FedInvent™ Patents
Patent Details for Tuesday, November 26, 2024
This page was updated on Monday, December 09, 2024 at 05:57 PM GMT
Department of Health and Human Services (HHS)
| US 12150661 | Maxwell et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Adam D. Maxwell (Ann Arbor, Michigan); Zhen Xu (Ann Arbor, Michigan); Hitinder S. Gurm (Ann Arbor, Michigan); Charles A. Cain (Ann Arbor, Michigan) |
| ABSTRACT | Methods for performing non-invasive thrombolysis with ultrasound using, in some embodiments, one or more ultrasound transducers to focus or place a high intensity ultrasound beam onto a blood clot (thrombus) or other vascular inclusion or occlusion (e.g., clot in the dialysis graft, deep vein thrombosis, superficial vein thrombosis, arterial embolus, bypass graft thrombosis or embolization, pulmonary embolus) which would be ablated (eroded, mechanically fractionated, liquefied, or dissolved) by ultrasound energy. The process can employ one or more mechanisms, such as of cavitational, sonochemical, mechanical fractionation, or thermal processes depending on the acoustic parameters selected. This general process, including the examples of application set forth herein, is henceforth referred to as “Thrombolysis.” |
| FILED | Monday, June 05, 2023 |
| APPL NO | 18/329459 |
| ART UNIT | 3798 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/0536 (20130101) A61B 8/00 (20130101) A61B 8/08 (20130101) A61B 8/485 (20130101) A61B 17/2258 (20130101) A61B 17/22004 (20130101) Original (OR) Class A61B 2017/00154 (20130101) A61B 2017/00172 (20130101) A61B 2017/00778 (20130101) A61B 2017/22001 (20130101) A61B 2017/22008 (20130101) A61B 2017/22088 (20130101) A61B 2017/22089 (20130101) A61B 2090/378 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0092 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150713 | Saeidi et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The Johns Hopkins University (Baltimore, Maryland); Children's National Medical Center (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); CHILDREN'S NATIONAL MEDICAL CENTER (Washington, District of Columbia) |
| INVENTOR(S) | Hamed Saeidi (College Park, Maryland); Axel Krieger (Alexandria, Virginia); Simon Leonard (State College, Pennsylvania); Justin Opfermann (Washington, District of Columbia); Michael Kam (Greenbelt, Maryland) |
| ABSTRACT | The present disclosure provides a system and method for controlling an articulating member including a tool. The system may include a dual camera system that captures near-infrared (NIR) images and point cloud images of a tissue or other substance that includes NIR markers. The system may generate a three-dimensional (3D) path based on identified positions of the NIR markers, may filter the generated path, and may generate a 3D trajectory for controlling the articulated arm of a robot having a tool to create an incision along the filtered path. In a shared control mode, an operator may generate manually control commands for the robot to guide the tool along such a path, while automated control commands are generated in parallel. One or more allocation functions may be calculated based on calculated manual and automated error models, and shared control signals may be generated based on the allocation functions. |
| FILED | Monday, November 16, 2020 |
| APPL NO | 17/098990 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/14 (20130101) A61B 18/16 (20130101) A61B 34/10 (20160201) Original (OR) Class A61B 34/25 (20160201) A61B 34/32 (20160201) A61B 34/76 (20160201) A61B 90/39 (20160201) A61B 2018/00595 (20130101) A61B 2034/107 (20160201) A61B 2090/371 (20160201) A61B 2090/3979 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150735 | Zharov |
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| FUNDED BY |
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| APPLICANT(S) | Bioventures, LLC (Little Rock, Arkansas) |
| ASSIGNEE(S) | Bioventures, LLC (Little Rock, Arkansas) |
| INVENTOR(S) | Vladimir Pavlovich Zharov (Little Rock, Arkansas) |
| ABSTRACT | A photoacoustic flow cytometry (PAFC) device for the in vivo detection of cells circulating in blood or lymphatic vessels is described. Ultrasound transducers attached to the skin of an organism detect the photoacoustic ultrasound waves emitted by target objects in response to their illumination by at least one pulse of laser energy delivered using at least one wavelength. The wavelengths of the laser light pulse may be varied to optimize the absorption of the laser energy by the target object. Target objects detected by the device may be unlabelled biological cells or cell products, contrast agents, or biological cells labeled with one or more contrast agents. |
| FILED | Thursday, February 10, 2022 |
| APPL NO | 17/668971 |
| ART UNIT | 3798 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0059 (20130101) A61B 5/0095 (20130101) Original (OR) Class A61B 5/412 (20130101) A61B 5/415 (20130101) A61B 5/416 (20130101) A61B 5/418 (20130101) A61B 5/02007 (20130101) A61B 5/7278 (20130101) A61B 8/08 (20130101) A61B 18/20 (20130101) A61B 2018/207 (20130101) A61B 2018/00642 (20130101) A61B 2018/20351 (20170501) A61B 2018/20357 (20170501) A61B 2018/20361 (20170501) Preparations for Medical, Dental, or Toilet Purposes A61K 49/22 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/147 (20130101) G01N 15/1425 (20130101) G01N 15/1434 (20130101) G01N 21/39 (20130101) G01N 21/1702 (20130101) G01N 2015/1477 (20130101) G01N 2201/0697 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150750 | Xu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland); Kennedy Krieger Institute (Baltimore, Maryland); City Iniversity of Hong Kong (Kowloon, China Hong Kong) |
| INVENTOR(S) | Jiadi Xu (Timonium, Maryland); Peter Van Zijl (Hanover, Maryland); Lin Chen (Baltimore, Maryland); Kannie Wai Yan Chan (Hong Kong, China PRC); Jianpan Huang (Hong Kong, China PRC) |
| ABSTRACT | A method of assessing the brain lymphatic or glymphatic system and the glucose transporter function on blood-cerebrospinal fluid barrier (BCSFB) of a subject using D-glucose or a D-glucose analog. A spatial map is generated of water MR signals that are sensitized to changes in D-glucose or a D-glucose analog in cerebrospinal fluid (CSF) of the subject. The spatial map is observed at one or more time points before, one or more time points during, and one or more time points after, raising the blood level of the D-glucose or a D-glucose analog in the subject CSF. A difference is detected between the MR signals of the spatial map before, during, and after raising the blood level of D-glucose or a D-glucose analog. A physiological parameter associated with the brain lymphatic or glymphatic system and the glucose transporter function on BCSFB of the subject is ascertained based on the detected difference. |
| FILED | Wednesday, April 07, 2021 |
| APPL NO | 17/918031 |
| ART UNIT | 3798 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/565 (20130101) G01R 33/4833 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150777 | Etkin et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Board of Regents, The University of Texas System (Austin, Texas); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Amit Etkin (Palo Alto, California); Yu Zhang (Palo Alto, California); Greg Fonzo (Palo Alto, California); Madhukar Trivedi (Palo Alto, California) |
| ABSTRACT | Provided herein are, inter alia, methods for identifying subjects suffering from depression that will respond to treatment with an antidepressant. |
| FILED | Friday, March 15, 2019 |
| APPL NO | 16/981822 |
| ART UNIT | 3798 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0075 (20130101) A61B 5/165 (20130101) A61B 5/316 (20210101) A61B 5/369 (20210101) A61B 5/4848 (20130101) Original (OR) Class A61B 5/7264 (20130101) A61B 5/7267 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/135 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/20 (20180101) G16H 20/70 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150813 | Pinton et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina) |
| INVENTOR(S) | Gianmarco Francesco Pinton (Chapel Hill, North Carolina); Thomas Montgomery Kierski (Durham, North Carolina); David Antonio Espindola Rojas (Chapel Hill, North Carolina); Paul Alexander Dayton (Carrboro, North Carolina); Isabel Grace Newsome (Chapel Hill, North Carolina) |
| ABSTRACT | A method for producing an image of a vessel with ultrasound includes administering a contrast agent particle into the vessel and delivering an ultrasound pulse having a first frequency range to the vessel. The method further includes detecting ultrasound energy scattered from the contrast agent particle at a second frequency range, converting the scattered ultrasound energy into an electronic radio frequency signal, and using an algorithm to determine a spatial location of the contrast agent particle based on extraction of a specific feature of the radio frequency signal. The method further includes generating an image by displaying a marker of the spatial location of the contrast agent particle with a resolution that is finer than a pulse length of the ultrasound pulse and repeating the steps for different contrast agent particles until sufficient markers have been accumulated to reconstruct a pattern of the vessel. |
| FILED | Monday, May 11, 2020 |
| APPL NO | 17/606986 |
| ART UNIT | 3798 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/481 (20130101) A61B 8/0891 (20130101) A61B 8/5207 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150931 | Johnson |
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| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Bankole A. Johnson (Charlottesville, Virginia) |
| ABSTRACT | Compositions and methods are provided that are useful for diagnosing, treating, and monitoring alcohol dependence and disorders, susceptibility to alcohol dependence disorders, as well as drug related dependence and disorders. The methods include treating patients with an antagonist of the serotonin receptor 5-HT3 for such disorders, wherein the patient's serotonin transporter gene SLC6A4 is known to have particular genotypes. |
| FILED | Monday, April 18, 2022 |
| APPL NO | 17/659641 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4178 (20130101) Original (OR) Class A61K 31/7048 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6888 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150948 | Bazin-Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | INIMMUNE CORPORATION (Missoula, Montana) |
| ASSIGNEE(S) | National Institutes of Health (NIH), U.S. Dept. of Health and Human Services (DHHS), U.S. Government (Bethesda, Maryland) |
| INVENTOR(S) | Helene Bazin-Lee (Stevensville, Montana); George Ettenger (Missoula, Montana); Juhienah Khalaf (Hamilton, Montana); Kendal T. Ryter (Hamilton, Montana) |
| ABSTRACT | Toll-like receptor (TLR) ligands having an allose-based core are stable in aqueous formulation and are useful in treating, preventing, or reducing susceptibility to diseases or conditions mediated by TLRs, such as cancer, infectious disease, allergy, autoimmune disease, sepsis, and ischemia reperfusion. |
| FILED | Monday, August 29, 2022 |
| APPL NO | 17/898165 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7008 (20130101) Original (OR) Class A61K 39/35 (20130101) A61K 39/39 (20130101) A61K 45/06 (20130101) A61K 2039/57 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) A61P 11/02 (20180101) A61P 17/04 (20180101) A61P 31/04 (20180101) A61P 35/00 (20180101) A61P 37/00 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/12 (20130101) C07H 15/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150950 | Imai et al. |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Shin-Ichiro Imai (St. Louis, Missouri); Rajendra Apte (Clayton, Missouri) |
| ABSTRACT | Disclosed are methods and compositions related to methods of treating, ameliorating, mitigating, slowing, arresting, preventing or reversing various diseases and conditions, including age-related obesity, age-related increases in blood lipid levels, age-related decreases in insulin sensitivity, age-related decreases in memory function, and age-related changes in eye function such as macular degeneration. The methods comprise administering nicotinamide mononucleotide (NMN) to a subject. In some embodiments, the administration can be oral administration. Also disclosed are pharmaceutical compositions comprising NMN. |
| FILED | Thursday, September 21, 2023 |
| APPL NO | 18/471764 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0048 (20130101) A61K 9/0053 (20130101) A61K 31/455 (20130101) A61K 31/706 (20130101) Original (OR) Class A61K 31/7064 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150969 | Li et al. |
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| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Song Li (Wexford, Pennsylvania); Stephen Howard Thorne (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method of modifying a virus for in vivo delivery to a region of interest includes forming an enveloping composition including a lipid conjugate formed by conjugating at least one lipid with at least one hydrophilic compound via a linkage which is cleavable under conditions present in the region of interest and combining the virus with the enveloping composition to encompass the virus within the enveloping structure. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 16/088228 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1271 (20130101) A61K 35/76 (20130101) Original (OR) Class A61K 47/10 (20130101) A61K 47/24 (20130101) A61K 47/28 (20130101) A61K 47/34 (20130101) A61K 47/6911 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150973 | Tantin |
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| FUNDED BY |
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| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Dean Tantin (Salt Lake City, Utah) |
| ABSTRACT | Disclosed herein, are compounds comprising a peptide, wherein the peptide is OCA-B or an OCA-B fragment thereof; a linker; and a cell penetrating peptide. Also described herein, are methods of administering compounds to subjects for the treatment of Type I diabetes and blocking the interaction between OCA-B and Jmjd1a. |
| FILED | Wednesday, April 17, 2019 |
| APPL NO | 17/051341 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/08 (20130101) A61K 38/16 (20130101) Original (OR) Class A61K 47/645 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150986 | Jacobs, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York) |
| ASSIGNEE(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE (Bronx, New York) |
| INVENTOR(S) | William Jacobs, Jr. (Pelham, New York); Betsy Herold (Rowayton, Connecticut); Joseph Dardick (Bronx, New York); Kayla A. Weiss (Bronx, New York) |
| ABSTRACT | Recombinant herpes simplex virus 2 (HSV-2) vaccine vectors, compositions and vaccines comprising such, and methods of use thereof are each provided. |
| FILED | Tuesday, November 29, 2022 |
| APPL NO | 18/071109 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/245 (20130101) Original (OR) Class Peptides C07K 1/13 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/102 (20130101) C12N 2710/16034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150987 | Diamond et al. |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Don J. Diamond (Glendora, California); Felix Wussow (Duarte, California) |
| ABSTRACT | In one embodiment, an expression system for expressing a UL128 complex is provided herein. The expression system may include a bacterial artificial chromosome (BAC) construct, wherein the BAC construct comprises a viral vector inserted with a set of DNA sequences that encode a UL128 complex. In another embodiment, a vaccine composition for preventing HCMV infection is provided. The vaccine composition may include a viral or bacterial vector capable of expressing a UL128 complex and a pharmaceutically acceptable carrier, adjuvant, additive or combination thereof or additional vector expressing a protein adjuvant. The viral vector may be an MVA and the UL128 complex includes five HCMV proteins or antigenic fragments thereof: UL128, UL130, UL131A, gL, and gH. In some embodiments, the viral vector is further inserted with one or more additional DNA sequences that encode one or more additional HCMVHCMV proteins or antigenic fragments thereof such as pp65, gB or both, or such as gM/gN or gO. |
| FILED | Tuesday, June 13, 2023 |
| APPL NO | 18/334279 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/5254 (20130101) A61K 2039/5256 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/16122 (20130101) C12N 2710/16134 (20130101) C12N 2710/24143 (20130101) C12N 2799/023 (20130101) C12N 2800/204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151000 | Green et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Jordan J. Green (Baltimore, Maryland); Stephany Yi Tzeng (Baltimore, Maryland); Kelly Rhodes (Baltimore, Maryland); Giorgio Raimondi (Baltimore, Maryland); Marcos Iglesias Lozano (Baltimore, Maryland); Jamie Spangler (Baltimore, Maryland); Jakub Tomala (Baltimore, Maryland); Derek VanDyke (Baltimore, Maryland); Randall A. Meyer (Baltimore, Maryland) |
| ABSTRACT | The disclosure is directed to a biodegradable particle comprising a polyester or polyester blend, a first protein that binds to an immune cell, and a second protein that promotes proliferation and/or activation of immune cells, and a third soluble protein or small molecule encapsulated within the particle. The second protein is a fusion protein comprising at least a portion of an antibody and at least a portion of a cytokine (i.e., an immunocytokine). The disclosure also is directed to methods for treating a disease or condition in a subject (e.g., an autoimmune disease) comprising administering the aforementioned biodegradable particle to the subject. |
| FILED | Monday, April 13, 2020 |
| APPL NO | 17/602856 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) A61K 31/436 (20130101) A61K 47/62 (20170801) A61K 47/6813 (20170801) A61K 47/6845 (20170801) A61K 47/6849 (20170801) A61K 47/6937 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151047 | Alsberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Eben Alsberg (Cleveland, Ohio); Oju Jeon (Cleveland, Ohio); Jung-Youn Shin (Cleveland, Ohio); Robyn Marks (Cleveland, Ohio); Mitchell Hopkins (Cleveland, Ohio); Hongyun Park (Cleveland, Ohio) |
| ABSTRACT | A composition includes a hydrogel that includes a plurality biodegradable natural polymer macromers crosslinked with a first agent and optionally a plurality of cells dispersed in the crosslinked macromers, the microgels are capable of being crosslinked with a second agent that is different than the first crosslinking agent. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/641056 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/26 (20130101) A61L 27/44 (20130101) Original (OR) Class A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 27/3608 (20130101) A61L 27/3834 (20130101) A61L 2300/236 (20130101) A61L 2300/252 (20130101) A61L 2300/412 (20130101) A61L 2300/414 (20130101) A61L 2400/16 (20130101) A61L 2430/40 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0084 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/002 (20130101) Derivatives of Natural Macromolecular Compounds C08H 1/06 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/04 (20130101) C08L 5/08 (20130101) C08L 89/06 (20130101) C08L 89/06 (20130101) C08L 89/06 (20130101) C08L 89/06 (20130101) C08L 2205/04 (20130101) C08L 2312/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151074 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Yong Wang (State College, Pennsylvania); James Coyne (State College, Pennsylvania); David Kauffman (Ambler, Pennsylvania); Brandon Davis (Yardley, Pennsylvania) |
| ABSTRACT | A method of providing therapeutic treatment by delivering therapeutic aptamers locally to a target site using microneedles includes providing complementary sequence modified microneedles by reacting a complementary sequence (CS) with a polymer thereby forming a covalent bond between the polymer and the CS, forming microneedle patches using an initial casting solution consisting of the polymer, the therapeutic aptamer, and a covalent bond between a complementary sequence (CS) and the polymer, thereby loading the therapeutic aptamer into the microneedles, each microneedle having a base, shaft and tip, physically binding the therapeutic aptamer to the CS, inserting the microneedles into the tissue such that the tips and shafts are embedded into the target site and the bases are on a surface of the target site, and sustained release of the aptamer to the target site due to dissociation of the aptamer from the CS over time. |
| FILED | Tuesday, August 27, 2019 |
| APPL NO | 17/271486 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) A61K 38/1866 (20130101) A61K 47/32 (20130101) A61K 47/61 (20170801) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0023 (20130101) A61M 2037/0046 (20130101) A61M 2037/0053 (20130101) A61M 2037/0061 (20130101) A61M 2202/0445 (20130101) A61M 2210/04 (20130101) A61M 2210/125 (20130101) A61M 2210/0612 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151103 | Shah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Nishal Pradeepkumar Shah (Stanford, California); Eduardo Jose Chichilnisky (Stanford, California) |
| ABSTRACT | Systems and methods for artificial sight in accordance with embodiments of the invention are illustrated. One embodiment includes a retinal prosthesis system including an external controller, a scene imager, an eye imager, an implanted controller, and a stimulation interface in communication with the implanted controller, where the stimulation interface is positioned to stimulate a plurality of retinal ganglion cells (RGCs) of the eye, where the external controller is configured to obtain image data describing a scene from the scene imager, obtain eye position data from the eye imager, determine a field of view (FOV) in the scene based on the eye position data; where the implanted controller is configured to obtain the FOV from the external controller, continuously select stimulation pulses from a dictionary based on the FOV, and stimulate the plurality of RGCs using the stimulation interface in accordance with the selected stimulation pulses. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/441261 |
| ART UNIT | 3796 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) A61N 1/025 (20130101) A61N 1/0543 (20130101) A61N 1/36046 (20130101) Original (OR) Class A61N 1/37235 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151245 | Paulovich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Amanda G. Paulovich (Seattle, Washington); Richard Ivey (Federal Way, Washington); Jacob Kennedy (Seattle, Washington); Travis Lorentzen (Bothell, Washington); Amanda Woodcock (Seattle, Washington); Scott C. Thielman (Seattle, Washington); Elijah E. Hooper (Seattle, Washington) |
| ABSTRACT | Devices and methods for bio-specimen refrigeration are provided. In an embodiment, the bio-specimen refrigeration devices of the present disclosure include a housing having a lid and a base portion, wherein the lid is selectively moveable between an open position and a closed position; a coolant cartridge chamber disposed in the housing and configured to fluidically couple with a coolant cartridge disposed in the coolant cartridge chamber; and a cooling chamber disposed in the housing and configured to receive a fluid coolant from the coolant cartridge, wherein in the closed position, the lid seals the cooling chamber. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/531260 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 7/00 (20130101) Original (OR) Class B01L 2200/04 (20130101) B01L 2200/0689 (20130101) B01L 2300/1894 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152007 | Schiltz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Gary E. Schiltz (Naperville, Illinois); Rama K. Mishra (Chicago, Illinois); Huiying Han (Chicago, Illinois); Sarki A. Abdulkadir (Lombard, Illinois); Javier Izquierdo-Ferrer (Chicago, Illinois); Atul D. Jain (Chicago, Illinois) |
| ABSTRACT | Disclosed are substituted heterocycle compounds including substituted pyrazoles, substituted pyrimidines, and substitute triazoles. The substituted heterocycles disclosed herein are shown to be useful in inhibiting c-MYC and may be utilized as therapeutics for treating cancer and cell proliferative disorders. |
| FILED | Friday, August 31, 2018 |
| APPL NO | 17/272346 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 231/06 (20130101) C07D 231/12 (20130101) C07D 231/20 (20130101) Original (OR) Class C07D 239/26 (20130101) C07D 239/42 (20130101) C07D 249/06 (20130101) C07D 261/08 (20130101) C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/04 (20130101) C07D 403/12 (20130101) C07D 405/04 (20130101) C07D 405/10 (20130101) C07D 405/12 (20130101) C07D 409/10 (20130101) C07D 498/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152008 | Raghavan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Srivatsan Raghavan (Boston, Massachusetts); Bruce Kuan-Yee Hua (Cambridge, Massachusetts); Shubhroz Gill (Cambridge, Massachusetts); Stuart Schreiber (Cambridge, Massachusetts); William Hahn (Boston, Massachusetts); Paul Clemons (Cambridge, Massachusetts); Raymond Ng (Boston, Massachusetts); Partha Nag (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are compounds useful for the treatment of various proliferative diseases. These compounds, as well as pharmaceutically acceptable salts thereof may be formulated in pharmaceutical compositions, and may be used in methods of treatment and/or prophylaxis of proliferative diseases, including cancer, and more specifically, pancreatic cancer. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/013269 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0043 (20130101) A61K 9/0053 (20130101) Heterocyclic Compounds C07D 233/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152036 | Salvino et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Joseph M. Salvino (Chester Springs, Pennsylvania); Xin Feng (ChongQing, China PRC); Alessandro Fatatis (Penn Valley, Pennsylvania); Fei Shen (Philadelphia, Pennsylvania); Olimpia Meucci (Penn Valley, Pennsylvania) |
| ABSTRACT | The disclosure provides compounds of formula (II) having the structure: Compounds of formula (II) are fractalkine receptor agonists and useful in treating, preventing or minimizing metastasis in a subject diagnosed with cancer. The compounds of the disclosure are further useful in treating central nervous system diseases (such as, but not limited to, HIV Associated Neurocognitive Disorders (HAND), and/or Alzheimer's disease), pain, inflammation (such as, but not limited to, arthritis), cardiovascular disease (such as, but not limited to, undesired vascular smooth muscle proliferation, atherosclerosis, coronary vascular endothelial dysfunction, and/or coronary artery disease), and/or multiple sclerosis. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/583554 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/704 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152053 | Boons et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (Athens, Georgia) |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia) |
| INVENTOR(S) | Geert-Jan Boons (Athens, Georgia); Anthony Robert Prudden (Athens, Georgia); Lin Liu (Athens, Georgia) |
| ABSTRACT | Disclosed herein are oligosaccharides and intermediates useful for the production thereof. The compounds are useful as analytical standards and as intermediates for the preparation of more complex oligosaccharide and N-glycan products. The compounds may be prepared in high purity using the selective stop/go synthetic methods disclosed herein. |
| FILED | Thursday, August 31, 2023 |
| APPL NO | 18/240621 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 5/06 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/26 (20130101) C12P 19/305 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152080 | Scadden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts); The Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | David T. Scadden (Weston, Massachusetts); Rahul Palchaudhuri (Cambridge, Massachusetts); Derrick J. Rossi (Newton, Massachusetts); Agnieszka D. Czechowicz (Boston, Massachusetts) |
| ABSTRACT | Disclosed herein are non-myeloablative antibody-toxin conjugates and compositions that target cell surface markers, such as the CD34, CD45 or CD117 receptors, and related methods of their use to effectively conditioning a subject's tissues (e.g., bone marrow tissue) prior to engraftment or transplant. The compositions and methods disclosed herein may be used to condition a subject's tissues in advance of, for example, hematopoietic stem cell transplant and advantageously such compositions and methods do not cause the toxicities that are commonly associated with traditional conditioning methods. |
| FILED | Tuesday, December 29, 2020 |
| APPL NO | 17/137337 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 38/164 (20130101) A61K 38/168 (20130101) A61K 47/6825 (20170801) A61K 47/6849 (20170801) A61K 47/6898 (20170801) Peptides C07K 4/04 (20130101) C07K 16/289 (20130101) C07K 16/2866 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) G01N 33/56966 (20130101) G01N 33/57407 (20130101) G01N 33/57434 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152085 | Desir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Gary Desir (Woodbridge, Connecticut); Abigail Hunt (Alameda, California); Jessica O-Rear (Redwood City, California); Peter Flynn (San Francisco, California) |
| ABSTRACT | The invention provides compositions and methods for binding and inhibiting renalase. In one embodiment, the renalase binding molecule inhibits renalase activity. Thus, in diseases and conditions where a reduction of renalase activity is beneficial, such inhibitory renalase binding molecules act as therapeutics. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/739691 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/40 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2317/51 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/515 (20130101) C07K 2317/565 (20130101) Enzymes C12Y 106/03 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) G01N 2333/90209 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152089 | Ndinguri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eastern Kentucky University (Richmond, Kentucky) |
| ASSIGNEE(S) | Eastern Kentucky University (Richmond, Kentucky) |
| INVENTOR(S) | Margaret Ndinguri (Richmond, Kentucky); Lindsay Cormier (Richmond, Kentucky) |
| ABSTRACT | The conjugation of luteinizing hormone-releasing hormone (LHRH) with activated cisplatin using a malonate linker gives rise to a new Platinum-LHRH conjugate that effectively targets tumor cells that express the LHRH receptor. The Pt-LHRH conjugate may be used in a method for killing or inhibiting the growth of a tumor cell, especially in late state, highly invasive and aggressive stage IV tumors and in reoccurring tumors. |
| FILED | Friday, November 19, 2021 |
| APPL NO | 17/531246 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/243 (20190101) A61K 47/64 (20170801) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0093 (20130101) Peptides C07K 7/23 (20130101) Original (OR) Class C07K 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152241 | Ting et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Aalborg University (Aalborg, Denmark) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Aalborg University (Aalborg, Denmark) |
| INVENTOR(S) | David T. Ting (Dover, Massachusetts); Daniel A. Haber (Chestnut Hill, Massachusetts); Shyamala Maheswaran (Lexington, Massachusetts); Francesca Bersani (Turin, Italy); Anders M. Naar (Arlington, Massachusetts); Mihir Shivadatta Rajurkar (Worcester, Massachusetts); Sakari Kauppinen (Holte, Denmark); Andreas Petri (Frederiksberg, Denmark) |
| ABSTRACT | Methods for treating cancer, e.g., cancer of epithelial origin, by specifically targeting human satellite II (HSATII) using sequence specific agents such as oligonucleotides. |
| FILED | Wednesday, April 24, 2019 |
| APPL NO | 16/393557 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/341 (20130101) C12N 2310/3231 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152242 | Duan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri); THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (Rockville, Maryland) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri); The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | Dongsheng Duan (Columbia, Missouri); Chady Hakim (Columbia, Missouri); Nalinda B. Wasala (Columbia, Missouri); Yongping Yue (Columbia, Missouri) |
| ABSTRACT | Disclosed herein are methods for systemically editing a gene in a subject and for systemically treating a genetic condition in a subject using a dual-vector CRISPR-Cas therapy. The methods comprise administering to the subject, via systemic administration, a gene editing AAV vector encoding a CRISPR effector protein (e.g., a Cas protein) and a targeting AAV vector providing one or more gRNAs targeted to the gene. In the methods, the ratio of the targeting AAV vector to the gene editing vector is greater than or equal to 2. Also provided are dual-vector systems for editing a gene or treating a genetic disease in a subject. |
| FILED | Tuesday, April 23, 2019 |
| APPL NO | 17/049980 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/86 (20130101) C12N 15/102 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2320/32 (20130101) C12N 2750/14141 (20130101) C12N 2830/008 (20130101) C12N 2830/50 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152250 | Shi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DIAGNOLOGIX, LLC (San Diego, California) |
| ASSIGNEE(S) | DIAGNOLOGIX, LLC (San Diego, California) |
| INVENTOR(S) | Guixin Shi (San Diego, California); Kimberly Liu (San Diego, California); Ying-Ting Wang (San Diego, California) |
| ABSTRACT | A method for activating and expanding isolated T cells, the method including adding to isolated T cells ligands presenting microbubbles having a flexible lipid shell with an inner bubble wall enclosing a gas and an outer bubble wall conjugated to ligands capable of achieving cell contact dependent juxtacrine signaling on the isolated T cells; and adding to isolated T cells ligands presenting microbubbles having a flexible lipid shell with an inner bubble wall enclosing a gas and an outer bubble wall conjugated to an antigen capable of forming an immunological synapse (IS) with the T cells. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/583264 |
| ART UNIT | 1677 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 47/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0081 (20130101) C12N 5/0087 (20130101) C12N 5/0093 (20130101) C12N 5/0636 (20130101) Original (OR) Class C12N 2501/50 (20130101) C12N 2501/515 (20130101) C12N 2501/599 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/536 (20130101) G01N 33/538 (20130101) G01N 33/544 (20130101) G01N 33/5432 (20130101) G01N 33/56972 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152253 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Sungjin Kim (Davis, California); Jeannine Scott (Charlotte, Michigan) |
| ABSTRACT | The invention relates to a specialized subpopulation of natural killer cells that have enhanced effector functions and the potential to kill malignant tumor cells or infected cells when the natural killer cells are exposed to an antibody bound to the tumor cells or the infected cells. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/044866 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0646 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152254 | Joung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Morgan Maeder (Brookline, Massachusetts); James Angstman (Charlestown, Massachusetts) |
| ABSTRACT | Fusion proteins comprising a DNA binding domain, e.g., a TAL effector repeat array or zinc finger, and a catalytic domain comprising a sequence that catalyzes hydroxylation of methylated cytosines in DNA, and methods of use thereof. |
| FILED | Thursday, January 14, 2021 |
| APPL NO | 17/149458 |
| ART UNIT | 1699 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 2319/80 (20130101) C07K 2319/81 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0071 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152910 | Evke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Erin Evke (Ann Arbor, Michigan); Eugene Shteyn (Ann Arbor, Michigan); Max Shtein (Ann Arbor, Michigan) |
| ABSTRACT | A sensor device includes a substrate having a plurality of cuts through the substrate to define a set of substrate sections, the substrate being flexible, and a plurality of sensor structures supported by the substrate, each sensor structure of the plurality of sensor structures being disposed at a respective substrate section of the set of substrate sections. Deformation of the substrate deforms each respective substrate section of the set of substrate sections such that each respective substrate section is deformed to a respective extent. Each sensor structure of the plurality of sensor structures is configured to provide an indication of the respective extent of the deformation. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 17/294172 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 11/30 (20130101) Original (OR) Class Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152970 | Colburn Hildebrand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David Grant Colburn Hildebrand (Cambridge, Massachusetts); Brett Jesse Graham (Cambridge, Massachusetts); Wei-Chung Allen Lee (Cambridge, Massachusetts) |
| ABSTRACT | A tape for collecting tissue samples in a manner compatible with imaging in a transmission electron microscopy (TEM) system, includes a tape substrate having two side walls forming a trough. The trough is defined by a bottom surface of the tape substrate and internal surfaces of the side walls, with an open side therebetween. A support film is attached to a top surface of the tape substrate, and a plurality of apertures is spaced at predetermined locations along the length of the tape substrate, each aperture being covered by the support film. The tape includes a stacked configuration in which the tape substrate is wound in layers, the bottom surfaces of the side walls in one layer being in contact with the support film in an immediately adjacent layer. The apertures in the second layer are aligned within the trough of the first layer, between the side walls. |
| FILED | Thursday, January 27, 2022 |
| APPL NO | 17/586727 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/36 (20130101) Original (OR) Class G01N 35/00009 (20130101) G01N 2001/362 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152990 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Ji-Xin Cheng (Newton, Massachusetts); Yi Zhang (Boston, Massachusetts); Cheng Zong (Boston, Massachusetts) |
| ABSTRACT | Microscopic analysis of a sample includes a fluorescent dye disposed within the sample. A mid-IR optical source generates a mid-infrared beam, which is directed onto the sample to induce a temperature change by absorption of the mid-infrared beam. An optical source generates a probe beam directed to impinge on the sample. A detector detects fluorescent emissions from the sample when the probe beam impinges on the sample. A data acquisition and processing system acquires and processes the detected fluorescent emissions from the sample to: (i) generate a signal indicative of infrared absorption by the sample, (ii) generate a signal indicative of temperature in the sample based on the signal indicative of infrared absorption by the sample, (iii) generate an image of the sample using the signal indicative of temperature in the sample. |
| FILED | Tuesday, December 13, 2022 |
| APPL NO | 18/080481 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6458 (20130101) Original (OR) Class G01N 33/5044 (20130101) G01N 2021/655 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152991 | Butte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| ASSIGNEE(S) | Cedars-Sinai Medical Center (Los Angeles, California) |
| INVENTOR(S) | Pramod Butte (Studio City, California); Paul Lapchak (San Diego, California); David Scott Kittle (Running Springs, California) |
| ABSTRACT | The invention provides systems for characterizing a biological sample by analyzing emission of fluorescent light from the biological sample upon excitation and methods for using the same. The system includes a laser source, collection fibers, a demultiplexer and an optical delay device. All references cited herein are incorporated by reference in their entirety as though fully set forth. Unless defined otherwise, technical and scientific terms used herein have the same meaning as commonly understood by one of-ordinary skill in the art in which this invention belongs. |
| FILED | Thursday, July 21, 2022 |
| APPL NO | 17/870090 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) A61B 5/0084 (20130101) A61B 5/1459 (20130101) A61B 5/4866 (20130101) A61B 5/14556 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0218 (20130101) G01J 3/2889 (20130101) G01J 3/4406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) G01N 21/645 (20130101) G01N 21/6402 (20130101) G01N 21/6408 (20130101) G01N 21/6428 (20130101) G01N 21/6486 (20130101) Original (OR) Class G01N 2021/6417 (20130101) G01N 2021/6421 (20130101) G01N 2021/6484 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153056 | Unanue et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emil R. Unanue (St. Louis, Missouri); Xiaoxiao Wan (St. Louis, Missouri); Cheryl Lichti (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Emil R. Unanue (St. Louis, Missouri); Xiaoxiao Wan (St. Louis, Missouri); Cheryl Lichti (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of compositions for and methods of diagnosing, prognosing, and treating diabetes. |
| FILED | Wednesday, July 15, 2020 |
| APPL NO | 16/929411 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/26 (20130101) C07K 2317/76 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/74 (20130101) Original (OR) Class G01N 33/505 (20130101) G01N 33/6848 (20130101) G01N 2333/62 (20130101) G01N 2800/042 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153110 | Emir et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Uzay Emir (West Lafayette, Indiana); Mark Chiew (West Lafayette, Indiana) |
| ABSTRACT | A method of performing magnetic resonance spectroscopic imaging (MRSI) includes transmitting a multi-slice excitation pulse through tissue, the multi-slice excitation pulse configured to generate multi-slice MRSI signals. The method also includes performing density weighted concentric ring acquisition on the multi-slice MRSI signals. The method further includes receiving the generated multi-slice MRSI signals in a plurality of sensors disposed in various locations around the tissue. Imaging data is reconstructed based on the acquired imaging signals. A representation of the data is displayed. |
| FILED | Tuesday, November 28, 2023 |
| APPL NO | 18/521825 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/485 (20130101) G01R 33/4824 (20130101) G01R 33/4828 (20130101) G01R 33/4835 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153111 | Vasanawala et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Shreyas S. Vasanawala (Stanford, California); Yan Wu (Mountain View, California) |
| ABSTRACT | A method for magnetic resonance imaging performs chemical shift encoded imaging to produce complex dual-echo images which are then applied (with imaging parameters) as input to a deep neural network to produce as output water-only and fat-only images. The deep neural network can be trained with ground truth water/fat images derived from chemical shift encoded images using a conventional water-fat separation algorithm such as projected power approach, IDEAL, or VARPRO. The chemical shift encoded imaging comprises performing an image acquisition with the MRI scanner via a spoiled-gradient echo sequence or a spin-echo sequence. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/102249 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/485 (20130101) Original (OR) Class G01R 33/4828 (20130101) Image Data Processing or Generation, in General G06T 11/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153130 | Parker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Kevin J. Parker (Rochester, New York); Jihye Baek (Rochester, New York) |
| ABSTRACT | A method of forming an image of a region of interest using a pulse-echo imaging device is described. The method includes the steps of generating a pulse using the pulse-echo imaging device, causing the pulse to be incident on the region of interest to generate a reflected echo, receiving the reflected echo in the pulse-echo imaging device, comparing a measure of frequency content of the reflected echo to the transmitted pulse, and frequency shifted replicas of the transmitted pulse, wherein each is associated with a unique label, selecting a label based on the comparison, and generating an image incorporating the selected label. |
| FILED | Tuesday, January 14, 2020 |
| APPL NO | 16/742084 |
| ART UNIT | 3797 — Printing/Measuring and Testing |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/52071 (20130101) G01S 15/8977 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 11/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154322 | Adjouadi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Malek Adjouadi (Miami, Florida); Mohammad Eslami (Miami, Florida); Solale Tabarestani (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board Of Trustees (Miami, Florida) |
| INVENTOR(S) | Malek Adjouadi (Miami, Florida); Mohammad Eslami (Miami, Florida); Solale Tabarestani (Miami, Florida) |
| ABSTRACT | Systems and methods are provided for color-coded visualization to aid in diagnosis and prognosis of Alzheimer's disease (AD). The color-coded visualization mechanism can be driven by an integrated machine learning (ML) model, which can take as its inputs neuroimaging (e.g., magnetic resonance imaging (MRI), positron emission tomography (PET)) data, neuropsychological test scores, the cerebrospinal fluid (CSF) biomarker, and/or risk factors. With these inputs, the ML model can generate a color-coded visualization of the disease state. |
| FILED | Tuesday, March 12, 2024 |
| APPL NO | 18/602673 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4088 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) G06T 11/001 (20130101) G06T 2207/10024 (20130101) G06T 2207/10088 (20130101) G06T 2207/10104 (20130101) G06T 2207/30016 (20130101) G06T 2207/30204 (20130101) Image or Video Recognition or Understanding G06V 10/811 (20220101) Original (OR) Class G06V 10/7715 (20220101) G06V 2201/03 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154677 | Anticevic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Alan Anticevic (New Haven, Connecticut); John Murray (New Haven, Connecticut); Jie Lisa Ji (New Haven, Connecticut) |
| ABSTRACT | Described herein are example methods and systems for neuro-behavioral relationships in dimensional geometric bedding (N-BRIDGE), which includes a comprehensive, data-driven analytic framework for mapping the multi-dimensional relationships between neural and behavioral features in humans N-BRIDGE allows mapping of variations along newly-defined data-driven behavioral dimensions that capture the geometry of behavioral/symptom variation to variation in specific neural features. A method for treating a patient based on neuro-behavioral mapping includes receiving, from a user interface of a computing device, behavioral data of a patient corresponding to mental health or cognitive status of the patient, predicting, by at least one processor of the computing device, a neural feature map for the patient representative of neural data based on the behavioral data, determining, by the at least one processor, a therapeutic associated with the neural feature map, and treating the patient with the therapeutic associated with the neural feature map. |
| FILED | Wednesday, March 13, 2019 |
| APPL NO | 16/980136 |
| ART UNIT | 3686 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/165 (20130101) A61B 5/7264 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/70 (20180101) Original (OR) Class G16H 40/63 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155519 | Walk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); MOXZ GmbH (Berlin, Germany) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); MOXZ GmbH (Berlin, Germany) |
| INVENTOR(S) | Philipp Walk (Pasadena, California); Babak Hassibi (San Marino, California); Peter Jung (Berlin, Germany) |
| ABSTRACT | Systems and methods for transmitting data using various Modulation on Zeros schemes are described. In many embodiments, a communication system is utilized that includes a transmitter having a modulator that modulates a plurality of information bits to encode the bits in the zeros of the z-transform of a discrete-time baseband signal. In addition, the communication system includes a receiver having a decoder configured to decode a plurality of bits of information from the samples of a received signal by: determining a plurality of zeros of a z-transform of a received discrete-time baseband signal based upon samples from a received continuous-time signal, identifying zeros that encode the plurality of information bits, and outputting a plurality of decoded information bits based upon the identified zeros. |
| FILED | Friday, July 21, 2023 |
| APPL NO | 18/357064 |
| ART UNIT | 2635 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Multiplex Communication H04J 11/00 (20130101) H04J 2011/0096 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0204 (20130101) H04L 27/2627 (20130101) Original (OR) Class H04L 27/2639 (20130101) H04L 27/2663 (20130101) H04L 27/26532 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12150497 | Redmond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vorbeck Materials Corp. (Jessup, Maryland) |
| ASSIGNEE(S) | Vorbeck Materials Corp. (Jessup, Maryland) |
| INVENTOR(S) | Kate Redmond (Baltimore, Maryland); Dan Scheffer (Frederick, Maryland); Sriram Manivannan (Baltimore, Maryland); Keren Espina (Randallstown, Maryland); Ethan Traub (Jessup, Maryland); Jodie Kuo (Jessup, Maryland); John S Lettow (Washington, District of Columbia) |
| ABSTRACT | The present invention relates generally to transmission lines and specifically to textile transmission line assemblies. The textile transmission line assemblies are capable of lateral bending, axial rotation, and stretching without suffering from a statistically significant loss of its performance characteristics. Antenna elements are incorporated with the textile transmission line assemblies (hereinafter “combination assemblies”). The textile transmission line assemblies can be incorporated in to garments, apparel items, bags, tents, or other textile-based objects. The textile transmission line assemblies are configured to be flexibly affixed to textile items. The textile transmission line assemblies are impact resistant. Wearable communications systems that incorporate at least one textile transmission line assembly and/or combination assembly are also disclosed. |
| FILED | Wednesday, February 23, 2022 |
| APPL NO | 17/679070 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/002 (20130101) Original (OR) Class Antennas, i.e Radio Aerials H01Q 1/273 (20130101) Transmission H04B 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12150655 | Brody et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland); The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland); The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | David L. Brody (Bethesda, Maryland); David Blodgett (Ellicott City, Maryland); Adam Cohen (Baltimore, Maryland); Max R. Basescu (Baltimore, Maryland); Kevin C. Wolfe (Lutherville, Maryland); Jared M. Wormley (Silver Spring, Maryland) |
| ABSTRACT | An intracranial access device includes a housing having an operator-facing side and a patient-facing side and an opening therethrough extending from the operator-facing side to the patient-facing side. The device further includes at least one fastener configured to secure the device to a cranium of a patient. The device further includes a drill mounted to a surface of the housing and a cauterizer. The device may further include a number of sensors arranged on the patient-facing side of the housing and configured to identify a hemorrhage location. |
| FILED | Thursday, July 16, 2020 |
| APPL NO | 17/627567 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/031 (20130101) A61B 17/1695 (20130101) Original (OR) Class A61B 17/1739 (20130101) A61B 18/1402 (20130101) A61B 90/11 (20160201) A61B 2018/00321 (20130101) A61B 2018/00565 (20130101) A61B 2018/00595 (20130101) A61B 2018/00791 (20130101) A61B 2090/033 (20160201) A61B 2090/064 (20160201) A61B 2090/103 (20160201) A61B 2090/374 (20160201) A61B 2090/3762 (20160201) A61B 2217/005 (20130101) A61B 2218/007 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0539 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151000 | Green et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Jordan J. Green (Baltimore, Maryland); Stephany Yi Tzeng (Baltimore, Maryland); Kelly Rhodes (Baltimore, Maryland); Giorgio Raimondi (Baltimore, Maryland); Marcos Iglesias Lozano (Baltimore, Maryland); Jamie Spangler (Baltimore, Maryland); Jakub Tomala (Baltimore, Maryland); Derek VanDyke (Baltimore, Maryland); Randall A. Meyer (Baltimore, Maryland) |
| ABSTRACT | The disclosure is directed to a biodegradable particle comprising a polyester or polyester blend, a first protein that binds to an immune cell, and a second protein that promotes proliferation and/or activation of immune cells, and a third soluble protein or small molecule encapsulated within the particle. The second protein is a fusion protein comprising at least a portion of an antibody and at least a portion of a cytokine (i.e., an immunocytokine). The disclosure also is directed to methods for treating a disease or condition in a subject (e.g., an autoimmune disease) comprising administering the aforementioned biodegradable particle to the subject. |
| FILED | Monday, April 13, 2020 |
| APPL NO | 17/602856 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) A61K 31/436 (20130101) A61K 47/62 (20170801) A61K 47/6813 (20170801) A61K 47/6845 (20170801) A61K 47/6849 (20170801) A61K 47/6937 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151789 | Seeley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| INVENTOR(S) | Eric Seeley (Seebeck, Washington); Jacob Snow (Bremerton, Washington) |
| ABSTRACT | A system for joining counter-rotating propeller assemblies comprising modular elements and attachable components, including a male end adapted to join a single-piece female end by rotating the male end into the single-piece female end such that data bus terminals align and power bus terminals align. The system can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed systems for each mission. The joints connecting the modules are designed such that power and data connections between modules are reliably made. |
| FILED | Wednesday, July 19, 2023 |
| APPL NO | 18/224021 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/04 (20130101) Original (OR) Class B63G 2008/002 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/91 (20130101) H01R 12/7005 (20130101) H01R 13/64 (20130101) H01R 13/641 (20130101) H01R 13/6205 (20130101) H01R 13/7175 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151790 | Seeley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| INVENTOR(S) | Eric Seeley (Seebeck, Washington); Jacob Snow (Bremerton, Washington) |
| ABSTRACT | A system for joining door modules comprising modular elements and attachable components, including a male end adapted to join a single-piece female end by rotating the male end into the single-piece female end such that data bus terminals align and power bus terminals align. The system can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed systems for each mission. The joints connecting the modules are designed such that power and data connections between modules are reliably made. |
| FILED | Wednesday, July 19, 2023 |
| APPL NO | 18/224026 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/04 (20130101) Original (OR) Class B63G 2008/002 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/91 (20130101) H01R 12/7005 (20130101) H01R 13/64 (20130101) H01R 13/641 (20130101) H01R 13/6205 (20130101) H01R 13/7175 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151791 | Seeley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| INVENTOR(S) | Eric Seeley (Seebeck, Washington); Jacob Snow (Bremerton, Washington) |
| ABSTRACT | A system for joining charged scuttle modules comprising modular elements and attachable components, including a male end adapted to join a single-piece female end by rotating the male end into the single-piece female end such that data bus terminals align and power bus terminals align. The system can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed systems for each mission. The joints connecting the modules are designed such that power and data connections between modules are reliably made. |
| FILED | Wednesday, July 19, 2023 |
| APPL NO | 18/224033 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/04 (20130101) Original (OR) Class B63G 2008/002 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/91 (20130101) H01R 12/7005 (20130101) H01R 13/64 (20130101) H01R 13/641 (20130101) H01R 13/6205 (20130101) H01R 13/7175 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151792 | Seeley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| INVENTOR(S) | Eric Seeley (Seebeck, Washington); Jacob Snow (Bremerton, Washington) |
| ABSTRACT | A system for joining light-communication modules comprising modular elements and attachable components, including a male end adapted to join a single-piece female end by rotating the male end into the single-piece female end such that data bus terminals align and power bus terminals align. The system can be assembled from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed systems for each mission. The joints connecting the modules are designed such that power and data connections between modules are reliably made. |
| FILED | Wednesday, July 19, 2023 |
| APPL NO | 18/224052 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/04 (20130101) Original (OR) Class B63G 2008/002 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/91 (20130101) H01R 12/7005 (20130101) H01R 13/64 (20130101) H01R 13/641 (20130101) H01R 13/6205 (20130101) H01R 13/7175 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151793 | Seeley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| INVENTOR(S) | Eric Seeley (Seebeck, Washington); Jacob Snow (Bremerton, Washington) |
| ABSTRACT | A system for configuring mission-dependent vehicle assemblies comprising modular elements and attachable components, including a male end adapted to join a single-piece female end by rotating the male end into the single-piece female end such that data bus terminals align and power bus terminals align. The system can be configured from these modular elements and components to meet desired mission and performance characteristics without the need to purchase specially designed systems for each mission. The joints connecting the modules are designed such that power and data connections between modules are reliably made. |
| FILED | Tuesday, September 05, 2023 |
| APPL NO | 18/242507 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/001 (20130101) B63G 8/04 (20130101) Original (OR) Class B63G 2008/002 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/91 (20130101) H01R 12/7005 (20130101) H01R 13/64 (20130101) H01R 13/641 (20130101) H01R 13/6205 (20130101) H01R 13/7175 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151822 | Silberg |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Eric J. Silberg (Potomac, Maryland) |
| ABSTRACT | An exemplary inventive parafoil includes a soft wing and a semi-rigid skeleton. Configured to effect ram-air flight, the soft wing forms adjacent elongate cells directed from leading edge to trailing edge, with respective inflow vents arranged along the leading edge. The semi-rigid skeleton includes one or more cell-compatible support structures, each joined with a cell in furtherance of maintaining the cell's inflated shape and preventing its collapse under adverse aerodynamic circumstances. Each cell-compatible support structure includes a ring-like frame and two parallel rod-like projections attached perpendicular to the ring-like frame at laterally opposite locations. According to each coupling of a cell-compatible support structure with a cell, the ring-like frame is affixed at or near the cell's inflow vent, fitting onto or inside the cell lip; the two rod-like projections extend backward from the ring-like frame along part of the cell length, each integrated with or interiorly contiguous to the cell. |
| FILED | Monday, September 20, 2021 |
| APPL NO | 17/478997 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 17/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152003 | Harvey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Benjamin G. Harvey (Ridgecrest, California); Joseanne Dee Woodroffe (Ridgecrest, California) |
| ABSTRACT | The present invention provides a novel method for chemoselectively hydrogenating cyclic monoterpene precursors with reduced PtO2 at low temperatures, to yield products in which the alkene groups are saturated while the cyclopropane rings from the parent hydrocarbons are conserved. |
| FILED | Thursday, March 30, 2023 |
| APPL NO | 18/128520 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/44 (20130101) B01J 23/56 (20130101) Acyclic or Carbocyclic Compounds C07C 5/03 (20130101) Original (OR) Class C07C 5/10 (20130101) C07C 7/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152031 | Bhattacharjee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BIOVERSYS AG (Basel, Switzerland) |
| ASSIGNEE(S) | BIOVERSYS AG (Basel, Switzerland) |
| INVENTOR(S) | Ashoke Bhattacharjee (Cheshire, Connecticut); Erin M. Duffy (Deep River, Connecticut); Trudy Grossman (New Haven, Connecticut); Joseph A. Ippolito (Guilford, Connecticut); Zoltan F. Kanyo (North Haven, Connecticut) |
| ABSTRACT | The present disclosure relates to methods of treating, preventing, reducing the risk of, or delaying the onset of microbial infections in humans and animals that are caused by or involves one or more microorganisms which are capable of being used as biological weapons, the method including administering a pyrrolocytosine compound or a tautomer thereof or a pharmaceutically acceptable salt of the compound or tautomer. |
| FILED | Thursday, June 06, 2019 |
| APPL NO | 16/972775 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152106 | Martin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Brett D. Martin (Washington, District of Columbia); Jeffrey R. Deschamps (Washington, District of Columbia); Jeffrey C. DePriest (Washington, District of Columbia); Ian D. Giles (Alexandria, Virginia) |
| ABSTRACT | A new, thermally stable conducting material, poly(3-amino-1H-pyrazole-4-carboxylate), can be used in a variety of applications such as thermoelectrics, electron acceptors in light-harvesting (photovoltaic) materials, and thermally stable conducting energetic materials. Related compounds include poly 3-amino-5-chloro-1H-pyrazole-4-carboxylate, poly 3-amino-5-bromo-1H-pyrazole-4-carboxylate, poly 3-amino-5-fluoro-1H-pyrazole-4-carboxylate, poly 3-amino-5-iodo-1H-pyrazole-4-carboxylate, poly 3, 5-diamino-1H-pyrazole-4-carboxylate, poly 3-amino-5-NHR1-1H-pyrazole-4-carboxylate, poly 3-amino-5-NR2-1H-pyrazole-4-carboxylate, or poly 3-amino-5-hydroxy-1H-pyrazole-4-carboxylate. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/347050 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152156 | Timler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Science Applications International Corporation (Reston, Virginia) |
| ASSIGNEE(S) | Science Applications International Corporation (Reston, Virginia) |
| INVENTOR(S) | John Timler (River Ridge, Louisiana); Xingcun C. Tong (Reston, Virginia) |
| ABSTRACT | Self-sintering conductive inks can be printed and self-sintered with a simple and low-cost process mechanized by exothermic alkali metal and water reaction, with enhanced electrical and thermal performance by liquid metal fusion. Such self-sintering conductive inks may include a gallium-alkali metal component and a water absorbing gel component. After patterning, the self-sintering inks, on reaching a designed trigger temperature (including room temperature), may metallize through a two-step process. Initially the gallium-alkali metal component activates and reacts with water released from the water absorbing gel component. Then the exothermic reaction between the water and the alkali element creates an intense and highly localized heating effect, which liquefies all metallic components in the ink and, on cooling, creates a solid metal trace or interconnect. Post cooling, the metal trace or interconnect cannot be reflowed without a significant temperature increase or other energetic input. |
| FILED | Wednesday, March 24, 2021 |
| APPL NO | 17/211248 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/033 (20130101) C09D 11/38 (20130101) C09D 11/52 (20130101) Original (OR) Class C09D 11/102 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152241 | Ting et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Aalborg University (Aalborg, Denmark) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Aalborg University (Aalborg, Denmark) |
| INVENTOR(S) | David T. Ting (Dover, Massachusetts); Daniel A. Haber (Chestnut Hill, Massachusetts); Shyamala Maheswaran (Lexington, Massachusetts); Francesca Bersani (Turin, Italy); Anders M. Naar (Arlington, Massachusetts); Mihir Shivadatta Rajurkar (Worcester, Massachusetts); Sakari Kauppinen (Holte, Denmark); Andreas Petri (Frederiksberg, Denmark) |
| ABSTRACT | Methods for treating cancer, e.g., cancer of epithelial origin, by specifically targeting human satellite II (HSATII) using sequence specific agents such as oligonucleotides. |
| FILED | Wednesday, April 24, 2019 |
| APPL NO | 16/393557 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/341 (20130101) C12N 2310/3231 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152242 | Duan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri); THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH (Rockville, Maryland) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri); The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | Dongsheng Duan (Columbia, Missouri); Chady Hakim (Columbia, Missouri); Nalinda B. Wasala (Columbia, Missouri); Yongping Yue (Columbia, Missouri) |
| ABSTRACT | Disclosed herein are methods for systemically editing a gene in a subject and for systemically treating a genetic condition in a subject using a dual-vector CRISPR-Cas therapy. The methods comprise administering to the subject, via systemic administration, a gene editing AAV vector encoding a CRISPR effector protein (e.g., a Cas protein) and a targeting AAV vector providing one or more gRNAs targeted to the gene. In the methods, the ratio of the targeting AAV vector to the gene editing vector is greater than or equal to 2. Also provided are dual-vector systems for editing a gene or treating a genetic disease in a subject. |
| FILED | Tuesday, April 23, 2019 |
| APPL NO | 17/049980 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/86 (20130101) C12N 15/102 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2320/32 (20130101) C12N 2750/14141 (20130101) C12N 2830/008 (20130101) C12N 2830/50 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152270 | Lyte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa); REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa); REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Mark Lyte (Ames, Iowa); David Robert Brown (Saint Paul, Minnesota) |
| ABSTRACT | The present invention is directed to methods of probiotic selection and use based on the capability of microbial biogenic amine uptake as a method for targeted clinical and veterinary applications, including promoting health and well-being and/or treating therapeutic conditions. The present invention utilizes a microbially-focused approach for the development of drug selection and/or probiotic administration in a variety of diseases and disorders. |
| FILED | Monday, February 01, 2021 |
| APPL NO | 17/248641 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/135 (20130101) A61K 31/138 (20130101) A61K 31/381 (20130101) A61K 31/4709 (20130101) A61K 35/747 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) C12Q 1/025 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2500/10 (20130101) G01N 2800/52 (20130101) G01N 2800/304 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152867 | Fries et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul Fries (Owensburg, Indiana); Nicholas Uebelhor (Jasper, Indiana); Austin D. Schulte (Bloomfield, Indiana); Michael C. Jones (Loogootee, Indiana) |
| ABSTRACT | Provided are systems, apparatus, and methods for pushing out and drilling a flare grain in an aerial flare. The system includes at least three stands including a first stand holding a first electric linear actuator positioned to interface with the aerial flare and push out a flare grain of the flare. The second stand holds the aerial flare and is positioned relative to the first stand to facilitate interface of the flare with the first electric linear actuator. The third stand includes a drill and is movable relative to the second stand for drilling a hole in the flare grain. A second electric linear actuator is coupled to the third stand device moves the third stand device relative the second stand to enable the drill to engage with the flare grain. The system also includes a controller/processor automating the pushing and drilling operations by controlling the electric linear actuators. |
| FILED | Wednesday, May 03, 2023 |
| APPL NO | 18/142609 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 4/26 (20130101) F42B 33/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152968 | Harshman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Sean Harshman (Fairborn, Ohio); Mark Hawkins (Tipp City, Ohio) |
| ABSTRACT | A flow regulation device for volatile and semi-volatile sampling onto adsorbent media is provided. The flow regulation device includes a housing having an inlet, an outlet, a secondary inlet that is open to the ambient, a real time flow meter, a controller in electronic communication with the flow meter, and a three-way valve. Gas is drawn through the adsorbent media, into the inlet, and then to the outlet by a vacuum source joined to the outlet. The controller is configured to: (1) actuate the three-way valve to put the vacuum source in-line with the inlet; (2) continuously monitor the flow of gas through the inlet and calculate the time necessary to sample a pre-set volume of gas; and (3) after the pre-set volume of gas passes through the inlet, actuate the three-way valve to put the vacuum source in-line with the secondary inlet. |
| FILED | Tuesday, June 14, 2022 |
| APPL NO | 17/839524 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/24 (20130101) Original (OR) Class G01N 2001/248 (20130101) G01N 2001/2244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152988 | Kelley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| INVENTOR(S) | Mathew L. Kelley (Columbia, South Carolina); Andrew B. Greytak (Columbia, South Carolina); M V S Chandrashekhar (Columbia, South Carolina) |
| ABSTRACT | Spatially resolved Fourier Transform Impedance Spectroscopy (FTIS) is disclosed to spatially map and quickly build the frequency response of optoelectronic devices using optical probes. The transfer function of a linear system is the Fourier transform of its impulse response, which may be obtained from transient photocurrent measurements of devices such as photodetectors and solar cells. We apply FTIS to a PbS colloidal quantum dot (QD)/SiC heterojunction photodiode and corroborate results using intensity-modulated photocurrent spectroscopy. The cutoff frequencies of the QD/SiC devices were as high as ˜10 kHz, demonstrating their utility in advanced flexible and thin film electronics. The practical frequencies for FTIS lie in the mHz-kHz range, ideal for composite or novel materials such as QD films that are dominated by interfacial trap states. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/688230 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6452 (20130101) Original (OR) Class G01N 21/6456 (20130101) G01N 2021/6423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153032 | Strong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Veronica Strong (Portland, Oregon); Maher F. El-Kady (Los Angeles, California); Richard B. Kaner (Pacific Palisades, California) |
| ABSTRACT | An interconnected corrugated carbon-based network comprising a plurality of expanded and interconnected carbon layers is disclosed. In one embodiment, each of the expanded and interconnected carbon layers is made up of at least one corrugated carbon sheet that is one atom thick. In another embodiment, each of the expanded and interconnected carbon layers is made up of a plurality of corrugated carbon sheets that are each one atom thick. The interconnected corrugated carbon-based network is characterized by a high surface area with highly tunable electrical conductivity and electrochemical properties. |
| FILED | Monday, July 25, 2022 |
| APPL NO | 17/872380 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 3/26 (20130101) B32B 3/28 (20130101) B32B 9/007 (20130101) B32B 9/041 (20130101) B32B 9/045 (20130101) B32B 18/00 (20130101) B32B 27/32 (20130101) B32B 2307/75 (20130101) B32B 2307/202 (20130101) B32B 2307/732 (20130101) B32B 2429/02 (20130101) B32B 2457/00 (20130101) B32B 2457/08 (20130101) B32B 2457/10 (20130101) B32B 2457/12 (20130101) B32B 2457/20 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/23 (20170801) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 2237/72 (20130101) C04B 2237/086 (20130101) C04B 2237/363 (20130101) C04B 2237/592 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/0037 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 5/02 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Technologies for Adaptation to Climate Change Y02A 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153162 | Cambrea et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Lee R. Cambrea (Bloomington, Indiana); Terry L. Chastain (Bedford, Indiana); Zachary A. Masner (Bloomington, Indiana); Eric Alan Hillenbrand (Evansville, Indiana) |
| ABSTRACT | Disclosed are apparatus and methods for determining a radar cross section (RCS) of countermeasure units such as chaff that utilizes ground level testing. An antenna platform is provided that is mounted to a support member at ground level and includes a radar transmit antenna disposed on the antenna platform, a radar receive antenna disposed on the antenna platform, and radar attenuating material disposed on the antenna platform linearly between the transmit antenna and the receive antenna for attenuating linear transmission of signals between the transmit antenna to the receive antenna. Additionally, low power transmitters used to enable safe ground testing are coupled to the transmit antenna for transmitting radar RF signals toward dispersed countermeasure units above the platform and also network analyzers coupled to the receive antenna that are capable of measuring the low power RF signals reflected by the dispersed countermeasure units. |
| FILED | Friday, February 18, 2022 |
| APPL NO | 17/674971 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/038 (20130101) G01S 7/41 (20130101) Original (OR) Class G01S 13/88 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153235 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Young L Kim (West Lafayette, Indiana); Yunsang Kwak (Gyeongsangbuk-do, South Korea); Jungwoo Leem (West Lafayette, Indiana) |
| ABSTRACT | An Anderson localized hyperspectral filter array is disclosed which includes a base layer and a plurality of optical layers deposited on the base layer selected from two or more materials, each material having a refractive index that is different from the other materials of the two or more materials, wherein no consecutively deposited optical layers have the same refractive index, each of the plurality of optical layers having a thickness chosen based on a random number within a predetermined range. |
| FILED | Wednesday, November 03, 2021 |
| APPL NO | 17/518386 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/285 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153932 | More et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Ankit More (San Mateo, California); Fabrizio Petrini (Menlo Park, California); Robert Pawlowski (Beaverton, Oregon); Shruti Sharma (Hillsboro, Oregon); Sowmya Pitchaimoorthy (Hillsboro, Oregon) |
| ABSTRACT | Examples include techniques for an in-network acceleration of a parallel prefix-scan operation. Examples include configuring registers of a node included in a plurality of nodes on a same semiconductor package. The registers to be configured responsive to receiving an instruction that indicates a logical tree to map to a network topology that includes the node. The instruction associated with a prefix-scan operation to be executed by at least a portion of the plurality of nodes. |
| FILED | Monday, December 21, 2020 |
| APPL NO | 17/129555 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4411 (20130101) Original (OR) Class G06F 13/4022 (20130101) G06F 13/4027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154003 | Inoue et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Ken Inoue (Elmsford, New York); Maika Takita (Croton-on-Hudson, New York); Antonio Corcoles-Gonzalez (Mount Kisco, New York); Scott Douglas Lekuch (New York, New York) |
| ABSTRACT | Systems, computer-implemented methods, and computer program products that can facilitate determining a state of a qubit are described. According to an embodiment, a system can comprise a memory that stores computer executable components and a processor that executes the computer executable components stored in the memory. The computer executable components can comprise an output receiving component that can receive, in response to a request, output representative of a quantum state of a qubit of a quantum computing device, and a classifying component that classifies the quantum state of the qubit of the quantum computing device based on the output representative of the quantum state of the qubit. The system can further include a configuring component that can configure the classifying component based on a characteristic of the request. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/183602 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) G06F 18/2411 (20230101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class G06N 10/20 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154005 | Monroe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| INVENTOR(S) | Christopher Monroe (Ellicott City, Maryland); Marko Cetina (College Park, Maryland); Norbert Linke (Stevenson, Maryland); Shantanu Debnath (College Park, Maryland) |
| ABSTRACT | The disclosure describes various aspects of optical control of atomic quantum bits (qubits) for phase control operations. More specifically, the disclosure describes methods for coherently controlling quantum phases on atomic qubits mediated by optical control fields, applying to quantum logic gates, and generalized interactions between qubits. Various attributes and settings of optical/qubit interactions (e.g., atomic energy structure, laser beam geometry, polarization, spectrum, phase, background magnetic field) are identified for imprinting and storing phase in qubits. The disclosure further describes how these control attributes are best matched in order to control and stabilize qubit interactions and allow extended phase-stable quantum gate sequences. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/305954 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Optical Computing Devices; G06E 1/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154319 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Edward Chen (Stanford, California); John Galeotti (Pittsburgh, Pennsylvania); Howie Choset (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided is a method of training a machine-learning-based artificial intelligence (AI) model to handle diverse types of motions occurring during image acquisition, including capturing image data including motion between an imaging device and tissue, modifying the captured image data, resulting in modified image data, by at least one of: altering an amount of time between any two frames; removing a subsequence of frames from the captured image data; and adding a subsequence of one or more new frames to the captured image data, and training a machine-learning-based AI model based on the modified image data. Other systems and methods are also described. |
| FILED | Monday, November 15, 2021 |
| APPL NO | 18/036737 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/0464 (20230101) Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/774 (20220101) Original (OR) Class G06V 2201/03 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154717 | Chu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | THE MITRE CORPORATION (McLean, Virginia) |
| INVENTOR(S) | Alejandro Chu (Madison, Alabama) |
| ABSTRACT | Fabricating composite monolithic structures to achieve optimal electrical, thermal, and mechanical properties through the elimination of air is discussed herein. A method of fabricating a composite structure includes coating an insulating layer with an uncured binding material and performing a first curing process on the uncured binding material to form a first stage cured binding material on the insulating layer without introduction of air pockets in a conventional manufacturing atmospheric environment. The method further includes disposing the insulating layer on an array of conductive structures. The first stage cured binding material is positioned between the insulating layer and the array of conductive structures. The method further includes performing a second curing process on the first stage cured binding material to form a cured binding material, and forming cured regions between adjacent conductive structures of the array of conductive structures. |
| FILED | Tuesday, August 11, 2020 |
| APPL NO | 16/990408 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 5/06 (20130101) Original (OR) Class H01F 19/00 (20130101) H01F 27/288 (20130101) H01F 27/323 (20130101) H01F 41/122 (20130101) H01F 41/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154956 | Kantarovsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GlobalFoundries U.S. Inc. (Malta, New York) |
| ASSIGNEE(S) | GlobalFoundries U.S. Inc. (Malta, New York) |
| INVENTOR(S) | Johnatan Avraham Kantarovsky (South Burlington, Vermont); Rajendran Krishnasamy (Essex Junction, Vermont); Mark D. Levy (Williston, Vermont); John J. Ellis-Monaghan (Grand Isle, Vermont); Michael J. Zierak (Colchester, Vermont); Kristin Marie Welch (Essex, Vermont) |
| ABSTRACT | Disclosed are a structure with a multi-level field plate and a method of forming the structure. The field plate includes multiple first conductors on a dielectric layer and separated from each other by spaces with different widths (e.g., by with progressively decreasing widths). A conformal additional dielectric layer extends over the first conductors and onto the dielectric layer within the spaces. The field plate also includes, on the additional dielectric layer, second conductor(s) with portions thereof extending into the spaces. Within the spaces, the second conductor portions are at different heights (e.g., at progressively increasing heights) above the dielectric layer. Such a field plate can be incorporated into a transistor (e.g., a high electron mobility transistor (HEMT)) to, not only reduce the peak of an electric field exhibited proximal to a gate terminal, but to ensure the electric field is essentially uniform level between the gate and drain terminals. |
| FILED | Thursday, April 11, 2024 |
| APPL NO | 18/632902 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/401 (20130101) H01L 29/404 (20130101) Original (OR) Class H01L 29/2003 (20130101) H01L 29/7786 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154961 | Troughton |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GlobalFoundries U.S. Inc. (Malta, New York) |
| ASSIGNEE(S) | GlobalFoundries U.S. Inc. (Malta, New York) |
| INVENTOR(S) | Samuel Troughton (Burlington, Vermont) |
| ABSTRACT | Structures including an ohmic contact for a high-electron-mobility transistor and methods of forming such structures. The structure comprises a layer stack on a substrate and a device structure including an ohmic contact. The layer stack includes a plurality of semiconductor layers each comprising a compound semiconductor material. The ohmic contact includes a metal layer in a contacting relationship with a portion of at least one of the semiconductor layers of the layer stack and a region comprising oxygen atoms, and the metal layer is positioned between the region and the portion of the at least one of the semiconductor layers of the layer stack. |
| FILED | Thursday, June 13, 2024 |
| APPL NO | 18/742692 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/401 (20130101) H01L 29/452 (20130101) Original (OR) Class H01L 29/2003 (20130101) H01L 29/7786 (20130101) H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155068 | Oh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Hyukkeun Oh (Boulder, Colorado); Se-Hee Lee (Superior, Colorado); Joshua Buettner-Garrett (Arvada, Colorado) |
| ABSTRACT | A solid-state battery includes an anode material including silicon or tin. The anode material may include silicon and/or tin in various forms including layers or intermixed particles of various phases and crystallinity. |
| FILED | Tuesday, October 16, 2018 |
| APPL NO | 16/756686 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/38 (20130101) H01M 4/48 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) H01M 4/382 (20130101) H01M 4/386 (20130101) H01M 4/387 (20130101) Original (OR) Class H01M 10/0562 (20130101) H01M 10/0565 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155128 | Kalateh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Mohammad Mahdi Honari Kalateh (Middleton, Wisconsin); Nader Behdad (Oregon, Wisconsin); John H. Booske (McFarland, Wisconsin) |
| ABSTRACT | A phase shift element includes an antenna, a first dielectric layer, a ground plane mounted to a first surface of the first dielectric layer, a reflecting circuit, and a single antenna-reflector line connected between the antenna and the reflecting circuit through the ground plane and the first dielectric layer. The antenna-reflector line is formed of a conducting material. The reflecting circuit is mounted to a second surface of the first dielectric layer. The first surface is opposite the second surface. The reflecting circuit is configured to reflect a signal received on the single antenna-reflector line from the antenna back to the antenna on the single antenna-reflector line. The reflecting circuit is further configured to be switchable between two different impedance levels that each provide a different phase shift when the signal is reflected by the reflecting circuit. |
| FILED | Tuesday, January 04, 2022 |
| APPL NO | 17/567965 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/46 (20130101) Original (OR) Class H01Q 15/147 (20130101) H01Q 19/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155203 | Rambaran |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Rishi Rambaran (Huntington Station, New York) |
| ABSTRACT | A system for front end protection of an RF receiver against interfering pulsed high power RF signals includes a dual-diode device comprising a first Transient Voltage Suppressor (TVS) diode; and a second TVS diode; wherein the first TVS diode and the second TVS diode are located between an RF input/output and an RF receiver front end. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 17/848812 |
| ART UNIT | 2839 — Electrical Circuits and Systems |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/78 (20130101) Emergency Protective Circuit Arrangements H02H 9/042 (20130101) Original (OR) Class H02H 9/044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155227 | Assawaworrarit et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Sid Assawaworrarit (Redwood City, California); Shanhui Fan (Stanford, California) |
| ABSTRACT | In certain examples, methods and semiconductor structures are directed to an apparatus including source circuitry configured to provide power to other circuitry, with the source circuitry including amplification circuitry (e.g., with a power-switching output) and a source resonator. The amplification circuitry is to provide power to the source resonator with a gain that is dependent on a coupling rate between the source circuitry and other external-receiving circuitry. The source circuitry is also to offset phase delay caused by the amplifier. In operation, the source resonator generates a magnetic field in response to the power, for highly-efficient wirelessly transfer of the power to the other circuitry. |
| FILED | Friday, October 23, 2020 |
| APPL NO | 17/771296 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/05 (20160201) H02J 50/12 (20160201) Original (OR) Class H02J 50/40 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155321 | Hansen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Thomas E Hansen (Newport, Rhode Island) |
| ABSTRACT | An axial motor assembly is provided with fluidic electrostatic actuators mounted between an end plate and a wobble plate. A computer-implemented drive subsystem executes instructions to create voltage delivery patterns through a power supply to operate the actuators to create nutational motion in the wobble plate. A cam transfers the nutational motion into rotational motion and, in turn, into shaft power. The actuators can be linearly-contractile shelled electrostatic actuators, linearly expansive donut electrostatic actuators and multi-directionally expansive segmented donut electrostatic actuators. Drive method steps include initializing drive variables; determining, upon detecting a control command, a respective deformation target for each actuator; determining, based on the drive variables and the deformation targets, the voltage delivery pattern; and throttling the power supply to drive the actuators using the voltage delivery pattern. Upon detecting a response change in axial motor operation, drive variables can be dynamically recalibrated. |
| FILED | Thursday, September 22, 2022 |
| APPL NO | 17/950318 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 7/003 (20130101) Electric Machines Not Otherwise Provided for H02N 1/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155447 | Steinbrecher |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Donald H Steinbrecher (Brookline, Massachusetts) |
| ABSTRACT | A method is provided for determining segmented partition capture area by using a minimum detectable signal and a maximum interfering signal calculated from a driving point impedance. A signal channel of an analog-to-digital converter is selected and then a signal channel of a low-noise amplifier is selected in order to reduce the noise for the system using the method. The maximum value of the analog-to-digital noise and the minimum value of the analog-to-digital converter input signal sinewave signal are determined. The signal channel is designed by the use of a channel noise figure, a channel full scale input signal and a channel input impedance. A maximum interfering signal is defined by the channel full scale signal to set a limit on the segmented partition capture area. |
| FILED | Thursday, August 18, 2022 |
| APPL NO | 17/890305 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Transmission H04B 7/0814 (20130101) Original (OR) Class H04B 17/336 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155570 | Brewer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Tony Brewer (Plano, Texas) |
| ABSTRACT | Implementations of the present disclosure are directed to systems and methods for reducing the size of packet headers by using a single field to encode multiple elements. Instead of including separate fields for each element, one or more encoded fields may be used, each of which is decoded to determine two or more values for the data packet. A receiving device decodes the encoded data field to retrieve the two or more values. |
| FILED | Friday, November 18, 2022 |
| APPL NO | 17/990467 |
| ART UNIT | 2415 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/302 (20130101) H04L 45/745 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155738 | Yeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northeastern University (Boston, Massachusetts); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Edmund Meng Yeh (Newton, Massachusetts); Ying Cui (Shaanxi, China PRC); Ran Liu (Heilongjiang, China PRC); Tracey Ho (Pasadena, California); Michael Burd (Lees Summit, Missouri); Derek Leong (Singapore, Singapore) |
| ABSTRACT | A system and method for joint dynamic interest request forwarding and dynamic cache placement and eviction and provided within the context of the Named Data Networking (NDN) architecture. The system and method employ a virtual control plane that operates on the user demand rate for data objects in the network, and an actual plane that handles Interest Packets and Data Packets. Distributed algorithms within the virtual plane achieve network load balancing through dynamic forwarding and caching, thereby maximizing the user demand rate that the NDN network can satisfy. A method of congestion control is also provided to achieve optimal network fairness using the VIP framework. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/683931 |
| ART UNIT | 2449 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/02 (20130101) H04L 45/64 (20130101) H04L 45/586 (20130101) H04L 47/27 (20130101) H04L 67/568 (20220501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155951 | Black et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nu-Trek, Inc. (San Diego, California) |
| ASSIGNEE(S) | Nu-Trek, Inc (San Diego, California) |
| INVENTOR(S) | Stephen Holden Black (Tennessee Ridge, Tennessee); Paul Richard Behmen (Chester, California); Francisco Tejada (Kingsville, Maryland) |
| ABSTRACT | A photodetector interface circuit is described, residing partially or fully within a unit cell per pixel of an FPA. The interface circuit uses an innovative approach to providing pixel level digitization for full frame integration times while maintaining the ability to use integration capacitors of practical sizes. The technique uses successive charge subtraction, removing charge from an integration capacitor successively, triggered by the charge increasing sufficiently to charge the integrator to a reference level, thereby triggering both charge removal and incrementing a count, until all of the current flowing in the photodetector has been accounted for and the count represents the digitization of the photodetector signal. Various options on how to arrange the digitization elements are also disclosed. |
| FILED | Friday, February 17, 2023 |
| APPL NO | 18/111257 |
| ART UNIT | 2638 — Computer Networks |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) G01J 5/20 (20130101) G01J 2005/202 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 19/0038 (20130101) Pictorial Communication, e.g Television H04N 25/77 (20230101) Original (OR) Class H04N 25/78 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156338 | Gerasopoulos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Konstantinos Gerasopoulos (Gambrills, Maryland); Jason E. Tiffany (Columbia, Maryland); Seppo J. Lehtonen (Columbia, Maryland); Vanessa O. Rojas (Columbia, Maryland); Spencer A. Langevin (Silver Spring, Maryland); Bing Tan (Ann Arbor, Michigan) |
| ABSTRACT | An apparatus for mounting on a circuit board is provided. The apparatus may include a circuit board mount packaging and a battery. The circuit board mount packaging may include a cavity, a first internal lead, and a second internal lead. The first internal lead may be connect to a first external pin and the second internal lead may be connected to a second external pin. The battery may be disposed within the cavity of the circuit board mount packaging. The battery may comprise an anode and a cathode. The anode may be wire bond connected to the first internal lead and the cathode may be wire bond connected to the second internal lead. |
| FILED | Friday, December 16, 2022 |
| APPL NO | 18/082924 |
| ART UNIT | 2848 — Electrical Circuits and Systems |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0431 (20130101) H01M 10/0468 (20130101) H01M 10/6569 (20150401) H01M 50/105 (20210101) H01M 50/519 (20210101) H01M 2300/0082 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/181 (20130101) Original (OR) Class H05K 2201/10037 (20130101) H05K 2201/10568 (20130101) H05K 2201/10628 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12151212 | Loprete |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COMPACT MEMBRANE SYSTEMS INC. (Newport, Delaware) |
| ASSIGNEE(S) | Compact Membrane Systems, Inc. (Newport, Delaware) |
| INVENTOR(S) | Kenneth Evan Loprete (Cherry Hill, New Jersey) |
| ABSTRACT | An improved method for humidification of a facilitated-transport membrane incorporates delivering a non-selective hydration fluid incorporating liquid water to a permeate side of a pressure vessel containing the facilitated transport membrane. The non-selective hydration fluid includes water and may be configured on the permeate side interface of the facilitated-transport membrane as a liquid or a gas. A process for separation of components in a gaseous mixture utilizing the method for humidification produces higher permeation of gasses through the facilitated transport membrane. The non-selective hydration fluid may be static or flowing and is non-selective for the permeance of certain permeate-gas components over other components. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 17/276639 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 63/10 (20130101) B01D 65/00 (20130101) Original (OR) Class B01D 71/32 (20130101) Acyclic or Carbocyclic Compounds C07C 7/144 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151230 | Sadow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa); CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Ames, Iowa); CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Aaron D. Sadow (Ames, Iowa); Wenyu Huang (Ames, Iowa); Frédéric A. Perras (Ames, Iowa); Marek Pruski (Ames, Iowa); Akalanka Tennakoon (Ames, Iowa); Xun Wu (Ames, Iowa); Anne M. Lapointe (Ithaca, New York) |
| ABSTRACT | Disclosed herein is a catalyst which comprises a silica core having an outer surface and a mesoporous silica shell having an outer surface and an inner surface with the inner surface being inside the outer surface of said mesoporous silica shell proximate to and surrounding the outer surface of said silica core. Wherein the outer surface of the mesoporous silica shell has openings leading to pores within the mesoporous silica shell which extend toward the outer surface of said silica core. The catalyst also includes catalytically active metal nanoparticles positioned within the pores proximate to said core, wherein the catalytic metal nanoparticles comprise about 0.0001 wt % to about 1.0 wt % of the catalyst. Also disclosed are methods of making the catalyst and using it to carry out a process for catalytically hydrogenolysizing a polyolefinic polymer. |
| FILED | Monday, November 13, 2023 |
| APPL NO | 18/508055 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/08 (20130101) B01J 23/42 (20130101) Original (OR) Class B01J 35/40 (20240101) B01J 35/50 (20240101) B01J 35/647 (20240101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 11/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151231 | Hu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, College Park (College Park, Maryland); The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Liangbing Hu (Rockville, Maryland); Chao Wang (Baltimore, Maryland); Pengfei Xie (Baltimore, Maryland); Yonggang Yao (College Park, Maryland) |
| ABSTRACT | A catalytic structure has a plurality of high-entropy alloy (HEA) nanoparticles. Each HEA nanoparticle is composed of a homogeneous mixture of elements of cobalt (Co), molybdenum (Mo), and at least two transition metal elements. For example, in some embodiments, each HEA nanoparticle is a quinary mixture of Co, Mo, iron (Fe), nickel (Ni), and copper (Cu). The homogeneous mixture in each HEA nanoparticle forms a single solid-solution phase. The catalytic structure is used to catalyze a chemical reaction, for example, ammonia decomposition or ammonia synthesis. Methods for forming the catalytic structure are also disclosed. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/466781 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/28 (20130101) B01J 23/72 (20130101) B01J 23/75 (20130101) B01J 23/745 (20130101) B01J 23/755 (20130101) Original (OR) Class B01J 35/19 (20240101) B01J 35/40 (20240101) B01J 37/08 (20130101) B01J 37/0215 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151247 | Henzl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Vladimir Henzl (Los Alamos, New Mexico); Rollin Lakis (Los Alamos, New Mexico); Sylvia Ann Junghans (Los Alamos, New Mexico) |
| ABSTRACT | A rapidly curable liquid gel for collecting an analyte from a sampling surface includes a polymer precursor mixture including a monomer and/or an oligomer; and an additive to enhance extraction of the analyte from the sampling surface. A kit for collecting an analyte from a sampling surface may include the rapidly curable liquid gel and a portable device for rapidly curing the gel. The rapidly curable liquid gel is cured to thereby form a peelable sampling film, and the sampling film is removed from the sampling surface, thereby collecting the analyte. In one embodiment, the rapidly curable liquid gel is UV-curable, the polymer precursor mixture further includes a photoinitiator compound, and the portable device includes a UV light source configured to emit UV light of a wavelength range absorbed by the photoinitiator compound. |
| FILED | Monday, January 04, 2021 |
| APPL NO | 17/141107 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 7/52 (20130101) Original (OR) Class B01L 2300/069 (20130101) B01L 2300/0825 (20130101) B01L 2300/1861 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) G01N 2001/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151937 | Rupp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Xerox Corporation (Norwalk, Connecticut) |
| INVENTOR(S) | Bradley Rupp (San Francisco, California); Mary Louie (Menlo Park, California); Jin Ki Hong (Palo Alto, California); Dane Boysen (Anchorage, Alaska) |
| ABSTRACT | A method of producing hydrogen may include: providing a catalyst-carbon gel; and flowing a hydrocarbon through a catalyst, wherein catalyst is a metal or mixture of metals that is non-wetting to solid carbon at 1 bar absolute and 10° C. above a melting point of the metal or mixture of metals. |
| FILED | Tuesday, June 28, 2022 |
| APPL NO | 17/852176 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/06 (20130101) B01J 35/23 (20240101) Non-metallic Elements; Compounds Thereof; C01B 3/26 (20130101) Original (OR) Class C01B 2203/0277 (20130101) C01B 2203/1005 (20130101) C01B 2203/1076 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151945 | Garzon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
| INVENTOR(S) | Fernando Garzon (Albuquerque, New Mexico); Shekar Balagopal (Salt Lake City, Utah) |
| ABSTRACT | An electrolytic cell and method for synthesizing ammonia by utilizing a lithium selective membrane in the electrolytic cell and providing at least one lithium halogen salt as an electrolyte in the electrochemical process of producing ammonia. The reaction utilizes a hydrogen halide or hydrogen sulfide as a hydrogen oxidant in the process, and allows the regeneration of lithium halide salts that can be recycled back into the cell reaction. |
| FILED | Tuesday, January 22, 2019 |
| APPL NO | 16/963760 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/04 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/02 (20130101) Original (OR) Class Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 1/27 (20210101) C25B 9/19 (20210101) C25B 13/07 (20210101) C25B 15/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151959 | Demirtas |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Meltem Urgun Demirtas (Naperville, Illinois) |
| ABSTRACT | Provided herein are methods of organic waste stream conversion including fermenting an organic waste stream with an inoculum using arrested methanogenesis to generate an organic product. The inoculum includes an anaerobic consortium isolated from cheese, yogurt, saline soil, kefir, and/or probiotics and the anaerobic consortium is pretreated to transform the anaerobic consortium into an acidogenic consortium. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/249608 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Separation B01D 15/363 (20130101) B01D 61/025 (20130101) B01D 61/027 (20130101) B01D 2315/10 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 3/28 (20130101) C02F 3/341 (20130101) Original (OR) Class C02F 11/04 (20130101) C02F 2103/32 (20130101) C02F 2103/327 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/08 (20130101) C12P 7/40 (20130101) C12P 7/52 (20130101) C12P 7/54 (20130101) C12P 7/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152163 | Monickam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PIXELLIGENT TECHNOLOGIES LLC (Baltimore, Maryland) |
| ASSIGNEE(S) | PIXELLIGENT TECHNOLOGIES LLC (Baltimore, Maryland) |
| INVENTOR(S) | Selina Monickam (Takoma Park, Maryland); Darryl Peters (, None); Gregory Cooper (Fulton, Maryland); Zhiyun Chen (Olney, Maryland); Robert Swisher (Baltimore, Maryland) |
| ABSTRACT | The present disclosure provides a high refractive index acrylic formulation embedded with sub-10 nm metal oxide nanocrystals. The formulation is ideal for high refractive index, high transparency coating for a variety of optical applications including OLED lighting. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/321289 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 3/22 (20130101) C08K 9/04 (20130101) C08K 9/06 (20130101) C08K 2003/2244 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 33/06 (20130101) C08L 33/10 (20130101) C08L 33/10 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/004 (20130101) Original (OR) Class C09D 7/20 (20180101) C09D 7/62 (20180101) C09D 7/67 (20180101) C09D 11/033 (20130101) C09D 11/037 (20130101) C09D 11/101 (20130101) C09D 11/107 (20130101) C09D 135/02 (20130101) Optical Elements, Systems, or Apparatus G02B 1/111 (20130101) Organic electric solid-state devices H10K 50/854 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152293 | Suzuki et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GE Infrastructure Technology LLC (Greenville, South Carolina) |
| INVENTOR(S) | Akane Suzuki (Ballston Spa, New York); Bernard Patrick Bewlay (Niskayuna, New York); Chen Shen (Schenectady, New York); Scott Michael Oppenheimer (Niskayuna, New York); Patrick Thomas Brennan (Niskayuna, New York) |
| ABSTRACT | A niobium-silicide based alloy and a turbine having at least a turbine component formed from the niobium-silicide based alloy are provided. The niobium-silicide based alloy comprises: between about 14 atomic percent and about 24 atomic percent titanium (Ti); between about 11 atomic percent and about 19 atomic percent silicon (Si); between about 4 atomic percent and about 8 atomic percent chromium (Cr); between about 2 atomic percent and about 6 atomic percent hafnium (Hf); up to about 4 atomic percent aluminum (Al); between about 0.5 atomic percent and about 1 atomic percent tin (Sn); between about 5 atomic percent and about 15 atomic percent tantalum (Ta); between about 1 atomic percent and about 5 atomic percent tungsten (W); up to about 5 atomic percent rhenium (Re); up to about 5 atomic percent zirconium (Zr); up to about 6 atomic percent yttrium (Y); and a balance of niobium (Nb). |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/156655 |
| ART UNIT | 1759 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Alloys C22C 27/02 (20130101) Original (OR) Class C22C 32/0078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152532 | Staubach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RTX CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RTX CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Joseph B. Staubach (Colchester, Connecticut); Neil J. Terwilliger (Cheshire, Connecticut); Joseph E. Turney (Amston, Connecticut) |
| ABSTRACT | A turbine engine assembly includes a condenser assembly arranged along the core flow path to extract water from the exhaust gas flow, and an evaporator assembly where thermal energy from the exhaust gas flow is communicated to the water extracted by the condenser assembly to generate a steam flow for injection into the core flow path. The evaporator assembly splits steam generation and cooling functions to increase efficiencies of each function. |
| FILED | Friday, October 13, 2023 |
| APPL NO | 18/486362 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/22 (20130101) F02C 3/30 (20130101) Original (OR) Class F02C 7/14 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2260/213 (20130101) F05D 2270/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152572 | Van de Ven et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | James Van de Ven (Minneapolis, Minnesota); Garrett Bohach (Minneapolis, Minnesota); Nishanth (Madison, Wisconsin); Eric Severson (Middleton, Wisconsin) |
| ABSTRACT | An electric-to-hydraulic conversion machine includes an axial flux electric motor and a hydraulic pump. The motor includes a spindle, at least one rotor configured to rotate about the spindle, and at least one stator configured to drive rotation of the at least one rotor about the spindle. The hydraulic pump includes a piston block having a plurality of cylinders, a plurality of pistons each supported in one of the cylinders of the piston block, and a cam ring. The piston block is attached to the at least one rotor and is configured to rotate about the spindle with rotation of the at least one rotor. The cam ring is configured to radially drive the pistons during rotation of the piston block about the spindle, which drives a fluid flow. |
| FILED | Friday, August 14, 2020 |
| APPL NO | 17/629909 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Positive-displacement Machines for Liquids; Pumps F04B 1/0452 (20130101) F04B 1/0472 (20130101) F04B 7/0007 (20130101) F04B 17/03 (20130101) Original (OR) Class Dynamo-electric Machines H02K 1/2798 (20220101) H02K 7/14 (20130101) H02K 16/02 (20130101) H02K 21/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152809 | Coleman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Terabase Energy, Inc. (Berkeley, California) |
| ASSIGNEE(S) | Terabase Energy, Inc. (Berkeley, California) |
| INVENTOR(S) | Brian Coleman (Portland, Oregon); Adam Hansel (Davis, California); Soren Jensen (Corte Madera, California) |
| ABSTRACT | A clamp is described that couples a torque tube and at least one solar panel within a solar table. The clamp provides an efficient attachment when in a closed position that allows transportation of the solar table from a centralized assembly location to an installation point within a large-scale solar system. The clamp further provides an efficient process solar table mobile transport is described that moves a solar table to a point of installation. The clamp may be efficiently opened by personnel at the installation point to enable access to a section of the torque tube. |
| FILED | Monday, August 15, 2022 |
| APPL NO | 17/887519 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 25/12 (20180501) Original (OR) Class Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/10 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152835 | Baxter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sustainable Energy Solutions, Inc. (Provo, Utah) |
| ASSIGNEE(S) | Sustainable Energy Solutions, Inc. (Orem, Utah) |
| INVENTOR(S) | Larry Baxter (Orem, Utah); Stephanie Burt (Provo, Utah) |
| ABSTRACT | A method and a system for separating components is disclosed. A process liquid stream, containing a first component and a second component, is passed into an expansion device. The process liquid stream is expanded such that the first component and a first portion of the second component vaporize to form a process vapor stream and a second portion of the second component freezes to form a first solid product stream. The first solid product stream passes out of the expansion device. The process vapor stream passes into a direct-contact heat exchanger against a contact liquid stream. The first portion of the second component desublimates into the contact liquid stream as a second solid product stream. The contact liquid stream and the second solid product stream leave the direct-contact heat exchanger as a slurry stream. The process vapor stream leaves the direct-contact heat exchanger as a stripped process vapor stream. |
| FILED | Tuesday, April 02, 2019 |
| APPL NO | 16/372404 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 1/28 (20130101) B01D 5/006 (20130101) B01D 7/00 (20130101) Liquefaction, Solidification or Separation of Gases or Gaseous Mixtures by Pressure and Cold Treatment F25J 3/0615 (20130101) Original (OR) Class F25J 2205/20 (20130101) F25J 2220/66 (20130101) F25J 2240/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152935 | Shao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Dali Shao (Mechanicville, New York); Shayla Maya Sawyer (Albany, New York); Jie Lian (Niskayuna, New York) |
| ABSTRACT | A hybrid fiber for detection of UV light is described. The hybrid fiber includes a conductor, a first layer, a photoactive layer, a second layer, and a transparent electrode. The conductor includes a conductive material. The first layer includes a first material deposited onto the conductor. The first material is configured to transport holes and block electrons. The photoactive layer includes a photoactive material coating the first layer. The photoactive material includes a first submaterial and a second submaterial. The second layer includes a second material deposited onto the photoactive layer. The second material is configured to block holes and transport electrons. The transparent electrode includes a transparent electrode material deposited onto the second layer. |
| FILED | Tuesday, February 11, 2020 |
| APPL NO | 17/429822 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/429 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/74 (20130101) G01N 2203/0641 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2009 (20130101) H01G 9/2086 (20130101) Organic electric solid-state devices H10K 30/82 (20230201) H10K 30/353 (20230201) H10K 85/30 (20230201) H10K 85/657 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153009 | Horwood et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Corie Horwood (Livermore, California); Michael Stadermann (Pleasanton, California) |
| ABSTRACT | The present disclosure relates to a method for forming a reference electrode for use in electrochemical testing applications. The method may involve positioning a porous frit against one end of a hollow tube, and securing the frit and the hollow tube to one another to form an assembly. The method may further involve forming a silver sulfide coating on a silver wire to produce a silver sulfide coated silver wire. The method may further involve filling the hollow tube with a non-aqueous solution, and inserting at least a portion of the silver sulfide coated silver wire into the non-aqueous solution in the hollow tube. |
| FILED | Wednesday, February 16, 2022 |
| APPL NO | 17/673371 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/0623 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/301 (20130101) Original (OR) Class G01N 27/44704 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154698 | Yacout et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Abdellatif M. Yacout (Naperville, Illinois); Sumit Bhattacharya (Darien, Illinois) |
| ABSTRACT | Fuel pellets can include a fission material powder, a protective layer coated on the fission material powder, and an oxidation diffusion barrier coated on the protective layer, with the protective layer and oxidation diffusion barrier being formed through ALD to achieve infiltration of the coatings within the fuel pellets. |
| FILED | Wednesday, August 05, 2020 |
| APPL NO | 16/986180 |
| ART UNIT | 1718 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/34 (20130101) C23C 16/56 (20130101) C23C 16/45525 (20130101) C23C 16/45555 (20130101) C23C 28/34 (20130101) C23C 28/042 (20130101) Nuclear Reactors G21C 3/20 (20130101) G21C 3/045 (20190101) G21C 3/047 (20190101) G21C 3/626 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/2991 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155048 | Spangenberger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jeffrey S. Spangenberger (Naperville, Illinois); Bryant J. Polzin (Deerfield, Illinois); Jessica L. Durham (Braidwood, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey S. Spangenberger (Naperville, Illinois); Bryant J. Polzin (Deerfield, Illinois); Jessica L. Durham (Braidwood, Illinois) |
| ABSTRACT | A method for producing clean black mass, anode or cathode for subsequent recycling is provided, the method comprising subjecting an intact battery to a shredding process to produce an aggregate, wherein the smallest particle generated is between 2.5 percent and 40 percent of original battery size. Also provided is a shredder for minimizing aggregation of whole batteries, the shredder comprising a shaft defining a longitudinal axis and a latitudinal axis; and a plurality of teeth disposed on said knives which fit on said shaft at an angle to the latitudinal axis selected from 15 degrees and 45 degrees, wherein the teeth have a first proximal end integrally molded to the shaft and a second free distal end. |
| FILED | Friday, February 19, 2021 |
| APPL NO | 17/180621 |
| ART UNIT | 3725 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Crushing, Pulverising, or Disintegrating in General; Milling Grain B02C 18/08 (20130101) B02C 18/142 (20130101) B02C 18/146 (20130101) B02C 18/182 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155066 | Costantino et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Group14 Technologies, Inc. (Woodinville, Washington) |
| ASSIGNEE(S) | Group14 Technologies, Inc. (Woodinville, Washington) |
| INVENTOR(S) | Henry R. Costantino (Woodinville, Washington); Aaron M. Feaver (Seattle, Washington); Avery J. Sakshaug (Snohomish, Washington); Christopher Timmons (Monroe, Washington) |
| ABSTRACT | Composites of silicon and various porous scaffold materials, such as carbon material comprising micro-, meso- and/or macropores, and methods for manufacturing the same are provided. The compositions find utility in various applications, including electrical energy storage electrodes and devices comprising the same. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/156926 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/34 (20130101) B01J 23/72 (20130101) B01J 23/745 (20130101) B01J 23/755 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/24 (20130101) C23C 16/56 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/06 (20130101) H01G 11/24 (20130101) H01G 11/34 (20130101) H01G 11/38 (20130101) H01G 11/50 (20130101) H01G 11/86 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/364 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/0428 (20130101) H01M 4/587 (20130101) H01M 4/1393 (20130101) H01M 4/1395 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155075 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois); BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY (DeKalb, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois); Board of Trustees of Northern Illinois University (DeKalb, Illinois) |
| INVENTOR(S) | Di-Jia Liu (Elmhurst, Illinois); Dominic Rebollar (New Lenox, Illinois) |
| ABSTRACT | A pyrolyzed MOF catalyst for in the carbon dioxide reduction reaction and methods of making the catalyst. The catalysts are composed of highly porous transition metal organic frameworks exhibiting large pores with regular distribution of transition metals within the structure. |
| FILED | Friday, March 12, 2021 |
| APPL NO | 17/200102 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/1691 (20130101) B01J 37/086 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/25 (20210101) C25B 11/095 (20210101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/90 (20130101) H01M 4/9041 (20130101) Original (OR) Class H01M 4/9083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155102 | Edmundson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | W. L. Gore and Associates, Inc. (Newark, Delaware) |
| ASSIGNEE(S) | W. L. Gore and Associates, Inc. (, None) |
| INVENTOR(S) | Mark Edmundson (Rancho Palos Verdes, California); F. Colin Busby (Newark, Delaware) |
| ABSTRACT | Methods and compositions for making fuel cell components are described. In one embodiment, the method comprises providing a substrate, and forming or adhering an electrode on the substrate, wherein the forming includes depositing an aqueous mixture comprising water, a water-insoluble component, a catalyst, and an ionomer. The water-insoluble component comprises a water-insoluble alcohol, a water-insoluble carboxylic acid, or a combination thereof. The use of such water-insoluble components results in a stable liquid medium with reduced reticulation upon drying, reduced dissolution of the substrate, and reduced penetration of the pores of the substrate. |
| FILED | Monday, January 03, 2022 |
| APPL NO | 17/567471 |
| ART UNIT | 1759 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/881 (20130101) H01M 4/926 (20130101) H01M 4/8807 (20130101) H01M 4/8814 (20130101) H01M 4/8828 (20130101) H01M 4/9083 (20130101) H01M 8/1004 (20130101) Original (OR) Class H01M 2008/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155215 | Chinthavali et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Madhu Sudhan Chinthavali (Oak Ridge, Tennessee); Michael Starke (Oak Ridge, Tennessee); Radha Krishna Moorthy (Oak Ridge, Tennessee); Steven Campbell (Oak Ridge, Tennessee) |
| ABSTRACT | A hierarchical approach is provided to integrate functions and components into the various systems and subsystems within a distribution network, including standardization of modular and scalable power electronics power blocks with embedded diagnostics and prognostics. |
| FILED | Thursday, November 17, 2022 |
| APPL NO | 17/989379 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Boards, Substations, or Switching Arrangements for the Supply or Distribution of Electric Power H02B 1/00 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 1/14 (20130101) H02J 1/084 (20200101) H02J 3/06 (20130101) H02J 3/16 (20130101) H02J 3/381 (20130101) Original (OR) Class H02J 2203/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12151000 | Green et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Jordan J. Green (Baltimore, Maryland); Stephany Yi Tzeng (Baltimore, Maryland); Kelly Rhodes (Baltimore, Maryland); Giorgio Raimondi (Baltimore, Maryland); Marcos Iglesias Lozano (Baltimore, Maryland); Jamie Spangler (Baltimore, Maryland); Jakub Tomala (Baltimore, Maryland); Derek VanDyke (Baltimore, Maryland); Randall A. Meyer (Baltimore, Maryland) |
| ABSTRACT | The disclosure is directed to a biodegradable particle comprising a polyester or polyester blend, a first protein that binds to an immune cell, and a second protein that promotes proliferation and/or activation of immune cells, and a third soluble protein or small molecule encapsulated within the particle. The second protein is a fusion protein comprising at least a portion of an antibody and at least a portion of a cytokine (i.e., an immunocytokine). The disclosure also is directed to methods for treating a disease or condition in a subject (e.g., an autoimmune disease) comprising administering the aforementioned biodegradable particle to the subject. |
| FILED | Monday, April 13, 2020 |
| APPL NO | 17/602856 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5031 (20130101) A61K 31/436 (20130101) A61K 47/62 (20170801) A61K 47/6813 (20170801) A61K 47/6845 (20170801) A61K 47/6849 (20170801) A61K 47/6937 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151103 | Shah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Nishal Pradeepkumar Shah (Stanford, California); Eduardo Jose Chichilnisky (Stanford, California) |
| ABSTRACT | Systems and methods for artificial sight in accordance with embodiments of the invention are illustrated. One embodiment includes a retinal prosthesis system including an external controller, a scene imager, an eye imager, an implanted controller, and a stimulation interface in communication with the implanted controller, where the stimulation interface is positioned to stimulate a plurality of retinal ganglion cells (RGCs) of the eye, where the external controller is configured to obtain image data describing a scene from the scene imager, obtain eye position data from the eye imager, determine a field of view (FOV) in the scene based on the eye position data; where the implanted controller is configured to obtain the FOV from the external controller, continuously select stimulation pulses from a dictionary based on the FOV, and stimulate the plurality of RGCs using the stimulation interface in accordance with the selected stimulation pulses. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 17/441261 |
| ART UNIT | 3796 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) A61N 1/025 (20130101) A61N 1/0543 (20130101) A61N 1/36046 (20130101) Original (OR) Class A61N 1/37235 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151271 | Campanella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts) |
| ABSTRACT | Techniques are provided for controlling extraction of landfill gas from a landfill. The techniques include obtaining a measure of pressure in the gas extraction system upstream of a flow control mechanism, wherein the measure of pressure is obtained at a point between at least one well and the at least one flow control mechanism. Further, at least one processor may be used to determine that the measure of pressure in the gas extraction system relative to a measure of atmospheric pressure outside of the gas extraction system is not negative. In response to determining that the measure of pressure in the gas extraction system relative to the measure of atmospheric pressure is not negative, the flow rate of landfill gas being extracted from the at least one well is adjusted using the at least one flow control mechanism to achieve a negative pressure in the gas extraction system. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/168983 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151376 | Cao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Yuanzhi Cao (West Lafayette, Indiana); Karthik Ramani (West Lafayette, Indiana); Zhuangying Xu (Redmond, Washington) |
| ABSTRACT | Disclosed is a visual and spatial programming system for robot navigation and robot-IoT task authoring. Programmable mobile robots serve as binding agents to link stationary IoT devices and perform collaborative tasks. Three key elements of robot task planning (human-robot-IoT) are coherently connected with one single smartphone device. Users can perform visual task authoring in an analogous manner to the real tasks that they would like the robot to perform with using an augmented reality interface. The mobile device mediates interactions between the user, robot(s), and IoT device-oriented tasks, guiding the path planning execution with Simultaneous Localization and Mapping (SLAM) to enable robust room-scale navigation and interactive task authoring. |
| FILED | Tuesday, April 23, 2019 |
| APPL NO | 17/050320 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1661 (20130101) Original (OR) Class B25J 9/1664 (20130101) B25J 9/1689 (20130101) B25J 13/089 (20130101) B25J 19/023 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0038 (20130101) G05D 1/0044 (20130101) G05D 1/223 (20240101) G05D 1/225 (20240101) G05D 1/246 (20240101) G05D 1/0251 (20130101) G05D 1/0274 (20130101) G05D 1/2465 (20240101) Electric Digital Data Processing G06F 3/0486 (20130101) G06F 3/04847 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151938 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wenzhi Li (Miami, Florida); Arun Thapa (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Wenzhi Li (Miami, Florida); Arun Thapa (Miami, Florida) |
| ABSTRACT | Copper-filled carbon nanotubes and methods of synthesizing the same are provided. Plasma-enhanced chemical vapor deposition can be used to synthesize vertically aligned carbon nanotubes filled with copper nanowires. The copper filling can occur concurrently with the carbon nanotube growth, and the carbon nanotubes can be completely filled by copper. The filling of Cu inside the CNTs can be controlled by tuning the synthesis temperature. |
| FILED | Monday, March 15, 2021 |
| APPL NO | 17/201464 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/16 (20170801) Original (OR) Class C01B 32/178 (20170801) C01B 2202/08 (20130101) C01B 2202/10 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/82 (20130101) C01P 2002/85 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/26 (20130101) C23C 16/50 (20130101) C23C 16/0227 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12151978 | Hopkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); Heavy Metal LLC (Fremont, California) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey); Heavy Metal LLC (Fremont, California) |
| INVENTOR(S) | Adam Bayne Hopkins (San Jose, California); Salvatore Torquato (Princeton, New Jersey) |
| ABSTRACT | The present invention relates to granular composite density enhancement, and related methods and compositions. The applications where these properties are valuable include but are not limited to: 1) additive manufacturing (“3D printing”) involving metallic, ceramic, cermet, polymer, plastic, or other dry or solvent-suspended powders or gels, 2) concrete materials, 3) solid propellant materials, 4) cermet materials, 5) granular armors, 6) glass-metal and glass-plastic mixtures, and 7) ceramics comprising (or manufactured using) granular composites. |
| FILED | Wednesday, June 22, 2022 |
| APPL NO | 17/846300 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/052 (20220101) B22F 1/065 (20220101) B22F 3/11 (20130101) B22F 7/002 (20130101) B22F 7/02 (20130101) B22F 7/008 (20130101) B22F 10/28 (20210101) B22F 10/28 (20210101) B22F 10/34 (20210101) B22F 10/34 (20210101) B22F 2202/01 (20130101) B22F 2301/15 (20130101) B22F 2301/35 (20130101) B22F 2301/205 (20130101) B22F 2302/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/342 (20151001) B23K 26/354 (20151001) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 45/0001 (20130101) B29C 64/153 (20170801) B29C 64/165 (20170801) B29C 64/268 (20170801) B29C 64/371 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/0064 (20130101) B29K 2105/251 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 40/00 (20141201) B33Y 70/00 (20141201) B33Y 70/10 (20200101) Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/04 (20130101) C03C 12/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/06 (20130101) C04B 14/06 (20130101) C04B 14/048 (20130101) C04B 20/0076 (20130101) C04B 20/0096 (20130101) C04B 28/02 (20130101) C04B 28/02 (20130101) C04B 35/56 (20130101) C04B 35/111 (20130101) Original (OR) Class C04B 35/547 (20130101) C04B 35/5626 (20130101) C04B 35/62695 (20130101) C04B 2235/405 (20130101) C04B 2235/446 (20130101) C04B 2235/528 (20130101) C04B 2235/608 (20130101) C04B 2235/3217 (20130101) C04B 2235/3847 (20130101) C04B 2235/5427 (20130101) C04B 2235/5436 (20130101) C04B 2235/5445 (20130101) C04B 2235/5472 (20130101) Alloys C22C 1/08 (20130101) C22C 1/0458 (20130101) C22C 14/00 (20130101) C22C 29/08 (20130101) C22C 32/0052 (20130101) C22C 38/002 (20130101) C22C 38/02 (20130101) C22C 38/44 (20130101) C22C 38/56 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/25 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152008 | Raghavan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Srivatsan Raghavan (Boston, Massachusetts); Bruce Kuan-Yee Hua (Cambridge, Massachusetts); Shubhroz Gill (Cambridge, Massachusetts); Stuart Schreiber (Cambridge, Massachusetts); William Hahn (Boston, Massachusetts); Paul Clemons (Cambridge, Massachusetts); Raymond Ng (Boston, Massachusetts); Partha Nag (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are compounds useful for the treatment of various proliferative diseases. These compounds, as well as pharmaceutically acceptable salts thereof may be formulated in pharmaceutical compositions, and may be used in methods of treatment and/or prophylaxis of proliferative diseases, including cancer, and more specifically, pancreatic cancer. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/013269 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0043 (20130101) A61K 9/0053 (20130101) Heterocyclic Compounds C07D 233/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152239 | Nelles |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tacit Therapeutics, Inc. (South San Francisco, California) |
| ASSIGNEE(S) | Tacit Therapeutics, Inc. (South San Francisco, California) |
| INVENTOR(S) | David A. Nelles (San Francisco, California) |
| ABSTRACT | Disclosed are methods and compositions for promoting trans-splicing. In some embodiments, the composition comprises an engineered small nuclear RNA that promotes trans-splicing of a target RNA molecule. The composition may further comprise an RNA donor molecule. |
| FILED | Monday, July 31, 2023 |
| APPL NO | 18/362698 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) Original (OR) Class C12N 2320/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152910 | Evke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Erin Evke (Ann Arbor, Michigan); Eugene Shteyn (Ann Arbor, Michigan); Max Shtein (Ann Arbor, Michigan) |
| ABSTRACT | A sensor device includes a substrate having a plurality of cuts through the substrate to define a set of substrate sections, the substrate being flexible, and a plurality of sensor structures supported by the substrate, each sensor structure of the plurality of sensor structures being disposed at a respective substrate section of the set of substrate sections. Deformation of the substrate deforms each respective substrate section of the set of substrate sections such that each respective substrate section is deformed to a respective extent. Each sensor structure of the plurality of sensor structures is configured to provide an indication of the respective extent of the deformation. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 17/294172 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 11/30 (20130101) Original (OR) Class Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152988 | Kelley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| INVENTOR(S) | Mathew L. Kelley (Columbia, South Carolina); Andrew B. Greytak (Columbia, South Carolina); M V S Chandrashekhar (Columbia, South Carolina) |
| ABSTRACT | Spatially resolved Fourier Transform Impedance Spectroscopy (FTIS) is disclosed to spatially map and quickly build the frequency response of optoelectronic devices using optical probes. The transfer function of a linear system is the Fourier transform of its impulse response, which may be obtained from transient photocurrent measurements of devices such as photodetectors and solar cells. We apply FTIS to a PbS colloidal quantum dot (QD)/SiC heterojunction photodiode and corroborate results using intensity-modulated photocurrent spectroscopy. The cutoff frequencies of the QD/SiC devices were as high as ˜10 kHz, demonstrating their utility in advanced flexible and thin film electronics. The practical frequencies for FTIS lie in the mHz-kHz range, ideal for composite or novel materials such as QD films that are dominated by interfacial trap states. |
| FILED | Monday, March 07, 2022 |
| APPL NO | 17/688230 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6452 (20130101) Original (OR) Class G01N 21/6456 (20130101) G01N 2021/6423 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153044 | Halpern et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of New Hampshire (Durham, New Hampshire); University of New England (Biddeford, Maine) |
| ASSIGNEE(S) | University of New England (Biddeford, Maine); University of New Hampshire (Durham, New Hampshire) |
| INVENTOR(S) | Jeffrey M. Halpern (Durham, New Hampshire); Eva Rose M. Balog (Biddeford, Maine) |
| ABSTRACT | 2-dimensional surfaces modified with elastin-like polymer (ELP) that transitions between states in the presence of one or more analytes are described. This transition can be monitored to identify the presence and concentration of the one or more analytes. 2-dimensional surfaces of the present disclosure may also or alternatively be configured such that when an analyte binds to ELP on the 2-dimensional surface, such binding changes a degree at which the ELP responds to various non-analyte stimuli (e.g., pH, temperature, etc.). In such examples, the 2-dimensional surface may detect the presence of analyte based on the how the ELP responds to the non-analyte stimuli. For example, ELP on a 2-dimensional surface may transition between states at a first temperature when analyte is not present (e.g., bound to the ELP). The temperature at which the ELP transitions may change based on how much analyte (e.g., what concentration of analyte) is present. |
| FILED | Wednesday, October 30, 2019 |
| APPL NO | 16/668858 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/026 (20130101) G01N 27/48 (20130101) G01N 27/3276 (20130101) G01N 33/54313 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153227 | Maddox et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Mizar Imaging, LLC (Woods Hole, Massachusetts) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina); MIZAR IMAGING, LLC (Woods Hole, Massachusetts) |
| INVENTOR(S) | Paul Samuel Maddox (Chapel Hill, North Carolina); Tanner Christian Fadero (Chapel Hill, North Carolina); Joel Carter Smith (East Falmouth, Massachusetts) |
| ABSTRACT | Methods for imaging a sample using fluorescence microscopy, systems for imaging a sample using fluorescence microscopy, and illumination systems for fluorescence microscopes. In some examples, a method includes positioning the sample such that a plane of interest of the sample is coplanar with a focal plane of a detection objective of a microscope; positioning a mirror around the sample; directing a beam of annularly collimated excitation light on the mirror to focus a disc of light on the sample; and imaging the sample through the detection objective. |
| FILED | Wednesday, April 20, 2022 |
| APPL NO | 17/725501 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 2021/6463 (20130101) Optical Elements, Systems, or Apparatus G02B 21/02 (20130101) G02B 21/08 (20130101) G02B 27/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153448 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the Nevada System of Higher Education on Behalf of the University of Nevada (Las Vegas, Nevada) |
| ASSIGNEE(S) | The Board of Regents of the Nevada System of Higher Education on Behalf of the University of Nevada (Las Vegas, Nevada) |
| INVENTOR(S) | Dongbin Kim (Las Vegas, Nevada); Paul Y. Oh (Las Vegas, Nevada) |
| ABSTRACT | A parallel manipulator with six degrees of freedom may include a base that attaches to a unmanned aerial vehicle and a movable gripper element that may be positioned below the UAV. The positioning of the gripper element my reduce impact of the center of gravity of the attached UAV. The gripper element may include a geometric shape that complements objects routinely used in high-throughput screening (HTS) laboratories, such as microplates. The parallel manipulator and gripper element may be used to quickly, safely, and securely move objects in HTS laboratories and/or the like. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 17/348453 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 5/00 (20130101) B25J 9/003 (20130101) B25J 13/081 (20130101) B25J 13/089 (20130101) B25J 15/0052 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/22 (20130101) Unmanned aerial vehicles [UAV]; equipment therefor B64U 60/00 (20230101) B64U 2101/64 (20230101) Systems for Controlling or Regulating Non-electric Variables G05D 1/106 (20190501) Original (OR) Class G05D 1/0816 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153737 | Ramani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Karthik Ramani (West Lafayette, Indiana); Tianyi Wang (West Lafayette, Indiana); Xun Qian (West Lafayette, Indiana); Fengming He (West Lafayette, Indiana) |
| ABSTRACT | An augmented reality (AR) application authoring system is disclosed. The AR application authoring system enables the real-time creation of freehand interactive AR applications with freehand inputs. The AR application authoring system enables intuitive authoring of customized freehand gesture inputs through embodied demonstration while using the surrounding environment as a contextual reference. A visual programming interface is provided with which users can define freehand interactions by matching the freehand gestures with reactions of virtual AR assets. Thus, users can create personalized freehand interactions through simple trigger-action programming logic. Further, with the support of a real-time hand gesture detection algorithm, users can seamlessly test and iterate on the authored AR experience. |
| FILED | Tuesday, July 26, 2022 |
| APPL NO | 17/814965 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/017 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 13/20 (20130101) G06T 19/006 (20130101) G06T 2200/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12153944 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shih-Wei Li (New York, New York); Jason Nieh (New York, New York); John S. Koh (Ridgefield, New Jersey) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Shih-Wei Li (New York, New York); Jason Nieh (New York, New York); John S. Koh (Ridgefield, New Jersey) |
| ABSTRACT | Systems comprising: a memory; and a hardware processor and configured to: execute a hypervisor having a first portion and a second portion, wherein the first portion of the hypervisor executes at a first exception level that allows the first portion to access data of a virtual machine in the hardware processor and the memory, and wherein the second portion of the hypervisor executes at a second exception level that prevents the second portion from accessing the data of the virtual machine in the hardware processor and the memory. Methods comprising: executing a first portion of a hypervisor at a first exception level that allows the first portion to access data of a virtual machine in a hardware processor and memory; and executing a second portion of a hypervisor at a second exception level that prevents the second portion from accessing the data in the hardware processor and the memory. |
| FILED | Monday, June 29, 2020 |
| APPL NO | 16/916051 |
| ART UNIT | 2199 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4401 (20130101) G06F 9/5077 (20130101) G06F 9/45558 (20130101) Original (OR) Class G06F 21/44 (20130101) G06F 2009/45587 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154322 | Adjouadi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Malek Adjouadi (Miami, Florida); Mohammad Eslami (Miami, Florida); Solale Tabarestani (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board Of Trustees (Miami, Florida) |
| INVENTOR(S) | Malek Adjouadi (Miami, Florida); Mohammad Eslami (Miami, Florida); Solale Tabarestani (Miami, Florida) |
| ABSTRACT | Systems and methods are provided for color-coded visualization to aid in diagnosis and prognosis of Alzheimer's disease (AD). The color-coded visualization mechanism can be driven by an integrated machine learning (ML) model, which can take as its inputs neuroimaging (e.g., magnetic resonance imaging (MRI), positron emission tomography (PET)) data, neuropsychological test scores, the cerebrospinal fluid (CSF) biomarker, and/or risk factors. With these inputs, the ML model can generate a color-coded visualization of the disease state. |
| FILED | Tuesday, March 12, 2024 |
| APPL NO | 18/602673 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4088 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) G06T 11/001 (20130101) G06T 2207/10024 (20130101) G06T 2207/10088 (20130101) G06T 2207/10104 (20130101) G06T 2207/30016 (20130101) G06T 2207/30204 (20130101) Image or Video Recognition or Understanding G06V 10/811 (20220101) Original (OR) Class G06V 10/7715 (20220101) G06V 2201/03 (20220101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155519 | Walk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); MOXZ GmbH (Berlin, Germany) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); MOXZ GmbH (Berlin, Germany) |
| INVENTOR(S) | Philipp Walk (Pasadena, California); Babak Hassibi (San Marino, California); Peter Jung (Berlin, Germany) |
| ABSTRACT | Systems and methods for transmitting data using various Modulation on Zeros schemes are described. In many embodiments, a communication system is utilized that includes a transmitter having a modulator that modulates a plurality of information bits to encode the bits in the zeros of the z-transform of a discrete-time baseband signal. In addition, the communication system includes a receiver having a decoder configured to decode a plurality of bits of information from the samples of a received signal by: determining a plurality of zeros of a z-transform of a received discrete-time baseband signal based upon samples from a received continuous-time signal, identifying zeros that encode the plurality of information bits, and outputting a plurality of decoded information bits based upon the identified zeros. |
| FILED | Friday, July 21, 2023 |
| APPL NO | 18/357064 |
| ART UNIT | 2635 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Multiplex Communication H04J 11/00 (20130101) H04J 2011/0096 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0204 (20130101) H04L 27/2627 (20130101) Original (OR) Class H04L 27/2639 (20130101) H04L 27/2663 (20130101) H04L 27/26532 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155738 | Yeh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Edmund Meng Yeh (Newton, Massachusetts); Ying Cui (Shaanxi, China PRC); Ran Liu (Heilongjiang, China PRC); Tracey Ho (Pasadena, California); Michael Burd (Lees Summit, Missouri); Derek Leong (Singapore, Singapore) |
| ABSTRACT | A system and method for joint dynamic interest request forwarding and dynamic cache placement and eviction and provided within the context of the Named Data Networking (NDN) architecture. The system and method employ a virtual control plane that operates on the user demand rate for data objects in the network, and an actual plane that handles Interest Packets and Data Packets. Distributed algorithms within the virtual plane achieve network load balancing through dynamic forwarding and caching, thereby maximizing the user demand rate that the NDN network can satisfy. A method of congestion control is also provided to achieve optimal network fairness using the VIP framework. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/683931 |
| ART UNIT | 2449 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/02 (20130101) H04L 45/64 (20130101) H04L 45/586 (20130101) H04L 47/27 (20130101) H04L 67/568 (20220501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12152628 | Rice et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornerstone Research Group, Inc. (Miamisburg, Ohio) |
| ASSIGNEE(S) | Cornerstone Research Group, Inc. (Miamisburg, Ohio) |
| INVENTOR(S) | Jason Rice (Dayton, Ohio); Mark Cridge (Miamisburg, Ohio); Trang Young (Dayton, Ohio); Brian Pleiman (Dayton, Ohio); Kory Evanson (Vandalia, Ohio); Jason Hermiller (Lebanon, Ohio) |
| ABSTRACT | A reversible joint includes male and female components. The male component has a rigid stud with a shaft region and a head region having a greater width, than the shaft region. The female component includes a polymer-based bushing including a polymer sleeve and an embedded heating element. The polymer sleeve is formed from a shape memory polymer (SMP) or an SMP composite and includes a central channel. The polymer-based bushing is capable of being activated by heating with the embedded heating element to reversibly render the polymer sleeve elastic and allow deformation of the central channel to an expanded channel width during insertion of the head region. The polymer sleeve becomes rigid after deactivation of the polymer-based bushing for retention of the male component. Load bearing assemblies formed by connecting modular structures with the reversible joint are also provided along with installation tools for the same. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/061653 |
| ART UNIT | 3678 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/64 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 7/0413 (20130101) Original (OR) Class F16B 2200/77 (20230801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154773 | Cooks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Dalton Snyder (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to systems and methods for collision induced dissociation of ions in an ion trap. In certain aspects, the invention provides a system that includes a mass spectrometer having an ion trap, and a central processing unit (CPU). The CPU includes storage coupled to the CPU for storing instructions that when executed by the CPU cause the system to generate one or more signals, and apply the one or more signals to the ion trap in a manner that all ions within the ion trap are fragmented at a same Mathieu q value. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144394 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/0027 (20130101) H01J 49/0031 (20130101) Original (OR) Class H01J 49/0045 (20130101) H01J 49/0068 (20130101) H01J 49/427 (20130101) H01J 49/4295 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12155392 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Hao Wang (Davis, California); Omeed Momeni (Davis, California) |
| ABSTRACT | The disclosed embodiments provide various compensated charge pumps (CPs) which have a current mismatch compensation circuitry and various CP output-current-mismatch compensation structures based on using a dummy charge pump (CPdum) and feedback loops. In some embodiments, the CPdum is identically biased as the CP to be compensated. CPdum is configured to sense the output voltage and use the feedback loops to generate compensation currents for the CP. The compensation currents simultaneously compensate CP and CPdum. Moreover, CPdum is loaded with high impedance so that the compensation current makes sure CPdum doesn't have current mismatch. Because CP and CPdum have identical biasings and are compensated in the same manner with the same amount of current, CP output current mismatch is hence effectively eliminated. |
| FILED | Thursday, October 14, 2021 |
| APPL NO | 18/247240 |
| ART UNIT | 2849 — Electrical Circuits and Systems |
| CURRENT CPC | Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/091 (20130101) H03L 7/0891 (20130101) Original (OR) Class H03L 2207/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 12152889 | Tenzer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Novateur Research Solutions (Ashburn, Virginia) |
| ASSIGNEE(S) | Novateur Research Solution (Ashburn, Virginia) |
| INVENTOR(S) | Mark Tenzer (Ashburn, Virginia); Emmanuel Tung (Ashburn, Virginia); Khurram Hassan-Shafique (Ashburn, Virginia); Zeeshan Rasheed (Ashburn, Virginia) |
| ABSTRACT | Generating trajectories from an implicit neural representation (INR) model to predict human mobility in uncertain traffic conditions includes receiving geocoordinate data representing vehicle motion observations of a traffic pattern; receiving a road network based on the geocoordinate data; training the INR model to learn continuous, latent fields of stochastic traffic properties over space and time based on the geocoordinate data; utilizing the INR model to extract spatio-temporal speed distributions from the geocoordinate data; applying a near-shortest-path, heuristic algorithm, weighted by predictions of the INR model, to produce real-world routing choices for traversing the road network; generating trajectories for transportation between an origin and destination in the road network using the algorithm and the predictions of the INR model, wherein the trajectories reflect non-deterministic and diverse route choices in the road network; and outputting generated trajectories to improve routing choices for a GPS and to provide the route choices for selection. |
| FILED | Thursday, December 07, 2023 |
| APPL NO | 18/532557 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/3446 (20130101) Original (OR) Class G01C 21/3492 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154717 | Chu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | THE MITRE CORPORATION (McLean, Virginia) |
| INVENTOR(S) | Alejandro Chu (Madison, Alabama) |
| ABSTRACT | Fabricating composite monolithic structures to achieve optimal electrical, thermal, and mechanical properties through the elimination of air is discussed herein. A method of fabricating a composite structure includes coating an insulating layer with an uncured binding material and performing a first curing process on the uncured binding material to form a first stage cured binding material on the insulating layer without introduction of air pockets in a conventional manufacturing atmospheric environment. The method further includes disposing the insulating layer on an array of conductive structures. The first stage cured binding material is positioned between the insulating layer and the array of conductive structures. The method further includes performing a second curing process on the first stage cured binding material to form a cured binding material, and forming cured regions between adjacent conductive structures of the array of conductive structures. |
| FILED | Tuesday, August 11, 2020 |
| APPL NO | 16/990408 |
| ART UNIT | 2837 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 5/06 (20130101) Original (OR) Class H01F 19/00 (20130101) H01F 27/288 (20130101) H01F 27/323 (20130101) H01F 41/122 (20130101) H01F 41/125 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 12154003 | Inoue et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Ken Inoue (Elmsford, New York); Maika Takita (Croton-on-Hudson, New York); Antonio Corcoles-Gonzalez (Mount Kisco, New York); Scott Douglas Lekuch (New York, New York) |
| ABSTRACT | Systems, computer-implemented methods, and computer program products that can facilitate determining a state of a qubit are described. According to an embodiment, a system can comprise a memory that stores computer executable components and a processor that executes the computer executable components stored in the memory. The computer executable components can comprise an output receiving component that can receive, in response to a request, output representative of a quantum state of a qubit of a quantum computing device, and a classifying component that classifies the quantum state of the qubit of the quantum computing device based on the output representative of the quantum state of the qubit. The system can further include a configuring component that can configure the classifying component based on a characteristic of the request. |
| FILED | Tuesday, March 14, 2023 |
| APPL NO | 18/183602 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) G06F 18/2411 (20230101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class G06N 10/20 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12154005 | Monroe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| INVENTOR(S) | Christopher Monroe (Ellicott City, Maryland); Marko Cetina (College Park, Maryland); Norbert Linke (Stevenson, Maryland); Shantanu Debnath (College Park, Maryland) |
| ABSTRACT | The disclosure describes various aspects of optical control of atomic quantum bits (qubits) for phase control operations. More specifically, the disclosure describes methods for coherently controlling quantum phases on atomic qubits mediated by optical control fields, applying to quantum logic gates, and generalized interactions between qubits. Various attributes and settings of optical/qubit interactions (e.g., atomic energy structure, laser beam geometry, polarization, spectrum, phase, background magnetic field) are identified for imprinting and storing phase in qubits. The disclosure further describes how these control attributes are best matched in order to control and stabilize qubit interactions and allow extended phase-stable quantum gate sequences. |
| FILED | Monday, April 24, 2023 |
| APPL NO | 18/305954 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Optical Computing Devices; G06E 1/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 12151271 | Campanella et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Andrew Campanella (Somerville, Massachusetts); Joseph G. Michels (New York, New York); Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts) |
| ABSTRACT | Techniques are provided for controlling extraction of landfill gas from a landfill. The techniques include obtaining a measure of pressure in the gas extraction system upstream of a flow control mechanism, wherein the measure of pressure is obtained at a point between at least one well and the at least one flow control mechanism. Further, at least one processor may be used to determine that the measure of pressure in the gas extraction system relative to a measure of atmospheric pressure outside of the gas extraction system is not negative. In response to determining that the measure of pressure in the gas extraction system relative to the measure of atmospheric pressure is not negative, the flow rate of landfill gas being extracted from the at least one well is adjusted using the at least one flow control mechanism to achieve a negative pressure in the gas extraction system. |
| FILED | Tuesday, February 14, 2023 |
| APPL NO | 18/168983 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12152163 | Monickam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PIXELLIGENT TECHNOLOGIES LLC (Baltimore, Maryland) |
| ASSIGNEE(S) | PIXELLIGENT TECHNOLOGIES LLC (Baltimore, Maryland) |
| INVENTOR(S) | Selina Monickam (Takoma Park, Maryland); Darryl Peters (, None); Gregory Cooper (Fulton, Maryland); Zhiyun Chen (Olney, Maryland); Robert Swisher (Baltimore, Maryland) |
| ABSTRACT | The present disclosure provides a high refractive index acrylic formulation embedded with sub-10 nm metal oxide nanocrystals. The formulation is ideal for high refractive index, high transparency coating for a variety of optical applications including OLED lighting. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/321289 |
| ART UNIT | 1783 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 3/22 (20130101) C08K 9/04 (20130101) C08K 9/06 (20130101) C08K 2003/2244 (20130101) C08K 2201/011 (20130101) Compositions of Macromolecular Compounds C08L 33/06 (20130101) C08L 33/10 (20130101) C08L 33/10 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/004 (20130101) Original (OR) Class C09D 7/20 (20180101) C09D 7/62 (20180101) C09D 7/67 (20180101) C09D 11/033 (20130101) C09D 11/037 (20130101) C09D 11/101 (20130101) C09D 11/107 (20130101) C09D 135/02 (20130101) Optical Elements, Systems, or Apparatus G02B 1/111 (20130101) Organic electric solid-state devices H10K 50/854 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 12151862 | Liceaga et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Andrea M. Liceaga (West Lafayette, Indiana); Uriel Urbizo-Reyes (West Lafayette, Indiana) |
| ABSTRACT | The present application relates generally to a process of manufacturing an optimized packing material comprising chia seed mucilage (CSM), glycerol, and sorbitol, wherein said packaging materials have a good tensile strength (2.005 N/mm2), lower water vapor permeability (1.73×10−9 g×s×Pa/m), a good flexibility (e.g. high elongation at break, 31.729%). The optimum conditions of polyol concentration were 1.3 g of glycerol and 2.0 g of sorbitol per g of CSM. Based on these results, chia seed mucilage can successfully be used to develop biofilms with potential to be used in drug delivery and edible food coating applications. Both the process and the products are within the scope of this application. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 17/529386 |
| ART UNIT | 1782 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 29/238 (20160801) Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 65/02 (20130101) Original (OR) Class B65D 65/466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 12152296 | Dunand et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | David C. Dunand (Evanston, Illinois); Fernando Reyes Tirado (Evanston, Illinois) |
| ABSTRACT | A cobalt based superalloy and a method of producing the same. The superalloy includes a nominal composition comprising at least cobalt, aluminum, Z and vanadium, Z being at least one of tantalum and niobium, processed such that the superalloy comprises gamma and gamma-prime phases with stable gamma+gamma-prime microstructures. |
| FILED | Wednesday, May 22, 2019 |
| APPL NO | 17/056519 |
| ART UNIT | 1738 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Alloys C22C 19/07 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 12150777 | Etkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); Board of Regents, The University of Texas System (Austin, Texas); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Amit Etkin (Palo Alto, California); Yu Zhang (Palo Alto, California); Greg Fonzo (Palo Alto, California); Madhukar Trivedi (Palo Alto, California) |
| ABSTRACT | Provided herein are, inter alia, methods for identifying subjects suffering from depression that will respond to treatment with an antidepressant. |
| FILED | Friday, March 15, 2019 |
| APPL NO | 16/981822 |
| ART UNIT | 3798 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0075 (20130101) A61B 5/165 (20130101) A61B 5/316 (20210101) A61B 5/369 (20210101) A61B 5/4848 (20130101) Original (OR) Class A61B 5/7264 (20130101) A61B 5/7267 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/135 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/20 (20180101) G16H 20/70 (20180101) G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 12153628 | Burkhardt |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States as represented by the Director, National Security Agency (Ft. George G. Meade, Maryland) |
| ASSIGNEE(S) | The Government of the United States as represented by the Director, National Security Agency (Ft. George G. Meade, Maryland) |
| INVENTOR(S) | Paul Burkhardt (North Potomac, Maryland) |
| ABSTRACT | Methods of measuring graph triangle centrality and for ranking the nodes of a graph based upon the graph triangle centrality measure are provided. |
| FILED | Tuesday, November 17, 2020 |
| APPL NO | 17/099986 |
| ART UNIT | 2168 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/906 (20190101) G06F 16/9024 (20190101) Original (OR) Class G06F 17/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 12154066 | Dixon, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Robert E. Dixon, Jr. (Haymarket, Virginia); Gary C. Reblin (Falls Church, Virginia); Naomi Miller (Washington, District of Columbia) |
| ABSTRACT | Systems and methods for delivering items are disclosed. The systems and methods comprise assigning a unique internal control value to each profile having an identified physical address delivery point. They also receive a request for delivery point information for each of a plurality of items to be distributed and providing a response comprising a list of internal control values thereto. They further receive a plurality of items, each item having printed thereon one of the internal control values on the list. For each of the plurality of items, they scan, by item processing equipment, the item to read the internal control value printed thereon, identifying, in the profile database, the physical address delivery point corresponding to the assigned internal control value, routing, by the item processing equipment, the item according to the identified physical address delivery point, and delivering the item to the identified physical address delivery point. |
| FILED | Wednesday, June 28, 2023 |
| APPL NO | 18/343328 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) G06K 19/06028 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/083 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 12151813 | Budd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sky Launch Corporation (Lancaster, California) |
| ASSIGNEE(S) | Sky Launch Corporation (Lancaster, California) |
| INVENTOR(S) | Gerald D. Budd (Lancaster, California); Charles E. Rogers (Lancaster, California) |
| ABSTRACT | A system and method for carrying an aeronautical or launch vehicle to altitude for release to flight may involve a multiplicity of mounting elements affixed to a carrier aircraft in distributed fashion along a mounting axis. Each mounting element may include a cradle and a retention strap. Each retention strap may be suspendedly attached to a respective cradle, and actuatable from a retention configuration to a release configuration. The retention configuration allows the retention straps to clampingly secure the vehicle to the respective cradles. The actuation of the retention straps from the retention configuration to the release configuration may disable the clamping securement and thereby release the vehicle to drop away from the cradles. For one or more of the retention straps, the actuation may be by way of detonating at least one corresponding pyrotechnic fastener. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/372388 |
| ART UNIT | 3619 — Electrical Circuits and Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 1/02 (20130101) Original (OR) Class B64D 5/00 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/005 (20130101) Unmanned aerial vehicles [UAV]; equipment therefor B64U 70/20 (20230101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 3/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 26, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20241126.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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