FedInvent™ Patents
Patent Details for Tuesday, December 12, 2006
This page was updated on Sunday, March 26, 2023 at 08:06 PM GMT
Department of Defense (DOD)
| US 07146762 | Leung |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Fee Chan Leung (Hazlet, New Jersey) |
| ABSTRACT | A close quarter combat butt stock and blade apparatus for an assault weapon is provided with a slideable cover for a close quarters combat assembly having a rear bayonet. The close quarters combat assembly is connected to the concealed rear bayonet, has an interior opening that defines a close combat handle and a hand shield and is positioned behind the first pistol grip and first trigger. A second trigger is also built into the interior opening. In a closed position, the slideable cover covers the close quarters combat assembly and the rear bayonet remains concealed within the butt stock. When the slideable cover is in the open position, the rear bayonet is simultaneously extended rearward permitting the military and law enforcement user to thrust the rear bayonet at an opponent attacking from the rear or side. Maintaining the bayonet and close quarters combat position with the firing hand next to the second trigger permits the user to fire the weapon much more quickly than before, which will optimize the handling of the assault weapon during bayonet and close quarters fighting, protect the firing hand during bayonet and close quarters fighting and provide the user the means to fire the weapon during bayonet and close quarters fighting. Other embodiments include an assault weapon, an assault rifle, an assault weapon equipped with a close quarters combat assembly and a method for rapidly sliding a slideable cover of an assault weapon and extending a rear bayonet behind a user. |
| FILED | Tuesday, August 24, 2004 |
| APPL NO | 10/925336 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Firearms 042/86 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07146816 | Anderson et al. |
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| ASSIGNEE(S) | Honeywell International, Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Morris G. Anderson (Mesa, Arizona); Hiroshi Kawamura (Glendale, Arizona); Luis M. Flamand (Phoenix, Arizona) |
| ABSTRACT | A combustor liner for shielding an engine from heat generated in a combustion zone includes a sheet with a cool surface for intercepting a cooling air stream and a hot surface enclosing the combustion zone, the combustor liner further including an array of effusion holes extending from the cool surface to the hot surface to allow a portion of the cooling air stream to pass through the effusion holes into the combustion zone, where a portion of the array includes a plurality of upstream-pointed effusion holes oriented such that each upstream-pointed effusion hole has an orientation obtuse to a direction of main flow in the combustion zone so as to control the momentum of cooling air passing into the combustion zone. |
| FILED | Monday, August 16, 2004 |
| APPL NO | 10/919663 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/772 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147436 | Suciu et al. |
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| ASSIGNEE(S) | United Technologies Corporation (Hartford, Connecticut) |
| INVENTOR(S) | Gabriel L. Suciu (Glastonbury, Connecticut); James W. Norris (Lebanon, Connecticut) |
| ABSTRACT | A gas turbine engine has a rotor stack carried by a central shaft. A number of retainer segments each have a first surface engaging the rotor stack and a second surface engaging the central shaft so as to transmit a precompression force from the central shaft to the rotor stack. |
| FILED | Thursday, April 15, 2004 |
| APPL NO | 10/825256 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary kinetic fluid motors or pumps 415/216.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147472 | Habersat et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | James D. Habersat (Woodbridge, Virginia); Brian C. Redman (Silver Springs, Maryland); Jonathan S. Lei (Springfield, Virginia); John E. Nettleton (Fairfax Station, Virginia); Michael M. Quarles (Stafford, Virginia) |
| ABSTRACT | A system, called the Laser Aim Scoring System, and method for automatically scoring gunner training sessions for simulated laser-guided missile, target engagements using the laser designator without the need for training or tactical rounds are disclosed. In the disclosed invention, a pop-up target and its surrounds are separately monitored for radiations at the laser designator frequency. “Hit” or “Miss” scoring is based on detection of the laser radiation at the laser designator frequency illuminating the appropriate region around or on the target at the appropriate time with respect to a simulated missile launch signal at the start of the training engagement, in accordance with the engagement profile programmed into the scoring computer prior to the start of training. The laser aim scoring system send a signal to lower the pop-up target in response to a “Hit” score, and if desired by the user, also sends a signal to initiate smoke and flash signals from a Hoffman Kill Simulator interfaced with the system. The disclosed invention also sends the appropriate signals at the end of the engagement to reset the target in the upright position so that it is ready for the next engagement. The disclosed invention includes subsystems for transmitting data, video imagery, and control signals between the portion of the system at the target location and the portion of the system at the control tower. |
| FILED | Thursday, October 23, 2003 |
| APPL NO | 10/691455 |
| ART UNIT | 3714 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Education and demonstration 434/16 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147687 | Mirkin et al. |
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| ASSIGNEE(S) | Nanosphere, Inc. (Northbrook, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Yun-Wei Cao (Evanston, Illinois); Rongchao Jin (Evanston, Illinois) |
| ABSTRACT | The present invention relates composite core/shell nanoparticles and a two-step method for their preparation. The present invention further relates to biomolecule-core/shell nanoparticle conjugates and methods for their preparation. The invention also relates to methods of detection of biomolecules comprising the biomolecule-core/shell nanoparticle conjugates. |
| FILED | Wednesday, May 22, 2002 |
| APPL NO | 10/153483 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/343 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147715 | Malta et al. |
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| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | David Phillip Malta (Raleigh, North Carolina); Jason Ronald Jenny (Raleigh, North Carolina); Hudson McDonald Hobgood (Pittsboro, North Carolina); Valeri F. Tsvetkov (Durham, North Carolina) |
| ABSTRACT | A method is disclosed for producing semi-insulating silicon carbide crystal with a controlled nitrogen content. The method includes the steps of introducing an ambient gas containing hydrogen into a sublimation growth chamber, heating a silicon carbide source powder to sublimation in the hydrogen ambient growth chamber while, heating and then maintaining a silicon carbide seed crystal in the hydrogen ambient growth chamber to a second temperature below the temperature of the source powder, at which second temperature sublimed species from the source powder will condense upon the seed crystal, continuing to heat the silicon carbide source powder until a desired amount of silicon carbide crystal growth has occurred upon the seed crystal, while maintaining an ambient concentration of hydrogen in the growth chamber sufficient to minimize the amount of nitrogen incorporated into the growing silicon carbide crystal, and while maintaining the source powder and the seed crystal during sublimation growth at respective temperatures high enough to increase the number of point defects in the growing crystal to an amount that renders the resulting silicon carbide crystal semi-insulating. |
| FILED | Monday, July 28, 2003 |
| APPL NO | 10/628189 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/109 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147818 | Rigas et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Elias J. Rigas (Newark, Delaware); Thomas J. Mulkern (Baltimore, Maryland) |
| ABSTRACT | A vacuum assisted resin transfer molding (VARTM) process wherein a preform, release film, distribution medium layer, resin inlet(s), vacuum outlet(s), and vacuum bag(s) are positioned on a mold. After the resin has fully impregnated the preform by a vacuum process, the resin feed source is closed and a vacuum crossover line is opened. The resin inlet(s) are then used as a vacuum source to continue the process of removal of the excess resin. Further, secondary vacuum outlets may be placed on the preform to aid in the removal of excess resin after resin impregnation. This imposes a uniform vacuum pressure across the preform to improve the structural characteristics such as the fiber volume fraction and the compaction of the wetted preform over the conventional VARTM process. |
| FILED | Thursday, May 16, 2002 |
| APPL NO | 10/146055 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/510 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147894 | Zhou et al. |
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| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Otto Z. Zhou (Chapel Hill, North Carolina); Hideo Shimoda (Chapel Hill, North Carolina); Soojin Oh (Chapel Hill, North Carolina) |
| ABSTRACT | A method for the self assembly of a macroscopic structure with a pre-formed nano object is provided. The method includes processing a nano object to a desired aspect ratio and chemical functionality and mixing the processed nano object with a solvent to form a suspension. Upon formation of the suspension, a substrate is inserted into the suspension. By either evaporation of the solvent, changing the pH value of the suspension, or changing the temperature of the suspension, the nano objects within the suspension deposit onto the substrate in an orientational order. In addition, a seed crystal may be used in place of the substrate thereby forming single-crystals and free-standing membranes of the nano-objects. |
| FILED | Monday, March 25, 2002 |
| APPL NO | 10/103803 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating processes 427/256 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147966 | Ren et al. |
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| ASSIGNEE(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Zhifeng Ren (Newton, Massachusetts); Jian Wen (Newton, Massachusetts); Jinghua Chen (Chestnut Hill, Massachusetts); Zhongping Huang (Belmont, Massachusetts); Dezhi Wang (Wellesley, Massachusetts) |
| ABSTRACT | The present invention provides conductive carbon nanotube (CNT) electrode materials comprising aligned CNT substrates coated with an electrically conducting polymer, and the fabrication of electrodes for use in high performance electrical energy storage devices. In particular, the present invention provides conductive CNTs electrode material whose electrical properties render them especially suitable for use in high efficiency rechargeable batteries. The present invention also provides methods for obtaining surface modified conductive CNT electrode materials comprising an array of individual linear, aligned CNTs having a uniform surface coating of an electrically conductive polymer such as polypyrrole, and their use in electrical energy storage devices. |
| FILED | Wednesday, November 27, 2002 |
| APPL NO | 10/305804 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/209 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147967 | Read |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Jeffrey A. Read (West Friendship, Maryland) |
| ABSTRACT | Disclosed is a cathode material for a metal-oxygen battery such as a lithium-oxygen battery. The material comprises, on a weight basis, a first component which is an oxide or a sulfide of a metal. The first component is capable of intercalating lithium, and is present in an amount which is greater than 20% and up to 80% of the material. The material includes a second component which comprises carbon. The carbon is an electroactive catalyst which is capable of reducing oxygen, and comprises 10–80% of the material. The material further includes a binder, such as a fluoropolymer binder, which is present in an amount of 5–40%. Also disclosed is a battery which incorporates the cathode material. |
| FILED | Tuesday, July 29, 2003 |
| APPL NO | 10/628435 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/217 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148017 | Craighead et al. |
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| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Harold G. Craighead (Ithaca, New York); Bojan Ilic (Ithaca, New York); David Alan Czaplewski (Ithaca, New York); Robert H. Hall (Clarksville, Maryland) |
| ABSTRACT | A system and method for detecting mass based on a frequency differential of a resonating micromachined structure, such as a cantilever beam. A high aspect ratio cantilever beam is coated with an immobilized binding partner that couples to a predetermined cell or molecule. A first resonant frequency is determined for the cantilever having the immobilized binding partner. Upon exposure of the cantilever to a solution that binds with the binding partner, the mass of the cantilever beam increases. A second resonant frequency is determined and the differential resonant frequency provides the basis for detecting the target cell or molecule. The cantilever may be driven externally or by ambient noise. The frequency response of the beam can be determined optically using reflected light and two photodetectors or by interference using a single photodetector. |
| FILED | Tuesday, November 14, 2000 |
| APPL NO | 09/712795 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148074 | Drost et al. |
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| ASSIGNEE(S) | Sun Microsystems, Inc. (Santa Clara, California) |
| INVENTOR(S) | Robert J. Drost (Mountain View, California); Ronald Ho (Mountain View, California); Robert J. Proebsting (Sonora, California) |
| ABSTRACT | One embodiment of the present invention provides a system that measures alignment between a first semiconductor die and a second semiconductor die. The system operates by applying a pattern of voltage signals to a two-dimensional array of conductive transmitter elements that form a transmitter array on the first semiconductor die. This transmitter array is positioned over a corresponding two-dimensional array of conductive receiver elements that form a receiver array on the second semiconductor die, whereby a voltage signal applied to a transmitter element induces a voltage signal in one or more receiver elements. The system amplifies voltage signals induced in receiver elements in the receiver array, and subsequently analyzes the amplified signals to determine an alignment between the first semiconductor die and the second semiconductor die. |
| FILED | Wednesday, April 07, 2004 |
| APPL NO | 10/820662 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/15 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148134 | Manning |
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| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Monte Manning (Kuna, Idaho) |
| ABSTRACT | A semiconductor processing method of forming a plurality of conductive lines includes, a) providing a substrate; b) providing a first conductive material layer over the substrate; c) providing a first insulating material layer over the first conductive layer; d) etching through the first insulating layer and the first conductive layer to the substrate to both form a plurality of first conductive lines from the first conductive layer and provide a plurality of grooves between the first lines, the first lines being capped by first insulating layer material, the first lines having respective sidewalls; e) electrically insulating the first line sidewalls; and f) after insulating the sidewalls, providing the grooves with a second conductive material to form a plurality of second lines within the grooves which alternate with the first lines. Integrated circuitry formed according to the method, and other methods, is also disclosed. |
| FILED | Monday, August 09, 2004 |
| APPL NO | 10/914932 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/597 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148361 | Lindsey et al. |
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| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina); ZettaCore, Inc. (Englewood, Colorado) |
| INVENTOR(S) | Jonathan S. Lindsey (Raleigh, North Carolina); Robert S. Loewe (Morrisville, North Carolina); Kannan Muthukumaran (Raleigh, North Carolina); Arounaguiry Ambroise (Cary, North Carolina) |
| ABSTRACT | A method of making a phosphono-substituted dipyrromethane comprises reacting an aldehyde or acetal having at least one phosphono group substituted thereon with pyrrole to produce a phosphono-substituted dipyrromethane; and wherein the phosphono is selected from the group consisting of dialkyl phosphono, diaryl phosphono, and dialkylaryl phosphono. Additional methods, intermediates and products are also described. |
| FILED | Friday, October 31, 2003 |
| APPL NO | 10/698255 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/413 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148416 | Rice |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James Q. Rice (Newport, Rhode Island) |
| ABSTRACT | An undersea vehicle having both low emitted noise and low reflectivity is provided. The undersea vehicle has a hollow cylindrical hull with all components, sensors, electronics, motors, and other internal components with the exception of the propellers, located within the shell of the cylindrical hull. The hollow center of the hull provides a duct and propeller configuration with the shaping of the inlet tube designed to reduce forward noise transmissions, such as reflected active sonar signals and emitted noise. The internal duct gradually constricts to a throat section and thereafter diverges to an output section where dual counter-rotating propellers are located. The result is that most of the internal turbulent flow and the propeller noise is located behind the throat and is thereby reflected in the aft direction. Steering of the vehicle is accomplished by canting the leading edge intake section and the duct exhaust section. |
| FILED | Thursday, August 31, 1995 |
| APPL NO | 08/528624 |
| ART UNIT | 3643 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ships 114/20.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148480 | Zhan et al. |
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| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Guodong Zhan (Davis, California); Amiya K. Mukherjee (Davis, California); Subhash H. Risbud (Davis, California) |
| ABSTRACT | Optical windows for protecting infrared sensing instruments are manufactured from nano-sized crystallites by compressing the crystallites into a continuous mass under high pressure in the presence of a pulsed electric current, preferably one produced by spark plasma sintering. The resulting materials have excellent optical and mechanical properties that make them favorable as replacements for the conventional single-crystal sapphire. |
| FILED | Wednesday, July 14, 2004 |
| APPL NO | 10/892517 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/338.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148496 | Menon et al. |
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| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Rajesh Menon (Cambridge, Massachusetts); Dario Gil (Pleasantville, New York); George Barbastathis (Boston, Massachusetts); Henry I. Smith (Sudbury, Massachusetts) |
| ABSTRACT | A system and method are disclosed for providing error correction in an imaging system. The system includes an error determination unit for determining an amount of error associated with a spot at (x,y) in a binary pattern to be imaged, a determination unit for determining the location of a nearest exposed spot at (xi, yi) for each spot at (x,y), and a dose modification unit for modifying an exposure dose at the nearest exposed spot at (xi, yi) for each spot at (x,y). |
| FILED | Tuesday, April 13, 2004 |
| APPL NO | 10/823458 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/492.220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148600 | Lynch et al. |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | William A. Lynch (Philadelphia, Pennsylvania); Wayne Marks, Jr. (Suldersville, Maryland); Neal A. Sondergaard (Severna Park, Maryland) |
| ABSTRACT | An annular stator holder within a homopolar motor housing is positioned within magnetic fields established by magnet coils positioned in surrounding relation to brushes in sliding contact with the motor rotor. Also enclosed within the stator holder is a slip ring preassembled with the brushes attached thereto on one side by soft-solder joints with the other side attached by hard-solder joints to spring devices for clamping to the stator holder by leaf springs to exert pressure on the brushes thereby maintained in sliding contact with the rotor. |
| FILED | Thursday, June 03, 2004 |
| APPL NO | 10/863844 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/178 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148691 | Nelson et al. |
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| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Carl V. Nelson (Derwood, Maryland); Charles B. Cooperman (Highland, Maryland) |
| ABSTRACT | A device and method to improve pulse inductive metal detector (MD) sensitivity uses multiple, current steps to reduce the voltage rating of electronic components. Current reduction in one implementation is done with multiple switched resistors coupled to a voltage source and connected to the transmitter coil. The current reduction in another implementation is done with multiple switched current sources that are connected to the transmitter coil and are switched inactive one by one to reduce the total current to the transmitter coil. The current is stepped down in rapid secession with a time delay between current transitions less than the time constant of the metal target under investigation. |
| FILED | Thursday, September 16, 2004 |
| APPL NO | 10/942160 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148694 | Stabler |
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| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Martin L. Stabler (Lutz, Florida) |
| ABSTRACT | A contact impedance test circuit for testing impedance between a first contact element and a second contact element comprising an AC signal source for applying an AC signal voltage to the first contact element, an AC contact voltage being emitted by the second contact element, an AC amplifier connected to the second contact element for amplifying the AC contact voltage from the second contact element, an amplified AC contact voltage being produced by the AC amplifier, and a phase angle voltmeter for detecting phase difference between the amplified AC contact voltage and the AC signal voltage at an instance of time, the AC. signal voltage being applied to a reference input of the phase angle voltmeter, the amplified AC contact voltage being applied to a signal input of the phase angle voltmeter. |
| FILED | Friday, June 03, 2005 |
| APPL NO | 11/148571 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/421 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148772 | Sherrer et al. |
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| ASSIGNEE(S) | Rohm and Haas Electronic Materials LLC (Marlborough, Massachusetts) |
| INVENTOR(S) | David W. Sherrer (Radford, Virginia); John J. Fisher (Blacksburg, Virginia) |
| ABSTRACT | Provided are coaxial waveguide microstructures. The microstructures include a substrate and a coaxial waveguide disposed above the substrate. The coaxial waveguide includes: a center conductor; an outer conductor including one or more walls, spaced apart from and disposed around the center conductor; one or more dielectric support members for supporting the center conductor in contact with the center conductor and enclosed within the outer conductor; and a core volume between the center conductor and the outer conductor, wherein the core volume is under vacuum or in a gas state. Also provided are methods of forming coaxial waveguide microstructures by a sequential build process and hermetic packages which include a coaxial waveguide microstructure. |
| FILED | Thursday, December 22, 2005 |
| APPL NO | 11/316417 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Wave transmission lines and networks 333/243 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148835 | Bricker et al. |
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| ASSIGNEE(S) | Lockheed Martin Corporation (Bethesda, Maryland) |
| INVENTOR(S) | Jeffrey K. Bricker (Apalachin, New York); Anthony J. Gounalis (Endicott, New York); James C. Rosswog (Endicott, New York); Stephen P. Wanchissen (Endicott, New York) |
| ABSTRACT | A method and apparatus for evaluating whether one or more threat sources is actively tracking an object, such as an aircraft. A tracking system may analyze information regarding signals received from a source and provide a track indication that the source is actively tracking the object without adjusting the dwell arrangement of the scan strategy of the receiver. A track indication may be provided where a sample count of signal intercepts from the source is greater than a track count during a window. A break track indication representing that the source is not actively tracking the object may be provided when a number of signal intercepts from the source is less than a break track count during a window. |
| FILED | Friday, June 24, 2005 |
| APPL NO | 11/166405 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148842 | Crowne et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Frank Crowne (Laurel, Maryland); Steve C. Tidrow (Silver Spring, Maryland) |
| ABSTRACT | A delay line is made by sandwiching a thin slice of ferroelectric between two “cladding” layers of relatively low-ε, low loss material to form a dielectric slab waveguide, and may support the propagation of electromagnetic guided waves and hence be used as a source of electric-field tunable time delay. There is a frequency range within which a dielectric-slab delay line behaves like a homogeneous transmission line with an “average” dielectric constant that is much lower than that of the ferroelectric, thereby ameliorating the difficulty with the high dielectric constant of the ferroelectric material. The thin slice of ferroelectric material “expels” a large fraction of the wave electric field, causing most of it to occupy the low-loss cladding material, greatly reducing the propagation loss along the delay line while allowing delay time to be varied by applying an electric-field through the ferroelectric within the cladding structure. |
| FILED | Tuesday, February 03, 2004 |
| APPL NO | 10/769850 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/175 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148855 | Homer et al. |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Robert S. Homer (San Diego, California); Robbi Mangra (San Diego, California); Hale B. Simonds (Santee, California) |
| ABSTRACT | A concave tapered slot antenna. The antenna includes a first antenna element, a second antenna element and a concave dielectric lens. The first and second antenna elements are situated in a tapered slot antenna configuration. The concave dielectric lens is situated between said first and second antenna elements so that a 3 dB beamwidth for selected frequencies is increased. A method for fabricating concave tapered slot antennas is also described. |
| FILED | Tuesday, August 31, 2004 |
| APPL NO | 10/932646 |
| ART UNIT | 2821 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Radio wave antennas 343/767 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148967 | Slagle |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Glenn B. Slagle (McLean, Virginia) |
| ABSTRACT | The invention employs a linear variable interference filter, which can be manually moved back and forth along its long axis in front of a slit parallel to its short axis. Thus, the filter pass-band varies linearly from 4,000 angstroms to 10,000 angstroms with a pass-band half-width no greater than 65 angstroms. Therefore, this combination of filter and slit can be placed in front of a charge coupled device (CCD) or other electro-optical imaging device and real time images can be taken as the filter is slid back and forth. Magnifying optics, beam-splitters and scale illuminators can be used to make the scale visible within the field of view of the camera imager. Or, as a simpler embodiment, the graduated image scale could in the form of a hologram of a graduated image scale taken at distance consistent with the desired depth of focus of the camera/imager. |
| FILED | Tuesday, June 21, 2005 |
| APPL NO | 11/158356 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/419 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148968 | Codner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Eric P. Codner (Madison, Wisconsin); Robert M. Corn (Madison, Wisconsin) |
| ABSTRACT | A surface plasmon resonant device provides practical portable operation through the use of a low power high efficiency LED source and a high-efficiency prism sample cell pre-loaded with probe molecules and sealed for field use. A simple mechanical control allows adjustment of angulation of the light and camera for accurate response outside of the laboratory. |
| FILED | Thursday, April 10, 2003 |
| APPL NO | 10/411583 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/445 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149106 | Mancoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Freescale Semiconductor, Inc. (Austin, Texas) |
| INVENTOR(S) | Frederick B. Mancoff (Tempe, Arizona); Bradley N. Engel (Chandler, Arizona); Nicholas D. Rizzo (Gilbert, Arizona) |
| ABSTRACT | A magnetic random access memory (“MRAM”) device can be selectively written using spin-transfer reflection mode techniques. Selectivity of a designated MRAM cell within an MRAM array is achieved by the dependence of the spin-transfer switching current on the relative angle between the magnetizations of the polarizer element and the free magnetic element in the MRAM cell. The polarizer element has a variable magnetization that can be altered in response to the application of a current, e.g., a digit line current. When the magnetization of the polarizer element is in the natural default orientation, the data in the MRAM cell is preserved. When the magnetization of the polarizer element is switched, the data in the MRAM cell can be written in response to the application of a relatively low write current. |
| FILED | Friday, October 22, 2004 |
| APPL NO | 10/971741 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/158 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149147 | Goldman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Geoffrey H. Goldman (Ellicott City, Maryland); Tung-Duong Tran-Luu (Potomac, Maryland) |
| ABSTRACT | One embodiment of the system is implemented as an aircraft comprising a rotor. For example, the aircraft may be a helicopter. This embodiment also comprises an acoustic source, wherein this acoustic source comprises an acoustic signature of the aircraft. This particular embodiment also comprises an acoustic collection device affixed to the aircraft. The acoustic collection device preferably comprises an array of microphones. Finally, this embodiment also has a data processing device, such as a computer, for collecting the data detected by the microphones and processing this data. In operation, the aircraft is flown for a distance along a path while the aircraft emits acoustic energy. Then, the microphones detect the acoustic energy that is reflected off the terrain. Optionally, the detected energy may be stored as data and processed, so that noise may be reduced and a terrain image may be formed. |
| FILED | Thursday, September 02, 2004 |
| APPL NO | 10/932252 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/88 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149148 | Berkman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | BBN Technologies Corp. (Cambridge, Massachusetts) |
| INVENTOR(S) | Evan Frank Berkman (Newton Centre, Massachusetts); Paul D. Koenigs (Matunuck, Rhode Island) |
| ABSTRACT | The selection of multiple, suitably designed, demodulation reference signals can enable the measurement of a vehicle's speed using continuously transmitted frequency modulated (CTFM) signals. The unique solution of vehicle speed can be used to resolve the range Doppler ambiguity found in conventional CTFM sonar and radar systems. This can enable continuous range and speed estimates of high-speed vehicles with an attendant reduction in transmit power relative to pulse-echo systems with similar measures of performance due to the 100% duty cycle. |
| FILED | Thursday, March 25, 2004 |
| APPL NO | 10/809005 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149149 | Sullivan |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Edmund J. Sullivan (Portsmouth, Rhode Island) |
| ABSTRACT | The present invention relates to a system and a method for substantially eliminating flow noise from the signal output of each hydrophone in a hull mounted acoustic array. The system comprises a plurality of hydrophones forming an acoustic array mounted to a hull of a marine vessel, at least one reference hydrophone mounted to the hull in a laminar region of fluid flow over the hull, and a computational device for generating an output signal for each hydrophone in the acoustic array which is substantially free of flow noise using signals inputted from the acoustic array hydrophones and the at least one reference hydrophone. |
| FILED | Friday, October 05, 2001 |
| APPL NO | 09/972295 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/126 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149150 | Scarzello et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John F. Scarzello (Columbia, Maryland); John J. Holmes (Columbia, Maryland); Edward C. O'Keefe (Columbia, Maryland); Robert A. Wingo (Manassas, Virginia) |
| ABSTRACT | A plurality of sensing modules are deployed by positioning thereof in spaced relation to each other on a seafloor surface at a shallow depth to establish a targeted seawater zone within which certain conditions are detected, such as those produced by the presence of a sea vessel such as a submarine within the targeted zone. Data signals are generated within the deployed sensing modules in response to said detection of the submarine for radio frequency transmission above the seawater targeted zone from floating transmitters ejected from the sensing modules positioned on the seafloor surface after detection of the submarine. |
| FILED | Thursday, May 26, 2005 |
| APPL NO | 11/151182 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/149 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149335 | Kaufhold |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | John Patrick Kaufhold (Altamont, New York) |
| ABSTRACT | A method for facilitating an enhancement of a visibility of an object in an x-ray image includes generating an x-ray image including at least one object, generating an estimate of a background surrounding the at least one object, subtracting the background estimate from the x-ray image to generate an estimate of pixel intensities due the object, mapping the estimate of pixel intensities due to the object, and combining the mapped estimate of pixel intensities due to the object and the x-ray image to generate an enhanced image. |
| FILED | Friday, September 27, 2002 |
| APPL NO | 10/256779 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/132 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149374 | Lagakos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Nicholas Lagakos (Silver Spring, Maryland); Joseph A. Bucaro (Herdon, Virginia); Jacek Jarzynski (Bethesda, Maryland) |
| ABSTRACT | A fiber optic pressure sensor includes an optical fiber for transmitting light. The optical fiber has an axis. The fiber optic pressure sensor also includes an etched diaphragm perpendicular to the axis. The diaphragm includes an operative side located at a distance from the optical fiber sufficient to reflect a portion of the transmitted light into the optical fiber. The etched diaphragm includes a semiconductor, a dielectric, and/or a metal. |
| FILED | Tuesday, August 24, 2004 |
| APPL NO | 10/927650 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149562 | Walker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Steven C. Walker (Waxahachie, Texas); John M. Shepherd (San Antonio, Texas); Leopoldo C. Cancio (San Antonio, Texas) |
| ABSTRACT | A needle with fiber optic capability for spectrophotometric analysis includes a needle assembly including a needle body having an open tip and side radiation ports. A fiber optic element is disposed in the needle assembly for carrying electromagnetic radiation to the open tip area for transmission to a target area. Fiber optic bundles in communication with the radiation ports are disposed in the needle body for transmitting backscattered radiation to a light detector or sensor for spectrophotometric analysis. The needle assembly may include barbs for anchoring the device in place. |
| FILED | Wednesday, September 17, 2003 |
| APPL NO | 10/663684 |
| ART UNIT | 3768 — Optics |
| CURRENT CPC | Surgery 6/339 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149652 | O'Kane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Barbara L. O'Kane (Franconia, Virginia); Gary L. Page (Clifton, Virginia); David L. Wilson (Fredericksburg, Virginia) |
| ABSTRACT | The methods for determining the probability of detection of a thermally camouflaged target at various ranges by the sensor includes determining an “inherent” temperature difference, ΔTRSS, between the target and its immediate surroundings. Once ΔTRSS is determined, a scaled N50 cycle criterion, or the number of resolvable cycles needed by the sensor for a fifty percent probability of detection, is determined according to the relationship N50=A/(ΔTRSS)B+C, where A, B and C are constants that are predetermined according to whether the immediate surroundings are of a woodland or a littoral nature. The scaled N50 cycle criterion is then used in an empirical Target Transfer Probability Function (TTPF) defined by P=(N/N50)E/(1+(N/N50)E), where E=2.7+0.7(N/N50), in order to determine the probability of detection of the thermally camouflaged target. |
| FILED | Tuesday, December 21, 2004 |
| APPL NO | 11/016861 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/181 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149684 | Ahroon |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | William A. Ahroon (Enterprise, Alabama) |
| ABSTRACT | An improved method and system for performing speech reception threshold testing includes calibrating one or more recorded spoken words to have substantially the same sound energy and presenting the one or more calibrated recorded spoken words to a test subject. A speech reception threshold of the test subject is measured by utilizing the one or more calibrated recorded spoken words wherein the speech reception threshold measured is indicative of a sound level at which the test subject can recognize the presented recorded spoken word or words. |
| FILED | Tuesday, December 18, 2001 |
| APPL NO | 10/025045 |
| ART UNIT | 2626 — Selective Visual Display Systems |
| CURRENT CPC | Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression 74/224 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149897 | Chincheck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Stanley Chincheck (Alexandria, Virginia); Myong Hoon Kang (Fairfax, Virginia); Ira S Moskowitz (Washington, District of Columbia); Jim Parsonese (Apex, North Carolina) |
| ABSTRACT | In a communication system having a plurality of networks, a method of achieving network separation between first and second networks is described. First and second networks with respective first and second degrees of trust are defined, the first degree of trust being higher than the second degree of trust. Communication between the first and second networks is enabled via a network interface system having a protocol stack, the protocol stack implemented by the network interface system in an application layer. Data communication from the second network to the first network is enabled while data communication from the first network to the second network is minimized. |
| FILED | Friday, July 25, 2003 |
| APPL NO | 10/627102 |
| ART UNIT | 2131 — Selective Visual Display Systems |
| CURRENT CPC | Electrical computers and digital processing systems: Support 713/166 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE39428 | Keller et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Teddy M. Keller (Fairfax Station, Virginia); Craig Homrighausen (Longmont, Colorado) |
| ABSTRACT | A linear polymer has repeating units represented by the formula wherein (a) n is an integer greater than or equal to 0, (b) x is an integer greater than or equal to 1, and represents an unconjugated acetylenic group when x is equal to 1 or conjugated acetylenic groups when x is greater than 1; (c) Ar is an aromatic group, and (c) R1, R2, R3, R4, R5, R6, R7 and R8 are independently selected from the group consisting of alkyl, aryl, alkylaryl, haloalkyl, haloaryl and mixtures thereof. The linear polymer may be thermally cured to form a crosslinked polymer. |
| FILED | Thursday, March 25, 2004 |
| APPL NO | 10/817440 |
| ART UNIT | 1712 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Synthetic resins or natural rubbers 525/477 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 07147329 | Berger, legal representative et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees Of The University Of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Karen R. Berger, legal representative (Cherry Hill, New Jersey); Richard A Stone (Havertown, Pennsylvania) |
| ABSTRACT | The invention includes a computer-implemented method, system, and computer-readable medium having computer-executable modules for judging changes in components of an eye. The inventive computer-implemented method includes the steps of acquiring, displaying, and superimposing at least two digital images of the components of the eye. The method further includes the step of processing at least one of the digital images such that the superimposed images may be compared, and the step of flickering among the superimposed digital images. The step of acquiring the images may include the step of converting a photographic representation of the components of the eye to the digital image. The step of processing may include registering, warping, and/or aligning the digital images. |
| FILED | Wednesday, January 21, 2004 |
| APPL NO | 10/761606 |
| ART UNIT | 3762 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Optics: Eye examining, vision testing and correcting 351/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147625 | Sarangapani et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | ICET, Inc. (Norwood, Massachusetts) |
| INVENTOR(S) | Shantha Sarangapani (Walpole, Massachusetts); Fletcher Tifft Longley (Westwood, Massachusetts) |
| ABSTRACT | An accessory is connected between a leg bag and a urinary catheter to prevent microorganisms migrating from the leg bag up through the catheter. The accessory has a sleeve, connectors to connect the sleeve to the leg bag and to the urinary catheter, a filter positioned within the sleeve that can be coated with an antimicrobial composition, and a valve to prevent fluid from moving from the leg bag to the catheter. The antimicrobial coated sleeve can be used with or with out the filter. The filter is made by compounding a polymeric resin powder with an antimicrobial composition. |
| FILED | Tuesday, July 01, 2003 |
| APPL NO | 10/611301 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Surgery 64/317 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147800 | Wellinghoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Southwest Research Institute (San Antonio, Texas) |
| INVENTOR(S) | Stephen T. Wellinghoff (San Antonio, Texas); Douglas P. Hanson (San Antonio, Texas) |
| ABSTRACT | A method for making platform molecules comprising: reacting 4-alkoxy benzoyl chloride with R2-hydroquinone under first conditions effective to produce bis 1,4[4-alkoxy-benzoyloxy]-R2-phenylene comprising bis terminal alkoxy groups wherein R2 is a bulky organic group; and, subjecting the bis 1,4[4-alkoxy-benzoyloxy]-R2-phenylene to second conditions effective to selectively cleave the bis terminal alkoxy groups to produce a solution comprising complexes comprising diphenolic platform molecules comprising bis terminal hydroxyl groups, the second conditions also being effective to precipitate the complexes out of the solution. |
| FILED | Wednesday, December 24, 2003 |
| APPL NO | 10/746109 |
| ART UNIT | 1756 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compositions 252/299.670 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147840 | Pandey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Health Research, Inc. (Buffalo, New York) |
| INVENTOR(S) | Ravindra K. Pandey (Williamsville, New York); Andrei Kozyrev (Goleta, California); Xiang Zheng (Cheektowaga, New York) |
| ABSTRACT | A compound having the structural formula: where R is H or lower alkyl of 1 through 12 carbon atoms. In general, the compounds of the invention are 132-Oxo-bacteriopyropheophorbide—a carboxylic acid and C1–C12 alkyl esters thereof. A method for the preparation of the carboxylic acid compounds of the invention includes the step of reacting bacteriopyropheophorbide—a alkyl ester with lithium hydroxide tetrahydrofuran and water. A method of the invention for the preparation of the C1–C12 alkyl ester compounds of the invention includes the steps of reacting bacteriopyropheophorbide—a alkyl, especially methyl, ester with lithium hydroxide in tetrahydrofuran and water to obtain 132-Oxo-bacterio-pyropheophobide-a carboxylic acid followed by reacting the carboxylic acid with an acid chloride producing reagent to obtain the 132-Oxo-bacterio pyropheophobide-a acid chloride (compound 5) and reacting the 132-Oxo-bacterio pyropheophobide-a acid chloride with a C1–C12 alcohol to obtain a 132-Oxo-bacterio-pyropheophobide-a carboxylic acid C1–C12 alkyl ester (compound 6). The compounds of the invention may be used as long wavelength absorbing photosensitizers for photodynamic therapy. |
| FILED | Friday, February 25, 2005 |
| APPL NO | 11/066511 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.362 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147848 | Gromeier et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Albany, New York) |
| INVENTOR(S) | Matthias Gromeier (Stony Brook, New York); Eckard Wimmer (East Setauket, New York) |
| ABSTRACT | The present invention is directed to non-pathogenic, oncolytic, recombinant polioviruses for the treatment of various forms of malignant tumors. The recombinant polioviruses of the invention are those in which the internal ribosomal entry site (IRES) of the wild type poliovirus was exchanged with the IRES of other picornaviruses, and optionally P1, P3 or the 3′NTR thereof was exchanged with that of poliovirus Sabin type. More particularly, the present invention is directed to the administration of the non-pathogenic, oncolytic, recombinant poliovirus to the tumor directly, intrathecally or intravenously to cause tumor necrosis. The method of the present invention is particularly useful for the treatment of malignant tumors in various organs, such as: breast, colon, bronchial passage, epithelial lining of the gastrointestinal, upper respiratory and genito-urinary tracts, liver, prostate and the brain. Astounding remissions in experimental animals have been demonstrated for the treatment of malignant glioblastoma multiforme, an almost universally fatal neoplasm of the central nervous system. |
| FILED | Wednesday, June 19, 2002 |
| APPL NO | 10/175247 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147861 | Compton et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Teresa Compton (Madison, Wisconsin); Mary T. Huber (Portland, Oregon) |
| ABSTRACT | A method of designing a new anti-CMV drug is disclosed. In one embodiment, the invention comprises (a) analyzing the binding of glycoprotein O to a glycoprotein O receptor and (b) designing a candidate drug that would competitively interfere with glycoprotein O binding to glycoprotein O receptor and (c) showing that the candidate drug competitively inhibits glycoprotein O binding to glycoprotein O receptor. A method of screening anti-CMV drugs, a vaccine effective to diminish CMV infection, and a method of diminishing CMV infection are also disclosed. |
| FILED | Wednesday, June 26, 2002 |
| APPL NO | 09/942146 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/204.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148003 | Hunter et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Tony Hunter (Del Mar, California); Kun Ping Lu (Newton, Massachusetts) |
| ABSTRACT | A novel class of NIMA interacting proteins (PIN), exemplified by Pin1, is provided. Pin1 induces a G2 arrest and delays NIMA-induced mitosis when overexpressed, and triggers mitotic arrest and DNA fragmentation when depleted. Methods of identifying other Pin proteins and Pin-interacting proteins and identifying compositions which affect Pin activity or expression are also provided. |
| FILED | Monday, November 17, 2003 |
| APPL NO | 10/716379 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148004 | Friedman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Jeffrey M. Friedman (New York, New York); Gwo-Hwa Lee (New York, New York); Ricardo Proenca (Astoria, New York); Ella Ioffe (New York, New York) |
| ABSTRACT | The present invention relates to identification of a receptor for a satiety factor, which is involved in body weight homeostasis. Mutations in this receptor are associated with obese phenotypes. In particular, the present invention relates to identification and characterization of the receptor for leptin, including a naturally occurring soluble form of the receptor that is expected to modulate leptin activity, in particular to agonize leptin activity. The invention further relates to the nucleic acids encoding the receptor, and to methods for using the receptor, e.g., to identify leptin analogs, therapeutically, such as in gene therapy or in soluble form as an agonist or antagonist of leptin activity, or diagnostically. |
| FILED | Thursday, January 16, 1997 |
| APPL NO | 08/783734 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148006 | Katze et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Michael G. Katze (Seattle, Washington); Michael J. Gale (Monroe, Washington) |
| ABSTRACT | The present invention relates to novel methods for identifying antiviral agents which selectively interfere with viral proteins that override the interferon(IFN)-induced cellular defense mechanisms against viral infection. In particular, the present invention relates to screening assays that identify agents which selectively inhibit the interaction between viral proteins containing an interferon sensitivity determining region (ISDR) and IFN-induced PKR protein kinase. The present invention more particularly relates to screening assays that identify agents which selectively inhibit the interaction between hepatitis C virus (HCV) nonstructural 5A protein (NS5A), which contains an ISDR, and IFN-induced PKR protein kinase. The interaction between the viral ISDR and IFN-induced PKR protein kinase results in the override of IFN-induced cellular defense mechanisms to combat viral infection. Therefore the agents identified using the assays of the invention may have utility as antiviral agents. |
| FILED | Friday, October 05, 2001 |
| APPL NO | 09/972756 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148009 | Vogelstein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Bert Vogelstein (Baltimore, Maryland); Todd Waldman (Bethesda, Maryland); Christoph Lengauer (Columbia, Maryland); Kenneth W. Kinzler (BelAir, Maryland) |
| ABSTRACT | Checkpoint gene-defective human cells are useful for screening potential anti-tumor agents. Potential therapeutic agents are screened for the ability to cause DNA accumulation or cell death in a checkpoint gene-defective human cell. |
| FILED | Tuesday, December 17, 2002 |
| APPL NO | 10/320639 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148036 | Luyten et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Frank P. Luyten (Rockville, Maryland); Malcolm Moos, Jr. (Bethesda, Maryland); Steven Chao-Huan Chang (Chicago, Illinois) |
| ABSTRACT | The present invention is a purified cartilage extract that stimulates local cartilage formation when combined with a matrix and implanted into a mammal. This extract can conveniently be produced by a method which includes the steps of: obtaining cartilage tissue; homogenizing the cartilage tissue in the presence of chaotropic agents under conditions that permit separation of proteins from proteoglycans; separating the proteins from the proteoglycans and then obtaining the proteins. The step for separating the proteins from the proteoglycans can be carried out using a sepharose column. The extract can also be obtained by additionally including the steps of separating the proteins on a molecular sieve and then collecting the proteins having molecular weights in the 30 kDa to 60 kDa size range. Articular cartilage or epiphyseal cartilage can be used in the preparation of this purified extract. |
| FILED | Friday, May 19, 2000 |
| APPL NO | 09/574819 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148040 | Meagher et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia); Abeome Corporation (Athens, Georgia) |
| INVENTOR(S) | Richard B. Meagher (Athens, Georgia); Vince Laterza (Decatur, Georgia) |
| ABSTRACT | The present invention relates to genetically altered hybridomas, myelomas and B cells. The invention also relates to utilizing genetically altered hybridomas, myelomas and B cells in methods of making monoclonal antibodies. The present invention also provides populations of hybridomas and B cells that can be utilized to make a monoclonal antibody of interest. |
| FILED | Wednesday, February 20, 2002 |
| APPL NO | 10/079130 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/70.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148061 | Lenardo et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Michael J. Lenardo (Bethesda, Maryland); Francis Ka-Ming Chan (Silver Spring, Maryland); Richard M. Siegel (Washington, District of Columbia) |
| ABSTRACT | The present invention provides a polypeptide comprising the isolated amino acid sequence of a pre-ligand assembly domain (PLAD) of a TNF-like receptor. Also provided by this invention is a polypeptide comprising the isolated amino acid sequence of a pre-ligand assembly domain (PLAD), wherein the PLAD is selected from the group consisting of: the PLAD of a TNF-R, the PLAD of p60, the PLAD of p80, the PLAD of Fas (CD95/APO-1), the PLAD of TRAIL receptors, the PLAD of LTβR, the PLAD of CD40, the PLAD of CD30, the PLAD of CD27, the PLAD of HVEM, the PLAD of OX40 and the PLAD of DR4. TNF-R, p60, p80, Fas, TRAIL receptor, LTβR, CD40, CD30, CD27, HVEM, OX40, DR4, TROY, EDAR, XEDAR, DCR3, AITR, 4-1BB, DR3, RANK, TACI, BCMA, DR6, DPG, DR5, DCR1 AND DCR2 are all members of the TNF receptor superfamily or the TNF-like receptor family. The invention also provides the PLAD for other members of the TNF receptor superfamily. The polypeptides of the present invention can be utilized to inhibit oligomerization of members of the TNF receptor superfamily. These polypeptides can also be utilized to inhibit ligand binding to members of the TNF receptor superfamily. The present invention also provides a composition comprising an inhibitor of TNF receptor oligomerization. Further provided by this invention are members of the TNF receptor superfamily that are lacking a PLAD. |
| FILED | Friday, February 09, 2001 |
| APPL NO | 10/203495 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148065 | Bohach |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Idaho Research Foundation, Inc. (Moscow, Idaho) |
| INVENTOR(S) | Gregory I. Bohach (Moscow, Idaho) |
| ABSTRACT | Pyrogenic toxins, such as staphylococcal enterotoxins, modified in the disulfide loop region are provided. The modified toxins retain useful biological properties but have substantially reduced toxicity compared to the corresponding unmodified native toxin. The native pyrogenic toxins are typically modified by deletions within the disulfide loop region to produce modified enterotoxins having 100-fold or greater decrease in toxicity. |
| FILED | Friday, August 20, 2004 |
| APPL NO | 10/923324 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/440 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148067 | Morrissey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | James H. Morrissey (Champaign, Illinois); Stephanie A. Smith (Champaign, Illinois) |
| ABSTRACT | A thromboplastin reagent includes tissue factor, Factor VIIa, and a net negatively charged phospholipid. The thromboplastin reagent is a synthetic thromboplastin reagent, and is in dried form. |
| FILED | Tuesday, August 31, 2004 |
| APPL NO | 10/931282 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/69 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148071 | Oas et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Terence G. Oas (Durham, North Carolina); Sina Ghaemmaghami (Durham, North Carolina); Kendall D. Powell (Durham, North Carolina); Michael C. Fitzgerald (Durham, North Carolina) |
| ABSTRACT | In proteomic research, it is often necessary to screen a large number of polypeptides for the presence of stable structure. Described herein are methods (referred to as MALDI MS-HX and SUPREX) for measuring the stability of proteins in a rapid, high-throughput fashion. The method employs hydrogen exchange to estimate the stability of quantities of unpurified protein extracts, using matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. A method of quantitatively determining the stability of a test protein under native conditions is disclosed. The method includes the steps (a) providing a test protein; (b) contacting the protein with an exchange buffer comprising a denaturant and deuterium, the exchange buffer having a denaturant concentration; (c) contacting the test protein with a mass spectrometry matrix medium; (d) determining a change in mass of the test protein by mass spectrometry; (e) varying the denaturant concentration of the exchange buffer; (f) repeating steps (a)–(e) a desired number of times; and (g) quantitatively determining protein stability based on the change in mass of the test protein as a function of denaturant concentration, whereby the stability of a test protein under native conditions is quantitatively determined. |
| FILED | Thursday, March 18, 2004 |
| APPL NO | 10/807034 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Analytical and immunological testing 436/173 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148197 | Fogelman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The University of Alabama Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Alan M Fogelman (Beverly Hills, California); Gattadahalli M Anantharamaiah (Birmingham, California); Mohamad Navab (Los Angeles, California) |
| ABSTRACT | This invention provides novel peptides for the treatment of atherosclerosis. In certain embodiments the peptide is X1-X2-X3-X4 where X1 and X4 are independently selected from the group consisting of alanine (Ala), valine (Val), leucine (Leu), isoleucine (Ile), proline (Pro), phenylalanine (Phe), tryptophan (Trp), methionine (Met), serine (Ser) bearing a hydrophobic protecting group, beta-naphthyl alanine, alpha-naphthyl alanine, norleucine, cyclohexylalanine, threonine (Thr) bearing a hydrophobic protecting group, tyrosine (Tyr) bearing a hydrophobic protecting group, lysine (Lys) bearing a hydrophobic protecting group, arginine (Arg) bearing a hydrophobic protecting group, ornithine (Orn) bearing a hydrophobic protecting group, aspartic acid (Asp) bearing a hydrophobic protecting group, cysteine (Cys) bearing a hydrophobic protecting group, and glutamic acid (Glu) bearing a hydrophobic protecting group; X2 and X3 are independently selected from the group consisting of Asp, Arg, and Glu; and the peptide converts pro-inflammatory HDL to anti-inflammatory HDL or makes anti-inflammatory HDL more anti-inflammatory. |
| FILED | Tuesday, August 26, 2003 |
| APPL NO | 10/649378 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/18 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148201 | Stern et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Robert Stern (San Francisco, California); Gregory I. Frost (San Francisco, California); Anthony Csóka (San Francisco, California); Tim M. Wong (San Francisco, California) |
| ABSTRACT | The invention is based on the discovery of methods for purification of an acid active hyaluronidase found in human plasma (hpHAse), including both biochemical and immunoaffinity purification methods. The method of immunoaffinity purification of the invention is based on the discovery of a method for identifying antibodies that specifically bind native hpHAse (anti-native hpHAse antibodies), and anti-native hpHAse antibodies identified by this screening method. The invention also features an assay for sensitive detection of HAse activity using biotinylated hyaluronic acid (bHA). Purification and characterization of hpHAse lead to the inventors' additional discovery that hpHAse is encoded by the LuCa-1 gene, which gene is present in the human chromosome at 3p21.3, a region associated with tumor suppression. The invention additionally features methods of treating tumor-bearing patients by administration of hpHAse and/or transformation of cells with hpHAse-encoding DNA. |
| FILED | Tuesday, February 27, 2001 |
| APPL NO | 09/795914 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148203 | Hackett et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Perry B. Hackett (Shoreview, Minnesota); Zoltan Ivics (Berlin, Germany); Zsuzsanna Izsvak (Berlin, Germany) |
| ABSTRACT | This invention relates to a system for introducing nucleic acid into the DNA of a cell. The system includes the use of a member of the SB family of transposases (SB) or nucleic acid encoding the transposase and a nucleic acid fragment that includes a nucleic acid sequence with flanking inverted repeats. The transposase recognizes at least a portion of an inverted repeats and incorporates the nucleic acid sequence into the DNA. Methods for use of this system are discussed. |
| FILED | Wednesday, October 02, 2002 |
| APPL NO | 10/263159 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148223 | Secrist, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Southern Research Institute (Birmingham, Alabama) |
| INVENTOR(S) | John A. Secrist, III (Birmingham, Alabama); Kamal N. Tiwari (Birmingham, Alabama); John A. Montgomery (Birmingham, Alabama) |
| ABSTRACT | Compounds represented by the formula 1: A is selected from the group consisting of wherein each R individually is H or acyl, Y is X, N3, NH2, monoalkylamino, or dialkylamino; Z is O or S; and X is selected from the group consisting of hydrogen, halo, hydroxy, alkoxy, alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, amino, monoalkylamino, dialkylamino, thioaryl, thioalkyl, allylamino, cyano and nitro; tautomers thereof; and pharmaceutically acceptable salts thereof are provided along with methods for their fabrication. Various of these compounds can be used as anticancer agents, or antiviral agents or to inhibit DNA replication. |
| FILED | Monday, January 31, 2005 |
| APPL NO | 11/045085 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/249 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148251 | Shayman |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | James A. Shayman (Ann Arbor, Michigan) |
| ABSTRACT | Novel prodrugs of amino ceramide-like compounds are provided which inhibit glucosyl ceramide (GlcCer) formation by inhibiting the enzyme GlcCer synthase, thereby lowering the level of glycosphingolipids. The compounds of the present invention have improved GlcCer synthase inhibition activity and are therefore highly useful in therapeutic methods for treating various conditions and diseases associated with altered glycosphingolipid levels. |
| FILED | Thursday, January 10, 2002 |
| APPL NO | 10/044869 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/428 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148257 | Bacopoulos et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Merck HDAC Research, LLC (Boston, Massachusetts); Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Nicholas G. Bacopoulos (New York, New York); Judy H. Chiao (Berkeley Heights, New Jersey); Thomas A. Miller (New York, New York); Carolyn M. Paradise (Cortland Manor, New York); Victoria M. Richon (Rye, New York) |
| ABSTRACT | Methods for treating mesothelioma comprising administering the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) are disclosed. |
| FILED | Tuesday, August 26, 2003 |
| APPL NO | 10/650025 |
| ART UNIT | 1614 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/616 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148323 | Schofield et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Darren Schofield (Wantage, United Kingdom); Suzanne U. Emerson (Kensington, Maryland); Robert H. Purcell (Boyds, Maryland) |
| ABSTRACT | The invention describes the identification of a major neutralization site of hepatitis E virus (HEV) and the use of this neutralization site in methods of vaccination and in methods of screening for neutralizing antibodies to HEV. The invention also describes the isolation and characterization of neutralizing chimpanzee monoclonal antibodies reactive to the neutralization site and the use of these antibodies in the diagnosis, treatment and prevention of HEV. |
| FILED | Wednesday, February 09, 2005 |
| APPL NO | 11/054041 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/338.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148325 | Sakalian et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Michael Sakalian (Oklahoma City, Oklahoma); Eric Hunter (Vestavia Hills, Alabama) |
| ABSTRACT | The subject invention provides novel and advantageous methods for identifying amino acid sequences in random peptide libraries that can bind to Gag polypeptides. The subject invention also establishes a novel in vitro system that can be used to test competitive inhibitors of retrovrial capsid assembly. Also provided are peptides, and compositions containing these peptides, which are inhibitors of the retrovirus Gag protein(s) function. Chimeric Gag polypeptides are also provided. |
| FILED | Friday, September 28, 2001 |
| APPL NO | 09/968355 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/350 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148328 | Cheung |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Ambrose Cheung (Hanover, New Hampshire) |
| ABSTRACT | A nucleic acid sequence required for regulating the autolytic activity of bacteria is provided. Also provided are polypeptides encoded by the gene or mutant gene as well as vector and host cells for expressing these polypeptides. Methods for identifying and using agents which interact with the gene or mutant gene or polypeptides encoded thereby to inhibit bacterial growth and infectivity are also provided. |
| FILED | Wednesday, March 06, 2002 |
| APPL NO | 10/469477 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/358 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148333 | Cox, III |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Bolder Biotechnology, Inc. (Boulder, Colorado) |
| INVENTOR(S) | George N. Cox, III (Louisville, Colorado) |
| ABSTRACT | The growth hormone supergene family comprises greater than 20 structurally related cytokines and growth factors. A general method is provided for creating site-specific, biologically active conjugates of these proteins. The method involves adding cysteine residues to non-essential regions of the proteins or substituting cysteine residues for non-essential amino acids in the proteins using site-directed mutagenesis and then covalently coupling a cysteine-reactive polymer or other type of cysteine-reactive moiety to the proteins via the added cysteine residue. Disclosed herein are preferred sites for adding cysteine residues or introducing cysteine substitutions into the proteins, and the proteins and protein derivatives produced thereby. |
| FILED | Wednesday, March 26, 2003 |
| APPL NO | 10/400377 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/399 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148342 | Tolentino et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of the University of Pennyslvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Michael J. Tolentino (Villanova, Pennsylvania); Samuel Jotham Reich (Bala Cynwyd, Pennsylvania) |
| ABSTRACT | RNA interference using small interfering RNAs which are specific for the vascular endothelial growth factor (VEGF) gene and the VEGF receptor genes Flt-1 and Flk-1/KDR inhibit expression of these genes. Diseases which involve angiogenesis stimulated by overexpression of VEGF, such as diabetic retinopathy, age related macular degeneration and many types of cancer, can be treated by administering the small interfering RNAs. |
| FILED | Thursday, November 14, 2002 |
| APPL NO | 10/294228 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148356 | Smith, III et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Milton R. Smith, III (East Lansing, Michigan); Robert E. Maleczka (Dewitt, Michigan) |
| ABSTRACT | A process for producing organic substituted aromatic or heteroaromatic compounds including biaryl and biheteroaryl compounds in a two-step reaction. In the first step, the aromatic or heteroaromatic compound is borylated in a reaction comprising a borane or diborane reagent (any boron reagent where the boron reagent contains a B—H, B—B or B—Si bond) and an iridium or rhodium catalytic complex. In the second step, a metal catalyst catalyzes the formation of the organic substituted aromatic or heteroaromatic compound from the borylated compound and an electrophile such as an aryl or organic halide, triflate (OSO2CF3), or nonaflate (OSO2C4F9). The steps in the process can be performed in a single reaction vessel or in separate reaction vessels. The present invention also provides a process for synthesis of complex polyphenylenes starting from halogenated aromatic compounds. |
| FILED | Monday, March 14, 2005 |
| APPL NO | 11/079672 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/250 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148887 | Kaufman et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Stonybrook, New York) |
| INVENTOR(S) | Arie E. Kaufman (Plainview, New York); Zhengrong Liang (Stony Brook, New York); Mark R. Wax (Greenlawn, New York); Ming Wan (Stony Brook, New York); Dongquing Chen (Stony Brook, New York) |
| ABSTRACT | A system and method for generating a three-dimensional visualization image of an object such as an organ using volume visualization techniques and exploring the image using a guided navigation system which allows the operator to travel along a flight path and to adjust the view to a particular portion of the image of interest in order, for example, to identify polyps, cysts or other abnormal features in the visualized organ. An electronic biopsy can also be performed on an identified growth or mass in the visualized object. Virtual colonoscopy can be enhanced by electronically removing residual stool, fluid and non-colonic tissue from the image of the colon, by employing bowel preparation followed by image segmentation operations. Methods are also employed for virtually expanding regions of colon collapse using image segmentation results. |
| FILED | Wednesday, October 10, 2001 |
| APPL NO | 09/974548 |
| ART UNIT | 2671 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Computer graphics processing and selective visual display systems 345/419 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149586 | Greenberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Second Sight Medical Products, Inc. (Sylmar, California) |
| INVENTOR(S) | Robert Greenberg (Los Angeles, California); Richard Williamson (Saugus, California); Mark Humayan (La Canada, California) |
| ABSTRACT | The present invention is an implantable electrode array having electrodes with variable pitch and variable size. Electrode arrays of the prior art provide electrodes with a common spacing and size. However, this is not how the human body is arranged. As an example, the retina has closely spaced retinal receptors near the fovea. Those receptors are spaced farther apart, farther away from the fovea. Further, the amount of electrical current required to stimulate the perception of light increases with distance from the fovea. Hence, larger electrodes are required to transfer the necessary current farther away from the fovea. |
| FILED | Thursday, March 28, 2002 |
| APPL NO | 10/112801 |
| ART UNIT | 3766 — Optics |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/116 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149631 | Brenner et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Steven E. Brenner (Oakland, California); Richard E. Green (Berkeley, California); Benjamin P. Lewis (Berkeley, California) |
| ABSTRACT | Computational methods identify alternate splice forms of known gene transcripts and isoforms that are subject to NMD (nonsense-mediated decay). These methods were used to identify thousands of human genes that generate alternative splice forms, and to demonstrate that about a third of these are subject to NMD. This high prevalence of NMD-targeted transcripts indicates a systemic way of regulating gene expression—by shunting gene expression to nonproductive splice variants. This endemic regulation is exploited to engineer regulation of gene expression, to characterize splice pathway components and to assay splice environments, for example, using NMD-regulated reporter genes. |
| FILED | Friday, May 31, 2002 |
| APPL NO | 10/159997 |
| ART UNIT | 2168 — Data Bases & File Management |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 07147050 | Kang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Capstone Turbine Corporation (Chatsworth, California) |
| INVENTOR(S) | Yungmo Kang (La Canada Flintridge, California); Robert D. McKeirnan, Jr. (Westlake Village, California) |
| ABSTRACT | A counter-flow recuperator formed from annular arrays of recuperator core segments. The recuperator core segments are formed from two opposing sheets of fin fold material coined to form a primary surface zone disposed between two flattened manifold zones. Each primary surface zone has undulating corrugations including a uniform, full height central portion and a transition zone disposed between the central portion and one of the manifold zones. Corrugations of the transition zone rise from zero adjacent to the manifold zone and increase along a transition length to full crest height at the central portion. The transition lengths increase in a direction away from an inner edge containing the air inlet so as to equalize air flow to the distal regions of the primary surface zone. |
| FILED | Thursday, August 12, 2004 |
| APPL NO | 10/917107 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Heat exchange 165/166 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147071 | Gering et al. |
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| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Kevin L. Gering (Idaho Falls, Idaho); Daryl R. Haefner (Idaho Falls, Idaho) |
| ABSTRACT | A thermal management system for a vehicle includes a heat exchanger having a thermal energy storage material provided therein, a first coolant loop thermally coupled to an electrochemical storage device located within the first coolant loop and to the heat exchanger, and a second coolant loop thermally coupled to the heat exchanger. The first and second coolant loops are configured to carry distinct thermal energy transfer media. The thermal management system also includes an interface configured to facilitate transfer of heat generated by an internal combustion engine to the heat exchanger via the second coolant loop in order to selectively deliver the heat to the electrochemical storage device. Thermal management methods are also provided. |
| FILED | Wednesday, February 04, 2004 |
| APPL NO | 10/772762 |
| ART UNIT | 3618 — Fluid Handling and Dispensing |
| CURRENT CPC | Motor vehicles 180/65.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147205 | Fischer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Gary J. Fischer (Sandia Park, New Mexico); Barry L. Spletzer (Albuquerque, New Mexico) |
| ABSTRACT | A low energy high pressure screw valve having a valve body having an upper portion and a lower portion, said lower portion of said valve body defining an inlet flow passage and an outlet flow passage traversing said valve body to a valve seat, said upper portion of said valve body defining a cavity at said valve seat, a diaphragm restricting flow between said upper portion of said valve body and said lower portion, said diaphragm capable of engaging said valve seat to restrict fluid communication between said inlet passage and said outlet passage, a plunger within said cavity supporting said diaphragm, said plunger being capable of engaging said diaphragm with said valve seat at said inlet and outlet fluid passages, said plunger being in point contact with a drive screw having threads engaged with opposing threads within said upper portion of said valve body such engagement allowing motion of said drive screw within said valve body. |
| FILED | Wednesday, June 16, 2004 |
| APPL NO | 10/870755 |
| ART UNIT | 3751 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Valves and valve actuation 251/129.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147214 | Klett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | James W. Klett (Knoxville, Tennessee); David P. Stinton (Knoxville, Tennessee) |
| ABSTRACT | A method and apparatus of supplying humid air to a fuel cell is disclosed. The extremely high thermal conductivity of some graphite foams lends itself to enhance significantly the ability to humidify supply air for a fuel cell. By utilizing a high conductivity pitch-derived graphite foam, thermal conductivity being as high as 187 W/m·K, the heat from the heat source is more efficiently transferred to the water for evaporation, thus the system does not cool significantly due to the evaporation of the water and, consequently, the air reaches a higher humidity ratio. |
| FILED | Friday, March 14, 2003 |
| APPL NO | 10/389379 |
| ART UNIT | 1754 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Gas and liquid contact apparatus 261/108 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147722 | Klebanoff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | EUV LLC (Santa Clara, California) |
| INVENTOR(S) | Leonard E. Klebanoff (Dublin, California); Philip Grunow (Livermore, California); Samuel Graham, Jr. (Dublin, California) |
| ABSTRACT | Activated gaseous species generated adjacent a carbon contaminated surface affords in-situ cleaning. A device for removing carbon contamination from a surface of the substrate includes (a) a housing defining a vacuum chamber in which the substrate is located; (b) a source of gaseous species; and (c) a source of electrons that are emitted to activate the gaseous species into activated gaseous species. The source of electrons preferably includes (i) a filament made of a material that generates thermionic electron emissions; (ii) a source of energy that is connected to the filament; and (iii) an electrode to which the emitted electrons are attracted. The device is particularly suited for photolithography systems with optic surfaces, e.g., mirrors, that are otherwise inaccessible unless the system is dismantled. A method of removing carbon contaminants from a substrate surface that is housed within a vacuum chamber is also disclosed. The method employs activated gaseous species that react with the carbon contaminants to form carbon containing gaseous byproducts. |
| FILED | Monday, May 24, 2004 |
| APPL NO | 10/852545 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Cleaning and liquid contact with solids 134/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147779 | Phifer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Westinghouse Savannah River Company (Aiken, South Carolina) |
| INVENTOR(S) | Mark A. Phifer (N. Augusta, South Carolina); Frank C. Sappington (Dahlonega, Georgia); Margaret R. Millings (N. Augusta, South Carolina); Charles E. Turick (Aiken, South Carolina); Pamela C. McKinsey (Aiken, South Carolina) |
| ABSTRACT | A bioremediation system using inorganic oxide-reducing microbial consortia for the treatment of, inter alia coal mine and coal yard runoff uses a containment vessel for contaminated water and a second, floating phase for nutrients. Biodegradable oils are preferred nutrients. |
| FILED | Tuesday, November 29, 2005 |
| APPL NO | 11/288713 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Liquid purification or separation 210/610 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147823 | Loewen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Eric P. Loewen (Idaho Falls, Idaho) |
| ABSTRACT | A method for cooling a heat source, a method for preventing chemical interaction between a vessel and a cooling composition therein, and a cooling system. The method for cooling employs a containment vessel with an oxidizable interior wall. The interior wall is oxidized to form an oxide barrier layer thereon, the cooling composition is monitored for excess oxidizing agent, and a reducing agent is provided to eliminate excess oxidation. The method for preventing chemical interaction between a vessel and a cooling composition involves introducing a sufficient quantity of a reactant which is reactive with the vessel in order to produce a barrier layer therein that is non-reactive with the cooling composition. The cooling system includes a containment vessel with oxidizing agent and reducing agent delivery conveyances and a monitor of oxidation and reduction states so that proper maintenance of a vessel wall oxidation layer occurs. |
| FILED | Monday, April 15, 2002 |
| APPL NO | 10/123391 |
| ART UNIT | 1744 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/7 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147838 | Hoffman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Timothy J. Hoffman (Columbia, Missouri); Wynn A. Volkert (Columbia, Missouri); Ning Li (Baltimore, Maryland); Gary Sieckman (Ashland, Missouri); Chrys-Ann Higginbotham (Columbia, Missouri) |
| ABSTRACT | A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor. |
| FILED | Wednesday, December 29, 2004 |
| APPL NO | 11/025636 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147953 | Haltiner, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Delphi Technologies, Inc. (Troy, Michigan) |
| INVENTOR(S) | Karl J. Haltiner, Jr. (Fairport, New York); Subhasish Mukerjee (Rochester, New York); Diane M. England (Bloomfield, New York) |
| ABSTRACT | A fuel cell assembly comprising a plurality of individual fuel cells, especially a solid-oxide fuel cell assembly. The cells are organized into a plurality of stacks, preferably two stacks, disposed side-by-side rather than end-to-end as in a prior art monolithic single stack. This arrangement makes the assembly compact physically, which can be highly desirable in some fuel cell applications. The stacks are connected conventionally in series electrically but are supplied with air and fuel in parallel to shorten the distribution manifolds and improve uniformity of distribution and exhaust among all the cells. |
| FILED | Monday, June 24, 2002 |
| APPL NO | 10/178282 |
| ART UNIT | 1746 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/32 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147966 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Zhifeng Ren (Newton, Massachusetts); Jian Wen (Newton, Massachusetts); Jinghua Chen (Chestnut Hill, Massachusetts); Zhongping Huang (Belmont, Massachusetts); Dezhi Wang (Wellesley, Massachusetts) |
| ABSTRACT | The present invention provides conductive carbon nanotube (CNT) electrode materials comprising aligned CNT substrates coated with an electrically conducting polymer, and the fabrication of electrodes for use in high performance electrical energy storage devices. In particular, the present invention provides conductive CNTs electrode material whose electrical properties render them especially suitable for use in high efficiency rechargeable batteries. The present invention also provides methods for obtaining surface modified conductive CNT electrode materials comprising an array of individual linear, aligned CNTs having a uniform surface coating of an electrically conductive polymer such as polypyrrole, and their use in electrical energy storage devices. |
| FILED | Wednesday, November 27, 2002 |
| APPL NO | 10/305804 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/209 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148040 | Meagher et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | University of Georgia Research Foundation, Inc. (Athens, Georgia); Abeome Corporation (Athens, Georgia) |
| INVENTOR(S) | Richard B. Meagher (Athens, Georgia); Vince Laterza (Decatur, Georgia) |
| ABSTRACT | The present invention relates to genetically altered hybridomas, myelomas and B cells. The invention also relates to utilizing genetically altered hybridomas, myelomas and B cells in methods of making monoclonal antibodies. The present invention also provides populations of hybridomas and B cells that can be utilized to make a monoclonal antibody of interest. |
| FILED | Wednesday, February 20, 2002 |
| APPL NO | 10/079130 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/70.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148180 | Coronado et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Paul R. Coronado (Livermore, California); Sabre J. Coleman (Oakland, California); John G. Reynolds (San Ramon, California) |
| ABSTRACT | Functionalized hydrophobic aerogel/solid support structure composites have been developed to remove metals and organic compounds from aqueous and vapor media. The targeted metals and organics are removed by passing the aqueous or vapor phase through the composite which can be in molded, granular, or powder form. The composites adsorb the metals and the organics leaving a purified aqueous or vapor stream. The species-specific adsorption occurs through specific functionalization of the aerogels tailored towards specific metals and/or organics. After adsorption, the composites can be disposed of or the targeted metals and/or organics can be reclaimed or removed and the composites recycled. |
| FILED | Thursday, March 04, 2004 |
| APPL NO | 10/794853 |
| ART UNIT | 1754 — Semiconductors/Memory |
| CURRENT CPC | Catalyst, solid sorbent, or support therefor: Product or process of making 52/214 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148389 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Ralph T. Yang (Ann Arbor, Michigan); Frances H. Yang (Ann Arbor, Michigan); Akira Takahashi (Yoko-Machi, Japan); Arturo J. Hermandez-Maldonado (Ann Arbor, Michigan) |
| ABSTRACT | A method for removing thiophene and thiophene compounds from liquid fuel includes contacting the liquid fuel with an adsorbent which preferentially adsorbs the thiophene and thiophene compounds. The adsorption takes place at a selected temperature and pressure, thereby producing a non-adsorbed component and a thiophene/thiophene compound-rich adsorbed component. The adsorbent includes either a metal or a metal ion that is adapted to form π-complexation bonds with the thiophene and/or thiophene compounds, and the preferential adsorption occurs by π-complexation. A further method includes selective removal of aromatic compounds from a mixture of aromatic and aliphatic compounds. |
| FILED | Wednesday, September 04, 2002 |
| APPL NO | 10/234681 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry of hydrocarbon compounds 585/250 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148436 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Robb M. Lee (Albuquerque, New Mexico); Randy J. Shul (Albuquerque, New Mexico); Marc A. Polosky (Albuquerque, New Mexico); Darren A. Hoke (Albuquerque, New Mexico); George E. Vernon (Rio Rancho, New Mexico) |
| ABSTRACT | An acceleration-sensing apparatus is disclosed which includes a moveable shuttle (i.e. a suspended mass) and a latch for capturing and holding the shuttle when an acceleration event is sensed above a predetermined threshold level. The acceleration-sensing apparatus provides a switch closure upon sensing the acceleration event and remains latched in place thereafter. Examples of the acceleration-sensing apparatus are provided which are responsive to an acceleration component in a single direction (i.e. a single-sided device) or to two oppositely-directed acceleration components (i.e. a dual-sided device). A two-stage acceleration-sensing apparatus is also disclosed which can sense two acceleration events separated in time. The acceleration-sensing apparatus of the present invention has applications, for example, in an automotive airbag deployment system. |
| FILED | Thursday, August 14, 2003 |
| APPL NO | 10/641860 |
| ART UNIT | 2832 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Electricity: Circuit makers and breakers 2/61.480 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148460 | Moses et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | William W. Moses (Berkeley, California); Eric Beuville (Santa Barbara, California); Marzio Pedrali-Noy (San Diego, California) |
| ABSTRACT | An integrated circuit which provides multi-channel detector readout from a detector array. The circuit receives multiple signals from the elements of a detector array and compares the sampled amplitudes of these signals against a noise-floor threshold and against one another. A digital signal is generated which corresponds to the location of the highest of these signal amplitudes which exceeds the noise floor threshold. The digital signal is received by a multiplexing circuit which outputs an analog signal corresponding the highest of the input signal amplitudes. In addition a digital control section provides for programmatic control of the multiplexer circuit, amplifier gain, amplifier reset, masking selection, and test circuit functionality on each input thereof. |
| FILED | Thursday, March 25, 2004 |
| APPL NO | 10/809931 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/214.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148474 | Tang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Keqi Tang (Richland, Washington); Alexandre A. Shvartsburg (Richland, Washington); Richard D. Smith (Richland, Washington) |
| ABSTRACT | The present invention relates to a device for separation and characterization of gas-phase ions. The device incorporates an ion source, a field asymmetric waveform ion mobility spectrometry (FAIMS) analyzer, an ion mobility spectrometry (IMS) drift tube, and an ion detector. In one aspect of the invention, FAIMS operating voltages are electrically floated on top of the IMS drift voltage. In the other aspect, the FAIMS/IMS interface is implemented employing an electrodynamic ion funnel, including in particular an hourglass ion funnel. The present invention improves the efficiency (peak capacity) and sensitivity of gas-phase separations; the online FAIMS/IMS coupling creates a fundamentally novel two-dimensional gas-phase separation technology with high peak capacity, specificity, and exceptional throughput. |
| FILED | Monday, April 11, 2005 |
| APPL NO | 11/103984 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/287 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148484 | Craig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | William W. Craig (Pittsburg, California); Simon E. Labov (Berkeley, California) |
| ABSTRACT | A network of radiation detection instruments, each having a small solid state radiation sensor module integrated into a cellular phone for providing radiation detection data and analysis directly to a user. The sensor module includes a solid-state crystal bonded to an ASIC readout providing a low cost, low power, light weight compact instrument to detect and measure radiation energies in the local ambient radiation field. In particular, the photon energy, time of event, and location of the detection instrument at the time of detection is recorded for real time transmission to a central data collection/analysis system. The collected data from the entire network of radiation detection instruments are combined by intelligent correlation/analysis algorithms which map the background radiation and detect, identify and track radiation anomalies in the region. |
| FILED | Wednesday, July 30, 2003 |
| APPL NO | 10/632169 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/370.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148603 | Garcia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Ernest J. Garcia (Albuquerque, New Mexico); Marc A. Polosky (Tijeras, New Mexico); Gerard E. Sleefe (Cedar Crest, New Mexico) |
| ABSTRACT | A microelectromechanical (MEM) apparatus is disclosed which includes a platform that can be electrostatically tilted from being parallel to a substrate on which the platform to being tilted at an angle of 1–20 degrees with respect to the substrate. Once the platform has been tilted to a maximum angle of tilt, the platform can be locked in position using an electrostatically-operable latching mechanism which engages a tab protruding below the platform. The platform has a light-reflective upper surface which can be optionally coated to provide an enhanced reflectivity and form a micromirror. An array of such micromirrors can be formed on a common substrate for applications including optical switching (e.g. for fiber optic communications), optical information processing, image projection displays or non-volatile optical memories. |
| FILED | Wednesday, November 27, 2002 |
| APPL NO | 10/307216 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/309 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148777 | Chell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Astronautics Corporation of America (Milwaukee, Wisconsin) |
| INVENTOR(S) | Jeremy Chell (Madison, Wisconsin); Carl B. Zimm (Madison, Wisconsin) |
| ABSTRACT | A permanent magnet assembly is disclosed that is adapted to provide a magnetic field across an arc-shaped gap. Such a permanent magnet assembly can be used, for example, to provide a time-varying magnetic field to an annular region for use in a magnetic refrigerator. |
| FILED | Thursday, February 03, 2005 |
| APPL NO | 11/050109 |
| ART UNIT | 2832 — Semiconductors/Memory |
| CURRENT CPC | Electricity: Magnetically operated switches, magnets, and electromagnets 335/306 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148778 | Humphries et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | David E. Humphries (El Cerrito, California); Martin J. Pollard (El Cerrito, California); Christopher J. Elkin (San Ramon, California) |
| ABSTRACT | The present disclosure provides a high performance hybrid magnetic structure made from a combination of permanent magnets and ferromagnetic pole materials which are assembled in a predetermined array. The hybrid magnetic structure provides for separation and other biotechnology applications involving holding, manipulation, or separation of magnetic or magnetizable molecular structures and targets. Also disclosed are: a method of assembling the hybrid magnetic plates, a high throughput protocol featuring the hybrid magnetic structure, and other embodiments of the ferromagnetic pole shape, attachment and adapter interfaces for adapting the use of the hybrid magnetic structure for use with liquid handling and other robots for use in high throughput processes. |
| FILED | Tuesday, October 11, 2005 |
| APPL NO | 11/248934 |
| ART UNIT | 2832 — Semiconductors/Memory |
| CURRENT CPC | Electricity: Magnetically operated switches, magnets, and electromagnets 335/306 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148836 | Romero et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Carlos E. Romero (Livermore, California); James E. Zumstein (Livermore, California); John T. Chang (Danville, California); Richard R. Leach, Jr. (Castro Valley, California) |
| ABSTRACT | An obstacle penetrating dynamic radar imaging system for the detection, tracking, and imaging of an individual, animal, or object comprising a multiplicity of low power ultra wideband radar units that produce a set of return radar signals from the individual, animal, or object, and a processing system for said set of return radar signals for detection, tracking, and imaging of the individual, animal, or object. The system provides a radar video system for detecting and tracking an individual, animal, or object by producing a set of return radar signals from the individual, animal, or object with a multiplicity of low power ultra wideband radar units, and processing said set of return radar signals for detecting and tracking of the individual, animal, or object. |
| FILED | Monday, February 28, 2005 |
| APPL NO | 11/069329 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148969 | Thomas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | UT-Battelle LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Clarence E. Thomas (Knoxville, Tennessee); Gregory R. Hanson (Clinton, Tennessee) |
| ABSTRACT | An apparatus operable to record a spatially low-frequency heterodyne hologram including spatially heterodyne fringes for Fourier analysis includes: a laser; a beamsplitter optically coupled to the laser; an object optically coupled to the beamsplitter; a focusing lens optically coupled to both the beamsplitter and the object; a digital recorder optically coupled to the focusing lens; and a computer that performs a Fourier transform, applies a digital filter, and performs an inverse Fourier transform. A reference beam and an object beam are focused by the focusing lens at a focal plane of the digital recorder to form a spatially low-frequency heterodyne hologram including spatially heterodyne fringes for Fourier analysis which is recorded by the digital recorder, and the computer transforms the recorded spatially low-frequency heterodyne hologram including spatially heterodyne fringes and shifts axes in Fourier space to sit on top of a heterodyne carrier frequency defined by an angle between the reference beam and the object beam and cuts off signals around an original origin before performing the inverse Fourier transform. |
| FILED | Monday, January 09, 2006 |
| APPL NO | 11/327851 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/484 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148974 | Schmitt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Randal L. Schmitt (Tijeras, New Mexico); Susan Fae Ann Bender (Tijeras, New Mexico); Philip J. Rodacy (Albuquerque, New Mexico); Philip J. Hargis, Jr. (Albuquerque, New Mexico); Mark S. Johnson (Albuquerque, New Mexico) |
| ABSTRACT | A method for tracking the movement and position of mobile agents using light detection and ranging (LIDAR) as a stand-off optical detection technique. The positions of the agents are tracked by analyzing the time-history of a series of optical measurements made over the field of view of the optical system. This provides a (time+3-D) or (time+2-D) mapping of the location of the mobile agents. Repeated pulses of a laser beam impinge on a mobile agent, such as a bee, and are backscattered from the agent into a LIDAR detection system. Alternatively, the incident laser pulses excite fluorescence or phosphorescence from the agent, which is detected using a LIDAR system. Analysis of the spatial location of signals from the agents produced by repeated pulses generates a multidimensional map of agent location. |
| FILED | Tuesday, January 13, 2004 |
| APPL NO | 10/757697 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/622 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149472 | Reagor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | David Reagor (Los Alamos, New Mexico); Jose Vasquez-Dominguez (Los Alamos, New Mexico) |
| ABSTRACT | A through-the-earth communication system that includes a digital signal input device; a transmitter operating at a predetermined frequency sufficiently low to effectively penetrate useful distances through-the earth; a data compression circuit that is connected to an encoding processor; an amplifier that receives encoded output from the encoding processor for amplifying the output and transmitting the data to an antenna; and a receiver with an antenna, a band pass filter, a decoding processor, and a data decompressor. |
| FILED | Tuesday, February 28, 2006 |
| APPL NO | 11/364396 |
| ART UNIT | 2617 — Optics |
| CURRENT CPC | Telecommunications 455/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149567 | Demos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Stavros Demos (Livermore, California); Michael C. Staggs (Tracy, California) |
| ABSTRACT | Near infrared imaging using elastic light scattering and tissue autofluorescence are explored for medical applications. The approach involves imaging using cross-polarized elastic light scattering and tissue autofluorescence in the Near Infra-Red (NIR) coupled with image processing and inter-image operations to differentiate human tissue components. |
| FILED | Friday, December 02, 2005 |
| APPL NO | 11/293590 |
| ART UNIT | 3742 — Optics |
| CURRENT CPC | Surgery 6/473 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 07147687 | Mirkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | Nanosphere, Inc. (Northbrook, Illinois) |
| INVENTOR(S) | Chad A. Mirkin (Wilmette, Illinois); Yun-Wei Cao (Evanston, Illinois); Rongchao Jin (Evanston, Illinois) |
| ABSTRACT | The present invention relates composite core/shell nanoparticles and a two-step method for their preparation. The present invention further relates to biomolecule-core/shell nanoparticle conjugates and methods for their preparation. The invention also relates to methods of detection of biomolecules comprising the biomolecule-core/shell nanoparticle conjugates. |
| FILED | Wednesday, May 22, 2002 |
| APPL NO | 10/153483 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specialized metallurgical processes, compositions for use therein, consolidated metal powder compositions, and loose metal particulate mixtures 075/343 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147966 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Zhifeng Ren (Newton, Massachusetts); Jian Wen (Newton, Massachusetts); Jinghua Chen (Chestnut Hill, Massachusetts); Zhongping Huang (Belmont, Massachusetts); Dezhi Wang (Wellesley, Massachusetts) |
| ABSTRACT | The present invention provides conductive carbon nanotube (CNT) electrode materials comprising aligned CNT substrates coated with an electrically conducting polymer, and the fabrication of electrodes for use in high performance electrical energy storage devices. In particular, the present invention provides conductive CNTs electrode material whose electrical properties render them especially suitable for use in high efficiency rechargeable batteries. The present invention also provides methods for obtaining surface modified conductive CNT electrode materials comprising an array of individual linear, aligned CNTs having a uniform surface coating of an electrically conductive polymer such as polypyrrole, and their use in electrical energy storage devices. |
| FILED | Wednesday, November 27, 2002 |
| APPL NO | 10/305804 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/209 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148017 | Craighead et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | Harold G. Craighead (Ithaca, New York); Bojan Ilic (Ithaca, New York); David Alan Czaplewski (Ithaca, New York); Robert H. Hall (Clarksville, Maryland) |
| ABSTRACT | A system and method for detecting mass based on a frequency differential of a resonating micromachined structure, such as a cantilever beam. A high aspect ratio cantilever beam is coated with an immobilized binding partner that couples to a predetermined cell or molecule. A first resonant frequency is determined for the cantilever having the immobilized binding partner. Upon exposure of the cantilever to a solution that binds with the binding partner, the mass of the cantilever beam increases. A second resonant frequency is determined and the differential resonant frequency provides the basis for detecting the target cell or molecule. The cantilever may be driven externally or by ambient noise. The frequency response of the beam can be determined optically using reflected light and two photodetectors or by interference using a single photodetector. |
| FILED | Tuesday, November 14, 2000 |
| APPL NO | 09/712795 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148356 | Smith, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Milton R. Smith, III (East Lansing, Michigan); Robert E. Maleczka (Dewitt, Michigan) |
| ABSTRACT | A process for producing organic substituted aromatic or heteroaromatic compounds including biaryl and biheteroaryl compounds in a two-step reaction. In the first step, the aromatic or heteroaromatic compound is borylated in a reaction comprising a borane or diborane reagent (any boron reagent where the boron reagent contains a B—H, B—B or B—Si bond) and an iridium or rhodium catalytic complex. In the second step, a metal catalyst catalyzes the formation of the organic substituted aromatic or heteroaromatic compound from the borylated compound and an electrophile such as an aryl or organic halide, triflate (OSO2CF3), or nonaflate (OSO2C4F9). The steps in the process can be performed in a single reaction vessel or in separate reaction vessels. The present invention also provides a process for synthesis of complex polyphenylenes starting from halogenated aromatic compounds. |
| FILED | Monday, March 14, 2005 |
| APPL NO | 11/079672 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 546/250 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148389 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Ralph T. Yang (Ann Arbor, Michigan); Frances H. Yang (Ann Arbor, Michigan); Akira Takahashi (Yoko-Machi, Japan); Arturo J. Hermandez-Maldonado (Ann Arbor, Michigan) |
| ABSTRACT | A method for removing thiophene and thiophene compounds from liquid fuel includes contacting the liquid fuel with an adsorbent which preferentially adsorbs the thiophene and thiophene compounds. The adsorption takes place at a selected temperature and pressure, thereby producing a non-adsorbed component and a thiophene/thiophene compound-rich adsorbed component. The adsorbent includes either a metal or a metal ion that is adapted to form π-complexation bonds with the thiophene and/or thiophene compounds, and the preferential adsorption occurs by π-complexation. A further method includes selective removal of aromatic compounds from a mixture of aromatic and aliphatic compounds. |
| FILED | Wednesday, September 04, 2002 |
| APPL NO | 10/234681 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry of hydrocarbon compounds 585/250 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149262 | Nayar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Shree K. Nayar (New York, New York); Srinivasa G. Narasimhan (New York, New York) |
| ABSTRACT | A resolution enhancement algorithm is trained on sample images to obtain a polynomial model mapping of low resolution image data to high resolution image data. The polynomial model mapping is applied to other low resolution images to obtain corresponding higher resolution images. The mapping provides resolution enhancement which is superior to that of conventional image data interpolation techniques. |
| FILED | Friday, July 06, 2001 |
| APPL NO | 10/312529 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Pulse or digital communications 375/341 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 07147894 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Otto Z. Zhou (Chapel Hill, North Carolina); Hideo Shimoda (Chapel Hill, North Carolina); Soojin Oh (Chapel Hill, North Carolina) |
| ABSTRACT | A method for the self assembly of a macroscopic structure with a pre-formed nano object is provided. The method includes processing a nano object to a desired aspect ratio and chemical functionality and mixing the processed nano object with a solvent to form a suspension. Upon formation of the suspension, a substrate is inserted into the suspension. By either evaporation of the solvent, changing the pH value of the suspension, or changing the temperature of the suspension, the nano objects within the suspension deposit onto the substrate in an orientational order. In addition, a seed crystal may be used in place of the substrate thereby forming single-crystals and free-standing membranes of the nano-objects. |
| FILED | Monday, March 25, 2002 |
| APPL NO | 10/103803 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Coating processes 427/256 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07147958 | Prakash et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Surya Prakash (Hacienda Hts., California); Sekharipuram R. Narayanan (Arcadia, California); Anthony Atti (Pasadena, California); George Olah (Beverly Hills, California); Marshall C. Smart (Studio City, California) |
| ABSTRACT | A catalyst ink for a fuel cell including a catalytic material and poly(vinylidene fluoride). The ink may be applied to a substrate to form an electrode, or bonded with other electrode layers to form a membrane electrode assembly (MEA). |
| FILED | Tuesday, July 24, 2001 |
| APPL NO | 09/912804 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/42 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148417 | Landis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Geoffrey A. Landis (Berea, Ohio) |
| ABSTRACT | A two-junction solar cell has a bottom solar cell junction of crystalline silicon, and a top solar cell junction of gallium phosphide. A three (or more) junction solar cell has bottom solar cell junctions of silicon, and a top solar cell junction of gallium phosphide. The resulting solar cells exhibit improved extended temperature operation. |
| FILED | Monday, March 31, 2003 |
| APPL NO | 10/403714 |
| ART UNIT | 1753 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Batteries: Thermoelectric and photoelectric 136/262 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07149014 | Chao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Tien-Hsin Chao (Valencia, California); Jay C. Hanan (Monrovia, California); George F. Reyes (Fontana, California); Hanying Zhou (Arcadia, California) |
| ABSTRACT | A method, apparatus, and system provide the ability for storing holograms at high speed. A single laser diode emits a collimated laser beam to both write to and read from a photorefractice crystal. One or more liquid crystal beam steering spatial light modulators (BSSLMs) or Micro-Electro-Mechanical Systems (MEMS) mirrors steer a reference beam, split from the collimated laser beam, at high speed to the photorefractive crystal. |
| FILED | Thursday, April 15, 2004 |
| APPL NO | 10/824722 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/22 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 07148203 | Hackett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Perry B. Hackett (Shoreview, Minnesota); Zoltan Ivics (Berlin, Germany); Zsuzsanna Izsvak (Berlin, Germany) |
| ABSTRACT | This invention relates to a system for introducing nucleic acid into the DNA of a cell. The system includes the use of a member of the SB family of transposases (SB) or nucleic acid encoding the transposase and a nucleic acid fragment that includes a nucleic acid sequence with flanking inverted repeats. The transposase recognizes at least a portion of an inverted repeats and incorporates the nucleic acid sequence into the DNA. Methods for use of this system are discussed. |
| FILED | Wednesday, October 02, 2002 |
| APPL NO | 10/263159 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 07148397 | Osumi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Teruko Osumi (Blacksburg, Virginia); William R. Belknap (Albany, California); David R. Rockhold (El Cerrito, California); Mary M. Maccree (Encinitas, California); Kent F. McCue (El Cerrito, California); Kenneth L. Deahl (Silver Spring, Maryland) |
| ABSTRACT | A Solanum bulbocastanum gene has been cloned from a late blight-resistance locus and its sequence provided, together with the sequence of the encoded protein. DNA encoding the resistance protein has been introduced into potato plants and confers resistance to Phytophthora infestans, the causal agent of late blight. The resistance protein is in the class of Nucleotide Binding Site-Leucine-Rich Repeat Proteins (NBS-LRRP), and the gene in S. bulbocastanum is flanked by related NBS-LRRP gene sequences. |
| FILED | Wednesday, August 20, 2003 |
| APPL NO | 10/647268 |
| ART UNIT | 1638 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/279 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 07147906 | Herrmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Eugene David Herrmann (Clifton Park, New York); James Anthony Cella (Clifton Park, New York); John Bradford Reitz (Clifton Park, New York); Racid Kerboua (Schenectady, New York); Irene Dris (Clifton Park, New York) |
| ABSTRACT | In one aspect the present invention provides a storage medium for data, the storage medium comprising: a) a substrate, a physical portion of which comprises at least one polyimide, and b) at least one data layer on the substrate. The substrate comprising a polyimide exhibits low axial displacement and beneficial damping characteristics. |
| FILED | Tuesday, June 24, 2003 |
| APPL NO | 10/603497 |
| ART UNIT | 1711 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Stock material or miscellaneous articles 428/64.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 07147838 | Hoffman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | |
| ASSIGNEE(S) | Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Timothy J. Hoffman (Columbia, Missouri); Wynn A. Volkert (Columbia, Missouri); Ning Li (Baltimore, Maryland); Gary Sieckman (Ashland, Missouri); Chrys-Ann Higginbotham (Columbia, Missouri) |
| ABSTRACT | A compound for use as a therapeutic or diagnostic radiopharmaceutical includes a group capable of complexing a medically useful metal attached to a moiety which is capable of binding to a gastrin releasing peptide receptor. A method for treating a subject having a neoplastic disease includes administering to the subject an effective amount of a radiopharmaceutical having a metal chelated with a chelating group attached to a moiety capable of binding to a gastrin releasing peptide receptor expressed on tumor cells with subsequent internalization inside of the cell. A method of forming a therapeutic or diagnostic compound includes reacting a metal synthon with a chelating group covalently linked with a moiety capable of binding a gastrin releasing peptide receptor. |
| FILED | Wednesday, December 29, 2004 |
| APPL NO | 11/025636 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 07148033 | Brenner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the U. S. Environmental Protection Agency (Washington, District of Columbia) |
| INVENTOR(S) | Kristen P. Brenner (Cincinnati, Ohio); Clifford C. Rankin (Dayton, Ohio); Yvette R. Roybal-McKenna (Gilbert, Arizona); Alfred P. Dufour (Cincinnati, Ohio) |
| ABSTRACT | An improved method for detection of total coliforms and E. coli comprising a broth containing an ingredient that will suppress growth of non-coliform gram negative bacteria, and at least one chromogen or fluorogen has been used effectively and is cost effective. Preferred methods include use of filter and/or plates containing the growth-promoting ingredients and the indicators. |
| FILED | Monday, November 17, 2003 |
| APPL NO | 10/713113 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/34 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 07147625 | Sarangapani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | ICET, Inc. (Norwood, Massachusetts) |
| INVENTOR(S) | Shantha Sarangapani (Walpole, Massachusetts); Fletcher Tifft Longley (Westwood, Massachusetts) |
| ABSTRACT | An accessory is connected between a leg bag and a urinary catheter to prevent microorganisms migrating from the leg bag up through the catheter. The accessory has a sleeve, connectors to connect the sleeve to the leg bag and to the urinary catheter, a filter positioned within the sleeve that can be coated with an antimicrobial composition, and a valve to prevent fluid from moving from the leg bag to the catheter. The antimicrobial coated sleeve can be used with or with out the filter. The filter is made by compounding a polymeric resin powder with an antimicrobial composition. |
| FILED | Tuesday, July 01, 2003 |
| APPL NO | 10/611301 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Surgery 64/317 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 07148405 | Mok et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | State of Oregon Acting by and through the State Board of Higher Education on behalf of Oregon State University (Corvallis, Oregon); Pioneer Hi-Bred International, Inc. (Johnston, Iowa) |
| INVENTOR(S) | David W. S. Mok (Corvallis, Oregon); Machteld C. Mok (Corvallis, Oregon); Ruth C. Martin (Corvallis, Oregon); Jeffrey E. Habben (Urbandale, Iowa) |
| ABSTRACT | Isolated nucleic acids encoding cis-zeatin O-glucosyltransferase are disclosed. These nucleic acid molecules are useful, among other things, to produce transgenic plants having modified cis-zeatin O-glucosyltransferase activity and/or modified growth and developmental patterns. |
| FILED | Tuesday, June 05, 2001 |
| APPL NO | 10/275782 |
| ART UNIT | 1638 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Multicellular living organisms and unmodified parts thereof and related processes 8/298 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 07147088 | Reid et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | |
| ASSIGNEE(S) | |
| INVENTOR(S) | John D. Reid (Lincoln, Nebraska); John R. Rohde (Lincoln, Nebraska); Dean L. Sicking (Houston, Texas) |
| ABSTRACT | A single-sided crash attenuation cushion system having an impact head and three stage energy absorption mechanism. The energy absorbing mechanism has a mandrel for deforming thin-walled tubes in a controlled collapse to absorb impact forces from a colliding vehicle. The third stage of the absorption mechanism includes an additional deformable compressible tube between the fixed-object hazard and the thin walled tubes. |
| FILED | Thursday, June 23, 2005 |
| APPL NO | 11/158984 |
| ART UNIT | 3683 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation |
| CURRENT CPC | Brakes 188/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 12, 2006.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2006/fedinvent-patents-20061212.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page