FedInvent™ Patents
Patent Details for Tuesday, November 12, 2024
This page was updated on Tuesday, November 12, 2024 at 06:32 PM GMT
Department of Health and Human Services (HHS)
12137975 — Systems, methods, and program products for performing on-off perimetry visual field tests
US 12137975 | Alonso et al. |
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FUNDED BY |
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APPLICANT(S) | Research Foundation for the State University of New York (Albany, New York) |
ASSIGNEE(S) | The Research Foundation for the State University of New York (Albany, New York) |
INVENTOR(S) | José-Manuel Alonso (New York, New York); Mitchell Dul (Cold Spring, New York); Hamed Rahimi Nasrabadi (Brooklyn, New York) |
ABSTRACT | Systems for performing ON-OFF perimetry visual field tests. The systems may include a display apparatus including at least one display, and at least one computing device in electronic communication with the display apparatus. The computing device(s) may be configured to perform the ON-OFF perimetry test on a patient by performing processes including directing the patient to visual focus on an eye fixation region depicted in a visual field. The visual field may be divided into a right side and a left side. The processes performed by the computing device(s) may also include generating a plurality of stimuli in the visual field to be detected by the patient, directing the patient to indicate when the patient detects each stimulus depicted within the visual field, and analyzing the patient's indications to diagnosis a retinal disease, a visual cortex disease, and/or a deficit condition of an eye of the patient. |
FILED | Tuesday, March 30, 2021 |
APPL NO | 17/217553 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/024 (20130101) Original (OR) Class A61B 3/0025 (20130101) A61B 3/0041 (20130101) A61B 3/113 (20130101) A61B 2562/0219 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138034 | Langer et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Robert S. Langer (Newton, Massachusetts); Carlo Giovanni Traverso (Newton, Massachusetts); Malvika Verma (Cambridge, Massachusetts); Feyisope Eweje (Jacksonville, North Carolina); Christoph Winfried Johannes Steiger (Cambridge, Massachusetts); Junwei Li (Cambridge, Massachusetts); Nhi Phan (Somerville, Massachusetts); Hen-Wei Huang (Cambridge, Massachusetts); Jacqueline Chu (Boston, Massachusetts); John Ashraf Fou Salama (Cambridge, Massachusetts) |
ABSTRACT | Drug delivery articles, resident articles, and retrieval systems e.g., for gram-level dosing, are generally provided. In some embodiments, the residence articles are configured for transesophageal administration, transesophageal retrieval, and/or gastric retention to/in a subject. In certain embodiments, the residence article includes dimensions configured for transesophageal administration with a gastric resident system. In some cases, the residence article may be configured to control drug release e.g., with zero-order drug kinetics with no potential for burst release for weeks to months. In some embodiments, the residence articles described herein comprise biocompatible materials and/or are safe for gastric retention. In certain embodiments, the residence article includes dimensions configured for transesophageal retrieval. In some cases, the residence articles described herein may comprise relatively large doses of drug (e.g., greater than or equal to 1 gram). |
FILED | Friday, December 15, 2023 |
APPL NO | 18/541818 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/073 (20130101) Original (OR) Class A61B 5/4845 (20130101) A61B 2562/02 (20130101) A61B 2562/162 (20130101) A61B 2562/164 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138205 | Reinkensmeyer et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
INVENTOR(S) | David Reinkensmeyer (Irvine, California); Daniel Zondervan (Irvine, California); Marti Comellas Andres (Irvine, California) |
ABSTRACT | In one embodiment, a wheelchair device includes a frame adapted to be removably mounted to a wheelchair, a slide member supported by the frame that is configured to be pushed in a forward direction away from a user of the device with the user's arm, a transmission mechanism including a rotatable reel and a spring associated with the reel that resists rotation of the reel in a first direction and assists rotation of the reel in a second direction, and a cable having first and second ends, the first end of the cable being attached to the slide member and the second end being attached to the rotatable reel. With such a configuration, movement of the slide member in the forward direction causes the rotatable reel to rotate in the first direction and movement of the slide member in a backward direction opposite to the forward direction causes the rotatable reel to rotate in the second direction. |
FILED | Thursday, July 22, 2021 |
APPL NO | 17/383113 |
ART UNIT | 3611 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Transport, Personal Conveyances, or Accommodation Specially Adapted for Patients or Disabled Persons; Operating Tables or Chairs; Chairs for Dentistry; Funeral Devices A61G 5/045 (20130101) Original (OR) Class A61G 5/125 (20161101) A61G 2203/14 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138261 | Distelhorst |
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FUNDED BY |
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APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
INVENTOR(S) | Clark Distelhorst (Cleveland, Ohio) |
ABSTRACT | Compounds and pharmaceutical compositions thereof for inducing apoptosis in a cell expressing Bcl-2 and IP3R and their use in a method for treating neoplastic disorders in a subject. |
FILED | Tuesday, January 25, 2022 |
APPL NO | 17/583602 |
ART UNIT | 1678 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/44 (20130101) A61K 31/421 (20130101) A61K 31/495 (20130101) Original (OR) Class A61K 31/496 (20130101) A61K 31/5377 (20130101) A61K 38/17 (20130101) A61K 45/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138284 | Monroe et al. |
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FUNDED BY |
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APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
ASSIGNEE(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
INVENTOR(S) | Tanner Monroe (Houston, Texas); John Leach (Houston, Texas); James F. Martin (Pearland, Texas) |
ABSTRACT | The present disclosure encompasses methods for generating cells or tissue from existing cells with one or more mutated variants of Yap. In specific embodiments, the disclosure regards treatment of existing cardiomyocytes with one or more mutated variants of Yap that causes them to divide and generate new cardiomyocytes. In specific cases, the mutated variant of Yap has serine-to-alanine substitutions at 1, 2, 3, 4, 5, 6, or more serines of Yap. |
FILED | Monday, September 12, 2022 |
APPL NO | 17/931493 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) A01K 2217/072 (20130101) A01K 2227/105 (20130101) A01K 2267/0375 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 48/00 (20130101) Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0657 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138285 | Kenny et al. |
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FUNDED BY |
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APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | |
INVENTOR(S) | Douglas Kenny (Cambridge, Massachusetts); Hera Vlamakis (Cambridge, Massachusetts); Ramnik Xavier (Cambridge, Massachusetts); Emily Balskus (Cambridge, Massachusetts); Damian Plichta (Cambridge, Massachusetts) |
ABSTRACT | Microbes expressing cholesterol oxidoreductase (COR) proteins, methods of engineering the microbes expressing COR proteins, compositions and methods of using the microbes are provided. |
FILED | Monday, March 06, 2023 |
APPL NO | 18/178966 |
ART UNIT | 1759 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/575 (20130101) A61K 35/741 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 15/70 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/10 (20130101) C12Q 1/26 (20130101) Enzymes C12Y 101/03006 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/902 (20130101) G01N 2800/044 (20130101) G01N 2800/50 (20130101) G01N 2800/065 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138293 | Ghatnekar et al. |
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FUNDED BY |
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APPLICANT(S) | XEQUEL BIO, INC. (Mount Pleasant, South Carolina) |
ASSIGNEE(S) | XEQUEL BIO, INC. (Mount Pleasant, South Carolina) |
INVENTOR(S) | Gautam Ghatnekar (Mt. Pleasant, South Carolina); Christina Grek (Mt. Pleasant, South Carolina) |
ABSTRACT | This disclosure provides formulations suitable for topical ophthalmic delivery of peptide therapeutics. The disclosure also provides compositions and methods for treating ocular injury. The compositions and formulations may include therapeutically active alpha connexin peptides. |
FILED | Friday, October 22, 2021 |
APPL NO | 17/508388 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 47/02 (20130101) A61K 47/38 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138299 | Alenghat |
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FUNDED BY |
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APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
INVENTOR(S) | Theresa Alenghat (Cincinnati, Ohio) |
ABSTRACT | Disclosed herein are methods for enhancing an immune response in an individual in need thereof. The methods, in certain aspects, may comprise administering bacterial aldehyde dehydrogenase, a bacteria that produces aldehyde dehydrogenase, or combinations thereof to an individual. Further disclosed are compositions, such as nutritional compositions, which may comprise bacterial aldehyde dehydrogenase, a bacteria that produces aldehyde dehydrogenase, or combinations thereof. |
FILED | Wednesday, April 03, 2024 |
APPL NO | 18/625448 |
ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/44 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) A61P 37/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0008 (20130101) Enzymes C12Y 102/01003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138304 | Henderson et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Rory Henderson (Durham, North Carolina); S. Munir Alam (Durham, North Carolina); Barton F. Haynes (Durham, North Carolina); Kevin J. Wiehe (Durham, North Carolina) |
ABSTRACT | The technology is directed to HIV envelopes which comprise sequence modifications wherein these modifications prevent CD4-induced transitions of the HIV envelope. Specifically, the disclosure provides recombinant HIV-1 Env proteins comprising mutations, wherein the envelope is a protomer, and wherein three protomers form a trimer stabilized by the presence of the mutations. Provided also are compositions comprising envelopes of the technology, and methods of use. |
FILED | Thursday, September 05, 2019 |
APPL NO | 17/281918 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class Peptides C07K 14/162 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/63 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138305 | Weissman et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Drew Weissman (Wynnewood, Pennsylvania); Norbert Pardi (Philadelphia, Pennsylvania) |
ABSTRACT | The present invention relates to compositions and methods for inducing an adaptive immune response in a subject. In certain embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding an antigen, adjuvant, or a combination thereof. For example, in certain embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding an antigen, adjuvant, or a combination thereof. |
FILED | Monday, March 28, 2022 |
APPL NO | 17/705837 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/127 (20130101) A61K 31/712 (20130101) A61K 31/7115 (20130101) A61K 39/002 (20130101) A61K 39/02 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 39/145 (20130101) A61K 2039/51 (20130101) A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) A61P 31/18 (20180101) A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 219/08 (20130101) Heterocyclic Compounds C07D 295/13 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138321 | Ran et al. |
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FUNDED BY |
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APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
INVENTOR(S) | Chongzhao Ran (Winchester, Massachusetts); Anna Moore (Stoneham, Massachusetts); Jian Yang (Boston, Massachusetts) |
ABSTRACT | Provided herein are curcumin analogues that are able to interact with amyloid beta (Aβ) and to attenuate the copper-induced crosslinking of Aβ. Also provided herein are methods of using the compounds as imaging agents of amyloid beta and for the treatment of diseases associated with amyloid beta. Methods of preparing unlabeled and radiolabeled compounds useful for interacting with amyloid beta and pharmaceutical compositions are also provided. |
FILED | Wednesday, September 22, 2021 |
APPL NO | 17/448463 |
ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/04 (20130101) A61K 51/0453 (20130101) Original (OR) Class A61K 51/0455 (20130101) A61K 2123/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/28 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/002 (20130101) C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 49/248 (20130101) C07C 49/252 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/02 (20130101) C07F 5/022 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138366 | Zlotnick et al. |
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FUNDED BY |
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APPLICANT(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Hannah M. Zlotnick (Philadelphia, Pennsylvania); Andrew Todd Clark (North Wales, Pennsylvania); Robert L. Mauck (Philadelphia, Pennsylvania); Xuemei Cheng (Bryn Mawr, Pennsylvania) |
ABSTRACT | The present disclosure is concerned with magneto-patterned cell-laden hydrogel materials and methods of making and using those materials. The disclosed materials are useful for, among other things, repair of tissue defects, e.g., tissue at a tissue interface such as a bone-cartilage interface. |
FILED | Tuesday, April 13, 2021 |
APPL NO | 17/229829 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/042 (20130101) A61L 27/045 (20130101) A61L 27/46 (20130101) A61L 27/047 (20130101) A61L 27/52 (20130101) A61L 27/222 (20130101) A61L 27/225 (20130101) A61L 27/3847 (20130101) Original (OR) Class A61L 27/3852 (20130101) A61L 2300/41 (20130101) A61L 2300/43 (20130101) A61L 2300/258 (20130101) A61L 2300/402 (20130101) A61L 2300/406 (20130101) A61L 2300/408 (20130101) A61L 2300/414 (20130101) A61L 2300/426 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138369 | Nuxoll et al. |
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FUNDED BY |
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APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
ASSIGNEE(S) | University of lowa Research Foundation (lowa City, Iowa) |
INVENTOR(S) | Eric Nuxoll (Iowa City, Iowa); Joel Coffel (Iowa City, Iowa); Erica Ricker (Iowa City, Iowa) |
ABSTRACT | A system for disrupting a biofilm on a medical device that comprises an implantable medical device; a magnetically-sensitive coating on the surface of the implantable device comprising a polymer and magnetic particles embedded within the polymer; and a coil element capable of generating an alternating magnetic field, wherein the coil element is constructed and arranged to be capable of applying an alternating magnetic field to induce heating of the surface of the implantable device. |
FILED | Tuesday, June 27, 2017 |
APPL NO | 16/312680 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/04 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0077 (20130101) A61F 7/00 (20130101) A61F 7/12 (20130101) A61F 7/123 (20130101) A61F 2007/126 (20130101) A61F 2210/009 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/00 (20130101) A61L 27/34 (20130101) A61L 27/50 (20130101) A61L 29/14 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/14 (20130101) Original (OR) Class A61L 2400/18 (20130101) A61L 2420/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2/002 (20130101) A61N 2/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138398 | Tsai et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Li-Huei Tsai (Cambridge, Massachusetts); Emery Brown (Brookline, Massachusetts); Hannah Iaccarino (Somerville, Massachusetts); Anthony James Martorell (Cambridge, Massachusetts); Chinnakkaruppan Adaikkan (Somerville, Massachusetts) |
ABSTRACT | A method includes administering a non-invasive stimulus to a subject having a frequency of about 35 Hz to about 45 Hz to induce synchronized gamma oscillations in at least one brain region of the subject. |
FILED | Monday, June 15, 2020 |
APPL NO | 16/901628 |
ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/00 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/00 (20130101) Original (OR) Class A61M 2021/0022 (20130101) A61M 2021/0027 (20130101) A61M 2021/0044 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/062 (20130101) A61N 5/0618 (20130101) A61N 5/0622 (20130101) A61N 2005/063 (20130101) A61N 2005/0651 (20130101) A61N 2005/0662 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138416 | McAllister et al. |
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FUNDED BY |
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APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
INVENTOR(S) | Devin V. McAllister (Marietta, Georgia); Mark R. Prausnitz (Atlanta, Georgia); Sebastien Henry (Smyrna, Georgia) |
ABSTRACT | Drug delivery devices and methods are provided for delivering one or more drugs into a biological tissue. The devices include microneedles that may be separable from the drug delivery devices, control drug release rate and/or direction, or a combination thereof. When the microneedles are separable, a force applied to the drug delivery devices may be effective to penetrate a biological tissue with the microneedles and then to separate the microneedles from the drug delivery devices. The drug delivery devices may be capable of achieving discrete periods of drug release. Methods for delivery drug with microneedles also are provided. |
FILED | Wednesday, February 24, 2021 |
APPL NO | 17/184140 |
ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0007 (20130101) A61M 2037/0023 (20130101) A61M 2037/0046 (20130101) A61M 2037/0061 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138456 | Lim et al. |
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FUNDED BY |
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APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
INVENTOR(S) | Hubert H. Lim (Minneapolis, Minnesota); Craig D. Markovitz (Minneapolis, Minnesota); Sarah J. Offutt (Minneapolis, Minnesota) |
ABSTRACT | The invention provides methods for treating a neurological disorder or deficit, such as tinnitus and phantom limb pain. |
FILED | Thursday, February 11, 2021 |
APPL NO | 17/174045 |
ART UNIT | 3796 — Body Treatment, Kinestherapy, and Exercising |
CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/00 (20130101) A61F 11/00 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 23/0236 (20130101) A61H 2201/10 (20130101) A61H 2201/0207 (20130101) A61H 2201/1604 (20130101) A61H 2205/027 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 21/00 (20130101) A61M 2021/0027 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/361 (20130101) Original (OR) Class A61N 1/36025 (20130101) A61N 1/36036 (20170801) A61N 1/36038 (20170801) A61N 1/36067 (20130101) A61N 1/36071 (20130101) A61N 1/36082 (20130101) A61N 1/36096 (20130101) A61N 1/36167 (20130101) A61N 2/002 (20130101) A61N 2/02 (20130101) A61N 2/006 (20130101) A61N 5/0622 (20130101) A61N 7/00 (20130101) A61N 2007/0026 (20130101) A61N 2007/0043 (20130101) A61N 2007/0073 (20130101) A61N 2007/0078 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138490 | Christiano et al. |
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FUNDED BY |
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APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
ASSIGNEE(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
INVENTOR(S) | Angela M. Christiano (Mahwah, New Jersey); Raphael Clynes (West Nyack, New York) |
ABSTRACT | The invention provides for methods for treating a hair loss disorder in a subject by administering a Janus Kinase/Signal Transducers and Activators of Transcription inhibitor. |
FILED | Wednesday, April 06, 2022 |
APPL NO | 17/714964 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/41 (20130101) A61K 8/64 (20130101) A61K 8/4953 (20130101) A61K 31/52 (20130101) A61K 31/63 (20130101) A61K 31/137 (20130101) A61K 31/277 (20130101) A61K 31/407 (20130101) A61K 31/437 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/529 (20130101) A61K 31/553 (20130101) A61K 31/713 (20130101) A61K 31/5377 (20130101) A61K 31/7052 (20130101) A61K 2800/782 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 7/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139470 | Renslo et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Adam Robert Renslo (Oakland, California); Brian Richard Blank (Daly City, California); Ryan Keith Muir (Colma, California); Michael John Evans (South San Francisco, California); Poulami Talukder (Cambridge, Massachusetts) |
ABSTRACT | Disclosed herein, inter alia, are trioxolane compounds and methods of using the same for treatment and detection of diseases. |
FILED | Friday, February 25, 2022 |
APPL NO | 17/680825 |
ART UNIT | 1624 — Organic Chemistry |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) Heterocyclic Compounds C07D 323/02 (20130101) Original (OR) Class C07D 405/12 (20130101) C07D 407/12 (20130101) C07D 413/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139472 | Khalifah |
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FUNDED BY |
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APPLICANT(S) | PRAETEGO INC (Durham, North Carolina) |
ASSIGNEE(S) | Praetego Inc (Durham, North Carolina) |
INVENTOR(S) | Raja G. Khalifah (Raleigh, North Carolina) |
ABSTRACT | The present disclosure provides compounds of the formula pharmaceutical compositions, and methods for treating or inhibiting development of AGE- and/or ALE-associated complications in subjects in need thereof. |
FILED | Monday, February 01, 2021 |
APPL NO | 17/164817 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Heterocyclic Compounds C07D 213/38 (20130101) C07D 233/64 (20130101) C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139481 | Hubin et al. |
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FUNDED BY |
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APPLICANT(S) | Southwestern Oklahoma State University (Weatherford, Oklahoma); University of Mississippi (University, Mississippi) |
ASSIGNEE(S) | Southwestern Oklahoma State University (Weatherford, Oklahoma); University of Mississippi (University, Mississippi) |
INVENTOR(S) | Timothy J. Hubin (Weatherford, Oklahoma); M. O. Faruk Khan (Weatherford, Oklahoma); Stephen James Archibald (Hull, United Kingdom); Babu Lal Tekwani (Oxford, Mississippi) |
ABSTRACT | Compositions are disclosed herein that include macrocycle derivatives incorporating bridged macrocycles. Also disclosed are methods of producing and using the compositions. |
FILED | Tuesday, October 20, 2020 |
APPL NO | 17/075167 |
ART UNIT | 1627 — Organic Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/4985 (20130101) A61K 31/4995 (20130101) A61K 33/30 (20130101) A61K 33/32 (20130101) A61K 33/34 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) A61P 31/04 (20180101) A61P 31/10 (20180101) Heterocyclic Compounds C07D 273/00 (20130101) C07D 401/04 (20130101) C07D 471/00 (20130101) Original (OR) Class C07D 487/04 (20130101) C07D 519/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/582 (20130101) G01N 2800/26 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139509 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland (College Park, Maryland) |
ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
INVENTOR(S) | Lai-Xi Wang (Ellicott City, Maryland); Xiao Zhang (Xuzhou, China PRC) |
ABSTRACT | The present disclosure provides a one-pot chemoenzymatic method for site-specific modification and conjugation of antibodies at their Fc glycan site to produce structurally well-defined antibody conjugates carrying defined drugs and other entities. The method is enabled by the discovery that certain endoglycosidases have the ability to both deglycosylate an antibody and to recognize selectively modified small disaccharide oxazolines for transglycosylation on antibodies without hydrolysis of the resulting products. |
FILED | Thursday, February 02, 2023 |
APPL NO | 18/163496 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 1/12 (20130101) Original (OR) Class C07K 16/00 (20130101) C07K 2317/41 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Enzymes C12Y 302/01096 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139527 | Wilson et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Patrick Wilson (Chicago, Illinois); Yaoqing Chen (Chicago, Illinois); Haley L. Dugan (Chicago, Illinois) |
ABSTRACT | Provided herein are anti-neuraminidase agents useful for neutralization of influenza virus infection, and methods of use and manufacture thereof. In particular, compositions comprising anti-neuraminidase agents (e.g., antibodies) that are cross-reactive with multiple influenza strains are provided, as well as methods of treatment and prevention of influenza infection therewith. |
FILED | Thursday, June 15, 2023 |
APPL NO | 18/335872 |
ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/42 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 16/1018 (20130101) Original (OR) Class C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/565 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139532 | Rothstein et al. |
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FUNDED BY |
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APPLICANT(S) | ImmuNext, Inc. (Lebanon, New Hampshire); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
ASSIGNEE(S) | ImmuNext, Inc. (Lebanon, New Jersey); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
INVENTOR(S) | Jay Rothstein (Norwich, Vermont); Isabelle Lemercier (Enfield, New Hampshire); Linda Snyder (Pottstown, Pennsylvania); Gordon Powers (Malvern, Pennsylvania) |
ABSTRACT | The invention provides agonistic anti-human VISTA antibodies and antibody fragments. These agonist antibodies and antibody fragments may be used to potentiate or enhance or mimic VISTA's suppressive effects on T cell immunity and thereby suppress T cell immunity. These agonist antibodies and antibody fragments are especially useful in the treatment of autoimmunity, allergy, inflammatory conditions, GVHD, sepsis and transplant recipients. Screening assays for identifying these agonists are also provided. |
FILED | Monday, April 17, 2017 |
APPL NO | 15/489254 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 39/395 (20130101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 1/16 (20180101) A61P 13/12 (20180101) A61P 17/06 (20180101) A61P 19/02 (20180101) A61P 37/06 (20180101) Peptides C07K 16/2803 (20130101) Original (OR) Class C07K 16/2827 (20130101) C07K 16/2896 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/31 (20130101) C07K 2317/33 (20130101) C07K 2317/34 (20130101) C07K 2317/52 (20130101) C07K 2317/53 (20130101) C07K 2317/73 (20130101) C07K 2317/74 (20130101) C07K 2317/75 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/522 (20130101) C07K 2317/565 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139535 | Freeman et al. |
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FUNDED BY |
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APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
INVENTOR(S) | Gordon J. Freeman (Brookline, Massachusetts); Yanping Xiao (Brookline, Massachusetts) |
ABSTRACT | The present invention relates to methods for upregulating immune responses using combinations of anti-RGMb and anti-PD-1 agents. |
FILED | Monday, August 23, 2021 |
APPL NO | 17/409118 |
ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 39/39541 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/28 (20130101) C07K 16/2818 (20130101) Original (OR) Class C07K 2317/31 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2320/31 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139539 | Wu |
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FUNDED BY |
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APPLICANT(S) | Cancure, LLC (Shoreline, Washington) |
ASSIGNEE(S) | CanCure, LLC (Shoreline, Washington) |
INVENTOR(S) | Jennifer Wu (Wilmette, Illinois) |
ABSTRACT | The present invention provides MIC antibodies, antigen binding portions thereof and MIC binding agents thereof for use in the treatment of cancer. |
FILED | Tuesday, October 25, 2022 |
APPL NO | 18/049434 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2833 (20130101) Original (OR) Class C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139542 | Layne et al. |
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FUNDED BY |
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APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
INVENTOR(S) | Matthew D. Layne (Dedham, Massachusetts); Kathleen E. Tumelty (Brookline, Massachusetts); Robert Lafyatis (Arlington, Massachusetts) |
ABSTRACT | The present invention generally relates to the field of treatment of fibroproliferative diseases and disorders and cancer. Embodiments of the present invention generally relate to compostions, methods and kits comprising an inhibitor of a portion of the N-terminal pro-fibrotic domain (PFD) of Aortic Carboxypeptidase-Like Protein (ACLP), and in some embodiments, in combination with an inhibitor of the discoidin (DS) domain of ACLP, for use in methods for the treatment of fibroproliferative diseases and cancer, and inhibition of ACLP-mediated activation of a member of the TGFβ receptor superfamily. |
FILED | Wednesday, May 27, 2015 |
APPL NO | 15/313257 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/16 (20130101) Peptides C07K 16/2863 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139550 | Puré et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Ellen Puré (Bryn Mawr, Pennsylvania); Leslie Todd (Conshohocken, Pennsylvania) |
ABSTRACT | The present invention relates to antibodies, binding polypeptides, and scFvs specific for fibroblast activation protein (FAP) capable of cross reacting with canine, mouse, and human FAP. |
FILED | Wednesday, September 23, 2020 |
APPL NO | 17/029284 |
ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Peptides C07K 16/40 (20130101) Original (OR) Class C07K 2317/33 (20130101) C07K 2317/56 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) G01N 2333/96425 (20130101) G01N 2800/52 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139708 | Badran et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Borad Institute, Inc. (Cambridge, Massachusetts) |
INVENTOR(S) | Ahmed Hussein Badran (Cambridge, Massachusetts); Erika Alden DeBenedictis (Cambridge, Massachusetts); Kevin Michael Esvelt (Newton, Massachusetts) |
ABSTRACT | The invention, in part, includes compositions comprising quadruplet decoding tRNAs and their encoding sequences. The invention also includes assay methods to assess quadruplet decoding as well as methods of preparing quadruplet decoding suppression tRNAs. |
FILED | Friday, June 05, 2020 |
APPL NO | 16/894359 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/1058 (20130101) C12N 15/8509 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139721 | Irvine et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Darrell J. Irvine (Arlington, Massachusetts); Ron Weiss (Newton, Massachusetts); Yingzhong Li (Quincy, Massachusetts); Jan Lonzaric (Arlington, Massachusetts); Parisa Yousefpour (Cambridge, Massachusetts) |
ABSTRACT | Genetic circuits have been developed to regulate behaviors of replicon RNA in responses to small molecules, which has broader applications, such as for quantitative expression of cargo genes, temporary expression of immunomodulatory cytokines or antigens for better cancer immunotherapy or vaccination, and for increased safety in use of self-replicating vectors or in combination with other viral-delivery vectors. Described herein are genetic circuits suitable for systems that either require a tight off state or a slow off state, which can serve for instance where either a kill switch or prolonged protein expression (e.g., of vaccine antigens) are needed. |
FILED | Thursday, April 15, 2021 |
APPL NO | 17/231588 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/505 (20130101) A61K 31/713 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2720/12322 (20130101) C12N 2720/12343 (20130101) C12N 2820/60 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139731 | Wiedenheft et al. |
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FUNDED BY |
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APPLICANT(S) | Montana State University (Bozeman, Montana) |
ASSIGNEE(S) | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS) U.S. GOVERNMENT (Bethesda, Maryland) |
INVENTOR(S) | Blake A. Wiedenheft (Bozeman, Montana); Joseph E. Nichols (Bozeman, Montana); Anna A. Nemudraia (Bozeman, Montana); Artem A. Nemudryi (Bozeman, Montana) |
ABSTRACT | CRISPR RNA-guided nucleases are routinely used for sequence-specific manipulation of DNA. While CRISPR-based DNA editing has become routine, analogous methods for editing RNA have yet to be established. Here we repurpose the type III-A CRISPR RNA-guided nuclease for sequence-specific cleavage of the SARS-CoV-2 genome. The type III cleavage reaction is performed in vitro using purified viral RNA, resulting in sequence-specific excision of 6, 12, 18 or 24 nucleotides. Ligation of the cleavage products is facilitated by a DNA splint that bridges the excision and RNA ligase is used to link the RNA products before transfection into mammalian cells. The SARS-CoV-2 RNA is infectious and standard plaque assays are used to recover viral clones. Collectively, this work demonstrates how type III CRISPR systems can be repurposed for sequence-specific editing of RNA viruses including SARS-CoV-2 and more generally for gene therapy. |
FILED | Friday, July 08, 2022 |
APPL NO | 17/811391 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/66 (20130101) C12N 2310/20 (20170501) C12N 2770/20021 (20130101) C12N 2770/20052 (20130101) C12N 2800/80 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139749 | Pourmand et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Nader Pourmand (San Mateo, California); Miloslav Karhanek (Santa Cruz, California); Ronald W. Davis (Stanford, California) |
ABSTRACT | Methods and apparatus for direct detection of chemical reactions are provided. Electric charge perturbations of the local environment during enzyme-catalyzed reactions are sensed by an electrode system with an immobilized target molecule. The charge perturbation caused by the polymerase reaction can uniquely identify a DNA sequence. The polymerization process generates local perturbations of charge in the solution near the electrode surface and induces a charge in a polarazible gold electrode. This event is detected as a transient current by a voltage clamp amplifier. Detection of single nucleotides in a sequence can be determined by dispensing individual dNTPs to the electrode solution and detecting the charge perturbations. Alternatively, multiple bases can be determined at the same time using a mix of all dNTPs with subsequent analysis of the resulting signal. This technique may be adapted to other reaction determinations, such as enzymatic reactions, other electrode configurations, and other amplifying circuits. |
FILED | Monday, November 02, 2020 |
APPL NO | 17/087336 |
ART UNIT | 1796 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) B82Y 30/00 (20130101) B82Y 40/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/3275 (20130101) G01N 27/3276 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139762 | Hakonarson et al. |
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FUNDED BY |
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APPLICANT(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (Philadelphia, Pennsylvania) |
INVENTOR(S) | Hakon Hakonarson (Malvern, Pennsylvania); Berta Almoguera (Philadelphia, Pennsylvania); Lyam Vazquez (Philadelphia, Pennsylvania); Patrick Sleiman (Philadelphia, Pennsylvania) |
ABSTRACT | Compositions and methods for the detection and treatment of ADHD are provided. |
FILED | Thursday, February 16, 2023 |
APPL NO | 18/170241 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/136 (20130101) C12Q 2600/156 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139764 | Watson-Hurthig et al. |
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FUNDED BY |
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APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
INVENTOR(S) | Adam Watson-Hurthig (Tucson, Arizona); Ghassan Mouneimne (Tucson, Arizona); Casey Romanoski (Tucson, Arizona); Adam Grant (Tucson, Arizona); Megha Padi (Tucson, Arizona) |
ABSTRACT | Provided herein are compositions and methods for characterizing and treating cancer. In particular, provided herein are compositions and methods for identifying subjects with breast cancer with increased likelihood of bone metastasis and providing treatment to prevent such metastases. |
FILED | Thursday, November 14, 2019 |
APPL NO | 17/293578 |
ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139767 | Ma et al. |
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FUNDED BY |
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APPLICANT(S) | Bing Ma (Clarksville, Maryland); Rose Viscardi (Timonium, Maryland); Jacques Ravel (Laurel, Maryland) |
ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
INVENTOR(S) | Bing Ma (Clarksville, Maryland); Rose Viscardi (Timonium, Maryland); Jacques Ravel (Laurel, Maryland) |
ABSTRACT | A correlative finding between increased Clostridiales and/or Bifidobacteriales bacterial abundance in the gut and intestinal barrier maturation of preterm neonates at-risk for development of necrotizing enterocolitis (NEC) is disclosed. These findings form the basis for the methods of identifying preterm infants at risk for developing necrotizing enterocolitis (NEC), the methods of treating such infants, as well as the methods of characterizing intestinal permeability in preterm infants disclosed herein. |
FILED | Wednesday, May 22, 2019 |
APPL NO | 17/056562 |
ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139768 | Alland et al. |
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FUNDED BY |
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APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
INVENTOR(S) | David Alland (Bernardsville, New Jersey); Soumitesh Chakravorty (Somerset, New Jersey) |
ABSTRACT | The present invention relates to novel primers and sloppy molecular beacon and molecular beacon probes for amplifying segments from different genes in Mycobacterium tuberculosis for identifying the presence of M.tb DNA and/or resistance to anti-tuberculosis drugs. |
FILED | Tuesday, November 16, 2021 |
APPL NO | 17/527576 |
ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6865 (20130101) C12Q 2525/143 (20130101) C12Q 2525/185 (20130101) C12Q 2600/16 (20130101) C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139821 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Qihan Liu (Cambridge, Massachusetts); Kevin Kit Parker (Cambridge, Massachusetts); Huibin Chang (Cambridge, Massachusetts) |
ABSTRACT | Systems and methods for focused direction deposition of a micron or nanometer dimension polymeric fiber and materials of such fibers are described herein. Systems and methods employ one or more gas flows to entrain and deflect fibers produced by a rotary jet spinning system forming a focused fiber stream. Some embodiments enable control of alignment and distribution of the fibers with a relatively high fiber throughput. |
FILED | Tuesday, January 14, 2020 |
APPL NO | 17/421047 |
ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/14 (20130101) Original (OR) Class D01D 5/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140534 | Thomas et al. |
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FUNDED BY |
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APPLICANT(S) | Sequitur Health Corp. (Scottsdale, Arizona) |
ASSIGNEE(S) | Sequitur Health Corp. (Scottsdale, Arizona) |
INVENTOR(S) | Marylaura L. Thomas (Scottsdale, Arizona); Leslie F. Thomas (Scottsdale, Arizona); Erica S. Forzani (Phoenix, Arizona); Phuoc H. H. Duong (Phoenix, Arizona) |
ABSTRACT | A device, e.g., sensing cartridge, includes a first member and a second member coupled to the first member. The first member is configured to separate a component from a feed solution, where the component has a hydrodynamic diameter greater than 0.01 micrometers (μm). The second member is configured to wick a permeate from the first member. |
FILED | Thursday, January 05, 2023 |
APPL NO | 18/093469 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) G01N 1/2205 (20130101) G01N 21/31 (20130101) Original (OR) Class G01N 33/4925 (20130101) G01N 2201/062 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140540 | Min et al. |
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FUNDED BY |
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APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
INVENTOR(S) | Wei Min (Fort Lee, New Jersey); Lixue Shi (Zhejiang, China PRC); Hanqing Xiong (Hubei, China PRC); Lu Wei (Anhui, China PRC) |
ABSTRACT | Exemplary computer-accessible medium, systems, and methods are described herein which can provide an excited fluorescence radiation. In accordance with certain exemplary embodiments of the present disclosure, an excited fluorescence radiation can be provided using a beam of a probe so as to excite a molecule to an excited state for a fluorescence emission to effectuate the excited fluorescence radiation. The molecule can be detected based on the fluorescence emission. For example, the beam of the probe can be either the near-infrared spectrum or the visible light spectrum. |
FILED | Monday, September 13, 2021 |
APPL NO | 17/473259 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 21/636 (20130101) Original (OR) Class G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 2021/655 (20130101) G01N 2021/6439 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140587 | Branton et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Daniel Branton (Lexington, Massachusetts); Stephen Jordan Fleming (Cincinnati, Ohio); Jene A. Golovchenko (Lexington, Massachusetts) |
ABSTRACT | A nanopore system provided herein includes first and second fluidic reservoirs in fluidic communication with a nanopore forming a fluidic path between the reservoirs. An enzyme clamp, provided in the first fluidic reservoir, abuts the nanopore and is reversibly bound to a sequential plurality of polymer subunits of a target polymer molecule in ionic solution. The clamp has an outer clamp diameter that is greater than the nanopore diameter. An electrical circuit includes an electrode in each of the reservoirs for applying a voltage bias across the nanopore. A pulse generator is connected in the electrical circuit to apply control pulses across the nanopore to step the clamp along sequential polymer subunits of the target polymer molecule. The system includes no fuel or source of fuel for the clamp. A controller is connected in the electrical circuit for controlling the collection of electrical indications of polymer subunits. |
FILED | Thursday, May 13, 2021 |
APPL NO | 17/319254 |
ART UNIT | 1759 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Separation B01D 71/74 (20130101) B01D 71/0211 (20220801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 2565/631 (20130101) Enzymes C12Y 306/01039 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/40 (20130101) G01N 33/48721 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140592 | James et al. |
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FUNDED BY |
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APPLICANT(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
ASSIGNEE(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma) |
INVENTOR(S) | Judith Ann James (Edmond, Oklahoma); Melissa Elizabeth Munroe (Edmond, Oklahoma) |
ABSTRACT | The present invention includes methods, systems, and kits, for identifying and modifying the treatment of a systemic lupus erythematosus (SLE) patient prior to the presence of autoantibodies, comprising: (a) obtaining a dataset representing protein expression level values for cytokines and molecules; (b) assessing the dataset for protein expression levels of at least one innate serum mediator; (c) assessing the dataset for protein expression levels of at least one adaptive serum mediator; and (d) determining the likelihood that the patient will develop SLE prior to the onset of autoantibodies when compared to a control. |
FILED | Friday, June 15, 2018 |
APPL NO | 16/009959 |
ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) Original (OR) Class G01N 33/6863 (20130101) G01N 2333/495 (20130101) G01N 2333/522 (20130101) G01N 2333/523 (20130101) G01N 2333/525 (20130101) G01N 2333/545 (20130101) G01N 2333/555 (20130101) G01N 2333/575 (20130101) G01N 2333/5428 (20130101) G01N 2333/5434 (20130101) G01N 2333/5443 (20130101) G01N 2800/104 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) G16B 5/20 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140595 | Chaudhuri et al. |
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FUNDED BY |
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APPLICANT(S) | Washington University (St. Louis, Missouri); NATIONAL INSTITUTES OF HEALTH (Bethesda, Maryland) |
ASSIGNEE(S) | WASHINGTON UNIVERSITY (St. Louis, Missouri); NATIONAL INSTITUTES OF HEALTH (Bethesda, Maryland) |
INVENTOR(S) | Aadel Chaudhuri (St. Louis, Missouri); Paul Jones (St. Louis, Missouri); Jeffrey Szymanski (St. Louis, Missouri); Angela Hirbe (St. Louis, Missouri); Russell Sundby (Baltimore, Maryland); John Shern (Bethesda, Maryland) |
ABSTRACT | Among the various aspects of the present disclosure is the provision of methods for detecting cancer in Neurofibromatosis Type 1 (NF1) patients. |
FILED | Thursday, January 27, 2022 |
APPL NO | 17/586676 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57488 (20130101) Original (OR) Class Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/20 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141660 | Jiang et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Liang Jiang (Chicago, Illinois); Filip D. Rozpedek (Chicago, Illinois); Kyungjoo Noh (Pasadena, California) |
ABSTRACT | Quantum repeaters and network architectures use two concatenated quantum error correction codes to increase the transmission range of quantum information. A block of data qubits collectively encode a second-layer logical qubit according to a second-layer code concatenated with a first-layer code. A first-layer quantum repeater first-layer corrects each data qubit based on a first-layer syndrome extracted therefrom. The first-layer quantum repeater transmits these first-layer-corrected qubits to a second-layer quantum repeater via a quantum communication channel. The first-layer quantum repeater also transmits the first-layer syndromes to the second-layer quantum repeater via a classical communication channel. After extracting a second-layer syndrome from the first-layer-corrected qubits, the second-layer quantum repeater uses the first-layer syndromes and second-layer syndrome to second-layer correct the first-layer-corrected qubits. The first-layer syndromes improve quantum error correction by reducing the number of sec-and-layer stabilizer measurements needed to determine which data qubits have an error. |
FILED | Friday, June 04, 2021 |
APPL NO | 18/000074 |
ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/70 (20220101) Original (OR) Class Transmission H04B 10/70 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141963 | Metzger et al. |
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FUNDED BY |
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APPLICANT(S) | THE ROCKEFELLER UNIVERSITY (New York, New York) |
ASSIGNEE(S) | THE ROCKEFELLER UNIVERSITY (New York, New York) |
INVENTOR(S) | Jakob Metzger (New York, New York); Fred Etoc (New York, New York); Ali Brivanlou (New York, New York); Eric Siggia (New York, New York) |
ABSTRACT | Systems and methods for identifying molecules that are biologically active against a disease, where the method can comprise culturing a first mammalian cell population under organoid formation conditions in the presence of a test molecule to obtain a first organoid, wherein the first mammalian cell population, when cultured under the organoid formation conditions in the absence of the test molecule, results in an organoid with a disease phenotype; imaging the first organoid following exposure to the test molecule; analyzing one or more images of the first organoid using a neural network that has been trained to assign a probability score of disease or non-disease ranging between 0% and 100%; assigning the first organoid a probability score ranging between 0% and 100%; wherein the test molecule is biologically active against the disease if the probability score of the first organoid is greater than a cutoff probability score of non-disease or lower than a cutoff probability score of disease. |
FILED | Friday, October 04, 2019 |
APPL NO | 17/282039 |
ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 2503/02 (20130101) C12N 2510/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 33/5014 (20130101) G01N 33/5076 (20130101) Electric Digital Data Processing G06F 18/214 (20230101) G06F 18/217 (20230101) Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2200/04 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) G06T 2207/30072 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/764 (20220101) G06V 20/698 (20220101) G06V 2201/03 (20220101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/00 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141975 | Buckler et al. |
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FUNDED BY |
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APPLICANT(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
INVENTOR(S) | Andrew J. Buckler (Boston, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts); David S. Paik (Boston, Massachusetts) |
ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
FILED | Wednesday, January 17, 2024 |
APPL NO | 18/415137 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Electric Digital Data Processing G06F 18/24 (20230101) G06F 18/211 (20230101) G06F 18/2148 (20230101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 3/00 (20130101) G06T 5/73 (20240101) G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10048 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10101 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/30096 (20130101) G06T 2207/30104 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/764 (20220101) G06V 20/69 (20220101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142351 | Pinter et al. |
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FUNDED BY |
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APPLICANT(S) | INTOUCH TECHNOLOGIES, INC. (Goleta, California) |
ASSIGNEE(S) | TELADOC HEALTH, INC. (Purchase, New York) |
INVENTOR(S) | Marco Pinter (Santa Barbara, California); Timothy C. Wright (Santa Barbara, California); H. Neal Reynolds (Severna Park, Maryland); Fuji Lai (Goleta, California); Yulun Wang (Goleta, California) |
ABSTRACT | A telepresence device may autonomously check patients. The telepresence device may determine the frequency of checking based on whether the patient has a risk factor. The telepresence device may include an image sensor, a thermal camera, a depth sensor, one or more systems for interacting with patients, or the like. The telepresence device may be configured to evaluate the patient's condition using the one or more sensors. The telepresence device may measure physiological characteristics using Eulerian video magnification, may detect pallor, fluid level, or fluid color, may detect thermal asymmetry, may determine a psychological state from body position or movement, or the like. The telepresence device may determine whether the patient is experiencing a potentially harmful condition, such as sepsis or stroke, and may trigger an alarm if so. To overcome alarm fatigue, the telepresence device may annoy a care provider until the care provider responds to an alarm. |
FILED | Monday, May 21, 2018 |
APPL NO | 15/985448 |
ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0008 (20130101) A61B 5/0013 (20130101) A61B 5/015 (20130101) A61B 5/0022 (20130101) A61B 5/024 (20130101) A61B 5/0075 (20130101) A61B 5/0077 (20130101) A61B 5/165 (20130101) A61B 5/741 (20130101) A61B 5/742 (20130101) A61B 5/746 (20130101) A61B 5/1128 (20130101) A61B 5/02055 (20130101) A61B 5/4064 (20130101) A61B 5/4809 (20130101) A61B 5/7264 (20130101) A61B 5/7275 (20130101) A61B 34/10 (20160201) A61B 34/30 (20160201) Manipulators; Chambers Provided With Manipulation Devices B25J 9/1689 (20130101) B25J 11/009 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0038 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) Original (OR) Class G16H 40/67 (20180101) G16H 50/20 (20180101) Pictorial Communication, e.g Television H04N 7/148 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12143557 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Lihong Wang (Arcadia, California); Taewoo Kim (Alhambra, California); Jinyang Liang (Varennes, Canada); Liren Zhu (Sunnyvale, California) |
ABSTRACT | Compressed ultrafast photography (CUP) techniques that produce spatially encoded images from a first series of images where each spatially encoded image has first and second views of an image of the first series of images superimposed with a pseudo-random binary spatial pattern, that transform the first view and/or the second view such that the first view is rotated 180° relative to second view, that deflect each spatially encoded image by a temporal deflection distance that varies as a function of time-of-arrival, and that integrate the spatially encoded images into a CUP image. |
FILED | Tuesday, September 12, 2023 |
APPL NO | 18/465325 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 9/00 (20130101) G01J 2011/005 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4814 (20130101) G01S 7/4865 (20130101) G01S 17/894 (20200101) Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 21/10 (20130101) Pictorial Communication, e.g Television H04N 13/25 (20180501) H04N 13/161 (20180501) Original (OR) Class H04N 13/254 (20180501) H04N 13/282 (20180501) H04N 23/72 (20230101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12144260 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Xudong Wang (Middleton, Wisconsin); Fan Yang (Suzhou, China PRC); Jun Li (Madison, Wisconsin) |
ABSTRACT | A flexible piezoelectric thin film, and method of manufacture, has a polyvinyl alcohol (PVA)-glycine-PVA sandwich heterostructure. The thin film is manufactured by evaporating the solvent from a glycine-PVA mixture solution. The film automatically assembles into the PVA-glycine-PVA sandwich heterostructure as it is salted out. Strong hydrogen bonding between the oxygen atoms in glycine and hydroxyl groups on PVA chains are responsible for the nucleation and growth of the piezoelectric γ-glycine and alignment of the domain orientation. |
FILED | Thursday, January 21, 2021 |
APPL NO | 17/154711 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/18 (20130101) C08J 7/06 (20130101) C08J 2331/04 (20130101) C08J 2371/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) Electric solid-state devices not otherwise provided for H10N 30/02 (20230201) H10N 30/704 (20240501) Original (OR) Class H10N 30/872 (20230201) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
US 12137682 | Wei |
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FUNDED BY |
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APPLICANT(S) | X-THERMA, INC. (Richmond, California) |
ASSIGNEE(S) | X-Therma, Inc. (Hercules, California) |
INVENTOR(S) | Xiaoxi Wei (El Cerrito, California) |
ABSTRACT | The present invention provides peptoid polymers capable of reducing or inhibiting the formation of ice crystals at sub 0° C. temperatures. Also provided are peptoid-peptide hybrids comprising the peptoid polymers provided herein. The peptoid polymers and peptoid-peptide hybrids provided herein are useful for making cryoprotectant solutions. The peptoid polymers, peptoid-peptide hybrids, and cryoprotectant solutions provided herein are useful for making antifreeze solutions, frozen food products, and cosmetic care products. Also provided herein are methods for preserving a tissue, an organ, a cell, or a biological macromolecule using the compositions described herein. |
FILED | Wednesday, October 26, 2022 |
APPL NO | 17/974202 |
ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Original (OR) Class Preserving, e.g by Canning, Meat, Fish, Eggs, Fruit, Vegetables, Edible Seeds; Chemical Ripening of Fruit or Vegetables; the Preserved, Ripened, or Canned Products A23B 4/20 (20130101) Cocoa; Cocoa Products, e.g Chocolate; Substitutes for Cocoa or Cocoa Products; Confectionery; Chewing Gum; Ice-cream; Preparation Thereof A23G 9/32 (20130101) A23G 9/38 (20130101) Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 3/37 (20130101) A23L 3/3526 (20130101) A23L 13/42 (20160801) A23L 17/00 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 8/64 (20130101) A61K 8/88 (20130101) A61K 2800/54 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 90/00 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/001 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138348 | Eber et al. |
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FUNDED BY |
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APPLICANT(S) | CureVac SE (Tübingen, Germany) |
ASSIGNEE(S) | CureVac SE (Tübingen, Germany) |
INVENTOR(S) | Fabian Johannes Eber (Stuttgart, Germany); Benyamin Yazdan Panah (Tübingen, Germany); Stefanie Sewing (Tübingen, Germany); Thomas Ketterer (Gomaringen, Germany); Thorsten Mutzke (Reutlingen, Germany); Tilmann Roos (Kusterdingen, Germany); Michael Sonntag (Tübingen, Germany); Michael Wiggenhorn (Munich, Germany); Katharina Kolland (Augsburg, Germany) |
ABSTRACT | The present invention is directed to a storage-stable formulation of long-chain RNA. In particular, the invention concerns a dry powder composition comprising a long-chain RNA molecule. The present invention is furthermore directed to methods for preparing a dry powder composition comprising a long-chain RNA molecule by spray-freeze drying. The invention further concerns the use of such a dry powder composition comprising a long-chain RNA molecule in the preparation of pharmaceutical compositions and vaccines, to a method of treating or preventing a disorder or a disease, to first and second medical uses of such a dry powder composition comprising a long-chain RNA molecule and to kits, particularly to kits of parts, comprising such a dry powder composition comprising a long-chain RNA molecule. |
FILED | Monday, February 21, 2022 |
APPL NO | 17/676586 |
ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/1682 (20130101) Original (OR) Class A61K 31/7105 (20130101) A61K 48/005 (20130101) A61K 48/0091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138787 | Penn |
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FUNDED BY |
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APPLICANT(S) | James Douglass Penn (Cambridge, Mississippi) |
ASSIGNEE(S) | |
INVENTOR(S) | James Douglass Penn (Cambridge, Mississippi) |
ABSTRACT | A system and method for a planar positioning system for an output member, the system having a pair of x-coordinate linear carriages and a pair of y-coordinate linear carriages. The system has a guide mechanism for the pair of x-coordinate linear carriages and the pair of y-coordinate linear carriages. The system has a plurality of movement and constraining cables extending from the pair of x-coordinate linear carriages and the pair of y-coordinate linear carriages to the output member for driving the output, wherein the pair of x-coordinate linear carriages and the output member move in sync in the x-direction and the pair of y-coordinate linear carriages and the output member move in sync in the y-direction. A restraint mechanism restrains the output member in an additional degree of freedom besides the x- and y-directions. The restraint can be a cable uptake and release device. |
FILED | Thursday, April 28, 2022 |
APPL NO | 17/731705 |
ART UNIT | 3658 — Material and Article Handling |
CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/023 (20130101) Original (OR) Class B25J 9/026 (20130101) B25J 9/1045 (20130101) Gearing F16H 2019/069 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/21 (20130101) Technical Subjects Covered by Former US Classification Y10T 74/20341 (20150115) Y10T 74/20354 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138853 | Boydston et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Andrew Jackson Boydston (Middleton, Wisconsin); Evan Sherbrook (Cambridge, Massachusetts) |
ABSTRACT | In embodiments, a method for additive manufacturing of a metal-incorporated resin object comprises illuminating a curable composition comprising prepolymers, a metal compound, a photoredox catalyst, a polymerization initiator, and optionally, a redox agent, with light having a first wavelength, wherein the metal of the metal compound is characterized by an initial oxidation state, and the illumination induces polymerization reactions between prepolymers to form a first cured region and induces redox reactions to change the initial oxidation state of the metal in the first cured region. The method further comprises inducing polymerization reactions between prepolymers to form a second cured region different from the first cured region without inducing redox reactions in the second cured region. Also provided are the curable compositions, the additive manufacturing systems for carrying out the methods, and the metal-incorporated resin objects. |
FILED | Tuesday, March 16, 2021 |
APPL NO | 17/906405 |
ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) Original (OR) Class B29C 64/277 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/0002 (20130101) B29K 2505/00 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/10 (20200101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138904 | Boyd et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
INVENTOR(S) | Darryl A. Boyd (Alexandria, Virginia); Jason D. Myers (Alexandria, Virginia); Vinh Q. Nguyen (Fairfax, Virginia); Daniel J. Gibson (Cheverly, Maryland); Colin C. Baker (Alexandria, Virginia); Woohong Kim (Lorton, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
ABSTRACT | A bonded optical assembly comprising infrared-transparent materials. The assembly comprises two or more infrared transparent optical elements and a polymer comprising at least one chalcogenide element and crosslinking moieties between the infrared-transparent optical elements. The crosslinking moieties may be organic, inorganic, or both. |
FILED | Tuesday, November 07, 2023 |
APPL NO | 18/387576 |
ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/12 (20130101) Original (OR) Class B32B 7/023 (20190101) B32B 33/00 (20130101) B32B 37/1207 (20130101) B32B 2305/72 (20130101) B32B 2307/412 (20130101) B32B 2307/704 (20130101) B32B 2318/00 (20130101) B32B 2551/00 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 11/04 (20130101) C09J 163/00 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139027 | Pettey et al. |
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FUNDED BY |
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APPLICANT(S) | Response Technologies, LLC (Coventry, Rhode Island) |
ASSIGNEE(S) | RESPONSE TECHNOLOGIES, LLC (Coventry, Rhode Island) |
INVENTOR(S) | David Allen Pettey (Westport, Massachusetts); Edmund F. Bard (Cumberland, Rhode Island); Lao Vang (Providence, Rhode Island) |
ABSTRACT | A fuel cell containing fuel for an aircraft includes an innermost layer configured to contact the fuel, an outermost layer and a containment gel formed from isocyanate and polyol interposed between the innermost and outermost layers. The containment gel is configured to self-seal a ballistically formed hole therein, thereby reducing leakage of the fuel from the fuel cell. |
FILED | Tuesday, April 13, 2021 |
APPL NO | 17/228993 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/00 (20130101) B32B 5/02 (20130101) B32B 7/12 (20130101) B32B 27/12 (20130101) B32B 27/40 (20130101) B32B 2250/40 (20130101) B32B 2307/762 (20130101) B32B 2439/40 (20130101) B32B 2605/18 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 50/75 (20190201) Original (OR) Class Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 37/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139217 | Blankespoor et al. |
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FUNDED BY |
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APPLICANT(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
ASSIGNEE(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
INVENTOR(S) | Kevin Blankespoor (Arlington, Massachusetts); Alex Perkins (Arlington, Massachusetts); Marco da Silva (Arlington, Massachusetts) |
ABSTRACT | An example method may include i) determining a first distance between a pair of feet of a robot at a first time, where the pair of feet is in contact with a ground surface; ii) determining a second distance between the pair of feet of the robot at a second time, where the pair of feet remains in contact with the ground surface from the first time to the second time; iii) comparing a difference between the determined first and second distances to a threshold difference; iv) determining that the difference between determined first and second distances exceeds the threshold difference; and v) based on the determination that the difference between the determined first and second distances exceeds the threshold difference, causing the robot to react. |
FILED | Friday, January 21, 2022 |
APPL NO | 17/581361 |
ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1633 (20130101) B25J 9/1653 (20130101) B25J 9/1694 (20130101) B25J 13/08 (20130101) B25J 13/085 (20130101) Motor Vehicles; Trailers B62D 57/02 (20130101) Original (OR) Class B62D 57/032 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/021 (20130101) G05D 1/027 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/01 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139273 | Buckler et al. |
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FUNDED BY |
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APPLICANT(S) | Matthew Thomas Buckler (Fredericksburg, Virginia); Michael M. Canaday (King George, Virginia); Thomas Klebert Houck, Jr. (Woodford, Virginia); Gregory Noble Fish (King George, Virginia); William Michael McCoy, III (King George, Virginia); Nathan Arnold Lambert (King George, Virginia); Timothy Gerald Burcham (Fredericksburg, Virginia); Xavier Anthony Quinn (Alexandria, Virginia); Douglas Lawrence Ramers (Blanchard, Idaho); Sabrina Hong-Yee Lau (Spotsylvania, Virginia) |
ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
INVENTOR(S) | Matthew Thomas Buckler (Fredericksburg, Virginia); Michael M. Canaday (King George, Virginia); Thomas Klebert Houck, Jr. (Woodford, Virginia); Gregory Noble Fish (King George, Virginia); William Michael McCoy, III (King George, Virginia); Nathan Arnold Lambert (King George, Virginia); Timothy Gerald Burcham (Fredericksburg, Virginia); Xavier Anthony Quinn (Alexandria, Virginia); Douglas Lawrence Ramers (Blanchard, Idaho); Sabrina Hong-Yee Lau (Spotsylvania, Virginia) |
ABSTRACT | A recoil device is provided for a gun having a barrel with a breech. The device includes a breech nut, a brake assembly, a pneumatic spring and a counter-recoil buffer. The breech nut has first and second adjacent sides. The brake assembly includes a brake cylinder that mounts to the breech nut on the first side. The pneumatic spring mounts to the breech nut on the second side. The counter-recoil buffer attaches to the pneumatic spring. The brake cylinder and the pneumatic spring internally push fluids for recoil absorption and return in response to firing the gun. |
FILED | Tuesday, June 20, 2023 |
APPL NO | 18/211763 |
ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 7/02 (20130101) Original (OR) Class Functional Features or Details Common to Both Smallarms and Ordnance, e.g Cannons; Mountings for Smallarms or Ordnance F41A 25/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139417 | Dubois et al. |
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FUNDED BY |
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APPLICANT(S) | NANOIONIX, LLC (Farmington, Connecticut) |
ASSIGNEE(S) | NANOIONIX, LLC (Farmington, Connecticut) |
INVENTOR(S) | Lawrence H. Dubois (Danbury, Connecticut); Dana Alexa Totir (Sandy Hook, Connecticut) |
ABSTRACT | An antimicrobial material including a substrate and an antimicrobial mixed metal oxide, mixed metal sulfide, or mixed metal oxysulfide in and/or on the substrate is described, as well as antimicrobial coating materials and coatings formed therefrom. The antimicrobial material may be constituted in an antimicrobial surface of a surface-presenting substrate, to combat transmission and spread of microbial disease, e.g., disease mediated by microbial pathogens such as bacteria, viruses, and fungi. Antimicrobial mixed metal oxide, mixed metal sulfide, or mixed metal oxysulfide as described may be contacted with microorganisms to effect inactivation thereof. |
FILED | Tuesday, February 07, 2023 |
APPL NO | 18/165733 |
ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 59/02 (20130101) A01N 59/06 (20130101) A01N 59/20 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 45/1264 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/74 (20130101) C01P 2004/03 (20130101) C01P 2006/90 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139464 | Blackwell et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Helen Blackwell (Middleton, Wisconsin); Joseph Vasquez (Madison, Wisconsin); Yiftah Tal Gan (Reno, Nevada) |
ABSTRACT | Compounds provided are racemic, non-racemic or substantially enantiomerically pure dimers or salts or solvates thereof of formula: where: W and W′ are S or NR1, or —W—CO— or —W—CO— is —CH═CH—, where each R1 is hydrogen or an alkyl group having 1 to 3 carbon atoms; R and R′ are hydrogen or an straight-chain or branched alkyl group having 1-3 carbon atoms; R3 and R′3 are hydrogen or a C1-C3 alkyl; X1, X′1, X2 and X′2 are optionally-substituted straight-chain or branched alkyl groups having 3-8 carbon atoms, optionally-substituted cycloalkyl groups having 3-12 carbon atoms; optionally-substituted aryl, optionally-substituted heteroaryl, optionally-substituted heterocycyl, optionally-substituted cycloalkylalkyl, optionally-substituted arylalkyl, optionally-substituted heteroarylalkyl and optionally-substituted heterocycylalkyl groups and L1, L′1 and L2 are divalent chemical moieties. Dimers are employed to modulate quorum sensing and to thus inhibit virulence in Staphylococcus bacteria. Dimers are useful in treating infections of Staphylococcus bacteria. Methods for treating such bacterial infections are also provided. |
FILED | Monday, August 29, 2022 |
APPL NO | 17/823053 |
ART UNIT | 1759 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 273/00 (20130101) C07D 285/00 (20130101) C07D 291/02 (20130101) Original (OR) Class C07D 413/12 (20130101) C07D 417/12 (20130101) C07D 419/12 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139524 | Adusumilli et al. |
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APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
INVENTOR(S) | Prasad S. Adusumilli (New York, New York); Michel Sadelain (New York, New York) |
ABSTRACT | Disclosed herein are cells that are immune cells or precursor cells thereof, which cells recombinantly express a chimeric antigen receptor (CAR), and a dominant negative form of an inhibitor of a cell-mediated immune response of the immune cell, wherein the CAR binds to a cancer antigen. Also disclosed herein are T cells that recognize and are sensitized to a cancer antigen, which T cells recombinantly express a dominant negative form of an inhibitor of a T cell-mediated immune response. Additionally provided are methods of using such cells to treat cancer in a subject in need thereof. |
FILED | Tuesday, December 21, 2021 |
APPL NO | 17/557607 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/28 (20130101) A61K 38/00 (20130101) A61K 38/177 (20130101) A61K 38/193 (20130101) A61K 38/193 (20130101) A61K 38/1774 (20130101) A61K 38/2013 (20130101) A61K 38/2013 (20130101) A61K 38/4873 (20130101) A61K 39/0011 (20130101) A61K 39/00117 (20180801) A61K 39/00118 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) A61K 39/001109 (20180801) A61K 39/001112 (20180801) A61K 39/001113 (20180801) A61K 39/001114 (20180801) A61K 39/001119 (20180801) A61K 39/001122 (20180801) A61K 39/001124 (20180801) A61K 39/001126 (20180801) A61K 39/001128 (20180801) A61K 39/001129 (20180801) A61K 39/001153 (20180801) A61K 39/001157 (20180801) A61K 39/001166 (20180801) A61K 39/001168 (20180801) A61K 39/001171 (20180801) A61K 39/001174 (20180801) A61K 39/001182 (20180801) A61K 39/001186 (20180801) A61K 39/001188 (20180801) A61K 39/001192 (20180801) A61K 39/001193 (20180801) A61K 39/001195 (20180801) A61K 39/39558 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) Original (OR) Class C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/30 (20130101) C07K 16/3069 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0638 (20130101) C12N 9/6472 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 304/22062 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139809 | Rose et al. |
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FUNDED BY |
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APPLICANT(S) | Corrdesa, LLC (Tyrone, Georgia) |
ASSIGNEE(S) | Corrdesa, LLC (Tyrone, Georgia) |
INVENTOR(S) | Alan Rose (Newnan, Georgia); Keith Otto Legg (Peachtree City, Georgia) |
ABSTRACT | An electrochemical treatment system includes a treatment fluid supply manifold, a fluid return manifold, and an electrode section connected to the treatment fluid supply manifold. A plurality of treatment fluid supply ports feed fluid through or across the electrode and a plurality of fluid return ports proximate the treatment fluid supply ports are connected to the fluid return manifold. A porous pad is coupled to the electrode section for contacting a substrate to be treated and receives the treatment fluid via the plurality of treatment fluid supply ports. The plurality of fluid return ports remove spent and excess treatment fluid and gases from the substrate, the surrounding air, and the porous pad. |
FILED | Thursday, January 06, 2022 |
APPL NO | 17/569728 |
ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 5/02 (20130101) C25D 11/02 (20130101) C25D 21/04 (20130101) C25D 21/12 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140213 | Balsiger et al. |
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FUNDED BY |
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APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
INVENTOR(S) | Derick S. Balsiger (Prescott Valley, Arizona); Andrzej Ernest Kuczek (Bristol, Connecticut) |
ABSTRACT | A gear system, having: first and second ground gear; a drive shaft disposed along a rotation axis of the gear system and configured to rotate about the rotation axis; and an output gear supported by the first and second ground gear and configured to rotate by engagement between a wave generator portion of a drive shaft, a wave generator bearing, a flex spline, the output gear and the first and second ground gear, the output gear defining: an output gear body; and first and second output arms respectively extending radially outward from opposite sides of the output gear body to respectively define first and second radial inner ends and radial outer ends of the first and second output arms, so that the first and second radial outer ends are disposed on a radial axis that extends through a radial center of the gear system. |
FILED | Wednesday, August 11, 2021 |
APPL NO | 17/399289 |
ART UNIT | 3658 — Material and Article Handling |
CURRENT CPC | Aeroplanes; Helicopters B64C 13/34 (20130101) Gearing F16H 49/001 (20130101) Original (OR) Class F16H 2049/003 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140414 | Pankonien et al. |
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FUNDED BY |
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APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
INVENTOR(S) | Alexander Pankonien (Fairborn, Ohio); Joshua Deaton (Beavercreek, Ohio); Ryan Durscher (Loveland, Ohio) |
ABSTRACT | A method and system for measuring strain in a 3D printed part is disclosed herein. The printed part can be formed with internal features that can be analyzed with a digital image correlation system to determine strain levels in internal regions of the part. The features are visually identifiable due to a different color, shape, design or other visually distinguishable characteristics relative to that of the base structural material. The features can be the formed from the same material or a different material from that of the base structure material. |
FILED | Thursday, December 09, 2021 |
APPL NO | 17/546173 |
ART UNIT | 2483 — Recording and Compression |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/386 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 50/00 (20141201) B33Y 80/00 (20141201) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/16 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/001 (20130101) G06T 7/55 (20170101) G06T 7/74 (20170101) G06T 7/90 (20170101) G06T 2207/30144 (20130101) G06T 2207/30164 (20130101) Pictorial Communication, e.g Television H04N 23/56 (20230101) H04N 23/66 (20230101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140477 | Jarrahi et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Mona Jarrahi (Los Angeles, California); Ning Wang (Mountain View, California) |
ABSTRACT | A system for detecting high-frequency radiation that offers near-quantum-limited sensitivity, broad spectral bandwidth, and high spectral resolution while operating at room temperature. The system can include an antenna assembly configured to receive at least a high-frequency radiation and a substrate comprising a semiconductor material with a contact-semiconductor interface connected to the antenna assembly. The system also includes an optical pump configured to produce an optical beam that has a high-frequency beat frequency, the optical beam contacting the contact-semiconductor interface to create an intermediate frequency signal by combining the optical beam with the high-frequency radiation. The system further includes a detector configured to detect the intermediate frequency and generate at least one report indicating the received, high-frequency radiation. |
FILED | Monday, April 01, 2019 |
APPL NO | 17/044486 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/4338 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 9/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140548 | Garg et al. |
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FUNDED BY |
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APPLICANT(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
ASSIGNEE(S) | Virginia Tech Intellectual Properties, Inc. (Blacksburg, Virginia) |
INVENTOR(S) | Aditya Garg (Blacksburg, Virginia); Wei Zhou (Blacksburg, Virginia) |
ABSTRACT | Methods are provided for making a membrane or textile having a mechanically robust surface-enhanced Raman spectroscopy (SERS) substrate by in a first step adhesively bonding a micropatch array to a substrate, the micropatch array having a plurality of micron-scale pillars, each of the micron-scale pillars in the plurality of micron-scale pillars containing a plurality of plasmonic nanoparticles dispersed within a polymer matrix; and in a subsequent step etching a portion of the polymer matrix to expose at least a portion of the plasmonic nanoparticles at or near a surface of the micron-scale pillars. Membranes and textiles containing the mechanically robust surface-enhanced Raman spectroscopy (SERS) substrates are also provided. |
FILED | Tuesday, February 22, 2022 |
APPL NO | 17/677797 |
ART UNIT | 2877 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/44 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Original (OR) Class G01N 2021/656 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140726 | McGirr et al. |
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FUNDED BY |
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APPLICANT(S) | Naval Information Warfare Center Pacific (San Diego, California) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Scott C McGirr (San Diego, California); Ronald J Wroblewski (San Diego, California) |
ABSTRACT | The present invention relates to a remote tomography system. A filament system generates at least one plurality of plasma filaments. An electromagnetic radiation (EMR) system directs EMR towards the at least one plurality of plasma filaments such that the EMR reflects off of the at least one plurality of plasma filaments towards at least one target region. The EMR system is configured to receive EMR reflected from the at least one plurality of plasma filaments such that EMR reflecting from the at least one target region can be directed towards the EMR system. |
FILED | Tuesday, January 10, 2023 |
APPL NO | 18/152264 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Geophysics; Gravitational Measurements; Detecting Masses or Objects; Tags G01V 5/224 (20240101) G01V 5/226 (20240101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140774 | Wu et al. |
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FUNDED BY |
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APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | Chensheng Wu (Greenbelt, Maryland); Jonathan Ko (Davidsonville, Maryland); John R. Rzasa (College Park, Maryland); Christopher C. Davis (Annapolis, Maryland); Daniel Paulson (Hyattsville, Maryland) |
ABSTRACT | An afocal sensor assembly detects a light beam with an aberrated wavefront. The afocal sensor assembly is configured to provide sorted four-dimensional (4D) light field information regarding the light beam, for example, via one or more plenoptic images. Based on the 4D light field information, a lossy reconstruction of an aberrated wavefront for one or more actuators of an adaptive optics (AO) device is performed. The AO device can be controlled based on the lossy reconstruction to correct the wavefront of the light beam. In some embodiments, the aberrated wavefront is due to passage of the light beam through atmospheric turbulence, and the lossy reconstruction and correction using the AO device is performed in less than 1.0 ms. The lossy reconstruction of the aberrated wavefront can have a phase accuracy in a range of λ/2 to λ/30. |
FILED | Thursday, December 02, 2021 |
APPL NO | 17/540644 |
ART UNIT | 2878 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 3/0037 (20130101) G02B 27/0025 (20130101) G02B 27/0068 (20130101) G02B 27/0916 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 7/557 (20170101) G06T 2207/10052 (20130101) Pictorial Communication, e.g Television H04N 23/957 (20230101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141229 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | NVIDIA CORPORATION (Santa Clara, California) |
ASSIGNEE(S) | NVIDIA Corporation (Santa Clara, California) |
INVENTOR(S) | Hanrui Wang (Cambridge, Massachusetts); James Michael O'Connor (Austin, Texas); Donghyuk Lee (Cedar Park, Texas) |
ABSTRACT | One embodiment sets forth a technique for performing one or more matrix multiplication operations based on a first matrix and a second matrix. The technique includes receiving data associated with the first matrix from a first traversal engine that accesses nonzero elements included in the first matrix via a first tree structure. The technique also includes performing one or more computations on the data associated with the first matrix and the data associated with the second matrix to produce a plurality of partial results. The technique further includes combining the plurality of partial results into one or more intermediate results and storing the one or more intermediate results in a first buffer memory. |
FILED | Wednesday, May 19, 2021 |
APPL NO | 17/325120 |
ART UNIT | 2182 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 9/5072 (20130101) G06F 16/9027 (20190101) G06F 17/16 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141657 | Figgatt et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); IonQ, Inc. (College Park, Maryland) |
ASSIGNEE(S) | IonQ, Inc. (College Park, Maryland); University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | Caroline Figgatt (Denver, Colorado); Aaron Ostrander (Woodstock, Georgia); Norbert M. Linke (Stevenson, Maryland); Kevin A. Landsman (Rockville, Maryland); Daiwei Zhu (College Park, Maryland); Dmitri Maslov (Falls Church, Virginia); Christopher Monroe (Columbia, Maryland) |
ABSTRACT | The disclosure describes various aspects related to enabling effective multi-qubit operations, and more specifically, to techniques for enabling parallel multi-qubit operations on a universal ion trap quantum computer. In an aspect, a method of performing quantum operations in an ion trap quantum computer or trapped-ion quantum system includes implementing at least two parallel gates of a quantum circuit, each of the at least two parallel gates is a multi-qubit gate, each of the at least two parallel gates is implemented using a different set of ions of a plurality of ions in a ion trap, and the plurality of ions includes four or more ions. The method further includes simultaneously performing operations on the at least two parallel gates as part of the quantum operations. A trapped-ion quantum system and a computer-readable storage medium corresponding to the method described above are also disclosed. |
FILED | Friday, April 28, 2023 |
APPL NO | 18/309486 |
ART UNIT | 2182 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 7/501 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141660 | Jiang et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Liang Jiang (Chicago, Illinois); Filip D. Rozpedek (Chicago, Illinois); Kyungjoo Noh (Pasadena, California) |
ABSTRACT | Quantum repeaters and network architectures use two concatenated quantum error correction codes to increase the transmission range of quantum information. A block of data qubits collectively encode a second-layer logical qubit according to a second-layer code concatenated with a first-layer code. A first-layer quantum repeater first-layer corrects each data qubit based on a first-layer syndrome extracted therefrom. The first-layer quantum repeater transmits these first-layer-corrected qubits to a second-layer quantum repeater via a quantum communication channel. The first-layer quantum repeater also transmits the first-layer syndromes to the second-layer quantum repeater via a classical communication channel. After extracting a second-layer syndrome from the first-layer-corrected qubits, the second-layer quantum repeater uses the first-layer syndromes and second-layer syndrome to second-layer correct the first-layer-corrected qubits. The first-layer syndromes improve quantum error correction by reducing the number of sec-and-layer stabilizer measurements needed to determine which data qubits have an error. |
FILED | Friday, June 04, 2021 |
APPL NO | 18/000074 |
ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/70 (20220101) Original (OR) Class Transmission H04B 10/70 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141680 | Fink et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Yoel Fink (Brookline, Massachusetts); Gabriel Zi Jie Loke (Cambridge, Massachusetts); Tural Khudiyev (Revere, Massachusetts) |
ABSTRACT | A fiber computer has a fiber body including electrically insulating fiber body material along the length of the fiber body. Electrical conductors are disposed within the fiber body and are operative to transmit electrical power, electrical ground, clock signals, and data signals through the fiber body. Input units disposed within the fiber body accept external stimuli. Microcontroller microchips disposed within the fiber body process stimuli accepted by an input unit. Memory module microchips within the fiber body store data and communicate with microcontroller microchips. Output units produce an output directed out of the fiber body. A clock signal generator within the fiber body synchronizes operation of input units, microcontroller microchips, memory module microchips, and output units. Each of the computer input units, microcontroller microchips, memory module microchips, and computer output units are disposed in electrical connection with the plurality of electrical conductors for fiber computer operation within the fiber body. |
FILED | Friday, October 30, 2020 |
APPL NO | 17/086154 |
ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) Woven Fabrics; Methods of Weaving; Looms D03D 1/0088 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/18 (20130101) D10B 2403/02431 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) G06N 3/08 (20130101) G06N 3/063 (20130101) Original (OR) Class Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 3/30 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/08 (20130101) H04R 1/028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141697 | Chu et al. |
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FUNDED BY |
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APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
INVENTOR(S) | Linsong Chu (White Plains, New York); Pranita Sharad Dewan (White Plains, New York); Raghu Kiran Ganti (Elmsford, New York); Joshua M. Rosenkranz (Westchester, New York); Mudhakar Srivatsa (White Plains, New York) |
ABSTRACT | Aspects of the present disclosure relate to annotating or tagging customer data. In some embodiments, the annotating can include summarizing touchpoints into k-hot encoding feature vectors, mapping the feature vectors onto an embedding layer, predicting a hierarchical data sequence using the embedding layer and the feature vectors, extracting the feature vectors that are most influential in predicting the embedding layer, and outputting the touchpoints associated with the most influential feature vectors. |
FILED | Tuesday, April 18, 2023 |
APPL NO | 18/302255 |
ART UNIT | 2156 — Data Bases & File Management |
CURRENT CPC | Electric Digital Data Processing G06F 16/282 (20190101) G06F 16/285 (20190101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141878 | Shu et al. |
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FUNDED BY |
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APPLICANT(S) | Kai Shu (Mesa, Arizona); Deepak Mahudeswaran (Tempe, Arizona); Huan Liu (Tempe, Arizona) |
ASSIGNEE(S) | |
INVENTOR(S) | Kai Shu (Mesa, Arizona); Deepak Mahudeswaran (Tempe, Arizona); Huan Liu (Tempe, Arizona) |
ABSTRACT | Detecting fake news involves receiving a plurality of allegedly real news stories and allegedly fake news stories from one or more websites, receiving a plurality of user posts to a social media platform relating to the plurality of allegedly real news stories and allegedly fake news stories; receiving a plurality of user engagements related to the plurality of user posts, receiving user profile information, and social media network information, for users creating the plurality of user posts to the social media platform, and users participating in the engagements related to the plurality of user posts, and classifying each of the received plurality of allegedly real news stories and allegedly fake news stories as one of a real news story and a fake news story based on the analyzed content and analyzed social media context. |
FILED | Monday, September 23, 2019 |
APPL NO | 17/267765 |
ART UNIT | 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0201 (20130101) G06Q 50/01 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142098 | Vemury et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Arun R. Vemury (North Bethesda, Maryland); Yevgeniy B. Sirotin (Severna Park, Maryland); Cynthia M. Cook (Pittsburg, Pennsylvania); John J. Howard (Bethesda, Maryland); Jerry L. Tipton (Severn, Maryland) |
ABSTRACT | In examples, a relative skin reflectance of a captured image of a subject is quantified. Based on the relative skin reflectance, the captured image is determined as suitable or not suitable for biometric identification. When the captured image is determined not suitable, a remedial capture setting is calculated and provided to an image capturing resource. Another captured image of the subject, captured under the remedial capture setting, is received from the image capturing resource. The relative skin reflectance of the another captured image is quantified and based thereon, there is a determining of whether the another captured image is suitable or is not suitable. |
FILED | Thursday, January 11, 2024 |
APPL NO | 18/410616 |
ART UNIT | 2488 — Recording and Compression |
CURRENT CPC | Image or Video Recognition or Understanding G06V 10/141 (20220101) G06V 40/161 (20220101) G06V 40/162 (20220101) G06V 40/166 (20220101) G06V 40/168 (20220101) G06V 40/172 (20220101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 9/00563 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 23/71 (20230101) H04N 23/74 (20230101) H04N 23/76 (20230101) H04N 23/611 (20230101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142104 | Yin et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Peng Yin (Cambridge, Massachusetts); Jocelyn Yoshiko Kishi (Cambridge, Massachusetts); Thomas E. Schaus (Cambridge, Massachusetts); Youngeun Kim (Cambridge, Massachusetts) |
ABSTRACT | Provided herein, in some embodiments, are molecular authentication methods, systems, and compositions. |
FILED | Thursday, March 21, 2019 |
APPL NO | 17/040041 |
ART UNIT | 3637 — Static Structures, Supports and Furniture |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6813 (20130101) C12Q 2563/185 (20130101) Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing G07D 7/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142153 | Drexler et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
INVENTOR(S) | Kyle Robert Drexler (San Diego, California); Stephen Hammel (Lakeside, California); John Stephen deGrassie (San Diego, California); Benjamin Joel Laxton (San Diego, California) |
ABSTRACT | A light-guided vehicle comprising: a platform; an optical sensor mounted to the platform, wherein the optical sensor is configured to image off-axis scatter of a photon beam; a processing unit mounted to the platform, wherein the processing unit is communicatively coupled to the platform and to the optical sensor, and wherein the processing unit is configured to monitor intensities of off-axis photons that are scattered by aerosol particles in a beam propagation path as measured by the optical sensor, and wherein the processing unit is further configured to maintain the platform within a vehicle path based on the monitored off-axis-photon intensities, wherein the vehicle path is offset from, and parallel to, the propagation path. |
FILED | Thursday, December 22, 2022 |
APPL NO | 18/087503 |
ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Image or Video Recognition or Understanding G06V 20/17 (20220101) Traffic Control Systems G08G 5/0069 (20130101) Original (OR) Class G08G 5/0091 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142177 | Moulton, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | JRM Enterprises, Inc. (Orlando, Florida) |
ASSIGNEE(S) | JRM Enterprises, Inc. (Orlando, Florida) |
INVENTOR(S) | J. Russ Moulton, Jr. (Orlando, Florida); Steve Butrimas (Orlando, Florida); Christopher Fink (Orlando, Florida); Dan Bybee (Orlando, Florida); Isaac Ehlers (Orlando, Florida); William Hilton (Orlando, Florida) |
ABSTRACT | A dynamic infrared (IR) scene generation system comprising a thin-film screen configured to react to contact by an IR laser; a laser scanning system configured to contact the thin-film screen with laser beam, the laser scanning system comprising a laser scanner, one or more modulators, and an IR laser source; and an image processing system operably connected to a controller configured to control the laser scanning system based on data from the image processing system, wherein the laser scanning system can be configured to contact the thin-film screen with the IR laser based on an IR scene input. |
FILED | Wednesday, August 09, 2023 |
APPL NO | 18/447106 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Weapon Sights; Aiming F41G 3/165 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 2005/0077 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142473 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | Duke University (Durham, North Carolina) |
ASSIGNEE(S) | Duke University (Durham, North Carolina) |
INVENTOR(S) | Jungsang Kim (Chapel Hill, North Carolina); Kai Hudek (Durham, North Carolina); Geert Vrijsen (Durham, North Carolina); Robert Spivey (Durham, North Carolina); Peter Maunz (Durham, North Carolina) |
ABSTRACT | A package-level, integrated high-vacuum ion-chip enclosure having improved thermal characteristics is disclosed. Enclosures in accordance with the present invention include first and second chambers that are located on opposite sides of a chip carrier, where the chambers are fluidically coupled via a conduit through the chip carrier. The ion trap is located in the first chamber and disposed on the chip carrier. A source for generating an atomic flux is located in the second chamber. The separation of the source and ion trap in different chambers affords thermal isolation between them, while the conduit between the chambers enables the ion trap to receive the atomic flux. |
FILED | Tuesday, July 18, 2023 |
APPL NO | 18/223246 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Electric Discharge Tubes or Discharge Lamps H01J 49/16 (20130101) H01J 49/24 (20130101) H01J 49/42 (20130101) H01J 49/422 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142836 | Hamza et al. |
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FUNDED BY |
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APPLICANT(S) | Muhammad Hamza (Miami, Florida); Stavros Georgakopoulos (Miami, Florida); Constantinos L. Zekios (Miami, Florida) |
ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
INVENTOR(S) | Muhammad Hamza (Miami, Florida); Stavros Georgakopoulos (Miami, Florida); Constantinos L. Zekios (Miami, Florida) |
ABSTRACT | Ultra-wideband (UWB) arrays that are fully planar are provided. Fully-planar inverted-L element (FILE) arrays that are tightly coupled arrays (TCAs) can realize UWB tightly coupled apertures in the W and higher millimeter wave (mmWave) bands. The unit cell architecture of the FILE array, (which can have any desired size, can be comprised of an inverted-L shaped antenna and a capacitively coupled via-fence. |
FILED | Wednesday, May 10, 2023 |
APPL NO | 18/315006 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/405 (20130101) H01Q 5/25 (20150115) H01Q 9/42 (20130101) H01Q 21/0006 (20130101) H01Q 21/061 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142846 | Kaddour et al. |
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FUNDED BY |
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APPLICANT(S) | Abdul-Sattar Kaddour (Miami, Florida); Stavros Georgakopoulos (Miami, Florida) |
ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
INVENTOR(S) | Abdul-Sattar Kaddour (Miami, Florida); Stavros Georgakopoulos (Miami, Florida) |
ABSTRACT | Antenna arrays with three-dimensional (3D) conformal radiating elements are provided, as well as methods of manufacturing and methods of using the same. An array can include a ground plane and a plurality of unit cells disposed thereon. Each unit cell can include a 3D conformal radiating element. The 3D conformal radiating elements can be, for example, patches (e.g., circular 3D patches), dipoles, or loops, and each radiating element is conformal on a hemispherical shape. |
FILED | Tuesday, December 05, 2023 |
APPL NO | 18/529732 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/46 (20130101) H01Q 5/48 (20150115) Original (OR) Class H01Q 15/04 (20130101) H01Q 21/26 (20130101) H01Q 21/062 (20130101) H01Q 21/065 (20130101) H01Q 21/0087 (20130101) H01Q 21/205 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142850 | Hamza et al. |
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FUNDED BY |
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APPLICANT(S) | Muhammad Hamza (Miami, Florida); Stavros Georgakopoulos (Miami, Florida); Constantinos L. Zekios (Miami, Florida); Christos Exadaktylos (Miami, Florida) |
ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
INVENTOR(S) | Muhammad Hamza (Miami, Florida); Stavros Georgakopoulos (Miami, Florida); Constantinos L. Zekios (Miami, Florida); Christos Exadaktylos (Miami, Florida) |
ABSTRACT | Dual-polarized ultrawideband antennas and antenna arrays are provided. Fully inverted-L elements (FILEs) can be used as the radiating element in a unit cell antenna, which can be repeated to form an array. The dual-polarized FILE unit cell can include two L-bent elements, which tightly couple to a common shorted via as well as to each other. The same shorted via can be utilized to suppress the well-known common mode resonance. |
FILED | Wednesday, May 29, 2024 |
APPL NO | 18/677234 |
ART UNIT | 2845 — Electrical Circuits and Systems |
CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/48 (20130101) H01Q 5/25 (20150115) H01Q 9/0421 (20130101) Original (OR) Class H01Q 21/24 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12143134 | Haas et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Navy (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
INVENTOR(S) | Bryan Haas (Arnold, Maryland); Jason McKinney (Bowie, Maryland) |
ABSTRACT | Methods and apparatuses for downconverting high frequency subbands to a lower frequency band and recovering signals-of-interest. The system includes a controller, a signal generator, an optical source, a dual-drive mach zehnder modulator (DDMZM), a photodetector, and a dechipping/image (DI) rejector. The controller outputs chipping frequencies to the signal generator which generates local oscillator (LO) tones shifted by the respective chipping frequencies. The optical source outputs an optical signal to the DDMZM which has first and second arms and modulators. The first modulator receives a signal from a source and modulates it onto the optical signal propagating through the first arm to form a first modulated optical signal. The second modulator receives the shifted local oscillator tones and modulates them onto the optical signal propagating through the second arm to form a second modulated optical signal. The DDMZM outputs a signal which is a combination of the first and second modulated optical signals to the photodetector which generates a corresponding electrical signal. The dechipping/image (DI) rejector receives the electrical signal and one of the chipping frequencies and outputs a signal that maximizes signals in one high frequency subband while suppressing signals in other high frequency subbands. |
FILED | Friday, September 30, 2022 |
APPL NO | 17/958276 |
ART UNIT | 2632 — Digital Communications |
CURRENT CPC | Transmission H04B 1/1036 (20130101) Original (OR) Class H04B 10/505 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12143406 | Powell et al. |
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FUNDED BY |
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APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
INVENTOR(S) | Makia S Powell (North Dighton, Massachusetts); Benjamin M Drozdenko (Newport, Rhode Island); Steven A Roodbeen (Seekonk, Massachusetts) |
ABSTRACT | A method for detecting a cyberattack is provided. A set of packet capture training data has data elements labeled as being normal or cyberattack data. Metrics in the data are identified that are associated with either cyberattack data or normal data. Statistical measures are developed from these metrics. The training data and statistical measures are used to train a machine learning network. Real packet capture data is obtained and statistical measures are developed for this real data. The trained machine learning network, real data and real statistical measures are utilized to classify the real data as cyberattack data or normal data. Users are alerted if the trained machine learning data identifies cyberattack data in the real packet capture data. |
FILED | Thursday, September 01, 2022 |
APPL NO | 17/900982 |
ART UNIT | 2451 — Computer Networks |
CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12144011 | Zhu et al. |
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FUNDED BY |
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APPLICANT(S) | SILVUS TECHNOLOGIES, INC. (Los Angeles, California) |
ASSIGNEE(S) | SILVUS TECHNOLOGIES, INC. (Los Angeles, California) |
INVENTOR(S) | Weijun Zhu (Los Angeles, California); Ajit Warrier (Los Angeles, California); Mansour Rachid (Los Angeles, California) |
ABSTRACT | A wireless communication system may include a plurality of nodes that use a medium access control (MAC) protocol to communicate over a shared medium or a primary channel. The MAC protocol may include a non-transmitting state during which one or more nodes are silent in the primary channel while two nodes in the wireless communication system are in communicating over the primary channel. Systems and methods described herein use medium access protocol (MAC) underlay signaling, which may include measuring or sensing availability for spectrum or transmitting data without the loss of network throughput over a secondary channel in a wireless communications system. In some embodiments, the systems and methods described herein use dynamic spectrum access (DSA) protocols to switch the channel of communication in the wireless communication system. |
FILED | Friday, February 07, 2020 |
APPL NO | 16/784964 |
ART UNIT | 2644 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Wireless Communication Networks H04W 16/14 (20130101) H04W 72/541 (20230101) Original (OR) Class H04W 80/02 (20130101) H04W 88/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12144264 | Shabani et al. |
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FUNDED BY |
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APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
ASSIGNEE(S) | New York University (New York, New York) |
INVENTOR(S) | Javad Shabani (Briarcliff Manor, New York); Kasra Sardashti (Brooklyn, New York) |
ABSTRACT | A method of fabricating a superconducting-semiconducting stack includes cleaning a surface of a substrate, the substrate comprising a group IV element; depositing an insulating buffer layer onto the substrate, the insulating buffer layer comprising the group IV element; depositing a p-doped layer onto the insulating buffer layer; depositing a diffusion barrier onto the p-doped layer; and processing the superconducting-semiconducting stack through dopant activation. |
FILED | Monday, January 09, 2023 |
APPL NO | 18/094706 |
ART UNIT | 2896 — Electrical Circuits and Systems |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Electric solid-state devices not otherwise provided for H10N 60/12 (20230201) Original (OR) Class H10N 60/128 (20230201) H10N 60/805 (20230201) H10N 60/0884 (20230201) H10N 60/0912 (20230201) |
VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
US 12138214 | Walsh et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Conor J. Walsh (Cambridge, Massachusetts); Ciaran O'Neill (Cambridge, Massachusetts); Nathan Phipps (Somerville, Massachusetts) |
ABSTRACT | A textile actuator and harness system can include a harness configured to be worn with a portion extending across a wearer's joint. The harness comprises a substantially inextensible section and at least two mounting locations spaced for positioning across the joint, with at least one located along the substantially inextensible section of the harness. A textile envelope defines a chamber and is made fluid-impermeable by (a) a fluid-impermeable bladder contained in the textile envelope and/or (b) a fluid-impermeable structure incorporated into the textile envelope. The textile envelope is secured to the harness at each mounting location, and the textile envelope has a pre-determined geometry configured to produce assistance to the joint due to inflation of the textile envelope during a relative increase in pressure inside the chamber. |
FILED | Wednesday, December 04, 2019 |
APPL NO | 17/298728 |
ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
CURRENT CPC | Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/0281 (20130101) A61H 3/00 (20130101) Original (OR) Class A61H 2201/1238 (20130101) A61H 2201/1409 (20130101) A61H 2201/1638 (20130101) A61H 2201/1652 (20130101) A61H 2201/1659 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) B25J 9/14 (20130101) Systems Acting by Means of Fluids in General; Fluid-pressure Actuators, e.g Servomotors; Details of Fluid-pressure Systems, Not Otherwise Provided for F15B 15/02 (20130101) F15B 15/10 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138366 | Zlotnick et al. |
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FUNDED BY |
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APPLICANT(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Hannah M. Zlotnick (Philadelphia, Pennsylvania); Andrew Todd Clark (North Wales, Pennsylvania); Robert L. Mauck (Philadelphia, Pennsylvania); Xuemei Cheng (Bryn Mawr, Pennsylvania) |
ABSTRACT | The present disclosure is concerned with magneto-patterned cell-laden hydrogel materials and methods of making and using those materials. The disclosed materials are useful for, among other things, repair of tissue defects, e.g., tissue at a tissue interface such as a bone-cartilage interface. |
FILED | Tuesday, April 13, 2021 |
APPL NO | 17/229829 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/042 (20130101) A61L 27/045 (20130101) A61L 27/46 (20130101) A61L 27/047 (20130101) A61L 27/52 (20130101) A61L 27/222 (20130101) A61L 27/225 (20130101) A61L 27/3847 (20130101) Original (OR) Class A61L 27/3852 (20130101) A61L 2300/41 (20130101) A61L 2300/43 (20130101) A61L 2300/258 (20130101) A61L 2300/402 (20130101) A61L 2300/406 (20130101) A61L 2300/408 (20130101) A61L 2300/414 (20130101) A61L 2300/426 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138369 | Nuxoll et al. |
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FUNDED BY |
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APPLICANT(S) | University of Iowa Research Foundation (Iowa City, Iowa) |
ASSIGNEE(S) | University of lowa Research Foundation (lowa City, Iowa) |
INVENTOR(S) | Eric Nuxoll (Iowa City, Iowa); Joel Coffel (Iowa City, Iowa); Erica Ricker (Iowa City, Iowa) |
ABSTRACT | A system for disrupting a biofilm on a medical device that comprises an implantable medical device; a magnetically-sensitive coating on the surface of the implantable device comprising a polymer and magnetic particles embedded within the polymer; and a coil element capable of generating an alternating magnetic field, wherein the coil element is constructed and arranged to be capable of applying an alternating magnetic field to induce heating of the surface of the implantable device. |
FILED | Tuesday, June 27, 2017 |
APPL NO | 16/312680 |
ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/04 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0077 (20130101) A61F 7/00 (20130101) A61F 7/12 (20130101) A61F 7/123 (20130101) A61F 2007/126 (20130101) A61F 2210/009 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/00 (20130101) A61L 27/34 (20130101) A61L 27/50 (20130101) A61L 29/14 (20130101) A61L 29/085 (20130101) A61L 31/10 (20130101) A61L 31/14 (20130101) Original (OR) Class A61L 2400/18 (20130101) A61L 2420/06 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 2/002 (20130101) A61N 2/02 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138857 | Torabi et al. |
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FUNDED BY |
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APPLICANT(S) | 3DEO, Inc. (Torrance, California) |
ASSIGNEE(S) | 3DEO, Inc. (Torrance, California) |
INVENTOR(S) | Payman Torabi (Los Angeles, California); Matthew Petros (Tarzana, California) |
ABSTRACT | The present disclosure provides systems and methods for the formation of three-dimensional objects. A method for forming a three-dimensional object may comprise alternately and sequentially applying a stream comprising a binding substance to an area of a layer of powder material in a powder bed, and generating at least one perimeter of the three-dimensional object in the area. The stream may be applied in accordance with a model design of the three-dimensional object. The at least one perimeter may generated in accordance with the model design. |
FILED | Friday, April 28, 2023 |
APPL NO | 18/309121 |
ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/003 (20130101) B22F 3/24 (20130101) B22F 3/26 (20130101) B22F 3/1021 (20130101) B22F 10/00 (20210101) B22F 10/14 (20210101) B22F 10/14 (20210101) B22F 10/14 (20210101) B22F 10/32 (20210101) B22F 10/50 (20210101) B22F 10/66 (20210101) B22F 10/80 (20210101) B22F 12/10 (20210101) B22F 12/41 (20210101) B22F 12/45 (20210101) B22F 12/53 (20210101) B22F 2003/247 (20130101) B22F 2202/01 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/165 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/00 (20141201) B33Y 40/20 (20200101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139437 | Balapour et al. |
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FUNDED BY |
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APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
INVENTOR(S) | Mohammad Balapour (Philadelphia, Pennsylvania); Yaghoob Farnam (Philadelphia, Pennsylvania) |
ABSTRACT | Off-spec fly ash-based spherical lightweight aggregate (LWA), designated SPoRA, was manufactured and its engineering properties, including specific gravity, dry rodded unit weight, water absorption, mechanical performance, and pore structure, were evaluated. Using the characterized SPoRA, lightweight concrete (LWC) samples were made and properties of the LWC were assessed and compared with samples made using the traditional LWA. The results indicated that fine and coarse SPoRA had 72 h absorption capacities of 16.4% and 20.9%, respectively, which were higher than that of traditional LWA. SPoRA had a saturated surface dry (SSD) specific gravity higher than traditional LWA, which resulted in higher fresh density for the LWC prepared with SPoRA. Large spherical type pores were found for SPoRA similar to the traditional slate-based LWA. The pore size distribution of SPoRA, characterized using a dynamic vapor sorption analyzer, indicated that more than 97% of the pores had pore diameters greater than 50 nm. |
FILED | Tuesday, August 30, 2022 |
APPL NO | 17/899458 |
ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 18/08 (20130101) Original (OR) Class C04B 18/08 (20130101) C04B 18/027 (20130101) C04B 18/027 (20130101) C04B 18/082 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/91 (20150501) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139559 | Kim et al. |
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FUNDED BY |
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APPLICANT(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
INVENTOR(S) | Jin-Woo Kim (Fayetteville, Arkansas); Joseph Batta-Mpouma (Fayetteville, Arkansas); Joshua Sakon (Fayetteville, Arkansas) |
ABSTRACT | This invention relates generally to covalently crosslinked colloidal cellulose nanocrystals (xCNC) and methods of preparation and use thereof. The colloidal cellulose nanocrystals (CNCs) are covalently crosslinked in aqueous suspension to generate a network showing tunable physicochemical properties. The xCNC structures are tunable in terms of their physicochemical properties and arrangement within the hydrogel network. The covalent crosslinking of solitary sulfonated (—OSO3) CNCs can be accomplished without prior hydroxyl replacement or functionalization. |
FILED | Monday, September 20, 2021 |
APPL NO | 17/479053 |
ART UNIT | 1623 — Organic Chemistry |
CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Polysaccharides; Derivatives Thereof C08B 15/08 (20130101) C08B 15/10 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/07 (20130101) C08K 5/1515 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139723 | Stice et al. |
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FUNDED BY |
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APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia); Aruna Bio, Inc. (Athens, Georgia) |
ASSIGNEE(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia); ARUNA BIO, INC. (Athens, Georgia) |
INVENTOR(S) | Steven L. Stice (Athens, Georgia); Robin Lynn Webb (Winterville, Georgia); Tracey A. Stice (Athens, Georgia) |
ABSTRACT | Disclosed herein are neural extracellular vesicles (EVs) and methods of using these EVs in the treatment of spinal cord injury, stroke, and traumatic brain injury and neurodegenerative disease. |
FILED | Friday, April 23, 2021 |
APPL NO | 17/238760 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5068 (20130101) A61K 9/5176 (20130101) A61K 35/12 (20130101) A61K 35/30 (20130101) A61K 35/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 5/0622 (20130101) C12N 5/0623 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) C12N 2533/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139800 | Kuhn et al. |
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FUNDED BY |
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APPLICANT(S) | University of South Florida (Tampa, Florida) |
ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
INVENTOR(S) | John N. Kuhn (Wesley Chapel, Florida); Swetha Ramani (Tampa, Florida); Sadik Cogal (Lutz, Florida); Jeffrey Lowe (Pinedale, Wyoming); Venkat R. Bhethanabotla (Tampa, Florida) |
ABSTRACT | In one aspect, the disclosure relates to catalysts for electrochemical water splitting, in particular catalysts useful for oxygen evolution at an anode in electrochemical water splitting. The disclosed catalysts compositions comprise a catalyst core component, a shell component, and optionally a catalyst outer component; wherein the catalyst core component comprises a composition having the chemical formula MxPy; where M is a transition metal; wherein x is a number from about 1 to about 20; wherein y is a number from about 1 to about 20; wherein the shell component comprises a conducting polymer; and wherein the catalyst outer component is a transition metal that is not the same as the transition metal M. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
FILED | Tuesday, December 17, 2019 |
APPL NO | 17/414791 |
ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/057 (20210101) C25B 11/075 (20210101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139818 | Cera et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Luca Cera (Cambridge, Massachusetts); Kevin Kit Parker (Cambridge, Massachusetts) |
ABSTRACT | The present invention provides methods for preparing an alpha-keratin solution comprising alpha-keratin protofibrils and intermediate filaments in liquid crystal phase and uses thereof for fabricating, e.g., shape-memory polymeric fibers, yarns, threads, fabrics, structures and objects. |
FILED | Friday, July 26, 2019 |
APPL NO | 17/262318 |
ART UNIT | 1754 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 1/02 (20130101) Original (OR) Class D01D 5/06 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/00 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2211/02 (20130101) D10B 2401/046 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139821 | Liu et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Qihan Liu (Cambridge, Massachusetts); Kevin Kit Parker (Cambridge, Massachusetts); Huibin Chang (Cambridge, Massachusetts) |
ABSTRACT | Systems and methods for focused direction deposition of a micron or nanometer dimension polymeric fiber and materials of such fibers are described herein. Systems and methods employ one or more gas flows to entrain and deflect fibers produced by a rotary jet spinning system forming a focused fiber stream. Some embodiments enable control of alignment and distribution of the fibers with a relatively high fiber throughput. |
FILED | Tuesday, January 14, 2020 |
APPL NO | 17/421047 |
ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/14 (20130101) Original (OR) Class D01D 5/18 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140477 | Jarrahi et al. |
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FUNDED BY |
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APPLICANT(S) | The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
INVENTOR(S) | Mona Jarrahi (Los Angeles, California); Ning Wang (Mountain View, California) |
ABSTRACT | A system for detecting high-frequency radiation that offers near-quantum-limited sensitivity, broad spectral bandwidth, and high spectral resolution while operating at room temperature. The system can include an antenna assembly configured to receive at least a high-frequency radiation and a substrate comprising a semiconductor material with a contact-semiconductor interface connected to the antenna assembly. The system also includes an optical pump configured to produce an optical beam that has a high-frequency beat frequency, the optical beam contacting the contact-semiconductor interface to create an intermediate frequency signal by combining the optical beam with the high-frequency radiation. The system further includes a detector configured to detect the intermediate frequency and generate at least one report indicating the received, high-frequency radiation. |
FILED | Monday, April 01, 2019 |
APPL NO | 17/044486 |
ART UNIT | 2884 — Optics |
CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/4338 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 9/16 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140593 | Hughes et al. |
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FUNDED BY |
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APPLICANT(S) | Montana Molecular LLC (Bozeman, Montana) |
ASSIGNEE(S) | Montana Molecular LLC (Bozeman, Montana) |
INVENTOR(S) | Thomas E. Hughes (Bozeman, Montana); Paul H. Tewson (Bozeman, Montana); Anne Marie Quinn (Bozeman, Montana) |
ABSTRACT | Described herein are novel fluorescent sensors for cyclic adenosine monophosphate (cAMP) that are based on single fluorescent proteins. These sensors use less visible spectrum than FRET-based sensors, produce robust changes in fluorescence, and can be combined with one another, or with other sensors, in a multiplex assay on standard fluorescent plate readers or live cell imaging systems. |
FILED | Wednesday, May 25, 2022 |
APPL NO | 17/824643 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/00 (20130101) C07K 2319/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/566 (20130101) Original (OR) Class G01N 33/582 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140775 | Ünlü et al. |
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FUNDED BY |
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APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
INVENTOR(S) | M. Selim Ünlü (Newton, Massachusetts); Mete Aslan (Brighton, Massachusetts); Iris Celebi (Allston, Massachusetts); Celalettin Yurdakul (Santa Clara, California); Allison Marie Marn (Winchester, Massachusetts) |
ABSTRACT | An exemplary illumination source is provided. The illumination source includes a light integrating device for coupling to at least one optical structure at an output port. The light integrating device includes at least one input port. At least one light source produces at least one optical illumination coupled to the at least one input port. A light adjusting tool controls the optical illumination emitted by the light integrating device. The light adjusting tool controls uniformity of light emitted by the light integrating device by modifying at least one internal surface of the light integrating device. |
FILED | Wednesday, July 26, 2023 |
APPL NO | 18/226483 |
ART UNIT | 2872 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/08 (20130101) G02B 27/48 (20130101) G02B 27/0916 (20130101) G02B 27/0927 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140992 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
INVENTOR(S) | Hao Wang (Madison, Wisconsin); Nam Sung Kim (Middleton, Wisconsin) |
ABSTRACT | A computer architecture provides both a parallel memory bus and serial memory bus between a processor system and memory. Latency-tolerant memory access requests are steered to the serial memory bus which operates to increase the available memory bus bandwidth on the parallel memory. The invention also provides integrated circuit computer memory suitable for this application. |
FILED | Friday, August 04, 2023 |
APPL NO | 18/230418 |
ART UNIT | 2184 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 1/10 (20130101) Original (OR) Class G06F 3/0635 (20130101) G06F 13/16 (20130101) G06F 13/40 (20130101) G06F 13/42 (20130101) G06F 13/161 (20130101) G06F 13/1663 (20130101) G06F 13/1684 (20130101) G06F 13/4018 (20130101) G06F 13/4234 (20130101) G06F 13/4243 (20130101) G06F 2213/0038 (20130101) G06F 2213/0042 (20130101) G06F 2213/0064 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141508 | Agonafer |
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APPLICANT(S) | Damena Agonafer (St. Louis, Missouri) |
ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
INVENTOR(S) | Damena Agonafer (St. Louis, Missouri) |
ABSTRACT | System and methods for forming a micropillar array for an evaporative heat exchanger include selecting a preliminary shape for a micropillar, determining a droplet shape that is generated by the preliminary shape, and generating at least one curve that defines the droplet shape. The system and methods also include performing an evaporative simulation based on the curve and selecting a final micropillar shape based on the evaporative simulation. The system and methods further include fabricating an array of micropillars including at least one micropillar having the final micropillar shape. |
FILED | Tuesday, March 16, 2021 |
APPL NO | 17/203677 |
ART UNIT | 2146 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 30/23 (20200101) G06F 30/25 (20200101) Original (OR) Class G06F 30/28 (20200101) G06F 2113/08 (20200101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141657 | Figgatt et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); IonQ, Inc. (College Park, Maryland) |
ASSIGNEE(S) | IonQ, Inc. (College Park, Maryland); University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | Caroline Figgatt (Denver, Colorado); Aaron Ostrander (Woodstock, Georgia); Norbert M. Linke (Stevenson, Maryland); Kevin A. Landsman (Rockville, Maryland); Daiwei Zhu (College Park, Maryland); Dmitri Maslov (Falls Church, Virginia); Christopher Monroe (Columbia, Maryland) |
ABSTRACT | The disclosure describes various aspects related to enabling effective multi-qubit operations, and more specifically, to techniques for enabling parallel multi-qubit operations on a universal ion trap quantum computer. In an aspect, a method of performing quantum operations in an ion trap quantum computer or trapped-ion quantum system includes implementing at least two parallel gates of a quantum circuit, each of the at least two parallel gates is a multi-qubit gate, each of the at least two parallel gates is implemented using a different set of ions of a plurality of ions in a ion trap, and the plurality of ions includes four or more ions. The method further includes simultaneously performing operations on the at least two parallel gates as part of the quantum operations. A trapped-ion quantum system and a computer-readable storage medium corresponding to the method described above are also disclosed. |
FILED | Friday, April 28, 2023 |
APPL NO | 18/309486 |
ART UNIT | 2182 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 7/501 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141660 | Jiang et al. |
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FUNDED BY |
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APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
INVENTOR(S) | Liang Jiang (Chicago, Illinois); Filip D. Rozpedek (Chicago, Illinois); Kyungjoo Noh (Pasadena, California) |
ABSTRACT | Quantum repeaters and network architectures use two concatenated quantum error correction codes to increase the transmission range of quantum information. A block of data qubits collectively encode a second-layer logical qubit according to a second-layer code concatenated with a first-layer code. A first-layer quantum repeater first-layer corrects each data qubit based on a first-layer syndrome extracted therefrom. The first-layer quantum repeater transmits these first-layer-corrected qubits to a second-layer quantum repeater via a quantum communication channel. The first-layer quantum repeater also transmits the first-layer syndromes to the second-layer quantum repeater via a classical communication channel. After extracting a second-layer syndrome from the first-layer-corrected qubits, the second-layer quantum repeater uses the first-layer syndromes and second-layer syndrome to second-layer correct the first-layer-corrected qubits. The first-layer syndromes improve quantum error correction by reducing the number of sec-and-layer stabilizer measurements needed to determine which data qubits have an error. |
FILED | Friday, June 04, 2021 |
APPL NO | 18/000074 |
ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/70 (20220101) Original (OR) Class Transmission H04B 10/70 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141680 | Fink et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Yoel Fink (Brookline, Massachusetts); Gabriel Zi Jie Loke (Cambridge, Massachusetts); Tural Khudiyev (Revere, Massachusetts) |
ABSTRACT | A fiber computer has a fiber body including electrically insulating fiber body material along the length of the fiber body. Electrical conductors are disposed within the fiber body and are operative to transmit electrical power, electrical ground, clock signals, and data signals through the fiber body. Input units disposed within the fiber body accept external stimuli. Microcontroller microchips disposed within the fiber body process stimuli accepted by an input unit. Memory module microchips within the fiber body store data and communicate with microcontroller microchips. Output units produce an output directed out of the fiber body. A clock signal generator within the fiber body synchronizes operation of input units, microcontroller microchips, memory module microchips, and output units. Each of the computer input units, microcontroller microchips, memory module microchips, and computer output units are disposed in electrical connection with the plurality of electrical conductors for fiber computer operation within the fiber body. |
FILED | Friday, October 30, 2020 |
APPL NO | 17/086154 |
ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 1/10 (20130101) Woven Fabrics; Methods of Weaving; Looms D03D 1/0088 (20130101) Indexing Scheme Associated With Sublasses of Section D, Relating to Textiles D10B 2401/18 (20130101) D10B 2403/02431 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) G06N 3/08 (20130101) G06N 3/063 (20130101) Original (OR) Class Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 3/30 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/08 (20130101) H04R 1/028 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141963 | Metzger et al. |
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FUNDED BY |
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APPLICANT(S) | THE ROCKEFELLER UNIVERSITY (New York, New York) |
ASSIGNEE(S) | THE ROCKEFELLER UNIVERSITY (New York, New York) |
INVENTOR(S) | Jakob Metzger (New York, New York); Fred Etoc (New York, New York); Ali Brivanlou (New York, New York); Eric Siggia (New York, New York) |
ABSTRACT | Systems and methods for identifying molecules that are biologically active against a disease, where the method can comprise culturing a first mammalian cell population under organoid formation conditions in the presence of a test molecule to obtain a first organoid, wherein the first mammalian cell population, when cultured under the organoid formation conditions in the absence of the test molecule, results in an organoid with a disease phenotype; imaging the first organoid following exposure to the test molecule; analyzing one or more images of the first organoid using a neural network that has been trained to assign a probability score of disease or non-disease ranging between 0% and 100%; assigning the first organoid a probability score ranging between 0% and 100%; wherein the test molecule is biologically active against the disease if the probability score of the first organoid is greater than a cutoff probability score of non-disease or lower than a cutoff probability score of disease. |
FILED | Friday, October 04, 2019 |
APPL NO | 17/282039 |
ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 2503/02 (20130101) C12N 2510/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 33/5014 (20130101) G01N 33/5076 (20130101) Electric Digital Data Processing G06F 18/214 (20230101) G06F 18/217 (20230101) Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2200/04 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) G06T 2207/30072 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/764 (20220101) G06V 20/698 (20220101) G06V 2201/03 (20220101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/00 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142104 | Yin et al. |
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FUNDED BY |
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APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
INVENTOR(S) | Peng Yin (Cambridge, Massachusetts); Jocelyn Yoshiko Kishi (Cambridge, Massachusetts); Thomas E. Schaus (Cambridge, Massachusetts); Youngeun Kim (Cambridge, Massachusetts) |
ABSTRACT | Provided herein, in some embodiments, are molecular authentication methods, systems, and compositions. |
FILED | Thursday, March 21, 2019 |
APPL NO | 17/040041 |
ART UNIT | 3637 — Static Structures, Supports and Furniture |
CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6813 (20130101) C12Q 2563/185 (20130101) Handling of Coins or Valuable Papers, e.g Testing, Sorting by Denominations, Counting, Dispensing, Changing or Depositing G07D 7/14 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
US 12138599 | Hopkinson et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Columbus, Ohio) |
ASSIGNEE(S) | Battelle Memorial Institute (Columbus, Ohio) |
INVENTOR(S) | David Philip Hopkinson (Morgantown, West Virginia); Lingxiang Zhu (Bethel Park, Pennsylvania) |
ABSTRACT | The present invention provides highly permeable and porous polybenzimidazole membranes, methods of making them, and their application as a high-performance membrane support for gas separation composite membranes. The polybenzimidazole membranes are bonded to a fabric substrate. |
FILED | Friday, July 16, 2021 |
APPL NO | 17/378632 |
ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
CURRENT CPC | Separation B01D 53/228 (20130101) B01D 67/0013 (20130101) B01D 67/0016 (20130101) B01D 67/0095 (20130101) B01D 69/02 (20130101) B01D 69/105 (20130101) B01D 69/122 (20130101) B01D 71/62 (20130101) Original (OR) Class B01D 2325/04 (20130101) B01D 2325/20 (20130101) B01D 2325/025 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138687 | Guillen et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
INVENTOR(S) | Donna P. Guillen (Idaho Falls, Idaho); Robert V. Fox (Idaho Falls, Idaho); Dennis S. Tucker (Idaho Falls, Idaho); Troy B. Holland (New Albany, Indiana) |
ABSTRACT | A method of forming an article comprises forming a feed material around one or more shapeholders and sintering the feed material and the one or more shapeholders to form a sintered article comprising the one or more shapeholders in a base material. The sintered article is exposed to a solvent to remove the one or more shapeholders from the base material. Additional methods are disclosed, as well as articles including one or more microchannels exhibiting a diameter of from about 5 μm to about 10 mm. |
FILED | Friday, October 13, 2023 |
APPL NO | 18/486790 |
ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/43 (20210101) B22F 10/62 (20210101) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138850 | Fenn et al. |
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FUNDED BY |
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APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
ASSIGNEE(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
INVENTOR(S) | David Robert Fenn (Allison Park, Pennsylvania); Kurt G. Olson (Gibsonia, Pennsylvania); Reza M. Rock (Pittsburgh, Pennsylvania); Cynthia Kutchko (Allison Park, Pennsylvania); Susan Donaldson (Allison Park, Pennsylvania); Anthony J. Fogl (Swissvale, Pennsylvania) |
ABSTRACT | Methods of additive manufacture using coreactive components are disclosed. Thermosetting compositions for additive manufacturing are also disclosed. |
FILED | Tuesday, November 10, 2020 |
APPL NO | 17/093886 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/10 (20200101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/10 (20130101) C08G 18/10 (20130101) C08G 18/325 (20130101) C08G 18/755 (20130101) C08G 18/792 (20130101) C08G 18/3234 (20130101) C08G 18/3821 (20130101) C08G 18/3855 (20130101) C08G 18/4854 (20130101) C08G 18/5024 (20130101) C08G 18/6685 (20130101) C08G 59/66 (20130101) C08G 75/14 (20130101) C08G 75/045 (20130101) C08G 2150/50 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/36 (20130101) C08K 3/36 (20130101) C08K 3/36 (20130101) C08K 3/046 (20170501) C08K 3/046 (20170501) Compositions of Macromolecular Compounds C08L 75/02 (20130101) C08L 81/02 (20130101) C08L 81/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 175/02 (20130101) C09D 175/04 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12138863 | Kelly et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Regents of the University of California (Oakland, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California); The Regents Of The University Of California (Oakland, California) |
INVENTOR(S) | Brett Kelly (Berkeley, California); Robert Matthew Panas (Dublin, California); Maxim Shusteff (Piedmont, California); Christopher Spadaccini (Oakland, California); Hayden Taylor (Berkeley, California); Indrasen Bhattacharya (Berkeley, California) |
ABSTRACT | In one aspect the present disclosure relates to a system for forming a three dimensional (3D) object from a volume of photo-responsive material contained within a material container. A plurality of optical projection subsystems are adapted to be arranged at least partially circumferentially around a material container containing the volume of photo-responsive material, and are controlled by a controller. The optical projection subsystems direct optical projections at a plurality of angles θ through the volume of photo-responsive material. The optical projections are further directed about a z axis extending through the volume of photo-responsive material. The plurality of optical subsystems are further controlled by the controller to provide each of the optical projections with a calculated three-dimensional intensity distribution acting over a fixed temporal exposure period, which is sufficient to at least one of cure or remove selected portions of the volume of photo-responsive material, and leave other portions unmodified, to form a desired 3D part. |
FILED | Friday, March 25, 2022 |
APPL NO | 17/704072 |
ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/129 (20170801) B29C 64/232 (20170801) B29C 64/241 (20170801) B29C 64/245 (20170801) B29C 64/264 (20170801) B29C 64/277 (20170801) B29C 64/393 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139617 | Lindsey et al. |
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FUNDED BY |
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APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
INVENTOR(S) | Jonathan S. Lindsey (Raleigh, North Carolina); Gongfang Hu (Cary, North Carolina); Rui Liu (Cary, North Carolina) |
ABSTRACT | Described herein are polymeric fluorophores that include a dye, a polymer, and optionally a bioconjugate group. A polymeric fluorophore may have a structure represented by: A-B-C or C-A-B, wherein A is a dye; B is a polymer comprising one or more hydrophobic unit(s) and one or more hydrophilic unit(s); and optionally C, wherein C, when present, comprises a bioconjugate group. Also described herein are compositions comprising the polymeric fluorophores and methods of preparing and using the same. |
FILED | Tuesday, December 18, 2018 |
APPL NO | 16/955152 |
ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) A61K 49/0054 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 293/005 (20130101) C08F 2438/03 (20130101) Compositions of Macromolecular Compounds C08L 33/08 (20130101) C08L 2207/53 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 69/108 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139738 | Kramer et al. |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Robert A. Kramer (Crown Point, Indiana); Libbie S. W. Pelter (Schererville, Indiana); John A. Patterson (West Lafayette, Indiana) |
ABSTRACT | Processes and systems for biologically producing hydrogen gas from organic waste, including food waste. Such a process includes biologically producing hydrogen gas from organic waste by anaerobic fermentation of the organic waste with at least one strain of yeast. |
FILED | Friday, September 25, 2020 |
APPL NO | 17/763761 |
ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/18 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 3/00 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139794 | Sandhage |
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FUNDED BY |
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APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
INVENTOR(S) | Kenneth H. Sandhage (Lafayette, Indiana) |
ABSTRACT | Methods of enhancing the corrosion resistance of an oxidizable material exposed to a supercritical fluid is disclosed One method includes placing a surface layer on an oxidizable material, and choosing a buffered supercritical fluid containing a reducing agent with the composition of the buffered supercritical fluid containing the reducing agent chosen to avoid the corrosion of the surface layer or reduce the rate of corrosion of the surface layer and avoid the corrosion of the oxidizable material or reduce the rate of corrosion of the oxidizable material at a temperature above the supercritical temperature and supercritical pressure of the supercritical fluid. |
FILED | Wednesday, October 11, 2017 |
APPL NO | 16/342597 |
ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 18/16 (20130101) C23C 18/18 (20130101) C23C 18/31 (20130101) C23C 18/32 (20130101) C23C 18/38 (20130101) C23C 18/48 (20130101) C23C 18/1603 (20130101) C23C 18/1635 (20130101) C23C 18/1637 (20130101) C23C 18/1646 (20130101) C23C 18/1685 (20130101) Original (OR) Class C23C 18/1803 (20130101) C23C 30/00 (20130101) C23C 30/005 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/1259 (20150115) Y10T 428/1266 (20150115) Y10T 428/1284 (20150115) Y10T 428/1291 (20150115) Y10T 428/12611 (20150115) Y10T 428/12618 (20150115) Y10T 428/12667 (20150115) Y10T 428/12806 (20150115) Y10T 428/12812 (20150115) Y10T 428/12819 (20150115) Y10T 428/12826 (20150115) Y10T 428/12833 (20150115) Y10T 428/12847 (20150115) Y10T 428/12854 (20150115) Y10T 428/12861 (20150115) Y10T 428/12882 (20150115) Y10T 428/12903 (20150115) Y10T 428/12917 (20150115) Y10T 428/12924 (20150115) Y10T 428/12931 (20150115) Y10T 428/12937 (20150115) Y10T 428/12944 (20150115) Y10T 428/12951 (20150115) Y10T 428/12972 (20150115) Y10T 428/12986 (20150115) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139815 | Franco et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Magdalena Franco (Livermore, California); Nicole Collette (Livermore, California); Patrik D'Haeseleer (Livermore, California) |
ABSTRACT | A newly developed generalizable screening method enables efficient identification of epitopes, in the proteomes of pathogenic agent is provided. Also disclosed are systems that enable the method as well as epitopes discovered using the method. |
FILED | Thursday, January 27, 2022 |
APPL NO | 17/586687 |
ART UNIT | 1675 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
CURRENT CPC | Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) Original (OR) Class C40B 40/10 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/30 (20190201) G16B 40/20 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140050 | MacDonald et al. |
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FUNDED BY |
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APPLICANT(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
ASSIGNEE(S) | RTX CORPORATION (Farmington, Connecticut) |
INVENTOR(S) | Malcolm P. MacDonald (Bloomfield, Connecticut); Stephen H. Taylor (East Hartford, Connecticut); Ram Ranjan (West Hartford, Connecticut) |
ABSTRACT | A gas turbine engine includes a core engine that includes a core flow path that connects a compressor section, combustor section and a turbine section. The gas turbine engine further includes a bottoming cycle system that includes a supercritical CO2 (sCO2) working fluid flow. A first recuperator is disposed in the core flow path downstream of the turbine section, the first recuperator is configured to transfer thermal energy from a core flow aft of the turbine section to the sCO2 working fluid flow. A second recuperator is disposed in the compressor section, the second recuperator is configured to transfer thermal energy from the sCO2 working fluid flow to a location forward of the combustor section. |
FILED | Tuesday, February 14, 2023 |
APPL NO | 18/109448 |
ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
CURRENT CPC | Steam Engine Plants; Steam Accumulators; Engine Plants Not Otherwise Provided For; Engines Using Special Working Fluids or Cycles F01K 23/10 (20130101) Original (OR) Class F01K 25/103 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/76 (20130101) F05D 2260/211 (20130101) F05D 2260/213 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140382 | Henry |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
INVENTOR(S) | Asegun Henry (Boston, Massachusetts) |
ABSTRACT | Energy storage systems are disclosed. The systems may store energy as heat in a high temperature liquid, and the heat may be converted to electricity by absorbing radiation emitted from the high temperature liquid via one or more photovoltaic devices when the high temperature liquid is transported through an array of conduits. Some aspects described herein relate to reducing deposition of sublimated material from the conduits onto the photovoltaic devices. |
FILED | Thursday, October 14, 2021 |
APPL NO | 17/501979 |
ART UNIT | 1721 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Methods of Steam Generation; Steam Boilers F22B 1/006 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/021 (20130101) Original (OR) Class F28D 2020/0082 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 10/30 (20141201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140645 | Romano et al. |
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FUNDED BY |
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APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
INVENTOR(S) | Joshua Romano (Albuquerque, New Mexico); Thomas M. Rice (Albuquerque, New Mexico); Stephen Neidigk (Albuquerque, New Mexico); Michael Bolduc (Albuquerque, New Mexico); Elijah David Hammond (Rio Rancho, New Mexico) |
ABSTRACT | A magnetic electrical latch assembly for sensing an electrical contact has a housing for supporting a magnetic electrical contact. The housing has an annular cavity and a cylinder disposed within the cavity. A magnetic electrical contact is attached at one end to the cylinder. The cylinder is movable axially within the cavity. The magnetic electrical contact has an electrical connection to a first conductive wire. The magnetic electrical contact is arranged to couple with an opposing contact pad to create an electrical connection between an external conductor path and the first conductive wire. Also, a magnetic electrical contact sensor system has a hollow enclosure with a detachable access panel. A meandering conductor path cover a portion of the access panel. The conductor path terminates on a contact pad. A magnetic electrical latch assembly has a housing for supporting the magnetic electrical contact within the enclosure. |
FILED | Wednesday, July 27, 2022 |
APPL NO | 17/874498 |
ART UNIT | 2689 — Signal Processing and Control Processing in Disk Drives |
CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/68 (20200101) Original (OR) Class Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/081 (20130101) H01F 2007/086 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140810 | Patra et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Susant K. Patra (Brentwood, California); Razi-Ul Muhammad Haque (San Francisco, California); Komal Kampasi (San Francisco, California); Ian Seth Ladner (Livermore, California) |
ABSTRACT | The present disclosure relates to a monolithic waveguide substrate for enabling routing of at least one optical signal. The monolithic waveguide substrate has a monolithic engineered substrate having a uniform material composition throughout, with a first index of refraction, and with a plurality of three-dimensional waveguides each being formed fully within an interior volume thereof by a corresponding plurality of three-dimensional waveguide channels. The three-dimensional waveguide channels are formed by wall portions each having a second index of refraction different from the first index of refraction. |
FILED | Friday, January 28, 2022 |
APPL NO | 17/587591 |
ART UNIT | 2874 — Optics |
CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/421 (20130101) G02B 6/4278 (20130101) G02B 6/4291 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140865 | Nam et al. |
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FUNDED BY |
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APPLICANT(S) | Brookhaven Science Associates, LLC (Upton, New York); The Board of Regents, The University of Texas System (Austin, Texas); The Research Foundation for the State University of New York (Albany, New York) |
ASSIGNEE(S) | Brookhaven Science Associates, LLC (Upton, New York); Board of Regents, The University of Texas System (Austin, Texas); The Research Foundation for The State University of New York (Albany, New York) |
INVENTOR(S) | Chang-Yong Nam (Stony Brook, New York); Aaron Stein (Huntington Station, New York); Ming Lu (Stony Brook, New York); Jiyoung Kim (Plano, Texas); Nikhil Tiwale (Medford, New York); Su Min Hwang (Plano, Texas); Ashwanth Subramanian (Stony Brook, New York) |
ABSTRACT | The present invention provides a method that utilizes an existing infrastructure such as atomic layer deposition or similar vapor-based deposition tool or metal salt solutions based infiltration to infiltrate certain metals or metal-based precursors into resist materials to enhance the performance of the resists for the advancement of lithography techniques. |
FILED | Wednesday, March 04, 2020 |
APPL NO | 16/808661 |
ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
CURRENT CPC | Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/2053 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/16 (20130101) Compositions of Macromolecular Compounds C08L 33/12 (20130101) C08L 39/08 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/407 (20130101) C23C 16/45525 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0042 (20130101) Original (OR) Class G03F 7/2004 (20130101) G03F 7/2043 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142642 | Varley et al. |
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FUNDED BY |
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APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
INVENTOR(S) | Joel Basile Varley (Livermore, California); Noah Patrick Allen (Oakland, California); Clint Frye (Livermore, California); Kyoung Eun Kweon (Pleasonton, California); Vincenzo Lordi (Livermore, California); Lars Voss (Livermore, California) |
ABSTRACT | An apparatus includes a heterostructure including a substrate of Group-III-nitride material, a source layer including a dopant positioned on a surface of the substrate, and a conductive cap layer positioned on the source layer. A method of electric field-enhanced impurity diffusion includes obtaining a heterostructure including a substrate of Group-III-nitride semiconductor material, a source layer including a dopant positioned directly on the substrate, and a conductive cap layer positioned above the source layer, and applying a thermal annealing treatment to the heterostructure. An electric field gradient is established within the source layer and the cap layer for causing diffusion of an element from the substrate to the cap layer, and for causing diffusion of the dopant from the source layer to a former location of the element in the substrate thereby changing a conductivity and/or magnetic characteristic of the substrate. |
FILED | Wednesday, February 03, 2021 |
APPL NO | 17/166962 |
ART UNIT | 2893 — Semiconductors/Memory |
CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/2258 (20130101) H01L 29/45 (20130101) H01L 29/2003 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142722 | Wang et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | Chunsheng Wang (Silver Spring, Maryland); Chongyin Yang (College Park, Maryland); Jijian Xu (Hyattsville, Maryland) |
ABSTRACT | The disclosure provides rechargeable lithium ion batteries comprising at least one lithium salt-graphite composite electrode. In particular, the disclosure provides a rechargeable “water-in-bisalt” lithium ion battery with a high potential where at least a portion of the lithium salt is phase separated from the aqueous electrolyte, and where the anionic-redox reaction occurs within the graphitic lattice. |
FILED | Friday, March 06, 2020 |
APPL NO | 17/436609 |
ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/043 (20130101) H01M 4/133 (20130101) H01M 4/364 (20130101) H01M 4/604 (20130101) H01M 4/623 (20130101) H01M 4/1393 (20130101) H01M 10/0525 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 2300/0085 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142754 | Wong et al. |
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FUNDED BY |
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APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
INVENTOR(S) | Stanislaus Wong (Upton, New York); Lei Wang (Port Jefferson, New York); Coray McBean (Malverne, New York); Amy C. Marschilok (Stony Brook, New York); Kenneth Takeuchi (Stony Brook, New York); Esther S. Takeuchi (Stony Brook, New York) |
ABSTRACT | A method of fabricating nanocomposite anode material embodying a lithium titanate (LTO)-multi-walled carbon nanotube (MWNT) composite intended for use in a lithium-ion battery includes providing multi-walled carbon nanotube (MWNTs), including nanotube surfaces, onto which functional oxygenated carboxylic acid moieties are arranged, generating 3D flower-like, lithium titanate (LTO) microspheres, including thin nanosheets and anchoring the acid-functionalized MWNTs onto surfaces of the 3D LTO microspheres by π-π interaction strategy to realize the nanocomposite anode material. |
FILED | Tuesday, July 06, 2021 |
APPL NO | 17/368252 |
ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/364 (20130101) Original (OR) Class H01M 4/366 (20130101) H01M 4/485 (20130101) H01M 4/523 (20130101) H01M 4/587 (20130101) H01M 4/624 (20130101) H01M 10/0525 (20130101) H01M 2004/021 (20130101) H01M 2004/027 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142800 | Wilson |
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FUNDED BY |
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APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
INVENTOR(S) | Mahlon Scott Wilson (Los Alamos, New Mexico) |
ABSTRACT | Various embodiments are directed to a passive pressure swing valve, a passive pressure swing system for fuel cell reactant recirculation, and methods of using the same. In various embodiments, a passive pressure swing system may comprise a reactant supply configured to dispense a volume of reactant fluid to a fluid flow path; a fuel cell configured to receive at least a portion of the volume of reactant fluid; a passive pressure swing valve arranged in-line with the fluid flow path; and a reservoir arranged in-line with the fluid flow path and configured to receive one or more of a portion of the volume of reactant fluid and a volume of byproduct water displaced from the fuel cell; wherein the fluid flow path is configured to deliver the volume of reactant fluid to one of an anode or a cathode of the fuel cell. |
FILED | Monday, June 28, 2021 |
APPL NO | 17/360554 |
ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/04104 (20130101) Original (OR) Class H01M 8/04164 (20130101) H01M 8/04783 (20130101) H01M 50/325 (20210101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12144100 | Tantawi et al. |
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FUNDED BY |
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APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
INVENTOR(S) | Sami G. Tantawi (Stanford, California); Emilio Nanni (Redwood City, California); Zenghai Li (Stanford, California); Cecile Limborg-Deprey (Palo Alto, California) |
ABSTRACT | A hadron therapy system that provides 3D scanning and rapid delivery of a high dose. Such systems can include a hadron source and accelerator with an RF energy modulator and an RF deflector that operate in combination to provide 3D scanning of a targeted tissue. The systems can include a permanent magnet quadrupole for magnification of the beam. The systems can include high energy hadron sources that utilize a multi-cell, multi-klystron design that achieves scanning of high energy hadron beams, for example a fixed energy of 200 MeV protons. Such systems can provide full irradiation of a liter scale tumor within one second or less. |
FILED | Friday, August 28, 2020 |
APPL NO | 17/006742 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1043 (20130101) A61N 5/1077 (20130101) A61N 2005/1087 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/001 (20130101) Original (OR) Class H05H 7/02 (20130101) H05H 7/04 (20130101) H05H 2007/025 (20130101) H05H 2007/045 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12144139 | Deng et al. |
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FUNDED BY |
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APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
INVENTOR(S) | Z. Daniel Deng (Richland, Washington); Jun Lu (Richland, Washington); Jayson J. Martinez (Kennewick, Washington); Aljon L. Salalila (Richland, Washington); Mitchell J. Myjak (Richland, Washington); Hongfei Hou (Richland, Washington) |
ABSTRACT | Methods for emulating interaction of entities within water systems are provided. The methods can include introducing a sensor assembly into a water system. The sensor assembly can include: a circuit board supporting processing circuitry components on either or both of opposing component support surfaces of the circuit board; a housing about the circuit board and the components, the housing being circular about the circuit board in at least one cross section; and wherein the support surfaces of the circuit board are substantially parallel with the plane of the housing in the one cross section. |
FILED | Thursday, November 03, 2022 |
APPL NO | 17/980077 |
ART UNIT | 2855 — Printing/Measuring and Testing |
CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 19/148 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0047 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/1427 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
US 12139027 | Pettey et al. |
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FUNDED BY |
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APPLICANT(S) | Response Technologies, LLC (Coventry, Rhode Island) |
ASSIGNEE(S) | RESPONSE TECHNOLOGIES, LLC (Coventry, Rhode Island) |
INVENTOR(S) | David Allen Pettey (Westport, Massachusetts); Edmund F. Bard (Cumberland, Rhode Island); Lao Vang (Providence, Rhode Island) |
ABSTRACT | A fuel cell containing fuel for an aircraft includes an innermost layer configured to contact the fuel, an outermost layer and a containment gel formed from isocyanate and polyol interposed between the innermost and outermost layers. The containment gel is configured to self-seal a ballistically formed hole therein, thereby reducing leakage of the fuel from the fuel cell. |
FILED | Tuesday, April 13, 2021 |
APPL NO | 17/228993 |
ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 1/00 (20130101) B32B 5/02 (20130101) B32B 7/12 (20130101) B32B 27/12 (20130101) B32B 27/40 (20130101) B32B 2250/40 (20130101) B32B 2307/762 (20130101) B32B 2439/40 (20130101) B32B 2605/18 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 50/75 (20190201) Original (OR) Class Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 37/06 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139539 | Wu |
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FUNDED BY |
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APPLICANT(S) | Cancure, LLC (Shoreline, Washington) |
ASSIGNEE(S) | CanCure, LLC (Shoreline, Washington) |
INVENTOR(S) | Jennifer Wu (Wilmette, Illinois) |
ABSTRACT | The present invention provides MIC antibodies, antigen binding portions thereof and MIC binding agents thereof for use in the treatment of cancer. |
FILED | Tuesday, October 25, 2022 |
APPL NO | 18/049434 |
ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2833 (20130101) Original (OR) Class C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140593 | Hughes et al. |
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FUNDED BY |
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APPLICANT(S) | Montana Molecular LLC (Bozeman, Montana) |
ASSIGNEE(S) | Montana Molecular LLC (Bozeman, Montana) |
INVENTOR(S) | Thomas E. Hughes (Bozeman, Montana); Paul H. Tewson (Bozeman, Montana); Anne Marie Quinn (Bozeman, Montana) |
ABSTRACT | Described herein are novel fluorescent sensors for cyclic adenosine monophosphate (cAMP) that are based on single fluorescent proteins. These sensors use less visible spectrum than FRET-based sensors, produce robust changes in fluorescence, and can be combined with one another, or with other sensors, in a multiplex assay on standard fluorescent plate readers or live cell imaging systems. |
FILED | Wednesday, May 25, 2022 |
APPL NO | 17/824643 |
ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
CURRENT CPC | Peptides C07K 14/00 (20130101) C07K 2319/60 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) G01N 33/566 (20130101) Original (OR) Class G01N 33/582 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141963 | Metzger et al. |
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FUNDED BY |
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APPLICANT(S) | THE ROCKEFELLER UNIVERSITY (New York, New York) |
ASSIGNEE(S) | THE ROCKEFELLER UNIVERSITY (New York, New York) |
INVENTOR(S) | Jakob Metzger (New York, New York); Fred Etoc (New York, New York); Ali Brivanlou (New York, New York); Eric Siggia (New York, New York) |
ABSTRACT | Systems and methods for identifying molecules that are biologically active against a disease, where the method can comprise culturing a first mammalian cell population under organoid formation conditions in the presence of a test molecule to obtain a first organoid, wherein the first mammalian cell population, when cultured under the organoid formation conditions in the absence of the test molecule, results in an organoid with a disease phenotype; imaging the first organoid following exposure to the test molecule; analyzing one or more images of the first organoid using a neural network that has been trained to assign a probability score of disease or non-disease ranging between 0% and 100%; assigning the first organoid a probability score ranging between 0% and 100%; wherein the test molecule is biologically active against the disease if the probability score of the first organoid is greater than a cutoff probability score of non-disease or lower than a cutoff probability score of disease. |
FILED | Friday, October 04, 2019 |
APPL NO | 17/282039 |
ART UNIT | 2646 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 2503/02 (20130101) C12N 2510/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 33/5014 (20130101) G01N 33/5076 (20130101) Electric Digital Data Processing G06F 18/214 (20230101) G06F 18/217 (20230101) Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2200/04 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30024 (20130101) G06T 2207/30072 (20130101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/764 (20220101) G06V 20/698 (20220101) G06V 2201/03 (20220101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/00 (20190201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141975 | Buckler et al. |
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FUNDED BY |
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APPLICANT(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
INVENTOR(S) | Andrew J. Buckler (Boston, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A. Moulton (Amesbury, Massachusetts); David S. Paik (Boston, Massachusetts) |
ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
FILED | Wednesday, January 17, 2024 |
APPL NO | 18/415137 |
ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
CURRENT CPC | Electric Digital Data Processing G06F 18/24 (20230101) G06F 18/211 (20230101) G06F 18/2148 (20230101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 3/00 (20130101) G06T 5/73 (20240101) G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10048 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10101 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/30096 (20130101) G06T 2207/30104 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/764 (20220101) G06V 20/69 (20220101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142020 | Klein et al. |
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FUNDED BY |
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APPLICANT(S) | Areté Associates (Northridge, California) |
ASSIGNEE(S) | Arete Associates (Northridge, California) |
INVENTOR(S) | Timothy M. Klein (Huntsville, Alabama); Peter J. Rusello (Arlington, Virginia); Benjamin E. K. Sugerman (Baltimore, Maryland); Amanda M. Steck (Huntsville, Alabama) |
ABSTRACT | Systems and methods herein provide for improving visibility in a scene. In one embodiment, a system includes a first camera device operable to capture images of a scene at a first band of wavelengths, and a second camera device operable to capture images of the scene at a second band of wavelengths. The first and second bands are different. The system also includes a processor communicatively coupled to the first and second camera devices, the processor being operable to detect an object in the scene based on a first of the images from the first camera device and based on a first of the images from the second camera device that was captured at substantially a same time as the first image from the first camera device, to estimate an obscurant in the scene based on the first images, and to estimate a visibility parameter of the scene based on the object and the estimated obscurant. |
FILED | Monday, April 25, 2022 |
APPL NO | 17/728906 |
ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 5/92 (20240101) G06T 2207/10048 (20130101) Image or Video Recognition or Understanding G06V 10/26 (20220101) Original (OR) Class G06V 10/82 (20220101) G06V 10/806 (20220101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142177 | Moulton, Jr. et al. |
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FUNDED BY |
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APPLICANT(S) | JRM Enterprises, Inc. (Orlando, Florida) |
ASSIGNEE(S) | JRM Enterprises, Inc. (Orlando, Florida) |
INVENTOR(S) | J. Russ Moulton, Jr. (Orlando, Florida); Steve Butrimas (Orlando, Florida); Christopher Fink (Orlando, Florida); Dan Bybee (Orlando, Florida); Isaac Ehlers (Orlando, Florida); William Hilton (Orlando, Florida) |
ABSTRACT | A dynamic infrared (IR) scene generation system comprising a thin-film screen configured to react to contact by an IR laser; a laser scanning system configured to contact the thin-film screen with laser beam, the laser scanning system comprising a laser scanner, one or more modulators, and an IR laser source; and an image processing system operably connected to a controller configured to control the laser scanning system based on data from the image processing system, wherein the laser scanning system can be configured to contact the thin-film screen with the IR laser based on an IR scene input. |
FILED | Wednesday, August 09, 2023 |
APPL NO | 18/447106 |
ART UNIT | 2881 — Optics |
CURRENT CPC | Weapon Sights; Aiming F41G 3/165 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 2005/0077 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/02 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
US 12139279 | Kraeuter et al. |
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FUNDED BY |
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APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
INVENTOR(S) | Jonathan Kraeuter (Beltsville, Maryland); Matthew Ashmore (Beltsville, Maryland); Michael Cortina (Beltsville, Maryland); Syed-Ali Husain (Beltsville, Maryland); Ross Henry (Greenbelt, Maryland); James Biesinger (Beltsville, Maryland); Edward Cheung (Beltsville, Maryland) |
ABSTRACT | A visual inspection posable invertebrate robot (VIPIR) borescope camera system can inspect components in difficult to reach locations. The system enables dexterous robotic inspection of worksites and areas that were heretofore impossible to inspect via extravehicular activities (EVA) and fixed situational awareness cameras. VIPIR may include: (1) a main drive assembly; (2) a reel system; (3) a video borescope assembly (VBA); (4) an enhanced motorized zoom lens (EMZL); (5) a fixed camera assembly (FCA); (6) a support structure; and/or (7) a main electronics box (MEB). |
FILED | Tuesday, May 19, 2020 |
APPL NO | 16/877713 |
ART UNIT | 2896 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/0005 (20130101) A61B 1/005 (20130101) A61B 1/05 (20130101) A61B 1/008 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 4/00 (20130101) Original (OR) Class Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables B65H 75/4471 (20130101) B65H 75/4486 (20130101) B65H 2403/42 (20130101) Optical Elements, Systems, or Apparatus G02B 23/2484 (20130101) Pictorial Communication, e.g Television H04N 23/54 (20230101) H04N 23/555 (20230101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139708 | Badran et al. |
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FUNDED BY |
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APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Broad Institute, Inc. (Cambridge, Massachusetts) |
ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Borad Institute, Inc. (Cambridge, Massachusetts) |
INVENTOR(S) | Ahmed Hussein Badran (Cambridge, Massachusetts); Erika Alden DeBenedictis (Cambridge, Massachusetts); Kevin Michael Esvelt (Newton, Massachusetts) |
ABSTRACT | The invention, in part, includes compositions comprising quadruplet decoding tRNAs and their encoding sequences. The invention also includes assay methods to assess quadruplet decoding as well as methods of preparing quadruplet decoding suppression tRNAs. |
FILED | Friday, June 05, 2020 |
APPL NO | 16/894359 |
ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/74 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/1058 (20130101) C12N 15/8509 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140551 | Gasiewski et al. |
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FUNDED BY |
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APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado); THE SOIL MOISTURE COMPANY (Boulder, Colorado) |
ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado); THE SOIL MOISTURE COMPANY (Boulder, Colorado) |
INVENTOR(S) | Albin Gasiewski (Boulder, Colorado); Eryan Dai (Boulder, Colorado); Jack Elston (Boulder, Colorado); Maciej Stachura (Boulder, Colorado); Michael Hurowitz (Longmont, Colorado) |
ABSTRACT | A method for determining soil moisture of a scene includes (i) generating a first antenna output in response to an upwelling thermal emission from the scene, (ii) generating a second antenna output in response to a downwelling thermal emission from sky above the scene, (iii) coupling the first antenna output and the second antenna output to yield a combined output having a quadrature phase difference between the first antenna output and the second antenna output, (iv) calculating a brightness-temperature difference based at least partially on the combined output, and (v) calculating a soil moisture based on soil-vegetation radiative transfer model using the brightness-temperature difference. |
FILED | Monday, July 25, 2022 |
APPL NO | 18/291190 |
ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/04 (20130101) Original (OR) Class G01N 33/246 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12140826 | Wu et al. |
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FUNDED BY |
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APPLICANT(S) | California Institute of Technology (Pasadena, California) |
ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
INVENTOR(S) | Yen-Hung Wu (Pasadena, California); Stewart Sherrit (Montrose, California); Valerie Scott Kristof (Pasadena, California); Mina Rais-Zadeh (Pasadena, California); Mustafa B. Coskun (Pasadena, California) |
ABSTRACT | Disclosed herein is a tunable diffraction grating using surface acoustic waves. In some embodiments, the tunable diffraction grating includes a piezoelectric substrate including an interdigital transducer (IDT) region and a delay line region; a plurality of IDT electrodes positioned in the IDT region, wherein the IDT electrodes are each individually addressable such that the voltage applied to each of the electrodes is phase shifted, and wherein the IDT electrodes provide the phase shifted voltage to induce surface acoustic waves in the piezoelectric substrate in a pattern which produce a grating in the delay line region. Advantageously, tunable diffraction gratings have many applications including spectrometers for orbiters and rovers to Mars. |
FILED | Monday, August 09, 2021 |
APPL NO | 17/397767 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/113 (20130101) Original (OR) Class G02F 2201/124 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/25 (20130101) H03H 9/02559 (20130101) H03H 9/02881 (20130101) H03H 9/14502 (20130101) H03H 9/14541 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
US 12138294 | Jaynes et al. |
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FUNDED BY |
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APPLICANT(S) | GENVOR, INC. (Dallas, Texas); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
ASSIGNEE(S) | GENVOR INC. (Chapel Hill, North Carolina); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
INVENTOR(S) | Jesse M. Jaynes (Auburn, Alabama); Kanniah Rajasekaran (Metairie, Louisiana); Jeffrey W. Cary (Covington, Louisiana); Ronald Sayler (Farmington, Arkansas); Rajtilak Majumdar (Metairie, Louisiana) |
ABSTRACT | Aspergillus flavus is an opportunistic, saprophytic fungus that infects maize and other fatty acid-rich food and feed crops and produces toxic and carcinogenic secondary metabolites known as aflatoxins. In vitro studies showed a five-fold increase in antifungal activity of AGM182 (vs. tachyplesin1) against A. flavus. Transgenic maize plants expressing AGM182 under maize Ubiquitin-1 promoter were produced through Agrobacterium-mediated transformation. PCR products confirmed integration of the AGM182 gene, while RT-PCR of maize RNA confirmed the presence of AGM182 transcripts. Maize kernel screening assay using a highly aflatoxigenic A. flavus strain (AF70) showed up to 72% reduction in fungal growth in the transgenic AGM182 seeds compared to isogenic negative control seeds. |
FILED | Monday, July 03, 2023 |
APPL NO | 18/346317 |
ART UNIT | 1662 — Plants |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1767 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8205 (20130101) C12N 15/8216 (20130101) C12N 15/8282 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12139442 | Bakshi et al. |
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FUNDED BY |
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APPLICANT(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
ASSIGNEE(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa) |
INVENTOR(S) | Santanu Bakshi (Ames, Iowa); Robert C. Brown (Ames, Iowa); Ryan G. Smith (Ames, Iowa) |
ABSTRACT | The present application relates to an iron impregnated biochar and its use as a fertilizer. The iron impregnated biochar of the present application has a ratio of iron (III) to iron (II) ranging from 5:1 to 10:1. The biochar may be produced by a method including treating the biomass with an iron (II) ion solution, pyrolyzing the iron (II)-treated biomass in an oxidative environment and recovering the biochar product from the pyrolyzed iron (II)-treated biomass. |
FILED | Tuesday, May 30, 2023 |
APPL NO | 18/325442 |
ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
CURRENT CPC | Inorganic Fertilisers Not Covered by Subclasses C05B, C05C; Fertilisers Producing Carbon Dioxide C05D 9/00 (20130101) Original (OR) Class Mixtures of Fertilisers Covered Individually by Different Subclasses of Class C05; Mixtures of One or More Fertilisers With Materials Not Having a Specific Fertilising Activity, e.g Pesticides, Soil-conditioners, Wetting Agents; Fertilisers Characterised by Their Form C05G 3/80 (20200201) |
VIEW PATENT | @ USPTO: Full Text PDF |
US PP36252 | Milla-Lewis |
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FUNDED BY |
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APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
INVENTOR(S) | Susana Milla-Lewis (Apex, North Carolina) |
ABSTRACT | ‘XZ 14069’ is a medium to dark green perennial zoysiagrass cultivar with medium-fine texture low incidence of large patch disease and aggressive stoloniferous growth producing high density turf performance ideal for low-management landscaping. It is distinguishable from other cultivars by medium-fine texture, plant architecture and characteristics such as high drought tolerance, turf quality, disease resistance and aggressive establishment from minimal input. ‘XZ 14069’ shows persistence under an array of climates including warm-temperate, warm-humid and hot-arid. ‘XZ 14069’ is also genetically distinct from other zoysiagrass cultivars currently in the marketplace known to the Inventor. ‘XZ 14069’ exhibits very low fertility and no inflorescences have been observed. |
FILED | Thursday, July 13, 2023 |
APPL NO | 18/445332 |
ART UNIT | 1661 — Plants |
CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 6/469 (20180501) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
US 12140961 | Dai et al. |
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FUNDED BY |
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APPLICANT(S) | West Virginia University Board of Governors on Behalf of West Virginia University (Morgantown, West Virginia) |
ASSIGNEE(S) | West Virginia University Board of Governors on Behalf of West Virginia University (Morgantown, West Virginia) |
INVENTOR(S) | Fei Dai (Morgantown, West Virginia); Linjun Lu (Morgantown, West Virginia) |
ABSTRACT | Disclosed is a thermal-based automatic roller tracking and mapping system for roller path tracking and mapping in pavement compaction. Accuracy in estimation during roller position tracking and mapping for pavement compaction through the use of thermal imaging is achieved. The tracking and mapping system utilizes an infrared camera for automatic roller path tracking and mapping in pavement construction. The tracking and mapping data associated with the movement of the roller vehicle during compaction of the surface can be generated and visually represented in a user interface accessible to the operator of the roller vehicle. Based on the tracking and mapping data that is generated in real-time and presented to the operator in the user interface, the operator can make adjustments to the roller vehicle and path, as necessary. |
FILED | Monday, November 29, 2021 |
APPL NO | 17/536418 |
ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
CURRENT CPC | Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 1/22 (20220101) B60R 11/04 (20130101) Indexing Scheme Relating to Aspects Cross-cutting Vehicle Technology B60Y 2200/41 (20130101) B60Y 2400/3015 (20130101) Construction Of, or Surfaces For, Roads, Sports Grounds, or the Like; Machines or Auxiliary Tools for Construction or Repair E01C 19/288 (20130101) E01C 19/488 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/02 (20130101) G05D 1/0242 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 5/33 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142163 | Baldwin et al. |
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FUNDED BY |
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APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
INVENTOR(S) | Keith M. Baldwin (McLean, Virginia); Kerry Hutson (McLean, Virginia); Susan M. Schultheis (McLean, Virginia) |
ABSTRACT | The present disclosure generally relates to systems and methods for evaluating radar vectoring aptitude of an individual. An exemplary computer-implemented method comprises: displaying a graphic representation of an aircraft; displaying a predetermined shape of a plurality of predetermined shapes, wherein each of the plurality of predetermined shapes is associated with a facility type; providing an instruction for controlling the aircraft; receiving a plurality of audio inputs from a user; performing a speech-to-text analysis to each of the plurality of audio inputs to obtain a plurality of corresponding text strings; identifying, based on the plurality of corresponding text strings, a plurality of vectoring clearances associated with the aircraft; displaying an animation of the aircraft based on the plurality of vectoring clearances; and based on the plurality of vectoring clearances, calculating a facility-specific aptitude score of the user. |
FILED | Friday, August 16, 2019 |
APPL NO | 16/543267 |
ART UNIT | 3715 — Amusement and Education Devices |
CURRENT CPC | Electric Digital Data Processing G06F 3/147 (20130101) Image Data Processing or Generation, in General G06T 13/80 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 5/06 (20130101) G09B 9/006 (20130101) G09B 9/54 (20130101) Original (OR) Class G09B 19/165 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 5/37 (20130101) G09G 2354/00 (20130101) G09G 2380/12 (20130101) Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/22 (20130101) G10L 15/26 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142253 | Lin et al. |
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FUNDED BY |
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APPLICANT(S) | General Electric Company (Schenectady, New York) |
ASSIGNEE(S) | General Electric Company (Evendale, Ohio) |
INVENTOR(S) | Wendy Wenling Lin (Montgomery, Ohio); David Herman (Beavercreek, Ohio) |
ABSTRACT | A system and method for bonding together a facesheet and an acoustic screen of an acoustic liner using a solid adhesive film having a first adhesive side opposite a second adhesive side are provided. The system includes a solid adhesive film having a first adhesive side opposite a second adhesive side; an acoustic screen bonded to the first adhesive side of the solid adhesive film; and a facesheet bonded to the second adhesive side of the solid adhesive film. The method includes bonding the facesheet to the first adhesive side of the solid adhesive film and bonding the acoustic screen to the second adhesive side of the solid adhesive film. |
FILED | Tuesday, October 05, 2021 |
APPL NO | 17/449980 |
ART UNIT | 2837 — Electrical Circuits and Systems |
CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/12 (20130101) B32B 5/028 (20130101) B32B 7/12 (20130101) B32B 37/1284 (20130101) B32B 38/04 (20130101) B32B 41/00 (20130101) B32B 2038/047 (20130101) B32B 2307/102 (20130101) B32B 2310/0843 (20130101) B32B 2605/18 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/38 (20180101) Jet-propulsion Plants F02K 1/827 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) Sound-producing Devices; Methods or Devices for Protecting Against, or for Damping, Noise or Other Acoustic Waves in General; Acoustics Not Otherwise Provided for G10K 11/168 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
US 12137801 | Tartal et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
INVENTOR(S) | William A. Tartal (Baltimore, Maryland); Joel L. Dewnandan (Bladensburg, Maryland); Joram Shenhar (Fairfax, Virginia) |
ABSTRACT | A portable workstation apparatus includes: a pair of collapsible legs; and a work portion that is attached in a removable manner to the pair of collapsible lags via a pair of brackets. Each leg of the pair of collapsible legs includes: a frame; an extension connected to a first end of the frame; a lower post housed within a sleeve; an upper post; a hinge connecting the lower post and the upper post; a first brace connecting the extension to the sleeve; and a plurality of holes on an exterior face of the lower post or the upper post. Each leg is configured to collapse by folding the upper post towards the lower post via the hinge and rotating the extension toward the lower post. |
FILED | Friday, September 29, 2023 |
APPL NO | 18/478420 |
ART UNIT | 3637 — Static Structures, Supports and Furniture |
CURRENT CPC | Tables; Desks; Office Furniture; Cabinets; Drawers; General Details of Furniture A47B 3/08 (20130101) Original (OR) Class A47B 9/14 (20130101) A47B 21/02 (20130101) A47B 83/04 (20130101) A47B 2003/0824 (20130101) A47B 2009/145 (20130101) A47B 2200/004 (20130101) A47B 2200/0029 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141649 | Simpson |
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FUNDED BY |
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APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
INVENTOR(S) | Ryan J. Simpson (Vienna, Virginia) |
ABSTRACT | The present disclosure relates to a system for reading a barcode independently of image resolution or scale of a captured barcode image. In one embodiment, the system includes an optical sensor and a processor. The optical scanner can scan a barcode, including a plurality of bars and spaces, into a scanned image. The processor can convert the scanned image into binary data. The processor can also calculate numbers of ones (1s) between zeros (0s) in the binary data and determine widths of one of i) each of the bars and ii) each of the spaces based on the calculated numbers of ones (1s). The processor can further calculate numbers of zeros (0s) between ones (1s) in the binary data and determine widths of the other one of i) each of the bars and ii) each of the spaces based on the calculated numbers of zeros (0s). |
FILED | Friday, September 15, 2023 |
APPL NO | 18/468158 |
ART UNIT | 2876 — Optics |
CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) G06K 7/10722 (20130101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12141738 | Jones et al. |
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FUNDED BY |
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APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
INVENTOR(S) | Anthony Cramer Jones (Brooklyn, New York); Dominik Heinrich (New York, New York); Caspar Serge Ouvaroff (New York, New York) |
ABSTRACT | Systems, methods, interface devices, and media for the delivery of physical items using a digital stamp. Various implementations include operations such as receiving a request from a user to deliver an item to a destination using a digital stamp, wherein the item includes destination information and lacks any physical indicator that the delivery fee for the item has been paid or will be paid; receiving a destination address from the user; presenting a delivery fee for the item; and causing the generation of a digital stamp using the destination address and the delivery fee, which may be correlated with the item. |
FILED | Wednesday, April 05, 2023 |
APPL NO | 18/296017 |
ART UNIT | 3628 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0832 (20130101) Original (OR) Class G06Q 20/3223 (20130101) G06Q 50/60 (20240101) Ticket-issuing Apparatus; Fare-registering Apparatus; Franking Apparatus G07B 17/00508 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
US 12138948 | Zlotnick et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Joel Zlotnick (Arlington, Virginia); Jordan Brough (Leesburg, Virginia); Troy Eberhardt (Centreville, Virginia); Tyra McConnell (Knoxville, Maryland); Elizabeth Gil (Bristow, Virginia); Traci Moran (Rockville, Maryland) |
ABSTRACT | A substrate is printed with front side and back side markings. The front side when viewed with reflected light includes: a first marking printed with a first gradient of two colors; a second marking printed with a second gradient of two colors; a first symbol printed with a third gradient of two colors; a second symbol printed with a fourth gradient of two colors; a third symbol printed with a fifth gradient of two colors; and a fourth symbol printed with a sixth gradient of two colors. The back side when viewed with reflected light includes: a third marking printed with the fourth gradient; a fourth marking printed with the third gradient; a fifth symbol printed with the second gradient; a sixth symbol printed with the first gradient; a seventh symbol printed with the sixth gradient; and an eighth symbol printed with the fifth gradient. |
FILED | Wednesday, December 20, 2023 |
APPL NO | 18/389913 |
ART UNIT | 3637 — Static Structures, Supports and Furniture |
CURRENT CPC | Printing Machines or Presses B41F 1/16 (20130101) B41F 7/025 (20130101) B41F 31/008 (20130101) B41F 33/0036 (20130101) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 1/10 (20130101) B41M 1/14 (20130101) B41M 3/14 (20130101) B41M 3/148 (20130101) B41M 2205/34 (20130101) Indexing Scheme Relating to Printing, Lining Machines, Typewriters, and to Stamps B41P 2227/10 (20130101) Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/29 (20141001) Original (OR) Class B42D 25/333 (20141001) B42D 25/342 (20141001) B42D 25/351 (20141001) B42D 25/378 (20141001) B42D 25/405 (20141001) |
VIEW PATENT | @ USPTO: Full Text PDF |
US 12142098 | Vemury et al. |
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FUNDED BY |
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APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
INVENTOR(S) | Arun R. Vemury (North Bethesda, Maryland); Yevgeniy B. Sirotin (Severna Park, Maryland); Cynthia M. Cook (Pittsburg, Pennsylvania); John J. Howard (Bethesda, Maryland); Jerry L. Tipton (Severn, Maryland) |
ABSTRACT | In examples, a relative skin reflectance of a captured image of a subject is quantified. Based on the relative skin reflectance, the captured image is determined as suitable or not suitable for biometric identification. When the captured image is determined not suitable, a remedial capture setting is calculated and provided to an image capturing resource. Another captured image of the subject, captured under the remedial capture setting, is received from the image capturing resource. The relative skin reflectance of the another captured image is quantified and based thereon, there is a determining of whether the another captured image is suitable or is not suitable. |
FILED | Thursday, January 11, 2024 |
APPL NO | 18/410616 |
ART UNIT | 2488 — Recording and Compression |
CURRENT CPC | Image or Video Recognition or Understanding G06V 10/141 (20220101) G06V 40/161 (20220101) G06V 40/162 (20220101) G06V 40/166 (20220101) G06V 40/168 (20220101) G06V 40/172 (20220101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 9/00563 (20130101) Original (OR) Class Pictorial Communication, e.g Television H04N 23/71 (20230101) H04N 23/74 (20230101) H04N 23/76 (20230101) H04N 23/611 (20230101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
US 12142020 | Klein et al. |
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FUNDED BY |
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APPLICANT(S) | Areté Associates (Northridge, California) |
ASSIGNEE(S) | Arete Associates (Northridge, California) |
INVENTOR(S) | Timothy M. Klein (Huntsville, Alabama); Peter J. Rusello (Arlington, Virginia); Benjamin E. K. Sugerman (Baltimore, Maryland); Amanda M. Steck (Huntsville, Alabama) |
ABSTRACT | Systems and methods herein provide for improving visibility in a scene. In one embodiment, a system includes a first camera device operable to capture images of a scene at a first band of wavelengths, and a second camera device operable to capture images of the scene at a second band of wavelengths. The first and second bands are different. The system also includes a processor communicatively coupled to the first and second camera devices, the processor being operable to detect an object in the scene based on a first of the images from the first camera device and based on a first of the images from the second camera device that was captured at substantially a same time as the first image from the first camera device, to estimate an obscurant in the scene based on the first images, and to estimate a visibility parameter of the scene based on the object and the estimated obscurant. |
FILED | Monday, April 25, 2022 |
APPL NO | 17/728906 |
ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
CURRENT CPC | Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 5/92 (20240101) G06T 2207/10048 (20130101) Image or Video Recognition or Understanding G06V 10/26 (20220101) Original (OR) Class G06V 10/82 (20220101) G06V 10/806 (20220101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
US 12138366 | Zlotnick et al. |
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FUNDED BY |
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APPLICANT(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
ASSIGNEE(S) | The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia); The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
INVENTOR(S) | Hannah M. Zlotnick (Philadelphia, Pennsylvania); Andrew Todd Clark (North Wales, Pennsylvania); Robert L. Mauck (Philadelphia, Pennsylvania); Xuemei Cheng (Bryn Mawr, Pennsylvania) |
ABSTRACT | The present disclosure is concerned with magneto-patterned cell-laden hydrogel materials and methods of making and using those materials. The disclosed materials are useful for, among other things, repair of tissue defects, e.g., tissue at a tissue interface such as a bone-cartilage interface. |
FILED | Tuesday, April 13, 2021 |
APPL NO | 17/229829 |
ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/042 (20130101) A61L 27/045 (20130101) A61L 27/46 (20130101) A61L 27/047 (20130101) A61L 27/52 (20130101) A61L 27/222 (20130101) A61L 27/225 (20130101) A61L 27/3847 (20130101) Original (OR) Class A61L 27/3852 (20130101) A61L 2300/41 (20130101) A61L 2300/43 (20130101) A61L 2300/258 (20130101) A61L 2300/402 (20130101) A61L 2300/406 (20130101) A61L 2300/408 (20130101) A61L 2300/414 (20130101) A61L 2300/426 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
US 12139723 | Stice et al. |
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FUNDED BY |
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APPLICANT(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia); Aruna Bio, Inc. (Athens, Georgia) |
ASSIGNEE(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia); ARUNA BIO, INC. (Athens, Georgia) |
INVENTOR(S) | Steven L. Stice (Athens, Georgia); Robin Lynn Webb (Winterville, Georgia); Tracey A. Stice (Athens, Georgia) |
ABSTRACT | Disclosed herein are neural extracellular vesicles (EVs) and methods of using these EVs in the treatment of spinal cord injury, stroke, and traumatic brain injury and neurodegenerative disease. |
FILED | Friday, April 23, 2021 |
APPL NO | 17/238760 |
ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5068 (20130101) A61K 9/5176 (20130101) A61K 35/12 (20130101) A61K 35/30 (20130101) A61K 35/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) Original (OR) Class C12N 5/0622 (20130101) C12N 5/0623 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) C12N 2533/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) |
VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
US 12141657 | Figgatt et al. |
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FUNDED BY |
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APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); IonQ, Inc. (College Park, Maryland) |
ASSIGNEE(S) | IonQ, Inc. (College Park, Maryland); University of Maryland, College Park (College Park, Maryland) |
INVENTOR(S) | Caroline Figgatt (Denver, Colorado); Aaron Ostrander (Woodstock, Georgia); Norbert M. Linke (Stevenson, Maryland); Kevin A. Landsman (Rockville, Maryland); Daiwei Zhu (College Park, Maryland); Dmitri Maslov (Falls Church, Virginia); Christopher Monroe (Columbia, Maryland) |
ABSTRACT | The disclosure describes various aspects related to enabling effective multi-qubit operations, and more specifically, to techniques for enabling parallel multi-qubit operations on a universal ion trap quantum computer. In an aspect, a method of performing quantum operations in an ion trap quantum computer or trapped-ion quantum system includes implementing at least two parallel gates of a quantum circuit, each of the at least two parallel gates is a multi-qubit gate, each of the at least two parallel gates is implemented using a different set of ions of a plurality of ions in a ion trap, and the plurality of ions includes four or more ions. The method further includes simultaneously performing operations on the at least two parallel gates as part of the quantum operations. A trapped-ion quantum system and a computer-readable storage medium corresponding to the method described above are also disclosed. |
FILED | Friday, April 28, 2023 |
APPL NO | 18/309486 |
ART UNIT | 2182 — Computer Architecture and I/O |
CURRENT CPC | Electric Digital Data Processing G06F 7/501 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
VIEW PATENT | @ USPTO: Full Text PDF |
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How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 12, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
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APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
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The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
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