FedInvent™ Patents
Patent Details for Tuesday, September 10, 2024
This page was updated on Tuesday, September 17, 2024 at 06:57 AM GMT
Department of Health and Human Services (HHS)
| US 12082883 | Frisken et al. |
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| FUNDED BY |
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| APPLICANT(S) | Canon U.S.A., Inc. (Melville, New York); The Brigham and Women's Hospital Incorporated (Boston, Massachusetts); Sarah Frisken (Cambridge, Massachusetts); Clement Mirabel (Brookline, Massachusetts); Parikshit Juvekar (Brookline, Massachusetts); Takahisa Kato (Brookline, Massachusetts); Alexandra J. Golby (Jamaica Plain, Massachusetts); Garth R. Cosgrove (Boston, Massachusetts); Thomas Noh (Boston, Massachusetts) |
| ASSIGNEE(S) | Canon U.S.A., Inc. (Melville, New York); The Brigham and Women's Hospital Incorporated (Boston, Massachusetts) |
| INVENTOR(S) | Sarah Frisken (Cambridge, Massachusetts); Clement Mirabel (Brookline, Massachusetts); Parikshit Juvekar (Brookline, Massachusetts); Takahisa Kato (Brookline, Massachusetts); Alexandra J. Golby (Jamaica Plain, Massachusetts); Garth R. Cosgrove (Boston, Massachusetts); Thomas Noh (Boston, Massachusetts) |
| ABSTRACT | Exemplary methods and systems that provide a curved path trajectory that can be used with a bendable medical device. The curved pathway can comprise straight and curved concatenated arc segments. The methods and systems can provide planning, visualizing and treatment of, for example, temporal lobe epilepsy (TLE) using laser interstitial thermal therapy (LITT) or tumors using ablation therapy. With curved pathway, the physician can create plan for intervention to avoid critical structure and to cover more target volume for treatment/diagnosis than straight pathway. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/791168 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) Original (OR) Class A61B 34/20 (20160201) A61B 2034/105 (20160201) A61B 2034/107 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12082905 | Henry et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Thomas R. Henry (Minneapolis, Minnesota); Gregory F. Molnar (Minneapolis, Minnesota); Michael C. Park (Minneapolis, Minnesota); Pierre-Francois Van De Moortele (Minneapolis, Minnesota) |
| ABSTRACT | Ultra-high field (“UHF”) magnetic resonance imaging (“MRI”) is used to localize the endopiriform nucleus (“EPN”) as a target for neuromodulation treatment. Single or multiple different image contrasts can be used to guide localization of the EPN. Treatment plan data are generated based on the localized EPN, and may include coordinate data, trajectory data, or both, for delivering neuromodulation treatment to the localized EPN. |
| FILED | Monday, October 05, 2020 |
| APPL NO | 17/766420 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0036 (20180801) A61B 5/0042 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12082916 | Does et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Mark D. Does (Nashville, Tennessee); John A. Rogers (Wilmette, Illinois) |
| ABSTRACT | An implantable bioresorbable radio frequency (RF) coil for high-resolution and high-specificity post-surgical evaluating or monitoring with magnetic resonance imaging (MRI) is disclosed. The coil includes a bioresorbable conductor configured to be resorbed within a patient while the coil is implanted in the patient. In one embodiment, the target application of this coil is the evaluation or monitoring (via MRI) of peripheral nerve regeneration following surgical repair. |
| FILED | Monday, March 01, 2021 |
| APPL NO | 17/798193 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/05 (20130101) Original (OR) Class A61B 5/055 (20130101) A61B 2505/05 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083067 | Behboodi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ahad Behboodi (Newark, Delaware); Samuel C. K. Lee (Fork, Maryland); Stuart A. Binder-Macleod (Newark, Delaware); Henry Wright (Lincoln University, Pennsylvania) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Ahad Behboodi (Newark, Delaware); Samuel C. K. Lee (Fork, Maryland); Stuart A. Binder-Macleod (Newark, Delaware); Henry Wright (Lincoln University, Pennsylvania) |
| ABSTRACT | A modular artificial skeletal muscle (MASM) actuator having a plurality of dielectric elastomer units assembled in series or in parallel. A proximal anchoring member is connected to a proximal end of at least one proximal dielectric elastomer unit and is configured for attachment to a proximal anchor point relative to a user. A tension member has a proximal end attached to a distal end of at least one distal dielectric elastomer unit and a distal end configured for attachment to a distal anchor point relative to the user. A controller is configured to cause simultaneous contraction or expansion of plurality of dielectric elastomer units, which contraction or expansion causes displacement of the tension member. A plurality of MASM actuators may be attached to an exoskeleton attached about an ankle of a user and controlled for therapeutic purposes, such as for assisting pediatric patients with cerebral palsy. |
| FILED | Thursday, December 10, 2020 |
| APPL NO | 17/117904 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/0127 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 3/00 (20130101) Original (OR) Class A61H 2201/1207 (20130101) A61H 2201/1642 (20130101) A61H 2201/1652 (20130101) A61H 2203/0406 (20130101) A61H 2205/06 (20130101) A61H 2205/12 (20130101) A61H 2230/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083098 | Tucker et al. |
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| APPLICANT(S) | Actuate Therapeutics Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | ACTUATE THERAPEUTICS INC. (Fort Worth, Texas) |
| INVENTOR(S) | Torry A. Tucker (Tyler, Texas); Steven Idell (Tyler, Texas) |
| ABSTRACT | Pharmaceutical compositions and methods are described which rely upon glycogen synthase kinase 3 (form β; GSK 3 β) inhibitors, most preferably 9-ING-41, to inhibit fibrotic pulmonary remodeling in vivo including proliferation and differentiation of myofibroblasts to fibrotic fibroblasts in several mouse models. Therapeutic targeting of GSK-3β with the clinically useful specific inhibitor, 9-ING-41, mitigates fibrotic pulmonary remodeling in vivo and provides a mode of therapy of human IPF by specific GSK-3β inhibition with 9-ING-41. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 17/056238 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0073 (20130101) A61K 31/407 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083105 | Sharma et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Manu Sharma (Tappan, New York); Nima N. Naseri (Philadelphia, Pennsylvania) |
| ABSTRACT | The present technology relates to methods for treating, preventing, and/or ameliorating diseases associated with ectopic iron-sulfur (Fe—S) cluster formation or ectopic iron-sulfur (Fe—S) cluster binding, such as adult-onset neuronal ceroid lipofuscinosis (ANCL or Kufs disease) comprising administering a therapeutically effective amount of an iron chelator to a subject in need thereof. Kits for use in practicing the methods are also provided. |
| FILED | Friday, January 22, 2021 |
| APPL NO | 17/155200 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 9/0073 (20130101) A61K 31/16 (20130101) A61K 31/44 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083109 | Anderson et al. |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | David J. Anderson (Altadena, California); Moriel Zelikowsky (Pasadena, California); Andrea Choe (Los Angeles, California) |
| ABSTRACT | In some embodiments, methods of inhibiting, ameliorating, reducing the severity of, treating, reducing the likelihood of, or preventing social isolation stress or symptoms thereof in a subject in need thereof are described. In some embodiments, methods of determining a risk of social isolation stress in a subject are described. |
| FILED | Friday, September 30, 2022 |
| APPL NO | 17/937067 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4545 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 43/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083113 | Silverman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); Chapman University (Orange, California) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Chapman University (Orange, California) |
| INVENTOR(S) | Richard B. Silverman (Winnetka, Illinois); Sun Yang (Lake Forest, California) |
| ABSTRACT | Disclosed herein are methods and compositions for administering immunotherapy to a subject in need thereof and for treating a subject in need thereof, where in the methods the subject is administered an effective amount of an inhibitor of nNOS for inducing an immunotherapeutic response in the subject and for treating the subject. The disclosed methods and composition may be utilized for treating a subject having a cell proliferative disease or disorder such as melanoma. |
| FILED | Monday, September 12, 2022 |
| APPL NO | 17/942928 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) Original (OR) Class A61K 31/381 (20130101) A61K 31/495 (20130101) A61K 31/4164 (20130101) A61K 38/212 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083123 | Sasaki et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Cincinnati (Cincinnati, Ohio); Children's Hospital Los Angeles (Los Angeles, California) |
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| INVENTOR(S) | Atsuo Sasaki (Cincinnati, Ohio); Mikako Warren (Pasadena, California) |
| ABSTRACT | The present disclosure concerns methods of detecting injury to a tissue and/or organ in a subject. In some aspects, the subject is the recipient of a transplant, such as a liver transplant. In some aspects, the subject is undergoing treatment with an immunosuppressant. In some aspects, the present disclosure concerns the identification of aberrant mitochondria in the subject to identify injury to the tissue and/or organ of the subject. Detecting aberrant mitochondria allows for remedial and/or corrective action to prevent or avoid significant injury. |
| FILED | Wednesday, October 06, 2021 |
| APPL NO | 17/494968 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/5377 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083125 | Walker et al. |
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| FUNDED BY |
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| APPLICANT(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Janice L. Walker (Philadelphia, Pennsylvania); Alexander Mazo (Cherry Hill, New Jersey); Svetlana Petruk (Voorhees, New Jersey); A. Sue Menko (Merion Station, Pennsylvania) |
| ABSTRACT | A therapeutic treatment for preventing or reducing the formation of fibrosis comprising administering to a patient a UTX or JMJD3 inhibitor that are effective in preventing or reducing fibrosis in situations wherein access to an injury or dysmorphogenetic tissues before the fibrotic process becomes established in the tissues. |
| FILED | Thursday, July 07, 2022 |
| APPL NO | 17/859082 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0048 (20130101) A61K 9/0051 (20130101) A61K 31/55 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083132 | Quave et al. |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
| INVENTOR(S) | Cassandra L. Quave (Atlanta, Georgia); James Lyles (Sandy Springs, Georgia); Gina Porras-Brenes (Atlanta, Georgia); Huaqiao Tang (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to extracts from the Anacardiaceae (cashew plant family) and compositions comprising compounds contained therein. In certain embodiments, the extracts are derived from the fruit of a Schinus plant. In certain embodiments, the disclosure relates to methods of treating or preventing bacterial infections, acne, and other related uses. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/121280 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/575 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083137 | Holstein et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska); UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| ASSIGNEE(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska); UNIVERSITY OF IOWA RESEARCH FOUNDATION (Iowa City, Iowa) |
| INVENTOR(S) | Sarah Holstein (Omaha, Nebraska); David Wiemer (Iowa City, Iowa) |
| ABSTRACT | Disclosed herein are inhibitors of the GGDPS enzyme, and methods for their use in treating or preventing diseases, such as multiple myeloma. The inhibitors described herein can include compounds of Formula (I) and pharmaceutically acceptable salts thereof: wherein the substituents are described. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/332324 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/683 (20130101) Original (OR) Class A61K 45/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6518 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083139 | Alberini et al. |
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| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Cristina Maria Alberini (New York, New York); Dirk Trauner (New York, New York); Christopher James Arp (The Woodlands, Texas) |
| ABSTRACT | Provided are methods for treatment of neurodevelopmental disorders, such as Angelman Syndrome and autism comprising administering to an individual a composition comprising an agonist ligand of IGF-2 receptor. The agonist ligand of IGF-2 receptor may be IGF-2, or mannose-6-phosphate or a derivative thereof. Compositions comprising mannose-6-phosphate derivatives are also disclosed. |
| FILED | Monday, August 12, 2019 |
| APPL NO | 17/267715 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7024 (20130101) Original (OR) Class A61K 38/30 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083143 | Kant et al. |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Shashi Kant (Shrewsbury, Massachusetts); Siobhan Craige (Christiansburg, Virginia); John F. Keaney, Jr. (Hingham, Massachusetts); Roger J. Davis (Princeton, Massachusetts) |
| ABSTRACT | Methods for treating cancer, and for reducing angiogenesis in a tissue, comprising administering one or more of a miR-371 oligonucleotide; a miR-146 oligonucleotide; or an inhibitor of MLK2/3 activity. |
| FILED | Friday, April 05, 2019 |
| APPL NO | 17/045327 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/553 (20130101) A61K 31/713 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) C12N 2310/141 (20130101) C12N 2320/30 (20130101) C12N 2320/31 (20130101) Enzymes C12Y 207/11025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083144 | Ray et al. |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Anuradha Ray (Pittsburgh, Pennsylvania); Prabir Ray (Pittsburgh, Pennsylvania); Sally Ellen Wenzel (Pittsburgh, Pennsylvania); Timothy B. Oriss (Pittsburgh, Pennsylvania) |
| ABSTRACT | Methods are provided for treating corticosteroid-resistant asthma in a patient, comprising decreasing Interferon Regulatory Factor 5 (IRF5) activity in the patient. Antisense or RNA interference reagents and methods can be used to decrease IRF5 activity in the patient. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/466454 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083145 | Zager et al. |
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| FUNDED BY |
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| APPLICANT(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Richard A. Zager (Seattle, Washington); Ali C M Johnson (Mill Creek, Washington) |
| ABSTRACT | The present disclosure provides compositions, kits, and methods to protect organs by inducing acquired cytoresistance without causing injury to the organ. The compositions, kits, and methods utilize heme proteins, iron and/or vitamin B12 and, optionally, agents that impact heme protein metabolism. |
| FILED | Tuesday, September 12, 2023 |
| APPL NO | 18/465768 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/194 (20130101) A61K 31/555 (20130101) A61K 31/714 (20130101) Original (OR) Class A61K 33/26 (20130101) A61K 38/42 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083148 | Abate-Daga |
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| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| INVENTOR(S) | Daniel Abate-Daga (Tampa, Florida) |
| ABSTRACT | Disclosed herein are chimeric antigen receptor (CAR) polypeptides that can be used with adoptive cell transfer to target and kill IL13Ra2-expressing cancers. Also disclosed are immune effector cells, such as T cells or Natural Killer (NK) cells, that are engineered to express these CARs. Therefore, also disclosed are methods of providing an anti-tumor immunity in a subject with an IL13Ra2-expressing cancer that involves adoptive transfer of the disclosed immune effector cells engineered to express the disclosed CARs. |
| FILED | Thursday, February 22, 2018 |
| APPL NO | 16/487367 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Peptides C07K 14/7051 (20130101) C07K 14/7155 (20130101) C07K 16/2866 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083158 | Bond et al. |
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| FUNDED BY |
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| APPLICANT(S) | MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia) |
| ASSIGNEE(S) | Morehouse School of Medicine (Atlanta, Georgia) |
| INVENTOR(S) | Vincent Craig Bond (Stone Mountain, Georgia); Michael Powell (Douglasville, Georgia); Ming Bo Huang (Atlanta, Georgia); Syed Ali (New Iberia, Louisiana); Martin N. Shelton (Seattle, Washington) |
| ABSTRACT | Compositions and methods for reducing the growth of and/or preventing the formation of a microbial biofilm are disclosed. The composition comprises an antimicrobial SMR peptide comprising an HIV-1 SMRwt peptide and a cell penetrating peptide (CPP) domain. In some embodiments, the composition further comprises one or more other antimicrobial peptides (AMPs), antibiotics, matrix-inhibiting compounds, matrix-disaggregating compounds, quorum sensing inhibitors, or a combination thereof. In other embodiments, the compositions are used for impregnating or coating an article and/or material surface with the composition to render it less prone to microbial infections. |
| FILED | Wednesday, December 19, 2018 |
| APPL NO | 16/226242 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 38/162 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/60 (20170801) A61K 47/6455 (20170801) Peptides C07K 7/06 (20130101) C07K 14/005 (20130101) C07K 2319/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16032 (20130101) C12N 2740/16322 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083159 | Bond et al. |
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| FUNDED BY |
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| APPLICANT(S) | MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia) |
| ASSIGNEE(S) | MOREHOUSE SCHOOL OF MEDICINE (Atlanta, Georgia) |
| INVENTOR(S) | Vincent Craig Bond (Stone Mountain, Georgia); Michael Powell (Douglasville, Georgia); Ming Bo Huang (Atlanta, Georgia); Syed Ali (New Iberia, Louisiana); Martin N. Shelton (Seattle, Washington) |
| ABSTRACT | Compositions and methods for reducing the growth of and/or preventing the formation of a microbial biofilm are disclosed. The composition comprises an antimicrobial SMR peptide comprising an HIV-1 SMRwt peptide and a cell penetrating peptide (CPP) domain. In some embodiments, the composition further comprises one or more other antimicrobial peptides (AMPs), antibiotics, matrix-inhibiting compounds, matrix-disaggregating compounds, quorum sensing inhibitors, or a combination thereof. In other embodiments, the compositions are used for impregnating or coating an article and/or material surface with the composition to render it less prone to microbial infections. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 16/811754 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 38/162 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/60 (20170801) A61K 47/6455 (20170801) Peptides C07K 7/06 (20130101) C07K 14/005 (20130101) C07K 2319/10 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16032 (20130101) C12N 2740/16322 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083168 | Zuchner et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Miami (Miami, Florida); University of Rochester (Rochester, New York); UCL Business LTD (London, United Kingdom) |
| ASSIGNEE(S) | University of Miami (Miami, Florida); University of Rochester (Rochester, New York); UCL Business LTD (London, United Kingdom) |
| INVENTOR(S) | Stephan L. Zuchner (Miami, Florida); Adriana Rebelo (Miami, Florida); Andrea Cortese (London, United Kingdom); Rong Grace Zhai (Miami, Florida); David N. Herrmann (Rochester, New York) |
| ABSTRACT | The present disclosure relates to methods of detecting and treating inherited neuropathy. |
| FILED | Wednesday, April 13, 2022 |
| APPL NO | 17/719580 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/198 (20130101) A61K 31/352 (20130101) A61K 31/426 (20130101) A61K 31/428 (20130101) A61K 31/473 (20130101) A61K 31/499 (20130101) A61K 31/502 (20130101) A61K 31/517 (20130101) A61K 31/4184 (20130101) A61K 31/4188 (20130101) A61K 31/7105 (20130101) A61K 38/443 (20130101) Original (OR) Class A61K 38/465 (20130101) A61K 48/005 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 15/86 (20130101) C12N 15/1137 (20130101) C12N 2310/11 (20130101) C12N 2750/14143 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 101/01014 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/66 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083181 | Spiegel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); David Caianiello (New Haven, Connecticut) |
| ABSTRACT | Described herein is a bi-functional compound for removing macrophage migration inhibitory factor (MIF) or immunoglobulin G (IgG). Further described herein is a pharmaceutical composition which comprise these bi-functional compounds. Further described herein is a method for treating disease states and/or conditions with the compounds or the composition. The disease states and/or conditions are mediated through MIF/IgG or where MIF/IgG is a contributing factor to the development and perpetuation of diseases and/or conditions, such as autoimmune diseases and cancer, among others. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/161633 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/55 (20170801) Original (OR) Class A61K 47/545 (20170801) A61K 47/549 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083185 | Sun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Jingjing Sun (Pittsburgh, Pennsylvania); Song Li (Mars, Pennsylvania) |
| ABSTRACT | A polymer includes a hydrophobic polymer backbone, a first plurality of pendant groups attached to the hydrophobic polymer backbone and including at least one group including a plurality of hydroxyl groups, and a second plurality of pendant groups attached to the hydrophobic polymer backbone and comprising at least one hydrophilic polymer. |
| FILED | Friday, October 11, 2019 |
| APPL NO | 17/284562 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 31/12 (20130101) A61K 31/138 (20130101) A61K 31/337 (20130101) A61K 31/366 (20130101) A61K 31/404 (20130101) A61K 31/405 (20130101) A61K 31/436 (20130101) A61K 31/506 (20130101) A61K 31/551 (20130101) A61K 31/7068 (20130101) A61K 38/13 (20130101) A61K 47/54 (20170801) A61K 47/58 (20170801) A61K 47/60 (20170801) A61K 47/542 (20170801) A61K 47/6907 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083191 | Basilion et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | James Basilion (Shaker Heights, Ohio); Kirti Dhingra (Cleveland, Ohio); Thomas J. Meade (Evanston, Illinois); Sarah Grace Kamper (Evanston, Illinois) |
| ABSTRACT | A composition for imaging a cell includes a first imaging probe and a second imaging probe that include respectively a first reporter moiety and a second reporter moiety. The first reporter moiety and the second reporter moiety form a signaling complex that produces a detectable signal when the first imaging probe and second imaging probe complex with first and second biomarkers of the cell. |
| FILED | Tuesday, September 17, 2019 |
| APPL NO | 16/573570 |
| ART UNIT | RD00 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/14 (20130101) A61K 49/0017 (20130101) A61K 49/085 (20130101) A61K 49/1881 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083246 | Horkay et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Ferenc Horkay (North Potomac, Maryland); Peter Joel Basser (Washington, District of Columbia) |
| ABSTRACT | A self-reinforcing composite gel includes a solvent, and a plurality of swellable crosslinked polymer particles dispersed in a crosslinked polymer matrix, wherein the crosslinked polymer matrix and the plurality of swellable crosslinked polymer particles are immersed in the solvent, wherein the swellable crosslinked polymer particles absorb more solvent at equilibrium than the matrix polymer, and wherein the plurality of swellable crosslinked polymer particles swell in the solvent and are present in an amount sufficient to maintain or increase the elastic modulus and/or load-bearing ability of the self-reinforcing composite gel, i.e., compared to that of the crosslinked matrix polymer alone, upon swelling in the solvent. |
| FILED | Thursday, February 06, 2020 |
| APPL NO | 16/783494 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 47/32 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/48 (20130101) Original (OR) Class A61L 27/3817 (20130101) A61L 27/3834 (20130101) A61L 2430/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/24 (20130101) C08J 3/075 (20130101) C08J 2329/04 (20130101) C08J 2433/02 (20130101) Compositions of Macromolecular Compounds C08L 29/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083336 | Cruttenden et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Corey Edward Cruttenden (Minneapolis, Minnesota); Rajesh Rajamani (Saint Paul, Minnesota); Wei Chen (Plymouth, Minnesota); Xiao-Hong Zhu (Plymouth, Minnesota); Mahdi Ahmadi (Minneapolis, Minnesota) |
| ABSTRACT | A device includes a substrate, an electrode, an electrical pad, and a signal line. The signal line is coupled to the substrate and covered by an insulation layer. The signal line is coupled to the electrical pad and the electrode. At least one of the electrode and the signal line includes a diamagnetic material and paramagnetic material, wherein a ratio of the diamagnetic material and the paramagnetic material is selected based on the susceptibility properties of a physiological tissue. The term paramagnetic herein refers to magnetic susceptibility greater than that of the surrounding tissue and diamagnetic refers to magnetic susceptibility lower than that of the tissue. |
| FILED | Tuesday, August 16, 2022 |
| APPL NO | 17/820115 |
| ART UNIT | 3796 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 5/6868 (20130101) A61B 5/6877 (20130101) A61B 5/7207 (20130101) A61B 2562/125 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/086 (20170801) A61N 1/0534 (20130101) Original (OR) Class A61N 1/0551 (20130101) A61N 1/36003 (20130101) A61N 1/36053 (20130101) A61N 1/36062 (20170801) A61N 1/36067 (20130101) A61N 1/36103 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083339 | Ivey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia); Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia); Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| INVENTOR(S) | Jill W. Ivey (Blacksburg, Virginia); Eduardo L. Latouche (Blacksburg, Virginia); Scott S. Verbridge (Blacksburg, Virginia); Rafael V. Davalos (Blacksburg, Virginia); Glenn J. Lesser (Winston-Salem, North Carolina); Waldemar Debinski (Blacksburg, Virginia) |
| ABSTRACT | Described herein are methods of electroporation that can include the steps of contacting a cell that is responsive to an EphA2 receptor ligand with an amount of an EphA2 receptor ligand and applying high-frequency irreversible electroporation to the cell. Also described herein are methods of treating cancer in a subject in need thereof, wherein the methods can include the steps of administering an amount of an EphA2 receptor ligand and applying high-frequency irreversible electroporation to a location on or within the subject. |
| FILED | Friday, October 06, 2017 |
| APPL NO | 16/340106 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/12 (20130101) A61B 18/1233 (20130101) A61B 2017/00172 (20130101) A61B 2018/126 (20130101) A61B 2018/128 (20130101) A61B 2018/00613 (20130101) A61B 2018/00732 (20130101) A61B 2018/00767 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/19 (20130101) A61K 38/1793 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/06 (20130101) A61N 1/327 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083447 | Andrews et al. |
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| FUNDED BY |
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| APPLICANT(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical, Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Robert R. Andrews (Norfolk, Massachusetts); Herman E. Snyder (W. Lafayette, Indiana); William J. Merritt (Danvers, Massachusetts); Kyle D. Erickson (Melrose, Massachusetts); Evan P. Ordway (Salem, Massachusetts); Clair Strohl (Emmaus, Pennsylvania); Russell Barron (Boston, Massachusetts) |
| ABSTRACT | An alignment system that allows a spray drying disposable to align in both spray drying apparatus and finishing apparatus. The first instance is a locating arrangement wherein a locator is disposed on the spray drying apparatus and/or finishing apparatus and another locator is on the spray drying head of the disposable such that the locators allow for alignment of the disposable with the spray drying apparatus or finishing apparatus. A second instance of an alignment element includes a guide that is offset as positioned on the spray drying head of the disposable. Yet a third instance of the alignment arrangement relates to the gas exhaust port. In a fourth instance, the alignment system includes a positioning arrangement to reversibly attach the outer wall of the disposable to the finishing apparatus. In a fifth and sixth instance, a retaining device that retains the spray drying head in the spray drying apparatus and/or finishing apparatus. |
| FILED | Thursday, September 15, 2022 |
| APPL NO | 17/945130 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 1/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083448 | Jones et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Jennifer C. Jones (Bethesda, Maryland); Joshua A. Welsh (North Bethesda, Maryland); Katherine M. McKinnon (Germantown, Maryland); Jay A. Berzofsky (Bethesda, Maryland) |
| ABSTRACT | Disclosed is a method of purifying extracellular vesicles in a sample comprising extracellular vesicles and molecules that are not bound to the extracellular vesicles. The method includes (a) providing a mixed mode resin composition containing a first resin having pores with a pore size that traps unbound molecules by at least by a size exclusion mechanism, and a second resin containing at least one affinity ligand; (b) contacting the sample with the mixed mode resin composition to trap at least a portion of the unbound molecules; and (c) separating the sample from the mixed mode resin composition and obtaining a sample containing extracellular vesicles at a higher concentration than prior to step (b). Further disclosed is a method of labeling an extracellular vesicle with a fluorophore that labels proteins which includes the use of a mixed mode resin composition. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/959071 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/34 (20130101) Original (OR) Class B01D 15/3804 (20130101) B01D 15/3847 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/545 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083513 | Haghgooie et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Ramin Haghgooie (Arlington, Massachusetts); Robert Granier (Boston, Massachusetts); Kenneth T. Kotz (Auburndale, Massachusetts); Anne C. Petrofsky (Sudbury, Massachusetts) |
| ABSTRACT | An apparatus includes a device for storing a liquid sample, in which the device has a sample acceptance well, one or more storage chambers, and one or more fluidic channels fluidly coupling the sample acceptance well to the one or more storage chambers. The apparatus also includes a well plate having a plate and multiple wells formed in the plate, in which the device and the well plate are configured to be attached to one another. |
| FILED | Thursday, June 06, 2019 |
| APPL NO | 16/433432 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Original (OR) Class B01L 2200/10 (20130101) B01L 2200/16 (20130101) B01L 2200/027 (20130101) B01L 2200/028 (20130101) B01L 2200/0631 (20130101) B01L 2300/044 (20130101) B01L 2300/046 (20130101) B01L 2300/0672 (20130101) B01L 2300/0681 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0874 (20130101) B01L 2300/0887 (20130101) B01L 2400/0478 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083534 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | CIRCULOMICS INC. (Baltimore, Maryland) |
| ASSIGNEE(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| INVENTOR(S) | Kelvin Jeng-Fang Liu (Baltimore, Maryland); Jeffrey Michael Burke (Baltimore, Maryland) |
| ABSTRACT | Disclosed herein is a novel method to fabricate magnetic silica nanomembranes using thin polymer cores based on silica deposition and self-wrinkling induced by thermal shrinkage. These micro- and nano-scale structures have vastly enlarged the specific area of silica, thus the magnetic silica nanomembranes can be used for solid phase extraction of nucleic acids. The magnetic silica nanomembranes are suitable for nucleic acid purification and isolation and demonstrated better performance than commercial particles in terms of nucleic acid recovery yield and integrity. In addition, the magnetic silica nanomembranes may have high nucleic acid capacity due to significantly enlarged specific surface area of silica. Methods of use and devices comprising the magnetic silica nanomembranes are also provided herein. |
| FILED | Wednesday, November 03, 2021 |
| APPL NO | 17/518183 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/424 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/01 (20130101) B03C 1/30 (20130101) Original (OR) Class B03C 1/286 (20130101) B03C 1/288 (20130101) B03C 2201/18 (20130101) B03C 2201/26 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/12 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/06 (20130101) C08J 2323/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1013 (20130101) C12N 15/1017 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) G01N 35/0098 (20130101) G01N 35/0099 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084411 | Burke et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Martin D. Burke (Champaign, Illinois); Anthony S. Grillo (Champaign, Illinois); Alexander G. Cioffi (Urbana, Illinois); Anna SantaMaria (Rockville, Maryland); Daniel Blair (Hull, United Kingdom); Andrew Blake (Urbana, Illinois) |
| ABSTRACT | Disclosed are analogues of hinokitiol, methods for preparing them, and pharmaceutical compositions thereof. Also disclosed are methods for their use in treating iron-related diseases. |
| FILED | Friday, April 12, 2019 |
| APPL NO | 17/046608 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 45/68 (20130101) Original (OR) Class C07C 61/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084415 | Johnson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jeremiah A. Johnson (Boston, Massachusetts); Hung Vanthanh Nguyen (Braintree, Massachusetts); Peyton Shieh (Cambridge, Massachusetts); Wencong Wang (Cambridge, Massachusetts); Bin Liu (Hopkinton, Massachusetts); Valerie Lensch (Cambridge, Massachusetts); Landon Kilgallon (Cambridge, Massachusetts); Yutong Dai (Somerville, Massachusetts); Samantha Lynn Kristufek (Lubbock, Texas) |
| ABSTRACT | The present disclosure provides enynes, end-functionalized polymers, conjugates, methods of preparation, compositions, kits, and methods of use. The conjugates comprise at least (1) a peptide (e.g., an antibody), protein, nucleoprotein, mucoprotein, lipoprotein, glycoprotein, or polynucleotide; and (2) a polymer comprising a pharmaceutical agent. The conjugates may be useful in delivering (e.g., targeted delivering) the pharmaceutical agent to a subject in need thereof or cell or treating, preventing, or diagnosing a disease. |
| FILED | Thursday, October 20, 2022 |
| APPL NO | 17/970533 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/60 (20130101) C07C 301/02 (20130101) Heterocyclic Compounds C07D 207/277 (20130101) Original (OR) Class C07D 257/08 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/08 (20130101) C08G 2261/136 (20130101) C08G 2261/354 (20130101) C08G 2261/418 (20130101) C08G 2261/1424 (20130101) C08G 2261/1432 (20130101) C08G 2261/1646 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084418 | Khan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Clark Atlanta University, Inc. (Atlanta, Georgia); Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | CLARK ATLANTA UNIVERSITY, INC. (Atlanta, Georgia); GEORGIA TECH RESEARCH CORPORATION (Atlanta, Georgia) |
| INVENTOR(S) | Shafiq A. Khan (Mableton, Georgia); Silvia Caggia (Decatur, Georgia); Adegboyega K. Oyelere (Marietta, Georgia); Subhasish Tapadar (Atlanta, Georgia) |
| ABSTRACT | The disclosure relates to novel compounds and methods of use of the compounds to maintain the Gαi2 protein in its inactive GDP-bound state. The disclosure describes the knockdown or inhibition of Gαi2 negatively regulated migration of breast and ovarian cancer cell lines. The novel compounds inhibit the migratory behavior of PC3, DU145 and E006AA prostate cancer cell lines. Specifically, the novel compounds block the activation of Gαi2 in oxytocin-stimulated prostate cancer PC3 cells and inhibits the migratory capability of DU145 cells overexpressing constitutively active form of Gαi2, under basal and EGF-stimulated conditions. |
| FILED | Monday, December 20, 2021 |
| APPL NO | 17/556820 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 209/08 (20130101) C07D 209/36 (20130101) Original (OR) Class C07D 333/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084423 | Zheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | BioVentures, LLC (Little Rock, Arkansas) |
| ASSIGNEE(S) | BioVentures, LLC (Little Rock, Arkansas) |
| INVENTOR(S) | Guangrong Zheng (Little Rock, Arkansas); Daohong Zhou (Little Rock, Arkansas); Xuan Zhang (Little Rock, Arkansas) |
| ABSTRACT | The present disclosure provides compositions and methods for selectively killing senescent cells, wherein the composition comprises piperlongumine derivative thereof. The selective killing of senescent cells may delay aging and/or treat age-related disorders. |
| FILED | Friday, May 18, 2018 |
| APPL NO | 17/056705 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 211/88 (20130101) C07D 223/10 (20130101) Original (OR) Class C07D 265/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084437 | Kamenecka et al. |
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| FUNDED BY |
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| APPLICANT(S) | AstraZeneca AB (Södertälje, Sweden); EOLAS THERAPEUTICS, INC. (Carlsbad, California) |
| ASSIGNEE(S) | ASTRAZENECA AB (Södertälje, Sweden); EOLAS THERAPEUTICS, INC (Carlsbad, California) |
| INVENTOR(S) | Theodore M. Kamenecka (Palm Beach Gardens, Florida); Jörg Holenz (Bolton, Massachusetts); Steven Wesolowski (Natick, Massachusetts); Yuanjun He (Palm Beach Gardens, Florida); Roland Bürli (Hertfordshire, United Kingdom) |
| ABSTRACT | The present application relates to certain halo-substituted piperidine compounds, pharmaceutical compositions containing them, and methods of using them, including methods for treating substance addiction, panic disorder, anxiety, post-traumatic stress disorder, pain, depression, seasonal affective disorder, an eating disorder, or hypertension. |
| FILED | Wednesday, July 20, 2022 |
| APPL NO | 17/868856 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/34 (20180101) Heterocyclic Compounds C07D 401/14 (20130101) C07D 409/14 (20130101) C07D 413/14 (20130101) C07D 417/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
12084451 — Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
| US 12084451 | Ginty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David D. Ginty (Cambridge, Massachusetts); Lauren L. Orefice (Cambridge, Massachusetts); Jinbo Lee (Cambridge, Massachusetts) |
| ABSTRACT | The present invention features novel peripherally-restricted non-benzodiazipene analogs with reduced blood brain barrier permeability and methods of use thereof for reducing tactile dysfunction, social impairment, and anxiety in a subject diagnosed with Autism Spectrum Disorder, Rett syndrome, Phelan McDermid syndrome, or Fragile X syndrome, or for treating touch over-reactivity, pain, or mechanical allodynia. |
| FILED | Wednesday, August 24, 2022 |
| APPL NO | 17/894864 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/04 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084456 | Sarlah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University Of Illinois (Urbana, Illinois) |
| INVENTOR(S) | David Sarlah (Champaign, Illinois); Tanner W. Bingham (Urbana, Illinois); Lucas William Hernandez (Urbana, Illinois) |
| ABSTRACT | Enantioselective total syntheses of the anticancer isocarbostyril alkaloids (+)-7-deoxypancratistatin, (+)-pancratistatin, (+)-lycoricidine, and (+)-narciclasine are described. Our strategy for accessing this unique class of natural products is based on the development of a Ni-catalyzed dearomative trans-1,2-carboamination of benzene. The effectiveness of this dearomatization approach is notable, as only two additional olefin functionalizations are needed to construct the fully decorated aminocyclitol cores of these alkaloids. Installation of the lactam ring has been achieved through several pathways and a direct interconversion between natural products was established via a late-stage C-7 cupration. Using this synthetic blueprint, we were able to produce natural products on a gram scale and provide tailored analogs with improved activity, solubility, and metabolic stability. |
| FILED | Wednesday, December 04, 2019 |
| APPL NO | 17/299365 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/22 (20130101) B01J 2531/16 (20130101) Heterocyclic Compounds C07D 491/056 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084480 | Chilkoti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Ashutosh Chilkoti (Durham, North Carolina); Nicholas Tang (Durham, North Carolina); Garrett Kelly (Durham, North Carolina) |
| ABSTRACT | Described herein are unstructured polypeptides lacking any discernible repeat motif. Also described herein are fusion proteins including at least one of the unstructured polypeptides and at least one binding polypeptide. Further described are methods for treating a disease in a subject in need thereof. The methods may include administering to the subject an effective amount of the fusion protein. |
| FILED | Thursday, September 16, 2021 |
| APPL NO | 17/477192 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 47/65 (20170801) Peptides C07K 14/31 (20130101) Original (OR) Class C07K 2319/02 (20130101) C07K 2319/21 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084481 | Goldstein |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Steven Alan Goldstein (Chicago, Illinois) |
| ABSTRACT | The present invention provides novel agents for modulation of Hv1 channels. The present invention provides agents for activating and/or inhibiting Hv1 channel function and/or activity, and reagents and methods relating thereto. |
| FILED | Tuesday, March 01, 2022 |
| APPL NO | 17/684346 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/705 (20130101) C07K 14/43518 (20130101) Original (OR) Class C07K 14/43522 (20130101) C07K 2319/02 (20130101) C07K 2319/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084483 | Malek |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | University of Miami (Miami, Florida) |
| INVENTOR(S) | Thomas Malek (Miami Beach, Florida) |
| ABSTRACT | Various methods and compositions are provided which can be employed to modulate the immune system. Compositions include a fusion protein comprising: (a) a first polypeptide comprising Interleukin-2 (IL-2) or a functional variant or fragment thereof; and (b) a second polypeptide, fused in frame to the first polypeptide, wherein the second polypeptide comprises an extracellular domain of Interleukin-2 Receptor alpha (IL-2Rα) or a functional variant or fragment thereof, and wherein the fusion protein has IL-2 activity. Various methods are provided for modulating the immune response in a subject comprising administering to a subject in need thereof a therapeutically effective amount of the IL-2/IL-2Rα fusion protein disclosed herein. |
| FILED | Wednesday, August 05, 2015 |
| APPL NO | 15/501392 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/55 (20130101) Original (OR) Class C07K 14/7155 (20130101) C07K 2319/00 (20130101) C07K 2319/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084487 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Lily Yang (Atlanta, Georgia); Erica Bozeman (North Wales, Pennsylvania) |
| ABSTRACT | This disclosure relates to peptides and nanoparticles comprising a surface molecule that binds or blocks PD-L1. In certain embodiments, the disclosure relates to methods of using peptides or nanoparticles disclosed herein for the treatment of cancer. In certain embodiments, the disclosure relates to methods of using nanoparticles disclosed herein for therapeutic and diagnostic applications. |
| FILED | Monday, July 24, 2023 |
| APPL NO | 18/357979 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/405 (20130101) A61K 31/405 (20130101) A61K 31/4245 (20130101) A61K 31/4245 (20130101) A61K 31/7088 (20130101) A61K 38/177 (20130101) A61K 38/482 (20130101) A61K 38/4886 (20130101) A61K 45/06 (20130101) A61K 47/62 (20170801) A61K 47/6929 (20170801) A61K 47/6939 (20170801) A61K 49/0002 (20130101) A61K 49/0093 (20130101) A61K 49/1866 (20130101) A61K 51/08 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 14/70521 (20130101) Original (OR) Class C07K 14/70596 (20130101) C07K 2319/21 (20130101) Enzymes C12Y 304/2408 (20130101) C12Y 304/21073 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084489 | Kanekiyo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Masaru Kanekiyo (North Bethesda, Maryland); Michael Gordon Joyce (Washington, District of Columbia); Wei Bu (Potomac, Maryland); Jeffrey I. Cohen (Silver Spring, Maryland); Yaroslav Tsybovsky (Brunswick, Maryland) |
| ABSTRACT | Anti-EBV gH antibodies, anti-EBV gL antibodies, anti-EBV gH/gL antibodies, and compositions of matter useful for the detection, diagnosis, prevention, and treatment of Epstein Barr Virus infection in humans, and methods of using those compositions of matter for the same. |
| FILED | Thursday, May 02, 2019 |
| APPL NO | 17/052470 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6803 (20170801) A61K 47/6839 (20170801) Peptides C07K 16/085 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/55 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/705 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56994 (20130101) G01N 2333/05 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084490 | Sierks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Michael Sierks (Ft. McDowell, Arizona); Huilai Tian (Tempe, Arizona) |
| ABSTRACT | The invention relates to antibodies, antibody fragments and binding agents that specifically recognize oligomeric tau but do not bind to monomeric tau, fibrillar tau or non-disease associated forms of tau. |
| FILED | Friday, May 21, 2021 |
| APPL NO | 17/327462 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/005 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/30 (20130101) C07K 2317/62 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) G01N 2333/47 (20130101) G01N 2333/4703 (20130101) G01N 2800/28 (20130101) G01N 2800/2814 (20130101) G01N 2800/2821 (20130101) G01N 2800/7047 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084493 | Bose et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | Washington State University (Pullman, Washington) |
| INVENTOR(S) | Santanu Bose (Pullman, Washington); Philippe Tessier (Quebec, Canada) |
| ABSTRACT | The present disclosure provides methods of treating a pathogen-induced lung inflammation in a subject are provided in which an anti-S100A9 antibody is administered to a subject. Methods of treating a respiratory virus infection by administering an anti-S100A9 antibody are also provided. |
| FILED | Monday, August 17, 2020 |
| APPL NO | 16/994882 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/24 (20130101) Original (OR) Class C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084508 | Badley |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Andrew D. Badley (Rochester, Minnesota) |
| ABSTRACT | This document provides antibodies against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) short, and more particularly to humanized TRAILshort antibodies that can neutralize TRAILshort. For example, materials and methods for using one or more humanized TRAILshort antibodies to induce apoptosis (e.g., via TRAIL mediated cell death, natural killer (NK) cytotoxicity, and/or CD8+ T cell killing) are provided. |
| FILED | Tuesday, August 24, 2021 |
| APPL NO | 17/410832 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/191 (20130101) A61K 39/39558 (20130101) Peptides C07K 16/2875 (20130101) Original (OR) Class C07K 16/2878 (20130101) C07K 2317/24 (20130101) C07K 2317/73 (20130101) C07K 2317/75 (20130101) C07K 2317/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084517 | Spiegel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); Ryan Murelli (Belleville, New Jersey); Andrew Zhang (Waltham, Massachusetts) |
| ABSTRACT | The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule. |
| FILED | Wednesday, June 07, 2023 |
| APPL NO | 18/206937 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/4192 (20130101) A61K 45/06 (20130101) A61K 47/54 (20170801) A61K 47/55 (20170801) A61K 47/68 (20170801) A61K 47/549 (20170801) A61K 47/646 (20170801) A61K 47/6803 (20170801) A61K 47/6869 (20170801) A61K 47/6873 (20170801) A61K 47/6891 (20170801) Heterocyclic Compounds C07D 249/04 (20130101) Peptides C07K 16/44 (20130101) Original (OR) Class C07K 16/3069 (20130101) C07K 2317/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084519 | Shoemaker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Charles B. Shoemaker (Medford, Massachusetts); Hanping Feng (Medford, Massachusetts) |
| ABSTRACT | Methods, compositions and kits are provided for treating a subject exposed to or at risk for exposure to a disease agent using a pharmaceutical composition including at least one recombinant heteromultimeric neutralizing binding protein including two or multiple binding regions, such that the binding regions are not identical, and each binding region specifically binds a non-overlapping portion of the disease agent, thereby treating the subject for exposure to the disease agent. In a related embodiment, the heteromultimeric neutralizing binding protein includes two or multiple binding regions that neutralize a plurality of disease agents. In certain embodiments, the disease agent includes a bacterium, a bacterial protein, a virus, a viral protein, a cancer cell, and a protein or molecule produced therefrom. In certain embodiments, the disease agent is a plurality of different disease agents. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/371762 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) A61K 39/39591 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/40 (20130101) C07K 16/44 (20130101) C07K 16/468 (20130101) Original (OR) Class C07K 16/1282 (20130101) C07K 2317/31 (20130101) C07K 2317/62 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/569 (20130101) C07K 2317/622 (20130101) C07K 2319/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084521 | Toshchakov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University Of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | University Of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Vladimir Toshchakov (Owings Mills, Maryland); Artur Javmen (Baltimore, Maryland) |
| ABSTRACT | This invention relates generally to the field of medicine, and particularly to a TLR-9-specific inhibitor peptide effective in vitro and in vivo for modification of inflammatory signaling and host defense pathways. This peptide can be used for TLR-targeting pharmaceutics for treating inflammatory responses caused by various pathogenic and infectious diseases. The invention comprises peptides, peptide fusions, pharmaceutical compositions, and methods for using these compounds and compositions. Peptides of the invention include, but are not limited to SEQ ID NOs:4, 6, 8, 10, 12, 21, or 24, optionally fused to a cell-permeating moiety. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/967595 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class C07K 14/705 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084653 | Nakai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Hiroyuki Nakai (Portland, Oregon); Samuel Huang (Portland, Oregon); Kei Adachi (Portland, Oregon) |
| ABSTRACT | Disclosed are methods for performing transcription-dependent directed evolution (TRADE) and novel AAV capsids selected using such methods. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/160796 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/1082 (20130101) C12N 2310/11 (20130101) C12N 2320/33 (20130101) C12N 2750/14122 (20130101) C12N 2750/14123 (20130101) C12N 2750/14142 (20130101) C12N 2750/14145 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084654 | Nakai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Hiroyuki Nakai (Portland, Oregon); Samuel Huang (Portland, Oregon); Kei Adachi (Portland, Oregon) |
| ABSTRACT | Disclosed are methods for performing transcription-dependent directed evolution (TRADE) and novel AAV capsids selected using such methods. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/160804 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/11 (20130101) Original (OR) Class C12N 15/86 (20130101) C12N 15/1082 (20130101) C12N 2310/11 (20130101) C12N 2320/33 (20130101) C12N 2750/14122 (20130101) C12N 2750/14123 (20130101) C12N 2750/14142 (20130101) C12N 2750/14145 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084663 | Maianti et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Juan Pablo Maianti (Cambridge, Massachusetts); David R. Liu (Cambridge, Massachusetts); Luke W. Koblan (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are systems, compositions, and methods for the incorporation of unnatural amino acids into proteins via nonsense suppression or rare codon suppression. Nonsense codons and rare codons may be introduced into the coding sequence of a protein of interest using a CRISPR/Cas9-based nucleobase editor described herein. The nucleobase editors are able to be programmed by guide nucleotide sequences to edit the target codons in the coding sequence of the protein of interest. Also provided are application enabled by the technology described herein. |
| FILED | Monday, November 14, 2022 |
| APPL NO | 18/055274 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/78 (20130101) C12N 15/67 (20130101) Original (OR) Class C12N 15/102 (20130101) Enzymes C12Y 305/04001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084666 | Zanders et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STOWERS INSTITUTE FOR MEDICAL RESEARCH (Kansas City, Kansas); FRED HUTCHINSON CANCER CENTER (Seattle, Washington) |
| ASSIGNEE(S) | STOWERS INSTITUTE FOR MEDICAL RESEARCH (Kansas City, Missouri); FRED HUTCHINSON CANCER CENTER (Seattle, Washington) |
| INVENTOR(S) | Sarah E. Zanders (Prairie Village, Kansas); Nicole Nuckolls (Shawnee, Kansas); Maria Angelical Bravo Nunez (Kansas City, Kansas); Harmit Singh Malik (Shoreline, Washington) |
| ABSTRACT | The present disclosure provides, inter alia, meiotic drive genes derived from chromosome 3 of the fission yeasts Schizosaccharomyces kambucha and S. pombe and orthologs thereof. In certain embodiments, compositions, methods, and kits are provided for biasing organisms to express such genes and, optionally, to co-express one or more genes of interest in such organisms. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 16/608146 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/39 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/00 (20130101) C12N 15/815 (20130101) Original (OR) Class C12N 2800/00 (20130101) C12N 2840/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084674 | Saffarian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| INVENTOR(S) | Saveez Saffarian (Salt Lake City, Utah); Mourad Bendjennat (Salt Lake City, Utah) |
| ABSTRACT | Disclosed are nucleic acid sequences comprising a modified HIV Gag sequence, wherein the modified HIV Gag sequence comprises, from 5′ to 3′, a matrix domain (MA), capsid (CA) domain, SP1 region, nucleocapsid (NC) domain, SP2 region, and p6 domain, wherein the modified HIV Gag sequence further comprises an exogenous sequence of interest between the NC domain and the SP2 region. Disclosed are methods of producing a recombinant lentivirus comprising transfecting a cell with a plasmid comprising the nucleic acid sequence of one or more of the disclosed nucleic acid sequences in combination with an envelope plasmid. Disclosed are methods of monitoring lentivirus assembly, budding, and/or maturation comprising transfecting a cell with a plasmid comprising any one of the disclosed nucleic acid sequences in combination with an envelope plasmid, wherein the exogenous sequence of interest encodes a detection agent. Disclosed are methods of treating a subject with a therapeutic agent comprising administering to a subject in need thereof a recombinant lentivirus, wherein the recombinant lentivirus comprises one or more of the disclosed nucleic acid sequences, wherein the exogenous sequence of interest encodes a therapeutic agent. |
| FILED | Wednesday, October 07, 2020 |
| APPL NO | 17/065101 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2740/16022 (20130101) C12N 2740/16111 (20130101) C12N 2740/16222 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/703 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084677 | Taylor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Doris Taylor (St. Paul, Minnesota); Stefan M. Kren (Minneapolis, Minnesota) |
| ABSTRACT | Described herein are methods of recellularizing an organ or tissue matrix. |
| FILED | Wednesday, July 06, 2022 |
| APPL NO | 17/858960 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/3604 (20130101) A61L 27/3808 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084680 | Lippmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ethan Scott Lippmann (Nashville, Tennessee); Neha Sehgal (Philadelphia, Pennsylvania); Randolph Scott Ashton (Madison, Wisconsin) |
| ABSTRACT | Described herein are chemically defined, adherent culture protocols for generating functional motor neurons characteristic of diverse hindbrain and spinal cord regions, with high efficiency. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/149713 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0623 (20130101) Original (OR) Class C12N 2500/38 (20130101) C12N 2501/119 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2501/999 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084685 | Griffith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSAACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Linda G. Griffith (Cambridge, Massachusetts); Victor Hernandez-Gordillo (Cambridge, Massachusetts) |
| ABSTRACT | Synthetic hydrogels for organogenesis support organogenesis from mammalian cells, including human cells. The synthetic hydrogels typically include a network of crosslinked branched biodegradable polymers. A portion of the branches of the branched biodegradable polymers are linked to binders which are generally synthetic peptides for cell and extracellular matrix attachment. The hydrogels may include an inhibitor of apoptosis. The synthetic hydrogels with the synthetic binders typically do not interfere with cellular, proteomic, genetic, and/or transcriptome analyses of organoids formed in the hydrogel. The synthetic hydrogels may be subject to on-demand dissolution to provide intact organoids substantially free of hydrogel polymers. Also provided are methods of making the synthetic hydrogels and methods of using the synthetic hydrogels for organogenesis. |
| FILED | Wednesday, July 29, 2020 |
| APPL NO | 16/942580 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0679 (20130101) C12N 5/0682 (20130101) Original (OR) Class C12N 2533/40 (20130101) C12N 2533/50 (20130101) C12N 2533/52 (20130101) C12N 2533/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084689 | Korman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INVIZYNE TECHNOLOGIES, INC. (Monrovia, California) |
| ASSIGNEE(S) | INVIZYNE TECHNOLOGIES, INC. (Monrovia, California) |
| INVENTOR(S) | Tyler P. Korman (Sierra Madre, California) |
| ABSTRACT | The present disclosure relates to recombinant prenyltransferase enzymes with increased thermostability and activity and the use of these enzymes in compositions and methods for biosynthesis involving prenylation reactions, including compositions and methods for the preparation of cannabinoids. |
| FILED | Thursday, September 22, 2022 |
| APPL NO | 17/934560 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1085 (20130101) Original (OR) Class C12N 15/52 (20130101) C12N 15/8243 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) Enzymes C12Y 203/01206 (20150701) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084695 | Veress et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NATIONAL JEWISH HEALTH (Denver, Colorado) |
| ASSIGNEE(S) | National Jewish Health (Denver, Colorado) |
| INVENTOR(S) | Livia A. Veress (Denver, Colorado); Carl W. White (Denver, Colorado) |
| ABSTRACT | The present invention is directed to methods of treatment of airway obstruction associated with fibrin-containing cast formation by administering a fibrinolytic agent. |
| FILED | Monday, December 06, 2021 |
| APPL NO | 17/543407 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0078 (20130101) A61K 38/49 (20130101) A61K 38/482 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6459 (20130101) Original (OR) Class C12N 9/6462 (20130101) Enzymes C12Y 304/21068 (20130101) C12Y 304/21073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084696 | Colecraft et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Henry M. Colecraft (Robbinsville, New Jersey); Scott Kanner (New York, New York) |
| ABSTRACT | The present disclosure provides, inter alia, a recombinant engineered deubiquitinase (DUB) and methods for treating or ameliorating an inherited ion channelopathy, such as long QT syndrome, Brugada syndrome, or cystic fibrosis, in a subject. Further provided are methods for screening mutations causing such inherited ion channelopathies for a trafficking-deficient mutation that is treatable by the recombinant engineered DUB disclosed herein. |
| FILED | Friday, November 03, 2023 |
| APPL NO | 18/501966 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6472 (20130101) Original (OR) Class C12N 15/85 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 304/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084713 | Stengel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alida Biosciences Inc. (San Diego, California) |
| ASSIGNEE(S) | Alida Biosciences Inc. (San Diego, California) |
| INVENTOR(S) | Gudrun Stengel (San Diego, California); Byron Purse (San Diego, California); Yu-Hsien Hwang-Fu (San Diego, California); Jerome Santos (San Diego, California) |
| ABSTRACT | Provided herein are compositions and methods for the multiplexed profiling of RNA and DNA modifications across transcriptomes and genomes, respectively. The methods combine molecular recognition of non-canonical features (e.g., base modifications, backbone modifications, lesions, and/or structural elements) of a target nucleic acid with a step of writing the information from this recognition event into the neighboring genetic sequence of the target nucleic acid using a barcode. The resultant barcoded nucleic acids are then converted into sequencing libraries and read by DNA/RNA sequencing methods. This step reveals the sequence of the barcode, which is correlated with the non-canonical feature in the target nucleic acid(s). The high throughput profiling methods described herein allow for localization of one or more modifications in a target nucleic acid. The methods also allow for identification of the nature and location of several or all DNA/RNA modifications in parallel. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/706470 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084722 | Rotter et al. |
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| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Jerome I. Rotter (Los Angeles, California); Marla Dubinsky (Los Angeles, California); Stephan R. Targan (Santa Monica, California); Kent D. Taylor (Ventura, California) |
| ABSTRACT | The present invention relates to methods of prognosing responsiveness to anti-TNFα therapy by determining the presence or absence of risk factors in the individual. In one embodiment, the risk factors are genetic markers, serological markers and/or clinical phenotypes associated with non-responsiveness to treatment with anti-TNFα therapy in an individual diagnosed with IBD. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/551028 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085533 | Gundlach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Jens H. Gundlach (Seattle, Washington); Ian Michael Derrington (Seattle, Washington); Andrew Laszlo (Seattle, Washington); Jonathan Craig (Seattle, Washington); Henry Brinkerhoff (Seattle, Washington) |
| ABSTRACT | Methods for nanopore-based protein analysis are provided. The methods address the characterization of a target protein analyte, which has a dimension greater than an internal diameter of the nanopore tunnel, and which is also physically associated with a polymer. The methods further comprise applying an electrical potential to the nanopore system to cause the polymer to interact with the nanopore tunnel. The ion current through the nanopore is measured to provide a current pattern reflective of the structure of the portion of the polymer interacting with the nanopore tunnel. This is used as a metric for characterizing the associated protein that does not pass through the nanopore. |
| FILED | Wednesday, September 27, 2023 |
| APPL NO | 18/475534 |
| ART UNIT | 1759 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44743 (20130101) Original (OR) Class G01N 27/44791 (20130101) G01N 33/6818 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085534 | Xu et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Shoujun Xu (Houston, Texas); Yuhong Wang (Houston, Texas); Haina Jia (Houston, Texas); Heng Yin (Houston, Texas); Yujia Mao (Houston, Texas) |
| ABSTRACT | A method of measuring dissociation of the biomolecular bonds in one or multiple sample wells using super-resolution force spectroscopy (SURFS). SURFS utilizes precise ultrasound radiation to exert an acoustic radiation force on the biomolecular bonds labeled with magnetic particles. The force-induced dissociation of the protein bonds labeled with magnetic particles may be measured as a reduced magnetic signal by a magnetic sensor. The force resolution allows for differentiating biomolecular bonds with an extremely high level of precision. The biomolecular bonds include protein-protein, protein-nucleic acid, nucleic acid-nucleic acid, small molecule-protein, and small molecule-nucleic acid interactions. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/968535 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0207 (20130101) B06B 1/0622 (20130101) B06B 1/0651 (20130101) B06B 2201/77 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/72 (20130101) Original (OR) Class G01N 33/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085552 | Haley et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Michael M. Haley (Eugene, Oregon); Michael Pluth (Eugene, Oregon); Darren W. Johnson (Eugene, Oregon); Sean Fontenot (Eugene, Oregon) |
| ABSTRACT | A device that includes a polymeric layer, wherein the polymeric layer comprises (A) a polymer and, incorporated within the polymeric layer, (B) a compound, or a protonate or salt thereof, wherein the compound, or a protonate or salt thereof, has a structure that includes at least one moiety configured for reversible, non-covalent binding of the anionic sulfide species. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/536994 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 275/28 (20130101) C07C 275/34 (20130101) Heterocyclic Compounds C07D 213/40 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/414 (20130101) G01N 33/182 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/184 (20150115) Y10T 436/156666 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085565 | Siman |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Robert Siman (Wilmington, Delaware) |
| ABSTRACT | The invention relates to methods for providing prognosis, diagnosis, monitoring and treatment of a mild traumatic brain injury (mTBI) in a subject, including a sports-related concussion. The invention further relates to assessing the severity of brain damage resulting from mTBI in a subject, including in a subject who has not undergone a CT scan following the injury. For example, the methods of the invention can be used to determine the suitability for someone who has suffered a sports-related injury to return to play that sport. This invention also relates to methods of predicting risk for developing brain damage and long-term dysfunction in a subject having suffered mTBI. |
| FILED | Friday, March 23, 2018 |
| APPL NO | 15/934837 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/566 (20130101) Original (OR) Class G01N 33/6896 (20130101) G01N 2333/47 (20130101) G01N 2333/4703 (20130101) G01N 2800/28 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/2871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085569 | LaBaer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Joshua LaBaer (Chandler, Arizona); Jie Wang (Glendale, Arizona); Ji Qiu (Chandler, Arizona); Garrick Wallstrom (Mesa, Arizona); Karen Anderson (Scottsdale, Arizona); Jin Park (Phoenix, Arizona); Jonine Figueroa (Edinburgh, United Kingdom) |
| ABSTRACT | Cancer patients make antibodies to tumor-derived proteins that are potential biomarkers for early detection. Twenty-eight antigens have been identified as potential biomarkers for the early detection of basal-like breast cancer (Tables 1, 2). Also, a 13-AAb classifier has been developed that differentiate patients with BLBC from healthy controls with 33% sensitivity at 98% specificity (Table 3). |
| FILED | Thursday, September 08, 2022 |
| APPL NO | 17/940883 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/3015 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/57415 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085572 | Gunther et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Erik Gunther (Branford, Connecticut); Mikhail Kostylev (New Haven, Connecticut); Stephen Strittmatter (Durham, Connecticut) |
| ABSTRACT | In one aspect, the invention provides a protein capture membrane comprising a first side and a second side and a plurality of interstices extending contiguously from the first side to the second side, wherein the interstices are coated with a protein-reactive coating; and the porous substrate comprises nanoporous alumina or porous glass. In another aspect the invention provides a method of detecting a protein of interest in a plurality of proteins. |
| FILED | Tuesday, May 07, 2019 |
| APPL NO | 17/053023 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 57/02 (20130101) B01D 69/02 (20130101) B01D 69/108 (20220801) B01D 2325/04 (20130101) B01D 2325/0283 (20220801) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6842 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085575 | Desai |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana) |
| INVENTOR(S) | Shyamal D. Desai (Metairie, Louisiana) |
| ABSTRACT | This invention is directed to compositions and methods for detecting proteinopathies. |
| FILED | Monday, March 29, 2021 |
| APPL NO | 17/215980 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/52 (20130101) A61K 31/713 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2333/56 (20130101) G01N 2500/00 (20130101) G01N 2800/52 (20130101) G01N 2800/2835 (20130101) G01N 2800/7047 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 67/1001 (20220501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085629 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Xin Zhang (Medford, Massachusetts); Stephan Anderson (Cambridge, Massachusetts); Xiaoguang Zhao (Charlestown, Massachusetts); Guangwu Duan (Cupertino, California) |
| ABSTRACT | A passive MRI enhancing embodiment includes a plurality of resonators and increases signal-to-noise ratio of radiofrequency signals emitted by a specimen and captured by an MRI machine. The apparatus increases the magnetic field component of radiofrequency energy during signal transmission from the MRI machine to the specimen, and/or reception of signals from the specimen to the MRI machine. Use of the apparatus improves the images generated by the MRI machine, and/or reduces the time necessary for the MRI machine to capture the image. An isolator embodiment has a nonlinear resonator controllably configurable alternately into an isolation configuration and a transmission configuration, and a second resonator. The nonlinear resonator is coupled to a communications port and is substantially communicatively isolated from the second resonator when the nonlinear resonator is in the isolation configuration, and is communicatively coupled to the second resonator when the nonlinear resonator is in the transmission configuration. |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 17/545538 |
| ART UNIT | 3798 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/12 (20130101) G01R 33/3415 (20130101) Original (OR) Class G01R 33/34038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085631 | Trzasko et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | May Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Joshua D. Trzasko (Rochester, Minnesota); Matthew A. Bernstein (Rochester, Minnesota); Uten Yarach (Rochester, Minnesota) |
| ABSTRACT | Images are reconstructed from k-space data using a model-based image reconstruction that prospectively and simultaneously accounts for multiple non-idealities in accelerated single-shot-EPI acquisitions. In some implementations, nonlinear regularization (e.g., sparsity regularization) is also incorporated to mitigate noise amplification. The reconstructed images have reduced distortions and noise amplification effects relative to those images that are processed using conventional post-reconstruction techniques to correct for non-idealities. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 17/606645 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4818 (20130101) G01R 33/5608 (20130101) G01R 33/5616 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087566 | Eberlin et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Livia Schiavinato Eberlin (Austin, Texas); Thomas Milner (Austin, Texas); Jialing Zhang (Austin, Texas); John Lin (Lin, Texas); John Rector (Austin, Texas); Nitesh Katta (Austin, Texas); Aydin Zahedivash (Austin, Texas) |
| ABSTRACT | Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis. |
| FILED | Friday, July 28, 2023 |
| APPL NO | 18/227417 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/0045 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0293 (20130101) B01L 3/502 (20130101) B01L 2200/0605 (20130101) B01L 2400/0655 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) G01N 30/72 (20130101) G01N 33/487 (20130101) G01N 33/574 (20130101) G01N 33/6848 (20130101) G01N 2001/028 (20130101) G01N 2001/4061 (20130101) G01N 2560/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/04 (20130101) H01J 49/0031 (20130101) H01J 49/0431 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12083162 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Liangfang Zhang (San Diego, California); Weiwei Gao (La Jolla, California); Ronnie H. Fang (San Diego, California) |
| ABSTRACT | A nanoparticle comprising an outer surface comprising a plasma membrane derived from a cell that can be infected with a respiratory virus, including a human lung epithelial cell expressing ACE-2 receptor. Methods of manufacture and use for preventing or treating viral infections, such as coronavirus infection in a subject in need are disclosed. |
| FILED | Monday, March 22, 2021 |
| APPL NO | 17/208228 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 38/1796 (20130101) Original (OR) Class A61K 47/6901 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083172 | Lyerly et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Herbert K. Lyerly (Durham, North Carolina); Takuya Osada (Durham, North Carolina); Zachary C. Hartman (Durham, North Carolina) |
| ABSTRACT | Methods of reducing the likelihood of a cancer or precancer developing resistance to a cancer therapeutic or prevention agent are provided herein. The methods include administering a vaccine comprising a polynucleotide encoding a polypeptide whose expression or activation is correlated with development of resistance of the cancer or precancer to the cancer therapeutic or prevention agent to a subject. The vaccine may include a polynucleotide encoding a HER2 polypeptide or a truncation, deletion or substitution mutant thereof. Methods of using the vaccine including the polynucleotide encoding the HER2 polypeptide to treat a cancer or precancer are also provided. The vaccines may be administered with a cancer therapeutic or prevention agent or a checkpoint inhibitor immunomodulatory agent. |
| FILED | Thursday, November 19, 2020 |
| APPL NO | 16/953221 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/45 (20130101) A61K 39/0011 (20130101) A61K 39/001102 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) Original (OR) Class A61K 39/3955 (20130101) A61K 2039/53 (20130101) A61K 2300/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 16/2818 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/15034 (20130101) C12N 2740/15043 (20130101) Enzymes C12Y 207/10001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083174 | Bertholet Girardin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
| ASSIGNEE(S) | GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
| INVENTOR(S) | Sylvie Bertholet Girardin (Rockville, Maryland); Arun Kumar (Siena, Italy) |
| ABSTRACT | The present invention is in the field of treating and/or preventing viral infections. In particular, the present invention relates to immunogenic or pharmaceutical compositions comprising self-replicating RNA molecules that encode influenzavirus antigens for treating and/or preventing influenza infections. |
| FILED | Friday, August 16, 2019 |
| APPL NO | 17/268647 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/70 (20130101) A61K 2039/55555 (20130101) A61K 2039/55566 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083181 | Spiegel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | David Spiegel (New Haven, Connecticut); David Caianiello (New Haven, Connecticut) |
| ABSTRACT | Described herein is a bi-functional compound for removing macrophage migration inhibitory factor (MIF) or immunoglobulin G (IgG). Further described herein is a pharmaceutical composition which comprise these bi-functional compounds. Further described herein is a method for treating disease states and/or conditions with the compounds or the composition. The disease states and/or conditions are mediated through MIF/IgG or where MIF/IgG is a contributing factor to the development and perpetuation of diseases and/or conditions, such as autoimmune diseases and cancer, among others. |
| FILED | Monday, January 30, 2023 |
| APPL NO | 18/161633 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/55 (20170801) Original (OR) Class A61K 47/545 (20170801) A61K 47/549 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083448 | Jones et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Jennifer C. Jones (Bethesda, Maryland); Joshua A. Welsh (North Bethesda, Maryland); Katherine M. McKinnon (Germantown, Maryland); Jay A. Berzofsky (Bethesda, Maryland) |
| ABSTRACT | Disclosed is a method of purifying extracellular vesicles in a sample comprising extracellular vesicles and molecules that are not bound to the extracellular vesicles. The method includes (a) providing a mixed mode resin composition containing a first resin having pores with a pore size that traps unbound molecules by at least by a size exclusion mechanism, and a second resin containing at least one affinity ligand; (b) contacting the sample with the mixed mode resin composition to trap at least a portion of the unbound molecules; and (c) separating the sample from the mixed mode resin composition and obtaining a sample containing extracellular vesicles at a higher concentration than prior to step (b). Further disclosed is a method of labeling an extracellular vesicle with a fluorophore that labels proteins which includes the use of a mixed mode resin composition. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/959071 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/34 (20130101) Original (OR) Class B01D 15/3804 (20130101) B01D 15/3847 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/545 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083466 | Roth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | USA as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Marc L. Roth (Owens Cross Roads, Alabama); William J Spangler, Jr. (Forest Hill, Michigan); Lester D Strauch, III (Churchville, Maryland); Patrick O Hulbert (Dallastown, Pennsylvania); Robert Michael Ferguson (Baytown, Texas) |
| ABSTRACT | The present disclosure provides a filter cartridge for a facepiece respirator mask body. The filter cartridge includes a cover, a base, and a filter medium. The cover has a top surface, a cover sidewall, cover support elements, and an inhalation vent. The cover support elements extend downwardly from the top surface. The inhalation vent is located at least primarily in the cover sidewall. The base has a bottom surface, a base sidewall, base support elements, and an inhalation port. The base support elements extend upwardly from the bottom surface. The inhalation port is located in the bottom surface. The base and the cover collectively define an interior compartment. The filter medium is sandwiched between the base support elements and the cover support elements in a manner that divides the interior compartment into an upper chamber and a lower chamber. |
| FILED | Thursday, April 22, 2021 |
| APPL NO | 17/237247 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 19/00 (20130101) A62B 23/02 (20130101) Separation B01D 46/0004 (20130101) B01D 46/0005 (20130101) B01D 46/10 (20130101) B01D 46/0045 (20130101) Original (OR) Class B01D 2265/028 (20130101) B01D 2279/65 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083504 | Christopher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of The University Of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Phillip Christopher (Santa Barbara, California); Ji Qi (Santa Barbara, California) |
| ABSTRACT | Catalysts containing a support and a metal oxide, and reactors and methods of using the catalysts in a carbonylation reaction, such as alcohol carbonylation and ester carbonylation, are described herein. The support is typically chemically inert and has a high surface area. The metal oxide typically contains a transition metal or a mixture of metals, such as rhenium, aluminum, tungsten, molybdenum, or a combination thereof. Typically, the metal oxide is mainly atomically dispersed on the surface of the support, as indicated by STEM. For example, at least 10% of the metal oxide is atomically dispersed on the surface of the support. The method includes (i) exposing a mixture of one or more alcohols or one or more esters and carbon monoxide to the catalyst. Typically, the one or more alcohols or one or more esters and carbon monoxide are in a gas phase. |
| FILED | Monday, November 16, 2020 |
| APPL NO | 17/776933 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/002 (20130101) B01J 23/36 (20130101) Original (OR) Class B01J 23/40 (20130101) B01J 35/617 (20240101) B01J 35/643 (20240101) B01J 2523/74 (20130101) Acyclic or Carbocyclic Compounds C07C 51/12 (20130101) C07C 2523/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083674 | Shelley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Etegent Technologies LTD. (Cincinnati, Ohio) |
| ASSIGNEE(S) | Etegent Technologies, Ltd. (Cincinnati, Ohio) |
| INVENTOR(S) | Stuart J. Shelley (Cincinnati, Ohio); Richard Allan Roth, II (Goshen, Ohio); Kevin Joseph Sigmund (Newtown, Ohio) |
| ABSTRACT | A strut suitable for use in parallel manipulator and other applications utilizes an actuation member that is subjected to a quasi-static axial tensioning force to effectively preload the strut to provide axial stiffness and bending flexibility at one or more ends of the strut. |
| FILED | Thursday, December 12, 2019 |
| APPL NO | 17/298843 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 17/0216 (20130101) B25J 19/0091 (20130101) Original (OR) Class Springs; Shock-absorbers; Means for Damping Vibration F16F 1/44 (20130101) F16F 1/366 (20130101) F16F 2224/025 (20130101) F16F 2224/0241 (20130101) F16F 2228/08 (20130101) F16F 2230/0005 (20130101) F16F 2236/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084186 | Witman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SURVICE Engineering Company, LLC (Belcamp, Maryland) |
| ASSIGNEE(S) | SURVICE Engineering Company, LLC (Belcamp, Maryland) |
| INVENTOR(S) | Joel Henry Witman (Essex, Maryland); Mark Thomas Butkiewicz (North East, Maryland); Robert Eric Baltrusch (Oxford, Pennsylvania) |
| ABSTRACT | A drop kit that attaches to a pair of parallel picatinny rails one drone uses a pair of drop mechanisms that hold one side of a load bearing basket. The opposing side of the basket is pivotally secured to a goggle plate. Each drop mechanism is attached to one of the rails and the goggle plate to both of the rails via a spring-loaded centering clamp system. The drop mechanisms use a drop cam that rotates between and open and closed position so that when the drone arrives at a desired spot, a signal is provided to a pair of motors, each motor associated with one of the drop mechanisms, in order to rotate the drop cam into its open position, releasing its side of the basket with the opposing side of the basket pivoting and then falling free of the goggle plate. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/897707 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/12 (20130101) Original (OR) Class Unmanned aerial vehicles [UAV]; equipment therefor B64U 2101/69 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084203 | Dietsch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornerstone Research Group, Inc. (Miamisburg, Ohio) |
| ASSIGNEE(S) | Cornerstone Research Group, Inc. (Miamisburg, Ohio) |
| INVENTOR(S) | Ben Dietsch (Kettering, Ohio); Bryan Pelley (Sugarcreek Township, Ohio); Karl Gruenberg (Washington Township, Ohio); Jason Hermiller (Lebanon, Ohio) |
| ABSTRACT | Methods of making a composite aircraft primary structure include selecting a compression moldable composite sheet molding compound; preparing a first and a second layup with the compression moldable composite sheet molding compound to form a first and a second 3D preform; and compression molding the first and the second 3D preforms to form a first and a second component part. Further, the first component part comprises first geometric joint features, the second component part comprises second geometric joint features, and the second geometric joint features are complementary to the first geometric joint features such that the second geometric joint features are configured to mate with the first geometric joint features. The method further includes assembling the aircraft primary structure by joining the first component part with the second component part by aligning and mating the first geometric joint features and the second geometric joint features; and securing the same. |
| FILED | Tuesday, April 12, 2022 |
| APPL NO | 17/718477 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 11/12 (20130101) B29B 11/16 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 65/565 (20130101) B29C 65/4835 (20130101) B29C 70/12 (20130101) B29C 70/34 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/12 (20130101) B29K 2307/04 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/3076 (20130101) Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 5/10 (20170101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084314 | Foltz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Lee Foltz (Indian Head, Maryland); Adam Pegouske (White Plains, Maryland) |
| ABSTRACT | A hook assembly includes a first hook having a first open end and a second hook having a second open end. The first hook is parallel to the second hook where the first open end is adjacent to the second open end. Extensions extend from each of the first hook and the second hook. The extensions extend perpendicular to a hook plane of the first hook and the second hook members. The first hook is a mirror image of the second hook. A hinge connects the first hook to the second hook. The hinge is located at an opposite end of the hook from where the extensions are located. A resilient member exerts a constant force at the hinge to bias the first hook and the second hook toward an open position. |
| FILED | Friday, September 29, 2023 |
| APPL NO | 18/445533 |
| ART UNIT | 3651 — Material and Article Handling |
| CURRENT CPC | Cranes; Load-engaging Elements or Devices for Cranes, Capstans, Winches, or Tackles B66C 1/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084343 | Hitch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Reaction Systems, Inc. (Golden, Colorado) |
| ASSIGNEE(S) | Reaction Systems, Inc. (Golden, Colorado) |
| INVENTOR(S) | Bradley Dean Hitch (Golden, Colorado); Jeffrey Robert Engel (Golden, Colorado); David Thomas Wickham (Golden, Colorado) |
| ABSTRACT | A N2O decomposition reactor and a method of its use to produce an effluent suitable for use in an ignition device or in the main fuel injection system in high speed aircraft. N2O decomposition is an exothermic reaction and produces a high temperature product containing high concentrations of O2. Combination of fuel with this effluent ignites quickly and is an effective ignition source for the aircraft combustor. Reactor performance is adjusted to meet the conditions required for a selected application by changing the relative concentrations of CO2 and N2O, modifying the reactor length, and varying the quantity of catalyst in the reactor. For use in a pilot ignition device, the desired effluent temperature is between 500° C. and 1200° C. in order to ignite and combust the fuel within the design residence time, between 0.5 and 10 ms. For application as a barbotage gas generator in a fuel injection system, the temperature of the effluent can range from 300° C. up to 800° C. and it is desirable that the effluent temperature remains within this range for periods of up to two minutes. |
| FILED | Tuesday, February 08, 2022 |
| APPL NO | 17/667308 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 7/00 (20130101) B01J 21/08 (20130101) B01J 23/06 (20130101) B01J 23/464 (20130101) Non-metallic Elements; Compounds Thereof; C01B 13/0203 (20130101) Original (OR) Class C01B 21/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084489 | Kanekiyo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Masaru Kanekiyo (North Bethesda, Maryland); Michael Gordon Joyce (Washington, District of Columbia); Wei Bu (Potomac, Maryland); Jeffrey I. Cohen (Silver Spring, Maryland); Yaroslav Tsybovsky (Brunswick, Maryland) |
| ABSTRACT | Anti-EBV gH antibodies, anti-EBV gL antibodies, anti-EBV gH/gL antibodies, and compositions of matter useful for the detection, diagnosis, prevention, and treatment of Epstein Barr Virus infection in humans, and methods of using those compositions of matter for the same. |
| FILED | Thursday, May 02, 2019 |
| APPL NO | 17/052470 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6803 (20170801) A61K 47/6839 (20170801) Peptides C07K 16/085 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/55 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/705 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56994 (20130101) G01N 2333/05 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084604 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Xuanhe Zhao (Allston, Massachusetts); Hyunwoo Yuk (Cambridge, Massachusetts); Heejung Roh (Cambridge, Massachusetts) |
| ABSTRACT | A dry shape memory adhesive material for adhering a target surface in the presence of fluid and for providing tunable mechanical contraction of an adhered surface. The dry shape memory adhesive material is pre-stretched and dried to provide an adhesive structure that implements a hydration-based shape memory mechanism to achieve both uniaxial and biaxial contractions of the adhered surface. According to preferred embodiments, the shape memory adhesive material includes a combination of one or more hydrophilic polymers or copolymers, one or more amine coupling group, and one or more cross linkers. |
| FILED | Tuesday, February 08, 2022 |
| APPL NO | 17/666642 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/25 (20180101) C09J 7/32 (20180101) Original (OR) Class C09J 2301/12 (20200801) C09J 2301/306 (20200801) C09J 2301/414 (20200801) C09J 2405/00 (20130101) C09J 2433/00 (20130101) C09J 2475/006 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/28 (20150115) Y10T 428/2852 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084701 | Terrell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Labortary (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jessica L. Terrell (Philadelphia, Pennsylvania); Justin P. Jahnke (Bethesda, Maryland) |
| ABSTRACT | A biofabrication method for producing cellulose-based materials. The method includes providing active cellulose-producing bacteria such as Gluconacetobacter and culturing media in a container; combining organic additives or inorganic additives with the active cellulose-producing bacteria in the container to produce a cellulose hydrogel matrix composed of entangled bacteria-produced cellulose nanofibers; controlling a concentration of the additives in the cellulose hydrogel matrix; and exposing the cellulose hydrogel matrix in selected thermal environment to create a biofabricated functional material. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/148720 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/33 (20240101) Non-metallic Elements; Compounds Thereof; C01B 32/05 (20170801) Compositions of Macromolecular Compounds C08L 1/02 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084752 | Saboo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | QUESTEK INNOVATIONS LLC (Evanston, Illinois) |
| ASSIGNEE(S) | QUESTEK INNOVATIONS LLC (Evanston, Illinois) |
| INVENTOR(S) | Abhinav Saboo (Evanston, Illinois); Ricardo Komai (Evanston, Illinois); Dana Frankel (Evanston, Illinois); Marie Thomas (Evanston, Illinois); Greg Olson (Evanston, Illinois) |
| ABSTRACT | Exemplary alloys may comprise, by weight percentage, 13.25% to 14.75% chromium; 4.5% to 5.5% nickel; 0.11% to 0.17% carbon; 0.01% to 0.31% titanium; and the balance of weight percent comprising iron and incidental elements and impurities. Exemplary methods may include conducting additive manufacturing with an atomized alloy powder to generate a manufactured article, where the atomized alloy powder may comprise, by weight percentage, 13.25% to 14.75% chromium; 4.5% to 5.5% nickel; 0.11% to 0.17% carbon; 0.01% to 0.31% titanium; and the balance of weight percent comprising iron and incidental elements and impurities. |
| FILED | Monday, October 31, 2022 |
| APPL NO | 17/977622 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 2201/11 (20130101) B22F 2301/35 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Alloys C22C 38/001 (20130101) C22C 38/002 (20130101) C22C 38/42 (20130101) C22C 38/44 (20130101) C22C 38/46 (20130101) C22C 38/48 (20130101) C22C 38/50 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084775 | Trueman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Elissa M. Trueman (Leesburg, Virginia); Jacob R. Steiner (Bethesda, Maryland); Peter K. Todoroff (Blacksburg, Virginia) |
| ABSTRACT | According to exemplary practice of the present invention, a passivation solution is circulated in a closed loop so as to laminarly flow on a continual basis through the channels of copper-nickel alloy piping or tubing. The passivation solution consists essentially of seawater (natural and/or artificial) plus 0.5 mM nickel hydroxide additive. The cyclical flow of the passivation solution is administered to the piping/tubing for a selected period of time (e.g., seven days), resulting in growth of a corrosion-resistant film on the inside (channel) surfaces of the piping/tubing. The film thus formed consists essentially of nickel hydroxide, nickel oxide, and copper oxide, and represents a durable and effective anti-corrosive barrier when exposed to seawater. |
| FILED | Thursday, June 11, 2020 |
| APPL NO | 16/898874 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 22/63 (20130101) C23C 22/73 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084986 | Hayes |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Special Aerospace Services, LLC (Boulder, Colorado) |
| ASSIGNEE(S) | Special Aerospace Services, LLC (Boulder, Colorado) |
| INVENTOR(S) | Christopher Hayes (Denver, Colorado) |
| ABSTRACT | Methods and systems for manipulating surface topology of additively manufactured fluid interacting structures, such as additively manufactured heat exchangers or airfoils, and associated additively manufactured articles, are disclosed. In one aspect, an article which interacts with a fluid is imparted with surface topology features which affect performance parameters related to the fluid flow. The topological features may be sequenced, combined, intermixed, and functionally varied in size and form to locally manipulate and co-optimize multiple performance parameters at each or selectable differential lengths along a flow path. The co-optimization method may uniquely prioritize selectable performance parameters at different points along the flow path to improve or enhance overall system performance. Topological features may include design features such as dimples, fins, boundary layer disruptors, and biomimicry surface textures, and manufacturing artefacts such as surface roughness and subsurface porosity distribution and morphology. |
| FILED | Sunday, December 17, 2023 |
| APPL NO | 18/542697 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/38 (20130101) B29C 45/2612 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/14 (20130101) Original (OR) Class Jet-propulsion Plants F02K 9/60 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/31 (20130101) F05D 2300/514 (20130101) F05D 2300/516 (20130101) Electric Digital Data Processing G06F 30/15 (20200101) G06F 30/28 (20200101) G06F 2113/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085021 | Heeter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana); Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Robert W. Heeter (Indianapolis, Indiana); Daniel E. Molnar, Jr. (Indianapolis, Indiana); Jonathan M. Rivers (Indianapolis, Indiana) |
| ABSTRACT | A fan case assembly adapted for use with a gas turbine engine includes a case at extends circumferentially at least partway about an axis of the gas turbine engine and a plurality of vanes. The case is formed to define a plenum that that extends circumferentially at least partway about the axis. The plurality of vanes are arranged in the plenum and spaced apart circumferentially about the axis to define a plurality of inlet openings in fluid communication with the plenum. |
| FILED | Wednesday, August 16, 2023 |
| APPL NO | 18/234650 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/057 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085111 | Stupp |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRC, Inc. (North Syracuse, New York) |
| ASSIGNEE(S) | SRC, Inc. (North Syracuse, New York) |
| INVENTOR(S) | Andrew H. Stupp (Syracuse, New York) |
| ABSTRACT | An accessory for tethering a cap for a SMA/SMP bulkhead to a device assembly without having to introduce elements that could compromise the integrity of the device assembly. The accessory includes a first portion that engages the SMA/SMP bulkhead and securely interconnects thereto, and a second portion that includes an opening where a tether chain is physically interconnected thereto. The tether chain includes the cap for the SMA/SMP bulkhead secured to the second end thereof. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875387 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 41/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085209 | Meyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AEROJET ROCKETDYNE, INC. (Sacramento, Connecticut) |
| ASSIGNEE(S) | AEROJET ROCKETDYNE, INC. (Sacramento, California) |
| INVENTOR(S) | David Meyer (Thousand Oaks, California); Mario Padilla (Los Angeles, California); Gary Grenon (Camarillo, California) |
| ABSTRACT | A valve device (20) includes male and female housings (22, 24) that together define a fluid through-passage (28). The male and female housings have, respectively, exterior and interior annular channels (22a, 24a). The male housing is receivable into the female housing such that the exterior and interior annular channels together define a toroidal tube. First and second valve elements (30, 32) are disposed, respectively, in the male and female housings. Ball locks (36) are receivable into the toroidal tube and axially lock the male and female housings together. A lock (40) engageable when the first and second valve elements are in functional alignment and which when engaged rotationally locks the male and female housings. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 17/920456 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 15/033 (20130101) F16K 27/0227 (20130101) Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 37/148 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085279 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| INVENTOR(S) | Jon Anderson (Phoenix, Arizona); Nagaraja Rudrapatna (Phoenix, Arizona); Carlos Vallellanes (Aguadilla, Puerto Rico); Atul Verma (Phoenix, Arizona) |
| ABSTRACT | A combustor for a gas turbine engine includes a combustor liner with a wall defining a combustion chamber. The wall has an inner surface facing the combustion chamber and an outer surface across the wall from the inner surface. Fins are disposed on the outer surface. The wall defines air admission holes that extend through the wall from the outer surface to the inner surface. The wall also defines film cooling holes that extend through the wall from the outer surface to the inner surface. The fins are disposed in areas of the outer surface between the film cooling holes and the air admission holes to cool areas that would otherwise result in hot spots. |
| FILED | Monday, May 08, 2023 |
| APPL NO | 18/313578 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/18 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/35 (20130101) F05D 2260/202 (20130101) F05D 2260/22141 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/002 (20130101) Original (OR) Class F23R 3/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085371 | Adams |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Kevin G. Adams (Dover, New Jersey) |
| ABSTRACT | An ammunition projectile puller includes a body with one or more jaws to engage the projectile. The jaws can generally displace axially or radially relative to an axis of a through opening, and/or rotate around an axis transverse to the through axis, all within a predetermined range of motion. The jaws obtain a reliable purchase on the projectile to facilitate the extraction. The extracted projectile is cleared from the puller by the insertion of the next projectile to be extracted. The device is thus self-locating, self-locking, self-clearing, tolerant of projectile variation, operable with different projectile types and calibers, reliable, and efficient. |
| FILED | Tuesday, July 11, 2023 |
| APPL NO | 18/220446 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 33/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085478 | Gillaugh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | Government of the United States of America as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Daniel Gillaugh (Troy, Ohio); Alexander Kaszynski (Layfayette, Colorado); Jeffrey Brown (Bellbrook, Ohio) |
| ABSTRACT | The present disclosure is directed to a method and system to develop finite element (FE) models of as-manufactured turbomachinery blades using a combination of optical topography measurements, mesh morphing and strain gauge measurements. The method and system improves strain gauge to blade tip timing correlation using as-manufactured blade dimensions with finite element modeling. |
| FILED | Tuesday, April 04, 2023 |
| APPL NO | 18/295293 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/26 (20130101) G01B 11/0691 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/22 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 15/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085729 | Drexler |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Kyle Robert Drexler (San Diego, California) |
| ABSTRACT | An atmospheric distortion compensator comprising a disc and a rotator. The disc, which comprises a phase-modifying structure, is rotationally balanced about a center point. The rotator is mechanically coupled to the disc's center point and configured to spin the disc about an axis. When spinning, the disc is configured to control a property of a beam, which is propagating in parallel to the axis and impinging on the disc. By so doing, scintillation effects within an electro-optical field caused by propagation of the beam within a heterogeneous medium are reduced. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/583421 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/0037 (20130101) G02B 27/4205 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12086570 | Corron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | USA as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Ned J Corron (Madison, Alabama); Jonathan N Blakely (Madison, Alabama) |
| ABSTRACT | An actively stabilized random number generator includes a random number generator and a feedback controller. The random number generator includes a chaotic physical circuit realizing an iterated function. The iterated function is configured to produce a trajectory of iterates and has an operating parameter β and a desired Markov operating point. A binary bit converter has a symbol function configured to produce binary symbols from the trajectory of iterates and a maximal kneading sequence. The feedback controller is configured to observe the maximal kneading sequence within the trajectory of iterates and adjust the operating parameter to the desired Markov operating point. |
| FILED | Tuesday, March 23, 2021 |
| APPL NO | 17/209680 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/588 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087713 | Piedra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Analog Devices, Inc. (Wilmington, Massachusetts) |
| ASSIGNEE(S) | Analog Devices, Inc. (Wilmington, Massachusetts) |
| INVENTOR(S) | Daniel Piedra (Somerville, Massachusetts); James G. Fiorenza (Carlisle, Massachusetts); Puneet Srivastava (Wilmington, Massachusetts); Andrew Proudman (Medford, Massachusetts); Kenneth Flanders (Reading, Massachusetts); Denis Michael Murphy (Concord, Massachusetts); Leslie P. Green (Framingham, Massachusetts); Peter R. Stubler (Andover, Massachusetts) |
| ABSTRACT | Gallium nitride-based monolithic microwave integrated circuits (MMICs) can comprise aluminum-based metals. Electrical contacts for gates, sources, and drains of transistors can include aluminum-containing metallic materials. Additionally, connectors, inductors, and interconnect devices can also comprise aluminum-based metals. The gallium-based MMICs can be manufactured in complementary metal oxide semiconductor (CMOS) facilities with equipment that produces silicon-based semiconductor devices. |
| FILED | Friday, December 30, 2022 |
| APPL NO | 18/148982 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/8252 (20130101) H01L 21/28575 (20130101) H01L 23/66 (20130101) Original (OR) Class H01L 23/481 (20130101) H01L 23/53214 (20130101) H01L 27/0605 (20130101) H01L 27/0629 (20130101) H01L 28/60 (20130101) H01L 29/205 (20130101) H01L 29/452 (20130101) H01L 29/2003 (20130101) H01L 29/4175 (20130101) H01L 29/7786 (20130101) H01L 29/66462 (20130101) H01L 2223/6616 (20130101) H01L 2223/6683 (20130101) H01L 2924/1423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087933 | Tour et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | James M. Tour (Bellaire, Texas); Rodrigo Villegas Salvatierra (Houston, Texas); Gladys Anahi Lopez Silva (Houston, Texas) |
| ABSTRACT | Anodes, cathodes, and separators for batteries (electrochemical energy storage devices). The anodes are Li metal anodes having lithiated carbon films (Li-MWCNT) (as dendrite suppressors and protective coatings for the Li metal anodes). The cathodes are sulfurized carbon cathodes. The separators are GNR-coated (or modified) separators. The invention includes each of these separately (as well as in combination both with each other and with other anodes, cathodes, and separators) and the methods of making each of these separately (and in combination). The invention further includes a battery that uses at least one of (a) the anode having a lithiated carbon film, (b) the sulfurized carbon cathode, and (c) the GNR-modified separator in the anode/cathode/separator arrangement. For instance, a full battery can include the sulfurized carbon cathode in combination with the Li-MWCNT anode or a full battery can include the sulfurized carbon cathode in combination with other anodes (such as a GCNT-Li anode). |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 16/328669 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/58 (20130101) H01M 4/133 (20130101) Original (OR) Class H01M 4/136 (20130101) H01M 4/0404 (20130101) H01M 4/0471 (20130101) H01M 4/583 (20130101) H01M 4/625 (20130101) H01M 10/0525 (20130101) H01M 50/451 (20210101) H01M 2004/028 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12088054 | Richardson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Martin Richardson (Orlando, Florida); Robert Bernath (Orlando, Florida); Nathan Bodnar (Orlando, Florida); Haley Kerrigan (Orlando, Florida); Danielle Reyes (Orlando, Florida); Daniel Thul (Orlando, Florida); Jessica Pena (Orlando, Florida) |
| ABSTRACT | A laser system may include one or more seed lasers to generate a pulsed seed beam. The system may further include a pulse pattern generator to generate an intermediate patterned burst-mode beam from at least one laser pulse from the pulsed seed beam, where the intermediate patterned burst-mode beam includes one or more pulse bursts, and where each of the one or more pulse bursts includes a series of laser pulses with a selected pattern of inter-pulse spacings. The system may further include two or more power amplifiers to amplify the intermediate patterned burst-mode beam to form an amplified patterned burst-mode beam, where at least two of the power amplifiers amplify different portions of the intermediate patterned burst-mode beam, and where the amplified patterned burst-mode beam includes a series of amplified pulse bursts including amplified laser pulses with the selected pattern of inter-pulse spacings. |
| FILED | Monday, November 07, 2022 |
| APPL NO | 17/981738 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0057 (20130101) Original (OR) Class H01S 3/2308 (20130101) H01S 3/10023 (20130101) H01S 3/10084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12088058 | DuBois et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, represented by the Secretary of the Army (, None) |
| INVENTOR(S) | Terry DuBois (Forest Hill, Maryland); Jaclyn Lynch (Baltimore, Maryland); Eric Conrad (Baltimore, Maryland) |
| ABSTRACT | Various embodiments that pertain to cooling of a laser set are described. In one example, the lasers can be a set of laser diodes. A laser diode cooling system can create a vacuum environment that causes a coolant to be below atmospheric pressure. The coolant can be water supplied by an exchangeable tank. When the tank is empty, the tank can be replaced with a new tank. |
| FILED | Tuesday, October 05, 2021 |
| APPL NO | 17/493876 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/02423 (20130101) Original (OR) Class H01S 5/02438 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12088269 | Xiang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intelligent Fusion Technology, Inc. (Germantown, Maryland) |
| ASSIGNEE(S) | Intelligent Fusion Technology, Inc. (Germantown, Maryland) |
| INVENTOR(S) | Xingyu Xiang (Germantown, Maryland); Dan Shen (Germantown, Maryland); Genshe Chen (Germantown, Maryland); Khanh Pham (Kirtland AFB, New Mexico) |
| ABSTRACT | Embodiments of the present disclosure provide a method, a device, and a storage medium for hybrid automatic gain control in a communication system. The method includes amplifying an input signal to generate an amplified signal which is converted into a plurality of output signals; obtaining a moving average amplitude of a plurality of output signals of a current input signal; and calculating a signal amplitude difference according to the moving average amplitude and a desired output signal amplitude level; calculating a signal amplitude ratio according to a plurality of output signals of two previous output signal blocks and AGC gains corresponding to the plurality of output signals of the two previous output signal blocks; obtaining a step size according to the signal amplitude difference and the signal amplitude ratio; and calculating an AGC gain of the current input signal according to the step size and a corresponding previous AGC gain. |
| FILED | Thursday, July 22, 2021 |
| APPL NO | 17/382838 |
| ART UNIT | 2843 — Semiconductors/Memory |
| CURRENT CPC | Amplifiers H03F 3/21 (20130101) Control of Amplification H03G 3/3089 (20130101) Original (OR) Class H03G 2201/103 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12088287 | Sample |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Dwane F. Sample (Spokane, Washington) |
| ABSTRACT | A low-current run plug circuit comprising: a run plug configured to electrically connect 1st and 2nd terminals when the run plug is installed; a safety circuit mounted within the battery-powered apparatus comprising: a JFET a current set resistor a P-channel MOSFET, a voltage divider, and an N-channel MOSFET connected together such that when the run plug is removed the N-channel MOSFET and the P-channel MOSFET are in cutoff wherein no current flows to the electrical load, and such that when the run plug is installed, the safety circuit creates a low-impedance electrical path from the cathode to the electrical load. |
| FILED | Thursday, April 20, 2023 |
| APPL NO | 18/303771 |
| ART UNIT | 2849 — Semiconductors/Memory |
| CURRENT CPC | Pulse Technique H03K 17/063 (20130101) H03K 17/687 (20130101) Original (OR) Class H03K 17/08122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12088695 | Kehlet et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | David Kehlet (Los Altos Hills, California); Shuanghong Sun (Sunnyvale, California); Saikumar Jayaraman (Chandler, Arizona); Fariaz Karim (Gilbert, Arizona) |
| ABSTRACT | A first semiconductor device includes a processor configured to generate a random number at initial test of a second semiconductor device after fabrication of the second semiconductor device in a supply chain related to the second semiconductor device, and send the generated random number to the second semiconductor device. The processor is further configured to receive a first signature that is signed over the sent random number by the second semiconductor device using a first private key that is stored in the second semiconductor device, among a first private and public key pair, and test the received first signature, using a first public key that is stored in the first semiconductor device, among the first private and public key pair, to determine whether the second semiconductor device is authenticated. |
| FILED | Wednesday, December 22, 2021 |
| APPL NO | 17/558627 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 7/586 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0825 (20130101) Original (OR) Class H04L 9/0866 (20130101) H04L 9/3247 (20130101) H04L 9/3263 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12089385 | Zaghloul et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Combat Capabilities Development Command, Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Amir I. Zaghloul (Bethesda, Maryland); Quang Minh Nguyen (Severn, Maryland); Eric D. Adler (Columbia, Maryland) |
| ABSTRACT | A highly-conformal, pliable thin electromagnetic (EM) skin for altering at least one electromagnetic property of a surface includes a pliable thin film, and sub-wavelength elements incorporated into and/or on the pliable thin film which are smaller in scale than the wavelengths of electromagnetic radiation they are intended to influence. The electromagnetic skin readily conforms to contours of a surface to which it attaches or otherwise adheres to. Such electromagnetic skin can be used to cover various surface and platforms on equipment, walls, vehicles, and aircraft to change the electromagnetic properties of such surfaces to achieve certain functions that are not achievable with simple ground plane surfaces. The EM skin may be judiciously configured to alter at least one electromagnetic property of the surface by blocking, absorbing, enhancing, and/or bending waves of electromagnetic radiation. |
| FILED | Wednesday, December 16, 2020 |
| APPL NO | 17/123902 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Windows, Windscreens, Non-fixed Roofs, Doors, or Similar Devices for Vehicles; Removable External Protective Coverings Specially Adapted for Vehicles B60J 11/00 (20130101) Aeroplanes; Helicopters B64C 21/10 (20130101) B64C 2230/12 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 9/0081 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12083223 | Kamrud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Kurt I. Kamrud (San Diego, California); Nathaniel S. Wang (San Diego, California); Martina Felderman (La Jolla, California); Bolyn Hubby (Redwood City, California); Heather D. Gouvis (San Diego, California); Nicholas O. Fischer (Livermore, California); Matthew A. Coleman (Oakland, California); Angela Clare Evans (Livermore, California); Wei He (Davis, California); Amy Rasley (Livermore, California); Craig D. Blanchette (San Leandro, California) |
| ABSTRACT | Nanolipoprotein particles comprising at least a scaffold protein component and a membrane lipid component and related complexes, compositions, methods and systems are described, in which the membrane lipid component comprises at least one or more membrane forming lipids and one or more cationic lipids. |
| FILED | Wednesday, May 02, 2018 |
| APPL NO | 15/969311 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1272 (20130101) Original (OR) Class A61K 9/1274 (20130101) A61K 47/6917 (20170801) A61K 48/0008 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084238 | Flach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (Aiken, South Carolina) |
| ASSIGNEE(S) | Battelle Savannah River Alliance, LLC (Aiken, South Carolina) |
| INVENTOR(S) | Joshua P. Flach (Aiken, South Carolina); Kurt R. Eberl (Aiken, South Carolina); William R. Johnson (Aiken, South Carolina) |
| ABSTRACT | In one aspect, a compact augmented permeation system (CAPS) assembly includes a housing defining an interior cavity. The housing further defines a gas inlet for receiving gas within the interior cavity and a gas outlet for expelling the gas from the interior cavity. Additionally, the CAPS assembly includes a gas-permeable membrane positioned within the housing and defining a system boundary across the interior cavity such that gas received within the interior cavity via the gas inlet permeates through the gas-permeable membrane before being expelled from the interior cavity via the gas outlet. |
| FILED | Wednesday, June 15, 2022 |
| APPL NO | 17/840754 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 39/08 (20130101) B65D 51/24 (20130101) B65D 51/1616 (20130101) Original (OR) Class B65D 2205/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084348 | Zeller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | H QUEST VANGUARD, INC. (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | H QUEST VANGUARD, INC. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Kurt W. Zeller (Pittsburgh, Pennsylvania); George L. Skoptsov (Pittsburgh, Pennsylvania); Evan T. Musselman (Pittsburgh, Pennsylvania) |
| ABSTRACT | Systems and methods for plasma based synthesis of graphitic materials. The system includes a plasma forming zone configured to generate a plasma from radio-frequency radiation, an interface element configured to transmit the plasma from the plasma forming zone to a reaction zone, and the reaction zone configured to receive the plasma. The reaction zone is further configured to receive feedstock material comprising a carbon containing species, and convert the feedstock material to a product comprising the graphitic materials in presence of the plasma. |
| FILED | Monday, June 13, 2022 |
| APPL NO | 17/806619 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 19/126 (20130101) B01J 19/129 (20130101) B01J 2219/0875 (20130101) B01J 2219/0894 (20130101) B01J 2219/0896 (20130101) B01J 2219/0898 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/30 (20130101) H05H 1/4622 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084466 | Even |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Dakota Even (Overland Park, Kansas) |
| ABSTRACT | Methods, systems, and computer-readable media for purification of trimethylsilanol (TMSOH) from a hexamethyldisiloxane (HMDSO) impurity present within an initial feedstock material. A salt-out assisted liquid-liquid extraction (SALLE) process may be used including adding an extraction solution, extracting the HMDSO impurity, and separating/washing to remove the extraction solution and water from the feedstock such that an increased purity product is provided. |
| FILED | Wednesday, September 20, 2023 |
| APPL NO | 18/470776 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/20 (20130101) C07F 7/0836 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084544 | Helms et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Brett A. Helms (Oakland, California); Swagat Sahu (La Jolla, California); Miranda J. Baran (Onartio, Canada); Miles N. Braten (San Francisco, California); Mark E. Carrington (Port of Spain, Trinidad/Tobago); Stephen M. Meckler (Redwood City, California) |
| ABSTRACT | The present disclosure is directed to microporous ladder polymers containing amine-functionalized monomer segments, amidoxime-functionalized monomer segments, or a combination thereof. Monomer compounds for preparation of the polymers are also described, as well as membranes and electrochemical cells containing the polymers. |
| FILED | Friday, August 16, 2019 |
| APPL NO | 17/269228 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Separation B01D 67/00091 (20220801) B01D 69/02 (20130101) B01D 71/5211 (20220801) B01D 2325/02831 (20220801) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 39/07 (20170101) B01J 39/19 (20170101) Acyclic or Carbocyclic Compounds C07C 215/64 (20130101) Heterocyclic Compounds C07D 211/46 (20130101) C07D 295/135 (20130101) C07D 295/205 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/48 (20130101) Original (OR) Class C08G 65/4006 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/24 (20130101) H01M 50/403 (20210101) H01M 50/414 (20210101) H01M 50/491 (20210101) H01M 2300/0014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084708 | Branch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Darren W. Branch (Albuquerque, New Mexico); Bryan Carson (Tijeras, New Mexico); DeAnna Marie Campbell (Albuquerque, New Mexico); Kurt Wessendorf (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates to systems including an acoustic wave resonator and an active shunt capacitance cancelling oscillator circuit. Such systems can be used in biosensing methods, while avoiding impedance distortion and phase shift anomalies. |
| FILED | Tuesday, November 03, 2020 |
| APPL NO | 17/088221 |
| ART UNIT | 2849 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2300/0663 (20130101) B01L 2400/0436 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/32 (20130101) G01N 29/036 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/326 (20130101) H03B 5/362 (20130101) H03B 5/1203 (20130101) H03B 2200/0022 (20130101) H03B 2200/0038 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/25 (20130101) H03H 9/145 (20130101) H03H 9/02543 (20130101) H03H 9/02551 (20130101) H03H 9/02559 (20130101) H03H 9/02637 (20130101) H03H 9/02937 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084743 | Leibman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Christopher Leibman (Santa Fe, New Mexico); Janelle Droessler (Los Alamos, New Mexico); Iain May (Los Alamos, New Mexico); Nicholas Hubley (Santa Fe, New Mexico) |
| ABSTRACT | Disclosed herein are embodiments of methods for isolating rare earth elements (REEs) and radioisotopes from coal combustion products, such as fly ash. In particular embodiments, lanthanides, Al, Sc, Y, or compounds comprising lanthanides, AI, Sc, Y, or any combination thereof; or actinides can be isolated using the methods disclosed herein. |
| FILED | Monday, March 15, 2021 |
| APPL NO | 17/201729 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/14 (20130101) Original (OR) Class C22B 3/20 (20130101) C22B 59/00 (20130101) C22B 60/0252 (20130101) C22B 60/0291 (20130101) C22B 60/0295 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085333 | Cahill et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | James T. Cahill (Livermore, California); Swetha Chandrasekaran (Dublin, California); Wyatt L. Du Frane (Livermore, California); Joshua D. Kuntz (Livermore, California); Richard L. Landingham (Livermore, California); Ryan Lu (Daly City, California); Christopher M. Spadaccini (Oakland, California); Amy Wat (Oakland, California); Seth E. Watts (Collingswood, New Jersey); Marcus A Worsley (Hayward, California) |
| ABSTRACT | A semi-passive cooling system for a component exposed to a fluid flow utilizes a hierarchical vasculature and a sacrificial transpirant to cool the component. The component includes a body that defines a transpirant reservoir and the hierarchical vasculature. The transpirant is configured to transition between a solid phase and a vapor phase over an operating temperature range of the component. |
| FILED | Tuesday, September 08, 2020 |
| APPL NO | 17/014756 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 3/00 (20130101) F25D 7/00 (20130101) Original (OR) Class F25D 2303/084 (20130101) F25D 2303/08222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
12085624 — Systems, methods, and devices for failure detection of one or more energy storage devices
| US 12085624 | Kowalski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Titan Advanced Energy Solutions, Inc. (Salem, Massachusetts) |
| ASSIGNEE(S) | Titan Advanced Energy Solutions, Inc. (Salem, Massachusetts) |
| INVENTOR(S) | Jeffrey A. Kowalski (Somerville, Massachusetts); Steven A. Africk (Boston, Massachusetts); Jay F. Whitacre (Pittsburgh, Pennsylvania); Thomas C. Ferree (Waltham, Massachusetts); Maura Appleberry (Louisville, Kentucky); Shawn D. Murphy (Salem, Massachusetts); Sean O'Day (Boca Raton, Florida) |
| ABSTRACT | An energy storage device management system can include a management portion for charging/discharging an energy storage device and an ultrasound interrogation portion for passing ultrasound energy through the energy storage device during charge/discharge cycles. A memory stores a stream of capture data instances derived from ultrasound energy exiting the energy storage device and baseline ultrasound data instances corresponding with the energy storage device during normal charging/discharging thereof. A processor can compare each capture data instance with the baseline ultrasound data and detect abnormal operating states of the energy storage device. A warning system can issue a notification when abnormal operating states are detected. |
| FILED | Saturday, April 30, 2022 |
| APPL NO | 17/734005 |
| ART UNIT | 2896 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/367 (20190101) G01R 31/382 (20190101) G01R 31/396 (20190101) Original (OR) Class G01R 31/3646 (20190101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0031 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085900 | Wenzel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Johnson Controls Technology Company (Auburn Hills, Michigan) |
| ASSIGNEE(S) | Johnson Controls Technology Company (Auburn Hills, Michigan) |
| INVENTOR(S) | Michael J. Wenzel (Oak Creek, Wisconsin); Kirk H. Drees (Cedarburg, Wisconsin) |
| ABSTRACT | A system includes a processing circuit configured to provide an energy use setpoint based on energy data including an energy characteristic and subject to a constraint based on a variable condition of a building. The processing circuit is configured to estimate a value for the energy use setpoint that will result in the variable condition of the building satisfying the constraint and provide a control signal for equipment based on a difference between the energy use setpoint and a measured energy use. |
| FILED | Thursday, July 29, 2021 |
| APPL NO | 17/389093 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/30 (20180101) F24F 11/38 (20180101) F24F 11/46 (20180101) F24F 11/47 (20180101) F24F 11/58 (20180101) F24F 11/62 (20180101) F24F 11/63 (20180101) F24F 2120/00 (20180101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/021 (20130101) Original (OR) Class Systems for Controlling or Regulating Non-electric Variables G05D 23/1923 (20130101) Systems for Regulating Electric or Magnetic Variables G05F 1/66 (20130101) Electric Digital Data Processing G06F 1/3203 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0201 (20130101) G06Q 30/0202 (20130101) G06Q 30/0206 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/14 (20130101) H04L 12/2803 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 90/84 (20151101) Y02P 90/845 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12086267 | White et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| INVENTOR(S) | Gregory K. White (Livermore, California); Steven A. Kreek (Livermore, California) |
| ABSTRACT | A system is provided for simulating a cyberattack as a simulated cyberattack on a real industrial control facility that includes reals sensor devices. The system generates simulated sensor signals that are representative of sensor signals generated by a sensor of a real sensor device that is the target of the simulated cyberattack. The system injects the simulated sensor signals into the real sensor device so that the real sensor device generates an output based on the simulated sensor signals. The system monitors the response of a personnel of the industrial control facility. The system then generates an assessment of the response based on a target response. The system may rerun the simulated cyberattack based on the assessment. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 17/669097 |
| ART UNIT | 2497 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class G06F 2221/034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12086513 | Rackauckas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | JuliaHub, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | JuliaHub, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Christopher Rackauckas (Cambridge, Massachusetts); Viral B. Shah (Cambridge, Massachusetts); Yingbo Ma (Newton, Massachusetts) |
| ABSTRACT | Methods, systems, and computing devices of a solver for detecting discontinuities or irregularities in a simulation in scientific computing is disclosed. The solver detects a discontinuity or irregularity using two phases: a crude phase, and a fine phase. The crude phase determines an estimate of where the discontinuity is located by extrapolating the interpolant. The fine phase iteratively refines the location of the discontinuity using root-finding and simplified Newton iterations. The solver disclosed herein takes fewer steps when running a simulation because it accurately steps over the discontinuities. |
| FILED | Friday, March 15, 2024 |
| APPL NO | 18/606394 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12086909 | Jimenez, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Edward Steven Jimenez, Jr. (Albuquerque, New Mexico); Cody M. Washburn (Albuquerque, New Mexico) |
| ABSTRACT | A computer-implemented method of reconstructing boundaries from a computed tomography (CT) image dataset is provided. The method comprises receiving CT image data and applying a number of image filters to the CT image data. A numerical derivative is applied to the filtered CT image data to flatten and suppress non-edge regions that do not correspond to edges. Numerical derivative values are clipped to a specified range to reduce artifacts and noise, and an X-ray image is reconstructed according to the image filters and clipped numerical derivative values. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/675434 |
| ART UNIT | 2671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 11/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087146 | Harrison et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Matthew S. Harrison (Oak Ridge, Tennessee); Anthony D. McBee (Oak Ridge, Tennessee); Darren D. Loposser (Oak Ridge, Tennessee); Michael E. Bowling (Oak Ridge, Tennessee); Nikolas J. Smith (Oak Ridge, Tennessee) |
| ABSTRACT | A system for redundantly detecting a gas is provided. The system includes first and second series-connected gas sensors and a signaling module. If both gas sensors are functioning normally, the signaling module provides an alert when both gas sensors detect a predetermined gas concentration. If however any one of the gas sensors is experiencing a fault condition, the faulty gas sensor's alarm is shunted by operation of a fault relay, and the signaling module provides an alert when the non-faulty gas sensor detects a predetermined gas concentration. If both gas sensors are experiencing a fault condition, both gas sensors' alarms are shunted by fault relays, and an audible and/or visual alert is generated by the signaling module. Embodiments of the present invention are well suited for industrial facilities, manufacturing facilities, research and development laboratories, and other locations where unsafe gas concentrations may become present. |
| FILED | Thursday, October 06, 2022 |
| APPL NO | 17/960886 |
| ART UNIT | 2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0031 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/14 (20130101) Original (OR) Class G08B 29/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087462 | Diamond |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kanasa City, Missouri) |
| INVENTOR(S) | Louis Diamond (Kansas City, Missouri) |
| ABSTRACT | A radiopaque processing medium comprising a plurality of radiopaque particles and a non-radiopaque processing medium. The plurality of radiopaque particles is added to the non-radiopaque processing medium to increase a bulk density of the processing medium thereby forming the radiopaque processing medium. The radiopaque processing medium allows excess process media to be located and characterized during X-ray inspection of an electronic device on which the radiopaque processing medium was used. The radiopaque processing medium may also be used to locate and identify flaws/defects of the electronic device based on the location of excess radiopaque processing medium. The radiopaque processing medium may also be used as an underfill material to reinforce electronic chips soldered to the electronic device. |
| FILED | Friday, May 03, 2024 |
| APPL NO | 18/654715 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 3/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087489 | Beddingfield et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | NORTH CAROLINA STATE UNIVERSITY (Raleigh, North Carolina); U.S. DEPARTMENT OF ENERGY (Washington, District of Columbia) |
| INVENTOR(S) | Richard Byron Beddingfield (Raleigh, North Carolina); Subhashish Bhattacharya (Raleigh, North Carolina); Tsz Sing Wong (Raleigh, North Carolina); Paul Ohodnicki (Allison Park, Pennsylvania) |
| ABSTRACT | Various examples are provided related to transformer designs that offer very high isolation while maintaining high coupling between the windings. In one example, an isolation transformer includes a first excitation coil wound around a first core and a second excitation coil wound about a second core. The second core is electrically separated from the first core by a high resistivity magnetic material or a non-conductive material. The first and second cores can include corresponding core segments arranged in a trident geometry or a quindent geometry. The core segments can align when the first excitation coil is inserted into a void of the second excitation coil. The isolation transformer designs are mechanically separable which can result in safe, energized, plug operations. |
| FILED | Wednesday, July 08, 2020 |
| APPL NO | 16/923893 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/02 (20130101) H01F 27/24 (20130101) H01F 27/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087501 | Wolf |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Joseph Ambrose Wolf (Olathe, Kansas) |
| ABSTRACT | Systems and methods of additively manufacturing passive electronic components are provided. An additive manufacturing device may deposit a material to create a passive electronic component. A sensor may continuously measure an electrical property of the passive electronic component across two electrical contacts as the material is deposited during manufacturing. The sensor may transmit the measured electrical property to a processor whereby the processor may adjust a material deposition rate of the additive manufacturing device. The continuous measurement of the electrical property and adjustment of the material deposition rate as the passive electronic component is produced allows for passive electronic components to be manufactured to a high degree of accuracy of the electrical property. |
| FILED | Friday, March 18, 2022 |
| APPL NO | 17/698326 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/85 (20210101) B22F 12/90 (20210101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) B28B 17/0081 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/393 (20170801) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/3406 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) B33Y 80/00 (20141201) Resistors H01C 17/065 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 41/043 (20130101) Original (OR) Class Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/33 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/162 (20130101) H05K 1/165 (20130101) H05K 1/167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087828 | Balachandran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Uthamalingam Balachandran (Willowbrook, Illinois); Stephen E. Dorris (LaGrange Park, Illinois); Beihai Ma (Naperville, Illinois); Tae H. Lee (Naperville, Illinois); David R. Forrest (Washington, District of Columbia); Christopher Klingshirn (College Park, Maryland) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois); U.S. Department of Energy (Washington, District of Columbia) |
| INVENTOR(S) | Uthamalingam Balachandran (Willowbrook, Illinois); Stephen E. Dorris (LaGrange Park, Illinois); Beihai Ma (Naperville, Illinois); Tae H. Lee (Naperville, Illinois); David R. Forrest (Washington, District of Columbia); Christopher Klingshirn (College Park, Maryland) |
| ABSTRACT | A method for preparing a covetic, nanocarbon-infused, metal composite material is described is herein. The method comprises heating a stirring molten mixture of a metal (e.g., Cu, Al, Ag, Au, Fe, Ni, Pt, Sn, Pb, Zn, Si, and the like) and carbon (e.g., graphite) at a temperature sufficient to maintain the mixture in the molten state in a reactor vessel, while passing an electric current through the molten mixture via at least two spaced electrodes submerged or partially submerged in the molten metal. Each of the electrodes has an electrical conductivity that is at least about 50 percent of the electrical conductivity of the molten mixture at the temperature of the molten mixture. Preferably, the conductivity of the electrodes is equal to or greater than the conductivity of the molten mixture. |
| FILED | Tuesday, December 04, 2018 |
| APPL NO | 16/209657 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/20 (20170801) Production and Refining of Metals; Pretreatment of Raw Materials C22B 9/16 (20130101) Alloys C22C 9/01 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/401 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087910 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Xia Cao (Richland, Washington); Ji-Guang Zhang (Richland, Washington); Wu Xu (Richland, Washington) |
| ABSTRACT | Electrolytes for lithium ion batteries with carbon-based, silicon-based, or carbon- and silicon-based anodes include a lithium salt; a nonaqueous solvent comprising at least one of the following components: (i) an ester, (ii) a sulfur-containing solvent, (iii) a phosphorus-containing solvent, (iv) an ether, (v) a nitrile, or any combination thereof, wherein the lithium salt is soluble in the solvent; a diluent comprising a fluoroalkyl ether, a fluorinated orthoformate, a fluorinated carbonate, a fluorinated borate, a fluorinated phosphate, a fluorinated phosphite, or any combination thereof, wherein the lithium salt has a solubility in the diluent at least 10 times less than a solubility of the lithium salt in the solvent; and an additive having a different composition than the lithium salt, a different composition than the solvent, and a different composition than the diluent. In some electrolytes, the nonaqueous solvent comprises an ester. |
| FILED | Wednesday, May 31, 2023 |
| APPL NO | 18/326738 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/386 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/587 (20130101) H01M 10/0567 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 2300/0042 (20130101) H01M 2300/0051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087948 | Tellekamp, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); COLORADO SCHOOL OF MINES (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Colorado School of Mines (Golden, Colorado) |
| INVENTOR(S) | Marshall Brooks Tellekamp, Jr. (Denver, Colorado); Adele Clare Tamboli (Golden, Colorado); Chunmei Ban (Golden, Colorado); Celeste Louise Melamed (Golden, Colorado); Anna Osella (Rochester, Michigan) |
| ABSTRACT | Disclosed herein are methods for making Zn1−xSn1+xN2. |
| FILED | Monday, August 03, 2020 |
| APPL NO | 16/983672 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) Original (OR) Class H01M 4/136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12088027 | Khaligh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); Fariborz Musavi (Redmond, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| INVENTOR(S) | Alireza Khaligh (Arlington, Virginia); Fariborz Musavi (Redmond, Washington) |
| ABSTRACT | In some embodiments, systems and methods for connector assembly for use with an AC or DC power interface of a power conversion device, such as a converter and an inverter, are provided. The connector assembly can include a circuit board, a power connector, and a pin. The power connector can have a base configured to be secured relative to the circuit board and define a first channel extending through the power connector along a first channel axis. The first pin can have a first pin body that extends along a first pin axis and a first connection element that extends along the first pin axis from the first pin body to a first terminal end that is skewed relative to the first pin axis. |
| FILED | Friday, April 28, 2023 |
| APPL NO | 18/309337 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/7082 (20130101) Original (OR) Class H01R 13/2471 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/32 (20141201) H02S 40/36 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12089160 | Odelberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Trevor Odelberg (Ann Arbor, Michigan); David Wentzloff (Ann Arbor, Michigan) |
| ABSTRACT | A low-power standard-compliant NB-IoT wake-up receiver (WRX) is presented. The WRX is designed as a companion radio to a full NB-IoT receiver, only operating during discontinuous RX modes (DRX and eDRX), which allows the full high-power radio to turn off while the wake-up receiver efficiently receives NB-IoTWake-Up Signals (WUS). The fabricated receiver achieves 2.1 mW power at −109 dBm sensitivity with 180 kHz bandwidth over the 750-960 MHz bands. The WRX is fabricated in 28 nm CMOS and consumes 5× less power than the best previously published traditional NB-IoT receivers. This disclosure is the first designed dedicated wake-up receiver for the NB-IoT protocol and demonstrates the benefits of utilizing a WRX to reduce power consumption of NB-IoT radios. |
| FILED | Wednesday, March 30, 2022 |
| APPL NO | 17/708017 |
| ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Information and Communication Technology Specially Adapted for the Internet of Things [IOT] G16Y 10/75 (20200101) Amplifiers H03F 3/19 (20130101) H03F 2200/294 (20130101) H03F 2200/451 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/08 (20130101) Wireless Communication Networks H04W 52/0235 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12083336 | Cruttenden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Corey Edward Cruttenden (Minneapolis, Minnesota); Rajesh Rajamani (Saint Paul, Minnesota); Wei Chen (Plymouth, Minnesota); Xiao-Hong Zhu (Plymouth, Minnesota); Mahdi Ahmadi (Minneapolis, Minnesota) |
| ABSTRACT | A device includes a substrate, an electrode, an electrical pad, and a signal line. The signal line is coupled to the substrate and covered by an insulation layer. The signal line is coupled to the electrical pad and the electrode. At least one of the electrode and the signal line includes a diamagnetic material and paramagnetic material, wherein a ratio of the diamagnetic material and the paramagnetic material is selected based on the susceptibility properties of a physiological tissue. The term paramagnetic herein refers to magnetic susceptibility greater than that of the surrounding tissue and diamagnetic refers to magnetic susceptibility lower than that of the tissue. |
| FILED | Tuesday, August 16, 2022 |
| APPL NO | 17/820115 |
| ART UNIT | 3796 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) A61B 5/6868 (20130101) A61B 5/6877 (20130101) A61B 5/7207 (20130101) A61B 2562/125 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/086 (20170801) A61N 1/0534 (20130101) Original (OR) Class A61N 1/0551 (20130101) A61N 1/36003 (20130101) A61N 1/36053 (20130101) A61N 1/36062 (20170801) A61N 1/36067 (20130101) A61N 1/36103 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083339 | Ivey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia); Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia); Wake Forest University Health Sciences (Winston-Salem, North Carolina) |
| INVENTOR(S) | Jill W. Ivey (Blacksburg, Virginia); Eduardo L. Latouche (Blacksburg, Virginia); Scott S. Verbridge (Blacksburg, Virginia); Rafael V. Davalos (Blacksburg, Virginia); Glenn J. Lesser (Winston-Salem, North Carolina); Waldemar Debinski (Blacksburg, Virginia) |
| ABSTRACT | Described herein are methods of electroporation that can include the steps of contacting a cell that is responsive to an EphA2 receptor ligand with an amount of an EphA2 receptor ligand and applying high-frequency irreversible electroporation to the cell. Also described herein are methods of treating cancer in a subject in need thereof, wherein the methods can include the steps of administering an amount of an EphA2 receptor ligand and applying high-frequency irreversible electroporation to a location on or within the subject. |
| FILED | Friday, October 06, 2017 |
| APPL NO | 16/340106 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/12 (20130101) A61B 18/1233 (20130101) A61B 2017/00172 (20130101) A61B 2018/126 (20130101) A61B 2018/128 (20130101) A61B 2018/00613 (20130101) A61B 2018/00732 (20130101) A61B 2018/00767 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/19 (20130101) A61K 38/1793 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/05 (20130101) A61N 1/06 (20130101) A61N 1/327 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083515 | Du et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (Boca Raton, Florida) |
| ASSIGNEE(S) | FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (Boca Raton, Florida) |
| INVENTOR(S) | E Du (Boca Raton, Florida); Darryl Dieujuste (Boca Raton, Florida); Jia Liu (Boca Raton, Florida); Yuhao Qiang (Boca Raton, Florida) |
| ABSTRACT | An exemplary mobile impedance-based flow cytometer is developed for the diagnosis of sickle cell disease. The mobile cytometer may be controlled by a computer (e.g., smartphone) application. Calibration of the portable device may be performed using a component of known impedance value. With the developed portable flow cytometer, analysis may be performed on two sickle cell samples and a healthy cell sample. The acquired results may subsequently be analyzed to extract single-cell level impedance information as well as statistics of different cell conditions. Significant differences in cell impedance signals may be observed between sickle cells and normal cells, as well as between sickle cells under hypoxia and normoxia conditions. |
| FILED | Tuesday, March 07, 2023 |
| APPL NO | 18/118277 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Original (OR) Class B01L 3/502761 (20130101) B01L 2300/06 (20130101) B01L 2300/16 (20130101) B01L 2300/025 (20130101) B01L 2300/0645 (20130101) B01L 2300/0809 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1031 (20130101) G01N 15/1425 (20130101) G01N 15/1431 (20130101) G01N 15/1484 (20130101) G01N 33/4915 (20130101) G01N 2015/012 (20240101) G01N 2015/1006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083516 | Du et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (Boca Raton, Florida) |
| ASSIGNEE(S) | FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (Boca Raton, Florida) |
| INVENTOR(S) | E Du (Boca Raton, Florida); Darryl Dieujuste (Boca Raton, Florida); Jia Liu (Boca Raton, Florida); Yuhao Qiang (Boca Raton, Florida) |
| ABSTRACT | An exemplary mobile impedance-based flow cytometer is developed for the diagnosis of sickle cell disease. The mobile cytometer may be controlled by a computer (e.g., smartphone) application. Calibration of the portable device may be performed using a component of known impedance value. With the developed portable flow cytometer, analysis may be performed on two sickle cell samples and a healthy cell sample. The acquired results may subsequently be analyzed to extract single-cell level impedance information as well as statistics of different cell conditions. Significant differences in cell impedance signals may be observed between sickle cells and normal cells, as well as between sickle cells under hypoxia and normoxia conditions. |
| FILED | Tuesday, March 07, 2023 |
| APPL NO | 18/118279 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) Original (OR) Class B01L 3/502761 (20130101) B01L 2300/06 (20130101) B01L 2300/16 (20130101) B01L 2300/025 (20130101) B01L 2300/0645 (20130101) B01L 2300/0809 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1031 (20130101) G01N 15/1425 (20130101) G01N 15/1431 (20130101) G01N 15/1484 (20130101) G01N 33/4915 (20130101) G01N 2015/012 (20240101) G01N 2015/1006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083565 | Quigley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Nicole Neff (North Potomac, Maryland); Jack Rowbottom (Swansea, Massachusetts) |
| ABSTRACT | A control system for controlling extraction of landfill gas from a landfill via a gas extraction system, the gas extraction system comprising well piping for coupling a plurality of wells to a gas output. The control system comprises a controller configured to: obtain a value indicating measured energy content of landfill gas collected at the gas output from the plurality of wells; determine whether the measured energy content is different from a target energy content; and in response to determining that the measured energy content is different from the target energy content: control a plurality of valves disposed in the well piping to change flow rates of landfill gas being extracted from at least some of the plurality of wells at least in part by changing degrees to which the plurality of valves are open. |
| FILED | Tuesday, October 04, 2022 |
| APPL NO | 17/959446 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/02 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/30 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084181 | Chilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Oklahoma City, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Phillip B. Chilson (Norman, Oklahoma); Antonio R. Segales Espinosa (Norman, Oklahoma); William J. Doyle (Norman, Oklahoma); Tyler M. Bell (Norman, Oklahoma); Brian R. Murillo Greene (Norman, Oklahoma); Joshua J. Martin (Norman, Oklahoma); Elizabeth A. Pillar-Little (Norman, Oklahoma); Gustavo Britto Hupsel de Azevedo (Norman, Oklahoma) |
| ABSTRACT | An unmanned aerial system (UAS) adapted to measure one or more atmospheric conditions has a frame and a plurality of motorized rotors suspended on arms extending outward from the frame. The UAS further includes a flight control module that includes a computer programmable flight control board and a sensor package that has an air sampling scoop, a first sensor positioned inside the air sampling scoop, and a ducted fan inside the air sampling scoop. The ducted fan is configured to draw air through the air sampling scoop in contact with the first sensor. The ducted fan can be configured to operate only when the UAS is above a predetermined altitude. The UAS may also be configured to operate in a “wind vane” mode in which wind speed and direction is determined based on the pitch and heading of the UAS. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/146352 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Original (OR) Class Unmanned aerial vehicles [UAV]; equipment therefor B64U 10/13 (20230101) B64U 30/20 (20230101) B64U 2101/35 (20230101) B64U 2201/10 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084382 | Burton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Marvin Burton (Glendale, Arizona); Christian Hoover (Chandler, Arizona); Elham Fini (Phoenix, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Marvin Burton (Glendale, Arizona); Christian Hoover (Chandler, Arizona); Elham Fini (Phoenix, Arizona) |
| ABSTRACT | Treating plastic particles for use in concrete includes combining plastic particles with oil to yield a mixture, heating the mixture to yield a heated mixture, cooling the heated mixture to yield a cooled mixture, and removing excess oil from the cooled mixture to yield oil-treated plastic particles (e.g., oil-treated plastic particles for concrete). In one example, the oil is vegetable oil. The vegetable oil can be soybean oil, corn oil, canola oil, safflower oil, peanut oil, olive oil, grape seed oil, cocoa butter, palm oil, rice bran oil, or a combination thereof. The oil can be waste oil (e.g., waste vegetable oil, such as that recovered from restaurants). The plastic particles can be derived from post-consumer plastic, such as recycled plastic. In one example, the post-consumer plastic includes mixed plastics. A concrete composition can include rocks, sand, cement, and the oil-treated plastic particles. |
| FILED | Friday, October 27, 2023 |
| APPL NO | 18/496614 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Disposal of Solid Waste B09B 3/21 (20220101) B09B 3/40 (20220101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 16/04 (20130101) C04B 18/30 (20130101) Original (OR) Class C04B 20/1025 (20130101) C04B 20/1025 (20130101) C04B 28/02 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/91 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084421 | Odom et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Aaron Odom (East Lansing, Michigan); Jetze J. Tepe (East Lansing, Michigan); Theresa A. Lansdell (East Lansing, Michigan) |
| ABSTRACT | Described herein are quinoline compounds useful for, among other things, inhibition of the proteasome and for treatment of cancer and inflammation. |
| FILED | Thursday, February 04, 2021 |
| APPL NO | 17/167271 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 215/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085534 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Shoujun Xu (Houston, Texas); Yuhong Wang (Houston, Texas); Haina Jia (Houston, Texas); Heng Yin (Houston, Texas); Yujia Mao (Houston, Texas) |
| ABSTRACT | A method of measuring dissociation of the biomolecular bonds in one or multiple sample wells using super-resolution force spectroscopy (SURFS). SURFS utilizes precise ultrasound radiation to exert an acoustic radiation force on the biomolecular bonds labeled with magnetic particles. The force-induced dissociation of the protein bonds labeled with magnetic particles may be measured as a reduced magnetic signal by a magnetic sensor. The force resolution allows for differentiating biomolecular bonds with an extremely high level of precision. The biomolecular bonds include protein-protein, protein-nucleic acid, nucleic acid-nucleic acid, small molecule-protein, and small molecule-nucleic acid interactions. |
| FILED | Wednesday, February 06, 2019 |
| APPL NO | 16/968535 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0207 (20130101) B06B 1/0622 (20130101) B06B 1/0651 (20130101) B06B 2201/77 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/72 (20130101) Original (OR) Class G01N 33/15 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085544 | Mohana Rangan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Srivatsan Mohana Rangan (Tempe, Arizona); Anca Delgado (Tempe, Arizona); Rosa Krajmalnik-Brown (Chandler, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Srivatsan Mohana Rangan (Tempe, Arizona); Anca Delgado (Tempe, Arizona); Rosa Krajmalnik-Brown (Chandler, Arizona) |
| ABSTRACT | Methods and systems for the detection and quantification of multiplicity of ionic analytes comprising CrO42−, AsO43−, SeO42−, and ClO4−, and optionally F−, Cl−, NO2−, NO3−, SO42−, using ion chromatography and suppressed ion conductivity. The method comprises loading a sample loop with a sample; injecting the sample from the sample loop into a column with an eluent, wherein the column comprises a guard column and an analytical column; separating, with the column, the injected sample at an effective separation temperature the injected sample in the presence of an organic modifier into a multiplicity of detectable ionic analytes; suppressing, with a suppressor, background signal; and detecting, with a detector, the multiplicity of ionic analytes. |
| FILED | Monday, October 11, 2021 |
| APPL NO | 17/498203 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/54 (20130101) Original (OR) Class G01N 30/64 (20130101) G01N 30/8679 (20130101) G01N 33/182 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085552 | Haley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Michael M. Haley (Eugene, Oregon); Michael Pluth (Eugene, Oregon); Darren W. Johnson (Eugene, Oregon); Sean Fontenot (Eugene, Oregon) |
| ABSTRACT | A device that includes a polymeric layer, wherein the polymeric layer comprises (A) a polymer and, incorporated within the polymeric layer, (B) a compound, or a protonate or salt thereof, wherein the compound, or a protonate or salt thereof, has a structure that includes at least one moiety configured for reversible, non-covalent binding of the anionic sulfide species. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/536994 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 275/28 (20130101) C07C 275/34 (20130101) Heterocyclic Compounds C07D 213/40 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/414 (20130101) G01N 33/182 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 436/184 (20150115) Y10T 436/156666 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085557 | Rajaraman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | Swaminathan Rajaraman (Winter Park, Florida); Lei Zhai (Oviedo, Florida); Avra Kundu (Orlando, Florida); Nilab Azim (Ovideo, Florida) |
| ABSTRACT | Disclosed herein is a microelectrode platform that may be used for multiple biosystem applications including cell culturing techniques and biosensing. Also disclosed are microfabrication techniques for inexpensively producing microelectrode platforms. |
| FILED | Monday, May 06, 2019 |
| APPL NO | 16/404729 |
| ART UNIT | 1781 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) B01L 2300/0645 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 2003/0806 (20130101) Apparatus for Enzymology or Microbiology; C12M 1/3407 (20130101) C12M 3/00 (20130101) C12M 41/46 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/38 (20130101) C12N 13/00 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0007 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/27 (20130101) G01N 27/128 (20130101) G01N 33/4836 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/293 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/24339 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085561 | Forouzanfar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shahrzad Forouzanfar (Miami, Florida); Iman Khakpour (Miami, Florida); Nezih Pala (Miami, Florida); Chunlei Wang (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Shahrzad Forouzanfar (Miami, Florida); Iman Khakpour (Miami, Florida); Nezih Pala (Miami, Florida); Chunlei Wang (Miami, Florida) |
| ABSTRACT | Biosensors capable of detecting certain biomarkers (e.g., platelet-derived growth factor-BB (PDGF-BB)), as well as methods of fabricating the same and methods of using the same, are provided. The biosensors can be disposable and/or label-free. Electrochemical bipolar exfoliation can be used to exfoliate, reduce, and deposit (in a single step) graphene nanosheets on a desired substrate (e.g., an electrode). Affinity aptamers can be immobilized on the graphene nanosheets disposed on the substrate. |
| FILED | Monday, March 20, 2023 |
| APPL NO | 18/186283 |
| ART UNIT | 1759 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/308 (20130101) G01N 27/3276 (20130101) G01N 33/5438 (20130101) Original (OR) Class G01N 33/57484 (20130101) G01N 2333/49 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12088354 | Abdi |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ali Abdi (Short Hills, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ali Abdi (Short Hills, New Jersey) |
| ABSTRACT | A method and a system are disclosed for high speed acoustic transmission of data in networks and sequences of solid pieces using various propagation modes. The data is converted to several sets, and then the sets are transmitted via propagation modes such as extensional or flexural or torsional or their combinations, using multiple transmitters. This allows to increase transmission rate or reduce transmission error or both for data communication. |
| FILED | Tuesday, August 20, 2019 |
| APPL NO | 17/269723 |
| ART UNIT | 2687 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 47/16 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/22 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/18 (20130101) Transmission H04B 11/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12083495 | Cosgrove et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ADVANCED FUEL RESEARCH, INC. (East Hatford, Connecticut) |
| ASSIGNEE(S) | Advanced Fuel Research, Inc (East Hartford, Connecticut) |
| INVENTOR(S) | Joseph E. Cosgrove (Colombia, Connecticut); Marek A. Wójtowicz (East Hartford, Connecticut); Michael A. Serio (Sturbridge, Massachusetts); Andrew E. Carlson (Higganum, Connecticut) |
| ABSTRACT | High purity carbon sorbent monoliths that are particularly effective for the adsorption and subsequent desorption of trace-contaminants, such as ammonia, are produced by 3D-printing polymer monoliths, carbonizing them, and subsequently activating them to produce an effective amount of at least one type of oxygen species on exposed carbon surfaces. The high purity carbon sorbent monoliths are vacuum-regenerable on a time scale of a few minutes. |
| FILED | Friday, July 03, 2020 |
| APPL NO | 16/920538 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/04 (20130101) B01D 2253/102 (20130101) B01D 2253/304 (20130101) B01D 2253/306 (20130101) B01D 2253/308 (20130101) B01D 2253/3425 (20130101) B01D 2257/70 (20130101) B01D 2257/406 (20130101) B01D 2259/4575 (20130101) B01D 2259/40083 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/20 (20130101) Original (OR) Class B01J 20/3007 (20130101) B01J 20/3078 (20130101) B01J 20/3085 (20130101) B01J 20/28042 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Non-metallic Elements; Compounds Thereof; C01B 32/318 (20170801) C01B 32/336 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083625 | Fang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX Corporation (Farmington, Connecticut); USA as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Xiaomei Fang (Glastonbury, Connecticut); Christopher J. Hertel (Wethersfield, Connecticut); John D. Riehl (Hebron, Connecticut); John W. Connell (Yorktown, Virginia); Frank L. Palmieri (Yorktown, Virginia); John W. Hopkins (Suffolk, Virginia) |
| ABSTRACT | Methods and systems for the laser surface treatment on stainless steel alloys and nickel alloys may include a computer may be programmed to set a laser path corresponding to a predetermined geometric pattern. A laser may be coupled to the computer and apply a pulsed laser beam to a contact surface of the substrate along the predefined geometric pattern. The pulsed laser beam may have a laser power between 0.1 W and 100 W, single pulse fluence 1 mJ/mm2 and 1025 mJ/mm2 and a laser speed between 25.4 cm/s and 127 cm/s. The laser may generate an open pore oxide layer on the contact surface of the substrate with a thickness of 0.1-1 μm, an open pore distance of 0.05-1 μm. The open pore oxide layer may have a topography corresponding to the predefined geometric pattern. The topography may contain open pore structures and promote adhesive bond performance. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/839753 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/359 (20151001) Original (OR) Class B23K 26/0622 (20151001) B23K 2103/05 (20180801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12083742 | Townsend et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sidus Space, Inc. (Merritt Island, Florida) |
| ASSIGNEE(S) | SIDUS SPACE, INC. (Merritt Island, Florida) |
| INVENTOR(S) | Ivan Townsend (Merritt Island, Florida); Robert Mueller (Merritt Island, Florida); Nathan Gelino (Merritt Island, Florida); Jonathan Smith (Merritt Island, Florida); Matthew Nugent (Merritt Island, Florida); Andrew Nick (Merritt Island, Florida); Jason Schuler (Merritt Island, Florida); Bradley Buckles (Merritt Island, Florida) |
| ABSTRACT | A three-dimensional print head apparatus comprising a hopper, a nozzle, a barrel, a heating system, a fume extraction system, a dry air purge system, and an agitator. The hopper may having a cavity and may have a lower aperture. The nozzle may have an upper aperture and may have a lower aperture. The heating system may be positioned along at least a portion of the barrel, which may defined a heated zone of the barrel. The dry air purge system may be in fluid communication with the hopper. The agitator may have at least one paddle. |
| FILED | Tuesday, September 26, 2023 |
| APPL NO | 18/474316 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 64/209 (20170801) Original (OR) Class B29C 64/329 (20170801) B29C 64/364 (20170801) B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084705 | Galazka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as Represented by the Administrator of the NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Jonathan Matthew Galazka (Mountain View, California); Asif Rahman (San Francisco, California); Samantha Therese Fleury (Littleton, Massachusetts) |
| ABSTRACT | Methylotrophic microorganisms, particularly methylotrophic yeasts and more particularly Pichia pastoris, which exhibit the ability to oxidize methane to methanol. Methods of making such microorganisms and DNA constructs for making such microorganisms. Such methylotrophic microorganisms are genetically transformed to exhibit the oxidizing activity of a soluble methane monooxygenase of a methanotrophic bacterium. Such transformed methylotrophic microorganisms contain at least three methane monooxygenase hydroxylase (MMOH) protein subunits of a methanotrophic bacterium: MMOH alpha, MMOH beta and MMOH gamma and a methane monooxygenase reductase (MMOR) of a methanotrophic bacterium. |
| FILED | Thursday, April 04, 2019 |
| APPL NO | 16/375824 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/16 (20130101) C12N 9/0071 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) Original (OR) Class Enzymes C12Y 114/13025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085430 | White et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts); Cornell University (Ithaca, New York); VANDERVALK NEESON INSTRUMENTS LTD. (Elizabethtown, Canada) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts); Cornell University (Ithaca, New York); Vandervalk Neeson Instruments Ltd. (Elizabethtown, Canada) |
| INVENTOR(S) | Robert White (Lexington, Massachusetts); Don Banfield (Ithaca, New York); Ian Neeson (Elizabethtown, Canada) |
| ABSTRACT | A method of determining flow speed in a low pressure environment. The method includes obtaining bi-directional acoustic data from a plurality of transducer pairs as a fluid moves relative to the plurality of transducer pairs. The method further includes measuring phase lags corresponding to the bi-directional acoustic data, and determining bi-directional flight times using the phase lags. Additionally, the method includes calculating a flow speed of the fluid corresponding to each transducer pair from the bi-directional flight times. The method includes correcting for at least one of temperature effects, pressure effects, and wake effects, using a system model. The method further includes generating a report including the flow speed of the fluid. |
| FILED | Thursday, January 07, 2021 |
| APPL NO | 17/144097 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/662 (20130101) Original (OR) Class G01F 1/667 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/58 (20130101) Meteorology G01W 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12085507 | Christensen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Lance E. Christensen (Baldwin Park, California); Kamjou Mansour (La Cañada Flintridge, California) |
| ABSTRACT | An in-situ sensor system that is configured to be placed inside of an oxygen mask for a pilot. The sensor system is readily placed in a position over the exhalation valve such that it can capture data from the exhaled air of the pilot. The sensor system has an optical sensor element that can capture data real time and feed the data to a control module that can subsequently be use to generate output data for the pilot and/or ground elements. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 17/645026 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0003 (20140204) A61M 2202/0208 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/61 (20130101) Original (OR) Class G01N 33/004 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12086434 | Liaghati |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Amir Leon Liaghati (Irvine, California) |
| ABSTRACT | Systems, apparatuses and methods provides for technology that identifies transmission priorities for a plurality of streamed data sources. The transmission priorities indicate a transmission order associated with the plurality of streamed data sources. The technology further generates a first permutation that is a first assignment of the plurality of streamed data sources to a plurality of transmitters for transmission, generates a first prediction of whether data from the plurality of streamed data sources will need to be stored prior to transmission based on the first permutation, the transmission priorities and bandwidths of the plurality of transmitters. The technology further generates a first allocation of storage space sizes that the plurality of streamed data sources will need based on the first permutation and the first prediction. |
| FILED | Friday, June 03, 2022 |
| APPL NO | 17/805315 |
| ART UNIT | 2138 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0604 (20130101) G06F 3/0631 (20130101) Original (OR) Class G06F 3/0656 (20130101) G06F 3/0679 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087803 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Todd J. Jones (Altadena, California); Shouleh Nikzad (Valencia, California) |
| ABSTRACT | A detector including a detector membrane comprising a semiconductor sensor and a readout circuit, the detector membrane having a thickness of 100 micrometers or less and a curved surface conformed to a curved focal plane of an optical system imaging electromagnetic radiation onto the curved surface; and a mount attached to a backside of the detector membrane. A maximum of the strain experienced by the detector membrane is reduced by distribution of the strain induced by formation of the curved surface across all of the curved surface of the detector membrane, thereby allowing an increased radius of curvature of the curved surface as compared to without the distribution. |
| FILED | Thursday, September 29, 2022 |
| APPL NO | 17/955679 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14683 (20130101) H01L 27/14875 (20130101) Original (OR) Class H01L 31/03926 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087867 | Siles Perez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Jose Vicente Siles Perez (Pasadena, California); Choonsup Lee (La Palma, California); Robert H. Lin (Chino, California); Alejandro Peralta (Pasadena, California) |
| ABSTRACT | A solid-state device chip including diodes (generating a higher or lower frequency output through frequency multiplication or mixing of the input frequency) and a novel on-chip diplexing design that allows combination of two or more multiplier or mixer structures operating at different frequency bands within the 50-5000 GHz range within a same chip and/or waveguide. The on-chip diplexing design consists of a single-substrate multiplier chip with two or more multiplying structures each one containing 2 or more Schottky diodes. The diodes in each structure are tuned to one portion of the target frequency band, resulting in the two or more structures working together as a whole as a large broadband multiplier or mixer. Thus, an increase in bandwidth from 10-15% (current state-of-the-art) to at least 40% is achieved. Depending on the target frequencies, each subset of diodes within the chip can be designed to work either as a doubler or a tripler. |
| FILED | Monday, November 09, 2020 |
| APPL NO | 17/093305 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/66 (20130101) H01L 29/872 (20130101) Original (OR) Class H01L 2223/6627 (20130101) H01L 2223/6688 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 19/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 12083565 | Quigley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Nicole Neff (North Potomac, Maryland); Jack Rowbottom (Swansea, Massachusetts) |
| ABSTRACT | A control system for controlling extraction of landfill gas from a landfill via a gas extraction system, the gas extraction system comprising well piping for coupling a plurality of wells to a gas output. The control system comprises a controller configured to: obtain a value indicating measured energy content of landfill gas collected at the gas output from the plurality of wells; determine whether the measured energy content is different from a target energy content; and in response to determining that the measured energy content is different from the target energy content: control a plurality of valves disposed in the well piping to change flow rates of landfill gas being extracted from at least some of the plurality of wells at least in part by changing degrees to which the plurality of valves are open. |
| FILED | Tuesday, October 04, 2022 |
| APPL NO | 17/959446 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/02 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/30 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084348 | Zeller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | H QUEST VANGUARD, INC. (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | H QUEST VANGUARD, INC. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Kurt W. Zeller (Pittsburgh, Pennsylvania); George L. Skoptsov (Pittsburgh, Pennsylvania); Evan T. Musselman (Pittsburgh, Pennsylvania) |
| ABSTRACT | Systems and methods for plasma based synthesis of graphitic materials. The system includes a plasma forming zone configured to generate a plasma from radio-frequency radiation, an interface element configured to transmit the plasma from the plasma forming zone to a reaction zone, and the reaction zone configured to receive the plasma. The reaction zone is further configured to receive feedstock material comprising a carbon containing species, and convert the feedstock material to a product comprising the graphitic materials in presence of the plasma. |
| FILED | Monday, June 13, 2022 |
| APPL NO | 17/806619 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/088 (20130101) B01J 19/126 (20130101) B01J 19/129 (20130101) B01J 2219/0875 (20130101) B01J 2219/0894 (20130101) B01J 2219/0896 (20130101) B01J 2219/0898 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) Original (OR) Class Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/30 (20130101) H05H 1/4622 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12084689 | Korman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INVIZYNE TECHNOLOGIES, INC. (Monrovia, California) |
| ASSIGNEE(S) | INVIZYNE TECHNOLOGIES, INC. (Monrovia, California) |
| INVENTOR(S) | Tyler P. Korman (Sierra Madre, California) |
| ABSTRACT | The present disclosure relates to recombinant prenyltransferase enzymes with increased thermostability and activity and the use of these enzymes in compositions and methods for biosynthesis involving prenylation reactions, including compositions and methods for the preparation of cannabinoids. |
| FILED | Thursday, September 22, 2022 |
| APPL NO | 17/934560 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1085 (20130101) Original (OR) Class C12N 15/52 (20130101) C12N 15/8243 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) Enzymes C12Y 203/01206 (20150701) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
12085549 — System and method for determining the sex and viability of poultry eggs prior to hatching
| US 12085549 | Rivers |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Adam R. Rivers (Gainesville, Florida) |
| ABSTRACT | Volatile organic chemicals emitted by a shell egg embryo are used to identify the fertility, viability, and sex of the shell egg embryo. Shortly after the egg is laid, the egg is isolated in a vapor-tight compartment so that a vapor containing volatile organic chemicals emitted by the shell egg embryo collect in the headspace of the compartment. The chemicals in the vapor are analyzed to construct a chemical profile of the shell egg embryo, and then the chemical profile of the shell egg embryo vapor is loaded into a previously developed model. Based on the data generated by the model, the shell egg is embryo is predicted to be an alive male, an alive female, an infertile egg, or an egg containing a dead embryo. |
| FILED | Monday, December 14, 2020 |
| APPL NO | 17/120656 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 43/00 (20130101) A01K 45/007 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/08 (20130101) Original (OR) Class G01N 33/6848 (20130101) G01N 2560/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP36100 | Lewers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Kimberly S. Lewers (Columbia, Maryland); John Enns (Hyattsville, Maryland) |
| ABSTRACT | This invention relates to a new and distinct cultivar of strawberry plant named ‘USDA Lumina’. The new early-season cultivar is primarily characterized by large, bright, glossy, sweet fruits resistant to anthracnose fruit rot. |
| FILED | Wednesday, September 06, 2023 |
| APPL NO | 18/242722 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/208 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 12083548 | Ray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The Government of the United States as represented by the Director, National Security Agency (Fort George G. Meade, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); The Government of the United States As Represented by the Director, National Security Agency (Ft. George G. Meade, Maryland) |
| INVENTOR(S) | Tyler Ray (Honolulu, Hawaii); Daniel R. Hines (Damascus, Maryland) |
| ABSTRACT | An aspect of the present disclosure provides a system for aerosol jet printing an aerosolized particle source configured to selectively provide aerosolized particles, a nozzle configured to deposit aerosolized particles on a substrate, an actuator configured to generate acoustic energy for migrating the particles, and a generator configured to selectively energize the actuator. The nozzle includes a proximal inlet configured for passage of aerosolized particles, a column configured to focus the aerosolized particles when vibrated by an actuator, and a distal opening configured for deposition of the particles on a substrate. |
| FILED | Monday, March 08, 2021 |
| APPL NO | 17/195300 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 17/06 (20130101) B05B 17/0638 (20130101) B05B 17/0646 (20130101) Original (OR) Class B05B 17/0676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12088569 | Cline et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States as represented by the Director, National Security Agency (Ft. George G. Meade, Maryland) |
| ASSIGNEE(S) | Government of the United States as represented by the National Security Agency (, None) |
| INVENTOR(S) | Joshua E. Cline (Edgewater, Maryland); Dan A. DeVries (Brooklyn, Maryland); William J. Layton (Sykesville, Maryland); Zachary Smith (Severn, Maryland); Brendan S. Surrusco (Highland, Maryland); Andrew H. White (Catonsville, Maryland); David F. Wiecek (Ft. George G. Meade, Maryland); Mitchell E. Buchman (Hanover, Maryland) |
| ABSTRACT | The present invention provides an encrypting device including an encryption unit and a communications unit. Paired encrypting devices allow for communication of trusted data between trusted devices over an untrusted network. Data received by the encryption unit is encrypted and provided with a connectionless header for delivery to the communications unit. Data received by the communications units is provided with a complex header for delivery to the paired encrypting device. The encrypting devices may be implemented in hardware or may be virtualized on a server or a plurality of severs. Arrangement of the encrypting devices in a hub-and-spoke topology allows for communication amongst a plurality of trusted devices. The encrypting devices can be used to covert commercially available equipment suitable for high assurance environments. |
| FILED | Monday, January 23, 2023 |
| APPL NO | 18/100312 |
| ART UNIT | 2499 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Electric Digital Data Processing G06F 21/602 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 45/74 (20130101) H04L 63/0272 (20130101) H04L 63/0471 (20130101) Original (OR) Class Wireless Communication Networks H04W 28/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 12084887 | Tartal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | William Albert Tartal (Baltimore, Maryland); Donald Eugene Irwin (Fredericksburg, Virginia) |
| ABSTRACT | A lock can include attack-resistant and/or weather-resistant features. Attack-resistant features can include a sacrificial link between a locking mechanism and an external keyway covering an exterior face of the locking mechanism. The sacrificial link can break during a torque attack on the lock such that the full force of the torque attack is not applied to the locking mechanism. Weather-resistant features can include drain openings in one or more housing components external to the locking mechanism to facilitate drainage of liquid matter from the lock before the liquid matter reaches the locking mechanism. |
| FILED | Monday, August 07, 2023 |
| APPL NO | 18/366557 |
| ART UNIT | 3675 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Household or Table Equipment A47G 29/1201 (20130101) A47G 29/1207 (20130101) Locks; Accessories Therefor; Handcuffs E05B 9/04 (20130101) E05B 15/1635 (20130101) E05B 17/0062 (20130101) Original (OR) Class E05B 17/142 (20130101) E05B 17/2003 (20130101) E05B 17/2084 (20130101) E05B 65/52 (20130101) Indexing Scheme Relating to Hinges or Other Suspension Devices for Doors, Windows or Wings and Devices for Moving Wings into Open or Closed Position, Checks for Wings and Wing Fittings Not Otherwise Provided For, Concerned With the Functioning of the Wing E05Y 2900/602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12086756 | Irwin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Wwashington, District of Columbia) |
| INVENTOR(S) | Donald Eugene Irwin (Fredericksburg, Virginia); Gabriel Michael Yessin (Vienna, Virginia); Joram Shenhar (Fairfax, Virginia); Joel Locknauth Dewnandan (Bladensburg, Maryland); Michael LeRoy Spears (Chantilly, Virginia); William Albert Tartal (Baltimore, Maryland) |
| ABSTRACT | Systems, devices and methods for storage, delivery, receipt, and/or other handling of an item in an electronically controllable storage receptacle are disclosed. The disclosure provides features for keyless access to the storage receptacle by use of user access information, such as a PIN or bar code. Further, features are disclosed for receiving and/or transmitting data related to the recipient and the item to facilitate the various handling actions of the item. |
| FILED | Tuesday, August 25, 2020 |
| APPL NO | 17/002442 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0836 (20130101) Original (OR) Class G06Q 10/0837 (20130101) G06Q 2220/00 (20130101) Coin-freed or Like Apparatus G07F 5/18 (20130101) G07F 9/001 (20200501) G07F 9/002 (20200501) G07F 17/13 (20200501) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 12083814 | Zlotnick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The United of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Joel Zlotnick (Arlington, Virginia); Jordan Brough (Leesburg, Virginia); Troy Eberhardt (Centreville, Virginia); Tyra McConnell (Knoxville, Maryland); Elizabeth Gil (Bristow, Virginia); Traci Moran (Rockville, Maryland) |
| ABSTRACT | Examples are directed toward anticounterfeit markings printed on a substrate. A method includes determining with a microprocessor running computer executable code non-transitorily stored on tangible computer readable media that: a first microprinting appears on a front side of the substrate as front side markings of first portions of a plurality of characters having dimensions in a micrometer range when viewed from the front side with reflected light, a second microprinting appears on a back side of the substrate as back side markings of second portions of the plurality of characters having dimensions in the micrometer range when viewed from the back side with reflected light, and the first microprinting and the second microprinting in combination appear as microprinting of whole characters of the plurality of characters when viewed with transmitted light. |
| FILED | Wednesday, August 09, 2023 |
| APPL NO | 18/232199 |
| ART UNIT | 2853 — Printing/Measuring and Testing |
| CURRENT CPC | Printing Machines or Presses B41F 1/16 (20130101) B41F 7/025 (20130101) B41F 31/008 (20130101) B41F 33/0036 (20130101) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 1/10 (20130101) B41M 1/14 (20130101) B41M 3/14 (20130101) B41M 3/148 (20130101) B41M 2205/34 (20130101) Indexing Scheme Relating to Printing, Lining Machines, Typewriters, and to Stamps B41P 2227/10 (20130101) Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/29 (20141001) Original (OR) Class B42D 25/333 (20141001) B42D 25/342 (20141001) B42D 25/351 (20141001) B42D 25/378 (20141001) B42D 25/405 (20141001) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 12084649 | Corgie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Stephane C. Corgie (Ithaca, New York); Xiaonan Duan (Ithaca, New York); Emmanuel Giannelis (Ithaca, New York); Daniel Aneshansley (Ithaca, New York); Larry P. Walker (Ithaca, New York) |
| ABSTRACT | A hierarchical catalyst composition comprising a continuous or particulate macroporous scaffold in which is incorporated mesoporous aggregates of magnetic nanoparticles, wherein an enzyme is embedded in mesopores of the mesoporous aggregates of magnetic nanoparticles. Methods for synthesizing the hierarchical catalyst composition are also described. Also described are processes that use the recoverable hierarchical catalyst composition for depolymerizing lignin, remediation of water contaminated with aromatic substances, polymerizing monomers by a free-radical mechanism, epoxidation of alkenes, halogenation of phenols, inhibiting growth and function of microorganisms in a solution, and carbon dioxide conversion to methanol. Further described are methods for increasing the space time yield and/or total turnover number of a liquid-phase chemical reaction that includes magnetic particles to facilitate the chemical reaction, the method comprising subjecting the chemical reaction to a plurality of magnetic fields of selected magnetic strength, relative position in the chemical reaction, and relative motion. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 17/587006 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/00 (20130101) B01J 19/12 (20130101) B01J 31/02 (20130101) B01J 31/003 (20130101) B01J 35/33 (20240101) B01J 35/56 (20240101) B01J 35/647 (20240101) B01J 35/651 (20240101) B01J 37/02 (20130101) B01J 2208/00805 (20130101) B01J 2219/0854 (20130101) B01J 2219/0862 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/484 (20130101) C02F 3/00 (20130101) C02F 3/342 (20130101) C02F 2101/327 (20130101) C02F 2209/006 (20130101) C02F 2303/04 (20130101) C02F 2305/08 (20130101) Acyclic or Carbocyclic Compounds C07C 1/12 (20130101) Heterocyclic Compounds C07D 301/22 (20130101) Compounds of Unknown Constitution C07G 1/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 14/00 (20130101) C08F 18/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/0006 (20130101) C12N 9/0061 (20130101) C12N 9/0065 (20130101) C12N 11/04 (20130101) Original (OR) Class C12N 11/08 (20130101) C12N 11/14 (20130101) C12N 11/091 (20200101) C12N 11/098 (20200101) C12N 13/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) C12P 7/22 (20130101) C12P 17/02 (20130101) Enzymes C12Y 101/03004 (20130101) C12Y 111/01 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/50 (20151101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 10/40 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 12084604 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Xuanhe Zhao (Allston, Massachusetts); Hyunwoo Yuk (Cambridge, Massachusetts); Heejung Roh (Cambridge, Massachusetts) |
| ABSTRACT | A dry shape memory adhesive material for adhering a target surface in the presence of fluid and for providing tunable mechanical contraction of an adhered surface. The dry shape memory adhesive material is pre-stretched and dried to provide an adhesive structure that implements a hydration-based shape memory mechanism to achieve both uniaxial and biaxial contractions of the adhered surface. According to preferred embodiments, the shape memory adhesive material includes a combination of one or more hydrophilic polymers or copolymers, one or more amine coupling group, and one or more cross linkers. |
| FILED | Tuesday, February 08, 2022 |
| APPL NO | 17/666642 |
| ART UNIT | 1788 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/25 (20180101) C09J 7/32 (20180101) Original (OR) Class C09J 2301/12 (20200801) C09J 2301/306 (20200801) C09J 2301/414 (20200801) C09J 2405/00 (20130101) C09J 2433/00 (20130101) C09J 2475/006 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/28 (20150115) Y10T 428/2852 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 12084680 | Lippmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Ethan Scott Lippmann (Nashville, Tennessee); Neha Sehgal (Philadelphia, Pennsylvania); Randolph Scott Ashton (Madison, Wisconsin) |
| ABSTRACT | Described herein are chemically defined, adherent culture protocols for generating functional motor neurons characteristic of diverse hindbrain and spinal cord regions, with high efficiency. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/149713 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0623 (20130101) Original (OR) Class C12N 2500/38 (20130101) C12N 2501/119 (20130101) C12N 2501/415 (20130101) C12N 2501/727 (20130101) C12N 2501/999 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 12088008 | Puchades et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rochester Institute of Technology (Rochester, New York); Eagle Technology, LLC (Wilmington, Delaware) |
| ASSIGNEE(S) | Rochester Institute of Technology (Rochester, New York); Eagle Technology, LLC (Wilmington, Delaware) |
| INVENTOR(S) | Ivan Puchades (Honeoye Falls, New York); Brian Landi (Rochester, New York); Ian D. Peterson (Rochester, New York); Rodney S. Sorrell (Melbourne, Florida); Stephen R. Landers (Satellite Beach, Florida); Andrew Bucossi (Rochester, New York) |
| ABSTRACT | An electromagnetic reflector composed of a non-knitted, non-metallic carbon-based material mesh, antenna system incorporating the reflector and method for fabrication are disclosed. |
| FILED | Thursday, February 18, 2021 |
| APPL NO | 17/179182 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 15/141 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 12084570 | Fox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | AMERICAN UNIVERSITY (Washington, District of Columbia) |
| ASSIGNEE(S) | AMERICAN UNIVERSITY (Washington, District of Columbia) |
| INVENTOR(S) | Douglas Fox (Reston, Virginia); Mauro Zammarano (Gaithersburg, Maryland); Whirang Cho (Gaithersburg, Maryland) |
| ABSTRACT | A flame retardant composition comprising chitosan or a modified chitosan, as well as a method for preparing a flame retardant comprising chitosan or a modified chitosan, is provided. Also provided are methods for making a flame retardant article using the described flame retardant composition. In various embodiments, the flame retardant composition is prepared by dissolution of chitosan or a modified chitosan by an aqueous acid, followed by evaporation of the water. In various embodiments, the flame retardant composition can further include at least one additional component selected from the group consisting of a polyol, flame retardant, nitrogen containing compound, carbonate containing compound, crosslinking agent, and combinations thereof. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/016855 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Polysaccharides; Derivatives Thereof C08B 37/003 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/07 (20130101) C08K 5/0025 (20130101) C08K 5/42 (20130101) C08K 5/092 (20130101) C08K 5/5353 (20130101) C08K 5/34926 (20130101) C08K 2003/265 (20130101) C08K 2003/2224 (20130101) C08K 2003/2227 (20130101) Compositions of Macromolecular Compounds C08L 5/08 (20130101) Original (OR) Class C08L 2201/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12087904 | Amatucci et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Glenn Amatucci (Peapack, New Jersey); Irene Plitz (Toms River, New Jersey); Linda Sung (Morris Plains, New Jersey); Anthony Ferrer (Red Lion, New Jersey) |
| ABSTRACT | An electrochemical cell is provided comprising a thin metal foil packaging made from at least one sheet of metal foil and having a perimeter extending around at least a portion of the electrochemical cell, as well as an electrochemical cell stack contained within the thin metal foil packaging, and a metal-to-metal welded seal around at least a portion of the perimeter of the thin metal foil packaging. The metal-to-metal welded seal is hermetic or nearly hermetic. Furthermore, the metal-to-metal welded seal is narrow, having a width of less than about 1 mm, and is less than about 5 mm away from the electrochemical cell stack. In some embodiments, the thin metal foil packaging functions not only as a hermetically or near hermetically sealed packaging, but also as either the negative or positive current collector, with one electrode of the cell bonded to the foil packaging. A method for making the foregoing electrochemical cell is also provided and involves using laser energy the metal-to-metal welded seal, wherein the laser energy is applied to the foil at high speed using a scanning laser. |
| FILED | Thursday, March 23, 2023 |
| APPL NO | 18/125550 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/133 (20130101) H01M 4/661 (20130101) H01M 10/058 (20130101) H01M 10/0525 (20130101) Original (OR) Class H01M 10/0585 (20130101) H01M 50/105 (20210101) H01M 50/119 (20210101) H01M 50/133 (20210101) H01M 50/545 (20210101) H01M 2220/20 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 10, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240910.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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