FedInvent™ Patents
Patent Details for Tuesday, November 19, 2024
This page was updated on Tuesday, November 19, 2024 at 06:26 PM GMT
Department of Health and Human Services (HHS)
| US 12144344 | Benfey et al. |
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| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Philip Benfey (Durham, North Carolina); Alexandra Dickinson (Durham, North Carolina) |
| ABSTRACT | This disclosure relates to methods of regulating growth in a plant. Specifically, the methods of the disclosure regulate growth of the plant by administration of a composition comprising an effective amount of one or more apocarotenoids to the plant, its part, or the seed. |
| FILED | Saturday, November 09, 2019 |
| APPL NO | 17/291992 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 31/02 (20130101) A01N 31/04 (20130101) A01N 33/02 (20130101) Original (OR) Class A01N 37/06 (20130101) A01N 37/08 (20130101) A01N 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144491 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Zhiwen Liu (State College, Pennsylvania); Jian Yang (State College, Pennsylvania); Yizhu Chen (Fremont, California); Dingbowen Wang (State College, Pennsylvania) |
| ABSTRACT | A spectrally encoded fluorescence imaging system includes a multi-wavelength excitation light source emitting excitation light for illuminating a sample, optical components for introducing spectral encoding to focus different wavelengths of the excitation light at different positions in the sample to generate fluorescence at different, spatial positions, and band-shifting florescence imaging probes exhibiting excitation-dependent emission band, causing the fluorescence generated at different spatial positions to exhibit different band shifts, such that image information is encoded in the band-shifted fluorescence spectrums for parallel detection by a spectrometer or arrayed detectors operable to resolve different wavelengths. |
| FILED | Tuesday, July 30, 2019 |
| APPL NO | 17/264161 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/043 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 49/006 (20130101) A61K 49/0021 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6458 (20130101) G01N 2021/6419 (20130101) G01N 2021/6421 (20130101) G01N 2021/6423 (20130101) G01N 2021/6439 (20130101) G01N 2021/8893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144587 | Godavarty et al. |
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| FUNDED BY |
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| APPLICANT(S) | Anuradha Godavarty (Miami, Florida); Kevin Leiva (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Anuradha Godavarty (Miami, Florida); Kevin Leiva (Miami, Florida) |
| ABSTRACT | Systems and methods for imaging breath-hold (BH)-induced oxygenation changes in a patient are provided. A non-invasive, non-contact device can be used to image BH-induced oxygenation changes in one or more parts (e.g., foot) of a patient. The patient can hold his or her breath for a set amount of time while imaging is performed using the device, and the imaging can be performed before and/or after the time while the patient is holding his or her breath as well (e.g., during a recovery period). This enables tissue oxygenation based flow correlation independent of melanin concentration (e.g., skin color) of the patient and/or the curvature of the tissue (of the patient) being imaged. |
| FILED | Friday, January 19, 2024 |
| APPL NO | 18/417405 |
| ART UNIT | 3797 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/083 (20130101) A61B 5/0086 (20130101) Original (OR) Class A61B 5/445 (20130101) A61B 5/742 (20130101) A61B 2576/00 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/20208 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144620 | Scherer et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Axel Scherer (Barnard, Vermont); Meisam Honarvar Nazari (Pasadena, California); Muhammad Mujeeb-U-Rahman (San Gabriel, California); Mehmet Sencan (Pasadena, California); Arti Gaur (Hanover, New Hampshire) |
| ABSTRACT | A fully integrated small size implantable sensing device is described, which can include a sensor and an electronic circuit to interface with the sensor and communicate with an external device. Various fabrication methods for the sensing device are described, including provision of wells, created using same fabrication technology as the electronic circuit, to contain electrodes of the sensor and corresponding functionalization chemicals. Such implantable sensing device can be used for a variety of electrochemical measuring applications within a living body as well as actuation by injecting a current into the living body. |
| FILED | Wednesday, September 29, 2021 |
| APPL NO | 17/489610 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0031 (20130101) A61B 5/076 (20130101) A61B 5/1451 (20130101) A61B 5/1459 (20130101) A61B 5/1473 (20130101) Original (OR) Class A61B 5/4839 (20130101) A61B 5/14532 (20130101) A61B 5/14546 (20130101) A61B 5/14735 (20130101) A61B 5/14865 (20130101) A61B 17/3468 (20130101) A61B 2560/0219 (20130101) A61B 2562/04 (20130101) A61B 2562/028 (20130101) A61B 2562/125 (20130101) A61B 2562/0209 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/172 (20130101) A61M 5/1723 (20130101) A61M 5/14276 (20130101) A61M 2205/3523 (20130101) A61M 2205/8237 (20130101) A61M 2207/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144642 | Barton et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Jennifer Barton (Tucson, Arizona); Urs Utzinger (Tucson, Arizona); Tyler Tate (Tucson, Arizona); Maureen Keenan (Tucson, Arizona); John Forbes Black (Bainbridge Island, Washington) |
| ABSTRACT | A falloposcope is described, and a method of screening a patient for fallopian tube and/or ovarian cancer with the falloposcope. The falloposcope can perform optical imaging, including fluorescence imaging and/or optical coherence tomography (OCT), and optionally include a channel for a sampling wire, within a diameter of about 0.7 millimeter. The method includes inserting the falloposcope through a lumen of vagina, cervix, uterus, and fallopian tube so a tip of the falloposcope is in proximity to a first fallopian tube or ovary of the patient; providing fluorescence stimulus wavelength through an illumination fiber of the falloposcope while imaging light at fluorescence emission wavelength through a coherent fiber bundle to form fluorescence emissions images; and determining suspect tissue. Then the sampling wire is used to collect cells from the suspect tissue for karyotype and other analysis. |
| FILED | Monday, March 08, 2021 |
| APPL NO | 17/195221 |
| ART UNIT | 3798 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/05 (20130101) A61B 1/07 (20130101) A61B 1/0057 (20130101) A61B 1/063 (20130101) A61B 1/0125 (20130101) A61B 1/303 (20130101) A61B 5/0066 (20130101) A61B 5/0084 (20130101) A61B 5/4325 (20130101) Original (OR) Class A61B 10/04 (20130101) A61B 10/0291 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144667 | Tichauer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Kenneth M. Tichauer (Chicago, Illinois); Scott C. Davis (Woodville, New Hampshire); Brian William Pogue (Hanover, New Hampshire) |
| ABSTRACT | An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to process the first and second medical images by fitting parameters of a pharmacokinetic model to the first medical images, identifying a nontargeted tissue type, scaling the fitted parameters to best match the nontargeted tissue in the second medical images, executing the pharmacokinetic model to prepare a correction image, and generating corrected medical images by subtracting the correction image from the second medical images. |
| FILED | Monday, November 13, 2023 |
| APPL NO | 18/389128 |
| ART UNIT | 3797 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/481 (20130101) Original (OR) Class A61B 6/4417 (20130101) A61B 6/5235 (20130101) A61B 6/5247 (20130101) Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/20224 (20130101) G06T 2207/30024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144716 | MacEwan et al. |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Matthew R. MacEwan (St. Louis, Missouri); Jingwei Xie (St. Louis, Missouri); Zack Ray (St. Louis, Missouri); Younan Xia (St. Louis, Missouri) |
| ABSTRACT | A multi-laminar electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers, and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is combined with the first layer. A first portion of the scaffold includes a higher density of fibers than a second portion of the scaffold, and the first portion has a higher tensile strength than the second portion. The scaffold is configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The scaffold is configured to be applied to the tissue substrate containing the defect, and is sufficiently flexible to facilitate application of the scaffold to uneven surfaces of the tissue substrate, and to enable movement of the scaffold by the tissue substrate. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/358463 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/02 (20130101) Original (OR) Class A61F 2/0063 (20130101) A61F 2/105 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/22 (20130101) A61L 15/42 (20130101) A61L 27/14 (20130101) A61L 27/50 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/05 (20190201) B29C 48/142 (20190201) Apparatus for Enzymology or Microbiology; C12M 25/14 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0076 (20130101) D01D 5/0092 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/728 (20130101) D04H 3/016 (20130101) D04H 3/073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144772 | Gregg et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Robert D. Gregg (Allen, Texas); Ge Lv (Dallas, Texas) |
| ABSTRACT | Total energy shaping control methods and devices for powered orthosis for controlling the device to counteract forces exerted on the person including inertial forces. |
| FILED | Monday, May 21, 2018 |
| APPL NO | 16/615495 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/11 (20130101) A61B 5/0057 (20130101) A61B 5/112 (20130101) A61B 5/6812 (20130101) A61B 5/6828 (20130101) A61B 5/6829 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/0102 (20130101) A61F 2005/0155 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/024 (20130101) A61H 1/0244 (20130101) A61H 1/0262 (20130101) Original (OR) Class A61H 1/0266 (20130101) A61H 3/00 (20130101) A61H 2201/1207 (20130101) A61H 2201/1472 (20130101) A61H 2201/5061 (20130101) A61H 2201/5064 (20130101) A61H 2201/5069 (20130101) A61H 2201/5084 (20130101) A61H 2205/10 (20130101) A61H 2205/12 (20130101) A61H 2230/625 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) B25J 9/126 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144788 | Palczewski et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Krzysztof Palczewski (Bay Village, Ohio); Philip Kiser (Cleveland, Ohio); Jianye Zhang (Cleveland, Ohio); Mohsen Badiee (Shaker Heights, Ohio); Gregory Tochtrop (Shaker Heights, Ohio) |
| ABSTRACT | A method of treating an ocular disorder in a subject in need thereof includes administering to the subject a therapeutically effective amount of a retinal sequestering compound of formula (I). |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 17/677524 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/137 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144791 | Deng |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Xingming Deng (Atlanta, Georgia) |
| ABSTRACT | In certain embodiments, this disclosure relates to KRAS agonists, pharmaceutical composition, and uses in managing cancer. In certain embodiments, the KRAS agonist is 4-(4-(2-bromoacetamido)butyl)benzoic acid, salt, prodrug, or derivative thereof. In certain embodiments, this disclosure relates to methods of treating cancer comprising administering an effective amount of a compound of Formula I, salt, prodrug, or derivative thereof, to a subject in need thereof, wherein, substituents are reported herein. |
| FILED | Tuesday, April 04, 2023 |
| APPL NO | 18/295674 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/195 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144805 | Mehrara et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Babak Mehrara (Chappaqua, New York); Jason Gardenier (Altona, New York); Ira Savetsky (Cedarhurst, New York); Omer Aras (New York, New York) |
| ABSTRACT | Provided are pharmaceutical compositions and methods of treating or preventing edema, using an anti-T cell agent, an anti-TGF-β1 agent, or an anti-angiotensin agent, preferably a combination of at least two such agents. The pharmaceutical compositions can be formulated for systemic or local administration, and are preferably administered topically. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/102437 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0014 (20130101) A61K 31/42 (20130101) A61K 31/277 (20130101) A61K 31/277 (20130101) A61K 31/401 (20130101) A61K 31/401 (20130101) A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 31/4412 (20130101) Original (OR) Class A61K 31/4418 (20130101) A61K 31/4418 (20130101) A61K 38/13 (20130101) A61K 38/13 (20130101) A61K 45/06 (20130101) A61K 47/10 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144816 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Taekyu Lee (Brentwood, Tennessee); James C. Tarr (Franklin, Tennessee); KyuOk Jeon (Nashville, Tennessee); James M. Salovich (Nashville, Tennessee); Subrata Shaw (Nashville, Tennessee); Nagarathanam Veerasamy (Nashville, Tennessee); Kwangho Kim (Nashville, Tennessee); Plamen P. Christov (Mount Juliet, Tennessee); Edward T. Olejniczak (Nashville, Tennessee); Bin Zhao (Brentwood, Tennessee); Stephen W. Fesik (Nashville, Tennessee); Zhiguo Bian (Lake Bluff, Illinois) |
| ABSTRACT | The present disclosure provides for compounds that inhibit the activity of an anti-apoptotic Bcl-2 family member Myeloid cell leukemia-1 (Mcl-1) protein. The present disclosure also provides for pharmaceutical compositions as well as methods for using compounds for treatment of diseases and conditions (e.g., cancer) characterized by the over-expression or dysregulation of Mcl-1 protein. |
| FILED | Friday, December 09, 2022 |
| APPL NO | 18/064206 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/538 (20130101) A61K 31/551 (20130101) Original (OR) Class A61K 31/4985 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 401/14 (20130101) C07D 403/04 (20130101) C07D 403/14 (20130101) C07D 487/04 (20130101) C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144826 | Lim et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Wendell A. Lim (San Francisco, California); Hideho Okada (San Francisco, California); Kole T. Roybal (San Francisco, California); Joseph H. Choe (San Francisco, California); Payal B. Watchmaker (San Francisco, California) |
| ABSTRACT | Methods are provided for treating a subject for an EGFRvIII expressing glioblastoma. The methods of the present disclosure involve administering to the subject a molecular circuit that is primed by EGFRvIII to induce one or more encoded therapeutics specific for one or more antigens expressed by the glioblastoma. Nucleic acids containing sequences encoding all or portions of such circuits are also provided, as well as cells, expression cassettes and vectors that contain such nucleic acids. Also provided are kits for practicing the described methods. |
| FILED | Thursday, April 04, 2019 |
| APPL NO | 17/042030 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/71 (20130101) C07K 14/7051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144828 | Georgiou et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | George Georgiou (Austin, Texas); Everett Stone (Austin, Texas); John Blazeck (Austin, Texas); Christos Karamitros (Austin, Texas) |
| ABSTRACT | Methods and compositions related to the use of a protein with kynureninase activity are described. For example, in certain aspects there may be disclosed a modified kynureninase capable of degrading kynurenine. Furthermore, certain aspects of the invention provide compositions and methods for the treatment of cancer with kynurenine depletion using the disclosed proteins or nucleic acids. |
| FILED | Thursday, April 06, 2023 |
| APPL NO | 18/296687 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/46 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 16/2818 (20130101) C07K 16/2827 (20130101) Enzymes C12Y 307/01003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144853 | Murphy et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Sean C. Murphy (Seattle, Washington); Bradley C. Stone (Seattle, Washington) |
| ABSTRACT | In one aspect, the present disclosure provides a trapping vaccine composition comprising a trapping antigenic component, a protective component, and a liver cell-targeting component, wherein the trapping antigenic component comprises a nucleic acid molecule or a protein, the protective component comprises a synthetic or non-natural molecule or formation of synthetic or non-natural molecules, and wherein the liver cell-targeting component is capable of delivering the vaccine composition to a liver cell or liver tissue. The present disclosure additional provides vaccination methods comprising (i) administering a priming composition comprising a priming antigenic component or a first dose comprising the priming composition to the mammal; and (ii) administering a trapping composition comprising a trapping antigenic component, a protective component, and a liver cell-targeting component, or a second dose comprising the second composition to the mammal, wherein the priming and trapping compositions or doses are not administered concurrently and wherein the number of resident memory T cells in the liver are increased following administration of the trapping composition. In certain embodiments, vaccine compositions and regimes are provided that protect against liver-tropic pathogens, e.g., a malarial infection. In an embodiment, a vaccine composition and regimen are provided that protect against an infection caused by P. falciparum or P. yoelli sporozoites. |
| FILED | Tuesday, January 12, 2021 |
| APPL NO | 17/147438 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/015 (20130101) Original (OR) Class A61K 2039/52 (20130101) A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) Peptides C07K 14/445 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144857 | Kawaoka et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Gabriele Neumann (Madison, Wisconsin); Huihui Kong (Madison, Wisconsin) |
| ABSTRACT | Methods of preparing influenza viruses having altered immunodominant epitopes in HA, e.g., having one or more residues in one or more of antigenic sites A-E in HA altered, and viral vectors, e.g., influenza virus VLPs or non-influenza viruses or VLPs thereof expressing or having influenza HAs with altered immunogenicity as a result of altered immunodominant epitopes therein are provided. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/813178 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 2039/521 (20130101) A61K 2039/5258 (20130101) Peptides C07K 16/34 (20130101) C07K 16/1018 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144897 | Nair et al. |
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| FUNDED BY |
|
| APPLICANT(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Madhavan Nair (Coral Gables, Florida); Andrea Raymond (Miramar, Florida); Arti Vashist (Miami, Florida) |
| ABSTRACT | A method of treatment or prevention of HIV and other viral infection comprising the administration of a biopolymer-based hydrogel nanoparticles and/or microparticles. In preferred embodiments, the particles comprise chitosan, hydroxyethyl cellulose (HEC), and linseed oil polyol. These biopolymer-based hydrogel nanoparticles and/or microparticles are antiviral agents that can be employed alone or in combination with other drugs for treatment of the viral infection. Further, the pre-treatment with the particles is highly effective at inhibiting viruses. Therefore, this antiviral biopolymer-based hydrogel nanoparticles and/or microparticles may also be employed as a prophylactic. |
| FILED | Friday, June 05, 2020 |
| APPL NO | 17/615940 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 9/2081 (20130101) A61K 9/5146 (20130101) A61K 9/5161 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145922 | Sibley et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The University of Kansas (Lawrence, Kansas); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The University of Kansas (Lawrence, Kansas); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | David R. Sibley (Bethesda, Maryland); Amy Elizabeth Moritz (Bethesda, Maryland); R. Benjamin Free (Bethesda, Maryland); Joseph P. Steiner (Bethesda, Maryland); Noel Terrence Southall (Rockville, Maryland); Marc Ferrer (Rockville, Maryland); Xin Hu (Rockville, Maryland); Warren S. Weiner (Boston, Massachusetts); Jeffrey Aubé (Chapel Hill, North Carolina); Kevin Frankowski (Chapel Hill, North Carolina) |
| ABSTRACT | The disclosure of a compound of Formula I or a pharmaceutically acceptable salt thereof The variables W, R1, R2, R3, and R4 are defined in the disclosure. The disclosure provides a compound or salt of Formula I together with a pharmaceutically acceptable carrier. The disclosure also provides methods of treating a patient for Parkinson's disease and related syndromes, dyskinesia, especially dyskinesias secondary to treating Parkinson's disease with L-DOPA, neurodegenerative disorders such as Alzheimer's disease and dementia, Huntington's disease, restless legs syndrome, bipolar disorder and depression, schizophrenia, cognitive dysfunction, or substance use disorders, the methods comprising administering a compound of Formula I or salt thereof to the patient. The disclosure provides combination methods of treatment in which the compound of Formula I is administered to the patient together with one or more additional active agents. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/111241 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Heterocyclic Compounds C07D 209/42 (20130101) C07D 213/65 (20130101) C07D 213/81 (20130101) C07D 235/24 (20130101) C07D 295/185 (20130101) C07D 307/85 (20130101) C07D 317/64 (20130101) C07D 333/70 (20130101) C07D 401/12 (20130101) Original (OR) Class C07D 405/12 (20130101) C07D 409/12 (20130101) C07D 471/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145962 | Felsenstein et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Kenneth Felsenstein (Denver, Colorado); Dan Theodorescu (Englewood, Colorado); Ryan T. Gill (Denver, Colorado) |
| ABSTRACT | Provided herein, in some embodiments, are methods and compositions for gene editing using a trackable gene library, for example, a barcoded and gene edited library. |
| FILED | Monday, February 04, 2019 |
| APPL NO | 16/966339 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/64 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/08 (20130101) C40B 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145964 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Christopher J. Chang (Berkeley, California); Shang Jia (Berkeley, California) |
| ABSTRACT | Proteins are labeled by contacting the protein with a thiophosphorodichloridate reagent under conditions to effect chemoselective histidine conjugation. |
| FILED | Saturday, March 20, 2021 |
| APPL NO | 17/207609 |
| ART UNIT | 1678 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 1/13 (20130101) Original (OR) Class C07K 1/113 (20130101) C07K 14/00 (20130101) C07K 2319/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145966 | Matoba |
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| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| INVENTOR(S) | Nobuyuki Matoba (Owensboro, Kentucky) |
| ABSTRACT | Polypeptides are provided that include an actinohivin variant polypeptide. The actinohivin variant polypeptide can be operably connected to an antibody fragment, such as a fragment crystallizable (Fc) region of immunoglobulin (Ig) G. Nucleic acid sequences, expression vectors, and transformed plant cells useful for producing the polypeptides are also provided. Further provided are methods for treating a viral infection or a cancer in a subject and include the step of administering the actinohivin variant polypeptide to the subject. |
| FILED | Friday, February 09, 2018 |
| APPL NO | 16/485021 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 11/00 (20180101) A61P 31/18 (20180101) A61P 35/00 (20180101) A61P 35/04 (20180101) Peptides C07K 14/36 (20130101) Original (OR) Class C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8258 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145968 | Kwong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Peter Kwong (Washington, District of Columbia); Marie Pancera (Seattle, Washington); Tongqing Zhou (Boyds, Maryland); Ivelin Georgiev (Nashville, Tennessee); Michael Gordon Joyce (Washington, District of Columbia); Priyamvada Acharya (Chapel Hill, North Carolina); Jason Gorman (Washington, District of Columbia); Yongping Yang (Potomac, Maryland); Guillaume Stewart-Jones (Cambridge, Massachusetts); Rita Chen (St. Louis, Missouri); Gwo-Yu Chuang (Rockville, Maryland); John Mascola (Rockville, Maryland); Baoshan Zhang (Bethesda, Maryland); Cheng Cheng (Bethesda, Maryland); Mallika Sastry (Rockville, Maryland); Aliaksandr Druz (Germantown, Maryland) |
| ABSTRACT | HIV-1 Env ectodomain trimers stabilized in a prefusion mature closed conformation and methods of their use and production are disclosed. In several embodiments, the HIV-1 Env ectodomain trimers and/or nucleic acid molecules can be used to generate an immune response to HIV-1 in a subject. In additional embodiments, the therapeutically effective amount of the HIV-1 Env ectodomain trimers can be administered to a subject in a method of treating or preventing HIV-1 infection. |
| FILED | Monday, October 03, 2022 |
| APPL NO | 17/937719 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 2039/55555 (20130101) A61K 2039/55561 (20130101) A61K 2039/55577 (20130101) Peptides C07K 14/005 (20130101) C07K 14/435 (20130101) Original (OR) Class C07K 16/1063 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16022 (20130101) C12N 2740/16034 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56988 (20130101) G01N 2333/162 (20130101) G01N 2469/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145991 | Westlund High et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNM Rainforest Innovations (Albuquerque, New Mexico); LOYOLA UNIVERSITY OF CHICAGO (Maywood, Illinois) |
| ASSIGNEE(S) | UNM Rainforest Innovations (Albuquerque, New Mexico); Loyola University of Chicago (Maywood, Illinois) |
| INVENTOR(S) | Karin Westlund High (Albuquerque, New Mexico); Ravi Venkata Durvasula (Albuquerque, New Mexico); Adinarayana Kunamneni (Albuquerque, New Mexico) |
| ABSTRACT | A pharmaceutical composition generally includes a therapeutic antibody, or fragment thereof, and a pharmaceutically acceptable carrier. The therapeutic antibody specifically binds to a target peptide that mediates pain in a subject. The composition may be administered to a subject experiencing pain to at least partially alleviate the pain. |
| FILED | Friday, November 01, 2019 |
| APPL NO | 17/284208 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/02 (20180101) A61P 29/02 (20180101) Peptides C07K 16/2869 (20130101) Original (OR) Class C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146136 | Khvorova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Loïc Maurice René Jean Roux (Worcester, Massachusetts); Ken Yamada (Boston, Massachusetts) |
| ABSTRACT | This disclosure relates to the synthesis of novel modified oligonucleotides. The synthesis of novel phosphoramidites are also provided. |
| FILED | Friday, March 26, 2021 |
| APPL NO | 17/213852 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/067 (20130101) C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/314 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146137 | Marbán et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Eduardo Marbán (Los Angeles, California); Linda Cambier (Los Angeles, California); Geoffrey De Couto (Los Angeles, California) |
| ABSTRACT | Some embodiments of the methods and compositions provided herein relate to treating a subject suffering from hypertension, a cardiac injury, or a metabolic disorder. Some embodiments include administering an exosome to a subject. Some embodiments include administering an oligonucleotide to the subject. In some embodiments, the oligonucleotide comprises a Y-RNA or Y-RNA fragment such as EV-YF1 or EV-YF1-U16. In some embodiments, the oligonucleotide or exosome also has a therapeutic effect on the subject. |
| FILED | Wednesday, January 30, 2019 |
| APPL NO | 16/966840 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) A61K 47/6911 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) A61P 13/12 (20180101) A61P 37/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1136 (20130101) Original (OR) Class C12N 2310/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146151 | Asokan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Aravind Asokan (Durham, North Carolina); Trevor Gonzalez (Durham, North Carolina); Lawrence Patrick Havlik (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides adeno-associated virus (AAV) vectors, comprising coevolved capsid variant proteins, pharmaceutical compositions, methods of making, and methods for delivering such to a subject. |
| FILED | Tuesday, September 26, 2023 |
| APPL NO | 18/474506 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146152 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy Lu (Cambridge, Massachusetts); Shota Nakade (Cambridge, Massachusetts) |
| ABSTRACT | The disclosure provides systems, methods, and compositions for a target specific nuclease and a blunting enzyme to correct frameshift mutations for genome editing and treatment of diseases. In some embodiments, the target specific nuclease and the blunting enzyme are combined with a guide RNA and/or a microhomology-mediated end joining (MMEJ) inhibitor. |
| FILED | Tuesday, November 15, 2022 |
| APPL NO | 18/055718 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146156 | Gabrilovich |
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| FUNDED BY |
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| APPLICANT(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Wistar Institute of Anatomy and Biology (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Dmitry I. Gabrilovich (Villanova, Pennsylvania) |
| ABSTRACT | Provided herein are methods of generating MDSCs ex vivo. The methods include culturing blood cells with an LRP2 agonist. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 17/623978 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/14 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0634 (20130101) Original (OR) Class C12N 2500/24 (20130101) C12N 2501/22 (20130101) C12N 2501/385 (20130101) C12N 2501/2306 (20130101) C12N 2506/1353 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146158 | Sentman |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Charles L. Sentman (Grantham, New Hampshire) |
| ABSTRACT | The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed to express a functional non-TCR receptor. The invention also pertains to methods of making said TCR-deficient T cells, and methods of reducing or ameliorating, or preventing or treating, diseases and disorders using said TCR-deficient T cells, populations thereof, or compositions comprising the same. |
| FILED | Monday, October 23, 2023 |
| APPL NO | 18/492221 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4611 (20230501) A61K 39/4632 (20230501) A61K 39/464429 (20230501) A61K 2035/124 (20130101) A61K 2039/585 (20130101) A61K 2239/31 (20230501) A61K 2239/38 (20230501) A61K 2239/48 (20230501) A61K 2239/59 (20230501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2501/515 (20130101) C12N 2510/02 (20130101) C12N 2511/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146162 | Daley |
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| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (, None) |
| INVENTOR(S) | George Q. Daley (Cambridge, Massachusetts) |
| ABSTRACT | Embodiments herein relate to in vitro production methods of hematopoietic stem cell (HSC) and hematopoietic stem and progenitor cell (HSPC) that have long-term multilineage hematopoiesis potentials upon in vivo engraftment. The HSC and HSPCs are derived from pluripotent stem cells-derived hemogenic endothelia cells (HE) by non-integrative episomal vectors-based gene transfer. |
| FILED | Wednesday, December 28, 2022 |
| APPL NO | 18/147554 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) Original (OR) Class C12N 2500/24 (20130101) C12N 2500/38 (20130101) C12N 2500/44 (20130101) C12N 2501/14 (20130101) C12N 2501/15 (20130101) C12N 2501/26 (20130101) C12N 2501/32 (20130101) C12N 2501/41 (20130101) C12N 2501/105 (20130101) C12N 2501/115 (20130101) C12N 2501/125 (20130101) C12N 2501/145 (20130101) C12N 2501/165 (20130101) C12N 2501/602 (20130101) C12N 2501/603 (20130101) C12N 2501/604 (20130101) C12N 2501/605 (20130101) C12N 2501/606 (20130101) C12N 2501/608 (20130101) C12N 2501/2303 (20130101) C12N 2501/2306 (20130101) C12N 2501/2311 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146165 | Zon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (, None) |
| INVENTOR(S) | Leonard I. Zon (Brookline, Massachusetts); Elliott J. Hagedorn (Jamaica Plain, Massachusetts) |
| ABSTRACT | The technology described herein relates to compositions and methods of generating endothelial niche cells. Embodiments of the technology described herein comprise compositions, kits, vectors, and methods related to generating or engineering endothelial niche cells. One aspect comprises a method to generate/engineer endothelial niche cells, comprising expressing one or more transcription factors in an endothelial cell, wherein the one or more transcription factors are from the Ets family, the Sox family, and/or the Nuclear Hormone (NHR) family. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 17/040421 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/44 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/069 (20130101) Original (OR) Class C12N 15/907 (20130101) C12N 2501/60 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146168 | Kranzusch et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Philip J. Kranzusch (Brighton, Massachusetts); John J. Mekalanos (Newton, Massachusetts); Aaron T. Whiteley (Brookline, Massachusetts); Wen Zhou (Boston, Massachusetts) |
| ABSTRACT | The present invention is based, in part, on the discovery of the human-specific regulatory control of cGAS and the structure of the active human cGAS-DNA complex, as well as compositions comprising the modified hcGAS polypeptide, hcGAS-DNA complex, hcGAS-DNA-ATP complex, and methods of screening for modulators of the structure, expression, and/or activity of such polypeptides and complexes. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 17/252454 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Peptides C07K 2299/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1241 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146186 | Dekker et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Presidents and Fellows of Harvard University (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); Whitehead Institute for Biomedical Research (Cambridge, Massachusetts); University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Job Dekker (Princeton, Massachusetts); Erez Lieberman Aiden (Cambridge, Massachusetts); Nynke Van Berkum (NW Den Haag, Netherlands); Andreas Gnirke (Wellesley, Massachusetts); Eric Lander (Cambridge, Massachusetts); Chad Nusbaum (Newton, Massachusetts); Louise Williams (Reading, Massachusetts); Alexandre Melnikov (Bellingham, Massachusetts); Georgia Giannoukos (Cambridge, Massachusetts) |
| ABSTRACT | The disclosed Hi-C protocol can identify genomic loci that are spatially co-located in vivo. These spatial co-locations may include, but are not limited to, intrachromosomal interactions and/or interchromosomal interactions. Hi-C techniques may be applied to many different scales of interest. For example, on a large scale, Hi-C techniques can be used to identify long-range interactions between distant genomic loci. |
| FILED | Tuesday, August 11, 2020 |
| APPL NO | 16/990543 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6837 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146193 | Chidambaran et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | Vidya Chidambaran (Cincinnati, Ohio); Senthilkumar Sadhasivam (Mason, Ohio); Hong Ji (Cincinnati, Ohio); Lisa Martin (West Chester, Ohio) |
| ABSTRACT | The disclosure relates to methods for pain management in the perioperative context, particularly through the use of the DNA methylation status of the human OPRM1 gene as a biomarker for increased susceptibility to perioperative pain, and related methods and compositions. |
| FILED | Tuesday, March 07, 2023 |
| APPL NO | 18/179607 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146196 | Emery et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Caroline Emery (Kansas City, Missouri); Rajee Antony (Norwood, Massachusetts); Levi A. Garraway (Newton, Massachusetts) |
| ABSTRACT | Nucleic acids and proteins having a mutant C-RAF sequence, and methods of identifying patients having cancer who are likely to benefit from a combination therapy and methods of treatment are provided. |
| FILED | Monday, September 11, 2023 |
| APPL NO | 18/464360 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 207/11001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146197 | Parveen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Nikhat Parveen (West Orange, New Jersey); Salvatore A. Marras (Roselle Park, New Jersey) |
| ABSTRACT | The present invention provides novel methods of diagnosing and determining treatment strategies for Lyme disease and other tick-borne illnesses. |
| FILED | Wednesday, April 06, 2022 |
| APPL NO | 17/658201 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6883 (20130101) C12Q 2600/16 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146199 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Genyan Yang (Tucker, Georgia); Charles Todd Davis (Decatur, Georgia) |
| ABSTRACT | Disclosed herein are methods for detecting presence of a target nucleic acid (such as an influenza virus nucleic acid) in a sample. In some embodiments, the methods include contacting the sample with a first probe capable of hybridizing to the target nucleic acid and a second probe capable of hybridizing to the target nucleic acid, contacting the resulting complex with one or more gap filling reagents, thereby producing a gap-filled target nucleic acid, isolating and amplifying the gap-filled target nucleic acid. The amplified gap-filled target nucleic acid covalently linked to the substrate is then detected, for example with a detectably labeled probe. Also disclosed herein are probes capable of hybridizing to influenza virus nucleic acids. The disclosure also includes kits for detecting and/or discriminating influenza virus nucleic acids in a sample. In some examples, the kits include two or more of the disclosed probes. |
| FILED | Monday, December 20, 2021 |
| APPL NO | 17/555862 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) C12Q 1/686 (20130101) C12Q 1/701 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 1/6816 (20130101) C12Q 1/6816 (20130101) C12Q 2525/155 (20130101) C12Q 2531/113 (20130101) C12Q 2537/143 (20130101) C12Q 2563/143 (20130101) C12Q 2565/1015 (20130101) C12Q 2600/16 (20130101) C12Q 2600/112 (20130101) C12Q 2600/156 (20130101) C12Q 2600/166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146790 | Arbab et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| INVENTOR(S) | Mohammad Hassan Arbab (South Setauket, New York); Zachery Harris (Stony Brook, New York) |
| ABSTRACT | Handheld, broadband terahertz (THz) scanners, housings therefor and imaging systems are provided. The scanner may comprise a 2-Dimensional (2D) gimbaled mirror for beam steering. The 2D gimbaled mirror may comprise a single mirror mounted in a frame, a first motor and a second motor. The first motor and the second motor may be coupled to the frame. The mirror may be rotatable in a first axis of rotation and a second axis of rotation to scan light on a target in two dimensions. The first motor corresponds to the first axis and the second motor corresponding to the second axis. The 2D gimbaled mirror may be positioned within the housing such that the single mirror is positioned at a focus of a focusing lens. The focusing lens may be fixed within a housing. The scanner may also comprise a terahertz emitter and detector. |
| FILED | Wednesday, March 11, 2020 |
| APPL NO | 17/438630 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/021 (20130101) Original (OR) Class G01J 3/0208 (20130101) G01J 3/0272 (20130101) G01J 3/0291 (20130101) G01J 2003/062 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3586 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146836 | Tao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Nongjian Tao (Fountain Hills, Arizona); Di Wang (Tempe, Arizona); Chenwen Lin (Tempe, Arizona) |
| ABSTRACT | A micro-colorimetric sensor for sensing target chemicals using edge tracking includes a substrate. A plurality of parallel linear channels of porous media is entrenched into the substrate and each linear channel includes a sensing material adapted to sense one of several specific target chemicals in air. The plurality of parallel linear channels is separated by barrier material from the adjacent parallel linear channel where the barrier material blocks diffusion of chemicals from one linear channel to another. A plate is affixed over the substrate top to cover the plurality of parallel linear channels. An air sample is diffused along the micro-colorimetric sensor and color images are captured. An intensity profile is derived from the plurality of color images to determine a maximum and a minimum intensity value along the sensor. A plurality of positions along the sensor is tracked to determine an edge position. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 17/681128 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/783 (20130101) Original (OR) Class G01N 33/0037 (20130101) G01N 33/0039 (20130101) G01N 33/0047 (20130101) G01N 2021/7763 (20130101) G01N 2021/7793 (20130101) G01N 2201/0621 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146874 | Martin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| INVENTOR(S) | Stuart S. Martin (Severna Park, Maryland); Christopher Jewell (Silver Spring, Maryland); James Andorko (Delran, New Jersey); Elisabeth Sooklal (Reisterstown, Maryland); Rebecca Whipple Bettes (Elkridge, Maryland); Kristi Chakrabarti (Silver Spring, Maryland) |
| ABSTRACT | The present invention provides a method for imaging microtentacles on isolated, living, non-adherent primary tumor cells from a cancer subject comprising: i) obtaining one or more living, non-adherent primary tumor cells that has been isolated from a solid tumor from the subject; and ii) imaging the one or more living, non-adherent primary tumor cells and detecting the microtentacles. |
| FILED | Friday, April 03, 2015 |
| APPL NO | 15/301587 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/95 (20130101) G01N 33/50 (20130101) G01N 33/574 (20130101) G01N 33/5026 (20130101) Original (OR) Class G01N 2800/7028 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146887 | Mizokami et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE (Tokyo, Japan); SYSMEX CORPORATION (Kobe, Japan) |
| ASSIGNEE(S) | NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE (Tokyo, Japan); SYSMEX CORPORATION (Kobe, Japan) |
| INVENTOR(S) | Masashi Mizokami (Ichikawa, Japan); Masaya Sugiyama (Ichikawa, Japan); Norio Ohmagari (Shinjuku-ku, Japan); Noriko Kinoshita (Shinjuku-ku, Japan); Youichi Takahama (Kobe, Japan); Kazuki Nakabayashi (Kobe, Japan) |
| ABSTRACT | Disclosed is a method for assisting prediction of exacerbation of respiratory infection, comprising measuring a biomarker in a specimen collected from a subject suffering from a respiratory infection or a subject suspected of having a respiratory infection, wherein the biomarker is at least one selected from the group consisting of IFNλ3, CCL17, CXCL11, IP-10, IL-6 and CXCL9, and a measured value of the biomarker is used as an index to predict exacerbation of the respiratory infection. |
| FILED | Thursday, April 15, 2021 |
| APPL NO | 17/231209 |
| ART UNIT | 1678 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/537 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 33/56983 (20130101) G01N 2333/54 (20130101) G01N 2333/70535 (20130101) G01N 2333/70596 (20130101) G01N 2800/50 (20130101) G01N 2800/122 (20130101) G01N 2800/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12147022 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Ji-Xin Cheng (Newton, Massachusetts); Celalettin Yurdakul (Brighton, Massachusetts); Haonan Zong (Allston, Massachusetts); M. Selim Ünlü (Newton, Massachusetts) |
| ABSTRACT | Microscopic analysis of a sample includes a system using dark-field illumination. A mid-IR optical source generates a mid-infrared beam, which is directed onto the sample to induce a temperature change by absorption of the mid-infrared beam. A visible light source generates a light illuminating the sample on a substrate and creating a scattered field and a reflected field along a collection path of the system. A pupil mask is positioned along the collection path to block the reflected field while allowing the scattered field to pass therethrough. A camera is positioned at an end of the collection path to collect the scattered field and generate a dark-field image of the sample. |
| FILED | Friday, June 02, 2023 |
| APPL NO | 18/205152 |
| ART UNIT | 2481 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) Original (OR) Class G02B 21/025 (20130101) G02B 21/361 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12148529 | Levin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Scott R. Levin (Baltimore, Maryland); Thomas Kirsch (Baltimore, Maryland); Matthew Toerper (Cockeysville, Maryland); Gabor D. Kelen (Baltimore, Maryland); Andrea Dugas (Silver Spring, Maryland) |
| ABSTRACT | An embodiment in accordance with the present invention provides a system that uses simple standardized patient information routinely collected at triage to distribute patients amongst triage levels based on critical and time-sensitive outcomes. The present invention estimates the probability of electronic medical record (EMR) recorded events for patients at triage. Predictions are made for patients based upon clinical information routinely collected at triage which include demographics (age and gender), vital signs (temperature, heart rate, systolic blood pressure, respiratory rate, and oxygen saturation), complaint(s), medical/surgical history, chronic conditions, and mode of arrival. Vital signs are categorized as normal or gradations of abnormal. |
| FILED | Monday, August 19, 2019 |
| APPL NO | 16/544016 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/01 (20230101) G06N 20/00 (20190101) G06N 20/20 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12144642 | Barton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Jennifer Barton (Tucson, Arizona); Urs Utzinger (Tucson, Arizona); Tyler Tate (Tucson, Arizona); Maureen Keenan (Tucson, Arizona); John Forbes Black (Bainbridge Island, Washington) |
| ABSTRACT | A falloposcope is described, and a method of screening a patient for fallopian tube and/or ovarian cancer with the falloposcope. The falloposcope can perform optical imaging, including fluorescence imaging and/or optical coherence tomography (OCT), and optionally include a channel for a sampling wire, within a diameter of about 0.7 millimeter. The method includes inserting the falloposcope through a lumen of vagina, cervix, uterus, and fallopian tube so a tip of the falloposcope is in proximity to a first fallopian tube or ovary of the patient; providing fluorescence stimulus wavelength through an illumination fiber of the falloposcope while imaging light at fluorescence emission wavelength through a coherent fiber bundle to form fluorescence emissions images; and determining suspect tissue. Then the sampling wire is used to collect cells from the suspect tissue for karyotype and other analysis. |
| FILED | Monday, March 08, 2021 |
| APPL NO | 17/195221 |
| ART UNIT | 3798 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/05 (20130101) A61B 1/07 (20130101) A61B 1/0057 (20130101) A61B 1/063 (20130101) A61B 1/0125 (20130101) A61B 1/303 (20130101) A61B 5/0066 (20130101) A61B 5/0084 (20130101) A61B 5/4325 (20130101) Original (OR) Class A61B 10/04 (20130101) A61B 10/0291 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144667 | Tichauer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | The Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Kenneth M. Tichauer (Chicago, Illinois); Scott C. Davis (Woodville, New Hampshire); Brian William Pogue (Hanover, New Hampshire) |
| ABSTRACT | An apparatus and method for medical imaging uses a first and second contrast agent, the second agent targeted to a particular tissue type. First images are obtained using the first agent, and second images using the second agent using medical imaging systems. An image processing system is adapted to process the first and second medical images by fitting parameters of a pharmacokinetic model to the first medical images, identifying a nontargeted tissue type, scaling the fitted parameters to best match the nontargeted tissue in the second medical images, executing the pharmacokinetic model to prepare a correction image, and generating corrected medical images by subtracting the correction image from the second medical images. |
| FILED | Monday, November 13, 2023 |
| APPL NO | 18/389128 |
| ART UNIT | 3797 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 6/032 (20130101) A61B 6/037 (20130101) A61B 6/481 (20130101) Original (OR) Class A61B 6/4417 (20130101) A61B 6/5235 (20130101) A61B 6/5247 (20130101) Image Data Processing or Generation, in General G06T 5/50 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/20224 (20130101) G06T 2207/30024 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145127 | Leventis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aspen Aerogels, Inc. (Northborough, Massachusetts) |
| ASSIGNEE(S) | Aspen Aerogels, Inc. (Northborough, Massachusetts) |
| INVENTOR(S) | Nicholas Leventis (Worcester, Massachusetts); Chariklia Sotiriou-Leventis (Rolla, Missouri); Malik Adnan Saeed (Rolla, Missouri) |
| ABSTRACT | The present invention discloses novel porous polymeric compositions comprising random copolymers of amides, imides, ureas, and carbamic-anhydrides, useful for the synthesis of monolithic bimodal microporous/macroporous carbon aerogels. It also discloses methods for producing said microporous/macroporous carbon aerogels by the reaction of a polyisocyanate compound and a polycarboxylic acid compound, followed by pyrolytic carbonization, and by reactive etching with CO2 at elevated temperatures. Also disclosed are methods for using the microporous/macroporous carbon aerogels in the selective capture and sequestration of carbon dioxide. |
| FILED | Monday, October 04, 2021 |
| APPL NO | 17/493306 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 2253/102 (20130101) B01D 2257/504 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/0065 (20130101) B01J 13/0091 (20130101) B01J 20/20 (20130101) Original (OR) Class B01J 20/3078 (20130101) B01J 20/3085 (20130101) B01J 20/28042 (20130101) B01J 20/28047 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/00 (20170801) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 18/346 (20130101) C08G 18/7664 (20130101) C08G 2110/0091 (20210101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/36 (20130101) C08J 9/286 (20130101) C08J 2201/0543 (20130101) C08J 2205/05 (20130101) C08J 2205/026 (20130101) C08J 2205/044 (20130101) C08J 2205/048 (20130101) C08J 2375/02 (20130101) C08J 2375/04 (20130101) C08J 2377/00 (20130101) C08J 2379/08 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 3/104 (20130101) C10L 2290/542 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 20/20 (20130101) Y02C 20/40 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145703 | Seeley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| INVENTOR(S) | Eric Seeley (Seebeck, Washington); Jacob Snow (Bremerton, Washington) |
| ABSTRACT | A system for releasable attachment mechanisms comprising modular elements and attachable components, including a male end adapted to join a single-piece female end by rotating the male end into the single-piece female end such that data bus terminals align and power bus terminals align. The system can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed systems for each mission. The joints connecting the modules are designed such that power and data connections between modules are reliably made. |
| FILED | Tuesday, July 11, 2023 |
| APPL NO | 18/220796 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/04 (20130101) Original (OR) Class B63G 2008/002 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/91 (20130101) H01R 12/7005 (20130101) H01R 13/64 (20130101) H01R 13/641 (20130101) H01R 13/6205 (20130101) H01R 13/7175 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145912 | Miao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Lei Miao (San Jose, California); Linxian Li (Malden, Massachusetts); Daniel Griffith Anderson (Framingham, Massachusetts); Yuxuan Huang (Cambridge, United Kingdom) |
| ABSTRACT | Provided herein are lipidoid compounds of Formulae (I) and (II), and pharmaceutically acceptable salts, co-crystals, tautomers, stereoisomers, solvates, hydrates, polymorphs, isotopically labeled derivatives, prodrugs, and compositions thereof. Also provided are methods and kits involving the inventive lipidoid compounds, compositions, or formulations for treating and/or preventing diseases (e.g., genetic disease, proliferative disease, hematological disease, neurological disease, painful condition, psychiatric disorder, metabolic disorder, long-term medical condition, inflammatory disease, autoinflammatory disease, liver disease, lung disease, spleen disease, familial amyloid neuropathy, cardiovascular disease, viral infection, infectious disease, fibrotic condition, or autoimmune disease) in a subject, methods for synthesizing the compounds described herein, and compounds described herein synthesized by the synthetic methods described herein. The compounds are effective carriers for the delivery of an agent such as a polynucleotide (e.g., RNA) to a cell. |
| FILED | Thursday, July 28, 2022 |
| APPL NO | 17/875982 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39 (20130101) A61K 2039/53 (20130101) A61K 2039/55555 (20130101) Acyclic or Carbocyclic Compounds C07C 237/06 (20130101) C07C 251/08 (20130101) Heterocyclic Compounds C07D 233/40 (20130101) Original (OR) Class C07D 403/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145918 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Loon-Seng Tan (Centerville, Ohio); Zhenning Yu (Beavercreek, Ohio) |
| ABSTRACT | Applicants disclose a family of rod-like dianhydrides that contain two phthalic anhydride moieties linked by a bridge that is comprised of at least one ethynyl and one paraphenylene group and processes of making and using such rod-like dianhydrides. Such rod-like dianhydrides can endow net-work structures with improved mechanical and thermal properties in the crosslinked-polymer products. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/299092 |
| ART UNIT | 4111 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 307/89 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145966 | Matoba |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (Louisville, Kentucky) |
| INVENTOR(S) | Nobuyuki Matoba (Owensboro, Kentucky) |
| ABSTRACT | Polypeptides are provided that include an actinohivin variant polypeptide. The actinohivin variant polypeptide can be operably connected to an antibody fragment, such as a fragment crystallizable (Fc) region of immunoglobulin (Ig) G. Nucleic acid sequences, expression vectors, and transformed plant cells useful for producing the polypeptides are also provided. Further provided are methods for treating a viral infection or a cancer in a subject and include the step of administering the actinohivin variant polypeptide to the subject. |
| FILED | Friday, February 09, 2018 |
| APPL NO | 16/485021 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) A61P 11/00 (20180101) A61P 31/18 (20180101) A61P 35/00 (20180101) A61P 35/04 (20180101) Peptides C07K 14/36 (20130101) Original (OR) Class C07K 2319/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8258 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146071 | Snyder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERPHASE MATERIALS INC. (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Interphase Materials Inc. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Noah Snyder (Glenshaw, Pennsylvania); Kasey Catt (Pittsburgh, Pennsylvania); Natasha Gorski (Pittsburgh, Pennsylvania) |
| ABSTRACT | A surface treatment includes a functional component and a linking component, wherein the linking component is capable of hydrogen bonding and/or covalently linking with the functional component and is capable of hydrogen bonding and/or covalently linking with the surface to form a treated surface. The surface treatment provides a beneficial property to the surface when the surface treatment is bonded to the surface. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/639169 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 7/225 (20130101) B05D 2202/15 (20130101) B05D 2202/45 (20130101) B05D 2518/10 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/14 (20130101) C08G 77/24 (20130101) C08G 77/26 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 183/06 (20130101) Original (OR) Class C09D 183/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146093 | Peterson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia); South Dakota School of Mines (Rapid City, South Dakota) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia); South Dakota School of Mines (Rapid City, South Dakota) |
| INVENTOR(S) | G. P. “Bud” Peterson (Atlanta, Georgia); Haiping Hong (Rapid City, South Dakota) |
| ABSTRACT | The present invention relates to thermal materials and methods of making the same. Disclosed herein is a thermal material, comprising: a boron-containing nanomaterial; and a thermal fluid operable to hydrogen bond with the boron-containing nanomaterial; wherein the thermal material presents an increase in thermal conductivity over the pure thermal fluid by an amount of 30% or greater. Also disclosed herein are methods for making a thermal material. |
| FILED | Friday, May 10, 2019 |
| APPL NO | 17/054359 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/10 (20130101) Original (OR) Class C09K 5/14 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) H01B 1/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146413 | Heeter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce North American Technologies Inc. (Indianapolis, Indiana) |
| INVENTOR(S) | Robert W. Heeter (Indianapolis, Indiana); William B. Bryan (Indianapolis, Indiana); Daniel E. Molnar, Jr. (Indianapolis, Indiana); Gregory J. Hebert (Indianapolis, Indiana) |
| ABSTRACT | A fan duct assembly includes a bypass duct, an outlet guide vane assembly, and a flow control system. The bypass duct has an outer wall and an inner wall that define a gas path for bypass air therebetween. The outlet guide vane assembly is coupled with the bypass duct and includes a plurality of vanes. The flow control system is configured to direct selectively a portion of the bypass air flowing through the gas path radially into each of the plurality of vanes. |
| FILED | Tuesday, December 12, 2023 |
| APPL NO | 18/537071 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/105 (20130101) Original (OR) Class F01D 17/162 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/60 (20130101) F05D 2240/128 (20130101) F05D 2260/606 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146762 | Wichowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Keith C Wichowski (Portsmouth, Rhode Island); Zachary D Sawyer (North Kingstown, Rhode Island); Daniel T Savaria (Bristol, Rhode Island); Patrick B Ryll (Tiverton, Rhode Island) |
| ABSTRACT | An object tracking system includes objects being tracked that have a communication means. The objects can be in either periodic or continuous communication. A receiver is capable of receiving data from the objects. A processor and database are provided joined to the receiver. The processor updates the database with the received positional data, and linked time data for each object. The processor and database are also capable of sorting the historic positional data, planned positional data, and current positional data by the time data linked to the position data to generate sorted positional data. A display is joined to the processor to receive and display the sorted positional data and linked time data. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/098824 |
| ART UNIT | 3665 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3841 (20200801) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/87 (20130101) Electric Digital Data Processing G06F 16/29 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146807 | Walters et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sunrise International, Inc. (Marietta, Georgia) |
| ASSIGNEE(S) | Sunrise International, Inc. (Marietta, Georgia) |
| INVENTOR(S) | Craig T. Walters (Powell, Ohio); David Sokol (Dublin, Ohio) |
| ABSTRACT | Systems, methods and device provided for combining or splitting laser beams, including a plurality of optical fibers for providing laser beams, an image relay lens for each of the plurality of optical fibers, positioning a prism beam combiner or splitter after the image relay lenses for combining or splitting the laser beams. According to another aspect, the a prism beam combiner or splitter may include a flattened tip to transmit a portion of an input laser beam, a position sensitive detector to receive the transmitted portion of the input laser beam to track a beam axis motion and provide feedback alignment error signals based on the beam axis motion, and a driver to receive the feedback alignment error signals and to drive a motor or piezo actuated beam steering minor based on the feedback alignment error signals, wherein a laser bond inspection method implements the described systems and methods. |
| FILED | Tuesday, October 01, 2019 |
| APPL NO | 17/281627 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 11/37 (20130101) G01M 11/088 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 19/04 (20130101) G01N 29/043 (20130101) G01N 29/2412 (20130101) G01N 29/2418 (20130101) G01N 2291/0231 (20130101) Optical Elements, Systems, or Apparatus G02B 6/04 (20130101) G02B 6/32 (20130101) G02B 6/4214 (20130101) G02B 6/4296 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146874 | Martin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| INVENTOR(S) | Stuart S. Martin (Severna Park, Maryland); Christopher Jewell (Silver Spring, Maryland); James Andorko (Delran, New Jersey); Elisabeth Sooklal (Reisterstown, Maryland); Rebecca Whipple Bettes (Elkridge, Maryland); Kristi Chakrabarti (Silver Spring, Maryland) |
| ABSTRACT | The present invention provides a method for imaging microtentacles on isolated, living, non-adherent primary tumor cells from a cancer subject comprising: i) obtaining one or more living, non-adherent primary tumor cells that has been isolated from a solid tumor from the subject; and ii) imaging the one or more living, non-adherent primary tumor cells and detecting the microtentacles. |
| FILED | Friday, April 03, 2015 |
| APPL NO | 15/301587 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/95 (20130101) G01N 33/50 (20130101) G01N 33/574 (20130101) G01N 33/5026 (20130101) Original (OR) Class G01N 2800/7028 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146876 | Ramsey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | John Michael Ramsey (Chapel Hill, North Carolina); William Hampton Henley (Chapel Hill, North Carolina); Thomas Linz (Chapel Hill, North Carolina) |
| ABSTRACT | Decoding methods are provided for identifying populations in assays, particularly multiplexing assays and those associated with fluidic devices. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244257 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/542 (20130101) Original (OR) Class G01N 33/54313 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146953 | Xia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | X-Wave Innovations, Inc. (Gaithersburg, Maryland) |
| ASSIGNEE(S) | X-Wave Innovations, Inc. (Gaithersburg, Maryland) |
| INVENTOR(S) | Lang Xia (Gaithersburg, Maryland); Dan Xiang (Gaithersburg, Maryland) |
| ABSTRACT | Some embodiments relate to the application of a system and a signal processing method for data acquired from a Scanning Acoustic Microscope (SAM) to obtain a high axial resolution and enhanced imaging. The SAM is one of ultrasound imaging methods used for NDE. Embodiments may provide methods for decreasing or reducing the duration (width) of the pulses scattered/reflected by multiple objects/scatters. Such embodiments can accomplish this by eliminating, or at least partially eliminating, the background noise by deconvolving the system responses (i.e., reference signals) obtained from either theoretical modeling or experimental acquiring. In one embodiment, the method minimizes the pulse duration by using a regression technique to predict the spectra responses outside a frequency band. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 17/459292 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/46 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/8977 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 5/10 (20130101) G06T 5/20 (20130101) G06T 5/70 (20240101) G06T 2207/10056 (20130101) G06T 2207/10132 (20130101) G06T 2207/20182 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12147026 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Magic Leap, Inc. (Plantation, Florida) |
| ASSIGNEE(S) | Magic Leap, Inc. (Plantation, Florida) |
| INVENTOR(S) | Chunyu Gao (Tucson, Arizona); Yuxiang Lin (Tucson, Arizona); Hong Hua (Tucson, Arizona) |
| ABSTRACT | The present invention comprises a compact optical see-through head-mounted display capable of combining, a see-through image path with a virtual image path such that the opaqueness of the see-through image path can be modulated and the virtual image occludes parts of the see-through image and vice versa. |
| FILED | Tuesday, April 04, 2023 |
| APPL NO | 18/295685 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 13/06 (20130101) G02B 25/001 (20130101) G02B 26/00 (20130101) Original (OR) Class G02B 27/144 (20130101) G02B 27/0172 (20130101) G02B 27/283 (20130101) G02B 27/1066 (20130101) G02B 2027/015 (20130101) G02B 2027/0118 (20130101) G02B 2027/0145 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 37/02 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Pictorial Communication, e.g Television H04N 23/45 (20230101) H04N 23/698 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12147284 | Paquette et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MITRE Corporation (Bedford, Massachusetts) |
| ASSIGNEE(S) | MITRE Corporation (Bedford, Massachusetts) |
| INVENTOR(S) | Michael J. Paquette (Bedford, Massachusetts); Brian D. Marquis (Bedford, Massachusetts); Rachel Bainbridge (Bedford, Massachusetts); Joe Chapman (Bedford, Massachusetts) |
| ABSTRACT | Power and electromagnetic fault injection vulnerabilities in an integrated circuit (IC) can be characterized sampling one or more integrated timing sensors in real-time or by equivalent-time sampling. To achieve equivalent-time sampling, a series of fault injection attempts are performed. An array of timing sensors implemented in part of the IC capture a measure of relative propagation delay, which fluctuates proportionally with instantaneous voltage. Increased voltage fluctuation can indicate elevated probability of faults in digital logic. Related apparatus, systems, techniques and articles are also described. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/706186 |
| ART UNIT | 2114 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/30 (20130101) Original (OR) Class G06F 11/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12147382 | Valmus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | William David Valmus (Rockville, Maryland); Chelsea M. Gibson (Albuquerque, New Mexico); David S. Sracic (Gaithersburg, Maryland) |
| ABSTRACT | Exemplary practice of the present invention assimilates information from various commercial software scanning tools. Distinctive characteristics pertaining to the construction and constitution of the different software items are gathered and tracked. A practitioner is thus afforded the capability of, for instance, generating customized dashboards to present the assimilated information. The data obtained are considered to describe different data types and different data formats. Among the inventive features is a normalization of every data format to a standard data format as part of the analytical methodology. The resultant universalization of the database can be facilitative with respect to a variety of ways in which the database may be utilized. |
| FILED | Sunday, September 11, 2022 |
| APPL NO | 17/942156 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/75 (20130101) G06F 11/3466 (20130101) G06F 16/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12147407 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas); University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Zichao Wang (Houston, Texas); Shiting Lan (Boston, Massachusetts); Richard G. Baraniuk (Houston, Texas) |
| ABSTRACT | A method for processing formulae includes encoding a formula by: training, with a server, a model by using a machine learning algorithm with a data set that includes a plurality of formulae; transforming, with a processor, a first formula into a tree format using the trained model; converting, with the processor, the tree format of the first formula into a plurality of lists; and encoding, with the processor, the plurality of lists into a fixed dimension vector by leveraging a stacked attention module; and generating one or more formula candidates by: obtaining, with the processor, input information; and generating, with the processor, one or more second formula candidates based on input information by using the stacked attention module with a tree beam search algorithm. |
| FILED | Friday, April 21, 2023 |
| APPL NO | 18/305220 |
| ART UNIT | 2154 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2246 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12147476 | Macker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Joseph Macker (Washington, District of Columbia); Michael Iannelli (Washington, District of Columbia) |
| ABSTRACT | Systems and methods are provided for a hypergraph representation and transformation process enabling the cogeneration and analysis of multiple system attributes alongside system node relationships within real world data models. Embodiments of the present disclosure allow for the cogeneration of attribute embeddings, along with node embeddings, within a single, graph-based data set model. Embodiments of the present disclosure provide a higher level of accuracy in problem space representation compared to conventional systems and methods and help to reveal more complex relationships in real world problems. |
| FILED | Saturday, September 30, 2023 |
| APPL NO | 18/375504 |
| ART UNIT | 2161 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/906 (20190101) G06F 16/9024 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12147900 | Narain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Perspecta Labs Inc. (Basking Ridge, New Jersey) |
| ASSIGNEE(S) | Peraton Labs Inc. (Basking Ridge, New Jersey) |
| INVENTOR(S) | Sanjai Narain (Basking Ridge, New Jersey); Emily Chun Mak (Basking Ridge, New Jersey) |
| ABSTRACT | In a computer-implemented method, computer program product, and computer system, program code executing on a processor(s) generates input-output pairs, to form a training set for machine learning and generates a machine learning model of a cyber physical system by utilizing a machine learning algorithm and the training set to train the machine learning model. The program code converts the trained machine learning model into an equivalent constraint and optimizes objective functions subject to the constraint by utilizing one or more constraint solvers to compute an input-output pair. The program code determines if the computed input-output pair, is within an error tolerance and based on determining that it is, either utilizes it as a solution or adds it to the training set (and continues training). If the pair is not within the tolerance, the program code utilizes it as a solution or adds it to the training set (and continues training). |
| FILED | Friday, December 13, 2019 |
| APPL NO | 16/713779 |
| ART UNIT | 2126 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/082 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12148136 | Indeck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph Stephen Indeck (Huntsville, Alabama); Kavan Hazeli (Tucson, Arizona); Jesus O. Mares (Mary Esther, Florida) |
| ASSIGNEE(S) | Board of Trustees for the University of Alabama, for and on behalf of the University of Alabama in Huntsville (Huntsville, Alabama); Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Joseph Stephen Indeck (Huntsville, Alabama); Kavan Hazeli (Tucson, Arizona); Jesus O. Mares (Mary Esther, Florida) |
| ABSTRACT | An image processing system receives a digital image and analyzes the digital image to determine a resolution limit, referred to herein as “feature resolution,” for measuring a metric for features of the image within an acceptable margin of error. Specifically, the system segments a digital image and calculates the error associated with the segmented data when features within a certain range a measured metric (e.g., size range) are removed from the segmented data. This analysis can be repeatedly performed with different cutoff values for the metric until at least a threshold amount of error is reached, thereby indicating a resolution limit at the boundary of an acceptable amount of error. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/671527 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0002 (20130101) Original (OR) Class G06T 7/11 (20170101) G06T 7/60 (20130101) G06T 2207/20076 (20130101) G06T 2207/30168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12148194 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intelligent Fusion Technology, Inc. (Germantown, Maryland) |
| ASSIGNEE(S) | Intelligent Fusion Technology, Inc. (Germantown, Maryland) |
| INVENTOR(S) | Hua-mei Chen (Germantown, Maryland); Ashley Diehl (Dayton, Ohio); Erik Blasch (Arlington, Virginia); Genshe Chen (Germantown, Maryland) |
| ABSTRACT | Embodiments of the present disclosure provide a method, a device, and a storage medium for targeted adversarial discriminative domain adaptation (T-ADDA). The method includes pre-training a source model including a source feature encoder and a source classifier, adapting a target feature encoder, and generating a target model by concatenating the adapted target feature encoder with the pre-trained source classifier. Adapting the target feature encoder includes configuring the pre-trained source feature encoder to be an initial target feature encoder for generating target feature vectors in each target class; adjusting a domain discriminator according to an adversarial domain discrimination loss; adjusting the initial target feature encoder according to a generative adversarial network (GAN) loss; and further adjusting the initial target feature encoder to generate the target feature encoder according to a feature class matching loss using labeled target feature vectors and corresponding source feature class centers. |
| FILED | Tuesday, September 14, 2021 |
| APPL NO | 17/474516 |
| ART UNIT | 2681 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/44 (20220101) Original (OR) Class G06V 10/764 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12148536 | Nelson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Centre National De La Recherche Scientifique (Paris, France) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (Paris, France) |
| INVENTOR(S) | Keith Nelson (Newton, Massachusetts); Steven Kooi (Lexington, Massachusetts); Thomas Pezeril (Le Mans, France) |
| ABSTRACT | In some embodiments, a method to excite a shock wave in a target assembly includes: splitting a pulsed laser beam into a plurality of pulsed laser beams; spatially shaping the plurality of pulsed laser beams into a plurality of concentric pulsed laser rings of different diameters; and adjusting temporal and/or spatial intervals between the concentric pulsed laser rings to substantially match propagation times of a ring-shaped laser-driven shock wave from one ring to the next in a shock propagation layer of the target assembly. |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/066909 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Fusion Reactors G21B 1/03 (20130101) G21B 1/19 (20130101) G21B 1/23 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12148748 | Iyer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Subramanian Iyer (Los Angeles, California); Kannan K. Thankappan (Los Angeles, California); Boris Vaisband (Los Angeles, California) |
| ABSTRACT | Two approaches for on-chip ESD detection include variable dielectric width capacitor, and vertical metal-oxide-semiconductor (MOS) capacitor MOSCAP array. The variable dielectric width capacitor approach employs metal plates terminated with sharp corners to enhance local electric field and facilitate ready breakdown of a thin dielectric between the metal plates. The vertical MOSCAP array is composed of a capacitor array connected in series. Both approaches are incorporated in an example 22 nm fully depleted silicon-on-insulator. Vertical MOSCAP arrays detect ESD events starting from about 6 V with about 6 V granularity, while the variable dielectric width capacitor is suitable for detection of high ESD voltage from about 40 V and above. |
| FILED | Thursday, May 27, 2021 |
| APPL NO | 17/332931 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/01 (20130101) H01L 27/0805 (20130101) Original (OR) Class H01L 28/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12149038 | Baker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Colin C. Baker (Alexandria, Virginia); Edward J. Friebele (Cheverly, Maryland); Woohong Kim (Lorton, Virginia); L. Brandon Shaw (Woodbridge, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
| ABSTRACT | Methods for synthesizing fibers having nanoparticles therein are provided, as well as preforms and fibers incorporating nanoparticles. The nanoparticles may include one or more rare earth ions selected based on fluorescence at eye-safer wavelengths, surrounded by a low-phonon energy host. Nanoparticles that are not doped with rare earth ions may also be included as a co-dopant to help increase solubility of nanoparticles doped with rare earth ions in the silica matrix. The nanoparticles may be incorporated into a preform, which is then drawn to form fiber. The fibers may beneficially be incorporated into lasers and amplifiers that operate at eye safer wavelengths. Lasers and amplifiers incorporating the fibers may also beneficially exhibit reduced Stimulated Brillouin Scattering. |
| FILED | Tuesday, June 22, 2021 |
| APPL NO | 17/354466 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Manufacture, Shaping, or Supplementary Processes C03B 37/01208 (20130101) C03B 37/01262 (20130101) C03B 2201/34 (20130101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 13/04 (20130101) C03C 13/045 (20130101) C03C 14/006 (20130101) C03C 2214/16 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/169 (20130101) H01S 3/176 (20130101) H01S 3/1603 (20130101) H01S 3/06716 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12149142 | Miesner |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John E. Miesner (Fairfax, Virginia) |
| ABSTRACT | Electromagnetic inertial force generators are provided, which include radially polarized permanent magnets providing bias flux across axial gaps to combine with axial coil flux to linearize the actuator output. Coil cooling in the electromagnetic inertial force generators is improved by embedding the coils in the stationary portion of the actuator, allowing for direct transfer of coil heat, and reducing oscillating stresses on coil leads. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/684967 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 3/24 (20130101) H02K 33/06 (20130101) H02K 33/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12149278 | Dafesh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | Philip A. Dafesh (Manhattan Beach, California); Phillip Brian Hess (Venice, California); Gourav K. Khadge (Los Angeles, California) |
| ABSTRACT | Provided herein are circuits and methods for processing samples of a received in-phase and quadrature (I/Q) domain signal that includes a desired signal and an interference signal that spectrally overlaps the desired signal. In the I/Q domain, a first contribution to the interference signal is removed from the samples using a first algorithm to generate first processed signal samples. Amplitudes and phases of the first processed signal samples are obtained. In an amplitude domain, a second contribution to the interference signal is removed from the amplitudes of the first processed signal samples using a second algorithm to generate second processed signal samples. A signal quality metric of the second processed signal samples is obtained. Based on the signal quality metric of the second processed signal samples, one or more parameters of the first or second algorithm are adjusted to improve the signal quality metric of the second processed signal samples. |
| FILED | Tuesday, February 07, 2023 |
| APPL NO | 18/165594 |
| ART UNIT | 2635 — Electrical Circuits and Systems |
| CURRENT CPC | Transmission H04B 1/719 (20130101) H04B 1/1027 (20130101) H04B 1/1036 (20130101) H04B 1/7107 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12149293 | Dets et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LaserMotive, Inc. (Kent, Washington) |
| ASSIGNEE(S) | LaserMotive, Inc. (Kent, Washington) |
| INVENTOR(S) | Sergiy Dets (Calgary, Canada); Thomas J. Nugent, Jr. (Bellevue, Washington) |
| ABSTRACT | A reflector assembly at a power beam receiver includes at least two sets of reflection surfaces positioned to shift some incoming light away from the center of the beam and towards the periphery. These surfaces may be positioned obliquely to one another, for example orthogonally. By shifting a portion of the power beam away from a higher-intensity center and toward a lower-intensity periphery, the reflector assembly may improve receiver efficiency without substantial redirection of power outside of a power-collecting surface of the receiver. |
| FILED | Friday, November 11, 2022 |
| APPL NO | 18/054867 |
| ART UNIT | 2634 — Digital Communications |
| CURRENT CPC | Transmission H04B 10/808 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12149296 | Harwood, II et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | KELLOGG BROWN and ROOT LLC (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Theodore Leonard Harwood, II (Hollywood, Maryland); Jerick Craig Black (Lexington Park, Maryland) |
| ABSTRACT | The described systems and related test methods provide significant improvement in test accuracy, as well as reduction of test time for Electromagnetic Environmental Effects (E3) system level testing. Systems may include a real time spectrum analyzer, a network analyzer, and a switching/filtering/coupling network controlled by an information processing device, such as a general purpose computer. These systems can scan all frequencies at each receiver. |
| FILED | Thursday, March 24, 2022 |
| APPL NO | 17/703842 |
| ART UNIT | 2465 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 17/21 (20150115) H04B 17/27 (20150115) H04B 17/29 (20150115) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12149342 | Lazzaro et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Matthew Lazzaro (Churchville, Maryland); William Toth (Ocean, New Jersey) |
| ABSTRACT | Various embodiments are described that relate to random noise addition to a communication. A first secure network can employ a first encryption scheme and a second secure network can employ a second encryption scheme. In order to communicate between the first secure network and the second secure network such that the schemes are not decipherable, random noise can be added to a communication designated to transfer from the first secure network to the second secure network. |
| FILED | Monday, June 26, 2023 |
| APPL NO | 18/213910 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Secret Communication; Jamming of Communication H04K 1/00 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 2209/80 (20130101) Wireless Communication Networks H04W 12/03 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150319 | Fuentes-Hernandez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Canek Fuentes-Hernandez (Atlanta, Georgia); Wen-Fang Chou (Atlanta, Georgia); Xiaojia Jia (Atlanta, Georgia); Bernard Kippelen (Atlanta, Georgia) |
| ABSTRACT | Provided is a semiconductor device having a dual gate field-effect transistor and a sensor in electrical communication with the transistor. The field-effect transistor can have a first gate electrode, a second gate electrode, a source electrode, a drain electrode, a semiconductor layer with parts in contact with the source and drain electrodes, a bi-layer gate insulator, and a second gate insulator. The bi-layer gate insulator can include a first layer and a second layer, the first layer located between the second layer and a first side of the semiconductor layer, the second layer located between the first layer and the first gate electrode. The second gate insulator can be located between the second gate electrode and a second side of the semiconductor layer, and the sensor can be in electrical communication with the second gate electrode. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 17/429334 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Organic electric solid-state devices H10K 10/476 (20230201) H10K 10/482 (20230201) Original (OR) Class H10K 19/10 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12145081 | Robinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | David Bruce Robinson (Hayward, California); Maher Salloum (Livermore, California) |
| ABSTRACT | A fluid flow control device comprising an insert body having a first portion with a first permeability and second portion with a second permeability that is different from the first permeability. The insert body can be shaped for sealing insertion into a fluid flow structure for fluid flow therethrough. The first portion and the second portion can be arranged in the insert body to cause uniform fluid flow velocity of fluid in the fluid flow structure at an exit of the insert body when the fluid passes through the first portion and the second portion when the insert body is placed inside the fluid flow structure. |
| FILED | Tuesday, January 26, 2021 |
| APPL NO | 17/158115 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/22 (20130101) Original (OR) Class B01D 35/157 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145701 | Lynn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Other Lab, LLC (San Francisco, California) |
| ASSIGNEE(S) | OTHER LAB, LLC (San Francisco, California) |
| INVENTOR(S) | Peter Sturt Lynn (Alameda, California); Jonathan B. Pompa (Long Beach, California) |
| ABSTRACT | An anchor installation vehicle that includes a vehicle frame having a top end and bottom end, one or more rotational thrusters, and an anchor system configured to hold an anchor extending from the bottom end of the vehicle frame. |
| FILED | Tuesday, December 13, 2022 |
| APPL NO | 18/080491 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 21/20 (20130101) B63B 21/26 (20130101) B63B 79/10 (20200101) B63B 79/40 (20200101) Original (OR) Class Marine Propulsion or Steering B63H 11/00 (20130101) Foundations; Excavations; Embankments; Underground or Underwater Structures E02D 5/801 (20130101) E02D 7/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145962 | Felsenstein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Kenneth Felsenstein (Denver, Colorado); Dan Theodorescu (Englewood, Colorado); Ryan T. Gill (Denver, Colorado) |
| ABSTRACT | Provided herein, in some embodiments, are methods and compositions for gene editing using a trackable gene library, for example, a barcoded and gene edited library. |
| FILED | Monday, February 04, 2019 |
| APPL NO | 16/966339 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/64 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/08 (20130101) C40B 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146168 | Kranzusch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Philip J. Kranzusch (Brighton, Massachusetts); John J. Mekalanos (Newton, Massachusetts); Aaron T. Whiteley (Brookline, Massachusetts); Wen Zhou (Boston, Massachusetts) |
| ABSTRACT | The present invention is based, in part, on the discovery of the human-specific regulatory control of cGAS and the structure of the active human cGAS-DNA complex, as well as compositions comprising the modified hcGAS polypeptide, hcGAS-DNA complex, hcGAS-DNA-ATP complex, and methods of screening for modulators of the structure, expression, and/or activity of such polypeptides and complexes. |
| FILED | Wednesday, June 26, 2019 |
| APPL NO | 17/252454 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/13 (20130101) Peptides C07K 2299/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1241 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146233 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Meng Li (Ammon, Idaho); Bin Hua (Ammon, Idaho); Dong Ding (Idaho Falls, Idaho) |
| ABSTRACT | A method of hydrogenating carbon dioxide comprises forming a tunable catalyst comprising at least one metal comprising a size within a range of from a single atom to about 999 nanometers and formulated to produce one or more carbon-containing compounds. An electrochemical cell comprising a positive electrode, a negative electrode comprising the tunable catalyst, and an electrolyte between the positive electrode and the negative electrode is formed. Carbon dioxide is introduced to the negative electrode of the electrochemical cell and a potential difference is applied between the positive electrode and the negative electrode to selectively hydrogenate the carbon dioxide. The hydrogen ions are diffused through the electrochemical cell. The carbon dioxide at the negative electrode is hydrogenated to selectively form carbon monoxide, methane, or a desired ratio of carbon monoxide and methane. An electrochemical cell and a carbon dioxide hydrogenation system are also disclosed. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 17/445685 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/23 (20210101) C25B 1/50 (20210101) C25B 3/03 (20210101) C25B 3/26 (20210101) Original (OR) Class C25B 9/17 (20210101) C25B 11/052 (20210101) C25B 11/069 (20210101) C25B 11/081 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146234 | Feaster et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jeremy Taylor Feaster (Fremont, California); Sarah Baker (Dublin, California); Daniel Corral (Fremont, California); Eric Duoss (Dublin, California) |
| ABSTRACT | System and method relates to an advanced manufactured vapor-fed electrochemical reactor (AM-VFR) system comprising a cathode gas compartment comprising a first inlet, and a first outlet, a catholyte compartment having a centrally located window for a cathode and a membrane, a second inlet, a second outlet, and a reference electrode, an anolyte compartment having a centrally located window for the membrane and an anode, a third inlet and a third outlet and an anode gas compartment having a fourth inlet and a fourth outlet, wherein the cathode, wherein the cathode is disposed between the cathode gas compartment and the catholyte compartment, wherein the membrane is disposed between the catholyte compartment and the anolyte compartment, wherein the anode is disposed between the anolyte compartment and the anode gas compartment, and wherein one or more of the cathode gas compartment, the catholyte compartment, the anolyte compartment and the anode gas compartment are made of a 3D printing plastic. Methods for making and using the system are also disclosed. |
| FILED | Wednesday, September 02, 2020 |
| APPL NO | 17/010680 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 80/00 (20141201) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 1/01 (20210101) C25B 1/23 (20210101) C25B 1/50 (20210101) C25B 1/135 (20210101) C25B 3/26 (20210101) C25B 9/19 (20210101) C25B 9/63 (20210101) Original (OR) Class C25B 11/04 (20130101) C25B 11/055 (20210101) C25B 11/075 (20210101) C25B 15/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146242 | Naskar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Amit K. Naskar (Knoxville, Tennessee); Connie D. Jackson (Harriman, Tennessee) |
| ABSTRACT | A method of producing carbon fibers includes the step of providing polyacrylonitrile precursor polymer fiber filaments. The polyacrylonitrile precursor filaments include from 87-97 mole % acrylonitrile, and less than 0.5 mole % of accelerant functional groups. The filaments are no more than 3 deniers per filament. The polyacrylonitrile precursor fiber filaments can be arranged into tows of at least 150,000 deniers per inch width. The arranged polyacrylonitrile precursor fiber tows are stabilized by heating the tows in at least one oxidation zone containing oxygen gas and maintained at a first temperature T1 while stretching the tows at least 10% to yield a stabilized precursor fiber tow. The stabilized precursor fiber tows are carbonized by passing the stabilized precursor fiber tows through a carbonization zone. Carbon fibers produced by the process are also disclosed. |
| FILED | Tuesday, March 09, 2021 |
| APPL NO | 17/196964 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 9/225 (20130101) Original (OR) Class D01F 9/328 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146711 | Hu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| INVENTOR(S) | Liangbing Hu (Rockville, Maryland); Xizheng Wang (Greenbelt, Maryland); Xinpeng Zhao (Berwyn Heights, Maryland); Hua Xie (Greenbelt, Maryland) |
| ABSTRACT | A sintering furnace can have a housing, one or more heating elements, and a conveying assembly. Each heating element can be disposed within the housing and can subject a heating zone to a thermal shock temperature profile. A substrate with one or more precursors thereon can be moved by the conveying assembly through an inlet of the housing to the heating zone, where it is subjected to a first temperature of at least 500° C. for a first time period. The conveying assembly can then move the substrate with one or more sintered materials thereon from the heating zone and through an outlet of the housing. |
| FILED | Friday, March 25, 2022 |
| APPL NO | 18/283782 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Furnaces, Kilns, Ovens, or Retorts in General; Open Sintering or Like Apparatus F27B 1/12 (20130101) F27B 1/22 (20130101) F27B 1/26 (20130101) F27B 9/02 (20130101) F27B 9/063 (20130101) Original (OR) Class F27B 2009/124 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146774 | Gee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Richard H. Gee (Livermore, California); Amitesh Maiti (San Ramon, California); Henry E. Reinstein (Livermore, California); Alexander David Wilson (Danville, California); Peter J. Zischka (Livermore, California) |
| ABSTRACT | A system for determining particle size of a quantity of a sample material contained in a sample material holder is disclosed, where the sample material is made up a plurality of the particles. The system may incorporate a pressure regulating subsystem for receiving a first pressurized airflow signal and regulating the first pressurized airflow signal to a second pressurized airflow signal having a pressure lower than the first pressurized airflow signal, the second pressurized airflow signal configured to be input to a first end of the sample material holder. A mass airflow transducer may be incorporated for determining a flow rate representing an air flow value entering the sample material holder. A control module uses the air flow value in combination with the pressure differential value and mathematically determining a dimension of the particles making up the sample material. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/017271 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/88 (20130101) G01F 1/363 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/02 (20130101) G01N 15/082 (20130101) Electric Digital Data Processing G06F 17/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146995 | Burghard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Brion J. Burghard (West Richland, Washington); William G. Bennett (West Richland, Washington); Kurt L. Silvers (Pasco, Washington); Anton S. Sinkov (Richland, Washington); Erik S. Simunds (Kennewick, Washington); Andrei B. Valsan (Richland, Washington); Sean D. McGaughey (West Richland, Washington) |
| ABSTRACT | Radiation monitoring devices and associated methods are described. According to one aspect, a radiation monitoring device includes a housing configured to pass radiation emitted from a radiological source located in proximity to the radiation monitoring device, a radiation detector configured to receive the radiation emitted from the radiological source and to generate information regarding the radiation, and communications circuitry configured to communicate the information regarding the radiation in a plurality of communications at a plurality of different moments in time externally of the radiation monitoring device. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/537205 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 1/17 (20130101) Original (OR) Class Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 5/06 (20130101) G21F 5/12 (20130101) G21F 5/015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12147512 | Suski |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Applied Engineering Concepts, Inc. (Eldersburg, Maryland) |
| ASSIGNEE(S) | Applied Engineering Concepts, Inc. (Eldersburg, Maryland) |
| INVENTOR(S) | William Charles Suski (Mount Pleasant, South Carolina) |
| ABSTRACT | Systems and methods for computing device authentication can involve template matching with an authentication filter. Authentication filters can be generated by using an authentication model to determine or generate templates for authenticated classes. For example, simulated signal data sets can be input into the authentication model until an authenticated class classification is output. The successful simulated signal data set may then be used to generate or update an authentication filter that uses the template for template matching authentication classification. |
| FILED | Friday, May 27, 2022 |
| APPL NO | 17/826654 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/31 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12148537 | Jiang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Energy, United States Department of (Washington, District of Columbia) |
| ASSIGNEE(S) | Energy, United States Department of (Washington, District of Columbia) |
| INVENTOR(S) | Junhua Jiang (Idaho Falls, Idaho) |
| ABSTRACT | A liquid metal cooled molten salt reactor having a liquid metal vessel connected to a gas chamber that is connected to a molten salt chamber that is connected with a hot liquid metal vessel. A fuel salt that is withdrawn from the fuel salt tank through a feeding tube into the molten salt chamber from which the fuel salt is withdrawn into a salt separator. A purging gas is inserted into the gas chamber and withdrawn. A liquid metal coolant is dispensed from the liquid metal vessel through a plurality of dispensing nozzles into the molten salt chamber. The liquid metal coolant flows through the molten salt into a hot liquid metal vessel and then through a liquid metal filter into a liquid metal pump. The liquid metal coolant flows through a thermal exchanger subsequently returning to the liquid metal vessel. |
| FILED | Tuesday, August 03, 2021 |
| APPL NO | 17/392599 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Nuclear Reactors G21C 3/54 (20130101) G21C 15/28 (20130101) G21C 15/247 (20130101) Original (OR) Class G21C 19/307 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12148538 | van Rooyen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Isabella J. van Rooyen (Idaho Falls, Idaho); Piyush Sabharwall (Idaho Falls, Idaho) |
| ABSTRACT | Methods of placing sensors in structures may involve placing first particles including a first material of the structure on or above a support surface. Second particles including a second, different material may be dispersed among the first particles at least within a transition region of the structure proximate to a location where a sensor is to be supported by the structure. A sensor may be placed in the location. The first particles of the first material may be fused to one another and to the second particles of the second material to form the structure with the sensor supported by the structure. |
| FILED | Thursday, November 05, 2020 |
| APPL NO | 17/089922 |
| ART UNIT | 1759 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/28 (20210101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 1/02 (20130101) Nuclear Reactors G21C 17/102 (20130101) Original (OR) Class G21C 17/112 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/473 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12148888 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Zhengcheng Zhang (Naperville, Illinois); Noah Mark Johnson (Westmont, Illinois) |
| ABSTRACT | An electrochemical device includes an electrolyte having a hydroxamate or N-hydroxyamide compound. |
| FILED | Wednesday, April 12, 2023 |
| APPL NO | 18/133668 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 259/10 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/054 (20130101) H01M 10/0567 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12149070 | Hong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HITACHI ENERGY LTD (Zürich, Switzerland); ABB Schweiz AG (Baden, China PRC) |
| ASSIGNEE(S) | Hitachi Energy Ltd. (Zurich, Switzerland) |
| INVENTOR(S) | Junho Hong (Cary, North Carolina); Dmitry Ishchenko (Cary, North Carolina); Reynaldo Nuqui (Cary, North Carolina) |
| ABSTRACT | Systems, methods, techniques and apparatuses of nested microgrids are disclosed. One exemplary embodiment is a method for removing false data in a nested microgrid system, the method comprising: calculating a first local state estimation using a first plurality of local measurements and a second local state estimation using a second plurality of local measurements; calculating, with a central control system, a plurality of global state estimations including a first global state estimation a second global state estimation; performing a first false data detection test using the first local state estimation and one global state estimation of the plurality of global state estimations; performing a second false data detection test using the first global state estimation and the second global state estimation; detecting false data; and updating the first global state estimation, the second global state estimation, or the first local state estimation in response to detecting the false data. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/147979 |
| ART UNIT | 2147 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 22/066 (20130101) Electric Digital Data Processing G06F 30/18 (20200101) G06F 30/20 (20200101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 13/00002 (20200101) Original (OR) Class H02J 13/00016 (20200101) H02J 13/00022 (20200101) H02J 2203/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12149096 | Zhang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Bo Zhang (Salt Lake City, Utah) |
| ABSTRACT | Active electromagnetic shielding for dynamic high power wireless charging and related electrified roadway systems, method, and wireless power transmitters is disclosed. A wireless power transmitter includes a first canceling coil offset from a power transmission coil, a second canceling coil offset from the power transmission coil, and circuitry electrically connected to the first canceling coil and the second canceling coil. The circuitry is configured to deliver canceling currents to the first canceling coil and the second canceling coil to destructively interfere with portions of electromagnetic fields generated by the power transmission coil. |
| FILED | Thursday, September 10, 2020 |
| APPL NO | 17/753533 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 53/12 (20190201) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/05 (20160201) H02J 50/12 (20160201) Original (OR) Class H02J 50/40 (20160201) H02J 50/70 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150248 | Hatch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Jonathan Douglas Hatch (Cleveland, Missouri); Stephen McGarry Hatch (Blue Springs, Missouri) |
| ABSTRACT | A system for providing selective adhesion printed circuit board (PCB) production comprises a conveyor mechanism, a curing system, and a computer. The conveyor mechanism is configured to convey a series of selective adhesion blanks, wherein each selective adhesion blank is utilized to produce a PCB and includes a flexible film, a substrate, a conductive layer, and a curable adhesive. The conductive layer is formed from electrically conductive material and adhered to the substrate. The curable adhesive is positioned between the flexible film and the conductive layer and is configured to selectively bond with the conductive layer when the curable adhesive is cured. The curing system is configured to cure the curable adhesive. The computer includes a processing element configured or programmed to: receive a plurality of PCB designs, and direct the curing system to cure the curable adhesive of a plurality of selective adhesion blanks for each PCB design. |
| FILED | Thursday, September 01, 2022 |
| APPL NO | 17/901417 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 3/00 (20130101) H05K 3/0005 (20130101) H05K 3/108 (20130101) H05K 3/386 (20130101) H05K 3/1283 (20130101) Original (OR) Class H05K 3/4691 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150319 | Fuentes-Hernandez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Canek Fuentes-Hernandez (Atlanta, Georgia); Wen-Fang Chou (Atlanta, Georgia); Xiaojia Jia (Atlanta, Georgia); Bernard Kippelen (Atlanta, Georgia) |
| ABSTRACT | Provided is a semiconductor device having a dual gate field-effect transistor and a sensor in electrical communication with the transistor. The field-effect transistor can have a first gate electrode, a second gate electrode, a source electrode, a drain electrode, a semiconductor layer with parts in contact with the source and drain electrodes, a bi-layer gate insulator, and a second gate insulator. The bi-layer gate insulator can include a first layer and a second layer, the first layer located between the second layer and a first side of the semiconductor layer, the second layer located between the first layer and the first gate electrode. The second gate insulator can be located between the second gate electrode and a second side of the semiconductor layer, and the sensor can be in electrical communication with the second gate electrode. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 17/429334 |
| ART UNIT | 2899 — Semiconductors/Memory |
| CURRENT CPC | Organic electric solid-state devices H10K 10/476 (20230201) H10K 10/482 (20230201) Original (OR) Class H10K 19/10 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150321 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (, None) |
| INVENTOR(S) | Jongchan Kim (Ann Arbor, Michigan); Stephen R. Forrest (Ann Arbor, Michigan) |
| ABSTRACT | An organic electronic device comprises a substrate, at least one morphological stabilizing layer positioned over the substrate, the morphological stabilizing layer comprising a material having a Tg greater than 50° C., and at least one organic layer positioned in direct contact with the morphological stabilizing layer. A method of making an organic electronic device is also disclosed. |
| FILED | Wednesday, November 17, 2021 |
| APPL NO | 17/528821 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Organic electric solid-state devices H10K 10/486 (20230201) H10K 30/865 (20230201) Original (OR) Class H10K 50/11 (20230201) H10K 71/00 (20230201) H10K 2102/351 (20230201) H10K 2102/361 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12144630 | Makeyev |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Diné College (Tsaile, Arizona) |
| ASSIGNEE(S) | DINÉ COLLEGE (Tsaile, Arizona) |
| INVENTOR(S) | Oleksandr Makeyev (Tsaile, Arizona) |
| ABSTRACT | A concentric ring electrode (CRE) is provided that can sense characteristics of an electric potential, such as its Laplacian, more accurately than previous systems. The disclosed system and methods can optimize estimates of the Laplacian based on potentials measured by the CRE's electrodes, and can optimize the geometry of the CRE, in particular the ring electrodes' radii. Given the CRE's geometrical configuration, the system estimates the Laplacian's dependence on the measured potentials by computing a null space of a matrix associated with a series expansion of the potential. The system determines coefficients for the dependence, wherein a first coefficient is between −10 and 10 times, or between −6.5 and −7.5 times, a second coefficient. The system can optimize ranges for the radii by canceling at least one truncation term of the series expansion, estimating a higher-order truncation term as a function of the radii, and minimizing this estimated function. |
| FILED | Monday, May 20, 2019 |
| APPL NO | 16/417422 |
| ART UNIT | 2896 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/291 (20210101) Original (OR) Class A61B 5/4094 (20130101) A61B 2562/125 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/04 (20130101) A61N 1/0531 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49002 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144716 | MacEwan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Matthew R. MacEwan (St. Louis, Missouri); Jingwei Xie (St. Louis, Missouri); Zack Ray (St. Louis, Missouri); Younan Xia (St. Louis, Missouri) |
| ABSTRACT | A multi-laminar electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers, and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is combined with the first layer. A first portion of the scaffold includes a higher density of fibers than a second portion of the scaffold, and the first portion has a higher tensile strength than the second portion. The scaffold is configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The scaffold is configured to be applied to the tissue substrate containing the defect, and is sufficiently flexible to facilitate application of the scaffold to uneven surfaces of the tissue substrate, and to enable movement of the scaffold by the tissue substrate. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/358463 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/02 (20130101) Original (OR) Class A61F 2/0063 (20130101) A61F 2/105 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/22 (20130101) A61L 15/42 (20130101) A61L 27/14 (20130101) A61L 27/50 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/05 (20190201) B29C 48/142 (20190201) Apparatus for Enzymology or Microbiology; C12M 25/14 (20130101) Mechanical Methods or Apparatus in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons D01D 5/0076 (20130101) D01D 5/0092 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/728 (20130101) D04H 3/016 (20130101) D04H 3/073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144772 | Gregg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Robert D. Gregg (Allen, Texas); Ge Lv (Dallas, Texas) |
| ABSTRACT | Total energy shaping control methods and devices for powered orthosis for controlling the device to counteract forces exerted on the person including inertial forces. |
| FILED | Monday, May 21, 2018 |
| APPL NO | 16/615495 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/11 (20130101) A61B 5/0057 (20130101) A61B 5/112 (20130101) A61B 5/6812 (20130101) A61B 5/6828 (20130101) A61B 5/6829 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 5/0102 (20130101) A61F 2005/0155 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 1/024 (20130101) A61H 1/0244 (20130101) A61H 1/0262 (20130101) Original (OR) Class A61H 1/0266 (20130101) A61H 3/00 (20130101) A61H 2201/1207 (20130101) A61H 2201/1472 (20130101) A61H 2201/5061 (20130101) A61H 2201/5064 (20130101) A61H 2201/5069 (20130101) A61H 2201/5084 (20130101) A61H 2205/10 (20130101) A61H 2205/12 (20130101) A61H 2230/625 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/0006 (20130101) B25J 9/126 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145216 | Bassett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Lee Bassett (Wallingford, Pennsylvania); Samuel Parks (Philadelphia, Pennsylvania); Richard Grote (Los Angeles, California); David Hopper (Philadelphia, Pennsylvania) |
| ABSTRACT | A laser is used to controllably generate and propagate cleaves to produce a cleaved surface along the {111} crystallographic plane in diamonds. |
| FILED | Tuesday, May 15, 2018 |
| APPL NO | 16/613410 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/53 (20151001) Original (OR) Class B23K 26/082 (20151001) B23K 26/402 (20130101) B23K 2103/50 (20180801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145267 | Ramani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Karthik Ramani (West Lafayette, Indiana); Ke Huo (Unico City, California); Yuanzhi Cao (Redmond, Washington); Tianyi Wang (West Lafayette, Indiana) |
| ABSTRACT | A system and method for authoring and performing Human-Robot-Collaborative (HRC) tasks is disclosed. The system and method adopt an embodied authoring approach in Augmented Reality (AR), for spatially editing the actions and programming the robots through demonstrative role-playing. The system and method utilize an intuitive workflow that externalizes user's authoring as demonstrative and editable AR ghost, allowing for spatially situated visual referencing, realistic animated simulation, and collaborative action guidance. The system and method utilize a dynamic time warping (DTW) based collaboration model which takes the real-time captured motion as inputs, maps it to the previously authored human actions, and outputs the corresponding robot actions to achieve adaptive collaboration. |
| FILED | Wednesday, September 16, 2020 |
| APPL NO | 17/022216 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1605 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145311 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Yong Chen (Los Angeles, California); Huachao Mao (Los Angeles, California) |
| ABSTRACT | A method of multi-material 3D printing is performed by an apparatus comprising at least one printhead device; a build platform; a light source; and a computing unit comprising a non-transitory computer-readable medium encoded with program instructions for controlling the at least one printhead device; the build platform; and the light source to perform the method of multi-material 3D printing. In various embodiments, each printhead device comprises a coating section, a curing section, a cleaning section, and optionally, a post-curing section. Each printhead device is configured to perform each of these steps, with the multiple printheads engaged in fabricating a multi-material part layer-by-layer. |
| FILED | Monday, October 18, 2021 |
| APPL NO | 17/504169 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/25 (20170801) B29C 64/35 (20170801) B29C 64/135 (20170801) Original (OR) Class B29C 64/209 (20170801) B29C 64/232 (20170801) B29C 64/236 (20170801) B29C 64/245 (20170801) B29C 64/255 (20170801) B29C 64/268 (20170801) B29C 64/286 (20170801) B29C 64/336 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145316 | Zhong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Ying Zhong (Tampa, Florida); Zijian Weng (Temple Terrace, Florida) |
| ABSTRACT | This invention relates to a method and apparatus for creating a three-dimensional structure from a binder-free powder. A corona discharge (plasma) generator forms a controllable electric field, positioning the binder-free powder within the influence of the electric field generated by the corona discharge generator, and activating the corona discharge generator to attract the binder-free powder into a three-dimensional structure. The corona discharge generator includes a grounded bottom substrate and a top substrate elevated above the bottom substrate in a substantially parallel planar orientation. The binder-free powder is placed in the interstitial space between the bottom substrate and the top substrate. An electrode above the top substrate, in electrical communication with the bottom substrate and coupled to a voltage power supply, creates the electrical field. The resulting three-dimensional structure is formed far more rapidly than known additive manufacturing techniques. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/121054 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/153 (20170801) B29C 64/264 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 1/47 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145816 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Daeyeon Lee (Wynnewood, Pennsylvania); Kathleen Stebe (Penn Valley, Pennsylvania); Shu Yang (Blue Bell, Pennsylvania); Xu Zhang (Claymont, Delaware) |
| ABSTRACT | Provided are systems and methods for inducing strain fields to give rise to controllable wrinkle patterns in a variety of substrates. Also provided are articles having persistent wrinkling patterns thereon. |
| FILED | Friday, May 24, 2019 |
| APPL NO | 17/053909 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Handling Thin or Filamentary Material, e.g Sheets, Webs, Cables B65H 37/02 (20130101) Original (OR) Class B65H 2301/51145 (20130101) B65H 2701/124 (20130101) B65H 2701/172 (20130101) B65H 2801/87 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/0236 (20130101) H01L 31/02168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12145870 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Jianfeng Zhou (Atlanta, Georgia); Xing Xie (Atlanta, Georgia) |
| ABSTRACT | An exemplary embodiment of the present invention provides a system for disinfecting a fluid, the system comprising: an outer electrode defining an internal cavity; a center electrode comprising a plurality of surface area members, the center electrode positioned within the internal cavity and extending along at least a portion of a longitudinal axis of the outer electrode; an inlet positioned proximate a first end of the outer electrode and configured to allow a fluid to pass from an area external to the cavity into the cavity; and an outlet positioned proximate a second end of the outer electrode and configured to allow the fluid to pass from the cavity into an area external to the cavity. A voltage supply can be configured to supply a voltage across the outer electrode and center electrode, the voltage generating a non-uniform electric field distribution on a cross-sectional plane of the system. |
| FILED | Wednesday, February 05, 2020 |
| APPL NO | 16/782430 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/46109 (20130101) Original (OR) Class C02F 2001/46133 (20130101) C02F 2001/46171 (20130101) C02F 2101/30 (20130101) C02F 2201/46105 (20130101) C02F 2303/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146732 | Meeks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lumina Instruments Inc. (San Jose, California) |
| ASSIGNEE(S) | Lumina Instruments Inc. (San Jose, California) |
| INVENTOR(S) | Steven W. Meeks (Palo Alto, California); Hung Phi Nguyen (Santa Clara, California); Alireza Shahdoost Moghaddam (San Jose, California) |
| ABSTRACT | An optical scanning system includes a radiating source capable of outputting a source light beam, a de-scan lens that is configured to output a de-scanned light beam, the de-scan lens is located approximately one focal length of the de-scan lens from an sample irradiation location, a focusing lens that is configured to output a focused light beam, a first non-polarizing beam splitter configured to be irradiated by at least a portion of the focused light beam, a second non-polarizing beam splitter configured to be irradiated by at least a portion of the focused light beam that is reflected by the first non-polarizing beam splitter, and a detector that is located at approximately one focal length of the focusing lens from the focusing lens, the detector is configured to be irradiated by at least a portion of the focused light beam that is not reflected by the second non-polarizing beam splitter. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 17/685706 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146750 | Masoud |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Neda Masoud (Dexter, Michigan) |
| ABSTRACT | A ride-sourcing method including receiving a plurality of ride-sourcing requests; grouping a first set of the plurality of ride-sourcing requests into a first cluster and a second set of the plurality of ride-sourcing requests into a second cluster; computing a tour formation for each of the first cluster and the second cluster to define a series of stations and a cost function; applying trips to the first cluster and the second cluster under uniformity constraints; repeating the computing and applying steps until the cost function between consecutive iterations is below a threshold to define a first cluster of trips and a second cluster of trips; and assigning the first cluster of trips to a first driver and the second cluster of trips to a second driver. |
| FILED | Tuesday, June 28, 2022 |
| APPL NO | 17/851577 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3438 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/047 (20130101) G06Q 50/40 (20240101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146830 | Meeks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lumina Instruments Inc. (San Jose, California) |
| ASSIGNEE(S) | Lumina Instruments Inc. (San Jose, California) |
| INVENTOR(S) | Steven W. Meeks (Palo Alto, California); Hung Phi Nguyen (Santa Clara, California); Alireza Shahdoost Moghaddam (San Jose, California) |
| ABSTRACT | An optical scanning system including a radiating source capable of outputting a source light beam, a de-scan lens that is configured to output a de-scanned light beam, the de-scanned light beam is created by focusing light reflected from the sample and the de-scan lens is located approximately one focal length of the de-scan lens from an irradiation location where the light beam irradiates the sample, a focusing lens that is configured to output a focused light beam, a collimating lens that is configured to output a collimated light beam, a polarizing beam splitter that is configured to be irradiated by the collimated light beam, and a detector that is configured to be irradiated by at least a portion of the collimated light beam that is not reflected by the polarizing beam splitter. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 17/685719 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) Original (OR) Class G01N 2201/021 (20130101) G01N 2201/0633 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146851 | Mousavi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Seyedeh Moloud Mousavi (Watertown, Massachusetts); George M. Whitesides (Newton, Massachusetts) |
| ABSTRACT | Fabrication of a low-cost and miniaturized solid-contact thread-based ion sensing electrode (ISE) that is suitable for point-of-care applications is described. The fabrication process is simple and scalable. Different types of threads and a variety of different conductive ion-to-electron transducer inks can be used to fabricate the thread-based ISEs with Nernstian responses. Multiple thread-based sensors can be easily bundled with the reference electrode to fabricate a customized sensor for multiplexed ion-sensing in small sample volumes. The thread-based electrodes can be used in both single-use and reusable fashion. The thread-based multiplexed ion-sensor is used for detection of a wide array of ions in many different types of aqueous solutions. |
| FILED | Tuesday, November 13, 2018 |
| APPL NO | 16/762821 |
| ART UNIT | 1789 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/404 (20130101) D02G 3/441 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/333 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12147033 | Meeks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lumina Instruments Inc. (San Jose, California) |
| ASSIGNEE(S) | Lumina Instruments Inc. (San Jose, California) |
| INVENTOR(S) | Steven W. Meeks (Palo Alto, California); Hung Phi Nguyen (Santa Clara, California); Alireza Shahdoost Moghaddam (San Jose, California) |
| ABSTRACT | An optical scanning system includes a radiating source capable of outputting a source light beam, a de-scan lens that is configured to output a de-scanned light beam, the de-scan lens is located approximately one focal length of the de-scan lens from a sample irradiation location, a focusing lens that is configured to output a focused light beam, a first non-polarizing beam splitter configured to be irradiated by at least a portion of the focused light beam, a second non-polarizing beam splitter configured to be irradiated by at least a portion of the focused light beam that is reflected by the first non-polarizing beam splitter, and a detector that is located at approximately one focal length of the focusing lens from the focusing lens, the detector is configured to be irradiated by at least a portion of the focused light beam that is reflected by the second non-polarizing beam splitter. |
| FILED | Thursday, March 03, 2022 |
| APPL NO | 17/685698 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 13/0005 (20130101) G02B 13/22 (20130101) G02B 26/105 (20130101) G02B 26/123 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12147407 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas); University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Zichao Wang (Houston, Texas); Shiting Lan (Boston, Massachusetts); Richard G. Baraniuk (Houston, Texas) |
| ABSTRACT | A method for processing formulae includes encoding a formula by: training, with a server, a model by using a machine learning algorithm with a data set that includes a plurality of formulae; transforming, with a processor, a first formula into a tree format using the trained model; converting, with the processor, the tree format of the first formula into a plurality of lists; and encoding, with the processor, the plurality of lists into a fixed dimension vector by leveraging a stacked attention module; and generating one or more formula candidates by: obtaining, with the processor, input information; and generating, with the processor, one or more second formula candidates based on input information by using the stacked attention module with a tree beam search algorithm. |
| FILED | Friday, April 21, 2023 |
| APPL NO | 18/305220 |
| ART UNIT | 2154 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/2246 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12147806 | Tu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Yicheng Tu (Tampa, Florida); Napath Pitaksirianan (Tampa, Florida) |
| ABSTRACT | Disclosed are various embodiments for computing 2-body statistics on graphics processing units (GPUs). Various types of two-body statistics (2-BS) are regarded as essential components of data analysis in many scientific and computing domains. However, the quadratic complexity of these computations hinders timely processing of data. According, various embodiments of the present disclosure involve parallel algorithms for 2-BS computation on Graphics Processing Units (GPUs). Although the typical 2-BS problems can be summarized into a straightforward parallel computing pattern, traditional wisdom from (general) parallel computing often falls short in delivering the best possible performance. Therefore, various embodiments of the present disclosure involve techniques to decompose 2-BS problems and methods for effective use of computing resources on GPUs. We also develop analytical models that guide users towards the appropriate parameters of a GPU program. Although 2-BS problems share the same core computations, each 2-BS problem however carries its own characteristics that calls for different strategies in code optimization. Accordingly, various embodiments of the present disclosure involve a software framework that automatically generates high-performance GPU code based on a few parameters and short primer code input. |
| FILED | Tuesday, February 07, 2023 |
| APPL NO | 18/165589 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30043 (20130101) G06F 9/30098 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12149560 | Riahi Manesh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of North Dakota (Grand Forks, North Dakota) |
| ASSIGNEE(S) | University of North Dakota (Grand Forks, North Dakota) |
| INVENTOR(S) | Mohsen Riahi Manesh (Grand Forks, North Dakota); Naima Kaabouch (Grand Forks, North Dakota) |
| ABSTRACT | The present subject matter provides various technical solutions to technical problems facing ADS-B cyber-attacks. One technical solution for detecting and mitigating ADS-B cyber-attacks includes receiving extracting information from received ADS-B signals, detecting a cyber-attack based on a selected subset of ADS-B information, determining a detection probability, and outputting a ADS-B cyber-attack type and probability. This solution may further include determining and implementing a cyber-attack mitigation to reduce the probability or effect of the detected cyber-attack. These solutions operate based on current ADS-B receiver technology, and can be combined with existing ADS-B receivers to detect message injection attacks, modification attacks, and jamming attacks. The technical solutions described herein use machine learning (ML) algorithms and statistical models to detect anomalies in incoming ADS-B messages. This enables these solutions to be trained in different environments, which further improves the cyber-attack detection accuracy and reduces likelihood of false alarms or miss detections. |
| FILED | Wednesday, January 22, 2020 |
| APPL NO | 17/425395 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 18/214 (20230101) G06F 21/554 (20130101) Computer Systems Based on Specific Computational Models G06N 7/01 (20230101) G06N 20/00 (20190101) G06N 20/20 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/20 (20130101) H04L 63/1416 (20130101) H04L 63/1425 (20130101) H04L 63/1458 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12149847 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gigajot Technology, Inc. (Pasadena, California) |
| ASSIGNEE(S) | Gigajot Technology, Inc. (Pasadena, California) |
| INVENTOR(S) | Jiaju Ma (Monrovia, California); Saleh Masoodian (Monrovia, California) |
| ABSTRACT | Correlated double sampling column-level readout of an image sensor pixel (e.g., a CMOS image sensor) may be provided by a charge transfer amplifier that is configured and operated to itself provide for both correlated-double-sampling and amplification of floating diffusion potentials read out from the pixel onto a column bus after reset of the floating diffusion (i) but before transferring photocharge to the floating diffusion (the reset potential) and (ii) after transferring photocharge to the floating diffusion (the transfer potential). A common capacitor of the charge transfer amplifier may sample both the reset potential and the transfer potential such that a change in potential (and corresponding charge change) on the capacitor represents the difference between the transfer potential and reset potential, and the magnitude of this change is amplified by the charge change being transferred between the common capacitor and a second capacitor selectively coupled to the common capacitor. |
| FILED | Wednesday, November 23, 2022 |
| APPL NO | 18/058722 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14612 (20130101) Pictorial Communication, e.g Television H04N 25/59 (20230101) H04N 25/65 (20230101) H04N 25/75 (20230101) Original (OR) Class H04N 25/616 (20230101) H04N 25/778 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12146093 | Peterson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia); South Dakota School of Mines (Rapid City, South Dakota) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia); South Dakota School of Mines (Rapid City, South Dakota) |
| INVENTOR(S) | G. P. “Bud” Peterson (Atlanta, Georgia); Haiping Hong (Rapid City, South Dakota) |
| ABSTRACT | The present invention relates to thermal materials and methods of making the same. Disclosed herein is a thermal material, comprising: a boron-containing nanomaterial; and a thermal fluid operable to hydrogen bond with the boron-containing nanomaterial; wherein the thermal material presents an increase in thermal conductivity over the pure thermal fluid by an amount of 30% or greater. Also disclosed herein are methods for making a thermal material. |
| FILED | Friday, May 10, 2019 |
| APPL NO | 17/054359 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/10 (20130101) Original (OR) Class C09K 5/14 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) H01B 1/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146969 | Hassouneh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Munther Hassouneh (Greenbelt, Maryland); Luke Winternitz (Greenbelt, Maryland); Samuel R. Price (Greenbelt, Maryland); Luke J. Thomas (Greenbelt, Maryland); Yan Lu Chen (Greenbelt, Maryland); Jason Mitchell (Greenbelt, Maryland) |
| ABSTRACT | A space based multi-band GPS/GNSS navigation system, including: RF card to receive and process the two different received navigation signals; a space grade navigation processor configured to: execute processor instructions to process the two different received navigation signals to produce position, velocity, and time information; and process measurements using a Kalman filter for enhanced performance at high altitude. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/038358 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/32 (20130101) Original (OR) Class G01S 19/37 (20130101) G01S 19/45 (20130101) G01S 19/46 (20130101) G01S 19/393 (20190801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146990 | Gill et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Nathaniel Gill (Greenbelt, Maryland); Kenneth McCaughey (Greenbelt, Maryland) |
| ABSTRACT | Various embodiments relate to a light detecting and ranging (LiDAR) system including: a space-qualified transmitter including a space-qualified microelectromechanical system (MEMS); a space-qualified receiver; a space-qualified short-range imager connected to the space-qualified receiver; a space-qualified long-range imager connected to the space-qualified receiver. |
| FILED | Tuesday, July 16, 2019 |
| APPL NO | 16/513071 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/484 (20130101) G01S 7/4813 (20130101) G01S 7/4818 (20130101) G01S 7/4861 (20130101) Original (OR) Class G01S 7/4865 (20130101) G01S 17/894 (20200101) G01S 17/933 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 12144325 | Staples et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); Animal Control Technologies (Australia) Pty Ltd (Victoria, Australia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of Agriculture (Washington, District of Columbia); Animal Control Technologies (Australia) Pty Ltd (Somerton, Australia) |
| INVENTOR(S) | Linton Drew Staples (Canterbury, Australia); Michael John Lavelle (Washington, District of Columbia); Joseph Martin Halseth (Washington, District of Columbia); Nathan Paul Snow (Washington, District of Columbia); Brendan Lake (Kennedy Town, China Hong Kong) |
| ABSTRACT | An apparatus for baiting and/or feeding target animals comprises: a trough to contain bait and/or feed; and a closure which can be urged by at least one said target animal so as to move from a closed position, in which it precludes access to the bait and/or feed by the target animal(s), to an open position, which is such that said access is enabled, the apparatus being configured such that the closure offers a resistance to being moved which is sufficient that it cannot be urged by another animal to move from the closed position to the open position. |
| FILED | Monday, August 26, 2019 |
| APPL NO | 17/270855 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 5/01 (20130101) A01K 5/025 (20130101) Original (OR) Class Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 25/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12144800 | Abel-Santos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the Nevada System of Higher Education on Behalf of the University of Nevada, Las Vegas (Las Vegas, Nevada) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (Las Vegas, Nevada) |
| INVENTOR(S) | Ernesto Abel-Santos (Las Vegas, Nevada); Norma Ramirez (Guanajuato, Mexico); Marc Liggins (Irvine, California) |
| ABSTRACT | Provided herein are materials and methods useful for reducing, preventing, and/or inhibiting germination of C. perfringens spores, including methods for inhibiting C. perfringens germination to reduce necrotizing enteritis (NE, also referred to as necrotic enteritis) in animals. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Thursday, February 04, 2021 |
| APPL NO | 17/168155 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Fodder A23K 20/195 (20160501) Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/0056 (20130101) A61K 9/1611 (20130101) A61K 31/428 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 12145597 | Jeihani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Morgan State University (Baltimore, Maryland) |
| ASSIGNEE(S) | Morgan State University (Baltimore, Maryland) |
| INVENTOR(S) | Mansoureh Jeihani (Timonium, Maryland); Samira Ahangari (Baltimore, Maryland); Abdollah Dehzangi (Baltimore, Maryland); Arsalan Hassan Pour (Baltimore, Maryland) |
| ABSTRACT | Systems and methods are disclosed for detecting both the occurrence and type of driver distraction experienced by a driver, determined through evaluation of sensed vehicle conditions or activities, such as steering, braking, lane changing, etc. as detected by one or more sensors on or associated with the vehicle. That detection of the occurrence and type of driver distraction may then be used to initiate another action, including initiating an audible or visual alert to the driver, taking measures to interfere with or stop operation of the device that is causing the distraction, log the occurrence and type of distraction that occurred, and report the occurrence and type of distraction to an outside monitoring computer (such as one associated with a guardian of the driver, an insurer of the vehicle, a law enforcement authority, or the like). To allow such detection, the system and method set forth herein employ machine learning methods to first train a classifier to classify certain driver behaviors (as evidenced by sensed vehicle movements and conditions) as a distraction or non-distraction event, and if a distraction event is detected then to further classify a type of such distraction event, and then to apply the trained classifier to classify the driver's ongoing driving activity. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/389741 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 40/02 (20130101) B60W 40/09 (20130101) Original (OR) Class B60W 50/14 (20130101) B60W 2050/143 (20130101) B60W 2050/146 (20130101) B60W 2540/30 (20130101) B60W 2540/229 (20200201) B60W 2552/00 (20200201) B60W 2756/10 (20200201) Electric Digital Data Processing G06F 18/24 (20230101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image or Video Recognition or Understanding G06V 20/597 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12146750 | Masoud |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Neda Masoud (Dexter, Michigan) |
| ABSTRACT | A ride-sourcing method including receiving a plurality of ride-sourcing requests; grouping a first set of the plurality of ride-sourcing requests into a first cluster and a second set of the plurality of ride-sourcing requests into a second cluster; computing a tour formation for each of the first cluster and the second cluster to define a series of stations and a cost function; applying trips to the first cluster and the second cluster under uniformity constraints; repeating the computing and applying steps until the cost function between consecutive iterations is below a threshold to define a first cluster of trips and a second cluster of trips; and assigning the first cluster of trips to a first driver and the second cluster of trips to a second driver. |
| FILED | Tuesday, June 28, 2022 |
| APPL NO | 17/851577 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3438 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/047 (20130101) G06Q 50/40 (20240101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 12148529 | Levin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Scott R. Levin (Baltimore, Maryland); Thomas Kirsch (Baltimore, Maryland); Matthew Toerper (Cockeysville, Maryland); Gabor D. Kelen (Baltimore, Maryland); Andrea Dugas (Silver Spring, Maryland) |
| ABSTRACT | An embodiment in accordance with the present invention provides a system that uses simple standardized patient information routinely collected at triage to distribute patients amongst triage levels based on critical and time-sensitive outcomes. The present invention estimates the probability of electronic medical record (EMR) recorded events for patients at triage. Predictions are made for patients based upon clinical information routinely collected at triage which include demographics (age and gender), vital signs (temperature, heart rate, systolic blood pressure, respiratory rate, and oxygen saturation), complaint(s), medical/surgical history, chronic conditions, and mode of arrival. Vital signs are categorized as normal or gradations of abnormal. |
| FILED | Monday, August 19, 2019 |
| APPL NO | 16/544016 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 5/01 (20230101) G06N 20/00 (20190101) G06N 20/20 (20190101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 12144788 | Palczewski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERAN AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Krzysztof Palczewski (Bay Village, Ohio); Philip Kiser (Cleveland, Ohio); Jianye Zhang (Cleveland, Ohio); Mohsen Badiee (Shaker Heights, Ohio); Gregory Tochtrop (Shaker Heights, Ohio) |
| ABSTRACT | A method of treating an ocular disorder in a subject in need thereof includes administering to the subject a therapeutically effective amount of a retinal sequestering compound of formula (I). |
| FILED | Tuesday, February 22, 2022 |
| APPL NO | 17/677524 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 31/137 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 12147026 | Gao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Magic Leap, Inc. (Plantation, Florida) |
| ASSIGNEE(S) | Magic Leap, Inc. (Plantation, Florida) |
| INVENTOR(S) | Chunyu Gao (Tucson, Arizona); Yuxiang Lin (Tucson, Arizona); Hong Hua (Tucson, Arizona) |
| ABSTRACT | The present invention comprises a compact optical see-through head-mounted display capable of combining, a see-through image path with a virtual image path such that the opaqueness of the see-through image path can be modulated and the virtual image occludes parts of the see-through image and vice versa. |
| FILED | Tuesday, April 04, 2023 |
| APPL NO | 18/295685 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/04 (20130101) G02B 13/06 (20130101) G02B 25/001 (20130101) G02B 26/00 (20130101) Original (OR) Class G02B 27/144 (20130101) G02B 27/0172 (20130101) G02B 27/283 (20130101) G02B 27/1066 (20130101) G02B 2027/015 (20130101) G02B 2027/0118 (20130101) G02B 2027/0145 (20130101) Apparatus or Arrangements for Taking Photographs or for Projecting or Viewing Them; Apparatus or Arrangements Employing Analogous Techniques Using Waves Other Than Optical Waves; Accessories Therefor G03B 37/02 (20130101) Image Data Processing or Generation, in General G06T 19/006 (20130101) Pictorial Communication, e.g Television H04N 23/45 (20230101) H04N 23/698 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
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How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 19, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20241119.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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