FedInvent™ Patents

Patent Details for Tuesday, October 22, 2024 

This page was updated on Tuesday, November 12, 2024 at 04:32 AM GMT

Department of Health and Human Services (HHS) 

US 12121215 Dupont
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Children's Medical Center Corporation (Boston, Massachusetts)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Pierre Dupont (Wellesley, Massachusetts)
ABSTRACT A device for performing surgical procedures, such as intracardiac procedures or neurosurgical procedures, includes a solid optical window formed of a transparent, compliant material, wherein the solid optical window includes a proximal side and a distal side, wherein a distal face of the solid optical window is configured to approach tissue during a surgical procedure; an imaging system embedded into the solid optical window and positioned to obtain an image through at least a portion of the distal face of the solid optical window; and a tool channel formed through the solid optical window from the proximal side to the distal side of the solid optical window, wherein the tool channel is configured to receive a tool for performing the surgical procedure.
FILED Thursday, September 29, 2022
APPL NO 17/956162
ART UNIT 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/05 (20130101)
A61B 1/015 (20130101)
A61B 1/018 (20130101) Original (OR) Class
A61B 1/00082 (20130101)
A61B 1/00087 (20130101)
A61B 1/00089 (20130101)
A61B 1/00096 (20130101)
A61B 1/00179 (20130101)
A61B 10/02 (20130101)
A61B 10/04 (20130101)
A61B 10/0283 (20130101)
A61B 17/00234 (20130101)
A61B 2017/00243 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121339 Gharagouzloo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Codi Gharagouzloo (Medford, Massachusetts);  Srinivas Sridhar (Newton, Massachusetts)
ABSTRACT A quantitative, ultrashort time to echo, contrast-enhanced magnetic resonance imaging technique is provided. The technique can be used to accurately measure contrast agent concentration in the blood, to provide clear, high-definition angiograms, and to measure absolute quantities of cerebral blood volume on a voxel-by-voxel basis.
FILED Thursday, June 09, 2016
APPL NO 15/747202
ART UNIT 3798 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101) Original (OR) Class
A61B 5/425 (20130101)
A61B 5/4064 (20130101)
A61B 5/4088 (20130101)
A61B 5/4244 (20130101)
A61B 5/4866 (20130101)
A61B 2576/026 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4816 (20130101)
G01R 33/5601 (20130101)
G01R 33/5635 (20130101)
G01R 33/56366 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121360 Huggins et al.
FUNDED BY
Department of Education (ED)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Jane E. Huggins (Fenton, Michigan);  Seth Warschausky (Ann Arbor, Michigan);  Ramses Eduardo Alcaide (Ann Arbor, Michigan)
ABSTRACT Methods, systems, apparatus, and non-transitory computer readable media are disclosed utilizing brain-computer interfaces (BCIs). Various embodiments are disclosed to allow a user to directly select multiple-choice answers, to provide motorized wheelchair controls, and to allow a user to play a game via the BCI. When used in a cognitive assessment test, embodiments include the administration of unmodified standardized tests with results in the same or a similar format as those taken without a BCI. Various embodiments are disclosed to improve the accuracy of BCI test administration using a three-step process for each test question, which includes determining whether the user intends to select an answer, monitoring user brain activity to determine a selected answer, and verifying the selected answer. In addition, the selected answer may be verified by monitoring user brain activity in accordance with a hold-release process to determine whether a user intends to initiate a state change.
FILED Tuesday, July 06, 2021
APPL NO 17/368207
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/372 (20210101)
A61B 5/374 (20210101)
A61B 5/378 (20210101)
A61B 5/742 (20130101)
A61B 5/4088 (20130101) Original (OR) Class
A61B 5/7221 (20130101)
A61B 5/7264 (20130101)
A61B 5/7267 (20130101)
A61B 5/7282 (20130101)
A61B 5/7435 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/72 (20130101)
A61F 4/00 (20130101)

Electric Digital Data Processing
G06F 3/015 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 7/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121378 Sheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  Radiabeam Technologies, LLC (Santa Monica, California)
INVENTOR(S) Ke Sheng (Los Angeles, California);  Salime M. Boucher (Santa Monica, California)
ABSTRACT A system for coordinating radiation therapy and imaging processes includes a radiation therapy system an radiation source mounted on a robotically-controlled system to move the radiation source about a subject to direct radiation to a target area in the subject according to a treatment plan. The system also includes an imaging system configured to acquire imaging data from a subject. The imaging system and the radiation therapy system are independently movable. The system also includes a coordination system configured to coordinate operation of the imaging system to acquire the imaging data from the subject during movement of the radiation source about the subject according to the treatment plan to avoid collisions of the radiation therapy system with the imaging system.
FILED Friday, February 23, 2018
APPL NO 16/487946
ART UNIT 3798 — Selective Communication
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/035 (20130101)
A61B 6/102 (20130101) Original (OR) Class
A61B 6/4085 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/1038 (20130101)
A61N 5/1045 (20130101)
A61N 5/1083 (20130101)
A61N 2005/1061 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121404 Wilson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S) The Board of Trustees of The Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of The Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Fletcher T. Wilson (San Francisco, California);  Rhunjay James Yu (Mountain View, California)
ABSTRACT A device for manipulating tissue at a vessel includes an elongated member having a proximal end and a distal end, a guide member at the distal end of the elongated member, the guide member having a blunt distal tip for engagement against an interior wall of the vessel, and a tissue cutting device at the distal end of the elongated member, wherein the tissue cutting device has a sharp tip that is proximal to the blunt distal tip of the guide member.
FILED Monday, December 14, 2020
APPL NO 17/121714
ART UNIT 3771 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 17/0644 (20130101)
A61B 17/3203 (20130101)
A61B 17/3209 (20130101)
A61B 17/22031 (20130101)
A61B 17/320016 (20130101)
A61B 17/320783 (20130101)
A61B 90/02 (20160201) Original (OR) Class
A61B 2017/306 (20130101)
A61B 2017/00783 (20130101)
A61B 2017/00867 (20130101)
A61B 2017/22052 (20130101)
A61B 2017/22069 (20130101)
A61B 2017/22071 (20130101)
A61B 2017/22077 (20130101)
A61B 2017/22095 (20130101)
A61B 2017/32006 (20130101)
A61B 2017/320044 (20130101)
A61B 2017/320048 (20130101)
A61B 2017/320056 (20130101)
A61B 2017/320064 (20130101)
A61B 2017/320741 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 25/0147 (20130101)
A61M 25/1002 (20130101)
A61M 2025/1047 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121500 Tavis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Saint Louis University (St. Louis, Missouri);  Research Foundation of The City University of New York (New York, New York)
ASSIGNEE(S) Saint Louis University (St. Louis, Missouri);  Research Foundation of the City University of New York (New York, New York)
INVENTOR(S) John Edwin Tavis (Kirkwood, Missouri);  Amelia Pinto (St. Louis, Missouri);  James Brien (St. Louis, Missouri);  Ryan Murelli (Belleville, New Jersey)
ABSTRACT The present disclosure provides inhibitors of bunyavirus of the formula:
wherein the variables are defined herein. These inhibitors may be used to treat an infection of Rift Valley phlebovirus, hantavirus, and La Crosse virus, or Crimean-Congo Hemorrhagic fever.
FILED Wednesday, May 12, 2021
APPL NO 17/318329
ART UNIT 1699 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/122 (20130101) Original (OR) Class
A61K 31/165 (20130101)
A61K 31/215 (20130101)
A61K 31/341 (20130101)
A61K 31/381 (20130101)
A61K 31/454 (20130101)
A61K 31/4412 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/14 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121502 Kumar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Florida State University Research Foundation, Inc. (Tallahassee, Florida)
ASSIGNEE(S) Florida State University Research Foundation, Inc. (Tallahassee, Florida)
INVENTOR(S) Sanjay S. Kumar (Tallahassee, Florida);  Stephen Beesley (Tallahassee, Florida)
ABSTRACT D-serine is effective for inhibiting neuron loss due to an immune response by glial cells to a brain injury. An example of a method includes artificially administering a composition including D-serine to brain cells after an injury thereto, the composition including an amount of D-serine effective to inhibit death of neurons.
FILED Thursday, August 18, 2022
APPL NO 17/890342
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/0073 (20130101)
A61K 31/198 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121518 Boulares et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
ASSIGNEE(S) THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSI AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana)
INVENTOR(S) Hamid Boulares (New Orleans, Louisiana);  Mohamed Ghonim (New Orleans, Louisiana)
ABSTRACT The invention is directed to roles for low doses of PARP-1 inhibitors and synergistic combinations thereof to treat disease.
FILED Tuesday, January 14, 2020
APPL NO 16/742625
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/502 (20130101) Original (OR) Class
A61K 31/573 (20130101)
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2827 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121521 Wein et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts);  The Broad Institute, Inc. (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts);  The Broad Institute, Inc. (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Marc Wein (Boston, Massachusetts);  Henry Kronenberg (Boston, Massachusetts);  Thomas Sundberg (Boston, Massachusetts);  Ramnik Xavier (Brookline, Massachusetts);  Nathanael S. Gray (Stanford, California);  Yanke Liang (Belmont, Massachusetts);  Hwan Geun Choi (Chestnut Hill, Massachusetts);  Alykhan Shamji (Somerville, Massachusetts)
ABSTRACT The present disclosure provides methods of treating and/or preventing osteoporosis using salt-inducible kinase (SIK) inhibitors. Also provided are methods of using SIK inhibitors for increasing the function of osteocytes, increasing the number of osteoblasts, increasing the activity of osteoblasts, inhibiting the resorption of a bone, decreasing the number of osteoclasts, inhibiting the activity of osteoclasts, increasing the mass of a bone, down-regulating the expression of the gene SOST, and/or inhibiting the activity of sclerostin. The SIK inhibitors may be combined with Src inhibitors or CSF1R inhibitors. Exemplary SIK inhibitors include the compounds of the formula:
FILED Friday, January 21, 2022
APPL NO 17/581818
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/519 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/10 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121525 Rotolo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Sloan Kettering Institute for Cancer Research (New York, New York);  Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Sloan Kettering Institute for Cancer Research (New York, New York);  Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Jimmy Andrew Rotolo (Port Washington, New York);  Richard N. Kolesnick (New York, New York);  Renata Pasqualini (Los Ranchos de Albuquerque, New Mexico);  Wadih Arap (Los Ranchos de Albuquerque, New Mexico)
ABSTRACT We have discovered that administering anti-ceramide antibody treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killing and by damage to endothelial microvasculture, including radiation-induced GI syndrome, Graft vs. Host diseases, inflammatory diseases and autoimmune diseases. We have also discovered new anti-ceramide monoclonal antibodies, that have therapeutic use preferably in humanized form to treat or prevent these diseases.
FILED Tuesday, November 30, 2021
APPL NO 17/537786
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/55 (20130101) Original (OR) Class
A61K 2039/505 (20130101)

Peptides
C07K 16/28 (20130101)
C07K 16/40 (20130101)
C07K 16/44 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121526 Simard
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Maryland, Baltimore (Baltimore, Maryland);  The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia);  University of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S) J. Marc Simard (Baltimore, Maryland)
ABSTRACT The present invention concerns protection of an organ or tissue outside of the central nervous system following an ischemic episode. In particular aspects, the invention concerns organ preservation for transplantation, angina pectoris, kidney reperfusion injury, and so forth. In specific embodiments, the organ is subjected to an inhibitor of an NCCa-ATP channel that is regulated by SUR1. Exemplary inhibitors include sulfonylurea compounds, such as glibenclamide, for example.
FILED Monday, December 21, 2020
APPL NO 17/128955
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/57 (20130101) Original (OR) Class
A61K 31/64 (20130101)
A61K 31/427 (20130101)
A61K 31/565 (20130101)
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6872 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121528 Leng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Fenfei Leng (Palmetto Bay, Florida);  Eddy Alfonso (Miami, Florida);  Zifang Deng (Miami, Florida)
ASSIGNEE(S) The Florida International University Board of Trustees (Miami, Florida)
INVENTOR(S) Fenfei Leng (Palmetto Bay, Florida);  Eddy Alfonso (Miami, Florida);  Zifang Deng (Miami, Florida)
ABSTRACT The subject invention provides fluorophore-quencher nucleic acid molecules comprising relaxed or supercoiled DNA molecules, and their use in rapid and efficient high-throughput screening (HTS) assays to screen and identify compounds that inhibit DNA gyrases. These compounds can be used as antibiotics for treating bacterial infections, especially, multidrug resistant bacterial infections.
FILED Tuesday, September 13, 2022
APPL NO 17/944006
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/24 (20130101)
A61K 31/52 (20130101)
A61K 31/185 (20130101)
A61K 31/192 (20130101)
A61K 31/196 (20130101)
A61K 31/352 (20130101)
A61K 31/366 (20130101)
A61K 31/381 (20130101)
A61K 31/404 (20130101)
A61K 31/427 (20130101)
A61K 31/429 (20130101)
A61K 31/433 (20130101)
A61K 31/443 (20130101)
A61K 31/473 (20130101)
A61K 31/475 (20130101)
A61K 31/496 (20130101)
A61K 31/498 (20130101)
A61K 31/513 (20130101)
A61K 31/519 (20130101)
A61K 31/4155 (20130101)
A61K 31/4184 (20130101)
A61K 31/4196 (20130101)
A61K 31/5377 (20130101)
A61K 31/7048 (20130101) Original (OR) Class
A61K 31/7076 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121530 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) RHODE ISLAND HOSPITAL (Providence, Rhode Island);  BROWN UNIVERSITY (Providence, Rhode Island)
ASSIGNEE(S) RHODE ISLAND HOSPITAL (Providence, Rhode Island);  BROWN UNIVERSITY (Providence, Rhode Island)
INVENTOR(S) Qian Chen (Barrington, Rhode Island);  Yun Gao (Providence, Rhode Island);  John M. Sedivy (Barrington, Rhode Island);  Marco De Cecco (Pawtucket, Rhode Island)
ABSTRACT Described herein is are compositions and methods for treating an articulating joint disorders, comprising systemically administering to a subject a nucleoside reverse transcriptase inhibitor (NRTI).
FILED Monday, May 13, 2019
APPL NO 17/054409
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/675 (20130101)
A61K 31/708 (20130101) Original (OR) Class
A61K 31/7072 (20130101)
A61K 31/7076 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 19/02 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121534 Mostoslavsky et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Raul Mostoslavsky (Boston, Massachusetts);  Sita Kugel (Brookline, Massachusetts);  Anders M. Naar (Arlington, Massachusetts)
ABSTRACT It has been discovered that NAD+-dependent histone deacetylase SIRT6 is critical for suppression of PDAC by controlling the expression of Lin28b, which is a negative regulator of let-7 microRNA. Specifically, SIRT6 loss results in histone hyperacetylation at the Lin28b promoter, Myc recruitment, and pronounced induction of Lin28b and downstream let-7 target genes, HMGA2, IGF2BP1, and IGF2BP3. This invention relates generally to agents and methods of reducing expression or activity of Lin28b to treat (aggressive) PDAC in a subject.
FILED Wednesday, September 08, 2021
APPL NO 17/469530
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1135 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/34 (20130101)
C12Q 1/6886 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/50 (20130101)
G01N 33/57438 (20130101)
G01N 33/57476 (20130101)
G01N 2333/82 (20130101)
G01N 2333/98 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121562 Nabel et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) SANOFI (Paris, France)
ASSIGNEE(S) Sanofi (Paris, France)
INVENTOR(S) Gary J. Nabel (Bridgewater, New Jersey);  Chih-Jen Wei (Bridgewater, New Jersey);  Laura Nguyen (Bridgewater, New Jersey);  Kurt Swanson (Bridgewater, New Jersey);  Te-Hui Chou (Bridgewater, New Jersey)
ABSTRACT This disclosure relates to antigenic EBV polypeptides and their use in eliciting antibodies against EBV. Also disclosed are antigenic polypeptides comprising an EBV polypeptide and a ferritin protein.
FILED Monday, December 19, 2022
APPL NO 18/067940
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/162 (20130101) Original (OR) Class
A61K 47/00 (20130101)

Peptides
C07K 14/05 (20130101)
C07K 2319/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121563 Mich et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) ALLEN INSTITUTE (Seattle, Washington);  SEATTLE CHILDREN'S HOSPITAL (Seattle, Washington)
ASSIGNEE(S) Allen Institute (Seattle, Washington);  Seattle Children's Hospital (Seattle, Washington)
INVENTOR(S) John K. Mich (Seattle, Washington);  Edward Sebastian Lein (Mercer Island, Washington);  Jonathan Ting (Lake Forest Park, Washington);  Boaz P. Levi (Seattle, Washington);  Erik Hess (Issaquah, Washington);  Franck Kalume (Bothell, Washington)
ABSTRACT Selectively providing voltage-gated sodium channel function sufficient to rescue impaired Nav1.1 function to inhibitory neurons is described. Provided voltage-gated sodium channel function sufficient to rescue impaired Nav1.1 function in inhibitory neurons can be used to treat disorders such as epilepsy, and more particularly, Dravet Syndrome.
FILED Tuesday, April 09, 2019
APPL NO 17/044232
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 38/177 (20130101) Original (OR) Class
A61K 48/0058 (20130101)

Peptides
C07K 14/705 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/86 (20130101)
C12N 2750/14143 (20130101)
C12N 2830/008 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121565 Hanks et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Brent Hanks (Durham, North Carolina);  Balamayooran Theivanthiran (Durham, North Carolina)
ABSTRACT The present disclosure provides, in part, compositions and methods of increasing the efficacy of anti-PD-1/PD-L1 antibody immunotherapy in a subject. The compositions and methods comprise an NLRP3 inhibitor used in combination with a PD-1 or PD-L1 inhibitor for the treatment of cancer.
FILED Monday, September 14, 2020
APPL NO 17/020164
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/215 (20130101) Original (OR) Class
A61K 39/39541 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Peptides
C07K 16/2827 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121567 McIvor et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Regents of the University of Minnesota (Minneapolis, Minnesota);  REGENXBIO Inc. (Rockville, Maryland)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota);  REGENXBIO Inc. (Rockville, Maryland)
INVENTOR(S) R. Scott McIvor (St. Louis Park, Minnesota);  Lalitha R. Belur (St. Paul, Minnesota);  Walter Low (Shorewood, Minnesota);  Carolyn Fairbanks (St. Paul, Minnesota);  Karen Kozarsky (Bala Cynwyd, Pennsylvania)
ABSTRACT A method to prevent, inhibit or treat one or more symptoms associated with a disease of the central nervous system by intrathecally, intracerebroventricularly or endovascularly administering a rAAV encoding a gene product associated with the disease, e.g., a mammal in which the gene product is absent or present at a reduced level relative to a mammal without the disease.
FILED Wednesday, September 27, 2017
APPL NO 15/717358
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/47 (20130101) Original (OR) Class
A61K 48/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 15/86 (20130101)
C12N 2750/14143 (20130101)
C12N 2750/14171 (20130101)
C12N 2830/007 (20130101)

Enzymes
C12Y 302/01076 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121574 Chackerian et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico);  THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland);  VAXINE PTY LTD. (Bedford Park, Australia)
ASSIGNEE(S) UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico);  THE JOHNS HOPKINS UNIVERSITY (Baltimore, Massachusetts);  VAXINE PTY LTD. (Bedford Park, Australia)
INVENTOR(S) Bryce C. Chackerian (Albuquerque, New Mexico);  Fidel P. Zavala (Baltimore, Maryland);  David S. Peabody (Albuquerque, New Mexico);  Nikolai Petrovsky (Adelaide, Australia);  Lucie Jelinkova (Albuquerque, New Mexico)
ABSTRACT An immunogen useful for treating malaria generally includes an immunogenic carrier and an antigenic malaria circumsporozoite protein (CSP) peptide that includes the peptide NANPNVDPNANPNVD (SEQ ID NO:2) linked to the immunogenic carrier. The immunogen may be administered to a subject having or at risk of having malaria. Alternatively, the immunogen may be administered to an individual having or at risk of having Plasmodium falciparum blood stage parasitemia. In some cases, the immunogen can be administered in combination with another therapeutic agent for treating malaria of Plasmodium falciparum blood stage parasitemia.
FILED Tuesday, September 27, 2022
APPL NO 17/953712
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/015 (20130101) Original (OR) Class
A61K 2039/5258 (20130101)
A61K 2039/55561 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 33/06 (20180101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/63 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121595 Martin
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio)
ASSIGNEE(S) RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL (Columbus, Ohio)
INVENTOR(S) Paul Taylor Martin (Columbus, Ohio)
ABSTRACT The present disclosure relates to recombinant adeno-associated virus (rAAV) delivery of a GALGT2 polynucleotide. The disclosure provides rAAV and methods of using the rAAV for GALGT2 gene therapy of neuromuscular disorders. Exemplary neuromuscular disorders include, but are not limited to, muscular dystrophies such as Duchenne muscular dystrophy, Congenital Muscular Dystrophy 1A and Limb Girdle Muscular Dystrophy 2D.
FILED Tuesday, March 16, 2021
APPL NO 17/203232
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/45 (20130101)
A61K 48/0058 (20130101) Original (OR) Class
A61K 48/0075 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 21/00 (20180101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/1048 (20130101)
C12N 9/1051 (20130101)
C12N 15/86 (20130101)
C12N 15/8645 (20130101)
C12N 2750/14143 (20130101)
C12N 2830/008 (20130101)
C12N 2830/42 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/68 (20130101)

Enzymes
C12Y 204/01165 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121596 Achilefu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Washington University (St. Louis, Missouri)
ASSIGNEE(S)
INVENTOR(S) Samuel Achilefu (St. Louis, Missouri);  Rui Tang (St. Louis, Missouri);  Duanwen Shen (St. Louis, Missouri);  Avik Som (St. Louis, Missouri);  Baogang Xu (St. Louis, Missouri);  Gail Sudlow (St. Louis, Missouri);  Christopher Egbulefu (St. Louis, Missouri);  Partha Karmakar (St. Louis, Missouri);  Kexian Liang (St. Louis, Missouri)
ABSTRACT Provided herein is a pharmaceutical composition comprising an effective amount of cypate-Cyclo(Cys-Gly-Arg-Asp-Ser-Pro-Cys)-Lys-OH (LS301), cypate-Cyclo(Cys-Gly-Arg-Asp-Ser-Pro-Cys)-Tyr-OH (LS838) or pharmaceutically acceptable salts thereof, wherein each amino acid residue is independently in a D or L configuration; a divalent metal ion; and a pharmaceutically acceptable carrier. Further provided are lyophilized products comprising a dye-conjugate and m methods for identifying compromised and for binding phosphorylated annexin A2 (pANXA2) protein in a biological sample using a composition described herein.
FILED Thursday, June 01, 2023
APPL NO 18/327455
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0019 (20130101)
A61K 9/19 (20130101)
A61K 47/42 (20130101)
A61K 49/0034 (20130101) Original (OR) Class
A61K 49/0056 (20130101)
A61K 49/0089 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)

Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes
C09B 69/105 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121597 Li et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) King C Li (Urbana, Illinois);  Jeffrey S Moore (Savoy, Illinois)
ABSTRACT Provided herein are compositions and methods for remotely and non-invasively subjecting targeted biological structures with light emissions or chromogenic changes.
FILED Wednesday, October 16, 2019
APPL NO 16/654569
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0028 (20130101)
A61K 49/0054 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121608 Amiji et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Northeastern University (Boston, Massachusetts);  Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts);  Massachusetts Eye and Ear Infirmary (Boston, Massachusetts)
INVENTOR(S) Mansoor M. Amiji (Attleboro, Massachusetts);  Smrithi Padmakumar (Brighton, Massachusetts);  Benjamin S. Bleier (Boston, Massachusetts)
ABSTRACT A method of delivering a therapeutic agent into the central nervous system through the blood-brain barrier includes implanting an implant within the submucosal space of the olfactory epithelium. The implant can provide sustained drug delivery to the brain. The implant can be placed using a minimally invasive surgical approach.
FILED Thursday, June 03, 2021
APPL NO 17/338505
ART UNIT 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/0004 (20130101) Original (OR) Class
A61K 9/0043 (20130101)
A61K 47/34 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122730 Kwon et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ohyun Kwon (Los Angeles, California);  Andrew Smaligo (Los Angeles, California)
ABSTRACT The present disclosure relates to methods of carbon-carbon bond fragmentation.
FILED Monday, February 24, 2020
APPL NO 17/433518
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 33/00 (20130101)
C07B 37/00 (20130101) Original (OR) Class
C07B 63/04 (20130101)
C07B 2200/07 (20130101)

Acyclic or Carbocyclic Compounds
C07C 29/00 (20130101)
C07C 29/00 (20130101)
C07C 29/00 (20130101)
C07C 29/00 (20130101)
C07C 29/00 (20130101)
C07C 29/00 (20130101)
C07C 31/137 (20130101)
C07C 31/276 (20130101)
C07C 31/1355 (20130101)
C07C 35/14 (20130101)
C07C 35/32 (20130101)
C07C 41/03 (20130101)
C07C 41/03 (20130101)
C07C 43/196 (20130101)
C07C 45/28 (20130101)
C07C 45/28 (20130101)
C07C 45/28 (20130101)
C07C 45/28 (20130101)
C07C 45/28 (20130101)
C07C 45/40 (20130101)
C07C 45/40 (20130101)
C07C 45/64 (20130101)
C07C 45/64 (20130101)
C07C 45/673 (20130101)
C07C 45/673 (20130101)
C07C 45/673 (20130101)
C07C 45/673 (20130101)
C07C 49/497 (20130101)
C07C 49/497 (20130101)
C07C 49/513 (20130101)
C07C 49/517 (20130101)
C07C 49/517 (20130101)
C07C 49/517 (20130101)
C07C 49/637 (20130101)
C07C 49/637 (20130101)
C07C 49/713 (20130101)
C07C 67/00 (20130101)
C07C 67/00 (20130101)
C07C 67/39 (20130101)
C07C 67/39 (20130101)
C07C 67/39 (20130101)
C07C 67/39 (20130101)
C07C 67/39 (20130101)
C07C 67/39 (20130101)
C07C 67/333 (20130101)
C07C 67/333 (20130101)
C07C 69/16 (20130101)
C07C 69/24 (20130101)
C07C 69/74 (20130101)
C07C 69/738 (20130101)
C07C 69/753 (20130101)
C07C 69/757 (20130101)
C07C 69/757 (20130101)
C07C 315/02 (20130101)
C07C 315/02 (20130101)
C07C 315/02 (20130101)
C07C 317/22 (20130101)
C07C 317/24 (20130101)
C07C 319/14 (20130101)
C07C 319/14 (20130101)
C07C 319/14 (20130101)
C07C 319/14 (20130101)
C07C 319/14 (20130101)
C07C 321/28 (20130101)
C07C 323/18 (20130101)
C07C 323/22 (20130101)
C07C 323/63 (20130101)
C07C 2601/02 (20170501)
C07C 2601/04 (20170501)
C07C 2601/10 (20170501)
C07C 2601/14 (20170501)
C07C 2602/08 (20170501)
C07C 2602/26 (20170501)
C07C 2602/28 (20170501)
C07C 2602/46 (20170501)
C07C 2603/74 (20170501)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/1892 (20130101)
C07F 9/5325 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122769 Trend et al.
FUNDED BY
Department of Health and Human Services (HHS)
Assistant Secretary for Preparedness and Response (ASPR)
Biomedical Advanced Research and Development Authority (BARDA)
APPLICANT(S) Cipla USA, Inc. (Warren, New Jersey)
ASSIGNEE(S) CIPLA USA, INC. (Warren, New Jersey)
INVENTOR(S) Raissa Trend (Warren, New Jersey);  Michael Dappen (Warren, New Jersey);  Christopher E. Henry (Warren, New Jersey);  Adam Aaron Goldblum (Warren, New Jersey);  James Bradley Aggen (Warren, New Jersey);  Ricardo Filipe De Jesus Gonçalves Mendonça (Warren, New Jersey);  João Carlos Falcão Sardinha (Warren, New Jersey)
ABSTRACT The present disclosure relates to novel methods for preparing antibacterial aminoglycoside compounds, as well as to related intermediates, and crystal forms thereof, useful in such methods.
FILED Thursday, August 04, 2022
APPL NO 17/881462
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
General Methods of Organic Chemistry; Apparatus Therefor
C07B 2200/13 (20130101)

Heterocyclic Compounds
C07D 407/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122771 Boateng
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
APPLICANT(S) HIGH POINT UNIVERSITY (High Point, North Carolina)
ASSIGNEE(S) High Point University (High Point, North Carolina)
INVENTOR(S) Comfort Ahenkan Boateng (High Point, North Carolina)
ABSTRACT The disclosure provides compounds which exhibit dopamine receptor antagonist activity and which may be useful as therapeutic agents for the treatment of diseases and disorders associated with dopamine receptors. Also provided are methods for the preparation of such compounds, pharmaceutical compositions comprising the disclosed compounds, and methods for treating diseases or disorders with such compounds or pharmaceutical compositions.
FILED Friday, February 18, 2022
APPL NO 17/675696
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/30 (20180101)

Heterocyclic Compounds
C07D 417/06 (20130101)
C07D 417/14 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122799 Dowd et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (Washington, District of Columbia);  WASHINGTON UNIVERSITY (St. Louis, Missouri)
ASSIGNEE(S) THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (Washington, District of Columbia);  WASHINGTON UNIVERSITY (St. Louis, Missouri)
INVENTOR(S) Cynthia Dowd (Washington, District of Columbia);  Audrey Odom John (St. Louis, Missouri);  Rachel Edwards (St. Louis, Missouri);  Kenneth M. Heidel (Washington, District of Columbia);  Xu Wang (Exton, Pennsylvania);  Rene Chofor (Washington, District of Columbia)
ABSTRACT The present disclosure provides method of treating or preventing a microbial infection caused by a prokaryotic pathogen in a subject, the method comprising administering a compound of Formula (I) as set forth in the specification. In one embodiment, the prokaryotic pathogen belongs to the genus Staphylococcus.
FILED Tuesday, June 18, 2019
APPL NO 17/253841
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/04 (20180101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 9/4009 (20130101)
C07F 9/4015 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122807 Kawaoka et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
Centers of Excellence for Influenza Research and Surveillance (CEIRS)
APPLICANT(S) Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin)
INVENTOR(S) Yoshihiro Kawaoka (Middleton, Wisconsin);  Gabriele Neumann (Madison, Wisconsin);  Jihui Ping (Nanjing, China PRC)
ABSTRACT An isolated recombinant influenza virus is provided having PA, PB1, PB2, NP, NS, M, NA and HA viral segments, wherein the PB1 viral segment encodes a PB1 with a residue other than isoleucine at position 711 or the M viral segment encodes a M1 with a residue other than methionine at position 128, wherein the recombinant influenza virus has enhanced replication relative to a corresponding influenza virus having a PB1 viral segment that encodes a PB1 with an isoleucine at position 711 or having a M viral segment that encodes a M1 with methionine at position 128, as well as methods of making and using the virus.
FILED Monday, July 18, 2022
APPL NO 17/813200
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/007 (20130101)
A61K 9/0019 (20130101)
A61K 39/145 (20130101)
A61K 2039/54 (20130101)
A61K 2039/544 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/16 (20180101)

Peptides
C07K 14/005 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 2760/16121 (20130101)
C12N 2760/16122 (20130101)
C12N 2760/16134 (20130101)
C12N 2760/16152 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122811 Stupp et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Samuel I. Stupp (Chicago, Illinois);  Alexandra N. Kolberg (Chicago, Illinois);  Zaida Alvarez (Chicago, Illinois)
ABSTRACT Provided herein are peptide amphiphiles (PAs) and supramolecular PA nanostructures that mimic brain derived neurotrophic factor (BDNF), a growth factor that induces neuronal survival, maturation, and increased electrical activity. In particular, injectable biomaterials comprising BDNF mimetic PAs are provided, as well as methods of using BDNF mimetic PAs for the treatment or prevention of neurological injuries, diseases, and disorders.
FILED Friday, April 05, 2019
APPL NO 17/045728
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Peptides
C07K 7/64 (20130101)
C07K 14/475 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122819 Antipov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Silver Creek Pharmaceuticals, Inc. (San Francisco, California)
ASSIGNEE(S) Silver Creek Pharmaceuticals, Inc. (San Francisco, California)
INVENTOR(S) Laura D. J. Antipov (Oakland, California);  Shawdee Eshghi (Oakland, California);  Kristopher M. Kuchenbecker (Phoenix, Arizona);  Bjorn L. Millard (Orinda, California);  Matthew D. Onsum (El Cerrito, California);  Andrea D. Nickerson (San Francisco, California);  Timothy R. Stowe (San Francisco, California);  Yan Zhang (San Francisco, California)
ABSTRACT Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue.
FILED Thursday, February 10, 2022
APPL NO 17/668825
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/47 (20130101)
C07K 14/65 (20130101) Original (OR) Class
C07K 14/765 (20130101)
C07K 2319/33 (20130101)
C07K 2319/035 (20130101)
C07K 2319/75 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122820 Riley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania)
ASSIGNEE(S) The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) James L. Riley (Downingtown, Pennsylvania);  Rachel Leibman (Philadelphia, Pennsylvania);  Aimee S. Payne (Merion Station, Pennsylvania);  Christoph T. Ellebrecht (Philadelphia, Pennsylvania);  Michael C. Milone (Cherry Hill, New Jersey)
ABSTRACT The present invention relates to compositions and methods for treating of a HIV infected mammal using a CD4 membrane-bound chimeric receptor or a HIV specific scFvs CARs. One aspect includes a modified T cell and pharmaceutical compositions comprising the modified cells for adoptive cell therapy and treating a disease or condition associated with HIV infection.
FILED Friday, August 07, 2020
APPL NO 16/988415
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/17 (20130101)
A61K 38/1774 (20130101)
A61K 39/42 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)
A61K 2039/572 (20130101)
A61K 2039/5158 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/18 (20180101)

Peptides
C07K 14/7051 (20130101)
C07K 14/70514 (20130101) Original (OR) Class
C07K 14/70517 (20130101)
C07K 14/70521 (20130101)
C07K 14/70578 (20130101)
C07K 16/1045 (20130101)
C07K 2317/21 (20130101)
C07K 2317/24 (20130101)
C07K 2317/76 (20130101)
C07K 2317/622 (20130101)
C07K 2319/00 (20130101)
C07K 2319/02 (20130101)
C07K 2319/03 (20130101)
C07K 2319/30 (20130101)
C07K 2319/33 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122843 Ho et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Mitchell Ho (Urbana, Maryland);  Nan Li (Laurel, Maryland);  Jiajia Pan (Rockville, Maryland)
ABSTRACT Monoclonal antibodies that specifically bind glypican-1 (GPC1) are described. Chimeric antigen receptor (CAR) T cells, immunotoxins and other antibody conjugates based on the GPC1-specific antibodies are also described. The disclosed CAR T cells, immunotoxins, GPC1-specific antibodies and conjugates thereof can be used, for example, in the diagnosis or treatment of GPC1-positive pancreatic cancer and other cancers.
FILED Wednesday, January 15, 2020
APPL NO 17/422609
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/6829 (20170801)
A61K 47/6929 (20170801)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)

Peptides
C07K 14/4725 (20130101)
C07K 16/303 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122996 Ismagilov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
ASSIGNEE(S) CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California)
INVENTOR(S) Rustem F. Ismagilov (Pasadena, California);  Eugenia Khorosheva (Pasadena, California);  Dmitriy V. Zhukov (Pasadena, California)
ABSTRACT A device for allowing compartmentalized reactions with minimized cross-contamination between the compartments, utilizing a delivery of material by loading wells to pooling wells, such that the pooling wells can be additively provided with reactants while maintaining isolation between the pooling wells. The use of geometric properties is used to facilitate transmission of fluids/droplets without the need for hydrophilic surfaces.
FILED Tuesday, September 25, 2018
APPL NO 16/141707
ART UNIT 1675 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 3/502738 (20130101)
B01L 2200/16 (20130101)
B01L 2200/027 (20130101)
B01L 2200/141 (20130101)
B01L 2300/161 (20130101)
B01L 2300/0816 (20130101)
B01L 2300/0861 (20130101)
B01L 2400/065 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1065 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6806 (20130101)
C12Q 1/6806 (20130101)
C12Q 1/6855 (20130101)
C12Q 2523/101 (20130101)
C12Q 2525/191 (20130101)
C12Q 2565/514 (20130101)

Combinatorial Chemistry; Libraries, e.g Chemical Libraries
C40B 30/04 (20130101)
C40B 40/08 (20130101)
C40B 70/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/58 (20130101)
G01N 33/68 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122997 Khalili et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Temple University Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
ASSIGNEE(S) Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania)
INVENTOR(S) Kamel Khalili (Bala Cynwyd, Pennsylvania);  Wenhui Hu (Cherry Hill, New Jersey)
ABSTRACT Compositions for the in vivo delivery of a gene editing CRISPR/Cas9 complex was developed to eliminate integrated retroviral DNA sequences from latently infected human cells and animal disease models.
FILED Monday, February 13, 2017
APPL NO 15/998558
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 2227/105 (20130101)
A01K 2267/0337 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 48/00 (20130101)

Peptides
C07K 2319/09 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101) Original (OR) Class
C12N 15/1132 (20130101)
C12N 2310/20 (20170501)
C12N 2750/14143 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123005 Iavarone et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Trustees of Columbia University in the City of New York (New York, New York)
ASSIGNEE(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
INVENTOR(S) Antonio Iavarone (New York, New York);  Anna Lasorella (New York, New York);  Raul Rabadan (New York, New York)
ABSTRACT The invention discloses oncogenic fusion proteins. The invention provides methods for treating gene-fusion based cancers.
FILED Wednesday, July 10, 2019
APPL NO 16/508021
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Peptides
C07K 14/47 (20130101)
C07K 14/71 (20130101)
C07K 14/82 (20130101)
C07K 16/18 (20130101)
C07K 16/2863 (20130101)
C07K 2319/00 (20130101)
C07K 2319/73 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/12 (20130101)
C12N 15/62 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/158 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/57492 (20130101)
G01N 2333/91205 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123019 Theunissen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
ASSIGNEE(S) Whitehead Institute for Biomedical Research (Cambridge, Massachusetts);  Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Thorold W Theunissen (Belmont, Massachusetts);  Nathanael S. Gray (Boston, Massachusetts);  Rudolf Jaenisch (Brookline, Massachusetts)
ABSTRACT The present disclosure provides compounds of any one of Formulae (A) to (L). The present disclosure also provides compositions, uses, and methods that include or involve a compound described herein, a serine/threonine-protein kinase B-Raf (BRAF) inhibitor, an epidermal growth factor receptor (EGFR) inhibitor, a vascular endothelial growth factor 1 (VEGFR1) inhibitor, a fibroblast growth factor receptor 1 (FGFR1) inhibitor, or a combination thereof. The compounds, compositions, uses, and methods are useful in changing the pluripotency state of a vertebrate cell to a more naïve state.
FILED Thursday, October 15, 2020
APPL NO 17/071627
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0606 (20130101) Original (OR) Class
C12N 5/0696 (20130101)
C12N 2501/11 (20130101)
C12N 2501/115 (20130101)
C12N 2501/165 (20130101)
C12N 2501/727 (20130101)
C12N 2501/999 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123020 Chou et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania);  NEW YORK BLOOD CENTER, INC. (New York, New York)
ASSIGNEE(S) The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania);  New York Blood Center, Inc. (New York, New York)
INVENTOR(S) Stella Chou (Bryn Mawr, Pennsylvania);  Connie Westhoff (New York, New York)
ABSTRACT Provided herein are engineered red blood cells expressing rare blood antigen group profiles, and methods of making use the same, are described. Also provided are recombinant reagent red blood cells that express or lack the expression of at least one protein (e.g., a blood group antigen) on its surface and uses thereof.
FILED Tuesday, June 06, 2023
APPL NO 18/330167
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 35/14 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0634 (20130101) Original (OR) Class
C12N 9/22 (20130101)
C12N 15/111 (20130101)
C12N 2310/20 (20170501)
C12N 2510/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/80 (20130101)
G01N 33/6854 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123026 Aisenbrey et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin)
INVENTOR(S) Elizabeth Anne Aisenbrey (Madison, Wisconsin);  William Leo Murphy (Waunakee, Wisconsin);  Elizabeth Emma Torr (Madison, Wisconsin);  Victoria Harms (Madison, Wisconsin);  Gaurav Kaushik (Madison, Wisconsin)
ABSTRACT The present invention relates to substantially planar vascularized brain cancer organoid and methods of using such vascularized brain cancer organoids in anti-cancer drug discovery screen. In particular, provided herein are methods of producing and using complex, highly uniform vascularized brain cancer organoids that comprise physiologically relevant human cells and have the high degree of sample uniformity and reproducibility required for use in high-throughput screening applications.
FILED Thursday, March 26, 2020
APPL NO 16/831017
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0693 (20130101) Original (OR) Class
C12N 2500/50 (20130101)
C12N 2501/734 (20130101)
C12N 2501/998 (20130101)
C12N 2502/28 (20130101)
C12N 2502/30 (20130101)
C12N 2502/086 (20130101)
C12N 2502/088 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123032 Zhang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) The Broad Institute, Inc. (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts);  MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Feng Zhang (Cambridge, Massachusetts);  Linyi Gao (Cambridge, Massachusetts);  Bernd Zetsche (Cambridge, Massachusetts);  Ian Slaymaker (Cambridge, Massachusetts)
ABSTRACT Disclosed and claimed are mutation(s) or modification(s) of the CRISPR enzyme, for example a Cas enzyme such as a Cas9, which obtain an improvement, for instance a reduction, as to off-target effects of a CRISPR-Cas or CRISPR-enzyme or CRISPR-Cas9 system or complex containing or including such a mutated or modified Cas or CRISPR enzyme or Cas9. Methods for making and using and uses of such mutated or modified Cas or CRISPR enzyme or Cas9 and systems or complexes containing the same and products from such methods and uses are also disclosed and claimed.
FILED Tuesday, November 26, 2019
APPL NO 16/697018
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 2319/09 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101) Original (OR) Class
C12N 15/111 (20130101)
C12N 15/902 (20130101)
C12N 2310/20 (20170501)

Enzymes
C12Y 301/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123840 Ros et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Alexandra Ros (Phoenix, Arizona);  Daihyun Kim (Mesa, Arizona);  Austin Echelmeier (Tempe, Arizona);  Jorvani Cruz Villarreal (Tempe, Arizona);  Ana Egatz-Gomez (Phoenix, Arizona);  Sebastian Quintana (Phoenix, Arizona)
ABSTRACT Methods and systems are provided for serial femtosecond crystallography for reducing the vast amount of waste of injected crystals practiced with traditional continuous flow injections. A micrometer-scale 3-D printed water-in-oil droplet generator device includes an oil phase inlet channel, an aqueous phase inlet channel, a droplet flow outlet channel, and two embedded non-contact electrodes. The inlet and outlet channels are connected internally at a junction. The electrodes comprise gallium metal injected within the 3-D printed device. Voltage across the electrodes generates water-in-oil droplets, determines a rate for a series of droplets, or triggers a phase shift in the droplets. An external trigger generates the droplets based on the frequency of an XFEL utilized in droplet detection, thereby synchronizing a series of droplets with x-ray pulses for efficient crystal detection. The generated droplets can be coupled to an SFX with XFEL experiment compatible with common liquid injector such as a GDVN.
FILED Tuesday, November 07, 2023
APPL NO 18/504091
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/0241 (20130101)
B01L 3/50273 (20130101)
B01L 2300/0867 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/20025 (20130101) Original (OR) Class
G01N 2223/602 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123874 Schwartz et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) CELL IDX, INC. (San Diego, California);  THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
ASSIGNEE(S) CELL IDX, INC. (San Diego, California);  THE UNIVERSITY OF CHICAGO (Chicago, Illinois)
INVENTOR(S) David A. Schwartz (Encinitas, California);  Stephen J. Kron (Oak Park, Illinois)
ABSTRACT The instant disclosure provides reagent compounds, and antibody and oligonucleotide reagents, for use in a variety of assays, including immunoassays and nucleic acid hybridizations. The reagent compounds comprise a bridging antigen or bridging oligonucleotide and a latent crosslinker moiety, such as a tyramide moiety. The bridging antigens are recognizable by the antibody of a corresponding antibody reagent with high affinity, and the bridging oligonucleotides are complementary to the oligonucleotide of a corresponding oligonucleotide reagent. The antibody reagents and oligonucleotide reagents also comprise a crosslinker activation agent, such as a peroxidase enzyme. Reaction of the reagent compounds with the crosslinker activation agent results in the amplification of signal in assays for target cellular markers, including cellular antigens and nucleic acids. Also provided are detectable antibodies specific for the bridging antigens, kits comprising the reagent compounds and antibody and oligonucleotide reagents, methods of signal amplification using the compounds and reagents of the disclosure, methods of preparation of the compounds and reagents, and compositions comprising the compounds and reagents.
FILED Tuesday, July 18, 2017
APPL NO 16/318793
ART UNIT 1678 — Fluid Handling and Dispensing
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/0006 (20130101)
C12N 9/16 (20130101)
C12N 9/0065 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/682 (20130101)
C12Q 1/682 (20130101)
C12Q 1/6804 (20130101)
C12Q 1/6804 (20130101)
C12Q 2531/101 (20130101)
C12Q 2531/101 (20130101)
C12Q 2531/125 (20130101)
C12Q 2531/125 (20130101)
C12Q 2543/101 (20130101)
C12Q 2543/101 (20130101)

Enzymes
C12Y 101/03004 (20130101)
C12Y 111/01007 (20130101)
C12Y 301/03001 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/533 (20130101)
G01N 33/535 (20130101)
G01N 33/547 (20130101) Original (OR) Class
G01N 33/54353 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123881 Wandinger-Ness et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) UNM Rainforest Innovations (Albuquerque, New Mexico)
ASSIGNEE(S) UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico)
INVENTOR(S) Angela Wandinger-Ness (Albuquerque, New Mexico);  Tione Buranda (Albuquerque, New Mexico);  Peter Simons (Albuquerque, New Mexico);  Stephen Young (Albuquerque, New Mexico)
ABSTRACT The present invention is directed to the discovery that RapI-GTP, Rac1-GTP and Flt3-L can be used as Biomarkers for the early detection of sepsis in patients suspected of a bacterial infection which presents as sepsis or is likely to produce sepsis. In particular, the present invention is directed to methods, assays and kits which may be used to distinguish sepsis (infection) from systematic inflammatory response caused by sterile inflammation in trauma patients. The method may be used to diagnose bacteria infection and/or sepsis and monitor therapy of a patient to allow modification of treatment and/or cessation of treatment.
FILED Thursday, April 18, 2019
APPL NO 17/048941
ART UNIT 1678 — Fluid Handling and Dispensing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/14 (20130101)
G01N 33/563 (20130101)
G01N 33/588 (20130101)
G01N 33/6893 (20130101) Original (OR) Class
G01N 2800/26 (20130101)
G01N 2800/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12125204 Bradley
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Infotech Soft, Inc. (Miami, Florida)
ASSIGNEE(S) Infotech Soft, Inc. (Miami, Florida)
INVENTOR(S) Ray Mathew Bradley (Miami, Florida)
ABSTRACT A computer implemented method and system for identifying and visualizing features correlated with cancer subtypes, includes the steps of receiving a set of medical images representing an area including a patient's lesion, applying a classification model trained on lesions with known pathology by mathematically combining the model's learned weights with said medical images to produce a score indicating the likelihood of the lesion being of each particular cancer subtype, extracting importance maps from said classification model indicating features correlated with each cancer subtype by tracing the output of the model through the learned weights to identify regions of the input with a strong influence on the classification score for each cancer subtype, and displaying said importance maps visually on a computing device.
FILED Thursday, June 09, 2022
APPL NO 17/836555
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/30096 (20130101)

Image or Video Recognition or Understanding
G06V 10/82 (20220101)
G06V 10/462 (20220101)
G06V 10/762 (20220101)
G06V 10/778 (20220101)
G06V 10/811 (20220101)
G06V 10/7715 (20220101)
G06V 10/7747 (20220101)
G06V 20/20 (20220101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
G16H 50/70 (20180101)
G16H 70/60 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12125691 Cooks et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana);  Alan Keith Jarmusch (Lafayette, Indiana);  Valentina Pirro (West Lafayette, Indiana)
ABSTRACT The invention generally relates to systems and methods for sample analysis using swabs. In certain aspects, the invention provides systems that include a probe having a conductive proximal portion coupled to a porous material at a distal portion of the probe that is configured to retain a portion of a sample that has contacted the porous material, and a mass spectrometer having an inlet. The system is configured such that the porous material at a distal portion of the probe is aligned over the inlet of the mass spectrometer.
FILED Friday, June 09, 2023
APPL NO 18/208116
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/7282 (20130101)
A61B 5/14503 (20130101)
A61B 10/02 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 13/38 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 30/72 (20130101)
G01N 2001/028 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/165 (20130101)
H01J 49/0409 (20130101)
H01J 49/0459 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12127324 Shumlak et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) ZAP ENERGY, INC. (Seattle, Washington)
ASSIGNEE(S) Zap Energy, Inc. (Everett, Washington)
INVENTOR(S) Uri Shumlak (Seattle, Washington);  Brian A. Nelson (Edmonds, Washington);  Eric T. Meier (Seattle, Washington)
ABSTRACT Methods and systems are provided for plasma confinement utilizing various electrode and valve configurations. In one example, a device includes a first electrode positioned to define an outer boundary of an acceleration volume, a second electrode arranged coaxially with respect to the first electrode and positioned to define an inner boundary of the acceleration volume, at least one power supply to drive an electric current along a Z-pinch plasma column between the first second electrodes, and a set of valves to provide gas to the acceleration volume to fuel the Z-pinch plasma column, wherein an electron flow of the electric current is in a first direction from the second electrode to the first electrode. In additional or alternative examples, a shaping part is conductively connected to the second electrode to, in a presence of the gas, cause a gas breakdown of the gas to generate a sheared flow velocity profile.
FILED Friday, May 27, 2022
APPL NO 17/827379
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Fusion Reactors
G21B 1/05 (20130101)
G21B 1/21 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/06 (20130101) Original (OR) Class
H05H 1/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 12121355 Yeo
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Woon-Hong Yeo (Atlanta, Georgia)
ABSTRACT An exemplary embodiment of the present disclosure provides a method of determining stress levels in a user comprising: receiving galvanic skin response (GSR) measurements by a wearable sensor on the user over a period of time; receiving temperature measurements by the wearable sensor on the user over the period of time; determining changes in the temperature over a predetermined threshold in the temperature measurements over the period of time; calibrating the GSR measurements based on the determined changes in temperature over the predetermined threshold; calculating a stress level of the user based on the calibrated GSR measurements; and generating an output indicative of the calculated stress level.
FILED Friday, January 28, 2022
APPL NO 17/587353
ART UNIT 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/01 (20130101)
A61B 5/0004 (20130101)
A61B 5/165 (20130101) Original (OR) Class
A61B 5/0533 (20130101)
A61B 5/681 (20130101)
A61B 5/742 (20130101)
A61B 5/6826 (20130101)
A61B 5/6898 (20130101)
A61B 5/7278 (20130101)
A61B 2560/0223 (20130101)
A61B 2560/0431 (20130101)
A61B 2562/164 (20130101)
A61B 2562/0209 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121534 Mostoslavsky et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Raul Mostoslavsky (Boston, Massachusetts);  Sita Kugel (Brookline, Massachusetts);  Anders M. Naar (Arlington, Massachusetts)
ABSTRACT It has been discovered that NAD+-dependent histone deacetylase SIRT6 is critical for suppression of PDAC by controlling the expression of Lin28b, which is a negative regulator of let-7 microRNA. Specifically, SIRT6 loss results in histone hyperacetylation at the Lin28b promoter, Myc recruitment, and pronounced induction of Lin28b and downstream let-7 target genes, HMGA2, IGF2BP1, and IGF2BP3. This invention relates generally to agents and methods of reducing expression or activity of Lin28b to treat (aggressive) PDAC in a subject.
FILED Wednesday, September 08, 2021
APPL NO 17/469530
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101) Original (OR) Class

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/1135 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/34 (20130101)
C12Q 1/6886 (20130101)
C12Q 2600/106 (20130101)
C12Q 2600/156 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/50 (20130101)
G01N 33/57438 (20130101)
G01N 33/57476 (20130101)
G01N 2333/82 (20130101)
G01N 2333/98 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121879 Guliashvili et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Development Command (USAMRDC)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) CytoSorbents Corporation (Monmouth Junction, New Jersey)
ASSIGNEE(S) CytoSorbents, Inc. (Princeton, New Jersey)
INVENTOR(S) Tamaz Guliashvili (Monmouth Junction, New Jersey);  Maryann Gruda (Monmouth Junction, New Jersey);  Thomas Golobish (Monmouth Junction, New Jersey);  David James (Monmouth Junction, New Jersey);  Karl-Gustav Ruggeberg (Monmouth Junction, New Jersey);  Pamela O'Sullivan (Monmouth Junction, New Jersey);  Sarah Patterson (Monmouth Junction, New Jersey)
ABSTRACT The invention concerns polymeric media based on modified natural polysaccharides for removing one or both of Anti-A Antibodies and Anti-B Antibodies from human blood or plasma, the media comprising one or both of (i) a polymeric solid support with a blood group A Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions, and (ii) a polymeric solid support with a blood group B Antigen ligand attached to the solid support at a ligand loading between 1-5 mg/mL of solid support, and wherein the media is stable under physiological pH conditions.
FILED Monday, December 02, 2019
APPL NO 17/298968
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 15/3809 (20130101)

Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/3212 (20130101)
B01J 20/3274 (20130101) Original (OR) Class
B01J 20/28019 (20130101)
B01J 20/28078 (20130101)

Peptides
C07K 1/22 (20130101)
C07K 16/065 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121889 Herdy, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
APPLICANT(S) CFD RESEARCH CORPORATION (Huntsville, Alabama);  Garry Lynn Freeman, Jr. (Huntsville, Alabama)
ASSIGNEE(S) CFD RESEARCH CORPORATION (Huntsville, Alabama);  Garry Lynn Freeman, Jr. (Huntsville, Alabama)
INVENTOR(S) Joseph Roger Herdy, Jr. (Huntsville, Alabama);  Garry Lynn Freeman, Jr. (Huntsville, Alabama)
ABSTRACT A variable 3D CD nozzle includes: a flexible body defining a flow path having an inlet extending through a narrowed throat to an expanded outlet, wherein the flexible body comprises a plurality of flexible members movably interconnected together; and at least one means for changing a shape of the flexible body to change a dimension or location of the throat plane relative to at least one of the inlet plane or outlet plane. A method of changing airflow in a nozzle includes operating at least one means for changing the shape of the flexible nozzle body to change the dimension or the location of the throat plane. A method of testing an object includes placing a test object in the test region of the test cell and passing a test gas from the outlet opening of the nozzle onto the test object.
FILED Friday, October 15, 2021
APPL NO 17/502517
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 4/002 (20130101) Original (OR) Class
B01J 6/00 (20130101)
B01J 2204/007 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 13/0203 (20130101)
C01B 21/02 (20130101)

Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for
G01M 9/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121900 Han et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
APPLICANT(S) THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
ASSIGNEE(S) THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas)
INVENTOR(S) Arum Han (College Station, Texas);  Adrian Guzman (College Station, Texas);  Han Zhang (College Station, Texas);  Jose Wippold (College Station, Texas);  Jing Dai (College Station, Texas)
ABSTRACT A combination micro/macro-fluidic analysis system with one or more of a droplet transition unit, a droplet cleaving unit, a droplet synchronization, and a merging unit to enable highly efficient complex droplet microfluidic assays.
FILED Monday, October 23, 2023
APPL NO 18/382591
ART UNIT 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502784 (20130101) Original (OR) Class
B01L 2200/12 (20130101)
B01L 2200/16 (20130101)
B01L 2200/027 (20130101)
B01L 2200/0647 (20130101)
B01L 2400/086 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121901 DeJohn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Biomeme, Inc. (Philadelphia, Pennsylvania)
ASSIGNEE(S) Biomeme, Inc. (Philadelphia, Pennsylvania)
INVENTOR(S) Marc Dominic DeJohn (Philadelphia, Pennsylvania);  Tom Welsh (Philadelphia, Pennsylvania);  Luke Gary (Philadelphia, Pennsylvania)
ABSTRACT The present disclosure provides devices, systems, methods for processing and/or analyzing a biological sample. An analytic device for processing and/or analyzing a biological sample may comprise a moving carriage. The analytic device may be portable. The analytic device may receive instructions for performing an assay from a mobile electronic device external to a housing of the analytic device.
FILED Friday, June 12, 2020
APPL NO 16/899810
ART UNIT 1796 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 1/52 (20190801)
B01L 3/50851 (20130101)
B01L 7/52 (20130101) Original (OR) Class
B01L 2200/16 (20130101)
B01L 2300/023 (20130101)
B01L 2300/1861 (20130101)
B01L 2400/0442 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/645 (20130101)
G01N 2201/0221 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122493 Seeley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
INVENTOR(S) Eric Seeley (Seebeck, Washington);  Jacob Snow (Bremerton, Washington)
ABSTRACT A surface vehicle comprising modular elements and attachable components, including a male end adapted to join a single-piece female end by rotating the male end into the single-piece female end such that data bus terminals align and power bus terminals align. The vehicle can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed vehicles for each mission. The joints connecting the modules are designed such that power and data connections between modules are reliably made.
FILED Monday, July 10, 2023
APPL NO 18/220202
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers
B63G 8/001 (20130101)
B63G 8/04 (20130101) Original (OR) Class
B63G 2008/002 (20130101)

Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 12/91 (20130101)
H01R 12/7005 (20130101)
H01R 13/64 (20130101)
H01R 13/641 (20130101)
H01R 13/6205 (20130101)
H01R 13/7175 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122494 Seeley et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
INVENTOR(S) Eric Seeley (Seebeck, Washington);  Jacob Snow (Bremerton, Washington)
ABSTRACT A module joining system comprising modular elements and attachable components, including a male end adapted to join a single-piece female end by rotating the male end into the single-piece female end such that data bus terminals align and power bus terminals align. The system can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed systems for each mission. The joints connecting the modules are designed such that power and data connections between modules are reliably made.
FILED Tuesday, July 11, 2023
APPL NO 18/220311
ART UNIT 2831 — Electrical Circuits and Systems
CURRENT CPC
Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers
B63G 8/001 (20130101)
B63G 8/04 (20130101) Original (OR) Class
B63G 2008/002 (20130101)

Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors
H01R 12/91 (20130101)
H01R 12/7005 (20130101)
H01R 13/64 (20130101)
H01R 13/641 (20130101)
H01R 13/6205 (20130101)
H01R 13/7175 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122674 Dietz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
Naval Air Warfare Center Aircraft Division (NAWCAD)
Naval Air Warfare Center (NAWC)
APPLICANT(S) TDA Research, Inc (Wheat Ridge, Colorado)
ASSIGNEE(S) TDA Research, Inc. (Golden, Colorado)
INVENTOR(S) Steven Dean Dietz (Denver, Colorado);  Jeremy Noce (Lakewood, Colorado)
ABSTRACT An activated carbon-coated carbon black material having a nitrogen BET surface area of about 850 to 1800 m2/g, a packing density of at least 0.8 g/cc as determined at a compressive force of 500 kgf/cm2 on dry carbon powder, an electrical conductivity of a least 10 S/cm at a compressive force of 500 kgf/cm2 on dry carbon powder and electrodes and batteries comprising the carbon material. Methods for preparing such carbon materials from sugar, dextrose, oils and carbon black are described. The material is comprised of carbon black particles coated with a porous activated carbon shell.
FILED Monday, May 04, 2020
APPL NO 17/609737
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 32/05 (20170801) Original (OR) Class

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2006/10 (20130101)
C01P 2006/12 (20130101)
C01P 2006/40 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/583 (20130101)
H01M 10/052 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122843 Ho et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Mitchell Ho (Urbana, Maryland);  Nan Li (Laurel, Maryland);  Jiajia Pan (Rockville, Maryland)
ABSTRACT Monoclonal antibodies that specifically bind glypican-1 (GPC1) are described. Chimeric antigen receptor (CAR) T cells, immunotoxins and other antibody conjugates based on the GPC1-specific antibodies are also described. The disclosed CAR T cells, immunotoxins, GPC1-specific antibodies and conjugates thereof can be used, for example, in the diagnosis or treatment of GPC1-positive pancreatic cancer and other cancers.
FILED Wednesday, January 15, 2020
APPL NO 17/422609
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 47/6829 (20170801)
A61K 47/6929 (20170801)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/04 (20180101)

Peptides
C07K 14/4725 (20130101)
C07K 16/303 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122975 Bailey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Novum Nano, LLC (Rapid City, South Dakota);  South Dakota Board of Regents (Pierre, South Dakota)
ASSIGNEE(S) Novum Nano, LLC (Rapid City, South Dakota);  South Dakota Board of Regents (Pierre, South Dakota)
INVENTOR(S) Craig Bailey (Rapid City, South Dakota);  Greg Christensen (Hermosa, South Dakota);  Haiping Hong (Rapid City, South Dakota)
ABSTRACT An engine oil additive includes carbon nanotubes and boron nitride particulates dispersed within a fluid. The additive is configured to be mixed with a quantity of oil such that the quantity of oil has a concentration from 0.05 to 0.5 grams of carbon nanotubes and of boron nitride particulates per quart of oil to improve the lubricity of the oil. The additive improves the horsepower and torque of the engine while reducing fuel consumption. The carbon nanotubes have an —OH functionalized exterior surface. The carbon nanotubes have a diameter from 1 nanometer to 50 nanometers and have a length from 1 micron to 1000 microns. The boron nitride particulates are hex-boron nitride structures having an average size from 30 nanometers to 500 nanometers.
FILED Monday, April 04, 2022
APPL NO 17/713053
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition
C10M 125/02 (20130101)
C10M 125/26 (20130101)
C10M 169/04 (20130101) Original (OR) Class
C10M 2201/14 (20130101)
C10M 2201/041 (20130101)
C10M 2201/082 (20130101)
C10M 2203/003 (20130101)

Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions
C10N 2020/06 (20130101)
C10N 2040/25 (20130101)
C10N 2070/02 (20200501)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123097 Huang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Northwestern University (Evanston, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Jiaxing Huang (Wilmette, Illinois);  Chenlong Cui (Guangdong, China PRC);  Alane Tarianna O. Lim (McLean, Virginia)
ABSTRACT Self-healing coating compositions are provided. In embodiments, such a composition comprises a liquid medium and a network of hollow capsules extending through the liquid medium in three dimensions, the network comprising a plurality of chains formed from the hollow capsules, aggregates of the hollow capsules, or both, wherein exterior surfaces of the hollow capsules of the plurality of chains define a plurality of channels filled with the liquid medium, and wherein the coating composition has a room temperature viscosity greater than that of the liquid medium. Coated surfaces formed from the compositions and methods of protecting surfaces using the compositions are also provided.
FILED Friday, January 03, 2020
APPL NO 17/419522
ART UNIT 1787 — Miscellaneous Articles, Stock Material
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 32/184 (20170801)

Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds
C01P 2004/30 (20130101)

Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General
C23C 26/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123465 Bourque et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Contracting Command (ACC)
Redstone Arsenal (REDSTONE)
APPLICANT(S) LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
ASSIGNEE(S) LOCKHEED MARTIN CORPORATION (Bethesda, Maryland)
INVENTOR(S) Richard T. Bourque (Oxford, Connecticut);  Erik M. Byrne (Stratford, Connecticut)
ABSTRACT A bushing assembly for a structure having a first aperture is provided. The bushing assembly includes a first component configured to be received by the first aperture and having a second aperture. A maximum width of the first component defines an outer diameter. The bushing assembly further includes a second component positioned outside of the first aperture and coupled to the first component, the second component having a third aperture extending through the second component. The third aperture is dimensioned so as to be equivalent to the outer diameter of the first component, and the first component and the second component are formed as discrete components of the bushing assembly.
FILED Friday, October 22, 2021
APPL NO 17/507958
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings
F16C 17/02 (20130101)
F16C 35/02 (20130101)
F16C 43/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123470 Baur et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Jeffery Baur (Liberty Township, Ohio);  David Seifert (Beavercreek, Ohio);  Geoffrey Frank (Dayton, Ohio);  Patrick Walgren (Anchorage, Alaska);  Darren Hartl (College Station, Ohio);  Wesley Chapkin (Fairborn, Ohio)
ABSTRACT A flexible multi-material structure comprises a spring skeleton comprising a plurality of repeating cells, the cells filled with an infill material, wherein the spring skeleton is one of a machined spring structure and a wave spring structure. The spring skeleton may comprise one of steel and polycarbonate blends, and the infill material may consist of one or more of foamed and monolithic elastomers. The foamed and monolithic elastomers consist of one or more of silicones, polyether, and polyurethane. The Poisson ratio of the infill material is about 0.1 to 0.3. The repeating cells of the spring skeleton have a predetermined wall thickness (t), wall height (h), and revolution symmetry.
FILED Monday, July 12, 2021
APPL NO 17/373101
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Springs; Shock-absorbers; Means for Damping Vibration
F16F 1/3605 (20130101) Original (OR) Class
F16F 2224/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123659 Keolian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Robert M. Keolian (State College, Pennsylvania);  Kevin J. Bastyr (Franklin, Michigan);  Ray Scott Wakeland (Marlborough, Massachusetts);  John Feurman Brady (Madison, Alabama)
ABSTRACT A heat exchanger with a monocoque structure transfers heat between a first fluid and a second fluid. The heat exchanger has a plurality of tubes through which the first fluid may flow in a direction, each of the plurality of tubes has a first mouth end, an opposing second mouth end and a waist region between the first mouth end and the second mouth end. The heat exchanger also has one or more intercom1ected fluid challllels through which the second fluid may flow. the one or more fluid chamlels lay generally in a plane, the plurality of tubes and the one or more fluid channels interleave such that heat may be transferred between the plurality of tubes and the one or more fluid challllels, and the direction of flow of the first fluid is generally perpendicular to the plane of the one or more fluid chamlels.
FILED Thursday, December 08, 2022
APPL NO 18/077939
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Hot Gas or Combustion-product Positive-displacement Engine Plants; Use of Waste Heat of Combustion Engines; Not Otherwise Provided for
F02G 1/055 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 7/163 (20130101) Original (OR) Class
F28D 2021/0026 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 1/025 (20130101)
F28F 1/44 (20130101)
F28F 13/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123670 Hoffman et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Brian Hoffman (Bloomington, Indiana);  Alex Smith (Long Valley, New Jersey);  Michael Colonnello (Mine Hill, New Jersey);  Eric Binter (Sussex, New Jersey)
ABSTRACT A remote weapon system (RWS) for an unmanned ground vehicle (UGV) includes a dedicated weapon, multi-axis gimbal and ammunition handling capabilities with all operations functioning remotely and wirelessly. The RWS comprises system-level and component-level safety features which preclude the weapon of the remote weapon system from being operable if removed from the remote weapon system.
FILED Friday, October 13, 2023
APPL NO 18/486303
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 7/06 (20130101)
F41A 9/34 (20130101)
F41A 9/37 (20130101)
F41A 17/42 (20130101)
F41A 19/08 (20130101) Original (OR) Class
F41A 19/12 (20130101)
F41A 19/58 (20130101)
F41A 25/00 (20130101)
F41A 25/14 (20130101)
F41A 27/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123672 Houck, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Thomas Klebert Houck, Jr. (Woodford, Virginia);  Matthew Thomas Buckler (Fredericksburg, Virginia);  Timothy Gerald Burcham (Fredericksburg, Virginia);  Kyle J. Campbell (Culpepper, Virginia);  Ryan G. Braughler (Alexandria, Virginia);  Yui Jean Clifford (Falmouth, Virginia);  Jonathan E. Scroggins (Fredericksburg, Virginia);  Zachary James Salvato (Fredericksburg, Virginia);  Steven James Walton (Mechanicsville, Virginia)
ASSIGNEE(S) United States of America, as represented by the Secretary of the Navy (Arlington, Virginia)
INVENTOR(S) Thomas Klebert Houck, Jr. (Woodford, Virginia);  Matthew Thomas Buckler (Fredericksburg, Virginia);  Timothy Gerald Burcham (Fredericksburg, Virginia);  Kyle J. Campbell (Culpepper, Virginia);  Ryan G. Braughler (Alexandria, Virginia);  Yui Jean Clifford (Falmouth, Virginia);  Jonathan E. Scroggins (Fredericksburg, Virginia);  Zachary James Salvato (Fredericksburg, Virginia);  Steven James Walton (Mechanicsville, Virginia)
ABSTRACT A rifle actuation mechanism is provided for alternately positioning a rifle between stowage within a cylindrical tube having a longitudinal axis and deployment for engaging a target. The mechanism includes a cradle, a yoke, and longitudinal, elevation and azimuth actuators. The cradle holds and fires the rifle. The yoke connects to the cradle. The longitudinal actuator translates the yoke along the axis. The elevation actuator pivots the cradle from the yoke. The azimuth actuator turns the cradle about the axis for pointing to the target. The tube contains the rifle, the cradle, the yoke and the actuators while in stowage. In preferred embodiments, the axis is substantially vertical.
FILED Tuesday, June 20, 2023
APPL NO 18/211779
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance
F41A 27/24 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123679 Kirk et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) John Kirk (Ashland, Massachusetts);  Richard D Landry (Worcester, Massachusetts)
ABSTRACT Apparatuses are disclosed herein for holding and securing an item. In one embodiment the item holder includes at least one layer of material between two outer layers of material. The two outer layers are made of a different material than the material of the at least one layer of material. Portions of the two outer layers and the at least one layer are secured together to form an opened ended receptacle for receiving an item. A set of hook/loop fasteners are secured to the exterior of the receptacle. The item holder also includes a material loop adapted to receive the receptacle. The material loop includes an interior surface that includes a second set of hook/loop fasters adapted to contact the first set of hook/loop fasteners. Although not required, an insertion tool may be used for insertion of receptacle into the material loop.
FILED Friday, July 22, 2022
APPL NO 17/870966
ART UNIT 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Travelling or Camp Equipment: Sacks or Packs Carried on the Body
A45F 5/021 (20130101)
A45F 2005/002 (20130101)
A45F 2005/025 (20130101)

Smallarms, e.g Pistols, Rifles; Accessories Therefor
F41C 33/045 (20130101)
F41C 33/0263 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123686 Coyle et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) David Coyle (Surprise, Arizona);  Daniel Treece (Buckeye, Arizona);  Wylie Standage-Beier (Phoenix, Arizona)
ABSTRACT A threat emitter system comprising a threat emitter comprising a main power supply, an external power source, a first sequencer, a driver amp, a second sequencer, a main amp, and a radio; a three-way power supply; a mixer, synthesizer, pre-amp, and cooling fans receiving electrical power from the three-way power supply; and an antenna in communication with the main amp; a user interface in communication with radio; the radio in communication with the mixer; the mixer in communication with the synthesizer; a filter in communication between the mixer and the pre-amp; the driver amp in communication with the pre-amp; the first sequencer in communication with the driver amp; the driver amp in communication with the main amp; a second sequencer in communication with the main amp; and a processor with access to a memory storing instructions executable by the processor.
FILED Thursday, March 03, 2022
APPL NO 17/653294
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 50/14 (20130101)
B60W 2540/215 (20200201)

Targets; Target Ranges; Bullet Catchers
F41J 2/00 (20130101) Original (OR) Class

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 9/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123881 Wandinger-Ness et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) UNM Rainforest Innovations (Albuquerque, New Mexico)
ASSIGNEE(S) UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico)
INVENTOR(S) Angela Wandinger-Ness (Albuquerque, New Mexico);  Tione Buranda (Albuquerque, New Mexico);  Peter Simons (Albuquerque, New Mexico);  Stephen Young (Albuquerque, New Mexico)
ABSTRACT The present invention is directed to the discovery that RapI-GTP, Rac1-GTP and Flt3-L can be used as Biomarkers for the early detection of sepsis in patients suspected of a bacterial infection which presents as sepsis or is likely to produce sepsis. In particular, the present invention is directed to methods, assays and kits which may be used to distinguish sepsis (infection) from systematic inflammatory response caused by sterile inflammation in trauma patients. The method may be used to diagnose bacteria infection and/or sepsis and monitor therapy of a patient to allow modification of treatment and/or cessation of treatment.
FILED Thursday, April 18, 2019
APPL NO 17/048941
ART UNIT 1678 — Fluid Handling and Dispensing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/14 (20130101)
G01N 33/563 (20130101)
G01N 33/588 (20130101)
G01N 33/6893 (20130101) Original (OR) Class
G01N 2800/26 (20130101)
G01N 2800/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123947 Reynolds et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Atmospheric and Space Technology Research Associates LLC (Louisville, Colorado)
ASSIGNEE(S) Atmospheric and Space Technology Research Associates LLC (Louisville, Colorado)
INVENTOR(S) Adam Scott Reynolds (Broomfield, Colorado);  Syed Mohammed Irfan Azeem (Louisville, Colorado);  Geoffrey Crowley (Lafayette, Colorado)
ABSTRACT A method of calculating ionospheric scintillation includes calculating a motion-corrected perturbation of a GNSS radio signal received by a monitoring device deployed in an oceanic environment. The method includes calculating the σΦ using the high rate phase of the GNSS signal adjusted by removing the change in distance between the monitoring device and the GNSS satellite. The calculating the σΦ may further include passing the adjusted high rate phase through a high pass filter to remove a drift motion of the monitoring device. The method further includes calculating the S4 through calculating a tilt angle between the antenna of the monitoring device with the GNSS satellite and adjusting the antenna gain through known gain pattern of the antenna. The wave height of the oceanic environment may be calculated by detrending the antenna height to remove low frequency motion when a high rate position of the monitoring device is calculated.
FILED Monday, March 08, 2021
APPL NO 17/194502
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 13/74 (20130101)
G01S 13/955 (20130101) Original (OR) Class
G01S 19/14 (20130101)
G01S 19/40 (20130101)
G01S 19/43 (20130101)
G01S 19/47 (20130101)
G01S 19/072 (20190801)

Meteorology
G01W 1/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123951 DeWeert et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) BAE SYSTEMS INFORMATION AND ELECTRONIC SYSTEMS INTEGRATION INC. (Nashua, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Michael J. DeWeert (Kaneohe, Hawaii);  Eric M. Louchard (Miami, Florida);  Reid A. Noguchi (Honolulu, Hawaii);  Gary Sawai (Wahiawa, Hawaii);  Dugan C. Yoon (Honolulu, Hawaii)
ABSTRACT A system and method is provided to characterize optical properties (Scattering, attenuation, de-polarization) of a light-transmitting medium and local environment, by determining a scattering rate of light through a medium, wherein determining the scattering rate of light through the medium is accomplished by utilizing polarized light transmitted from an optical source. The system and method performs a function based on the characterized optical properties of the medium, wherein the function is one of, for example: detection of objects embedded in the medium, object ranging through the medium, or deblurring of images acquired through the medium.
FILED Friday, April 29, 2022
APPL NO 17/733227
ART UNIT 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 4/04 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/4861 (20130101)
G01S 17/89 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 5/73 (20240101)
G06T 2207/20201 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12124097 Phillips et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island);  Nautilus Defense LLC (Pawtucket, Rhode Island)
ASSIGNEE(S) University of Rhode Island Board of Trustees (Kingston, Rhode Island);  Nautilus Defense LLC (Pawtucket, Rhode Island)
INVENTOR(S) Brennan T. Phillips (Wakefield, Rhode Island);  James B. Owens, Jr. (Lincoln, Rhode Island)
ABSTRACT Systems and methods for tethering a fiber optic cable to an apparatus such as an unmanned underwater vehicle (UUV) or remotely operated vehicle (ROV). The cable is a bare or tight-buffered optical fiber surrounded by a braided sheath, and is constructed so that loads experienced by the cable are not transferred from the sheath to the optical fiber. This construction enables the cable to have good tensile strength but be sufficiently lightweight so that a commercial fishing reel or any similarly scaled lightweight/portable winch system can be used, instead of large specialized deployment equipment. A tube is inserted between the sheath and the optical fiber a certain distance from the end of the cable, and then the cable and tube are inserted into a housing which attaches to the apparatus and potted using an epoxy resin.
FILED Tuesday, February 22, 2022
APPL NO 17/677651
ART UNIT 2874 — Optics
CURRENT CPC
Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Optical Elements, Systems, or Apparatus
G02B 6/3816 (20130101)
G02B 6/4427 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12124771 Reinhart et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Siemens Industry Software Inc. (Plano, Texas)
ASSIGNEE(S) Siemens Industry Software Inc. (Plano, Texas)
INVENTOR(S) Wesley Reinhart (Plainsboro, New Jersey);  Lucia Mirabella (Plainsboro, New Jersey);  Suraj Ravi Musuvathy (Princeton Junction, New Jersey)
ABSTRACT Methods and systems are disclosed for generation of cellular lattice kernels optimized by multiple objectives for highly specific targeted properties of geometry and topology rather than state of the art methods that rely on a predefined kernel library. Using a characterization of virtual kernel features, bulk material properties can be predicted using approximations from the virtual kernel rather than having to rely solely on experimental finite element simulations of lattice structures.
FILED Friday, September 06, 2019
APPL NO 17/273869
ART UNIT 2147 — Selective Visual Display Systems
CURRENT CPC
Electric Digital Data Processing
G06F 30/10 (20200101) Original (OR) Class
G06F 30/27 (20200101)

Computer Systems Based on Specific Computational Models
G06N 3/126 (20130101)
G06N 5/01 (20230101)
G06N 5/04 (20130101)
G06N 20/20 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12124784 Calisch et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Samuel E. Calisch (Cambridge, Massachusetts);  Neil A. Gershenfeld (Cambridge, Massachusetts)
ABSTRACT A method of producing inductive sensors, including LVDTs and inductive encoders, manufactured by plotting fine wire onto a planar substrate. A sensor is constructed using a computer-controlled machine to place wire onto a planar adhesive substrate. This substrate forms a predictable and uniform surface to deposit each turn of wire, and so the placement accuracy is considerably better than conventional coil winding. This planar substrate can then be manipulated into a desired three-dimensional shape (e.g., by folding, rolling, corrugating, winding, etc.), carrying the wire along with it. In particular, the same CNC machine used to place the wire can be used to cut, crease, score, or otherwise pattern the substrate to facilitate the three-dimensional arrangement.
FILED Tuesday, May 26, 2020
APPL NO 16/883434
ART UNIT 2851 — Printing/Measuring and Testing
CURRENT CPC
Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for
G01D 5/2291 (20130101)

Electric Digital Data Processing
G06F 30/392 (20200101) Original (OR) Class

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 41/086 (20160101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12125213 Mathai et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Army Medical Research Acquisition Activity (USAMRAA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
APPLICANT(S) Carnegie Mellon University (Pittsburgh, Pennsylvania);  University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
ASSIGNEE(S) Carnegie Mellon University (Pittsburgh, Pennsylvania);  University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania)
INVENTOR(S) Tejas Sudharshan Mathai (Seattle, Washington);  John Galeotti (Pittsburgh, Pennsylvania);  Vijay Saradhi Gorantla (Winston Salem, North Carolina)
ABSTRACT Provided is a system, method, and computer program product for segmenting vessels in an ultrasound image. The method includes detecting edges of a vessel in the ultrasound image; detecting a vessel contour of the vessel in the ultrasound image based on the detected edges and a distance regularized level set evolution; and tracking the vessel contour with a Kalman Filter.
FILED Friday, June 12, 2020
APPL NO 17/618151
ART UNIT 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 6/504 (20130101)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 7/12 (20170101)
G06T 7/149 (20170101) Original (OR) Class
G06T 2207/10081 (20130101)
G06T 2207/30101 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 30/40 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12125593 Sajda et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Paul Sajda (New York, New York);  Xueqing Liu (New York, New York)
ABSTRACT The present subject matter relates to techniques for hierarchical deep transcoding. The disclosed system can include a processor that can be configured to receive a functional magnetic resonance imaging (fMRI) data and/or an extracranial electroencephalogram (EEG) data and reconstruct a latent source space from the fMRI data and/or the EEG data by decoding the EEG data and/or the fMRI data to a latent source space. The fMRI data and the EEG data can be simultaneously acquired.
FILED Tuesday, October 05, 2021
APPL NO 17/494562
ART UNIT 2682 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 9/002 (20130101)
G06T 2207/10088 (20130101)

Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data
G16H 50/20 (20180101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12125693 Cooks
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Robert Graham Cooks (West Lafayette, Indiana)
ABSTRACT The invention generally relates to systems and methods for conducting reactions and screening for reaction products.
FILED Tuesday, October 10, 2023
APPL NO 18/378247
ART UNIT 2881 — Optics
CURRENT CPC
Electric Discharge Tubes or Discharge Lamps
H01J 49/0013 (20130101)
H01J 49/165 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12126152 Donatelli et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
APPLICANT(S) APG Vision LLC (Allison Park, Pennsylvania)
ASSIGNEE(S) APG VISION LLC (Allison Park, Pennsylvania)
INVENTOR(S) Gregory M. Donatelli (Hatboro, Pennsylvania);  Christopher C. McGeary (Gibsonia, Pennsylvania);  David M. McMeekin (Butler, Pennsylvania);  Tyler William Dulaney (Greenville, Pennsylvania)
ABSTRACT A ball mount assembly comprising a ball mount including a body having an opening and a base, the ball mount having an internal passage extending through the opening of the body in an axial direction of the ball mount; a compression fitting secured to the ball mount; and a sealing insert disposed in the internal passage of the ball mount, wherein the sealing insert is interposed between the compression fitting and the ball mount in the internal passage, and wherein the internal passage of the ball mount is defined by a first sidewall and a second sidewall.
FILED Tuesday, April 26, 2022
APPL NO 17/729513
ART UNIT 3631 — Static Structures, Supports and Furniture
CURRENT CPC
Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General
F16L 3/16 (20130101)

Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines
H02G 15/013 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12126295 Wheless
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Keyport, Washington)
INVENTOR(S) Jonathan Wheless (Bremerton, Washington)
ABSTRACT An apparatus and method for rotating a part includes a sequence of relays to rotate the part given number of degrees. The apparatus does not require software or complex mechanical gearing.
FILED Monday, September 18, 2023
APPL NO 18/369811
ART UNIT 2846 — Electrical Circuits and Systems
CURRENT CPC
Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils
H02P 3/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12126303 Liu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Luqiao Liu (Brookline, Massachusetts);  Justin Hou (Cambridge, Massachusetts);  Pengxiang Zhang (Cambridge, Massachusetts)
ABSTRACT An oscillator comprising, a cavity wherein the cavity comprises an electrical conductor. The oscillator comprising an electrical insulator disposed on a surface of the cavity; and a heterostructure disposed on a surface of the electrical insulator and having a first end and a second end, the heterostructure comprising one or more spin current source layers and one or more magnetic material layers. In response to an electrical current passed through the spin current source, an oscillation occurs in a plurality of magnetic domains of the magnetic material, wherein the oscillations have substantially the same phase.
FILED Friday, March 31, 2023
APPL NO 18/193885
ART UNIT 2849 — Electrical Circuits and Systems
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 10/329 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 1/02 (20130101)

Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 15/006 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12126740 Cambou et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona);  Government of the United States of America, as represented by the Secretary of the Air Force (Rome, New York)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona);  GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Rome, New York)
INVENTOR(S) Bertrand F. Cambou (Flagstaff, Arizona);  Sareh Assiri (Flagstaff, Arizona);  Christopher Robert Philabaum (Flagstaff, Arizona);  H. Shelton Jacinto (Rome, New York)
ABSTRACT Systems and methods for providing authentication and secure cryptographic communication between a client and server are described. The client includes an addressable array of PUF devices. The client receives or generates a set of instructions usable to determine a range of PUF addresses. The client measures the PUF addresses and generates a first set of responses. The responses are used to encrypt a session key, which is stored, along with the instructions and a hash of the responses, at the client. Later, the client may recover the session key by using the instructions to measure the PUF again, resulting in a second set of responses. Using a response-based cryptography search engine, the client may then iteratively modify and hash the second set of responses until a response set is uncovered that matches the first response set. This modified response set may then be used to uncover the session key.
FILED Saturday, June 25, 2022
APPL NO 17/849623
ART UNIT 2497 — Cryptography and Security
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 9/14 (20130101)
H04L 9/0822 (20130101)
H04L 9/0894 (20130101)
H04L 9/3236 (20130101)
H04L 9/3278 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12127006 D'Oro et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Salvatore D'Oro (Allston, Massachusetts);  Tommaso Melodia (Newton, Massachusetts);  Francesco Restuccia (Boston, Massachusetts);  Leonardo Bonati (Boston, Massachusetts)
ABSTRACT Methods and systems are provided for allocating resources to users in a wireless network including a plurality of edge nodes that provide wireless network access and multi-access edge computing functions. Slice requests are received from the users for a type of resource, including one or more of networking resources, storage resources, and computation resources. A set of slice requests to be admitted is determined based on resource availability constraints among one or more of the networking resources, the storage resources, and the computation resources at each edge node.
FILED Thursday, July 01, 2021
APPL NO 17/365070
ART UNIT 2641 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Wireless Communication Networks
H04W 4/021 (20130101)
H04W 16/10 (20130101) Original (OR) Class
H04W 16/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12127059 Melodia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Tommaso Melodia (Newton, Massachusetts);  Salvatore D'Oro (Allston, Massachusetts);  Michele Polese (Boston, Massachusetts);  Leonardo Bonati (Boston, Massachusetts)
ABSTRACT A radio access network (RAN) intelligent controller (RIC) and corresponding method may be implemented within RAN and in next-generation cellular networks to improve performance. The RIC comprises an interface to a RAN and further comprises a data-driven logic unit. The data-driven logic unit (i) produces, based on data received from the RAN via the interface, a representation describing a state of the RAN and (ii) based on the representation describing the state, instructs an action associated with at least one network element. The interface transmits a message based on the action instructed. The message is to be routed to the at least one network element. The representation is based on a context of the RAN. The message transmitted enabling re-configuration of the at least one network element. The re-configuration improves performance of the at least one network element within the context.
FILED Tuesday, November 23, 2021
APPL NO 17/456361
ART UNIT 2473 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 17/336 (20150115)

Wireless Communication Networks
H04W 28/24 (20130101)
H04W 28/0236 (20130101)
H04W 28/0967 (20200501)
H04W 36/06 (20130101) Original (OR) Class
H04W 36/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 12121846 Elliott et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) ExxonMobil Technology and Engineering Company (Annandale, New Jersey);  TDA Research, Inc. (Wheat Ridge, Colorado)
ASSIGNEE(S) ExxonMobil Technology and Engineering Company (Annandale, Virginia);  TDA Research, Inc. (Wheat Ridge, Colorado)
INVENTOR(S) Jeannine Elizabeth Elliott (Superior, Colorado);  Robert James Copeland (Arvada, Colorado);  Jeff Lind (Arvada, Colorado);  Daniel P. Leta (Flemington, New Jersey);  Patrick P. McCall (Matawan, New Jersey)
ABSTRACT A system and method for separating and/or purification of CO2 gas from a CO2 feed stream is described. The system and method include a plurality of fixed sorbent beds, adsorption zones and desorption zones, where the sorbent beds are connected via valve and lines to create a simulated moving bed system, where the sorbent beds move from one adsorption position to another adsorption position, and then into one regeneration position to another regeneration position, and optionally back to an adsorption position. The system and method operate by concentration swing adsorption/desorption and by adsorptive/desorptive displacement.
FILED Monday, September 28, 2020
APPL NO 17/034283
ART UNIT 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 53/06 (20130101)
B01D 53/10 (20130101)
B01D 53/0446 (20130101) Original (OR) Class
B01D 2253/104 (20130101)
B01D 2257/504 (20130101)
B01D 2258/0283 (20130101)
B01D 2259/402 (20130101)
B01D 2259/4009 (20130101)
B01D 2259/4065 (20130101)
B01D 2259/4067 (20130101)
B01D 2259/40003 (20130101)
B01D 2259/40086 (20130101)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 20/40 (20200801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121850 Sigfússon et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) Carbfix (Reykjavik, Iceland);  UNIVERSITY OF ICELAND (Reykjavik, Iceland);  THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York);  BARNARD COLLEGE (New York, New York)
ASSIGNEE(S) Carbfix (Reykjavik, Iceland)
INVENTOR(S) Bergur Sigfússon (Reykjavik, Iceland);  Edda Sif Pind Aradóttir (Reykjavik, Iceland);  Ingvi Gunnarsson (Reykjavik, Iceland);  Magnus pór Arnarson (Reykjavik, Iceland);  Einar Gunnlaugsson (Reykjavik, Iceland);  Hólmfriður Sigurdardóttir (Reykjavik, Iceland);  Húni Sighvatsson (Reykjavik, Iceland);  Sigurður Reynir Gíslason (Reykjavik, Iceland);  Eric H. Oelkers (Toulouse, France);  Kiflom G. Mesfin (Reykjanesbrer, Iceland);  Sandra Ósk Snæbjörnsdóttir (Reykjavik, Iceland);  Iwona M. Galeczka (Kopavogur, Iceland);  Domenik Wolff-Boenisch (Coolbellup, Australia);  Helgi A. Alfredsson (Myvatni, Iceland);  Porsteinn Jónsson (Reykjavik, Iceland);  Andri Stefánsson (Reykjavik, Iceland);  Jürg Matter (Winchester, United Kingdom);  Martin Stute (New York, New York);  Deirdre Elizabeth Clark (Reykjavik, Iceland);  Martin Johannes Voigt (Sturlugata, Iceland)
ABSTRACT This invention relates to a method and a system of abating carbon dioxide (CO2) and/or hydrogen sulfide (H2S) in a geological reservoir. Water is pumped or transferred from a water source to an injection well. The gasses are merged with the water under conditions where the hydraulic pressure of the water is less than the pressure of CO2 and/or H2S gas at the merging point. The water with CO2 and/or H2S gas bubbles is transferred further downwardly at a certain velocity higher than the upward flow velocity of said CO2 and/or H2S gas bubbles ensuring downward movement of gas bubbles resulting in full dissolution of said CO2 and/or H2S in the water due to elevating pressure. The complete dissolution ensures a lowered pH of the water entering a geological (e.g. geothermal) reservoir which is needed to promote mineral reactions leading to CO2 and H2S abatement This abatement may be quantified by dissolving a tracer substance in a predetermined molar ratio to said dissolved CO2 and/or H2S and monitored in a monitoring well.
FILED Friday, May 22, 2020
APPL NO 17/595572
ART UNIT 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Separation
B01D 53/1412 (20130101)
B01D 53/1468 (20130101)
B01D 53/1475 (20130101) Original (OR) Class
B01D 2252/103 (20130101)

Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors
B65G 5/00 (20130101)

Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 41/0064 (20130101)
E21B 47/11 (20200501)

Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG]
Y02C 20/40 (20200801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121878 Knipe et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Jennifer Marie Knipe (Oakland, California);  Sarah E. Baker (Dublin, California);  Maira Ceron Hernandez (Brentwood, California);  Jeremy M. Lenhardt (Tracy, California);  Simon Hoching Pang (Fremont, California);  Joshuah K. Stolaroff (Oakland, California);  Matthew A. Worthington (Oakland, California)
ABSTRACT An ink includes a vinyl-terminated polydimethylsiloxane polymer, a polydimethylsiloxane copolymer having a hydride component, wherein a hydride to a vinyl ratio (hydride:vinyl) is in a range of greater than 1:1 to about 4:1, a hydrophobic filler, a crosslinking agent, and a carbon dioxide-binding component. A method includes extruding an ink for forming a three-dimensional (3D) structure, the ink including a vinyl-terminated polydimethylsiloxane polymer, a polydimethylsiloxane copolymer having a hydride component, wherein a hydride to a vinyl ratio (hydride:vinyl) is in a range of greater than 1:1 to about 4:1, a hydrophobic filler, a crosslinking agent, and a carbon dioxide-binding component. The method further includes curing the 3D structure for forming a silicone polymer product having the carbon dioxide-binding component.
FILED Monday, October 18, 2021
APPL NO 17/504336
ART UNIT 1763 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/267 (20130101) Original (OR) Class
B01J 20/28042 (20130101)
B01J 2220/46 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/118 (20170801)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2083/00 (20130101)
B29K 2509/02 (20130101)
B29K 2995/0093 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)

Compositions of Macromolecular Compounds
C08L 83/04 (20130101)
C08L 2205/02 (20130101)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 7/61 (20180101)
C09D 7/69 (20180101)
C09D 183/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122065 Bradshaw et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) InventWood Inc. (College Park, Maryland)
ASSIGNEE(S) InventWood Inc. (College Park, Maryland)
INVENTOR(S) Allan Bradshaw (Seattle, Washington);  Jack G. Winterowd (Puyallup, Washington)
ABSTRACT This disclosure is directed to methods of separating wood veneer material by property measurements, and thereafter improving the properties of veneer material with property values lower than a target threshold value, until those materials meet or exceed that threshold values. In some aspects of the disclosure, veneer materials are prepared, non-destructively measured, and separated into passing and failing material collections. The failing material collection may then be treated to improve the density and flexural modulus of the material therein. Also disclosed herein are products and materials incorporating the treated veneer materials according to the disclosed methods.
FILED Thursday, September 14, 2023
APPL NO 18/368472
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Working Veneer or Plywood
B27D 3/00 (20130101)

Processes, Apparatus or Selection of Substances for Impregnating, Staining, Dyeing, Bleaching of Wood or Similar Materials, or Treating of Wood or Similar Materials With Permeant Liquids, Not Otherwise Provided for; Chemical or Physical Treatment of Cork, Cane, Reed, Straw or Similar Materials
B27K 3/18 (20130101)
B27K 3/025 (20130101) Original (OR) Class
B27K 3/42 (20130101)
B27K 2200/30 (20130101)
B27K 2240/70 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122376 Tang et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Delphi Technologies IP Limited (St. Michael, Barbados)
ASSIGNEE(S) Delphi Technologies IP Limited (Saint Michael, Barbados)
INVENTOR(S) Li Tang (Troy, Michigan);  Neeraj Rama (Rochester Hills, Michigan);  Peter Michael Olin (Ann Arbor, Michigan)
ABSTRACT A method for controlling vehicle propulsion may include identifying at least one route characteristic of a portion of a route being traversed by a vehicle and determining a profile for a target vehicle speed based on the at least one route characteristic and a vehicle energy consumption profile. The method may also include, in response to detecting a lead vehicle, determining a vehicle speed of the lead vehicle and determining whether to avoid triggering initiation of the vehicle follow mode by the vehicle propulsion controller based on (i) a distance between the vehicle and a triggering threshold and (ii) the vehicle speed of the vehicle. The method may also include, in response to not triggering vehicle follow mode, determining, based on the vehicle speed of the lead vehicle and the profile for the target vehicle speed, a traveling distance between the vehicle and a trigger threshold.
FILED Wednesday, August 10, 2022
APPL NO 17/885050
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 30/143 (20130101) Original (OR) Class
B60W 40/105 (20130101)
B60W 2554/80 (20200201)
B60W 2556/10 (20200201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122668 Black et al.
FUNDED BY
Department of Energy (DOE)
Brookhaven Science Associates, LLC (BSA)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S) Brookhaven Science Associates, LLC (Upton, New York)
ASSIGNEE(S) Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S) Charles T. Black (New York, New York);  Atikur Rahman (Ridge, New York);  Matthew Eisaman (Port Jefferson, New York);  Ahsan Ashraf (Port Jefferson, New York)
ABSTRACT Methods for etching nanostructures in a substrate include depositing a patterned block copolymer on the substrate, the patterned block copolymer including first and second polymer block domains, applying a precursor to the patterned block copolymer to generate an infiltrated block copolymer, the precursor infiltrating into the first polymer block domain and generating a material in the first polymer block domain, applying a removal agent to the infiltrated block copolymer to generate a patterned material, the removal agent removing the first and second polymer block domains from the substrate, and etching the substrate, the patterned material on the substrate masking the substrate to pattern the etching. The etching may be performed under conditions to produce nanostructures in the substrate.
FILED Wednesday, July 06, 2022
APPL NO 17/858855
ART UNIT 2872 — Optics
CURRENT CPC
Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 1/00031 (20130101) Original (OR) Class
B81C 1/00111 (20130101)
B81C 2201/0132 (20130101)
B81C 2201/0149 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/118 (20130101)

Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor;
G03F 7/0002 (20130101)
G03F 7/405 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 2237/334 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/0271 (20130101)
H01L 21/0273 (20130101)
H01L 21/0337 (20130101)
H01L 21/3065 (20130101)
H01L 21/3086 (20130101)
H01L 31/02363 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122797 Hartmann-Thompson et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) 3M INNOVATIVE PROPERTIES COMPANY (St. Paul, Minnesota)
ASSIGNEE(S) 3M Innovative Properties Company (St. Paul, Minnesota)
INVENTOR(S) Claire Hartmann-Thompson (Lake Elmo, Minnesota);  Marina M. Kaplun (Woodbury, Minnesota)
ABSTRACT A dihaloorganosilane is represented by the formula (I): Each X independently represents Cl, Br, or I. Each Ar1 independently represents a phenylene group optionally substituted by 1 to 4 alkyl groups selected from methyl or ethyl. Each R1 independently represents an alkylene group having from 2 to 18 carbon atoms. Each R2 independently represents methyl or ethyl. Each R3 independently represents an alkylene group having from 1 to 18 carbon atoms. Each R4 independently represents an alkylene group having from 2 to 18 carbon atoms, and n is an integer in a range of 0 to 5, inclusive. Ionic organosilanes preparable from the dihaloorganosilanes are represented by the formula (II): Membrane compositions and membranes containing the ionic organosilanes are also disclosed.
FILED Friday, June 12, 2020
APPL NO 17/612469
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 7/081 (20130101) Original (OR) Class

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 212/08 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 5/5406 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122962 Marker et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Gas Technology Institute (Des Plaines, Illinois)
ASSIGNEE(S) GTI Energy (Des Plaines, Illinois)
INVENTOR(S) Terry Marker (Palos Heights, Illinois);  Jim Wangerow (Oak Park, Illinois);  Pedro Ortiz-Toral (Wheeling, Illinois);  Martin Linck (Roscoe, Illinois)
ABSTRACT Processes and catalysts for producing hydrogen by reforming methane are disclosed, which afford considerable flexibility in terms of the quality of the reformer feed. This can be attributed to the robustness of the noble metal-containing catalysts described herein for use in reforming, such that a number of components commonly present in methane-containing process streams can advantageously be maintained without conventional upgrading (pretreating) steps, thereby improving process economics. This also allows for the reforming of impure reformer feeds, even in relatively small quantities, which may be characterized as complex gas mixtures due to significant quantities of non-methane components. A representative reforming catalyst comprises 1 wt-% Pt and 1 wt-% Rh as noble metals, on a cerium oxide support.
FILED Wednesday, July 17, 2019
APPL NO 16/514677
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 23/38 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 3/40 (20130101)
C01B 2203/0233 (20130101)
C01B 2203/0261 (20130101)
C01B 2203/1064 (20130101)

Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes
C10G 2/331 (20130101) Original (OR) Class
C10G 2300/1011 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122967 Siriwardane
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S) United States Department of Energy (Washington, District of Columbia)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Ranjani Siriwardane (Morgantown, West Virginia)
ABSTRACT Materials, methods to prepare, and methods of use for producing an H2 rich synthesis gas stream from coal free of nitrogen is described. One embodiment of the method comprises. The method includes an oxygen carrier at least partially reduced using a fuel in a reactor forming a reduced metal oxide comprised of first series—3d block-transition metals or mixture thereof. The reduced metal oxide is reacted with the solid fuel/steam to produce H2 and CO2/CO in the reactor; and the reduced metal oxide is added separately or simultaneously with a solid fuel while not impregnating the solid fuel with the reduced metal oxide.
FILED Monday, October 19, 2020
APPL NO 17/073648
ART UNIT 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases
C10J 3/10 (20130101) Original (OR) Class
C10J 3/16 (20130101)
C10J 3/725 (20130101)
C10J 2300/093 (20130101)
C10J 2300/0959 (20130101)
C10J 2300/0976 (20130101)
C10J 2300/1823 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123038 Ramakrishnan et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
Office of Science (DOE-SC)
Lawrence Berkeley National Laboratory (LBNL)
Federally Funded Research and Development Center (FFRDC)
Operated by University of California (UC BERKELEY) at Berkeley, CA
APPLICANT(S) National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico)
ASSIGNEE(S) NATIONAL TECHNOLOGY and ENGINEERING SOLUTIONS OF SANDIA, LLC (Albuquerque, New Mexico)
INVENTOR(S) Parthasarathi Ramakrishnan (Lucknow, India);  Jian Sun (Albany, California);  Tanmoy Dutta (Berkeley, California);  Blake A. Simmons (San Francisco, California);  Seema Singh (Clarksburg, Maryland)
ABSTRACT The present invention provides for novel protic ionic liquids (PIL) or phosphate-based ionic liquid (PBIL) useful for lignocellulosic processing described herein. The novel protic ionic liquids are capable of pretreatment of lignocellulosic biomass over a wide range of pH.
FILED Monday, February 25, 2019
APPL NO 16/284941
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 251/02 (20130101)

Compositions of Macromolecular Compounds
C08L 97/00 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/10 (20130101)
C12P 19/02 (20130101) Original (OR) Class
C12P 19/14 (20130101)
C12P 2201/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123045 Liao et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) CARGILL, INCORPORATED (Wayzata, Minnesota)
ASSIGNEE(S) CARGILL, INCORPORATED (Wayzata, Minnesota)
INVENTOR(S) Hans H. Liao (Plymouth, Minnesota);  Catherine Bradshaw Poor (Plymouth, Minnesota);  Travis Robert Wolter (Plymouth, Minnesota);  Michael Tai Man Louie (Plymouth, Minnesota);  Erin Kathleen Marasco (Plymouth, Minnesota);  Ana Negrete-Raymond (Ply', Minnesota)
ABSTRACT Genes encoding mutant 3-ketoacyl-CoA synthases are introduced into host cells. Certain of the mutants enhance the production of shorter-chain fatty acids and derivatives by the cell than do the wild-type (unmutated) enzymes. In other cases, the chain length is not significantly affected, but productivity is enhanced. In specific cases, both a shift toward lower chain length and higher productivity is seen. Cells producing the mutant 3-ketoacyl-CoA synthases are especially suitable for producing C6-C10 fatty acids and derivatives.
FILED Monday, May 02, 2022
APPL NO 17/661613
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 1/20 (20130101)
C12N 9/1029 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/6409 (20130101)
C12P 7/6436 (20130101) Original (OR) Class

Enzymes
C12Y 203/01199 (20150701)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123617 Bahar et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) FFI IONIX IP, INC. (Wilmington, Delaware)
ASSIGNEE(S)
INVENTOR(S) Bamdad Bahar (Georgetown, Delaware);  William Parmelee (Orleans, Massachusetts);  Omar Abdelaziz (Oak Ridge, Tennessee);  Qu Ming (Oak Ridge, Tennessee)
ABSTRACT A cooling system utilizes an organic ionic salt composition for dehumidification of an airflow. The organic ionic salt composition absorbs moisture from an inlet airflow to produce an outlet airflow with a reduce moisture from that of the inlet airflow. The organic ionic salt composition may be regenerated, wherein the absorbed moisture is expelled by heating with a heating device. The heating device may be an electrochemical heating device, such as a fuel cell, an electrochemical metal hydride heating device, an electrochemical heat pump or compressor, or a condenser of a refrigerant cycle, which may utilize an electrochemical pump or compressor. The efficiency of the cooling system may be increased by utilization of the waste heat the cooling system. The organic ionic salt composition may circulate back and forth or in a loop between a conditioner, where it absorbs moisture, to a regenerator, where moisture is desorbed by heating.
FILED Monday, August 07, 2023
APPL NO 18/231069
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Separation
B01D 1/14 (20130101)
B01D 5/0003 (20130101)
B01D 5/009 (20130101)
B01D 5/0027 (20130101)
B01D 5/0039 (20130101)
B01D 5/0087 (20130101)
B01D 53/263 (20130101)
B01D 53/268 (20130101)
B01D 2252/30 (20130101)

Heterocyclic Compounds
C07D 233/58 (20130101)

Compositions of Macromolecular Compounds
C08L 27/12 (20130101)

Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening
F24F 3/001 (20130101)
F24F 3/1417 (20130101) Original (OR) Class
F24F 2003/1458 (20130101)

Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems
F25B 17/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123655 Klausner et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) James F. Klausner (Point Roberts, Washington);  Joerg Petrasch (Dornbirn, Austria);  Kelvin Randhir (San Diego, California);  Nima Rahmatian (San Diego, California)
ABSTRACT Systems and methods for energy storage and energy recovery are provided. An electrical-to-electrical energy storage system includes a thermochemical energy storage device, a blower, a compressor, a turbine, and an electrical generator. The TCES device includes a vessel, a porous bed, and a heater. The porous bed is disposed within an interior volume of the vessel. The porous bed comprises a reactive material. The reactive material is configured to release oxygen upon being heated to a reduction temperature, and generate heat when exposed to oxygen. The heater is in thermal contact with the reactive material. The blower is configured to remove oxygen from the interior volume. The compressor is configured to flow oxygen into the interior volume. The turbine is configured to receive a heated, oxygen-depleted gas from the interior volume. The generator is configured to be powered by the turbine to generate electricity.
FILED Monday, August 28, 2023
APPL NO 18/238579
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 7/024 (20130101)
F28D 20/003 (20130101) Original (OR) Class
F28D 2020/0017 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123659 Keolian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Penn State Research Foundation (University Park, Pennsylvania)
ASSIGNEE(S) The Penn State Research Foundation (University Park, Pennsylvania)
INVENTOR(S) Robert M. Keolian (State College, Pennsylvania);  Kevin J. Bastyr (Franklin, Michigan);  Ray Scott Wakeland (Marlborough, Massachusetts);  John Feurman Brady (Madison, Alabama)
ABSTRACT A heat exchanger with a monocoque structure transfers heat between a first fluid and a second fluid. The heat exchanger has a plurality of tubes through which the first fluid may flow in a direction, each of the plurality of tubes has a first mouth end, an opposing second mouth end and a waist region between the first mouth end and the second mouth end. The heat exchanger also has one or more intercom1ected fluid challllels through which the second fluid may flow. the one or more fluid chamlels lay generally in a plane, the plurality of tubes and the one or more fluid channels interleave such that heat may be transferred between the plurality of tubes and the one or more fluid challllels, and the direction of flow of the first fluid is generally perpendicular to the plane of the one or more fluid chamlels.
FILED Thursday, December 08, 2022
APPL NO 18/077939
ART UNIT 3763 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Hot Gas or Combustion-product Positive-displacement Engine Plants; Use of Waste Heat of Combustion Engines; Not Otherwise Provided for
F02G 1/055 (20130101)

Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact
F28D 7/163 (20130101) Original (OR) Class
F28D 2021/0026 (20130101)

Details of Heat-exchange and Heat-transfer Apparatus, of General Application
F28F 1/025 (20130101)
F28F 1/44 (20130101)
F28F 13/003 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12124003 Kozodoy et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Glint Photonics, Inc. (Burlingame, California)
ASSIGNEE(S) Glint Photonics, Inc. (Burlingame, California)
INVENTOR(S) Peter Kozodoy (Palo Alto, California);  John Lloyd (San Mateo, California)
ABSTRACT Methods for forming optical articles with antireflective nanostructured (ARN) surfaces. An aluminum layer is deposited or otherwise applied to the cavity of an injection mold tool. Sequential chemical treatments such as anodization and etching steps form an ARN mold texture on the interior surface of the cavity. The ARN mold texture is a negative of a desired surface texture of the article. During injection molding, the desired ARN surface is thereby produced in the optical article.
FILED Tuesday, April 27, 2021
APPL NO 17/241151
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 33/3842 (20130101)
B29C 45/372 (20130101)
B29C 2033/385 (20130101)

Producing Particular Articles From Plastics or From Substances in a Plastic State
B29D 11/00192 (20130101)
B29D 11/00365 (20130101)
B29D 11/00375 (20130101)
B29D 11/00865 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2011/00 (20130101)

Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor
C25D 11/12 (20130101)
C25D 11/022 (20130101)
C25D 11/24 (20130101)

Optical Elements, Systems, or Apparatus
G02B 1/118 (20130101) Original (OR) Class
G02B 2207/101 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12124279 Paglieroni et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) David W. Paglieroni (Pleasanton, California);  N. Reginald Beer (Pleasanton, California);  David Chambers (Livermore, California)
ABSTRACT A system for determining optimal paths without collision through a travel volume for a swarm of vehicles is disclosed. The system determines a travel path for the swarm leader vehicle using a minimal cost path derived from various measures of environmental cost for avoiding objects in traveling from leader location to target location. The system also determines, for each empty neighbor location of each follower vehicle, relational costs for follower vehicle travel relative to leader vehicle travel. The various measures of relational cost seek to maintain a prescribed positional relationship between each follower vehicle and the leader vehicle given the leader vehicle travel path. Based on various measures of environmental and relational cost, the system determines the best travel path for the each follower vehicle relative to the leader vehicle.
FILED Wednesday, April 12, 2017
APPL NO 16/603816
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Unmanned aerial vehicles [UAV]; equipment therefor
B64U 2201/10 (20230101)
B64U 2201/102 (20230101)

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/3446 (20130101)
G01C 21/3453 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 1/0027 (20130101)
G05D 1/104 (20130101) Original (OR) Class
G05D 1/1064 (20190501)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/047 (20130101)

Traffic Control Systems
G08G 5/0021 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12124311 Bharadwaj
FUNDED BY
Department of Energy (DOE)
Exascale Computing Project (ECP)
PathForward Project (PATHFORWARD)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) ADVANCED MICRO DEVICES, INC. (Santa Clara, California)
ASSIGNEE(S) Advanced Micro Devices, Inc. (Santa Clara, California)
INVENTOR(S) Vedula Venkata Srikant Bharadwaj (Bellevue, Washington)
ABSTRACT A processing unit includes compute units partitioned into one or islands that are provided with operating voltages and clock signals having clock frequencies independent of providing operating voltages or clock signals to other islands of compute units. The processing unit also includes dynamic voltage and frequency scaling (DVFS) hardware configured to compute one or more numbers of active memory barriers in the one or more islands. The DVFS hardware is also configured to modify the operating voltages or clock frequencies provided to the one or more islands in response to a change in numbers of active memory barriers in the one or more islands. In some cases, the operating voltage or clock frequency provided to an island is increased in response to the number of active memory barriers in the island decreasing. The operating voltage or clock frequency provided to the island is decreased in response to the number of active memory barriers in the island increasing.
FILED Tuesday, November 23, 2021
APPL NO 17/533548
ART UNIT 2187 — Computer Architecture and I/O
CURRENT CPC
Electric Digital Data Processing
G06F 1/324 (20130101)
G06F 1/3225 (20130101) Original (OR) Class
G06F 1/3296 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12124582 Gourisetti et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Pacific Northwest National Laboratory (PNNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Memorial Institute (BMI) at Richland, WA
APPLICANT(S) Battelle Memorial Institute (Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Sri Nikhil Gupta Gourisetti (Richland, Washington);  Michael E. Mylrea (Alexandria, Virginia);  Md. Touhiduzzaman (Richland, Washington);  Travis Ashley (Richland, Washington);  Beverly E. Johnson (Richland, Washington);  Newton B. Brown (Richland, Washington);  Penny L. McKenzie (Richland, Washington);  Seemita Pal (Richland, Washington)
ABSTRACT Method include receiving banner information from one or more queries of a network connecting a set of devices, wherein the banner information of one or more of the devices includes common vulnerability and exposure identifiers (CVEs) and the banner information of one or more of the devices does not include a CVE, identifying the devices based on the banner information including classifying devices without known CVEs by a device type, determining vulnerability scores for the devices with known CVEs based on retrieved CVE information, and determining vulnerability scores for the devices without CVEs based on a series of exploitability and impact parameter estimates associated with the device type classifications. Some methods include estimating a cyberattack vulnerability risk for the devices using the determined vulnerability scores.
FILED Thursday, December 10, 2020
APPL NO 17/117752
ART UNIT 2491 — Cryptography and Security
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 19/058 (20130101)
G05B 2219/14006 (20130101)
G05B 2219/15012 (20130101)

Electric Digital Data Processing
G06F 16/285 (20190101)
G06F 16/953 (20190101)
G06F 21/577 (20130101) Original (OR) Class
G06F 2221/034 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12125967 Sakamoto et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) The Regents of The University of Michigan (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Jeffrey Sakamoto (Ann Arbor, Michigan);  Travis Thompson (Ann Arbor, Michigan);  Asma Sharafi (Ypsilanti, Michigan);  Nathan Taylor (Ann Arbor, Michigan);  Neil P. Dasgupta (Ann Arbor, Michigan);  Eric Kazyak (Ann Arbor, Michigan)
ABSTRACT A method is disclosed for suppressing propagation of a metal in a solid state electrolyte during cycling of an electrochemical device including the solid state electrolyte and an electrode comprising the metal. One method comprises forming the solid state electrolyte such that the solid state electrolyte has a structure comprising a plurality of grains of a metal-ion conductive material and a grain boundary phase located at some or all of grain boundaries between the grains, wherein the grain boundary phase suppresses propagation of the metal in the solid state electrolyte during cycling. Another method comprises forming the solid state electrolyte such that the solid state electrolyte is a single crystal.
FILED Wednesday, June 06, 2018
APPL NO 16/001407
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/382 (20130101)
H01M 4/525 (20130101)
H01M 4/5825 (20130101)
H01M 10/052 (20130101)
H01M 10/058 (20130101)
H01M 10/0525 (20130101)
H01M 10/0562 (20130101) Original (OR) Class
H01M 2300/0071 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12125979 Liu et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California)
INVENTOR(S) Ping Liu (San Diego, California);  Yejing Li (San Diego, California)
ABSTRACT A solid-state battery and process of forming the same is provided. The solid-state battery includes a first metal electrode. The solid-state battery includes a first mixed conductor disposed on the first metal electrode. The first mixed conductor includes a mixture of ionic and electronic conductors. The solid-state battery includes a pure ionic conductor disposed on the first mixed conductor. The solid-state battery includes a second metal electrode disposed on top of the pure ionic conductor.
FILED Wednesday, March 11, 2020
APPL NO 17/437778
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/134 (20130101)
H01M 10/0562 (20130101)
H01M 10/0565 (20130101) Original (OR) Class
H01M 50/414 (20210101)
H01M 50/434 (20210101)
H01M 50/449 (20210101)
H01M 50/497 (20210101)
H01M 2300/008 (20130101)
H01M 2300/0071 (20130101)
H01M 2300/0082 (20130101)
H01M 2300/0094 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12126243 Alahyari et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut)
ASSIGNEE(S) RTX CORPORATION (Farmington, Connecticut)
INVENTOR(S) Abbas A. Alahyari (Glastonbury, Connecticut);  Parag M. Kshirsagar (South Windsor, Connecticut)
ABSTRACT A cooling system for a superconducting electric machine may comprise a fluid reservoir and a first fluid comprising a first mixture of hydrogen and helium configured to be stored in the fluid reservoir. A plurality of conduits may be fluidly coupled to the fluid reservoir and may form a closed loop between the fluid reservoir and the superconducting electric machine.
FILED Friday, January 21, 2022
APPL NO 17/581572
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Dynamo-electric Machines
H02K 9/20 (20130101)
H02K 55/04 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12126374 Majid et al.
FUNDED BY
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
APPLICANT(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
ASSIGNEE(S) Battelle Energy Alliance, LLC (Idaho Falls, Idaho)
INVENTOR(S) Arslan J. Majid (Salt Lake City, Utah);  Hussein Moradi (Idaho Falls, Idaho);  Behrouz Farhang (Salt Lake City, Utah)
ABSTRACT Various embodiments relate to spread spectrum communication. A communication system may include a base station and a user equipment. The base station may be configured to: add a cyclic prefix (CP) to each block of a number of blocks of a first direct sequence spread spectrum (DSSS) signal to generate a first cyclic prefix-direct sequence spread spectrum (CP-DSSS) signal; add artificial noise to the first CP-DSSS signal; and transmit, via a channel, the first CP-DSSS signal. The user equipment is configured to receive the first CP-DSSS signal. Associated methods and communications systems are also disclosed.
FILED Monday, December 20, 2021
APPL NO 17/645220
ART UNIT 2633 — Digital Communications
CURRENT CPC
Transmission
H04B 1/7097 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12127324 Shumlak et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) ZAP ENERGY, INC. (Seattle, Washington)
ASSIGNEE(S) Zap Energy, Inc. (Everett, Washington)
INVENTOR(S) Uri Shumlak (Seattle, Washington);  Brian A. Nelson (Edmonds, Washington);  Eric T. Meier (Seattle, Washington)
ABSTRACT Methods and systems are provided for plasma confinement utilizing various electrode and valve configurations. In one example, a device includes a first electrode positioned to define an outer boundary of an acceleration volume, a second electrode arranged coaxially with respect to the first electrode and positioned to define an inner boundary of the acceleration volume, at least one power supply to drive an electric current along a Z-pinch plasma column between the first second electrodes, and a set of valves to provide gas to the acceleration volume to fuel the Z-pinch plasma column, wherein an electron flow of the electric current is in a first direction from the second electrode to the first electrode. In additional or alternative examples, a shaping part is conductively connected to the second electrode to, in a presence of the gas, cause a gas breakdown of the gas to generate a sheared flow velocity profile.
FILED Friday, May 27, 2022
APPL NO 17/827379
ART UNIT 2844 — Electrical Circuits and Systems
CURRENT CPC
Fusion Reactors
G21B 1/05 (20130101)
G21B 1/21 (20130101)

Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams
H05H 1/06 (20130101) Original (OR) Class
H05H 1/54 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 12121094 Lu
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical, Bioengineering, Environmental and Transport Systems (CBET)
APPLICANT(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Weiyi Lu (Middleton, Wisconsin)
ABSTRACT An energy absorbing apparatus includes particles with nanopores in a liquid. A further aspect employs a reusable energy absorbing apparatus including gas-liquid interactions in nanopores. Another aspect of the present apparatus uses oversolubility of gas in a solution to enhance bubble nucleation in hydrophobic nanopores or nanochannels, which suppresses gas outflow while promoting liquid outflow from particles. Still another aspect includes anions within an aqueous electrolytic solution, containing nanoporous material therein.
FILED Tuesday, October 12, 2021
APPL NO 17/498952
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Hats; Head Coverings
A42B 3/121 (20130101) Original (OR) Class

Springs; Shock-absorbers; Means for Damping Vibration
F16F 9/006 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121339 Gharagouzloo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Science Foundation (NSF)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Codi Gharagouzloo (Medford, Massachusetts);  Srinivas Sridhar (Newton, Massachusetts)
ABSTRACT A quantitative, ultrashort time to echo, contrast-enhanced magnetic resonance imaging technique is provided. The technique can be used to accurately measure contrast agent concentration in the blood, to provide clear, high-definition angiograms, and to measure absolute quantities of cerebral blood volume on a voxel-by-voxel basis.
FILED Thursday, June 09, 2016
APPL NO 15/747202
ART UNIT 3798 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/055 (20130101) Original (OR) Class
A61B 5/425 (20130101)
A61B 5/4064 (20130101)
A61B 5/4088 (20130101)
A61B 5/4244 (20130101)
A61B 5/4866 (20130101)
A61B 2576/026 (20130101)

Measuring Electric Variables; Measuring Magnetic Variables
G01R 33/4816 (20130101)
G01R 33/5601 (20130101)
G01R 33/5635 (20130101)
G01R 33/56366 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121366 Shen et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama)
ASSIGNEE(S) The Board of Trustees of The University of Alabama (Tuscaloosa, Alabama)
INVENTOR(S) Xiangrong Shen (Tuscaloosa, Alabama);  Edward Sazonov (Northport, Alabama);  Md Rejwanul Haque (Tuscaloosa, Alabama)
ABSTRACT The present disclosure relates to systems and devices for measuring motion of a shoe and tension in the shoelace of the shoe.
FILED Friday, December 10, 2021
APPL NO 17/547369
ART UNIT 2685 — Selective Communication
CURRENT CPC
Fastenings or Attachments of Footwear; Laces in General
A43C 1/003 (20130101)

Diagnosis; Surgery; Identification
A61B 5/112 (20130101)
A61B 5/746 (20130101)
A61B 5/1117 (20130101)
A61B 5/6807 (20130101) Original (OR) Class
A61B 5/7275 (20130101)
A61B 2503/08 (20130101)
A61B 2503/10 (20130101)

Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 71/0619 (20130101)
A63B 2220/836 (20130101)
A63B 2225/50 (20130101)

Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 5/047 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 13/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121392 Hamilton et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Neurasignal, Inc. (Los Angeles, California)
ASSIGNEE(S) Neurasignal, Inc. (Los Angeles, California)
INVENTOR(S) Robert Hamilton (Los Angeles, California);  Corey Thibeault (Los Angeles, California);  Michael O'Brien (Los Angeles, California);  Mina Ranjbaran (Los Angeles, California);  Samuel Thorpe (Los Angeles, California);  Nicolas Canac (Los Angeles, California)
ABSTRACT A system includes a processing circuit configured to receive signals corresponding ultrasound data, extract a blood flow waveform from the signals, the blood flow waveform corresponds to a single pulse of the signals, determine a curvature characteristic of the blood flow waveform based on a plurality of local curvature parameters, and identify a medical condition for the blood flow waveform using the blood flow waveform. Each of the plurality of local curvature parameters indicates a degree to which the blood flow waveform deviates from a straight line at a location on the blood flow waveform.
FILED Monday, November 30, 2020
APPL NO 17/107843
ART UNIT 3797 — Selective Communication
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 8/06 (20130101) Original (OR) Class
A61B 8/461 (20130101)
A61B 8/463 (20130101)
A61B 8/466 (20130101)
A61B 8/488 (20130101)
A61B 8/0808 (20130101)
A61B 8/0816 (20130101)
A61B 8/0891 (20130101)
A61B 8/4218 (20130101)
A61B 8/4227 (20130101)
A61B 8/4236 (20130101)
A61B 8/4245 (20130101)
A61B 8/4281 (20130101)
A61B 8/4477 (20130101)
A61B 8/5207 (20130101)
A61B 8/5223 (20130101)
A61B 8/5292 (20130101)

Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 15/8979 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121627 Manuel et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Michele Viola Manuel (Gainesville, Florida);  Ida E. Svensson Berglund (Chicago, Illinois);  Benjamin G. Keselowsky (Gainesville, Florida);  Malisa Sarntinoranont (Gainesville, Florida);  Harpreet Singh Brar (Hillsboro, Oregon);  Hunter B. Henderson (Gainesville, Florida)
ABSTRACT Embodiments of the present disclosure provide for structures including an alloy of calcium, strontium, and magnesium.
FILED Tuesday, September 27, 2022
APPL NO 17/953407
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 33/06 (20130101)

Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/047 (20130101) Original (OR) Class
A61L 27/54 (20130101)
A61L 27/58 (20130101)
A61L 31/16 (20130101)
A61L 31/022 (20130101)
A61L 31/148 (20130101)
A61L 2300/43 (20130101)
A61L 2300/258 (20130101)
A61L 2300/414 (20130101)
A61L 2430/02 (20130101)
A61L 2430/12 (20130101)
A61L 2430/38 (20130101)

Alloys
C22C 23/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121687 Daniele et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Engineering Education and Centers (EEC)
APPLICANT(S) North Carolina State University (Raleigh, North Carolina)
ASSIGNEE(S) North Carolina State University (Raleigh, North Carolina)
INVENTOR(S) Michael Daniele (Raleigh, North Carolina);  Ethan Marrow (Raleigh, North Carolina)
ABSTRACT A microneedle array including a plurality of microneedles that include nanocellulose or a nanocellulose composite, methods of producing a microneedle array, a device including a microneedle array, and methods of extracting a dermal biofluid or subdermal biofluid by applying a microneedle array.
FILED Tuesday, September 18, 2018
APPL NO 16/647110
ART UNIT 3783 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/150984 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 37/0015 (20130101) Original (OR) Class
A61M 2037/0053 (20130101)
A61M 2037/0061 (20130101)
A61M 2207/10 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 5/00 (20130101)

Compositions of Macromolecular Compounds
C08L 1/02 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12121898 Weitz et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) David A. Weitz (Cambridge, Massachusetts);  Adam R. Abate (Cambridge, Massachusetts)
ABSTRACT The present invention is generally related to systems and methods for producing droplets. The droplets may contain varying species, e.g., for use as a library. In some cases, at least one droplet is used to create a plurality of droplets, using techniques such as flow-focusing techniques. In one set of embodiments, a plurality of droplets, containing varying species, can be divided to form a collection of droplets containing the various species therein. A collection of droplets, according to certain embodiments, may contain various subpopulations of droplets that all contain the same species therein. Such a collection of droplets may be used as a library in some cases, or may be used for other purposes.
FILED Wednesday, January 13, 2021
APPL NO 17/148287
ART UNIT 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Mixing, e.g Dissolving, Emulsifying, Dispersing
B01F 23/41 (20220101)
B01F 33/3011 (20220101)
B01F 33/3021 (20220101)

Chemical or Physical Laboratory Apparatus for General Use
B01L 3/0241 (20130101)
B01L 3/502761 (20130101) Original (OR) Class
B01L 3/502784 (20130101)
B01L 2200/0636 (20130101)
B01L 2200/0652 (20130101)
B01L 2300/0681 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 137/0318 (20150401)
Y10T 137/8593 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122047 Ben-Tzvi et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia)
ASSIGNEE(S) VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (Blacksburg, Virginia)
INVENTOR(S) Pinhas Ben-Tzvi (Blacksburg, Virginia);  Wael Saab (Blacksburg, Virginia);  William Rone (Blacksburg, Virginia);  Yujiong Liu (Blacksburg, Virginia)
ABSTRACT An articulated multi-link robotic tail (MLRT) system is provided comprising a rigid housing, an actuation unit coupled to the rigid housing, and an MLRT having a proximal end that is coupled to the rigid housing and a distal end opposite the proximal end. The MLRT comprises N segments, where N is a positive integer that is greater than or equal to one. Each segment comprises i links, where i is a positive integer that is greater than or equal to two. Each link is mechanically coupled to an actuator of the actuation unit and capable of being actuated by the actuator to which it is mechanically coupled to adjust a pitch, yaw and roll of the MLRT. The articulated MLRT system is well suited for being integrated with a mobile robot to assist in stabilizing and maneuvering the mobile robot.
FILED Thursday, March 17, 2022
APPL NO 17/697353
ART UNIT 3656 — Material and Article Handling
CURRENT CPC
Manipulators; Chambers Provided With Manipulation Devices
B25J 9/06 (20130101) Original (OR) Class
B25J 9/08 (20130101)
B25J 9/042 (20130101)
B25J 17/0241 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122687 Hsiao et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) The Research Foundation for The State University of New York (Albany, New York)
ASSIGNEE(S) The Research Foundation for the State University of New York (Albany, New York)
INVENTOR(S) Benjamin S. Hsiao (Setauket, New York);  Priyanka Sharma (East Setauket, New York);  Sunil Kumar Sharma (East Setauket, New York);  Ken I. Johnson (Port Jefferson Station, New York)
ABSTRACT A method of treating contaminated water, such as wastewater, with carboxylated cellulose to remove ammonium and nitrogen-containing impurities is claimed. Carboxylated cellulose extracted by nitro-oxidation has negatively-charged functionality and forms an aggregate when exposed to positively-charged impurities in contaminated water. The aggregate, nitrogen-containing impurities, and by-products from the nitro-oxidation process can be isolated to provide a fertilizer or fertilizer component.
FILED Wednesday, August 28, 2019
APPL NO 17/267683
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 20/24 (20130101)
B01J 20/28023 (20130101)
B01J 2220/4831 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/286 (20130101) Original (OR) Class
C02F 2101/16 (20130101)
C02F 2303/16 (20130101)

Organic Fertilisers Not Covered by Subclasses C05B, C05C, e.g Fertilisers From Waste or Refuse
C05F 7/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123840 Ros et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Biological Infrastructure (DBI)
APPLICANT(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona)
INVENTOR(S) Alexandra Ros (Phoenix, Arizona);  Daihyun Kim (Mesa, Arizona);  Austin Echelmeier (Tempe, Arizona);  Jorvani Cruz Villarreal (Tempe, Arizona);  Ana Egatz-Gomez (Phoenix, Arizona);  Sebastian Quintana (Phoenix, Arizona)
ABSTRACT Methods and systems are provided for serial femtosecond crystallography for reducing the vast amount of waste of injected crystals practiced with traditional continuous flow injections. A micrometer-scale 3-D printed water-in-oil droplet generator device includes an oil phase inlet channel, an aqueous phase inlet channel, a droplet flow outlet channel, and two embedded non-contact electrodes. The inlet and outlet channels are connected internally at a junction. The electrodes comprise gallium metal injected within the 3-D printed device. Voltage across the electrodes generates water-in-oil droplets, determines a rate for a series of droplets, or triggers a phase shift in the droplets. An external trigger generates the droplets based on the frequency of an XFEL utilized in droplet detection, thereby synchronizing a series of droplets with x-ray pulses for efficient crystal detection. The generated droplets can be coupled to an SFX with XFEL experiment compatible with common liquid injector such as a GDVN.
FILED Tuesday, November 07, 2023
APPL NO 18/504091
ART UNIT 3753 — Fluid Handling and Dispensing
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/0241 (20130101)
B01L 3/50273 (20130101)
B01L 2300/0867 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 80/00 (20141201)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/20025 (20130101) Original (OR) Class
G01N 2223/602 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123881 Wandinger-Ness et al.
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
National Institute of General Medical Sciences (NIGMS)
National Institute of Neurological Disorders and Stroke (NINDS)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) UNM Rainforest Innovations (Albuquerque, New Mexico)
ASSIGNEE(S) UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico)
INVENTOR(S) Angela Wandinger-Ness (Albuquerque, New Mexico);  Tione Buranda (Albuquerque, New Mexico);  Peter Simons (Albuquerque, New Mexico);  Stephen Young (Albuquerque, New Mexico)
ABSTRACT The present invention is directed to the discovery that RapI-GTP, Rac1-GTP and Flt3-L can be used as Biomarkers for the early detection of sepsis in patients suspected of a bacterial infection which presents as sepsis or is likely to produce sepsis. In particular, the present invention is directed to methods, assays and kits which may be used to distinguish sepsis (infection) from systematic inflammatory response caused by sterile inflammation in trauma patients. The method may be used to diagnose bacteria infection and/or sepsis and monitor therapy of a patient to allow modification of treatment and/or cessation of treatment.
FILED Thursday, April 18, 2019
APPL NO 17/048941
ART UNIT 1678 — Fluid Handling and Dispensing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 15/14 (20130101)
G01N 33/563 (20130101)
G01N 33/588 (20130101)
G01N 33/6893 (20130101) Original (OR) Class
G01N 2800/26 (20130101)
G01N 2800/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123912 Bhunia et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Education and Human Resources (EHR)
Division of Graduate Education (DGE)
APPLICANT(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Incorporated (Gainesville, Florida)
INVENTOR(S) Swarup Bhunia (Gainesville, Florida);  Christopher Vega (Gainesville, Florida);  Reiner Dizon (Gainesville, Florida);  Rohan Reddy Kalavakonda (Gainesville, Florida);  Patanjali Sristi Lakshmiprasanna Sriramakumara (Gainesville, Florida)
ABSTRACT A reconfigurable JTAG includes, in part, a core logic, a boundary scan chain cell, one or more reconfigurable blocks (RBs), and a reconfigurable block (RB) programming module. The RBs may include, in part, one or more reconfigurable boundary scan chain blocks (RBB) adapted to couple the boundary scan chain cell to the core logic and to input/output (I/O) ports of the reconfigurable JTAG. The RBs may also include, in part, one or more additional reconfigurable logic (ARL) blocks to provide enhanced logic for locking operations. The RB programmable module may communicate with a memory storing data for configuring the RBBs and ARLs. The RB programming module may configure the RBBs and ARLs based at least in part on the data stored in the memory to disable access to the I/O ports of the JTAG. The RB programming module may configure the RBBs to encrypt the I/O ports in accordance with a cipher algorithm. The RB programming module may also configure the RBBs and ARLs to compare a counter's count to a predefined time and lock the I/O ports after an expiration of the predefined time.
FILED Thursday, April 28, 2022
APPL NO 17/661232
ART UNIT 2111 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 31/2815 (20130101)
G01R 31/31713 (20130101)
G01R 31/318533 (20130101)
G01R 31/318536 (20130101) Original (OR) Class
G01R 31/318555 (20130101)
G01R 31/318588 (20130101)
G01R 31/318597 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123938 Babakhani et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Aydin Babakhani (Los Angeles, California);  Seyedmohammadreza Razavian (San Diego, California);  Mahdi Assefzadeh (Colorado Springs, Colorado);  Mostafa Hosseini (Los Angeles, California)
ABSTRACT Systems and methods for modulation and demodulation using a micro-Doppler effect are described. In an embodiment, the method includes radiating, using a picosecond pulse generator with an antenna, a train of THz pulses that form a frequency comb, where the frequency comb is reflected from an object such that the frequency several tones in the frequency comb are shifted based on the speed of the object and demodulating the reflected frequency comb to recover a THz Doppler signature of the object.
FILED Monday, September 12, 2022
APPL NO 17/931301
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 7/28 (20130101)
G01S 7/4095 (20210501)
G01S 13/505 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12124629 McDaniel et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona);  Mozest Goldberg (Les Baux de Provence, France)
ASSIGNEE(S) Mozest Goldberg (Les Baux de Provence, France);  Arizona Board of Regents on Behalf of Arizona State University (Tempe, Arizona)
INVENTOR(S) Troy McDaniel (Gilbert, Arizona);  Mozest Goldberg (Les Baux de Provence, France);  Hemanth Kumar Demakethepalli Venkateswara (Tempe, Arizona);  Sethuraman Panchanathan (Gilbert, Arizona);  Vishnu Prateek Kakaraparthi (Tempe, Arizona)
ABSTRACT A system includes a wearable device including a camera. The system further includes at least one processor that can identify objects from video data generated by the camera and monitor how an individual wearing the wearable device manipulates the objects according to predetermined micro-activities of interest to infer an action by the individual.
FILED Thursday, April 06, 2023
APPL NO 18/296908
ART UNIT 2627 — Selective Visual Display Systems
CURRENT CPC
Electric Digital Data Processing
G06F 3/014 (20130101) Original (OR) Class

Image or Video Recognition or Understanding
G06V 40/28 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12125638 Fan
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Texas Tech University System (Lubbock, Texas)
ASSIGNEE(S) Texas Tech University System (Lubbock, Texas)
INVENTOR(S) Zhaoyang Fan (Lubbock, Texas)
ABSTRACT High-frequency supercapacitors that can respond at kilohertz frequencies (AC-supercapacitors). The electrodes of the AC-supercapacitors include edge oriented graphene (EOG) electrodes or carbon nanofiber network (CNN) electrodes. The EOG electrodes are formed by utilizing a plasma and feedstock carbon gas to carbonize cellulous paper and deposit graphene implemented in one step. The CNN electrodes are formed by pyrolyzing a carbon nanofiber network utilizing a plasma.
FILED Tuesday, November 03, 2020
APPL NO 17/088044
ART UNIT 2848 — Electrical Circuits and Systems
CURRENT CPC
Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type
H01G 11/24 (20130101)
H01G 11/28 (20130101)
H01G 11/36 (20130101) Original (OR) Class
H01G 11/44 (20130101)
H01G 11/48 (20130101)
H01G 11/52 (20130101)
H01G 11/86 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12125993 Choi et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Kyoung-Shin Choi (Fitchburg, Wisconsin);  Dohwan Nam (Madison, Wisconsin);  Margaret Lumley (Madison, Wisconsin)
ABSTRACT Dual-functional energy storage systems that couple ion extraction and recovery with energy storage and release are provided. The dual-functional energy storage systems use ion-extraction and ion-recovery as charging processes. As the energy used for the ion extraction and ion recovery processes is not consumed, but rather stored in the system through the charging process, and the majority of the energy stored during charging can be recovered during discharging, the dual-functional energy storage systems perform useful functions, such as solution desalination or lithium-ion recovery with a minimal energy input, while storing and releasing energy like a conventional energy storage system.
FILED Thursday, July 20, 2023
APPL NO 18/224344
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/38 (20130101)
H01M 4/5825 (20130101)
H01M 8/184 (20130101)
H01M 10/36 (20130101)
H01M 10/44 (20130101) Original (OR) Class
H01M 10/054 (20130101)
H01M 10/4214 (20130101)
H01M 2300/0002 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12126093 Jalili et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Hossein Jalili (Atlanta, Georgia);  Omeed Momeni (Davis, California)
ABSTRACT In one aspect, a system that provides a lens-integrated reconfigurable radiating source capable of two-dimensional continuous beam steering is disclosed. The system can include a silicon (Si) chip that further comprises a two-dimensional (2D) array of pixel sources/unit cells, wherein each unit cell in the 2D array includes an on-chip antenna for radiating power. The system further includes Si lens coupled to the silicon chip for controlling a directivity of a radiation beam generated by the chip. Note that the unit cells in the 2D array of unit cells can be independently activated to generate high-directivity radiation beams in a discrete set of firing angles. Moreover, the 2D array is configured to effectuate injection locking between adjacent unit cells in the 2D array when the adjacent unit cells are turned on simultaneously, wherein the injection locking effectuates a coherent radiation beam that can be continuously steered within a scanning range with fine resolution.
FILED Tuesday, February 01, 2022
APPL NO 17/590566
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Antennas, i.e Radio Aerials
H01Q 3/26 (20130101)
H01Q 3/30 (20130101)
H01Q 3/38 (20130101)
H01Q 3/46 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12126303 Liu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Luqiao Liu (Brookline, Massachusetts);  Justin Hou (Cambridge, Massachusetts);  Pengxiang Zhang (Cambridge, Massachusetts)
ABSTRACT An oscillator comprising, a cavity wherein the cavity comprises an electrical conductor. The oscillator comprising an electrical insulator disposed on a surface of the cavity; and a heterostructure disposed on a surface of the electrical insulator and having a first end and a second end, the heterostructure comprising one or more spin current source layers and one or more magnetic material layers. In response to an electrical current passed through the spin current source, an oscillation occurs in a plurality of magnetic domains of the magnetic material, wherein the oscillations have substantially the same phase.
FILED Friday, March 31, 2023
APPL NO 18/193885
ART UNIT 2849 — Electrical Circuits and Systems
CURRENT CPC
Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 10/329 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 1/02 (20130101)

Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits
H03B 15/006 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12127006 D'Oro et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Salvatore D'Oro (Allston, Massachusetts);  Tommaso Melodia (Newton, Massachusetts);  Francesco Restuccia (Boston, Massachusetts);  Leonardo Bonati (Boston, Massachusetts)
ABSTRACT Methods and systems are provided for allocating resources to users in a wireless network including a plurality of edge nodes that provide wireless network access and multi-access edge computing functions. Slice requests are received from the users for a type of resource, including one or more of networking resources, storage resources, and computation resources. A set of slice requests to be admitted is determined based on resource availability constraints among one or more of the networking resources, the storage resources, and the computation resources at each edge node.
FILED Thursday, July 01, 2021
APPL NO 17/365070
ART UNIT 2641 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Wireless Communication Networks
H04W 4/021 (20130101)
H04W 16/10 (20130101) Original (OR) Class
H04W 16/18 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12127059 Melodia et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Computer and Network Systems (CNS)
APPLICANT(S) Northeastern University (Boston, Massachusetts)
ASSIGNEE(S) Northeastern University (Boston, Massachusetts)
INVENTOR(S) Tommaso Melodia (Newton, Massachusetts);  Salvatore D'Oro (Allston, Massachusetts);  Michele Polese (Boston, Massachusetts);  Leonardo Bonati (Boston, Massachusetts)
ABSTRACT A radio access network (RAN) intelligent controller (RIC) and corresponding method may be implemented within RAN and in next-generation cellular networks to improve performance. The RIC comprises an interface to a RAN and further comprises a data-driven logic unit. The data-driven logic unit (i) produces, based on data received from the RAN via the interface, a representation describing a state of the RAN and (ii) based on the representation describing the state, instructs an action associated with at least one network element. The interface transmits a message based on the action instructed. The message is to be routed to the at least one network element. The representation is based on a context of the RAN. The message transmitted enabling re-configuration of the at least one network element. The re-configuration improves performance of the at least one network element within the context.
FILED Tuesday, November 23, 2021
APPL NO 17/456361
ART UNIT 2473 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 17/336 (20150115)

Wireless Communication Networks
H04W 28/24 (20130101)
H04W 28/0236 (20130101)
H04W 28/0967 (20200501)
H04W 36/06 (20130101) Original (OR) Class
H04W 36/30 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 12121932 Abraham et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) U.S.A. as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Nithin S. Abraham (Silver Spring, Maryland);  Mark M. Hasegawa (Highland, Maryland);  Sharon A. Straka (Glenelg, Maryland);  John C. Petro (Greenbelt, Maryland)
ABSTRACT A method of coating a substrate with a white molecular coating. A colloidal based primer is prepared having on a mass basis between 30-40% suspensions of fine-sized spherical particles of nonporous silica dispersed in liquid phase. The primer is applied to the substrate and allowed to dry. A molecular adsorber coating is prepared by treating a zeolite with a colloidal silica binder thereby providing a treated pigment having a mass ratio of the colloidal silica to the zeolite is in a range of 2.0 to 2.6, then processing the treated pigment into a powder thereby facilitating sprayability and then mixing said treated zeolite with a colloidal solution containing silica. The coating is then sprayed onto the primer and allowed to dry. The resultant coating provides adequate bond stability and strength necessary for flight applications within an environment for vacuum of space applications.
FILED Friday, December 18, 2020
APPL NO 17/126836
ART UNIT 1715 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Processes for Applying Fluent Materials to Surfaces, in General
B05D 1/02 (20130101)
B05D 3/142 (20130101)
B05D 3/0272 (20130101)
B05D 3/0406 (20130101)
B05D 7/544 (20130101) Original (OR) Class

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 1/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122539 Choi et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Sang H. Choi (Poquoson, Virginia);  Robert W. Moses (Poquoson, Virginia);  Dennis M. Bushnell (Hampton, Virginia)
ABSTRACT The present disclosure is directed to a system including a nuclear thermal rocket or a nuclear reactor, at least one nuclear electric thruster coupled to the nuclear thermal rocket or the nuclear reactor, and a Nuclear Thermionic Avalanche Cell (NTAC) configured to generate electrical power. The NTAC cell may be positioned around a nuclear reactor core of the nuclear thermal rocket or the nuclear reactor, and the nuclear electric thruster may be powered by the NTAC generated electrical power.
FILED Wednesday, December 29, 2021
APPL NO 17/564911
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/408 (20130101) Original (OR) Class

Producing a Reactive Propulsive Thrust, Not Otherwise Provided for
F03H 1/0037 (20130101)

Nuclear Power Plant
G21D 5/02 (20130101)
G21D 7/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12125636 Moses et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
ASSIGNEE(S) UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Robert W. Moses (Poquoson, Virginia);  Foy M. Cheatwood (Norfolk, Virginia);  Christopher O. Johnston (Yorktown, Virginia);  Sergey Macheret (West Lafayette, Indiana);  Bernard Parent (Tucson, American Samoa);  Justin Little (Seattle, Washington)
ABSTRACT A magnetohydrodynamic (MHD) flow control mechanism is described which substantially improves the existing processes in that smaller magnetic fields, requiring far less mass, are placed away from the forebody of the spacecraft to produce Lorentz forces that augment the lift and the drag forces for guidance, navigation, and control of the spacecraft.
FILED Friday, April 22, 2022
APPL NO 17/727009
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Cosmonautics; Vehicles or Equipment Therefor
B64G 1/62 (20130101)
B64G 1/2421 (20230801)

Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties
H01F 7/02 (20130101)
H01F 7/20 (20130101)
H01F 7/0273 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 12123817 Barber et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia)
INVENTOR(S) Jeffrey Barber (Vineland, New Jersey);  James C. Weatherall (Linwood, New Jersey);  Duane Karns (Mays Landing, New Jersey);  Barry T. Smith (Egg Harbor City, New Jersey)
ABSTRACT A device to determine density includes a housing, a first transducer disposed in the housing at a first position, and a second transducer disposed in the housing at a second position. The second transducer is located a distance from the first transducer. The device also includes a controller that reads a first output from the first transducer, and reads a second output from the second transducer. The controller determines a density of a liquid based on the first output, the second output, and the distance.
FILED Tuesday, August 15, 2023
APPL NO 18/234047
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 11/00 (20130101) Original (OR) Class
G01N 21/45 (20130101)
G01N 27/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12126487 Clark et al.
FUNDED BY
Department of Homeland Security (DHS)
Science and Technology Directorate (DHS-ST)
APPLICANT(S) Two Six Labs, LLC (Arlington, Virginia)
ASSIGNEE(S) Two Six Labs, LLC (Arlington, Virginia)
INVENTOR(S) Chae A. Clark (Arlington, Virginia);  Robert P. Gove, Jr. (Reston, Virginia);  Violet Lingenfelter (Arlington, Virginia);  Anthony Wong (Arlinggton, Virginia)
ABSTRACT A network disruption detection engine gathers and stores network routing path update messages that routinely modify routing tables used by internet routers for transporting message traffic between a source and a destination. Routing path messages continually maintain a network transport infrastructure both for intranets used for particular entities such as corporations, and internet traffic between arbitrary source and destination nodes. Major disruptions or outages typically result in an increase in routing path messages, typically focused on a particular set, region or network entity where the disruption occurred, as other routing entities seek to avoid the troubled region. Analysis of this sudden activity of routing messages and extracting message content about the network region they seek to avoid allows identification and queries of a widespread network outage.
FILED Tuesday, June 13, 2023
APPL NO 18/209149
ART UNIT 2454 — Computer Networks
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 41/06 (20130101) Original (OR) Class
H04L 41/12 (20130101)
H04L 41/0677 (20130101)
H04L 43/50 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 12123324 Kryj-Kos et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) GENERAL ELECTRIC COMPANY (Schenectady, New York);  General Electric Company Polska Sp. z o.o. (Warsaw, Poland)
ASSIGNEE(S) General Electric Company (Evendale, Ohio);  General Electric Company Polska Sp. Z o.o. (Warsaw, Poland)
INVENTOR(S) Elzbieta Kryj-Kos (Liberty Township, Ohio);  Piotr Jerzy Kulinski (Warsaw, Poland);  Pawel Adam Lewicki (Warsaw, Poland);  Ruolong Ma (Mason, Ohio);  Wendy Wenling Lin (Montgomery, Ohio);  Patrick Keene Clements (Cincinnati, Ohio)
ABSTRACT A method of electroforming an airfoil comprising an airfoil body. The method comprising electroforming a metal edge shell over a filler, located at a leading edge of the airfoil body, and over the airfoil body. The filler can be encapsulated within the metal edge shell and the metal edge shell has a sculpted leading edge defining a non-linear pattern.
FILED Wednesday, June 28, 2023
APPL NO 18/343013
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 9/02 (20130101) Original (OR) Class

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2230/31 (20130101)
F05D 2240/121 (20130101)
F05D 2250/185 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12126427 Zhang et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
ASSIGNEE(S) The Board of Regents of the University of Oklahoma (Norman, Oklahoma)
INVENTOR(S) Yan Zhang (Norman, Oklahoma);  Hernan A. Suarez Montalvo (Norman, Oklahoma);  Sudantha Perera (Broomfield, Colorado)
ABSTRACT An instrument landing system comprises: a wideband antenna configured to receive signals in a VHF band; and a receiver coupled to the wideband antenna and configured to implement SDR functions to analyze the signals for a flight inspection. A UAS comprises: an instrument landing system comprising: a wideband antenna configured to receive signals in a VHF band; and a receiver coupled to the wideband antenna and configured to implement SDR functions to analyze the signals for a flight inspection. A method comprises: receiving, using a wideband antenna, signals in a VHF band; and implementing, using a receiver coupled to the wideband antenna, SDR functions to analyze the signals for a flight inspection.
FILED Tuesday, July 20, 2021
APPL NO 17/380960
ART UNIT 2465 — Multiplex and VoIP
CURRENT CPC
Transmission
H04B 1/16 (20130101)
H04B 7/18506 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 12121526 Simard
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) University of Maryland, Baltimore (Baltimore, Maryland);  The United States of America as Represented by the Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia);  University of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S) J. Marc Simard (Baltimore, Maryland)
ABSTRACT The present invention concerns protection of an organ or tissue outside of the central nervous system following an ischemic episode. In particular aspects, the invention concerns organ preservation for transplantation, angina pectoris, kidney reperfusion injury, and so forth. In specific embodiments, the organ is subjected to an inhibitor of an NCCa-ATP channel that is regulated by SUR1. Exemplary inhibitors include sulfonylurea compounds, such as glibenclamide, for example.
FILED Monday, December 21, 2020
APPL NO 17/128955
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/57 (20130101) Original (OR) Class
A61K 31/64 (20130101)
A61K 31/427 (20130101)
A61K 31/565 (20130101)
A61K 38/00 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 9/10 (20180101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/6872 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122853 Zimering
FUNDED BY
Department of Veterans Affairs (DVA)
APPLICANT(S) The United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia)
ASSIGNEE(S) The United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Mark B. Zimering (Lyons, New Jersey)
ABSTRACT Disclosed herein, are decoy peptides or polypeptides capable of inhibiting binding of 5-HT2A autoantibodies to a second extracellular loop region of the 5-HT2A receptor, and a pharmaceutical composition containing the decoy peptides or polypeptides and methods of use.
FILED Friday, March 04, 2022
APPL NO 17/687029
ART UNIT 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/445 (20130101)
A61K 31/517 (20130101)
A61K 38/10 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 3/10 (20180101)

Peptides
C07K 7/08 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 12122819 Antipov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Silver Creek Pharmaceuticals, Inc. (San Francisco, California)
ASSIGNEE(S) Silver Creek Pharmaceuticals, Inc. (San Francisco, California)
INVENTOR(S) Laura D. J. Antipov (Oakland, California);  Shawdee Eshghi (Oakland, California);  Kristopher M. Kuchenbecker (Phoenix, Arizona);  Bjorn L. Millard (Orinda, California);  Matthew D. Onsum (El Cerrito, California);  Andrea D. Nickerson (San Francisco, California);  Timothy R. Stowe (San Francisco, California);  Yan Zhang (San Francisco, California)
ABSTRACT Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair or regenerate damaged or diseased tissue.
FILED Thursday, February 10, 2022
APPL NO 17/668825
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 38/00 (20130101)

Peptides
C07K 14/47 (20130101)
C07K 14/65 (20130101) Original (OR) Class
C07K 14/765 (20130101)
C07K 2319/33 (20130101)
C07K 2319/035 (20130101)
C07K 2319/75 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12122975 Bailey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
Small Business Technology Transfer (STTR)
APPLICANT(S) Novum Nano, LLC (Rapid City, South Dakota);  South Dakota Board of Regents (Pierre, South Dakota)
ASSIGNEE(S) Novum Nano, LLC (Rapid City, South Dakota);  South Dakota Board of Regents (Pierre, South Dakota)
INVENTOR(S) Craig Bailey (Rapid City, South Dakota);  Greg Christensen (Hermosa, South Dakota);  Haiping Hong (Rapid City, South Dakota)
ABSTRACT An engine oil additive includes carbon nanotubes and boron nitride particulates dispersed within a fluid. The additive is configured to be mixed with a quantity of oil such that the quantity of oil has a concentration from 0.05 to 0.5 grams of carbon nanotubes and of boron nitride particulates per quart of oil to improve the lubricity of the oil. The additive improves the horsepower and torque of the engine while reducing fuel consumption. The carbon nanotubes have an —OH functionalized exterior surface. The carbon nanotubes have a diameter from 1 nanometer to 50 nanometers and have a length from 1 micron to 1000 microns. The boron nitride particulates are hex-boron nitride structures having an average size from 30 nanometers to 500 nanometers.
FILED Monday, April 04, 2022
APPL NO 17/713053
ART UNIT 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Lubricating Compositions; Use of Chemical Substances Either Alone or as Lubricating Ingredients in a Lubricating Composition
C10M 125/02 (20130101)
C10M 125/26 (20130101)
C10M 169/04 (20130101) Original (OR) Class
C10M 2201/14 (20130101)
C10M 2201/041 (20130101)
C10M 2201/082 (20130101)
C10M 2203/003 (20130101)

Indexing Scheme Associated With Subclass C10M Relating to Lubricating Compositions
C10N 2020/06 (20130101)
C10N 2040/25 (20130101)
C10N 2070/02 (20200501)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 12123062 Singh et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S) The Florida State University Research Foundation, Inc. (Tallahassee, Florida);  The United State of America, as presented by the Secretary of Agriculture (Washington, District of Columbia)
ASSIGNEE(S) The Florida State University Research Foundation, Inc. (Tallahassee, Florida);  The United States of America, as presented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Prashant Singh (Tallahassee, Florida);  Joseph M. Bosilevac (Clay Center, Nebraska)
ABSTRACT Disclosed herein are methods and kits for quantifying the presence of a microorganism in a sample. Specifically, disclosed are methods for quantifying a pathogen in a sample, such as a food sample, to determine if the levels of pathogen present in the sample are within an acceptable range.
FILED Friday, November 11, 2022
APPL NO 18/054778
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/689 (20130101) Original (OR) Class
C12Q 2600/16 (20130101)

Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms
C12R 2001/42 (20210501)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 12123786 Gao et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) The Regents of the University of Colorado (Denver, Colorado)
ASSIGNEE(S) The Regents of the University of Colorado, a body corporate (Denver, Colorado);  National Institute of Standards and Technology (Gaithersburg, Maryland)
INVENTOR(S) Jiansong Gao (Boulder, Colorado);  Maxime Bernard Jacques Malnou (Boulder, Colorado);  Michael Robert Vissers (Broomfield, Colorado);  Jordan Wheeler (Arvada, Colorado)
ABSTRACT Technology is disclosed herein that the enhances the measurability of on-chip temperature in a cryogenic quantum computing environment. In an implementation, transceiver circuitry sends a probe signal through a target device. A lumped-element resonator device that is proximate to the surface of the target device interacts with the probe signal and modulates the probe signal. Processing circuitry reads the probe signal through the target device, and responsively measures the resonance frequency of the lumped-element resonator device. The processing circuitry correlates the measured resonance frequency with a temperature and responsively determines the temperature of the target device.
FILED Thursday, September 16, 2021
APPL NO 17/476832
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for
G01K 1/14 (20130101)
G01K 7/006 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Education (ED) 

US 12121360 Huggins et al.
FUNDED BY
Department of Education (ED)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
ASSIGNEE(S) THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan)
INVENTOR(S) Jane E. Huggins (Fenton, Michigan);  Seth Warschausky (Ann Arbor, Michigan);  Ramses Eduardo Alcaide (Ann Arbor, Michigan)
ABSTRACT Methods, systems, apparatus, and non-transitory computer readable media are disclosed utilizing brain-computer interfaces (BCIs). Various embodiments are disclosed to allow a user to directly select multiple-choice answers, to provide motorized wheelchair controls, and to allow a user to play a game via the BCI. When used in a cognitive assessment test, embodiments include the administration of unmodified standardized tests with results in the same or a similar format as those taken without a BCI. Various embodiments are disclosed to improve the accuracy of BCI test administration using a three-step process for each test question, which includes determining whether the user intends to select an answer, monitoring user brain activity to determine a selected answer, and verifying the selected answer. In addition, the selected answer may be verified by monitoring user brain activity in accordance with a hold-release process to determine whether a user intends to initiate a state change.
FILED Tuesday, July 06, 2021
APPL NO 17/368207
ART UNIT 2115 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/372 (20210101)
A61B 5/374 (20210101)
A61B 5/378 (20210101)
A61B 5/742 (20130101)
A61B 5/4088 (20130101) Original (OR) Class
A61B 5/7221 (20130101)
A61B 5/7264 (20130101)
A61B 5/7267 (20130101)
A61B 5/7282 (20130101)
A61B 5/7435 (20130101)

Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 2/72 (20130101)
A61F 4/00 (20130101)

Electric Digital Data Processing
G06F 3/015 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 7/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of the Interior (DOI) 

US 12121860 Sirkar et al.
FUNDED BY
Department of the Interior (DOI)
Bureau of Reclamation (USBR)
APPLICANT(S) New Jersey Institute of Technology (Newark, New Jersey);  Applied Membrane Technology, Inc. (Minnetonka, Minnesota)
ASSIGNEE(S) New Jersey Institute of Technology (Newark, New Jersey);  Applied Membrane Technology, Inc. (Minnetonka, Minnesota)
INVENTOR(S) Kamalesh Sirkar (Bridgewater, New Jersey);  Dhananjay Singh (Kearny, New Jersey);  Lin Li (Kearny, New Jersey);  Thomas J. McEvoy (Tofte, Minnesota)
ABSTRACT Exemplary embodiments in desalination by direct contact membrane distillation present a cylindrical cross-flow module containing high-flux composite hydrophobic hollow fiber membranes. The present embodiments are directed to a model that has been developed to describe the observed water production rates of such devices in multiple brine feed introduction configurations. The model describes the observed water vapor production rates for different feed brine temperatures at various feed brine flow rates. The model flux predictions have been explored over a range of hollow fiber lengths to compare the present results with those obtained earlier from rectangular modules which had significantly shorter hollow fibers.
FILED Wednesday, December 21, 2022
APPL NO 18/085724
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Separation
B01D 61/366 (20130101) Original (OR) Class
B01D 61/3641 (20220801)
B01D 63/02 (20130101)
B01D 63/04 (20130101)
B01D 2313/10 (20130101)
B01D 2313/12 (20130101)
B01D 2313/21 (20130101)
B01D 2315/10 (20130101)
B01D 2325/38 (20130101)

Treatment of Water, Waste Water, Sewage, or Sludge
C02F 1/447 (20130101)
C02F 2103/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Non-Profit Organization (NPO) 

US 12121028 Mandadi et al.
FUNDED BY
Non-Profit Organization (NPO)
Foundation for Food and Agriculture Research (FFAR)
APPLICANT(S) The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) The Texas A and M University System (College Station, Texas)
INVENTOR(S) Kranthi Mandadi (Weslaco, Texas);  Manikandan Ramasamy (Weslaco, Texas);  Prakash Niraula (Weslaco, Texas);  Sonia Irigoyen (Weslaco, Texas)
ABSTRACT Applicants have developed novel methods and compositions for treating, preventing or ameliorating the effects plant phytopathogen infestation in plants, including of Candidatus liberibacter spp. the causal agents of citrus greening and potato zebrachip disease. Novel compositions include one or more active agents of aminocaproic acid, carbinoxamine maleate, chloroxylenol, chlorpropamide, cinoxacin, duartin, and cyclopentolate hydrochloride as well as their derivatives, or salt/acid forms thereof. Methods of preventing disease development and infestation by plant pathogens are disclosed as well as methods of making, using and producing such compositions.
FILED Thursday, May 27, 2021
APPL NO 17/303367
ART UNIT 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators
A01N 31/04 (20130101)
A01N 33/04 (20130101)
A01N 37/44 (20130101)
A01N 41/10 (20130101)
A01N 43/42 (20130101)
A01N 43/90 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 12122666 Duan et al.
FUNDED BY
APPLICANT(S) Northrop Grumman Systems Corporation (Falls Church, Virginia)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) Dah-Weih Duan (Torrance, California);  Elizabeth T. Kunkee (Manhattan Beach, California);  Martin E. Roden (Long Beach, California);  Laura M. Woo (Rossmoor, California)
ABSTRACT A microelectronics H-frame device includes: a stack of two or more substrates wherein the substrate stack comprises a top substrate and a bottom substrate, wherein bonding of the top substrate to the bottom substrate creates a vertical electrical connection between the top substrate and the bottom substrate, wherein the top surface of the top substrate comprises top substrate top metallization, wherein the bottom surface of the bottom substrate comprises bottom substrate bottom metallization; mid-substrate metallization located between the top substrate and the bottom substrate; a micro-machined top cover bonded to a top side of the substrate stack; and a micro-machined bottom cover bonded to a bottom side of the substrate stack.
FILED Thursday, March 11, 2021
APPL NO 17/198700
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Microstructural Devices or Systems, e.g Micromechanical Devices
B81B 7/0006 (20130101) Original (OR) Class
B81B 7/0019 (20130101)
B81B 2207/07 (20130101)
B81B 2207/091 (20130101)

Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 3/001 (20130101)
B81C 3/005 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12123311 Shockey et al.
FUNDED BY
APPLICANT(S) Raytheon Technologies Corporation (Farmington, Connecticut)
ASSIGNEE(S) RTX CORPORATION (Farmington, Connecticut)
INVENTOR(S) Brian D. Shockey (Middletown, Connecticut);  Joseph B. Phelps (Rocky Hill, Connecticut)
ABSTRACT An assembly is provided for a turbine engine. This turbine engine assembly includes a rotating assembly and a sensor. The rotating assembly is configured to rotate about an axis. The rotating assembly includes an engine shaft and a stack nut threaded onto the engine shaft. The stack nut includes a castellated periphery. The sensor is configured to measure fluctuations in a magnetic field induced by the castellated periphery during rotation of the rotating assembly about the axis.
FILED Friday, May 26, 2023
APPL NO 18/202743
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Non-positive Displacement Machines or Engines, e.g Steam Turbines
F01D 5/02 (20130101)
F01D 17/02 (20130101) Original (OR) Class
F01D 21/003 (20130101)

Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants
F05D 2220/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, October 22, 2024.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20241022.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

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