sensory neurons. More particularly, provided herein are methods for obtaining three-dimensional cultures comprising human pluripotent stem cell-derived pre-otic epithelium, otic vesicles, and inner ear sensory epithelia containing hair cells, sensory neurons, and supporting cells. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/989554 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/062 (20130101) Original (OR) Class C12N 5/0606 (20130101) C12N 5/0607 (20130101) C12N 2501/15 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2501/415 (20130101) C12N 2506/02 (20130101) C12N 2533/52 (20130101) C12N 2533/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077793 | Ernst et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland); University of Washington (Seattle, Washington) |
| INVENTOR(S) | Robert K. Ernst (Silver Spring, Maryland); Mark Pelletier (Brunswick, Maryland); Adeline Hajjar (Seattle, Washington) |
| ABSTRACT | Embodiments of the disclosure provide for unique lipooligosaccharide/lipid A-based mimetics for use as adjuvants. Methods of generating lipooligosaccharide/lipid A-based mimetics are provided that utilize recombinantly engineered bacteria to produce the mimetics, including, for example, addition of one or more particular enzymes such as acyltransferases, deacylases, phosphatases, or glycosyltransferases. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 17/445708 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/739 (20130101) A61K 39/39 (20130101) A61K 39/099 (20130101) A61K 39/0291 (20130101) A61K 2039/55572 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 11/04 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/12 (20130101) Original (OR) Class C12P 19/26 (20130101) C12P 19/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077811 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David Yu Zhang (Cambridge, Massachusetts); Peng Yin (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are primers and primer systems having improved specificity and kinetics over existing primers, and methods of use thereof. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/169145 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6853 (20130101) Original (OR) Class C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2537/161 (20130101) C12Q 2537/161 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077821 | Sadhasivam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (, None) |
| INVENTOR(S) | Senthilkumar Sadhasivam (Mason, Ohio); Vidya Chidambaran (Cincinnati, Ohio); John McAuliffe (Cincinnati, Ohio); Kejian Zhang (Cincinnati, Ohio); Jaroslaw Meller (Cincinnati, Ohio); Cynthia A. Prows (Cincinnati, Ohio); Tsuyoshi Fukuda (Cincinnati, Ohio) |
| ABSTRACT | Methods and compositions disclosed herein generally relate to methods of improving clinical and economic outcomes to address adverse effects related to anesthesia, analgesics, opioids, and inadequate pain relief. Embodiments of the invention relate to the association between genes, specific polymorphisms of genes, and non-genetic factors with inadequate pain relief and anesthesia-, analgesic, and/or opioid-related adverse effects. Embodiments of the invention can be used to determine and manage patient risk factors for development of adverse perioperative effects and can allow for personalized anesthesia and pain management for improvement of pain control and reduction of anesthesia-, analgesic-, and opioid-related adverse outcomes. These methods and compositions apply to non-surgical pain management with opioids. Therefore, patients who are genetically predisposed to risk of inadequate pain relief and/or serious side effects from anesthesia, analgesics, and/or opioids can be identified and individualized treatment plans developed for implementation by the clinician to improve clinical and economic outcomes. |
| FILED | Friday, June 19, 2020 |
| APPL NO | 16/946399 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077826 | Gartner et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of The University of California (, None) |
| INVENTOR(S) | Zev J. Gartner (San Francisco, California); David Patterson (San Francisco, California); Eric D. Chow (San Francisco, California); Robert Weber (San Francisco, California); Christopher McGinnis (San Francisco, California) |
| ABSTRACT | Disclosed are compositions comprising a first lipid-conjugated oligonucleotide comprising a first lipid moiety, a first hybridization region, and a first primer region; a second lipid-conjugated oligonucleotide comprising a second hybridization region and a second lipid moiety, wherein the second hybridization region is the reverse complement of the first hybridization region; and a third oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region; compositions comprising a lipid-conjugated DNA oligonucleotide comprising a lipid moiety, a barcode region, and a capture sequence; and composition comprising a first lipid-conjugated DNA oligonucleotide comprising a lipid moiety and a first primer region; and a second DNA oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region. Also disclosed are membranes and cells comprising such compositions and uses of such compositions. |
| FILED | Monday, July 08, 2019 |
| APPL NO | 17/258420 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077846 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (, None) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | David Anderson (Nashville, Tennessee); Eric Spivey (Nashville, Tennessee); Richard Caprioli (Nashville, Tennessee) |
| ABSTRACT | This disclosure relates to apparatus and methods for sublimation and deposition of chemicals. In particular aspects, this disclosure relates to apparatus and methods for patterned sublimation and deposition of chemicals for use in matrix assisted laser desorption ionization imaging mass spectrometry (MALDI IMS). In specific aspects, the apparatus comprises a vacuum chamber and a template comprising a planar surface containing the chemical to be sublimed, where the template is located within the vacuum chamber. |
| FILED | Wednesday, November 27, 2019 |
| APPL NO | 16/698311 |
| ART UNIT | 1718 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/04 (20130101) C23C 14/24 (20130101) Original (OR) Class C23C 14/50 (20130101) C23C 14/243 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078578 | Suki et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University, Boston (MA) (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Bela Suki (Newton, Massachusetts); Jae Hun Kim (Natick, Massachusetts); Joseph Hall (Boston, Massachusetts); Ramaswamy Krishnan (Boston, Massachusetts); Niccole Schaible (Boston, Massachusetts) |
| ABSTRACT | Provided herein are systems for determining a stretch condition of a tissue and assessing the stiffness of the tissue. Also provided herein are methods for using the systems for measuring stiffness of a tissue, assessing the effect of an agent on a tissue, and identifying subjects having a disease or disorder associated with increased or decreased stiffness of a tissue. |
| FILED | Friday, June 16, 2023 |
| APPL NO | 18/211046 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/06 (20130101) Original (OR) Class G01N 1/312 (20130101) G01N 3/08 (20130101) G01N 35/00009 (20130101) G01N 2035/00019 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078588 | Haghgooie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Ramin Haghgooie (Arlington, Arkansas); Kenneth T. Kotz (Auburndale, Massachusetts); Robert Granier (Boston, Massachusetts); Anne Celia Petrofsky (Sudbury, Massachusetts) |
| ABSTRACT | Reusable network of spatially-multiplexed microfluidic channels each including an inlet, an outlet, and a cuvette in-between. Individual channels may operationally share a main or common output channel defining the network output and optionally leading to a disposable storage volume. Alternatively, multiple channels are structured to individually lead to the storage volume. An individual cuvette is dimensioned to substantially prevent the formation of air-bubbles during the fluid sample flow through the cuvette and, therefore, to be fully filled and fully emptied. The overall channel network is configured to spatially lock the fluidic sample by pressing such sample with a second fluid against a closed to substantially immobilize it to prevent drifting due to the change in ambient conditions during the measurement. Thereafter, the fluidic sample is flushed through the now-opened valve with continually-applied pressure of the second fluid. System and method for photometric measurements of multiple fluid samples employing such network of channels. |
| FILED | Wednesday, April 19, 2023 |
| APPL NO | 18/303073 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502723 (20130101) B01L 2200/143 (20130101) B01L 2200/146 (20130101) B01L 2300/0851 (20130101) B01L 2300/0858 (20130101) B01L 2300/0877 (20130101) B01L 2400/0622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/03 (20130101) Original (OR) Class G01N 21/11 (20130101) G01N 21/253 (20130101) G01N 2021/0346 (20130101) G01N 2021/0357 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078612 | Kijanka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Piotr Kijanka (Rochester, Minnesota); Matthew W. Urban (Rochester, Minnesota) |
| ABSTRACT | Described here are systems and methods for phase velocity imaging using an imaging system, such as an ultrasound system, an optical imaging system (e.g., an optical coherence tomography system), or a magnetic resonance imaging system. In general, systems and methods for constructing phase velocity images (e.g., 2D images, 3D images) from propagating mechanical wave motion data are described. The systems and methods described in the present disclosure operate in the frequency domain and can be implemented using a single frequency or a band of selected frequencies. If there are multiple mechanical wave sources within the field-of-view, directional filtering may be performed to separate mechanical waves propagating in different directions. The reconstructions described below can be performed for each of these directionally filtered components. |
| FILED | Wednesday, August 28, 2019 |
| APPL NO | 17/282569 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7257 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/46 (20130101) G01N 29/075 (20130101) Original (OR) Class G01N 29/0672 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/53 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078625 | van Dam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | R. Michael van Dam (Sherman Oaks, California); Jia Wang (Los Angeles, California); Alejandra Rios (Los Angeles, California) |
| ABSTRACT | A method of performing high-throughput radio thin layer chromatography (radio-TLC) includes spotting a plurality of locations on one or more TLC plates with samples containing a radiochemical or a radiopharmaceutical, each location defining an individual lane on the one or more TLC plates for the respective samples. The one or more TLC plates are developed with a developing solution and dried. The TLC plates are imaged with an imaging device comprising a camera, wherein the image obtained from the camera comprises a field of view that contains regions of interest (ROIs) from the plurality of lanes. The ROIs in the images obtained from the camera may then be analyzed by the user. The ROIs may be used, for example, reaction optimization or for quality control check of the production of radiotracers. |
| FILED | Wednesday, April 15, 2020 |
| APPL NO | 17/605213 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/95 (20130101) Original (OR) Class G01N 35/10 (20130101) Pictorial Communication, e.g Television H04N 25/71 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078639 | Lim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AmberGen, Inc. (Watertown, Massachusetts) |
| ASSIGNEE(S) | AmberGen, INC. (Billerica, Massachusetts) |
| INVENTOR(S) | Mark J. Lim (Reading, Massachusetts); Gargey Yagnik (Hopkinton, Massachusetts); Kenneth J. Rothschild (Newton, Massachusetts) |
| ABSTRACT | The field of this invention relates to immunohistochemistry (IHC) and in situ hybridization (ISH) for the targeted detection and mapping of biomolecules (e.g., proteins and miRNAs) in tissues or cells for example, for research use and for clinical use such by pathologists (e.g., biomarker analyses of a resected tumor or tumor biopsy). In particular, the use of mass spectrometric imaging (MSI) as a mode to detect and map the biomolecules in tissues or cells for example. More specifically, the field of this invention relates to photocleavable mass-tag reagents which are attached to probes such as antibodies and nucleic acids and used to achieve multiplex immunohistochemistry and in situ hybridization, with MSI as the mode of detection/readout. Probe types other than antibodies and nucleic acids are also covered in the field of invention, including but not limited to carbohydrate-binding proteins (e.g., lectins), receptors and ligands. Finally, the field of the invention also encompasses multi-omic MSI procedures, where MSI of photocleavable mass-tag probes is combined with other modes of MSI, such as direct label-free MSI of endogenous biomolecules from the biospecimen (e.g., tissue), whereby said biomolecules can be intact or digested (e.g., chemically digested or by enzyme). |
| FILED | Wednesday, July 13, 2022 |
| APPL NO | 17/863928 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 271/20 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6851 (20130101) Original (OR) Class G01N 2400/00 (20130101) G01N 2458/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078640 | Kesimer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Mehmet Kesimer (Carrboro, North Carolina) |
| ABSTRACT | The present invention is directed to the use of (1) mucin concentration in sputum; (2) individual airway mucins MUC5AC and MUC5B ratio (MUC5AC/MUC5B) in sputum; and (3) combination of both measurements (Kesimer MUCQuant index) that can be used as an objective biomarker for differential diagnosis of smoking status and chronic bronchitis (CB), disease severity of CB (mild, moderate, and severe), exacerbation status, monitoring progression of CB, and guiding of therapies for CB. In addition, the ratio of amount of IgGFc-binding protein (FCGBP) and the amount of bactericidal/permeability-increasing fold-containing family member A1 (BPIFA1 (or SPLUNC1)) present in a sputum sample from a subject may be used in combination with the Kesimer MUCQuant index (Kesimer MUCQuant Plus index) for differential diagnosis of smoking status and CB, disease severity of CB, exacerbation status, p monitoring progression of CB, and guiding of therapies for CB. |
| FILED | Thursday, May 03, 2018 |
| APPL NO | 16/609282 |
| ART UNIT | 1671 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2333/4725 (20130101) G01N 2800/00 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/60 (20130101) G01N 2800/122 (20130101) G01N 2800/127 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078646 | Ge et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (, None) |
| INVENTOR(S) | Ying Ge (Madison, Wisconsin); Song Jin (Madison, Wisconsin); Kyle Brown (Madison, Wisconsin); Kevin Buck (Madison, Wisconsin) |
| ABSTRACT | Exosomes are a small type of extracellular vesicles containing nucleic acids, lipids, and proteins that are implicated in tumorigenesis, metastasis, and cardiac regeneration, and therefore serve as potentially useful biomarkers from fluids or as vehicles for drug delivery. Global bottom-up mass spectrometry-based proteomics has been previously used to profile exosome cargo for diagnostic purposes. However, the current protocols for MS analysis of extracellular vesicles and exosome proteomics are challenging due to labor-intensive sample preparation, including lengthy digestion times and removal of MS incompatible reagents, and the need for high sensitivity. To address these challenges, the present invention provides a novel, high-throughput strategy for extracellular vesicle analysis and exosome proteomics using a photo-cleavable, anionic surfactant, preferably 4-hexylphenylazosulfonate (Azo). These photo-cleavable, anionic surfactants are able to facilitate high-throughput digestion with minimal sample cleanup for quantitative and highly reproducible analysis. |
| FILED | Tuesday, November 01, 2022 |
| APPL NO | 17/978793 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Detergent Compositions; Use of Single Substances as Detergents; Soap or Soap-making; Resin Soaps; Recovery of Glycerol C11D 1/143 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/33 (20130101) G01N 33/52 (20130101) G01N 33/92 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078700 | Tang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Xueyan Tang (Minneapolis, Minnesota); Michael Garwood (Minneapolis, Minnesota); Steven Suddarth (Minneapolis, Minnesota) |
| ABSTRACT | Spin resonance spectroscopy and/or imaging is achieved using a system that combines longitudinal (e.g., along the z-axis) detection with a modulated fictitious field generated by a transverse plane (e.g., xy-plane) RF field. Based on z-axis detection of magnetization polarized by this fictitious field as it is modulated (e.g., modulated on and off, or otherwise), spin resonance signals (e.g., EPR, NMR) are measurable with high isolation simultaneous transmit and receive capability. Additionally or alternatively, spin relaxation times can be measured using the described systems. |
| FILED | Tuesday, March 08, 2022 |
| APPL NO | 17/689794 |
| ART UNIT | 3798 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/46 (20130101) Original (OR) Class G01R 33/60 (20130101) G01R 33/385 (20130101) G01R 33/34092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079960 | Clark et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TERRAN BIOSCIENCES INC. (New York, New York); THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York); THE RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC. (Menands, New York) |
| ASSIGNEE(S) | Terran Biosciences Inc. (Miami Beach, Florida); The Trustees of Columbia University in the City of New York (New York, New York); The Research Foundation for Mental Hygiene, Inc. (Menands, New York) |
| INVENTOR(S) | Samuel Clark (New York, New York); Kenneth Wengler (New York, New York); Guillermo Horga Hernandez (New York, New York) |
| ABSTRACT | An exemplary system, method and computer-accessible medium for harmonizing neuromelanin (NM) data using combat directly on a NM database or using combat generated coefficients to harmonize future data can include, for example, receiving imaging information of a brain of the patient(s), from one MRI scanner, receiving imaging information of a brain of the patient(s), from a second MRI scanner and using combat to harmonize the data between scanners against a reference dataset. The Neuromelanin (NM) concentration of the patient(s) can then be determined based on the harmonized data. The NM concentration can be determined using a voxel-wise analysis procedure. The voxel-wise analysis procedure can be used to determine a topographical pattern(s) within a substantia nigra (SN) of the brain of the patient(s). |
| FILED | Friday, March 11, 2022 |
| APPL NO | 17/693166 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Image Data Processing or Generation, in General G06T 5/50 (20130101) Original (OR) Class G06T 5/90 (20240101) G06T 7/0014 (20130101) G06T 2207/10088 (20130101) G06T 2207/20081 (20130101) G06T 2207/30016 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080052 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Leland S. Hu (Phoenix, Arizona); Kristin R. Swanson (Phoenix, Arizona); J. Ross Mitchell (Tampa, Florida); Nhan L. Tran (Peoria, Arizona); Jing Li (Marietta, Georgia); Teresa Wu (Gilbert, Arizona) |
| ABSTRACT | Methods that implement image-guided tissue analysis, MRI-based computational modeling, and imaging informatics to analyze the diversity and dynamics of molecularly-distinct subpopulations and the evolving competitive landscapes in human glioblastoma multiforme (“GBM”) are provided. Machine learning models are constructed based on multiparametric MRI data and molecular data (e.g., CNV, exome, gene expression). Models can also be built based on specific biological factors, such as sex and age. Inputting MRI data into the trained predictive models generates maps that depict spatial patterns of molecular markers, which can be used to quantify and co-localize regions molecularly distinct subpopulations in tumors and other regions, such as the non-enhancing parenchyma, or brain around tumor (“BAT”) regions. |
| FILED | Friday, May 20, 2022 |
| APPL NO | 17/749775 |
| ART UNIT | 2672 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0016 (20130101) G06T 2207/10088 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30016 (20130101) G06T 2207/30096 (20130101) Image or Video Recognition or Understanding G06V 10/776 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080404 | Buckland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Translational Imaging Innovations, Inc. (Hickory, North Carolina) |
| ASSIGNEE(S) | Translational Imaging Innovations, Inc. (Hickory, North Carolina) |
| INVENTOR(S) | Eric L. Buckland (Hickory, North Carolina); Joseph Carroll (New Berlin, Wisconsin); Robert C. Williams (Durham, North Carolina); Andrew J. Witchger, Jr. (Durham, North Carolina) |
| ABSTRACT | Integrated systems for collecting, storing, and distribution of images acquired of subjects in a research or clinical environment are provided. The system includes an image and data repository including a plurality of images originating from one or more image-generating devices, data associated with the images, and data associated with imaged subjects; and a workflow management module in direct communication with the image and data repository and with the one or more image-generating devices and/or storage devices that store the images of the imaged subjects, the workflow management module being configured to transport the images directly from the one or more image-generating devices and/or storage devices to the image and data repository and to manage the collation and distribution of images, data associated with the raw images and the data associated with the imaged subjects in the image and data repository. The workflow management module includes a data integration module, a data management module, a pre-processing engine and a data utilization module. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/839475 |
| ART UNIT | 2492 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) G06F 11/3476 (20130101) G06F 21/6218 (20130101) G06F 2221/2141 (20130101) Image Data Processing or Generation, in General G06T 7/20 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080426 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Qing Lu (Gainesville, Florida); Shan Zhang (Gainesville, Florida); Tingting Hou (Gainesville, Florida) |
| ABSTRACT | Various examples of methods and systems are provided related to functional deep neural networks (FDNNs), which can be used for high dimensional data analysis. In one example, a FDNN can be trained with a training set of omic data to produce a trained FDNN model. The likelihood of a condition can be determined based upon output indications of the FDNN corresponding to the one or more phenotypes, with the output indications based upon analysis of omic data including a multi-level omic profile from an individual by the trained FDNN. The FDNN model can include a series of basis functions as layers to capture complexity between the omic data with disease phenotypes. A treatment or prevention strategy for the individual can be identified based at least in part upon the likelihood of the condition. |
| FILED | Tuesday, March 30, 2021 |
| APPL NO | 17/217082 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30016 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/20 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080432 | Johnson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Lawrence Cody Johnson (Broomfield, Colorado); Christopher R. Martens (Kennett Square, Pennsylvania); Douglas R. Seals (Boulder, Colorado); Keli Parker (Ann Arbor, Michigan) |
| ABSTRACT | Chronological age is an important predictor of morbidity and mortality, however it is unable to account for heterogeneity in the decline of physiological function and health with advancing age. Several attempts have been made to instead define a “biological age” using multiple physiological parameters in order to account for variation in the trajectory of human aging; however, these methods require technical expertise and are likely too time-intensive and costly to be implemented into clinical practice. Accordingly, a metabolomic signature of biological aging was developed that can predict changes in physiological function with the convenience of a blood sample. A weighted model of biological age was generated based on multiple clinical and physiological measures in a large group of healthy adults and was then applied to a cohort of healthy older adults who were tracked longitudinally over a 5-10 year timeframe. Plasma metabolomic signatures were identified that were associated with biological age, including some that could predict whether individuals would age at a faster or slower rate. These results not only have clinical implications by providing a simple blood-based assay of biological aging, but also provide insight into the molecular mechanisms underlying human healthspan. |
| FILED | Friday, June 01, 2018 |
| APPL NO | 15/995966 |
| ART UNIT | 1671 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 40/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) G16H 50/30 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12075860 | Pare |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oceanit Laboratories, Inc. (Honolulu, Hawaii) |
| ASSIGNEE(S) | Oceanit Laboratories, Inc. (Honolulu, Hawaii) |
| INVENTOR(S) | Raviraj Pare (Kailua, Hawaii) |
| ABSTRACT | Devices, systems, and methods for cooling and/or thermoregulation are disclosed, including thermoregulatory apparel. Such thermoregulatory apparel includes a cooling vest for human users to reduce their body temperature and/or to keep their body temperature below a certain value. The cooling vest may include a plurality of tubing arranged within the four-way stretch fabric used for the vest. Coolant flows through this tubing, which is arranged so that it contacts a user's skin while the user is wearing the vest. The composition and arrangement of the tubing can be matched with the type of fabric so that both the tubing and the fabric stretch in similar ways, ensuring that the tubing stays in contact with the user's skin. Also disclosed is a cartridge with a phase change material that is configured to refresh or recharge the cooling ability of the coolant when the coolant is passed through the phase change material. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/146392 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/0053 (20130101) Original (OR) Class A41D 31/18 (20190201) A41D 2300/20 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/02 (20130101) A61F 7/0053 (20130101) Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 3/005 (20130101) F25D 2400/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076120 | Techentin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); The Government of The United States, as Represented by the Secretary of the Army (Frederick, Maryland) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); The Government of the United States, as Represented by the Secretary of the Army (Frederick, Maryland) |
| INVENTOR(S) | Robert W. Techentin (Rochester, Minnesota); Timothy B. Curry (Rochester, Minnesota); Michael J. Joyner (Rochester, Minnesota); Clifton R. Haider (Rochester, Minnesota); David R. Holmes, III (Rochester, Minnesota); Christopher L. Felton (Rochester, Minnesota); Barry K. Gilbert (Rochester, Minnesota); Charlotte Sue Van Dorn (Rochester, Minnesota); William A. Carey (Rochester, Minnesota); Victor A. Convertino (San Antonio, Texas) |
| ABSTRACT | In accordance with some embodiments, systems, methods, and media for estimating compensatory reserve and predicting hemodynamic decompensation using physiological data are provided. In some embodiments, a system for estimating compensatory reserve is provided, the system comprising: a processor programmed to: receive a blood pressure waveform of a subject; generate a first sample of the blood pressure waveform with a first duration; provide the sample as input to a trained CNN that was trained using samples of the first duration from blood pressure waveforms recorded from subjects while decreasing the subject's central blood volume, each sample being associated with a compensatory reserve metric; receive, from the trained CNN, a first compensatory reserve metric based on the first sample; and cause information indicative of remaining compensatory reserve to be presented. |
| FILED | Tuesday, July 21, 2020 |
| APPL NO | 16/934805 |
| ART UNIT | 2124 — AI & Simulation/Modeling |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0004 (20130101) A61B 5/02028 (20130101) A61B 5/02042 (20130101) Original (OR) Class A61B 5/02108 (20130101) A61B 5/02416 (20130101) A61B 5/7264 (20130101) A61B 5/7275 (20130101) Computer Systems Based on Specific Computational Models G06N 3/004 (20130101) G06N 3/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076122 | Buller |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Ft. Detrick, Maryland) |
| INVENTOR(S) | Mark J. Buller (Douglas, Massachusetts) |
| ABSTRACT | A system or a method for providing pacing guidance to an individual for a particular activity based on a physiological strain index (PSI) or an adaptive physiological strain index (aPSI). The system in at least one embodiment includes a heart rate monitor, a memory storing multiple pacing templates, a clock, an activity completion module, an output device, and a processor configured to perform multiple steps resulting in outputting pacing information to the individual. The pacing information selected in at least one embodiment is based on the individual's heart rate that provides in part a PSI or aPSI, the elapsed time for the activity, and the amount of progress through the activity. |
| FILED | Wednesday, January 25, 2023 |
| APPL NO | 18/101501 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1118 (20130101) A61B 5/02055 (20130101) Original (OR) Class A61B 5/02438 (20130101) Electric Digital Data Processing G06F 16/9017 (20190101) Computer Systems Based on Specific Computational Models G06N 5/022 (20130101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076554 | Ludwig et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Kip Ludwig (Middleton, Wisconsin); Justin Williams (Cambridge, Wisconsin); Angela Williams (Cambridge, Wisconsin); Samuel Poore (Madison, Wisconsin) |
| ABSTRACT | Electrical stimulation of specific facial and lingual nerves creates a more sustained pulsatility activity compared to stimulation of other cranial nerves. Pulsatility of arteries has intrinsic time constraints related to the time for vasodilation/constriction and time to return to baseline (TBL) after electrical stimulation which may affect the pulsatility response. Control of temporal patterning and the stimulation waveform maximizes the physiological response to cerebral pulsatility and its resulting effects on cerebral spinal fluid penetration into the brain parenchyma for a multitude of therapeutic uses including clearing misfolded proteins and/or administered pharmacological agents, diluting endogenous neurochemical concentrations within the brain, and reducing non-synaptic coupling. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/854078 |
| ART UNIT | 3796 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0432 (20130101) A61N 1/0548 (20130101) Original (OR) Class A61N 1/36025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076748 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Panama) |
| INVENTOR(S) | Xianming Dai (University Park, Pennsylvania); Birgitt M. Boschitsch (University Park, Pennsylvania); Jing Wang (University Park, Pennsylvania); Tak-Sing Wong (University Park, Pennsylvania); Nan Sun (University Park, Pennsylvania) |
| ABSTRACT | Substrates having a textured surface that can maintain or improve droplet mobility in both the Cassie and Wenzel states include a textured surface and a conformal lubricant layer thereover. The textured surface can include a plurality of raised first elements and a plurality of second elements thereon and the conformal lubricant layer over the plurality of raised first elements and covering the plurality of second elements. The plurality of raised first elements can have an average height of between 0.5 μm and 500 μm, and the plurality of second elements can have an average height of between 0.01 μm and 10 μm. Such substrates can be prepared by texturing a surface of a substrate with a plurality of raised first elements and a plurality of second elements thereon; optionally silanizing the textured surface and applying a lubricant layer over the plurality of raised first elements and between the plurality of second elements. |
| FILED | Tuesday, August 27, 2019 |
| APPL NO | 16/551895 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/00 (20130101) B05D 3/101 (20130101) B05D 5/02 (20130101) B05D 5/08 (20130101) Original (OR) Class Cleaning in General; Prevention of Fouling in General B08B 17/065 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 59/022 (20130101) B29C 2059/023 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0092 (20130101) B29K 2995/0093 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076886 | Youngblood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana) |
| INVENTOR(S) | Jeffrey Paul Youngblood (West Lafayette, Indiana); Rodney Wayne Trice (West Lafayette, Indiana); Andrew Schlup (West Lafayette, Indiana); William Costakis (West Lafayette, Indiana) |
| ABSTRACT | The present disclosure provides a transparent alumina-based plate, and a hot-pressing method to make the transparent alumina-based plate from platelet alumina. Alumina powder with a platelet morphology was hot-pressed to transparency with pre-load pressures of about 0-8 MPa, maximum temperatures of about 1750-1825° C., maximum pressures of about 2.5-80 MPa, and isothermal hold times of 1-7 hours. A novel alumina-based plate has been prepared, wherein the plate has a thickness of 2-5 mm, an in-line transmission of at least 60-75% for a light with a wavelength range of 645-2500 nm, an in-line transmission variance of <15% over the wavelength range of 645-2500 nm, and a relative density of 99.00-99.95%. |
| FILED | Tuesday, December 15, 2020 |
| APPL NO | 17/121840 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 3/025 (20130101) Original (OR) Class Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 7/027 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/20 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/115 (20130101) C04B 35/645 (20130101) C04B 35/62605 (20130101) C04B 2235/5292 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077282 | Takahashi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | USA as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Marc D. Takahashi (Cupertino, California); Brian T. Fujizawa (Santa Rosa, California); Jeffery A. Lusardi (Woodland, Washington) |
| ABSTRACT | This disclosure provides a means to implement an autonomous guidance and flight control system on a partial authority aircraft. One embodiment of the disclosure includes receiving a control command result, filtering the control command result into a low frequency component and a high frequency component, directing the low frequency component to at least one trim servomechanism and directing the high frequency component to at least one stability augmentation stabilizer servomechanism, linking outputs from the trim servomechanism and the stability augmentation stabilizer servomechanism for actuating a pilot control configured to control rotors, and actuating at least one rotor. The low frequency component includes frequencies below a break frequency and the high frequency component includes frequencies above the break frequency. The break frequency is established by rate and position of the at least one servomechanism. |
| FILED | Wednesday, April 13, 2022 |
| APPL NO | 17/719967 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 13/503 (20130101) Original (OR) Class Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 43/00 (20130101) Traffic Control Systems G08G 5/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077308 | Covington et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Charles Eric Covington (Colleyville, Texas); Chia-Wei Su (Lewisville, Texas); Darren Gregory Lang (Dallas, Texas) |
| ABSTRACT | A method of operating a multi-engine drive system of an aircraft includes driving a main rotor of the aircraft by a main engine of the multi-engine drive system at an operating speed of the main engine, operating a supplemental engine of the multi-engine drive system at approximately 80% of an operating speed of the supplemental engine, wherein, during the operating step, a clutch interoperably coupled to the supplemental engine is interoperably decoupled from the main rotor and, responsive to a command to interoperably engage the clutch, if the clutch successfully engages such that the clutch is interoperably coupled to the main rotor, providing, by the supplemental engine, power to the main rotor. |
| FILED | Thursday, April 14, 2022 |
| APPL NO | 17/721015 |
| ART UNIT | 3655 — Material and Article Handling |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 31/12 (20130101) Original (OR) Class B64D 35/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077428 | Suresh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Nanyang Technological University (Singapore, Singapore) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Nanyang Technological University (Singapore, Singapore) |
| INVENTOR(S) | Subra Suresh (Singapore, Singapore); Ming Dao (West Roxbury, Massachusetts); Ju Li (Weston, Massachusetts); Zhe Shi (Cambridge, Massachusetts) |
| ABSTRACT | Compositions and methods related to multiaxially straining defect doped materials as well as their use in electrical circuits are generally described. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 17/411707 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0062 (20130101) Original (OR) Class B81B 2201/018 (20130101) B81B 2203/051 (20130101) B81B 2203/053 (20130101) B81B 2203/056 (20130101) B81B 2203/0118 (20130101) Electric Digital Data Processing G06F 30/27 (20200101) G06F 2111/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077438 | Arnold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Michael Scott Arnold (Middleton, Wisconsin); Robert Michael Jacobberger (Evanston, Illinois); Padma Gopalan (Madison, Wisconsin); Jonathan H. Dwyer (Madison, Wisconsin) |
| ABSTRACT | Methods of transferring nanostructures from a first substrate to another substrate using a copolymer polymerized from one or more non-crosslinking monomers and one or more comonomers bearing crosslinkable groups as a transfer medium are provided. Relative to a poly(methyl methacrylate) homopolymer, the crosslinkable copolymers bond more strongly to the first substrate and, as a result, are able to transfer even very narrow nanostructures between substrates with high transfer yields. |
| FILED | Tuesday, March 23, 2021 |
| APPL NO | 17/209944 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/194 (20170801) Original (OR) Class C01B 2204/06 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/03 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 133/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077440 | Hreha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Systima Technologies, Inc. (Mukilteo, Washington) |
| ASSIGNEE(S) | Systima Technologies, Inc. (Mukilteo, Washington) |
| INVENTOR(S) | Richard D. Hreha (Centerville, Ohio); Jeffrey R. Josken (West Carrollton, Ohio) |
| ABSTRACT | Methods of making a graphitic carbon-carbon composite from thermosetting polymer resin include (a) infusing bis-Schiff base resin into a carbon fiber reinforcement to form an uncured resin embedded composite, (b) positioning the uncured resin embedded composite on a substrate under a vacuum enclosure, (c) curing the bis-Schiff base resin at a first elevated temperature under vacuum to form a polymer matrix composite, (d) heating the polymer matrix composite at a second elevated temperature under inert atmosphere to form a porous carbon-carbon composite, (e) re-infusing bis-Schiff base resin into the porous carbon-carbon composite and curing under vacuum at a third elevated temperature to generate a reinfused porous carbon-carbon composite, and (f) heating the reinfused porous carbon-carbon composite at a fourth elevated temperature under inert gas to form the graphitic carbon-carbon composite. Further, the second elevated temperature and/or at least one instance of the fourth elevated temperature is greater than 1800° C. |
| FILED | Tuesday, April 05, 2022 |
| APPL NO | 17/713381 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/205 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/10 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/243 (20210501) C08J 2387/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077461 | Knotek-Smith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America US Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES of AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Heather Marie Knotek-Smith (Vicksburg, Mississippi); David Lyman Smith (Vicksburg, Mississippi) |
| ABSTRACT | An iron containing bioreactor for treating explosive compounds and other organics in contaminated surface water is disclosed. The bioreactor can be located either on-ground or in-ground at a location across which contaminated surface water flows. In one configuration the reactor is made up of (i) indigenous microbes, (ii) acetate, (iii) a low density iron-containing bed, and contains anaerobic zones in at least one portion of the flowpath. The reactor reduces the concentration of explosive compounds to below 10 ppb and also maintains this explosive compound reduction level for a period of at least one year without replenishing the microbes or iron. |
| FILED | Saturday, September 30, 2017 |
| APPL NO | 15/721886 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/705 (20130101) C02F 3/284 (20130101) C02F 3/346 (20130101) C02F 3/2806 (20130101) Original (OR) Class C02F 3/2813 (20130101) C02F 2003/001 (20130101) C02F 2003/003 (20130101) C02F 2101/003 (20130101) C02F 2103/001 (20130101) C02F 2103/06 (20130101) C02F 2103/007 (20130101) C02F 2203/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077750 | Fu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Jinglin Fu (Tempe, Arizona); Zhao Zhao (Boston, Massachusetts); Neal Woodbury (Tempe, Arizona); Hao Yan (Chandler, Arizona) |
| ABSTRACT | The present disclosure describes a nanoparticle comprising a three dimensional DNA nanocage and a payload biological macromolecule, and methods of assembly thereof. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 16/812225 |
| ART UNIT | 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 11/04 (20130101) Original (OR) Class C12N 11/06 (20130101) C12N 11/10 (20130101) C12N 15/11 (20130101) C12N 2310/532 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077811 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David Yu Zhang (Cambridge, Massachusetts); Peng Yin (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are primers and primer systems having improved specificity and kinetics over existing primers, and methods of use thereof. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/169145 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6853 (20130101) Original (OR) Class C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2537/161 (20130101) C12Q 2537/161 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077826 | Gartner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of The University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of The University of California (, None) |
| INVENTOR(S) | Zev J. Gartner (San Francisco, California); David Patterson (San Francisco, California); Eric D. Chow (San Francisco, California); Robert Weber (San Francisco, California); Christopher McGinnis (San Francisco, California) |
| ABSTRACT | Disclosed are compositions comprising a first lipid-conjugated oligonucleotide comprising a first lipid moiety, a first hybridization region, and a first primer region; a second lipid-conjugated oligonucleotide comprising a second hybridization region and a second lipid moiety, wherein the second hybridization region is the reverse complement of the first hybridization region; and a third oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region; compositions comprising a lipid-conjugated DNA oligonucleotide comprising a lipid moiety, a barcode region, and a capture sequence; and composition comprising a first lipid-conjugated DNA oligonucleotide comprising a lipid moiety and a first primer region; and a second DNA oligonucleotide comprising a second primer region, a barcode region, and a capture sequence, wherein the second primer region is the reverse complement of the first primer region. Also disclosed are membranes and cells comprising such compositions and uses of such compositions. |
| FILED | Monday, July 08, 2019 |
| APPL NO | 17/258420 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077886 | McCord et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Marian G. McCord (Raleigh, North Carolina); Richard Michael Roe (Raleigh, North Carolina); Charles S. Apperson (Raleigh, North Carolina); Andre J. West (Raleigh, North Carolina); Emiel A. DenHartog (Raleigh, North Carolina) |
| ABSTRACT | Mosquito resistant textiles and garments are provided that demonstrate resistance to mosquito bites without the use of pesticides or chemicals. The textiles and garments provide 90% or more resistance to mosquito bite resistance. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 16/368494 |
| ART UNIT | 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Knitting D04B 1/16 (20130101) D04B 1/24 (20130101) D04B 1/102 (20130101) Original (OR) Class Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2331/02 (20130101) D10B 2331/10 (20130101) D10B 2501/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078070 | Heeter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Robert W. Heeter (Indianapolis, Indiana); Daniel E. Molnar, Jr. (Indianapolis, Indiana); Jonathan M. Rivers (Indianapolis, Indiana) |
| ABSTRACT | A fan case assembly adapted for use with a gas turbine engine includes a case at extends circumferentially at least partway about an axis of the gas turbine engine and a plurality of vanes. The case is formed to define a plenum that that extends circumferentially at least partway about the axis. The plurality of vanes are arranged in the plenum and spaced apart circumferentially about the axis. |
| FILED | Wednesday, August 16, 2023 |
| APPL NO | 18/234656 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/14 (20130101) Original (OR) Class F01D 25/24 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/36 (20130101) F05D 2270/301 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078270 | Marks |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Galen L. Marks (Oxnard, California) |
| ABSTRACT | A dual cam lever hose clamp may comprise: first and second cam lever clamps and upper and lower clamp halves. The cam lever clamps may move between a retaining position and release position. The upper and lower clamp halves may form a collar when opposing ends of the clamp halves fasten together via the cam lever clamps. The first cam lever clamp may comprise a first linkage pivotally coupled to a first end of the lower clamp half and a first cam lever pivotally coupled to the first linkage. The second cam lever clamp may comprise a second linkage pivotally coupled to a second end of the lower clamp half and a second cam lever pivotally coupled to the second linkage. The first and second cam lever clamps may comprise cam levers that cammingly engage cam locking surfaces on the upper clamp half to fasten and tighten the collar. |
| FILED | Wednesday, January 18, 2023 |
| APPL NO | 18/098468 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 23/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078436 | Curliss et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Proof Research, Inc. (Columbia Falls, Montana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Brian Curliss (Beavercreek, Ohio); Vincent Steffan Francischetti (Columbia Falls, Montana); Nicholas Elmo Jack (Kalispell, Montana) |
| ABSTRACT | An improved hybrid composite projectile barrel comprising an inner liner and an outer composite matrix, the inner liner having a breech transition region and a muzzle transition region. The breech transition region and the muzzle transition region each comprises locking features that secure the outer composite matrix to the inner liner at the transition regions. In a first embodiment, the locking features are a series of longitudinally extending ribs with notches. In a second embodiment, the locking features are a plurality of pins disposed around the circumference of the breech and muzzle transition regions. In a third embodiment, the ridges and pins are combined such that a pin extends from the top of each ridge. In each embodiment with pins, the height of the pins is preferably adjusted so that the top ends of the pins form a line that is parallel with the outer diameter of the inner liner. |
| FILED | Friday, September 09, 2022 |
| APPL NO | 17/941837 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 21/04 (20130101) Original (OR) Class F41A 21/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078458 | Rackers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Arlington, Virginia) |
| ASSIGNEE(S) | The Boeing Company (Arlington, Virginia) |
| INVENTOR(S) | Keith G. Rackers (Florissant, Missouri); David T. Fischer (St. Charles, Missouri) |
| ABSTRACT | A fin deployment system for a projectile positioned in a chamber, the fin deployment system including a non-rotatable hinge pin shaft, a fin member, and a unidirectional ratchet collar member. The non-rotatable hinge pin shaft, which is coupled to the shell, defines a helically-oriented pathway. The fin member has a fin lug that couples the fin member on the hinge pin shaft for simultaneous axial and rotational movement along the helically-oriented pathway to a deployed position at an aft region of the projectile. Such movement is induced at least partially by application of a centripetal load and aerodynamic load as the projectile rotates upon launch from a chamber. The unidirectional ratchet collar member is disposed on the hinge pin shaft for unidirectional axial movement and radial expansion induced by the simultaneous axial and rotational movement of the fin member that retains the fin member in the deployed position. |
| FILED | Friday, April 07, 2023 |
| APPL NO | 18/297171 |
| ART UNIT | RD00 — Amusement and Education Devices |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078459 | Vasudevan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Orbital Research Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Srikanth Vasudevan (Monroe, Connecticut); Paul Suchy (Parma, Ohio); Matthew C. Birch (Madison, Alabama) |
| ABSTRACT | Methods involve using a guided munition (e.g., a mortar round or a grenade) that utilizes deployable flow effectors, activatable flow effectors and/or active flow control devices to extend the range and enhance the precision of traditional unguided munitions without increasing the charge needed for launch. Sensors such as accelerometers, magnetometers, IR sensors, rate gyros, and motor controller sensors feed signals into a controller which then actuates or deploys the flow effectors/flow control devices to achieve the enhanced characteristics. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 17/984292 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Weapon Sights; Aiming F41G 7/222 (20130101) F41G 7/2253 (20130101) F41G 7/2293 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/14 (20130101) F42B 10/42 (20130101) F42B 10/44 (20130101) F42B 10/62 (20130101) F42B 15/01 (20130101) Original (OR) Class F42B 30/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078602 | Rose, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Paul B. Rose, Jr. (Oak Ridge, Tennessee); Jeremy Childress (Corvallis, Oregon) |
| ABSTRACT | A self-contained emitter assembly according to one embodiment is provided to generate and emit X-rays underwater for facilitating X-ray imaging. The self-contained emitter assembly may be operable by a user underwater without connection to an external power supply and/or control circuitry. |
| FILED | Monday, October 16, 2023 |
| APPL NO | 18/380464 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) Original (OR) Class G01N 23/083 (20130101) X-ray Technique H05G 1/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078654 | Brueck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven R. J. Brueck (Albuquerque, New Mexico); Daniel Feezell (Albuquerque, New Mexico); John Randall (Albuquerque, New Mexico); Tito Busani (Albuquerque, New Mexico); Joshua B. Ballard (Albuquerque, New Mexico); Mahmoud Behzadirad (Albuquerque, New Mexico); Ashwin Krishnan Rishinaramangalam (Albuquerque, New Mexico) |
| ABSTRACT | Provided is a composite metal-wide-bandgap semiconductor tip for scanning tunneling microscopy and/or scanning tunneling lithography, a method of forming, and a method for using the composite metal-wide-bandgap semiconductor tip. |
| FILED | Thursday, April 22, 2021 |
| APPL NO | 17/237697 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0004 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/16 (20130101) Original (OR) Class G01Q 70/06 (20130101) G01Q 70/10 (20130101) G01Q 70/12 (20130101) G01Q 70/14 (20130101) G01Q 80/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078720 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Anant Gupta (Madison, Wisconsin); Atul Ingle (Madison, Wisconsin); Andreas Velten (Madison, Wisconsin); Mohit Gupta (Madison, Wisconsin) |
| ABSTRACT | In accordance with some embodiments, systems, methods and media for single photon depth imaging with improved precision in ambient light conditions are provided. In some embodiments, the system comprises: a light source; a single photon detector; an attenuation element configured to provide a variable intensity attenuation factor; and a processor programmed to: (a)-determine an ambient light intensity associated with a scene point; (b)-select an attenuation factor based on the ambient light intensity; (c)-estimate a depth of the scene point based on a multiplicity of photon arrival times determined using the detector during a period of time during which light incident on the detector is attenuated by the selected attenuation factor and during which the light source is configured to periodically emit a pulse of light toward the scene point; (d)-repeat (a)-(c) for each of a multiplicity of scene points. |
| FILED | Friday, March 08, 2019 |
| APPL NO | 16/297320 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) G01S 7/4868 (20130101) G01S 17/10 (20130101) Original (OR) Class G01S 17/89 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078775 | Shapiro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sofar Ocean Technologies, Inc. (San Francisco, California) |
| ASSIGNEE(S) | Sofar Ocean Technologies, Inc. (San Francisco, California) |
| INVENTOR(S) | Evan Shapiro (San Francisco, California); Tim Janssen (Montara, California); Pieter Smit (Stanford, California) |
| ABSTRACT | A computer-implemented method for forecasting weather uses a trained machine learning model to determine the error in a weather forecast, e.g., for a selected ocean region. The machine learning model is configured to determine the predicted forecasting error given the weather forecast and a set of existing conditions. The weather forecast is adjusted using the predicted forecasting error to produce an augmented weather forecast. Training the machine learning model may include the utilization of hindcasting methods. Determination of existing conditions and other modeling may include the use of data from an array of metocean sensor nodes dispersed on a body of water. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 17/279477 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Meteorology G01W 1/00 (20130101) G01W 1/10 (20130101) Original (OR) Class G01W 1/18 (20130101) G01W 2001/006 (20130101) G01W 2203/00 (20130101) Electric Digital Data Processing G06F 11/00 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) G06N 3/08 (20130101) G06N 3/044 (20230101) G06N 3/045 (20230101) G06N 3/088 (20130101) G06N 20/00 (20190101) Technologies for Adaptation to Climate Change Y02A 90/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079102 | Gu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ronghui Gu (New York, New York); Jason Nieh (New York, New York); Runzhou Tao (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Ronghui Gu (New York, New York); Jason Nieh (New York, New York); Runzhou Tao (New York, New York) |
| ABSTRACT | Mechanisms for proving the correctness of software on relaxed memory hardware are provided, the mechanisms comprising: receiving a specification, a hardware model, and an implementation for the software to be executed on the relaxed memory hardware; evaluating the software using a sequentially consistent hardware model; evaluating the software using a relaxed memory hardware model and at least one of the following conditions: a data-race-free (DRF)-kernel condition; a no-barrier-misuse condition; a memory-isolation condition; a transactional-page-table condition; a write-once-kernel-mapping condition; and a weak-memory-isolation condition; and outputting an indication of whether the software is correct based on the evaluating the software using the sequentially consistent hardware model and the evaluating the software using the relaxed memory hardware model. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/376120 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3604 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079127 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CoreSecure Technologies, LLC (Princeton, New Jersey) |
| ASSIGNEE(S) | Coresecure Technologies, LLC (Princeton, New Jersey) |
| INVENTOR(S) | Ruby B. Lee (Princeton, New Jersey); Fangfei Liu (Hillsboro, Oregon) |
| ABSTRACT | Systems and methods for random fill caching and prefetching for secure cache memories are provided. The system dynamically de-correlates fetching a cache line to the processor from filling the cache with this cache line, due to a demand memory access, in order to provide greater security from information leakage due to cache side-channel attacks on cache memories. The system includes a random fill engine which includes a random number generator and an adjustable random fill window. Also provided is an adaptive random fill caching system which dynamically adapts the random fill window to a wide variety of computational workloads. Systems and methods for cache prefetching to improve system performance using adaptive random fill prefetching and random fill prefetching are also provided. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/208825 |
| ART UNIT | 2133 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/14 (20130101) G06F 12/0802 (20130101) G06F 12/0862 (20130101) Original (OR) Class G06F 12/0868 (20130101) G06F 2212/602 (20130101) G06F 2212/1052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079607 | Alhanahnah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Mohannad Alhanahnah (Madison, Wisconsin); Vaibhav Rastogi (Santa Clara, California); Somesh Jha (Madison, Wisconsin); Thomas Reps (Madison, Wisconsin) |
| ABSTRACT | A computerized technique for program simplification and specialization combines a partial interpretation of the program based on a subset of program functions to obtain variable states with concrete values at a program “neck.” These concrete values are then propagated as part of an optimization transformation that simplifies the program based on these constant values, for example, by eliminating branches that are never taken based on the constant values. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738158 |
| ART UNIT | 2191 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/443 (20130101) G06F 8/452 (20130101) G06F 8/4443 (20130101) Original (OR) Class G06F 9/445 (20130101) G06F 9/45504 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079671 | Blais et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | RAYTHEON BBN TECHNOLOGIES CORP. (Cambridge, Massachusetts) |
| INVENTOR(S) | Stéphane Yannick Blais (Framingham, Massachusetts); Michael Hassan Atighetchi (Framingham, Massachusetts); Samuel Cunningham Nelson (Sudbury, Massachusetts); Christopher Lawrence Willig (Chelmsford, Massachusetts) |
| ABSTRACT | Techniques are described herein for a messaging system to allow publishers that are aware of the identities of their respective subscribers to target content at those subscribers directly. This may be accomplished by allowing users and other targets (e.g., groups) to register their identities at particular computing nodes of a system. Then publishers (e.g., applications) may send out messages targeted at particular identities, and a publishing system may forward messages to appropriate nodes based on which identities are registered at those nodes. Legacy applications that are not able to target particular identities may instead connect to application adapters that are configured to learn which identities should be targeted by each application. In addition, anonymized identities may be used for application messages that need to cross between domains having differing security levels. |
| FILED | Friday, August 26, 2022 |
| APPL NO | 17/822628 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/546 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079922 | Youngblood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | XEROX CORPORATION (Norwalk, Connecticut) |
| ASSIGNEE(S) | XEROX CORPORATION (Norwalk, Connecticut) |
| INVENTOR(S) | Gregory M. Youngblood (Minden, Nevada); Matthew Shreve (Mountain View, California); Mark J. Stefik (Portola Valley, California); Robert Thomas Krivacic (San Jose, California); Lester D. Nelson (Santa Clara, California); Jacob Le (Palo Alto, California) |
| ABSTRACT | A system and method for translating a 2D image to a 3D image is provided. A 2D image having pixels grouped into tiles is obtained. Contour lines associated with an altitude value are located on the 2D image. The altitude values are determined. Each tile in the 2D image is represented using at least one voxel. A height map of the voxels is generated based on the contour lines and altitude values as a base layer for a 3D image. A terrain type of each of the voxels of the 3D image is determined and objects are placed in the 3D image. The 3D image is output. |
| FILED | Monday, January 09, 2023 |
| APPL NO | 18/152068 |
| ART UNIT | 2614 — Interprocess Communication and Software Development |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 15/04 (20130101) G06T 15/10 (20130101) Original (OR) Class G06T 15/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080114 | Bharadwaj et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
| INVENTOR(S) | Raj Mohan Bharadwaj (Maple Grove, Minnesota); Kyusung Kim (Plymouth, Minnesota); Kwong Wing Au (Bloomington, Minnesota); Paul Frederick Dietrich (Brooklyn Park, Minnesota); Piyush Ranade (Minneapolis, Minnesota); Andrew Peter Vechart (Plymouth, Minnesota); Megan Hawley (Roseville, Minnesota); Abraham Reddy (Minneapolis, Minnesota); Craig Schimmel (Rio Rancho, New Mexico); David Daniel Lilly (Ramona, California) |
| ABSTRACT | A method in an aircraft of using prognostic indicators for aircraft maintenance includes retrieving aircraft health data for a plurality of aircraft components wherein the aircraft health data includes at least one of mechanical systems condition indicator (CI) data, vibration spectrum data, resampled time-domain (RTD) data, and RTD spectrum data. The method includes estimating component health status information for the plurality of aircraft components using a plurality of prognostic modules wherein each prognostic module is configured to generate health status information for at least one of the aircraft components, the health status information includes at least one of a current health indicator and a prognostic indicator. The method also includes storing the component health status information for the aircraft components in a database onboard the aircraft, and causing the display of the health status information for the specific component on an aircraft display. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/155364 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/60 (20170101) Electric Digital Data Processing G06F 16/22 (20190101) G06F 16/955 (20190101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/0816 (20130101) Original (OR) Class G07C 5/0841 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080505 | Bond, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EngeniusMicro, LLC (Atlanta, Georgia) |
| ASSIGNEE(S) | EngeniusMicro, LLC (Atlanta, Georgia) |
| INVENTOR(S) | Arthur Gernt Bond, III (Auburn, Alabama); Benoit Hamelin (Atlanta, Georgia) |
| ABSTRACT | The present disclosure can relate to a thermionic emission device. The thermionic emission device can include a substrate layer, an insulating layer deposited onto an uppermost surface of the substrate layer, and an electron emitting layer deposited onto an uppermost surface of the insulating layer. The electron emitting layer, the insulating layer, and the substrate layer each can include a first etching and a second etching oriented according to a photoresist pattern applied to an uppermost surface of the electron emitting layer. The first etching and the second etching can converge to form a cavity in the substrate layer beneath a beam suspended above the cavity. The beam can comprise an unetched region of the electron emitting layer and the insulating layer oriented between the first etching and the second etching. |
| FILED | Thursday, January 04, 2024 |
| APPL NO | 18/404139 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 1/14 (20130101) H01J 1/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080506 | Mohammadi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Saeed Mohammadi (Zionsville, Indiana); Shabnam Ghotbi (Lafayette, Indiana) |
| ABSTRACT | A field emitter array (FEA) vacuum transistor is disclosed which includes a substrate and a plurality of nanorods formed of a first polarity dopant on the substrate. |
| FILED | Tuesday, September 05, 2023 |
| APPL NO | 18/242185 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 21/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080783 | Eom et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Chang-Beom Eom (Madison, Wisconsin); Tianxiang Nan (Ithaca, New York); Jonathon Schad (Madison, Wisconsin) |
| ABSTRACT | Voltage-controlled spin field effect transistors (“spin transistors”) and methods for their use in switching applications are provided. In the spin transistors, spin current is transported from a spin injection contact to a spin detection contact through a multiferroic antiferromagnetic channel via magnon propagation. The spin current transport is modulated by the application of a gate voltage that increases the number of domain boundaries the multiferroic antiferromagnetic material. |
| FILED | Thursday, March 05, 2020 |
| APPL NO | 16/809970 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/66984 (20130101) Original (OR) Class Electric solid-state devices not otherwise provided for H10N 50/20 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080823 | Razeghi |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Manijeh Razeghi (Wilmette, Illinois) |
| ABSTRACT | Diffusion-based and ion implantation-based methods are provided for fabricating planar photodetectors. The methods may be used to fabricate planar photodetectors comprising type II superlattice absorber layers but without mesa structures. The fabricated planar photodetectors exhibit high quantum efficiencies, low dark current densities, and high specific detectivities as compared to photodetectors having mesa structures. |
| FILED | Friday, March 17, 2023 |
| APPL NO | 18/185507 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/101 (20130101) H01L 31/105 (20130101) H01L 31/1035 (20130101) H01L 31/1844 (20130101) Original (OR) Class H01L 31/03046 (20130101) H01L 31/035236 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080946 | Chisum et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Jonathan Chisum (South Bend, Indiana); Nicolas Garcia (South Bend, Indiana) |
| ABSTRACT | An electromagnetic antenna includes a channel configured to serve as a waveguide for electromagnetic radiation, a first and second feed disposed next to each other inside the channel at a first end thereof, the first and second feed being configured to radiate electromagnetic waves into the channel, an aperture lens disposed inside the channel near a second end thereof opposite to the first end, the aperture lens being configured to output collimated beams, a first focal lens disposed inside the channel adjacent to an outlet of the first feed, the first focal lens being configured to squint a beam radiated from the first feed toward a center of the aperture lens, and a second focal lens disposed inside the channel adjacent to an outlet of the second feed, the second focal lens being configured to squint a beam radiated from the second feed toward the center of the aperture lens. |
| FILED | Friday, April 15, 2022 |
| APPL NO | 17/721898 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 19/062 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080984 | Helle |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Michael H. Helle (Arlington, Virginia) |
| ABSTRACT | A laser architecture for selectively producing short high-energy laser pulses having octave-spanning, continuous tunability. Two oppositely chirped pulses are used in combination with a pair of tunable pulse stretcher/compressors to produce a short, high-energy, tunable, broadband pulse. |
| FILED | Thursday, August 26, 2021 |
| APPL NO | 17/412339 |
| ART UNIT | 2634 — Digital Communications |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/1819 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/39 (20130101) G02F 1/392 (20210101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0057 (20130101) Original (OR) Class H01S 3/0085 (20130101) H01S 3/1106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080988 | Schibli |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Thomas Richard Schibli (Boulder, Colorado) |
| ABSTRACT | A photonic-based microwave generator includes a mode-locked laser that generates an optical pulse train, a feedback photodiode that samples the optical pulse train, and a servo amplifier that processes the photodiode output into a servo signal. The servo signal controls the mode-locked laser to suppress relative intensity noise on the optical pulse train. The microwave generator may also include a microwave photodiode for converting the optical pulse train into a microwave signal. The microwave generator may also include a second servo amplifier that processes a low-frequency output of the microwave photodiode into a second servo signal that drives an optical modulator that modulates the optical pulse train. The microwave photodiode, optical modulator, and servo amplifier form a feedback loop that suppresses amplitude noise on the microwave signal. By reducing amplitude noise and relative intensity noise, phase noise caused by amplitude-to-phase noise conversion is minimized. |
| FILED | Tuesday, February 23, 2021 |
| APPL NO | 17/182527 |
| ART UNIT | 2849 — Digital Communications |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0078 (20130101) H01S 3/0085 (20130101) H01S 3/107 (20130101) H01S 3/1118 (20130101) H01S 3/1304 (20130101) H01S 3/1305 (20130101) H01S 3/1306 (20130101) H01S 3/1307 (20130101) Original (OR) Class H01S 3/1312 (20130101) H01S 3/10046 (20130101) H01S 2301/02 (20130101) Transmission H04B 2210/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12081180 | Garay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Edgar Felipe Garay (Atlanta, Georgia); Hua Wang (Atlanta, Georgia) |
| ABSTRACT | A dual-drive power amplifier (PA) where the PA core includes a differential pair of transistors M1 and M2 that are driven by a coupling network having two transmission-line couplers, where a first transmission line section of a coupler is configured to transmit an input signal Vin through to drive a gate of the opposite transistor, while the second transmission line section is grounded at one end and coupled with the first transmission line section such that a coupled portion αVin of the input signal Vin drives the source terminal of a corresponding transistor. The arrangement of the coupling network allows the source terminals to be driven below ground potential. Embodiments disclosed here further provide an input matching network, a driver, an inter-stage matching network, and an output network for practical implementation of the PA core. |
| FILED | Monday, October 10, 2022 |
| APPL NO | 18/045239 |
| ART UNIT | 2843 — Electrical Circuits and Systems |
| CURRENT CPC | Amplifiers H03F 1/32 (20130101) H03F 1/0205 (20130101) H03F 1/565 (20130101) H03F 3/245 (20130101) Original (OR) Class H03F 2200/222 (20130101) H03F 2200/387 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12081411 | Morcom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher J Morcom (Newport, Rhode Island); Nathaniel C Couch (Portsmouth, Rhode Island) |
| ABSTRACT | A method for network infrastructure assessment is provided. An assessor tool portion is replicated on a network origination node. A plurality of authentication keys associated with a root authentication key are generated. Network nodes are recursively enumerated by the assessor tool. In the recursion, information on the parent node is enumerated and reported to a controller of the network; the parent node is marked as enumerated; child nodes connected to the parent node are detected; at least a portion of the assessor tool is replicated on a child node that is not enumerated but has a valid assigned authentication key; and recursion is continued with the child node as the parent node. The reported information is processed to produce a network infrastructure assessment. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/123390 |
| ART UNIT | 2447 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/088 (20130101) H04L 41/145 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12081450 | Cocker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | XEROX CORPORATION (Norwalk, Connecticut) |
| INVENTOR(S) | Eric D. Cocker (Redwood City, California); Matthew A. Shreve (Campbell, California); Francisco E. Torres (San Jose, California) |
| ABSTRACT | A system and method provide a combination of a modular message structure, a priority-based message packing scheme, and a data packet queue management system to optimize the information content of a transmitted message in, for example, the Ocean of Things (OoT) environment. The modular message structure starts with a header that provides critical information and reference points for time and location. The rest of the message is composed of modular data packets, each of which has a data ID section that the message decoder uses for reference when reconstructing the message contents, an optional size section that specifies the length of the following data section if it can contain data of variable length, and a data section that can be compressed in a manner unique to that data type. The message packing scheme uses a combination of priority level and minimum reporting interval, both of which are dynamically configurable for each data packet type, to maximize the value of the information contained in the modular data packets included in each message. Finally, the data packet queues manage temporary storage of data packets that have been generated but not yet included in an outgoing message. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/898985 |
| ART UNIT | 2478 — Multiplex and VoIP |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/022 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/06 (20130101) H04L 47/564 (20130101) H04L 47/6275 (20130101) Original (OR) Class H04L 69/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12081573 | Kaplan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Peraton Labs Inc. (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | Peraton Labs Inc. (Basking Ridge, New Jersey) |
| INVENTOR(S) | Michael Kaplan (Basking Ridge, New Jersey); David Shur (Basking Ridge, New Jersey); Vikram Kaul (Basking Ridge, New Jersey); Thomas Bowen (Basking Ridge, New Jersey) |
| ABSTRACT | There is set forth herein obtaining data traffic monitoring data, the data traffic monitoring data being in dependence on monitoring of traffic received by a container of a protected computing environment; obtaining data traffic monitoring data, the data traffic monitoring data being in dependence on monitoring of traffic received by a processing resource of a computing environment; obtaining a state of the processing resource and provisioning a utility processing resource to include the state of the processing resource; and configuring the computing environment to route data traffic to the utility processing resource. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 18/055209 |
| ART UNIT | 2492 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/08 (20130101) H04L 41/082 (20130101) H04L 41/0806 (20130101) H04L 43/08 (20130101) H04L 43/16 (20130101) H04L 43/062 (20130101) H04L 43/0876 (20130101) H04L 45/00 (20130101) H04L 47/00 (20130101) H04L 63/10 (20130101) H04L 63/1425 (20130101) Original (OR) Class H04L 63/1491 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12081592 | Halford |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Caliola Engineering, LLC (Colorado Springs, Colorado) |
| ASSIGNEE(S) | Caliola Engineering, LLC (Colorado Springs, Colorado) |
| INVENTOR(S) | Thomas R. Halford (Colorado Springs, Colorado) |
| ABSTRACT | A system and method for cryptographically securing data communications between a group of networked devices establishes and maintains an overlay network at the Application Layer, on top of a unicast routing service provided at the Internetworking Layer. The overlay network provides first, the routes that are used to deliver multicast datagrams and second, the cryptographic keys used to secure multicast datagrams. A common cryptographic key is established between all members of each group, and end-to-end encryption ensures that multicast datagrams can be accessed only by authorized group members. In other embodiments, keys are established between pairs of adjacent devices in the overlay network, and hop-by-hop encryption ensures that multicast datagrams can be accessed only by overlay network members. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/305930 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0841 (20130101) H04L 63/065 (20130101) H04L 63/168 (20130101) Original (OR) Class H04L 63/0435 (20130101) H04L 63/0464 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12082374 | Graham |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Simmonds Precision Products, Inc. (Vergennes, Vermont) |
| ASSIGNEE(S) | Simmonds Precision Products, Inc. (Vergennes, Vermont) |
| INVENTOR(S) | Jason Graham (Prior Lake, Minnesota) |
| ABSTRACT | A heatsink can include a body, one or more thermal fin arrays defined by and/or extending from the body, and a phase change material disposed in contact with the one or more fin arrays. The phase change material can be configured to be a first phase in a cool state and a second phase in a heated state. The phase change material is configured to be cooled back to the solid state. |
| FILED | Friday, October 08, 2021 |
| APPL NO | 17/497671 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/0203 (20130101) H05K 7/2039 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12076117 | Bolus |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Huxley Medical, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Huxley Medical, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Nicholas Bradford Bolus (Birmingham, Alabama) |
| ABSTRACT | The present disclosure relates to a cardiorespiratory analysis system that includes, in at least one embodiment, a conformal patch with a compressible viscoelastic interface and an array of sensors, including, but not limited to a photoplethysmography (PPG) sensor, a 3-axis accelerometer, and an electrocardiogram (ECG) sensor. In at least one embodiment, the system includes a microcontroller wired to the array of sensors. According to at least one embodiment, the system uses computing techniques to derive features from the array of sensors and determines one or cardiorespiratory characteristics of a patient based on the derived features. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/299539 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/02 (20130101) Original (OR) Class A61B 5/318 (20210101) A61B 5/1455 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076150 | Trayanova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Natalia A. Trayanova (Baltimore, Maryland); Henry R. Halperin (Baltimore, Maryland); Hermenegild Arevalo (Baltimore, Maryland); Jason Constantino (Baltimore, Maryland) |
| ABSTRACT | A method of planning a patient-specific cardiac procedure according to an embodiment of the current invention includes receiving three-dimensional imaging data of a patient's heart, simulating at least one of electrophysiological or electromechanical activity of at least a portion of the patient's heart using the three-dimensional imaging data, and planning the patient-specific cardiac procedure based on the simulating. The cardiac procedure is for providing a preselected alteration of at least one of electrophysiological or electromechanical behavior of the patient's heart. |
| FILED | Monday, August 17, 2020 |
| APPL NO | 16/995513 |
| ART UNIT | 1671 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/283 (20210101) Original (OR) Class A61B 5/319 (20210101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/466 (20130101) A61B 6/503 (20130101) A61B 6/5223 (20130101) A61B 8/13 (20130101) A61B 8/0883 (20130101) A61B 34/10 (20160201) A61B 2505/05 (20130101) A61B 2576/023 (20130101) Image Data Processing or Generation, in General G06T 19/00 (20130101) G06T 2210/41 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076366 | Soliman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| ASSIGNEE(S) | Extend Biosciences, Inc. (Newton, Massachusetts) |
| INVENTOR(S) | Tarik Soliman (Cambridge, Massachusetts); Laura M. Hales (Cambridge, Massachusetts); Daniel B. Hall (Easton, Massachusetts); Christopher So (Henderson, Nevada); Howard P. Sard (Arlington, Massachusetts); Vishnumurthy Hegde (Chelmsford, Massachusetts) |
| ABSTRACT | The invention provides non-hormonal vitamin D conjugated to apelin proteins that result in increased absorption, bioavailability or circulating half-life when compared to non-conjugated forms. In some embodiments, the vitamin D targeting groups are coupled to the apelin proteins via the third carbon on the vitamin D backbone. |
| FILED | Friday, July 03, 2020 |
| APPL NO | 16/920652 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/10 (20130101) Original (OR) Class A61K 38/22 (20130101) A61K 47/60 (20170801) A61K 47/551 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076409 | Camacho et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Kathryn M. Camacho (Los Angeles, California); Stefano Menegatti (Raleigh, North Carolina); Sunny Kumar (Aliso Viejo, California); Douglas Vogus (Goleta, California); Samir Mitragotri (Lexington, Massachusetts) |
| ABSTRACT | Pharmaceutical compositions comprising two or more therapeutically active agents, such as two or more anticancer agents, conjugated to one or more biocompatible polymers, wherein the molar ratio of the agents and/or schedules of delivery provide a synergistic therapeutic effect, are described. Methods of making and using the pharmaceutical compositions are further described. In one embodiment, the pharmaceutical compositions contain topoisomerase I and topoisomerase II inhibitors conjugated to the same or different biocompatible polymers. The two or more anticancer agents are covalently coupled to the polymer(s), and thereby can be delivered to a tumor at a molar ratio which provides a synergistic effect. Optionally, the agents are coupled indirectly to the polymer(s) via a linker. |
| FILED | Thursday, December 09, 2021 |
| APPL NO | 17/546480 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 47/61 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076440 | Dave et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| ASSIGNEE(S) | New Jersey Institute of Technology (Newark, New Jersey) |
| INVENTOR(S) | Rajesh N. Dave (Princeton, New Jersey); Sangah Kim (Newark, New Jersey); Zhixing Lin (Newark, New Jersey) |
| ABSTRACT | High (greater than 30%) and/or low (less than 10%) loaded multiple API powdered/nanoparticle were tabulated with increased flowability and physical properties. Properties include blend flowability and uniformity, bulk packing density, compactability, tensile strength, and dissolution. Blending is done through solventless dry mechanical coating of at least one minority API component defined as the API component with the least weight per volume surface coated with nano-sized powders in lesser amounts by wt % of the blend, and preferably less than 10% dry coated of the minority API. An excipient may be dry coated in the lesser amount wherein the excipient is a minority component. Both minority excipient and minority API may be dry coated. Using dry coating instead of dry granulation and/or wet granulation techniques in producing tablets saves manufacturing steps, costs, and produces higher quality tablets with surprisingly higher properties than expected for low flowability solid powdered ingredients. |
| FILED | Wednesday, July 12, 2023 |
| APPL NO | 18/221143 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/143 (20130101) Original (OR) Class A61K 9/1682 (20130101) A61K 31/192 (20130101) A61K 45/06 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076444 | Giridhar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Arun V. Giridhar (West Lafayette, Indiana); Michael Harris (West Lafayette, Indiana); Gintaras V. Reklaitis (West Lafaytte, Indiana); Lynne S. Taylor (West Lafaytte, Indiana); Zoltan K. Nagy (West Lafayette, Indiana); Elcin Icten (West Lafayette, Indiana); Frederick Fiesser (Philadelphia, Pennsylvania); Laura Hirshfield (Ann Arbor, Michigan) |
| ABSTRACT | Systems and methods for delivering active ingredients, such as pharmaceutically active ingredients, to substrates are described herein. The active ingredients are delivered as fluids to a fluid-dispensing device for the creation of one or more drops for deposition onto substrates such as for the creation of microdoses. The invention further includes microdoses made by such processes. |
| FILED | Tuesday, January 10, 2023 |
| APPL NO | 18/152394 |
| ART UNIT | 1717 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/7007 (20130101) Original (OR) Class A61K 31/167 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) A61K 31/415 (20130101) A61K 31/635 (20130101) A61K 47/10 (20130101) A61K 47/14 (20130101) A61K 47/34 (20130101) A61K 47/38 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 4/002 (20130101) B01J 4/02 (20130101) B01J 4/008 (20130101) B01J 2204/005 (20130101) B01J 2204/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076590 | Konofagou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| INVENTOR(S) | Elisa E. Konofagou (New York, New York); Fabrice Marquet (New York, New York); Yao-Sheng Tung (New York, New York) |
| ABSTRACT | Systems and methods for cavitation-guided opening of a targeted region of tissue within a primate skull are provided. In one example, a method includes delivering one or more microbubbles to proximate the targeted region, applying an ultrasound beam, using a transducer, through the skull of the primate to the targeted region to open the tissue, transcranially acquiring acoustic emissions produced from an interaction between the one or more microbubbles and the tissue, and determining a cavitation spectrum from the acquired acoustic emissions. |
| FILED | Wednesday, March 09, 2022 |
| APPL NO | 17/690523 |
| ART UNIT | 3798 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/481 (20130101) A61B 8/0808 (20130101) A61B 17/2258 (20130101) A61B 90/10 (20160201) A61B 2017/00106 (20130101) A61B 2017/22008 (20130101) A61B 2017/22089 (20130101) A61B 2090/378 (20160201) A61B 2503/40 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) Original (OR) Class A61N 2007/0039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076748 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Panama) |
| INVENTOR(S) | Xianming Dai (University Park, Pennsylvania); Birgitt M. Boschitsch (University Park, Pennsylvania); Jing Wang (University Park, Pennsylvania); Tak-Sing Wong (University Park, Pennsylvania); Nan Sun (University Park, Pennsylvania) |
| ABSTRACT | Substrates having a textured surface that can maintain or improve droplet mobility in both the Cassie and Wenzel states include a textured surface and a conformal lubricant layer thereover. The textured surface can include a plurality of raised first elements and a plurality of second elements thereon and the conformal lubricant layer over the plurality of raised first elements and covering the plurality of second elements. The plurality of raised first elements can have an average height of between 0.5 μm and 500 μm, and the plurality of second elements can have an average height of between 0.01 μm and 10 μm. Such substrates can be prepared by texturing a surface of a substrate with a plurality of raised first elements and a plurality of second elements thereon; optionally silanizing the textured surface and applying a lubricant layer over the plurality of raised first elements and between the plurality of second elements. |
| FILED | Tuesday, August 27, 2019 |
| APPL NO | 16/551895 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/00 (20130101) B05D 3/101 (20130101) B05D 5/02 (20130101) B05D 5/08 (20130101) Original (OR) Class Cleaning in General; Prevention of Fouling in General B08B 17/065 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 59/022 (20130101) B29C 2059/023 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0092 (20130101) B29K 2995/0093 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12076966 | Anthamatten et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | The University of Rochester (Rochester, New York) |
| INVENTOR(S) | Mitchell Anthamatten (Rochester, New York); Alexander A. Shestopalov (Rochester, New York) |
| ABSTRACT | Describes are methods of contacting printing with a shape-memory stamp. For example, disclosed herein are methods of patterning thin films using shape memory contact printing. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/678222 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/025 (20130101) Original (OR) Class B32B 37/0046 (20130101) B32B 2457/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077478 | Randall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Clive A. Randall (University Park, Pennsylvania); Jing Guo (University Park, Pennsylvania); Amanda Baker (University Park, Pennsylvania); Michael Lanagan (University Park, Pennsylvania); Hanzheng Guo (University Park, Pennsylvania) |
| ABSTRACT | Cold sintering of materials includes using a process of combining at least one inorganic compound, e.g., ceramic, in particle form with a solvent that can partially solubilize the inorganic compound to form a mixture; and applying pressure and a low temperature to the mixture to evaporate the solvent and densify the at least one inorganic compound to form sintered materials. |
| FILED | Friday, April 09, 2021 |
| APPL NO | 17/226653 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/16 (20130101) B32B 7/04 (20130101) B32B 9/005 (20130101) B32B 9/045 (20130101) B32B 9/048 (20130101) B32B 15/08 (20130101) B32B 15/16 (20130101) B32B 18/00 (20130101) B32B 27/08 (20130101) B32B 27/14 (20130101) B32B 27/32 (20130101) B32B 27/34 (20130101) B32B 27/40 (20130101) B32B 27/281 (20130101) B32B 27/285 (20130101) B32B 27/286 (20130101) B32B 27/288 (20130101) B32B 27/302 (20130101) B32B 27/304 (20130101) B32B 27/308 (20130101) B32B 27/322 (20130101) B32B 27/365 (20130101) B32B 2250/02 (20130101) B32B 2262/101 (20130101) B32B 2262/106 (20130101) B32B 2264/107 (20130101) B32B 2307/20 (20130101) B32B 2307/50 (20130101) B32B 2307/202 (20130101) B32B 2307/204 (20130101) B32B 2307/546 (20130101) B32B 2307/702 (20130101) B32B 2307/704 (20130101) B32B 2307/728 (20130101) B32B 2307/732 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/447 (20130101) C04B 35/453 (20130101) C04B 35/486 (20130101) C04B 35/495 (20130101) C04B 35/634 (20130101) C04B 35/638 (20130101) C04B 35/645 (20130101) Original (OR) Class C04B 35/4682 (20130101) C04B 35/5152 (20130101) C04B 35/6263 (20130101) C04B 35/6264 (20130101) C04B 35/62222 (20130101) C04B 35/62685 (20130101) C04B 2235/77 (20130101) C04B 2235/604 (20130101) C04B 2235/656 (20130101) C04B 2235/785 (20130101) C04B 2235/3201 (20130101) C04B 2235/3203 (20130101) C04B 2235/3224 (20130101) C04B 2235/3236 (20130101) C04B 2235/3239 (20130101) C04B 2235/3256 (20130101) C04B 2235/3258 (20130101) C04B 2235/3272 (20130101) C04B 2235/3284 (20130101) C04B 2235/3291 (20130101) C04B 2235/3298 (20130101) C04B 2235/5436 (20130101) C04B 2235/6026 (20130101) C04B 2235/6562 (20130101) C04B 2235/6567 (20130101) C04B 2235/6588 (20130101) C04B 2237/068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077626 | Veige et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Adam S. Veige (Gainesville, Florida); Christopher D. Roland (Danville, California) |
| ABSTRACT | Provided herein are complexes for polymerization of linear alkynes to cyclic poly(alkynes), and methods of making and using same. For example, provided herein are compounds of formula (I) or formula (IV): |
| FILED | Tuesday, March 03, 2020 |
| APPL NO | 17/436420 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 4/78 (20130101) Original (OR) Class C08F 8/04 (20130101) C08F 38/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077638 | Oakey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Wyoming (Laramie, Wyoming) |
| ASSIGNEE(S) | University of Wyoming (Laramie, Wyoming) |
| INVENTOR(S) | John Oakey (Laramie, Wyoming); Kaspars Krutkramelis (Laramie, Wyoming); Bingzhao Xia (Calamvale, Australia) |
| ABSTRACT | Provided herein are methods utilizing microfluidics for the oxygen-controlled generation of microparticles and hydrogels having controlled microparticle sizes and size distributions and products from provided methods. The included methods provide the generation of microparticles by polymerizing an aqueous solution dispersed in a non-aqueous continuous phase in an oxygen-controlled environment. The process allows for control of size of the size of the aqueous droplets and, thus, control of the size of the generated microparticles which may be used in biological applications. |
| FILED | Wednesday, October 26, 2016 |
| APPL NO | 15/335184 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5026 (20130101) A61K 35/12 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) A61L 27/18 (20130101) A61L 27/38 (20130101) A61L 27/52 (20130101) A61L 27/56 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 23/41 (20220101) B01F 25/4331 (20220101) B01F 33/3011 (20220101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2/06 (20130101) B01J 13/0052 (20130101) B01J 19/0093 (20130101) B01J 2219/00792 (20130101) B01J 2219/00936 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/32 (20130101) C08F 2/48 (20130101) C08F 216/125 (20130101) C08F 222/102 (20200201) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) Original (OR) Class C08J 9/26 (20130101) C08J 2201/046 (20130101) C08J 2205/022 (20130101) C08J 2207/10 (20130101) C08J 2335/02 (20130101) C08J 2345/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077741 | Slater et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | John H. Slater (Landenberg, Pennsylvania); Shantanu Pradhan (Chennai, India); Cindy Jazmin Farino Reyes (Claymont, Delaware) |
| ASSIGNEE(S) | University Of Delaware (Newark, Delaware) |
| INVENTOR(S) | John H. Slater (Landenberg, Pennsylvania); Shantanu Pradhan (Chennai, India); Cindy Jazmin Farino Reyes (Claymont, Delaware) |
| ABSTRACT | The present invention discloses crosslinked poly(alkylene glycol) (PAG)-based hydrogel compositions, systems containing a plurality of cancer cells in contact with a cell culture media and encapsulated in the crosslinked PAG-based hydrogel composition and methods of making such crosslinked hydrogel compositions and systems. Also disclosed herein are methods of using such compositions and systems, such as, for example for screening an agent for effectiveness of the agent against cancer cells. Also disclosed herein are kits containing one or more components including one or more systems of the present disclosure and one or more instructions. |
| FILED | Thursday, June 04, 2020 |
| APPL NO | 16/893330 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Peptides C07K 5/1019 (20130101) C07K 5/1021 (20130101) C07K 7/06 (20130101) C07K 7/08 (20130101) Apparatus for Enzymology or Microbiology; C12M 25/00 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0693 (20130101) C12N 2503/00 (20130101) C12N 2533/40 (20130101) C12N 2533/50 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 21/6428 (20130101) G01N 33/5011 (20130101) G01N 33/5091 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077764 | Voytas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Daniel F. Voytas (Falcon Heights, Minnesota); Ryan A. Nasti (Berkeley, California); Michael F. Maher (St. Paul, Minnesota) |
| ABSTRACT | Materials and methods for inducing genetic alterations in meristematic plant tissue are provided herein. |
| FILED | Friday, March 03, 2023 |
| APPL NO | 18/178290 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 4/008 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8213 (20130101) C12N 15/8229 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) C12Q 2600/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077776 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ying Zhang (Shijiazhuang, China PRC); Julia Xiaojun Zhao (Grand Forks, North Dakota); Diane Darland (Grand Forks, North Dakota) |
| ASSIGNEE(S) | UNIVERSITY OF NORTH DAKOTA (Grand Forks, North Dakota) |
| INVENTOR(S) | Ying Zhang (Shijiazhuang, China PRC); Julia Xiaojun Zhao (Grand Forks, North Dakota); Diane Darland (Grand Forks, North Dakota) |
| ABSTRACT | A method of making a porous three-dimensional graphene mesh includes combining a graphene-containing material and a polymer having a plurality of hydroxyl groups in an alcohol solvent to form a mixture, adding a salt to the mixture, heating the mixture to form a gel, and washing the gel with water to remove the salt from the gel, leaving behind stable pores to form a scaffold. A three-dimensional porous graphene mesh includes a graphene-containing material and a polymer. The polymer is crosslinked with the graphene-containing material such that the Young's Modulus of the mesh is at least about 5 GPa. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/214195 |
| ART UNIT | 1699 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0068 (20130101) Original (OR) Class C12N 2533/40 (20130101) C12N 2537/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077811 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David Yu Zhang (Cambridge, Massachusetts); Peng Yin (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are primers and primer systems having improved specificity and kinetics over existing primers, and methods of use thereof. |
| FILED | Friday, February 05, 2021 |
| APPL NO | 17/169145 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6832 (20130101) C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6848 (20130101) C12Q 1/6853 (20130101) Original (OR) Class C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/161 (20130101) C12Q 2525/301 (20130101) C12Q 2525/301 (20130101) C12Q 2537/161 (20130101) C12Q 2537/161 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) C12Q 2537/1373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078587 | Diebold et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BECTON, DICKINSON AND COMPANY (Franklin Lakes, New Jersey) |
| ASSIGNEE(S) | BECTON, DICKINSON AND COMPANY (Franklin Lakes, New Jersey) |
| INVENTOR(S) | Eric D. Diebold (Menlo Park, California); Keegan Owsley (Campbell, California); Jonathan Lin (San Gabriel, California) |
| ABSTRACT | In one aspect, a method of sorting cells in a flow cytometry system is disclosed, which includes illuminating a cell with radiation having at least two optical frequencies shifted from one another by a radiofrequency to elicit fluorescent radiation from the cell, detecting the fluorescent radiation to generate temporal fluorescence data, and processing the temporal fluorescence data to arrive at a sorting decision regarding the cell without generating an image (i.e., a pixel-by-pixel image) of the cell based on the fluorescence data. In some cases, the sorting decision can be made with a latency less than about 100 microseconds. In some embodiments, the above method of sorting cells can have a sub-cellular resolution. In some embodiments, a single radiofrequency shift is employed to separate the optical frequencies while in other such embodiments a plurality of different radiofrequency shifts are employed. |
| FILED | Tuesday, September 27, 2022 |
| APPL NO | 17/953976 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/147 (20130101) G01N 15/149 (20240101) G01N 15/1429 (20130101) G01N 15/1434 (20130101) Original (OR) Class G01N 21/6402 (20130101) G01N 21/6428 (20130101) G01N 2015/1006 (20130101) G01N 2015/1447 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078595 | Wei |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Greensboro (Greensboro, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT GREENSBORO (Greensboro, North Carolina) |
| INVENTOR(S) | Jianjun Wei (Oak Ridge, North Carolina) |
| ABSTRACT | In one aspect, nanoplasmonic devices are described herein. In some embodiments, a nanoplasmonic device comprises a radiation transmissive substrate, a metal layer positioned on the substrate and at least one aperture extending through the metal layer to the radiation transmissive substrate, wherein width of the aperture decreases with increasing depth of the aperture. |
| FILED | Thursday, April 09, 2020 |
| APPL NO | 16/844707 |
| ART UNIT | 1678 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2300/0627 (20130101) B01L 2300/0887 (20130101) B01L 2300/0896 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/554 (20130101) Original (OR) Class G01N 21/6458 (20130101) G01N 33/57488 (20130101) G01N 2201/12 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078630 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PATH EX, Inc. (Houston, Texas) |
| ASSIGNEE(S) | PATH EX, INC. (Houston, Texas) |
| INVENTOR(S) | Sinead E. Miller (Houston, Texas); Jeffrey Ransden (Houston, Texas); Alan Bachman (Houston, Texas) |
| ABSTRACT | A device for the capture and adsorption of blood-borne materials of interest comprising a fluidic cartridge with at least one inlet and at least one outlet; a multidirectional fluidic channel between the at least one inlet and the at least one outlet; said multidirectional fluidic channel comprising at least one inner wall; and a substance coating at least a portion of the at least one inner wall of the multidirectional fluidic channel. |
| FILED | Tuesday, June 16, 2020 |
| APPL NO | 16/902745 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 2300/0854 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/492 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078654 | Brueck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven R. J. Brueck (Albuquerque, New Mexico); Daniel Feezell (Albuquerque, New Mexico); John Randall (Albuquerque, New Mexico); Tito Busani (Albuquerque, New Mexico); Joshua B. Ballard (Albuquerque, New Mexico); Mahmoud Behzadirad (Albuquerque, New Mexico); Ashwin Krishnan Rishinaramangalam (Albuquerque, New Mexico) |
| ABSTRACT | Provided is a composite metal-wide-bandgap semiconductor tip for scanning tunneling microscopy and/or scanning tunneling lithography, a method of forming, and a method for using the composite metal-wide-bandgap semiconductor tip. |
| FILED | Thursday, April 22, 2021 |
| APPL NO | 17/237697 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0004 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/16 (20130101) Original (OR) Class G01Q 70/06 (20130101) G01Q 70/10 (20130101) G01Q 70/12 (20130101) G01Q 70/14 (20130101) G01Q 80/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078802 | Hua et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Hong Hua (Tucson, Arizona); Hekun Huang (Tucson, Arizona) |
| ABSTRACT | Head-mounted light field display with integral imaging and relay group. |
| FILED | Tuesday, March 06, 2018 |
| APPL NO | 16/491836 |
| ART UNIT | 2628 — Selective Visual Display Systems |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 3/0056 (20130101) G02B 27/0075 (20130101) G02B 27/0172 (20130101) Original (OR) Class G02B 30/10 (20200101) G02B 2027/0127 (20130101) G02B 2027/0134 (20130101) G02B 2027/0145 (20130101) G02B 2027/0185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078834 | Rubin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Noah A. Rubin (Cambridge, Massachusetts); Federico Capasso (Cambridge, Massachusetts) |
| ABSTRACT | An optical component includes a substrate and a metasurface comprising one or more linearly birefringent elements. The linearly birefringent elements define a grating configured to implement parallel polarization analysis for a plurality of polarization orders for incident light of an arbitrary polarization. |
| FILED | Tuesday, April 14, 2020 |
| APPL NO | 17/603574 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 4/04 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) G02B 5/1833 (20130101) G02B 5/3083 (20130101) Original (OR) Class G02B 27/4261 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078911 | Wu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
| INVENTOR(S) | Hui Wu (Pittsford, New York) |
| ABSTRACT | Methods of manufacturing and operating a monolithically integrated optical phase array (OPA) chip device, and the device itself. A three-dimensional (3-D) integrated optical phase array (OPA) chip device. A system of complementary metal-oxide-semiconductor (CMOS) electronics integrated with a three-dimensional integrated optical array chip device. A method of three-dimension photonic integration to improve optical power in optical phase arrays. |
| FILED | Monday, October 05, 2020 |
| APPL NO | 17/754358 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4814 (20130101) G01S 7/4817 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/2955 (20130101) Original (OR) Class G02F 2202/105 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079102 | Gu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ronghui Gu (New York, New York); Jason Nieh (New York, New York); Runzhou Tao (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Ronghui Gu (New York, New York); Jason Nieh (New York, New York); Runzhou Tao (New York, New York) |
| ABSTRACT | Mechanisms for proving the correctness of software on relaxed memory hardware are provided, the mechanisms comprising: receiving a specification, a hardware model, and an implementation for the software to be executed on the relaxed memory hardware; evaluating the software using a sequentially consistent hardware model; evaluating the software using a relaxed memory hardware model and at least one of the following conditions: a data-race-free (DRF)-kernel condition; a no-barrier-misuse condition; a memory-isolation condition; a transactional-page-table condition; a write-once-kernel-mapping condition; and a weak-memory-isolation condition; and outputting an indication of whether the software is correct based on the evaluating the software using the sequentially consistent hardware model and the evaluating the software using the relaxed memory hardware model. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/376120 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 11/3604 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079127 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CoreSecure Technologies, LLC (Princeton, New Jersey) |
| ASSIGNEE(S) | Coresecure Technologies, LLC (Princeton, New Jersey) |
| INVENTOR(S) | Ruby B. Lee (Princeton, New Jersey); Fangfei Liu (Hillsboro, Oregon) |
| ABSTRACT | Systems and methods for random fill caching and prefetching for secure cache memories are provided. The system dynamically de-correlates fetching a cache line to the processor from filling the cache with this cache line, due to a demand memory access, in order to provide greater security from information leakage due to cache side-channel attacks on cache memories. The system includes a random fill engine which includes a random number generator and an adjustable random fill window. Also provided is an adaptive random fill caching system which dynamically adapts the random fill window to a wide variety of computational workloads. Systems and methods for cache prefetching to improve system performance using adaptive random fill prefetching and random fill prefetching are also provided. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/208825 |
| ART UNIT | 2133 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/14 (20130101) G06F 12/0802 (20130101) G06F 12/0862 (20130101) Original (OR) Class G06F 12/0868 (20130101) G06F 2212/602 (20130101) G06F 2212/1052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079334 | Mishra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Prabhat Kumar Mishra (Gainesville, Florida); Zhixin Pan (Gainesville, Florida) |
| ABSTRACT | The present disclosure provides systems and methods for test pattern generation to detect a hardware Trojan. One such method includes determining, by a computing device, a set of initial test patterns to activate the hardware Trojan within an integrated circuit design; evaluating nodes of the integrated circuit design and assigning a rareness attribute value and a testability attribute value associated with respective nodes of the integrated circuit design; and generating a set of additional test patterns to activate the hardware Trojan within the integrated circuit design using a reinforcement learning model. The set of initial test patterns is applied as an input along with rareness attribute values and testability attribute values associated with the nodes of the integrated circuit, and the reinforcement learning model is trained with a stochastic learning scheme to identify optimal test patterns for triggering nodes of the integrated circuit design. |
| FILED | Tuesday, December 07, 2021 |
| APPL NO | 17/543940 |
| ART UNIT | 2446 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 21/554 (20130101) Original (OR) Class G06F 2221/034 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
12079687 — Discrete frequency modulated gates for conditional logic in trapped ion quantum computers
| US 12079687 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Kenneth R. Brown (Durham, North Carolina); Pak Hong Leung (Durham, North Carolina); Shilin Huang (Durham, North Carolina); Bichen Zhang (Durham, North Carolina) |
| ABSTRACT | A system includes a controller configured to reconstitute a continuous waveform to a discrete analogue version. The system includes a numerical optimizer configured to determine frequencies of a pulse sequence. The numerical optimizer uses radial motional mode frequencies and a desired gate time. The numerical optimizer generates the pulse sequence by closing phase-space trajectories, disentangling spins and motions, and constraining a Rabi frequency for motional sideband transitions. The system also includes a display configured to illustrate a discrete frequency modulation pulse sequence based on the determined frequencies. |
| FILED | Thursday, March 25, 2021 |
| APPL NO | 17/212678 |
| ART UNIT | 2148 — Interprocess Communication and Software Development |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 3/026 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079723 | Sidhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tesla, Inc. (Austin, Texas) |
| ASSIGNEE(S) | Tesla, Inc. (Austin, Texas) |
| INVENTOR(S) | Harsimran Singh Sidhu (Fremont, California); Paras Jagdish Jain (Cupertino, California); Daniel Paden Tomasello (Los Altos Hills, California); Forrest Nelson Iandola (San Jose, California) |
| ABSTRACT | A model training and implementation pipeline trains models for individual embedded systems. The pipeline iterates through multiple models and estimates the performance of the models. During a model generation stage, the pipeline translates the description of the model together with the model parameters into an intermediate representation in a language that is compatible with a virtual machine. The intermediate representation is agnostic or independent to the configuration of the target platform. During a model performance estimation stage, the pipeline evaluates the performance of the models without training the models. Based on the analysis of the performance of the untrained models, a subset of models is selected. The selected models are then trained and the performance of the trained models are analyzed. Based on the analysis of the performance of the trained models, a single model is selected for deployment to the target platform. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/183515 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/027 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 1/0214 (20130101) G05D 1/0221 (20130101) Electric Digital Data Processing G06F 9/45533 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 3/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080506 | Mohammadi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Saeed Mohammadi (Zionsville, Indiana); Shabnam Ghotbi (Lafayette, Indiana) |
| ABSTRACT | A field emitter array (FEA) vacuum transistor is disclosed which includes a substrate and a plurality of nanorods formed of a first polarity dopant on the substrate. |
| FILED | Tuesday, September 05, 2023 |
| APPL NO | 18/242185 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 21/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080783 | Eom et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Chang-Beom Eom (Madison, Wisconsin); Tianxiang Nan (Ithaca, New York); Jonathon Schad (Madison, Wisconsin) |
| ABSTRACT | Voltage-controlled spin field effect transistors (“spin transistors”) and methods for their use in switching applications are provided. In the spin transistors, spin current is transported from a spin injection contact to a spin detection contact through a multiferroic antiferromagnetic channel via magnon propagation. The spin current transport is modulated by the application of a gate voltage that increases the number of domain boundaries the multiferroic antiferromagnetic material. |
| FILED | Thursday, March 05, 2020 |
| APPL NO | 16/809970 |
| ART UNIT | 2815 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/66984 (20130101) Original (OR) Class Electric solid-state devices not otherwise provided for H10N 50/20 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080801 | Seebauer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Edmund G. Seebauer (Urbana, Illinois) |
| ABSTRACT | A method of controlling oxygen vacancy concentration in a semiconducting metal oxide includes exposing a treated surface of a crystalline metal oxide to water at a temperature and pressure sufficient to maintain the water in a liquid phase. During the exposure, a portion of the water is adsorbed onto the treated surface and dissociates into atomic oxygen and hydrogen. The atomic oxygen is injected into and diffuses through the crystalline metal oxide, forming isolated oxygen interstitials and oxygen defect complexes. The isolated oxygen interstitials replace oxygen vacancies in the crystalline metal oxide. |
| FILED | Monday, January 10, 2022 |
| APPL NO | 17/571858 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 22/82 (20130101) C23C 22/83 (20130101) Non-mechanical Removal of Metallic Material From Surface; Inhibiting Corrosion of Metallic Material or Incrustation in General; Multi-step Processes for Surface Treatment of Metallic Material Involving at Least One Process Provided for in Class C23 and at Least One Process Covered by Subclass C21D or C22F or Class C25 C23F 1/30 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/32134 (20130101) H01L 21/67075 (20130101) H01L 27/1225 (20130101) H01L 29/7869 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12081450 | Cocker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | XEROX CORPORATION (Norwalk, Connecticut) |
| INVENTOR(S) | Eric D. Cocker (Redwood City, California); Matthew A. Shreve (Campbell, California); Francisco E. Torres (San Jose, California) |
| ABSTRACT | A system and method provide a combination of a modular message structure, a priority-based message packing scheme, and a data packet queue management system to optimize the information content of a transmitted message in, for example, the Ocean of Things (OoT) environment. The modular message structure starts with a header that provides critical information and reference points for time and location. The rest of the message is composed of modular data packets, each of which has a data ID section that the message decoder uses for reference when reconstructing the message contents, an optional size section that specifies the length of the following data section if it can contain data of variable length, and a data section that can be compressed in a manner unique to that data type. The message packing scheme uses a combination of priority level and minimum reporting interval, both of which are dynamically configurable for each data packet type, to maximize the value of the information contained in the modular data packets included in each message. Finally, the data packet queues manage temporary storage of data packets that have been generated but not yet included in an outgoing message. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/898985 |
| ART UNIT | 2478 — Multiplex and VoIP |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/022 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/06 (20130101) H04L 47/564 (20130101) H04L 47/6275 (20130101) Original (OR) Class H04L 69/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE50111 | Ghule et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Aditya N. Ghule (Madison, Wisconsin); Baoyun Ge (Madison, Wisconsin); Daniel Colin Ludois (Madison, Wisconsin) |
| ABSTRACT | A variable speed drive for an electrostatic motor provides feedback control by conversion of measured current phases provided to the motor into a vector in a rotating rotor framework. This vector is used for evaluating corrective voltages and then reconverted to a non-rotating framework for application to the motor electrodes. Current-source drive circuits provide current stabilized outputs making such sophisticated control tractable. |
| FILED | Thursday, June 07, 2018 |
| APPL NO | 16/003057 |
| ART UNIT | 3992 — Central Reexamination Unit (Electrical) |
| CURRENT CPC | Electric Machines Not Otherwise Provided for H02N 1/004 (20130101) H02N 1/008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12076748 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Panama) |
| INVENTOR(S) | Xianming Dai (University Park, Pennsylvania); Birgitt M. Boschitsch (University Park, Pennsylvania); Jing Wang (University Park, Pennsylvania); Tak-Sing Wong (University Park, Pennsylvania); Nan Sun (University Park, Pennsylvania) |
| ABSTRACT | Substrates having a textured surface that can maintain or improve droplet mobility in both the Cassie and Wenzel states include a textured surface and a conformal lubricant layer thereover. The textured surface can include a plurality of raised first elements and a plurality of second elements thereon and the conformal lubricant layer over the plurality of raised first elements and covering the plurality of second elements. The plurality of raised first elements can have an average height of between 0.5 μm and 500 μm, and the plurality of second elements can have an average height of between 0.01 μm and 10 μm. Such substrates can be prepared by texturing a surface of a substrate with a plurality of raised first elements and a plurality of second elements thereon; optionally silanizing the textured surface and applying a lubricant layer over the plurality of raised first elements and between the plurality of second elements. |
| FILED | Tuesday, August 27, 2019 |
| APPL NO | 16/551895 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/00 (20130101) B05D 3/101 (20130101) B05D 5/02 (20130101) B05D 5/08 (20130101) Original (OR) Class Cleaning in General; Prevention of Fouling in General B08B 17/065 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 59/022 (20130101) B29C 2059/023 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/0092 (20130101) B29K 2995/0093 (20130101) Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077055 | Asa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Erdem Asa (Oak Ridge, Tennessee); Veda Prakash Galigekere (Oak Ridge, Tennessee); Omer C. Onar (Oak Ridge, Tennessee); Burak Ozpineci (Oak Ridge, Tennessee); Jason L. Pries (Oak Ridge, Tennessee); Gui-Jia Su (Oak Ridge, Tennessee) |
| ABSTRACT | A method for wirelessly or conductively (non-wireless) providing AC or DC power in AC or DC load applications and bidirectional applications. |
| FILED | Monday, August 21, 2023 |
| APPL NO | 18/235961 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 53/60 (20190201) B60L 53/122 (20190201) Original (OR) Class B60L 2210/20 (20130101) B60L 2210/30 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0047 (20130101) H02J 50/12 (20160201) H02J 50/80 (20160201) H02J 2310/48 (20200101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 5/293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077520 | Sessler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF THE TEXAS SYSTEM (Austin, Texas); GYEONGSANG NATIONAL UNIVERSITY (Jinju-si, South Korea) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas); GYEONGSANG NATIONAL UNIVERSITY (Jinju-si, South Korea) |
| INVENTOR(S) | Jonathan L. Sessler (Austin, Texas); Qing He (Austin, Texas); Sung Kuk Kim (Jinju-si, South Korea) |
| ABSTRACT | The present disclosure relates to calixpyrrole compounds and compositions thereof. The calixpyrrole compounds are chemical groups which are located in such a manner so as to be useful for the selective extraction of specific salts. Also provided herein are compositions and methods of use thereof. |
| FILED | Thursday, May 23, 2019 |
| APPL NO | 17/057713 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Separation B01D 11/0492 (20130101) Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 15/04 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class C07D 471/04 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/36 (20210501) C22B 3/1666 (20130101) C22B 26/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077642 | Bertino et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| ASSIGNEE(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| INVENTOR(S) | Massimo Bertino (Glen Allen, Virginia); Sylwia Czlonka (Richmond, Virginia) |
| ABSTRACT | Polymeric aerogels, articles made from the polymeric aerogels and methods of making the polymeric aerogels are provided. The aerogels are made e.g. from crosslinkable monomers such as isocyanate monomers or phenolic monomers and a filler comprising crosslinkable hydroxyl groups. The filler may be natural (e.g. wood flour) or synthetic. The aerogels and products made therefrom exhibit low thermal conductivity and are mechanically strong. Due to their physical properties, these materials are used as e.g. building envelope components, such as walls, roofs and frames, to improve the thermal performance thereof, and may be used in a variety of other applications such as sound and insulation barriers in mechanical equipment, cryogenic containers, etc. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 17/059804 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/022 (20190201) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2075/00 (20130101) B29K 2105/16 (20130101) B29K 2105/0061 (20130101) B29K 2401/00 (20130101) B29K 2477/10 (20130101) B29K 2511/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 8/22 (20130101) C08G 18/18 (20130101) C08G 18/305 (20130101) C08G 18/792 (20130101) C08G 18/6492 (20130101) C08G 2110/0066 (20210101) C08G 2110/0083 (20210101) C08G 2110/0091 (20210101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/045 (20130101) Original (OR) Class C08J 9/28 (20130101) C08J 9/35 (20130101) C08J 9/0061 (20130101) C08J 9/0085 (20130101) C08J 9/0095 (20130101) C08J 2205/026 (20130101) C08J 2361/10 (20130101) C08J 2375/02 (20130101) C08J 2375/04 (20130101) C08J 2401/02 (20130101) C08J 2497/02 (20130101) Compositions of Macromolecular Compounds C08L 61/12 (20130101) C08L 75/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077672 | Perez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Lemuel Perez Perez (Livermore, California); Eric B. Duoss (Dublin, California); Jeremy Lenhardt (Tracy, California); Thomas S. Wilson (San Leandro, California) |
| ABSTRACT | A product of additive manufacturing with a silicone-based ink includes a plurality of continuous filaments comprised of a siloxane matrix, wherein the continuous filaments are arranged in a geometric pattern, a plurality of inter-filament pores defined by the geometric pattern of the continuous filaments, and a plurality of intra-filament pores having an average diameter in a range of greater than 1 micron to less than 50 microns. |
| FILED | Tuesday, October 12, 2021 |
| APPL NO | 17/499641 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/10 (20200101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/20 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/26 (20130101) C08J 2201/042 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/013 (20180101) C08K 3/36 (20130101) C08K 5/21 (20130101) C08K 7/22 (20130101) C08K 9/06 (20130101) C08K 2201/003 (20130101) C08K 2201/006 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/16 (20130101) Original (OR) Class C09D 11/101 (20130101) C09D 11/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
12077698 — Luminescent nanoparticle tracers, and systems and methods for fabrication and use thereof
| US 12077698 | Hubbard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Lance R. Hubbard (Richland, Washington); Ryan I. Sumner (Richland, Washington); Nicolas E. Uhnak (Kennewick, Washington); April J. Carman (Richland, Washington); Martin Liezers (Richland, Washington) |
| ABSTRACT | Ruggedized luminescent nanoparticle tracers have luminescent nanoparticle cores coupled to a luminescent substrate. The substrate is a large-particle size phosphor, while the nanoparticles are photoluminescent quantum dots (QDs) whose emission spectra can be tuned based on their chemical composition, size, and fabrication (e.g., dopants). The QDs are encapsulated by a protective layer to form a nanoparticle core. The protective layer can shield the QDs from external environments that would otherwise damage the delicate QDs. The substrate is also encapsulated by a protective layer, and the protective layer of the nanoparticle core is coupled to the protective layer of the substrate via a molecular linker to form a tracer particle complex. The tracer particle complexes can be disposed in a silicate suspension for subsequent use. |
| FILED | Wednesday, January 20, 2021 |
| APPL NO | 17/153178 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/025 (20130101) Original (OR) Class C09K 11/565 (20130101) C09K 11/574 (20130101) C09K 11/662 (20130101) C09K 11/883 (20130101) C09K 11/7745 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 2021/6439 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2991 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077719 | Myllenbeck et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Nicholas Myllenbeck (Livermore, California); Ryan Wesley Davis (San Jose, California); Eric Monroe (Melrose, Massachusetts); Joseph Carlson (Castro Valley, California) |
| ABSTRACT | A fuel for an internal combustion engine includes a C5 to C30 dialkoxyalkanoate corresponding to formula (I): wherein the R1 group is —H or a —CH3 group, the R2 and R2′ groups are alkyl groups independently selected to have 1 to 9 carbon atoms; and the R3 group is selected to have 1 to 9 carbon atoms. The compounds described herein may be used as neat fuels or mixed fuels (with diesel, biodiesel, jet fuel, marine fuel or other fuel compounds) in autoignition or spark ignition engines, such as diesel engines, gasoline (spark ignition) engines, MCCI, Homogeneous Charge Compression Ignition (HCCI) engines, or more generally in Low-Temperature Gasoline Combustion (LTGC) engines (using gasoline-like fuels), that have the high-efficiency advantages of HCCI but can operate with some level of charge inhomogeneities. Methods of making these compounds are environmentally friendly and can be done in a continuous manner. |
| FILED | Monday, October 03, 2022 |
| APPL NO | 17/958560 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 67/08 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/19 (20130101) Original (OR) Class C10L 10/12 (20130101) C10L 2200/0423 (20130101) C10L 2200/0446 (20130101) C10L 2270/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077874 | Corp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Twelve Benefit Corporation (Berkeley, California) |
| ASSIGNEE(S) | Twelve Benefit Corporation (Berkeley, California) |
| INVENTOR(S) | Kathryn L. Corp (Berkeley, California); Timothy A. Bekkedahl (Fremont, California); Kendra P. Kuhl (Oakland, California); Sichao Ma (Dublin, California); Gleb Smilyanski (Albany, California); Will Gasperini (Berkeley, California) |
| ABSTRACT | A method of forming a gas diffusion layer includes causing, at least in part, a stack of layers to be arranged between compressing surfaces of a press, the stack of layers including a plurality of gas diffusion layers. The method also includes causing, at least in part, the press to apply one or more compression cycles to the stack of layers to reduce a combined, uncompressed thickness of the plurality of gas diffusion layers between about 2% and about 30%. |
| FILED | Friday, April 14, 2023 |
| APPL NO | 18/300908 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 5/022 (20130101) B32B 5/024 (20130101) B32B 9/007 (20130101) B32B 9/041 (20130101) B32B 9/047 (20130101) B32B 15/14 (20130101) B32B 15/20 (20130101) B32B 27/12 (20130101) B32B 27/322 (20130101) B32B 37/06 (20130101) B32B 37/10 (20130101) B32B 38/0004 (20130101) B32B 2262/106 (20130101) B32B 2305/18 (20130101) B32B 2305/188 (20130101) B32B 2307/30 (20130101) B32B 2307/724 (20130101) B32B 2307/7376 (20230501) B32B 2309/02 (20130101) B32B 2309/04 (20130101) B32B 2309/12 (20130101) B32B 2311/04 (20130101) B32B 2311/08 (20130101) B32B 2311/12 (20130101) B32B 2311/24 (20130101) B32B 2313/04 (20130101) B32B 2327/18 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/26 (20210101) C25B 9/75 (20210101) C25B 9/77 (20210101) Original (OR) Class C25B 11/032 (20210101) C25B 13/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078084 | Terwilliger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Neil J. Terwilliger (Cheshire, Connecticut); Joseph B. Staubach (Colchester, Connecticut) |
| ABSTRACT | A turbine engine assembly includes a core engine that generates an exhaust gas flow, a condenser where water is extracted from the exhaust gas flow, an evaporator where heat is input into the water that is extracted by the condenser into a first steam flow, a steam turbine where the first steam flow is expanded and cooled, and a superheater where additional heat is input into the first steam flow that is exhausted from the steam turbine to generate a second steam flow. The second steam flow is injected into a core flow path of the core engine. |
| FILED | Friday, February 10, 2023 |
| APPL NO | 18/108336 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 7/223 (20130101) F01K 11/02 (20130101) Original (OR) Class F01K 15/02 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/72 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078350 | Hong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Cincinnati, Ohio) |
| INVENTOR(S) | Seung-Hyuck Hong (Clifton Park, New York); Richard L Hart (Broadalbin, New York); Honggang Wang (Clifton Park, New York); Anil Raj Duggal (Niskayuna, New York); Michael Anthony Benjamin (Cincinnati, Ohio) |
| ABSTRACT | A combustion section defines an axial direction, a radial direction, and a circumferential direction. The combustion section includes a casing that defines a diffusion chamber. A combustion liner is disposed within the diffusion chamber and defines a combustion chamber. The combustion liner is spaced apart from the casing such that a passageway is defined between the combustion liner and the casing. A fuel cell assembly is disposed in the passageway. The fuel cell assembly includes a fuel cell that extends between an inlet end and an outlet end. The inlet end receives a flow of air and fuel and the outlet end provides output products to the combustion chamber. The fuel cell extends at an angle between the inlet end and the outlet end relative to a radial projection line. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 17/984641 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) Original (OR) Class F23R 3/28 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/2457 (20160201) H01M 8/04089 (20130101) H01M 2250/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078385 | Martin |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Energy and Environmental Research Center Foundation (Grand Forks, North Dakota) |
| ASSIGNEE(S) | Energy and Environmental Research Center Foundation (Grand Forks, North Dakota) |
| INVENTOR(S) | Christopher Lee Martin (Grand Forks, North Dakota) |
| ABSTRACT | In various embodiments, the present invention relates to heat dissipation systems including a hygroscopic working fluid and methods of using the same. In various embodiments, the present invention provides a method for heat dissipation using a hygroscopic working fluid. The method can include transferring thermal energy from a heated process fluid to the hygroscopic working fluid in a process heat exchanger, to form a cooled process fluid. The method can include condensing liquid from a feed gas on a heat transfer surface of a feed gas heat exchanger in contact with the cooled process fluid, to form a cooled feed gas, the heated process fluid, and a condensate. The method can include dissipating thermal energy from the hygroscopic working fluid to a cooling gas composition with a fluid-air contactor. The method can include transferring moisture between the hygroscopic working fluid and the cooling gas composition with the fluid-air contactor. The method can include adding at least part of the condensate to the hygroscopic working fluid. |
| FILED | Monday, September 14, 2020 |
| APPL NO | 17/020718 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/143 (20130101) Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 3/1417 (20130101) Original (OR) Class Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 25/00 (20130101) Steam or Vapour Condensers F28B 9/06 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Come into Direct Contact Without Chemical Interaction F28C 1/02 (20130101) F28C 1/04 (20130101) F28C 1/16 (20130101) F28C 3/08 (20130101) F28C 2001/006 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/0034 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 23/02 (20130101) F28F 25/02 (20130101) F28F 25/087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078602 | Rose, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Paul B. Rose, Jr. (Oak Ridge, Tennessee); Jeremy Childress (Corvallis, Oregon) |
| ABSTRACT | A self-contained emitter assembly according to one embodiment is provided to generate and emit X-rays underwater for facilitating X-ray imaging. The self-contained emitter assembly may be operable by a user underwater without connection to an external power supply and/or control circuitry. |
| FILED | Monday, October 16, 2023 |
| APPL NO | 18/380464 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) Original (OR) Class G01N 23/083 (20130101) X-ray Technique H05G 1/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078656 | Kolski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jeffrey Kolski (Albuquerque, New Mexico); Erik Hurd (Edgewood, New Mexico); Robert L. Kinzel (Livermore, California) |
| ABSTRACT | A two-terminator RF adapter for background noise measurement in a test environment comprises a system test port comprising a system test port termination and a system test port connector to connect to a system under test; and a data acquisition port, comprising a data acquisition port termination and a data acquisition port connector to connect to a data acquisition system. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 17/399951 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 1/0416 (20130101) Original (OR) Class G01R 1/06788 (20130101) G01R 31/002 (20130101) G01R 31/52 (20200101) G01R 31/58 (20200101) Telephonic Communication H04M 1/24 (20130101) H04M 3/28 (20130101) H04M 3/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079159 | Agarwal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Sapan Agarwal (Cambridge, Massachusetts); Christopher Michael (Albuquerque, New Mexico); Matthew Marinella (Gilbert, Arizona) |
| ABSTRACT | A radiation-hardened (rad-hard) computing system can include a rad-hard processor, a second processor, and a memory operably coupled to the rad-hard processor. The rad-hard processor can cause the second processor to execute compute-intensive tasks that can be performed more quickly or with fewer computing resources by the second processor than the rad-hard processor. The rad-hard processor can selectively cause the second processor to execute a compute-intensive task based upon determining that the second processor is in a normal operating state. The rad-hard processor can further evaluate computing results generate by the second processor to determine whether such computing results meet an applicable acceptability condition. The rad-hard processor can employ a computing result that meets an applicable acceptability condition in further computing operations. |
| FILED | Wednesday, October 05, 2022 |
| APPL NO | 17/960291 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/16 (20130101) G06F 15/82 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079516 | Brewer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Tony M. Brewer (Plano, Texas); Dean E. Walker (Allen, Texas) |
| ABSTRACT | System and techniques for host-preferred memory operation are described herein. At a memory-side cache of a memory device that includes accelerator hardware, a first memory operation can be received from a host. A determination that the first memory operation corresponds to a cache set based on an address of the first memory operation is made. A second memory operation can be received from the accelerator hardware. Another determination can be made that the second memory operation corresponds to the cache set. Here, the first memory operation can be enqueued in a host queue of the cache set and the second memory operation can be enqueued in an internal request queue of the cache set. The first memory operation and the second memory operation can be executed as each is dequeued. |
| FILED | Tuesday, August 30, 2022 |
| APPL NO | 17/823314 |
| ART UNIT | 2138 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0607 (20130101) G06F 3/0659 (20130101) Original (OR) Class G06F 3/0679 (20130101) G06F 9/3877 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080111 | Borhan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | Cummins Inc. (Columbus, Indiana) |
| INVENTOR(S) | Hoseinali Borhan (Bloomington, Indiana) |
| ABSTRACT | A system includes a controller comprising at least one processor coupled to a memory storing instructions that, when executed by the at least one processor, cause the at least one processor to perform operations comprising: receiving information indicative of operation of the vehicle and of a driving condition for the vehicle; determining that a speed of the vehicle is less than a target speed for the vehicle based on the received information; determining, in response to the determination that the speed is less than the target speed, that the lane change and takeover event is at least one of feasible or efficient based on the received information; and providing, in response to the determination regarding the lane change and takeover event, a notification. |
| FILED | Monday, August 16, 2021 |
| APPL NO | 17/403189 |
| ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 35/00 (20130101) B60K 35/28 (20240101) B60K 2360/161 (20240101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080144 | Ahmed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GTI ENERGY (Des Plaines, Illinois) |
| ASSIGNEE(S) | GTI ENERGY (Des Plaines, Illinois) |
| INVENTOR(S) | Abdelallah Ahmed (Thousand Oaks, California); Jeffrey A. Mays (Woodland Hills, California); John C. Vega, III (Camarillo, California); Shinjiro Miyata (Malibu, California); David F. Morrison, II (Hesperia, California) |
| ABSTRACT | A system and method for communicating operation failure of a remote pipeline pneumatic device. A flow detector is used in combination with the pipeline pneumatic device. A controller in combination with the flow detector and a long range communication transmitter communicates an alarm upon detecting a predetermined flow, such as outside an expected amount. The controller can initiate a flow timer upon the actuation of the pneumatic device, and transmit an alarm upon the flow timer exceeding a predetermined value representing the expected amount. |
| FILED | Wednesday, August 31, 2022 |
| APPL NO | 17/899775 |
| ART UNIT | 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080318 | Candy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Jim Candy (Danville, California); Karl A. Fisher (Brentwood, California); Christopher Roland Candy (San Ramon, California) |
| ABSTRACT | A system determines an event location of an event within an indoor environment based on an event sound generated by the event. The system employs time-reversal techniques based on a received event sound to identify the event location as being in the vicinity of one of a plurality of locator devices at locator locations in the environment. The system includes a base array located within the environment that receives an indication that an event has been detected. Upon receiving the event sound, the system generates a time-reversed event sound for each transceiver and transmits via each transceiver the time-reversed event sound for that transceiver. When a locator device receives a time-reversed event sound, the locator device determines whether the event is in the vicinity of that locator location of the locator device and, if so, outputs an indication that the event occurred at that locator location. |
| FILED | Saturday, November 05, 2022 |
| APPL NO | 17/981412 |
| ART UNIT | RD00 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 21/04 (20130101) G10L 25/48 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0048 (20130101) H04L 65/70 (20220501) H04L 65/75 (20220501) Wireless Communication Networks H04W 4/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080362 | Raasch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| ASSIGNEE(S) | ADVANCED MICRO DEVICES, INC. (Santa Clara, California) |
| INVENTOR(S) | Steven Raasch (Boxborough, Massachusetts); Greg Sadowski (Boxborough, Massachusetts); David A. Roberts (Boxborough, Massachusetts) |
| ABSTRACT | Exemplary embodiments provide wear spreading among die regions (i.e., one or more circuits) in an integrated circuit or among dies by using operating condition data in addition to or instead of environmental data such as temperature data, from each of a plurality of die regions. Control logic produces a cumulative amount of time each of the plurality of die regions has spent at an operating condition based on operating condition data wherein the operating condition data is based on at least one of the following operating characteristics: frequency of operation of the plurality of die regions, an operating voltage of the plurality of die regions, an activity level of the plurality of die regions, a timing margin of the plurality of die regions, and a number of detected faults of the plurality of die regions. The method and apparatus spreads wear among the plurality of same type of die regions by controlling task execution among the plurality of die regions using the die wear-out data. |
| FILED | Friday, January 13, 2023 |
| APPL NO | 18/154372 |
| ART UNIT | 2191 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 3/064 (20130101) G06F 3/0616 (20130101) G06F 3/0679 (20130101) G06F 9/50 (20130101) G06F 12/0223 (20130101) G06F 12/0246 (20130101) G06F 2212/1036 (20130101) G06F 2212/7211 (20130101) Static Stores G11C 7/04 (20130101) G11C 11/4076 (20130101) G11C 16/349 (20130101) G11C 16/3418 (20130101) G11C 16/3495 (20130101) Original (OR) Class G11C 29/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080438 | Aleshin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | Yuriy Aleshin (Cayce, South Carolina); Alex Levinsky (Pittsburgh, Pennsylvania) |
| ABSTRACT | An adjustable core assembly for a nuclear reactor is disclosed herein. The adjustable core can include a plurality of reactivity control cells configured to accommodate a reactivity control rod, and a plurality of unit cells. The plurality of unit cells defines a radial dimension corresponding to an initial power output of the core. Each unit cell of the plurality of unit cells is configured to accommodate fuel configured to generate energy and a heat pipe configured to transfer thermal energy away from the core. Each unit cell of the plurality unit cells can be coupled to an adjacent unit cell in a radial direction, thereby altering the radial dimension, wherein the altered radial dimension corresponds to an adjusted power output of the core, and wherein the adjusted power output of the core is different than the initial power output of the core. |
| FILED | Thursday, October 29, 2020 |
| APPL NO | 17/084365 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 7/36 (20130101) G21C 7/103 (20130101) Original (OR) Class G21C 15/257 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080514 | Bloom et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Integrated Dynamic Electron Solutions, Inc. (Pleasanton, California) |
| ASSIGNEE(S) | INTEGRATED DYNAMIC ELECTRON SOLUTIONS, INC. (Pleasanton, California) |
| INVENTOR(S) | Ruth Shewmon Bloom (Oakland, California); Bryan Walter Reed (San Leandro, California); Daniel Joseph Masiel (Alamo, California); Sang Tae Park (Danville, California) |
| ABSTRACT | A device may include an electron source, a detector, and a deflector. The electron source may be directed toward a sample area. The detector may receive an electron signal or an electron-induced signal. A deflector may be positioned between the electron source and the sample. The deflector may modulate an intensity of the electron source directed to the sample area according to an electron dose waveform having a continuously variable temporal profile. |
| FILED | Wednesday, May 24, 2023 |
| APPL NO | 18/201536 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/28 (20130101) H01J 37/147 (20130101) H01J 37/243 (20130101) Original (OR) Class H01J 37/292 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080849 | Ashby et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | David Scott Ashby (Livermore, California); Albert Alec Talin (Dublin, California); Katharine Lee Harrison (Albuquerque, New Mexico) |
| ABSTRACT | An ionogel is formed by mixture of precursors, a catalyst, and an ionic liquid to form a sol-gel. The precursors and the catalyst react to form a solid-phase matrix that includes pores, wherein the ionic liquid is disposed within the pores. The gel is dried by way of thermal or vacuum drying to remove liquid byproducts of the precursor-catalyst reaction and to form a solid-state ionogel that comprises the solid-phase matrix with the ionic liquid disposed therein. The ionogel is immersed in a quantity of a liquid electrolyte that is soluble in the ionic liquid. As the liquid electrolyte dissolves into the ionic liquid, the ionic liquid is displaced by the liquid electrolyte, yielding an ionogel having the liquid electrolyte disposed within its pores. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 17/548872 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0565 (20130101) Original (OR) Class H01M 2300/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080860 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Zihua Zhu (Richland, Washington); Chongmin Wang (Richland, Washington) |
| ABSTRACT | Battery cells are provided that can include: a housing defining a chamber having a fluid inlet and outlet; an anode at one side of the housing; a cathode at another side of the housing opposing and spaced apart from the anode a sufficient amount to allow for electrolyte between the anode and cathode; and the other side of the chamber defined by an ion permeable member. Methods for in situ battery electrode analysis are provided and these methods can include: providing a battery cell having an anode and a cathode; exposing the battery cell to an ion beam while the battery cell is operational to form secondary ions; and detecting the secondary ions to analyze the battery. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/681503 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/2204 (20130101) G01N 27/447 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/134 (20130101) H01M 4/136 (20130101) H01M 4/382 (20130101) H01M 4/525 (20130101) H01M 4/661 (20130101) H01M 10/48 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 10/0569 (20130101) H01M 10/4285 (20130101) H01M 50/103 (20210101) H01M 50/131 (20210101) H01M 50/157 (20210101) H01M 50/172 (20210101) H01M 50/609 (20210101) H01M 2300/0025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080930 | Song et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ESS Tech, Inc. (Wilsonville, Oregon) |
| ASSIGNEE(S) | ESS TECH, INC. (Wilsonville, Oregon) |
| INVENTOR(S) | Yang Song (West Linn, Oregon); Kenneth Kiyoshi Fisher (Portland, Oregon); Timothy McDonald (Portland, Oregon) |
| ABSTRACT | A multi-chambered electrolyte storage tank for a redox flow battery system, may include first and second electrolyte chambers, and a bulkhead, wherein the first and second electrolyte chambers are fluidly coupled to first and second sides of a redox flow battery cell, respectively, the first and second electrolyte chambers include first and second liquid electrolyte volumes, respectively, and the first and second liquid electrolyte volumes are separated by the bulkhead positioned therebetween. In this way, manufacturing and operational complexity of a redox flow battery system can be reduced. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/456948 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) Original (OR) Class H01M 8/0202 (20130101) H01M 8/0289 (20130101) H01M 8/2455 (20130101) H01M 8/2484 (20160201) H01M 8/04037 (20130101) H01M 8/04097 (20130101) H01M 8/04201 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12081140 | Hawes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GE Energy Power Conversion Technology Limited (Warwickshire, United Kingdom) |
| ASSIGNEE(S) | GE Energy Power Conversion Technology Limited (Warwickshire, United Kingdom) |
| INVENTOR(S) | Nathaniel B. Hawes (Niskayuna, New York); Jovan Z. Bebic (Niskayuna, New York); Xiaohong Li (Niskayuna, New York) |
| ABSTRACT | Provided is a modular multilevel converter and a method for synchronizing outputs of sub-modules of the converter. The modular multilevel converter includes sub-modules connected in parallel, and each sub-module generates an output. The modular multilevel converter also includes a controller that is communicatively coupled to the sub-modules. The controller controls a flow of one or more synchronizing signals between the plurality of sub-modules, such that each sub-module receives the synchronizing signals in opposite directions simultaneously, thereby controlling a synchronization of the outputs generated by the sub-modules. |
| FILED | Wednesday, April 06, 2022 |
| APPL NO | 17/714992 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/493 (20130101) H02M 7/4835 (20210501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 12078459 | Vasudevan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Orbital Research Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Srikanth Vasudevan (Monroe, Connecticut); Paul Suchy (Parma, Ohio); Matthew C. Birch (Madison, Alabama) |
| ABSTRACT | Methods involve using a guided munition (e.g., a mortar round or a grenade) that utilizes deployable flow effectors, activatable flow effectors and/or active flow control devices to extend the range and enhance the precision of traditional unguided munitions without increasing the charge needed for launch. Sensors such as accelerometers, magnetometers, IR sensors, rate gyros, and motor controller sensors feed signals into a controller which then actuates or deploys the flow effectors/flow control devices to achieve the enhanced characteristics. |
| FILED | Thursday, November 10, 2022 |
| APPL NO | 17/984292 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Weapon Sights; Aiming F41G 7/222 (20130101) F41G 7/2253 (20130101) F41G 7/2293 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 10/14 (20130101) F42B 10/42 (20130101) F42B 10/44 (20130101) F42B 10/62 (20130101) F42B 15/01 (20130101) Original (OR) Class F42B 30/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078630 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PATH EX, Inc. (Houston, Texas) |
| ASSIGNEE(S) | PATH EX, INC. (Houston, Texas) |
| INVENTOR(S) | Sinead E. Miller (Houston, Texas); Jeffrey Ransden (Houston, Texas); Alan Bachman (Houston, Texas) |
| ABSTRACT | A device for the capture and adsorption of blood-borne materials of interest comprising a fluidic cartridge with at least one inlet and at least one outlet; a multidirectional fluidic channel between the at least one inlet and the at least one outlet; said multidirectional fluidic channel comprising at least one inner wall; and a substance coating at least a portion of the at least one inner wall of the multidirectional fluidic channel. |
| FILED | Tuesday, June 16, 2020 |
| APPL NO | 16/902745 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 2300/0854 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/492 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12079723 | Sidhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tesla, Inc. (Austin, Texas) |
| ASSIGNEE(S) | Tesla, Inc. (Austin, Texas) |
| INVENTOR(S) | Harsimran Singh Sidhu (Fremont, California); Paras Jagdish Jain (Cupertino, California); Daniel Paden Tomasello (Los Altos Hills, California); Forrest Nelson Iandola (San Jose, California) |
| ABSTRACT | A model training and implementation pipeline trains models for individual embedded systems. The pipeline iterates through multiple models and estimates the performance of the models. During a model generation stage, the pipeline translates the description of the model together with the model parameters into an intermediate representation in a language that is compatible with a virtual machine. The intermediate representation is agnostic or independent to the configuration of the target platform. During a model performance estimation stage, the pipeline evaluates the performance of the models without training the models. Based on the analysis of the performance of the untrained models, a subset of models is selected. The selected models are then trained and the performance of the trained models are analyzed. Based on the analysis of the performance of the trained models, a single model is selected for deployment to the target platform. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/183515 |
| ART UNIT | 2193 — Interprocess Communication and Software Development |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/027 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 1/0214 (20130101) G05D 1/0221 (20130101) Electric Digital Data Processing G06F 9/45533 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class G06N 3/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080505 | Bond, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | EngeniusMicro, LLC (Atlanta, Georgia) |
| ASSIGNEE(S) | EngeniusMicro, LLC (Atlanta, Georgia) |
| INVENTOR(S) | Arthur Gernt Bond, III (Auburn, Alabama); Benoit Hamelin (Atlanta, Georgia) |
| ABSTRACT | The present disclosure can relate to a thermionic emission device. The thermionic emission device can include a substrate layer, an insulating layer deposited onto an uppermost surface of the substrate layer, and an electron emitting layer deposited onto an uppermost surface of the insulating layer. The electron emitting layer, the insulating layer, and the substrate layer each can include a first etching and a second etching oriented according to a photoresist pattern applied to an uppermost surface of the electron emitting layer. The first etching and the second etching can converge to form a cavity in the substrate layer beneath a beam suspended above the cavity. The beam can comprise an unetched region of the electron emitting layer and the insulating layer oriented between the first etching and the second etching. |
| FILED | Thursday, January 04, 2024 |
| APPL NO | 18/404139 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 1/14 (20130101) H01J 1/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 12079127 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CoreSecure Technologies, LLC (Princeton, New Jersey) |
| ASSIGNEE(S) | Coresecure Technologies, LLC (Princeton, New Jersey) |
| INVENTOR(S) | Ruby B. Lee (Princeton, New Jersey); Fangfei Liu (Hillsboro, Oregon) |
| ABSTRACT | Systems and methods for random fill caching and prefetching for secure cache memories are provided. The system dynamically de-correlates fetching a cache line to the processor from filling the cache with this cache line, due to a demand memory access, in order to provide greater security from information leakage due to cache side-channel attacks on cache memories. The system includes a random fill engine which includes a random number generator and an adjustable random fill window. Also provided is an adaptive random fill caching system which dynamically adapts the random fill window to a wide variety of computational workloads. Systems and methods for cache prefetching to improve system performance using adaptive random fill prefetching and random fill prefetching are also provided. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/208825 |
| ART UNIT | 2133 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/14 (20130101) G06F 12/0802 (20130101) G06F 12/0862 (20130101) Original (OR) Class G06F 12/0868 (20130101) G06F 2212/602 (20130101) G06F 2212/1052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080048 | Fry |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Mark A. Fry (Marco Island, Florida) |
| ABSTRACT | Systems and methods of detecting a vortex made by a travelling object is disclosed. Techniques include positioning a media collector to capture a visual media file of the vortex. In some configurations, a graphic recognition algorithm and vortex similarity engine are used to determine whether a visual media file captured by a media collector contains a vortex. In some configurations, a computer may trigger an alert if a travelling object vortex is not expected to be in the visual media file. |
| FILED | Tuesday, November 15, 2022 |
| APPL NO | 17/987560 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/74 (20220101) G06V 10/761 (20220101) G06V 10/764 (20220101) Original (OR) Class G06V 10/7715 (20220101) G06V 20/52 (20220101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) Traffic Control Systems G08G 5/003 (20130101) G08G 5/0017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12081991 | Lim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Jason Lim (Alexandria, Virginia); Daniel Boyd (Arlington, Virginia); Chang Ellison (Arlington, Virginia); William Washington (North Potomac, Maryland) |
| ABSTRACT | In an example, a provider system receives from a client device a request for client access. The provider system sends to the client device a request for identification information of the client. The provider system receives client information associated with a mobile identification credential (MIC) which the client device received from an authorizing party system (APS), the client having consented to release the client information to the provider system, and the client information having been verified by the APS. The provider system uses the verified client information associated with the MIC to verify or not verify the identity of the client. The provider system verifies the identity of the client before granting the client the request for client access. |
| FILED | Wednesday, November 22, 2023 |
| APPL NO | 18/517807 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Wireless Communication Networks H04W 12/06 (20130101) H04W 12/08 (20130101) H04W 12/71 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 12076386 | Talaat |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Adel Mohamed Talaat (Madison, Wisconsin) |
| ABSTRACT | A composition and method for immunizing a mammal infected with Mycobacterium are disclosed. The genes gcpE, pstA, kdpC, papA2, impA, umaA1, fabG2_2, aceAB, mbtH2, lpqP, map0834c, cspB, lipN, or map1634 of M. paratuberculosis and their products that they encode are vaccine targets for Johne's and Crohn's disease. Eighteen M. paratuberculosis-specific genomic islands (MAPs) were identified. Three inverted large genomic fragments in M. paratuberculosis (INV) were also identified. These genomic identifiers represent novel virulence determinants that can be used as targets for vaccines and for developments of drugs against Johne's disease. The method can be used to deliver an immunizing compounds to a mammal, to provide an immune response against Johne's or Crohn's disease in the mammal. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 16/422336 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) A61K 39/04 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/552 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12077763 | Puralewski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Greenlight Biosciences, Inc. (Lexington, Massachusetts); United States of America, as represented by the Secretary of Agriculture (Beltsville, Maryland) |
| ASSIGNEE(S) | GREENLIGHT BIOSCIENCES, INC. (Lexington, Massachusetts); UNITED STATES, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Beltsville, Maryland) |
| INVENTOR(S) | Adriana Puralewski (Cary, North Carolina); Christopher Lawrence (Blacksburg, Virginia); Upendra Kumar Devisetty (Morrisville, North Carolina); Sambit Kumar Mishra (Cary, North Carolina); Krishnakumar Sridharan (Cary, North Carolina); Lance E. Cadle Davidson (Geneva, New York); Anna N. Underhill (Geneva, New York); Yufeng Fang (Durham, North Carolina); Wimalanathan Kokulapalan (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed herein are compositions and methods that involve recombinant polynucleotide molecules, such as single or double-stranded DNA or RNA molecules, also referred to “triggers”, that are useful for controlling or preventing E. necator infection, or recombinant DNA constructs for making such RNA molecules or for making transgenic grape plants resistant to E. necator infection. In some embodiments, polynucleotide triggers are provided as topically applied agents for controlling or preventing infection of a plant by E. necator. |
| FILED | Tuesday, March 08, 2022 |
| APPL NO | 17/689598 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/8218 (20130101) Original (OR) Class C12N 15/8286 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12078153 | Roberts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Scott N Roberts (Altadena, California); Sean W Reilly (Pasadena, California); Robert P Dillon (Costa Mesa, California); Benjamin I Furst (Pasadena, California); Dan M Goebel (Pasadena, California) |
| ABSTRACT | Systems and methods for embedding a thermal management system in an electric propulsion (EP) system is presented. According to one aspect, one or more oscillating heat pipes (OHPs) are provided within functional elements of the EP system. Each OHP includes channel segments that include a sealed working fluid. The channel segments are joined to form a continuous serpentine channel with a channel path that alternates between hot and cold regions of the EP system. According to another aspect, the functional elements of the EP system are reduced to a single monolithic structure with an embedded OHP. The single monolithic structure may be a single material or a multi material. According to yet another aspect, the functional elements are elements of a magnetic circuit of the EP system, including one or more of a backplate, an outer pole, an inner pole, or a center pole. |
| FILED | Thursday, April 14, 2022 |
| APPL NO | 17/721026 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0031 (20130101) Original (OR) Class F03H 1/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12081075 | Cantemir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio); Olivia Bruj (Columbus, Ohio) |
| ASSIGNEE(S) | Olivia Bruj (Cluj-Napoco, Romania); OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | Codrin Cantemir (Columbus, Ohio); Olivia Bruj (Cluj, Romania) |
| ABSTRACT | Improved electric machines with tuned coils, integrated power electronics, and stator and rotor cooling assemblies. |
| FILED | Monday, August 30, 2021 |
| APPL NO | 17/461956 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 1/20 (20130101) Original (OR) Class H02K 1/165 (20130101) H02K 3/12 (20130101) H02K 3/24 (20130101) H02K 3/28 (20130101) H02K 3/48 (20130101) H02K 5/203 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 12079893 | Punnoose et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Josen Punnoose (Crofton, Maryland); Sachin Agarwal (Washington, District of Columbia) |
| ABSTRACT | Generating authentication credentials includes receiving from a first user input identifying a customer identifier for an online account with a business or organization and a residential or business physical address, and sending via a network a notification to a first user system to follow instructions on a mail piece to be received by the first user. The mail piece is physically sent via a distribution network to the physical address and an online application is activated in response to scanning a coded indicia on the mail piece. Data indicative of an identity of the first user is received and the identity of the first user is verified based on at least information associated with the coded indicia and the received data. A recommendation is generated whether to approve the online account and an electronic credential is created for the first user based on acceptance of the online account. |
| FILED | Friday, October 13, 2023 |
| APPL NO | 18/486928 |
| ART UNIT | 2686 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 21/31 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 30/413 (20220101) Wireless Communication Networks H04W 4/029 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080092 | Simpson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Ryan J. Simpson (Vienna, Virginia) |
| ABSTRACT | Embodiments of a system and method for sorting and delivering articles in a processing facility based on image data are described. Image processing results such as rotation notation information may be included in or with an image to facilitate downstream processing such as when the routing information cannot be extracted from the image using an unattended system and the image is passed to an attended image processing system. The rotation notation information may be used to dynamically adjust the image before presenting the image via the attended image processing system. |
| FILED | Tuesday, May 24, 2022 |
| APPL NO | 17/664837 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/006 (20130101) B07C 3/20 (20130101) B07C 2301/0066 (20130101) B07C 2301/0075 (20130101) Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 2811/0673 (20130101) B65G 2811/0678 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1404 (20130101) Image or Video Recognition or Understanding G06V 10/242 (20220101) G06V 30/40 (20220101) G06V 30/413 (20220101) G06V 30/424 (20220101) Original (OR) Class G06V 30/1478 (20220101) Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus G07B 2017/00725 (20130101) Pictorial Communication, e.g Television H04N 1/0036 (20130101) H04N 1/00331 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 12080808 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peng Wu (Cambridge, Massachusetts); Joerg Appenzeller (West Lafayette, Indiana) |
| ABSTRACT | A cross-coupled tunnel diode (XTD) device with large peak-to-valley current ratio (PVCR) is disclosed. A memory cell circuit comprising XTD devices is also disclosed. The XTD device includes an N-type semiconductor coupled to a P-type semiconductor. A first gate is disposed on the N-type semiconductor and a second gate is disposed on the P-type semiconductor. The first gate is coupled to the output terminal, which is further coupled to the P-type semiconductor. The second gate is coupled to the input terminal, which is coupled to the N-type semiconductor. As reverse bias voltage increases, band-to-band tunneling from valence band to conduction band initially generates increasing current, but the rising bias voltage closes the band to band tunneling window, creating a gated negative differential resistance behavior. The current drops off as the bias voltage further increases. In some examples, a ratio of peak-to-valley current ratio may exceed 103 or 105. |
| FILED | Wednesday, March 09, 2022 |
| APPL NO | 17/690417 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/88 (20130101) Original (OR) Class Electronic Memory Devices H10B 10/00 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 12077642 | Bertino et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| ASSIGNEE(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| INVENTOR(S) | Massimo Bertino (Glen Allen, Virginia); Sylwia Czlonka (Richmond, Virginia) |
| ABSTRACT | Polymeric aerogels, articles made from the polymeric aerogels and methods of making the polymeric aerogels are provided. The aerogels are made e.g. from crosslinkable monomers such as isocyanate monomers or phenolic monomers and a filler comprising crosslinkable hydroxyl groups. The filler may be natural (e.g. wood flour) or synthetic. The aerogels and products made therefrom exhibit low thermal conductivity and are mechanically strong. Due to their physical properties, these materials are used as e.g. building envelope components, such as walls, roofs and frames, to improve the thermal performance thereof, and may be used in a variety of other applications such as sound and insulation barriers in mechanical equipment, cryogenic containers, etc. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 17/059804 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/022 (20190201) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2075/00 (20130101) B29K 2105/16 (20130101) B29K 2105/0061 (20130101) B29K 2401/00 (20130101) B29K 2477/10 (20130101) B29K 2511/10 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 70/00 (20141201) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 8/22 (20130101) C08G 18/18 (20130101) C08G 18/305 (20130101) C08G 18/792 (20130101) C08G 18/6492 (20130101) C08G 2110/0066 (20210101) C08G 2110/0083 (20210101) C08G 2110/0091 (20210101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/045 (20130101) Original (OR) Class C08J 9/28 (20130101) C08J 9/35 (20130101) C08J 9/0061 (20130101) C08J 9/0085 (20130101) C08J 9/0095 (20130101) C08J 2205/026 (20130101) C08J 2361/10 (20130101) C08J 2375/02 (20130101) C08J 2375/04 (20130101) C08J 2401/02 (20130101) C08J 2497/02 (20130101) Compositions of Macromolecular Compounds C08L 61/12 (20130101) C08L 75/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 12077812 | Feinstein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | The United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia); The Board Of Trustees Of The University Of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Douglas Feinstein (Chicago, Illinois); Anne Boullerne (Chicago, Illinois) |
| ABSTRACT | Disclosed herein, are methods of detecting multiple sclerosis in a subject by measuring relative abundances of multiple oral microbiota in sample. Also, disclosed herein are methods of treatment and prophylaxis of MS. |
| FILED | Thursday, April 07, 2022 |
| APPL NO | 17/715187 |
| ART UNIT | 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 12079345 | Stolfo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Salvatore J. Stolfo (New York, New York); Preetam Kumar Dutta (New York, New York) |
| ABSTRACT | Methods, systems, and media for testing insider threat detection systems are provided. In some embodiments, the method comprises: receiving, using a hardware processor, a first plurality of actions in a computing environment that are associated with one of a plurality of user accounts; generating a plurality of models of user behavior based at least in part on the first plurality of actions, wherein each of the plurality of models of user behavior is associated with each of the plurality of user accounts; selecting a model of user behavior from the plurality of models of user behavior, wherein the model of user behavior is associated with a malicious user type; generating a simulated user bot based on the selected model of user behavior; executing the simulated user bot in the computing environment, wherein the simulated user bot injects a second plurality of actions in the computing environment; determining whether an insider threat detection system executing within the computing environment identifies the simulated user bot as a malicious user; and transmitting a notification indicating an efficacy of the insider threat detection system based on the determination. |
| FILED | Tuesday, October 26, 2021 |
| APPL NO | 17/511253 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class G06F 2221/034 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/306 (20130101) H04L 67/535 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 12078073 | Phelps |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Joseph B. Phelps (Rocky Hill, Connecticut) |
| ABSTRACT | An assembly is provided for a turbine engine. This turbine engine assembly includes a rotating assembly and a sensor. The rotating assembly is configured to rotate about an axis. The rotating assembly includes an engine shaft, a phonic wheel and a lubricant scoop. The phonic wheel is mounted onto the engine shaft. The phonic wheel includes an outer surface and a plurality of apertures arranged circumferentially about the axis. Each of the apertures projects at least partially radially into the phonic wheel from the outer surface. The lubricant scoop is radially outboard of and axially overlaps the outer surface. The sensor is configured to measure fluctuations in a magnetic field induced by the phonic wheel during rotation of the rotating assembly about the axis. |
| FILED | Friday, May 26, 2023 |
| APPL NO | 18/202754 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 21/003 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2270/80 (20130101) F05D 2270/304 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 3/481 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12078454 | Ferren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cubic Corporation (San Diego, California) |
| ASSIGNEE(S) | Cubic Defense Applications, Inc. (San Diego, California) |
| INVENTOR(S) | Bran Ferren (Beverly Hills, California); Colton O'Connor (Los Angeles, California); Robert Liebersbach (Glendale, California); Julian Brooks (Los Angeles, California); Clinton Hope (Los Angeles, California); Houstin Lee Lichtenwalner, Jr. (Emmaus, Pennsylvania) |
| ABSTRACT | A laserless combat simulation device includes at least one processing device and a memory device having instructions stored thereon that, when executed by the at least one processing device cause the at least one processing device to receive a trigger event from a weapon device. The instructions further cause the at least one processing device to receive image data from an optical sensor array of the weapon device of a field of view of the weapon device, receive position information and orientation information of the weapon device at the time of the trigger event, analyze the image data to determine an identity and location of a target, and calculate a ballistic outcome based at least in part on the position information and orientation information of the weapon device, the identity and location of the target, and ballistic characteristics of a simulated round fired from the weapon device. |
| FILED | Friday, August 14, 2020 |
| APPL NO | 16/994345 |
| ART UNIT | 3715 — Amusement and Education Devices |
| CURRENT CPC | Weapon Sights; Aiming F41G 3/26 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/51 (20130101) Image Data Processing or Generation, in General G06T 7/70 (20170101) Image or Video Recognition or Understanding G06V 20/10 (20220101) G06V 2201/07 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12080473 | Rackson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Gary M. Rackson (Pasadena, Maryland) |
| ABSTRACT | In some examples, an isolation transformer can include a first wire having a first insulation thickness and a second wire having a second insulation thickness that is different than the first insulation thickness. The isolation transformer can further include a plurality of magnetic cores of magnetic material that can be configured to surround portions of each of the first and second wires along respective circumferences of the first and second wires to provide the isolation transformer. |
| FILED | Monday, August 14, 2023 |
| APPL NO | 18/449573 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/24 (20130101) H01F 27/32 (20130101) Original (OR) Class H01F 27/2823 (20130101) H01F 41/12 (20130101) H01F 41/063 (20160101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 03, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
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FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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