FedInvent™ Patents
Patent Details for Tuesday, December 03, 2024
This page was updated on Monday, December 09, 2024 at 06:57 PM GMT
Department of Health and Human Services (HHS)
| US 12156517 | Wiles et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | Michael V. Wiles (Bar Harbor, Maine); Derry C. Roopenian (Bar Harbor, Maine); Greg Christianson (Bar Harbor, Maine); Benjamin E. Low (Bar Harbor, Maine) |
| ABSTRACT | The present disclosure provides improved humanized IgG1 FCRN mouse models for use, for example, in estimating serum half-life of therapeutic proteins such as monoclonal antibodies. |
| FILED | Friday, February 25, 2022 |
| APPL NO | 17/680379 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0278 (20130101) Original (OR) Class A01K 2207/15 (20130101) A01K 2227/105 (20130101) Peptides C07K 14/70535 (20130101) C07K 16/283 (20130101) C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/52 (20130101) C07K 2317/72 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156696 | Klin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| ASSIGNEE(S) | Children's Healthcare of Atlanta, Inc. (Atlanta, Georgia) |
| INVENTOR(S) | Ami Klin (Atlanta, Georgia); Warren Jones (Decatur, Georgia) |
| ABSTRACT | Systems, devices, and methods are described for assessing the risk of developmental, cognitive, social, or mental abilities or disabilities in very young patients (e.g., in the first 2-6 months of life). Generally, the decline in visual fixation of a subject over time with respect to certain dynamic stimuli provides a marker of possible abilities or disabilities (such as ASD). The visual fixation of the subject is identified, monitored, and tracked over time through repeated eye tracking sessions, and data relating to the visual fixation is then analyzed to determine a possible increased risk certain conditions in the subject. A change in visual fixation as compared to similar visual fixation data of typically-developing subjects or to a subject's own, prior visual fixation data provides an indication of a developmental, cognitive, or mental ability or disability. |
| FILED | Tuesday, December 19, 2023 |
| APPL NO | 18/545362 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/0025 (20130101) A61B 3/113 (20130101) Original (OR) Class A61B 5/163 (20170801) A61B 5/167 (20130101) A61B 5/168 (20130101) A61B 2503/04 (20130101) A61B 2503/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156708 | Saeidi et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The Johns Hopkins University (Baltimore, Maryland); Children's National Medical Center (Washington, District of Columbia) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); THE JOHN HOPKINS UNIVERSITY (Baltimore, Maryland); CHILDREN'S NATIONAL MEDICAL CENTER (Washington, District of Columbia) |
| INVENTOR(S) | Hamed Saeidi (College Park, Pennsylvania); Axel Krieger (Alexandria, Virginia); Simon Leonard (State College, Pennsylvania); Justin Opfermann (Washington, District of Columbia) |
| ABSTRACT | The present disclosure provides a system and method for controlling an articulating member including a tool. The method includes determining a first confidence indicator based on a manual control mode for the articulating member, determining a second confidence indicator based on an autonomous control mode for the articulating member, generating an allocation function based on the first confidence indicator and the second confidence indicator, and generating a control command for the articulating member based on the allocation function. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 17/054960 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/32 (20130101) A61B 18/14 (20130101) A61B 34/25 (20160201) A61B 34/30 (20160201) Original (OR) Class A61B 34/32 (20160201) A61B 34/74 (20160201) A61B 34/76 (20160201) A61B 2018/00595 (20130101) A61B 2018/1425 (20130101) Manipulators; Chambers Provided With Manipulation Devices B25J 9/1653 (20130101) B25J 9/1689 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156791 | Gannett et al. |
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| APPLICANT(S) | TRICOL BIOMEDICAL, INC. (Portland, Oregon) |
| ASSIGNEE(S) | TRICOL BIOMEDICAL, INC. (Portland, Oregon) |
| INVENTOR(S) | Cole Gannett (Portland, Oregon); Mattie R. Jones (Portland, Oregon); Ervelyn Winata (Portland, Oregon); Simon J. Mccarthy (Portland, Oregon) |
| ABSTRACT | The present invention relates to a biocompatible, foldable, thin profile, low mass and high surface area, chitosan dressing, optionally modified with catechol, and suitable for treating bleeding in a physiological environment, e.g. bladder, and in particular in connection with the TURP procedure. The characteristics and structures of the chitosan dressing are provided. Methods of making and using the chitosan dressing are also provided. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/958307 |
| ART UNIT | 3786 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 13/36 (20130101) Original (OR) Class A61F 13/266 (20130101) A61F 13/2025 (20130101) A61F 13/2071 (20130101) A61F 13/2077 (20130101) A61F 2013/2014 (20130101) A61F 2013/15422 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/28 (20130101) A61L 15/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156877 | Jain et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Isha Jain (San Francisco, California); Xuewen Chen (San Francisco, California) |
| ABSTRACT | The present disclosure provides methods of alleviating a symptom or delaying disease progression of a condition associated with a thiamine deficiency, a thiamine-dependent enzyme, or an associated cofactor and/or treating a condition associated with a thiamine deficiency, a thiamine-dependent enzyme, or an associated cofactor. The present methods result in alleviating a symptom or delaying disease progression of the condition associated with the thiamine deficiency, the thiamine-dependent enzyme, or the associated cofactor, treatment of the condition associated with the thiamine deficiency, the thiamine-dependent enzyme, or the associated cofactor, and/or alteration of a phenotypic characteristic of the condition associated with the thiamine deficiency, the thiamine-dependent enzyme, or the associated cofactor. |
| FILED | Wednesday, January 15, 2020 |
| APPL NO | 16/743836 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/14551 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/51 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156879 | Yan et al. |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Riqiang Yan (Farmington, Connecticut); Brati Das (Farmington, Connecticut) |
| ABSTRACT | Disclosed pharmaceutical compositions including a Beta site APP Cleaving Enzyme (BACE1) inhibitor and an metabotropic glutamate receptor (mGluR) agonist, and methods for use of such compositions to treat Alzheimer's disease (AD), Down's syndrome, Parkinson's disease, vascular dementia, Dementia with Lewy Bodies, dementia, and/or frontal temporal dementia. |
| FILED | Tuesday, December 01, 2020 |
| APPL NO | 17/108227 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) A61K 31/541 (20130101) A61K 31/549 (20130101) Original (OR) Class A61K 31/4439 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156884 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Mei Zhang (Cleveland, Ohio); Alex Y. Huang (Cleveland, Ohio); Julian Kim (Cleveland, Ohio) |
| ABSTRACT | A method of treating a subject having cancer is described that includes administering a therapeutically effective amount of a β-(1,3)-(1,4) glucan to the subject. Methods of immunostimulating in a subject by administering an effective amount of a β-(1,3)-(1,4) glucan to the subject are also described. |
| FILED | Wednesday, February 10, 2021 |
| APPL NO | 17/172150 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/716 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156889 | Shi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Yufang Shi (Belle Mead, New Jersey); Guangwen Ren (Bar Harbor, Maine); Liying Zhang (Belle Mead, New Jersey) |
| ABSTRACT | The present invention provides methods or kits with inflammatory cytokines to pretreat 1-ISCs to augment their immune modulatory effect, in prevention and treatment of various diseases such as multiple sclerosis, arthritis, lupus, sepsis, hepatitis, cirrhosis, Parkinson's disease, chronic infections, and GvHD. The present invention relates to novel methods for enhancing the immunosuppressive or the immune stimulatory activities of mesenchymal stem cells (JvfSCs). |
| FILED | Friday, January 15, 2021 |
| APPL NO | 17/150457 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 35/28 (20130101) A61K 38/20 (20130101) A61K 38/191 (20130101) A61K 38/191 (20130101) A61K 38/212 (20130101) A61K 38/215 (20130101) A61K 38/217 (20130101) A61K 38/217 (20130101) A61K 38/1825 (20130101) A61K 38/1841 (20130101) A61K 38/2006 (20130101) A61K 38/2006 (20130101) A61K 45/06 (20130101) A61K 2035/122 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/02 (20180101) A61P 37/04 (20180101) A61P 37/06 (20180101) Peptides C07K 14/50 (20130101) C07K 14/52 (20130101) C07K 14/56 (20130101) C07K 14/57 (20130101) C07K 14/495 (20130101) C07K 14/525 (20130101) C07K 14/545 (20130101) C07K 14/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0607 (20130101) C12N 5/0662 (20130101) C12N 5/0663 (20130101) C12N 5/0665 (20130101) C12N 2500/05 (20130101) C12N 2501/10 (20130101) C12N 2501/15 (20130101) C12N 2501/24 (20130101) C12N 2501/25 (20130101) C12N 2501/115 (20130101) C12N 2501/2301 (20130101) C12N 2501/2317 (20130101) C12N 2502/1114 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156890 | Hartung et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Thomas Hartung (Baltimore, Maryland); David Pamies (Baltimore, Maryland); Helena T. Hogberg (Nottingham, Maryland) |
| ABSTRACT | The present invention relates to novel compositions and methods to produce 3D organ equivalents of the brain (i.e. “mini-brains”). The invention also relates to methods of using human induced pluripotent stem cells, a combination of growth and other soluble factors and gyratory shaking. Cells from healthy or diseased donors or animals can be used to allow testing different genetic backgrounds. The model can be further enhanced by using genetically modified cells, adding micro-glia or their precursors or indicator cells (e.g. with reporter genes or tracers) as well as adding endothelial cells to form a blood-brain-barrier. |
| FILED | Friday, February 10, 2017 |
| APPL NO | 16/077411 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Original (OR) Class A61K 38/41 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0696 (20130101) C12N 2501/11 (20130101) C12N 2501/13 (20130101) C12N 2501/22 (20130101) C12N 2501/115 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) G01N 33/58 (20130101) G01N 33/6893 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156891 | Kaushal |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| INVENTOR(S) | Sunjay Kaushal (Chicago, Illinois) |
| ABSTRACT | Embodiments of the disclosure concern compositions and methods of use related to particular c-kit+ mesenchymal cells, including cardiac stem cells, obtained from a pediatric or neonatal individual. In specific embodiments, the cells, or conditioned medium or partial or total secretomes thereof, are provided in an effective amount to an individual in need thereof. |
| FILED | Friday, September 01, 2023 |
| APPL NO | 18/459685 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Original (OR) Class A61K 38/19 (20130101) A61K 38/195 (20130101) A61K 38/1833 (20130101) A61K 38/1866 (20130101) A61K 38/1891 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156899 | Chen |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Eye and Ear Infirmary (Boston, Massachusetts) |
| INVENTOR(S) | Zheng-Yi Chen (Somerville, Massachusetts) |
| ABSTRACT | Provided are methods and compositions for inducing cells of the inner ear (for example, cochlear and utricular hair cells) to reenter to cell cycle and to proliferate. More particularly, the invention relates to the use of agents that increase c-myc activity and/or Notch activity for inducing cell cycle reentry and proliferation of cochlear or utricular hair cells and/or cochlear or utricular supporting cells. The methods and compositions can be used to promote the proliferation of hair cells and/or supporting cells to treat a subject at risk of, or affected with, hearing loss or a subject at risk of, or affected with vestibular dysfunction. |
| FILED | Tuesday, April 07, 2020 |
| APPL NO | 16/842309 |
| ART UNIT | 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/65 (20130101) A61K 35/30 (20130101) A61K 38/16 (20130101) A61K 38/177 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/062 (20130101) C12N 2501/42 (20130101) C12N 2501/606 (20130101) C12N 2710/10341 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156908 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); New York Blood Center, Inc. (New York, New York) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota); New York Blood Center, Inc. (New York, New York) |
| INVENTOR(S) | Frank Jonathan Lee (Minneapolis, Minnesota); Qibin Geng (Minneapolis, Minnesota); Jian Shang (Minneapolis, Minnesota); Marc Jenkins (Minneapolis, Minnesota); Sung-Wook Hong (Minneapolis, Minnesota); Lanying Du (New York, New York); Wanbo Tai (New York, New York); Yushun Wan (Minneapolis, Minnesota) |
| ABSTRACT | The present disclosure provides virus like nanoparticles (VLPs), which are capable of displaying multiple copies of a SARS-CoV-2 antigen, for eliciting protective immunity against a SARS-CoV-2 infection, as well as polypeptides, compositions and methods thereof. |
| FILED | Tuesday, June 29, 2021 |
| APPL NO | 17/361486 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 39/215 (20130101) Peptides C07K 16/1002 (20230801) C07K 16/1003 (20230801) C07K 2317/52 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/20023 (20130101) C12N 2770/20034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156911 | Ogembo et al. |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Javier Gordon Ogembo (Duarte, California); Lorraine Zvichapera Mutsvunguma (Duarte, California); David H. Mulama (Duarte, California); Murali Muniraju (Duarte, California); Felix Wussow (Monrovia, California) |
| ABSTRACT | Vaccine compositions comprising a single KSHV-LP comprising two or more KSHV glycoproteins and/or one or more T cell antigens and methods of preventing or treating KSHV infections using the vaccine compositions. An expression system or a single expression vector for co-expressing two or more KSHV glycoproteins simultaneously to generate a vaccine comprising a single virus-like particle. The expression system may include a single plasmid inserted with two or more nucleic acid sequences that encode two or more KSHV glycoproteins linked by one or more linking sequences such that the KSHV glycoproteins are co-expressed simultaneously. |
| FILED | Friday, February 21, 2020 |
| APPL NO | 17/431856 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/17 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 2039/5258 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/22 (20180101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16423 (20130101) C12N 2710/16434 (20130101) C12N 2760/18134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156912 | Gendelman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| ASSIGNEE(S) | Board of Regents of the University of Nebraska (Lincoln, Nebraska) |
| INVENTOR(S) | Howard E. Gendelman (Omaha, Nebraska); R. Lee Mosley (Omaha, Nebraska) |
| ABSTRACT | Methods and compositions for treating central nervous system diseases and disorders are disclosed. In a particular embodiment, compositions comprising a nitrated alpha synuclein peptide are provided. The composition may further comprise an adjuvant that stimulates regulatory T cells and/or at least one pharmaceutically acceptable carrier. |
| FILED | Monday, May 20, 2013 |
| APPL NO | 14/401428 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/193 (20130101) A61K 38/193 (20130101) A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 38/2278 (20130101) A61K 38/2278 (20130101) A61K 39/0005 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/555 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156913 | Taylor et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTH CAROLINA CENTRAL UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | NORTH CAROLINA CENTRAL UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Darlene K. Taylor (Burlington, North Carolina); Melony A. Ochieng (Durham, North Carolina) |
| ABSTRACT | A delivery system using materials that form a liquogel or nanocarrier are described. The delivery system comprises hyperbranched polyglycerols (HPGs). The delivery system can include a drug or therapeutic agent and this system can be used to administer the drug or therapeutic agent locally. The delivery system provides for controlled release of the drug or therapeutic agent. |
| FILED | Friday, October 16, 2020 |
| APPL NO | 17/072804 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0024 (20130101) A61K 31/565 (20130101) A61K 31/4745 (20130101) A61K 47/34 (20130101) Original (OR) Class A61K 47/59 (20170801) A61K 47/551 (20170801) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/006 (20130101) Compositions of Macromolecular Compounds C08L 101/005 (20130101) C08L 101/005 (20130101) C08L 101/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156919 | Bloom et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida); Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana) |
| INVENTOR(S) | David C. Bloom (Gainesville, Florida); Alfred S. Lewin (Gainesville, Florida); Donna M. Neumann (Monona, Wisconsin); Zachary L. Watson (Gainesville, Florida); Sonal Sanjeev Tuli (Gainesville, Florida); Gregory Scott Schultz (Gainesville, Florida) |
| ABSTRACT | Aspects of the application relate to methods and compositions for delivering therapeutic nucleic acids to neural cells or tissue in a subject. Additional aspects of the application relate to therapeutic nucleic acids, for example therapeutic ribozymes, that are useful for inhibiting viral reactivation in a subject. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738987 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0091 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/22 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/062 (20130101) C12N 15/86 (20130101) C12N 15/861 (20130101) C12N 15/1133 (20130101) C12N 2310/20 (20170501) C12N 2310/121 (20130101) C12N 2320/32 (20130101) C12N 2510/00 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) C12N 2830/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156939 | Fahmy et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Tarek M. Fahmy (New Haven, Connecticut); Eric Stern (Jamaica Plain, Massachusetts); Richard A. Flavell (Guillford, Connecticut); Jason Park (New York, New York); Alyssa Siefert (Naugatuck, Connecticut); Stephen H. Wrzesinski (Slingerlands, New York) |
| ABSTRACT | A “nanolipogel” is a delivery vehicle including one or more lipid layer surrounding a hydrogel core, which may include an absorbent such as a cyclodextrin or ion-exchange resin. Nanolipogels can be constructed so as to incorporate a variety of different chemical entities that can subsequently be released in a controlled fashion. These different incorporated chemical entities can differ dramatically with respect to size and composition. Nanolipogels have been constructed to contain co-encapsulated proteins as well as small hydrophobic drugs within the interior of the lipid bilayer. Agents incorporated within nanolipogels can be released into the milieu in a controlled fashion, for example, nanolipogels provide a means of achieving simultaneous sustained release of agents that differ widely in chemical composition and molecular weight. Additionally, nanolipogels can favorably modulate biodistribution. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 17/399544 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/127 (20130101) Original (OR) Class A61K 9/1271 (20130101) A61K 9/1273 (20130101) A61K 9/1277 (20130101) A61K 9/5153 (20130101) A61K 31/343 (20130101) A61K 38/1841 (20130101) A61K 38/2013 (20130101) A61K 47/24 (20130101) A61K 47/40 (20130101) A61K 47/58 (20170801) A61K 47/6849 (20170801) A61K 47/6937 (20170801) A61K 47/6951 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/2812 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157018 | Khokhlova et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington); KONINKLIJKE PHILIPS N.V., A CORPORPORATION ORGANIZED AND EXISTING UNDER THE LAWS OF KINGDOM OF THE NETHERLANDS (Eindhoven, Netherlands) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); KONINKLIJKE PHILIPS N.V., A CORPORPORATION ORGANIZED AND EXISTING UNDER THE LAWS OF KINGDOM OF THE NETHERLANDS (Eindhoven, Netherlands) |
| INVENTOR(S) | Vera Khokhlova (Seattle, Washington); Michael R. Bailey (Seattle, Washington); Navid Farr (Seattle, Washington); Tatiana D. Khokhlova (Seattle, Washington); Wayne Kreider (Seattle, Washington); Adam D. Maxwell (Seattle, Washington); Ari Partanen (Andover, Massachusetts); Oleg A. Sapozhnikov (Seattle, Washington); George R. Schade (Seattle, Washington); Yak-Nam Wang (Seattle, Washington) |
| ABSTRACT | An example method includes generating an acoustic ultrasound wave that is focused at a focal point. The method further includes sequentially directing the focal point upon distinct portions of an object to form respective shock waves at the distinct portions of the object. The method further includes, via the respective shock waves, causing the distinct portions of the object to boil and form respective vapor cavities. The method further includes causing substantially uniform ablation of a region of the object that comprises the distinct portions. The substantially uniform ablation is caused via interaction of the respective shock waves with the respective vapor cavities. An example ablation system and an example non-transitory computer-readable medium, both related to the example method, are also disclosed. |
| FILED | Thursday, December 12, 2019 |
| APPL NO | 16/712680 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/22004 (20130101) A61B 2017/22007 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157759 | Varley et al. |
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| FUNDED BY |
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| APPLICANT(S) | HudsonAlpha Institute for Biotechnology (Huntsville, Alabama); The UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama); HudsonAlpha Institute for Biotechnology (Huntsville, Alabama) |
| INVENTOR(S) | Katherine E Varley (Salt Lake City, Utah); Richard M Myers (Huntsville, Alabama); Brian S Roberts (Huntsville, Alabama); Jason Gertz (Huntsville, Alabama); Donald J Buchsbaum (Birmingham, Alabama); Andres Forero-Torres (Birmingham, Alabama); Albert F LoBuglio (Birmingham, Alabama) |
| ABSTRACT | The present disclosure provides for and relates to novel fusion proteins and polypeptides expressed by breast cancer and other cancer cells, and to compositions, materials and methods for detecting, characterizing and treating said breast and other cancers. In one embodiment, the fusion polypeptides are read-through fusion transcripts. |
| FILED | Tuesday, August 27, 2019 |
| APPL NO | 16/552836 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/47 (20130101) Original (OR) Class C07K 14/4748 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157760 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Luke W. Koblan (Cambridge, Massachusetts); Christopher Gerard Wilson (Cambridge, Massachusetts); Jordan Leigh Doman (Cambridge, Massachusetts) |
| ABSTRACT | Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. The disclosure provides fusion proteins of nucleic acid programmable DNA binding proteins (napDNAbp), e.g., Cas9 or variants thereof, and nucleic acid editing proteins such as cytidine deaminase domains (e.g., novel cytidine deaminases generated by ancestral sequence reconstruction), and adenosine deaminases that deaminate adenine in DNA. Aspects of the disclosure relate to fusion proteins (e.g., base editors) that have improved expression and/or localize efficiently to the nucleus. In some embodiments, base editors are codon optimized for expression in mammalian cells. In some embodiments, base editors include multiple nuclear localization sequences (e.g., bipartite NLSs), e.g., at least two NLSs. In some embodiments, methods for targeted nucleic acid editing are provided. |
| FILED | Thursday, May 23, 2019 |
| APPL NO | 17/057398 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/4702 (20130101) Original (OR) Class C07K 2319/09 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/78 (20130101) Enzymes C12Y 305/04004 (20130101) C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157762 | Hinrichs et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Christian S. Hinrichs (Princeton, New Jersey); Benjamin Y. Jin (Bethesda, Maryland) |
| ABSTRACT | Disclosed are nucleic acids and polypeptides which provide the co-expression of interleukin (IL)-21 and IL-15 by a host cell, each interleukin being bound to the cell membrane by a cell membrane anchor moiety. Also disclosed are related recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, and methods of treating or preventing cancer. |
| FILED | Tuesday, May 02, 2023 |
| APPL NO | 18/310744 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4611 (20230501) A61K 39/4631 (20230501) A61K 39/4632 (20230501) A61K 39/46444 (20230501) A61K 39/464491 (20230501) A61K 39/464838 (20230501) A61K 2239/31 (20230501) A61K 2239/38 (20230501) A61K 2239/59 (20230501) Peptides C07K 14/5443 (20130101) C07K 14/7051 (20130101) Original (OR) Class C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) C12N 15/867 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157768 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | ICAHN SHOOL OF MEDICINE AT MOUNT SINAI (New York, New York); THE METHODIST HOSPITAL (Houston, Texas) |
| ASSIGNEE(S) | Icahn School of Medicine at Mount Sinai (New York, New York); The Methodist Hospital (Houston, Texas) |
| INVENTOR(S) | Shu-Hsia Chen (Houston, Texas); Ping-Ying Pan (Houston, Texas) |
| ABSTRACT | Antibodies and antibody fragments that specifically bind to LILRB2 are disclosed. Also provided herein are compositions comprising antibodies and antibody fragments that specifically bind to LILRB2 and methods of use thereof. Also provided are related chimeric antigen receptors (CARs) and cells comprising same (e.g., T cells, natural killer cells, or macrophages), and uses of the CARs and cells in targeting tumors and killing them, asthma treatment, or in targeting and removing infected cells (e.g., to treat infections or infectious diseases), or in suppressing immune system cells, as involved in autoimmune disease or transplant rejection. |
| FILED | Tuesday, September 17, 2019 |
| APPL NO | 17/276324 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2803 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157778 | Yao et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Wei Yao (El Dorado Hills, California); Ruiwu Liu (Sacramento, California); Kit S. Lam (Davis, California); Wenwu Xiao (Sacramento, California); Nancy Lane (Hillsborough, California) |
| ABSTRACT | The present invention provides compounds and pharmaceutical compositions of peptidomimetic ligands. The peptidomimetic ligands can be conjugated with phosphonate drugs. The compounds and pharmaceutical compositions of the present invention are useful in the treatment of osteoporosis and for the promotion of bone growth due to their specificity for the α4β1 integrin on mesenchymal stem cells and for the surface of bone. |
| FILED | Monday, January 11, 2021 |
| APPL NO | 17/146009 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/663 (20130101) A61K 47/64 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 19/10 (20180101) Peptides C07K 5/101 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157872 | Thon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Stellular Bio, Inc. (Watertown, Massachusetts) |
| ASSIGNEE(S) | Stellular Bio, Inc. (Watertown, Massachusetts) |
| INVENTOR(S) | Jonathan N. Thon (Watertown, Massachusetts); Jorge Valdez (Watertown, Massachusetts); Marcus Lehmann (Watertown, Massachusetts); Douglas G. Sabin (Woburn, Massachusetts); Shawn Murphy (Woburn, Massachusetts); Shweta V. Krishnan (Woburn, Massachusetts) |
| ABSTRACT | The instant disclosure provides a system comprising a plurality of stacked bioreactors, wherein the system is configured to provide a substantially equal flow rate of fluid and pressure drop through each of the plurality of bioreactors. In some embodiments, the flow of the fluid through each of the plurality of bioreactors is configured to generate physiological shear rates to induce a biological source material in the bioreactors to produce target biological products. |
| FILED | Friday, July 19, 2019 |
| APPL NO | 17/259829 |
| ART UNIT | 1799 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/10 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 25/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157884 | Bohm et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Alex A. Bohm (Newton, Massachusetts); Gretchen Meinke (Sharon, Massachusetts); Nahide Dalda (Dietenbach, Germany) |
| ABSTRACT | The present invention provides methods and kits for efficiently generating edited DNA, ranging from DNA molecules with simple point mutations to complex DNA libraries. The methods and kits use a single-stranded deoxyuridine (dU)-containing template to align a series of DNA oligomers that contain mutations relative to the template strand, giving rise to the sequence variation in the product. The methods and kits may be used to produce DNA libraries or to generate multiple, widely spaced mutations in a target sequence. |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 17/545612 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1252 (20130101) C12N 15/1031 (20130101) Original (OR) Class C12N 15/1093 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Enzymes C12Y 207/07007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157885 | Kaas et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Christian Schroeder Kaas (Boston, Massachusetts); Alejandro Chavez (New York, New York) |
| ABSTRACT | A method of screening is provided including providing a combination of a plurality of proliferating cell types wherein each proliferating cell type has a unique associated barcode within its genome that is different from other proliferating cell types of the plurality and wherein each proliferating cell type includes an exogenous gene that when expressed produces an associated phenotype to the proliferating cell type which alters proliferation of the cell type, introducing a perturbation to one or more of the plurality of proliferating cell types, inducing expression of one or more of the exogenous genes, determining the relative number of unique associated barcodes after a period of proliferation, and comparing the relative number of unique associated barcodes to a control relative number of unique associated barcodes to indicate the effect of the perturbation on the one or more of the plurality of proliferating cell types. |
| FILED | Thursday, July 06, 2017 |
| APPL NO | 16/315230 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 45/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/81 (20130101) C12N 15/905 (20130101) C12N 15/1075 (20130101) Original (OR) Class C12N 15/1075 (20130101) C12N 15/1079 (20130101) C12N 15/1082 (20130101) C12N 15/1082 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 2563/179 (20130101) C12Q 2563/179 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/06 (20130101) C40B 40/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157888 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Jeannie T. Lee (Boston, Massachusetts); Athanasios Zovoilis (Cambridge, Massachusetts) |
| ABSTRACT | Methods of using B2 or Alu nucleic acids, or antisense oligonucleotides that modulate the EZH2/B2 or EZH2/Alu interaction and have the capacity to alter cleavage of B2 and Alu RNA, for increasing or decreasing cell and organismal viability. |
| FILED | Wednesday, August 25, 2021 |
| APPL NO | 17/411313 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/113 (20130101) C12N 2310/314 (20130101) C12N 2310/321 (20130101) C12N 2310/341 (20130101) C12N 2310/3145 (20130101) C12N 2310/3231 (20130101) C12N 2310/3233 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157889 | Miller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Timothy M. Miller (St. Louis, Missouri); Mariah Lawler Hoye (St. Louis, Missouri); Ted Hyman (St. Louis, Missouri); Erica Koval (St. Louis, Missouri); Joseph Dougherty (St. Louis, Missouri) |
| ABSTRACT | The present invention relates to compositions and methods for detecting motor neuron-specific miRNAs in a population of cells or subject. More particularly, the invention relates to detecting motor neuron-specific miRNAs to detect and treat motor neuron diseases associated with dysregulation of motor neuron-specific miRNAs, such as Amyotrophic Lateral Sclerosis (ALS). |
| FILED | Thursday, January 13, 2022 |
| APPL NO | 17/575410 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2320/10 (20130101) C12N 2320/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157901 | Murthy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Shashi K. Murthy (Newton, Massachusetts); Bradley B. Collier (Jamaica Plain, Massachusetts) |
| ABSTRACT | Devices, systems, and methods can be used for the automated production of dendritic cells (DC) from dendritic cell progenitors, such as monocytes obtained from peripheral blood. The invention makes it possible to obtain sufficient quantities of a subject's own DC for use in preparing and characterizing vaccines, for activating and characterizing the activation state of the subject's immune response, and to aid in preventing and/or treating cancer or infectious disease. |
| FILED | Monday, December 05, 2022 |
| APPL NO | 18/061732 |
| ART UNIT | 1799 — Plants |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/00 (20130101) Peptides C07K 14/525 (20130101) C07K 14/535 (20130101) C07K 14/545 (20130101) C07K 14/5406 (20130101) C07K 14/5412 (20130101) Apparatus for Enzymology or Microbiology; C12M 1/22 (20130101) C12M 23/16 (20130101) C12M 23/42 (20130101) C12M 25/02 (20130101) C12M 29/10 (20130101) C12M 41/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) C12N 5/0639 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157903 | Braddock et al. |
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| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Demetrios Braddock (Guilford, Connecticut); Clemens Bergwitz (New Haven, Connecticut) |
| ABSTRACT | The present invention includes compositions and methods for treating and/or preventing renal and/or kidney stones in a human subject. In certain embodiments, the subject is administered certain ENPP1 polypeptides or ENPP3 polypeptides, mutants, or mutant fragments thereof. |
| FILED | Tuesday, May 07, 2019 |
| APPL NO | 17/052199 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) Peptides C07K 2319/02 (20130101) C07K 2319/30 (20130101) C07K 2319/31 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) Original (OR) Class Enzymes C12Y 306/01009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157918 | Wang |
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| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Wang-Xia Wang (Lexington, Kentucky) |
| ABSTRACT | A treatment method for cerebral vasospasm involves determining amounts of let-7b-5p, miR-9-3p, miR-142-3p, miR-15b-5p, miR-17-5p, miR-19b-3p, miR-20a-5p, miR-24-3p, miR-29a-3p, miR-125b-5p, and miR-142-3p in a biological sample obtained from a subject following aneurysmal subarachnoid hemorrhage (aSAH) to identify the subject as having an elevated risk of cerebral vasospasm, and administering a treatment to the subject when the elevated risk of cerebral vasospasm is identified. |
| FILED | Tuesday, September 07, 2021 |
| APPL NO | 17/468439 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4422 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158399 | Racioppi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Luigi Racioppi (Durham, North Carolina); Erik Nelson (Durham, North Carolina); Wei Huang (Durham, North Carolina); Nelson Chao (Durham, North Carolina); Donald McDonnell (Durham, North Carolina) |
| ABSTRACT | Provided herein are compositions including a CaMKK2 inhibitor and an anti-cancer therapeutic agent and methods of treating cancer in a subject by administering a therapeutically effective amount of the composition to a subject. The subject may be selected for treatment based on an immune cell measurement of a sample from the subject. Methods of treating cancer by administering a therapeutically effective amount of a CaMKK2 inhibitor, and administering a therapeutically effective amount of an anti-cancer therapeutic agent to the subject are also provided. Kits including combination of a CaMKK2 inhibitor and another anti-cancer therapeutic agent are also provided. |
| FILED | Monday, August 07, 2017 |
| APPL NO | 16/323482 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) A61K 39/001129 (20180801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) Original (OR) Class G01N 33/57415 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158458 | Du et al. |
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| FUNDED BY |
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| APPLICANT(S) | Florida Atlantic University Board of Trustees (Boca Raton, Florida) |
| ASSIGNEE(S) | Florida Atlantic University Board of Trustees (Boca Raton, Florida) |
| INVENTOR(S) | E Du (Boca Raton, Florida); Yuhao Qiang (Boca Raton, Florida); Darryl Dieujuste (North Miami, Florida); Jia Liu (Boca Raton, Florida) |
| ABSTRACT | An exemplary portable automated device is developed for in vitro testing of blood vascular occlusion as a result of sickle cell disease. The portable automated device may be controlled by a computer (e.g., smartphone) application. Calibration of the portable device may be performed using a component of known impedance value. With the developed portable automated device, analysis may be performed on sickle cell samples on a microfluidic platform that mimics the structure of human capillaries. Significant differences in cell impedance signals may be observed between sickle cells and normal cells, as well as between sickle cells under hypoxia and normoxia conditions. |
| FILED | Thursday, May 06, 2021 |
| APPL NO | 17/313235 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2300/0645 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 33/0022 (20130101) Original (OR) Class G01N 33/491 (20130101) G01N 33/6893 (20130101) G01N 33/48707 (20130101) G01N 33/48728 (20130101) G01N 2001/4088 (20130101) G01N 2800/224 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158475 | Czarnecki et al. |
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| FUNDED BY |
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| APPLICANT(S) | NanoCytomics, LLC (Evanston, Illinois); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | NanoCytomics, LLC (Evanston, Illinois); Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Jarema Czarnecki (Evanston, Illinois); Justin Derbas (Evanston, Illinois); Sergey Rozhok (Evanston, Illinois); Hariharan Subramanian (Mundelein, Illinois); Parvathi Viswanathan (Evanston, Illinois) |
| ABSTRACT | Systems and methods that enable automated spray deposition of biological specimens carried on microscope slides are described herein. Aspects of the technology are directed, for example, to automated specimen deposition systems and methods of generating high-quality, reproducible specimen-bearing microscope slides in automated processing systems. |
| FILED | Monday, February 06, 2023 |
| APPL NO | 18/164918 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/312 (20130101) G01N 1/2813 (20130101) G01N 35/00029 (20130101) Original (OR) Class G01N 35/00871 (20130101) G01N 35/1011 (20130101) G01N 35/1065 (20130101) G01N 2001/317 (20130101) G01N 2035/00138 (20130101) G01N 2035/00168 (20130101) G01N 2035/00881 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158512 | Sylvester et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Turing Medical Technologies, Inc (St. Louis, Missouri) |
| ASSIGNEE(S) | TURING MEDICAL TECHNOLOGIES INC. (St. Louis, Missouri) |
| INVENTOR(S) | Chad Sylvester (St. Louis, Missouri); Deanna Greene (St. Louis, Missouri); Scott Marek (St. Louis, Missouri); Scott Norris (St. Louis, Missouri); Jarod Roland (St. Louis, Missouri); Evan Gordon (St. Louis, Missouri); Timothy Laumann (St. Louis, Missouri); Damien Fair (St. Louis, Missouri); Kenneth Bruener (St. Louis, Missouri); Nico Dosenbach (St. Louis, Missouri) |
| ABSTRACT | A method of performing personalized neuromodulation on a subject is provided. The method includes acquiring functional magnetic resonance imaging (fMRI) data of a brain of the subject. The method also includes calculating functional connectivity of the brain between a voxel in a subcortical region of the brain and a voxel in a cortical region of the brain, based on the fMRI data. The method also includes identifying a target location in the brain to be targeted by neuromodulation based on the calculated functional connectivity. |
| FILED | Thursday, January 19, 2023 |
| APPL NO | 18/098886 |
| ART UNIT | 3798 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0036 (20180801) A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/4064 (20130101) A61B 5/7246 (20130101) A61B 2576/026 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3727 (20130101) A61N 1/36189 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) Original (OR) Class G01R 33/56366 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158571 | Fiolka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Reto P. Fiolka (Dallas, Texas); Tonmoy Chakraborty (Dallas, Texas); Bingying Chen (Dallas, Texas) |
| ABSTRACT | An imaging system configured to transform a lateral scan motion into axial refocusing, thus enabling aberration free remote focusing. In one embodiment, the imaging system provides aberration free remote focusing by causing a beam of light to be scanned over a stationary mirror having a variable height in the scan direction, thereby causing the beam of light to be defocused in an axial direction in the return direction (e.g., the direction of propagation for the reflected beam of light). By configuring the back-reflected light resulting from the lateral scan component as described herein, a pure axial scan motion may be obtained at the rate of the employed (lateral) scanning technology (e.g., a GSM). This capability allows the imaging system of the present inventive concept to leverage rapid lateral scan technologies to produce rapid axial displacement of the axial focus of the beam of light. |
| FILED | Thursday, February 25, 2021 |
| APPL NO | 17/185233 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/06 (20130101) Original (OR) Class G02B 21/361 (20130101) Pictorial Communication, e.g Television H04N 23/56 (20230101) H04N 23/74 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159403 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); University Hospitals Cleveland Medical Center (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Cristian Barrera (Shaker Heights, Ohio); Mohammadhadi Khorrami (Cleveland Heights, Ohio); Prantesh Jain (Cleveland, Ohio); Afshin Dowlati (Solon, Ohio) |
| ABSTRACT | The present disclosure relates to a non-transitory computer-readable medium storing computer-executable instructions that, when executed, cause a processor to perform operations, including generating an imaging data set having both scan data and digitized biopsy data from a patient with small cell lung cancer (SCLC). Scan derived features are extracted from the scan data and biopsy derived features are extracted from the digitized biopsy data. A radiomic-pathomic risk score (RPRS) is calculated from one or more of the scan derived features and one or more of the biopsy derived features. The RPRS is indicative of a prognosis of the patient. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/670817 |
| ART UNIT | 2635 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7264 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/40 (20130101) G06T 2207/10081 (20130101) G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159406 | Buckler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| INVENTOR(S) | Andrew J. Buckler (Boston, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A Moulton (Amesbury, Massachusetts); David S. Paik (Boston, Massachusetts) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Tuesday, December 19, 2023 |
| APPL NO | 18/545542 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/24 (20230101) G06F 18/211 (20230101) G06F 18/2148 (20230101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 3/00 (20130101) G06T 5/73 (20240101) G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10048 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10101 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/30096 (20130101) G06T 2207/30104 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/764 (20220101) G06V 20/69 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 12156725 | Loh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Kenneth Loh (San Diego, California); Yun-An Lin (San Diego, California) |
| ABSTRACT | Systems and methods relating to a smart elastic fabric tape are disclosed. For example, a method may include interrogating a sensing mesh using an electrical impedance tomography (EIT) device, wherein the sensing mesh is affixed onto skin nearby a musculoskeletal (MSK) region of interest, wherein the sensing mesh comprises a nanocomposite thin film disposed on elastic fabric tape, and wherein the sensing mesh forms a geometrical pattern on the skin; generating, in real-time, EIT conductivity maps from interrogating the sensing mesh; and generating, in real time, strain distribution and strain directionality data of the MSK region of interest based on the EIT conductivity maps. |
| FILED | Monday, July 19, 2021 |
| APPL NO | 17/379522 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0536 (20130101) Original (OR) Class A61B 5/6831 (20130101) A61B 2562/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157126 | Cooks et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Zhenwei Wei (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to systems and methods for synthesizing a reaction product and increasing yield of the same. In certain aspects, the invention provides a multi-mode reaction system in which in a first mode one or more valves of the system are configured to cause reagents to flow from one or more reagent reservoirs of the system through one or more components of the system to generate a reaction product; and in a second mode the one or more valves are configured to change flow within the system such that the one or more reagent reservoirs are isolated from a remainder of the system and the generated reaction product and any remaining reactants are recycled back through the multi-mode reaction system to increase a yield of the reaction product. |
| FILED | Wednesday, February 24, 2021 |
| APPL NO | 17/183691 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 7/02 (20130101) B01L 7/52 (20130101) Original (OR) Class B01L 2300/087 (20130101) B01L 2300/1894 (20130101) B01L 2400/0487 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157579 | Ulrich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | THE AEROSPACE CORPORATION (El Segundo, California) |
| INVENTOR(S) | Evan R. Ulrich (Hermosa Beach, California); Robert Edward Oberto (Manhattan Beach, California) |
| ABSTRACT | An aircraft for generating torque. The aircraft includes a motor coupling a lifting rotor and a torque rotor, and is configured to spin the lifting rotor in a first direction to generate lift and spin the torque rotor in a second direction to generate drag-torque. The torque rotor and the lifting rotor are coupled or decoupled from one another during flight or on ground. |
| FILED | Friday, November 13, 2020 |
| APPL NO | 17/097464 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/24 (20130101) B64D 35/06 (20130101) Original (OR) Class Unmanned aerial vehicles [UAV]; equipment therefor B64U 10/13 (20230101) B64U 30/291 (20230101) B64U 2101/30 (20230101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157759 | Varley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HudsonAlpha Institute for Biotechnology (Huntsville, Alabama); The UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama); HudsonAlpha Institute for Biotechnology (Huntsville, Alabama) |
| INVENTOR(S) | Katherine E Varley (Salt Lake City, Utah); Richard M Myers (Huntsville, Alabama); Brian S Roberts (Huntsville, Alabama); Jason Gertz (Huntsville, Alabama); Donald J Buchsbaum (Birmingham, Alabama); Andres Forero-Torres (Birmingham, Alabama); Albert F LoBuglio (Birmingham, Alabama) |
| ABSTRACT | The present disclosure provides for and relates to novel fusion proteins and polypeptides expressed by breast cancer and other cancer cells, and to compositions, materials and methods for detecting, characterizing and treating said breast and other cancers. In one embodiment, the fusion polypeptides are read-through fusion transcripts. |
| FILED | Tuesday, August 27, 2019 |
| APPL NO | 16/552836 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/47 (20130101) Original (OR) Class C07K 14/4748 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157760 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Luke W. Koblan (Cambridge, Massachusetts); Christopher Gerard Wilson (Cambridge, Massachusetts); Jordan Leigh Doman (Cambridge, Massachusetts) |
| ABSTRACT | Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. The disclosure provides fusion proteins of nucleic acid programmable DNA binding proteins (napDNAbp), e.g., Cas9 or variants thereof, and nucleic acid editing proteins such as cytidine deaminase domains (e.g., novel cytidine deaminases generated by ancestral sequence reconstruction), and adenosine deaminases that deaminate adenine in DNA. Aspects of the disclosure relate to fusion proteins (e.g., base editors) that have improved expression and/or localize efficiently to the nucleus. In some embodiments, base editors are codon optimized for expression in mammalian cells. In some embodiments, base editors include multiple nuclear localization sequences (e.g., bipartite NLSs), e.g., at least two NLSs. In some embodiments, methods for targeted nucleic acid editing are provided. |
| FILED | Thursday, May 23, 2019 |
| APPL NO | 17/057398 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/4702 (20130101) Original (OR) Class C07K 2319/09 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 9/78 (20130101) Enzymes C12Y 305/04004 (20130101) C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157762 | Hinrichs et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Christian S. Hinrichs (Princeton, New Jersey); Benjamin Y. Jin (Bethesda, Maryland) |
| ABSTRACT | Disclosed are nucleic acids and polypeptides which provide the co-expression of interleukin (IL)-21 and IL-15 by a host cell, each interleukin being bound to the cell membrane by a cell membrane anchor moiety. Also disclosed are related recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, and methods of treating or preventing cancer. |
| FILED | Tuesday, May 02, 2023 |
| APPL NO | 18/310744 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/4611 (20230501) A61K 39/4631 (20230501) A61K 39/4632 (20230501) A61K 39/46444 (20230501) A61K 39/464491 (20230501) A61K 39/464838 (20230501) A61K 2239/31 (20230501) A61K 2239/38 (20230501) A61K 2239/59 (20230501) Peptides C07K 14/5443 (20130101) C07K 14/7051 (20130101) Original (OR) Class C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) C12N 15/867 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157791 | Rush et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Anthony M. Rush (San Diego, California); Nathan Gianneschi (San Diego, California); Carrie James (San Diego, California) |
| ABSTRACT | Provided herein are compositions and methods of making high density nucleic acid polymers. |
| FILED | Wednesday, February 10, 2021 |
| APPL NO | 17/172793 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/00 (20130101) Peptides C07K 14/003 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/02 (20130101) Original (OR) Class C08G 2261/128 (20130101) C08G 2261/143 (20130101) C08G 2261/418 (20130101) C08G 2261/3324 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157872 | Thon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Stellular Bio, Inc. (Watertown, Massachusetts) |
| ASSIGNEE(S) | Stellular Bio, Inc. (Watertown, Massachusetts) |
| INVENTOR(S) | Jonathan N. Thon (Watertown, Massachusetts); Jorge Valdez (Watertown, Massachusetts); Marcus Lehmann (Watertown, Massachusetts); Douglas G. Sabin (Woburn, Massachusetts); Shawn Murphy (Woburn, Massachusetts); Shweta V. Krishnan (Woburn, Massachusetts) |
| ABSTRACT | The instant disclosure provides a system comprising a plurality of stacked bioreactors, wherein the system is configured to provide a substantially equal flow rate of fluid and pressure drop through each of the plurality of bioreactors. In some embodiments, the flow of the fluid through each of the plurality of bioreactors is configured to generate physiological shear rates to induce a biological source material in the bioreactors to produce target biological products. |
| FILED | Friday, July 19, 2019 |
| APPL NO | 17/259829 |
| ART UNIT | 1799 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/08 (20130101) C12M 23/10 (20130101) C12M 23/16 (20130101) Original (OR) Class C12M 25/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157956 | Tassev |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Vladimir Tassev (Beavercreek, Ohio) |
| ABSTRACT | A method of performing HVPE heteroepitaxy comprises exposing a substrate to a carrier gas, a first precursor gas, a Group II/III element, and ternary-forming gasses (V/VI group precursor), to form a heteroepitaxial growth of a binary, ternary, and/or quaternary compound on the substrate; wherein the carrier gas is H2, wherein the first precursor gas is HCl, the Group II/III element comprises at least one of Zn, Cd, Hg, Al, Ga, and In; and wherein the ternary-forming gasses comprise at least two or more of AsH3 (arsine), PH3 (phosphine), H2Se (hydrogen selenide), H2Te (hydrogen telluride), SbH3 (hydrogen antimonide, or antimony tri-hydride, or stibine), H2S (hydrogen sulfide), NH3 (ammonia), and HF (hydrogen fluoride); flowing the carrier gas over the Group II/III element; exposing the substrate to the ternary-forming gasses in a predetermined ratio of first ternary-forming gas to second ternary-forming gas (1tf:2tf ratio); and changing the 1tf:2tf ratio over time. |
| FILED | Monday, October 17, 2022 |
| APPL NO | 18/046950 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/02 (20130101) C30B 25/04 (20130101) Original (OR) Class C30B 25/18 (20130101) C30B 29/40 (20130101) C30B 29/42 (20130101) C30B 29/44 (20130101) C30B 29/48 (20130101) C30B 29/403 (20130101) C30B 29/406 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3556 (20130101) G02F 1/3558 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/024 (20130101) H01L 21/0254 (20130101) H01L 21/0262 (20130101) H01L 21/02293 (20130101) H01L 21/02387 (20130101) H01L 21/02389 (20130101) H01L 21/02392 (20130101) H01L 21/02395 (20130101) H01L 21/02398 (20130101) H01L 21/02458 (20130101) H01L 21/02461 (20130101) H01L 21/02463 (20130101) H01L 21/02466 (20130101) H01L 21/02505 (20130101) H01L 21/02538 (20130101) H01L 21/02543 (20130101) H01L 21/02546 (20130101) H01L 21/02549 (20130101) H01L 21/02551 (20130101) H01L 21/02568 (20130101) H01L 21/02658 (20130101) H01L 31/1828 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158327 | McNicholas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | William E. McNicholas (Ellettsville, Indiana); Joshua E. Gwaltney (Sandborn, Indiana); Eric Scheid (Bloomington, Indiana); Matt E. Cummings (Bedford, Indiana); Andrew Richard Davis (Mesa, Arizona) |
| ABSTRACT | Provided is a frangible munitions device optimized for a dome and cylinder that yields fragments having shapes corresponding to a predetermined embossment pattern upon explosive rupture. The embossment pattern includes a first set of inner regular hexagonal embossments formed into the dome and cylinder that are aligned with the axis of the cylinder, and a second set of outer pre-deformed hexagonal shapes that distort to produce regular hexagonal shapes after drawing into the cylinder wall. The second set of shapes are separated by sharp transition regions. The shapes are embossed in a repeated pattern around the hollow cylinder and the dome top. The dome yields a plurality of fragments having shapes corresponding to the first set of inner regular hexagonal embossments upon explosive rupture, while the cylinder yields a plurality of fragments having shapes corresponding to the second set of outer pre-deformed hexagonal embossments upon explosive rupture. |
| FILED | Friday, June 23, 2023 |
| APPL NO | 18/213476 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/22 (20130101) F42B 12/24 (20130101) Original (OR) Class F42B 27/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158399 | Racioppi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Luigi Racioppi (Durham, North Carolina); Erik Nelson (Durham, North Carolina); Wei Huang (Durham, North Carolina); Nelson Chao (Durham, North Carolina); Donald McDonnell (Durham, North Carolina) |
| ABSTRACT | Provided herein are compositions including a CaMKK2 inhibitor and an anti-cancer therapeutic agent and methods of treating cancer in a subject by administering a therapeutically effective amount of the composition to a subject. The subject may be selected for treatment based on an immune cell measurement of a sample from the subject. Methods of treating cancer by administering a therapeutically effective amount of a CaMKK2 inhibitor, and administering a therapeutically effective amount of an anti-cancer therapeutic agent to the subject are also provided. Kits including combination of a CaMKK2 inhibitor and another anti-cancer therapeutic agent are also provided. |
| FILED | Monday, August 07, 2017 |
| APPL NO | 16/323482 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) A61K 39/001129 (20180801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56972 (20130101) Original (OR) Class G01N 33/57415 (20130101) G01N 2800/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158421 | Diebold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Eric D. Diebold (Los Angeles, California); Bahram Jalali (Los Angeles, California); Brandon Buckley (Los Angeles, California) |
| ABSTRACT | Apparatus and methods for fluorescence imaging using radiofrequency multiplexed excitation. One apparatus splits an excitation laser beam into two arms of a Mach-Zehnder interferometer. The light in the first beam is frequency shifted by an acousto-optic deflector, which is driven by a phase-engineered radiofrequency comb designed to minimize peak-to-average power ratio. This RF comb generates multiple deflected optical beams possessing a range of output angles and frequency shifts. The second beam is shifted in frequency using an acousto-optic frequency shifter. After combining at a second beam splitter, the two beams are focused to a line on the sample using a conventional laser scanning microscope lens system. The acousto-optic deflectors frequency-encode the simultaneous excitation of an entire row of pixels, which enables detection and de-multiplexing of fluorescence images using a single photomultiplier tube and digital phase-coherent signal recovery techniques. |
| FILED | Monday, May 16, 2022 |
| APPL NO | 17/745206 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/05 (20130101) G01N 21/6408 (20130101) Original (OR) Class G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 2021/6415 (20130101) G01N 2021/6419 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/0076 (20130101) G02B 21/0084 (20130101) G02B 27/1006 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158422 | Diebold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Eric D. Diebold (Los Angeles, California); Bahram Jalali (Los Angeles, California); Brandon Buckley (Los Angeles, California) |
| ABSTRACT | Apparatus and methods for fluorescence imaging using radiofrequency multiplexed excitation. One apparatus splits an excitation laser beam into two arms of a Mach-Zehnder interferometer. The light in the first beam is frequency shifted by an acousto-optic deflector, which is driven by a phase-engineered radiofrequency comb designed to minimize peak-to-average power ratio. This RF comb generates multiple deflected optical beams possessing a range of output angles and frequency shifts. The second beam is shifted in frequency using an acousto-optic frequency shifter. After combining at a second beam splitter, the two beams are focused to a line on the sample using a conventional laser scanning microscope lens system. The acousto-optic deflectors frequency-encode the simultaneous excitation of an entire row of pixels, which enables detection and de-multiplexing of fluorescence images using a single photomultiplier tube and digital phase-coherent signal recovery techniques. |
| FILED | Monday, June 26, 2023 |
| APPL NO | 18/214292 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/05 (20130101) G01N 21/6408 (20130101) Original (OR) Class G01N 21/6458 (20130101) G01N 21/6486 (20130101) G01N 2021/6415 (20130101) G01N 2021/6419 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 21/16 (20130101) G02B 21/0076 (20130101) G02B 21/0084 (20130101) G02B 27/1006 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158431 | Dean et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| ASSIGNEE(S) | PRECISION COMBUSTION, Inc. (North Haven, Connecticut) |
| INVENTOR(S) | Robert W. Dean (Enfield, Connecticut); Codruta Maria Zoican-Loebick (North Haven, Connecticut) |
| ABSTRACT | A colorimetric method for detecting copper in a liquid hydrocarbon, preferably, a liquid hydrocarbon fuel, in particular an aviation fuel. A test kit for use in administering the test method is also described. |
| FILED | Thursday, June 16, 2022 |
| APPL NO | 17/841768 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/10 (20130101) C10L 2200/043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158511 | Nwokoye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Chidubem A. Nwokoye (Germantown, Maryland); JinHyeon Yoo (Germantown, Maryland); Nicholas J. Jones (Fairfax, Virginia) |
| ABSTRACT | Magnon excitation and detection systems, apparatus, and methods are provided. The systems and apparatus may include magnon exciters and magnon detectors. The systems and apparatus are used in accordance with methods for exciting and detecting magnons. |
| FILED | Tuesday, November 21, 2023 |
| APPL NO | 18/515485 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/323 (20130101) Original (OR) Class G01R 33/34053 (20130101) Transmission H04B 10/90 (20130101) H04B 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158625 | Hosseini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kaveh Hosseini (San Jose, California); Xiaoqian Li (Chandler, Arizona); Conor O'Keeffe (Cork, Iran); Jing Fang (Santa Clara, California); Kevin P. Ma (Beaverton, Oregon); Shamsul Abedin (Portland, Oregon) |
| ABSTRACT | Embodiments described herein may be related to apparatuses, processes, and techniques related to a bidirectional optical grating coupler that may be used for testing. A photonic apparatus includes a first layer with electro-optical circuitry that is optically coupled with a bidirectional optical grating coupler. A second layer is physically coupled with a first side of the first layer and includes a first light path to optically coupled with the bidirectional optical grating coupler. A third layer is physically coupled with a second side of the first layer opposite the first side of the first layer, and includes a second light path that optically couples with the bidirectional grating coupler. Operational testing of the electro-optical circuitry is based in part on light received or transmitted through the second light path. Other embodiments may be described and/or claimed. |
| FILED | Wednesday, December 23, 2020 |
| APPL NO | 17/132967 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4214 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 22/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158852 | Pawlowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Robert Pawlowski (Beaverton, Oregon); Bharadwaj Krishnamurthy (Hillsboro, Oregon); Shruti Sharma (Hillsboro, Oregon); Byoungchan Oh (Hillsboro, Oregon); Jing Fang (Santa Clara, California); Daniel Klowden (Portland, Oregon); Jason Howard (Portland, Oregon); Joshua Fryman (Corvallis, Oregon) |
| ABSTRACT | Systems, methods, and apparatuses for direct memory access instruction set architecture support for flexible dense compute using a reconfigurable spatial array are described. In one embodiment, a processor includes a first type of hardware processor core that includes a two-dimensional grid of compute circuits, a memory, and a direct memory access circuit coupled to the memory and the two-dimensional grid of compute circuits; and a second different type of hardware processor core that includes a decoder circuit to decode a single instruction into a decoded single instruction, the single instruction including a first field to identify a base address of two-dimensional data in the memory, a second field to identify a number of elements in each one-dimensional array of the two-dimensional data, a third field to identify a number of one-dimensional arrays of the two-dimensional data, a fourth field to identify an operation to be performed by the two-dimensional grid of compute circuits, and a fifth field to indicate the direct memory access circuit is to move the two-dimensional data indicated by the first field, the second field, and the third field into the two-dimensional grid of compute circuits and the two-dimensional grid of compute circuits is to perform the operation on the two-dimensional data according to the fourth field, and an execution circuit to execute the decoded single instruction according to the fields. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/358832 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 13/28 (20130101) Original (OR) Class G06F 2213/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158862 | Kaddoura |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Architecture Technology Corporation (Eden Prairie, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Maher N. Kaddoura (Maple Grove, Minnesota) |
| ABSTRACT | Software configured to receive a first record is provided. The first record includes first record data, a first identification code in an identification code field, a first hash in a record hash field, and a second hash in a previous record pointer field. The first hash is calculated based on the first record data, the first identification code, and the second hash. The second hash is included in a record hash field of a second record. The second record includes the first identification code in its identification code field. A first block is generated having the first record in a first record field, a third hash in a block hash field, and a fourth hash in a previous block pointer field. The third hash is calculated based on the first record and the fourth hash. The fourth hash is included in a block hash field of a second block. The second block is part of a main ledger that includes a third block having the second record in its record field. The third block is positioned prior to the second block in the main ledger. |
| FILED | Monday, October 03, 2022 |
| APPL NO | 17/937769 |
| ART UNIT | 2451 — Computer Networks |
| CURRENT CPC | Electric Digital Data Processing G06F 16/1834 (20190101) Original (OR) Class G06F 16/2379 (20190101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/50 (20220501) H04L 9/0643 (20130101) H04L 9/3239 (20130101) H04L 9/3247 (20130101) H04L 45/64 (20130101) H04L 67/104 (20130101) H04L 67/1097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159195 | Akhalwaya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Ismail Yunus Akhalwaya (Emmarentia, South Africa); Kenneth Clarkson (Madison, New Jersey); Lior Horesh (North Salem, New York); Mark Squillante (Greenwich, Connecticut); Shashanka Ubaru (Ossining, New York); Vasileios Kalantzis (White Plains, New York) |
| ABSTRACT | Techniques and a system to facilitate estimation of a quantum phase, and more specifically, to facilitate estimation of an expectation value of a quantum state, by utilizing a hybrid of quantum and classical methods are provided. In one example, a system is provided. The system can comprise a memory that stores computer executable components and a processor that executes the computer executable components stored in the memory. The computer executable components can include an encoding component and a learning component. The encoding component can encode an expectation value associated with a quantum state. The learning component can utilize stochastic inference to determine the expectation value based on an uncollapsed eigenvalue pair. |
| FILED | Thursday, March 30, 2023 |
| APPL NO | 18/193082 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Electric Digital Data Processing G06F 17/11 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159226 | Hopkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Jonathan Hopkins (Los Angeles, California); Ali Hatamizadeh (Los Angeles, California); Yuanping Song (Los Angeles, California) |
| ABSTRACT | A boundary learning optimization tool for training neural networks with accurate models of parameterized flexure using a minimal number of numerically generated performance solutions generated from different design instantiations of those topologies. Performance boundaries are output by the neural network in optimization steps, with geometric parameters varied from smallest allowable feature sizes to largest geometrically compatible feature sizes for given constituent materials. The plotted performance boundaries define the design spaces of flexure systems toward allowing designers to visually identify which geometric versions of their synthesized topologies best achieve desired combinations of performance capabilities. |
| FILED | Thursday, December 31, 2020 |
| APPL NO | 17/139800 |
| ART UNIT | 2175 — Graphical User Interface and Document Processing |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159403 | Madabhushi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); University Hospitals Cleveland Medical Center (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Cristian Barrera (Shaker Heights, Ohio); Mohammadhadi Khorrami (Cleveland Heights, Ohio); Prantesh Jain (Cleveland, Ohio); Afshin Dowlati (Solon, Ohio) |
| ABSTRACT | The present disclosure relates to a non-transitory computer-readable medium storing computer-executable instructions that, when executed, cause a processor to perform operations, including generating an imaging data set having both scan data and digitized biopsy data from a patient with small cell lung cancer (SCLC). Scan derived features are extracted from the scan data and biopsy derived features are extracted from the digitized biopsy data. A radiomic-pathomic risk score (RPRS) is calculated from one or more of the scan derived features and one or more of the biopsy derived features. The RPRS is indicative of a prognosis of the patient. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/670817 |
| ART UNIT | 2635 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7264 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/40 (20130101) G06T 2207/10081 (20130101) G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159467 | Rasheed et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Novateur Research Solutions (Ashburn, Virginia); Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Novateur Reserch Solutions (Ashburn, Virginia); Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Zeeshan Rasheed (Ashburn, Virginia); Khurram Hassan-Shafique (Ashburn, Virginia); Maoxu Li (Ashburn, Virginia); Nicholas Raphael Gans (Plano, Texas); Cody Lee Lundberg (Burleson, Texas); Michael Edward Araujo (Euless, Texas) |
| ABSTRACT | A system for measuring surface deflection of a road includes a first stereo line-scan camera pair on a sensor rig and for capturing a first set of 3D images of a road surface; a second stereo line-scan camera pair on the sensor rig and for capturing a second set of 3D images of the road surface; at least one digital electro-optical (EO) camera rigidly attached to the sensor rig; an inertial measurement unit (IMU) detecting inertial forces acting upon the sensor rig; and a processor compensating for acceleration and vibration effects upon the sensor rig; and calculating the surface deflection of the road based on the first and second sets of 3D images. The processor utilizes imagery from the EO camera and inertial measurements from the IMU to produce 2D mosaics and 3D reconstructions of the road surface from the first and second sets of 3D images. |
| FILED | Wednesday, July 10, 2024 |
| APPL NO | 18/768725 |
| ART UNIT | 2484 — Recording and Compression |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 17/00 (20130101) Image or Video Recognition or Understanding G06V 20/588 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159929 | Keller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Stacia Keller (Santa Barbara, California); Umesh K. Mishra (Montecito, California) |
| ABSTRACT | An electronic device including a substrate a group III-V layer on or above the substrate, wherein the III-V layer has an in-plane lattice constant that is greater than that of gallium nitride or wherein the III-V layer is at least partially relaxed; and an active region including a coherently strained group III-V channel layer on or above the III-V layer; wherein electron mobility in the channel layer is increased by the strain. Structures with an in-plane lattice constant that is smaller than that of gallium nitride are used for increasing the hole mobility by strain. |
| FILED | Monday, December 07, 2020 |
| APPL NO | 17/114307 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/151 (20130101) H01L 29/205 (20130101) H01L 29/1029 (20130101) H01L 29/2003 (20130101) H01L 29/7781 (20130101) Original (OR) Class H01L 29/66462 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159980 | Hammond et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christopher J. Hammond (Bloomington, Indiana); Alexander M. Potter (Bloomington, Indiana) |
| ABSTRACT | Provided is a battery grid pellet adhesion/cohesion strength tester that can accurately determine the push-out strength of a battery grid pellet by measuring the binding of the active material to the battery grid during the pasting and curing process. A programmable test stand and force gage are used with a selectable active material punching tool fixture and a set of selectable set of grid location pins. Active material from a lead-acid battery is forced out of the battery grid at a programmed feed rate with the force gage reporting precise force measurements for each battery grid pellets adhesion/cohesion strength. The inventive device can be utilized as a quality control measure following the battery pasting and curing process, which will ensure that consistent and uniform adhesion/cohesion has occurred during battery manufacture, thereby avoiding battery premature performance failure. |
| FILED | Wednesday, May 18, 2022 |
| APPL NO | 17/747267 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 19/04 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/4285 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12160049 | Dawson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David Carlos Dawson (Lemon Grove, California) |
| ABSTRACT | A method for hybrid RF beamforming comprising: providing an antenna structure which comprises: a driven element, parasitic elements configured to couple/decouple a linearly polarized radiation pattern and arranged around the driven elements, a feed system comprising four ports that are 90 degrees out of phase with each other and are connected to the driven element, RF switches electrically connected to the parasitic elements and the four ports, and a controller operatively connected to the RF switches; selectively attenuating an output of each of the four ports with the controller according to a stored configuration, which is stored in a memory, by changing the four ports' respective phase or attenuation; and selectively changing a loading of each parasitic element by activating each parasitic element's corresponding RF switch with the controller according to the stored configuration so as to produce a desired null/beamforming of a main RF beam. |
| FILED | Wednesday, March 02, 2022 |
| APPL NO | 17/685031 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/24 (20130101) H01Q 3/26 (20130101) H01Q 3/36 (20130101) H01Q 3/2611 (20130101) Original (OR) Class H01Q 19/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12160508 | Gabrys et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Naval Information Warfare Center Pacific (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ryan Gabrys (San Diego, California); Luis M. Martinez (San Diego, California); Sunny James Fugate (San Diego, California); Mike Tall (San Diego, California) |
| ABSTRACT | A system and related methods that generate encryption keys using two inputs. The first input is random data measured or supplied at the time the encryption keys are created. The second input is predetermined data held by the server and device. Given knowledge of the predetermined data and the random data, the UxS will be able to regenerate its previous encryption keys and also to re-establish communication by the server and device. |
| FILED | Wednesday, May 11, 2022 |
| APPL NO | 17/742283 |
| ART UNIT | 2492 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0822 (20130101) H04L 9/0825 (20130101) H04L 9/0869 (20130101) Original (OR) Class H04L 9/0894 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12161052 | Yan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York); The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York); Govmt. of U.S. Navy (Washington, District of Columbia) |
| INVENTOR(S) | Rusen Yan (Ithaca, New York); Guru Bahadur Singh Khalsa (Ithaca, New York); John Wright (Ithaca, New York); H. Grace Xing (Ithaca, New York); Debdeep Jena (Ithaca, New York); D. Scott Katzer (Washington, District of Columbia); Neeraj Nepal (Washington, District of Columbia); Brian P. Downey (Washington, District of Columbia); David J. Meyer (Washington, District of Columbia) |
| ABSTRACT | Solid-state devices including a layer of a superconductor material epitaxially grown on a crystalline high thermal conductivity substrate, the superconductor material being one of TiNx, ZrNx, HfNx, VNx, NbNx, TaNx, MoNx, WNx, or alloys thereof, and one or more layers of a semiconducting or insulating or metallic material epitaxially grown on the layer of superconductor material, the semiconducting or insulating material being one of a Group III N material or alloys thereof or a Group 4b N material or SiC or ScN or alloys thereof. |
| FILED | Wednesday, March 06, 2019 |
| APPL NO | 16/978415 |
| ART UNIT | 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Electric solid-state devices not otherwise provided for H10N 60/12 (20230201) Original (OR) Class H10N 60/203 (20230201) H10N 60/0941 (20230201) H10N 69/00 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 12157098 | Kessler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas, Missouri) |
| INVENTOR(S) | Daniel S. Kessler (Stilwell, Kansas); Troy W. Leonard (Lee's Summit, Missouri) |
| ABSTRACT | A method for mixing, milling, and coating a plurality of constituents comprises placing the constituents in a container that includes a cylindrical inner surface; applying a first vibration to the container such that a motion of the vibration is parallel to a longitudinal axis of the container; and applying a second vibration to the container such that the motion of the vibration is not parallel to the longitudinal axis of the container. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/549972 |
| ART UNIT | 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 31/50 (20220101) Original (OR) Class B01F 35/422 (20220101) Apparatus for Applying Fluent Materials to Surfaces, in General B05C 3/05 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157275 | Moran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); 3D SYSTEMS, INC. (Houston, Texas) |
| ASSIGNEE(S) | Lawrence Livermore National Laboratory and 3D Systems, Inc. (, None) |
| INVENTOR(S) | Bryan D. Moran (Livermore, California); Brian J. Bauman (Livermore, California); Matthew Kenneth Gelber (Houston, Texas); Jordan Miller (Houston, Texas) |
| ABSTRACT | Provided herein is a system for producing a product. The system generally comprises a large-area micro-stereolithography system, an optical imaging system, and a controller in communication with the large-area micro-stereolithography system and the optical imaging system. The large-area micro-stereolithography system is capable of generating the product by optically polymerizing successive layers of a curable resin at a build plane. The controller is capable of analyzing a focus level of the reference target based on the captured image; and based on the analyzing, adjusting a focus property of the projected image beam of the stereolithography system. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 17/729077 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) B29C 64/393 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157369 | Correa |
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| FUNDED BY |
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| APPLICANT(S) | CUMMINS INC. (Columbus, Indiana) |
| ASSIGNEE(S) | Cummins Inc. (Columbus, Indiana) |
| INVENTOR(S) | Dixon Malcolm Correa (Columbus, Indiana) |
| ABSTRACT | An energy recovery drive system includes a motor-generator that is structured to selectively operate in a motor mode and a generator mode. A first shaft is operatively coupled to a transmission power take-off shaft. A second shaft is operatively coupled to the motor-generator and to an alternative power source. The energy recovery drive system is controllably operated in a plurality of operating modes. In a first operating mode, the motor-generator is in torque providing engagement with each of the first and second shafts. In a second operating mode, the motor-generator is in torque communicating engagement with each of the first and second shafts. In a third operating mode, which the motor-generator is in torque communicating engagement with the second shaft and is disengaged from transferring torque to the first shaft and from receiving torque from the first shaft. |
| FILED | Friday, February 12, 2021 |
| APPL NO | 17/175104 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 6/48 (20130101) B60K 6/387 (20130101) Original (OR) Class B60K 6/547 (20130101) B60K 25/06 (20130101) B60K 2006/4808 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 7/10 (20130101) B60L 50/15 (20190201) B60L 2260/24 (20130101) Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 20/11 (20160101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157845 | Hun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Diana Hun (Lenoir City, Tennessee); Pengfei Cao (Knoxville, Tennessee); Tomonori Saito (Knoxville, Tennessee); Zhen Zhang (Knoxville, Tennessee); Bingrui Li (Knoxville, Tennessee); Natasha Ghezawi (Rock Top, Tennessee) |
| ABSTRACT | A self-healing adhesive composition comprising a homogeneous mixture of: (i) a self-healing polymer containing hydrogen bonding groups or long-chain alkyl groups, wherein said hydrogen bonding groups comprise hydrogen bond donating groups and hydrogen bond accepting groups, and wherein said long-chain alkyl groups contain at least four carbon atoms; and (ii) an extrudable adhesive polymer base having a curable property and no self-healable property; wherein component (i) is present in the self-healing adhesive composition in an amount of at least 10 wt % and up to 70 wt % of the total of components (i) and (ii). Also described herein is a method of sealing a space (e.g., crack, gap, or pores) in a substrate material by at least partially filling the space with the self-healing adhesive composition described above and permitting the self-healing adhesive composition to harden over time without applying an external stimulus to induce hardening. |
| FILED | Thursday, December 10, 2020 |
| APPL NO | 17/117827 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 20/36 (20130101) C08F 120/36 (20130101) C08F 220/36 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/30 (20180101) Original (OR) Class C09J 133/14 (20130101) C09J 2433/00 (20130101) C09J 2475/00 (20130101) C09J 2483/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157908 | Jewett et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois); LanzaTech, Inc. (Skokie, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); LanzaTech, Inc. (Skokie, Illinois) |
| INVENTOR(S) | Michael Christopher Jewett (Evanston, Illinois); Antje Kruger-Gericke (Evanston, Illinois); Alexander Paul Mueller (Skokie, Illinois); Michael Koepke (Chicago, Illinois) |
| ABSTRACT | Disclosed are compositions, methods, and kits for performing cell-free RNA transcription and/or cell-free protein synthesis (CFPS). The disclosed compositions, methods, and kits include or utilize components prepared from a species of Clostridia such as cellular extracts from Clostridium autoethanogenum. |
| FILED | Tuesday, February 25, 2020 |
| APPL NO | 16/800844 |
| ART UNIT | 1675 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) C12N 9/1247 (20130101) C12N 15/1072 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) Original (OR) Class Enzymes C12Y 207/07006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158291 | Slaughter-Zrostlik et al. |
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| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Julie Slaughter-Zrostlik (Ames, Iowa); Vitalij K. Pecharsky (Ames, Iowa); Lucas Griffith (Ames, Iowa); Agata Czernuszewicz (Ames, Iowa) |
| ABSTRACT | The elastocaloric effect underpins a promising solid-state heat pumping technology that, when adopted for commercial and residential applications, can revolutionize the cooling and heating industry due to low environmental impact and substantial energy savings. Known operational demonstration devices based on the elastocaloric effect suffer from low endurance of materials and, in most experimental systems, from large footprints due to bulky actuators required to provide sufficient forces and displacements. We demonstrate a new approach which has the potential to enable a more effective exploitation of the elastocaloric effect by reducing the forces required for actuation. Thin strips of NiTi were incorporated into composite structures with base polymer, such that bending the structures results in either exclusively compression or exclusively tension applied to the elastocaloric strips. The structures allow compression of thin elastocaloric strips without buckling, realize more than 50% reduction in required forces for a given strain compared with axial loading, and open up a wide range of possibilities for compact, efficient elastocaloric devices. |
| FILED | Thursday, November 12, 2020 |
| APPL NO | 16/949744 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158449 | Findikoglu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Chevron U.S.A. Inc. (San Ramon, California); Triad National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Chevron U.S.A. Inc. (San Ramon, California) |
| INVENTOR(S) | Alp Tugrul Findikoglu (Los Alamos, New Mexico); Daniel Robert Chapman (San Ramon, California) |
| ABSTRACT | Combinations of multiple analytic techniques may be used to identify changes to a structure based on changes in characteristics of acoustic signals traveling along the structure. Acoustic signals traveling along the structure may be monitored to detect changes in characteristics of the acoustic signal from baseline signal characteristics. The changes in characteristics of the acoustic signals may be processed using multiple analytic techniques to provide analyses of the change in time-domain, in frequency-domain, and in mixed time-frequency-domain. The change to the structure may be identified based on a combination of the results of the analysis in time-domain, in frequency-domain, and in mixed time-frequency-domain. |
| FILED | Tuesday, June 18, 2019 |
| APPL NO | 17/620322 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/07 (20130101) G01N 29/12 (20130101) G01N 29/46 (20130101) G01N 29/50 (20130101) G01N 29/4427 (20130101) Original (OR) Class G01N 33/20 (20130101) G01N 2291/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158840 | Roberts |
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| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | David A. Roberts (Wellesley, Massachusetts) |
| ABSTRACT | Systems, apparatuses, and methods related to memory access statistics monitoring are described. A host is configured to map pages of memory for applications to a number of memory devices coupled thereto. A first memory device comprises a monitoring component configured to monitor access statistics of pages of memory mapped to the first memory device. A second memory device does not include a monitoring component capable of monitoring access statistics of pages of memory mapped thereto. The host is configured to map a portion of pages of memory for an application to the first memory device in order to obtain access statistics corresponding to the portion of pages of memory upon execution of the application despite there being space available on the second memory device and adjust mappings of the pages of memory for the application based on the obtained access statistics corresponding to the portion of pages. |
| FILED | Friday, November 17, 2023 |
| APPL NO | 18/512850 |
| ART UNIT | 2135 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0238 (20130101) Original (OR) Class G06F 12/0292 (20130101) G06F 12/0882 (20130101) G06F 13/1621 (20130101) G06F 13/1689 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158950 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jina Lee (Mountain View, California); Christopher B. Harrison (Livermore, California); Michael Bierma (Dublin, California); Kina Kincher-Winoto (Livermore, California); David Kavaler (Dublin, California) |
| ABSTRACT | Described herein are technologies related to generation of a summary of a function in binary code for review by an analyst. A first sequence to sequence model is configured to receive binary code (or a derivative thereof) and translate the binary code to an intermediate representation of the binary code, wherein the intermediate representation approximates source code for the binary code. A second sequence to sequence model is configured to receive the intermediate representation of the binary code and translate the intermediate representation to a human-readable summary of the binary code. |
| FILED | Thursday, January 21, 2021 |
| APPL NO | 17/154358 |
| ART UNIT | 2439 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/552 (20130101) G06F 21/554 (20130101) Original (OR) Class G06F 21/564 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159369 | Kudyshev et al. |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Zhaxylyk A. Kudyshev (West Lafayette, Indiana); Demid Sychev (West lafayette, Indiana); Zachariah Olson Martin (West Lafayette, Indiana); Simeon I. Bogdanov (West Lafayette, Indiana); Xiaohui Xu (West Lafayette, Indiana); Alexander Kildishev (West Lafayette, Indiana); Alexandra Boltasseva (West Lafayette, Indiana); Vladimir Shalaev (West Lafayette, Indiana) |
| ABSTRACT | A method of providing super-resolved images of a photon emitting particle is disclosed, which includes providing a machine-learning (ML) platform, wherein the ML platform is configured to receive pixel-based sparse autocorrelation data and generate a predicted super-resolved image of a photon emitting particle, receiving photons from the photon emitting particle by two or more photon detectors, each generating an electrical pulse associated with receiving an incident photon thereon, generating sparse autocorrelation data from the two or more photon detectors for each pixel within an image area, and inputting the pixel-based sparse autocorrelation data to the ML platform, thereby generating a predicted super-resolved image of the imaging area, wherein the resolution of the super-resolved image is improved by √n as compared to a classical optical microscope limited by Abbe diffraction limit. |
| FILED | Wednesday, July 06, 2022 |
| APPL NO | 17/858722 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/0072 (20130101) Image Data Processing or Generation, in General G06T 3/4046 (20130101) G06T 3/4053 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159686 | Sheridan |
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| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Patrick Michael Sheridan (Boulder, Colorado) |
| ABSTRACT | Disclosed in some examples are methods, systems, memory devices, and machine-readable mediums which store a single compressed value per line with a marker value in a front of the compressed version of the memory line. In some examples, the only value stored in the memory line is the value normally stored therein. This removes the complexity of the prediction tables and the inclusion of invalid values as well as preventing the penalty when those prediction tables are wrong. Furthermore, by inclusion of the marker in the beginning of the memory line, the system can quickly determine the compression status of the memory line without having to read the entire line. That is, it can quickly stop reading the rest of the memory line once the compressed data is read out which saves the memory device from having to read the entire line. |
| FILED | Thursday, July 14, 2022 |
| APPL NO | 17/865102 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 7/109 (20130101) G11C 7/1069 (20130101) G11C 7/1096 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159943 | Zhao et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yuji Zhao (Chandler, Arizona); Chen Yang (Tempe, Arizona); Houqiang Fu (Tempe, Arizona); Xuanqi Huang (Tempe, Arizona); Kai Fu (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Yuji Zhao (Chandler, Arizona); Chen Yang (Tempe, Arizona); Houqiang Fu (Tempe, Arizona); Xuanqi Huang (Tempe, Arizona); Kai Fu (Tempe, Arizona) |
| ABSTRACT | Fabricating a vertical-channel junction field-effect transistor includes forming an unintentionally doped GaN layer on a bulk GaN layer by metalorganic chemical vapor deposition, forming a Cr/SiO2 hard mask on the unintentionally doped GaN layer, patterning a fin by electron beam lithography, defining the Cr and SiO2 hard masks by reactive ion etching, improving a regrowth surface with inductively coupled plasma etching, removing hard mask residuals, regrowing a p-GaN layer, selectively etching the p-GaN layer, forming gate electrodes by electron beam evaporation, and forming source and drain electrodes by electron beam evaporation. The resulting vertical-channel junction field-effect transistor includes a doped GaN layer, an unintentionally doped GaN layer on the doped GaN layer, and a p-GaN regrowth layer on the unintentionally doped GaN layer. Portions of the p-GaN regrowth layer are separated by a vertical channel of the unintentionally doped GaN layer. |
| FILED | Friday, November 04, 2022 |
| APPL NO | 17/981178 |
| ART UNIT | 2813 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/3065 (20130101) H01L 21/3081 (20130101) H01L 29/1058 (20130101) H01L 29/2003 (20130101) H01L 29/8083 (20130101) Original (OR) Class H01L 29/66446 (20130101) H01L 29/66909 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12160005 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Da Deng (Troy, Michigan); Minjun Bae (Detroit, Michigan) |
| ABSTRACT | A device may include a metallic substrate and a plurality of nanorod arrays arranged on the substrate. The nanorod arrays may be made of porous metallic nanostructures and may appear black in color. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/396031 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/70 (20130101) H01M 4/628 (20130101) Original (OR) Class H01M 4/661 (20130101) H01M 4/667 (20130101) H01M 10/052 (20130101) H01M 2004/021 (20130101) H01M 2004/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12160096 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Fei Lu (Wynnewood, Pennsylvania); Hua Zhang (Philadelphia, Pennsylvania); Reza Kheirollahi (Philadelphia, Pennsylvania); Yao Wang (Philadelphia, Pennsylvania); Shuyan Zhao (Philadelphia, Pennsylvania) |
| ABSTRACT | With the fasting growth of renewable energy resources and DC supplied loads, DC electrical systems have been increasingly received attentions all over the world. DC breaker systems play a key role in protection systems for disconnecting sources and loads, and they are also used mainly for removing faulted sections from the system accurately and reliably. Solid state DC breakers benefit from fast response time and compactness features; however, due to the lack of zero current realization and high-power losses, the reliability and efficiency of these devices is low. The system proposes a solid-state DC breaker for medium voltage DC (MVDC) systems. The presented structure have two main parts: 1) a main conduction branch including stacked MV Silicon-Carbide (SiC) devices to improve the efficiency and provide a fast response time, 2) a breaker branch including a wireless capacitive coupling to avoid metal-to-metal contact and increase the overall reliability, and also a modular current pulse power supply to realize zero-current switching. |
| FILED | Tuesday, April 13, 2021 |
| APPL NO | 17/996088 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 9/54 (20130101) Emergency Protective Circuit Arrangements H02H 3/087 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12161002 | Zheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Xiaopeng Zheng (Lakewood, Colorado); Joseph Matthew Luther (Boulder, Colorado) |
| ABSTRACT | The present disclosure relates to a device that includes a perovskite layer; and a first layer that includes a molecule having a structure according to formula (I) Wherein the perovskite layer and the first layer are in physical contact, n is between 1 and 10, inclusively, R1 includes at least one of hydrogen, a first alkyl group, a first alkoxy group, and/or a first halogen, R2 includes at least one of hydrogen, a second alkyl group, a second alkoxy group, and/or a second halogen, R1 is bonded to aromatic ring (A) at carbon atom (1), carbon atom (2), carbon atom (3), or carbon atom (4), R2 is bonded to aromatic ring (B) at carbon atom (5), carbon atom (6), carbon atom (7), or carbon atom (8), and R1 and R2 are the same or different. |
| FILED | Friday, April 21, 2023 |
| APPL NO | 18/304701 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Organic electric solid-state devices H10K 30/40 (20230201) Original (OR) Class H10K 30/80 (20230201) H10K 85/211 (20230201) H10K 2102/101 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 12156913 | Taylor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTH CAROLINA CENTRAL UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | NORTH CAROLINA CENTRAL UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Darlene K. Taylor (Burlington, North Carolina); Melony A. Ochieng (Durham, North Carolina) |
| ABSTRACT | A delivery system using materials that form a liquogel or nanocarrier are described. The delivery system comprises hyperbranched polyglycerols (HPGs). The delivery system can include a drug or therapeutic agent and this system can be used to administer the drug or therapeutic agent locally. The delivery system provides for controlled release of the drug or therapeutic agent. |
| FILED | Friday, October 16, 2020 |
| APPL NO | 17/072804 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0024 (20130101) A61K 31/565 (20130101) A61K 31/4745 (20130101) A61K 47/34 (20130101) Original (OR) Class A61K 47/59 (20170801) A61K 47/551 (20170801) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 83/006 (20130101) Compositions of Macromolecular Compounds C08L 101/005 (20130101) C08L 101/005 (20130101) C08L 101/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156939 | Fahmy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Tarek M. Fahmy (New Haven, Connecticut); Eric Stern (Jamaica Plain, Massachusetts); Richard A. Flavell (Guillford, Connecticut); Jason Park (New York, New York); Alyssa Siefert (Naugatuck, Connecticut); Stephen H. Wrzesinski (Slingerlands, New York) |
| ABSTRACT | A “nanolipogel” is a delivery vehicle including one or more lipid layer surrounding a hydrogel core, which may include an absorbent such as a cyclodextrin or ion-exchange resin. Nanolipogels can be constructed so as to incorporate a variety of different chemical entities that can subsequently be released in a controlled fashion. These different incorporated chemical entities can differ dramatically with respect to size and composition. Nanolipogels have been constructed to contain co-encapsulated proteins as well as small hydrophobic drugs within the interior of the lipid bilayer. Agents incorporated within nanolipogels can be released into the milieu in a controlled fashion, for example, nanolipogels provide a means of achieving simultaneous sustained release of agents that differ widely in chemical composition and molecular weight. Additionally, nanolipogels can favorably modulate biodistribution. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 17/399544 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/127 (20130101) Original (OR) Class A61K 9/1271 (20130101) A61K 9/1273 (20130101) A61K 9/1277 (20130101) A61K 9/5153 (20130101) A61K 31/343 (20130101) A61K 38/1841 (20130101) A61K 38/2013 (20130101) A61K 47/24 (20130101) A61K 47/40 (20130101) A61K 47/58 (20170801) A61K 47/6849 (20170801) A61K 47/6937 (20170801) A61K 47/6951 (20170801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Peptides C07K 16/2812 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12156947 | Steinmetz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Nicole F. Steinmetz (San Diego, California); Jonathan Pokorski (San Diego, California) |
| ABSTRACT | A melt processed viral nanoparticle construct for delivery of virus or virus-like particles to a site of interest includes a degradable polymer matrix and a plurality of virus or virus-like particles encapsulated within the degradable polymer matrix. The nanoparticle construct upon administration to the site of interest providing a sustained release of the virus or virus-like particles and/or nanoparticles upon degradation of the polymer matrix. |
| FILED | Tuesday, May 23, 2023 |
| APPL NO | 18/200828 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0021 (20130101) A61K 9/5153 (20130101) A61K 9/5184 (20130101) Original (OR) Class A61K 2039/5258 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/18071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157126 | Cooks et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Zhenwei Wei (West Lafayette, Indiana) |
| ABSTRACT | The invention generally relates to systems and methods for synthesizing a reaction product and increasing yield of the same. In certain aspects, the invention provides a multi-mode reaction system in which in a first mode one or more valves of the system are configured to cause reagents to flow from one or more reagent reservoirs of the system through one or more components of the system to generate a reaction product; and in a second mode the one or more valves are configured to change flow within the system such that the one or more reagent reservoirs are isolated from a remainder of the system and the generated reaction product and any remaining reactants are recycled back through the multi-mode reaction system to increase a yield of the reaction product. |
| FILED | Wednesday, February 24, 2021 |
| APPL NO | 17/183691 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 7/02 (20130101) B01L 7/52 (20130101) Original (OR) Class B01L 2300/087 (20130101) B01L 2300/1894 (20130101) B01L 2400/0487 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157705 | Faber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Katherine T. Faber (Pasadena, California); Julia A. Kornfield (Pasadena, California); Noriaki Arai (Pasadena, California); Orland Bateman (Pasadena, California); Rustem F. Ismagilov (Pasadena, California) |
| ABSTRACT | Provided herein are methods for making a freeze-cast material having a internal structure, the methods comprising steps of: determining the internal structure of the material, the internal structure having a plurality of pores, wherein: each of the plurality of pores has directionality; and the step of determining comprises: selecting a temperature gradient and a freezing front velocity to obtain the determined internal structure based on the selected temperature gradient and the selected freezing front velocity; directionally freezing a liquid formulation to form a frozen solid, the step of directionally freezing comprising: controlling the temperature gradient and the freezing front velocity to match the selected temperature gradient and the selected freezing front velocity during directionally freezing; wherein the liquid formulation comprises at least one solvent and at least one dispersed species; and subliming the at least one solvent out of the frozen solid to form the material. |
| FILED | Monday, July 31, 2023 |
| APPL NO | 18/228369 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 67/0051 (20130101) B01D 67/0093 (20130101) B01D 67/00411 (20220801) B01D 69/02 (20130101) B01D 71/02 (20130101) B01D 71/024 (20130101) B01D 2323/081 (20220801) B01D 2325/021 (20130101) B01D 2325/26 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 35/56 (20240101) B01J 35/653 (20240101) B01J 35/657 (20240101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 38/007 (20130101) C04B 38/0038 (20130101) C04B 38/0054 (20130101) C04B 38/0093 (20130101) C04B 38/0605 (20130101) Original (OR) Class Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/14 (20130101) H01B 1/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157801 | Zhao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Xuanhe Zhao (Allston, Massachusetts); Hyunwoo Yuk (Cambridge, Massachusetts); Akihisa Inoue (Cambridge, Massachusetts) |
| ABSTRACT | Adhesion of conducting polymers on diverse insulating and conductive substrates via a hydrophilic adhesion layer, where one or more functional groups may be disposed between the substrate and the hydrophilic adhesion layer. Adhesion of the conducting polymers on the substrates is such that adhesion is maintained or substantially maintained in wet physiological environments. |
| FILED | Tuesday, May 05, 2020 |
| APPL NO | 16/866584 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/34 (20130101) A61L 27/34 (20130101) A61L 31/10 (20130101) A61L 31/10 (20130101) A61L 2420/02 (20130101) A61L 2420/08 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/122 (20130101) Original (OR) Class C08J 5/124 (20130101) C08J 2300/208 (20130101) Compositions of Macromolecular Compounds C08L 25/06 (20130101) C08L 25/06 (20130101) C08L 75/04 (20130101) C08L 75/04 (20130101) C08L 75/04 (20130101) C08L 101/12 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 9/00 (20130101) C09J 175/04 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 9/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157895 | Martin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (Ithaca, New York); Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | BOYCE THOMPSON INSTITUTE FOR PLANT RESEARCH, INC. (Ithaca, New York); CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Gregory B. Martin (Ithaca, New York); Ari Feder (Haifa, Israel); Samantha Mainiero (Ithaca, New York); Sarah Hind (Champaign, Illinois); Diana Carolina Mazo Molina (Ithaca, New York) |
| ABSTRACT | Embodiments of the disclosure are directed to compositions and methods for enhancing disease resistance in plants. One aspect of embodiments of the disclosure relates to a nucleic acid construct comprising a nucleic acid molecule comprising a Pseudomonas tomato race 1 (Ptr1) polynucleotide, a 5′ heterologous DNA promoter sequence, and a 3′ terminator sequence, wherein the nucleic acid molecule, the DNA promoter sequence, and the terminator sequence are operatively coupled to permit transcription of the nucleic acid molecule. Methods of imparting disease resistance to a plant and methods of identifying a candidate plant suitable for breeding that displays enhanced disease resistance are also disclosed. Embodiments of the disclosure also include plant cells, plants, and plant seeds including a heterologous Pseudomonas tomato race 1 (Ptr1) polynucleotide. |
| FILED | Tuesday, June 30, 2020 |
| APPL NO | 16/916757 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 1/00 (20130101) A01H 5/08 (20130101) A01H 6/82 (20180501) A01H 6/825 (20180501) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/00 (20130101) C12N 15/74 (20130101) C12N 15/82 (20130101) C12N 15/8279 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) C12Q 2600/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12158525 | Rishe |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Naphtali D. Rishe (Miami, Florida) |
| ASSIGNEE(S) | The Florida International University Board of Trustees (Miami, Florida) |
| INVENTOR(S) | Naphtali D. Rishe (Miami, Florida) |
| ABSTRACT | Systems and methods for generating ground-level terrain elevation models, preparing vector street data to assist in generating such models, and finding approximate elevation of any point using such terrain models are provided. Lidar data can be analyzed, and Lidar elevation values at roadway/street intersections can be used to determine a model of the ground-level elevation in an area or region. Outliers can be removed. The ground-level elevation at any point in the mapped area can be determined using elevation levels for nearby roadway intersections. |
| FILED | Friday, June 25, 2021 |
| APPL NO | 17/358795 |
| ART UNIT | 3658 — Material and Article Handling |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/89 (20130101) Original (OR) Class Electric Digital Data Processing G06F 16/29 (20190101) Image Data Processing or Generation, in General G06T 17/05 (20130101) Image or Video Recognition or Understanding G06V 20/13 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159193 | McDermott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Robert Francis McDermott (Madison, Wisconsin); Alexander M. Opremcak (Madison, Wisconsin) |
| ABSTRACT | The disclosed technology is directed to systems and methods for deterministic reset of superconducting qubit and cavity modes with a microwave photon counter. The system comprises a multiplicity of qubit-microwave photon counter pairs coupled by a qubit-qubit coupling. Each of the qubit-microwave photon counter pairs comprise a qubit circuit, a microwave photon counter circuit, and a resonant cavity coupling the qubit circuit and the microwave photon counter circuit. |
| FILED | Thursday, November 19, 2020 |
| APPL NO | 16/952598 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Pulse Technique H03K 19/195 (20130101) Electric solid-state devices not otherwise provided for H10N 60/12 (20230201) H10N 69/00 (20230201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159202 | Calderbank et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Arthur Robert Calderbank (Durham, North Carolina); Jingzhen Hu (Durham, North Carolina); Qingzhong Liang (Durham, North Carolina) |
| ABSTRACT | Technologies for performing error correction in a quantum circuit of a quantum computing system are disclosed. A quantum error correction code (QECC) is selected. The QECC is associated with a codespace. The quantum computing system identifies, based on one or more properties of the QECC, one or more diagonal physical gates in the quantum circuit that induces a target logical gate and preserves the codespace. The quantum computing system configures the quantum computing circuit to implement a quantum error correction protocol using the QECC and at least one of the identified diagonal physical gates. |
| FILED | Friday, January 27, 2023 |
| APPL NO | 18/102387 |
| ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1044 (20130101) Computer Systems Based on Specific Computational Models G06N 10/20 (20220101) G06N 10/40 (20220101) G06N 10/70 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159369 | Kudyshev et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Zhaxylyk A. Kudyshev (West Lafayette, Indiana); Demid Sychev (West lafayette, Indiana); Zachariah Olson Martin (West Lafayette, Indiana); Simeon I. Bogdanov (West Lafayette, Indiana); Xiaohui Xu (West Lafayette, Indiana); Alexander Kildishev (West Lafayette, Indiana); Alexandra Boltasseva (West Lafayette, Indiana); Vladimir Shalaev (West Lafayette, Indiana) |
| ABSTRACT | A method of providing super-resolved images of a photon emitting particle is disclosed, which includes providing a machine-learning (ML) platform, wherein the ML platform is configured to receive pixel-based sparse autocorrelation data and generate a predicted super-resolved image of a photon emitting particle, receiving photons from the photon emitting particle by two or more photon detectors, each generating an electrical pulse associated with receiving an incident photon thereon, generating sparse autocorrelation data from the two or more photon detectors for each pixel within an image area, and inputting the pixel-based sparse autocorrelation data to the ML platform, thereby generating a predicted super-resolved image of the imaging area, wherein the resolution of the super-resolved image is improved by √n as compared to a classical optical microscope limited by Abbe diffraction limit. |
| FILED | Wednesday, July 06, 2022 |
| APPL NO | 17/858722 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/0072 (20130101) Image Data Processing or Generation, in General G06T 3/4046 (20130101) G06T 3/4053 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159780 | Jarrold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| ASSIGNEE(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana) |
| INVENTOR(S) | Martin F. Jarrold (Bloomington, Indiana); Daniel Botamanenko (Bloomington, Indiana) |
| ABSTRACT | An electrostatic linear ion trap (ELIT) array includes a plurality of ion mirrors and a plurality of elongated charge detection cylinders each defining an axial passageway centrally therethrough, the ion mirrors and the charge detection cylinders arranged relative to one another such that each charge detection cylinder is positioned between a different respective pair of the ion mirrors with the respective axial passageways of each coaxial with one another, wherein the axial passageways of the ELITs are not coaxial with one another, means for selectively directing at least one ion into each of the plurality of ELITs, and means for controlling each of the ion mirrors in a manner which causes the at least one ion in at least two of the ELITs to become trapped therein and to simultaneously oscillate back and forth between the respective ion mirrors each time passing through the respective charge detection cylinder. |
| FILED | Tuesday, December 28, 2021 |
| APPL NO | 17/563457 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/022 (20130101) H01J 49/025 (20130101) H01J 49/0031 (20130101) H01J 49/0036 (20130101) H01J 49/406 (20130101) H01J 49/426 (20130101) H01J 49/4245 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12160185 | Mahbub et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF NORTH TEXAS (Dallas, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF NORTH TEXAS (Dallas, Texas) |
| INVENTOR(S) | Ifana Mahbub (Dallas, Texas); Russell Reid (Dallas, Texas); Pashupati R. Adhikari (Dallas, Texas); Nishat T. Tasneem (Dallas, Texas); Dipon K. Biswas (Dallas, Texas) |
| ABSTRACT | A motion sensor device comprises: a reverse electrowetting-on-dielectric (REWOD) generator configured to generate alternating current (AC) based on motion; a motion sensor configured to measure motion data; and a wireless motion sensor read-out circuit coupled to the REWOD generator and the motion sensor, the wireless motion sensor read-out circuit configured to transmit the motion data and operate on the AC from the REWOD generator. |
| FILED | Thursday, March 24, 2022 |
| APPL NO | 17/703870 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0004 (20130101) A61B 5/11 (20130101) A61B 2560/0214 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 13/00 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/06 (20130101) Electric Machines Not Otherwise Provided for H02N 1/08 (20130101) Original (OR) Class Amplifiers H03F 3/45264 (20130101) H03F 2203/45156 (20130101) H03F 2203/45526 (20130101) Coding; Decoding; Code Conversion in General H03M 1/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12160532 | Heinecke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Blocky, Inc. (Bozeman, Montana) |
| ASSIGNEE(S) | Blocky, Inc. (Bozeman, Montana) |
| INVENTOR(S) | Taylor Heinecke (Bozeman, Montana); David L. Millman (Bozeman, Montana); Mike P. Wittie (Bozeman, Montana) |
| ABSTRACT | A method for creating and maintaining immutability, agreement and availability of data including the steps of building an alternating structure of blocks and timestamp attestations; determining an order of blocks; determining which of the blocks are on a main chain; and using a trusted replication service to replicate all of the blocks, timestamp attestations, sequence attestations, and leaves of the Merkle trees. A computer program product comprising a storage device storing instructions in a non-transitory manner, which instructions cause the computing device to create and maintain immutability, agreement and availability of data according to the foregoing method. A computing device comprising a processing unit, memory or other storage device coupled to the processing unit, the memory or other storage device storage instructions, which cause the computing device to create and maintain immutability, agreement and availability of data according to the foregoing method. |
| FILED | Wednesday, November 30, 2022 |
| APPL NO | 18/072574 |
| ART UNIT | 2444 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/50 (20220501) Original (OR) Class H04L 9/0618 (20130101) H04L 9/3297 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 12157843 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Huai N. Cheng (Metairie, Louisiana); Michael K. Dowd (Metairie, Louisiana); Zhongqi He (New Orleans, Louisiana) |
| ABSTRACT | Disclosed herein are adhesive compositions containing a cottonseed protein and a catechol compound containing a carboxyl group, and optionally a carrier. Also disclosed are processes for producing an adhesive composition involving mixing a cottonseed protein and a catechol compound containing a carboxyl group, and optionally a carrier. |
| FILED | Friday, January 08, 2021 |
| APPL NO | 17/144329 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 37/1207 (20130101) B32B 2309/02 (20130101) B32B 2309/12 (20130101) B32B 2317/16 (20130101) Compositions of Macromolecular Compounds C08L 89/00 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 189/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157863 | Simonpietri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Simonpietri Enterprises LLC (Kailua, Hawaii) |
| ASSIGNEE(S) | SIMONPIETRI ENTERPRISES LLC (Kailua, Hawaii) |
| INVENTOR(S) | Marie-Joelle Simonpietri (Kailua, Hawaii); Zachary Wadas (Kailua, Hawaii) |
| ABSTRACT | Methods and systems for processing construction and demolition (C&D) materials to produce a product gas stream and/or electricity are disclosed herein. In some embodiments, the method comprises pre-processing C&D materials to produce a C&D feed, and processing the C&D feed to produce syngas. The C&D feed can comprise untreated wood, treated wood, paper and cardboard, yard waste, plastic, rubber, and/or foam. Processing the C&D feed can comprise gasifying the C&D feed, steam, and oxygen in a gasifier at a temperature of no more than 950° C. and/or a pressure of no more than 200 psi to produce syngas. |
| FILED | Friday, October 28, 2022 |
| APPL NO | 18/050950 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/02 (20130101) C01B 2203/04 (20130101) Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/78 (20130101) Original (OR) Class C10J 2300/092 (20130101) C10J 2300/0906 (20130101) C10J 2300/0946 (20130101) C10J 2300/1696 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 1/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157883 | Hay et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Bruce A Hay (Pasadena, California); Georg Oberhofer (Pasadena, California); Tobin William Ivy (Pasadena, California) |
| ABSTRACT | Described herein are embodiments relating to manipulation of populations and sex ratio in populations through DNA sequence modifications. |
| FILED | Thursday, May 03, 2018 |
| APPL NO | 15/970728 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/14 (20130101) C12N 5/16 (20130101) C12N 15/74 (20130101) C12N 15/80 (20130101) C12N 15/102 (20130101) Original (OR) Class C12N 15/905 (20130101) C12N 15/907 (20130101) C12N 15/8273 (20130101) C12N 15/8274 (20130101) C12N 15/8281 (20130101) C12N 15/8283 (20130101) C12N 15/8286 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 12157018 | Khokhlova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington); KONINKLIJKE PHILIPS N.V., A CORPORPORATION ORGANIZED AND EXISTING UNDER THE LAWS OF KINGDOM OF THE NETHERLANDS (Eindhoven, Netherlands) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); KONINKLIJKE PHILIPS N.V., A CORPORPORATION ORGANIZED AND EXISTING UNDER THE LAWS OF KINGDOM OF THE NETHERLANDS (Eindhoven, Netherlands) |
| INVENTOR(S) | Vera Khokhlova (Seattle, Washington); Michael R. Bailey (Seattle, Washington); Navid Farr (Seattle, Washington); Tatiana D. Khokhlova (Seattle, Washington); Wayne Kreider (Seattle, Washington); Adam D. Maxwell (Seattle, Washington); Ari Partanen (Andover, Massachusetts); Oleg A. Sapozhnikov (Seattle, Washington); George R. Schade (Seattle, Washington); Yak-Nam Wang (Seattle, Washington) |
| ABSTRACT | An example method includes generating an acoustic ultrasound wave that is focused at a focal point. The method further includes sequentially directing the focal point upon distinct portions of an object to form respective shock waves at the distinct portions of the object. The method further includes, via the respective shock waves, causing the distinct portions of the object to boil and form respective vapor cavities. The method further includes causing substantially uniform ablation of a region of the object that comprises the distinct portions. The substantially uniform ablation is caused via interaction of the respective shock waves with the respective vapor cavities. An example ablation system and an example non-transitory computer-readable medium, both related to the example method, are also disclosed. |
| FILED | Thursday, December 12, 2019 |
| APPL NO | 16/712680 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/22004 (20130101) A61B 2017/22007 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157179 | Courtright |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Zachary Stephen Courtright (Madison, Alabama) |
| ABSTRACT | Additive manufacturing systems and methods are disclosed. A housing includes a passageway having first and second open ends. A material is fed through the passageway and exits its second open end. A friction stir weld (FSW) bobbin pin tool is mounted in the housing with a radial edge of the pin tool's annular volume disposed adjacent to the second open end of the passageway. The annular volume is adapted to receive a substrate. The FSW bobbin pin tool is operable to be rotated so that the substrate and the material exiting the second open end of the passageway are plasticized in the annular volume for deposition onto the substrate. |
| FILED | Wednesday, July 12, 2023 |
| APPL NO | 18/351266 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 20/125 (20130101) B23K 20/1215 (20130101) Original (OR) Class B23K 20/1225 (20130101) B23K 20/1255 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12157584 | Backus et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Spencer Backus (Pasadena, California); Gregory S. Agnes (Pasadena, California); Russell G. Smith (Pasadena, California); Eric T. Sunada (Pasadena, California); Blair J. Emanuel (Pasadena, California); Rudranarayan M. Mukherjee (Pasadena, California); Samantha H. Glassner (Pasadena, California); Timothy P. Setterfield (Pasadena, California) |
| ABSTRACT | Pointing interfaces that can be used to assemble/disassemble instruments/payloads from a spacecraft/host are disclosed. The disclosed interfaces provide structural, communications, power, and fluid connections (for thermal control). Such interfaces also provide active and passive vibration isolation capability for precision pointing. They can further act as an interface to the launch vehicle for secondary delivery of the instrument/payload to the spacecraft. |
| FILED | Wednesday, April 27, 2022 |
| APPL NO | 17/731071 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/228 (20230801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 12156746 | Damaser et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); PARKER HANNIFIN CORPORATION (Cleveland, Ohio); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia); PARKER HANNIFIN CORPORATION (Cleveland, Ohio) |
| INVENTOR(S) | Margot S. Damaser (Cleveland, Ohio); Steve Majerus (Washington, District of Columbia); Hui Zhu (Cleveland, Ohio); Bradley C. Gill (Cleveland, Ohio); Ricardo Gonzalez (Cleveland, Ohio); Daniel Greene (Cleveland, Ohio); Joe Poliquin (Cleveland, Ohio); Glenn Craig (Cleveland, Ohio); Marie Lorentz (Cleveland, Ohio); Gino Banco (Cleveland, Ohio) |
| ABSTRACT | A sensing device can be used for ambulatory urodynamics. The sensing device can include an elongated outer housing constructed of flexible material that can curve within a patient's bladder. At least a portion of the outer housing can be filled with a non-compressible fluid. A flexible printed circuit board can be disposed within the outer housing to curve with the outer housing. The printed circuit board can include a pressure sensor, comprising a diaphragm, to collect pressure data; a microcontroller running control software; and a wireless transmitter to transmit the pressure data. A battery can be disposed within the outer housing and coupled to the printed circuit board. The flexible material of the outer housing is configured to be displaced by a pressure within the patient's bladder, the displacement is transmitted through the non-compressible fluid to the pressure sensor that provides the pressure data based on the displacement. |
| FILED | Tuesday, May 28, 2019 |
| APPL NO | 17/058783 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/07 (20130101) A61B 5/204 (20130101) A61B 5/205 (20130101) A61B 5/0538 (20130101) A61B 5/6874 (20130101) Original (OR) Class A61B 2560/066 (20130101) A61B 2560/0209 (20130101) A61B 2562/06 (20130101) A61B 2562/164 (20130101) A61B 2562/166 (20130101) A61B 2562/168 (20130101) A61B 2562/0247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12159403 | Madabhushi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio); University Hospitals Cleveland Medical Center (Cleveland, Ohio); The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States Government as Represented by The Department of Veteran Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Anant Madabhushi (Shaker Heights, Ohio); Cristian Barrera (Shaker Heights, Ohio); Mohammadhadi Khorrami (Cleveland Heights, Ohio); Prantesh Jain (Cleveland, Ohio); Afshin Dowlati (Solon, Ohio) |
| ABSTRACT | The present disclosure relates to a non-transitory computer-readable medium storing computer-executable instructions that, when executed, cause a processor to perform operations, including generating an imaging data set having both scan data and digitized biopsy data from a patient with small cell lung cancer (SCLC). Scan derived features are extracted from the scan data and biopsy derived features are extracted from the digitized biopsy data. A radiomic-pathomic risk score (RPRS) is calculated from one or more of the scan derived features and one or more of the biopsy derived features. The RPRS is indicative of a prognosis of the patient. |
| FILED | Monday, February 14, 2022 |
| APPL NO | 17/670817 |
| ART UNIT | 2635 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/7264 (20130101) A61B 5/7275 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 7/40 (20130101) G06T 2207/10081 (20130101) G06T 2207/20081 (20130101) G06T 2207/30024 (20130101) G06T 2207/30061 (20130101) G06T 2207/30096 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/40 (20180101) G16H 30/40 (20180101) G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 12158883 | Zeng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Hui Zeng (Fairfax, Virginia); Douglas R. Shumway (Gaithersburg, Maryland); Paul A. Geske (Raleigh, North Carolina); Wilairat Udomsawat (Fairfax, Virginia) |
| ABSTRACT | A computer-implemented method includes receiving data records from a plurality of different data sources, in which the data records include information regarding elements or components in one or more systems; consolidating the data records; extracting information from the consolidated data records to identify a plurality of nodes and connections between the plurality of nodes in the one or more systems; storing information identifying the plurality of nodes and the connections; and visually presenting the plurality of nodes and the connections in a user interface. |
| FILED | Tuesday, December 22, 2020 |
| APPL NO | 17/131080 |
| ART UNIT | 2168 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/252 (20190101) G06F 16/258 (20190101) G06F 16/2428 (20190101) Original (OR) Class G06F 16/9024 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 12160795 | Johnson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES POSTAL SERVICE (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey C. Johnson (Annapolis, Maryland); Leonetta J. Jackson (Dublin, California); Srinivasa R. Chappidi (Cupertino, California); Dongni S. Growney (Belmont, California); Bijai T. Nidhiri (Fremont, California); Danny Tan (San Francisco, California); Jini J. Thokalath (Foster City, California); Gang Yin (Fremont, California) |
| ABSTRACT | Techniques for tracking an evacuation of a location in an environment that utilizes physical tokens to prove physical presence at the location are presented. The techniques include receiving data representing of subordinates of an evacuation facilitator; receiving physical token based location status information for at least one of the subordinates, where the physical token based location status information is based on electronic readings of the physical tokens; determining based on the physical token based location status information, a physical presence status at the location for the at least one of the subordinates; receiving evacuation status information for each of the at least one of the subordinates that has a physical presence status that indicates a presence at the location; and recording the evacuation status information for each of the at least one of the subordinates that has a physical presence status that indicates a presence at the location. |
| FILED | Friday, September 01, 2023 |
| APPL NO | 18/459791 |
| ART UNIT | 2642 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Wireless Communication Networks H04W 4/12 (20130101) H04W 4/021 (20130101) H04W 4/029 (20180201) Original (OR) Class H04W 4/90 (20180201) H04W 12/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 12158410 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SOL INC. (Seoul, South Korea); Government of the United States of America, as Represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | SOL INC. (Seoul, South Korea); Government of the United States of America, as Represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| INVENTOR(S) | Jong Muk Lee (Seoul, South Korea); Darwin R. Reyes-Hernandez (Clarksburg, Maryland); Brian J. Nablo (Rockville, Maryland) |
| ABSTRACT | The present disclosure relates to a real-time quantification method of cell viability through a supravital dye uptake using a lens-free imaging system. The method includes a step of incubating a sample cell in a cell culture medium, steps of detecting light penetrating the cell culture medium and identifying a boundary region of the sample cell at a preset time interval based on the detected light, a step of staining the incubated sample cell with the supravital dye, a step of detecting intensity of light penetrating the cell culture medium at a preset time interval, a step of calculating absorbance of the sample cell included in the cell culture medium at a preset time interval based on the boundary region and the detected intensity of light and a step of analyzing a viability of the sample cell based on the calculated absorbance. |
| FILED | Monday, November 30, 2020 |
| APPL NO | 17/106961 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1433 (20240101) Original (OR) Class G01N 33/5041 (20130101) G01N 2015/1452 (20130101) G01N 2015/1472 (20130101) G01N 2015/1488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 12159446 | Fry |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Mark A. Fry (Marco Island, Florida) |
| ABSTRACT | Systems and methods of detecting a vortex made by a travelling object is disclosed. Techniques include positioning a media collector to capture a visual media file of the vortex. In some configurations, a graphic recognition algorithm and vortex similarity engine are used to determine whether a visual media file captured by a media collector contains a vortex. In some configurations, a computer may trigger an alert if a travelling object vortex is not expected to be in the visual media file. |
| FILED | Thursday, October 12, 2023 |
| APPL NO | 18/379235 |
| ART UNIT | 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/74 (20220101) G06V 10/761 (20220101) G06V 10/764 (20220101) Original (OR) Class G06V 10/7715 (20220101) G06V 20/52 (20220101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/182 (20130101) Traffic Control Systems G08G 5/003 (20130101) G08G 5/0017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 12157863 | Simonpietri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Simonpietri Enterprises LLC (Kailua, Hawaii) |
| ASSIGNEE(S) | SIMONPIETRI ENTERPRISES LLC (Kailua, Hawaii) |
| INVENTOR(S) | Marie-Joelle Simonpietri (Kailua, Hawaii); Zachary Wadas (Kailua, Hawaii) |
| ABSTRACT | Methods and systems for processing construction and demolition (C&D) materials to produce a product gas stream and/or electricity are disclosed herein. In some embodiments, the method comprises pre-processing C&D materials to produce a C&D feed, and processing the C&D feed to produce syngas. The C&D feed can comprise untreated wood, treated wood, paper and cardboard, yard waste, plastic, rubber, and/or foam. Processing the C&D feed can comprise gasifying the C&D feed, steam, and oxygen in a gasifier at a temperature of no more than 950° C. and/or a pressure of no more than 200 psi to produce syngas. |
| FILED | Friday, October 28, 2022 |
| APPL NO | 18/050950 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 3/02 (20130101) C01B 2203/04 (20130101) Production of Producer Gas, Water-gas, Synthesis Gas From Solid Carbonaceous Material, or Mixtures Containing These Gases; Carburetting Air or Other Gases C10J 3/78 (20130101) Original (OR) Class C10J 2300/092 (20130101) C10J 2300/0906 (20130101) C10J 2300/0946 (20130101) C10J 2300/1696 (20130101) Purifying or Modifying the Chemical Composition of Combustible Gases Containing Carbon Monoxide C10K 1/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Reconnaissance Office (NRO)
| US 12160240 | Wall et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL LABORATORIES, LLC (Malibu, California) |
| INVENTOR(S) | Walter S. Wall (Malibu, California); Randall L Kubena (Malibu, California) |
| ABSTRACT | A method and an apparatus for coupling two nonlinear resonators via a nonlinear element to generate phononic frequency combs. |
| FILED | Tuesday, April 11, 2023 |
| APPL NO | 18/133480 |
| ART UNIT | 2849 — Electrical Circuits and Systems |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/04 (20130101) H03B 5/32 (20130101) H03B 5/366 (20130101) Pulse Technique H03K 3/01 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 12159406 | Buckler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | ELUCID BIOIMAGING INC. (Boston, Massachusetts) |
| INVENTOR(S) | Andrew J. Buckler (Boston, Massachusetts); Kjell Johnson (Ann Arbor, Michigan); Xiaonan Ma (South Hamilton, Massachusetts); Keith A Moulton (Amesbury, Massachusetts); David S. Paik (Boston, Massachusetts) |
| ABSTRACT | Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data. |
| FILED | Tuesday, December 19, 2023 |
| APPL NO | 18/545542 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Electric Digital Data Processing G06F 18/24 (20230101) G06F 18/211 (20230101) G06F 18/2148 (20230101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 3/00 (20130101) G06T 5/73 (20240101) G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10048 (20130101) G06T 2207/10081 (20130101) G06T 2207/10088 (20130101) G06T 2207/10101 (20130101) G06T 2207/10104 (20130101) G06T 2207/10108 (20130101) G06T 2207/10132 (20130101) G06T 2207/20081 (20130101) G06T 2207/30096 (20130101) G06T 2207/30104 (20130101) Image or Video Recognition or Understanding G06V 10/25 (20220101) G06V 10/764 (20220101) G06V 20/69 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 12159156 | Yun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OKESTRO CO., LTD. (Seoul, South Korea) |
| ASSIGNEE(S) | OKESTRO CO., LTD. (Seoul, South Korea) |
| INVENTOR(S) | Ho Yeong Yun (Seoul, South Korea); Yoo Jong Lee (Seoul, South Korea); Chan Jae Lee (Seoul, South Korea); Young Gwang Kim (Seoul, South Korea); Min Jun Kim (Seoul, South Korea) |
| ABSTRACT | A virtual machine placement system for placing a plurality of virtual machines on a first physical server and a second physical server in order to efficiently operate a physical server in which the plurality of virtual machines are installed is provided. The physical server includes the first physical server and the second physical server. The virtual machine placement system includes a workload calculation module; a prediction module; a temperature prediction module; a schedule module; and a migration module. The schedule module calculates a placement schedule considering a predicted temperature of the physical server. |
| FILED | Thursday, December 23, 2021 |
| APPL NO | 17/560895 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) Original (OR) Class G06F 11/3058 (20130101) G06F 2009/4557 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 03, 2024.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-patents-20241203.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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