FedInvent™ Patents
Patent Details for Tuesday, September 24, 2024
This page was updated on Thursday, September 26, 2024 at 04:05 AM GMT
Department of Health and Human Services (HHS)
US 12096986 | Chatzizisis |
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FUNDED BY |
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APPLICANT(S) | The Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
ASSIGNEE(S) | The Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
INVENTOR(S) | Ioannis S. Chatzizisis (Omaha, Nebraska) |
ABSTRACT | In accordance with embodiments of this disclosure, a computational simulation platform comprises a computer-implemented method that includes: generating a mesh or meshless three-dimensional (3D) reconstruction of a vessel lumen and a surface of the vessel lumen based on invasive or non-invasive imaging; assigning material properties to the 3D reconstructed surface of the vessel lumen based on the invasive or non-invasive imaging; performing balloon pre-dilation, stenting and balloon post-dilation computational simulations with the 3D reconstructed vessel lumen and surface of the vessel lumen; and assessing stent and vessel morphometric and biomechanical measures based on the computational simulations. |
FILED | Friday, May 07, 2021 |
APPL NO | 17/314338 |
ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/10 (20160201) Original (OR) Class A61B 90/37 (20160201) A61B 2034/102 (20160201) A61B 2034/105 (20160201) A61B 2090/378 (20160201) A61B 2090/3762 (20160201) Image Data Processing or Generation, in General G06T 17/20 (20130101) G06T 2210/41 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097015 | Boamah et al. |
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APPLICANT(S) | Northwestern University (Evanston, Illinois); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois); California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Mavis D. Boamah (Evanston, Illinois); Franz M. Geiger (Evanston, Illinois); Thomas F. Miller, III (South Pasadena, California); Jeongmin Kim (Pasadena, California) |
ABSTRACT | Energy harvesting devices and methods for converting the mechanical energy of a flowing ionic solution, such as rainwater or seawater, into electric energy are provided. The energy harvesting devices include an electric current generating device that includes a metal layer and an amphoteric metal oxide film disposed over a surface of the metal layer. By moving an electric double layer across the surface of the amphoteric metal oxide film, an electric current is generated in the metal layer. |
FILED | Tuesday, September 17, 2019 |
APPL NO | 17/276684 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/026 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) H02N 11/002 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097037 | Javitt et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York); The Nathan S. Kline Institute for Psychiatric Research (Orangeburg, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York); The Nathan S. Kline Institute for Psychiatric Research (Orangeburg, New York) |
INVENTOR(S) | Daniel Javitt (Fort Lee, New Jersey); Antigona Martinez (New York, New York); Yaakov Stern (New York, New York) |
ABSTRACT | An exemplary system, method, and computer-accessible medium for generating diagnostic data associated with a likelihood a patient(s) developing a mental disease(s) can be provided, which can include, for example, providing a visual patterns to the patient(s), receiving electroencephalogram (EEG) information from the patient(s) that can be based on the visual pattern(s); and generating the diagnostic data based on the EEG information. |
FILED | Wednesday, June 20, 2018 |
APPL NO | 16/624452 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/374 (20210101) A61B 5/378 (20210101) Original (OR) Class A61B 5/4088 (20130101) A61B 5/7257 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097055 | Stayman et al. |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | Joseph Webster Stayman (Baltimore, Maryland); Jianan Gang (Baltimore, Maryland) |
ABSTRACT | In some implementations, a device may obtain scan information associated with scanning a section of a body that includes an object within tissue of the section. The device may determine a region of the section that is likely to be represented by an artifact in an image obtained using a first scanning type of a medical image device. The device may determine a plurality of scan patterns for scanning the region using a second scanning type. The device may determine, for the plurality of scan patterns, individual scan scores associated with scanning the region. The device may select, based on the individual scan scores, an optimal scan pattern from the plurality of scan patterns. The device may transmit the optimal scan pattern to the medical imaging device to permit the medical imaging device to scan the section to obtain optimized image data associated with the region. |
FILED | Friday, September 25, 2020 |
APPL NO | 17/753726 |
ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/032 (20130101) Original (OR) Class A61B 6/54 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097075 | Alizad et al. |
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FUNDED BY |
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APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
INVENTOR(S) | Azra Alizad (Rochester, Minnesota); Mostafa Fatemi (Rochester, Minnesota); Juanjuan Gu (Rochester, Minnesota) |
ABSTRACT | Ultrasound systems and methods are provided using mass characterization frequency methods that provide for predicting benign or malignant lesions, a response to treatment, tumor grading, and/or the expressions of immunohistochemical biomarkers, which are currently used for breast cancer classification and hormone therapy determination. The systems and methods are based on the shear wave parameter, mass characteristic frequency. The status of malignancy, treatment response, grade, and/or each immunohistochemical biomarker may be determined based on a corresponding mass characteristic frequency threshold. |
FILED | Friday, September 03, 2021 |
APPL NO | 17/466073 |
ART UNIT | 3797 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/085 (20130101) A61B 8/485 (20130101) A61B 8/0825 (20130101) A61B 8/4488 (20130101) A61B 8/5215 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097135 | Raaz et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
ASSIGNEE(S) | Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
INVENTOR(S) | Uwe Raaz (Leipzig, Germany); Isabel Schellinger (Leipzig, Germany); Joshua Spin (San Jose, California); Philip Tsao (Los Altos, California) |
ABSTRACT | Methods, compositions, and devices for treating a vascular aneurysm, including an abdominal aortic aneurysm, are disclosed. In particular, the various embodiments relate to a method of treating an abdominal aortic aneurysm by increasing the mechanical stiffness of an aortic segment adjacent to the abdominal aortic aneurysm in a subject. The mechanical stiffness of the adjacent aortic segment may be increased, for example, by applying a surgical adhesive or intravascular stent. Such treatment reduces stress on the aortic wall and limits further growth of the abdominal aortic aneurysm. |
FILED | Tuesday, September 22, 2020 |
APPL NO | 17/028048 |
ART UNIT | 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/00491 (20130101) A61B 2017/00778 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/82 (20130101) Original (OR) Class A61F 2/90 (20130101) A61F 2002/823 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097196 | Newman et al. |
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APPLICANT(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
INVENTOR(S) | Amy Hauck Newman (Phoenix, Maryland); Vivek Kumar (Baltimore, Maryland); Anver Basha Shaik (Baltimore, Maryland) |
ABSTRACT | Disclosed herein are novel methods of treating pain in a patient in need thereof by providing to the patient a selective dopamine D3 receptor antagonist/partial agonist which when used with an opioid analgesic, can mitigate the development of opioid dependence, by preventing the need for dose escalation while either maintaining the opioid analgesic effect or providing analgesia with a lower dose of the opioid. In addition, the D3 antagonists/partial agonists described herein may be used to augment the effectiveness of current Medication Assisted Treatment regimens (e.g. methadone or buprenorphine) for the treatment of opioid use disorders. |
FILED | Friday, May 06, 2022 |
APPL NO | 17/738301 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) A61K 31/496 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/36 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097213 | Shay et al. |
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APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
ASSIGNEE(S) | The Board of Regents of The University of Texas System (Austin, Texas) |
INVENTOR(S) | Jerry Shay (Dallas, Texas); Yang-Xin Fu (Dallas, Texas); Ilgen Mender (Dallas, Texas); Anli Zhang (Dallas, Texas) |
ABSTRACT | Disclosed herein are methods of treatments with a telomerase-mediated telomere-targeting drug, 6-thio-2′-deoxyguanosine (6-thio-dG), checkpoint inhibitors and/or radiation therapy for treating cancers. Leads to tumor regression in innate and adaptive immune-dependent manners in syngeneic and humanized mouse cancer models. |
FILED | Friday, March 12, 2021 |
APPL NO | 17/200539 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7076 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) C07K 16/2827 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097237 | Briesewitz et al. |
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FUNDED BY |
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APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
INVENTOR(S) | Roger Briesewitz (Columbus, Ohio); Dehua Pei (Columbus, Ohio); Punit Upadhyaya (Columbus, Ohio) |
ABSTRACT | Disclosed herein are novel compounds that are Ras inhibitors. Also disclosed are compositions comprising the compounds and methods of using the compounds in treating various diseases. |
FILED | Wednesday, July 01, 2020 |
APPL NO | 16/919031 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/01 (20130101) A61K 38/00 (20130101) A61K 38/012 (20130101) Original (OR) Class A61K 38/12 (20130101) A61K 39/3955 (20130101) A61K 47/6811 (20170801) A61K 47/6849 (20170801) A61K 2039/585 (20130101) A61K 2039/627 (20130101) A61K 2300/00 (20130101) Peptides C07K 7/64 (20130101) C07K 14/4703 (20130101) C07K 16/2863 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097246 | Labhasetwar et al. |
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APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
INVENTOR(S) | Vinod Labhasetwar (Cleveland, Ohio); Hayder H. Jaffer (Cleveland, Ohio) |
ABSTRACT | The invention is directed to a method of treating a spinal cord injury, a neurodegenerative disease or a neuronal injury in an individual in need thereof comprising administering an effective amount of superoxide dismutase (SOD) and catalase to the individual, wherein the superoxide dismutase and the catalase are encapsulated in one or more nanoparticles that release the SOD and catalase upon administration. Another aspect of the invention is directed to compositions comprising superoxide dismutase (SOD) and catalase encapsulated in one or more nanoparticles. |
FILED | Wednesday, June 22, 2022 |
APPL NO | 17/846130 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 9/5153 (20130101) A61K 38/44 (20130101) A61K 38/446 (20130101) Original (OR) Class Enzymes C12Y 111/01006 (20130101) C12Y 115/01001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097258 | Klein et al. |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Bruce Steven Klein (Madison, Wisconsin); Huafeng Wang (San Diego, California); Marcel Wuethrich (Madison, Wisconsin); Tristan Theodore Brandhorst (Madison, Wisconsin) |
ABSTRACT | A Dectin-2 ligand vaccine adjuvant and a method of making and using the Dectin-2 ligand vaccine adjuvant in a vaccine to immunize a patient are disclosed. Also discloses is a vaccine composition comprising a Bl-Eng2 antigen and methods of using the vaccine composition to immunize a subject against a fungal infection. |
FILED | Friday, February 26, 2021 |
APPL NO | 17/186366 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0002 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/57 (20130101) A61K 2039/55516 (20130101) A61K 2039/55566 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097260 | Overstreet |
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APPLICANT(S) | Sonoran Biosciences, Inc. (Tempe, Arizona) |
ASSIGNEE(S) | Sonoran Biosciences, Inc. (Tempe, Arizona) |
INVENTOR(S) | Derek J. Overstreet (Tempe, Arizona) |
ABSTRACT | A polymer composition can include an aqueous vehicle and a temperature-responsive degradable polymer having a polymer including a LCST-imparting unit and a lactone-bearing unit including a pendent lactone group. The number of LCST-imparting units is greater than the number of lactone-bearing units. The temperature-responsive degradable polymer has an initial lower critical solution temperature (LCST) of 37° C. or below. The polymer composition can have a pH lower than 7. |
FILED | Tuesday, November 16, 2021 |
APPL NO | 17/528111 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/2096 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 31/435 (20130101) A61K 31/702 (20130101) A61K 31/7036 (20130101) A61K 47/32 (20130101) Original (OR) Class Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/19 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/58 (20130101) C08F 2800/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097264 | Khaled et al. |
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APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida); Sanford Burnham Prebys Medical Discovery Institute at Lake Nona (Orlando, Florida); Memorial Sloan Kettering Cancer Center (New York, New York) |
ASSIGNEE(S) | University of Central Florida Research Foundation, Inc., et al. (Orlando, Florida); Sanford Burnham Prebys Medical Discovery Institute at Lake Nona (Orlando, Florida); , Memorial Sloan Kettering Cancer Center (New York, New York) |
INVENTOR(S) | Annette Khaled (Orlando, Florida); Jesus Manuel Perez Figueroa (Los Angeles, California); Santimukul Santra (Pittsburg, Kansas); Charalambos Kaittanis (Cambridge, Massachusetts); Oscar Santiesteban (El Segundo, California); Jan Grimm (Larchmont, New York); Hampton Sessions (Orlando, Florida) |
ABSTRACT | Provided herein is a nanoparticle for drug delivery, wherein the nanoparticle comprises a hyperbranched polyester (HBPE) nanoparticle having a hydrophobic interior, polyglutamate folate ligands conjugated to the nanoparticle, and one or more PET detectable isotopes. Also provided herein are methods of using thereof. |
FILED | Monday, April 12, 2021 |
APPL NO | 17/228286 |
ART UNIT | 3991 — Central Reexamination Unit (Chemical) |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 45/06 (20130101) A61K 47/6869 (20170801) Original (OR) Class A61K 47/6935 (20170801) A61K 51/1072 (20130101) A61K 51/1244 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097268 | Horsager et al. |
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APPLICANT(S) | EOS Neuroscience, Inc. (San Francisco, California) |
ASSIGNEE(S) | EOS Neuroscience, Inc. (San Francisco, California) |
INVENTOR(S) | Alan Horsager (Los Angeles, California); Andrew Smith (Santa Monica, California); Benjamin C. Matteo (San Francisco, California) |
ABSTRACT | Provided herein are compositions and methods for the design of synthetic regulatory sequences and for subsequent modulation of neural pathways. |
FILED | Thursday, March 19, 2020 |
APPL NO | 16/823905 |
ART UNIT | 1638 — Central Reexamination Unit (Chemical) |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) Original (OR) Class Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14043 (20130101) C12N 2830/007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097290 | Zhang et al. |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Liangfang Zhang (San Diego, California); Che-Ming (Jack) Hu (San Diego, California); Ronnie Hongbo Fang (Irvine, California); Jonathan Copp (La Jolla, California) |
ABSTRACT | Provided are nanoparticles and methods of using and making thereof. The inventive nanoparticle comprises a) an inner core comprising a non-cellular material; and b) an outer surface comprising a cellular membrane derived from a cell or a membrane derived from a virus. Medicament delivery systems or pharmaceutical compositions comprising the inventive nanoparticles are also provided. Further provided are immunogenic compositions comprising the inventive nanoparticles, and methods of using the inventive immunogenic compositions for eliciting an immune response, and for treating or preventing diseases or condition, such as neoplasm or cancer, or disease or conditions associated with cell membrane inserting toxin. Vaccines comprising the immunogenic composition comprising the nanoparticles are also provided. |
FILED | Thursday, March 14, 2013 |
APPL NO | 13/827906 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/148 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 39/085 (20130101) A61K 39/001102 (20180801) A61K 45/06 (20130101) A61K 2039/80 (20180801) A61K 2039/55555 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097291 | Hassett et al. |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado); SOLIGENIX, INC. (Princeton, New Jersey) |
ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado); Soligenix, Inc. (Princeton, New Jersey) |
INVENTOR(S) | Kimberly Hassett (Medford, Massachusetts); Pradyot Nandi (Denver, Colorado); Robert N. Brey (Lakeside, Illinois); John Carpenter (Littleton, Colorado); Theodore Randolph (Niwot, Colorado) |
ABSTRACT | Compositions relating to thermostable vaccines and methods of preparing the same. Specifically, methods of preparing thermostable vaccines based on a recombinant ricin neurotoxin protein and uses of co-adjuvants to develop a composition capable of eliciting an immune response in a subject. |
FILED | Monday, May 10, 2021 |
APPL NO | 17/316585 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) Original (OR) Class A61K 39/00 (20130101) A61K 39/39 (20130101) A61K 47/26 (20130101) A61K 2039/55505 (20130101) A61K 2039/55572 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097475 | Ismagilov et al. |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Rustem F. Ismagilov (Chicago, Illinois); Bo Zheng (Chicago, Illinois); Cory John Gerdts (Chicago, Illinois) |
ABSTRACT | The present invention provides microfluidic technology enabling rapid and economical manipulation of reactions on the femtoliter to microliter scale. |
FILED | Friday, January 12, 2024 |
APPL NO | 18/412395 |
ART UNIT | 1796 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 25/314 (20220101) B01F 33/3021 (20220101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/0059 (20130101) B01J 2219/00522 (20130101) B01J 2219/00585 (20130101) B01J 2219/00599 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/06 (20130101) B01L 3/0293 (20130101) B01L 3/527 (20130101) B01L 3/502723 (20130101) B01L 3/502746 (20130101) B01L 3/502784 (20130101) B01L 2200/0673 (20130101) B01L 2300/0816 (20130101) B01L 2300/0838 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2400/0406 (20130101) B01L 2400/0409 (20130101) B01L 2400/0415 (20130101) B01L 2400/0433 (20130101) B01L 2400/0487 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/00 (20130101) C30B 29/58 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) G01N 35/08 (20130101) G01N 2035/1034 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 7/0694 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) Y10T 436/12 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097645 | Repko et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Alexander James Repko (Pittsburgh, Pennsylvania); Kacey Gribbin Marra (Canonsburg, Pennsylvania); Benjamin Schilling (Pittsburgh, Pennsylvania) |
ABSTRACT | The presently disclosed subject matter relates to systems for making an implantable construct comprising a reservoir coupled to the at least one frame; a mandrel base coupled to the at least one frame; a mandrel coupled to the mandrel base; a first mechanism configured to be coupled to the at least one frame and configured to move the at least one frame along a first axis; a second mechanism configured to be coupled to the at least one frame and configured to rotate the least one mandrel base along a second axis between a first orientation and a second orientation; and a container configured to be coupled to the at least one frame and configured to receive the mandrel in the second orientation. The disclosed mechanisms can manually, semi-automatically, or automatically control the movements of the at least one frame, reservoir, mandrel, mandrel base, and container to produce the construct with a lumen. The presently disclosed subject matter also relates to methods for making the construct. |
FILED | Tuesday, September 14, 2021 |
APPL NO | 17/474197 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/14 (20130101) Original (OR) Class B29C 41/22 (20130101) B29C 41/52 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/006 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7532 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098117 | Thiele et al. |
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FUNDED BY |
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APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Dennis J. Thiele (Chapel Hill, North Carolina); Bushu Dong (Durham, North Carolina); Alexander M. Jaeger (Cambridge, Massachusetts); Philip F. Hughes (Chapel Hill, North Carolina); Timothy Haystead (Durham, North Carolina); Jiyong Hong (Durham, North Carolina) |
ABSTRACT | This disclosure relates to compounds, pharmaceutical compositions comprising them, and methods of using the compounds and compositions for treating diseases related to Heat Shock Transcription Factor 1 (HSF1) activity and/or function. More particularly, this disclosure relates to methods of inhibiting HSF1 activity with these compounds and pharmaceutical compositions thereof, and methods of treating diseases associated with HSF1 activity and/or function, such as cancer. |
FILED | Wednesday, December 11, 2019 |
APPL NO | 17/312858 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 211/40 (20130101) C07C 255/60 (20130101) C07C 275/28 (20130101) C07C 275/30 (20130101) Original (OR) Class C07C 275/34 (20130101) C07C 275/40 (20130101) C07C 275/42 (20130101) C07C 279/18 (20130101) C07C 279/28 (20130101) C07C 281/06 (20130101) C07C 311/46 (20130101) C07C 317/36 (20130101) C07C 317/42 (20130101) Heterocyclic Compounds C07D 213/40 (20130101) C07D 213/75 (20130101) C07D 223/04 (20130101) C07D 229/02 (20130101) C07D 231/56 (20130101) C07D 233/64 (20130101) C07D 241/24 (20130101) C07D 249/14 (20130101) C07D 271/12 (20130101) C07D 285/10 (20130101) C07D 317/66 (20130101) C07D 333/20 (20130101) C07D 333/36 (20130101) C07D 333/72 (20130101) C07D 405/04 (20130101) C07D 405/12 (20130101) C07D 417/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098131 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
INVENTOR(S) | Jinkun Chen (Lexington, Massachusetts); Qisheng Tu (Newton, Massachusetts); Xingwen Wu (Boston, Massachusetts); Gang Chen (Shanghai, China PRC); Wei Qiu (Boston, Massachusetts) |
ABSTRACT | Disclosed herein are adiponectin receptor agonists and methods of using the same for the treatment of inflammation or bone loss in a subject. |
FILED | Wednesday, April 12, 2023 |
APPL NO | 18/299266 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/08 (20180101) A61P 29/00 (20180101) Heterocyclic Compounds C07D 211/58 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098153 | Chen et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
INVENTOR(S) | Yu Chen (Tampa, Florida); Michael Sacco (Tampa, Florida); James Leahy (Tampa, Florida); Elena Bray (Tampa, Florida); Xingmin Sun (Tampa, Florida); Xiujun Zhang (Tampa, Florida) |
ABSTRACT | Disclosed herein are compounds that can prevent and treat C. difficile by inhibiting sporulation. Also disclosed herein are compositions and formulations comprising the compound disclosed herein. Methods of preventing and treating C. difficile comprising administering the compounds described herein are also disclosed. |
FILED | Wednesday, October 04, 2023 |
APPL NO | 18/376525 |
ART UNIT | 1621 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 471/08 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098169 | Dong et al. |
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FUNDED BY |
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APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts); Paul Stenmark (Stockholm, Sweden) |
ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
INVENTOR(S) | Min Dong (Weatogue, Connecticut); Paul Stenmark (Stockholm, Sweden); Sicai Zhang (Boston, Massachusetts); Andrew Doxey (Waterloo, Canada) |
ABSTRACT | Provided herein is a novel homolog of Clostridial botulinum neurotoxin (BoNT) identified in the bacterial species Enterococcus faecium (BoNT/EN). BoNT/EN variants and chimeric toxins comprising domains from BoNT/EN and other BoNTs are also provided. Further provided herein are methods of producing BoNT/EN and its use, e.g., in therapeutic applications. |
FILED | Friday, September 28, 2018 |
APPL NO | 16/651720 |
ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/33 (20130101) C07K 14/315 (20130101) Original (OR) Class C07K 2319/50 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098170 | Sahay et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida); RISE THERAPEUTICS, LLC (Rockville, Maryland) |
ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida); RISE THERAPEUTICS, LLC (Rockville, Maryland) |
INVENTOR(S) | Bikash Sahay (Gainesville, Florida); Gary Fanger (Rockville, Maryland); Jyoti Jha (Clarksburg, Maryland); Christian Furlan Freguia (Germantown, Maryland) |
ABSTRACT | The current invention provides a recombinant bacterium, the recombinant bacterium being genetically modified to synthesize surface layer protein A (SlpA). Efficacious therapies for a subject suffering from an inflammation mediated disease are also provided. The methods of the current invention comprise administering to a subject in need thereof a therapeutically effective amount of the recombinant bacterium, for example L. lactis cells, or a therapeutically effective amount of the isolated SlpA. The recombinant bacteria cells or SlpA isolated from the recombinant bacteria can be in a pharmaceutical composition comprising a pharmaceutically acceptable carrier and/or excipient. |
FILED | Friday, June 10, 2022 |
APPL NO | 18/568888 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/164 (20130101) A61K 45/06 (20130101) Peptides C07K 14/335 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098184 | Sivaramakrishnan et al. |
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FUNDED BY |
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APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Sivaraj Sivaramakrishnan (North Oaks, Minnesota); Keehun Kim (Minneapolis, Minnesota) |
ABSTRACT | The systems and methods described herein include the use of Giant Plasma Membrane Vesicles (GPMVs) derived from cells expressing SPASM sensors (e.g., SPASM GPCR sensors). Herein provided are giant plasma membrane vesicle (GPMV) sensors containing a membrane-associated polypeptide, where the membrane-associated polypeptide contains a target G protein-coupled receptor (GPCR), a linker including an amino acid sequence flanked by a FRET donor and a FRET acceptor, and a receptor partner for the target GPCR, where the linker separates the target GPCR from the receptor partner. In another aspect, provided is a method for quantifying the intrinsic efficacy of a compound for a target GPCR. In another aspect, provided is a method for identifying a compound that interacts with a target GPCR. |
FILED | Tuesday, December 04, 2018 |
APPL NO | 16/769852 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 14/723 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/542 (20130101) G01N 33/566 (20130101) G01N 2333/726 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098187 | Ho et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | David D. Ho (Chappaqua, New York); Yaoxing Huang (Brooklyn, New York); Jian Yu (New Providence, New Jersey) |
ABSTRACT | In various embodiments, the present invention relates generally to using bispecific antibodies in the prevention and treatment of HIV. |
FILED | Thursday, December 20, 2018 |
APPL NO | 16/770840 |
ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 16/2812 (20130101) C07K 16/2866 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/52 (20130101) C07K 2317/66 (20130101) C07K 2317/76 (20130101) C07K 2317/94 (20130101) C07K 2317/567 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098188 | Bakaletz et al. |
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FUNDED BY |
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APPLICANT(S) | Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
ASSIGNEE(S) | Research Institute at Nationwide Children's Hospital (Columbus, Ohio) |
INVENTOR(S) | Lauren O. Bakaletz (Hilliard, Ohio); Steven D. Goodman (Hilliard, Ohio) |
ABSTRACT | This disclosure provides antibody fragments and isolated polypeptides comprising the antibody fragments that are useful as a therapeutic for those with an existing infection characterized by the formation of biofilms. Antibody fragments and isolated polypeptides comprising the antibody fragments can be administered to detect, treat, or prevent infection and/or remediate biofilms. Bacteria that cannot form functional biofilms are more readily cleared by the remainder of the host's immune system and/or traditional antibiotics. |
FILED | Wednesday, January 03, 2018 |
APPL NO | 16/475654 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/10 (20200101) A01N 63/50 (20200101) A01N 63/50 (20200101) Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/52 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 16/1203 (20130101) Original (OR) Class C07K 16/1242 (20130101) C07K 2317/24 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) G01N 2333/285 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098190 | Song et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); KIRA PHARMACEUTICALS (US) LLC (Arlington, Massachusetts) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania and (Pennsylvania, Pennsylvania); Kira Pharmaceuticals (US) LLC (Arlington, Massachusetts) |
INVENTOR(S) | Wenchao Song (Bryn Mawr, Pennsylvania); Takashi Miwa (Bala Cynwyd, Pennsylvania); Damodar Gullipalli (Philadelphia, Pennsylvania); Ping Tsui (North Potomac, Maryland); Sayaka Sato (Philadelphia, Pennsylvania) |
ABSTRACT | This invention relates to inhibition of the complement signaling using an anti-C5 antibody. Specifically, the invention relates to methods of treating a complement-mediated disease or complement-mediated disorder in an individual by contacting the individual with an anti-C5 antibody. |
FILED | Friday, September 06, 2019 |
APPL NO | 17/273753 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/02 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/94 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098193 | Cukierman et al. |
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FUNDED BY |
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APPLICANT(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
INVENTOR(S) | Edna Cukierman (Philadelphia, Pennsylvania); Ralph Francescone (Philadelphia, Pennsylvania); Janusz Franco-Barraza (Philadelphia, Pennsylvania); Kristopher Raghavan (Philadelphia, Pennsylvania) |
ABSTRACT | The present disclosure provides methods of inducing desmoplastic stroma to express a normal phenotype by detecting increased levels of NetG1 or NGL1 in tumor or in desmoplastic stroma isolated from a human subject, and/or detecting NetG1 in circulating extracellular vesicles, and/or detecting increased pFAK in the stroma, and treating the human subject with a therapeutic regimen; and by detecting NetG1 in a microvesicle isolated from a human subject, and/or treating the human subject with a therapeutic regimen. |
FILED | Tuesday, October 09, 2018 |
APPL NO | 16/754877 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/217 (20130101) Peptides C07K 16/22 (20130101) Original (OR) Class C07K 16/2818 (20130101) C07K 16/2827 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 2800/7028 (20130101) G01N 2800/7052 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098286 | Choi et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Northeastern University (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Northeastern University (Boston, Massachusetts) |
INVENTOR(S) | Hak Soo Choi (Needham, Massachusetts); Jonghan Kim (Cambridge, Massachusetts); Georges El Fakhri (Brookline, Massachusetts) |
ABSTRACT | Provided herein are compounds that are able to bind metal ions (e.g., free metal ions or metal ions bound to low affinity ligands) in a sample or subject. Also provided herein are methods of using the compounds for chelating metal ions and for the treatment of diseases associated with abnormal levels of metal ions. Methods of preparing the compounds and pharmaceutical compositions are also provided. |
FILED | Monday, May 15, 2023 |
APPL NO | 18/197560 |
ART UNIT | 1626 — Organic Chemistry |
CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 23/0025 (20130101) C09B 23/0033 (20130101) C09B 23/0041 (20130101) C09B 23/0066 (20130101) Original (OR) Class C09B 69/105 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098353 | McCain et al. |
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FUNDED BY |
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APPLICANT(S) | University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | University of Southern California (Los Angeles, California); Children's Hospital of Los Angeles (Los Angeles, California) |
INVENTOR(S) | Megan McCain (Los Angeles, California); Joycelyn Yip (Los Angeles, California); Ching-Ling Lien (Los Angeles, California); Michael Harrison (Los Angeles, California) |
ABSTRACT | Zebrafish are a powerful model for investigating cardiac repair due to their unique regenerative abilities, scalability, and compatibility with many genetic tools. However, characterizing the regeneration process in live adult zebrafish hearts has proved challenging because adult fish are opaque and explanted hearts in conventional culture conditions experience rapid declines in morphology and physiology. To overcome these limitations, we fabricated a fluidic device for culturing explanted adult zebrafish hearts with constant media perfusion that is also compatible with live imaging. Unlike hearts cultured in dishes for one week, the morphology and calcium activity of hearts cultured in the device for one week were largely similar to freshly explanted hearts. We also cultured injured hearts in the device and used live imaging techniques to continuously record the revascularization process over several days, demonstrating how our device enables unprecedented visual access to the multi-day process of adult zebrafish heart regeneration. |
FILED | Wednesday, March 22, 2023 |
APPL NO | 18/124923 |
ART UNIT | 1796 — Organic Chemistry |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0247 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2200/0684 (20130101) B01L 2300/12 (20130101) B01L 2300/087 (20130101) B01L 2300/0877 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) Original (OR) Class C12M 23/22 (20130101) C12M 23/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098363 | Bauer et al. |
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FUNDED BY |
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APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts); UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
INVENTOR(S) | Daniel E. Bauer (Cambridge, Massachusetts); Scot Wolfe (Boston, Massachusetts); Mehmet Fatih Bolukbasi (Brighton, Massachusetts); Benjamin Roscoe (Worcester, Massachusetts); Pengpeng Liu (Worcester, Massachusetts); Kevin Luk (Worcester, Massachusetts); Yuxuan Wu (Boston, Massachusetts); Jing Zeng (Boston, Massachusetts) |
ABSTRACT | Provided herein are methods and compositions for increasing fetal hemoglobin levels in a cell by disrupting BCL11A expression at the genomic level. Also provided herein are methods and compositions relating to the treatment of hemoglobinopathies by reinduction of fetal hemoglobin levels. |
FILED | Friday, July 20, 2018 |
APPL NO | 16/964461 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/01 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/20 (20170501) C12N 2510/00 (20130101) C12N 2800/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098366 | Weiss et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Ron Weiss (Newton, Massachusetts); Jin Huh (Watertown, Massachusetts) |
ABSTRACT | Disclosed herein is a subgenomic promoter library derived from alphavirus. Also provided herein are methods of using the subgenomic promoters to produce antibodies and other molecules. |
FILED | Friday, February 07, 2020 |
APPL NO | 16/784962 |
ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/1072 (20130101) C12N 15/1086 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098380 | Yao |
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FUNDED BY |
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APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
INVENTOR(S) | Feng Yao (Southborough, Massachusetts) |
ABSTRACT | Provided herein are Vero cell lines that stably express Herpes Simplex Virus (HSV) ICP0 protein. These cells have the same morphology of Vero cells, exhibit stable expression of HSV ICP0 protein, and also efficiently complement replication of HSV ICP0 deficient virus for greater than 20, 30, or even 40 cell passages. |
FILED | Tuesday, June 05, 2018 |
APPL NO | 16/619416 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/245 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/16 (20130101) C12N 5/0686 (20130101) C12N 7/025 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2710/16622 (20130101) C12N 2710/16643 (20130101) C12N 2710/16652 (20130101) C12N 2830/003 (20130101) C12N 2830/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098381 | Pederson et al. |
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FUNDED BY |
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APPLICANT(S) | University of Massachusetts (Boston, Massachusetts); University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
INVENTOR(S) | Thoru Pederson (Worcester, Massachusetts); Scot Andrew Wolfe (Winchester, Massachusetts); Hanhui Ma (Shrewsbury, Massachusetts); Metewo Selase Kosi Enuameh (Gaithersburg, Maryland); Nicola Anne Kearns (Somerville, Massachusetts); Ryan Michael Jude Genga (Framingham, Massachusetts); Rene Maehr (Newton, Massachusetts); Shaojie Zhang (Oviedo, Florida); Ardalan Naseri (Orlando, Florida); Manuel Garber (Winchester, Massachusetts) |
ABSTRACT | The present disclosure relates to methods of and systems for modifying the transcriptional regulation of stem or progenitor cells to promote their differentiation or reprogramming of somatic cells. Further, the labeling and editing of human genomic loci in live cells with three orthogonal CRISPR/Cas9 components allow multicolor detection of genomic loci with high spatial resolution, which provides an avenue for barcoding elements of the human genome in the living state. |
FILED | Friday, March 12, 2021 |
APPL NO | 17/200398 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0696 (20130101) C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 2501/65 (20130101) C12N 2501/70 (20130101) C12N 2510/00 (20130101) C12N 2740/15043 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098382 | Perez et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
ASSIGNEE(S) | University of Marylnd, College Park (College Park, Maryland) |
INVENTOR(S) | Daniel R. Perez (Olney, Maryland); Hongjun Chen (Hyattsville, Maryland); Yibin Cai (Hyattsville, Maryland); Lindomar Jose Pena (College Park, Maryland); Matthew Angel (Greenbelt, Maryland) |
ABSTRACT | Disclosed are compositions and methods comprising one or more recombinant influenza viruses. Recombinant influenza viruses with mutated polymerases and/or rearranged genomes are disclosed. Constructs comprising different influenza nucleic acid sequences are also provided. Methods of inducing protecting immunity with the recombinant influenza viruses are disclosed. Also disclosed are methods of plasmid-free production of influenza virus comprising amplicons comprising one or more of influenza genes. |
FILED | Friday, May 28, 2021 |
APPL NO | 17/333904 |
ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) A61K 2039/70 (20130101) A61K 2039/525 (20130101) A61K 2039/543 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) C12N 2760/16143 (20130101) C12N 2760/16151 (20130101) C12N 2760/16162 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098385 | Sheikh et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Farah Sheikh (La Jolla, California); Jing Zhang (La Jolla, California) |
ABSTRACT | Disclosed herein are methods of treating arrhythmogenic right ventricular cardiomyopathy in a subject, comprising administering a gene therapy construct comprising a connexin 43 sequence, wherein as a result of the administration, connexin 43 levels in at least a portion of the heart are increased. |
FILED | Wednesday, April 29, 2020 |
APPL NO | 16/862326 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) A61K 38/17 (20130101) A61K 48/0058 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/861 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098390 | Slukvin et al. |
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FUNDED BY |
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APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
INVENTOR(S) | Igor Slukvin (Verona, Wisconsin); Akhilesh Kumar (Madison, Wisconsin) |
ABSTRACT | The present invention relates generally to methods and compositions useful for therapeutic vascular tissue engineering. In particular, the present invention provides methods for generating substantially pure populations of vasculogenic cells from human mesenchymal progenitors, and methods and compositions for clinical applications in the field of regenerative medicine. |
FILED | Monday, August 16, 2021 |
APPL NO | 17/403202 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 35/34 (20130101) A61K 35/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0661 (20130101) Original (OR) Class C12N 2500/90 (20130101) C12N 2501/11 (20130101) C12N 2501/15 (20130101) C12N 2501/115 (20130101) C12N 2501/135 (20130101) C12N 2501/165 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) C12N 2506/1346 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098391 | Gupta et al. |
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FUNDED BY |
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APPLICANT(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York) |
ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York) |
INVENTOR(S) | Sanjeev Gupta (Scarsdale, New York); Sriram Bandi (Belleville, New Jersey) |
ABSTRACT | Methods are provided for producing differentiated cells from stem cells, including producing hepatocytes. Compositions thereof are also provided, as are methods of treating a liver disorder. |
FILED | Thursday, March 21, 2019 |
APPL NO | 16/360228 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/407 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/067 (20130101) Original (OR) Class C12N 5/0672 (20130101) C12N 2500/84 (20130101) C12N 2501/999 (20130101) C12N 2502/14 (20130101) C12N 2506/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098427 | Muir et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Peter Muir (Madison, Wisconsin); Susannah Sample (Madison, Wisconsin); John Svaren (Madison, Wisconsin) |
ABSTRACT | Methods for diagnosing propensity to exhibit acquired peripheral neuropathy in dogs are described. The methods and kits test dogs for presence of a disease-associated genomic variant. Presence of the genomic variant indicates an increased likelihood of the dog developing an acquired peripheral neuropathy. This information can be used to guide preemptive clinical treatment of the animal for peripheral neuropathy and to choose dogs for selective breeding programs. |
FILED | Friday, September 16, 2022 |
APPL NO | 17/946613 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098428 | Deihimi et al. |
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FUNDED BY |
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APPLICANT(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
INVENTOR(S) | Safoora Deihimi (Philadelphia, Pennsylvania); Michael Slifker (Philadelphia, Pennsylvania); Wafik S. El-Deiry (Philadelphia, Pennsylvania) |
ABSTRACT | The present disclosure provides methods for identifying subjects having a cancer or tumor that may be susceptible to treatment with a therapeutic agent used to EGFR-related cancer an/or NTRK-related cancer. |
FILED | Monday, February 26, 2018 |
APPL NO | 16/487272 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/5377 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/22 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098433 | Jewett et al. |
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FUNDED BY |
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APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Julius B. Lucks (Evanston, Illinois); Adam D. Silverman (Chicago, Illinois); Khalid K. Alam (Evanston, Illinois) |
ABSTRACT | Disclosed are methods, devices, kits, components, and compositions for detecting a target molecule in a test sample using a cell-free protein synthesis (CFPS) reaction. The methods, devices, kits, components, and compositions may be utilized for detecting target molecules which may include small molecules and/or metabolites of small molecules. The components and compositions used in the disclosed methods, devices, and kits may be dried or lyophilized and may be present or immobilized on a paper substrate, for example, as a paper test article. |
FILED | Monday, August 05, 2019 |
APPL NO | 17/265785 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) C12Q 1/6897 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/184 (20240501) G01N 33/521 (20130101) G01N 33/1826 (20130101) G01N 2430/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099012 | Ly et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Victoria Ly (Santa Cruz, California); Pierre Baudin (Santa Cruz, California); Pattawong Pansodtee (Santa Cruz, California); Erik Jung (Santa Cruz, California); Robert Currie (Santa Cruz, California); David Haussler (Santa Cruz, California); Mircea Teodorescu (Santa Cruz, California) |
ABSTRACT | An imaging system includes an imaging device having a holder configured to hold a cell culture plate with a plurality of wells. The imaging device also includes an imaging assembly having a plurality of imaging units, each of which is configured to image one well of the plurality of wells. The imaging system also includes a storage platform in communication with the imaging device configured to receive a plurality of images from the imaging device. The system further includes a computer in communication with the imaging device and the storage platform. The computer is configured to control the imaging device and to display at least one image of the plurality of images. |
FILED | Friday, May 06, 2022 |
APPL NO | 17/738251 |
ART UNIT | 2485 — Recording and Compression |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 25/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Original (OR) Class G01N 21/6486 (20130101) G01N 2201/021 (20130101) G01N 2201/062 (20130101) Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) Image Data Processing or Generation, in General G06T 7/571 (20170101) G06T 2207/10056 (20130101) G06T 2207/10148 (20130101) G06T 2207/30024 (20130101) G06T 2207/30072 (20130101) Pictorial Communication, e.g Television H04N 5/265 (20130101) H04N 23/62 (20230101) H04N 23/66 (20230101) H04N 23/90 (20230101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099152 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Ge Wang (Loudonville, New York); Mengzhou Li (Troy, New York); David S. Rundle (Butler, Pennsylvania) |
ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
INVENTOR(S) | Ge Wang (Loudonville, New York); Mengzhou Li (Troy, New York); David S. Rundle (Butler, Pennsylvania) |
ABSTRACT | A method for x-ray photon-counting data correction. The method includes generating, by a training data generation module, training input spectral projection data based, at least in part, on a reference spectral projection data. The training input spectral projection data includes at least one of a pulse pileup distortion, a charge splitting distortion, and/or noise. The method further includes training, by a training module, a data correction artificial neural network (ANN) based, at least in part, on training data. The data correction ANN includes a pulse pileup correction ANN, and a charge splitting correction ANN. The training data includes the training input spectral projection data and the reference spectral projection data. |
FILED | Friday, March 25, 2022 |
APPL NO | 17/704520 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/17 (20130101) Original (OR) Class G01T 1/36 (20130101) G01T 1/171 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/045 (20230101) G06N 3/047 (20230101) G06N 3/088 (20130101) G06N 3/126 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12100480 | Rivas et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Manuel A. Rivas (Palo Alto, California); Matthew Woodward Aguirre (Stanford, California) |
ABSTRACT | Methods to determine an individual's propensity or risk for a trait and applications thereof are described. Generally, systems and methods utilize genetic data acquired from an individual to determine their propensity or risk for a set of components that contribute to a trait. Propensity or risk of a trait is determined by assessing propensity or risk for each component of a set of components and the weighted contribution of each component to the trait. |
FILED | Thursday, August 27, 2020 |
APPL NO | 17/005241 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/20 (20190201) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 12096747 | Deng et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Z. Daniel Deng (Richland, Washington); Jun Lu (Richland, Washington); Huidong Li (Richland, Washington); Jayson J. Martinez (Kennewick, Washington); Mitchell J. Myjak (Richland, Washington) |
ABSTRACT | Organism monitoring devices and organism monitoring methods are described. According to one aspect, an organism monitoring device includes a housing configured to be physically associated with an organism to be monitored, an antenna, signal generation circuitry comprising an oscillator configured to generate an oscillation signal, and an output node configured to output the oscillation signal, impedance matching circuitry coupled with the housing, the antenna and the signal generation circuitry, and wherein the impedance matching circuitry is configured to match an impedance of the signal generation circuitry and an impedance of the antenna, and wherein the impedance matching circuitry is further configured to receive the oscillation signal and to provide the oscillation signal to the antenna, and wherein the antenna is configured to emit a wireless signal externally of the organism monitoring device as a result of the provision of the oscillation signal to the input of the antenna. |
FILED | Monday, March 01, 2021 |
APPL NO | 17/189095 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 11/006 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 1/50 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/38 (20130101) H03H 11/28 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/025 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097390 | Sampayan et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Opcondys, Inc. (Manteca, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); Opcondys, Inc. (Manteca, California) |
INVENTOR(S) | Stephen E. Sampayan (Manteca, California); Kristin Cortella Sampayan (Manteca, California); George James Caporaso (East Quogue, California); Yu-Jiuan Chen (Fremont, California); Clifford C. Shang (Livermore, California) |
ABSTRACT | Methods, devices and systems for ultra-high dose radiotherapy are described that rely in-part on active switching control of a photoconductive switch when the accelerator is accelerating charged particles to produce output radiation at desired dose rates. One example method for producing output radiation in a flash radiotherapy system includes receiving, at a particle accelerator, a charged particle beam, where the particle accelerator system also includes a photoconductive switch coupled to the particle accelerator. The photoconductive switch can operate in a linear mode and includes a doped crystalline material that receives a voltage to establish an electric field across the crystalline material. The method includes producing a plurality of voltage pulses by the photoconductive switch in response to receiving light incident on the doped crystalline material, and accelerating the charged particles by the particle accelerator based on the plurality of voltage pulses to produce the output radiation beams for flash radiotherapy. |
FILED | Tuesday, June 06, 2023 |
APPL NO | 18/329899 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1067 (20130101) A61N 5/1071 (20130101) Original (OR) Class A61N 5/1077 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098074 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | YuHuang Wang (Laurel, Maryland); Xiyuan Cheng (Greenbelt, Maryland); Ayman Alibrahim (College Park, Maryland) |
ABSTRACT | A method of producing a carbon nanotube may include heating a convergent flow nozzle and a flow chamber of a carbon nanotube reactor, flowing a vaporized reactant stream through the nozzle and collecting a carbon nanotube product from an outlet of a heated flow chamber disposed downstream of the heated convergent flow nozzle. The vaporized reactant stream may include a carbon nanotube nucleation carbon source, a carbon nanotube growth carbon source, and a carbon nanotube catalyst precursor. The nozzle may have a nozzle contraction ratio of from 3:1 to 300:1. |
FILED | Friday, May 20, 2022 |
APPL NO | 17/749696 |
ART UNIT | 1759 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/162 (20170801) Original (OR) Class C01B 2202/30 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/02 (20130101) C01P 2002/82 (20130101) C01P 2002/85 (20130101) C01P 2002/88 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098079 | Beach et al. |
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FUNDED BY |
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APPLICANT(S) | Starfire Energy (Denver, Colorado) |
ASSIGNEE(S) | STARFIRE ENERGY (Denver, Colorado) |
INVENTOR(S) | Joseph D. Beach (Aurora, Colorado); Jonathan D. Kinter (Aurora, Colorado); Adam W. Welch (Aurora, Colorado) |
ABSTRACT | A chemical reactor that combines a pressure vessel, heat exchanger, heater, and catalyst holder into a single device is disclosed. The chemical reactor described herein reduces the cost of the reactor and reduces its parasitic heat losses. The disclosed chemical reactor is suitable for use in ammonia (NH3) synthesis. |
FILED | Wednesday, February 16, 2022 |
APPL NO | 17/672843 |
ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/0278 (20130101) B01J 8/0285 (20130101) B01J 12/007 (20130101) B01J 19/0013 (20130101) B01J 2208/065 (20130101) B01J 2219/00135 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/0411 (20130101) C01C 1/0417 (20130101) Original (OR) Class Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 9/04 (20130101) F28D 9/0093 (20130101) F28D 2021/0022 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098171 | O'Malley et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
INVENTOR(S) | Michelle A. O'Malley (Santa Barbara, California); Igor A. Podolsky (Goleta, California); Susanna Seppala (Santa Barbara, California) |
ABSTRACT | The present invention provides for a hybrid sugar transporter having an altered sugar transporter activity and comprising at least a first transmembrane domain (TMD) from a first sugar transporter and a second TMD from a second sugar transporter, wherein the first sugar transporter and the second sugar transporter are heterologous to each other. |
FILED | Friday, December 10, 2021 |
APPL NO | 17/548410 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/37 (20130101) Original (OR) Class C07K 2319/03 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098186 | Harmon et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Brooke Nicole Harmon (Livermore, California); Le Thanh Mai Pham (Berkeley, California); Yooli Kim Light (Pleasanton, California); Christine Elizabeth Thatcher (Oakland, California); Maxwell Stefan (Pleasanton, California) |
ABSTRACT | Provided herein are asymmetric biparatopic neutralizing nanobody-based antibodies which engage SARS-2 spike in at least two independent epitopes. Several biparatopic constructs showed synergy in neutralizing viral infection of cells. Data also showed that single biparatopic constructs are more effective than the combination of the parental monotopic constructs were at neutralization. The nanobodies that were identified in an initial screen of a large and highly diverse library bind to a single epitope that overlaps with the ACE2 binding site. |
FILED | Thursday, June 30, 2022 |
APPL NO | 17/854735 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098200 | Harmon et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Brooke Nicole Harmon (Livermore, California); Maxwell Stefan (Pleasanton, California); Jennifer Schwedler (Livermore, California); Christopher Sumner (Livermore, California); Yooli Kim Light (Pleasanton, California); Catherine Margaret Mageeney (Livermore, California) |
ABSTRACT | Provided herein are single domain antibodies (sdAbs) configured for passing the blood brain barrier in a human or mammal brain. Methods of using such sdAbs are also described herein, such as methods of binding to brain cells, binding with and transporting other sdAbs with beneficial functionalities, binding to and transporting biochemical or pharmaceutical species with beneficial functionalities, and treating, diagnosing, or prophylactically treating a disease, malignancy, or condition. |
FILED | Wednesday, October 12, 2022 |
APPL NO | 17/964213 |
ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/28 (20130101) Original (OR) Class C07K 2317/565 (20130101) C07K 2317/569 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098283 | Liao et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Chen Liao (Westmont, Illinois); Trevor L. Dzwiniel (Carol Stream, Illinois); Kewel Liu (Aurora, Illinois) |
ABSTRACT | Described herein are borate salts useful as additives, binders, and electrolyte salts for solid state lithium ion batteries. In particular, the borate salts of Formula (I), Formula (II) and Formula (III) as described herein: can be bound to an existing polymer to provide polymeric binders for ceramic solid state electrolytes that are themselves capable of ion transport independent of the ceramic. |
FILED | Friday, February 24, 2023 |
APPL NO | 18/114055 |
ART UNIT | 1625 — Organic Chemistry |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 79/08 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/37 (20130101) Compositions of Macromolecular Compounds C08L 85/04 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/622 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) H01M 2300/0091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098467 | He et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Ting He (Idaho Falls, Idaho); Dong Ding (Idaho Falls, Idaho); Wei Wu (Idaho Falls, Idaho) |
ABSTRACT | A method of producing hydrogen gas comprises introducing gaseous water to an electrolysis cell comprising a positive electrode, a negative electrode, and a proton-conducting membrane between the positive electrode and the negative electrode. The proton-conducting membrane comprises an electrolyte material having an ionic conductivity greater than or equal to about 10−2 S/cm at one or more temperatures within a range of from about 150° C. to about 650° C. The gaseous water is decomposed using the electrolysis cell. A hydrogen gas production system and an electrolysis cell are also described. |
FILED | Wednesday, October 13, 2021 |
APPL NO | 17/450810 |
ART UNIT | 1759 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) Original (OR) Class C25B 1/042 (20210101) C25B 1/044 (20210101) C25B 9/23 (20210101) C25B 9/73 (20210101) C25B 11/047 (20210101) C25B 13/05 (20210101) C25B 13/07 (20210101) C25B 15/021 (20210101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098469 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Drexel University (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Yawei Li (Shanxi, China PRC); Kenneth Charles Neyerlin (Arvada, Colorado); Joshua David Snyder (Sparks, Maryland) |
ABSTRACT | The present disclosure relates to a composition that includes a solid, a first layer of an ionic liquid including an anion and a cation, a second layer including an ionically conductive ionomer, and a catalyst including a metal positioned on the solid, where the ionic liquid forms a first layer on the solid, the first layer is positioned between the second layer and the solid, and the catalyst is positioned between the solid and the first layer. |
FILED | Tuesday, September 28, 2021 |
APPL NO | 17/487108 |
ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 11/053 (20210101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/86 (20130101) H01M 4/88 (20130101) H01M 8/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098475 | Grotjohn et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan); Fraunhofer USA (Plymouth, Michigan) |
ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan); Fraunhofer USA (Plymouth, Michigan) |
INVENTOR(S) | Timothy A. Grotjohn (Okemos, Michigan); Ramon Diaz (East Lansing, Michigan); Aaron Hardy (East Lansing, Michigan) |
ABSTRACT | The disclosure relates to large area single crystal diamond (SCD) surfaces and substrates, and their methods of formation. Typical large area substrates can be at least about 25 mm, 50 mm, or 100 mm in diameter or square edge length, and suitable thicknesses can be about 100 μm to 1000 μm. The large area substrates have a high degree of crystallographic alignment. The large area substrates can be used in a variety of electronics and/or optics applications. Methods of forming the large area substrates generally include lateral and vertical growth of SCD on spaced apart and crystallographically aligned SCD seed substrates, with the individual SCD growth layers eventually merging to form a composite SCD layer of high quality and high crystallographic alignment. A diamond substrate holder can be used to crystallographically align the SCD seed substrates and reduce the effect of thermal stress on the formed SCD layers. |
FILED | Thursday, May 16, 2019 |
APPL NO | 17/055943 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/04 (20130101) C30B 25/08 (20130101) C30B 25/12 (20130101) C30B 25/16 (20130101) C30B 25/20 (20130101) C30B 25/025 (20130101) Original (OR) Class C30B 29/04 (20130101) C30B 29/68 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099048 | Deng et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Z. Daniel Deng (Richland, Washington); Yang Yang (Richland, Washington); Jun Lu (Richland, Washington); Huidong Li (Richland, Washington); Jayson J. Martinez (Kennewick, Washington); Brett D. Pflugrath (West Richland, Washington) |
ABSTRACT | Aquatic organism monitoring devices and aquatic organism monitoring methods are described. According to one aspect, a monitoring device includes a housing configured to be physically associated with an aquatic organism, environmental circuitry configured to generate a first output indicative of at least one environmental parameter of an environment of the organism, behavioral circuitry coupled with the housing and configured to generate a second output indicative of at least one behavioral parameter of the organism, physiological circuitry coupled with the housing and configured to generate a third output indicative of at least one physiological parameter of the organism, and a transmitter configured to transmit an acoustic signal externally of the housing, and wherein the acoustic signal includes information regarding one or more of the at least one environmental parameter, the at least one behavioral parameter, and the at least one physiological parameter. |
FILED | Wednesday, November 18, 2020 |
APPL NO | 16/951251 |
ART UNIT | 2896 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 11/006 (20130101) A01K 61/90 (20170101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/186 (20130101) Original (OR) Class G01N 33/1886 (20130101) Technologies for Adaptation to Climate Change Y02A 40/81 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099153 | Goetz et al. |
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FUNDED BY |
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APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Kathleen C. Goetz (Knoxville, Tennessee); Mustafa S. Cetiner (Lexington, Massachusetts) |
ABSTRACT | A detector for generating an electrical current that is proportional to a flux of neutrons includes a neutron sensitive emitter, a conductive collector, an insulator between the neutron-sensitive emitter and the collector, an electrical connection to the neutron sensitive emitter, and an electrical connection to the conductive collector. The neutron sensitive emitter includes an emitter material with no more than 2 stable isotopes, and which upon impact by a neutron having an energy of from 100 keV to 1000 keV will generate electrons in proportion to the flux of neutrons in less than 10 minutes, and any generated electrons not generated in less than 10 minutes will be generated in no less than 30 days. A method of detecting neutrons generated by a nuclear reactor is also disclosed. |
FILED | Monday, October 25, 2021 |
APPL NO | 17/510044 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Measurement of Nuclear or X-radiation G01T 3/006 (20130101) Original (OR) Class Nuclear Reactors G21C 17/102 (20130101) G21C 17/108 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099269 | Chatterjee et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Bikramjit Chatterjee (Livermore, California); Lars F. Voss (Livermore, California); Clint Frye (Oakland, California) |
ABSTRACT | An optically addressable light valve comprises a first transparent conductor layer, a layer of liquid crystal, and a photoconductor comprising an ultrawide band gap (UWBG) semiconductor. The liquid crystal is between the first transparent conductor layer and the semiconductor photoconductor. The optically addressable light valve is configured to apply a voltage across the liquid crystal and the UWBG semiconductor. A second transparent conductor may be formed in the UWBG semiconductor in some configurations, and the voltage may be applied across the first and second transparent conductor. |
FILED | Friday, December 15, 2023 |
APPL NO | 18/542455 |
ART UNIT | 2871 — Optics |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/13439 (20130101) G02F 1/133385 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099402 | Baronne |
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FUNDED BY |
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APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
INVENTOR(S) | Christopher Baronne (Allen, Texas) |
ABSTRACT | Devices and techniques for parking threads in a barrel processor for managing hazard clearing are described herein. A barrel processor includes hazard management circuitry that is used to receive an indication of an instruction executing in a compute pipeline of the barrel processor, the instruction having encountered a hazard and unable to progress through the compute pipeline; store the indication of the instruction in a hazard memory; receive a signal indicating that the hazard has cleared; and cause the instruction to be rescheduled at the beginning of the compute pipeline in response to the signal. |
FILED | Monday, August 29, 2022 |
APPL NO | 17/897926 |
ART UNIT | 2113 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 9/3861 (20130101) G06F 11/0721 (20130101) G06F 11/0793 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099407 | Sullivan et al. |
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FUNDED BY |
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APPLICANT(S) | NVIDIA Corp. (Santa Clara, California) |
ASSIGNEE(S) | NVIDIA CORP. (Santa Clara, California) |
INVENTOR(S) | Michael Sullivan (Austin, Texas); Siva Kumar Sastry Hari (Sunnyvale, California); Brian Matthew Zimmer (Mountain View, California); Timothy Tsai (Santa Clara, California); Stephen W. Keckler (Austin, Texas) |
ABSTRACT | An error reporting system utilizes a parity checker to receive data results from execution of an original instruction and a parity bit for the data. A decoder receives an error correcting code (ECC) for data resulting from execution of a shadow instruction of the original instruction, and data error correction is initiated on the original instruction result on condition of a mismatch between the parity bit and the original instruction result, and the decoder asserting a correctable error in the original instruction result. |
FILED | Thursday, May 05, 2022 |
APPL NO | 17/737374 |
ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Electric Digital Data Processing G06F 9/30029 (20130101) G06F 9/30116 (20130101) G06F 11/102 (20130101) Original (OR) Class G06F 11/0772 (20130101) G06F 11/1044 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099571 | Yan et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | GE INFRASTRUCTURE TECHNOLOGY LLC (Greenville, South Carolina) |
INVENTOR(S) | Weizhong Yan (Clifton Park, New York); Lalit Keshav Mestha (North Colonie, New York); Daniel Francis Holzhauer (Burnt Hills, New York) |
ABSTRACT | Heterogeneous monitoring nodes may each generate a series of monitoring node values over time associated with operation of an industrial asset. An offline abnormal state detection model creation computer may receive the series of monitoring node values and perform a feature extraction process using a multi-modal, multi-disciplinary framework to generate an initial set of feature vectors. Then feature dimensionality reduction is performed to generate a selected feature vector subset. The model creation computer may derive digital models through a data-driven machine learning modeling method, based on input/output variables identified by domain experts or by learning from the data. The system may then automatically generate domain level features based on a difference between sensor measurements and digital model output. A decision boundary may then be automatically calculated and output for an abnormal state detection model based on the selected feature vector subset and the plurality of derived generated domain level features. |
FILED | Monday, May 21, 2018 |
APPL NO | 15/984896 |
ART UNIT | 2124 — AI & Simulation/Modeling |
CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/027 (20130101) G05B 23/024 (20130101) G05B 23/0254 (20130101) Electric Digital Data Processing G06F 18/213 (20230101) Original (OR) Class G06F 2218/08 (20230101) Computer Systems Based on Specific Computational Models G06N 3/008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099867 | Puthoor et al. |
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FUNDED BY |
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APPLICANT(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
ASSIGNEE(S) | Advanced Micro Devices, Inc. (Santa Clara, California) |
INVENTOR(S) | Sooraj Puthoor (Austin, Texas); Joseph Gross (Austin, Texas); Xulong Tang (State College, Pennsylvania); Bradford Michael Beckmann (Redmond, Washington) |
ABSTRACT | Systems, apparatuses, and methods for implementing a multi-kernel wavefront scheduler are disclosed. A system includes at least a parallel processor coupled to one or more memories, wherein the parallel processor includes a command processor and a plurality of compute units. The command processor launches multiple kernels for execution on the compute units. Each compute unit includes a multi-level scheduler for scheduling wavefronts from multiple kernels for execution on its execution units. A first level scheduler creates scheduling groups by grouping together wavefronts based on the priority of their kernels. Accordingly, wavefronts from kernels with the same priority are grouped together in the same scheduling group by the first level scheduler. Next, the first level scheduler selects, from a plurality of scheduling groups, the highest priority scheduling group for execution. Then, a second level scheduler schedules wavefronts for execution from the scheduling group selected by the first level scheduler. |
FILED | Wednesday, May 30, 2018 |
APPL NO | 15/993061 |
ART UNIT | 2196 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 9/4881 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12100479 | Vuyisich et al. |
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FUNDED BY |
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APPLICANT(S) | BlueDot LLC (Bellevue, Washington); TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | BLUEDOT, LLC (Bellevue, Washington); TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Momchilo Vuyisich (Los Alamos, New Mexico); Jason Gans (Los Alamos, New Mexico); Niels Klitgord (Poway, California); Po-E Li (Los Alamos, New Mexico); Patrick Chain (Los Alamos, New Mexico) |
ABSTRACT | Provided are methods and systems for metagenomic analysis. Methods involve generating libraries and databases of taxonomic signatures informative of taxonomic information in a heterogeneous microbial sample. Methods also include identification of microorganisms and biochemical activities in the sample, including identification at a plurality of taxonomic levels. |
FILED | Thursday, March 01, 2018 |
APPL NO | 16/490288 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6874 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 10/00 (20190201) G16B 20/20 (20190201) Original (OR) Class G16B 30/10 (20190201) G16B 30/20 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12100520 | Gates |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
INVENTOR(S) | David Gates (Princeton, New Jersey) |
ABSTRACT | Disclosed herein is a stellarator comprising two sets of coils, namely a set of encircling coils which encircle the plasma axis, and a set of shaping coils which do not encircle any other coil or the plasma. In some embodiments, the encircling coils include a structural element to maintain their shape under magnetic forces. In some embodiments, the shaping coils are mounted onto one or more structural elements which, together with the shaping coils, constitute a field shaping unit. Also disclosed is a controller which may modify the electrical current flowing in one or more subsets of the coils in order to achieve target plasma parameters. Also disclosed is a method of designing a set of shaping coils by discretizing a surface dipole or current potential distribution. |
FILED | Thursday, January 18, 2024 |
APPL NO | 18/415840 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Fusion Reactors G21B 1/055 (20130101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 6/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12100521 | Carter et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho); University of Idaho (Moscow, Idaho) |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho); University of Idaho (Moscow, Idaho) |
INVENTOR(S) | John P. Carter (Idaho Falls, Idaho); Richard Christensen (Idaho Falls, Idaho) |
ABSTRACT | A flow control device configured to be positioned in a reactor core. The flow control device including a central shaft and at least one blade extending helically from the central shaft. A nuclear reactor and related systems and methods are also disclosed. |
FILED | Wednesday, September 28, 2022 |
APPL NO | 17/936248 |
ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Nuclear Reactors G21C 15/12 (20130101) Original (OR) Class G21C 19/28 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12100523 | Callaway et al. |
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FUNDED BY |
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APPLICANT(S) | NuScale Power, LLC (Portland, Oregon) |
ASSIGNEE(S) | NuScale Power, LLC (Corvallis, Oregon) |
INVENTOR(S) | Allyson Callaway (Corvallis, Oregon); Ben Bristol (Philomath, Oregon); Kenneth Rooks (Corvallis, Oregon); Larry Linik (Corvallis, Oregon) |
ABSTRACT | A nuclear power system includes a reactor vessel that includes a reactor core mounted therein. The reactor core includes nuclear fuel assemblies configured to generate a nuclear fission reaction. The nuclear power system further includes a chemical injection system configured to inject a chemical into the reactor vessel and remove the chemical from the reactor vessel, and a control system communicably coupled to the chemical injection system and configured to control a power output of the nuclear fission reaction. For example, the control system can determine that the power output is greater than an upper value of a range or less than a lower value of the range and, based on the determination, adjust an amount of the chemical injected into or removed from the reactor vessel by the chemical injection system to adjust the power output. |
FILED | Thursday, June 02, 2022 |
APPL NO | 17/831083 |
ART UNIT | 2628 — Selective Visual Display Systems |
CURRENT CPC | Methods of Steam Generation; Steam Boilers F22B 35/004 (20130101) Nuclear Reactors G21C 1/028 (20130101) G21C 7/08 (20130101) G21C 7/12 (20130101) Original (OR) Class G21C 7/22 (20130101) G21C 7/24 (20130101) G21C 9/02 (20130101) G21C 9/033 (20130101) G21C 13/022 (20130101) Nuclear Power Plant G21D 1/006 (20130101) G21D 3/02 (20130101) G21D 3/14 (20130101) G21D 3/16 (20130101) G21D 3/18 (20130101) G21D 5/08 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12100527 | Blanton et al. |
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FUNDED BY |
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APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
INVENTOR(S) | Paul S. Blanton (Aiken, South Carolina); Zenghu Han (Woodridge, Illinois); Yung Y. Liu (Hinsdale, Illinois); Ronald B. Pope (Waynesboro, Pennsylvania); James M. Shuler (Germantown, Maryland) |
ABSTRACT | The invention provides a containment structure, the containment structure comprising a vessel with an upwardly facing opening defining a periphery; a lid in rotatable and slidable communication with the periphery; and a plurality of rods contained within the lid and in slidable communication with the periphery. Also provided is a method for sealing and unsealing a containment vessel defining a body with a longitudinal axis and a lid, the method comprising simultaneously moving the lid parallel to the longitudinal axis and orthogonal to the longitudinal axis. |
FILED | Friday, February 18, 2022 |
APPL NO | 17/675604 |
ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
CURRENT CPC | Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/005 (20130101) G21F 5/12 (20130101) Original (OR) Class G21F 9/36 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12100560 | Chowdhury et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Shajjad Chowdhury (Oak Ridge, Tennessee); Raj Sahu (Mountain View, California); Emre Gurpinar (Knoxville, Tennessee); Burak Ozpineci (Oak Ridge, Tennessee) |
ABSTRACT | A capacitor packaging having a central termination and three or more capacitors (or groups of capacitors) arranged about the central termination. The electrical flow paths between the termination and the capacitors or groups of capacitors are of substantially the same length. The capacitors or groups of capacitors may be arranged in a generally circular pattern with the termination centered on the center. The termination may include first and second terminals. The capacitors may be mounted to a printed circuit board (“PCB”) with traces on opposite surfaces of the PCB providing electrical flow paths from the terminals to opposite legs of the capacitors. The capacitor packaging may include a primary PCB with a first circular arrangement of capacitors and a secondary PCB with a second circular arrangement of capacitors. The capacitors may be sandwiched between the PCBs with the second arrangement of capacitors disposed concentrically inwardly of the first arrangement. |
FILED | Thursday, May 12, 2022 |
APPL NO | 17/742690 |
ART UNIT | 2848 — Electrical Circuits and Systems |
CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 4/38 (20130101) Original (OR) Class H01G 4/232 (20130101) H01G 4/1245 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/162 (20130101) H05K 2201/09227 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12100800 | Ye et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Jianchao Ye (Tracy, California); Jose Ali Espitia (Livermore, California); John Miller (Walnut Creek, California); Marissa Wood (Oakland, California) |
ABSTRACT | A product includes a solid state electrolyte particle coated with a coating consisting essentially of metal oxide. A method includes depositing a coating on a solid state electrolyte particle by atomic layer deposition. A method includes fabricating a product using a plurality of solid state electrolyte particles coated with a coating consisting essentially of metal oxide. |
FILED | Thursday, April 15, 2021 |
APPL NO | 17/231886 |
ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 25/006 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2004/84 (20130101) C01P 2006/40 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/40 (20130101) C23C 16/45555 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2004/028 (20130101) H01M 2300/0077 (20130101) H01M 2300/0094 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12100966 | Lethellier et al. |
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FUNDED BY |
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APPLICANT(S) | Wireless Advanced Vehicle Electrification, LLC (Salt Lake City, Utah) |
ASSIGNEE(S) | Wireless Advanced Vehicle Electrification, LLC (Salt Lake City, Utah) |
INVENTOR(S) | Patrice Lethellier (Salt Lake City, Utah); Kelly Wardell (Stansbury Park, Utah); Adeel Zaheer (West Valley, Utah) |
ABSTRACT | Described herein is a structure, the implementation of which may result in optimization of power transfer within a wireless power transfer pad. Such a structure comprises two planes in parallel that each comprise multiple windings. Additionally, the structure may include two magnetic structures that each pass through the centers of the multiple windings of one of the respective planes. In some embodiments, a magnetic structure may include a main section and two vertical sections. In some cases, the magnetic structure may further include at least one side section that connects with a vertical section. |
FILED | Wednesday, December 15, 2021 |
APPL NO | 17/551743 |
ART UNIT | 2836 — Electrical Circuits and Systems |
CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/005 (20200101) Original (OR) Class H02J 50/12 (20160201) H02J 50/40 (20160201) H02J 50/90 (20160201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12101366 | Palmer |
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FUNDED BY |
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APPLICANT(S) | TRIAD National Security, LLC. (Los Alamos, New Mexico) |
ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | David Palmer (Los Alamos, New Mexico) |
ABSTRACT | Techniques for framing data in various data transmission contexts are described. A data framing technique may include a transmitter sending a data stream including repeating bits in alternating forward and reverse order. A receiver of the data stream may fold the data stream, and correlate portions of the folded data stream for purposes of validating the data stream and/or identifying an ID in the data stream. In at least some instances, once the receiver validates the data stream, the receiver may accept payload accompanying the data stream. |
FILED | Monday, July 10, 2023 |
APPL NO | 18/219962 |
ART UNIT | 2465 — Multiplex and VoIP |
CURRENT CPC | Transmission H04B 7/24 (20130101) H04B 7/216 (20130101) Multiplex Communication H04J 13/10 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/36 (20130101) H04L 65/70 (20220501) Original (OR) Class H04L 69/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12101367 | Palmer |
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FUNDED BY |
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APPLICANT(S) | TRIAD National Security, LLC. (Los Alamos, New Mexico) |
ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | David Palmer (Los Alamos, New Mexico) |
ABSTRACT | A device includes a processor configured to generate a palindromic sequence associated with a unique identifier (ID) associated with the device, and provide the generated palindromic sequence to a transmitter, the palindromic sequence including forward order of bits, reverse order of bits and a spacer bit. The device further includes the transmitter configured to repeatedly transmit the generated palindromic. |
FILED | Monday, July 10, 2023 |
APPL NO | 18/219976 |
ART UNIT | 2465 — Multiplex and VoIP |
CURRENT CPC | Transmission H04B 7/24 (20130101) H04B 7/216 (20130101) Multiplex Communication H04J 13/10 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/36 (20130101) H04L 65/70 (20220501) Original (OR) Class H04L 69/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12101398 | Lukens et al. |
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FUNDED BY |
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APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
INVENTOR(S) | Joseph M. Lukens (Knoxville, Tennessee); Pavel Lougovski (Knoxville, Tennessee) |
ABSTRACT | Methods of quantum key distribution include receiving a frequency bin photon at a location, selecting a frequency bin photon quantum key distribution measurement basis, with a quantum frequency processor, performing a measurement basis transformation on the received frequency bin photon so that the frequency bin photon is measurable in the selected frequency bin photon quantum key distribution measurement basis, and detecting the frequency bin photon in the selected quantum key distribution measurement basis and assigning a quantum key distribution key value based on the detection to a portion of a quantum key distribution key. Apparatus and methods for encoding, decoding, transmitting, and receiving frequency bin photons are disclosed. |
FILED | Thursday, June 29, 2023 |
APPL NO | 18/216450 |
ART UNIT | 2435 — Cryptography and Security |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0858 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12101870 | Kobernik et al. |
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FUNDED BY |
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APPLICANT(S) | SHINE Technologies, LLC (Janesville, Wisconsin) |
ASSIGNEE(S) | SHINE Technologies, LLC (Janesville, Wisconsin) |
INVENTOR(S) | Arne Kobernik (Monona, Wisconsin); Carl Sherven (Monona, Wisconsin); Casey Lamers (Monona, Wisconsin); Chris Seyfert (Monona, Wisconsin); Evan Sengbusch (Monona, Wisconsin); Gabriel Becerra (Monona, Wisconsin); Jin Lee (Monona, Wisconsin); Logan Campbell (Monona, Wisconsin); Mark Thomas (Monona, Wisconsin); Michael Taylor (Monona, Wisconsin); Preston Barrows (Monona, Wisconsin); Ross Radel (Monona, Wisconsin); Tye Gribb (Monona, Wisconsin) |
ABSTRACT | Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes. |
FILED | Monday, January 09, 2023 |
APPL NO | 18/094724 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/08 (20130101) H01J 37/32082 (20130101) H01J 41/04 (20130101) H01J 41/14 (20130101) Spark Gaps; Overvoltage Arresters Using Spark Gaps; Sparking Plugs; Corona Devices; Generating Ions to be Introduced into Non-enclosed Gases H01T 23/00 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 31/26 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) H05H 1/54 (20130101) H05H 1/4622 (20210501) H05H 3/06 (20130101) H05H 5/04 (20130101) H05H 6/00 (20130101) H05H 7/22 (20130101) Original (OR) Class H05H 9/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12101948 | Hammond et al. |
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FUNDED BY |
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APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); SolarWindow Technologies, Inc. (Scottsdale, Arizona) |
ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); SolarWindow Technologies, Inc. (Scottsdale, Arizona) |
INVENTOR(S) | Scott R. Hammond (Wheat Ridge, Colorado); Marinus Franciscus Antonius Maria van Hest (Golden, Colorado) |
ABSTRACT | Systems and methods for organic semiconductor devices with sputtered contact layers are provided. In one embodiment, an organic semiconductor device comprises: a first contact layer comprising a first sputter-deposited transparent conducting oxide; an electron transport layer interfacing with the first contact layer; a second contact layer comprising a second sputter-deposited transparent conducting oxide; a hole transport layer interfacing with the second contact layer; and an organic semiconductor active layer having a first side facing the electron transport layer and an opposing second side facing the hole transport layer; wherein either the electron transport layer or the hole transport layer comprises a buffering transport layer. |
FILED | Thursday, July 13, 2023 |
APPL NO | 18/351880 |
ART UNIT | 2818 — Semiconductors/Memory |
CURRENT CPC | Organic electric solid-state devices H10K 30/82 (20230201) Original (OR) Class H10K 50/11 (20230201) H10K 50/15 (20230201) H10K 50/16 (20230201) H10K 50/816 (20230201) H10K 50/828 (20230201) H10K 71/16 (20230201) H10K 71/60 (20230201) H10K 2102/101 (20230201) H10K 2102/103 (20230201) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12102005 | Schwede et al. |
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FUNDED BY |
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APPLICANT(S) | Spark Thermionics, Inc. (Berkeley, California) |
ASSIGNEE(S) | Spark Thermionics, Inc. (Berkeley, California) |
INVENTOR(S) | Jared William Schwede (Berkeley, California); Lucas Heinrich Hess (Berkeley, California) |
ABSTRACT | A thermionic energy converter, preferably including an anode and a cathode. An anode of a thermionic energy converter, preferably including an n-type semiconductor, one or more supplemental layers, and an electrical contact. A method for work function reduction and/or thermionic energy conversion, preferably including inputting thermal energy to a thermionic energy converter, illuminating an anode of the thermionic energy converter, thereby preferably reducing a work function of the anode, and extracting electrical power from the system. |
FILED | Wednesday, November 23, 2022 |
APPL NO | 17/993195 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 45/00 (20130101) Electric solid-state devices not otherwise provided for H10N 10/13 (20230201) Original (OR) Class H10N 10/851 (20230201) H10N 10/853 (20230201) H10N 10/855 (20230201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP36135 | McMahon et al. |
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FUNDED BY |
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APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
INVENTOR(S) | Bernard G. McMahon (Coon Rapids, Minnesota); William Berguson (Duluth, Minnesota) |
ABSTRACT | The invention is a new and distinct variety of male Populus tree named ‘NextGen’ that is characterized by its superior to above average field growth performance, its excellent to above average rooting rate, its disease resistance to foliar rusts (Melampsora sp.), leaf spots (Marssonina sp.) and stem cankers (Septoria sp.), its vigorous vegetative growth and production in nursery stoolbeds, its cold hardiness for overwintering and surviving in Minnesota with no frost damage, its wide-spread superior growth performance in many test locations (ie: MN, MI, WI, IA, IN, NY, etc); able to be considered “geo-robust” after years of testing, its replicated growth testing and evidence of promising performance and evaluation in phytoremediation research testing and applications, and its male flowers that do not produce seeds. |
FILED | Wednesday, November 22, 2023 |
APPL NO | 18/517841 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/218 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 12096999 | Frederick et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
INVENTOR(S) | Tom Frederick (Lincoln, Nebraska); Eric Markvicka (Brush, Colorado); Shane Farritor (Lincoln, Nebraska); Dmitry Oleynikov (Omaha, Nebraska) |
ABSTRACT | The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices. |
FILED | Thursday, August 04, 2022 |
APPL NO | 17/880823 |
ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) A61B 18/082 (20130101) A61B 18/1445 (20130101) A61B 34/30 (20160201) Original (OR) Class A61B 2017/00398 (20130101) A61B 2017/00407 (20130101) A61B 2017/00477 (20130101) A61B 2018/00595 (20130101) A61B 2018/1253 (20130101) A61B 2018/1422 (20130101) A61B 2034/305 (20160201) A61B 2217/005 (20130101) A61B 2217/007 (20130101) A61B 2218/002 (20130101) A61B 2218/007 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/046 (20130101) B25J 9/0087 (20130101) B25J 9/102 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097015 | Boamah et al. |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois); California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Mavis D. Boamah (Evanston, Illinois); Franz M. Geiger (Evanston, Illinois); Thomas F. Miller, III (South Pasadena, California); Jeongmin Kim (Pasadena, California) |
ABSTRACT | Energy harvesting devices and methods for converting the mechanical energy of a flowing ionic solution, such as rainwater or seawater, into electric energy are provided. The energy harvesting devices include an electric current generating device that includes a metal layer and an amphoteric metal oxide film disposed over a surface of the metal layer. By moving an electric double layer across the surface of the amphoteric metal oxide film, an electric current is generated in the metal layer. |
FILED | Tuesday, September 17, 2019 |
APPL NO | 17/276684 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/026 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) H02N 11/002 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097029 | Shanechi |
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FUNDED BY |
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APPLICANT(S) | University of Southern California (Los Angeles, California) |
ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
INVENTOR(S) | Maryam Shanechi (Los Angeles, California) |
ABSTRACT | A method for decoding mood or other neuropsychiatric states from large-scale brain activity includes receiving, by a processor, large-scale brain activity signals from an electrode assembly coupled to a subject. The method includes continuously and automatically decoding a neuropsychiatric state of the subject from the large-scale brain activity signals received from a predictive network subset of brain sites coupled to the electrode assembly, contemporaneously with the receiving. The method includes providing a signal indicative of the neuropsychiatric state. A method for adaptive tracking of large-scale brain network activity includes characterizing, by one or more computers, a time-variant linear state-space model predictive of a brain state, at least in part by updating estimates of time-varying covariance matrices at time steps. The method includes tracking large-scale brain network activity in a subject using an electrode array and continuously and automatically estimating the subject's brain state contemporaneously with the characterizing and tracking. |
FILED | Tuesday, July 10, 2018 |
APPL NO | 16/031925 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/16 (20130101) A61B 5/165 (20130101) Original (OR) Class A61B 5/316 (20210101) A61B 5/369 (20210101) A61B 5/4803 (20130101) A61B 5/7267 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097246 | Labhasetwar et al. |
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FUNDED BY |
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APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
INVENTOR(S) | Vinod Labhasetwar (Cleveland, Ohio); Hayder H. Jaffer (Cleveland, Ohio) |
ABSTRACT | The invention is directed to a method of treating a spinal cord injury, a neurodegenerative disease or a neuronal injury in an individual in need thereof comprising administering an effective amount of superoxide dismutase (SOD) and catalase to the individual, wherein the superoxide dismutase and the catalase are encapsulated in one or more nanoparticles that release the SOD and catalase upon administration. Another aspect of the invention is directed to compositions comprising superoxide dismutase (SOD) and catalase encapsulated in one or more nanoparticles. |
FILED | Wednesday, June 22, 2022 |
APPL NO | 17/846130 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/19 (20130101) A61K 9/5153 (20130101) A61K 38/44 (20130101) A61K 38/446 (20130101) Original (OR) Class Enzymes C12Y 111/01006 (20130101) C12Y 115/01001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097269 | Kundra et al. |
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FUNDED BY |
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APPLICANT(S) | Vikas Kundra (Missouri City, Texas); James A. Bankson (Pearland, Texas); Ananth Annapragada (Manvel, Texas); Ketan B. Ghaghada (Houston, Texas); Murali K. Ravoori (Pearland, Texas) |
ASSIGNEE(S) | |
INVENTOR(S) | Vikas Kundra (Missouri City, Texas); James A. Bankson (Pearland, Texas); Ananth Annapragada (Manvel, Texas); Ketan B. Ghaghada (Houston, Texas); Murali K. Ravoori (Pearland, Texas) |
ABSTRACT | Provided herein are nanoparticle-based gadolinium (Gd) agents which may be used, e.g., in T1-weighted MR imaging (MRI). In various embodiments, dual-Gd liposomal agents are provided which contain both core-encapsulated Gd as well as surface-conjugated Gd. In various embodiments, these agents were observed to deliver a higher concentrations of Gd and result in substantial improvements in signal to noise ratios and contrast to noise ratios. Also provided are methods for in vivo imaging and/or treating diseases such as cancer or tumor in a subject. |
FILED | Thursday, October 27, 2011 |
APPL NO | 13/283272 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 49/14 (20130101) A61K 49/1812 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097304 | Alghazali et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
INVENTOR(S) | Karrer M. Alghazali (Little Rock, Arkansas); Zeid A. Nima (Little Rock, Arkansas); Alexandru S. Biris (Little Rock, Arkansas) |
ABSTRACT | A method for forming a biocompatible structure includes the steps of forming a layered structure having alternatively disposed first layers and second layers, where the first layers includes at least one polymer and first particles, and the second layers includes second particles; and treating the layered structure with a washing solvent to form the biocompatible structure, where the first particles are solvable in the washing solvent. |
FILED | Wednesday, May 10, 2017 |
APPL NO | 15/591728 |
ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/12 (20130101) A61L 27/14 (20130101) A61L 27/18 (20130101) A61L 27/18 (20130101) A61L 27/20 (20130101) A61L 27/38 (20130101) A61L 27/54 (20130101) A61L 27/56 (20130101) A61L 27/58 (20130101) A61L 27/3608 (20130101) A61L 27/3695 (20130101) Original (OR) Class A61L 2300/256 (20130101) A61L 2300/258 (20130101) A61L 2300/414 (20130101) A61L 2400/08 (20130101) A61L 2400/12 (20130101) A61L 2430/02 (20130101) Compositions of Macromolecular Compounds C08L 67/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097500 | Xie et al. |
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FUNDED BY |
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APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Pengfei Xie (Piscataway, New Jersey); Mehdi Javanmard (West Windsor, New Jersey); Mark George Allen (Philadelphia, Pennsylvania); Wen Shen (Arlington, Texas); Naixin Song (Philadelphia, Pennsylvania) |
ABSTRACT | A sensor for detecting a target analyte in a sample includes a pair of conducting electrodes that are separated by a gap. An insulator is disposed in the gap between the electrodes. Plural wells are defined by one of the electrodes and the insulator, to expose the other of the electrodes. The wells are configured to receive a sample including a target analyte. The target analyte, when present in the sample received in the wells, modulates an impedance between the electrodes. The modulated impedance, which is measurable with an applied electrical voltage, is indicative of the concentration of the target analyte in the sample. The wells can include antibodies immobilized inside the wells, to bind the target analyte, which can be a cytokine. Also provided are a method for label-free sensing of a target analyte in a sample, and a transcutaneous impedance sensor for label-free, in-situ biomarker detection. |
FILED | Friday, April 17, 2020 |
APPL NO | 16/852113 |
ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5085 (20130101) Original (OR) Class B01L 2300/123 (20130101) B01L 2300/0636 (20130101) B01L 2300/0645 (20130101) B01L 2300/0893 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/02 (20130101) G01N 33/6863 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097567 | Herrington et al. |
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FUNDED BY |
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APPLICANT(S) | Voxel Innovations, Inc. (Raleigh, North Carolina) |
ASSIGNEE(S) | Voxel Innovations, Inc. (Raleigh, North Carolina) |
INVENTOR(S) | Daniel Herrington (Raleigh, North Carolina); Eric Rountree (Raleigh, North Carolina) |
ABSTRACT | A technique of removing material from metal parts referred to as OPECM and a corresponding OPECM processing machine are disclosed. A tool electrode is manufactured for removing material from a target workpiece, and the workpiece and tool electrode are fixed into a processing machine that imparts an oscillatory motion path or profile and applies a voltage through a flowing electrolyte solution. The disclosed technique and processing machine removes material from the surface of the target workpiece through proximal surface dissolution as the workpiece and tool electrode are brought within proximity of one another. |
FILED | Thursday, December 30, 2021 |
APPL NO | 17/565817 |
ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/62 (20210101) Working of Metal by the Action of a High Concentration of Electric Current on a Workpiece Using an Electrode Which Takes the Place of a Tool; Such Working Combined With Other Forms of Working of Metal B23H 3/04 (20130101) Original (OR) Class B23H 7/28 (20130101) B23H 2400/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/20 (20200101) B33Y 80/00 (20141201) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/16 (20130101) C25F 7/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097645 | Repko et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
INVENTOR(S) | Alexander James Repko (Pittsburgh, Pennsylvania); Kacey Gribbin Marra (Canonsburg, Pennsylvania); Benjamin Schilling (Pittsburgh, Pennsylvania) |
ABSTRACT | The presently disclosed subject matter relates to systems for making an implantable construct comprising a reservoir coupled to the at least one frame; a mandrel base coupled to the at least one frame; a mandrel coupled to the mandrel base; a first mechanism configured to be coupled to the at least one frame and configured to move the at least one frame along a first axis; a second mechanism configured to be coupled to the at least one frame and configured to rotate the least one mandrel base along a second axis between a first orientation and a second orientation; and a container configured to be coupled to the at least one frame and configured to receive the mandrel in the second orientation. The disclosed mechanisms can manually, semi-automatically, or automatically control the movements of the at least one frame, reservoir, mandrel, mandrel base, and container to produce the construct with a lumen. The presently disclosed subject matter also relates to methods for making the construct. |
FILED | Tuesday, September 14, 2021 |
APPL NO | 17/474197 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 41/14 (20130101) Original (OR) Class B29C 41/22 (20130101) B29C 41/52 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2995/006 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7532 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097939 | Seeley |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
INVENTOR(S) | Eric Seeley (Seebeck, Washington) |
ABSTRACT | A field configurable vehicle includes bladders located interior of the vehicle hull walls. One or more of the bladders can be filled with fluids of varying densities to manage the buoyancy, mass properties, and thermal heat dissipation of the vehicle. |
FILED | Friday, June 30, 2023 |
APPL NO | 18/217517 |
ART UNIT | 3617 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/04 (20130101) B63G 8/14 (20130101) Original (OR) Class B63G 8/22 (20130101) B63G 2008/004 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098062 | Henderson |
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FUNDED BY |
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APPLICANT(S) | Integrated Solutions for Systems, Inc. (Huntsville, Alabama) |
ASSIGNEE(S) | Integrated Solutions for Systems, Inc. (Huntsville, Alabama) |
INVENTOR(S) | Robert D. Henderson (Huntsville, Alabama) |
ABSTRACT | The present disclosure is an autonomous robotic cargo system for moving and accurately positioning cargo inside an aircraft or at any other designated location in an austere environment. The system has a chassis coupled to one or more tracks for moving the chassis from a first location to a second location. The chassis is also coupled to one or more forks for loading cargo and unloading the cargo. In addition, the chassis has a laser scanner positioned on the chassis to capture data indicative of the chassis' environment. The system further has a control processor that pre-generates a preliminary pathway for the chassis to travel from the first location to the second location based upon laser scanner data received from the laser scanner. The control processor also controls the one or more forks to pick up cargo and controls the one or more tracks to move the cargo from the first location to the second location. |
FILED | Wednesday, July 15, 2020 |
APPL NO | 16/930073 |
ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Hoisting, Lifting, Hauling or Pushing, Not Otherwise Provided For, e.g Devices Which Apply a Lifting or Pushing Force Directly to the Surface of a Load B66F 9/063 (20130101) Original (OR) Class B66F 9/0755 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/024 (20130101) G05D 1/027 (20130101) G05D 1/0236 (20130101) G05D 1/0242 (20130101) Image Data Processing or Generation, in General G06T 7/579 (20170101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098118 | Fairbanks et al. |
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FUNDED BY |
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APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
INVENTOR(S) | Carolyn A. Fairbanks (Minneapolis, Minnesota); Herbert T. Nagasawa (Minneapolis, Minnesota); George L. Wilcox (Minneapolis, Minnesota); Cristina D. Peterson (Minneapolis, Minnesota); Kelley F. Kitto (Minneapolis, Minnesota) |
ABSTRACT | The invention provides a compound of formula I and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the formula I compounds, as well as methods of using such as therapeutic agents for the treatment of pain-related disorders and diseases and in combination with other therapeutic agents. |
FILED | Wednesday, November 06, 2019 |
APPL NO | 17/291345 |
ART UNIT | 1629 — Organic Chemistry |
CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 279/14 (20130101) C07C 279/24 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098172 | Dalton et al. |
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FUNDED BY |
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APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
INVENTOR(S) | William Brian Dalton (Baltimore, Maryland); Ben Ho Park (Perry Hall, Maryland); Eric Christenson (Baltimore, Maryland) |
ABSTRACT | The present disclosure relates to compositions and methods for treating cancers. In particular, the present disclosure provides materials and methods for identifying mis-splicing-associated surface antigens (MASAs) generated by altered spliceosome proteins, as well as materials and methods for targeting cancerous tumors expressing MASAs. |
FILED | Tuesday, July 31, 2018 |
APPL NO | 16/635861 |
ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Peptides C07K 14/435 (20130101) Original (OR) Class C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5023 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098193 | Cukierman et al. |
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FUNDED BY |
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APPLICANT(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Institute For Cancer Research (Philadelphia, Pennsylvania) |
INVENTOR(S) | Edna Cukierman (Philadelphia, Pennsylvania); Ralph Francescone (Philadelphia, Pennsylvania); Janusz Franco-Barraza (Philadelphia, Pennsylvania); Kristopher Raghavan (Philadelphia, Pennsylvania) |
ABSTRACT | The present disclosure provides methods of inducing desmoplastic stroma to express a normal phenotype by detecting increased levels of NetG1 or NGL1 in tumor or in desmoplastic stroma isolated from a human subject, and/or detecting NetG1 in circulating extracellular vesicles, and/or detecting increased pFAK in the stroma, and treating the human subject with a therapeutic regimen; and by detecting NetG1 in a microvesicle isolated from a human subject, and/or treating the human subject with a therapeutic regimen. |
FILED | Tuesday, October 09, 2018 |
APPL NO | 16/754877 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/217 (20130101) Peptides C07K 16/22 (20130101) Original (OR) Class C07K 16/2818 (20130101) C07K 16/2827 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57484 (20130101) G01N 2800/7028 (20130101) G01N 2800/7052 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098272 | Reed et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
INVENTOR(S) | Julian H Reed (Champaign, Illinois); Donald M Cropek (Champaign, Illinois) |
ABSTRACT | In one embodiment, a hydrogel-enzyme construct for performing high temperature enzymatic reaction on paraoxon, and/or for performing enzymatic reaction on paraoxon following exposure to high temperature, includes a hydrogel having multiple layers of poly(methacrylic acid) (PMAA) and a plurality of dPTE2 enzyme molecules. Individual dPTE2 enzyme molecules are embedded between adjacent PMAA layers and are covalently bonded with respective individual PMAA layers. The hydrogel-enzyme construct is capable of performing enzymatic reaction on the paraoxon when the paraoxon is exposed to the hydrogel-enzyme construct under a temperature condition of up to above 99° C. and below 100° C. or when the paraoxon is exposed to the hydrogel-enzyme construct after the hydrogel-enzyme construct has been heated to a temperature condition of up to 550° C., where the enzymatic reaction on the paraoxon by individual dPTE2 molecules embedded within the hydrogel occurs at a residual activity of between 20% and 100%. |
FILED | Monday, August 09, 2021 |
APPL NO | 17/397967 |
ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Compositions of Macromolecular Compounds C08L 33/10 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) Enzymes C12Y 301/08001 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098433 | Jewett et al. |
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FUNDED BY |
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APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Julius B. Lucks (Evanston, Illinois); Adam D. Silverman (Chicago, Illinois); Khalid K. Alam (Evanston, Illinois) |
ABSTRACT | Disclosed are methods, devices, kits, components, and compositions for detecting a target molecule in a test sample using a cell-free protein synthesis (CFPS) reaction. The methods, devices, kits, components, and compositions may be utilized for detecting target molecules which may include small molecules and/or metabolites of small molecules. The components and compositions used in the disclosed methods, devices, and kits may be dried or lyophilized and may be present or immobilized on a paper substrate, for example, as a paper test article. |
FILED | Monday, August 05, 2019 |
APPL NO | 17/265785 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/485 (20130101) C12Q 1/6897 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/184 (20240501) G01N 33/521 (20130101) G01N 33/1826 (20130101) G01N 2430/20 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098475 | Grotjohn et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan); Fraunhofer USA (Plymouth, Michigan) |
ASSIGNEE(S) | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (East Lansing, Michigan); Fraunhofer USA (Plymouth, Michigan) |
INVENTOR(S) | Timothy A. Grotjohn (Okemos, Michigan); Ramon Diaz (East Lansing, Michigan); Aaron Hardy (East Lansing, Michigan) |
ABSTRACT | The disclosure relates to large area single crystal diamond (SCD) surfaces and substrates, and their methods of formation. Typical large area substrates can be at least about 25 mm, 50 mm, or 100 mm in diameter or square edge length, and suitable thicknesses can be about 100 μm to 1000 μm. The large area substrates have a high degree of crystallographic alignment. The large area substrates can be used in a variety of electronics and/or optics applications. Methods of forming the large area substrates generally include lateral and vertical growth of SCD on spaced apart and crystallographically aligned SCD seed substrates, with the individual SCD growth layers eventually merging to form a composite SCD layer of high quality and high crystallographic alignment. A diamond substrate holder can be used to crystallographically align the SCD seed substrates and reduce the effect of thermal stress on the formed SCD layers. |
FILED | Thursday, May 16, 2019 |
APPL NO | 17/055943 |
ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/04 (20130101) C30B 25/08 (20130101) C30B 25/12 (20130101) C30B 25/16 (20130101) C30B 25/20 (20130101) C30B 25/025 (20130101) Original (OR) Class C30B 29/04 (20130101) C30B 29/68 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098916 | Mellick et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | David A. Mellick (Hayden, Idaho); Steven O. Troxel (Hayden, Idaho) |
ABSTRACT | An exemplary inventive freeboard detection system includes a tubular watertight temperature-sensing device and a computer. The temperature-sensing device includes a printed circuit board assembly (PCBA), a potting compound, and a hollow rigid tube. Inside the tube the potting compound encapsulates the PCBA, which includes a printed circuit board (PCB) and multiple temperature sensors closely and equidistantly arrayed along the length of the tube. The temperature-sensing device is vertically secured in a partially submerged state to a vessel with the expectation that some of the vertically arrayed temperature sensors will sense air temperature and others will sense water temperature. On an ongoing basis, the computer receives signals from the temperature sensors and processes the signals to monitor freeboard values, which the computer calculates based on differences in temperature measurements corresponding to pairs of consecutive (and/or nonconsecutive) temperature sensors. A maximum calculated difference in temperature measurements is indicative of the location of the water surface. |
FILED | Sunday, October 17, 2021 |
APPL NO | 17/503324 |
ART UNIT | 2863 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 21/085 (20130101) Original (OR) Class Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 1/026 (20130101) G01K 3/14 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/181 (20130101) H05K 5/0039 (20130101) H05K 5/064 (20130101) H05K 2201/10151 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099045 | Rubenstein et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
INVENTOR(S) | H. Mitchell Rubenstein (Beavercreek, Ohio); Anthony Qualley (Washington Township, Ohio) |
ABSTRACT | A thermal desorption tube for chromatography and mass spectrometry analysis. The thermal desorption tube includes a sorbent and a plurality of focusing agents loaded at known, relative amounts onto the sorbent. Each focusing agent is a compound that chromatographically elutes within a retention time similar to a retention time of a target analyte and has a mass spectrum similar to a mass spectrum of the target analyte. The thermal desorption tube is configured to be further loaded with a sample having the target analyte. |
FILED | Wednesday, November 18, 2020 |
APPL NO | 16/951626 |
ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Separation B01D 53/025 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) G01N 30/08 (20130101) G01N 30/7206 (20130101) G01N 30/8668 (20130101) G01N 33/0006 (20130101) G01N 33/0057 (20130101) Original (OR) Class G01N 2030/025 (20130101) G01N 2030/085 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099059 | Biris et al. |
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FUNDED BY |
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APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
ASSIGNEE(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Little Rock, Arkansas) |
INVENTOR(S) | Alexandru S. Biris (Little Rock, Arkansas); Zeid Nima (Little Rock, Arkansas); Yang Xu (Little Rock, Arkansas) |
ABSTRACT | A method of making at least one nanocomposite for surface enhanced Raman spectroscopy (SERS) detection of a target of interest includes forming at least one gold nanorod; coating a silver layer on an outer surface of the gold nanorod; assembling a Raman reporter molecule layer on the coated silver layer, wherein the Raman reporter molecule layer comprises Raman reporter molecules that are detectable by the SERS; coating a thiolated polyethylene glycol (PEG) layer on the assembled Raman reporter molecule layer; and conjugating the coated thiolated PEG layer with molecules of an antibody to make the at least one nanocomposite. |
FILED | Wednesday, September 30, 2020 |
APPL NO | 17/037830 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/553 (20130101) G01N 33/54346 (20130101) Original (OR) Class G01N 33/54353 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099102 | Solmeyer et al. |
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FUNDED BY |
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APPLICANT(S) | Honeywell International Inc. (Charlotte, North Carolina) |
ASSIGNEE(S) | Honeywell International Inc. (Charlotte, North Carolina) |
INVENTOR(S) | Neal Eldrich Solmeyer (Edina, Minnesota); Matthew Wade Puckett (Phoenix, Arizona); Matthew Robbins (Minneapolis, Minnesota); Eugene Freeman (Eden Prairie, Minnesota); Mary Salit (Plymouth, Minnesota) |
ABSTRACT | Systems and method for the delivery of a pump laser using optical diffraction are described herein. In certain embodiments, a system includes a substrate and a waveguide layer formed on the substrate. The waveguide layer includes a first waveguide of a first material configured to receive a probe laser for propagating within the first waveguide. The waveguide layer additionally includes a second waveguide configured to receive a pump laser for propagating within the second waveguide. Further, the waveguide layer includes one or more diffractors configured to direct a portion of the pump laser out of the second waveguide and through the first waveguide. |
FILED | Wednesday, April 20, 2022 |
APPL NO | 17/725284 |
ART UNIT | 2858 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/4215 (20130101) G02B 6/29328 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099245 | Toda et al. |
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FUNDED BY |
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APPLICANT(S) | Intel Corporation (Santa Clara, California) |
ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
INVENTOR(S) | Asako Toda (Santa Clara, California); Chia-Pin Chiu (Tempe, Arizona); Xiaoqian Li (Chandler, Arizona); Yiqun Bai (Chandler, Arizona) |
ABSTRACT | Embodiments disclosed herein include optical packages. In an embodiment, an optical package comprises a package substrate, where the package substrate comprises a recessed edge. In an embodiment, a compute die is on the package substrate, and an optics die on the package substrate and overhanging the recessed edge of the package substrate. In an embodiment, an integrated heat spreader (IHS) is over the compute die and the optics die. In an embodiment, a lid covers the recess in the package substrate. |
FILED | Thursday, December 17, 2020 |
APPL NO | 17/125481 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4243 (20130101) G02B 6/4253 (20130101) Original (OR) Class G02B 6/4268 (20130101) G02B 6/4269 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099538 | Chew |
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FUNDED BY |
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APPLICANT(S) | Peter A. Chew (Albuquerque, New Mexico) |
ASSIGNEE(S) | Galisteo Consulting Group, Inc. (Albuquerque, New Mexico) |
INVENTOR(S) | Peter A. Chew (Albuquerque, New Mexico) |
ABSTRACT | Disclosed is a flexible, scalable method for automatically distinguishing between the ‘mainstream’ and ‘fringe’ in any text dataset, such as unstructured social media data. The disclosed method allows analysts quickly to pinpoint text articulating fringe beliefs or theories, without prior knowledge of the nature of the fringe beliefs, and can be applied to text data in any language, provided the data can be represented electronically. The method works automatically and without any preconceived notions of what is important or what vocabulary is used in the context of certain beliefs. An analyst's attention is then quickly focused either on new conspiracy theories taking hold (potentially allowing decision-makers to act to interdict the ‘next QAnon insurrection’), or on well-founded beliefs that simply are not yet mainstream. Either way, analysts are empowered better to ‘connect the dots’ for a more complete understanding of the information environment. |
FILED | Friday, October 29, 2021 |
APPL NO | 17/514283 |
ART UNIT | 2656 — Digital Audio Data Processing |
CURRENT CPC | Electric Digital Data Processing G06F 16/35 (20190101) Original (OR) Class G06F 18/231 (20230101) G06F 40/284 (20200101) G06F 2218/00 (20230101) Image or Video Recognition or Understanding G06V 30/416 (20220101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099903 | Inoue et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
INVENTOR(S) | Ken Inoue (Elmsford, New York); Maika Takita (Croton on Hudson, New York); Antonio Corcoles-Gonzalez (Mount Kisco, New York); Scott Douglas Lekuch (New York, New York) |
ABSTRACT | One or more systems, devices, computer program products and/or computer-implemented methods of use provided herein relate to a process to dynamically determine a threshold for determining a state of a qubit and apply the threshold for operating a pulse to de-excite the qubit. A system can comprise a memory that stores computer executable components, and a processor that executes the computer executable components stored in the memory, wherein the computer executable components can comprise a decision component that is configured to determine a threshold of a plurality of thresholds to apply to measurement of a state of a qubit based on a probability distribution of state of the qubit, wherein a measurement at one side of the threshold is representative of the qubit being in the ground state, and wherein a measurement at another side of the threshold is representative of the qubit being in an excited state. |
FILED | Monday, July 18, 2022 |
APPL NO | 17/813082 |
ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) G06N 10/70 (20220101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12100539 | Bennett et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
INVENTOR(S) | Steven P. Bennett (Accokeek, Maryland); Cory D. Cress (Springfield, Virginia); Joseph Prestigiacomo (Huntington, Maryland); Olaf M. J. van 't Erve (Falls Church, Virginia) |
ABSTRACT | Also disclosed herein is an article having a substrate and a layer of an FeRh alloy disposed on the substrate. The alloy has a continuous antiferromagnetic phase and one or more discrete phases smaller in area than the continuous phase having a lower metamagnetic transition temperature than the continuous phase. Also disclosed herein is a method of: providing an article having a substrate and a layer having a continuous phase of an antiferromagnetic FeRh alloy disposed on the substrate and directing an ion source at one or more portions of the alloy to create one or more discrete phases having a lower metamagnetic transition temperature than the continuous phase. |
FILED | Thursday, June 11, 2020 |
APPL NO | 16/898851 |
ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/002 (20130101) Original (OR) Class H01F 10/14 (20130101) H01F 10/28 (20130101) H01F 41/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12100804 | Angell et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
INVENTOR(S) | Charles Austen Angell (Mesa, Arizona); Iolanda Santana Klein (Tempe, Arizona); Telpriore Greg Tucker (Phoenix, Arizona) |
ABSTRACT | A solid electrolyte represented by general formula LiySiRx(MO4), where x is an integer from 1 to 3 inclusive, y=4−x, each R present is independently C1-C3 alkyl or C1-C3 alkoxy, and M is sulfur, selenium, or tellurium. Methods of making the solid electrolyte include combining a phenylsilane and a first acid to yield mixture including benzene and a second acid, and combining at least one of an alkali halide, and alkali amide, and an alkali alkoxide with the second acid to yield a product d represented by general formula LiySiRx(MO4)y. The second acid may be in the form of a liquid or a solid. The phenylsilane includes at least one C1-C3 alkyl substituent or at least one C1-C3 alkoxy substituent, and the first acid includes at least one of sulfuric acid, selenic acid, and telluric acid. |
FILED | Wednesday, June 07, 2023 |
APPL NO | 18/330948 |
ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/025 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/056 (20130101) H01M 10/0525 (20130101) H01M 10/0561 (20130101) H01M 10/0562 (20130101) H01M 10/0564 (20130101) Original (OR) Class H01M 10/0565 (20130101) H01M 10/0567 (20130101) H01M 2300/006 (20130101) H01M 2300/0065 (20130101) H01M 2300/0068 (20130101) H01M 2300/0091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12100848 | Evans et al. |
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FUNDED BY |
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APPLICANT(S) | Aspen Aerogels, Inc. (Northborough, Massachusetts) |
ASSIGNEE(S) | Aspen Aerogels, Inc. (Northborough, Massachusetts) |
INVENTOR(S) | Owen Evans (Chelmsford, Massachusetts); Nicholas Zafiropoulos (Wayland, Massachusetts); Shannon White (Hudson, Massachusetts); Wenting Dong (Marlborough, Massachusetts); Wendell Rhine (Belmont, Massachusetts) |
ABSTRACT | The present invention provides a fiber-reinforced aerogel material which can be used as insulation. The fiber-reinforced aerogel material is highly durable, flexible, and has a thermal performance that exceeds the insulation materials currently used. The fiber-reinforced aerogel insulation material can be as thin as 1 mm or less, and can have a thickness variation as low as 2% or less. Also provided is a method for improving the performance of a battery by incorporating a reinforced aerogel material into the battery. Further provided is a casting method for producing thin fiber-reinforced aerogel materials. |
FILED | Monday, December 04, 2023 |
APPL NO | 18/528371 |
ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0091 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 6/36 (20130101) H01M 6/5072 (20130101) H01M 50/116 (20210101) H01M 50/117 (20210101) H01M 50/121 (20210101) H01M 50/122 (20210101) H01M 50/124 (20210101) H01M 50/131 (20210101) H01M 50/133 (20210101) H01M 50/138 (20210101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12101357 | Soroush et al. |
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FUNDED BY |
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APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
ASSIGNEE(S) | Xerox Corporation (Norwalk, Connecticut) |
INVENTOR(S) | Hamed Soroush (San Jose, California); Milad Asgari Mehrabadi (Irvine, California); Shantanu Rane (Menlo Park, California); Massimiliano Albanese (Potomac, Maryland) |
ABSTRACT | Embodiments provide a system and method for constructing a graph-based model for optimizing the security posture of a composed system. During operation, the system constructs a multi-layer graph for a system with a plurality of components, wherein the multi-layer graph comprises a configuration subgraph, a vulnerability subgraph, and a dependency subgraph. The system constructs the multi-layer graph by the following. The system generates nodes in the configuration subgraph, including: nodes in a first class which encode information associated with a configuration parameter for a respective component, wherein the encoded information includes a name, a default value, a range of values, and a data type; and nodes in a second class which encode value assignments for configuration parameters and relationships between configuration parameters. The system generates nodes in the vulnerability subgraph based on known vulnerabilities associated with a component, bad security practices, and best security practices. |
FILED | Wednesday, July 01, 2020 |
APPL NO | 16/918971 |
ART UNIT | 2496 — Cryptography and Security |
CURRENT CPC | Electric Digital Data Processing G06F 16/252 (20190101) G06F 21/577 (20130101) G06F 2221/034 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 5/04 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/205 (20130101) Original (OR) Class H04L 63/1433 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12101693 | Borel-Donohue |
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FUNDED BY |
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APPLICANT(S) | U.S. Gov't as Represented by Sec of Army c/o U.S Army DEVCOM Army Research Laboratory (Adelphi, Maryland); U.S. Gov, as represented by the Sec of Army c/o U.S. Army DEVCOM Army Research Laboratory (Adelphi, Maryland) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
INVENTOR(S) | Christoph C. Borel-Donohue (Silver Spring, Maryland) |
ABSTRACT | Methods, systems, and computer code on computer-readable media are provided that are directed to generating area skyline data using a digital elevation or surface models (DEMs or DESs) and shadow casting techniques. Some embodiments use an area of maximum shadow line overlap, for shadow line images based on target location skyline azimuth and elevation angle data, as the best approximation for the position of the target location in an area. Some embodiments select the location showing the best fit to the target skyline azimuth and elevation angle data as the best approximation for the target location. |
FILED | Thursday, May 25, 2023 |
APPL NO | 18/202086 |
ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3602 (20130101) Image Data Processing or Generation, in General G06T 7/75 (20170101) G06T 15/60 (20130101) G06T 2207/30244 (20130101) G06T 2215/12 (20130101) Image or Video Recognition or Understanding G06V 20/39 (20220101) Wireless Communication Networks H04W 4/029 (20180201) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12101870 | Kobernik et al. |
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FUNDED BY |
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APPLICANT(S) | SHINE Technologies, LLC (Janesville, Wisconsin) |
ASSIGNEE(S) | SHINE Technologies, LLC (Janesville, Wisconsin) |
INVENTOR(S) | Arne Kobernik (Monona, Wisconsin); Carl Sherven (Monona, Wisconsin); Casey Lamers (Monona, Wisconsin); Chris Seyfert (Monona, Wisconsin); Evan Sengbusch (Monona, Wisconsin); Gabriel Becerra (Monona, Wisconsin); Jin Lee (Monona, Wisconsin); Logan Campbell (Monona, Wisconsin); Mark Thomas (Monona, Wisconsin); Michael Taylor (Monona, Wisconsin); Preston Barrows (Monona, Wisconsin); Ross Radel (Monona, Wisconsin); Tye Gribb (Monona, Wisconsin) |
ABSTRACT | Provided herein are high energy ion beam generator systems and methods that provide low cost, high performance, robust, consistent, uniform, low gas consumption and high current/high-moderate voltage generation of neutrons and protons. Such systems and methods find use for the commercial-scale generation of neutrons and protons for a wide variety of research, medical, security, and industrial processes. |
FILED | Monday, January 09, 2023 |
APPL NO | 18/094724 |
ART UNIT | 2844 — Electrical Circuits and Systems |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/08 (20130101) H01J 37/32082 (20130101) H01J 41/04 (20130101) H01J 41/14 (20130101) Spark Gaps; Overvoltage Arresters Using Spark Gaps; Sparking Plugs; Corona Devices; Generating Ions to be Introduced into Non-enclosed Gases H01T 23/00 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 31/26 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/46 (20130101) H05H 1/54 (20130101) H05H 1/4622 (20210501) H05H 3/06 (20130101) H05H 5/04 (20130101) H05H 6/00 (20130101) H05H 7/22 (20130101) Original (OR) Class H05H 9/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12102005 | Schwede et al. |
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FUNDED BY |
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APPLICANT(S) | Spark Thermionics, Inc. (Berkeley, California) |
ASSIGNEE(S) | Spark Thermionics, Inc. (Berkeley, California) |
INVENTOR(S) | Jared William Schwede (Berkeley, California); Lucas Heinrich Hess (Berkeley, California) |
ABSTRACT | A thermionic energy converter, preferably including an anode and a cathode. An anode of a thermionic energy converter, preferably including an n-type semiconductor, one or more supplemental layers, and an electrical contact. A method for work function reduction and/or thermionic energy conversion, preferably including inputting thermal energy to a thermionic energy converter, illuminating an anode of the thermionic energy converter, thereby preferably reducing a work function of the anode, and extracting electrical power from the system. |
FILED | Wednesday, November 23, 2022 |
APPL NO | 17/993195 |
ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 45/00 (20130101) Electric solid-state devices not otherwise provided for H10N 10/13 (20230201) Original (OR) Class H10N 10/851 (20230201) H10N 10/853 (20230201) H10N 10/855 (20230201) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 12096999 | Frederick et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
INVENTOR(S) | Tom Frederick (Lincoln, Nebraska); Eric Markvicka (Brush, Colorado); Shane Farritor (Lincoln, Nebraska); Dmitry Oleynikov (Omaha, Nebraska) |
ABSTRACT | The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices. |
FILED | Thursday, August 04, 2022 |
APPL NO | 17/880823 |
ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) A61B 18/082 (20130101) A61B 18/1445 (20130101) A61B 34/30 (20160201) Original (OR) Class A61B 2017/00398 (20130101) A61B 2017/00407 (20130101) A61B 2017/00477 (20130101) A61B 2018/00595 (20130101) A61B 2018/1253 (20130101) A61B 2018/1422 (20130101) A61B 2034/305 (20160201) A61B 2217/005 (20130101) A61B 2217/007 (20130101) A61B 2218/002 (20130101) A61B 2218/007 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/046 (20130101) B25J 9/0087 (20130101) B25J 9/102 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097015 | Boamah et al. |
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FUNDED BY |
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APPLICANT(S) | Northwestern University (Evanston, Illinois); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
ASSIGNEE(S) | Northwestern University (Evanston, Illinois); California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Mavis D. Boamah (Evanston, Illinois); Franz M. Geiger (Evanston, Illinois); Thomas F. Miller, III (South Pasadena, California); Jeongmin Kim (Pasadena, California) |
ABSTRACT | Energy harvesting devices and methods for converting the mechanical energy of a flowing ionic solution, such as rainwater or seawater, into electric energy are provided. The energy harvesting devices include an electric current generating device that includes a metal layer and an amphoteric metal oxide film disposed over a surface of the metal layer. By moving an electric double layer across the surface of the amphoteric metal oxide film, an electric current is generated in the metal layer. |
FILED | Tuesday, September 17, 2019 |
APPL NO | 17/276684 |
ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/026 (20130101) Original (OR) Class Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) H02N 11/002 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097159 | Walsh et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Conor J. Walsh (Cambridge, Massachusetts); Ciaran O'Neill (Cambridge, Massachusetts); Nathan Phipps (Somerville, Massachusetts) |
ABSTRACT | A textile actuator worn by a user comprises a textile envelope that defines a chamber made fluid-impermeable by a fluid-impermeable bladder contained in the textile envelope and/or a fluid-impermeable structure incorporated into the textile envelope. The textile envelope has a pre-determined geometry that produces an equilibrium state at a non-180-angle displacement and that stops further displacement upon pressurization of the chamber and prevents over-extension the joint. A fluid is delivered into or out of the chamber to displace the textile envelope primarily by transitioning from an uninflated state to the pre-determined geometry due to displacement of the textile envelope rather than via stretching or contraction of the textile envelope. When actuated, the textile actuator (a) displaces a body segment of the user and/or (b) supports and holds the body segment of the user in place. |
FILED | Thursday, May 31, 2018 |
APPL NO | 16/614862 |
ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/04 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0274 (20130101) Original (OR) Class A61H 2201/0103 (20130101) A61H 2201/165 (20130101) A61H 2201/1238 (20130101) A61H 2201/1635 (20130101) A61H 2201/1659 (20130101) A61H 2201/5058 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) B25J 9/1694 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/103 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097239 | Rivera-Feliciano et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Jose Rivera-Feliciano (Brookline, Massachusetts); Edwin Rosado-Olivieri (Somerville, Massachusetts); Douglas A. Melton (Lexington, Massachusetts) |
ABSTRACT | A previously uncharacterized gene and gene product are disclosed herein that increase blood glucose clearance independent of insulin. Also described is a methodology for enriching for mRNAs transcribing excreted and membrane bound proteins as well as a non-human animal expressing a labeled SEC61b protein. |
FILED | Monday, September 23, 2019 |
APPL NO | 17/278644 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097290 | Zhang et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Liangfang Zhang (San Diego, California); Che-Ming (Jack) Hu (San Diego, California); Ronnie Hongbo Fang (Irvine, California); Jonathan Copp (La Jolla, California) |
ABSTRACT | Provided are nanoparticles and methods of using and making thereof. The inventive nanoparticle comprises a) an inner core comprising a non-cellular material; and b) an outer surface comprising a cellular membrane derived from a cell or a membrane derived from a virus. Medicament delivery systems or pharmaceutical compositions comprising the inventive nanoparticles are also provided. Further provided are immunogenic compositions comprising the inventive nanoparticles, and methods of using the inventive immunogenic compositions for eliciting an immune response, and for treating or preventing diseases or condition, such as neoplasm or cancer, or disease or conditions associated with cell membrane inserting toxin. Vaccines comprising the immunogenic composition comprising the nanoparticles are also provided. |
FILED | Thursday, March 14, 2013 |
APPL NO | 13/827906 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/148 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 39/085 (20130101) A61K 39/001102 (20180801) A61K 45/06 (20130101) A61K 2039/80 (20180801) A61K 2039/55555 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097475 | Ismagilov et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Rustem F. Ismagilov (Chicago, Illinois); Bo Zheng (Chicago, Illinois); Cory John Gerdts (Chicago, Illinois) |
ABSTRACT | The present invention provides microfluidic technology enabling rapid and economical manipulation of reactions on the femtoliter to microliter scale. |
FILED | Friday, January 12, 2024 |
APPL NO | 18/412395 |
ART UNIT | 1796 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 25/314 (20220101) B01F 33/3021 (20220101) Original (OR) Class Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/0059 (20130101) B01J 2219/00522 (20130101) B01J 2219/00585 (20130101) B01J 2219/00599 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/06 (20130101) B01L 3/0293 (20130101) B01L 3/527 (20130101) B01L 3/502723 (20130101) B01L 3/502746 (20130101) B01L 3/502784 (20130101) B01L 2200/0673 (20130101) B01L 2300/0816 (20130101) B01L 2300/0838 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2400/0406 (20130101) B01L 2400/0409 (20130101) B01L 2400/0415 (20130101) B01L 2400/0433 (20130101) B01L 2400/0487 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/00 (20130101) C30B 29/58 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/38 (20130101) G01N 35/08 (20130101) G01N 2035/1034 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 7/0694 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) Y10T 436/12 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097620 | Tan et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
ASSIGNEE(S) | University of Tennesse Research Foundation (Knoxville, Tennessee) |
INVENTOR(S) | Jindong Tan (Knoxville, Tennessee); Da Hu (Louisville, Tennessee); Qiang He (Knoxville, Tennessee); Shuai Li (Knoxville, Tennessee) |
ABSTRACT | Provided are methods and apparatus for environment-adaptive robotic disinfecting. In an example, provided is a method that can include (i) creating, from digital images, a map of a structure; (ii) identifying a location of a robot in the structure; (iii) segmenting, using a machine learning-based classifying algorithm trained based on object affordance information, the digital images to identify potentially contaminated surfaces within the structure; (iv) creating a map of potentially contaminated surfaces within the structure; (v) calculating a trajectory of movement of the robot to move the robot to a location of a potentially contaminated surface in the potentially contaminated surfaces; and (vi) moving the robot along the trajectory of movement to position a directional decontaminant source adjacent to the potentially contaminated surface. Other methods, systems, and computer-readable media are also disclosed. |
FILED | Wednesday, August 25, 2021 |
APPL NO | 17/445898 |
ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/24 (20130101) A61L 2202/14 (20130101) A61L 2202/16 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 5/007 (20130101) B25J 9/161 (20130101) B25J 9/1664 (20130101) Original (OR) Class B25J 9/1669 (20130101) B25J 15/0019 (20130101) Electric Digital Data Processing G06F 18/2148 (20230101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 20/20 (20220101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097878 | Gaffin-Cahn |
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FUNDED BY |
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APPLICANT(S) | Perceptive Automata, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Perceptive Automata, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Elon Gaffin-Cahn (Boston, Massachusetts) |
ABSTRACT | A system receives information describing paths traversed by vehicles of a vehicle type, for example, a bicycle or a motorcycle. The system determines locations along the paths. For each location the system determines a measure of likelihood of encountering vehicles of the vehicle type in traffic at the location. The system selects a subset of locations based on the measure of likelihood and obtains sensor data captured at the subset of locations. The system uses the sensor data as training dataset for training a machine learning based model configured to receive input sensor data describing traffic and output a score used for navigation of autonomous vehicles. The machine learning model is provided to a vehicle, for example, an autonomous vehicle for navigation of the autonomous vehicle. |
FILED | Tuesday, April 26, 2022 |
APPL NO | 17/730048 |
ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 40/04 (20130101) B60W 60/0011 (20200201) Original (OR) Class B60W 2554/402 (20200201) B60W 2554/4041 (20200201) B60W 2556/10 (20200201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098026 | Li et al. |
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FUNDED BY |
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APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
INVENTOR(S) | Guohong Li (Highland Park, New Jersey); Eva Y. Andrei (Highland Park, New Jersey); Angela Coe (Tenstrike, Minnesota) |
ABSTRACT | A system for transferring objects into a device inside a controlled environment includes a winch, tool and carousel. The winch includes a drum, and wire arrangement configured to be reversibly wound onto the drum by a first drive. The tool is suspended below a distal end of the wire arrangement and configured to suspend an object. Both the tool and the object are sized to fit inside a device located below the winch. The carousel is connected to a second drive configured to rotate the carousel around a vertical axis, and includes a storage space centered at a first horizontal angle and a pass-through opening at a different second horizontal angle. The pass-through opening being large enough to pass the tool and the object as the wire arrangement is unwound from the drum thereby lowering the tool and object inside the device. |
FILED | Wednesday, April 17, 2019 |
APPL NO | 15/733768 |
ART UNIT | 3654 — Material and Article Handling |
CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 1/045 (20130101) B65G 1/0464 (20130101) Original (OR) Class Cranes; Load-engaging Elements or Devices for Cranes, Capstans, Winches, or Tackles B66C 1/24 (20130101) Capstans; Winches; Tackles, e.g Pulley Blocks; Hoists B66D 1/26 (20130101) Frames, Casings or Beds of Engines, Machines or Apparatus, Not Specific to Engines, Machines or Apparatus Provided for Elsewhere; Stands; Supports F16M 13/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098456 | Rajagopalan et al. |
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FUNDED BY |
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APPLICANT(S) | Jagannathan Rajagopalan (Tempe, Arizona); Paul Rasmussen (Tempe, Arizona) |
ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
INVENTOR(S) | Jagannathan Rajagopalan (Tempe, Arizona); Paul Rasmussen (Tempe, Arizona) |
ABSTRACT | Methods for controlled microstructure creation utilize seeding of amorphous layers prior to annealing. Seed crystals are formed on an amorphous layer or layers. The material, size, and spacing of the seed crystals may be varied, and multiple seed layers and/or amorphous layers may be utilized. Thereafter, the resulting assembly is annealed to generate a crystalline microstructure. Via use of these methods, devices having desirable microstructural properties are enabled. |
FILED | Wednesday, August 18, 2021 |
APPL NO | 17/405194 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/024 (20130101) Original (OR) Class C23C 14/5806 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12098471 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
ASSIGNEE(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
INVENTOR(S) | Dunwei Wang (Newton, Massachusetts); Qi Dong (Newton, Massachusetts); Xizi Zhang (Berkeley, California) |
ABSTRACT | A flow cell for reducing carbon dioxide may include a first chamber having a gold coated gas diffusion layer working electrode, a reference electrode, and a water-in-salt electrolyte comprising a super concentrated aqueous solution of lithium bis-(trifluoromethanesulfonyl)imide (LiTFSI). A second chamber adjacent the first chamber has a gold coated gas diffusion layer counter electrode and the water-in-salt electrolyte. The second chamber being separated from the first chamber by a proton exchange membrane. A reservoir coupled to each of the first and the second chambers with a pump contains a volume of the water-in-salt electrolyte and a head space. |
FILED | Tuesday, February 28, 2023 |
APPL NO | 18/175782 |
ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 1/23 (20210101) C25B 9/15 (20210101) Original (OR) Class C25B 9/19 (20210101) C25B 11/032 (20210101) C25B 11/077 (20210101) C25B 11/081 (20210101) C25B 15/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099012 | Ly et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Victoria Ly (Santa Cruz, California); Pierre Baudin (Santa Cruz, California); Pattawong Pansodtee (Santa Cruz, California); Erik Jung (Santa Cruz, California); Robert Currie (Santa Cruz, California); David Haussler (Santa Cruz, California); Mircea Teodorescu (Santa Cruz, California) |
ABSTRACT | An imaging system includes an imaging device having a holder configured to hold a cell culture plate with a plurality of wells. The imaging device also includes an imaging assembly having a plurality of imaging units, each of which is configured to image one well of the plurality of wells. The imaging system also includes a storage platform in communication with the imaging device configured to receive a plurality of images from the imaging device. The system further includes a computer in communication with the imaging device and the storage platform. The computer is configured to control the imaging device and to display at least one image of the plurality of images. |
FILED | Friday, May 06, 2022 |
APPL NO | 17/738251 |
ART UNIT | 2485 — Recording and Compression |
CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 25/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Original (OR) Class G01N 21/6486 (20130101) G01N 2201/021 (20130101) G01N 2201/062 (20130101) Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) Image Data Processing or Generation, in General G06T 7/571 (20170101) G06T 2207/10056 (20130101) G06T 2207/10148 (20130101) G06T 2207/30024 (20130101) G06T 2207/30072 (20130101) Pictorial Communication, e.g Television H04N 5/265 (20130101) H04N 23/62 (20230101) H04N 23/66 (20230101) H04N 23/90 (20230101) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 12096728 | Dreschel et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as Represented by the Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | Thomas W. Dreschel (Titusville, Florida); Jacob J. Torres (Cocoa, Florida) |
ABSTRACT | The invention described herein comprises a passive plant nutrient delivery system that utilizes a hydrophilic porous tube to transfer a liquid nutrient solution from at least one reservoir to the roots of plants. The plants' roots rest on the exterior surface of the tube, where a combination of capillary force, evapotranspiration from the plant, and some evaporation from the surface of the tube draws the nutrient solution passively from the reservoir, or reservoirs, through the tube. The roots uptake water from the tube as needed, requiring no external power source. A flexible cover envelops plants' roots and the tube, whereby the cover has an opening to allow room for plants to grow. The flexible cover is held in place by a securing means, such as a clamp. Both the cover and the securing means are comprised of a material that can expand, allowing the plants adequate room to grow. |
FILED | Wednesday, September 16, 2020 |
APPL NO | 17/023336 |
ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 27/06 (20130101) A01G 27/008 (20130101) A01G 31/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12096999 | Frederick et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
INVENTOR(S) | Tom Frederick (Lincoln, Nebraska); Eric Markvicka (Brush, Colorado); Shane Farritor (Lincoln, Nebraska); Dmitry Oleynikov (Omaha, Nebraska) |
ABSTRACT | The embodiments disclosed herein relate to various robotic and/or in vivo medical devices having compact joint configurations. Other embodiments relate to various medical device components, including forearms having grasper or cautery end effectors, that can be incorporated into certain robotic and/or in vivo medical devices. |
FILED | Thursday, August 04, 2022 |
APPL NO | 17/880823 |
ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) A61B 18/082 (20130101) A61B 18/1445 (20130101) A61B 34/30 (20160201) Original (OR) Class A61B 2017/00398 (20130101) A61B 2017/00407 (20130101) A61B 2017/00477 (20130101) A61B 2018/00595 (20130101) A61B 2018/1253 (20130101) A61B 2018/1422 (20130101) A61B 2034/305 (20160201) A61B 2217/005 (20130101) A61B 2217/007 (20130101) A61B 2218/002 (20130101) A61B 2218/007 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/046 (20130101) B25J 9/0087 (20130101) B25J 9/102 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099006 | Bulcha |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | Berhanu Bulcha (Greenbelt, Maryland) |
ABSTRACT | A heterodyne-based submillimeter-wave spectrometer includes a frequency mixer that combine a local oscillator (LO) signal and a radio frequency (RF) signal to translate from a high frequency to a lower frequency or an intermediate frequency (IF) signal. |
FILED | Wednesday, August 24, 2022 |
APPL NO | 17/894534 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3581 (20130101) Original (OR) Class Demodulation or Transference of Modulation From One Carrier to Another H03D 7/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099219 | Murphey et al. |
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FUNDED BY |
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APPLICANT(S) | Thomas W. Murphey (Fort Collins, Colorado); Patrick A. Rodriguez (Fort Collins, Colorado) |
ASSIGNEE(S) | Opterus Research and Development, Inc. (Fort Collins, Colorado) |
INVENTOR(S) | Thomas W. Murphey (Fort Collins, Colorado); Patrick A. Rodriguez (Fort Collins, Colorado) |
ABSTRACT | A doubly curved reflector for compact storage in a folded state includes a plurality of gores, each gore having on either long side a gore side curve. At least one hinge is mechanically coupled between each adjacent gore, the at least one hinge including a fold roll hinge or a living hinge. In a stowed doubly curved reflector state each gore folds about the at least one hinge when folded closed such that a face surface of each gore folds against an adjacent face surface of another gore into a substantially cylindrical structure. In a deployed doubly curved reflector state, each hinge. A doubly curved reflector for compact storage in a folded state and a locked open state, a method of manufacture, and a method for designing a substantially wrinkle free doubly curved foldable reflector having gores of a composite material are also described. |
FILED | Friday, August 04, 2023 |
APPL NO | 18/230411 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/443 (20130101) Optical Elements, Systems, or Apparatus G02B 5/10 (20130101) Original (OR) Class G02B 27/0012 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12099880 | Liaghati |
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FUNDED BY |
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APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
INVENTOR(S) | Amir Leon Liaghati (Huntsville, Alabama) |
ABSTRACT | A system selects a telemetry allocation for the transmission of data from multiple transmitters. An allocation matrix defines a split ratio for data generated by a data source that is split between transmitters. The split ratio is defined for each data source of a plurality of data sources. (A) A storage buffer model is executed based on the allocation matrix to simulate a buffer that stores data from each data source that exceeds a download bandwidth value. (B) Performance parameter values are stored in association with the allocation matrix. (C) The allocation matrix is updated to redefine at least one split ratio. (D) (A) through (C) is repeated with the allocation matrix replaced with the updated allocation matrix until each unique permutation of values for the split ratio is processed. An allocation matrix is selected from allocation matrices stored in (B) based on the plurality of performance parameter values. |
FILED | Tuesday, October 05, 2021 |
APPL NO | 17/493996 |
ART UNIT | 2194 — Interprocess Communication and Software Development |
CURRENT CPC | Electric Digital Data Processing G06F 9/5022 (20130101) G06F 9/5044 (20130101) Original (OR) Class G06F 11/323 (20130101) G06F 11/3089 (20130101) G06F 11/3466 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 12101394 | Vemury |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Arun Vemury (North Bethesda, Maryland) |
ABSTRACT | Systems and methods for secure distribution of biometric matching processing are provided. Certain configurations include homomorphic encrypting of captured biometric information. In some configurations, the biometric information is classified without decryption between a first identity class and a second identity class. The biometric information may be formed as a feature vector. A homomorphic encrypted feature vector may be formed by homomorphic encrypting of the biometric information. |
FILED | Friday, December 01, 2023 |
APPL NO | 18/526977 |
ART UNIT | 2436 — Cryptography and Security |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) Original (OR) Class H04L 9/3231 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US D1043717 | Boyd et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Daniel A. Boyd (Arlington, Virginia); Kelli L. Biegger (Alexandria, Virginia) |
ABSTRACT | |
FILED | Thursday, October 27, 2022 |
APPL NO | 29/858020 |
ART UNIT | 2923 — Design |
CURRENT CPC | Recording, communication, or information retrieval equipment D14/485 |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 12096863 | Cooper et al. |
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FUNDED BY |
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APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | University of Pittsburg Of the Commonweath System of Higher Education (Pittsburgh, Pennsylvania); The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Rory Alan Cooper (Gibsonia, Pennsylvania); Michael A. Shulock (Murrysville, Pennsylvania); Joshua D. Brown (Pittsburgh, Pennsylvania); Garrett G. Grindle (Pittsburgh, Pennsylvania); Benjamin Todd Gebrosky (Gibsonia, Pennsylvania); Sayeedur Rahman (Issaquah, Washington); Sivan Almosnino (Snoqualmie, Washington); Lisa Garamella (Charlotte, North Carolina); Daniel Robin (Seattle, Washington) |
ABSTRACT | An access system includes a laterally extending frame, a carriage in operative connection with the laterally extending frame and including a drive to move the carriage laterally on the frame, a seat support attached to the carriage including a seat assembly interface and a lift to raise and lower the seat assembly interface within a range of positions, a seat assembly attached to the seat assembly interface, a controller in operative connection with the drive of the carriage and the lift of the seat support via which the position of the seat support is controllable, and a controller interface in operative connection with the controller. |
FILED | Tuesday, August 31, 2021 |
APPL NO | 17/462462 |
ART UNIT | 3632 — Static Structures, Supports and Furniture |
CURRENT CPC | Chairs; Sofas; Beds A47C 1/025 (20130101) A47C 1/0242 (20130101) A47C 3/20 (20130101) A47C 7/62 (20130101) Original (OR) Class A47C 7/5064 (20180801) Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/04 (20130101) A61G 5/128 (20161101) A61G 5/1059 (20130101) A61G 5/1067 (20130101) A61G 2200/34 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097367 | Sabiev et al. |
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FUNDED BY |
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APPLICANT(S) | United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
ASSIGNEE(S) | United States Government As Represented By The Department Of Veterans Affairs (Washington, District of Columbia) |
INVENTOR(S) | Anton Sabiev (Forest Hills, New York); William Bauman (New Rochelle, New York); Mark Korsten (Hastings-on-Hudson, New York) |
ABSTRACT | An iontophoresis system for positioning against skin of a subject is disclosed. The iontophoresis system can comprise at least one vessel having a solvent therein. An anode apparatus can couple to the at least one vessel. The anode apparatus can comprise a first reservoir configured to receive the solvent from the at least one vessel so that, when received into the first reservoir, the solvent makes contact with the skin of the subject, and a first electrode positioned above the first reservoir. A cathode apparatus can couple to the at least one vessel. The cathode apparatus can comprise a second reservoir configured to receive the solvent from the at least one vessel so that, when received into the first reservoir, the solvent makes contact with the skin of the subject, and a second electrode positioned above the second reservoir. |
FILED | Wednesday, May 04, 2022 |
APPL NO | 17/736602 |
ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/30 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 12097268 | Horsager et al. |
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FUNDED BY |
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APPLICANT(S) | EOS Neuroscience, Inc. (San Francisco, California) |
ASSIGNEE(S) | EOS Neuroscience, Inc. (San Francisco, California) |
INVENTOR(S) | Alan Horsager (Los Angeles, California); Andrew Smith (Santa Monica, California); Benjamin C. Matteo (San Francisco, California) |
ABSTRACT | Provided herein are compositions and methods for the design of synthetic regulatory sequences and for subsequent modulation of neural pathways. |
FILED | Thursday, March 19, 2020 |
APPL NO | 16/823905 |
ART UNIT | 1638 — Central Reexamination Unit (Chemical) |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) Original (OR) Class Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14043 (20130101) C12N 2830/007 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12097567 | Herrington et al. |
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FUNDED BY |
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APPLICANT(S) | Voxel Innovations, Inc. (Raleigh, North Carolina) |
ASSIGNEE(S) | Voxel Innovations, Inc. (Raleigh, North Carolina) |
INVENTOR(S) | Daniel Herrington (Raleigh, North Carolina); Eric Rountree (Raleigh, North Carolina) |
ABSTRACT | A technique of removing material from metal parts referred to as OPECM and a corresponding OPECM processing machine are disclosed. A tool electrode is manufactured for removing material from a target workpiece, and the workpiece and tool electrode are fixed into a processing machine that imparts an oscillatory motion path or profile and applies a voltage through a flowing electrolyte solution. The disclosed technique and processing machine removes material from the surface of the target workpiece through proximal surface dissolution as the workpiece and tool electrode are brought within proximity of one another. |
FILED | Thursday, December 30, 2021 |
APPL NO | 17/565817 |
ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/62 (20210101) Working of Metal by the Action of a High Concentration of Electric Current on a Workpiece Using an Electrode Which Takes the Place of a Tool; Such Working Combined With Other Forms of Working of Metal B23H 3/04 (20130101) Original (OR) Class B23H 7/28 (20130101) B23H 2400/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/20 (20200101) B33Y 80/00 (20141201) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/16 (20130101) C25F 7/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US PP36135 | McMahon et al. |
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FUNDED BY |
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APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
INVENTOR(S) | Bernard G. McMahon (Coon Rapids, Minnesota); William Berguson (Duluth, Minnesota) |
ABSTRACT | The invention is a new and distinct variety of male Populus tree named ‘NextGen’ that is characterized by its superior to above average field growth performance, its excellent to above average rooting rate, its disease resistance to foliar rusts (Melampsora sp.), leaf spots (Marssonina sp.) and stem cankers (Septoria sp.), its vigorous vegetative growth and production in nursery stoolbeds, its cold hardiness for overwintering and surviving in Minnesota with no frost damage, its wide-spread superior growth performance in many test locations (ie: MN, MI, WI, IA, IN, NY, etc); able to be considered “geo-robust” after years of testing, its replicated growth testing and evidence of promising performance and evaluation in phytoremediation research testing and applications, and its male flowers that do not produce seeds. |
FILED | Wednesday, November 22, 2023 |
APPL NO | 18/517841 |
ART UNIT | 1661 — Plants |
CURRENT CPC | Plants PLT/218 |
VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
US 12097546 | Scheckel et al. |
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FUNDED BY |
|
APPLICANT(S) | United States Government, as represented by the Administrator of the U.S. EPA (Washington, District of Columbia) |
ASSIGNEE(S) | UNITED STATES GOVERNMENT, AS REPRESENTED BY THE ADMINISTRATOR OF THE U.S. EPA (Washington, District of Columbia) |
INVENTOR(S) | Kirk Gerald Scheckel (Cincinnati, Ohio); Ranju R. Karna (Clinton, Mississippi); Charles R. Partridge (Commerce City, Colorado); Karen D. Bradham (Apex, North Carolina); David James Thomas (Chapel Hill, North Carolina); Matthew R. Noerpel (Cincinnati, Ohio); Jennifer Lynn Goetz (Petersburg, Kentucky); Todd Peter Luxton (Cincinnati, Ohio); Tyler Dale Sowers (Apex, North Carolina) |
ABSTRACT | Methods and systems are provided for treating a contaminated environmental medium. In one example, the treatment includes adding a first jarosite-group mineral to the contaminated environmental medium to form a wet mixture under a set of conditions. The set of conditions is maintained over a duration of time to expedite precipitation of a second jarosite-group mineral, the second jarosite-group mineral incorporating contaminant cations and contaminant anions into a structure of the second jarosite-group mineral. The first jarosite-group mineral is added in situ at a contamination site. |
FILED | Thursday, July 21, 2022 |
APPL NO | 17/814172 |
ART UNIT | 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Reclamation of Contaminated Soil B09C 1/08 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 12099961 | Lawson et al. |
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FUNDED BY |
|
APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Angela Dawn Lawson (Cambridge, Massachusetts); Fatema Momenni Kennedy (Dumfries, Virginia); Junghyun Hwang (Herndon, Virginia) |
ABSTRACT | A system and method for tracking and managing package delivery within a distribution network. Many events happen during the processing, moving, and delivery of a package. Systems and methods herein identify whether all expected events occur, whether scan locations are correct, whether delivery times are met, and other requirements. Problems or potential problems can be identified and corrected. |
FILED | Monday, January 11, 2021 |
APPL NO | 17/145719 |
ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0633 (20130101) G06Q 10/0833 (20130101) Original (OR) Class G06Q 10/06393 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
US 12101346 | Blumenfeld et al. |
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FUNDED BY |
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APPLICANT(S) | Two Six Labs, LLC (Arlington, Virginia) |
ASSIGNEE(S) | Two Six Labs, LLC (Arlington, Virginia) |
INVENTOR(S) | Ian T. Blumenfeld (Arlington, Virginia); David Renardy (Arlington, Virginia) |
ABSTRACT | A method for assessing a regular expression for vulnerability to ReDoS attacks includes receiving a regular expression for evaluating a string defined by ordered set of characters from an alphanumeric input device, and evaluating the regular expression for determining if a parsing operation of the string according to the regular expression results in a disproportionate resource consumption. The evaluation determines if the resource consumption constitutes a Regular expression Denial of Service (ReDOS) attack by providing a vulnerability indication of a single valid attack string, rather than attempting to find all possible attack strings. The valid attack string is defined by an input string for which evaluation based on the regular expression would result in disproportionate resource consumption. |
FILED | Wednesday, July 26, 2023 |
APPL NO | 18/226509 |
ART UNIT | 2435 — Cryptography and Security |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) H04L 63/1433 (20130101) Original (OR) Class H04L 63/1458 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 24, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20240924.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page