FedInvent™ Patents
Patent Details for Tuesday, June 06, 2006
This page was updated on Sunday, March 26, 2023 at 08:03 PM GMT
Department of Health and Human Services (HHS)
| US 07056493 | Kohn et al. |
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| ASSIGNEE(S) | Rutgers,The State University (New Brunswick, New Jersey) |
| INVENTOR(S) | Joachim B Kohn (Highland Park, New Jersey); Durgadas Bolikal (Edison, New Jersey); Sanyog M Pendharkar (Old Bridge, New Jersey) |
| ABSTRACT | Iodinated and/or brominated derivatives of aromatic dihydroxy monomers are prepared and polymerized to form radio-opaque polymers. The monomers may also be copolymerized with other dihydroxy monomers. The iodinated and brominated aromatic dihydroxy monomers can be employed as radio-opacifying, biocompatible non-toxic additives for other polymeric biomaterials. Radio-opaque medical implants and drug delivery devices for implantation prepared from the polymers of the present invention are also disclosed. |
| FILED | Thursday, October 23, 2003 |
| APPL NO | 10/691750 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056502 | Hildinger et al. |
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| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Markus Hildinger (Boston, Massachusetts); James M. Wilson (Gladwyne, Pennsylvania); Alberto Auricchio (Napoli, Italy) |
| ABSTRACT | A pseudotyped rAAV is described, which contains sequences derived from AAV5. A method for producing rAAV pseudotyped with AAV5 capsid is described in which the rep proteins of the serotype or any cross-reactive serotype of the AAV ITRs are utilized. A similar method may be provided to generate a pseudotyped rAAV in which minigenes carrying AAV5 ITRs are packaged in capsids of a heterologous AAV serotype. Also provided are pharmaceutical compositions containing the pseudotyped rAAV and methods of using them for gene delivery. |
| FILED | Monday, April 23, 2001 |
| APPL NO | 10/257961 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056503 | Rees et al. |
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| ASSIGNEE(S) | Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Riley Rees (Ann Arbor, Michigan); Jiyoun Kim (Ann Arbor, Michigan); Daniel Remick (Ann Arbor, Michigan); Belinda Adamson (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to devices, systems and methods for treating tumors. In particular, the present invention relates to enclosures housing cell-coated supports for promoting regression of tumors, such as cancerous tumors, papillomas, and warts. In preferred embodiments, the present invention provides methods of promoting tumor regression employing enclosures secreting therapeutic proteins. |
| FILED | Tuesday, September 25, 2001 |
| APPL NO | 09/962059 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056506 | Varner |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Judith A. Varner (Encinitas, California) |
| ABSTRACT | The present invention provides methods for reducing or inhibiting angiogenesis in a tissue, by contacting α5β1 integrin in the tissue with an agent that interferes with specific binding of the α5β1 integrin to a ligand expressed in the tissue; and methods of identifying angiogenesis in a tissue, by contacting the tissue with an agent that specifically binds α5β1 integrin, and detecting specific binding of the agent to α5β1 integrin associated with a blood vessel in the tissue. Also provided are methods of diagnosing a pathological condition characterized by angiogenesis in a tissue in an individual. The invention further provides methods of reducing or inhibiting angiogenesis in a tissue in an individual, by administering to the individual an agent that interferes with the specific binding of α5β1 integrin to a ligand expressed in the tissue; and methods of reducing the severity of a pathological condition associated with angiogenesis in an individual, by administering to the individual an agent that interferes with specific binding of α5β1 integrin to a ligand in a tissue associated with the pathological condition. The invention also provides methods of identifying an agent that reduces or inhibits angiogenesis associated with α5β1 integrin expression in a tissue by contacting a tissue exhibiting angiogenesis associated with α5β1 integrin expression with an agent, and detecting a reduction or inhibition of angiogenesis in the tissue. |
| FILED | Friday, July 05, 2002 |
| APPL NO | 10/190460 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056509 | Thorpe et al. |
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| ASSIGNEE(S) | Board of Regents The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Philip E. Thorpe (Dallas, Texas); Rolf A. Brekken (Seattle, Washington) |
| ABSTRACT | Disclosed are antibodies that specifically inhibit VEGF binding to only one (VEGFR2) of the two VEGF receptors. The antibodies effectively inhibit angiogenesis and induce tumor regression, and yet have improved safety due to their specificity. The present invention thus provides new antibody-based compositions, methods and combined protocols for treating cancer and other angiogenic diseases. Advantageous immunoconjugate and prodrug compositions and methods using the new VEGF-specific antibodies are also provided. |
| FILED | Monday, February 24, 2003 |
| APPL NO | 10/373561 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/145.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056514 | Mayo et al. |
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| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Kevin H. Mayo (Minneapolis, Minnesota); Thomas R. Hoye (St. Paul, Minnesota); Carolee Flader Lavey (New Providence, New Jersey) |
| ABSTRACT | Partial peptide mimetics and methods of making and using, wherein the partial peptide mimetics have a first amino acid sequence comprising ANIKLSVQMKL (SEQ ID NO:8), a homolog thereof, or a segment of SEQ ID NO:8 or a homolog thereof, a second amino acid sequence comprising IIVKLND (SEQ ID NO:2), a homolog thereof, or a segment of SEQ ID NO:2 or a homolog thereof, and a β-turn inducing scaffold bonded between the first and second amino acid sequences. |
| FILED | Thursday, February 20, 2003 |
| APPL NO | 10/371406 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056517 | Smith et al. |
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| ASSIGNEE(S) | The Forsyth Institute (Boston, Massachusetts) |
| INVENTOR(S) | Daniel J. Smith (Natick, Massachusetts); Martin A. Taubman (Newtonville, Massachusetts) |
| ABSTRACT | Vaccine compositions and immunogenic compositions are described which are glucosyltransferase subunit vaccines for dental caries and which contain at least one peptide which corresponds to a sequence of glucosyltransferase containing aspartate 413, an equivalent of aspartate 413, aspartate 451, an equivalent of aspartate 451, aspartate 562, an equivalent of aspartate 562, aspartate 567, an equivalent of aspartate 567, histidine 561, an equivalent of histidine 561, tryptophan 491, an equivalent of tryptophan 491, glutamate 489, an equivalent of glutamate 489, arginine 449, an equivalent of arginine 449, or combinations thereof. These subunit vaccines elicit antibodies which protect an immunized mammal from dental caries. Methods of provoking an immune response to intact glucosyltransferase are also described. |
| FILED | Tuesday, March 09, 2004 |
| APPL NO | 10/797302 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/190.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056524 | Boucher, Jr. |
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| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Richard C. Boucher, Jr. (Chapel Hill, North Carolina) |
| ABSTRACT | A method of hydrating nasal airway surfaces in a subject in need of such treatment comprises topically applying a sodium channel blocker to a nasal airway surface of the subject in an amount effective to inhibit the reabsorption of water by the surface. The channel blocker may be a pyrazinoylguanidine sodium channel blocker, such as benzamil, phenamil, amiloride, or a pharmaceutically acceptable salts thereof. The method may further comprise the step of topically applying a P2Y2 receptor agonist to a nasal airway surface of the subject in an amount effective to stimulate chloride secretion by the nasal airway surface. In a preferred embodiment, the sodium channel blocker is a covalent conjugate of a pyrazinoylguanidine sodium channel blocker and a non-absorbable carrier moiety (e.g., albumin, polyethylene glycol). Such compounds may also be administered to other mucosal surfaces where it is desired to inhibit the reabsorption of water. |
| FILED | Tuesday, February 20, 2001 |
| APPL NO | 09/789256 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/434 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056533 | Chudzik et al. |
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| ASSIGNEE(S) | SurModics, Inc. (Eden Prairie, Minnesota) |
| INVENTOR(S) | Stephen J. Chudzik (St. Paul, Minnesota); Terrence P. Everson (Eagan, Minnesota); Richard A. Amos (St. Anthony, Minnesota) |
| ABSTRACT | A coating composition, in both its uncrosslinked and crosslinked forms, for use in delivering a medicament from the surface of a medical device positioned in vivo. Once crosslinked, the coating composition provides a gel matrix adapted to contain the medicament in a form that permits the medicament to be released from the matrix in a prolonged, controlled, predictable and effective manner in vivo. A composition includes a polyether monomer, such as an alkoxy poly(alkylene glycol), a carboxylic acid-containing monomer, such as (meth)acrylic acid, a photoderivatized monomer, and a hydrophilic monomer such as acrylamide. |
| FILED | Monday, July 09, 2001 |
| APPL NO | 09/901425 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/486 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056656 | Rana et al. |
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| ASSIGNEE(S) | University of Medicine and Dentistry of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Tariq M. Rana (Shrewsbury, Massachusetts); Natarajan Tamilarasu (Highland Park, New Jersey); Ikramul Huq (Edison, New Jersey) |
| ABSTRACT | This invention relates to the use of oligourea molecules to specifically inhibit protein-nucleic acid interactions. In particular, it provides an oligourea molecule that competes with the Tat molecule for the TAR RNA of HIV-1. Also provided is a method specifically inhibiting protein-nucleic and interactions, and kits. |
| FILED | Tuesday, January 25, 2000 |
| APPL NO | 09/889982 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056661 | Korlach et al. |
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| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jonas Korlach (Ithaca, New York); Watt W. Webb (Ithaca, New York); Michael Levene (Ithaca, New York); Stephen Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Mathieu Foquet (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined. |
| FILED | Wednesday, May 17, 2000 |
| APPL NO | 09/572530 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056662 | Hotamisligil |
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| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Gokhan S. Hotamisligil (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides compositions and methods of inhibiting Mal1 expression or function to treat lipid metabolisms disorders. |
| FILED | Friday, February 16, 2001 |
| APPL NO | 09/788074 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056663 | Dairkee et al. |
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| ASSIGNEE(S) | California Pacific Medical Center (San Francisco, California) |
| INVENTOR(S) | Shanaz H. Dairkee (Orinda, California); Zheng Li (Hayward, California) |
| ABSTRACT | Methods of determining the likelihood of the re-occurrence of tumors and of determining the aggressiveness of post-surgical treatment are provided which rely on analysis of a loss of heterogeneity at the particular chromosomal locus 3p24.3. Loss of expression or hypermethylation of the thyroid hormone receptor β1 gene is also predictive of an increased re-occurrence of tumors. |
| FILED | Friday, March 23, 2001 |
| APPL NO | 09/816460 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056676 | Korlach et al. |
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| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jonas Korlach (Ithaca, New York); Watt W. Webb (Ithaca, New York); Michael Levene (Ithaca, New York); Stephen Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Mathieu Foquet (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined. |
| FILED | Thursday, December 16, 2004 |
| APPL NO | 11/015138 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056688 | Herz et al. |
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| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Joachim Herz (Dallas, Texas); Michael Gotthardt (Dallas, Texas) |
| ABSTRACT | The invention provides methods and compositions for inducing and detecting signal transduction through LDL receptors, including specifically detecting a stress that alters a functional interaction of a low density lipoprotein (LDL) receptor binding polypeptide with an LDL receptor interaction domain, by (a) introducing a predetermined stress into a system which provides a physical interaction of an LDL receptor binding polypeptide with an LDL receptor intracellular binding polypeptide interaction domain, whereby the system provides a stress-biased interaction of the binding polypeptide and the interaction domain, wherein the absence of the stress, the system provides a unbiased interaction of the binding polypeptide and the interaction domain; and (b) detecting the stress-biased interaction of the binding polypeptide and the interaction domain, wherein the binding polypeptide is selected from SEMCAP-1, JIP-1, PSD-95, JIP-2, Talin, OMP25, CAPON, PIP4,5 kinase, Na channel brain 3, Mint1, ICAP-1 and APC subunit 10. |
| FILED | Thursday, August 01, 2002 |
| APPL NO | 10/211962 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056689 | Lorence et al. |
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| ASSIGNEE(S) | Wellstat Biologics Corporation (Gaithersburg, Maryland) |
| INVENTOR(S) | Robert M. Lorence (Rockville, Maryland); Kirk W. Reichard (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention provides a method of treating cancer in a mammal comprising administering to the mammal an effective amount of virus, particularly Newcastle Disease Virus or other Paramyxovirus. The invention also provides a method of treating cancer in a mammal comprising administering such viruses to the mammal in combination with another agent such as a chemotherapeutic compound, immunoadjuvant, cytokine, or immunosuppressive agent. The invention further provides a method of detecting cancer cells in a mammal using Paramyxovirus as an imaging agent and as an indicator of cancer cell growth in the mammal. The invention further provides genetically engineered Paramyxoviruses, and kits containing the viral compositions disclosed by the invention. |
| FILED | Thursday, June 16, 1994 |
| APPL NO | 08/260536 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056693 | Duesbery et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Nicholas Duesbery (Grand Rapids, Michigan); Craig Webb (Rockford, Michigan); Stephen Leppla (Bethesda, Maryland); George Vande Woude (Ada, Michigan) |
| ABSTRACT | The present invention relates to in vitro and ex vivo methods of screening for modulators, homologues, and mimetics of lethal factor mitogen activated protein kinase kinase (MAPKK) protease activity, as well as methods of treating cancer by administering LF to transformed cells. |
| FILED | Friday, April 22, 2005 |
| APPL NO | 11/112137 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056694 | Papadopoulos et al. |
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| ASSIGNEE(S) | Georgetown University (Washington, District of Columbia) |
| INVENTOR(S) | Vassilios Papadopoulos (North Potomac, Maryland); Hua Li (North Potomac, Maryland) |
| ABSTRACT | The present invention relates to nucleic acids encoding peripheral-type benzodiazepine receptor (PBR)-associated proteins (PAPs), and nucleic acids that hybridize or are variant of nucleic acids encoding the peripheral-type benzodiazepine receptor (PBR)-associated proteins (PAPs), which are capable of encoding proteins that regulate the function of PBRs affecting both steroid biosynthesis and mediating cholesterol delivery as well as other PBR-mediated functions. |
| FILED | Wednesday, August 11, 1999 |
| APPL NO | 09/762594 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056700 | Galen |
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| ASSIGNEE(S) | University of Maryland (Baltimore, Maryland) |
| INVENTOR(S) | James E. Galen (Owings Mills, Maryland) |
| ABSTRACT | The disclosure below provides a protein export system for efficiently producing recombinant protein from a host cell. In a preferred embodiment, the protein export system utilizes protein export machinery endogenous to the host bacterium into which the protein export system vector is introduced. |
| FILED | Friday, November 23, 2001 |
| APPL NO | 09/993292 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056713 | Hershfield et al. |
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| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Michael Hershfield (Durham, North Carolina); Susan J. Kelly (Chapel Hill, North Carolina) |
| ABSTRACT | The present invention relates, in general, to urate oxidase (uricase) proteins and nucleic acid molecules encoding same. In particular, the invention relates to uricase proteins which are particularly useful as, for example, intermediates for making improved modified uricase proteins with reduced immunogenicity and increased bioavailability. |
| FILED | Thursday, August 05, 1999 |
| APPL NO | 09/762097 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056731 | Thomae et al. |
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| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Bianca A. Thomae (Rochester, Minnesota); Eric D. Wieben (Rochester, Minnesota); Richard M. Weinshilboum (Rochester, Minnesota) |
| ABSTRACT | Isolated sulfotransferase nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as sulfotransferase allozymes. Methods for determining if a mammal is predisposed to a heart condition or cancer also are described. |
| FILED | Friday, June 21, 2002 |
| APPL NO | 10/177570 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/320.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056734 | Egan et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services, NIH (Washington, District of Columbia) |
| INVENTOR(S) | Josephine Egan (Baltimore, Maryland); Riccardo Perfetti (Washington, District of Columbia); Antonino Passaniti (White Hall, Maryland); Nigel Greig (Silver Spring, Maryland); Harold Holloway (Middle River, Maryland); Joel Habener (Newton Centre, Massachusetts); Doris Stoffers (Moorestown, New Jersey) |
| ABSTRACT | The present invention relates to a population of insulin producing cells made by a process comprising contacting non-insulin producing cells with a growth factor selected from the group consisting of GLP-1 or Exendin-4, growth factors having amino acid sequences substantially homologous to GLP-1 or Exendin-4, and fragmets thereof. The present invention also relates to methods of differentiating non-insulin producing cells into insulin producing cells and of enriching a population of cells for insulin-producing cells. The present invention also relates to methods of treating diabetes. |
| FILED | Tuesday, August 10, 1999 |
| APPL NO | 09/762538 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056738 | Prockop et al. |
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| ASSIGNEE(S) | Tulane University (New Orleans, Louisiana); Philadelphia Heath and Education Corporation (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Darwin J. Prockop (New Orleans, Louisiana); David C. Colter (Philadelphia, Pennsylvania); Ichiro Sekiya (New Orleans, Louisiana) |
| ABSTRACT | Marrow stromal cells (MSCS) are adult stem cells from bone marrow that can differentiate into multiple non-hematopoietic cell lineages. Colonies of human MSCs were shown to contain both small, rapidly self-renewing stem cells (RS cells) and large, more mature cells (mMSCs). Samples enriched for RS cells had a greater potential for multipotential differentiation than samples enriched for mMSCs. Also, RS cells have a series of surface epitopes and expressed proteins that can be used to differentiate RS cells from mMSCs. The results suggest that it will be important to distinguish the two major sub-populations of MSCs in defining their biology and their potentials for cell and gene therapy. |
| FILED | Friday, March 23, 2001 |
| APPL NO | 09/816182 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/372 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056894 | Sauve et al. |
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| ASSIGNEE(S) | Albert Einstein College of Medicine of Yeshiva University (Bronx, New York) |
| INVENTOR(S) | Anthony A. Sauve (Bronx, New York); Vern L. Schramm (New Rochelle, New York) |
| ABSTRACT | The present invention provides compounds having the formula: wherein A is chosen from a nitrogen-, oxygen-, or sulfur-linked aryl, alkyl, cyclic, or heterocyclic group; both B and C are hydrogen, or either B or C is a halogen, amino, or thiol group and the other of B or C is hydrogen; and D is a primary alcohol, a hydrogen, or an oxygen, nitrogen, carbon, or sulfur linked to phosphate, a phosphoryl group, a pyrophosphoryl group, or adenosine monophosphate through a phosphodiester or carbon-, nitrogen-, or sulfur-substituted phosphodiester bridge, or to adenosine diphosphate through a phosphodiester or carbon-, nitrogen-, or sulfur-substituted pyrophosphodiester bridge. The present invention also provides pharmaceutical compositions containing the above compounds, methods of using the above compounds as pharmaceuticals, and processes for preparing the above compounds. Also provided are methods for inhibiting an ADP-ribosyl transferase, ADP-ribosyl cyclase, or ADP-ribosyl hydrolase enzyme, and methods for treating a disease or condition associated with an ADP-ribosyl transferase, ADP-ribosyl cyclase, or ADP-ribosyl hydrolase enzyme in a subject in need of treatment thereof. |
| FILED | Friday, January 04, 2002 |
| APPL NO | 10/038760 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/42 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056904 | DeLuca et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Hector F. DeLuca (Deerfield, Wisconsin); Rafal R. Sicinski (Warsaw, Poland) |
| ABSTRACT | A method of modifying or altering the structure of a 1α-hydroxylated vitamin D compound to increase its biological activity by altering the conformational equilibrium of the A-ring to favor a chair conformation that presents the 1α-hydroxyl in the axial orientation. This is accomplished by either locking the A-ring chair conformation in a geometry having an axially orientated 1α-hydroxyl, or by the addition of one or more substituents to the A-ring which interact with other substituents in the molecule or on the A-ring to provide a driving force to the A-ring to adopt a chair conformation which presents the 1α-hydroxyl in the axial orientation. |
| FILED | Friday, March 18, 2005 |
| APPL NO | 11/083577 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/167 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056908 | Yuspa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Stuart H. Yuspa (Bethesda, Maryland); Andrzej Dlugosz (Rockville, Maryland); Henry Hennings (Gaithersburg, Maryland); James Strickland (Rockville, Maryland) |
| ABSTRACT | Pharmaceutical compositions and methods for treating epithelial cancers and precancerous lesions employ indole carbazole compounds, such as staurosporine. Compositions containing these compounds are administered to a patient in an effective amount and may be administered topically. |
| FILED | Tuesday, May 27, 2003 |
| APPL NO | 10/445251 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/211.80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056911 | Rosowsky |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Dana-Farber Cancer Institute (Boston, Massachusetts) |
| INVENTOR(S) | Andre Rosowsky (Needham, Massachusetts) |
| ABSTRACT | The invention relates to pharmaceutically active compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention and particularly useful for the treatment or prophylaxis of diseases associated with parasitic infection such as pneumocystis pneumonia, toxoplasmosis, cryptosporidiosis, leischmaniasis and malaria. |
| FILED | Tuesday, January 25, 2000 |
| APPL NO | 09/890112 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/217 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056927 | Guo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Neurocrine Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Zhiqiang Guo (San Diego, California); Yongsheng Chen (San Diego, California); Dongpei Wu (San Diego, California); Chen Chen (San Diego, California); Warren Wade (San Diego, California); Wesley J. Dwight (San Diego, California); Charles Q. Huang (San Diego, California); Fabio C. Tucci (San Diego, California) |
| ABSTRACT | GnRH receptor antagonists are disclosed that have utility in the treatment of a variety of sex-hormone related conditions in both men and women. The compounds of this invention have the structure: wherein R1a, R1b, R1c, R2a, R2b, R3, R4, R5, R6 and X are as defined herein, including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof. Also disclosed are compositions containing a compound of this invention in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for antagonizing gonadotropin-releasing hormone in a subject in need thereof. |
| FILED | Tuesday, July 06, 2004 |
| APPL NO | 10/885491 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/274 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056945 | Poulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Thomas Poulos (Irvine, California); Huiying Li (Irvine, California); Mack Flinspach (Lake Forest, California) |
| ABSTRACT | Compositions, prodrugs and methods for inhibiting neural Nitric Oxide Synthase (nNOS). By inhibiting nNOS, the compounds, prodrugs and methods of the presnet invention are useable to treat or prevent disorders in human or veterinary patients that are caused, mediated or agrevated by Nitric Oxide within the body. |
| FILED | Tuesday, June 17, 2003 |
| APPL NO | 10/463213 |
| ART UNIT | 1614 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/428 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057035 | Wentland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Mark P. Wentland (Menands, New York); Rongliang Lou (Cheshire, Connecticut) |
| ABSTRACT | A process for converting an aryl triflate, heteroaryl triflate, aryl halide or heteroaryl halide to an N-hydroxysuccinimido ester is disclosed. The process involves reacting the triflate or halide with carbon monoxide and N-hydroxysuccinimide in a solvent in the presence of a palladium catalyst and a base. |
| FILED | Friday, January 14, 2005 |
| APPL NO | 11/035750 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 540/477 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057038 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Brandeis University (Waltham, Massachusetts) |
| INVENTOR(S) | Li Deng (Waltham, Massachusetts); Jianfeng Hang (Waltham, Massachusetts); Liang Tang (Waltham, Massachusetts) |
| ABSTRACT | One aspect of the present invention relates to a method for the kinetic resolution of racemic and diastereomeric mixtures of chiral compounds. The critical elements of the method are: a non-racemic chiral tertiary-amine-containing catalyst; a racemic or diastereomeric mixture of a chiral substrate, e.g., a cyclic carbonate or cyclic carbamate; and a nucleophile, e.g., an alcohol, amine or thiol. A preferred embodiment of the present invention relates to a method for achieving the kinetic resolution of racemic and diastereomeric mixtures of derivatives of α- and β-amino, hydroxy, and thio carboxylic acids. In certain embodiments, the methods of the present invention achieve dynamic kinetic resolution of a racemic or diastereomeric mixture of a substrate, i.e., a kinetic resolution wherein the yield of the resolved enantiomer or diastereomer, respectively, exceeds the amount present in the original mixture due to the in situ equilibration of the enantiomers or diastereomers under the reaction conditions prior to the resolution step. |
| FILED | Wednesday, May 26, 2004 |
| APPL NO | 10/854737 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Organic compounds 544/97 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057387 | Duensing et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Invivo Corporation (Orlando, Florida) |
| INVENTOR(S) | G. Randy Duensing (Gainesville, Florida); Steve Varosi (Gainesville, Florida); Scott B. King (Gainesville, Florida) |
| ABSTRACT | The subject invention pertains to a method and apparatus for enhanced multiple coil imaging. The subject invention is advantageous for use in imaging devices, such as MRIs where multiple images can be combined to form a single composite image. In one specific embodiment, the subject method and apparatus utilize a novel process of converting from the original signal vector in the time domain to allow the subject invention to be installed in-line with current MRI devices. |
| FILED | Tuesday, June 18, 2002 |
| APPL NO | 10/174843 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 07055278 | Davis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Terry L. Davis (Yuma, Arizona) |
| ABSTRACT | A portable cannon tube cleaning system that includes a trailer designed to be pulled to the field site of a cannon tube to be cleaned; a mechanism securely mounted to the floor of the trailer for providing vertical height adjustment; a main cleaner chassis assembly securely mounted to the height adjustment mechanism so that when the height adjustment mechanism is actuated the height of the main cleaner chassis assembly may be adjusted to be in line with the cannon tube to be cleaned; and a mechanism contained in the main cleaner chassis assembly for hauling a cleaning brush assembly through the cannon tube for as many cycles as required to adequately clean the tube for inspections. |
| FILED | Friday, September 05, 2003 |
| APPL NO | 10/655072 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Firearms 042/95 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07055422 | Dindl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Frank Dindl (Newton, New Jersey); Sergio Aponte (Paterson, New Jersey) |
| ABSTRACT | An improved Barrett anti-armor gun that is modified to function from the open bolt with advanced primer ignition, wherein the forward momentum of the recoiling masses at the moment of firing offset a significant portion of the recoil impulse from firing. The modification reduces the recoil energy absorbed by the shooter. |
| FILED | Tuesday, September 07, 2004 |
| APPL NO | 10/711263 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/194 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07055434 | Thompson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Don Thompson (Ridgecrest, California); George N. Hennings (Ridgecrest, California) |
| ABSTRACT | A method of using electrically initiated primer systems that rely on vaporizing a thin metallic film which is either coated on a non-conductive insulator component or is a malleable thin film or strip secured to the inner surface of a primer cup assembly to ignite an environmentally safe MIC composition. |
| FILED | Wednesday, June 09, 2004 |
| APPL NO | 10/868458 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/204 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07055437 | Robinson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Charles H. Robinson (Silver Spring, Maryland); Robert H. Wood (Laurel, Maryland); Mark R. Gelak (Columbia, Maryland); David Hollingsworth (Fallon, Nevada) |
| ABSTRACT | A microscale firetrain for a safe and arm device having a safe position and an armed position, the firetrain including an input explosive column having a longitudinal axis; a transfer charge having a longitudinal axis and first and second ends and movable from a safe position to an armed position; a receptor charge having a longitudinal axis that is non-collinear with and substantially parallel to the longitudinal axis of the input explosive column; wherein, in the safe position, the transfer charge is remote from both the input explosive column and the receptor charge; and wherein, in the armed position, the input explosive column is adjacent the first end of the transfer charge to thereby initiate the transfer charge, the longitudinal axis of the input explosive column is substantially perpendicular to the longitudinal axis of the transfer charge, the second end of the transfer charge is adjacent the receptor charge to thereby initiate the receptor charge and the longitudinal axis of the receptor charge is substantially perpendicular to the longitudinal axis of the transfer charge. |
| FILED | Wednesday, September 29, 2004 |
| APPL NO | 10/711632 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/222 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07055438 | Manole et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Leon R. Manole (Great Meadows, New Jersey); Stewart Gilman (Budd Lake, New Jersey); Erinn Harbeck McCarthy (Randolph, New Jersey); Steven Kelley (Stanhope, New Jersey); Remi Chian (Brooklyn, New York); Melissa Wanner (Delaware Water Gap, Pennsylvania); Ernest Logsdon (Newton, New Jersey) |
| ABSTRACT | A flameless tracer/marker provides heat mark chemicals with optional chemlucents chemicals that can be carried and delivered by a projectile to mark a target. This marking payload may be carried by small, medium and large caliber projectiles that are part of ammunition items including 20 and 40 mm grenade launched, 90 mm, 105 and 120 mm tank, 60, 81 and 120 mm mortar and 105 and 155 artillery ammunition. This ammunition is gun launched and the projectiles can provide a heat trace to the target and/or upon impact with the target the projectile breaks or shatters and leaves a heat signature on the target for up to several hours. Included with these heat chemicals may be optional chemlucents. This heat mark may be placed into a lethal and non-lethal projectile. This allows heavy and light armor targets, vehicles, buildings and personnel to be marked without extensive damage to the target and without seriously injuring a person. The target may now be heat marked and chemlucent marked. |
| FILED | Tuesday, December 02, 2003 |
| APPL NO | 10/707272 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/513 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07055986 | Littleton |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Roy T. Littleton (Woodbridge, Virginia) |
| ABSTRACT | An apparatus for emulating various known night sky illumination conditions. The apparatus comprises a plurality of electrically-powerable LEDs which are disposed in an array and have respective spectral curves centered at different wavelengths in the visible to the short wave infrared wavebands, and means for fixing the temperatures of the LEDs to avoid temperature-induced changes in their spectral curves. Additionally, the apparatus includes means for varying the light intensities of the individual LEDs so that the combination of their spectral curves matches the spectrum of the known night sky illumination condition to be emulated, and means for regulating the total amount of light collected from the array so that the cumulative spectrum has the same intensity as the known night sky illumination condition to be emulated. |
| FILED | Friday, March 05, 2004 |
| APPL NO | 10/792850 |
| ART UNIT | 2875 — Optics |
| CURRENT CPC | Illumination 362/231 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056071 | Kister et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Wendell Kister (Fillmore, California); Gregory V. Brodbeck (Camarillo, California); Ronald L. Spencer (Camarillo, California) |
| ABSTRACT | An apparatus for repairing a pair of non-conforming bushings on the M89E1 Declutching Ammo feeder for the M197 machine gun. The apparatus includes a central body and a pair of large drill plates which allows a user to drill out the non-conforming bushings from the ammo feeder. The user then press fits replacement bushings into the ammo feeder. The apparatus also includes a pair of small drill plates which allows the user to drills pin mounting holes into the replacement bushings. |
| FILED | Tuesday, September 28, 2004 |
| APPL NO | 10/956519 |
| ART UNIT | 3722 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Cutting by use of rotating axially moving tool 48/115.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056085 | Ponziani |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Robert Louis Ponziani (West Chester, Ohio) |
| ABSTRACT | A vane assembly includes a vane having a main axis, a first passageway within the vane substantially parallel to the main axis, and a second passageway aligned with the first passageway. The vane has a window portion between the first passageway and the second passageway. The vane assembly also includes a sensor inserted in the first passageway and having a portion held in place in the second passageway, wherein a portion of the sensor is exposed in the window portion of the vane. |
| FILED | Friday, July 09, 2004 |
| APPL NO | 10/888249 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/118 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056514 | Mayo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Kevin H. Mayo (Minneapolis, Minnesota); Thomas R. Hoye (St. Paul, Minnesota); Carolee Flader Lavey (New Providence, New Jersey) |
| ABSTRACT | Partial peptide mimetics and methods of making and using, wherein the partial peptide mimetics have a first amino acid sequence comprising ANIKLSVQMKL (SEQ ID NO:8), a homolog thereof, or a segment of SEQ ID NO:8 or a homolog thereof, a second amino acid sequence comprising IIVKLND (SEQ ID NO:2), a homolog thereof, or a segment of SEQ ID NO:2 or a homolog thereof, and a β-turn inducing scaffold bonded between the first and second amino acid sequences. |
| FILED | Thursday, February 20, 2003 |
| APPL NO | 10/371406 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/185.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056675 | Samuelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Lynne A. Samuelson (Marlborough, Massachusetts); Ferdinando Bruno (Andover, Massachusetts); Susan Tripathy, legal representative (Acton, Massachusetts); Ramaswamy Nagarajan (Lowell, Massachusetts); Jayant Kumar (Westford, Massachusetts); Wei Liu (Lowell, Massachusetts) |
| ABSTRACT | A conductive polymer is formed enzymatically in the presence of a polynucleotide template. The method includes combining at least one redox monomer with a polynucleotide template and a redox enzyme, such as horseradish peroxidase, to form a reaction mixture. The monomer aligns along the template before or during the polymerization. Therefore, the polynucleotide template thereby affects the molecular weight and conformation of the conductive polymer. When the conductive polymer is complexed to a polynucleotide duplex, the conformation of the polynucleotide duplex can be modulated by changing the oxidation state of the conductive polymer. |
| FILED | Tuesday, October 05, 2004 |
| APPL NO | 10/958907 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056683 | Ting |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Alice Y. Ting (Allston, Massachusetts) |
| ABSTRACT | The invention provides fusion protein reporter molecules that can be used to monitor protein modifications (e.g., histone modifications) in living cells, and methods of using the fusion reporter molecules for diagnosing protein-modification-associated disorders (e.g. histone-modification-associated disorders). The invention also provides methods of using the fusion protein reporters to identify candidate pharmaceutical agents that effect protein modification in cells and tissues, thus permitting identification of candidate pharmaceutical agents for treatment of protein-modification-associated disorders. |
| FILED | Tuesday, August 05, 2003 |
| APPL NO | 10/634740 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
07056757 — Methods of forming oxide masks with submicron openings and microstructures formed thereby
| US 07056757 | Ayazi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Farrokh Ayazi (Atlanta, Georgia); Reza Abdolvand (Atlanta, Georgia); Siavash P. Anaraki (Smyrna, Georgia) |
| ABSTRACT | Processing techniques are disclosed for batch fabrication of microstructures comprising an oxide mask on a substrate with submicron openings formed therein, and microstructures having deep-submicron, high aspect-ratio etched trenches, using conventional optical photolithography. Exemplary high aspect-ratio etched-trench microstructures that may be produced include single crystal resonators and sensors. |
| FILED | Monday, November 22, 2004 |
| APPL NO | 10/996683 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/48 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056815 | Weng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Xiaojun Weng (Ann Arbor, Michigan); Rachel S. Goldman (Ann Arbor, Michigan) |
| ABSTRACT | A method for forming a semi-conductor material is provided that comprises forming a donor substrate constructed of GaAs, providing a receiver substrate, implanting nitrogen into the donor substrate to form an implanted layer comprising GaAs and nitrogen. The implanted layer is bonded to the receiver substrate and annealed to form GaAsN and nitrogen micro-blisters in the implanted layer. The micro-blisters allow the implanted layer to be cleaved from the donor substrate. |
| FILED | Wednesday, November 12, 2003 |
| APPL NO | 10/706737 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/518 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057009 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Shaw H. Chen (Penfield, New York); Yanhou Geng (Rochester, New York) |
| ABSTRACT | Photonic materials include light-emitting organic oligomer compositions that include at least one light-emitting oligomer. The oligomer compositions include oligofluorenes having chiral and/or achiral pendants. The oligomer compositions also include spiro-linked oligofluorenes and fully spiro-configured terfluorenes. Methods for syntheisizing light-emitting organic oligomer compositions include preparing fluorene-based oligomers by convergent/divergent synthesis. |
| FILED | Monday, July 22, 2002 |
| APPL NO | 10/199099 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 528/370 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057571 | Courtney et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Voss Scientific, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Clifton C. Courtney (Cedar Crest, New Mexico); Donald E. Voss (Albuquerque, New Mexico) |
| ABSTRACT | An antenna concept for radiating intense, high power electromagnetic fields in the RF regime without electrical breakdown. The invention accomplishes this with high aperture and power efficiency, high gain, and in a geometry that is compact and conformal to a planar or curved surface. The antenna concept is compatible with standard rectangular waveguide feeds, or other hybrid transmission line geometries. |
| FILED | Tuesday, May 24, 2005 |
| APPL NO | 11/136675 |
| ART UNIT | 2821 — Semiconductors/Memory |
| CURRENT CPC | Communications: Radio wave antennas 343/772 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057582 | Ebersole, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Information Decision Technologies, LLC (Bedford, New Hampshire) |
| INVENTOR(S) | John Franklin Ebersole, Jr. (Bedford, New Hampshire); Mark Stanley Bastian (Manchester, New Hampshire) |
| ABSTRACT | The invention disclosed instruments a firefighter's SCBA with electronic and passive equipment, and protects this instrumentation from shock and undesirable environmental pollutant penetration. The invention provides for doing this through the use of a rugged cover on the equipment as well as soft equipment mounts. The cover provides the instrumentation with protection from impact as well as protection from contamination by environmental pollutants. |
| FILED | Tuesday, August 06, 2002 |
| APPL NO | 10/213392 |
| ART UNIT | 2673 — Semiconductors/Memory |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057594 | Russell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Stephen D. Russell (San Diego, California); Randy L. Shimabukuro (San Diego, California) |
| ABSTRACT | A reconfigurable liquid crystal display comprises a polarizer operably coupled to a beam of incident light to pass a beam of polarized light having a polarization axis. A sequence of liquid crystal display pixels serially aligned with the beam of polarized light controls the angle of the polarization axis. An analyzer passes a gray-scale portion of the beam of polarized light from the sequence of liquid crystal display pixels corresponding to the angle of the polarization axis. Each pixel in the sequence may be independently programmed, i.e. reconfigured, to vary the angle of the polarization axis for calibrating the display to a standard gray-scale and for correcting faulty pixels with VLSI on-chip driver and interface circuits. |
| FILED | Wednesday, October 01, 2003 |
| APPL NO | 10/677502 |
| ART UNIT | 2673 — Semiconductors/Memory |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/87 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057832 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Ming-Hsien Wu (Cambridge, Massachusetts); Kateri E. Paul (Mountain View, California); George M. Whitesides (Newton, Massachusetts) |
| ABSTRACT | Methods and systems for effecting responses on surfaces utilizing microlens arrays including microoptical components embedded or supported by a support element and positioned from the surface at a distance essentially equal to the image distance of the microoptical component with spacer elements are disclosed. Microlens arrays can be used to manipulate incident energy or radiation having a distribution in characteristic property(s) defining an object pattern to form a corresponding image pattern on a substrate surface. The energy can be light having a pattern or a specific wavelength, intensity or polarization or coherence alignment. The image pattern can have features of order 100 nm in size or less produced from corresponding object patterns having features in the order millimeters. The size of the object pattern can be reduced by the microlens arrays described by a factor of 100 or more using a single step process to form the image patterns. |
| FILED | Friday, March 07, 2003 |
| APPL NO | 10/384080 |
| ART UNIT | 2873 — Semiconductors/Memory |
| CURRENT CPC | Optical: Systems and elements 359/811 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057872 | Smith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | TASER International, Inc. (Scottsdale, Arizona) |
| INVENTOR(S) | Patrick W. Smith (Paradise Valley, Arizona); Magne H. Nerheim (Scottsdale, Arizona) |
| ABSTRACT | Systems and methods for immobilizing a target such as a human or animal with a stimulus signal coupled to the target via numerous electrodes select particular electrodes to use for the stimulus signal. Subsets of electrodes may be tested by applying a test signal and monitoring the energy or charge delivered during a prescribed time. If the delivered energy or charge using a particular subset of electrodes as indicated by monitoring test pulse amplitude suitably compares to a limit, then the particular subset is selected for applying the stimulus signal. A first stimulus signal may be applied to a first subset of electrodes to prompt movement of the target toward an electrode that, when better coupled to the target as a consequence of movement of the target will provide a more effective subset of electrodes for further stimulus. For example, a projectile with closely spaced electrodes may stimulate a burning sensation to attract the target to impale the target's hand on a rear facing electrode of the projectile. Use of the rear facing electrode and one or more of the closely spaced electrodes may provide a more effective stimulus circuit through tissue of the target. |
| FILED | Wednesday, December 31, 2003 |
| APPL NO | 10/750551 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Electrical systems and devices 361/232 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058092 | Moriarty |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Daniel T. Moriarty (Hudson, Massachusetts) |
| ABSTRACT | The present invention includes a design for a 20-gigabit per second two to one multiplexor, that uses: first and second input amplifiers that respectively provide output signals by respectively receiving and amplifying first and second ten-gigabit per second input signals; first and second power dividers that each produce two output data streams by respectively splitting the output signals of the first and second input amplifiers; first and second mixers that produce output signals by respectively mixing output signals of the first and second power dividers with a 10 GHz local oscillator signal; a second means for combining signals that produces an output signal by combining the output signal of the second mixer with an output data stream of the second power divider; a T/2 delay line that produces an output signal by delaying the output signal of the second combining means; and an output combiner means that outputs a 20-gigabit per second data stream by combining the output signal of the T/2 delay line with the output signal of the first combining means. |
| FILED | Thursday, January 10, 2002 |
| APPL NO | 10/041588 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Multiplex communications 370/537 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058098 | Shay |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Air Force (Washington, Delaware) |
| INVENTOR(S) | Thomas M. Shay (Albuquerque, New Mexico) |
| ABSTRACT | A coherent laser beam combining system wherein the output of a single master oscillator is split into a plurality of N signals, and the N signals are electronically modulated at unique frequencies. There is no reference signal and all of the signals are passed through phase adjusters. All N signals are optically amplified, aligned and passed through a beam splitter to split off a small sample that is imaged onto a photodetector. The photodetector output is fed to a signal processor that separates the N signals and produces N phase error signals that drive the N phase adjusters resulting in a high-powered optically coherent output signal. |
| FILED | Tuesday, November 29, 2005 |
| APPL NO | 11/289260 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/29.16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058377 | Mitsdarffer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth Bryan Mitsdarffer (Bloomington, Indiana); Lowell Roy Hoover (Bloomington, Indiana); Dean Thelen (Bloomington, Indiana) |
| ABSTRACT | A dual channel downconverter that includes a two-channel heterodyne receiver architecture for downconverting two frequency-agile, pulsed RF signals to identical fixed IF signals without the use of a tunable local oscillator. This accomplishes downconversion while preserving, in the IF output signals, any amplitude modulations present in the RF signals. The device also preserves phase difference changes present in the RF signals while rejecting the phase modulations common to those input signals. The present device facilitates complex response measurements of pulsed two-port RF devices while operating in a target system such as a radar transmitter, including insertion gain, insertion phase, residual phase noise, error vector magnitude, AM noise, and group delay, all with increased accuracy, good repeatability, good dynamic range, and decreased measurement time. |
| FILED | Thursday, August 14, 2003 |
| APPL NO | 10/641589 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Telecommunications 455/209 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058445 | Kemere et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Caleb T. Kemere (Menlo Park, California); Gopal Santhanam (Sunnyvale, California); Byron M. Yu (San Jose, California); Teresa H. Meng (Saratoga, California); Krishna V. Shenoy (Palo Alto, California) |
| ABSTRACT | A brain machine interface for decoding neural signals for control of a machine is provided. The brain machine interface estimates and then combines information from two classes of neural activity. A first estimator decodes movement plan information from neural signals representing plan activity. In one embodiment the first estimator includes an adaptive point-process filter or a maximum likelihood filter. A second estimator decodes peri-movement information from neural signals representing peri-movement activity. Each estimator is designed to estimate different aspects of movement such as movement goal variables or movement execution variables. |
| FILED | Friday, October 15, 2004 |
| APPL NO | 10/966355 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/545 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058455 | Huie, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Philip Huie, Jr. (Cupertino, California); Daniel V. Palanker (Sunnyvale, California); Harvey A. Fishman (Menlo Park, California); Alexander Vankov (Mountain View, California) |
| ABSTRACT | An interface for selective excitation or sensing of neural cells in a biological neural network is provided. The interface includes a membrane with a number of channels passing through the membrane. Each channel has at least one electrode within it. Neural cells in the biological neural network grow or migrate into the channels, thereby coming into close proximity to the electrodes. Once one or more neural cells have grown or migrated into a channel, a voltage applied to the electrode within the channel selectively excites the neural cell (or cells) in that channel. The excitation of these neural cell(s) will then transmit throughout the neural network (i.e. cells and axons) that is associated with the neural cell(s) stimulated in the channel. |
| FILED | Friday, December 19, 2003 |
| APPL NO | 10/742584 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/116 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058544 | Uzarski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Donald R. Uzarski (Champaign, Illinois); Michael N. Grussing (Champaign, Illinois) |
| ABSTRACT | A knowledge-based condition survey inspection (KBSCI) framework and procedure for use with an engineering management system (EMS) that tailors types of condition survey inspections (CSIs) and inspection intervals to empirically-established life cycles of component-sections. Embodiments of the invention facilitate proactive life cycle management, scheduling appropriate types of CSIs only when needed. The frequency and type of inspection is tailored to items important to a facility manager, such as the importance to the operation of individual component-sections and their individual life cycle, not the overall life cycle of a system or facility. Further, additional useful information is available from the data collected to maintain embodiments of the KBCSI framework so that meaningful “What-If” analysis may be performed in support of decision makers. By tailoring CSIs to needs rather than an arbitrary inspection schedule designed to only catch deficiencies, significant life cycle cost savings are realized. |
| FILED | Friday, July 09, 2004 |
| APPL NO | 10/886609 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/184 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058555 | Schwartz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David F. Schwartz (San Diego, California); J. William Helton (Del Mar, California); Jeffery C. Allen (San Diego, California) |
| ABSTRACT | A predictor for optimal transducer power gain computes the maximum transducer power gain attainable by a lossless matching network for a given load operating over selected non-overlapping (disjoint) sub-bands within a frequency band of operation. |
| FILED | Wednesday, May 29, 2002 |
| APPL NO | 10/157413 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058556 | Desai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Goodrich Pump and Engine Control Systems, Inc. (West Hartford, Connecticut); Pratt and Whitney Canada Corp. (Longueuil, Canada) |
| INVENTOR(S) | Mihir C. Desai (Yorba Linda, California); Cristina Crainic (Longueuil, Canada) |
| ABSTRACT | An adaptive aero-thermodynamic engine model is disclosed which incorporates a plurality of model engine operating parameters, a plurality of nominal component efficiencies and corresponding efficiency modifier functions. The engine model is adapted by measuring a plurality of engine operating parameters corresponding to the plurality of model engine operating parameters during steady state operation of the engine over a plurality of data points, matching each of the model engine operating parameters to respective measured engine operating parameters by iteratively adapting each of the nominal component efficiencies using the corresponding efficiency modifier functions, estimating actual component efficiencies based upon the adapted nominal component efficiencies, and inputting the estimated actual component efficiencies into the engine model. |
| FILED | Wednesday, September 26, 2001 |
| APPL NO | 09/963221 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/8 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058558 | Reichenthal |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Boeing Company (Seattle, Washington) |
| INVENTOR(S) | Steven W. Reichenthal (Yorba Linda, California) |
| ABSTRACT | A simulation system and method enabled through the use of an XML-based Simulation Reference Markup Language (SRML) and a corresponding system runtime environment. The simulation system comprises a simulation reference simulator adapted to receive an SRML simulation model including a simulation item. The simulation reference simulator comprises an item manager for loading properties of each item of the simulation model, and an event manager for processing the simulation model. A method of conducting simulations comprises the steps of defining a simulation model with Simulation Reference Markup Language, communicating the model to a simulation reference simulator, executing the model with the simulation reference simulator, and providing an output of the modeled events. |
| FILED | Friday, May 25, 2001 |
| APPL NO | 09/865293 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/17 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058910 | Bharadwaj et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ramesh Bharadwaj (Alexandria, Virginia); Steve Sims (Arlington, Virginia) |
| ABSTRACT | An invariant checking method and apparatus using binary decision diagrams (BDDs) in combination with constraint solvers for determining whether a system property is an invariant of a system description. The invariant checking method receives system descriptions and system properties and transforms them into a model formula. Specific variables are eliminated from the model formula and a corresponding output formula is generated. The output formula is transformed into a logic formula by substituting a new logic variable for each integer constraint in the output formula. A constrained BDD is constructed from the logic formula. The constrained BDD uses a heuristic algorithm to order the logic variables in the paths leading to true or false. A constraint solver is applied to the integer constraints that correspond to the occurrences of logic variables in the BDD paths, which determines whether the system property is or is not an invariant of the system description. |
| FILED | Thursday, June 27, 2002 |
| APPL NO | 10/180043 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Computer-aided design and analysis of circuits and semiconductor masks 716/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
H0002157 — Method of producing corrosion resistant metal alloys with improved strength and ductility
| US H2157 | Aprigliano et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Louis F. Aprigliano (Berlin, Maryland); Leslie K. Kohler (Boyds, Maryland) |
| ABSTRACT | Nickel and chromium as the exclusive components of an alloy is formed by mixing under cover of nitrogen gas and spray casting thereof wherein a molten outflow stream of such alloy components is atomized by exposure to jets of the nitrogen gas after pressurization, resulting in formation of molten alloy metal droplets deposited on to a surface. |
| FILED | Thursday, September 07, 2000 |
| APPL NO | 09/656017 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Metal founding 164/46 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07055469 | Lawrence et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Caterpillar Inc (Peoria, Illinois) |
| INVENTOR(S) | Keith E. Lawrence (Peoria, Illinois); Bryan E. Strawbridge (Dunlap, Illinois); Charles H. Dutart (Washington, Illinois) |
| ABSTRACT | An apparatus and method for varying a compression ratio of an engine having a block and a head mounted thereto. The apparatus and method includes a cylinder having a block portion and a head portion, a piston linearly movable in the block portion of the cylinder, a cylinder plug linearly movable in the head portion of the cylinder, and a valve located in the cylinder plug and operable to provide controlled fluid communication with the block portion of the cylinder. |
| FILED | Tuesday, February 18, 2003 |
| APPL NO | 10/369050 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion engines 123/48.AA0 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07055486 | Hoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Caterpillar Inc. (Peoria, Illinois) |
| INVENTOR(S) | Brian D. Hoff (East Peoria, Illinois); Kris William Johnson (Washington, Illinois); Marcelo C. Algrain (Peoria, Illinois); Sivaprasad Akasam (Peoria, Illinois) |
| ABSTRACT | A method of controlling the delivery of fluid to an engine includes receiving a fuel flow rate signal. An electric pump is arranged to deliver fluid to the engine. The speed of the electric pump is controlled based on the fuel flow rate signal. |
| FILED | Tuesday, December 23, 2003 |
| APPL NO | 10/742885 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion engines 123/196.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07055750 | Carrender |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute K1-53 (Richland, Washington) |
| INVENTOR(S) | Curtis Lee Carrender (Morgan Hill, California) |
| ABSTRACT | A system and related device for converting encoded data from one format into one or more formats, including barcode and radio frequency identification tag formats, the system including a programmer configured to read a barcode and using the barcode data encoded thereon automatically write the data to a radio frequency (RF) tag and to read the contents of a RF tag and automatically generate a barcode with the information contained in the tag or information related thereto, preferably without decoding the encoded data. |
| FILED | Friday, May 07, 2004 |
| APPL NO | 10/841943 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Registers 235/472.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056063 | Richardson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | John G. Richardson (Idaho Falls, Idaho); Reva A. Nickelson (Shelley, Idaho); Paul A. Sloan (Rigby, Idaho); Kevin M. Kostelnik (Idaho Falls, Idaho) |
| ABSTRACT | A containment system for use adjacent to a selected region of a subterranean formation and comprising a plurality of laterally interlocked casing strings. At least one electrically conductive element is disposed along at least a portion of a casing string and is used for performing electrical time domain reflectometry. At least one protective element may be positioned between portions of adjacent casing strings of the barrier, and at least one electrically conductive element may be disposed at least partially within the at least one protective element for use in indicating at least one characteristic of at least a portion of the containment system. Electrical time domain reflectometry (TDR) may be used to indicate the at least one characteristic; for instance, TDR may be used to indicate leakage through the barrier or a discontinuity or void in a barrier filler material. |
| FILED | Thursday, May 20, 2004 |
| APPL NO | 10/850636 |
| ART UNIT | 3673 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Hydraulic and earth engineering 45/129.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056487 | Newby |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Siemens Power Generation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Richard Allen Newby (Pittsburgh, Pennsylvania) |
| ABSTRACT | A gas cleaning system for removing at least a portion of contaminants, such as halides, sulfur, particulates, mercury, and others, from a synthesis gas (syngas). The gas cleaning system may include one or more filter vessels coupled in series for removing halides, particulates, and sulfur from the syngas. The gas cleaning system may be operated by receiving gas at a first temperature and pressure and dropping the temperature of the syngas as the gas flows through the system. The gas cleaning system may be used for an application requiring clean syngas, such as, but not limited to, fuel cell power generation, IGCC power generation, and chemical synthesis. |
| FILED | Friday, June 06, 2003 |
| APPL NO | 10/456037 |
| ART UNIT | 1754 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry of inorganic compounds 423/650 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056611 | Fabis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Siemens Power Generation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Thomas R. Fabis (Delmont, Pennsylvania); Joseph M. Makiel (Monroeville, Pennsylvania); Stephen E. Veyo (Murrysville, Pennsylvania) |
| ABSTRACT | A method and system are provided for improved control of the operating temperature of a fuel cell (32) utilizing an improved temperature control system (30) that varies the flow rate of inlet air entering the fuel cell (32) in response to changes in the operating temperature of the fuel cell (32). Consistent with the invention an improved temperature control system (30) is provided that includes a controller (37) that receives an indication of the temperature of the inlet air from a temperature sensor (39) and varies the heat output by at least one heat source (34, 36) to maintain the temperature of the inlet air at a set-point Tinset. The controller (37) also receives an indication of the operating temperature of the fuel cell (32) and varies the flow output by an adjustable air mover (33), within a predetermined range around a set-point Fset, in order to maintain the operating temperature of the fuel cell (32) at a set-point Topset. |
| FILED | Tuesday, July 16, 2002 |
| APPL NO | 10/196319 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/24 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056661 | Korlach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jonas Korlach (Ithaca, New York); Watt W. Webb (Ithaca, New York); Michael Levene (Ithaca, New York); Stephen Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Mathieu Foquet (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined. |
| FILED | Wednesday, May 17, 2000 |
| APPL NO | 09/572530 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056676 | Korlach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jonas Korlach (Ithaca, New York); Watt W. Webb (Ithaca, New York); Michael Levene (Ithaca, New York); Stephen Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Mathieu Foquet (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined. |
| FILED | Thursday, December 16, 2004 |
| APPL NO | 11/015138 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056721 | Dunn-Coleman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Genencor International, Inc. (Palo Alto, California) |
| INVENTOR(S) | Nigel Dunn-Coleman (Los Gatos, California); Frits Goedegebuur (Vlaardingen, Netherlands); Michael Ward (San Francisco, California); Jian Yao (Sunnyvale, California) |
| ABSTRACT | The present invention provides a novel endoglucanase nucleic acid sequence, designated egl6, and the corresponding EGVI amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVI, recombinant EGVI proteins and methods for producing the same. |
| FILED | Tuesday, December 18, 2001 |
| APPL NO | 10/026994 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/209 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056724 | Wong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Pak C. Wong (Richland, Washington); Kwong K. Wong (Sugar Land, Texas); Harlan P. Foote (Richland, Washington) |
| ABSTRACT | Current technologies allow the generation of artificial DNA molecules and/or the ability to alter the DNA sequences of existing DNA molecules. With a careful coding scheme and arrangement, it is possible to encode important information as an artificial DNA strand and store it in a living host safely and permanently. This inventive technology can be used to identify origins and protect R&D investments. It can also be used in environmental research to track generations of organisms and observe the ecological impact of pollutants. Today, there are microorganisms that can survive under extreme conditions. As well, it is advantageous to consider multicellular organisms as hosts for stored information. These living organisms can provide as memory housing and protection for stored data or information. The present invention provides well for data storage in a living organism wherein at least one DNA sequence is encoded to represent data and incorporated into a living organism. |
| FILED | Friday, May 24, 2002 |
| APPL NO | 10/155761 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056815 | Weng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Xiaojun Weng (Ann Arbor, Michigan); Rachel S. Goldman (Ann Arbor, Michigan) |
| ABSTRACT | A method for forming a semi-conductor material is provided that comprises forming a donor substrate constructed of GaAs, providing a receiver substrate, implanting nitrogen into the donor substrate to form an implanted layer comprising GaAs and nitrogen. The implanted layer is bonded to the receiver substrate and annealed to form GaAsN and nitrogen micro-blisters in the implanted layer. The micro-blisters allow the implanted layer to be cleaved from the donor substrate. |
| FILED | Wednesday, November 12, 2003 |
| APPL NO | 10/706737 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/518 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056901 | Frechet et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jean M. J. Frechet (Oakland, California); Niren Murthy (Berkeley, California) |
| ABSTRACT | Novel microgels, microparticles and related polymeric materials capable of delivering bioactive materials to cells for use as vaccines or therapeutic agents. The materials are made using a crosslinker molecule that contains a linkage cleavable under mild acidic conditions. The crosslinker molecule is exemplified by a bisacryloyl acetal crosslinker. The new materials have the common characteristic of being able to degrade by acid hydrolysis under conditions commonly found within the endosomal or lysosomal compartments of cells thereby releasing their payload within the cell. The materials can also be used for the delivery of therapeutics to the acidic regions of tumors and sites of inflammation. |
| FILED | Friday, March 28, 2003 |
| APPL NO | 10/401496 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/54 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057055 | Bergman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Robert C. Bergman (Kensington, California); Steven R. Klei (Berkeley, California) |
| ABSTRACT | A process for labeling organic compounds with deuterium and tritium is described using specific catalysts. |
| FILED | Tuesday, October 04, 2005 |
| APPL NO | 11/243852 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 549/429 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057072 | Mitchell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alexander R. Mitchell (Livermore, California); Michael D. Coburn (Santa Fe, New Mexico); Gregory S. Lee (San Ramon, California); Robert D. Schmidt (Livermore, California); Philip F. Pagoria (Livermore, California); Peter C. Hsu (Pleasanton, California) |
| ABSTRACT | A method to convert surplus nitroarene explosives (picric acid, ammonium picrate,) into TATB is described. The process comprises three major steps: conversion of picric acid/ammonium picrate into picramide; conversion of picramide to TATB through vicarious nucleophilic substitution (VNS) of hydrogen chemistry; and purification of TATB. |
| FILED | Monday, August 02, 2004 |
| APPL NO | 10/910659 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057073 | Mitchell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alexander R. Mitchell (Livermore, California); Michael D. Coburn (Santa Fe, New Mexico); Gregory S. Lee (San Ramon, California); Robert D. Schmidt (Livermore, California); Philip F. Pagoria (Livermore, California); Peter C. Hsu (Pleasanton, California) |
| ABSTRACT | A method to convert surplus nitroarene explosives into trinitrophloroglucinol and triaminotrinitrobenzene (TATB) is described. Picric acid is directly aminated to diaminopicric acid, which is converted to trinitrophloroglucinol and triaminotrinitrobenzene. |
| FILED | Wednesday, August 04, 2004 |
| APPL NO | 10/912723 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057256 | Carey, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | James Edward Carey, III (Brighton, Massachusetts); Eric Mazur (Concord, Massachusetts) |
| ABSTRACT | In one aspect, the present invention provides a silicon photodetector having a surface layer that is doped with sulfur inclusions with an average concentration in a range of about 0.5 atom percent to about 1.5 atom percent. The surface layer forms a diode junction with an underlying portion of the substrate. A plurality of electrical contacts allow application of a reverse bias voltage to the junction in order to facilitate generation of an electrical signal, e.g., a photocurrent, in response to irradiation of the surface layer. The photodetector exhibits a responsivity greater than about 1 A/W for incident wavelengths in a range of about 250 nm to about 1050 nm, and a responsivity greater than about 0.1 A/W for longer wavelengths, e.g., up to about 3.5 microns. |
| FILED | Friday, September 24, 2004 |
| APPL NO | 10/950230 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/463 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057390 | Sinkine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Southeastern Univ. Research Assn. (Newport News, Virginia) |
| INVENTOR(S) | Nikolai I. Sinkine (Newport News, Virginia); Chen Yan (Yorktown, Virginia); Cornelis Apeldoorn (Gloucester, Virginia); Jeffrey Glenn Dail (Poquoson, Virginia); Randolph Frank Wojcik (Yorktown, Virginia); William Gunning (Newport News, Virginia) |
| ABSTRACT | An improved raster magnet driver for a linear particle beam is based on an H-bridge technique. Four branches of power HEXFETs form a two-by-two switch. Switching the HEXFETs in a predetermined order and at the right frequency produces a triangular current waveform. An H-bridge controller controls switching sequence and timing. The magnetic field of the coil follows the shape of the waveform and thus steers the beam using a triangular rather than a sinusoidal waveform. The system produces a raster pattern having a highly uniform raster density distribution, eliminates target heating from non-uniform raster density distributions, and produces higher levels of beam current. |
| FILED | Monday, September 20, 2004 |
| APPL NO | 10/945408 |
| ART UNIT | 2821 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/318 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058153 | Akers |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Douglas W. Akers (Idaho Falls, Idaho) |
| ABSTRACT | A non-destructive testing method comprises providing a specimen having at least one positron emitter therein; determining a threshold energy for activating the positron emitter; and determining whether a half-life of the positron emitter is less than a selected half-life. If the half-life of the positron emitter is greater than or equal to the selected half-life, then activating the positron emitter by bombarding the specimen with photons having energies greater than the threshold energy and detecting gamma rays produced by annihilation of positrons in the specimen. If the half-life of the positron emitter is less then the selected half-life, then alternately activating the positron emitter by bombarding the specimen with photons having energies greater then the threshold energy and detecting gamma rays produced by positron annihilation within the specimen. |
| FILED | Thursday, October 10, 2002 |
| APPL NO | 10/269807 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Induced nuclear reactions: Processes, systems, and elements 376/157 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058243 | Tao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Mississippi State University (Mississippi State, Mississippi) |
| INVENTOR(S) | Shiquan Tao (Starkville, Mississippi); Rajeev Jindal (Starkville, Mississippi); Christopher Winstead (Starkville, Mississippi); Jagdish P. Singh (Starkville, Mississippi) |
| ABSTRACT | A simple, economic wet chemical procedure is described for making sol-gel fibers. The sol-gel fibers made from this process are transparent to ultraviolet, visible and near infrared light. Light can be guided in these fibers by using an organic polymer as a fiber cladding. Alternatively, air can be used as a low refractive index medium. The sol-gel fibers have a micro pore structure which allows molecules to diffuse into the fiber core from the surrounding environment. Chemical and biochemical reagents can be doped into the fiber core. The sol-gel fiber can be used as a transducer for constructing an optical fiber sensor. The optical fiber sensor having an active sol-gel fiber core is more sensitive than conventional evanescent wave absorption based optical fiber sensors. |
| FILED | Thursday, January 17, 2002 |
| APPL NO | 10/046731 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058866 | Flanagan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | John D. Flanagan (Rhinebeck, New York); Jay R. Herring (Poughkeepsie, New York); Tin-Chee Lo (Fishkill, New York) |
| ABSTRACT | A method for performing AC self-test on an integrated circuit, including a system clock for use during normal operation. The method includes applying a long data capture pulse to a first test register in response to the system clock, and further applying at an speed data launch pulse to the first test register in response to the system clock. Inputting the data from the first register to a logic path in response to applying the at speed data launch pulse to the first test register. Applying at speed data capture pulse to a second test register in response to the system clock. Inputting the output from the logic path to the second test register in response to applying the at speed data capture pulse to the second register. Applying a long data launch pulse to the second test register in response to the system clock. |
| FILED | Wednesday, April 24, 2002 |
| APPL NO | 10/131554 |
| ART UNIT | 2138 — Memory Access and Control |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/726 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07056532 | Kabanov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Univ. Nebraska Bd. of Regents (Lincoln, Nebraska); Moscow State Univ. (Moscow, Russian Federation); McGill Univ. (Montreal, Canada) |
| INVENTOR(S) | Alexander V. Kabanov (Omaha, Nebraska); Adi Eisenberg (Montreal, Canada); Victor A. Kabanov (Moscow, Russian Federation) |
| ABSTRACT | A composition for facilitating delivery of biological agents, comprising a supramolecular complex including as constituents a block copolymer, having at least one nonionic, water soluble segment and at least one polyionic segment, and at least one charged surfactant having hydrophobic groups, the charge of the surfactant being opposite to that of the polyionic segment of the block copolymer. The constituents of the complex are bound by interaction between the opposite charges thereof and between surfactant hydrophobic groups. The complex may include an anionic surfactant having a biological activity, in which case the net charge of such anionic surfactant is no more than about 10. |
| FILED | Thursday, June 11, 1998 |
| APPL NO | 09/445656 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/486 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056661 | Korlach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jonas Korlach (Ithaca, New York); Watt W. Webb (Ithaca, New York); Michael Levene (Ithaca, New York); Stephen Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Mathieu Foquet (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined. |
| FILED | Wednesday, May 17, 2000 |
| APPL NO | 09/572530 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056676 | Korlach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Jonas Korlach (Ithaca, New York); Watt W. Webb (Ithaca, New York); Michael Levene (Ithaca, New York); Stephen Turner (Ithaca, New York); Harold G. Craighead (Ithaca, New York); Mathieu Foquet (Ithaca, New York) |
| ABSTRACT | The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the polymerization reaction is measured on a molecule of nucleic acid, i.e. the activity of a nucleic acid polymerizing enzyme on the template nucleic acid molecule to be sequenced is followed in real time. The sequence is deduced by identifying which base is being incorporated into the growing complementary strand of the target nucleic acid by the catalytic activity of the nucleic acid polymerizing enzyme at each step in the sequence of base additions. A polymerase on the target nucleic acid molecule complex is provided in a position suitable to move along the target nucleic acid molecule and extend the oligonucleotide primer at an active site. A plurality of labelled types of nucleotide analogs are provided proximate to the active site, with each distinguishable type of nucleotide analog being complementary to a different nucleotide in the target nucleic acid sequence. The growing nucleic acid strand is extended by using the polymerase to add a nucleotide analog to the nucleic acid strand at the active site, where the nucleotide analog being added is complementary to the nucleotide of the target nucleic acid at the active site. The nucleotide analog added to the oligonucleotide primer as a result of the polymerizing step is identified. The steps of providing labelled nucleotide analogs, polymerizing the growing nucleic acid strand, and identifying the added nucleotide analog are repeated so that the nucleic acid strand is further extended and the sequence of the target nucleic acid is determined. |
| FILED | Thursday, December 16, 2004 |
| APPL NO | 11/015138 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056866 | Chu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Houston-University Park (Houston, Texas) |
| INVENTOR(S) | Ching-Wu Chu (Houston, Texas) |
| ABSTRACT | Described is a superconducting composition comprising an oxide complex of the formula [L1−xMx]aAbOy wherein L is lanthanum, lutetium, yttrium, or scandium; A is copper, bismuth, titanium, tungsten, zirconium, tantalum, niobium, or vanadium; M is barium, strontium, calcium, magnesium or mercury; and “a” is 1 to 2; “b” is 1; and “x” is a number in the range of 0.01 to 1.0; and “y” is about 2 to about 4. The oxide complexes of the invention are prepared by a solid-state reaction procedure which produces an oxide complex having an enhanced superconducting transition temperature compared to an oxide complex of like empirical composition prepared by a coprecipitation—high temperature decomposition procedure. With an oxide complex prepared by the solid-state reaction of the invention a transition temperature as high as 100°K has been observed even under atmospheric pressure. |
| FILED | Thursday, March 26, 1987 |
| APPL NO | 07/032041 |
| ART UNIT | 1751 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Superconductor technology: Apparatus, material, process 55/125 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057009 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Shaw H. Chen (Penfield, New York); Yanhou Geng (Rochester, New York) |
| ABSTRACT | Photonic materials include light-emitting organic oligomer compositions that include at least one light-emitting oligomer. The oligomer compositions include oligofluorenes having chiral and/or achiral pendants. The oligomer compositions also include spiro-linked oligofluorenes and fully spiro-configured terfluorenes. Methods for syntheisizing light-emitting organic oligomer compositions include preparing fluorene-based oligomers by convergent/divergent synthesis. |
| FILED | Monday, July 22, 2002 |
| APPL NO | 10/199099 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 528/370 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058242 | Lidorikis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Elefterios Lidorikis (Athens, Greece); Steven G. Johnson (Cambridge, Massachusetts); Michelle L. Povinelli (Somerville, Massachusetts); John D. Joannopoulos (Belmont, Massachusetts) |
| ABSTRACT | A photonic crystal includes a plurality of photonic crystal slabs that is suited for confining TE polarizations and TM polarizations. The photonic crystal slabs include alternating slabs of dielectric rods and air holes. The alternating slabs create a lateral symmetry plane. The alternating slabs of dielectric rods and air holes further include planar line defects resulting in the formation of defect bands inside the bandgap of the photonic crystal. |
| FILED | Thursday, May 20, 2004 |
| APPL NO | 10/849593 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058445 | Kemere et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Caleb T. Kemere (Menlo Park, California); Gopal Santhanam (Sunnyvale, California); Byron M. Yu (San Jose, California); Teresa H. Meng (Saratoga, California); Krishna V. Shenoy (Palo Alto, California) |
| ABSTRACT | A brain machine interface for decoding neural signals for control of a machine is provided. The brain machine interface estimates and then combines information from two classes of neural activity. A first estimator decodes movement plan information from neural signals representing plan activity. In one embodiment the first estimator includes an adaptive point-process filter or a maximum likelihood filter. A second estimator decodes peri-movement information from neural signals representing peri-movement activity. Each estimator is designed to estimate different aspects of movement such as movement goal variables or movement execution variables. |
| FILED | Friday, October 15, 2004 |
| APPL NO | 10/966355 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/545 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058628 | Page |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Lawrence Page (Stanford, California) |
| ABSTRACT | A method assigns importance ranks to nodes in a linked database, such as any database of documents containing citations, the world wide web or any other hypermedia database. The rank assigned to a document is calculated from the ranks of documents citing it. In addition, the rank of a document is calculated from a constant representing the probability that a browser through the database will randomly jump to the document. The method is particularly useful in enhancing the performance of search engine results for hypermedia databases, such as the world wide web, whose documents have a large variation in quality. |
| FILED | Monday, July 02, 2001 |
| APPL NO | 09/895174 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07055625 | Myrick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Honeybee Robotics, Ltd. (New York, New York) |
| INVENTOR(S) | Thomas M. Myrick (Warren, New Jersey); Stephen Gorevan (New York, New York) |
| ABSTRACT | An autonomous subsurface drilling device has spaced-apart forward and rearward “feet” sections coupled to an axial thruster mechanism between them to operate using an inchworm method of mobility. In one embodiment, forward and rearward drill sections are carried on forward and rearward “feet” sections for drilling into material in the borehole in both forward and rearward directions, to allow the device to maneuver in any direction underground. In another embodiment, a front drill section has a drill head for cutting into the borehole and conveying cuttings through a center spine tube to an on-board depository for the cuttings. The feet sections of the device employ a foot scroll drive unit to provide radial thrust and synchronous motion to the feet for gripping the borehole wall. The axial thrust mechanism has a tandem set of thrusters in which the second thruster is used to provide the thrust needed for drilling, but not walking. A steering mechanism composed of concentric inner and outer eccentric rings provided with the rearward feet section allow small corrections in both direction and magnitude to the drilling direction as drilling commences. |
| FILED | Tuesday, January 27, 2004 |
| APPL NO | 10/766414 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Boring or penetrating the earth 175/26 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056428 | Narayanan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasedena, California) |
| INVENTOR(S) | Sekharipuram R. Narayanan (Altadena, California); William Chun (Los Angeles, California); Barbara Jeffries-Nakamura (San Marino, California); Thomas I. Valdez (Covina, California) |
| ABSTRACT | A device for electrolysis of an aqueous solution of an organic fuel. The electrolyte is a solid-state polymer membrane with anode and cathode catalysts on both surfaces for electro-oxidization and electro-reduction. A low-cost and portable hydrogen generator can be made based on the device with organic fuels such as methanol. |
| FILED | Tuesday, March 18, 2003 |
| APPL NO | 10/391855 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Electrolysis: Processes, compositions used therein, and methods of preparing the compositions 25/637 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07056866 | Chu |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | University of Houston-University Park (Houston, Texas) |
| INVENTOR(S) | Ching-Wu Chu (Houston, Texas) |
| ABSTRACT | Described is a superconducting composition comprising an oxide complex of the formula [L1−xMx]aAbOy wherein L is lanthanum, lutetium, yttrium, or scandium; A is copper, bismuth, titanium, tungsten, zirconium, tantalum, niobium, or vanadium; M is barium, strontium, calcium, magnesium or mercury; and “a” is 1 to 2; “b” is 1; and “x” is a number in the range of 0.01 to 1.0; and “y” is about 2 to about 4. The oxide complexes of the invention are prepared by a solid-state reaction procedure which produces an oxide complex having an enhanced superconducting transition temperature compared to an oxide complex of like empirical composition prepared by a coprecipitation—high temperature decomposition procedure. With an oxide complex prepared by the solid-state reaction of the invention a transition temperature as high as 100°K has been observed even under atmospheric pressure. |
| FILED | Thursday, March 26, 1987 |
| APPL NO | 07/032041 |
| ART UNIT | 1751 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Superconductor technology: Apparatus, material, process 55/125 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058316 | Vilnrotter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Victor Vilnrotter (Pasadena, California); Meera Srinivasan (Pasadena, California) |
| ABSTRACT | An optical communications receiver comprising a wide-band optical detector array and a high-speed digital signal processor programmed to operate on the raw data from the detector array to ameliorate the effects of atmospheric turbulence on the performance of the optical receiver in real-time while operating within the terrestrial atmosphere, or while attempting to communicate through any similar turbulent medium is provided. A method of sending optical communications through such optical communications receivers is also provided. |
| FILED | Wednesday, November 28, 2001 |
| APPL NO | 09/996233 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Optical communications 398/202 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07058737 | Ellerbrock et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Boeing Company (Seattle, Washington) |
| INVENTOR(S) | Philip J. Ellerbrock (Bridgeton, Missouri); Robert L. Grant (St. Peters, Missouri); Daniel W. Konz (Hazelwood, Missouri); Joseph P. Winkelmann (St. Peters, Missouri) |
| ABSTRACT | The present invention provides a network device interface and method for digitally connecting a plurality of data channels, such as sensors, actuators, and subsystems, to a controller using a network bus. The network device interface interprets commands and data received from the controller and polls the data channels in accordance with these commands. Specifically, the network device interface receives digital commands and data from the controller, and based on these commands and data, communicates with the data channels to either retrieve data in the case of a sensor or send data to activate an actuator. Data retrieved from the sensor is then converted into digital signals and transmitted back to the controller. In one embodiment, the bus controller sends commands and data a defined bit rate, and the network device interface senses this bit rate and sends data back to the bus controller using the defined bit rate. |
| FILED | Thursday, December 04, 2003 |
| APPL NO | 10/728349 |
| ART UNIT | 2111 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electrical computers and digital data processing systems: Input/output 710/61 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07056864 | Rosskopf et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Erin Nichole Rosskopf (Fort Pierce, Florida); William H. Basinger (Hiram, Georgia); Husein Ahmad-Mousa Ajwa (Salinas, California) |
| ABSTRACT | A method for reducing pests in an object or area by applying to the object or area a pest reducing effective amount of halogen substituted ethanol (e.g., 2-iodoethanol, 2-bromoethanol, or mixtures thereof). The pests may be, for example, fungi, insects, nematodes, bacteria, weeds, or mixtures thereof. The object or area may be, for example, soil, structures, agricultural commodities, plants, or mixtures thereof. |
| FILED | Tuesday, June 17, 2003 |
| APPL NO | 10/462912 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Plant protecting and regulating compositions 54/356 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057087 | Podila et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Control of Michigan Technological University (Houghton, Wisconsin) |
| INVENTOR(S) | Gopi Krishna Podila (Houghton, Michigan); Leland James Cseke (Madison, Alabama); Banalata Sen (Durham, North Carolina); David F. Karnosky (Chassell, Michigan) |
| ABSTRACT | The present invention provides compositions and methods for producing a transgenic plant that exhibits altered characteristics resulting from over expression or under expression of a novel polypeptide PtM3 or its homolog PtM4. The altered characteristics resulting from over-expression include at least one of the ability to convert axillary meristem to floral meristem; to accelerate flowering i.e., early flowering; to increase fruit production; to increase nut production; to increase seed output; to increase branching; to increase flower production; to increase fruit yield; to increase flower yield and a combination thereof. The altered characteristics resulting from suppressed expression include at least one of complete sterility; partial sterility (sterility of only one sex of a bisexual plant); reduced pollen production; decreased flowering; increased biomass and combinations thereof. Furthermore, once the transgenic plant is sterile, additional exogenous sequences may be incorporated into the sterile plant genome, resulting in other desired plant characteristics. Related promoter, gene constructs, methods, antibodies and kits are also provided. |
| FILED | Friday, July 26, 2002 |
| APPL NO | 10/206653 |
| ART UNIT | 1638 — Organic Chemistry |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/278 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07057205 | Bao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Lucent Technologies Inc. (Murray Hill, New Jersey) |
| INVENTOR(S) | Zhenan Bao (Stanford, California); Evert-Jan Borkent (Groningen, Netherlands) |
| ABSTRACT | The present invention provides an organic field-effect transistor (OFET) and a method of fabricating the OFET. The OFET, configured to function as a p-type semiconductor, includes a substrate having a top surface and a semiconductor layer located over the top surface. The semiconductor layer comprises organic semiconductor molecules. Each of the organic semiconductor molecules includes a core having conjugated pi bonds, a fluorinated alkyl group, and an alkyl spacer group having a chain of two or more carbon atoms. One end of the chain is bonded to the fluorinated alkyl group and another end of the chain is bonded to the core. Substituents coupled to the carbon atoms have an electronegativity of less than about 4. |
| FILED | Wednesday, March 17, 2004 |
| APPL NO | 10/802973 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 07057134 | Denney et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Loma Linda University Medical Center (Loma Linda, California) |
| INVENTOR(S) | Paul E. Denney (Columbus, Ohio); Jay R. Eastman (Westerville, Ohio); Paul M. Fallara (Columbus, Ohio); Andrew P. Joseph (Pickerington, Ohio); John S. Phillips (Powell, Ohio); Michael N. Patena (Pataskala, Ohio); Tim Burnham (Reynoldsburg, Ohio); Paul Coleman (Westerville, Ohio) |
| ABSTRACT | A laser manipulation system controllably moves a laser head relative to a surface of an inhabitable structure for irradiating the surface with laser light from the laser head. The laser manipulation system includes a positioning mechanism coupled to the laser head. The positioning mechanism includes a first-axis position system adapted to move the laser head along a first direction substantially parallel to the surface. The positioning mechanism further includes a second-axis position system coupled to the first-axis position system and adapted to move the laser head along a second direction substantially parallel to the surface. The laser manipulation system further includes an anchoring mechanism coupled to the positioning mechanism and releasably coupled to the structure. |
| FILED | Wednesday, October 22, 2003 |
| APPL NO | 10/691481 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electric heating 219/121.780 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07056061 | Kukor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Jerome J. Kukor (East Windsor, New Jersey); Kyoungphile Nam (Seoul, South Korea) |
| ABSTRACT | A method of treatment of a contaminated material contaminated with an organic compound. The method includes treating the contaminate with a bioremediation step followed by a chemical oxidation step. The bioremediation step includes contacting the contaminate with a microbial consortium under conditions suitable for the consortium to mediate solubilization or biodegradation of the organic compound or chemical oxidation products thereof. The subsequent chemical oxidation step includes treating the bioremediated contaminate with: a transition metal in soluble form; a chelator of the transition metal, to form a transition metal:chelator complex; an oxidizing agent that provides a reactive free radical in the presence of the transition metal complex; and a buffering compound to maintain the pH in a neutral range. The reactive free radical initiates a chemical reaction with the organic compound to produce reaction products of the organic compound. |
| FILED | Wednesday, March 24, 2004 |
| APPL NO | 10/807834 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Hydraulic and earth engineering 45/128.750 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057015 | Gage et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Fred H. Gage (La Jolla, California); Steven T. Suhr (La Jolla, California); Elad B. Gil (Boston, Massachusetts); Marie-Claude C. Senut (La Jolla, California) |
| ABSTRACT | The invention provides chimeric proteins having at least two functional protein units, each containing the dimerization domain of a member of the steroid/thyroid hormone nuclear receptor superfamily. The chimeric proteins can fold under crystallization conditions to form functional entities. The functional entities optionally contain a novel flexible peptide linker of variable lengths between at least two of the protein units. In a preferred embodiment, the linker is designed to be increased in increments of 12 amino acids each to aid in preparation of variant chimeric proteins. The DNA binding characteristics of the invention functional entities differ from those of wild-type complexes formed between “monomeric” receptors and their binding partners. Some functional entities, e.g. dimers expressed as fusion proteins, transactivate responsive promoters in a manner similar to wild-type complexes, while others do not promote transactivation and function instead essentially as constitutive repressors. The invention further provides nucleotide sequences encoding the invention chimeric proteins, cells containing such nucleotide sequences, and methods for using the invention chimeric proteins to modulate expression of one or more exogenous genes in a subject organism. In addition, isolated protein crystals suitable for x-ray diffraction analysis and methods for obtaining putative ligands for the invention chimeric proteins are provided. |
| FILED | Wednesday, October 20, 1999 |
| APPL NO | 09/421971 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07057538 | D'Amore |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Northrop Grumman Corporation (Los Angeles, California) |
| INVENTOR(S) | Matthew M. D'Amore (Los Angeles, California) |
| ABSTRACT | An encoder circuit and a related method for its operation, in which digital encoding, such as differential phase-shift keyed (DPSK) encoding, is performed as a parallel operation on N bits at a time. Each encoded bit is both output in parallel with the others of the N bits and is coupled as an input to encode the immediately next bit in the input data stream. The Nth encoded bit is fed back to the first encoder stage for use in encoding the (N+1)th bit in the input stream. The encoder typically includes a serial-to-parallel converter at the encoder inputs, and a parallel-to-serial converter at the encoder outputs. |
| FILED | Monday, January 10, 2005 |
| APPL NO | 11/033371 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Coded data generation or conversion 341/70 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 06, 2006.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2006/fedinvent-patents-20060606.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page