FedInvent™ Patents

Patent Details for Tuesday, September 24, 2024 

This page was updated on Thursday, September 26, 2024 at 04:05 AM GMT

Department of Health and Human Services (HHS) 

US 12096986 Chatzizisis
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) The Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) The Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Ioannis S. Chatzizisis (Omaha, Nebraska)
ABSTRACT In accordance with embodiments of this disclosure, a computational simulation platform comprises a computer-implemented method that includes: generating a mesh or meshless three-dimensional (3D) reconstruction of a vessel lumen and a surface of the vessel lumen based on invasive or non-invasive imaging; assigning material properties to the 3D reconstructed surface of the vessel lumen based on the invasive or non-invasive imaging; performing balloon pre-dilation, stenting and balloon post-dilation computational simulations with the 3D reconstructed vessel lumen and surface of the vessel lumen; and assessing stent and vessel morphometric and biomechanical measures based on the computational simulations.
FILED Friday, May 07, 2021
APPL NO 17/314338
ART UNIT 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 34/10 (20160201) Original (OR) Class
A61B 90/37 (20160201)
A61B 2034/102 (20160201)
A61B 2034/105 (20160201)
A61B 2090/378 (20160201)
A61B 2090/3762 (20160201)

Image Data Processing or Generation, in General
G06T 17/20 (20130101)
G06T 2210/41 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097015 Boamah et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Northwestern University (Evanston, Illinois);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  California Institute of Technology (Pasadena, California)
INVENTOR(S) Mavis D. Boamah (Evanston, Illinois);  Franz M. Geiger (Evanston, Illinois);  Thomas F. Miller, III (South Pasadena, California);  Jeongmin Kim (Pasadena, California)
ABSTRACT Energy harvesting devices and methods for converting the mechanical energy of a flowing ionic solution, such as rainwater or seawater, into electric energy are provided. The energy harvesting devices include an electric current generating device that includes a metal layer and an amphoteric metal oxide film disposed over a surface of the metal layer. By moving an electric double layer across the surface of the amphoteric metal oxide film, an electric current is generated in the metal layer.
FILED Tuesday, September 17, 2019
APPL NO 17/276684
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/026 (20130101) Original (OR) Class

Electric Machines Not Otherwise Provided for
H02N 1/08 (20130101)
H02N 11/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097037 Javitt et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York);  The Nathan S. Kline Institute for Psychiatric Research (Orangeburg, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York);  The Nathan S. Kline Institute for Psychiatric Research (Orangeburg, New York)
INVENTOR(S) Daniel Javitt (Fort Lee, New Jersey);  Antigona Martinez (New York, New York);  Yaakov Stern (New York, New York)
ABSTRACT An exemplary system, method, and computer-accessible medium for generating diagnostic data associated with a likelihood a patient(s) developing a mental disease(s) can be provided, which can include, for example, providing a visual patterns to the patient(s), receiving electroencephalogram (EEG) information from the patient(s) that can be based on the visual pattern(s); and generating the diagnostic data based on the EEG information.
FILED Wednesday, June 20, 2018
APPL NO 16/624452
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/374 (20210101)
A61B 5/378 (20210101) Original (OR) Class
A61B 5/4088 (20130101)
A61B 5/7257 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097055 Stayman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Joseph Webster Stayman (Baltimore, Maryland);  Jianan Gang (Baltimore, Maryland)
ABSTRACT In some implementations, a device may obtain scan information associated with scanning a section of a body that includes an object within tissue of the section. The device may determine a region of the section that is likely to be represented by an artifact in an image obtained using a first scanning type of a medical image device. The device may determine a plurality of scan patterns for scanning the region using a second scanning type. The device may determine, for the plurality of scan patterns, individual scan scores associated with scanning the region. The device may select, based on the individual scan scores, an optimal scan pattern from the plurality of scan patterns. The device may transmit the optimal scan pattern to the medical imaging device to permit the medical imaging device to scan the section to obtain optimized image data associated with the region.
FILED Friday, September 25, 2020
APPL NO 17/753726
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/032 (20130101) Original (OR) Class
A61B 6/54 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/20 (20180101)
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US 12097075 Alizad et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Azra Alizad (Rochester, Minnesota);  Mostafa Fatemi (Rochester, Minnesota);  Juanjuan Gu (Rochester, Minnesota)
ABSTRACT Ultrasound systems and methods are provided using mass characterization frequency methods that provide for predicting benign or malignant lesions, a response to treatment, tumor grading, and/or the expressions of immunohistochemical biomarkers, which are currently used for breast cancer classification and hormone therapy determination. The systems and methods are based on the shear wave parameter, mass characteristic frequency. The status of malignancy, treatment response, grade, and/or each immunohistochemical biomarker may be determined based on a corresponding mass characteristic frequency threshold.
FILED Friday, September 03, 2021
APPL NO 17/466073
ART UNIT 3797 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/085 (20130101)
A61B 8/485 (20130101)
A61B 8/0825 (20130101)
A61B 8/4488 (20130101)
A61B 8/5215 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097135 Raaz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
ASSIGNEE(S) Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Uwe Raaz (Leipzig, Germany);  Isabel Schellinger (Leipzig, Germany);  Joshua Spin (San Jose, California);  Philip Tsao (Los Altos, California)
ABSTRACT Methods, compositions, and devices for treating a vascular aneurysm, including an abdominal aortic aneurysm, are disclosed. In particular, the various embodiments relate to a method of treating an abdominal aortic aneurysm by increasing the mechanical stiffness of an aortic segment adjacent to the abdominal aortic aneurysm in a subject. The mechanical stiffness of the adjacent aortic segment may be increased, for example, by applying a surgical adhesive or intravascular stent. Such treatment reduces stress on the aortic wall and limits further growth of the abdominal aortic aneurysm.
FILED Tuesday, September 22, 2020
APPL NO 17/028048
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/00491 (20130101)
A61B 2017/00778 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/82 (20130101) Original (OR) Class
A61F 2/90 (20130101)
A61F 2002/823 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097196 Newman et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Amy Hauck Newman (Phoenix, Maryland);  Vivek Kumar (Baltimore, Maryland);  Anver Basha Shaik (Baltimore, Maryland)
ABSTRACT Disclosed herein are novel methods of treating pain in a patient in need thereof by providing to the patient a selective dopamine D3 receptor antagonist/partial agonist which when used with an opioid analgesic, can mitigate the development of opioid dependence, by preventing the need for dose escalation while either maintaining the opioid analgesic effect or providing analgesia with a lower dose of the opioid. In addition, the D3 antagonists/partial agonists described herein may be used to augment the effectiveness of current Medication Assisted Treatment regimens (e.g. methadone or buprenorphine) for the treatment of opioid use disorders.
FILED Friday, May 06, 2022
APPL NO 17/738301
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/485 (20130101)
A61K 31/496 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/36 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097213 Shay et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Regents of the University of Texas System (Austin, Texas)
ASSIGNEE(S) The Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S) Jerry Shay (Dallas, Texas);  Yang-Xin Fu (Dallas, Texas);  Ilgen Mender (Dallas, Texas);  Anli Zhang (Dallas, Texas)
ABSTRACT Disclosed herein are methods of treatments with a telomerase-mediated telomere-targeting drug, 6-thio-2′-deoxyguanosine (6-thio-dG), checkpoint inhibitors and/or radiation therapy for treating cancers. Leads to tumor regression in innate and adaptive immune-dependent manners in syngeneic and humanized mouse cancer models.
FILED Friday, March 12, 2021
APPL NO 17/200539
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/7076 (20130101) Original (OR) Class

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2818 (20130101)
C07K 16/2827 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097237 Briesewitz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Ohio State Innovation Foundation (Columbus, Ohio)
ASSIGNEE(S) Ohio State Innovation Foundation (Columbus, Ohio)
INVENTOR(S) Roger Briesewitz (Columbus, Ohio);  Dehua Pei (Columbus, Ohio);  Punit Upadhyaya (Columbus, Ohio)
ABSTRACT Disclosed herein are novel compounds that are Ras inhibitors. Also disclosed are compositions comprising the compounds and methods of using the compounds in treating various diseases.
FILED Wednesday, July 01, 2020
APPL NO 16/919031
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/01 (20130101)
A61K 38/00 (20130101)
A61K 38/012 (20130101) Original (OR) Class
A61K 38/12 (20130101)
A61K 39/3955 (20130101)
A61K 47/6811 (20170801)
A61K 47/6849 (20170801)
A61K 2039/585 (20130101)
A61K 2039/627 (20130101)
A61K 2300/00 (20130101)

Peptides
C07K 7/64 (20130101)
C07K 14/4703 (20130101)
C07K 16/2863 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097246 Labhasetwar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
ASSIGNEE(S) The Cleveland Clinic Foundation (Cleveland, Ohio)
INVENTOR(S) Vinod Labhasetwar (Cleveland, Ohio);  Hayder H. Jaffer (Cleveland, Ohio)
ABSTRACT The invention is directed to a method of treating a spinal cord injury, a neurodegenerative disease or a neuronal injury in an individual in need thereof comprising administering an effective amount of superoxide dismutase (SOD) and catalase to the individual, wherein the superoxide dismutase and the catalase are encapsulated in one or more nanoparticles that release the SOD and catalase upon administration. Another aspect of the invention is directed to compositions comprising superoxide dismutase (SOD) and catalase encapsulated in one or more nanoparticles.
FILED Wednesday, June 22, 2022
APPL NO 17/846130
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/19 (20130101)
A61K 9/5153 (20130101)
A61K 38/44 (20130101)
A61K 38/446 (20130101) Original (OR) Class

Enzymes
C12Y 111/01006 (20130101)
C12Y 115/01001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097258 Klein et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Bruce Steven Klein (Madison, Wisconsin);  Huafeng Wang (San Diego, California);  Marcel Wuethrich (Madison, Wisconsin);  Tristan Theodore Brandhorst (Madison, Wisconsin)
ABSTRACT A Dectin-2 ligand vaccine adjuvant and a method of making and using the Dectin-2 ligand vaccine adjuvant in a vaccine to immunize a patient are disclosed. Also discloses is a vaccine composition comprising a Bl-Eng2 antigen and methods of using the vaccine composition to immunize a subject against a fungal infection.
FILED Friday, February 26, 2021
APPL NO 17/186366
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/0002 (20130101)
A61K 39/39 (20130101) Original (OR) Class
A61K 2039/57 (20130101)
A61K 2039/55516 (20130101)
A61K 2039/55566 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097260 Overstreet
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) Sonoran Biosciences, Inc. (Tempe, Arizona)
ASSIGNEE(S) Sonoran Biosciences, Inc. (Tempe, Arizona)
INVENTOR(S) Derek J. Overstreet (Tempe, Arizona)
ABSTRACT A polymer composition can include an aqueous vehicle and a temperature-responsive degradable polymer having a polymer including a LCST-imparting unit and a lactone-bearing unit including a pendent lactone group. The number of LCST-imparting units is greater than the number of lactone-bearing units. The temperature-responsive degradable polymer has an initial lower critical solution temperature (LCST) of 37° C. or below. The polymer composition can have a pH lower than 7.
FILED Tuesday, November 16, 2021
APPL NO 17/528111
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle
A61J 1/2096 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 31/435 (20130101)
A61K 31/702 (20130101)
A61K 31/7036 (20130101)
A61K 47/32 (20130101) Original (OR) Class

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 5/19 (20130101)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 220/58 (20130101)
C08F 2800/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097264 Khaled et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida);  Sanford Burnham Prebys Medical Discovery Institute at Lake Nona (Orlando, Florida);  Memorial Sloan Kettering Cancer Center (New York, New York)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc., et al. (Orlando, Florida);  Sanford Burnham Prebys Medical Discovery Institute at Lake Nona (Orlando, Florida);  , Memorial Sloan Kettering Cancer Center (New York, New York)
INVENTOR(S) Annette Khaled (Orlando, Florida);  Jesus Manuel Perez Figueroa (Los Angeles, California);  Santimukul Santra (Pittsburg, Kansas);  Charalambos Kaittanis (Cambridge, Massachusetts);  Oscar Santiesteban (El Segundo, California);  Jan Grimm (Larchmont, New York);  Hampton Sessions (Orlando, Florida)
ABSTRACT Provided herein is a nanoparticle for drug delivery, wherein the nanoparticle comprises a hyperbranched polyester (HBPE) nanoparticle having a hydrophobic interior, polyglutamate folate ligands conjugated to the nanoparticle, and one or more PET detectable isotopes. Also provided herein are methods of using thereof.
FILED Monday, April 12, 2021
APPL NO 17/228286
ART UNIT 3991 — Central Reexamination Unit (Chemical)
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/08 (20130101)
A61K 38/10 (20130101)
A61K 45/06 (20130101)
A61K 47/6869 (20170801) Original (OR) Class
A61K 47/6935 (20170801)
A61K 51/1072 (20130101)
A61K 51/1244 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097268 Horsager et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) EOS Neuroscience, Inc. (San Francisco, California)
ASSIGNEE(S) EOS Neuroscience, Inc. (San Francisco, California)
INVENTOR(S) Alan Horsager (Los Angeles, California);  Andrew Smith (Santa Monica, California);  Benjamin C. Matteo (San Francisco, California)
ABSTRACT Provided herein are compositions and methods for the design of synthetic regulatory sequences and for subsequent modulation of neural pathways.
FILED Thursday, March 19, 2020
APPL NO 16/823905
ART UNIT 1638 — Central Reexamination Unit (Chemical)
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/0058 (20130101) Original (OR) Class

Peptides
C07K 14/4702 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2750/14043 (20130101)
C12N 2830/007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097290 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Liangfang Zhang (San Diego, California);  Che-Ming (Jack) Hu (San Diego, California);  Ronnie Hongbo Fang (Irvine, California);  Jonathan Copp (La Jolla, California)
ABSTRACT Provided are nanoparticles and methods of using and making thereof. The inventive nanoparticle comprises a) an inner core comprising a non-cellular material; and b) an outer surface comprising a cellular membrane derived from a cell or a membrane derived from a virus. Medicament delivery systems or pharmaceutical compositions comprising the inventive nanoparticles are also provided. Further provided are immunogenic compositions comprising the inventive nanoparticles, and methods of using the inventive immunogenic compositions for eliciting an immune response, and for treating or preventing diseases or condition, such as neoplasm or cancer, or disease or conditions associated with cell membrane inserting toxin. Vaccines comprising the immunogenic composition comprising the nanoparticles are also provided.
FILED Thursday, March 14, 2013
APPL NO 13/827906
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/148 (20130101) Original (OR) Class
A61K 39/39 (20130101)
A61K 39/085 (20130101)
A61K 39/001102 (20180801)
A61K 45/06 (20130101)
A61K 2039/80 (20180801)
A61K 2039/55555 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097291 Hassett et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado);  SOLIGENIX, INC. (Princeton, New Jersey)
ASSIGNEE(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado);  Soligenix, Inc. (Princeton, New Jersey)
INVENTOR(S) Kimberly Hassett (Medford, Massachusetts);  Pradyot Nandi (Denver, Colorado);  Robert N. Brey (Lakeside, Illinois);  John Carpenter (Littleton, Colorado);  Theodore Randolph (Niwot, Colorado)
ABSTRACT Compositions relating to thermostable vaccines and methods of preparing the same. Specifically, methods of preparing thermostable vaccines based on a recombinant ricin neurotoxin protein and uses of co-adjuvants to develop a composition capable of eliciting an immune response in a subject.
FILED Monday, May 10, 2021
APPL NO 17/316585
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/19 (20130101) Original (OR) Class
A61K 39/00 (20130101)
A61K 39/39 (20130101)
A61K 47/26 (20130101)
A61K 2039/55505 (20130101)
A61K 2039/55572 (20130101)

Technologies for Adaptation to Climate Change
Y02A 50/30 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097475 Ismagilov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Rustem F. Ismagilov (Chicago, Illinois);  Bo Zheng (Chicago, Illinois);  Cory John Gerdts (Chicago, Illinois)
ABSTRACT The present invention provides microfluidic technology enabling rapid and economical manipulation of reactions on the femtoliter to microliter scale.
FILED Friday, January 12, 2024
APPL NO 18/412395
ART UNIT 1796 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 25/314 (20220101)
B01F 33/3021 (20220101) Original (OR) Class

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101)
B01J 2219/0059 (20130101)
B01J 2219/00522 (20130101)
B01J 2219/00585 (20130101)
B01J 2219/00599 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/06 (20130101)
B01L 3/0293 (20130101)
B01L 3/527 (20130101)
B01L 3/502723 (20130101)
B01L 3/502746 (20130101)
B01L 3/502784 (20130101)
B01L 2200/0673 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0838 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/0406 (20130101)
B01L 2400/0409 (20130101)
B01L 2400/0415 (20130101)
B01L 2400/0433 (20130101)
B01L 2400/0487 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 7/00 (20130101)
C30B 29/58 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/38 (20130101)
G01N 35/08 (20130101)
G01N 2035/1034 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 7/0694 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 137/0318 (20150401)
Y10T 436/12 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097645 Repko et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Alexander James Repko (Pittsburgh, Pennsylvania);  Kacey Gribbin Marra (Canonsburg, Pennsylvania);  Benjamin Schilling (Pittsburgh, Pennsylvania)
ABSTRACT The presently disclosed subject matter relates to systems for making an implantable construct comprising a reservoir coupled to the at least one frame; a mandrel base coupled to the at least one frame; a mandrel coupled to the mandrel base; a first mechanism configured to be coupled to the at least one frame and configured to move the at least one frame along a first axis; a second mechanism configured to be coupled to the at least one frame and configured to rotate the least one mandrel base along a second axis between a first orientation and a second orientation; and a container configured to be coupled to the at least one frame and configured to receive the mandrel in the second orientation. The disclosed mechanisms can manually, semi-automatically, or automatically control the movements of the at least one frame, reservoir, mandrel, mandrel base, and container to produce the construct with a lumen. The presently disclosed subject matter also relates to methods for making the construct.
FILED Tuesday, September 14, 2021
APPL NO 17/474197
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 41/14 (20130101) Original (OR) Class
B29C 41/22 (20130101)
B29C 41/52 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2995/006 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/7532 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098117 Thiele et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) DUKE UNIVERSITY (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Dennis J. Thiele (Chapel Hill, North Carolina);  Bushu Dong (Durham, North Carolina);  Alexander M. Jaeger (Cambridge, Massachusetts);  Philip F. Hughes (Chapel Hill, North Carolina);  Timothy Haystead (Durham, North Carolina);  Jiyong Hong (Durham, North Carolina)
ABSTRACT This disclosure relates to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases related to Heat Shock Transcription Factor 1 (HSF1) activity and/or function. More particularly, this disclosure relates to methods of inhibiting HSF1 activity with these compounds and pharmaceutical compositions thereof, and methods of treating diseases associated with HSF1 activity and/or function, such as cancer.
FILED Wednesday, December 11, 2019
APPL NO 17/312858
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Acyclic or Carbocyclic Compounds
C07C 211/40 (20130101)
C07C 255/60 (20130101)
C07C 275/28 (20130101)
C07C 275/30 (20130101) Original (OR) Class
C07C 275/34 (20130101)
C07C 275/40 (20130101)
C07C 275/42 (20130101)
C07C 279/18 (20130101)
C07C 279/28 (20130101)
C07C 281/06 (20130101)
C07C 311/46 (20130101)
C07C 317/36 (20130101)
C07C 317/42 (20130101)

Heterocyclic Compounds
C07D 213/40 (20130101)
C07D 213/75 (20130101)
C07D 223/04 (20130101)
C07D 229/02 (20130101)
C07D 231/56 (20130101)
C07D 233/64 (20130101)
C07D 241/24 (20130101)
C07D 249/14 (20130101)
C07D 271/12 (20130101)
C07D 285/10 (20130101)
C07D 317/66 (20130101)
C07D 333/20 (20130101)
C07D 333/36 (20130101)
C07D 333/72 (20130101)
C07D 405/04 (20130101)
C07D 405/12 (20130101)
C07D 417/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098131 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) Jinkun Chen (Lexington, Massachusetts);  Qisheng Tu (Newton, Massachusetts);  Xingwen Wu (Boston, Massachusetts);  Gang Chen (Shanghai, China PRC);  Wei Qiu (Boston, Massachusetts)
ABSTRACT Disclosed herein are adiponectin receptor agonists and methods of using the same for the treatment of inflammation or bone loss in a subject.
FILED Wednesday, April 12, 2023
APPL NO 18/299266
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/08 (20180101)
A61P 29/00 (20180101)

Heterocyclic Compounds
C07D 211/58 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098153 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Yu Chen (Tampa, Florida);  Michael Sacco (Tampa, Florida);  James Leahy (Tampa, Florida);  Elena Bray (Tampa, Florida);  Xingmin Sun (Tampa, Florida);  Xiujun Zhang (Tampa, Florida)
ABSTRACT Disclosed herein are compounds that can prevent and treat C. difficile by inhibiting sporulation. Also disclosed herein are compositions and formulations comprising the compound disclosed herein. Methods of preventing and treating C. difficile comprising administering the compounds described herein are also disclosed.
FILED Wednesday, October 04, 2023
APPL NO 18/376525
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 45/06 (20130101)

Heterocyclic Compounds
C07D 471/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098169 Dong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts);  Paul Stenmark (Stockholm, Sweden)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Min Dong (Weatogue, Connecticut);  Paul Stenmark (Stockholm, Sweden);  Sicai Zhang (Boston, Massachusetts);  Andrew Doxey (Waterloo, Canada)
ABSTRACT Provided herein is a novel homolog of Clostridial botulinum neurotoxin (BoNT) identified in the bacterial species Enterococcus faecium (BoNT/EN). BoNT/EN variants and chimeric toxins comprising domains from BoNT/EN and other BoNTs are also provided. Further provided herein are methods of producing BoNT/EN and its use, e.g., in therapeutic applications.
FILED Friday, September 28, 2018
APPL NO 16/651720
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/33 (20130101)
C07K 14/315 (20130101) Original (OR) Class
C07K 2319/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098170 Sahay et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida);  RISE THERAPEUTICS, LLC (Rockville, Maryland)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida);  RISE THERAPEUTICS, LLC (Rockville, Maryland)
INVENTOR(S) Bikash Sahay (Gainesville, Florida);  Gary Fanger (Rockville, Maryland);  Jyoti Jha (Clarksburg, Maryland);  Christian Furlan Freguia (Germantown, Maryland)
ABSTRACT The current invention provides a recombinant bacterium, the recombinant bacterium being genetically modified to synthesize surface layer protein A (SlpA). Efficacious therapies for a subject suffering from an inflammation mediated disease are also provided. The methods of the current invention comprise administering to a subject in need thereof a therapeutically effective amount of the recombinant bacterium, for example L. lactis cells, or a therapeutically effective amount of the isolated SlpA. The recombinant bacteria cells or SlpA isolated from the recombinant bacteria can be in a pharmaceutical composition comprising a pharmaceutically acceptable carrier and/or excipient.
FILED Friday, June 10, 2022
APPL NO 18/568888
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/164 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 14/335 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098184 Sivaramakrishnan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Sivaraj Sivaramakrishnan (North Oaks, Minnesota);  Keehun Kim (Minneapolis, Minnesota)
ABSTRACT The systems and methods described herein include the use of Giant Plasma Membrane Vesicles (GPMVs) derived from cells expressing SPASM sensors (e.g., SPASM GPCR sensors). Herein provided are giant plasma membrane vesicle (GPMV) sensors containing a membrane-associated polypeptide, where the membrane-associated polypeptide contains a target G protein-coupled receptor (GPCR), a linker including an amino acid sequence flanked by a FRET donor and a FRET acceptor, and a receptor partner for the target GPCR, where the linker separates the target GPCR from the receptor partner. In another aspect, provided is a method for quantifying the intrinsic efficacy of a compound for a target GPCR. In another aspect, provided is a method for identifying a compound that interacts with a target GPCR.
FILED Tuesday, December 04, 2018
APPL NO 16/769852
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/723 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/68 (20130101)
G01N 33/542 (20130101)
G01N 33/566 (20130101)
G01N 2333/726 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098187 Ho et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) David D. Ho (Chappaqua, New York);  Yaoxing Huang (Brooklyn, New York);  Jian Yu (New Providence, New Jersey)
ABSTRACT In various embodiments, the present invention relates generally to using bispecific antibodies in the prevention and treatment of HIV.
FILED Thursday, December 20, 2018
APPL NO 16/770840
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/42 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)

Peptides
C07K 16/1063 (20130101) Original (OR) Class
C07K 16/2812 (20130101)
C07K 16/2866 (20130101)
C07K 2317/24 (20130101)
C07K 2317/31 (20130101)
C07K 2317/52 (20130101)
C07K 2317/66 (20130101)
C07K 2317/76 (20130101)
C07K 2317/94 (20130101)
C07K 2317/567 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098188 Bakaletz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S) Research Institute at Nationwide Children's Hospital (Columbus, Ohio)
ASSIGNEE(S) Research Institute at Nationwide Children's Hospital (Columbus, Ohio)
INVENTOR(S) Lauren O. Bakaletz (Hilliard, Ohio);  Steven D. Goodman (Hilliard, Ohio)
ABSTRACT This disclosure provides antibody fragments and isolated polypeptides comprising the antibody fragments that are useful as a therapeutic for those with an existing infection characterized by the formation of biofilms. Antibody fragments and isolated polypeptides comprising the antibody fragments can be administered to detect, treat, or prevent infection and/or remediate biofilms. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system and/or traditional antibiotics.
FILED Wednesday, January 03, 2018
APPL NO 16/475654
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 63/10 (20200101)
A01N 63/50 (20200101)
A01N 63/50 (20200101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 39/3955 (20130101)
A61K 45/06 (20130101)
A61K 2039/52 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Peptides
C07K 16/1203 (20130101) Original (OR) Class
C07K 16/1242 (20130101)
C07K 2317/24 (20130101)
C07K 2317/55 (20130101)
C07K 2317/76 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/56911 (20130101)
G01N 2333/285 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098190 Song et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania);  KIRA PHARMACEUTICALS (US) LLC (Arlington, Massachusetts)
ASSIGNEE(S) The Trustees of the University of Pennsylvania and (Pennsylvania, Pennsylvania);  Kira Pharmaceuticals (US) LLC (Arlington, Massachusetts)
INVENTOR(S) Wenchao Song (Bryn Mawr, Pennsylvania);  Takashi Miwa (Bala Cynwyd, Pennsylvania);  Damodar Gullipalli (Philadelphia, Pennsylvania);  Ping Tsui (North Potomac, Maryland);  Sayaka Sato (Philadelphia, Pennsylvania)
ABSTRACT This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody.
FILED Friday, September 06, 2019
APPL NO 17/273753
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 37/02 (20180101)

Peptides
C07K 16/18 (20130101) Original (OR) Class
C07K 2317/24 (20130101)
C07K 2317/94 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098193 Cukierman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Institute For Cancer Research (Philadelphia, Pennsylvania)
ASSIGNEE(S) Institute For Cancer Research (Philadelphia, Pennsylvania)
INVENTOR(S) Edna Cukierman (Philadelphia, Pennsylvania);  Ralph Francescone (Philadelphia, Pennsylvania);  Janusz Franco-Barraza (Philadelphia, Pennsylvania);  Kristopher Raghavan (Philadelphia, Pennsylvania)
ABSTRACT The present disclosure provides methods of inducing desmoplastic stroma to express a normal phenotype by detecting increased levels of NetG1 or NGL1 in tumor or in desmoplastic stroma isolated from a human subject, and/or detecting NetG1 in circulating extracellular vesicles, and/or detecting increased pFAK in the stroma, and treating the human subject with a therapeutic regimen; and by detecting NetG1 in a microvesicle isolated from a human subject, and/or treating the human subject with a therapeutic regimen.
FILED Tuesday, October 09, 2018
APPL NO 16/754877
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/217 (20130101)

Peptides
C07K 16/22 (20130101) Original (OR) Class
C07K 16/2818 (20130101)
C07K 16/2827 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57484 (20130101)
G01N 2800/7028 (20130101)
G01N 2800/7052 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098286 Choi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts);  Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts);  Northeastern University (Boston, Massachusetts)
INVENTOR(S) Hak Soo Choi (Needham, Massachusetts);  Jonghan Kim (Cambridge, Massachusetts);  Georges El Fakhri (Brookline, Massachusetts)
ABSTRACT Provided herein are compounds that are able to bind metal ions (e.g., free metal ions or metal ions bound to low affinity ligands) in a sample or subject. Also provided herein are methods of using the compounds for chelating metal ions and for the treatment of diseases associated with abnormal levels of metal ions. Methods of preparing the compounds and pharmaceutical compositions are also provided.
FILED Monday, May 15, 2023
APPL NO 18/197560
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 23/0025 (20130101)
C09B 23/0033 (20130101)
C09B 23/0041 (20130101)
C09B 23/0066 (20130101) Original (OR) Class
C09B 69/105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098353 McCain et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) University of Southern California (Los Angeles, California);  Children's Hospital of Los Angeles (Los Angeles, California)
INVENTOR(S) Megan McCain (Los Angeles, California);  Joycelyn Yip (Los Angeles, California);  Ching-Ling Lien (Los Angeles, California);  Michael Harrison (Los Angeles, California)
ABSTRACT Zebrafish are a powerful model for investigating cardiac repair due to their unique regenerative abilities, scalability, and compatibility with many genetic tools. However, characterizing the regeneration process in live adult zebrafish hearts has proved challenging because adult fish are opaque and explanted hearts in conventional culture conditions experience rapid declines in morphology and physiology. To overcome these limitations, we fabricated a fluidic device for culturing explanted adult zebrafish hearts with constant media perfusion that is also compatible with live imaging. Unlike hearts cultured in dishes for one week, the morphology and calcium activity of hearts cultured in the device for one week were largely similar to freshly explanted hearts. We also cultured injured hearts in the device and used live imaging techniques to continuously record the revascularization process over several days, demonstrating how our device enables unprecedented visual access to the multi-day process of adult zebrafish heart regeneration.
FILED Wednesday, March 22, 2023
APPL NO 18/124923
ART UNIT 1796 — Organic Chemistry
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 1/0247 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 2200/0684 (20130101)
B01L 2300/12 (20130101)
B01L 2300/087 (20130101)
B01L 2300/0877 (20130101)

Apparatus for Enzymology or Microbiology;
C12M 23/16 (20130101) Original (OR) Class
C12M 23/22 (20130101)
C12M 23/24 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098363 Bauer et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts);  UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
ASSIGNEE(S) THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts);  UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts)
INVENTOR(S) Daniel E. Bauer (Cambridge, Massachusetts);  Scot Wolfe (Boston, Massachusetts);  Mehmet Fatih Bolukbasi (Brighton, Massachusetts);  Benjamin Roscoe (Worcester, Massachusetts);  Pengpeng Liu (Worcester, Massachusetts);  Kevin Luk (Worcester, Massachusetts);  Yuxuan Wu (Boston, Massachusetts);  Jing Zeng (Boston, Massachusetts)
ABSTRACT Provided herein are methods and compositions for increasing fetal hemoglobin levels in a cell by disrupting BCL11A expression at the genomic level. Also provided herein are methods and compositions relating to the treatment of hemoglobinopathies by reinduction of fetal hemoglobin levels.
FILED Friday, July 20, 2018
APPL NO 16/964461
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/465 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/01 (20130101) Original (OR) Class
C12N 15/113 (20130101)
C12N 2310/20 (20170501)
C12N 2510/00 (20130101)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098366 Weiss et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Ron Weiss (Newton, Massachusetts);  Jin Huh (Watertown, Massachusetts)
ABSTRACT Disclosed herein is a subgenomic promoter library derived from alphavirus. Also provided herein are methods of using the subgenomic promoters to produce antibodies and other molecules.
FILED Friday, February 07, 2020
APPL NO 16/784962
ART UNIT 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 15/1072 (20130101)
C12N 15/1086 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098380 Yao
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
ASSIGNEE(S) THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts)
INVENTOR(S) Feng Yao (Southborough, Massachusetts)
ABSTRACT Provided herein are Vero cell lines that stably express Herpes Simplex Virus (HSV) ICP0 protein. These cells have the same morphology of Vero cells, exhibit stable expression of HSV ICP0 protein, and also efficiently complement replication of HSV ICP0 deficient virus for greater than 20, 30, or even 40 cell passages.
FILED Tuesday, June 05, 2018
APPL NO 16/619416
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/245 (20130101)

Peptides
C07K 14/005 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/16 (20130101)
C12N 5/0686 (20130101)
C12N 7/025 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2710/16622 (20130101)
C12N 2710/16643 (20130101)
C12N 2710/16652 (20130101)
C12N 2830/003 (20130101)
C12N 2830/60 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098381 Pederson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) University of Massachusetts (Boston, Massachusetts);  University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Thoru Pederson (Worcester, Massachusetts);  Scot Andrew Wolfe (Winchester, Massachusetts);  Hanhui Ma (Shrewsbury, Massachusetts);  Metewo Selase Kosi Enuameh (Gaithersburg, Maryland);  Nicola Anne Kearns (Somerville, Massachusetts);  Ryan Michael Jude Genga (Framingham, Massachusetts);  Rene Maehr (Newton, Massachusetts);  Shaojie Zhang (Oviedo, Florida);  Ardalan Naseri (Orlando, Florida);  Manuel Garber (Winchester, Massachusetts)
ABSTRACT The present disclosure relates to methods of and systems for modifying the transcriptional regulation of stem or progenitor cells to promote their differentiation or reprogramming of somatic cells. Further, the labeling and editing of human genomic loci in live cells with three orthogonal CRISPR/Cas9 components allow multicolor detection of genomic loci with high spatial resolution, which provides an avenue for barcoding elements of the human genome in the living state.
FILED Friday, March 12, 2021
APPL NO 17/200398
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0606 (20130101)
C12N 5/0696 (20130101)
C12N 9/22 (20130101)
C12N 15/63 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 15/907 (20130101)
C12N 2501/65 (20130101)
C12N 2501/70 (20130101)
C12N 2510/00 (20130101)
C12N 2740/15043 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6841 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098382 Perez et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S) University of Marylnd, College Park (College Park, Maryland)
INVENTOR(S) Daniel R. Perez (Olney, Maryland);  Hongjun Chen (Hyattsville, Maryland);  Yibin Cai (Hyattsville, Maryland);  Lindomar Jose Pena (College Park, Maryland);  Matthew Angel (Greenbelt, Maryland)
ABSTRACT Disclosed are compositions and methods comprising one or more recombinant influenza viruses. Recombinant influenza viruses with mutated polymerases and/or rearranged genomes are disclosed. Constructs comprising different influenza nucleic acid sequences are also provided. Methods of inducing protecting immunity with the recombinant influenza viruses are disclosed. Also disclosed are methods of plasmid-free production of influenza virus comprising amplicons comprising one or more of influenza genes.
FILED Friday, May 28, 2021
APPL NO 17/333904
ART UNIT 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/145 (20130101)
A61K 2039/70 (20130101)
A61K 2039/525 (20130101)
A61K 2039/543 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101) Original (OR) Class
C12N 2760/16122 (20130101)
C12N 2760/16134 (20130101)
C12N 2760/16143 (20130101)
C12N 2760/16151 (20130101)
C12N 2760/16162 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098385 Sheikh et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Farah Sheikh (La Jolla, California);  Jing Zhang (La Jolla, California)
ABSTRACT Disclosed herein are methods of treating arrhythmogenic right ventricular cardiomyopathy in a subject, comprising administering a gene therapy construct comprising a connexin 43 sequence, wherein as a result of the administration, connexin 43 levels in at least a portion of the heart are increased.
FILED Wednesday, April 29, 2020
APPL NO 16/862326
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/34 (20130101)
A61K 38/17 (20130101)
A61K 48/0058 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/00 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/861 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098390 Slukvin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Igor Slukvin (Verona, Wisconsin);  Akhilesh Kumar (Madison, Wisconsin)
ABSTRACT The present invention relates generally to methods and compositions useful for therapeutic vascular tissue engineering. In particular, the present invention provides methods for generating substantially pure populations of vasculogenic cells from human mesenchymal progenitors, and methods and compositions for clinical applications in the field of regenerative medicine.
FILED Monday, August 16, 2021
APPL NO 17/403202
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/28 (20130101)
A61K 35/34 (20130101)
A61K 35/44 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0661 (20130101) Original (OR) Class
C12N 2500/90 (20130101)
C12N 2501/11 (20130101)
C12N 2501/15 (20130101)
C12N 2501/115 (20130101)
C12N 2501/135 (20130101)
C12N 2501/165 (20130101)
C12N 2501/999 (20130101)
C12N 2506/02 (20130101)
C12N 2506/45 (20130101)
C12N 2506/1346 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098391 Gupta et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York)
ASSIGNEE(S) Albert Einstein College of Medicine (Bronx, New York)
INVENTOR(S) Sanjeev Gupta (Scarsdale, New York);  Sriram Bandi (Belleville, New Jersey)
ABSTRACT Methods are provided for producing differentiated cells from stem cells, including producing hepatocytes. Compositions thereof are also provided, as are methods of treating a liver disorder.
FILED Thursday, March 21, 2019
APPL NO 16/360228
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/407 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/067 (20130101) Original (OR) Class
C12N 5/0672 (20130101)
C12N 2500/84 (20130101)
C12N 2501/999 (20130101)
C12N 2502/14 (20130101)
C12N 2506/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098427 Muir et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
NIH Office of the Director (NIHOD)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Peter Muir (Madison, Wisconsin);  Susannah Sample (Madison, Wisconsin);  John Svaren (Madison, Wisconsin)
ABSTRACT Methods for diagnosing propensity to exhibit acquired peripheral neuropathy in dogs are described. The methods and kits test dogs for presence of a disease-associated genomic variant. Presence of the genomic variant indicates an increased likelihood of the dog developing an acquired peripheral neuropathy. This information can be used to guide preemptive clinical treatment of the animal for peripheral neuropathy and to choose dogs for selective breeding programs.
FILED Friday, September 16, 2022
APPL NO 17/946613
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101) Original (OR) Class
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098428 Deihimi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Institute For Cancer Research (Philadelphia, Pennsylvania)
ASSIGNEE(S) Institute For Cancer Research (Philadelphia, Pennsylvania)
INVENTOR(S) Safoora Deihimi (Philadelphia, Pennsylvania);  Michael Slifker (Philadelphia, Pennsylvania);  Wafik S. El-Deiry (Philadelphia, Pennsylvania)
ABSTRACT The present disclosure provides methods for identifying subjects having a cancer or tumor that may be susceptible to treatment with a therapeutic agent used to EGFR-related cancer an/or NTRK-related cancer.
FILED Monday, February 26, 2018
APPL NO 16/487272
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/506 (20130101)
A61K 31/517 (20130101)
A61K 31/5377 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/22 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101) Original (OR) Class
C12Q 2600/112 (20130101)
C12Q 2600/156 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098433 Jewett et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Michael Christopher Jewett (Evanston, Illinois);  Julius B. Lucks (Evanston, Illinois);  Adam D. Silverman (Chicago, Illinois);  Khalid K. Alam (Evanston, Illinois)
ABSTRACT Disclosed are methods, devices, kits, components, and compositions for detecting a target molecule in a test sample using a cell-free protein synthesis (CFPS) reaction. The methods, devices, kits, components, and compositions may be utilized for detecting target molecules which may include small molecules and/or metabolites of small molecules. The components and compositions used in the disclosed methods, devices, and kits may be dried or lyophilized and may be present or immobilized on a paper substrate, for example, as a paper test article.
FILED Monday, August 05, 2019
APPL NO 17/265785
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/485 (20130101)
C12Q 1/6897 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/184 (20240501)
G01N 33/521 (20130101)
G01N 33/1826 (20130101)
G01N 2430/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099012 Ly et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Mental Health (NIMH)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Victoria Ly (Santa Cruz, California);  Pierre Baudin (Santa Cruz, California);  Pattawong Pansodtee (Santa Cruz, California);  Erik Jung (Santa Cruz, California);  Robert Currie (Santa Cruz, California);  David Haussler (Santa Cruz, California);  Mircea Teodorescu (Santa Cruz, California)
ABSTRACT An imaging system includes an imaging device having a holder configured to hold a cell culture plate with a plurality of wells. The imaging device also includes an imaging assembly having a plurality of imaging units, each of which is configured to image one well of the plurality of wells. The imaging system also includes a storage platform in communication with the imaging device configured to receive a plurality of images from the imaging device. The system further includes a computer in communication with the imaging device and the storage platform. The computer is configured to control the imaging device and to display at least one image of the plurality of images.
FILED Friday, May 06, 2022
APPL NO 17/738251
ART UNIT 2485 — Recording and Compression
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 25/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101) Original (OR) Class
G01N 21/6486 (20130101)
G01N 2201/021 (20130101)
G01N 2201/062 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/365 (20130101)

Image Data Processing or Generation, in General
G06T 7/571 (20170101)
G06T 2207/10056 (20130101)
G06T 2207/10148 (20130101)
G06T 2207/30024 (20130101)
G06T 2207/30072 (20130101)

Pictorial Communication, e.g Television
H04N 5/265 (20130101)
H04N 23/62 (20230101)
H04N 23/66 (20230101)
H04N 23/90 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099152 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Ge Wang (Loudonville, New York);  Mengzhou Li (Troy, New York);  David S. Rundle (Butler, Pennsylvania)
ASSIGNEE(S) Rensselaer Polytechnic Institute (Troy, New York)
INVENTOR(S) Ge Wang (Loudonville, New York);  Mengzhou Li (Troy, New York);  David S. Rundle (Butler, Pennsylvania)
ABSTRACT A method for x-ray photon-counting data correction. The method includes generating, by a training data generation module, training input spectral projection data based, at least in part, on a reference spectral projection data. The training input spectral projection data includes at least one of a pulse pileup distortion, a charge splitting distortion, and/or noise. The method further includes training, by a training module, a data correction artificial neural network (ANN) based, at least in part, on training data. The data correction ANN includes a pulse pileup correction ANN, and a charge splitting correction ANN. The training data includes the training input spectral projection data and the reference spectral projection data.
FILED Friday, March 25, 2022
APPL NO 17/704520
ART UNIT 2884 — Optics
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 1/17 (20130101) Original (OR) Class
G01T 1/36 (20130101)
G01T 1/171 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 3/045 (20230101)
G06N 3/047 (20230101)
G06N 3/088 (20130101)
G06N 3/126 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12100480 Rivas et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Manuel A. Rivas (Palo Alto, California);  Matthew Woodward Aguirre (Stanford, California)
ABSTRACT Methods to determine an individual's propensity or risk for a trait and applications thereof are described. Generally, systems and methods utilize genetic data acquired from an individual to determine their propensity or risk for a set of components that contribute to a trait. Propensity or risk of a trait is determined by assessing propensity or risk for each component of a set of components and the weighted contribution of each component to the trait.
FILED Thursday, August 27, 2020
APPL NO 17/005241
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6883 (20130101)
C12Q 2600/156 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 20/20 (20190201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 12096747 Deng et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Z. Daniel Deng (Richland, Washington);  Jun Lu (Richland, Washington);  Huidong Li (Richland, Washington);  Jayson J. Martinez (Kennewick, Washington);  Mitchell J. Myjak (Richland, Washington)
ABSTRACT Organism monitoring devices and organism monitoring methods are described. According to one aspect, an organism monitoring device includes a housing configured to be physically associated with an organism to be monitored, an antenna, signal generation circuitry comprising an oscillator configured to generate an oscillation signal, and an output node configured to output the oscillation signal, impedance matching circuitry coupled with the housing, the antenna and the signal generation circuitry, and wherein the impedance matching circuitry is configured to match an impedance of the signal generation circuitry and an impedance of the antenna, and wherein the impedance matching circuitry is further configured to receive the oscillation signal and to provide the oscillation signal to the antenna, and wherein the antenna is configured to emit a wireless signal externally of the organism monitoring device as a result of the provision of the oscillation signal to the input of the antenna.
FILED Monday, March 01, 2021
APPL NO 17/189095
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 11/006 (20130101) Original (OR) Class

Antennas, i.e Radio Aerials
H01Q 1/50 (20130101)

Impedance Networks, e.g Resonant Circuits; Resonators
H03H 7/38 (20130101)
H03H 11/28 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/025 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097390 Sampayan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California);  Opcondys, Inc. (Manteca, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California);  Opcondys, Inc. (Manteca, California)
INVENTOR(S) Stephen E. Sampayan (Manteca, California);  Kristin Cortella Sampayan (Manteca, California);  George James Caporaso (East Quogue, California);  Yu-Jiuan Chen (Fremont, California);  Clifford C. Shang (Livermore, California)
ABSTRACT Methods, devices and systems for ultra-high dose radiotherapy are described that rely in-part on active switching control of a photoconductive switch when the accelerator is accelerating charged particles to produce output radiation at desired dose rates. One example method for producing output radiation in a flash radiotherapy system includes receiving, at a particle accelerator, a charged particle beam, where the particle accelerator system also includes a photoconductive switch coupled to the particle accelerator. The photoconductive switch can operate in a linear mode and includes a doped crystalline material that receives a voltage to establish an electric field across the crystalline material. The method includes producing a plurality of voltage pulses by the photoconductive switch in response to receiving light incident on the doped crystalline material, and accelerating the charged particles by the particle accelerator based on the plurality of voltage pulses to produce the output radiation beams for flash radiotherapy.
FILED Tuesday, June 06, 2023
APPL NO 18/329899
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1067 (20130101)
A61N 5/1071 (20130101) Original (OR) Class
A61N 5/1077 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098074 Wang et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) University of Maryland, College Park (College Park, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) YuHuang Wang (Laurel, Maryland);  Xiyuan Cheng (Greenbelt, Maryland);  Ayman Alibrahim (College Park, Maryland)
ABSTRACT A method of producing a carbon nanotube may include heating a convergent flow nozzle and a flow chamber of a carbon nanotube reactor, flowing a vaporized reactant stream through the nozzle and collecting a carbon nanotube product from an outlet of a heated flow chamber disposed downstream of the heated convergent flow nozzle. The vaporized reactant stream may include a carbon nanotube nucleation carbon source, a carbon nanotube growth carbon source, and a carbon nanotube catalyst precursor. The nozzle may have a nozzle contraction ratio of from 3:1 to 300:1.
FILED Friday, May 20, 2022
APPL NO 17/749696
ART UNIT 1759 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 32/162 (20170801) Original (OR) Class
C01B 2202/30 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/02 (20130101)
C01P 2002/82 (20130101)
C01P 2002/85 (20130101)
C01P 2002/88 (20130101)
C01P 2004/03 (20130101)
C01P 2004/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098079 Beach et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Starfire Energy (Denver, Colorado)
ASSIGNEE(S) STARFIRE ENERGY (Denver, Colorado)
INVENTOR(S) Joseph D. Beach (Aurora, Colorado);  Jonathan D. Kinter (Aurora, Colorado);  Adam W. Welch (Aurora, Colorado)
ABSTRACT A chemical reactor that combines a pressure vessel, heat exchanger, heater, and catalyst holder into a single device is disclosed. The chemical reactor described herein reduces the cost of the reactor and reduces its parasitic heat losses. The disclosed chemical reactor is suitable for use in ammonia (NH3) synthesis.
FILED Wednesday, February 16, 2022
APPL NO 17/672843
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 8/0278 (20130101)
B01J 8/0285 (20130101)
B01J 12/007 (20130101)
B01J 19/0013 (20130101)
B01J 2208/065 (20130101)
B01J 2219/00135 (20130101)

Ammonia; Cyanogen; Compounds Thereof
C01C 1/0411 (20130101)
C01C 1/0417 (20130101) Original (OR) Class

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 9/04 (20130101)
F28D 9/0093 (20130101)
F28D 2021/0022 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098171 O'Malley et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Michelle A. O'Malley (Santa Barbara, California);  Igor A. Podolsky (Goleta, California);  Susanna Seppala (Santa Barbara, California)
ABSTRACT The present invention provides for a hybrid sugar transporter having an altered sugar transporter activity and comprising at least a first transmembrane domain (TMD) from a first sugar transporter and a second TMD from a second sugar transporter, wherein the first sugar transporter and the second sugar transporter are heterologous to each other.
FILED Friday, December 10, 2021
APPL NO 17/548410
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 14/37 (20130101) Original (OR) Class
C07K 2319/03 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098186 Harmon et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Brooke Nicole Harmon (Livermore, California);  Le Thanh Mai Pham (Berkeley, California);  Yooli Kim Light (Pleasanton, California);  Christine Elizabeth Thatcher (Oakland, California);  Maxwell Stefan (Pleasanton, California)
ABSTRACT Provided herein are asymmetric biparatopic neutralizing nanobody-based antibodies which engage SARS-2 spike in at least two independent epitopes. Several biparatopic constructs showed synergy in neutralizing viral infection of cells. Data also showed that single biparatopic constructs are more effective than the combination of the parental monotopic constructs were at neutralization. The nanobodies that were identified in an initial screen of a large and highly diverse library bind to a single epitope that overlaps with the ACE2 binding site.
FILED Thursday, June 30, 2022
APPL NO 17/854735
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 16/10 (20130101) Original (OR) Class
C07K 2317/31 (20130101)
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098200 Harmon et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
INVENTOR(S) Brooke Nicole Harmon (Livermore, California);  Maxwell Stefan (Pleasanton, California);  Jennifer Schwedler (Livermore, California);  Christopher Sumner (Livermore, California);  Yooli Kim Light (Pleasanton, California);  Catherine Margaret Mageeney (Livermore, California)
ABSTRACT Provided herein are single domain antibodies (sdAbs) configured for passing the blood brain barrier in a human or mammal brain. Methods of using such sdAbs are also described herein, such as methods of binding to brain cells, binding with and transporting other sdAbs with beneficial functionalities, binding to and transporting biochemical or pharmaceutical species with beneficial functionalities, and treating, diagnosing, or prophylactically treating a disease, malignancy, or condition.
FILED Wednesday, October 12, 2022
APPL NO 17/964213
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)

Peptides
C07K 16/28 (20130101) Original (OR) Class
C07K 2317/565 (20130101)
C07K 2317/569 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/63 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098283 Liao et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Chen Liao (Westmont, Illinois);  Trevor L. Dzwiniel (Carol Stream, Illinois);  Kewel Liu (Aurora, Illinois)
ABSTRACT Described herein are borate salts useful as additives, binders, and electrolyte salts for solid state lithium ion batteries. In particular, the borate salts of Formula (I), Formula (II) and Formula (III) as described herein:
can be bound to an existing polymer to provide polymeric binders for ceramic solid state electrolytes that are themselves capable of ion transport independent of the ceramic.
FILED Friday, February 24, 2023
APPL NO 18/114055
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/04 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 79/08 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/37 (20130101)

Compositions of Macromolecular Compounds
C08L 85/04 (20130101) Original (OR) Class

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/622 (20130101)
H01M 10/0525 (20130101)
H01M 10/0565 (20130101)
H01M 2300/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098467 He et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Ting He (Idaho Falls, Idaho);  Dong Ding (Idaho Falls, Idaho);  Wei Wu (Idaho Falls, Idaho)
ABSTRACT A method of producing hydrogen gas comprises introducing gaseous water to an electrolysis cell comprising a positive electrode, a negative electrode, and a proton-conducting membrane between the positive electrode and the negative electrode. The proton-conducting membrane comprises an electrolyte material having an ionic conductivity greater than or equal to about 10−2 S/cm at one or more temperatures within a range of from about 150° C. to about 650° C. The gaseous water is decomposed using the electrolysis cell. A hydrogen gas production system and an electrolysis cell are also described.
FILED Wednesday, October 13, 2021
APPL NO 17/450810
ART UNIT 1759 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/04 (20130101) Original (OR) Class
C25B 1/042 (20210101)
C25B 1/044 (20210101)
C25B 9/23 (20210101)
C25B 9/73 (20210101)
C25B 11/047 (20210101)
C25B 13/05 (20210101)
C25B 13/07 (20210101)
C25B 15/021 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098469 Li et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Drexel University (Philadelphia, Pennsylvania)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  Drexel University (Philadelphia, Pennsylvania)
INVENTOR(S) Yawei Li (Shanxi, China PRC);  Kenneth Charles Neyerlin (Arvada, Colorado);  Joshua David Snyder (Sparks, Maryland)
ABSTRACT The present disclosure relates to a composition that includes a solid, a first layer of an ionic liquid including an anion and a cation, a second layer including an ionically conductive ionomer, and a catalyst including a metal positioned on the solid, where the ionic liquid forms a first layer on the solid, the first layer is positioned between the second layer and the solid, and the catalyst is positioned between the solid and the first layer.
FILED Tuesday, September 28, 2021
APPL NO 17/487108
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 11/053 (20210101) Original (OR) Class

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/86 (20130101)
H01M 4/88 (20130101)
H01M 8/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098475 Grotjohn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan);  Fraunhofer USA (Plymouth, Michigan)
ASSIGNEE(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan);  Fraunhofer USA (Plymouth, Michigan)
INVENTOR(S) Timothy A. Grotjohn (Okemos, Michigan);  Ramon Diaz (East Lansing, Michigan);  Aaron Hardy (East Lansing, Michigan)
ABSTRACT The disclosure relates to large area single crystal diamond (SCD) surfaces and substrates, and their methods of formation. Typical large area substrates can be at least about 25 mm, 50 mm, or 100 mm in diameter or square edge length, and suitable thicknesses can be about 100 μm to 1000 μm. The large area substrates have a high degree of crystallographic alignment. The large area substrates can be used in a variety of electronics and/or optics applications. Methods of forming the large area substrates generally include lateral and vertical growth of SCD on spaced apart and crystallographically aligned SCD seed substrates, with the individual SCD growth layers eventually merging to form a composite SCD layer of high quality and high crystallographic alignment. A diamond substrate holder can be used to crystallographically align the SCD seed substrates and reduce the effect of thermal stress on the formed SCD layers.
FILED Thursday, May 16, 2019
APPL NO 17/055943
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 25/04 (20130101)
C30B 25/08 (20130101)
C30B 25/12 (20130101)
C30B 25/16 (20130101)
C30B 25/20 (20130101)
C30B 25/025 (20130101) Original (OR) Class
C30B 29/04 (20130101)
C30B 29/68 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099048 Deng et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Z. Daniel Deng (Richland, Washington);  Yang Yang (Richland, Washington);  Jun Lu (Richland, Washington);  Huidong Li (Richland, Washington);  Jayson J. Martinez (Kennewick, Washington);  Brett D. Pflugrath (West Richland, Washington)
ABSTRACT Aquatic organism monitoring devices and aquatic organism monitoring methods are described. According to one aspect, a monitoring device includes a housing configured to be physically associated with an aquatic organism, environmental circuitry configured to generate a first output indicative of at least one environmental parameter of an environment of the organism, behavioral circuitry coupled with the housing and configured to generate a second output indicative of at least one behavioral parameter of the organism, physiological circuitry coupled with the housing and configured to generate a third output indicative of at least one physiological parameter of the organism, and a transmitter configured to transmit an acoustic signal externally of the housing, and wherein the acoustic signal includes information regarding one or more of the at least one environmental parameter, the at least one behavioral parameter, and the at least one physiological parameter.
FILED Wednesday, November 18, 2020
APPL NO 16/951251
ART UNIT 2896 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 11/006 (20130101)
A01K 61/90 (20170101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/186 (20130101) Original (OR) Class
G01N 33/1886 (20130101)

Technologies for Adaptation to Climate Change
Y02A 40/81 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099153 Goetz et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-BATTELLE, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Kathleen C. Goetz (Knoxville, Tennessee);  Mustafa S. Cetiner (Lexington, Massachusetts)
ABSTRACT A detector for generating an electrical current that is proportional to a flux of neutrons includes a neutron sensitive emitter, a conductive collector, an insulator between the neutron-sensitive emitter and the collector, an electrical connection to the neutron sensitive emitter, and an electrical connection to the conductive collector. The neutron sensitive emitter includes an emitter material with no more than 2 stable isotopes, and which upon impact by a neutron having an energy of from 100 keV to 1000 keV will generate electrons in proportion to the flux of neutrons in less than 10 minutes, and any generated electrons not generated in less than 10 minutes will be generated in no less than 30 days. A method of detecting neutrons generated by a nuclear reactor is also disclosed.
FILED Monday, October 25, 2021
APPL NO 17/510044
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Measurement of Nuclear or X-radiation
G01T 3/006 (20130101) Original (OR) Class

Nuclear Reactors
G21C 17/102 (20130101)
G21C 17/108 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099269 Chatterjee et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Bikramjit Chatterjee (Livermore, California);  Lars F. Voss (Livermore, California);  Clint Frye (Oakland, California)
ABSTRACT An optically addressable light valve comprises a first transparent conductor layer, a layer of liquid crystal, and a photoconductor comprising an ultrawide band gap (UWBG) semiconductor. The liquid crystal is between the first transparent conductor layer and the semiconductor photoconductor. The optically addressable light valve is configured to apply a voltage across the liquid crystal and the UWBG semiconductor. A second transparent conductor may be formed in the UWBG semiconductor in some configurations, and the voltage may be applied across the first and second transparent conductor.
FILED Friday, December 15, 2023
APPL NO 18/542455
ART UNIT 2871 — Optics
CURRENT CPC
Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/13439 (20130101)
G02F 1/133385 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099402 Baronne
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Micron Technology, Inc. (Boise, Idaho)
ASSIGNEE(S) Micron Technology, Inc. (Boise, Idaho)
INVENTOR(S) Christopher Baronne (Allen, Texas)
ABSTRACT Devices and techniques for parking threads in a barrel processor for managing hazard clearing are described herein. A barrel processor includes hazard management circuitry that is used to receive an indication of an instruction executing in a compute pipeline of the barrel processor, the instruction having encountered a hazard and unable to progress through the compute pipeline; store the indication of the instruction in a hazard memory; receive a signal indicating that the hazard has cleared; and cause the instruction to be rescheduled at the beginning of the compute pipeline in response to the signal.
FILED Monday, August 29, 2022
APPL NO 17/897926
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 9/3861 (20130101)
G06F 11/0721 (20130101)
G06F 11/0793 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099407 Sullivan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) NVIDIA Corp. (Santa Clara, California)
ASSIGNEE(S) NVIDIA CORP. (Santa Clara, California)
INVENTOR(S) Michael Sullivan (Austin, Texas);  Siva Kumar Sastry Hari (Sunnyvale, California);  Brian Matthew Zimmer (Mountain View, California);  Timothy Tsai (Santa Clara, California);  Stephen W. Keckler (Austin, Texas)
ABSTRACT An error reporting system utilizes a parity checker to receive data results from execution of an original instruction and a parity bit for the data. A decoder receives an error correcting code (ECC) for data resulting from execution of a shadow instruction of the original instruction, and data error correction is initiated on the original instruction result on condition of a mismatch between the parity bit and the original instruction result, and the decoder asserting a correctable error in the original instruction result.
FILED Thursday, May 05, 2022
APPL NO 17/737374
ART UNIT 2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 9/30029 (20130101)
G06F 9/30116 (20130101)
G06F 11/102 (20130101) Original (OR) Class
G06F 11/0772 (20130101)
G06F 11/1044 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099571 Yan et al.
FUNDED BY
Department of Energy (DOE)
Office of Electricity (DOE-OE)
APPLICANT(S) General Electric Company (Schenectady, New York)
ASSIGNEE(S) GE INFRASTRUCTURE TECHNOLOGY LLC (Greenville, South Carolina)
INVENTOR(S) Weizhong Yan (Clifton Park, New York);  Lalit Keshav Mestha (North Colonie, New York);  Daniel Francis Holzhauer (Burnt Hills, New York)
ABSTRACT Heterogeneous monitoring nodes may each generate a series of monitoring node values over time associated with operation of an industrial asset. An offline abnormal state detection model creation computer may receive the series of monitoring node values and perform a feature extraction process using a multi-modal, multi-disciplinary framework to generate an initial set of feature vectors. Then feature dimensionality reduction is performed to generate a selected feature vector subset. The model creation computer may derive digital models through a data-driven machine learning modeling method, based on input/output variables identified by domain experts or by learning from the data. The system may then automatically generate domain level features based on a difference between sensor measurements and digital model output. A decision boundary may then be automatically calculated and output for an abnormal state detection model based on the selected feature vector subset and the plurality of derived generated domain level features.
FILED Monday, May 21, 2018
APPL NO 15/984896
ART UNIT 2124 — AI & Simulation/Modeling
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 13/027 (20130101)
G05B 23/024 (20130101)
G05B 23/0254 (20130101)

Electric Digital Data Processing
G06F 18/213 (20230101) Original (OR) Class
G06F 2218/08 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099867 Puthoor et al.
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Advanced Micro Devices, Inc. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Sooraj Puthoor (Austin, Texas);  Joseph Gross (Austin, Texas);  Xulong Tang (State College, Pennsylvania);  Bradford Michael Beckmann (Redmond, Washington)
ABSTRACT Systems, apparatuses, and methods for implementing a multi-kernel wavefront scheduler are disclosed. A system includes at least a parallel processor coupled to one or more memories, wherein the parallel processor includes a command processor and a plurality of compute units. The command processor launches multiple kernels for execution on the compute units. Each compute unit includes a multi-level scheduler for scheduling wavefronts from multiple kernels for execution on its execution units. A first level scheduler creates scheduling groups by grouping together wavefronts based on the priority of their kernels. Accordingly, wavefronts from kernels with the same priority are grouped together in the same scheduling group by the first level scheduler. Next, the first level scheduler selects, from a plurality of scheduling groups, the highest priority scheduling group for execution. Then, a second level scheduler schedules wavefronts for execution from the scheduling group selected by the first level scheduler.
FILED Wednesday, May 30, 2018
APPL NO 15/993061
ART UNIT 2196 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/4881 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12100479 Vuyisich et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) BlueDot LLC (Bellevue, Washington);  TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) BLUEDOT, LLC (Bellevue, Washington);  TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico)
INVENTOR(S) Momchilo Vuyisich (Los Alamos, New Mexico);  Jason Gans (Los Alamos, New Mexico);  Niels Klitgord (Poway, California);  Po-E Li (Los Alamos, New Mexico);  Patrick Chain (Los Alamos, New Mexico)
ABSTRACT Provided are methods and systems for metagenomic analysis. Methods involve generating libraries and databases of taxonomic signatures informative of taxonomic information in a heterogeneous microbial sample. Methods also include identification of microorganisms and biochemical activities in the sample, including identification at a plurality of taxonomic levels.
FILED Thursday, March 01, 2018
APPL NO 16/490288
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1096 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6874 (20130101)

Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology
G16B 10/00 (20190201)
G16B 20/20 (20190201) Original (OR) Class
G16B 30/10 (20190201)
G16B 30/20 (20190201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12100520 Gates
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
Office of Science (DOE-SC)
Princeton Plasma Physics Laboratory (PPPL)
Federally Funded Research and Development Center (FFRDC)
Operated by Princeton University (PRINCETON) at Princeton, NJ
APPLICANT(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
ASSIGNEE(S) THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey)
INVENTOR(S) David Gates (Princeton, New Jersey)
ABSTRACT Disclosed herein is a stellarator comprising two sets of coils, namely a set of encircling coils which encircle the plasma axis, and a set of shaping coils which do not encircle any other coil or the plasma. In some embodiments, the encircling coils include a structural element to maintain their shape under magnetic forces. In some embodiments, the shaping coils are mounted onto one or more structural elements which, together with the shaping coils, constitute a field shaping unit. Also disclosed is a controller which may modify the electrical current flowing in one or more subsets of the coils in order to achieve target plasma parameters. Also disclosed is a method of designing a set of shaping coils by discretizing a surface dipole or current potential distribution.
FILED Thursday, January 18, 2024
APPL NO 18/415840
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Fusion Reactors
G21B 1/055 (20130101) Original (OR) Class

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 6/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12100521 Carter et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho);  University of Idaho (Moscow, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho);  University of Idaho (Moscow, Idaho)
INVENTOR(S) John P. Carter (Idaho Falls, Idaho);  Richard Christensen (Idaho Falls, Idaho)
ABSTRACT A flow control device configured to be positioned in a reactor core. The flow control device including a central shaft and at least one blade extending helically from the central shaft. A nuclear reactor and related systems and methods are also disclosed.
FILED Wednesday, September 28, 2022
APPL NO 17/936248
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Nuclear Reactors
G21C 15/12 (20130101) Original (OR) Class
G21C 19/28 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12100523 Callaway et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
APPLICANT(S) NuScale Power, LLC (Portland, Oregon)
ASSIGNEE(S) NuScale Power, LLC (Corvallis, Oregon)
INVENTOR(S) Allyson Callaway (Corvallis, Oregon);  Ben Bristol (Philomath, Oregon);  Kenneth Rooks (Corvallis, Oregon);  Larry Linik (Corvallis, Oregon)
ABSTRACT A nuclear power system includes a reactor vessel that includes a reactor core mounted therein. The reactor core includes nuclear fuel assemblies configured to generate a nuclear fission reaction. The nuclear power system further includes a chemical injection system configured to inject a chemical into the reactor vessel and remove the chemical from the reactor vessel, and a control system communicably coupled to the chemical injection system and configured to control a power output of the nuclear fission reaction. For example, the control system can determine that the power output is greater than an upper value of a range or less than a lower value of the range and, based on the determination, adjust an amount of the chemical injected into or removed from the reactor vessel by the chemical injection system to adjust the power output.
FILED Thursday, June 02, 2022
APPL NO 17/831083
ART UNIT 2628 — Selective Visual Display Systems
CURRENT CPC
Methods of Steam Generation; Steam Boilers
F22B 35/004 (20130101)

Nuclear Reactors
G21C 1/028 (20130101)
G21C 7/08 (20130101)
G21C 7/12 (20130101) Original (OR) Class
G21C 7/22 (20130101)
G21C 7/24 (20130101)
G21C 9/02 (20130101)
G21C 9/033 (20130101)
G21C 13/022 (20130101)

Nuclear Power Plant
G21D 1/006 (20130101)
G21D 3/02 (20130101)
G21D 3/14 (20130101)
G21D 3/16 (20130101)
G21D 3/18 (20130101)
G21D 5/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12100527 Blanton et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Paul S. Blanton (Aiken, South Carolina);  Zenghu Han (Woodridge, Illinois);  Yung Y. Liu (Hinsdale, Illinois);  Ronald B. Pope (Waynesboro, Pennsylvania);  James M. Shuler (Germantown, Maryland)
ABSTRACT The invention provides a containment structure, the containment structure comprising a vessel with an upwardly facing opening defining a periphery; a lid in rotatable and slidable communication with the periphery; and a plurality of rods contained within the lid and in slidable communication with the periphery. Also provided is a method for sealing and unsealing a containment vessel defining a body with a longitudinal axis and a lid, the method comprising simultaneously moving the lid parallel to the longitudinal axis and orthogonal to the longitudinal axis.
FILED Friday, February 18, 2022
APPL NO 17/675604
ART UNIT 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor
G21F 5/005 (20130101)
G21F 5/12 (20130101) Original (OR) Class
G21F 9/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12100560 Chowdhury et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Shajjad Chowdhury (Oak Ridge, Tennessee);  Raj Sahu (Mountain View, California);  Emre Gurpinar (Knoxville, Tennessee);  Burak Ozpineci (Oak Ridge, Tennessee)
ABSTRACT A capacitor packaging having a central termination and three or more capacitors (or groups of capacitors) arranged about the central termination. The electrical flow paths between the termination and the capacitors or groups of capacitors are of substantially the same length. The capacitors or groups of capacitors may be arranged in a generally circular pattern with the termination centered on the center. The termination may include first and second terminals. The capacitors may be mounted to a printed circuit board (“PCB”) with traces on opposite surfaces of the PCB providing electrical flow paths from the terminals to opposite legs of the capacitors. The capacitor packaging may include a primary PCB with a first circular arrangement of capacitors and a secondary PCB with a second circular arrangement of capacitors. The capacitors may be sandwiched between the PCBs with the second arrangement of capacitors disposed concentrically inwardly of the first arrangement.
FILED Thursday, May 12, 2022
APPL NO 17/742690
ART UNIT 2848 — Electrical Circuits and Systems
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 4/38 (20130101) Original (OR) Class
H01G 4/232 (20130101)
H01G 4/1245 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/162 (20130101)
H05K 2201/09227 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12100800 Ye et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Jianchao Ye (Tracy, California);  Jose Ali Espitia (Livermore, California);  John Miller (Walnut Creek, California);  Marissa Wood (Oakland, California)
ABSTRACT A product includes a solid state electrolyte particle coated with a coating consisting essentially of metal oxide. A method includes depositing a coating on a solid state electrolyte particle by atomic layer deposition. A method includes fabricating a product using a plurality of solid state electrolyte particles coated with a coating consisting essentially of metal oxide.
FILED Thursday, April 15, 2021
APPL NO 17/231886
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Compounds Containing Metals Not Covered by Subclasses C01D or C01F
C01G 25/006 (20130101)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2002/52 (20130101)
C01P 2002/72 (20130101)
C01P 2004/03 (20130101)
C01P 2004/84 (20130101)
C01P 2006/40 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 16/40 (20130101)
C23C 16/45555 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/62 (20130101)
H01M 10/0525 (20130101)
H01M 10/0562 (20130101) Original (OR) Class
H01M 2004/028 (20130101)
H01M 2300/0077 (20130101)
H01M 2300/0094 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12100966 Lethellier et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Wireless Advanced Vehicle Electrification, LLC (Salt Lake City, Utah)
ASSIGNEE(S) Wireless Advanced Vehicle Electrification, LLC (Salt Lake City, Utah)
INVENTOR(S) Patrice Lethellier (Salt Lake City, Utah);  Kelly Wardell (Stansbury Park, Utah);  Adeel Zaheer (West Valley, Utah)
ABSTRACT Described herein is a structure, the implementation of which may result in optimization of power transfer within a wireless power transfer pad. Such a structure comprises two planes in parallel that each comprise multiple windings. Additionally, the structure may include two magnetic structures that each pass through the centers of the multiple windings of one of the respective planes. In some embodiments, a magnetic structure may include a main section and two vertical sections. In some cases, the magnetic structure may further include at least one side section that connects with a vertical section.
FILED Wednesday, December 15, 2021
APPL NO 17/551743
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 50/005 (20200101) Original (OR) Class
H02J 50/12 (20160201)
H02J 50/40 (20160201)
H02J 50/90 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12101366 Palmer
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) TRIAD National Security, LLC. (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) David Palmer (Los Alamos, New Mexico)
ABSTRACT Techniques for framing data in various data transmission contexts are described. A data framing technique may include a transmitter sending a data stream including repeating bits in alternating forward and reverse order. A receiver of the data stream may fold the data stream, and correlate portions of the folded data stream for purposes of validating the data stream and/or identifying an ID in the data stream. In at least some instances, once the receiver validates the data stream, the receiver may accept payload accompanying the data stream.
FILED Monday, July 10, 2023
APPL NO 18/219962
ART UNIT 2465 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 7/24 (20130101)
H04B 7/216 (20130101)

Multiplex Communication
H04J 13/10 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/36 (20130101)
H04L 65/70 (20220501) Original (OR) Class
H04L 69/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12101367 Palmer
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) TRIAD National Security, LLC. (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) David Palmer (Los Alamos, New Mexico)
ABSTRACT A device includes a processor configured to generate a palindromic sequence associated with a unique identifier (ID) associated with the device, and provide the generated palindromic sequence to a transmitter, the palindromic sequence including forward order of bits, reverse order of bits and a spacer bit. The device further includes the transmitter configured to repeatedly transmit the generated palindromic.
FILED Monday, July 10, 2023
APPL NO 18/219976
ART UNIT 2465 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 7/24 (20130101)
H04B 7/216 (20130101)

Multiplex Communication
H04J 13/10 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/36 (20130101)
H04L 65/70 (20220501) Original (OR) Class
H04L 69/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12101398 Lukens et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Joseph M. Lukens (Knoxville, Tennessee);  Pavel Lougovski (Knoxville, Tennessee)
ABSTRACT Methods of quantum key distribution include receiving a frequency bin photon at a location, selecting a frequency bin photon quantum key distribution measurement basis, with a quantum frequency processor, performing a measurement basis transformation on the received frequency bin photon so that the frequency bin photon is measurable in the selected frequency bin photon quantum key distribution measurement basis, and detecting the frequency bin photon in the selected quantum key distribution measurement basis and assigning a quantum key distribution key value based on the detection to a portion of a quantum key distribution key. Apparatus and methods for encoding, decoding, transmitting, and receiving frequency bin photons are disclosed.
FILED Thursday, June 29, 2023
APPL NO 18/216450
ART UNIT 2435 — Cryptography and Security
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/00 (20190101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/0858 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12101870 Kobernik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Energy (DOE)
APPLICANT(S) SHINE Technologies, LLC (Janesville, Wisconsin)
ASSIGNEE(S) SHINE Technologies, LLC (Janesville, Wisconsin)
INVENTOR(S) Arne Kobernik (Monona, Wisconsin);  Carl Sherven (Monona, Wisconsin);  Casey Lamers (Monona, Wisconsin);  Chris Seyfert (Monona, Wisconsin);  Evan Sengbusch (Monona, Wisconsin);  Gabriel Becerra (Monona, Wisconsin);  Jin Lee (Monona, Wisconsin);  Logan Campbell (Monona, Wisconsin);  Mark Thomas (Monona, Wisconsin);  Michael Taylor (Monona, Wisconsin);  Preston Barrows (Monona, Wisconsin);  Ross Radel (Monona, Wisconsin);  Tye Gribb (Monona, Wisconsin)
ABSTRACT Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes.
FILED Monday, January 09, 2023
APPL NO 18/094724
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 37/08 (20130101)
H01J 37/32082 (20130101)
H01J 41/04 (20130101)
H01J 41/14 (20130101)

Spark Gaps; Overvoltage Arresters Using Spark Gaps; Sparking Plugs; Corona Devices; Generating Ions to be Introduced into Non-enclosed Gases
H01T 23/00 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 31/26 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/46 (20130101)
H05H 1/54 (20130101)
H05H 1/4622 (20210501)
H05H 3/06 (20130101)
H05H 5/04 (20130101)
H05H 6/00 (20130101)
H05H 7/22 (20130101) Original (OR) Class
H05H 9/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12101948 Hammond et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  SolarWindow Technologies, Inc. (Scottsdale, Arizona)
ASSIGNEE(S) Alliance for Sustainable Energy, LLC (Golden, Colorado);  SolarWindow Technologies, Inc. (Scottsdale, Arizona)
INVENTOR(S) Scott R. Hammond (Wheat Ridge, Colorado);  Marinus Franciscus Antonius Maria van Hest (Golden, Colorado)
ABSTRACT Systems and methods for organic semiconductor devices with sputtered contact layers are provided. In one embodiment, an organic semiconductor device comprises: a first contact layer comprising a first sputter-deposited transparent conducting oxide; an electron transport layer interfacing with the first contact layer; a second contact layer comprising a second sputter-deposited transparent conducting oxide; a hole transport layer interfacing with the second contact layer; and an organic semiconductor active layer having a first side facing the electron transport layer and an opposing second side facing the hole transport layer; wherein either the electron transport layer or the hole transport layer comprises a buffering transport layer.
FILED Thursday, July 13, 2023
APPL NO 18/351880
ART UNIT 2818 — Semiconductors/Memory
CURRENT CPC
Organic electric solid-state devices
H10K 30/82 (20230201) Original (OR) Class
H10K 50/11 (20230201)
H10K 50/15 (20230201)
H10K 50/16 (20230201)
H10K 50/816 (20230201)
H10K 50/828 (20230201)
H10K 71/16 (20230201)
H10K 71/60 (20230201)
H10K 2102/101 (20230201)
H10K 2102/103 (20230201)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/549 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12102005 Schwede et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Spark Thermionics, Inc. (Berkeley, California)
ASSIGNEE(S) Spark Thermionics, Inc. (Berkeley, California)
INVENTOR(S) Jared William Schwede (Berkeley, California);  Lucas Heinrich Hess (Berkeley, California)
ABSTRACT A thermionic energy converter, preferably including an anode and a cathode. An anode of a thermionic energy converter, preferably including an n-type semiconductor, one or more supplemental layers, and an electrical contact. A method for work function reduction and/or thermionic energy conversion, preferably including inputting thermal energy to a thermionic energy converter, illuminating an anode of the thermionic energy converter, thereby preferably reducing a work function of the anode, and extracting electrical power from the system.
FILED Wednesday, November 23, 2022
APPL NO 17/993195
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 45/00 (20130101)

Electric solid-state devices not otherwise provided for
H10N 10/13 (20230201) Original (OR) Class
H10N 10/851 (20230201)
H10N 10/853 (20230201)
H10N 10/855 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP36135 McMahon et al.
FUNDED BY
Department of Energy (DOE)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Bernard G. McMahon (Coon Rapids, Minnesota);  William Berguson (Duluth, Minnesota)
ABSTRACT The invention is a new and distinct variety of male Populus tree named ‘NextGen’ that is characterized by its superior to above average field growth performance, its excellent to above average rooting rate, its disease resistance to foliar rusts (Melampsora sp.), leaf spots (Marssonina sp.) and stem cankers (Septoria sp.), its vigorous vegetative growth and production in nursery stoolbeds, its cold hardiness for overwintering and surviving in Minnesota with no frost damage, its wide-spread superior growth performance in many test locations (ie: MN, MI, WI, IA, IN, NY, etc); able to be considered “geo-robust” after years of testing, its replicated growth testing and evidence of promising performance and evaluation in phytoremediation research testing and applications, and its male flowers that do not produce seeds.
FILED Wednesday, November 22, 2023
APPL NO 18/517841
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/218
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 12096999 Frederick et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Telemedicine and Advanced Technology Research Center (TATRC)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Tom Frederick (Lincoln, Nebraska);  Eric Markvicka (Brush, Colorado);  Shane Farritor (Lincoln, Nebraska);  Dmitry Oleynikov (Omaha, Nebraska)
ABSTRACT The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices.
FILED Thursday, August 04, 2022
APPL NO 17/880823
ART UNIT 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/14 (20130101)
A61B 18/082 (20130101)
A61B 18/1445 (20130101)
A61B 34/30 (20160201) Original (OR) Class
A61B 2017/00398 (20130101)
A61B 2017/00407 (20130101)
A61B 2017/00477 (20130101)
A61B 2018/00595 (20130101)
A61B 2018/1253 (20130101)
A61B 2018/1422 (20130101)
A61B 2034/305 (20160201)
A61B 2217/005 (20130101)
A61B 2217/007 (20130101)
A61B 2218/002 (20130101)
A61B 2218/007 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/046 (20130101)
B25J 9/0087 (20130101)
B25J 9/102 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097015 Boamah et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Northwestern University (Evanston, Illinois);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  California Institute of Technology (Pasadena, California)
INVENTOR(S) Mavis D. Boamah (Evanston, Illinois);  Franz M. Geiger (Evanston, Illinois);  Thomas F. Miller, III (South Pasadena, California);  Jeongmin Kim (Pasadena, California)
ABSTRACT Energy harvesting devices and methods for converting the mechanical energy of a flowing ionic solution, such as rainwater or seawater, into electric energy are provided. The energy harvesting devices include an electric current generating device that includes a metal layer and an amphoteric metal oxide film disposed over a surface of the metal layer. By moving an electric double layer across the surface of the amphoteric metal oxide film, an electric current is generated in the metal layer.
FILED Tuesday, September 17, 2019
APPL NO 17/276684
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/026 (20130101) Original (OR) Class

Electric Machines Not Otherwise Provided for
H02N 1/08 (20130101)
H02N 11/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097029 Shanechi
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) University of Southern California (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Maryam Shanechi (Los Angeles, California)
ABSTRACT A method for decoding mood or other neuropsychiatric states from large-scale brain activity includes receiving, by a processor, large-scale brain activity signals from an electrode assembly coupled to a subject. The method includes continuously and automatically decoding a neuropsychiatric state of the subject from the large-scale brain activity signals received from a predictive network subset of brain sites coupled to the electrode assembly, contemporaneously with the receiving. The method includes providing a signal indicative of the neuropsychiatric state. A method for adaptive tracking of large-scale brain network activity includes characterizing, by one or more computers, a time-variant linear state-space model predictive of a brain state, at least in part by updating estimates of time-varying covariance matrices at time steps. The method includes tracking large-scale brain network activity in a subject using an electrode array and continuously and automatically estimating the subject's brain state contemporaneously with the characterizing and tracking.
FILED Tuesday, July 10, 2018
APPL NO 16/031925
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/16 (20130101)
A61B 5/165 (20130101) Original (OR) Class
A61B 5/316 (20210101)
A61B 5/369 (20210101)
A61B 5/4803 (20130101)
A61B 5/7267 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097246 Labhasetwar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio)
ASSIGNEE(S) The Cleveland Clinic Foundation (Cleveland, Ohio)
INVENTOR(S) Vinod Labhasetwar (Cleveland, Ohio);  Hayder H. Jaffer (Cleveland, Ohio)
ABSTRACT The invention is directed to a method of treating a spinal cord injury, a neurodegenerative disease or a neuronal injury in an individual in need thereof comprising administering an effective amount of superoxide dismutase (SOD) and catalase to the individual, wherein the superoxide dismutase and the catalase are encapsulated in one or more nanoparticles that release the SOD and catalase upon administration. Another aspect of the invention is directed to compositions comprising superoxide dismutase (SOD) and catalase encapsulated in one or more nanoparticles.
FILED Wednesday, June 22, 2022
APPL NO 17/846130
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/19 (20130101)
A61K 9/5153 (20130101)
A61K 38/44 (20130101)
A61K 38/446 (20130101) Original (OR) Class

Enzymes
C12Y 111/01006 (20130101)
C12Y 115/01001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097269 Kundra et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) Vikas Kundra (Missouri City, Texas);  James A. Bankson (Pearland, Texas);  Ananth Annapragada (Manvel, Texas);  Ketan B. Ghaghada (Houston, Texas);  Murali K. Ravoori (Pearland, Texas)
ASSIGNEE(S)
INVENTOR(S) Vikas Kundra (Missouri City, Texas);  James A. Bankson (Pearland, Texas);  Ananth Annapragada (Manvel, Texas);  Ketan B. Ghaghada (Houston, Texas);  Murali K. Ravoori (Pearland, Texas)
ABSTRACT Provided herein are nanoparticle-based gadolinium (Gd) agents which may be used, e.g., in T1-weighted MR imaging (MRI). In various embodiments, dual-Gd liposomal agents are provided which contain both core-encapsulated Gd as well as surface-conjugated Gd. In various embodiments, these agents were observed to deliver a higher concentrations of Gd and result in substantial improvements in signal to noise ratios and contrast to noise ratios. Also provided are methods for in vivo imaging and/or treating diseases such as cancer or tumor in a subject.
FILED Thursday, October 27, 2011
APPL NO 13/283272
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/704 (20130101)
A61K 49/14 (20130101)
A61K 49/1812 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097304 Alghazali et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
INVENTOR(S) Karrer M. Alghazali (Little Rock, Arkansas);  Zeid A. Nima (Little Rock, Arkansas);  Alexandru S. Biris (Little Rock, Arkansas)
ABSTRACT A method for forming a biocompatible structure includes the steps of forming a layered structure having alternatively disposed first layers and second layers, where the first layers includes at least one polymer and first particles, and the second layers includes second particles; and treating the layered structure with a washing solvent to form the biocompatible structure, where the first particles are solvable in the washing solvent.
FILED Wednesday, May 10, 2017
APPL NO 15/591728
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/12 (20130101)
A61L 27/14 (20130101)
A61L 27/18 (20130101)
A61L 27/18 (20130101)
A61L 27/20 (20130101)
A61L 27/38 (20130101)
A61L 27/54 (20130101)
A61L 27/56 (20130101)
A61L 27/58 (20130101)
A61L 27/3608 (20130101)
A61L 27/3695 (20130101) Original (OR) Class
A61L 2300/256 (20130101)
A61L 2300/258 (20130101)
A61L 2300/414 (20130101)
A61L 2400/08 (20130101)
A61L 2400/12 (20130101)
A61L 2430/02 (20130101)

Compositions of Macromolecular Compounds
C08L 67/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097500 Xie et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) Rutgers, The State University of New Jersey (New Brunswick, New Jersey);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Pengfei Xie (Piscataway, New Jersey);  Mehdi Javanmard (West Windsor, New Jersey);  Mark George Allen (Philadelphia, Pennsylvania);  Wen Shen (Arlington, Texas);  Naixin Song (Philadelphia, Pennsylvania)
ABSTRACT A sensor for detecting a target analyte in a sample includes a pair of conducting electrodes that are separated by a gap. An insulator is disposed in the gap between the electrodes. Plural wells are defined by one of the electrodes and the insulator, to expose the other of the electrodes. The wells are configured to receive a sample including a target analyte. The target analyte, when present in the sample received in the wells, modulates an impedance between the electrodes. The modulated impedance, which is measurable with an applied electrical voltage, is indicative of the concentration of the target analyte in the sample. The wells can include antibodies immobilized inside the wells, to bind the target analyte, which can be a cytokine. Also provided are a method for label-free sensing of a target analyte in a sample, and a transcutaneous impedance sensor for label-free, in-situ biomarker detection.
FILED Friday, April 17, 2020
APPL NO 16/852113
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/5085 (20130101) Original (OR) Class
B01L 2300/123 (20130101)
B01L 2300/0636 (20130101)
B01L 2300/0645 (20130101)
B01L 2300/0893 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/02 (20130101)
G01N 33/6863 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097567 Herrington et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Voxel Innovations, Inc. (Raleigh, North Carolina)
ASSIGNEE(S) Voxel Innovations, Inc. (Raleigh, North Carolina)
INVENTOR(S) Daniel Herrington (Raleigh, North Carolina);  Eric Rountree (Raleigh, North Carolina)
ABSTRACT A technique of removing material from metal parts referred to as OPECM and a corresponding OPECM processing machine are disclosed. A tool electrode is manufactured for removing material from a target workpiece, and the workpiece and tool electrode are fixed into a processing machine that imparts an oscillatory motion path or profile and applies a voltage through a flowing electrolyte solution. The disclosed technique and processing machine removes material from the surface of the target workpiece through proximal surface dissolution as the workpiece and tool electrode are brought within proximity of one another.
FILED Thursday, December 30, 2021
APPL NO 17/565817
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/62 (20210101)

Working of Metal by the Action of a High Concentration of Electric Current on a Workpiece Using an Electrode Which Takes the Place of a Tool; Such Working Combined With Other Forms of Working of Metal
B23H 3/04 (20130101) Original (OR) Class
B23H 7/28 (20130101)
B23H 2400/00 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 40/20 (20200101)
B33Y 80/00 (20141201)

Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor
C25F 3/16 (20130101)
C25F 7/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097645 Repko et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Dental and Craniofacial Research (NIDCR)
APPLICANT(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
ASSIGNEE(S) UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania)
INVENTOR(S) Alexander James Repko (Pittsburgh, Pennsylvania);  Kacey Gribbin Marra (Canonsburg, Pennsylvania);  Benjamin Schilling (Pittsburgh, Pennsylvania)
ABSTRACT The presently disclosed subject matter relates to systems for making an implantable construct comprising a reservoir coupled to the at least one frame; a mandrel base coupled to the at least one frame; a mandrel coupled to the mandrel base; a first mechanism configured to be coupled to the at least one frame and configured to move the at least one frame along a first axis; a second mechanism configured to be coupled to the at least one frame and configured to rotate the least one mandrel base along a second axis between a first orientation and a second orientation; and a container configured to be coupled to the at least one frame and configured to receive the mandrel in the second orientation. The disclosed mechanisms can manually, semi-automatically, or automatically control the movements of the at least one frame, reservoir, mandrel, mandrel base, and container to produce the construct with a lumen. The presently disclosed subject matter also relates to methods for making the construct.
FILED Tuesday, September 14, 2021
APPL NO 17/474197
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/18 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 41/14 (20130101) Original (OR) Class
B29C 41/22 (20130101)
B29C 41/52 (20130101)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2995/006 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/7532 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097939 Seeley
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
INVENTOR(S) Eric Seeley (Seebeck, Washington)
ABSTRACT A field configurable vehicle includes bladders located interior of the vehicle hull walls. One or more of the bladders can be filled with fluids of varying densities to manage the buoyancy, mass properties, and thermal heat dissipation of the vehicle.
FILED Friday, June 30, 2023
APPL NO 18/217517
ART UNIT 3617 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers
B63G 8/001 (20130101)
B63G 8/04 (20130101)
B63G 8/14 (20130101) Original (OR) Class
B63G 8/22 (20130101)
B63G 2008/004 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098062 Henderson
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
United States Marine Corps (USMC)
Marine Corps Systems Command (MARCORSYSCOM)
APPLICANT(S) Integrated Solutions for Systems, Inc. (Huntsville, Alabama)
ASSIGNEE(S) Integrated Solutions for Systems, Inc. (Huntsville, Alabama)
INVENTOR(S) Robert D. Henderson (Huntsville, Alabama)
ABSTRACT The present disclosure is an autonomous robotic cargo system for moving and accurately positioning cargo inside an aircraft or at any other designated location in an austere environment. The system has a chassis coupled to one or more tracks for moving the chassis from a first location to a second location. The chassis is also coupled to one or more forks for loading cargo and unloading the cargo. In addition, the chassis has a laser scanner positioned on the chassis to capture data indicative of the chassis' environment. The system further has a control processor that pre-generates a preliminary pathway for the chassis to travel from the first location to the second location based upon laser scanner data received from the laser scanner. The control processor also controls the one or more forks to pick up cargo and controls the one or more tracks to move the cargo from the first location to the second location.
FILED Wednesday, July 15, 2020
APPL NO 16/930073
ART UNIT 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Hoisting, Lifting, Hauling or Pushing, Not Otherwise Provided For, e.g Devices Which Apply a Lifting or Pushing Force Directly to the Surface of a Load
B66F 9/063 (20130101) Original (OR) Class
B66F 9/0755 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/024 (20130101)
G05D 1/027 (20130101)
G05D 1/0236 (20130101)
G05D 1/0242 (20130101)

Image Data Processing or Generation, in General
G06T 7/579 (20170101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098118 Fairbanks et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) Carolyn A. Fairbanks (Minneapolis, Minnesota);  Herbert T. Nagasawa (Minneapolis, Minnesota);  George L. Wilcox (Minneapolis, Minnesota);  Cristina D. Peterson (Minneapolis, Minnesota);  Kelley F. Kitto (Minneapolis, Minnesota)
ABSTRACT The invention provides a compound of formula I and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the formula I compounds, as well as methods of using such as therapeutic agents for the treatment of pain-related disorders and diseases and in combination with other therapeutic agents.
FILED Wednesday, November 06, 2019
APPL NO 17/291345
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 279/14 (20130101)
C07C 279/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098172 Dalton et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) The Johns Hopkins University (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) William Brian Dalton (Baltimore, Maryland);  Ben Ho Park (Perry Hall, Maryland);  Eric Christenson (Baltimore, Maryland)
ABSTRACT The present disclosure relates to compositions and methods for treating cancers. In particular, the present disclosure provides materials and methods for identifying mis-splicing-associated surface antigens (MASAs) generated by altered spliceosome proteins, as well as materials and methods for targeting cancerous tumors expressing MASAs.
FILED Tuesday, July 31, 2018
APPL NO 16/635861
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/435 (20130101) Original (OR) Class
C07K 14/70596 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2750/14143 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5011 (20130101)
G01N 33/5023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098193 Cukierman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Institute For Cancer Research (Philadelphia, Pennsylvania)
ASSIGNEE(S) Institute For Cancer Research (Philadelphia, Pennsylvania)
INVENTOR(S) Edna Cukierman (Philadelphia, Pennsylvania);  Ralph Francescone (Philadelphia, Pennsylvania);  Janusz Franco-Barraza (Philadelphia, Pennsylvania);  Kristopher Raghavan (Philadelphia, Pennsylvania)
ABSTRACT The present disclosure provides methods of inducing desmoplastic stroma to express a normal phenotype by detecting increased levels of NetG1 or NGL1 in tumor or in desmoplastic stroma isolated from a human subject, and/or detecting NetG1 in circulating extracellular vesicles, and/or detecting increased pFAK in the stroma, and treating the human subject with a therapeutic regimen; and by detecting NetG1 in a microvesicle isolated from a human subject, and/or treating the human subject with a therapeutic regimen.
FILED Tuesday, October 09, 2018
APPL NO 16/754877
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/217 (20130101)

Peptides
C07K 16/22 (20130101) Original (OR) Class
C07K 16/2818 (20130101)
C07K 16/2827 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57484 (20130101)
G01N 2800/7028 (20130101)
G01N 2800/7052 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098272 Reed et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) United States of America as Represented by The Secretary of The Army (Alexandria, Virginia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia)
INVENTOR(S) Julian H Reed (Champaign, Illinois);  Donald M Cropek (Champaign, Illinois)
ABSTRACT In one embodiment, a hydrogel-enzyme construct for performing high temperature enzymatic reaction on paraoxon, and/or for performing enzymatic reaction on paraoxon following exposure to high temperature, includes a hydrogel having multiple layers of poly(methacrylic acid) (PMAA) and a plurality of dPTE2 enzyme molecules. Individual dPTE2 enzyme molecules are embedded between adjacent PMAA layers and are covalently bonded with respective individual PMAA layers. The hydrogel-enzyme construct is capable of performing enzymatic reaction on the paraoxon when the paraoxon is exposed to the hydrogel-enzyme construct under a temperature condition of up to above 99° C. and below 100° C. or when the paraoxon is exposed to the hydrogel-enzyme construct after the hydrogel-enzyme construct has been heated to a temperature condition of up to 550° C., where the enzymatic reaction on the paraoxon by individual dPTE2 molecules embedded within the hydrogel occurs at a residual activity of between 20% and 100%.
FILED Monday, August 09, 2021
APPL NO 17/397967
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Compositions of Macromolecular Compounds
C08L 33/10 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/16 (20130101)

Enzymes
C12Y 301/08001 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098433 Jewett et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) NORTHWESTERN UNIVERSITY (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Michael Christopher Jewett (Evanston, Illinois);  Julius B. Lucks (Evanston, Illinois);  Adam D. Silverman (Chicago, Illinois);  Khalid K. Alam (Evanston, Illinois)
ABSTRACT Disclosed are methods, devices, kits, components, and compositions for detecting a target molecule in a test sample using a cell-free protein synthesis (CFPS) reaction. The methods, devices, kits, components, and compositions may be utilized for detecting target molecules which may include small molecules and/or metabolites of small molecules. The components and compositions used in the disclosed methods, devices, and kits may be dried or lyophilized and may be present or immobilized on a paper substrate, for example, as a paper test article.
FILED Monday, August 05, 2019
APPL NO 17/265785
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/485 (20130101)
C12Q 1/6897 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/184 (20240501)
G01N 33/521 (20130101)
G01N 33/1826 (20130101)
G01N 2430/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098475 Grotjohn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Air Force Office of Scientific Research (AFOSR)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan);  Fraunhofer USA (Plymouth, Michigan)
ASSIGNEE(S) BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan);  Fraunhofer USA (Plymouth, Michigan)
INVENTOR(S) Timothy A. Grotjohn (Okemos, Michigan);  Ramon Diaz (East Lansing, Michigan);  Aaron Hardy (East Lansing, Michigan)
ABSTRACT The disclosure relates to large area single crystal diamond (SCD) surfaces and substrates, and their methods of formation. Typical large area substrates can be at least about 25 mm, 50 mm, or 100 mm in diameter or square edge length, and suitable thicknesses can be about 100 μm to 1000 μm. The large area substrates have a high degree of crystallographic alignment. The large area substrates can be used in a variety of electronics and/or optics applications. Methods of forming the large area substrates generally include lateral and vertical growth of SCD on spaced apart and crystallographically aligned SCD seed substrates, with the individual SCD growth layers eventually merging to form a composite SCD layer of high quality and high crystallographic alignment. A diamond substrate holder can be used to crystallographically align the SCD seed substrates and reduce the effect of thermal stress on the formed SCD layers.
FILED Thursday, May 16, 2019
APPL NO 17/055943
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 25/04 (20130101)
C30B 25/08 (20130101)
C30B 25/12 (20130101)
C30B 25/16 (20130101)
C30B 25/20 (20130101)
C30B 25/025 (20130101) Original (OR) Class
C30B 29/04 (20130101)
C30B 29/68 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098916 Mellick et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) David A. Mellick (Hayden, Idaho);  Steven O. Troxel (Hayden, Idaho)
ABSTRACT An exemplary inventive freeboard detection system includes a tubular watertight temperature-sensing device and a computer. The temperature-sensing device includes a printed circuit board assembly (PCBA), a potting compound, and a hollow rigid tube. Inside the tube the potting compound encapsulates the PCBA, which includes a printed circuit board (PCB) and multiple temperature sensors closely and equidistantly arrayed along the length of the tube. The temperature-sensing device is vertically secured in a partially submerged state to a vessel with the expectation that some of the vertically arrayed temperature sensors will sense air temperature and others will sense water temperature. On an ongoing basis, the computer receives signals from the temperature sensors and processes the signals to monitor freeboard values, which the computer calculates based on differences in temperature measurements corresponding to pairs of consecutive (and/or nonconsecutive) temperature sensors. A maximum calculated difference in temperature measurements is indicative of the location of the water surface.
FILED Sunday, October 17, 2021
APPL NO 17/503324
ART UNIT 2863 — Printing/Measuring and Testing
CURRENT CPC
Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 21/085 (20130101) Original (OR) Class

Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 1/026 (20130101)
G01K 3/14 (20130101)

Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components
H05K 1/181 (20130101)
H05K 5/0039 (20130101)
H05K 5/064 (20130101)
H05K 2201/10151 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099045 Rubenstein et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) H. Mitchell Rubenstein (Beavercreek, Ohio);  Anthony Qualley (Washington Township, Ohio)
ABSTRACT A thermal desorption tube for chromatography and mass spectrometry analysis. The thermal desorption tube includes a sorbent and a plurality of focusing agents loaded at known, relative amounts onto the sorbent. Each focusing agent is a compound that chromatographically elutes within a retention time similar to a retention time of a target analyte and has a mass spectrum similar to a mass spectrum of the target analyte. The thermal desorption tube is configured to be further loaded with a sample having the target analyte.
FILED Wednesday, November 18, 2020
APPL NO 16/951626
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Separation
B01D 53/025 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/405 (20130101)
G01N 30/08 (20130101)
G01N 30/7206 (20130101)
G01N 30/8668 (20130101)
G01N 33/0006 (20130101)
G01N 33/0057 (20130101) Original (OR) Class
G01N 2030/025 (20130101)
G01N 2030/085 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099059 Biris et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
ASSIGNEE(S) BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas)
INVENTOR(S) Alexandru S. Biris (Little Rock, Arkansas);  Zeid Nima (Little Rock, Arkansas);  Yang Xu (Little Rock, Arkansas)
ABSTRACT A method of making at least one nanocomposite for surface enhanced Raman spectroscopy (SERS) detection of a target of interest includes forming at least one gold nanorod; coating a silver layer on an outer surface of the gold nanorod; assembling a Raman reporter molecule layer on the coated silver layer, wherein the Raman reporter molecule layer comprises Raman reporter molecules that are detectable by the SERS; coating a thiolated polyethylene glycol (PEG) layer on the assembled Raman reporter molecule layer; and conjugating the coated thiolated PEG layer with molecules of an antibody to make the at least one nanocomposite.
FILED Wednesday, September 30, 2020
APPL NO 17/037830
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/553 (20130101)
G01N 33/54346 (20130101) Original (OR) Class
G01N 33/54353 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099102 Solmeyer et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Honeywell International Inc. (Charlotte, North Carolina)
ASSIGNEE(S) Honeywell International Inc. (Charlotte, North Carolina)
INVENTOR(S) Neal Eldrich Solmeyer (Edina, Minnesota);  Matthew Wade Puckett (Phoenix, Arizona);  Matthew Robbins (Minneapolis, Minnesota);  Eugene Freeman (Eden Prairie, Minnesota);  Mary Salit (Plymouth, Minnesota)
ABSTRACT Systems and method for the delivery of a pump laser using optical diffraction are described herein. In certain embodiments, a system includes a substrate and a waveguide layer formed on the substrate. The waveguide layer includes a first waveguide of a first material configured to receive a probe laser for propagating within the first waveguide. The waveguide layer additionally includes a second waveguide configured to receive a pump laser for propagating within the second waveguide. Further, the waveguide layer includes one or more diffractors configured to direct a portion of the pump laser out of the second waveguide and through the first waveguide.
FILED Wednesday, April 20, 2022
APPL NO 17/725284
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/26 (20130101) Original (OR) Class

Optical Elements, Systems, or Apparatus
G02B 6/4215 (20130101)
G02B 6/29328 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099245 Toda et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) Intel Corporation (Santa Clara, California)
INVENTOR(S) Asako Toda (Santa Clara, California);  Chia-Pin Chiu (Tempe, Arizona);  Xiaoqian Li (Chandler, Arizona);  Yiqun Bai (Chandler, Arizona)
ABSTRACT Embodiments disclosed herein include optical packages. In an embodiment, an optical package comprises a package substrate, where the package substrate comprises a recessed edge. In an embodiment, a compute die is on the package substrate, and an optics die on the package substrate and overhanging the recessed edge of the package substrate. In an embodiment, an integrated heat spreader (IHS) is over the compute die and the optics die. In an embodiment, a lid covers the recess in the package substrate.
FILED Thursday, December 17, 2020
APPL NO 17/125481
ART UNIT 2874 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 6/4243 (20130101)
G02B 6/4253 (20130101) Original (OR) Class
G02B 6/4268 (20130101)
G02B 6/4269 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099538 Chew
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Peter A. Chew (Albuquerque, New Mexico)
ASSIGNEE(S) Galisteo Consulting Group, Inc. (Albuquerque, New Mexico)
INVENTOR(S) Peter A. Chew (Albuquerque, New Mexico)
ABSTRACT Disclosed is a flexible, scalable method for automatically distinguishing between the ‘mainstream’ and ‘fringe’ in any text dataset, such as unstructured social media data. The disclosed method allows analysts quickly to pinpoint text articulating fringe beliefs or theories, without prior knowledge of the nature of the fringe beliefs, and can be applied to text data in any language, provided the data can be represented electronically. The method works automatically and without any preconceived notions of what is important or what vocabulary is used in the context of certain beliefs. An analyst's attention is then quickly focused either on new conspiracy theories taking hold (potentially allowing decision-makers to act to interdict the ‘next QAnon insurrection’), or on well-founded beliefs that simply are not yet mainstream. Either way, analysts are empowered better to ‘connect the dots’ for a more complete understanding of the information environment.
FILED Friday, October 29, 2021
APPL NO 17/514283
ART UNIT 2656 — Digital Audio Data Processing
CURRENT CPC
Electric Digital Data Processing
G06F 16/35 (20190101) Original (OR) Class
G06F 18/231 (20230101)
G06F 40/284 (20200101)
G06F 2218/00 (20230101)

Image or Video Recognition or Understanding
G06V 30/416 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099903 Inoue et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) International Business Machines Corporation (Armonk, New York)
ASSIGNEE(S) INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York)
INVENTOR(S) Ken Inoue (Elmsford, New York);  Maika Takita (Croton on Hudson, New York);  Antonio Corcoles-Gonzalez (Mount Kisco, New York);  Scott Douglas Lekuch (New York, New York)
ABSTRACT One or more systems, devices, computer program products and/or computer-implemented methods of use provided herein relate to a process to dynamically determine a threshold for determining a state of a qubit and apply the threshold for operating a pulse to de-excite the qubit. A system can comprise a memory that stores computer executable components, and a processor that executes the computer executable components stored in the memory, wherein the computer executable components can comprise a decision component that is configured to determine a threshold of a plurality of thresholds to apply to measurement of a state of a qubit based on a probability distribution of state of the qubit, wherein a measurement at one side of the threshold is representative of the qubit being in the ground state, and wherein a measurement at another side of the threshold is representative of the qubit being in an excited state.
FILED Monday, July 18, 2022
APPL NO 17/813082
ART UNIT 2111 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/20 (20220101)
G06N 10/70 (20220101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12100539 Bennett et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Steven P. Bennett (Accokeek, Maryland);  Cory D. Cress (Springfield, Virginia);  Joseph Prestigiacomo (Huntington, Maryland);  Olaf M. J. van 't Erve (Falls Church, Virginia)
ABSTRACT Also disclosed herein is an article having a substrate and a layer of an FeRh alloy disposed on the substrate. The alloy has a continuous antiferromagnetic phase and one or more discrete phases smaller in area than the continuous phase having a lower metamagnetic transition temperature than the continuous phase. Also disclosed herein is a method of: providing an article having a substrate and a layer having a continuous phase of an antiferromagnetic FeRh alloy disposed on the substrate and directing an ion source at one or more portions of the alloy to create one or more discrete phases having a lower metamagnetic transition temperature than the continuous phase.
FILED Thursday, June 11, 2020
APPL NO 16/898851
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 10/002 (20130101) Original (OR) Class
H01F 10/14 (20130101)
H01F 10/28 (20130101)
H01F 41/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12100804 Angell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
ASSIGNEE(S) Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Charles Austen Angell (Mesa, Arizona);  Iolanda Santana Klein (Tempe, Arizona);  Telpriore Greg Tucker (Phoenix, Arizona)
ABSTRACT A solid electrolyte represented by general formula LiySiRx(MO4), where x is an integer from 1 to 3 inclusive, y=4−x, each R present is independently C1-C3 alkyl or C1-C3 alkoxy, and M is sulfur, selenium, or tellurium. Methods of making the solid electrolyte include combining a phenylsilane and a first acid to yield mixture including benzene and a second acid, and combining at least one of an alkali halide, and alkali amide, and an alkali alkoxide with the second acid to yield a product d represented by general formula LiySiRx(MO4)y. The second acid may be in the form of a liquid or a solid. The phenylsilane includes at least one C1-C3 alkyl substituent or at least one C1-C3 alkoxy substituent, and the first acid includes at least one of sulfuric acid, selenic acid, and telluric acid.
FILED Wednesday, June 07, 2023
APPL NO 18/330948
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/025 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/056 (20130101)
H01M 10/0525 (20130101)
H01M 10/0561 (20130101)
H01M 10/0562 (20130101)
H01M 10/0564 (20130101) Original (OR) Class
H01M 10/0565 (20130101)
H01M 10/0567 (20130101)
H01M 2300/006 (20130101)
H01M 2300/0065 (20130101)
H01M 2300/0068 (20130101)
H01M 2300/0091 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12100848 Evans et al.
FUNDED BY
Department of Defense (DOD)
Missile Defense Agency (MDA)
APPLICANT(S) Aspen Aerogels, Inc. (Northborough, Massachusetts)
ASSIGNEE(S) Aspen Aerogels, Inc. (Northborough, Massachusetts)
INVENTOR(S) Owen Evans (Chelmsford, Massachusetts);  Nicholas Zafiropoulos (Wayland, Massachusetts);  Shannon White (Hudson, Massachusetts);  Wenting Dong (Marlborough, Massachusetts);  Wendell Rhine (Belmont, Massachusetts)
ABSTRACT The present invention provides a fiber-reinforced aerogel material which can be used as insulation. The fiber-reinforced aerogel material is highly durable, flexible, and has a thermal performance that exceeds the insulation materials currently used. The fiber-reinforced aerogel insulation material can be as thin as 1 mm or less, and can have a thickness variation as low as 2% or less. Also provided is a method for improving the performance of a battery by incorporating a reinforced aerogel material into the battery. Further provided is a casting method for producing thin fiber-reinforced aerogel materials.
FILED Monday, December 04, 2023
APPL NO 18/528371
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 13/0091 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 6/36 (20130101)
H01M 6/5072 (20130101)
H01M 50/116 (20210101)
H01M 50/117 (20210101)
H01M 50/121 (20210101)
H01M 50/122 (20210101)
H01M 50/124 (20210101)
H01M 50/131 (20210101)
H01M 50/133 (20210101)
H01M 50/138 (20210101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12101357 Soroush et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Palo Alto Research Center Incorporated (Palo Alto, California)
ASSIGNEE(S) Xerox Corporation (Norwalk, Connecticut)
INVENTOR(S) Hamed Soroush (San Jose, California);  Milad Asgari Mehrabadi (Irvine, California);  Shantanu Rane (Menlo Park, California);  Massimiliano Albanese (Potomac, Maryland)
ABSTRACT Embodiments provide a system and method for constructing a graph-based model for optimizing the security posture of a composed system. During operation, the system constructs a multi-layer graph for a system with a plurality of components, wherein the multi-layer graph comprises a configuration subgraph, a vulnerability subgraph, and a dependency subgraph. The system constructs the multi-layer graph by the following. The system generates nodes in the configuration subgraph, including: nodes in a first class which encode information associated with a configuration parameter for a respective component, wherein the encoded information includes a name, a default value, a range of values, and a data type; and nodes in a second class which encode value assignments for configuration parameters and relationships between configuration parameters. The system generates nodes in the vulnerability subgraph based on known vulnerabilities associated with a component, bad security practices, and best security practices.
FILED Wednesday, July 01, 2020
APPL NO 16/918971
ART UNIT 2496 — Cryptography and Security
CURRENT CPC
Electric Digital Data Processing
G06F 16/252 (20190101)
G06F 21/577 (20130101)
G06F 2221/034 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/04 (20130101)
G06N 5/04 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/205 (20130101) Original (OR) Class
H04L 63/1433 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12101693 Borel-Donohue
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) U.S. Gov't as Represented by Sec of Army c/o U.S Army DEVCOM Army Research Laboratory (Adelphi, Maryland);  U.S. Gov, as represented by the Sec of Army c/o U.S. Army DEVCOM Army Research Laboratory (Adelphi, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Christoph C. Borel-Donohue (Silver Spring, Maryland)
ABSTRACT Methods, systems, and computer code on computer-readable media are provided that are directed to generating area skyline data using a digital elevation or surface models (DEMs or DESs) and shadow casting techniques. Some embodiments use an area of maximum shadow line overlap, for shadow line images based on target location skyline azimuth and elevation angle data, as the best approximation for the position of the target location in an area. Some embodiments select the location showing the best fit to the target skyline azimuth and elevation angle data as the best approximation for the target location.
FILED Thursday, May 25, 2023
APPL NO 18/202086
ART UNIT 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/3602 (20130101)

Image Data Processing or Generation, in General
G06T 7/75 (20170101)
G06T 15/60 (20130101)
G06T 2207/30244 (20130101)
G06T 2215/12 (20130101)

Image or Video Recognition or Understanding
G06V 20/39 (20220101)

Wireless Communication Networks
H04W 4/029 (20180201) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12101870 Kobernik et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Department of Energy (DOE)
APPLICANT(S) SHINE Technologies, LLC (Janesville, Wisconsin)
ASSIGNEE(S) SHINE Technologies, LLC (Janesville, Wisconsin)
INVENTOR(S) Arne Kobernik (Monona, Wisconsin);  Carl Sherven (Monona, Wisconsin);  Casey Lamers (Monona, Wisconsin);  Chris Seyfert (Monona, Wisconsin);  Evan Sengbusch (Monona, Wisconsin);  Gabriel Becerra (Monona, Wisconsin);  Jin Lee (Monona, Wisconsin);  Logan Campbell (Monona, Wisconsin);  Mark Thomas (Monona, Wisconsin);  Michael Taylor (Monona, Wisconsin);  Preston Barrows (Monona, Wisconsin);  Ross Radel (Monona, Wisconsin);  Tye Gribb (Monona, Wisconsin)
ABSTRACT Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes.
FILED Monday, January 09, 2023
APPL NO 18/094724
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 37/08 (20130101)
H01J 37/32082 (20130101)
H01J 41/04 (20130101)
H01J 41/14 (20130101)

Spark Gaps; Overvoltage Arresters Using Spark Gaps; Sparking Plugs; Corona Devices; Generating Ions to be Introduced into Non-enclosed Gases
H01T 23/00 (20130101)

Electric Heating; Electric Lighting Not Otherwise Provided for
H05B 31/26 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/46 (20130101)
H05H 1/54 (20130101)
H05H 1/4622 (20210501)
H05H 3/06 (20130101)
H05H 5/04 (20130101)
H05H 6/00 (20130101)
H05H 7/22 (20130101) Original (OR) Class
H05H 9/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12102005 Schwede et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Spark Thermionics, Inc. (Berkeley, California)
ASSIGNEE(S) Spark Thermionics, Inc. (Berkeley, California)
INVENTOR(S) Jared William Schwede (Berkeley, California);  Lucas Heinrich Hess (Berkeley, California)
ABSTRACT A thermionic energy converter, preferably including an anode and a cathode. An anode of a thermionic energy converter, preferably including an n-type semiconductor, one or more supplemental layers, and an electrical contact. A method for work function reduction and/or thermionic energy conversion, preferably including inputting thermal energy to a thermionic energy converter, illuminating an anode of the thermionic energy converter, thereby preferably reducing a work function of the anode, and extracting electrical power from the system.
FILED Wednesday, November 23, 2022
APPL NO 17/993195
ART UNIT 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 45/00 (20130101)

Electric solid-state devices not otherwise provided for
H10N 10/13 (20230201) Original (OR) Class
H10N 10/851 (20230201)
H10N 10/853 (20230201)
H10N 10/855 (20230201)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 12096999 Frederick et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Telemedicine and Advanced Technology Research Center (TATRC)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Tom Frederick (Lincoln, Nebraska);  Eric Markvicka (Brush, Colorado);  Shane Farritor (Lincoln, Nebraska);  Dmitry Oleynikov (Omaha, Nebraska)
ABSTRACT The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices.
FILED Thursday, August 04, 2022
APPL NO 17/880823
ART UNIT 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/14 (20130101)
A61B 18/082 (20130101)
A61B 18/1445 (20130101)
A61B 34/30 (20160201) Original (OR) Class
A61B 2017/00398 (20130101)
A61B 2017/00407 (20130101)
A61B 2017/00477 (20130101)
A61B 2018/00595 (20130101)
A61B 2018/1253 (20130101)
A61B 2018/1422 (20130101)
A61B 2034/305 (20160201)
A61B 2217/005 (20130101)
A61B 2217/007 (20130101)
A61B 2218/002 (20130101)
A61B 2218/007 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/046 (20130101)
B25J 9/0087 (20130101)
B25J 9/102 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097015 Boamah et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S) Northwestern University (Evanston, Illinois);  CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) Northwestern University (Evanston, Illinois);  California Institute of Technology (Pasadena, California)
INVENTOR(S) Mavis D. Boamah (Evanston, Illinois);  Franz M. Geiger (Evanston, Illinois);  Thomas F. Miller, III (South Pasadena, California);  Jeongmin Kim (Pasadena, California)
ABSTRACT Energy harvesting devices and methods for converting the mechanical energy of a flowing ionic solution, such as rainwater or seawater, into electric energy are provided. The energy harvesting devices include an electric current generating device that includes a metal layer and an amphoteric metal oxide film disposed over a surface of the metal layer. By moving an electric double layer across the surface of the amphoteric metal oxide film, an electric current is generated in the metal layer.
FILED Tuesday, September 17, 2019
APPL NO 17/276684
ART UNIT 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/026 (20130101) Original (OR) Class

Electric Machines Not Otherwise Provided for
H02N 1/08 (20130101)
H02N 11/002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097159 Walsh et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Conor J. Walsh (Cambridge, Massachusetts);  Ciaran O'Neill (Cambridge, Massachusetts);  Nathan Phipps (Somerville, Massachusetts)
ABSTRACT A textile actuator worn by a user comprises a textile envelope that defines a chamber made fluid-impermeable by a fluid-impermeable bladder contained in the textile envelope and/or a fluid-impermeable structure incorporated into the textile envelope. The textile envelope has a pre-determined geometry that produces an equilibrium state at a non-180-angle displacement and that stops further displacement upon pressurization of the chamber and prevents over-extension the joint. A fluid is delivered into or out of the chamber to displace the textile envelope primarily by transitioning from an uninflated state to the pre-determined geometry due to displacement of the textile envelope rather than via stretching or contraction of the textile envelope. When actuated, the textile actuator (a) displaces a body segment of the user and/or (b) supports and holds the body segment of the user in place.
FILED Thursday, May 31, 2018
APPL NO 16/614862
ART UNIT 3785 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Outerwear; Protective Garments; Accessories
A41D 1/04 (20130101)

Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body
A61H 1/0274 (20130101) Original (OR) Class
A61H 2201/0103 (20130101)
A61H 2201/165 (20130101)
A61H 2201/1238 (20130101)
A61H 2201/1635 (20130101)
A61H 2201/1659 (20130101)
A61H 2201/5058 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/0006 (20130101)
B25J 9/1694 (20130101)

Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for
F15B 15/103 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097239 Rivera-Feliciano et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jose Rivera-Feliciano (Brookline, Massachusetts);  Edwin Rosado-Olivieri (Somerville, Massachusetts);  Douglas A. Melton (Lexington, Massachusetts)
ABSTRACT A previously uncharacterized gene and gene product are disclosed herein that increase blood glucose clearance independent of insulin. Also described is a methodology for enriching for mRNAs transcribing excreted and membrane bound proteins as well as a non-human animal expressing a labeled SEC61b protein.
FILED Monday, September 23, 2019
APPL NO 17/278644
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/1709 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097290 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Liangfang Zhang (San Diego, California);  Che-Ming (Jack) Hu (San Diego, California);  Ronnie Hongbo Fang (Irvine, California);  Jonathan Copp (La Jolla, California)
ABSTRACT Provided are nanoparticles and methods of using and making thereof. The inventive nanoparticle comprises a) an inner core comprising a non-cellular material; and b) an outer surface comprising a cellular membrane derived from a cell or a membrane derived from a virus. Medicament delivery systems or pharmaceutical compositions comprising the inventive nanoparticles are also provided. Further provided are immunogenic compositions comprising the inventive nanoparticles, and methods of using the inventive immunogenic compositions for eliciting an immune response, and for treating or preventing diseases or condition, such as neoplasm or cancer, or disease or conditions associated with cell membrane inserting toxin. Vaccines comprising the immunogenic composition comprising the nanoparticles are also provided.
FILED Thursday, March 14, 2013
APPL NO 13/827906
ART UNIT 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/148 (20130101) Original (OR) Class
A61K 39/39 (20130101)
A61K 39/085 (20130101)
A61K 39/001102 (20180801)
A61K 45/06 (20130101)
A61K 2039/80 (20180801)
A61K 2039/55555 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097475 Ismagilov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Rustem F. Ismagilov (Chicago, Illinois);  Bo Zheng (Chicago, Illinois);  Cory John Gerdts (Chicago, Illinois)
ABSTRACT The present invention provides microfluidic technology enabling rapid and economical manipulation of reactions on the femtoliter to microliter scale.
FILED Friday, January 12, 2024
APPL NO 18/412395
ART UNIT 1796 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 25/314 (20220101)
B01F 33/3021 (20220101) Original (OR) Class

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 19/0046 (20130101)
B01J 2219/0059 (20130101)
B01J 2219/00522 (20130101)
B01J 2219/00585 (20130101)
B01J 2219/00599 (20130101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/06 (20130101)
B01L 3/0293 (20130101)
B01L 3/527 (20130101)
B01L 3/502723 (20130101)
B01L 3/502746 (20130101)
B01L 3/502784 (20130101)
B01L 2200/0673 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0838 (20130101)
B01L 2300/0864 (20130101)
B01L 2300/0867 (20130101)
B01L 2400/0406 (20130101)
B01L 2400/0409 (20130101)
B01L 2400/0415 (20130101)
B01L 2400/0433 (20130101)
B01L 2400/0487 (20130101)

Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor
C30B 7/00 (20130101)
C30B 29/58 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/38 (20130101)
G01N 35/08 (20130101)
G01N 2035/1034 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 7/0694 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 137/0318 (20150401)
Y10T 436/12 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097620 Tan et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee)
ASSIGNEE(S) University of Tennesse Research Foundation (Knoxville, Tennessee)
INVENTOR(S) Jindong Tan (Knoxville, Tennessee);  Da Hu (Louisville, Tennessee);  Qiang He (Knoxville, Tennessee);  Shuai Li (Knoxville, Tennessee)
ABSTRACT Provided are methods and apparatus for environment-adaptive robotic disinfecting. In an example, provided is a method that can include (i) creating, from digital images, a map of a structure; (ii) identifying a location of a robot in the structure; (iii) segmenting, using a machine learning-based classifying algorithm trained based on object affordance information, the digital images to identify potentially contaminated surfaces within the structure; (iv) creating a map of potentially contaminated surfaces within the structure; (v) calculating a trajectory of movement of the robot to move the robot to a location of a potentially contaminated surface in the potentially contaminated surfaces; and (vi) moving the robot along the trajectory of movement to position a directional decontaminant source adjacent to the potentially contaminated surface. Other methods, systems, and computer-readable media are also disclosed.
FILED Wednesday, August 25, 2021
APPL NO 17/445898
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 2/24 (20130101)
A61L 2202/14 (20130101)
A61L 2202/16 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 5/007 (20130101)
B25J 9/161 (20130101)
B25J 9/1664 (20130101) Original (OR) Class
B25J 9/1669 (20130101)
B25J 15/0019 (20130101)

Electric Digital Data Processing
G06F 18/2148 (20230101)

Image or Video Recognition or Understanding
G06V 10/25 (20220101)
G06V 20/20 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097878 Gaffin-Cahn
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Industrial Innovation and Partnerships (IIP)
APPLICANT(S) Perceptive Automata, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Perceptive Automata, Inc. (Boston, Massachusetts)
INVENTOR(S) Elon Gaffin-Cahn (Boston, Massachusetts)
ABSTRACT A system receives information describing paths traversed by vehicles of a vehicle type, for example, a bicycle or a motorcycle. The system determines locations along the paths. For each location the system determines a measure of likelihood of encountering vehicles of the vehicle type in traffic at the location. The system selects a subset of locations based on the measure of likelihood and obtains sensor data captured at the subset of locations. The system uses the sensor data as training dataset for training a machine learning based model configured to receive input sensor data describing traffic and output a score used for navigation of autonomous vehicles. The machine learning model is provided to a vehicle, for example, an autonomous vehicle for navigation of the autonomous vehicle.
FILED Tuesday, April 26, 2022
APPL NO 17/730048
ART UNIT 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 40/04 (20130101)
B60W 60/0011 (20200201) Original (OR) Class
B60W 2554/402 (20200201)
B60W 2554/4041 (20200201)
B60W 2556/10 (20200201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098026 Li et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
ASSIGNEE(S) RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey)
INVENTOR(S) Guohong Li (Highland Park, New Jersey);  Eva Y. Andrei (Highland Park, New Jersey);  Angela Coe (Tenstrike, Minnesota)
ABSTRACT A system for transferring objects into a device inside a controlled environment includes a winch, tool and carousel. The winch includes a drum, and wire arrangement configured to be reversibly wound onto the drum by a first drive. The tool is suspended below a distal end of the wire arrangement and configured to suspend an object. Both the tool and the object are sized to fit inside a device located below the winch. The carousel is connected to a second drive configured to rotate the carousel around a vertical axis, and includes a storage space centered at a first horizontal angle and a pass-through opening at a different second horizontal angle. The pass-through opening being large enough to pass the tool and the object as the wire arrangement is unwound from the drum thereby lowering the tool and object inside the device.
FILED Wednesday, April 17, 2019
APPL NO 15/733768
ART UNIT 3654 — Material and Article Handling
CURRENT CPC
Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors
B65G 1/045 (20130101)
B65G 1/0464 (20130101) Original (OR) Class

Cranes; Load-engaging Elements or Devices for Cranes, Capstans, Winches, or Tackles
B66C 1/24 (20130101)

Capstans; Winches; Tackles, e.g Pulley Blocks; Hoists
B66D 1/26 (20130101)

Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports
F16M 13/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098456 Rajagopalan et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Jagannathan Rajagopalan (Tempe, Arizona);  Paul Rasmussen (Tempe, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Jagannathan Rajagopalan (Tempe, Arizona);  Paul Rasmussen (Tempe, Arizona)
ABSTRACT Methods for controlled microstructure creation utilize seeding of amorphous layers prior to annealing. Seed crystals are formed on an amorphous layer or layers. The material, size, and spacing of the seed crystals may be varied, and multiple seed layers and/or amorphous layers may be utilized. Thereafter, the resulting assembly is annealed to generate a crystalline microstructure. Via use of these methods, devices having desirable microstructural properties are enabled.
FILED Wednesday, August 18, 2021
APPL NO 17/405194
ART UNIT 1712 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 14/024 (20130101) Original (OR) Class
C23C 14/5806 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12098471 Wang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) The Trustees of Boston College (Chestnut Hill, Massachusetts)
ASSIGNEE(S) The Trustees of Boston College (Chestnut Hill, Massachusetts)
INVENTOR(S) Dunwei Wang (Newton, Massachusetts);  Qi Dong (Newton, Massachusetts);  Xizi Zhang (Berkeley, California)
ABSTRACT A flow cell for reducing carbon dioxide may include a first chamber having a gold coated gas diffusion layer working electrode, a reference electrode, and a water-in-salt electrolyte comprising a super concentrated aqueous solution of lithium bis-(trifluoromethanesulfonyl)imide (LiTFSI). A second chamber adjacent the first chamber has a gold coated gas diffusion layer counter electrode and the water-in-salt electrolyte. The second chamber being separated from the first chamber by a proton exchange membrane. A reservoir coupled to each of the first and the second chambers with a pump contains a volume of the water-in-salt electrolyte and a head space.
FILED Tuesday, February 28, 2023
APPL NO 18/175782
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor
C25B 1/04 (20130101)
C25B 1/23 (20210101)
C25B 9/15 (20210101) Original (OR) Class
C25B 9/19 (20210101)
C25B 11/032 (20210101)
C25B 11/077 (20210101)
C25B 11/081 (20210101)
C25B 15/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099012 Ly et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of Mental Health (NIMH)
National Science Foundation (NSF)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Victoria Ly (Santa Cruz, California);  Pierre Baudin (Santa Cruz, California);  Pattawong Pansodtee (Santa Cruz, California);  Erik Jung (Santa Cruz, California);  Robert Currie (Santa Cruz, California);  David Haussler (Santa Cruz, California);  Mircea Teodorescu (Santa Cruz, California)
ABSTRACT An imaging system includes an imaging device having a holder configured to hold a cell culture plate with a plurality of wells. The imaging device also includes an imaging assembly having a plurality of imaging units, each of which is configured to image one well of the plurality of wells. The imaging system also includes a storage platform in communication with the imaging device configured to receive a plurality of images from the imaging device. The system further includes a computer in communication with the imaging device and the storage platform. The computer is configured to control the imaging device and to display at least one image of the plurality of images.
FILED Friday, May 06, 2022
APPL NO 17/738251
ART UNIT 2485 — Recording and Compression
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 25/06 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101) Original (OR) Class
G01N 21/6486 (20130101)
G01N 2201/021 (20130101)
G01N 2201/062 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/365 (20130101)

Image Data Processing or Generation, in General
G06T 7/571 (20170101)
G06T 2207/10056 (20130101)
G06T 2207/10148 (20130101)
G06T 2207/30024 (20130101)
G06T 2207/30072 (20130101)

Pictorial Communication, e.g Television
H04N 5/265 (20130101)
H04N 23/62 (20230101)
H04N 23/66 (20230101)
H04N 23/90 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 12096728 Dreschel et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as Represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Thomas W. Dreschel (Titusville, Florida);  Jacob J. Torres (Cocoa, Florida)
ABSTRACT The invention described herein comprises a passive plant nutrient delivery system that utilizes a hydrophilic porous tube to transfer a liquid nutrient solution from at least one reservoir to the roots of plants. The plants' roots rest on the exterior surface of the tube, where a combination of capillary force, evapotranspiration from the plant, and some evaporation from the surface of the tube draws the nutrient solution passively from the reservoir, or reservoirs, through the tube. The roots uptake water from the tube as needed, requiring no external power source. A flexible cover envelops plants' roots and the tube, whereby the cover has an opening to allow room for plants to grow. The flexible cover is held in place by a securing means, such as a clamp. Both the cover and the securing means are comprised of a material that can expand, allowing the plants adequate room to grow.
FILED Wednesday, September 16, 2020
APPL NO 17/023336
ART UNIT 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering
A01G 27/06 (20130101)
A01G 27/008 (20130101)
A01G 31/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12096999 Frederick et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Telemedicine and Advanced Technology Research Center (TATRC)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
National Science Foundation (NSF)
Directorate for STEM Education (EDU)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
ASSIGNEE(S) Board of Regents of the University of Nebraska (Lincoln, Nebraska)
INVENTOR(S) Tom Frederick (Lincoln, Nebraska);  Eric Markvicka (Brush, Colorado);  Shane Farritor (Lincoln, Nebraska);  Dmitry Oleynikov (Omaha, Nebraska)
ABSTRACT The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices.
FILED Thursday, August 04, 2022
APPL NO 17/880823
ART UNIT 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/14 (20130101)
A61B 18/082 (20130101)
A61B 18/1445 (20130101)
A61B 34/30 (20160201) Original (OR) Class
A61B 2017/00398 (20130101)
A61B 2017/00407 (20130101)
A61B 2017/00477 (20130101)
A61B 2018/00595 (20130101)
A61B 2018/1253 (20130101)
A61B 2018/1422 (20130101)
A61B 2034/305 (20160201)
A61B 2217/005 (20130101)
A61B 2217/007 (20130101)
A61B 2218/002 (20130101)
A61B 2218/007 (20130101)

Manipulators; Chambers Provided With Manipulation Devices
B25J 9/046 (20130101)
B25J 9/0087 (20130101)
B25J 9/102 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099006 Bulcha
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Berhanu Bulcha (Greenbelt, Maryland)
ABSTRACT A heterodyne-based submillimeter-wave spectrometer includes a frequency mixer that combine a local oscillator (LO) signal and a radio frequency (RF) signal to translate from a high frequency to a lower frequency or an intermediate frequency (IF) signal.
FILED Wednesday, August 24, 2022
APPL NO 17/894534
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/3581 (20130101) Original (OR) Class

Demodulation or Transference of Modulation From One Carrier to Another
H03D 7/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099219 Murphey et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Thomas W. Murphey (Fort Collins, Colorado);  Patrick A. Rodriguez (Fort Collins, Colorado)
ASSIGNEE(S) Opterus Research and Development, Inc. (Fort Collins, Colorado)
INVENTOR(S) Thomas W. Murphey (Fort Collins, Colorado);  Patrick A. Rodriguez (Fort Collins, Colorado)
ABSTRACT A doubly curved reflector for compact storage in a folded state includes a plurality of gores, each gore having on either long side a gore side curve. At least one hinge is mechanically coupled between each adjacent gore, the at least one hinge including a fold roll hinge or a living hinge. In a stowed doubly curved reflector state each gore folds about the at least one hinge when folded closed such that a face surface of each gore folds against an adjacent face surface of another gore into a substantially cylindrical structure. In a deployed doubly curved reflector state, each hinge. A doubly curved reflector for compact storage in a folded state and a locked open state, a method of manufacture, and a method for designing a substantially wrinkle free doubly curved foldable reflector having gores of a composite material are also described.
FILED Friday, August 04, 2023
APPL NO 18/230411
ART UNIT 2872 — Optics
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/443 (20130101)

Optical Elements, Systems, or Apparatus
G02B 5/10 (20130101) Original (OR) Class
G02B 27/0012 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12099880 Liaghati
FUNDED BY
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
APPLICANT(S) The Boeing Company (Chicago, Illinois)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Amir Leon Liaghati (Huntsville, Alabama)
ABSTRACT A system selects a telemetry allocation for the transmission of data from multiple transmitters. An allocation matrix defines a split ratio for data generated by a data source that is split between transmitters. The split ratio is defined for each data source of a plurality of data sources. (A) A storage buffer model is executed based on the allocation matrix to simulate a buffer that stores data from each data source that exceeds a download bandwidth value. (B) Performance parameter values are stored in association with the allocation matrix. (C) The allocation matrix is updated to redefine at least one split ratio. (D) (A) through (C) is repeated with the allocation matrix replaced with the updated allocation matrix until each unique permutation of values for the split ratio is processed. An allocation matrix is selected from allocation matrices stored in (B) based on the plurality of performance parameter values.
FILED Tuesday, October 05, 2021
APPL NO 17/493996
ART UNIT 2194 — Interprocess Communication and Software Development
CURRENT CPC
Electric Digital Data Processing
G06F 9/5022 (20130101)
G06F 9/5044 (20130101) Original (OR) Class
G06F 11/323 (20130101)
G06F 11/3089 (20130101)
G06F 11/3466 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 12101394 Vemury
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Arun Vemury (North Bethesda, Maryland)
ABSTRACT Systems and methods for secure distribution of biometric matching processing are provided. Certain configurations include homomorphic encrypting of captured biometric information. In some configurations, the biometric information is classified without decryption between a first identity class and a second identity class. The biometric information may be formed as a feature vector. A homomorphic encrypted feature vector may be formed by homomorphic encrypting of the biometric information.
FILED Friday, December 01, 2023
APPL NO 18/526977
ART UNIT 2436 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/008 (20130101) Original (OR) Class
H04L 9/3231 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US D1043717 Boyd et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Daniel A. Boyd (Arlington, Virginia);  Kelli L. Biegger (Alexandria, Virginia)
ABSTRACT
FILED Thursday, October 27, 2022
APPL NO 29/858020
ART UNIT 2923 — Design
CURRENT CPC
Recording, communication, or information retrieval equipment
D14/485
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 12096863 Cooper et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) University of Pittsburg Of the Commonweath System of Higher Education (Pittsburgh, Pennsylvania);  The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Rory Alan Cooper (Gibsonia, Pennsylvania);  Michael A. Shulock (Murrysville, Pennsylvania);  Joshua D. Brown (Pittsburgh, Pennsylvania);  Garrett G. Grindle (Pittsburgh, Pennsylvania);  Benjamin Todd Gebrosky (Gibsonia, Pennsylvania);  Sayeedur Rahman (Issaquah, Washington);  Sivan Almosnino (Snoqualmie, Washington);  Lisa Garamella (Charlotte, North Carolina);  Daniel Robin (Seattle, Washington)
ABSTRACT An access system includes a laterally extending frame, a carriage in operative connection with the laterally extending frame and including a drive to move the carriage laterally on the frame, a seat support attached to the carriage including a seat assembly interface and a lift to raise and lower the seat assembly interface within a range of positions, a seat assembly attached to the seat assembly interface, a controller in operative connection with the drive of the carriage and the lift of the seat support via which the position of the seat support is controllable, and a controller interface in operative connection with the controller.
FILED Tuesday, August 31, 2021
APPL NO 17/462462
ART UNIT 3632 — Static Structures, Supports and Furniture
CURRENT CPC
Chairs; Sofas; Beds
A47C 1/025 (20130101)
A47C 1/0242 (20130101)
A47C 3/20 (20130101)
A47C 7/62 (20130101) Original (OR) Class
A47C 7/5064 (20180801)

Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices
A61G 5/04 (20130101)
A61G 5/128 (20161101)
A61G 5/1059 (20130101)
A61G 5/1067 (20130101)
A61G 2200/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097367 Sabiev et al.
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Anton Sabiev (Forest Hills, New York);  William Bauman (New Rochelle, New York);  Mark Korsten (Hastings-on-Hudson, New York)
ABSTRACT An iontophoresis system for positioning against skin of a subject is disclosed. The iontophoresis system can comprise at least one vessel having a solvent therein. An anode apparatus can couple to the at least one vessel. The anode apparatus can comprise a first reservoir configured to receive the solvent from the at least one vessel so that, when received into the first reservoir, the solvent makes contact with the skin of the subject, and a first electrode positioned above the first reservoir. A cathode apparatus can couple to the at least one vessel. The cathode apparatus can comprise a second reservoir configured to receive the solvent from the at least one vessel so that, when received into the first reservoir, the solvent makes contact with the skin of the subject, and a second electrode positioned above the second reservoir.
FILED Wednesday, May 04, 2022
APPL NO 17/736602
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 1/30 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 12097268 Horsager et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) EOS Neuroscience, Inc. (San Francisco, California)
ASSIGNEE(S) EOS Neuroscience, Inc. (San Francisco, California)
INVENTOR(S) Alan Horsager (Los Angeles, California);  Andrew Smith (Santa Monica, California);  Benjamin C. Matteo (San Francisco, California)
ABSTRACT Provided herein are compositions and methods for the design of synthetic regulatory sequences and for subsequent modulation of neural pathways.
FILED Thursday, March 19, 2020
APPL NO 16/823905
ART UNIT 1638 — Central Reexamination Unit (Chemical)
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 48/0058 (20130101) Original (OR) Class

Peptides
C07K 14/4702 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 2750/14043 (20130101)
C12N 2830/007 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12097567 Herrington et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Voxel Innovations, Inc. (Raleigh, North Carolina)
ASSIGNEE(S) Voxel Innovations, Inc. (Raleigh, North Carolina)
INVENTOR(S) Daniel Herrington (Raleigh, North Carolina);  Eric Rountree (Raleigh, North Carolina)
ABSTRACT A technique of removing material from metal parts referred to as OPECM and a corresponding OPECM processing machine are disclosed. A tool electrode is manufactured for removing material from a target workpiece, and the workpiece and tool electrode are fixed into a processing machine that imparts an oscillatory motion path or profile and applies a voltage through a flowing electrolyte solution. The disclosed technique and processing machine removes material from the surface of the target workpiece through proximal surface dissolution as the workpiece and tool electrode are brought within proximity of one another.
FILED Thursday, December 30, 2021
APPL NO 17/565817
ART UNIT 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 10/62 (20210101)

Working of Metal by the Action of a High Concentration of Electric Current on a Workpiece Using an Electrode Which Takes the Place of a Tool; Such Working Combined With Other Forms of Working of Metal
B23H 3/04 (20130101) Original (OR) Class
B23H 7/28 (20130101)
B23H 2400/00 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 40/20 (20200101)
B33Y 80/00 (20141201)

Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor
C25F 3/16 (20130101)
C25F 7/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US PP36135 McMahon et al.
FUNDED BY
Department of Energy (DOE)
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
ASSIGNEE(S) REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota)
INVENTOR(S) Bernard G. McMahon (Coon Rapids, Minnesota);  William Berguson (Duluth, Minnesota)
ABSTRACT The invention is a new and distinct variety of male Populus tree named ‘NextGen’ that is characterized by its superior to above average field growth performance, its excellent to above average rooting rate, its disease resistance to foliar rusts (Melampsora sp.), leaf spots (Marssonina sp.) and stem cankers (Septoria sp.), its vigorous vegetative growth and production in nursery stoolbeds, its cold hardiness for overwintering and surviving in Minnesota with no frost damage, its wide-spread superior growth performance in many test locations (ie: MN, MI, WI, IA, IN, NY, etc); able to be considered “geo-robust” after years of testing, its replicated growth testing and evidence of promising performance and evaluation in phytoremediation research testing and applications, and its male flowers that do not produce seeds.
FILED Wednesday, November 22, 2023
APPL NO 18/517841
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/218
VIEW PATENT @ USPTO:  Full Text   PDF 

Environmental Protection Agency (EPA) 

US 12097546 Scheckel et al.
FUNDED BY
Environmental Protection Agency (EPA)
APPLICANT(S) United States Government, as represented by the Administrator of the U.S. EPA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES GOVERNMENT, AS REPRESENTED BY THE ADMINISTRATOR OF THE U.S. EPA (Washington, District of Columbia)
INVENTOR(S) Kirk Gerald Scheckel (Cincinnati, Ohio);  Ranju R. Karna (Clinton, Mississippi);  Charles R. Partridge (Commerce City, Colorado);  Karen D. Bradham (Apex, North Carolina);  David James Thomas (Chapel Hill, North Carolina);  Matthew R. Noerpel (Cincinnati, Ohio);  Jennifer Lynn Goetz (Petersburg, Kentucky);  Todd Peter Luxton (Cincinnati, Ohio);  Tyler Dale Sowers (Apex, North Carolina)
ABSTRACT Methods and systems are provided for treating a contaminated environmental medium. In one example, the treatment includes adding a first jarosite-group mineral to the contaminated environmental medium to form a wet mixture under a set of conditions. The set of conditions is maintained over a duration of time to expedite precipitation of a second jarosite-group mineral, the second jarosite-group mineral incorporating contaminant cations and contaminant anions into a structure of the second jarosite-group mineral. The first jarosite-group mineral is added in situ at a contamination site.
FILED Thursday, July 21, 2022
APPL NO 17/814172
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Reclamation of Contaminated Soil
B09C 1/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 12099961 Lawson et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Angela Dawn Lawson (Cambridge, Massachusetts);  Fatema Momenni Kennedy (Dumfries, Virginia);  Junghyun Hwang (Herndon, Virginia)
ABSTRACT A system and method for tracking and managing package delivery within a distribution network. Many events happen during the processing, moving, and delivery of a package. Systems and methods herein identify whether all expected events occur, whether scan locations are correct, whether delivery times are met, and other requirements. Problems or potential problems can be identified and corrected.
FILED Monday, January 11, 2021
APPL NO 17/145719
ART UNIT 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing
CURRENT CPC
Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/0633 (20130101)
G06Q 10/0833 (20130101) Original (OR) Class
G06Q 10/06393 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 12101346 Blumenfeld et al.
FUNDED BY
APPLICANT(S) Two Six Labs, LLC (Arlington, Virginia)
ASSIGNEE(S) Two Six Labs, LLC (Arlington, Virginia)
INVENTOR(S) Ian T. Blumenfeld (Arlington, Virginia);  David Renardy (Arlington, Virginia)
ABSTRACT A method for assessing a regular expression for vulnerability to ReDoS attacks includes receiving a regular expression for evaluating a string defined by ordered set of characters from an alphanumeric input device, and evaluating the regular expression for determining if a parsing operation of the string according to the regular expression results in a disproportionate resource consumption. The evaluation determines if the resource consumption constitutes a Regular expression Denial of Service (ReDOS) attack by providing a vulnerability indication of a single valid attack string, rather than attempting to find all possible attack strings. The valid attack string is defined by an input string for which evaluation based on the regular expression would result in disproportionate resource consumption.
FILED Wednesday, July 26, 2023
APPL NO 18/226509
ART UNIT 2435 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 63/1425 (20130101)
H04L 63/1433 (20130101) Original (OR) Class
H04L 63/1458 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, September 24, 2024.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240924.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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