FedInvent™ Patents

Patent Details for Tuesday, November 05, 2024 

This page was updated on Tuesday, November 12, 2024 at 04:34 AM GMT

Department of Health and Human Services (HHS) 

US 12133494 Moehs et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Arcadia Biosciences, Inc. (Davis, California)
ASSIGNEE(S) ARCADIA BIOSCIENCES, INC. (Davis, California)
INVENTOR(S) Charles Paul Moehs (Seattle, Washington);  William J. Austill (Seattle, Washington);  Dayna Loeffler (Seattle, Washington);  Jessica Mullenberg (Seattle, Washington)
ABSTRACT Plants with reduced gluten grains and compositions thereof are disclosed herein.
FILED Tuesday, December 06, 2022
APPL NO 18/062364
ART UNIT 1662 — Plants
CURRENT CPC
New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques
A01H 1/06 (20130101)
A01H 5/10 (20130101)
A01H 6/4678 (20180501) Original (OR) Class

Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General
A23L 7/198 (20160801)

Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages
A23V 2002/00 (20130101)

Peptides
C07K 14/415 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133515 Church et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) George M. Church (Brookline, Massachusetts);  Luhan Yang (Somerville, Massachusetts);  Marc Guell (Barcelona, Spain)
ABSTRACT A method of modulating some or all copies of a gene in a cell is provided including introducing into a cell one or more ribonucleic acid (RNA) sequences that comprise a portion that is complementary to all or a portion of each of the one or more target nucleic acid sequences, and a nucleic acid sequence that encodes a Cas protein and maintaining the cells under conditions in which the Cas protein is expressed and the Cas protein binds and modulates the one or more target nucleic acid sequences in the cell.
FILED Friday, December 11, 2020
APPL NO 17/118684
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0273 (20130101)
A01K 67/0275 (20130101) Original (OR) Class
A01K 67/0276 (20130101)
A01K 2207/05 (20130101)
A01K 2207/10 (20130101)
A01K 2227/108 (20130101)
A01K 2267/025 (20130101)

Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids
C07H 21/02 (20130101)
C07H 21/04 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 15/63 (20130101)
C12N 15/85 (20130101)
C12N 15/907 (20130101)
C12N 15/1132 (20130101)
C12N 15/8509 (20130101)
C12N 2310/20 (20170501)
C12N 2740/10062 (20130101)
C12N 2800/80 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133671 Rollins et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Andrew M. Rollins (Cleveland Heights, Ohio);  Christine P. Fleming (Bronx, New York)
ABSTRACT Systems, methods, and other embodiments associated with characterizing Radio Frequency Ablation (RFA) lesions using Optica Coherence Tomography (OCT) are described. One example method includes acquiring an OCT signal from a Region Of Interest (ROI) in an ablated material. The example method may also include determining whether a lesion was formed by the ablation by analyzing optical properties of the ROI as recorded in the OCT signal.
FILED Monday, January 31, 2022
APPL NO 17/589222
ART UNIT 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0066 (20130101)
A61B 5/6852 (20130101)
A61B 18/02 (20130101)
A61B 18/12 (20130101) Original (OR) Class
A61B 18/20 (20130101)
A61B 18/1492 (20130101)
A61B 2017/00243 (20130101)
A61B 2018/00351 (20130101)
A61B 2018/00702 (20130101)
A61B 2090/3735 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133714 Ben-Yakar et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
ASSIGNEE(S) BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas)
INVENTOR(S) Adela Ben-Yakar (Austin, Texas);  Tianqi Li (Poway, California);  Chris Martin (Austin, Texas);  Peisen Zhao (Austin, Texas)
ABSTRACT Systems and methods for line excitation array detection (LEAD) microscopy. The systems and methods include an excitation beam from an optical beam source and a subject of interest. Light is scanned across the subject of interest and optical signals are detected using a parallel optical detection means. A number of mechanical, acoustic and/or optical components such as scanning mirrors, DMDs, OADs, electric motors may be used separately or in conjunction to aid in the scanning of the excitation beam across the subject of interest.
FILED Friday, May 10, 2019
APPL NO 17/054266
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/0071 (20130101) Original (OR) Class
A61B 5/0082 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6458 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/006 (20130101)
G02B 21/0036 (20130101)
G02B 21/0048 (20130101)
G02B 21/0072 (20130101)
G02B 21/0076 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133728 Chevillet et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) University of Washington (Seattle, Washington);  Fred Hutchinson Cancer Research Center (Seattle, Washington)
ASSIGNEE(S) UNIVERSITY OF WASHINGTON (Seattle, Washington);  FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington)
INVENTOR(S) John R. Chevillet (Seattle, Washington);  Tatiana D. Khokhlova (Seattle, Washington);  George R. Schade (Seattle, Washington);  Joo Ha Hwang (Bellevue, Washington);  Muneesh Tewari (Seattle, Washington)
ABSTRACT The present disclosure is directed to relates to systems and methods for evaluating tissue using high intensity focused ultrasound (HIFU) energy. In one embodiment, for example, a system for treating a patient comprises an ultrasound source configured to deliver HIFU energy to a target tissue mass of the patient and a function generator operably coupled to the ultrasound source for initiating a pulsing protocol for delivering the HIFU energy. The system further comprises a controller configured to perform operations comprising applying HIFU energy to induce cavitation in the target tissue mass and cause a biomarker to be released, comparing a baseline concentration of the biomarker from a first fluid sample to a concentration of the biomarker in a second fluid sample within 2 hours after applying HIFU, and repeating the applying and comparing until the concentration of the biomarker in the fluid sample falls below a threshold value.
FILED Friday, January 06, 2023
APPL NO 18/094206
ART UNIT 3797 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/15 (20130101)
A61B 5/145 (20130101)
A61B 5/4836 (20130101)
A61B 5/14507 (20130101)
A61B 5/14546 (20130101) Original (OR) Class
A61B 8/08 (20130101)
A61B 8/5223 (20130101)
A61B 10/007 (20130101)
A61B 10/0038 (20130101)
A61B 2010/0077 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 7/02 (20130101)
A61N 7/022 (20130101)

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6886 (20130101)
C12Q 2600/118 (20130101)
C12Q 2600/158 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133762 Klingensmith et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Board of Trustees of Southern Illinois University (Edwardsville, Illinois)
ASSIGNEE(S) Board of Trustees of Southern Illinois University (Edwardsville, Illinois)
INVENTOR(S) Jon Klingensmith (Carbondale, Illinois);  Colin Gibbons (Glen Carbon, Illinois);  Michaela Kulasekara (Glen Carbon, Illinois);  Vu Quang Dinh (Edwardsville, Illinois)
ABSTRACT A system for patient cardiac imaging and tissue modeling. The system includes a patient imaging device that can acquire patient cardiac imaging data. A processor is configured to receive the cardiac imaging data. A user interface and display allow a user to interact with the cardiac imaging data. The processor includes fat identification software conducting operations to interact with a trained learning network to identify fat tissue in the cardiac imaging data and to map fat tissue onto a three-dimensional model of the heart. A preferred system uses an ultrasound imaging device as the patient imaging device. Another preferred system uses an MRI or CT image device as the patient imaging device.
FILED Wednesday, April 27, 2022
APPL NO 17/730380
ART UNIT 3798 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 5/7275 (20130101)
A61B 8/085 (20130101) Original (OR) Class
A61B 8/0858 (20130101)
A61B 34/10 (20160201)
A61B 2034/105 (20160201)

Image Data Processing or Generation, in General
G06T 7/0012 (20130101)
G06T 2207/30048 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133811 Lerner et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona)
ASSIGNEE(S) ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona)
INVENTOR(S) Zachary F Lerner (Flagstaff, Arizona);  Grigoriy Orekhov (Flagstaff, Arizona);  Leah Liebelt (Flagstaff, Arizona)
ABSTRACT An assistive ankle foot orthosis is described. The AFO has a tubular vertical member arranged laterally to a user's limb. The member carries a rotational bearing and a rotational element such as a pulley. The pulley is connected to a footplate. The footplate provides joint movement assistance or resistance to the user upon rotation of the pulley. The pulley is coupled to one or more springs that provide counter-rotational resistance to pulley movement, thereby storing, and then returning, rotational force during certain foot movements. The spring can include a leaf spring arranged inside the member, the stiffness of which can be manually, automatically or dynamically adjusted by movement of the device.
FILED Friday, October 29, 2021
APPL NO 17/515300
ART UNIT 3786 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits
A61F 5/0127 (20130101) Original (OR) Class
A61F 2005/0155 (20130101)
A61F 2005/0167 (20130101)
A61F 2005/0179 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133855 Xu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Office of Polar Programs (OPP)
The Office of Polar Programs Antarctic (ANT)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) Qiaobing Xu (Lexington, Massachusetts);  Yamin Li (Somerville, Massachusetts)
ABSTRACT Disclosed are compounds of formula (I) below: wherein each of the variables A, B, X, W, V, R1-R5, and m is defined herein. Also disclosed are pharmaceutical compositions containing a nanocomplex, wherein the nanocomplex is formed of one of the compounds, and a protein, a nucleic acid, or a small molecule; and methods of treating a medical condition with one of the pharmaceutical compositions.
FILED Friday, February 01, 2019
APPL NO 16/966368
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1658 (20130101)
A61K 31/22 (20130101)
A61K 31/575 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133888 Heaton et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Nicholas Scott Heaton (Durham, North Carolina);  Alfred Theodore Harding (Durham, North Carolina);  Brook Elizabeth Heaton (Durham, North Carolina)
ABSTRACT Engineered Influenza polynucleotides, viruses, vaccines, and methods of making and using the same are provided. More specifically, the present inventors have developed replication competent engineered influenza viruses having, for example, a modified segment 4 and/or segment 6 that include at least one additional polynucleotide encoding a heterologous polypeptide.
FILED Monday, January 30, 2023
APPL NO 18/103343
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/12 (20130101)
A61K 39/39 (20130101)
A61K 39/145 (20130101) Original (OR) Class
A61K 2039/5252 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/16 (20180101)

Peptides
C07K 14/00 (20130101)
C07K 14/005 (20130101)
C07K 14/11 (20130101)
C07K 2319/42 (20130101)
C07K 2319/50 (20130101)
C07K 2319/60 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 7/00 (20130101)
C12N 9/2402 (20130101)
C12N 15/86 (20130101)
C12N 2760/16121 (20130101)
C12N 2760/16122 (20130101)
C12N 2760/16134 (20130101)
C12N 2760/16143 (20130101)

Enzymes
C12Y 302/01018 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133892 Bakhoum et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York);  THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire)
ASSIGNEE(S) Memorial Sloan Kettering Cancer Center (New York, New York);  The Trustees of Dartmouth College (Hanover, New Hampshire)
INVENTOR(S) Samuel F. Bakhoum (New York, New York);  Bassem I. Zaki (Hanover, New Hampshire);  Duane A. Compton (Hanover, New Hampshire)
ABSTRACT Disclosed is a method for increasing susceptibility of cancer cells to ionizing radiation by delivering to the cells a radiosensitizing agent that has one of the following properties: (a) it perturbs the process of chromosome segregation thereby increasing chromosome missegregation; or (b) it is an inhibitor of an agent that promotes faithful chromosome segregation induces numeric chromosome instability in said cells and this instability is induced substantially simultaneously with or closely prior to or closely after irradiating the cells. Examples of such radiosensitizing agent include inhibitors of one or more of the following: Kif2b, MCAK, MPS1, Eg5/Kinesin-5 5, Polo-like kinase 4, MCAK, Bub1 and Hec1. Such agents specifically target proteins involved in maintaining or promoting faithful chromosome segregation.
FILED Monday, February 27, 2023
APPL NO 18/175433
ART UNIT 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 41/0038 (20130101) Original (OR) Class

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)
A61N 2005/1098 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133893 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
INVENTOR(S) Yunzhi Yang (Stanford, California);  Seyedsina Moeinzadeh (Mountain View, California)
ABSTRACT A stable injectable collagen-based hydrogel delivery platform and method is provided to obtain the viscosity, post-injection stability and mechanical properties needed of an injectable collagen matrix via incorporating alginate and calcium sulfate (CaSO4) into the matrix. The hydrogel (Alg/Col hydrogel) is shear-thinning, injectable through commercially available needles and stable right after injection.
FILED Tuesday, August 24, 2021
APPL NO 17/410554
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/06 (20130101)
A61K 9/0019 (20130101)
A61K 35/28 (20130101)
A61K 47/02 (20130101)
A61K 47/36 (20130101)
A61K 47/42 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133901 Basilion et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) James Basilion (Cleveland, Ohio);  Clemens Burda (Cleveland, Ohio);  Dong Luo (Cleveland, Ohio);  Xinning Wang (Cleveland, Ohio)
ABSTRACT Prostate-specific membrane antigen (PSMA) targeted compounds having formula (I), nanoclusters formed thereof, pharmaceutical compositions comprising a plurality of these compounds, and methods for treating and detecting cancers in a subject are described herein.
FILED Tuesday, January 21, 2020
APPL NO 17/424084
ART UNIT 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/14 (20130101)
A61K 33/242 (20190101)
A61K 41/0038 (20130101)
A61K 47/542 (20170801)
A61K 49/0423 (20130101) Original (OR) Class

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 35/00 (20180101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133924 Cheng et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Board of Regents of The University of Texas System (Austin, Texas)
ASSIGNEE(S) The Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S) Qiang Cheng (Dallas, Texas);  Tuo Wei (Dallas, Texas);  Daniel J. Siegwart (Dallas, Texas)
ABSTRACT The present disclosure provides compositions which shown preferential targeting or delivery of a nucleic acid composition to a particular organ. In some embodiments, the composition comprises a steroid or sterol, an ionizable cationic lipid, a phospholipid, a PEG lipid, and a permanently cationic lipid which may be used to deliver a nucleic acid.
FILED Monday, December 11, 2023
APPL NO 18/534974
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/5123 (20130101) Original (OR) Class
A61K 48/0033 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/22 (20130101)
C12N 15/11 (20130101)
C12N 15/111 (20130101)
C12N 15/113 (20130101)
C12N 2310/11 (20130101)
C12N 2310/14 (20130101)
C12N 2310/20 (20170501)
C12N 2320/32 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133933 Lieberman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Jay R. Lieberman (Los Angeles, California);  William Pannell (Los Angeles, California);  Yong Chen (Los Angeles, California);  Xuan Song (Los Angeles, California);  Sofia Bougioukli (Los Angeles, California)
ABSTRACT Disclosed herein are methods of regional gene-therapy with growth-factor transduced cells, in bone graft scenarios. In embodiments, the methods comprise use of 3D printed scaffolds.
FILED Thursday, June 11, 2020
APPL NO 16/899363
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/10 (20130101)
A61L 27/12 (20130101)
A61L 27/54 (20130101)
A61L 27/227 (20130101)
A61L 27/3821 (20130101)
A61L 27/3834 (20130101)
A61L 27/3847 (20130101) Original (OR) Class
A61L 2300/414 (20130101)
A61L 2430/02 (20130101)

Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster
B28B 1/001 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/129 (20170801)
B29C 64/379 (20170801)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2509/02 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/7532 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 40/20 (20200101)
B33Y 70/00 (20141201)
B33Y 80/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133962 Rafiee et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Transmural Systems LLC (Andover, Massachusetts);  The UNITED STATES OF AMERICA, as represented by the Secretary, Dept. of Health and Human Srvcs. (Bethesda, Maryland)
ASSIGNEE(S) Transmural Systems LLC (Andover, Massachusetts);  United States Department of Health and Human Services (Bethesda, Maryland)
INVENTOR(S) Nasser Rafiee (Andover, Massachusetts);  Robert J. Lederman (Bethesda, Maryland);  Toby Rogers (Bethesda, Maryland);  Dursun Korel Yildirim (Bethesda, Maryland);  Mai Le Diep (Andover, Massachusetts);  Koosha Rafiee (Andover, Massachusetts)
ABSTRACT The disclosure provides various embodiments of catheters having articulable ends that can be used for various procedures. Embodiments of methods are also provided that can be performed with catheters in accordance with the present disclosure.
FILED Sunday, September 08, 2019
APPL NO 16/563925
ART UNIT 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 18/12 (20130101)
A61B 2018/00077 (20130101)
A61B 2018/126 (20130101)
A61B 2018/141 (20130101)
A61B 2018/00184 (20130101)
A61B 2018/00279 (20130101)
A61B 2018/00369 (20130101)
A61B 2018/00601 (20130101)
A61B 2018/1213 (20130101)
A61B 2018/1417 (20130101)
A61B 2018/1432 (20130101)

Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor
A61M 25/0105 (20130101)
A61M 25/09025 (20130101) Original (OR) Class
A61M 2025/09133 (20130101)
A61M 2025/09175 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134601 Upadhyay
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
ASSIGNEE(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
INVENTOR(S) Geeta Upadhyay (Washington, District of Columbia)
ABSTRACT The present technology relates to compounds that inhibit human Ly6K and homologs thereof. Also disclosed are methods of using such compounds to: inhibit activity of a Ly6K protein in a cell; decrease migration, colony formation, and/or proliferation of a cell; modulate expression of a gene in a cell, reduce suppression of the immune response to cancer in a subject, decrease tumorigenic growth of a cancer in a subject, and treat or prevent in a subject a disorder mediated by Ly6K protein.
FILED Friday, November 09, 2018
APPL NO 16/762424
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 39/15 (20130101)

Heterocyclic Compounds
C07D 219/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134634 Verkhusha et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Vladislav V. Verkhusha (Bronx, New York);  Olena S. Oliinyk (Helsinki, Finland)
ASSIGNEE(S)
INVENTOR(S) Vladislav V. Verkhusha (Bronx, New York);  Olena S. Oliinyk (Helsinki, Finland)
ABSTRACT This invention provides the nucleic acid molecules encoding novel small monomeric near-infrared fluorescent protein miRFP670nano, variants and derivatives thereof as well as proteins and peptides encoded by these nucleic acids. The invention also relates to derivatives, homologues, or mutants of the specific proteins referenced above as well as fragments of the nucleic acids and the peptides encoded thereby. The invention further relates to host-cells, stable cell lines and transgenic organisms comprising above-referenced nucleic acid molecules. The present invention also refers to methods of making and using small monomeric near-infrared fluorescent proteins derived from cyanobacteriochromes. The presented protein and its derivatives find use in a variety of applications and approaches, including labeling of biomolecules, cells or cell organelles, detecting protein-protein interactions, and generation of genetically encoded fluorescent biosensors.
FILED Tuesday, December 08, 2020
APPL NO 17/115223
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 49/0045 (20130101)

Peptides
C07K 14/405 (20130101) Original (OR) Class

Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes
C12Q 1/6816 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134641 Wilson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The University of Chicago (Chicago, Illinois)
ASSIGNEE(S) The University of Chicago (Chicago, Illinois)
INVENTOR(S) Patrick Wilson (Chicago, Illinois);  Yaoqing Chen (Chicago, Illinois);  Haley L. Dugan (Chicago, Illinois)
ABSTRACT Provided herein are anti-neuraminidase agents useful for neutralization of influenza virus infection, and methods of use and manufacture thereof. In particular, compositions comprising anti-neuraminidase agents (e.g., antibodies) that are cross-reactive with multiple influenza strains are provided, as well as methods of treatment and prevention of influenza infection therewith.
FILED Thursday, June 15, 2023
APPL NO 18/335879
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/42 (20130101)
A61K 45/06 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 31/16 (20180101)

Peptides
C07K 16/1018 (20130101) Original (OR) Class
C07K 2317/76 (20130101)
C07K 2317/92 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134651 Zou
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) The Regents of the University of California (Oakland, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Yimin Zou (La Jolla, California)
ABSTRACT Methods for inhibiting degeneration of a neuron, methods of treating a neurological/neurodegenerative disease, methods of modulating the directional growth of a neuron, and methods of interfering with the interaction of Wnt and Ryk are provided herein. Also provided are isolated anti-Ryk antibodies and antibody fragments that specifically bind to a binding domain of Wnt.
FILED Friday, December 18, 2020
APPL NO 17/127913
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals
A01K 67/0276 (20130101)
A01K 2227/105 (20130101)
A01K 2267/0318 (20130101)
A01K 2267/0356 (20130101)

Preparations for Medical, Dental, or Toilet Purposes
A61K 35/545 (20130101)
A61K 2039/505 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 25/28 (20180101)

Peptides
C07K 16/00 (20130101)
C07K 16/28 (20130101)
C07K 16/2863 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5023 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134657 Wallisch et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Oregon Health and Science University (Portland, Oregon);  Aronora, Inc. (Portland, Oregon)
ASSIGNEE(S) Oregon Health and Science University (Portland, Oregon);  Aronora, Inc. (Portland, Oregon)
INVENTOR(S) Michael Wallisch (Portland, Oregon);  Andras Gruber (Portland, Oregon);  Erik I. Tucker (Portland, Oregon);  Christina U. Lorentz (Portland, Oregon)
ABSTRACT Monoclonal antibodies that bind, such as specifically bind, blood protein factor XII (FXII) are described. The monoclonal antibodies (including antigen-binding fragments thereof) are capable of forming immune complexes with human FXII and inhibiting FXII activity, resulting in safe anti-inflammatory and anti-thrombotic effects.
FILED Wednesday, November 27, 2019
APPL NO 17/297967
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/00 (20130101)
A61K 39/3955 (20130101)
A61K 45/06 (20130101)
A61K 49/0002 (20130101)
A61K 2039/545 (20130101)

Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations
A61P 7/02 (20180101)

Peptides
C07K 16/36 (20130101) Original (OR) Class
C07K 2317/51 (20130101)
C07K 2317/56 (20130101)
C07K 2317/515 (20130101)
C07K 2317/565 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134721 Mazitschek et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) The General Hospital Corporation (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Ralph Mazitschek (Belmont, Massachusetts);  N. Connor Payne (Cambridge, Massachusetts);  Alena Kalyakina (Karlsruhe, Germany)
ABSTRACT The present application provides ligands and fluorescent or luminescent complexes comprising these ligands.
FILED Tuesday, October 22, 2019
APPL NO 17/287236
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Heterocyclic Compounds
C07D 487/18 (20130101)
C07D 519/00 (20130101)

Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium
C07F 5/00 (20130101)

Materials for Miscellaneous Applications, Not Provided for Elsewhere
C09K 11/06 (20130101) Original (OR) Class
C09K 2211/182 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/6428 (20130101)
G01N 33/582 (20130101)
G01N 2021/6439 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134769 Yao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Baylor College of Medicine (Houston, Texas)
ASSIGNEE(S) Baylor College of Medicine (Houston, Texas)
INVENTOR(S) Qizhi Yao (Houston, Texas);  Christian Marin-Muller (League City, Texas);  Changyi Chen (Houston, Texas)
ABSTRACT A novel network of tumorigenic prognostic factors is identified that plays a critical role in advanced pancreatic cancer (PC) pathogenesis. This interactome is interconnected through a central tumor suppressive microRNA, miR-198, which is able to both directly and indirectly modulate expression of the various members of this network to alter the molecular makeup of pancreatic tumors, with important clinical implications. When this tumor signature network is intact, miR-198 expression is reduced and patient survival is dismal; patients with higher miR-198 present an altered tumor signature network, better prognosis and increased survival. Further, according to the present disclosure, MiR-198 replacement reverses tumorigenicity in vitro and in vivo. As such, an embodiment of the disclosure is a method of treating cancer in an individual, comprising the step of increasing the level of active microRNA-198 molecules in the pancreatic cancer tumor cells of the individual by an amount sufficient to cause an improvement in the pancreatic cancer in the individual.
FILED Wednesday, April 21, 2021
APPL NO 17/236851
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)
A61K 31/7088 (20130101)
A61K 31/7088 (20130101)
A61K 31/7105 (20130101)
A61K 31/7105 (20130101)
A61K 45/06 (20130101)
A61K 51/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)
A61K 2300/00 (20130101)

Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy
A61N 5/10 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 15/113 (20130101)
C12N 15/1135 (20130101) Original (OR) Class
C12N 2310/141 (20130101)
C12N 2320/30 (20130101)
C12N 2320/31 (20130101)

Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests
Y10S 977/704 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/13 (20150115)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134772 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Aging (NIA)
APPLICANT(S) Klogenix LLC (Boston, Massachusetts)
ASSIGNEE(S) Advantage Therapeutics, Inc. (Miami, Florida)
INVENTOR(S) Ci-Di Chen (Boston, Massachusetts);  Ella Zeldich (Boston, Massachusetts);  Carmela Abraham (Boston, Massachusetts)
ABSTRACT The present disclosure relates to compositions and methods for modulating gene expression and in particular to compositions and methods for increasing expression of Klotho. In certain examples, the present disclosure provides a method of increasing expression of a Klotho gene in a cell the method comprising administering to the cell a binding molecule that binds to an RNA transcript transcribed from a chromosomal region within or near the Klotho gene, wherein the RNA transcript does not encode a Klotho protein.
FILED Friday, September 06, 2019
APPL NO 17/276320
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/713 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/2402 (20130101)
C12N 15/67 (20130101) Original (OR) Class
C12N 15/113 (20130101)
C12N 2310/14 (20130101)
C12N 2310/113 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135300 Nolan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
INVENTOR(S) Garry P. Nolan (Redwood City, California);  Sean C. Bendall (San Mateo, California);  Robert M. Angelo (Menlo Park, California)
ABSTRACT A method of analyzing a population of cells is disclosed. In certain embodiments, the method includes i) obtaining an array of cells on a substrate, wherein the cells are labeled with one or more mass tags and are separated from one another, ii) measuring, using secondary ion mass spectrometry (SIMS), the abundance of the one or more mass tags at a plurality of locations occupied by the cells, thereby generating, for each individual cell measured, a set of data, and iii) outputting the set of data for each of the cells analyzed. Also provided herein are systems that find use in performing the subject method. In some embodiments, the system is an automated system for analyzing a population of cells using SIMS.
FILED Tuesday, October 06, 2020
APPL NO 17/064311
ART UNIT 1675 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/2258 (20130101) Original (OR) Class
G01N 33/4833 (20130101)
G01N 33/5005 (20130101)
G01N 33/5008 (20130101)
G01N 33/6848 (20130101)
G01N 2458/15 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/14 (20130101)
H01J 49/0036 (20130101)
H01J 49/142 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135331 Smith
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Vanderbilt University (Nashville, Tennessee)
ASSIGNEE(S) VANDERBILT UNIVERSITY (Nashville, Tennessee)
INVENTOR(S) Scott A. Smith (White Bluff, Tennessee)
ABSTRACT The present disclosure is directed to human monoclonal IgE antibodies, and IgG antibodies engineered therefrom. Such engineered antibodies can be used to blunt pathologic IgE responses in subjects, such as in the treatment or prevention of allergies.
FILED Friday, December 18, 2020
APPL NO 17/127953
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/35 (20130101)
A61K 45/06 (20130101)

Peptides
C07K 16/16 (20130101)
C07K 16/18 (20130101)
C07K 2317/21 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/686 (20130101) Original (OR) Class
G01N 33/5308 (20130101)
G01N 2333/43526 (20130101)
G01N 2333/43582 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135332 Yang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Case Western Reserve University (Cleveland, Ohio)
ASSIGNEE(S) CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio)
INVENTOR(S) Sichun Yang (Solon, Ohio);  Yi Peng (Cleveland, Ohio)
ABSTRACT One aspect of the present disclosure relates to an isolated mutant human estrogen receptor alpha (hERα) that may be used in methods of drug discovery. The isolated mutant hERα can include a DNA-binding domain (DBD), a ligand-binding domain (LBD), and an interface between the DBD and the LBD, wherein at least one tryptophan residue is mutated to a phenylalanine residue.
FILED Tuesday, November 26, 2019
APPL NO 16/695487
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Peptides
C07K 14/525 (20130101)
C07K 14/4748 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/94 (20130101) Original (OR) Class
G01N 33/566 (20130101)
G01N 33/5748 (20130101)
G01N 2500/04 (20130101)
G01N 2500/20 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135337 Franceschini et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Maria A. Franceschini (Winchester, Massachusetts);  Adriano Peruch (Cambridge, Massachusetts);  Kuan Cheng Wu (Boston, Massachusetts);  Marco Renna (Cavallino, Italy)
ABSTRACT A sensor assembly and sensing method is provided for proximity detection for assessing an attachment state of a sensing probe with respect to a subject. A probe is coupled to an electronic probe controller. The probe includes a proximity sensor having a passive energy storing circuit element, and a biological sensor receptacle configured to receive a biological sensor for sensing a biological characteristic of an object. The electronic probe controller excites a circuit network incorporating the proximity sensor with an excitation signal and determines a characteristic of the circuit network that is excited by the excitation signal. The electronic probe controller further generates a proximity indication indicating whether the probe is attached to the object based on the characteristic of the circuit network.
FILED Monday, April 26, 2021
APPL NO 17/240148
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 1/0735 (20130101)
G01R 1/06766 (20130101)
G01R 1/06794 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135411 Cui et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
National Institute of Mental Health (NIMH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Meng Cui (West Lafayette, Indiana);  Hehai Jiang (West Lafayette, Indiana)
ABSTRACT A confocal microscope system includes a light source configured to form a light beam, a scanning unit, and an objective lens. The scanning unit is in the form of a mechanically driven scanning unit with a controllable scanning trajectory, and is configured to direct the light beam through the scanning trajectory. The objective lens defines a pupil plane and a focal plane. The light beam is directed from the scanning unit to the objective lens. The confocal microscope system is configured for multi-color line-scanning confocal microscopy, and implements multi-color fluorescence imaging without laser excitation crosstalk.
FILED Thursday, August 11, 2022
APPL NO 17/885728
ART UNIT 2884 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 13/22 (20130101)
G02B 13/0095 (20130101)
G02B 21/02 (20130101)
G02B 21/008 (20130101)
G02B 21/0032 (20130101) Original (OR) Class
G02B 21/0036 (20130101)
G02B 21/0072 (20130101)
G02B 21/0076 (20130101)
G02B 27/141 (20130101)
G02B 27/1013 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136214 Buckler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ELUCID BIOIMAGING INC. (Boston, Massachusetts)
ASSIGNEE(S) ELUCID BIOIMAGING INC. (Boston, Massachusetts)
INVENTOR(S) Andrew J. Buckler (Boston, Massachusetts);  Kjell Johnson (Ann Arbor, Michigan);  Xiaonan Ma (South Hamilton, Massachusetts);  Keith A. Moulton (Amesbury, Massachusetts);  David S. Paik (Boston, Massachusetts)
ABSTRACT Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
FILED Wednesday, January 17, 2024
APPL NO 18/415125
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 18/24 (20230101)
G06F 18/211 (20230101)
G06F 18/2148 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 3/00 (20130101)
G06T 5/73 (20240101)
G06T 7/11 (20170101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/10048 (20130101)
G06T 2207/10081 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/10101 (20130101)
G06T 2207/10104 (20130101)
G06T 2207/10108 (20130101)
G06T 2207/10132 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/30096 (20130101)
G06T 2207/30104 (20130101)

Image or Video Recognition or Understanding
G06V 10/25 (20220101)
G06V 10/764 (20220101)
G06V 20/69 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136222 Moreau
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Elekta, Inc. (Atlanta, Georgia)
ASSIGNEE(S) Elekta, Inc. (Atlanta, Georgia)
INVENTOR(S) Michel Moreau (Verona, Wisconsin)
ABSTRACT Techniques for contouring of a region of interest based on imaging parameters of spatial imaging data and guided by user input of locations in the spatial imaging data, which may be used for segmentation or radiation treatment planning. An approach of combining a new paint brush tool with an edge-detection algorithm to correct for both the jagged contours and the painting routine not being executed often enough. By using an edge-detection algorithm, the user does not need to focus as much attention on moving the mouse accurately because the system will find the true organ boundary (e.g., using the image gradient) automatically, which may also lead to more time savings.
FILED Monday, April 11, 2022
APPL NO 17/658783
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Image Data Processing or Generation, in General
G06T 7/13 (20170101) Original (OR) Class
G06T 17/205 (20130101)
G06T 2207/10081 (20130101)
G06T 2207/10116 (20130101)
G06T 2207/20104 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136237 Buckland
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Eye Institute (NEI)
APPLICANT(S) Translational Imaging Innovations, Inc. (Hickory, North Carolina)
ASSIGNEE(S) Translational Imaging Innovations, Inc. (Hickory, North Carolina)
INVENTOR(S) Eric L. Buckland (Hickory, North Carolina)
ABSTRACT A model eye for calibrating a retinal imaging system is provided including a backplane having a negative radius of curvature R centered on the optical axis and a clear aperture diameter D2; a distance h along the optical axis from the nodal point to the backplane; an unobstructed field of view 2θ; a closed fluid fillable housing; a mechanical system for mounting, aligning, and preserving spacings of the elements of the model eye; and a pattern applied to the backplane, the pattern having a rotational symmetry and a radial repeating unit, extending substantially across the clear aperture, that spatially modulates intensity of light reflected from, or transmitted through, a surface of the backplane. D2/D1 is greater than 2, an absolute value of R/h is greater than 0.5, and 2θ is greater than zero (0) degrees.
FILED Tuesday, January 04, 2022
APPL NO 17/568306
ART UNIT 2872 — Optics
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 3/12 (20130101)
A61B 3/0025 (20130101)

Image Data Processing or Generation, in General
G06T 3/40 (20130101)
G06T 7/0012 (20130101)
G06T 7/60 (20130101)
G06T 7/80 (20170101) Original (OR) Class
G06T 2207/30041 (20130101)
G06T 2207/30204 (20130101)

Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams
G09B 23/286 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Defense (DOD) 

US 12133846 Qin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Prostate Cancer Research Program (USAMRMCPCRP)
APPLICANT(S) WAYNE STATE UNIVERSITY (Detroit, Michigan)
ASSIGNEE(S) Wayne State University (Detroit, Michigan)
INVENTOR(S) Zhihui Qin (Mundelein, Illinois);  Liping Xu (Detroit, Michigan)
ABSTRACT Isothiocyanate (ITC)-androgen receptor (AR) inhibitor conjugates for apoptosis induction in cancer cells are described. The conjugates can have electrophilicity blocked with an agent such as N-acetyl cysteine. When administered in combination with a glutathione (GSH)-depleting agent, the conjugates result in ferroptosis of cancer cells.
FILED Thursday, October 15, 2020
APPL NO 17/071896
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 31/198 (20130101)
A61K 31/4439 (20130101) Original (OR) Class
A61K 47/54 (20170801)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133855 Xu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Office of Polar Programs (OPP)
The Office of Polar Programs Antarctic (ANT)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) Qiaobing Xu (Lexington, Massachusetts);  Yamin Li (Somerville, Massachusetts)
ABSTRACT Disclosed are compounds of formula (I) below: wherein each of the variables A, B, X, W, V, R1-R5, and m is defined herein. Also disclosed are pharmaceutical compositions containing a nanocomplex, wherein the nanocomplex is formed of one of the compounds, and a protein, a nucleic acid, or a small molecule; and methods of treating a medical condition with one of the pharmaceutical compositions.
FILED Friday, February 01, 2019
APPL NO 16/966368
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1658 (20130101)
A61K 31/22 (20130101)
A61K 31/575 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133997 Wilke
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
Combat Capabilities Development Command (CCDC)
Chemical Biological Center (CCDC CBC)
APPLICANT(S) U.S. Army Combat Capabilities Development Command, Chemical Biological Center (APG, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Douglas E Wilke (Joppa, Maryland)
ABSTRACT A filter adaptor is provided for a respirator that allows the respirator to accommodate filters that have a different connection interface than the filter connection on the respirator. The adaptor includes a body having a first surface and an opposite second surface and defines a through hole. Mask locking tabs on the first surface engage with a complementary bayonet attachment the respirator. A first wall on the first surface and an inlet port gasket thereon nests within a complementary inlet port on the respirator to form an air-tight seal between the first wall and the inlet port. A valve ring on the first surface of the body engages an inlet valve on the respirator. A second wall on the second surface includes filter locking tabs that engage with a complementary filter opening of a filter. A filter gasket around the second wall forms an air-tight seal between the filter opening and the adaptor.
FILED Friday, September 03, 2021
APPL NO 17/466714
ART UNIT 3785 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Devices, Apparatus or Methods for Life-saving
A62B 9/04 (20130101)
A62B 23/02 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134007 Anderson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Michael Anderson (Colorado Springs, Colorado);  Christopher Klinke (Lafayette, Colorado)
ABSTRACT A finger strengthening device (FSD) includes a plurality of finger strengthening elements formed therewith. The FSD is attachable to a structure in a plurality of different orientations to permit a variation in finger exercise techniques.
FILED Monday, October 16, 2023
APPL NO 18/380290
ART UNIT 3784 — Body Treatment, Kinestherapy, and Exercising
CURRENT CPC
Apparatus for Physical Training, Gymnastics, Swimming, Climbing, or Fencing; Ball Games; Training Equipment
A63B 21/4035 (20151001)
A63B 21/4045 (20151001)
A63B 23/16 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134456 Slocum et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Office of the Under Secretary of Defense for Research and Engineering (OUSD R&E)
MIT Lincoln Laboratory (MITLL)
Federally Funded Research and Development Center (FFRDC)
Operated by Massachusetts Institute of Technology (MIT) at Lexington, MA
APPLICANT(S) LTAG SYSTEMS LLC (Bow, New Hampshire)
ASSIGNEE(S) LTAG SYSTEMS LLC (Bow, New Hampshire)
INVENTOR(S) Jonathan T. Slocum (Bow, New Hampshire);  Alexander H. Slocum (Bow, New Hampshire)
ABSTRACT According to one aspect, a system for launching an aerostat may include a reactor defining a chamber, an inflatable structure including a balloon and a neck, the balloon and the neck collectively defining a volume, a coupling defining a passage in fluid communication between the chamber of the reactor and the volume of the inflatable structure, the passage defining a longitudinal axis, and a collar supported on the reactor, the collar defining an orifice in fluid communication between the chamber of the reactor and the passage of the coupling, and the collar releasably restricting displacement of the passage of the coupling, the volume of the inflatable structure, and the chamber of the reactor relative to one another along the longitudinal axis.
FILED Wednesday, February 15, 2023
APPL NO 18/110352
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Lighter-than Air Aircraft
B64B 1/40 (20130101)
B64B 1/58 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134462 Yerant et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Lockheed Martin Corporation (Bethesda, Maryland)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) John Stephen Yerant (Milford, Connecticut);  Timothy Heising Bean (Trumbull, Connecticut);  Stephen V. Poulin (Milford, Connecticut)
ABSTRACT A control input operable by a user for controlling movement of an aircraft includes a base portion configured for coupling to a support surface, the base portion biased towards a neutral position defined along a central axis and pivotable to a plurality of angular positions relative to the central axis. The control input also includes a grip portion having inputs for controlling movement of the aircraft and pivotally coupled to the base portion, the grip portion pivotable between a first position in which the grip portion extends from the base portion and a second position in which the grip portion is pivoted relative to the base portion. Further, the control input includes a lock mechanism for locking the grip portion in the first position wherein releasing the lock mechanism allows the grip portion to move to the second position.
FILED Thursday, October 27, 2022
APPL NO 17/974824
ART UNIT 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeroplanes; Helicopters
B64C 13/14 (20130101) Original (OR) Class
B64C 13/0421 (20180101)
B64C 27/56 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134482 Schlichting
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Grant Sharp Schlichting (Cannon Falls, Minnesota)
ABSTRACT Apparatuses, systems, and methods for towing an aircraft mid-flight are disclosed. The apparatuses include a tow line receiver that is configured for releasably mechanically joining to an aircraft connector on an aircraft to be towed. The aerial vehicle towing system includes an aircraft connector on the aircraft to be towed, a tow line receiver, a tow line, and a winch. Several methods are also provided. These include: a method of towing or retrieving an aircraft in flight; a method of recharging an electrically-powered aircraft in flight; methods of towing and refueling aircraft in flight; a method of communicating between a tow aircraft and an aircraft being towed; and combinations of these methods.
FILED Wednesday, August 31, 2022
APPL NO 17/899846
ART UNIT 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles
B60L 53/00 (20190201)
B60L 2200/10 (20130101)

Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft
B64D 39/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134562 Peterson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia);  South Dakota School of Mines (Rapid City, South Dakota)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia);  South Dakota School of Mines (Rapid City, South Dakota)
INVENTOR(S) G. P. “Bud” Peterson (Atlanta, Georgia);  Haiping Hong (Rapid City, South Dakota)
ABSTRACT Disclosed herein is a method of homogeneously mixing solids, comprising: mixing, in a fluid medium, at least a first nanoparticle material and a surfactant, wherein the surfactant causes the first nanoparticle material to distribute uniformly in the fluid medium and have a specific charge; adding, to the fluid medium, a second nanoparticle material, wherein the surfactant has a charge of opposite polarity to the zeta potential of the second nanoparticle material; attaching the second nanoparticle material to the first nanoparticle material using the charge attraction of the surfactant and the second nanoparticle material to obtain a homogeneous material; and removing the attached first and second nanoparticle materials from the fluid medium to obtain a solid homogeneous material.
FILED Friday, May 10, 2019
APPL NO 17/054202
ART UNIT 1738 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/107 (20220101)
B22F 1/0545 (20220101)
B22F 2301/10 (20130101)
B22F 2301/058 (20130101)
B22F 2301/255 (20130101)
B22F 2302/40 (20130101)
B22F 2998/10 (20130101)
B22F 2999/00 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 40/10 (20200101)
B33Y 70/10 (20200101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/174 (20170801) Original (OR) Class
C01B 2202/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134582 Garnier et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Advanced Ceramic Fibers, LLC (Idaho falls, Idaho)
ASSIGNEE(S) ADVANCED CERAMIC FIBERS, LLC (Idaho Falls, Idaho)
INVENTOR(S) John E. Garnier (Idaho Falls, Idaho);  George W. Griffith (Idaho Falls, Idaho)
ABSTRACT Methods of producing silicon carbide, and other metal carbide materials. The method comprises reacting a carbon material (e.g., fibers, or nanoparticles, such as powder, platelet, foam, nanofiber, nanorod, nanotube, whisker, graphene (e.g., graphite), fullerene, or hydrocarbon) and a metal or metal oxide source material (e.g., in gaseous form) in a reaction chamber at an elevated temperature ranging up to approximately 2400° C. or more, depending on the particular metal or metal oxide, and the desired metal carbide being produced. A partial pressure of oxygen in the reaction chamber is maintained at less than approximately 1.01×102 Pascal, and overall pressure is maintained at approximately 1 atm.
FILED Friday, February 19, 2021
APPL NO 17/179642
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/956 (20170801)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/565 (20130101)
C04B 35/571 (20130101)
C04B 35/573 (20130101)
C04B 35/62281 (20130101) Original (OR) Class
C04B 2235/46 (20130101)
C04B 2235/48 (20130101)
C04B 2235/72 (20130101)
C04B 2235/428 (20130101)
C04B 2235/526 (20130101)
C04B 2235/616 (20130101)
C04B 2235/767 (20130101)
C04B 2235/5244 (20130101)
C04B 2235/5248 (20130101)
C04B 2235/5264 (20130101)
C04B 2235/5284 (20130101)
C04B 2235/5445 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/292 (20150115)
Y10T 428/2918 (20150115)
Y10T 428/2933 (20150115)
Y10T 428/2958 (20150115)
Y10T 428/2964 (20150115)
Y10T 428/2967 (20150115)
Y10T 428/2975 (20150115)
Y10T 428/24993 (20150401)
Y10T 428/249924 (20150401)
Y10T 428/249928 (20150401)
Y10T 428/249974 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134601 Upadhyay
FUNDED BY
Department of Defense (DOD)
Uniformed Services University of the Health Sciences (USUHS)
Henry M Jackson Foundation for the Advancement of Military Medicine, Inc (HJF)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
ASSIGNEE(S) The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland)
INVENTOR(S) Geeta Upadhyay (Washington, District of Columbia)
ABSTRACT The present technology relates to compounds that inhibit human Ly6K and homologs thereof. Also disclosed are methods of using such compounds to: inhibit activity of a Ly6K protein in a cell; decrease migration, colony formation, and/or proliferation of a cell; modulate expression of a gene in a cell, reduce suppression of the immune response to cancer in a subject, decrease tumorigenic growth of a cancer in a subject, and treat or prevent in a subject a disorder mediated by Ly6K protein.
FILED Friday, November 09, 2018
APPL NO 16/762424
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Acyclic or Carbocyclic Compounds
C07C 39/15 (20130101)

Heterocyclic Compounds
C07D 219/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134762 Brown et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Duke University (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) David Brown (Durham, North Carolina);  Gayathri Devi (Durham, North Carolina)
ABSTRACT The present disclosure comprises a lymphovascular bioreactor system and methods of making and using same.
FILED Friday, November 09, 2018
APPL NO 16/762857
ART UNIT 1799 — Organic Chemistry
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/14 (20130101)
C12M 25/04 (20130101)
C12M 35/08 (20130101) Original (OR) Class

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/5017 (20130101)
G01N 33/57415 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134841 Owens, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Nautilus Defense LLC (Pawtucket, Rhode Island)
ASSIGNEE(S) NAUTILUS DEFENSE LLC (Pawtucket, Rhode Island)
INVENTOR(S) James B. Owens, Jr. (Lincoln, Rhode Island);  Zane A. Lewis (Foster, Rhode Island)
ABSTRACT A composite material comprising braided composite yarns that can be embedded within or at the surface of the material. The braided composite yarns can incorporate one or more multicomponent fiber bundles. The braided composite yarns can be the axial yarns in a triaxial braided fabric that has structural yarns as the bias yarns. The composite material can comprise a carbon fiber prepreg. The thickness of each braided composite yarn can be approximately the thickness of a single composite ply. At least one conductive wire can be wrapped around an axial yarn of the braided composite yarn at a location desirable for electrical contact to be made to at least one conductor in the axial yarn. At least some of the conductive wire is preferably soldered to at least one of the conductors. The conductive wire can be twisted with a structural yarn and is stitched across the braided composite yarn. A conductive pad can be soldered to the one conductive wire.
FILED Tuesday, March 22, 2022
APPL NO 17/701360
ART UNIT 3732 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads
D02G 3/12 (20130101)
D02G 3/441 (20130101) Original (OR) Class

Braiding or Manufacture of Lace, Including Bobbin-net or Carbonised Lace; Braiding Machines; Braid; Lace
D04C 1/12 (20130101)

Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles
D10B 2101/12 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134997 Noftz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana);  University of Notre Dame du Lac (South Bend, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana);  University of Notre Dame Du Lac (South Bend, Indiana)
INVENTOR(S) Mark Edward Noftz (Villa Park, Illinois);  Joseph Stephen Jewell (West Lafayette, Indiana);  Andrew James Shuck (Indianapolis, Indiana);  Jonathan Poggie (West Lafayette, Indiana);  Andrew Nixon Bustard (South Bend, Indiana);  Thomas James Juliano (Granger, Indiana)
ABSTRACT Systems and methods capable for use in the development of high-speed, shape-transitioning, inward-turning inlets for air-breathing hypersonic vehicles, and inlets formed thereby. The systems and methods preferably provide for designing high-speed inlets for air-breathing hypersonic vehicles, wherein unique solutions are defined in each osculating plane of the inlet. Such systems and methods optionally provide an optimization process for tuning the post throat-shock Mach number of the inlet, and/or designs a shock-capture surface using a parallel-streamlines methodology, and/or a double cowl-lip geometry to allow flow to spill overboard.
FILED Thursday, August 31, 2023
APPL NO 18/240818
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Jet-propulsion Plants
F02K 7/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135201 Sheng et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) The Texas A and M University System (College Station, Texas)
ASSIGNEE(S) The Texas A and M University System (College Station, Texas)
INVENTOR(S) Jian Sheng (Corpus Christi, Texas);  Maryam Jalali-Mousavi (Woodbury, Minnesota)
ABSTRACT In an embodiment, the present disclosure pertains to a method of performing circulating tumor cell (CTC) analysis. In general, the method includes flowing a sample through a CTC microfluidic platform, deforming a CTC within the sample, measuring CTC deformation through an imprint of the deformed CTC, processing data related to the measuring, and at least one of identifying or characterizing parameters related to the data that enables at least one of detection of CTCs, enumeration of CTCs in the sample, characterization of biophysical properties, CTC cell size, CTC cell membrane deformability, stresses on CTC cell membranes, adhesion stress on CTC cells, normal stress of CTC cells, or combinations thereof. In some embodiments, the flowing includes passing the sample through at least one channel of the CTC microfluidic platform having a constricted section.
FILED Wednesday, April 06, 2022
APPL NO 17/714545
ART UNIT 2877 — Optics
CURRENT CPC
Chemical or Physical Laboratory Apparatus for General Use
B01L 3/502715 (20130101)
B01L 2300/168 (20130101)
B01L 2300/0663 (20130101)

Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours
G01B 11/16 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135240 Jacob et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Navy (DON)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Zubin Jacob (West Lafayette, Indiana);  Fanglin Bao (West Lafayette, Indiana);  Xueji Wang (West Lafayette, Indiana)
ABSTRACT Summary: The invention relates to a temperature sensor, full-A magnetic element (3) that has at least one magnetic Layer (1), its magnetic properties depend on the temperature characterized in that—The magnetic layer (1) has a vortex-shaped magnetization distribution with a magnetic vortex core (2) has, wherein the vortex-shaped magnetization distribution is formed in a layer plane and the vortex core (2) is formed perpendicular to the layer plane,—An excitation unit (15) which is used to excite the vortex-shaped Magnetization distribution to a gyrotropic magnetization motion is provided,—A detection unit (16) for detecting a resonance frequency the gyrotropic magnetization movement is provided and—An evaluation unit (19) for determining a temperature from the resonance frequency of the gyrotropic magnetization movement is provided.
FILED Sunday, December 06, 2020
APPL NO 17/778842
ART UNIT 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry
G01J 3/00 (20130101)
G01J 3/108 (20130101)
G01J 3/447 (20130101)
G01J 3/2823 (20130101) Original (OR) Class
G01J 4/00 (20130101)
G01J 4/04 (20130101)
G01J 5/00 (20130101)
G01J 5/59 (20220101)
G01J 5/485 (20220101)
G01J 2003/2833 (20130101)
G01J 2005/0077 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/21 (20130101)
G01N 21/25 (20130101)
G01N 21/35 (20130101)

Electric Digital Data Processing
G06F 18/22 (20230101)

Image Data Processing or Generation, in General
G06T 2207/10036 (20130101)
G06T 2207/10048 (20130101)

Image or Video Recognition or Understanding
G06V 10/30 (20220101)
G06V 10/40 (20220101)
G06V 10/54 (20220101)
G06V 10/143 (20220101)
G06V 10/751 (20220101)
G06V 10/758 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135254 Adelson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Edward Adelson (Winchester, Massachusetts);  Sandra Liu (Cambridge, Massachusetts)
ABSTRACT A retrographic sensor includes a flexible transparent structure, a transparent elastomeric pad, and an at least partially reflective layer. The flexible transparent structure may be configured to elastically deform between multiple configurations. At least one light source emits light into the transparent structure. The flexible transparent structure may include one or more markers that are illuminated by the at least one light source. The retrographic sensor may also include a photosensitive detector configured to image the flexible transparent structure and one or more markers. A processor may determine a configuration of the flexible transparent structure based at least in part on an image from the one or more markers.
FILED Friday, February 04, 2022
APPL NO 17/665186
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure
G01L 1/24 (20130101) Original (OR) Class
G01L 5/0061 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135300 Nolan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Breast Cancer Research Program (USAMRMCBCRP)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) The Board of Trustees of the Leland Stanford Junior University (Stanford, California)
ASSIGNEE(S) THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California)
INVENTOR(S) Garry P. Nolan (Redwood City, California);  Sean C. Bendall (San Mateo, California);  Robert M. Angelo (Menlo Park, California)
ABSTRACT A method of analyzing a population of cells is disclosed. In certain embodiments, the method includes i) obtaining an array of cells on a substrate, wherein the cells are labeled with one or more mass tags and are separated from one another, ii) measuring, using secondary ion mass spectrometry (SIMS), the abundance of the one or more mass tags at a plurality of locations occupied by the cells, thereby generating, for each individual cell measured, a set of data, and iii) outputting the set of data for each of the cells analyzed. Also provided herein are systems that find use in performing the subject method. In some embodiments, the system is an automated system for analyzing a population of cells using SIMS.
FILED Tuesday, October 06, 2020
APPL NO 17/064311
ART UNIT 1675 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 23/2258 (20130101) Original (OR) Class
G01N 33/4833 (20130101)
G01N 33/5005 (20130101)
G01N 33/5008 (20130101)
G01N 33/6848 (20130101)
G01N 2458/15 (20130101)

Electric Discharge Tubes or Discharge Lamps
H01J 49/14 (20130101)
H01J 49/0036 (20130101)
H01J 49/142 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135433 Rubin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
ASSIGNEE(S) PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts)
INVENTOR(S) Noah A. Rubin (Cambridge, Massachusetts);  Jan Philipp Balthasar Mueller (Cambridge, Massachusetts);  Federico Capasso (Cambridge, Massachusetts)
ABSTRACT An optical component comprises a metasurface comprising nanoscale elements. The metasurface is configured to receive incident light and to generate optical outputs. The geometries and/or orientations of the nanoscale elements provide a first optical output upon receiving a polarized incident light with a first polarization, and provide a second optical output upon receiving a polarized incident light with a second polarization that is different from the first polarization.
FILED Monday, March 13, 2023
APPL NO 18/120958
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 1/002 (20130101)
G02B 5/3083 (20130101)
G02B 27/283 (20130101)
G02B 27/286 (20130101) Original (OR) Class
G02B 2207/101 (20130101)

Holographic Processes or Apparatus
G03H 1/0244 (20130101)
G03H 2222/31 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135635 Fletcher et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Two Six Labs, LLC (Arlington, Virginia)
ASSIGNEE(S) Two Six Labs, LLC (Arlington, Virginia)
INVENTOR(S) Austin Fletcher (Keego Harbor, Michigan);  Daniel Su (Arlington, Virginia);  Bradley Boccuzzi (Arlington, Virginia)
ABSTRACT An automated fault injection testing and analysis approach drives fault injection into a processor driven instruction sequence to quantify and define susceptibility to external fault injections for manipulating instruction execution and control flow of a set of computer instructions. A fault injection such as a voltage or electromagnetic pulse directed at predetermined locations on a processor (Central Processing Unit, or CPU) alters a result of a processor instruction to change values or execution paths. One or more quantified injections define an injection chain that causes a predictable or repeatable deviant result from an expected execution path through the code executed by the processor. Based on accumulation of fault injections and results, a repeatable injection chain and probability identifies an external action taken on a processing device to cause unexpected results that differ from an expected execution of a program or set of computer instructions.
FILED Monday, January 30, 2023
APPL NO 18/102909
ART UNIT 2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electric Digital Data Processing
G06F 11/263 (20130101)
G06F 11/277 (20130101)
G06F 11/3644 (20130101) Original (OR) Class
G06F 11/3692 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135762 Hahn et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia)
ASSIGNEE(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia)
INVENTOR(S) Andrew W. Hahn (Ellicott City, Maryland);  Murali Tummala (Monterey, California);  James Scrofani (Warrenton, Virginia)
ABSTRACT An extended semi-supervised learning (ESSL) generative adversarial network (GAN) including metrics for evaluating training performance and a method for generating an estimated label vector γ by the extended semi-supervised learning (ESSL) generative adversarial network (GAN) discriminator are described. Embodiments in accordance with the invention improve classification accuracy over convolutional neural networks with improved synthetic imagery.
FILED Monday, December 07, 2020
APPL NO 17/113731
ART UNIT 2171 — Graphical User Interface and Document Processing
CURRENT CPC
Electric Digital Data Processing
G06F 18/2132 (20230101) Original (OR) Class
G06F 18/2155 (20230101)
G06F 18/24317 (20230101)

Computer Systems Based on Specific Computational Models
G06N 20/00 (20190101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136197 Newey et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
ASSIGNEE(S) MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts)
INVENTOR(S) Michael Newey (Chelmsford, Massachusetts);  Prafull Sharma (Cambridge, Massachusetts)
ABSTRACT A neural network is used to remove noise from a data signal. The noise removed by the neural network is compared to simulated noise that represents noise expected to be present in the data signal. The results of the comparison are used to train the neural network and improve its ability to remove noise from the data signal.
FILED Friday, November 05, 2021
APPL NO 17/519929
ART UNIT 2672 — Facsimile; Printer; Color; halftone; Scanner; Computer Graphic Processing; 3-D Animation; Display Color; Attributes; Object Processing; Hardware and Memory
CURRENT CPC
Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves
G01S 17/89 (20130101)

Computer Systems Based on Specific Computational Models
G06N 3/045 (20230101)
G06N 3/088 (20130101)

Image Data Processing or Generation, in General
G06T 5/50 (20130101)
G06T 5/70 (20240101) Original (OR) Class
G06T 2207/20081 (20130101)
G06T 2207/20084 (20130101)
G06T 2207/20224 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136680 Song et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) The University of Toledo (Toledo, Ohio)
ASSIGNEE(S) The University of Toledo (Toledo, Ohio)
INVENTOR(S) Zhaoning Song (Toledo, Ohio);  Kamala Khanal Subedi (Toledo, Ohio);  Randy Ellingson (Toledo, Ohio);  Yanfa Yan (Toledo, Ohio)
ABSTRACT An optoelectronic device comprising two photovoltaic absorber materials of CdSeTe and perovskite and their functional component layers that are monolithically integrated into a bifacial tandem solar cell structure.
FILED Thursday, November 18, 2021
APPL NO 17/529682
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/073 (20130101) Original (OR) Class
H01L 31/1884 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136705 Fan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of the Army (DOA)
Aberdeen Proving Ground (APG)
Combat Capabilities Development Command (CCDC)
Night Vision and Electronic Sensors Directorate (NVESD)
APPLICANT(S) American Lithium Energy Corporation (Carlsbad, California)
ASSIGNEE(S) American Lithium Energy Corporation (Carlsbad, California)
INVENTOR(S) Jiang Fan (San Diego, California);  Christopher Kompella (San Diego, California)
ABSTRACT A battery cell may be formed to include a surplus lithium. The surplus lithium may be disposed inside a cavity formed by winding a separator, a positive electrode, and a negative electrode to form a jelly roll of the battery cell. The surplus lithium may be discharged in order to pre-lithiate the battery cell. For example, the surplus lithium may be coupled with the positive electrode and discharged while the battery cell is at least partially charged. Alternatively, the surplus lithium may be coupled with the negative electrode and discharged while the battery cell is at least partially discharged. Moreover, the surplus lithium may be coupled with a negative current collector of the battery cell in order to prevent one or more chemical reactions triggered by an over discharge of the battery cell from corroding the negative current collector of the battery cell.
FILED Thursday, October 17, 2019
APPL NO 16/656277
ART UNIT 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/382 (20130101)
H01M 4/0459 (20130101)
H01M 10/0525 (20130101)
H01M 10/0587 (20130101) Original (OR) Class
H01M 50/117 (20210101)
H01M 50/119 (20210101)
H01M 50/121 (20210101)
H01M 50/124 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136712 Tomar et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Purdue Research Foundation (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Vikas Tomar (West Lafayette, Indiana);  Bing Li (West Lafayette, Indiana);  Vilas G. Pol (West Lafayette, Indiana);  Ryan Andrew Adams (Redwood City, California);  Mihit Hitendra Parekh (West Lafayette, Indiana)
ABSTRACT A method of measuring temperature of a battery having an internally disposed thermal protection arrangement is disclosed which includes providing at least one sensor holder having an electrode side and a housing side disposed within a housing, with at least one cavity provided on the electrode side, providing at least one temperature sensor placed in the at least one cavity of the at least one sensor holder, the outer surface of the at least one temperature sensor being flush with the remaining surface of the at least one sensor holder, attaching the at least one sensor holder to one of a first electrode or a second electrode of the battery, coupling the at least one temperature sensor to a header, and measuring the temperature of the battery.
FILED Tuesday, August 16, 2022
APPL NO 17/889173
ART UNIT 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/382 (20130101)
H01M 4/525 (20130101)
H01M 4/662 (20130101)
H01M 10/486 (20130101) Original (OR) Class
H01M 50/411 (20210101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12137013 Swanson
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) Naval Information Warfare Center Pacific (San Diego, California)
ASSIGNEE(S)
INVENTOR(S) Paul David Swanson (Santee, California)
ABSTRACT A method for demodulating an RF signal to polar in-phase and quadrature (IQ) components that includes converting an RF signal with an analog-to-digital converter and calculating the polar in-phase and quadrature (IQ) components of the RF signal as an IQ phasor phase angle and an IQ amplitude using a digital processor. The analog-to-digital converter uses a sampling rate, where, when the sampling rate used has sampling rates other than 3 times an RF carrier frequency of the RF signal, a digital logic circuit splines data to the sampling rate of 3 times the RF carrier frequency of the RF signal. The digital processor calculates the polar in-phase and quadrature (IQ) components of the RF signal as an IQ phasor phase angle and an IQ amplitude using addition, subtraction, multiplication, division, and absolute value.
FILED Wednesday, January 12, 2022
APPL NO 17/574319
ART UNIT 2633 — Digital Communications
CURRENT CPC
Coding; Decoding; Code Conversion in General
H03M 1/124 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/22 (20130101) Original (OR) Class
H04L 27/3881 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12137064 Tablewski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Information Warfare Center (NIWC)
Naval Information Warfare Center Pacific (NIWCPACIFIC)
APPLICANT(S) The United States of America, as represented by the Secretary of the Navy (San Diego, California)
ASSIGNEE(S) United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Lynne A. Tablewski (San Diego, California);  John Clark Stastny (San Diego, California);  Sparta Cheung (San Diego, California);  Vladimir Y. Matveyev (San Diego, California);  Bryan David Bagnall (Menlo Park, California)
ABSTRACT A communication terminal for addressed messaging within an Automated Identification System (AIS) arrangement includes a user interface and an Aid to Navigation (AtoN) transponder. The user interface facilitates the addressed messaging, which includes one or more of: chat messaging addressed between the communication terminal and a participant terminal of the AIS arrangement, automatic position messaging addressed from the communication terminal to a monitoring terminal of the AIS arrangement, or situational report messaging addressed from the communication terminal to a situational awareness terminal of the AIS arrangement. The AtoN transponder of the communication terminal of the AIS arrangement is coupled to the user interface for transmitting and receiving that achieves the addressed messaging. For the situational report messaging, the situational awareness terminal reformats and exchanges the addressed messaging with a web-based situational awareness tool via the internet.
FILED Wednesday, August 24, 2022
APPL NO 17/894987
ART UNIT 2415 — Multiplex and VoIP
CURRENT CPC
Secret Communication; Jamming of Communication
H04K 1/00 (20130101)

Transmission of Digital Information, e.g Telegraphic Communication
H04L 5/0044 (20130101) Original (OR) Class
H04L 5/0055 (20130101)
H04L 63/1475 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12137310 Girton et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
ASSIGNEE(S) United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio)
INVENTOR(S) Damon Girton (Terre Haute, Indiana);  Johnathan McAllister (Washington, District of Columbia);  Matthew Scharf (Fairborn, Ohio);  Matthew Seymour (Springboro, Ohio);  Peter Voland (Beavercreek, Ohio);  Matthew Stechschulte (Waynesville, Ohio);  Nathan Stover (Xenia, Ohio);  Stevan Gallegos (Oakwood, Ohio)
ABSTRACT A voice communication relay device for use in combination with a protective face mask having an embedded microphone, a headset, a radio, and a push-to-talk (PTT) device that is connected to a radio. The voice communication relay device includes: a housing; a device speaker associated with the housing; an amplifier in the housing, the amplifier being electrically connected to the device speaker; a circuit board located inside of the housing; and a power source. At least one function of the circuit board is to serve as an Impedance dependent auto switch (IDAS) that is electrically connected to the device speaker and an output connector for selectively sending signals to the device speaker or to a radio that is connected to the PTT device.
FILED Thursday, June 30, 2022
APPL NO 17/854002
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Devices, Apparatus or Methods for Life-saving
A62B 18/08 (20130101)

Transmission
H04B 1/385 (20130101)

Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems
H04R 1/083 (20130101) Original (OR) Class
H04R 1/1041 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 12133937 Arinder et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Graham Burton Arinder (Los Alamos, New Mexico);  Joshua Scott Bort (Los Alamos, New Mexico);  Eric Richard Olivas (Los Alamos, New Mexico);  John David Bernardin (Los Alamos, New Mexico)
ABSTRACT Examples of air treatment systems for use in neutralizing airborne pathogens are disclosed herein. The air treatment systems comprise a housing, an air moving device, and one or more sources of ultraviolet light. An airflow may be directed through the enclosure by the air moving device and exposed to the ultraviolet light sources disposed within the enclosure. In some examples, the air treatment systems include one or more baffles disposed within the enclosure to disrupt the linear flow of air through the enclosure and cause more uniform exposure to the ultraviolet light emitted by the sources of ultraviolet light. Some examples may also include one or more air filters for removing particulate matter.
FILED Friday, October 01, 2021
APPL NO 17/492415
ART UNIT 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 9/20 (20130101) Original (OR) Class
A61L 2209/14 (20130101)
A61L 2209/16 (20130101)
A61L 2209/134 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134164 Kasman et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Argonne National Laboratory (ANL)
Federally Funded Research and Development Center (FFRDC)
Operated by UChicago Argonne, LLC (UCHICAGO) at Argonne, IL
APPLICANT(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
ASSIGNEE(S) UCHICAGO ARGONNE, LLC (Chicago, Illinois)
INVENTOR(S) Elina Kasman (Naperville, Illinois);  Jonathan Montgomery (Naperville, Illinois)
ABSTRACT A device for polishing of a multi-surface workpiece is described. The device includes a base and a vertical motion platform that moves along two support rods, which carries a motor that drives a rotating shaft. The support rods extend from said base. A polishing tool is attached to the motor shaft. The workpiece being polished is placed on a linear motion stage during the polishing process.
FILED Wednesday, June 10, 2020
APPL NO 16/897426
ART UNIT 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Machines, Devices, or Processes for Grinding or Polishing; Dressing or Conditioning of Abrading Surfaces; Feeding of Grinding, Polishing, or Lapping Agents
B24B 1/00 (20130101)
B24B 7/02 (20130101)
B24B 7/075 (20130101)
B24B 37/04 (20130101)
B24B 37/013 (20130101)
B24B 37/015 (20130101)
B24B 37/34 (20130101)
B24B 37/042 (20130101)
B24B 37/345 (20130101)
B24B 41/00 (20130101)
B24B 41/005 (20130101)
B24B 41/068 (20130101)
B24B 49/04 (20130101)
B24B 49/12 (20130101)
B24B 51/00 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134582 Garnier et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Advanced Ceramic Fibers, LLC (Idaho falls, Idaho)
ASSIGNEE(S) ADVANCED CERAMIC FIBERS, LLC (Idaho Falls, Idaho)
INVENTOR(S) John E. Garnier (Idaho Falls, Idaho);  George W. Griffith (Idaho Falls, Idaho)
ABSTRACT Methods of producing silicon carbide, and other metal carbide materials. The method comprises reacting a carbon material (e.g., fibers, or nanoparticles, such as powder, platelet, foam, nanofiber, nanorod, nanotube, whisker, graphene (e.g., graphite), fullerene, or hydrocarbon) and a metal or metal oxide source material (e.g., in gaseous form) in a reaction chamber at an elevated temperature ranging up to approximately 2400° C. or more, depending on the particular metal or metal oxide, and the desired metal carbide being produced. A partial pressure of oxygen in the reaction chamber is maintained at less than approximately 1.01×102 Pascal, and overall pressure is maintained at approximately 1 atm.
FILED Friday, February 19, 2021
APPL NO 17/179642
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/956 (20170801)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/565 (20130101)
C04B 35/571 (20130101)
C04B 35/573 (20130101)
C04B 35/62281 (20130101) Original (OR) Class
C04B 2235/46 (20130101)
C04B 2235/48 (20130101)
C04B 2235/72 (20130101)
C04B 2235/428 (20130101)
C04B 2235/526 (20130101)
C04B 2235/616 (20130101)
C04B 2235/767 (20130101)
C04B 2235/5244 (20130101)
C04B 2235/5248 (20130101)
C04B 2235/5264 (20130101)
C04B 2235/5284 (20130101)
C04B 2235/5445 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/292 (20150115)
Y10T 428/2918 (20150115)
Y10T 428/2933 (20150115)
Y10T 428/2958 (20150115)
Y10T 428/2964 (20150115)
Y10T 428/2967 (20150115)
Y10T 428/2975 (20150115)
Y10T 428/24993 (20150401)
Y10T 428/249924 (20150401)
Y10T 428/249928 (20150401)
Y10T 428/249974 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134704 Zhu et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Cheng Zhu (Livermore, California);  Eric Duoss (Dublin, California);  Christopher Spadaccini (Oakland, California);  Marcus A. Worsley (Hayward, California);  Jianchao Ye (Tracy, California);  Swetha Chandrasekaran (Dublin, California)
ABSTRACT An aerogel includes a three-dimensional printed structure having printed ligaments geometrically arranged, where an average diameter of the printed ligaments is in a range of greater than 0 microns and less than 50 microns. In addition, an average distance between a center of a first of the printed ligaments and a center of a second of the printed ligaments is at least equal to the average diameter of the printed ligaments, where the first and the second of the printed ligaments are adjacent. Each printed ligament includes of a plurality of random pores, where an average diameter of the random pores is less than 50 nanometers.
FILED Friday, December 01, 2023
APPL NO 18/527021
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/22 (20130101)
C08K 3/042 (20170501)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/03 (20130101)
C09D 11/38 (20130101) Original (OR) Class
C09D 11/103 (20130101)
C09D 11/324 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134763 Abbas et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Archer-Daniels-Midland Company (Decatur, Illinois)
ASSIGNEE(S) ARCHER-DANIELS-MIDLAND COMPANY (Decatur, Illinois)
INVENTOR(S) Charles Abbas (Champaign, Illinois);  Dan Fanselow (White Bear Lake, Minnesota)
ABSTRACT The present invention is directed to a system and method for producing an organic compound using fermentation wherein multiple components of the system are recycled within the system. The system and method allow for extraction of a high concentration of the organic compound from the fermentation broth in a continuous system that allows recycling of the biomass, aqueous fermentation broth and extraction solvents. The system and method are particularly well adapted for producing and extracting ethanol.
FILED Thursday, July 16, 2020
APPL NO 16/930607
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Apparatus for Enzymology or Microbiology;
C12M 23/44 (20130101)
C12M 29/14 (20130101)
C12M 29/18 (20130101)
C12M 33/12 (20130101)
C12M 33/14 (20130101)
C12M 41/34 (20130101)
C12M 47/10 (20130101) Original (OR) Class
C12M 47/12 (20130101)

Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture
C12P 7/06 (20130101)
C12P 7/14 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 50/10 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134804 Ott et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
Office of Science (DOE-SC)
Ames Laboratory (AL)
Federally Funded Research and Development Center (FFRDC)
Operated by Iowa State University (IASTATE) at Ames, IA
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa);  UT-Battelle, LLC (Oak Ridge, Tennessee);  University of Tennessee Research Foundation (Knoxville, Tennessee);  Fok Industries, Inc. (Manitowoc, Wisconsin);  Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Iowa State University Research Foundation, Inc. (Ames, Iowa);  Lawrence Livermore, National Security, LLC (Livermore, California)
INVENTOR(S) Ryan T. Ott (Ames, Iowa);  Orlando Rios (Oak Ridge, Tennessee);  Zachary C. Sims (Knoxville, Tennessee);  David Weiss (Manitowoc, Wisconsin);  Michael G. Kesler (Oak Ridge, Tennessee);  Fanqiang Meng (Zhuhai, China PRC);  Scott K. McCall (Livermore, California);  Hunter B. Henderson (Livermore, California)
ABSTRACT Production of a bulk Al-RE alloy body (product) using cast billets/ingots (cooling rates <100 C/s) or rapidly solidified Al-RE particulates (cooling rates 102-106° C./second) that have beneficial microstructural refinements that are further refined by subsequent consolidation to produce a consolidated bulk alloy product having excellent mechanical properties over a wide temperature range such as up to and above 230° C.
FILED Tuesday, May 24, 2022
APPL NO 17/803369
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Manufacture of Metal Sheets, Wire, Rods, Tubes or Profiles, Otherwise Than by Rolling; Auxiliary Operations Used in Connection With Metal-working Without Essentially Removing Material
B21C 23/01 (20130101)
B21C 23/14 (20130101)
B21C 29/02 (20130101)
B21C 29/003 (20130101)
B21C 31/00 (20130101)

Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 3/12 (20130101)
B22F 3/20 (20130101)
B22F 2009/0824 (20130101)

Alloys
C22C 1/026 (20130101)
C22C 1/0416 (20130101)
C22C 21/00 (20130101) Original (OR) Class

Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys
C22F 1/04 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134962 Sheng
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
APPLICANT(S) Texas Tech University System (Lubbock, Texas)
ASSIGNEE(S) Texas Tech University System (Lubbock, Texas)
INVENTOR(S) James J. Sheng (Lubbock, Texas)
ABSTRACT Methods for optimization of liquid oil production by huff-n-puff in shale reservoirs to achieve an improved (and optimal) oil recovery factor. The process determines and utilizes the optimum huff and puff times, number of cycles and soaking time under practical operation and reservoir conditions. The huff time in the process is a period so long that the pressure near the wellbore reaches the set maximum injection pressure during the huff period. The puff time in the process is the time required for the pressure near the wellbore to reach the set minimum production pressure during the puff period. Soaking is typically not necessary during the huff-n-puff gas injection in shale oil reservoirs. The number of huff-n-puff cycles is determinable by the time in which the economic rate cut-off is reached.
FILED Monday, May 15, 2023
APPL NO 18/317621
ART UNIT 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells
E21B 43/168 (20130101) Original (OR) Class
E21B 47/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135266 McDaniel et al.
FUNDED BY
Department of Energy (DOE)
Office of Environmental Management (DOE-EM)
Savannah River National Laboratory (SRNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Savannah River Nuclear Solutions, LLC (SRNS) at Aiken, SC
APPLICANT(S) The Florida International University Board of Trustees (Miami, Florida);  Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
ASSIGNEE(S) The Florida International University Board of Trustees (Miami, Florida);  Savannah River Nuclear Solutions, LLC (Aiken, South Carolina)
INVENTOR(S) Dwayne E. McDaniel (Miami, Florida);  Ahmadreza Abbasi Baharanchi (Miami, Florida);  Michael Poirier (Aiken, South Carolina);  Shervin Tashakori (Miami, Florida)
ABSTRACT Systems and methods for determining the yield stress of a non-Newtonian fluid in real time are provided. A pressure loss and/or liquid rise technique, an ultrasonic technique, and/or a penetrometer technique can be used to determine the yield stress of a non-Newtonian fluid. The ultrasonic technique can include a longitudinal wave approach and/or a shear wave approach. The methods and systems are non-invasive and only require slight modifications to the piping containing the non-Newtonian fluid in order to measure the yield stress.
FILED Tuesday, March 08, 2022
APPL NO 17/654006
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 11/08 (20130101) Original (OR) Class
G01N 2011/0033 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135279 Terracciano et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
ASSIGNEE(S) University of Central Florida Research Foundation, Inc. (Orlando, Florida)
INVENTOR(S) Anthony C. Terracciano (Orlando, Florida);  Subith S. Vasu (Orlando, Florida);  Francisco J. Gonzalez (Orlando, Florida)
ABSTRACT A high-altitude atmospheric sensor may include a frame configured to attach to a body of an aircraft, where the frame defines an open measurement cavity for air to travel through during flight of the aircraft. The sensor may further include one or more light sources providing input light such as mid-infrared quantum cascade lasers, a beamsplitter to separate the input light into measurement light propagating along a measurement path and reference light propagating along a reference path, one or more measurement cells providing optical paths for the measurement light in the open measurement cavity of the frame, one or more detectors to capture the measurement light from the one or more measurement cells and the reference light, and a controller to generate one or more spectroscopy measurements of air passing through the open measurement cavity during the flight of the aircraft.
FILED Thursday, November 03, 2022
APPL NO 17/980379
ART UNIT 2877 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/255 (20130101)
G01N 21/3504 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135288 Demos et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
APPLICANT(S) UNIVERSITY OF ROCHESTER (Rochester, New York)
ASSIGNEE(S) University of Rochester (Rochester, New York)
INVENTOR(S) Stavros G. Demos (Pittsford, New York);  Chi Huang (Foster City, California)
ABSTRACT Microscopy with Ultraviolet Surface Excitation (MUSE) for use in the classroom to enhance life sciences education and curricula, or for other applications, including without limitation the operating room, other medical environments, research environments, and low resource environments. MUSE's suitability is based on multiple key factors including its simplicity of use, the incorporation of inexpensive hardware including LED illumination, and very basic tissue preparation. The ultraviolet excitation acts as passive optical sectioning confining the generated fluorescence signal to only a few micrometers below the tissue surface thus eliminating the out of focus signals. This facilitates image capture of tissue microstructure and organization from specimens at the intact or sliced surface arising from varying fluorophore concentration within the different cellular compartments. Although just the tissue auto fluorescence maybe used, image quality is enhanced with brief application of nontoxic fluorescent dyes to selectively highlight cellular compartments. Sample preparation is safe, efficient and familiar to students with basic chemistry or biology lab experience. Mixed-dye powders may be used to simplify translation of this method for educational, medical, research, low resource, and other settings.
FILED Tuesday, November 21, 2023
APPL NO 18/515408
ART UNIT 2884 — Optics
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 1/30 (20130101)
G01N 21/6458 (20130101) Original (OR) Class
G01N 2001/302 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135319 Hanson et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Environmental Biology (DEB)
APPLICANT(S) David Hanson (Albuquerque, New Mexico);  Patrick Joseph Hudson (Albuquerque, New Mexico);  Kaitlyn Johanna Hughes Read (Albuquerque, New Mexico);  Laura Green (Albuquerque, New Mexico);  Joseph Stinziano (Albuquerque, New Mexico);  Tito Busani (Albuquerque, New Mexico);  Mahmoud Behzadirad (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) David Hanson (Albuquerque, New Mexico);  Patrick Joseph Hudson (Albuquerque, New Mexico);  Kaitlyn Johanna Hughes Read (Albuquerque, New Mexico);  Laura Green (Albuquerque, New Mexico);  Joseph Stinziano (Albuquerque, New Mexico);  Tito Busani (Albuquerque, New Mexico);  Mahmoud Behzadirad (Albuquerque, New Mexico)
ABSTRACT Methods and apparatus for electrical impedance spectroscopy for non-destructive, real-time, tracking of relative water content and stress responses in plants.
FILED Monday, March 30, 2020
APPL NO 17/599085
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering
A01G 7/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/223 (20130101)
G01N 33/0098 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135344 Min et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California)
INVENTOR(S) Liang Min (Pleasanton, California);  Nan Duan (Livermore, California)
ABSTRACT Systems and methods for voltage stability monitoring and active/reactive power support are disclosed herein. In some embodiments, a smart electric meter of an end user in a grid power system can measure the voltage supplied to the end user via the grid power system, and can analyze the voltage data to detect critical voltage characteristics. The critical voltage characteristics may indicate that a voltage collapse event is likely. The smart electric meter can further estimate a voltage stability margin based on the voltage data. If necessary, the smart electric meter can control an electrical power source and/or an electric appliance positioned at or near the end user to increase the voltage stability margin.
FILED Wednesday, August 19, 2020
APPL NO 16/997872
ART UNIT 2119 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Measuring Electric Variables; Measuring Magnetic Variables
G01R 22/063 (20130101) Original (OR) Class

Computer Systems Based on Specific Computational Models
G06N 7/01 (20230101)

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 50/06 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135443 Michel et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Lawrence Livermore National Security, LLC (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Pierre Michel (Oakland, California);  Matthew Reid Edwards (Livermore, California)
ABSTRACT A diffractive optical element, such as a holographic plasma lens, can be made by direction two laser beams so that they overlap in a nonlinear material, to form an interference pattern in the nonlinear material. The interference pattern can modify the index of refraction in the nonlinear material to produce the diffractive optical element. The interference pattern can modify the distribution of plasma for the nonlinear material, which can adjust the index of refraction. A third laser beam can be directed through the diffractive optical element to modify the third laser beam, such as to focus, defocus, or collimate the third laser beam.
FILED Friday, March 12, 2021
APPL NO 17/200688
ART UNIT 2872 — Optics
CURRENT CPC
Optical Elements, Systems, or Apparatus
G02B 5/1857 (20130101) Original (OR) Class

Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters
G02F 1/355 (20130101)

Holographic Processes or Apparatus
G03H 1/0402 (20130101)
G03H 1/0465 (20130101)
G03H 2001/0439 (20130101)
G03H 2222/45 (20130101)
G03H 2224/00 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135569 De Oliveira Vivi et al.
FUNDED BY
Department of Energy (DOE)
Collaboration of Oak Ridge, Argonne, and Livermore (CORAL)
APPLICANT(S) Intel Corporation (Santa Clara, California)
ASSIGNEE(S) INTEL CORPORATION (Santa Clara, California)
INVENTOR(S) Rodrigo De Oliveira Vivi (Hillsboro, Oregon);  John Kelbert (Aptos, California);  David Lombard (Rossmoor, California);  Eric Moret (Beaverton, Oregon);  Mark Luckeroth (Portland, Oregon);  Brad Bittel (Beaverton, Oregon);  Phani Kumar Kandula (Bangalore, India)
ABSTRACT Methods, apparatus, systems, and articles of manufacture to reduce thermal fluctuations in semiconductor processors are disclosed. An apparatus includes a temperature analyzer to determine a current temperature of a processor. The apparatus further includes a controller to provide an idle workload to the processor to execute in response to the current temperature falling below a setback temperature.
FILED Wednesday, December 23, 2020
APPL NO 17/133279
ART UNIT 2119 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements
G05B 15/02 (20130101)

Systems for Controlling or Regulating Non-electric Variables
G05D 23/1917 (20130101) Original (OR) Class

Electric Digital Data Processing
G06F 9/4893 (20130101)
G06F 9/5094 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135923 Urick et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Kansas City National Security Campus (KCNSC)
NNSA Critical Mission Site
Operated by Honeywell Federal Manufacturing and Technologies, LLC (FM&T) at Kansas City, MO
APPLICANT(S) nVariate, Inc. (Austin, Texas)
ASSIGNEE(S) nVariate, Inc. (Austin, Texas)
INVENTOR(S) Benjamin Urick (Roseville, California);  Richard H. Crawford (Austin, Texas);  Daniel L. Keller (Waitsfield, Vermont);  Lisa A. Torres (Austin, Texas)
ABSTRACT Methods and computer systems for methods, computer systems, and computer-readable memory media for determining a warp function. A first watertight spline model of a first object and a set of points and associated metadata from a second object are received. A second watertight spline model of the second object is constructed based on the set of points, the metadata, and the first watertight spline model. A warp function is determined based on a difference between the first watertight spline model and the second watertight spline model. The warp function is a continuous function approximating differences between the first object and the second object. The warp function is stored in a non-transitory computer-readable memory medium.
FILED Thursday, April 11, 2024
APPL NO 18/632827
ART UNIT 2148 — Graphical User Interface and Document Processing
CURRENT CPC
Electric Digital Data Processing
G06F 30/17 (20200101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 17/205 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135925 Lei et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Triad National Security, LLC (Los Alamos, New Mexico)
ASSIGNEE(S) Triad National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Zhou Lei (Los Alamos, New Mexico);  Esteban Rougier (Los Alamos, New Mexico);  Earl E. Knight (Rio Rancho, New Mexico);  Antonio Munjiza (London, United Kingdom)
ABSTRACT Computer-implemented methods can include providing a numerical simulation mesh comprising a plurality of nodes and performing a numerical simulation of a solid material using the mesh and a user-selectable transition threshold associated with a cohesive zone model traction-separation relation. Additional computer-implemented methods can include performing a numerical simulation of a solid material using a numerical simulation mesh comprising a plurality of nodes, wherein the numerical simulation includes a transition threshold associated with a cohesive zone model traction-separation relation, and comparing local material states including a strain state of the mesh to the transition threshold during the performing the numerical simulation to determine whether to dynamically insert cohesive elements in the finite element mesh.
FILED Tuesday, April 14, 2020
APPL NO 16/847949
ART UNIT 2146 — Graphical User Interface and Document Processing
CURRENT CPC
Electric Digital Data Processing
G06F 30/17 (20200101)
G06F 30/23 (20200101) Original (OR) Class
G06F 2111/10 (20200101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136620 Rogers et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Materials Sciences and Engineering Division (MSE)
APPLICANT(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  X-CELEPRINT LIMITED (Cork, Ireland)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  X-Celeprint Limited (Cork, Ireland)
INVENTOR(S) John A. Rogers (Wilmette, Illinois);  Ralph Nuzzo (Champaign, Illinois);  Matthew Meitl (Durham, North Carolina);  Etienne Menard (Durham, North Carolina);  Alfred Baca (Urbana, Illinois);  Michael Motala (Champaign, Illinois);  Jong-Hyun Ahn (Suwon, South Korea);  Sang-Il Park (Savoy, Illinois);  Chang-Jae Yu (Urbana, Illinois);  Heung Cho Ko (Gwangju, South Korea);  Mark Stoykovich (Dover, New Hampshire);  Jongseung Yoon (Urbana, Illinois)
ABSTRACT Provided are optical devices and systems fabricated, at least in part, via printing-based assembly and integration of device components. In specific embodiments the present invention provides light emitting systems, light collecting systems, light sensing systems and photovoltaic systems comprising printable semiconductor elements, including large area, high performance macroelectronic devices. Optical systems of the present invention comprise semiconductor elements assembled, organized and/or integrated with other device components via printing techniques that exhibit performance characteristics and functionality comparable to single crystalline semiconductor based devices fabricated using conventional high temperature processing methods. Optical systems of the present invention have device geometries and configurations, such as form factors, component densities, and component positions, accessed by printing that provide a range of useful device functionalities. Optical systems of the present invention include devices and device arrays exhibiting a range of useful physical and mechanical properties including flexibility, shapeability, conformability and stretchablity.
FILED Wednesday, March 09, 2022
APPL NO 17/690952
ART UNIT 2896 — Printing/Measuring and Testing
CURRENT CPC
Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems
B81C 2201/0185 (20130101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 10/00 (20130101)

Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 21/00 (20130101)
H01L 25/042 (20130101)
H01L 25/50 (20130101) Original (OR) Class
H01L 25/167 (20130101)
H01L 25/0753 (20130101)
H01L 27/124 (20130101)
H01L 27/1214 (20130101)
H01L 27/1285 (20130101)
H01L 27/1292 (20130101)
H01L 27/14627 (20130101)
H01L 27/14636 (20130101)
H01L 27/14643 (20130101)
H01L 29/78603 (20130101)
H01L 29/78681 (20130101)
H01L 31/043 (20141201)
H01L 31/167 (20130101)
H01L 31/0288 (20130101)
H01L 31/0525 (20130101)
H01L 31/0543 (20141201)
H01L 31/0547 (20141201)
H01L 31/0693 (20130101)
H01L 31/0725 (20130101)
H01L 31/1804 (20130101)
H01L 31/1824 (20130101)
H01L 31/1868 (20130101)
H01L 31/1876 (20130101)
H01L 31/1892 (20130101)
H01L 31/02005 (20130101)
H01L 31/02008 (20130101)
H01L 31/02168 (20130101)
H01L 31/02325 (20130101)
H01L 31/02327 (20130101)
H01L 31/03046 (20130101)
H01L 33/005 (20130101)
H01L 33/06 (20130101)
H01L 33/30 (20130101)
H01L 33/52 (20130101)
H01L 33/54 (20130101)
H01L 33/56 (20130101)
H01L 33/58 (20130101)
H01L 33/62 (20130101)
H01L 33/0093 (20200501)
H01L 33/483 (20130101)
H01L 2924/00 (20130101)
H01L 2924/0002 (20130101)
H01L 2924/0002 (20130101)
H01L 2933/005 (20130101)
H01L 2933/0058 (20130101)
H01L 2933/0066 (20130101)
H01L 2933/0091 (20130101)

Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical
H01S 5/021 (20130101)
H01S 5/183 (20130101)
H01S 5/423 (20130101)
H01S 5/02251 (20210101)
H01S 5/3013 (20130101)
H01S 5/34326 (20130101)

Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution
Y02E 10/52 (20130101)
Y02E 10/547 (20130101)

Climate Change Mitigation Technologies in the Production or Processing of Goods
Y02P 70/50 (20151101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136680 Song et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) The University of Toledo (Toledo, Ohio)
ASSIGNEE(S) The University of Toledo (Toledo, Ohio)
INVENTOR(S) Zhaoning Song (Toledo, Ohio);  Kamala Khanal Subedi (Toledo, Ohio);  Randy Ellingson (Toledo, Ohio);  Yanfa Yan (Toledo, Ohio)
ABSTRACT An optoelectronic device comprising two photovoltaic absorber materials of CdSeTe and perovskite and their functional component layers that are monolithically integrated into a bifacial tandem solar cell structure.
FILED Thursday, November 18, 2021
APPL NO 17/529682
ART UNIT 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for
H01L 31/073 (20130101) Original (OR) Class
H01L 31/1884 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136888 Erickson et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
APPLICANT(S) The Regents of the University of Colorado, a body (Denver, Colorado)
ASSIGNEE(S)
INVENTOR(S) Robert Erickson (Boulder, Colorado);  Dragan Maksimovic (Boulder, Colorado);  Vivek Sankaranarayanan (Boulder, Colorado);  Aritra Ghosh (Boulder, Colorado);  Yucheng Gao (Boulder, Colorado)
ABSTRACT A bidirectional composite converter is provided. The bidirectional composite converter can be used with power electronics, such as but not limited to electric vehicles and other applications. In some implementations, for example, the composite converter may be used in a powertrain of an electric vehicle to couple batteries to a high voltage bus of the vehicle to provide power to the motors and to one or more integrated charging ports (e.g., ac grid wired connections or a wireless charging port) for extremely fast charging. In various implementations, the bidirectional converter architecture may comprise one or more dc transformer modules (DCX's) arranged with output port(s) coupled in series at an output port of the composite converter.
FILED Friday, August 16, 2019
APPL NO 17/268776
ART UNIT 2859 — Printing/Measuring and Testing
CURRENT CPC
Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy
H02J 7/02 (20130101)
H02J 2207/20 (20200101)

Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof
H02M 1/007 (20210501)
H02M 1/0054 (20210501)
H02M 3/1582 (20130101)
H02M 3/33573 (20210501)
H02M 3/33584 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12137051 Ros-Giralt et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
APPLICANT(S) Reservoir Labs, Inc. (New York, New York)
ASSIGNEE(S) Reservoir Labs, Inc. (San Diego, California)
INVENTOR(S) Jordi Ros-Giralt (Newport Beach, California);  Noah Amsel (New York, New York);  Sruthi Yellamraju (Germantown, Maryland);  Richard A. Lethin (New York, New York)
ABSTRACT A technique is described for quantifying the effect of a perturbation on a property of a network link or flow, and to manipulate the network based on a quantitative estimation of the perturbation.
FILED Monday, February 22, 2021
APPL NO 17/181862
ART UNIT 2461 — Multiplex and VoIP
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 43/045 (20130101)
H04L 43/0882 (20130101)
H04L 47/12 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 12133638 Sheffield et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) BRIGHAM YOUNG UNIVERSITY (Provo, Utah)
ASSIGNEE(S) BRIGHAM YOUNG UNIVERSITY (Provo, Utah)
INVENTOR(S) Jacob L. Sheffield (Provo, Utah);  Amanda Lytle (Provo, Utah);  Jacob G. Hunter (West Lafayette, Indiana);  Lance Hyatt (State College, Pennsylvania);  Larry L. Howell (Orem, Utah)
ABSTRACT A device and methodology for cleaning optical instruments. The device includes a sheath, a wiper mechanism, and an actuator. The sheath attaches to an optical instrument such that the wiper mechanism is in proximity to a lens of the optical instrument. The wiper mechanism includes a blade and a compliant deployment system having first and second curved cross members attached to the blade and sheath such that they bias the blade in a first state where the blade is in a deployed position but can de-form allowing the blade to transition to a second state in a stored position. The actuator maintains tension on the blade to keep the blade in the second state and when the actuator releases tension on blade spring energy stored by the deformation of the curved cross members is released transitioning the blade to the first deployed position providing a wipe of the wiper mechanism.
FILED Tuesday, June 01, 2021
APPL NO 18/000804
ART UNIT 1714 — Coating, Etching, Cleaning, Single Crystal Growth
CURRENT CPC
Diagnosis; Surgery; Identification
A61B 1/126 (20130101) Original (OR) Class
A61B 90/70 (20160201)
A61B 2090/701 (20160201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133855 Xu et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Advancing Translational Sciences (NCATS)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Office of Polar Programs (OPP)
The Office of Polar Programs Antarctic (ANT)
APPLICANT(S) Trustees of Tufts College (Medford, Massachusetts)
ASSIGNEE(S) Trustees of Tufts College (Medford, Massachusetts)
INVENTOR(S) Qiaobing Xu (Lexington, Massachusetts);  Yamin Li (Somerville, Massachusetts)
ABSTRACT Disclosed are compounds of formula (I) below: wherein each of the variables A, B, X, W, V, R1-R5, and m is defined herein. Also disclosed are pharmaceutical compositions containing a nanocomplex, wherein the nanocomplex is formed of one of the compounds, and a protein, a nucleic acid, or a small molecule; and methods of treating a medical condition with one of the pharmaceutical compositions.
FILED Friday, February 01, 2019
APPL NO 16/966368
ART UNIT 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 9/1658 (20130101)
A61K 31/22 (20130101)
A61K 31/575 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12133933 Lieberman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
National Science Foundation (NSF)
APPLICANT(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
ASSIGNEE(S) UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California)
INVENTOR(S) Jay R. Lieberman (Los Angeles, California);  William Pannell (Los Angeles, California);  Yong Chen (Los Angeles, California);  Xuan Song (Los Angeles, California);  Sofia Bougioukli (Los Angeles, California)
ABSTRACT Disclosed herein are methods of regional gene-therapy with growth-factor transduced cells, in bone graft scenarios. In embodiments, the methods comprise use of 3D printed scaffolds.
FILED Thursday, June 11, 2020
APPL NO 16/899363
ART UNIT 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/10 (20130101)
A61L 27/12 (20130101)
A61L 27/54 (20130101)
A61L 27/227 (20130101)
A61L 27/3821 (20130101)
A61L 27/3834 (20130101)
A61L 27/3847 (20130101) Original (OR) Class
A61L 2300/414 (20130101)
A61L 2430/02 (20130101)

Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster
B28B 1/001 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/129 (20170801)
B29C 64/379 (20170801)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2509/02 (20130101)

Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles
B29L 2031/7532 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 40/20 (20200101)
B33Y 70/00 (20141201)
B33Y 80/00 (20141201)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134702 Yum et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil, Mechanical and Manufacturing Innovation (CMMI)
APPLICANT(S) Board of Regents, The University of Texas System (Austin, Texas)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Kyungsuk Yum (Fort Worth, Texas);  Amirali Nojoomi (Arlington, Texas);  Hakan Arslan (Arlington, Texas)
ABSTRACT In accordance with the purpose(s) of the present disclosure, as embodied and broadly described herein, the disclosure, in one aspect, relates to gel-phase inks suitable for extrusion-based 3D printing and methods of making the same, as well as anisotropic hydrogels printed from the same. In another aspect, the disclosure relates to linear contractile elements constructed from the anisotropic hydrogels and 3D structures with programmed morphologies and motions comprising the linear contractile elements. In still another aspect, the disclosure relates to a process for preparing soft materials and a method to create 3D structures starting from the gel-phase inks disclosed herein. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
FILED Friday, September 11, 2020
APPL NO 17/017907
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles
A61L 27/38 (20130101)
A61L 2430/30 (20130101)

Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing
B29C 64/129 (20170801)

Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts
B29K 2105/0002 (20130101)
B29K 2105/0061 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 10/00 (20141201)
B33Y 70/00 (20141201)

Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor
C09D 11/101 (20130101)
C09D 11/102 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134788 Maeda et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Integrative Organismal Systems (IOS)
APPLICANT(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Hiroshi A. Maeda (Madison, Wisconsin);  Craig Albert Schenck (Madison, Wisconsin)
ABSTRACT The invention generally relates to engineered prephenate dehydrogenases and arogenate dehydrogenases and methods of using the same. More specifically, the invention relates in part to compositions including engineered prephenate dehydrogenases (PDH) polypeptides and engineered arogenate dehydrogenase (ADH) polypeptides with altered substrate preferences and tyrosine sensitivities and methods of using the same.
FILED Monday, August 30, 2021
APPL NO 17/460874
ART UNIT 1662 — Plants
CURRENT CPC
Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 9/001 (20130101) Original (OR) Class
C12N 15/8251 (20130101)

Enzymes
C12Y 103/01012 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135319 Hanson et al.
FUNDED BY
Department of Energy (DOE)
Advanced Research Projects Agency - Energy (ARPA-E)
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Environmental Biology (DEB)
APPLICANT(S) David Hanson (Albuquerque, New Mexico);  Patrick Joseph Hudson (Albuquerque, New Mexico);  Kaitlyn Johanna Hughes Read (Albuquerque, New Mexico);  Laura Green (Albuquerque, New Mexico);  Joseph Stinziano (Albuquerque, New Mexico);  Tito Busani (Albuquerque, New Mexico);  Mahmoud Behzadirad (Albuquerque, New Mexico)
ASSIGNEE(S)
INVENTOR(S) David Hanson (Albuquerque, New Mexico);  Patrick Joseph Hudson (Albuquerque, New Mexico);  Kaitlyn Johanna Hughes Read (Albuquerque, New Mexico);  Laura Green (Albuquerque, New Mexico);  Joseph Stinziano (Albuquerque, New Mexico);  Tito Busani (Albuquerque, New Mexico);  Mahmoud Behzadirad (Albuquerque, New Mexico)
ABSTRACT Methods and apparatus for electrical impedance spectroscopy for non-destructive, real-time, tracking of relative water content and stress responses in plants.
FILED Monday, March 30, 2020
APPL NO 17/599085
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering
A01G 7/00 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 27/223 (20130101)
G01N 33/0098 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136284 Robles et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia)
INVENTOR(S) Francisco E. Robles (Atlanta, Georgia);  Ashkan Ojaghi (Atlanta, Georgia)
ABSTRACT A deep-ultraviolet microscopy system includes a light source for outputting a light beam for illuminating a biological sample, the light beam being inclusive of ultraviolet wavelengths; a reception space for reception of a biological sample for illumination by the light beam; an ultraviolet microscope objective for collecting and relaying light that interacts with the biological sample to an image capture device; and an ultraviolet sensitive image capture device for capturing images of the biological sample, with the microscopy system configured to capture multiple images of the biological sample at one or more ultraviolet wavelengths. A method of processing ultraviolet images of biological samples includes receiving a plurality of multi-spectral ultraviolet images of a biological sample; normalizing and scaling the images; and assigning each image to a channel in the RGB color-space based on wavelength.
FILED Tuesday, October 13, 2020
APPL NO 17/767328
ART UNIT 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 21/33 (20130101)
G01N 33/49 (20130101)
G01N 2201/0621 (20130101)

Optical Elements, Systems, or Apparatus
G02B 21/16 (20130101)
G02B 21/365 (20130101)

Image Data Processing or Generation, in General
G06T 3/40 (20130101)

Image or Video Recognition or Understanding
G06V 10/70 (20220101)
G06V 20/693 (20220101)
G06V 20/695 (20220101)
G06V 20/698 (20220101) Original (OR) Class

Pictorial Communication, e.g Television
H04N 9/64 (20130101)
H04N 23/56 (20230101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136702 Rustomji et al.
FUNDED BY
National Science Foundation (NSF)
Directorate of Geosciences (GEO)
Office of Polar Programs (OPP)
The Office of Polar Programs Antarctic (ANT)
APPLICANT(S) SOUTH 8 TECHNOLOGIES, INC. (San Diego, California)
ASSIGNEE(S) South 8 Technologies, Inc. (San Diego, California)
INVENTOR(S) Cyrus S. Rustomji (San Diego, California);  Jungwoo Lee (San Diego, California);  James Royer (San Diego, California);  Miguel Ceja (Manteca, California)
ABSTRACT A safe electrolyte comprising a liquefied gas solvent that will transition from a liquid state to a gas state (“gas off”) at a pressure of 100 kPa and a temperature of 293.15 K is disclosed. A first mixture is formed from a first electrolyte component (one or more solvents) mixed with a second electrolyte component (one or more hydrocarbon co-solvents). The addition of the second electrolyte component (1) lowers the vapor pressure of the first mixture by at least 10% as compared to the vapor pressure of the first electrolyte component alone, when measured at 293.15 K, and (2) results in a vapor pressure of the first mixture above 100 kPa at a temperature of 293.15 K. The second electrolyte component may also be selected to lower the global warming potential (GWP) of the first mixture by at least 10% as compared to the GWP of the first electrolyte component alone. The safe liquefied gas electrolyte is formed by mixing a third electrolyte component (one or more salts) to the first mixture. This safe liquefied gas electrolyte can then be used to manufacture an electrochemical energy storage device.
FILED Tuesday, October 24, 2023
APPL NO 18/383255
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 10/0567 (20130101) Original (OR) Class
H01M 10/0569 (20130101)
H01M 50/183 (20210101)
H01M 2300/0028 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 12134562 Peterson et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) Georgia Tech Research Corporation (Atlanta, Georgia);  South Dakota School of Mines (Rapid City, South Dakota)
ASSIGNEE(S) Georgia Tech Research Corporation (Atlanta, Georgia);  South Dakota School of Mines (Rapid City, South Dakota)
INVENTOR(S) G. P. “Bud” Peterson (Atlanta, Georgia);  Haiping Hong (Rapid City, South Dakota)
ABSTRACT Disclosed herein is a method of homogeneously mixing solids, comprising: mixing, in a fluid medium, at least a first nanoparticle material and a surfactant, wherein the surfactant causes the first nanoparticle material to distribute uniformly in the fluid medium and have a specific charge; adding, to the fluid medium, a second nanoparticle material, wherein the surfactant has a charge of opposite polarity to the zeta potential of the second nanoparticle material; attaching the second nanoparticle material to the first nanoparticle material using the charge attraction of the surfactant and the second nanoparticle material to obtain a homogeneous material; and removing the attached first and second nanoparticle materials from the fluid medium to obtain a solid homogeneous material.
FILED Friday, May 10, 2019
APPL NO 17/054202
ART UNIT 1738 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder
B22F 1/107 (20220101)
B22F 1/0545 (20220101)
B22F 2301/10 (20130101)
B22F 2301/058 (20130101)
B22F 2301/255 (20130101)
B22F 2302/40 (20130101)
B22F 2998/10 (20130101)
B22F 2999/00 (20130101)

Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering
B33Y 40/10 (20200101)
B33Y 70/10 (20200101)

Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)
B82Y 40/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/174 (20170801) Original (OR) Class
C01B 2202/08 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12135269 Brosius et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
APPLICANT(S) University of Florida Research Foundation, Inc. (Gainesville, Florida);  United States of America As Represented By The Administrator of NASA (Washington, District of Columbia)
ASSIGNEE(S) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida);  UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia)
INVENTOR(S) Nevin B. Brosius (Gainesville, Florida);  Ranganathan Narayanan (Gainesville, Florida);  Michael P. SanSoucie (Huntsville, Alabama)
ABSTRACT Various examples are provided related to measuring surface tension. In one example, a method includes levitating a sample using electrostatic levitation; applying a signal to at least one electrode to excite the sample into a n=3 mode of oscillation; capturing images of the sample with a respective image being associated with a particular frequency that is applied to the sample when the respective image is captured; quantifying sample resonance using a projection method of Legendre polynomials based on the plurality of images; and determining a measured resonance frequency of the sample by an analysis of the sample resonance. The sample can be levitated using a feedback-controlled voltage and the applied signal can be swept over a range of frequencies. A system including electrodes, a position sensor, a camera device, and at least one computing device can be used to carry out the method.
FILED Tuesday, October 19, 2021
APPL NO 17/505224
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 13/02 (20130101) Original (OR) Class
G01N 2013/0225 (20130101)
G01N 2013/0283 (20130101)

Image Data Processing or Generation, in General
G06T 7/62 (20170101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136007 Fink et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) United States of America as represented by the Administrator of NASA (Houston, Texas)
ASSIGNEE(S) United States of America as represented by the Administrator of NASA (Washington, District of Columbia)
INVENTOR(S) Patrick W. Fink (Houston, Texas);  Greg Y. Lin (Houston, Texas);  Phong H. Ngo (Houston, Texas);  David S. Hafermalz (Houston, Texas);  Raymond S. Wagner (Houston, Texas);  Lazaro D. Rodriguez (Houston, Texas)
ABSTRACT A radio-frequency identification (RFID) antenna assembly, per an implementation, includes a number of multiplexer modules coupled with one another. Radio frequency (RF) signals are received from an RFID reader. One or more of the multiplexer modules has a switch with multiple output ports. An antenna connects with one of the output ports and, per an implementation, an encoder connects with another of the output ports. The multiplexer module(s) may also have a first rectifier for rapid self-powering capabilities, and a second rectifier for more robust self-powering capabilities.
FILED Wednesday, July 06, 2022
APPL NO 17/810890
ART UNIT 2876 — Optics
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 19/0701 (20130101)
G06K 19/0724 (20130101) Original (OR) Class
G06K 19/07345 (20130101)

Antennas, i.e Radio Aerials
H01Q 1/2208 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136735 Xu et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Jet Propulsion Laboratory (JPL)
Federally Funded Research and Development Center (FFRDC)
Operated by California Institute of Technology (CALTECH) at Pasadena, CA
APPLICANT(S) HONDA MOTOR CO., LTD. (Tokyo, Japan);  California Institute of Technology (Pasadena, California)
ASSIGNEE(S) HONDA MOTOR CO., LTD. (Tokyo, Japan);  California Institute of Technology (Pasadena, California)
INVENTOR(S) Qingmin Xu (Dublin, Ohio);  Christopher Brooks (Dublin, Ohio);  Ryan McKenney (Roseville, Minnesota);  Thomas Miller, III (South Pasadena, California);  Simon C. Jones (Whittier, California);  Steve Munoz (Pasadena, California);  Victoria Davis (Santa Clarita, California)
ABSTRACT An electrochemically active structure having a core and a shell at least partially surrounding the core. Also a method of making the electrochemically active structure as described herein as well as electrochemical cells comprising the electrochemically active structure as described herein.
FILED Tuesday, June 18, 2019
APPL NO 16/444854
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 40/00 (20130101)

Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds
C08G 63/685 (20130101)

Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients
C08K 3/16 (20130101)
C08K 2201/005 (20130101)

Compositions of Macromolecular Compounds
C08L 67/02 (20130101)
C08L 2207/53 (20130101)

Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy
H01M 4/366 (20130101)
H01M 4/667 (20130101)
H01M 4/5835 (20130101) Original (OR) Class
H01M 10/36 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 12134582 Garnier et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
Department of Energy (DOE)
Office of Nuclear Energy (DOE-NE)
Idaho National Laboratory (INL)
Federally Funded Research and Development Center (FFRDC)
Operated by Battelle Energy Alliance, LLC (BEA) at Idaho Falls, ID
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) Advanced Ceramic Fibers, LLC (Idaho falls, Idaho)
ASSIGNEE(S) ADVANCED CERAMIC FIBERS, LLC (Idaho Falls, Idaho)
INVENTOR(S) John E. Garnier (Idaho Falls, Idaho);  George W. Griffith (Idaho Falls, Idaho)
ABSTRACT Methods of producing silicon carbide, and other metal carbide materials. The method comprises reacting a carbon material (e.g., fibers, or nanoparticles, such as powder, platelet, foam, nanofiber, nanorod, nanotube, whisker, graphene (e.g., graphite), fullerene, or hydrocarbon) and a metal or metal oxide source material (e.g., in gaseous form) in a reaction chamber at an elevated temperature ranging up to approximately 2400° C. or more, depending on the particular metal or metal oxide, and the desired metal carbide being produced. A partial pressure of oxygen in the reaction chamber is maintained at less than approximately 1.01×102 Pascal, and overall pressure is maintained at approximately 1 atm.
FILED Friday, February 19, 2021
APPL NO 17/179642
ART UNIT 1767 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures
B82Y 30/00 (20130101)

Non-metallic Elements; Compounds Thereof;
C01B 32/956 (20170801)

Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone
C04B 35/565 (20130101)
C04B 35/571 (20130101)
C04B 35/573 (20130101)
C04B 35/62281 (20130101) Original (OR) Class
C04B 2235/46 (20130101)
C04B 2235/48 (20130101)
C04B 2235/72 (20130101)
C04B 2235/428 (20130101)
C04B 2235/526 (20130101)
C04B 2235/616 (20130101)
C04B 2235/767 (20130101)
C04B 2235/5244 (20130101)
C04B 2235/5248 (20130101)
C04B 2235/5264 (20130101)
C04B 2235/5284 (20130101)
C04B 2235/5445 (20130101)

Technical Subjects Covered by Former US Classification
Y10T 428/292 (20150115)
Y10T 428/2918 (20150115)
Y10T 428/2933 (20150115)
Y10T 428/2958 (20150115)
Y10T 428/2964 (20150115)
Y10T 428/2967 (20150115)
Y10T 428/2975 (20150115)
Y10T 428/24993 (20150401)
Y10T 428/249924 (20150401)
Y10T 428/249928 (20150401)
Y10T 428/249974 (20150401)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136214 Buckler et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) ELUCID BIOIMAGING INC. (Boston, Massachusetts)
ASSIGNEE(S) ELUCID BIOIMAGING INC. (Boston, Massachusetts)
INVENTOR(S) Andrew J. Buckler (Boston, Massachusetts);  Kjell Johnson (Ann Arbor, Michigan);  Xiaonan Ma (South Hamilton, Massachusetts);  Keith A. Moulton (Amesbury, Massachusetts);  David S. Paik (Boston, Massachusetts)
ABSTRACT Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.
FILED Wednesday, January 17, 2024
APPL NO 18/415125
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Electric Digital Data Processing
G06F 18/24 (20230101)
G06F 18/211 (20230101)
G06F 18/2148 (20230101)

Computer Systems Based on Specific Computational Models
G06N 3/08 (20130101)
G06N 20/00 (20190101)

Image Data Processing or Generation, in General
G06T 3/00 (20130101)
G06T 5/73 (20240101)
G06T 7/11 (20170101)
G06T 7/0012 (20130101) Original (OR) Class
G06T 2207/10048 (20130101)
G06T 2207/10081 (20130101)
G06T 2207/10088 (20130101)
G06T 2207/10101 (20130101)
G06T 2207/10104 (20130101)
G06T 2207/10108 (20130101)
G06T 2207/10132 (20130101)
G06T 2207/20081 (20130101)
G06T 2207/30096 (20130101)
G06T 2207/30104 (20130101)

Image or Video Recognition or Understanding
G06V 10/25 (20220101)
G06V 10/764 (20220101)
G06V 20/69 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136498 Jenkins et al.
FUNDED BY
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) METROLASER, INC. (Laguna Hills, California)
ASSIGNEE(S) METROLASER, INC. (Laguna Hills, California)
INVENTOR(S) Thomas P. Jenkins (Irvine, California);  David Feng (Pleasanton, California);  Jacob George (Downey, California)
ABSTRACT A system for measuring velocities and densities of a particle-free flow of molecules is provided. In various embodiments of the disclosure, the system may include a laser configured to form a two-dimensional light sheet for interrogating a flow of molecules at a measurement region with the two-dimensional light sheet. The system may include a first camera coupled with a first filter and a second camera coupled to a second filter. The cameras can be oriented toward the measurement region at a first angle and a second angle, respectively, with respect to a direction of the two-dimensional light sheet. The cameras are configured to capture images of scattered light from the measurement region through the filters. The two-dimensional spatial distribution of density and velocity values of the flow of molecules can be determined based on the images acquired via the first camera and the second camera.
FILED Thursday, October 12, 2023
APPL NO 18/486076
ART UNIT 2852 — Printing/Measuring and Testing
CURRENT CPC
Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 9/00 (20130101)
G01N 15/0227 (20130101)
G01N 21/4795 (20130101)

Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement
G01P 3/685 (20130101)

Image Data Processing or Generation, in General
G06T 7/292 (20170101)

Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes
G21K 1/10 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 12134090 Kersten et al.
FUNDED BY
Department of Agriculture (USDA)
U.S. Forest Service (FS)
APPLICANT(S) THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia)
ASSIGNEE(S)
INVENTOR(S) Philip J. Kersten (Arena, Wisconsin);  Thomas J. Schwartz (Orono, Maine);  James A. Dumesic (Verona, Wisconsin)
ABSTRACT A method of conducting oxidation in an inflatable bag bioreactor or a batch reactor is provided. The inflatable bag bioreactor or the batch reactor is used as an efficient, economical, and convenient reaction vessel. The inflatable bag bioreactor or batch reactor is rotated or rocked during the reaction to ensure continued exposure of the reaction mixture to the headspace gas in the vessel. The ability of the inflatable bag to expand or contract as the volume of the contents changes helps maintain consistent pressure and avoids the need to replenish the headspace gas.
FILED Thursday, April 22, 2021
APPL NO 17/237618
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus
B01J 8/001 (20130101) Original (OR) Class
B01J 19/0046 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12134673 Cochran et al.
FUNDED BY
Department of Agriculture (USDA)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S) Iowa State University Research Foundation, Inc. (Ames, Iowa)
ASSIGNEE(S) IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa)
INVENTOR(S) Eric W. Cochran (Ames, Iowa);  Xianglan Bai (Ames, Iowa);  Wangda Qu (Ames, Iowa);  Yuerui Huang (Ames, Iowa);  Yixin Luo (Ames, Iowa)
ABSTRACT One aspect of the present application relates to a method of synthesizing a thermoplastic polymer. This method includes providing a depolymerized lignin product comprising monomers and oligomers and producing lignin (meth)acrylate monomers and oligomers from the depolymerized lignin product. A thermoplastic lignin (meth)acrylate polymer is then formed by free radical polymerization of the lignin (meth)acrylate monomers and oligomers. The present application also relates to a branched chain thermoplastic lignin (meth)acrylate polymer which includes a chain transfer agent. The thermoplastic lignin based polymers of the present application can be used to prepare carbon fibers, and engineering thermoplastics. Mixtures of lignin (meth)acrylate monomers and oligomers are also disclosed.
FILED Tuesday, January 16, 2024
APPL NO 18/413501
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Non-metallic Elements; Compounds Thereof;
C01B 32/05 (20170801)

Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds
C08F 293/005 (20130101) Original (OR) Class
C08F 2438/01 (20130101)
C08F 2438/03 (20130101)

Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H
C08J 11/12 (20130101)
C08J 2397/02 (20130101)

Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments
D01F 9/12 (20130101)
D01F 11/122 (20130101)
D01F 11/125 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

United States Postal Service (USPS) 

US 12135219 Turner et al.
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Alison Frankowski Turner (Arlington, Virginia);  Marc D. McCrery (Arlington, Virginia);  James J. Boldt (Leesburg, Virginia)
ABSTRACT A system and method of augmenting a delivery route. Exemplary methods include first location information from a first position device and receiving second location information from a second position device, storing first and second location information, and determining, based on at least one of the first and second information, a time and a location for each of a plurality of stops. Exemplary methods also include reconciling determined time and locations of each of the plurality of stops with a stored route, the stops having a stored location and a stored time associated therewith and estimating a plurality of transition times between pairs of the plurality of stops. Exemplary methods include constructing an updated timeline based on the plurality of stored stops, the plurality of determined stops, and the plurality of transition times and updating the delivery route based on the constructed timeline.
FILED Monday, January 02, 2023
APPL NO 18/149146
ART UNIT 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit
B60W 50/045 (20130101)
B60W 2050/046 (20130101)

Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry
G01C 21/3492 (20130101) Original (OR) Class

Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for
G06Q 10/047 (20130101)
G06Q 10/08355 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 
US 12136017 Simpson
FUNDED BY
United States Postal Service (USPS)
APPLICANT(S) United States Postal Service (Washington, District of Columbia)
ASSIGNEE(S) United States Postal Service (Washington, District of Columbia)
INVENTOR(S) Ryan J. Simpson (Vienna, Virginia)
ABSTRACT The present disclosure relates to a system and method for detecting an address block and barcode on a captured image of an item, and reading the detected barcode using connected component analysis. In one aspect, the method includes binarizing a captured image to generate a binarized image having pixel values, inverting the pixel values of the binarized image, processing the inverted pixel values, and filtering the processed image by area. The method may also include machine learning the processed image to cluster objects in the processed image into a plurality of groups using the filtered image, and determining a number of objects in each of the clustered groups by performing additional operations on the clustered objects to detect the address block. The method may also include selecting the group having the greatest number of objects as the address block, and extracting the selected address block.
FILED Thursday, April 27, 2023
APPL NO 18/308529
ART UNIT 2876 — Optics
CURRENT CPC
Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers
G06K 7/1413 (20130101)
G06K 7/1447 (20130101) Original (OR) Class

Image Data Processing or Generation, in General
G06T 5/20 (20130101)
G06T 7/60 (20130101)
G06T 7/70 (20170101)
G06T 2207/30242 (20130101)

Image or Video Recognition or Understanding
G06V 10/762 (20220101)
G06V 30/10 (20220101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 12134757 Ling et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S) Southwest Research Institute (San Antonio, Texas);  The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania)
ASSIGNEE(S) Southwest Research Institute (San Antonio, Texas);  The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania)
INVENTOR(S) Jian Ling (Spring Branch, Texas);  Kreg A. Zimmern (San Antonio, Texas);  Michael C. Milone (Philadelphia, Pennsylvania)
ABSTRACT Described herein is a beads-free bioprocessor as an automated and cost-effective T cell processing and manufacturing platform. T cells are a core component in CAR T cell therapies for cancer treatment, but are difficult to manufacture to scale in clinically relevant quantities. The 3D bioprocessor provides an alternative device that is scalable, beads-free, easy-to-use, and cost-effective for using CAR T cell therapy in cancer immunotherapy. Besides CAR T cell application, this platform technology has potential for many other applications such as cancer cell isolation.
FILED Monday, September 26, 2022
APPL NO 17/935259
ART UNIT 1799 — Organic Chemistry
CURRENT CPC
Preparations for Medical, Dental, or Toilet Purposes
A61K 39/464 (20230501)
A61K 39/4611 (20230501)
A61K 39/4631 (20230501)
A61K 2239/38 (20230501)

Apparatus for Enzymology or Microbiology;
C12M 23/02 (20130101) Original (OR) Class
C12M 23/20 (20130101)
C12M 25/00 (20130101)

Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media
C12N 5/0062 (20130101)
C12N 5/0636 (20130101)

Investigating or Analysing Materials by Determining Their Chemical or Physical Properties
G01N 33/54313 (20130101)
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 12137012 Andrews
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) Raytheon Company (Waltham, Massachusetts)
ASSIGNEE(S) Raytheon Company (Tewksbury, Massachusetts)
INVENTOR(S) Macdonald J. Andrews (Douglas, Massachusetts)
ABSTRACT A method includes obtaining an in-phase (I) input signal and a quadrature (Q) input signal at a quadrature modulator. The method also includes performing constant envelope bi-phase shift keying (CE-BPSK) modulation using the quadrature modulator to generate a modulated output signal. The modulated output signal includes a CE-BPSK modulated waveform containing phase reversals, and the CE-BPSK modulated waveform has a substantially-constant amplitude during the phase reversals.
FILED Wednesday, July 13, 2022
APPL NO 17/812403
ART UNIT 2633 — Digital Communications
CURRENT CPC
Transmission of Digital Information, e.g Telegraphic Communication
H04L 27/20 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 12136923 Hall et al.
FUNDED BY
APPLICANT(S) Jeffrey S. Hall (Annapolis, Maryland);  Jonathan D. Egan (Hanover, Maryland);  Joseph A. Payne (Cooksville, Maryland)
ASSIGNEE(S) NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia)
INVENTOR(S) Jeffrey S. Hall (Annapolis, Maryland);  Jonathan D. Egan (Hanover, Maryland);  Joseph A. Payne (Cooksville, Maryland)
ABSTRACT One example includes a superconducting circuit chip. The chip includes superconducting circuitry that operates based on a clock signal. The chip also includes a ring oscillator configured to receive a synchronization signal from a ring oscillator associated with another superconducting circuit chip. The ring oscillator is also configured to provide a trigger signal to the superconducting circuitry at a given phase of the clock signal relative to a phase of the clock signal of a trigger signal associated with the other one of the superconducting circuit chips based on the synchronization signal.
FILED Thursday, March 02, 2023
APPL NO 18/177299
ART UNIT 2842 — Electrical Circuits and Systems
CURRENT CPC
Computer Systems Based on Specific Computational Models
G06N 10/40 (20220101)

Pulse Technique
H03K 3/0315 (20130101)
H03K 17/92 (20130101)

Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses
H03L 7/06 (20130101) Original (OR) Class
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, November 05, 2024.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20241105.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

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