FedInvent™ Patents

Patent Details for Tuesday, July 10, 2012 

This page was updated on Monday, March 27, 2023 at 03:22 AM GMT

Department of Defense (DOD) 

US 08215112 Owens et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) TIAX LLC (Lexington, Massachusetts)
INVENTOR(S) Kingston Owens (Bedford, New Hampshire);  John T. Dieckmann (Belmont, Massachusetts);  Kenan Sahin (Boston, Massachusetts)
ABSTRACT A free piston Stirling engine, comprising a power piston fitted into a cylinder further includes: a support structure carrying moving magnets for a linear alternator; and a passive structure that at normal operating power and frequency produces a restoring force on the piston in the absence of contact with the cylinder. In one variation, the passive structure further comprises a mass suspended within the piston from at least one spring, such that the mass oscillates under influence of movement of the piston at normal operating power and frequency so as to produce the restoring force. In another variation, the passive structure further comprises: a magnet disposed outside the cylinder at a position and in an orientation to produce a field that opposes a field of a moving magnet carried by the support structure when the piston moves toward the magnet.
FILED Wednesday, November 26, 2008
APPL NO 12/324797
ART UNIT 3748 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Power plants
060/520
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215115 Adair et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Hamilton Sundstrand Corporation (Windsor Locks, Connecticut)
INVENTOR(S) David Ronald Adair (Valley Center, California);  Walter Ernest Ainslie (Ramona, California);  Gordon F. Jewess (San Diego, California);  Anthony C. Jones (San Diego, California);  Eric J. Alexander (San Diego, California)
ABSTRACT A gas turbine engine sealing arrangement which includes a combustor liner establishing a combustion area and a turbine nozzle configured to receive a portion of a combustor liner. A sealing ring arrangement is configured to seal with the turbine nozzle to control fluid flow from the combustion area and reduce leakage.
FILED Monday, September 28, 2009
APPL NO 12/568615
ART UNIT 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Power plants
060/752
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215224 Tortorici, Jr. et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Richard W. Tortorici, Jr. (Schenectady, New York);  Ronald Gast (Cohoes, New York);  Edward Hyland (Waterford, New York);  Richard W. Tortorici, III (Cohoes, New York)
ABSTRACT A recoil brake includes a control rod disposed in a central opening in a piston and cylinder assembly. A fluid passage leads from the piston to the control rod. A long stroke body is fixed to the piston and defines a long stroke orifice around the control rod. A short stroke body is removably disposed in the long stroke orifice. The short stroke body defines a short stroke orifice around the control rod, the short stroke orifice being smaller than the long stroke orifice. The recoil brake may be used with a 120 mm gun.
FILED Friday, August 28, 2009
APPL NO 12/549794
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/43.10
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215225 Zangrando et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Roy Zangrando (Boonton, New Jersey);  William Burgermeister (Freehold, New Jersey)
ABSTRACT An air, land, or sea vehicle may include a gun and a rotatable turret ring. An autoloader may be disposed in a basket fixed to the turret ring. The autoloader may include a turntable that rotates independently of the turret ring. An elevator having a track may rotate with the turntable. A carriage may be linearly translatable on the track of the elevator in directions toward and away from the plane of the turntable. A transfer device may be rotatably fixed to a pivot of the carriage. The transfer device may include a rail and a gripper that is linearly translatable on the rail.
FILED Thursday, June 03, 2010
APPL NO 12/792829
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ordnance
089/46
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215236 Bass
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jamie Bass (Elnora, Indiana)
ABSTRACT A system and method of detecting, processing, and selectively responding to radio frequency transmissions detected by at least one projectile deployed above a geographic area.
FILED Tuesday, January 11, 2011
APPL NO 13/004350
ART UNIT 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Ammunition and explosives
12/387
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US 08215314 Chan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts)
INVENTOR(S) Barbara Chan (Cambridge, Massachusetts);  Timothy Shane Johnson (Jamaica Plain, Massachusetts);  Irene E. Kochevar (Charlestown, Massachusetts);  Mark Randolph (Chelmsford, Massachusetts);  Robert W. Redmond (West Newton, Massachusetts);  Jonathan M. Winograd (Sudbury, Massachusetts)
ABSTRACT Photochemical tissue boding methods for bonding neural tissues include the application of a photosensitizer to a tissue and/or tissue graft, followed by irradiation with electromagnetic energy to produce a tissue seal. The methods are useful for tissue adhesion, such as in wound closure, tissue grafting, skin grafting, musculoskeletal tissue repair, ligament or tendon repair, neural repair, blood vessel repair and corneal repair.
FILED Tuesday, December 09, 2003
APPL NO 10/732032
ART UNIT 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Surgery
128/898
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215498 Rathbone et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Jason Rathbone (Amesbury, Massachusetts);  Michael Rotelli (Pepperell, Massachusetts);  David Tolmie (Waltham, Massachusetts)
ABSTRACT The subject invention features, in one example, a modular rack system including a plurality of legs each including an integral cable raceway and arranged to define electronic equipment bays between spaced legs, equipment mounting rails for the bays; and a cable management tray extending across the top of each bay.
FILED Wednesday, April 30, 2008
APPL NO 12/150770
ART UNIT 3637 — Static Structures, Supports and Furniture
CURRENT CPC
Supports: Racks
211/26.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215581 Kulesha
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Richard L. Kulesha (Bear, Delaware)
ABSTRACT A method and apparatus for operating a cargo ramp system. A ramp having a first end and a second end may be moved between a deployed position and an undeployed position using a movement system. The ramp may be maintained in a substantially horizontal position when the ramp is in the deployed position using a hinge system associated with the first end.
FILED Wednesday, July 08, 2009
APPL NO 12/499510
ART UNIT 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/118.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215604 Keicher
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Craig A. Keicher (Fredericksburg, Virginia)
ABSTRACT An antenna mount is provided for securing an antenna at a conex enclosure. The mount includes a box bracket having a plurality of flanges, a base plate disposable beneath the box bracket, and a tensioner plate disposable beneath the base plate. The box bracket has a top surface with an orifice to receive the antenna. The base plate is securable to the flanges by a first plurality of fasteners. The tensioner plate is securable to the base plate by a second plurality of fasteners. The box bracket forms a sheet metal plate folded to form a box with fore, aft, lateral and top sides.
FILED Tuesday, September 14, 2010
APPL NO 12/924029
ART UNIT 3632 — Static Structures, Supports and Furniture
CURRENT CPC
Supports
248/534
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215621 Koehler et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Sea Systems Command (NAVSEA)
APPLICANT(S)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) Frederick B. Koehler (Tucson, Arizona);  Ward D. Lyman (Tucson, Arizona);  Kenneth E. Schmidt (Tucson, Arizona)
ABSTRACT A spring including a wire having an elasticity by which the wire is compressible by an external force to a first position at which first and second ends thereof of are separated by a first distance and when the force is removed or an electrical current applied, the wire is extensible in response to an internal spring force to a second position at which the wire is substantially straight. A spring assembly is disclosed including a plurality of inventive wires cross-coupled with a support structure consisting of a plurality of coaxial rings. In the assembly, the wires extend parallel to an axis through a center of the rings.
FILED Thursday, March 17, 2011
APPL NO 13/050754
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Spring devices
267/182
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215878 Rozzi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Creare Incorporated (Hanover, New Hampshire)
INVENTOR(S) Jay Christopher Rozzi (Hanover, New Hampshire);  John Kendall Sanders (Hartland, Vermont);  Christian Henry Passow (Etna, New Hampshire);  Michael Phillip Day (Cornish, New Hampshire);  Everett Edgar Archibald, Jr. (Windsor, Vermont)
ABSTRACT An indirect cooling system for a rotating cutting tool uses a cryogenic coolant that is delivered to a cavity formed on the back surface of the cutting element, providing cooling near the cutting edge of the element. Because the total flow rate of the working fluid is low (less than 0.08 Liters/min/cutting edge), the fluid can be safely vented to atmosphere from the cavity, and as a result, no specialized coolant recovery or ventilation equipment is needed. The cavity may be formed with fins to enhance the heat transfer between the cutting element and the coolant, and coolant may additionally be sprayed directly onto the exterior surface of the element to cool the tool-chip interface. The indirect cooling system may be used for hard to machine metals and composites, as well as the machining of conventional materials without the use of traditional cutting fluids.
FILED Wednesday, April 22, 2009
APPL NO 12/428201
ART UNIT 3724 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Cutters, for shaping
47/11
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US 08215895 Henry et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Rolls-Royce Corporation (Indianapolis, Indiana)
INVENTOR(S) Mark S. Henry (Indianapolis, Indiana);  Daniel Kent Vetters (Indianapolis, Indiana)
ABSTRACT Embodiments of the present invention include a method and system for carrying out vapor-phase lubrication of a component, such as a bearing for example. The method and apparatus can be applied to a turbine engine. The method includes the step of directing a first stream of fluid containing atomized lubricant to the component at a first velocity. The system provides a first fluid injection system configured to perform the first step. The method also includes the step of directing a second stream of fluid at a second velocity less than the first velocity to the component. The second stream is for controlling a temperature of the component. The system provides a second fluid injection system configured to perform the second step. Both of the directing steps are carried out concurrently.
FILED Monday, March 03, 2008
APPL NO 12/041034
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/1
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215919 Jewess et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) Hamilton Sundstrand Corporation (Rockford, Illinois)
INVENTOR(S) Gordon F. Jewess (San Diego, California);  Tuan H. Nguyen (San Diego, California);  Tammy L. Lane (San Diego, California);  Reginald G. Keetley (San Diego, California)
ABSTRACT A rotor assembly for a miniature gas turbine propulsion system comprises a centrifugal compressor wheel, a turbine wheel, a shaft and a tie bolt. The centrifugal compressor wheel includes a first curved tooth coupling, and the turbine wheel includes a second curved tooth coupling interconnected with the first curved tooth coupling. The shaft extends from the centrifugal compressor wheel, and the tie bolt extends between the shaft and the turbine wheel to bring the first curved tooth coupling into compression with the second curved tooth coupling. As such, the compressor wheel and the turbine wheel are assembled and remain, over the operational envelope of the propulsion system, in a reliably robust aligned configuration.
FILED Friday, February 22, 2008
APPL NO 12/070968
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/244.R00
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215925 Garland et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Delphi Technologies Holding S.arl (Troy, Michigan)
INVENTOR(S) Paul Francis Garland (Gillingham, United Kingdom);  Andrew D Brown (Faversham, United Kingdom)
ABSTRACT A tappet suitable for use with a fluid pump includes a side wall portion and an end face which define an internal chamber of the tappet, the end face having a drive surface for co-operating with a drive arrangement, in use, and a plurality of vents through the end face for allowing fluid flow between the internal chamber and an area outside the tappet. A plurality of longitudinal grooves are formed in an internal surface of the side wall portion, the grooves communicating with respective the vents to form a flow path for fluid into the internal chamber.
FILED Tuesday, September 09, 2008
APPL NO 12/283012
ART UNIT 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Pumps
417/273
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215940 Winroth
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Scott Allen Winroth (Ayer, Massachusetts)
ABSTRACT Apparatus for multiplying layers in a composite polymer stream includes an intermediate section having open conduits sandwiched between housing sections that close the conduits. The conduits have respective first stages separated by a first blade extending to a first face, and respective second stages separated by a second blade extending to a second face. The first stages separate the stream into sub-streams and compress and shift the sub-streams in a first dimension, whereas the second stages shift the sub-streams in a second dimension. In order to maintain a constant cross-sectional area of the sub-streams, the housing sections may be provided with complementary open channels. The apparatus can be used to multiply layers which are side-by-side or one-over-another by changing orientation in the direction of flow.
FILED Friday, March 20, 2009
APPL NO 12/383136
ART UNIT 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Plastic article or earthenware shaping or treating: Apparatus
425/132
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216012 Bona et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Samuel R. Bona (La Mesa, California);  Timothy J. Keenan (San Diego, California);  Joshua D. Bianchi (San Diego, California)
ABSTRACT Deployment of a moored undersea device is achieved by fixing a mooring line to an anchor, and allowing the mooring line to unwind from a winding reel. A winding reel control mechanism is responsive to underwater hydrostatic pressure to release the mooring line when the hydrostatic pressure exceeds a predetermined level. When the hydrostatic pressure falls below the predetermined level, the winding reel control mechanism prevents further pay out of the mooring line.
FILED Monday, December 14, 2009
APPL NO 12/637453
ART UNIT 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Buoys, rafts, and aquatic devices
441/25
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US 08216401 Fronabarger et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Pacific Scientific Energetic Materials Company (Chandler, Arizona)
INVENTOR(S) John W. Fronabarger (Sun Lakes, Arizona);  Michael D. Williams (Gilbert, Arizona)
ABSTRACT Embodiments of the present subject matter provide an improved percussion primer composition and improved hot-wire igniter acceptor, wherein lead styphnate is replaced with a lead-free material, 4,6-dinitro-7-hydroxybenzofuroxan, potassium salt (KDNP). Embodiments of the percussion primer composition include KDNP, a sensitizer, an oxidizer, calcium silicide, a fuel, and a binder. Embodiments of the hot-wire igniter device include a bridgewire, an acceptor, and an output, where KDNP is the acceptor. Power supply may be in the form of constant current/voltage or current flow from a capacitor discharge. Certain embodiments utilize a variety of output formulations, such as BKNO3, black powder, and Red Dot double base propellant.
FILED Thursday, October 06, 2011
APPL NO 13/267009
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Explosive and thermic compositions or charges
149/109.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216403 Shortridge et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Robert G. Shortridge (Bloomington, Indiana);  Christina M. Yamamoto (Bloomington, Indiana)
ABSTRACT Perchlorate-free flare compositions are disclosed which, when burned, produce red smoke and flames. Methods of producing the compositions are also disclosed.
FILED Friday, January 14, 2011
APPL NO 13/007200
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Explosive and thermic compositions or charges
149/109.600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216404 Singh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Sanjeev K. Singh (Dover, New Jersey);  Philip Samuels (Manville, New Jersey);  Christos Capellos (Morris Plains, New Jersey);  Barry Fishburn (Dover, New Jersey)
ABSTRACT A process for manufacture of explosive formulations containing a halogenated wax binder, involving dilution of the halogenated wax in a non-aqueous lacquer, slurring the explosive in an aqueous solution and applying heat and vacuum to yield a granular explosive which provides complete coating to avoid hot spots and is quickly pressable at lower temperature and pressure.
FILED Tuesday, January 25, 2011
APPL NO 13/013008
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Explosive and thermic compositions or charges
149/109.600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216701 Cole
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Melanie Will Cole (Churchville, Maryland)
ABSTRACT A compositionally stratified multi-layer Ba1-xSrxTiO3 (BST) heterostructure material is described which includes a lower layer of crystallized Ba1-xSrxTiO3 perovskite oxide where x is in the range of 0.36-0.44, inclusive, deposited on a substrate; an intermediate layer of crystallized Ba1-xSrxTiO3 perovskite oxide where x is in the range of 0.23-0.27, inclusive, in contact with the lower layer; and an upper layer of crystallized Ba1-xSrxTiO3 perovskite oxide where x in the range of 0.08-0.13, inclusive, in contact with the intermediate layer. A phase shifter and/or preselector tunable device including a compositionally stratified multi-layer BST hererostructure material is described according to the present invention. Temperature sensitivity of an inventive phase shifter is reduced by at least 70% in the temperature interval of 20 to 90° C., inclusive, and by at least 14% in the temperature interval of −10 to 20° C., inclusive, compared to a compositionally homogeneous 60/40 BST material.
FILED Wednesday, April 13, 2011
APPL NO 13/085987
ART UNIT 1784 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/697
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US 08216779 Manuelidis
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Laura Manuelidis (New Haven, Connecticut)
ABSTRACT Stable cell lines which produce the pathological form of PrP after infection with the infectious agent for CJD provide a high throughput assay to identify suitable treatment protocols and compositions. The stable cell lines also provide rich source of infectious CJD agent. They also may be used to identify vaccine candidates. Co-culture of neuronal cells with cells to be tested for infection with a TSE agent also provides a high throughput method for identifying infected cells.
FILED Monday, April 11, 2011
APPL NO 13/084316
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216797 Schwoebel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Eric Schwoebel (Woburn, Massachusetts);  James Harper (Jamaica Plain, Massachusetts);  Martha S. Petrovick (Barre, Massachusetts);  Frances Nargi (Littleton, Massachusetts);  Mark Hollis (Concord, Massachusetts);  Bernadette Johnson (Hollis, New Hampshire);  Joseph Lacirignola (Beverly, Massachusetts);  Richard Mathews (Chelmsford, Massachusetts);  Kristine Hogan (Danvers, Massachusetts);  Trina Vian (Groton, Massachusetts);  Allan Heff (Newton, Massachusetts);  Mark Hennessy (Falls Church, Virginia);  Songeeta Palchaudhuri (Somerville, Massachusetts);  Todd Rider (Littleton, Massachusetts)
ABSTRACT The invention described herein provides methods for the detection of target particles, such as pathogens, soluble antigens, nucleic acids, toxins, chemicals, plant pathogens, blood borne pathogens, bacteria, viruses and the like. Also described is an emittor cell comprising a receptor, wherein the receptor can be an antibody or an Fc receptor, and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more receptors on the emittor cell. Also provided are optoelectronic sensor devices for detecting a target particle in a sample, including in a plurality of samples.
FILED Thursday, November 30, 2006
APPL NO 12/085495
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216910 Chen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
APPLICANT(S)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Mary Chen (Oak Park, California);  Marko Sokolich (Los Angeles, California)
ABSTRACT A wafer comprising at least one high Ft HBT and at least one high BVceo HBT having various collector profiles on a common III-V compound semiconductor based wafer. The N+ implant in the collector varies the collector profiles of individual HBTs on the wafer. The method for preparing the device comprises forming of HBT layers up to and including collector layer on non-silicon based substrate, performing ion implantation, annealing for implant activation, and forming remaining HBT layers.
FILED Thursday, June 04, 2009
APPL NO 12/478628
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/312
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216969 Lombardi
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) John L. Lombardi (Tucson, Arizona)
ABSTRACT A pathogen-resistant fabric comprising one or more photocatalysts capable of generating singlet oxygen from ambient air. The pathogen-resistant fabric may optionally include one or more singlet oxygen traps.
FILED Tuesday, March 29, 2011
APPL NO 13/075051
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/438
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US 08217194 Kolel-Veetil et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Manoj K. Kolel-Veetil (Alexandria, Virginia);  Teddy M Keller (Fairfax Station, Virginia)
ABSTRACT Disclosed herein are the compounds shown below. Each R is an organic group, Cb is a carborane group, and —C6H4— is phenylene. The value of each m is a nonnegative integer, q is 0 or 1, with the proviso that if q is 0 then m is 0 or 1, p is a positive integer, r is a positive integer, and n is an integer greater than or equal to 10. Also disclosed are methods of making and crosslinking the compounds.
—{SiR2—([O]q—SiR2)m-[Cb-SiR2—([O]q—SiR2)m]p—C≡C—C6H4—C≡C}—
—{SiR2—(O—SiR2)m—C≡C—C6H4—C≡C}n—;
—{SiR2—([O]q—SiR2)m—[C≡C—C6H4—C≡C—SiR2—([O]q—SiR2)m]p-Cb-[SiR2—([O]q—SiR2)m-Cb]r}-
FILED Friday, June 10, 2011
APPL NO 13/157573
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Organic compounds
556/403
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US 08217318 Wood-Putnam et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Jody Wood-Putnam (Panama City, Florida);  Marshall L Nuckols (Panama City, Florida);  Kenneth Price (Panama City, Florida)
ABSTRACT The invention is a submersible hand warmer apparatus for warming a diver's gloved hands. The apparatus includes a sleeve having a center portion with an elongate chamber with a right access port and a left access port; and right and left sleeve portions with elastic cuffs. The cuffs can be stretched allowing the diver's gloved hands access to the chamber, and then retract, forming a seal against the diver's arms. The chamber is sized for enough heat transfer fluid, such as water, so that the temperature of the diver's hands is raised to at least 54° F. upon immersion of his hands in the water. The apparatus also includes a heating component; an energy source, such as a battery; a housing which provides structural support; an insulation that slows the loss of heat to the cold ambient water; and a controller that controls the rate that energy is consumed.
FILED Friday, December 04, 2009
APPL NO 12/653415
ART UNIT 2827 — Semiconductors/Memory
CURRENT CPC
Electric heating
219/482
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217382 Ptasinski et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Joanna N. Ptasinski (San Diego, California);  Stephen D. Russell (San Diego, California);  J. Scott Rodgers (Arlington, Virginia)
ABSTRACT An optical-powered device includes a flexible substrate, a photonic bandgap layer coupled thereto, a waveguide contained within the photonic bandgap layer, and a dendrimer region contained within the waveguide. The dendrimer region may comprise more than one dendrimers. The dendrimer region emission band is within the photonic bandgap of the photonic bandgap layer. Multiple photonic bandgap layers may be included, with one or more waveguides therein. Each waveguide may have a dendrimer region therein. Electronic circuitry may be contained within a portion of the photonic bandgap layer. A light-modulating layer may be directly coupled to the photonic bandgap layer. A portion of the photonic bandgap layer may have a sensing material embedded therein. A cover layer having one or more windows may be coupled to the photonic bandgap layer. Another layer, such as a buffer layer, may be disposed between the substrate layer and the photonic bandgap layer.
FILED Monday, March 01, 2010
APPL NO 12/715241
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/21
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US 08217410 Ma et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin);  Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Zhenqiang Ma (Middleton, Wisconsin);  Weidong Zhou (Mansfield, Texas)
ABSTRACT Vertical cavity light emitting sources that utilize patterned membranes as reflectors are provided. The vertical cavity light emitting sources have a stacked structure that includes an active region disposed between an upper reflector and a lower reflector. The active region, upper reflector and lower reflector can be fabricated from single or multi-layered thin films of solid states materials (“membranes”) that can be separately processed and then stacked to form a vertical cavity light emitting source.
FILED Friday, March 27, 2009
APPL NO 12/412628
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/98
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217427 Chuang et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Ching-Te K. Chuang (South Salem, New York);  Fadi H. Gebara (Austin, Texas);  Keunwoo Kim (Somers, New York);  Jente Benedict Kuang (Austin, Texas);  Hung C. Ngo (Austin, Texas)
ABSTRACT A memory circuit includes a plurality of bit line structures, a plurality of word line structures intersecting the plurality of bit line structures to form a plurality of cell locations; and a plurality of cells located at the plurality of cell locations. Each of the cells is selectively coupled to a corresponding one of the bit line structures under control of a corresponding one of the word line structures, and each of the cells in turn includes a logical storage element having at least a first n-type field effect transistor and at least a first p-type field effect transistor. The at least first n-type field effect transistor is formed with a relatively thick buried oxide layer sized to reduce capacitance of the bit line structures, and the at least first p-type field effect transistor is formed with a relatively thin buried oxide layer.
FILED Tuesday, October 02, 2007
APPL NO 11/865780
ART UNIT 2814 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/206
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US 08217495 Blick et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Robert H. Blick (Madison, Wisconsin);  Chulki Kim (Madison, Wisconsin);  Jonghoo Park (Madison, Wisconsin)
ABSTRACT A high-frequency metal-insulator-metal (MIM) type diode is constructed as a bridge suspended above a substrate to significantly reduce parasitic capacitances affecting the operation frequency of the diode thereby permitting improved high-frequency rectification, demodulation, or the like.
FILED Thursday, March 11, 2010
APPL NO 12/721624
ART UNIT 2813 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/594
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217826 Djang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Philipp Arthur Djang (Las Cruces, New Mexico);  Frank Lopez (El Paso, Texas);  Gene E. Herriman (El Paso, New Mexico);  Eduardo Ruiloba, Jr. (El Paso, Texas);  Edward Friday (Las Cruces, New Mexico)
ABSTRACT A process for enhancing radar system survivability against a threat includes the construction of multiple computational radar function chromosomes with each of the chromosomes having values for geometric configuration and operational parameters for at least one radar station emitter and at least one decoy. A genetic algorithm analysis is performed on a computer including a crossover operator and a mutation operator to determine a fitness value for multiple chromosomes against the threat. By configuring and operating the radar system based on a survivability value for the fitness value of the genetic algorithm analysis, radar system survivability against a threat is enhanced. A radar system employing genetic algorithm analysis is also provided.
FILED Tuesday, October 05, 2010
APPL NO 12/897841
ART UNIT 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Communications: Directive radio wave systems and devices
342/13
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217937 Yeoh et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Terence Sern-Wei Yeoh (Pasadena, California);  Neil A. Ives (Hawthorne, California)
ABSTRACT An isosurfacial three-dimensional imaging system and method uses scanning electron microscopy for surface imaging of an assumed opaque object providing a series of tilt images for generating a sinogram of the object and a voxel data set for generating a three-dimensional image of the object having exterior surfaces some of which may be obscured so as to provide exterior three-dimensional surface imaging of objects including hidden surfaces normally obscured from stereographic view.
FILED Wednesday, March 28, 2007
APPL NO 11/729352
ART UNIT 2628 — Selective Visual Display Systems
CURRENT CPC
Computer graphics processing and selective visual display systems
345/424
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218012 DeFlumere et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Space and Missile Defense Command (SMDC)
APPLICANT(S)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Michael E DeFlumere (Winchester, Massachusetts);  William E Shaw (Marlborough, Massachusetts);  Walter P Watson (Lowell, Massachusetts)
ABSTRACT A sensor is used to detect and track a plurality of objects by using a separate track window for each object. Such sensors may be electro optical or infrared. Each object of interest (potential target) in the sensor FOV has a unique track window assigned. This allows independent control of video frame summing for each object to maintain a constant (optimized) signal to noise ratio (SNR) over an extremely large signal dynamic range and reduces track jitter by the simultaneous tracking of multiple objects.
FILED Tuesday, March 18, 2008
APPL NO 12/050344
ART UNIT 2455 — Computer Networks
CURRENT CPC
Television
348/164
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US 08218143 Gupta
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Neelam Gupta (Bethesda, Maryland)
ABSTRACT A method of detecting oxygen and/or chemical content in a subject, comprising generating at least one spectral image of the subject; generating at least one spectral image of a reference object; comparing spectrum from the subject image to the reference image to thereby reveal the relative oxygen content of the subject. A system for determining the level of oxygenation of the blood of a subject body part comprising: a hyperspectral image generator for generating a plurality of spectral images; an image capture device for capturing the spectral images; a processor for generating hyperspectral image cubes such that the spectrum of the body part is extracted and normalized using the spectrum from the reference object to cancel out the spectral response of the light source and the imager; said processor comparing spectral from a subject image to reference images to thereby reveal the relative oxygen content of the subject.
FILED Thursday, January 14, 2010
APPL NO 12/687469
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/326
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218150 Erkmen et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
Multidisciplinary University Research Initiative (MURI)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Baris I. Erkmen (Glendale, California);  Jeffrey H. Shapiro (Sharon, Massachusetts)
ABSTRACT Phase-conjugate optical coherence tomography (PC-OCT) methods and apparatus. PC-OCT may be employed as a three-dimensional imaging technique of interest for biomedical and other imaging applications. It shares much of the source and detection convenience of conventional OCT employing classical light sources, which is in clinical use in ophthalmology and is being developed for a variety of endoscopic optical biopsy instruments. PC-OCT offers a two-fold improvement in axial resolution and immunity to group velocity dispersion, when compared with conventional OCT, that is available from quantum optical coherence tomography (Q-OCT). PC-OCT does this without Q-OCT's need for a non-classical light source and the attendant requirement of photon-coincidence counting detection. Thus, in comparison with Q-OCT, PC-OCT is capable of producing images in measurement times similar to those of conventional OCT.
FILED Tuesday, July 17, 2007
APPL NO 12/309378
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/450
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218345 Callanan et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S)
ASSIGNEE(S) Cree, Inc. (Durham, North Carolina)
INVENTOR(S) Robert Joseph Callanan (Raleigh, North Carolina);  Fatima Husna (Morrisville, North Carolina)
ABSTRACT A rectifier circuit can include an input circuit and first and second silicon carbide (SiC) bipolar junction transistors (BJTs). The input circuit is configured to respond to an alternating current (AC) input signal by generating a first pair of opposite polarity AC signals and a second pair of opposite polarity AC signals. The first pair of AC signals has a greater voltage range than the second pair of AC signals. The first and second SiC BJTs each include an input terminal connected to receive a different one of the second pair of opposite polarity AC signals, a base terminal connected to receive a different one of the first pair of opposite polarity AC signals, and an output terminal connected to a rectified signal output node of the rectifier circuit. The input circuit is further configured to control the first and second SiC BJTs through the first and second pairs of opposite polarity AC signals to forward bias the first SiC BJT while reverse biasing the second SiC BJT during a first half cycle of the AC input signal and to reverse bias the second SiC BJT while forward biasing the second SiC BJT during a second half cycle of the AC input signal.
FILED Friday, March 20, 2009
APPL NO 12/408304
ART UNIT 2838 — Electrical Circuits and Systems
CURRENT CPC
Electric power conversion systems
363/89
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218519 Chamberlain et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Rockwell Collins, Inc. (Cedar Rapids, Iowa)
INVENTOR(S) Scott L. Chamberlain (Cedar Rapids, Iowa);  William B. Curry (Cedar Rapids, Iowa);  Terry J. Hammer (Cedar Rapids, Iowa);  Brian J. Keller (Alburnett, Iowa)
ABSTRACT The present example provides a method of providing a Transmit ID within an ad hoc wireless communications network, and use of the transmit ID to provide methods to select a node's transmit pattern (Transmit Patterns), to inform a node receiver that a packet is incoming that is to be decoded (Receive Packet Acquisition), to tell a node receiver how to efficiently retrieve pulses from multiple packets simultaneously (Efficient Receive Processing), and how to disburse network transmissions throughout network time (Network Traffic Smoothing). The present example may also provide for Network Management of the Transmit IDs for use in network bandwidth reduction and maintenance of the Transmit IDs within the Network.
FILED Wednesday, January 23, 2008
APPL NO 12/009931
ART UNIT 2466 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/343
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218589 Saunders
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) Patrick Saunders (Tijeras, New Mexico)
ABSTRACT A high-energy laser weapon system in which the high-energy laser beam itself is used to correct for atmospheric fluctuations thereby replacing a separate beacon illuminator system. The high-energy laser is turned off (negative pulse) periodically for a very short period giving a wavefront sensor an opportunity to measure the return of the high-energy laser beam from the target. A wavefront sensor drives a deformable mirror based on this return signal avoiding wavelength anisoplanatism. In addition, the high-energy laser weapon can be snapped ahead of the path of the target during the negative pulse to avoid tilt anisoplanitism.
FILED Monday, July 28, 2008
APPL NO 12/180702
ART UNIT 2872 — Optics
CURRENT CPC
Coherent light generators
372/33
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218590 Youngner et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Daniel W. Youngner (Maple Grove, Minnesota);  Son T. Lu (Plymouth, Minnesota);  Jeff A. Ridley (Shorewood, Minnesota);  Linda J. Forner (Carver, Minnesota)
ABSTRACT Designs and processes for thermally stabilizing a vertical cavity surface emitting laser (vcsel) in a chip-scale atomic clock are provided. In one embodiment, a Chip-Scale Atomic Clock includes: a vertical cavity surface emitting laser (vcsel); a heater block coupled to a base of the vcsel; a photo detector; a vapor cell, wherein the vapor cell includes a chamber that defines at least part of an optical path for laser light between the vcsel and the photo detector; and an iso-thermal cage surrounding the vcsel on all sides, the iso-thermal cage coupled to the heater block via a thermally conductive path.
FILED Friday, September 17, 2010
APPL NO 12/884489
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/34
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218597 Fay et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia)
INVENTOR(S) Josiah W. Fay (Highland Park, New Jersey);  Joseph Leone (Oak Ridge, New Jersey);  Henry Kerwien (Augusta, New Jersey);  Thomas DeVoe (Lake Hopatcong, New Jersey);  Gregory Burke (Hanover, New Hampshire);  Arthur A. Karpinski (Jordan, New York)
ABSTRACT A diode pumped solid-state laser for high shock, high vibration environments such as those found in laser ignition systems for artillery systems.
FILED Monday, May 05, 2008
APPL NO 12/115195
ART UNIT 2828 — Semiconductors/Memory
CURRENT CPC
Coherent light generators
372/70
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218692 Lorenzelli
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
The Aerospace Corporation (AEROSPACE)
Federally Funded Research and Development Center (FFRDC)
Operated by The Aerospace Corporation (AEROSPACE) at El Segundo, CA
APPLICANT(S)
ASSIGNEE(S) The Aerospace Corporation (El Segundo, California)
INVENTOR(S) Flavio Lorenzelli (Los Angeles, California)
ABSTRACT A device for separating uncoordinated co-channel signals including a symbol detector.
FILED Thursday, December 10, 2009
APPL NO 12/635670
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/341
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218828 Iasso
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S)
ASSIGNEE(S) Anthony S. Iasso (Haymarket, Virginia)
INVENTOR(S) Anthony S. Iasso (Haymarket, Virginia)
ABSTRACT A method identifies persons based on biometric information. The method includes providing a cache of biometric templates. The cache stores segments of the biometric templates associated with biometric features contained in the segments. The method also includes receiving a sample biometric template to be identified; dividing the sample biometric template into jobs based on the biometric features contained in the sample biometric template; comparing the jobs to the segments corresponding to the biometric features of the sample biometric template to determine candidate biometric templates associated with the segments that match the jobs; and generating a candidates list identifying the candidate biometric templates and entities related to the candidate biometric templates.
FILED Friday, December 28, 2007
APPL NO 11/966333
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/115
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218971 Preston et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) Steven Preston (Winter Springs, Florida);  Edward S. Kaprocki (Debary, Florida);  Thomas H. Penner (Apopka, Florida)
ABSTRACT A processor can determine a relative position within a room of a person wearing a force-on-force device based exclusively upon sensed optical signals detected by optical sensors connected to the force-on-force device. Each of the sensed optical signals is geographically focused within a spatially constrained zone. Each sensed optical signal can further include digitally encoded data indicating an optical source that emitted the sensed optical signal and a spatially constrained zone of the sensed optical signal. The relative position can be determined based on determining a grid within the room within which the person is located. The grid can be defined by overlapping ones of the spatially constrained zones of the sensed optical signals.
FILED Friday, January 08, 2010
APPL NO 12/684712
ART UNIT 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Optical communications
398/135
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08219023 Pezeshkian et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Narek Pezeshkian (Glendale, California);  Aaron Burmeister (San Diego, California);  Hoa Nguyen (San Diego, California)
ABSTRACT A system includes a substrate having a first side and a second side, more than one optical sources, wherein at least one optical source is coupled to the first side and at least one optical source is coupled to the second side, a power source operatively connected to the optical sources, a switch connected to the power source, and an RF receiver connected to the switch. The optical sources may be LEDs and may operate within the visible or infrared spectrum. The system may include an enclosure that is configured to be attached to antenna masts of a radio relay device. The enclosure may have windows to allow light from the optical sources to pass unobstructed through the enclosure. In some embodiments, the system is contained within the radio relay device. The system may be remotely controlled to illuminate a distant object or structure.
FILED Tuesday, March 16, 2010
APPL NO 12/725237
ART UNIT 2618 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Telecommunications
455/11.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08219264 Blake
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Air Force (Washington, District of Columbia)
INVENTOR(S) William B. Blake (Xenia, Ohio)
ABSTRACT A close formation flight positioning system uses only air data measurements without a data link. The wake vortex of a lead aircraft generates horizontal, vertical and lateral induced velocities that vary with horizontal, vertical and lateral position from its wing. Two or more laterally or vertically separated air data sensors on a follower aircraft measure impact pressure, angle of attack and angle of sideslip, which are converted to horizontal, vertical and lateral velocity components. By comparing these velocity component measurements, using the distance between the sensors on the follower aircraft and the wing span of the lead aircraft, the distance from the follower to the lead aircraft can be determined. If weight, speed and altitude of the lead aircraft are known, then two sensors on the follower aircraft are sufficient to determine relative positions. If those conditions are not known, then three sensors on the follower aircraft are needed.
FILED Monday, June 08, 2009
APPL NO 12/479889
ART UNIT 3616 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/3
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08219267 Hamke et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Tank-Automotive and Armaments Command (TACOM)
APPLICANT(S)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Eric E. Hamke (Albuquerque, New Mexico);  Dale F. Enns (Roseville, Minnesota);  Gregory R. Loe (Friendswood, Texas);  Roger A. Wacker (Houston, Texas);  Oliver Schubert (Albuquerque, New Mexico)
ABSTRACT The speed of the wind during operation of a UAV is estimated. In one example the speed of the wind is estimated by modeling an acceleration of an unmanned aerial vehicle (UAV) based on a measured ground speed of the UAV, determining an actual acceleration of the UAV with one or more sensors, and estimating the speed of the wind as an integral of a difference between the modeled acceleration and the actual acceleration.
FILED Thursday, May 27, 2010
APPL NO 12/789238
ART UNIT 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/14
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08219357 Piggott et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S)
ASSIGNEE(S) Rochester Institute of Technology (Rochester, New York)
INVENTOR(S) Christopher Piggott (Pittsford, New York);  Edward McCarthy (Pittsford, New York);  Michael G. Thurston (Penfield, New York);  Sean McConky (Lockport, New York)
ABSTRACT A method and system for displaying asset health information includes determining a status of at least one asset in a monitored system based on operational information obtained about the at least one asset. The obtained operational information about the at least one asset is compared against other operational information obtained about the monitored system. A review of the determined status of the at least one asset is conducted based on the comparison. At least one of textual information and numeric information is displayed based on the conducted review of the determined status of the at least one asset. Additionally, at least one of three or more indicator lights is displayed based on the conducted review of the determined status of the at least one asset.
FILED Friday, March 21, 2008
APPL NO 12/053079
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/183
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08219391 Preuss et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Communications-Electronics Command (CECOM)
APPLICANT(S)
ASSIGNEE(S) Raytheon BBN Technologies Corp. (Cambridge, Massachusetts)
INVENTOR(S) Robert David Preuss (Sagamore Beach, Massachusetts);  Darren Ross Fabbri (Arlington, Massachusetts);  Daniel Ramsay Cruthirds (Cambridge, Massachusetts)
ABSTRACT Presented herein are systems and methods for processing sound signals for use with electronic speech systems. Sound signals are temporally parsed into frames, and the speech system includes a speech codebook having entries corresponding to frame sequences. The system identifies speech sounds in an audio signal using the speech codebook.
FILED Monday, November 06, 2006
APPL NO 11/593836
ART UNIT 2626 — Selective Visual Display Systems
CURRENT CPC
Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression
74/214
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US 08219848 Branson et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Michael John Branson (Rochester, Minnesota);  Frederick Douglis (Basking Ridge, New Jersey);  Bradley William Fawcett (Byron, Minnesota);  Zhen Liu (Tarrytown, New York);  Bin Rong (Melbourne, Australia);  Fan Ye (Yorktown Heights, New York)
ABSTRACT A failure recovery framework to be used in cooperative data stream processing is provided that can be used in a large-scale stream data analysis environment. Failure recovery supports a plurality of independent distributed sites, each having its own local administration and goals. The distributed sites cooperate in an inter-site back-up mechanism to provide for system recovery from a variety of failures within the system. Failure recovery is both automatic and timely through cooperation among sites. Back-up sites associated with a given primary site are identified. These sites are used to identify failures within the primary site including failures of applications running on the nodes of the primary site. The failed applications are reinstated on one or more nodes within the back-up sites using job management instances local to the back-up sites in combination with previously stored state information and data values for the failed applications. In additions to inter-site mechanisms, each one of the plurality of sites employs an intra-site back-up mechanism to handle failure recoveries within the site.
FILED Tuesday, April 10, 2007
APPL NO 11/733724
ART UNIT 2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/3
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Health and Human Services (HHS) 

US 08214999 Miles
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
APPLICANT(S)
ASSIGNEE(S) The Research Foundation of State University of New York (Binghamton, New York)
INVENTOR(S) Ronald N. Miles (Newark Valley, New York)
ABSTRACT A differential microphone having a perimeter slit formed around the microphone diaphragm that replaces the backside hole previously required in conventional silicon, micromachined microphones. The differential microphone is formed using silicon fabrication techniques applied only to a single, front face of a silicon wafer. The backside holes of prior art microphones typically require that a secondary machining operation be performed on the rear surface of the silicon wafer during fabrication. This secondary operation adds complexity and cost to the micromachined microphones so fabricated. Comb fingers forming a portion of a capacitive arrangement may be fabricated as part of the differential microphone diaphragm.
FILED Thursday, August 04, 2011
APPL NO 13/198113
ART UNIT 3729 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/594
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215186 Macomber et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Orthocare Innovations LLC (Oklahoma City, Oklahoma)
INVENTOR(S) Ben Gilbert Macomber (Shoreline, Washington);  David Alan Boone (Seattle, Washington);  James Christian Beck (Missoula, Montana)
ABSTRACT A computerized prosthesis alignment system includes a transducer that can measure socket reactions in the anterior/posterior plane and the right/left planes, while canceling or reducing the transverse forces on the measurements of these socket reactions. In addition, the transducer is also capable of determining the axial load or weight experienced by the prosthesis. The computerized prosthesis alignment system is in communication with a host computer. The moment data from the transducer is interpreted by the user via a computer interface. The host computer includes memory for storing one or more applications. These applications receive data from the transducer, interpret the data with discrete algebraic or fuzzy logic algorithms, and display the output numerically and graphically. Applications may also interpret the data to provide analyses to the user for aligning the prosthesis.
FILED Thursday, January 06, 2011
APPL NO 12/986024
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/862.44
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216148 Amadio et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)
ASSIGNEE(S) Mayo Foundation for Medical Education and Research (Rochester, Minnesota)
INVENTOR(S) Peter C. Amadio (Rochester, Minnesota);  Chunfeng Zhao (Rochester, Minnesota);  Kai-Nan An (Rochester, Minnesota);  Marek Belohlavek (Rochester, Minnesota);  Mark E. Zobitz (Rochester, Minnesota)
ABSTRACT This disclosure describes methods for detecting early stages of disease, in particular carpal tunnel syndrome, by using cooperative ultrasound techniques. In a particular embodiment, a grayscale ultrasonogram may be used to detect local anatomical features within the carpal tunnel by physically moving a tendon and identifying the corresponding feature on the ultrasonogram display device. A high-resolution color Doppler ultrasound device may then be used to interrogate features of anatomy surrounding the tendon for disease. In a particular embodiment, the color Doppler ultrasound device may be used to measure the velocities of the tendon and surrounding anatomy, in particular the sub-synovial connective tissue; the resultant data may be used to quantify certain anatomical anomalies, indicative or non-indicative of carpal tunnel syndrome.
FILED Monday, July 02, 2007
APPL NO 11/772706
ART UNIT 3737 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Surgery
6/453
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216434 Hsiai et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S)
ASSIGNEE(S) University of Southern California (Los Angeles, California)
INVENTOR(S) Tzung K. Hsiai (Santa Monica, California);  Gopikrishnan Soundararajan (Alisa Viejo, California);  Eun Sok Kim (Rancho Palos Verdes, California);  Hongyu Yu (Mesa, Arizona);  Mahsa Rouhanizadeh (Newport Beach, California);  Christina Tiantian Lin (Santa Rosa, California)
ABSTRACT A micromachined sensor for measuring vascular parameters, such as fluid shear stress, includes a substrate having a front-side surface, and a backside surface opposite the front-side surface. The sensor includes a diaphragm overlying a cavity etched within the substrate, and a heat sensing element disposed on the front-side surface of the substrate and on top of the cavity and the diaphragm. The heat sensing element is electrically couplable to electrode leads formed on the backside surface of the substrate. The sensor includes an electronic system connected to the backside surface and configured to measure a change in heat convection from the sensing element to surrounding fluid when the sensing element is heated by applying an electric current thereto, and further configured to derive from the change in heat convection vascular parameters such as the shear stress of fluid flowing past the sensing element.
FILED Monday, March 03, 2008
APPL NO 12/041577
ART UNIT 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical and wave energy
24/192.150
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216565 Restifo et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Nicholas P. Restifo (Chevy Chase, Maryland);  Lydie Cassard (Antony, France);  Zhiya Yu (Potomac, Maryland);  Steven A. Rosenberg (Potomac, Maryland)
ABSTRACT The invention provides human cells, particularly human T cells, comprising a murine T Cell Receptor (TCR) having antigen specificity for the cancer antigen gp100. Isolated or purified TCRs having antigenic specificity for amino acids 154-162 of gp100 (SEQ ID NO: 1), as well as related polypeptides, proteins, nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding fragments thereof, conjugates, and pharmaceutical compositions, are further provided. The invention further provides a method of detecting the presence of cancer in a host and a method of treating or preventing cancer in a host comprising the use of the inventive materials described herein.
FILED Friday, January 11, 2008
APPL NO 12/522321
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/93.210
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216568 Plaut et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Tufts Medical Center (Boston, Massachusetts)
INVENTOR(S) Andrew G. Plaut (Lexington, Massachusetts);  Jiazhou Qiu (Westborough, Massachusetts)
ABSTRACT The present invention discloses the use of bacterial IgA1 proteases to treat IgA1 deposition in tissue and organs. Bacterial IgA1 proteases specifically cleave IgA1 molecules and thus provide a means to specifically cleave and remove IgA1 depositions. Accordingly, therapeutic agents for the treatment of diseases characterized by IgA deposition are provided. In particular, therapeutic agents to treat IgA nephropathy, Dermatitis herpetiformis (DH), and Henoch-Schoenlein purpura (HS) are disclosed.
FILED Monday, July 21, 2008
APPL NO 12/177125
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/94.640
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216580 Nawroth et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Roman Nawroth (San Francisco, California);  Steven D. Rosen (San Francisco, California)
ABSTRACT Novel sulfatases and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including various diagnostic and therapeutic agent screening applications. Also provided are methods of inhibiting tumor-induced angiogenesis and methods of treating disease conditions associated therewith, particularly by administering an inhibitor of a subject sulfatase.
FILED Friday, June 27, 2008
APPL NO 12/163761
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/146.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216593 Snell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas);  Imperial College of London (London, United Kingdom)
INVENTOR(S) William J. Snell (Richardson, Texas);  Yanjie Liu (Dallas, Texas);  Robert E. Sinden (Wokingham, United Kingdom);  Oliver Billker (Oxford, United Kingdom);  Rita Tewari (Nottingham, None)
ABSTRACT The present invention includes compositions and methods for the development and use of a vaccine that includes one or more FusM antigens in a carrier adapted to trigger a FusM-specific immune response in the human blood stream.
FILED Saturday, September 15, 2007
APPL NO 11/856036
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/269.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216594 Ko et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Fogarty International Center (FIC)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia);  The Regents of the University of California (Oakland, California);  Cornell Research Foundation, Inc. (Ithaca, New York);  Fundação Oswaldo Cruz-Fiocruz (Rio de Janeiro, Brazil)
INVENTOR(S) Albert I. Ko (Bahia, Brazil);  Mitermayer Galvão Reis (Bahia, Brazil);  Julio Henrique Rosa Croda (Bahia, Brazil);  Isadora Cristina Siqueira (Bahia, Brazil);  David A. Haake (Los Angeles, California);  James Matsunaga (Los Angeles, California);  Lee W. Riley (Berkeley, California);  Michele Barocchi (Florence, Italy);  Tracy Ann Young (Oakland, California)
ABSTRACT The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and their use in diagnostic, therapeutic and vaccine applications. According to the present invention, the isolated molecules encoding for BigL1, BigL2 and BigL3 proteins are used for the diagnosis and prevention of infection with Leptospira species that are capable of producing disease in humans and other mammals, including those of veterinary importance.
FILED Thursday, January 26, 2012
APPL NO 13/359354
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/269.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216777 Biswal et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Shyam Biswal (Ellicott City, Maryland);  Anju Singh (Baltimore, Maryland)
ABSTRACT The invention generally features compositions and methods useful for the treatment and diagnosis of a neoplasia in a subject. In particular, the invention provides therapeutic compositions that decrease the expression of an Nfr2 nucleic acid molecule or polypeptide for the treatment of a neoplasia, such as a chemoresistant neoplasia, in a subject.
FILED Friday, May 26, 2006
APPL NO 11/920907
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216779 Manuelidis
FUNDED BY
Department of Defense (DOD)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Laura Manuelidis (New Haven, Connecticut)
ABSTRACT Stable cell lines which produce the pathological form of PrP after infection with the infectious agent for CJD provide a high throughput assay to identify suitable treatment protocols and compositions. The stable cell lines also provide rich source of infectious CJD agent. They also may be used to identify vaccine candidates. Co-culture of neuronal cells with cells to be tested for infection with a TSE agent also provides a high throughput method for identifying infected cells.
FILED Monday, April 11, 2011
APPL NO 13/084316
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216782 Tong et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S)
ASSIGNEE(S) Cedars-Sinai Medical Center (Los Angeles, California)
INVENTOR(S) Yunguang Tong (Los Angeles, California);  Shlomo Melmed (Los Angeles, California)
ABSTRACT The present invention relates to the use of pituitary tumor transforming gene 1 (PTTG1) as a biomarker for diagnosing cancer as well as for determining cancer treatment responsiveness. In one embodiment, the present invention provides a method of treating cancer by inhibiting the expression of PTTG1, and administering a therapeutically effective amount of Aurora kinase inhibitor, HDAC inhibitor and/or ROS-generating agent.
FILED Friday, March 13, 2009
APPL NO 12/867042
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216783 Khan et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Javed Khan (Derwood, Maryland);  James G. Taylor, VI (Fairfax, Virginia);  Tai Cheuk (Germantown, Maryland)
ABSTRACT This disclosure provides tyrosine kinase protein and nucleic acid variants, particularly FGFR4 variants, which are linked to increased risk of tumor metastasis. The disclosure further provides methods of diagnosis and prognosis, and development of new therapeutic agents using these molecules and fragments thereof, and kits for employing these methods and compositions.
FILED Tuesday, April 14, 2009
APPL NO 12/423750
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216788 Caughey et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Byron W. Caughey (Hamilton, Montana);  Ryuichiro Atarashi (Nagasaki, Japan);  Roger A. Moore (Hamilton, Montana)
ABSTRACT The present disclosure relates to methods and compositions for the detection of infectious proteins or prions in samples, including the diagnosis of prion related diseases. One embodiment is an ultrasensitive method for detecting PrP-res (PrPSc) that allows the use of recombinant PrP-sen (rPrP-sen) as a substrate for seeded polymerization. A sample is mixed with purified rPrP-sen to make a reaction mix which is incubated to permit aggregation of the rPrP-sen with the PrP-res that may be present in the sample. Any aggregates are intermittently disaggregated by agitation (for example by sonication) and the reaction allowed to proceed to amplify target substrate. Any rPrP-res(Sc) in the reaction mix is detected to indicate the presence of PrP-res in the original sample. This assay, which is called rPrP-PMCA, is surprisingly much faster than existing PMCA methods, yet it still retains sufficient sensitivity to detect extremely low levels of PrP-res. An alternative of rPrP-PMCA is the QUIC method in which shaking of the reaction mixture is substituted for sonication. The surprising speed and efficiency of the method permits the rapid identification and diagnosis of prion disease, which can limit the transmission of prion diseases, particularly through the food supply.
FILED Monday, July 21, 2008
APPL NO 12/177012
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216789 Disis et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Mary L. Disis (Renton, Washington);  Vivian Goodell (San Diego, California);  Hailing Lu (Seattle, Washington)
ABSTRACT The invention provides a method for detection of a malignancy in a specimen of bodily fluid. The method comprises contacting the specimen with at least two antigens selected from the group consisting of p53, IGFBP2, Topo2α, cathepsin D, cyclin B, cyclin D1, MUC1, HER-2/neu and CEA. The method further comprises incubating the specimen and the antigen for a duration and under conditions that are sufficient for the formation of immunocomplexes; and detecting the presence or absence of immunocomplex formation between the antigens and antibodies specific for the antigens in the specimen, thereby determining the presence or absence of the malignancy. Also provided is a method for monitoring the effectiveness of cancer therapy related to a malignancy in a warm-blooded animal, a method for distinguishing between Stage I and Stage II colorectal cancer in a specimen of bodily fluid.
FILED Friday, February 27, 2009
APPL NO 12/394922
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216796 Mehrad et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
APPLICANT(S)
ASSIGNEE(S) University of Virginia Patent Foundation (Charlottesville, Virginia)
INVENTOR(S) Borna Mehrad (Charlottesville, Virginia);  Marie D. Burdick (Charlottesville, Virginia);  David A. Zisman (Santa Barbara, California);  Michael P. Keane (Dublin, Ireland);  John A. Belperio (Los Angeles, California);  Robert M. Strieter (Charlottesville, Virginia)
ABSTRACT The present invention provides compositions and methods for diagnosing and treating fibrotic lung disease. In one embodiment the diagnostic method comprises determining the amount of circulating CXCL-12 in a patient relative to a control.
FILED Thursday, December 15, 2011
APPL NO 13/327025
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216798 Papadopoulos et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Georgetown University (Washington, District of Columbia)
INVENTOR(S) Vassilios Papadopoulos (North Potomac, Maryland);  Thierry Hauet (Saint Benoit, France)
ABSTRACT The present invention relates to methods, reagents, and kits for assessing organ damage, such as damage due to ischemia reperfusion injury, in the course of a transplantation therapy and/or for assessing organ regeneration following transplantation therapy. The invention provides a method for determining an index of organ health in the course of transplantation therapy comprising measuring the expression level of peripheral-type benzodiazepine receptor (PBR) in the organ. Measuring the expression level of PBR is also useful for assessing the progress of organ regeneration in the course of transplantation therapy by comparing the index of organ health. The expression level of PBR may be used as a predictor of the outcome of transplantation therapy.
FILED Friday, October 01, 2010
APPL NO 12/896522
ART UNIT 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216804 Schultz et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Peter G. Schultz (La Jolla, California);  Jianming Xie (San Diego, California);  Huaqiang Zeng (San Diego, California)
ABSTRACT The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate unnatural amino acids into proteins produced in eubacterial host cells such as E. coli, or in a eukaryotic host such as a yeast cell. The invention provides, for example but not limited to, novel orthogonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing unnatural amino acids, and translation systems.
FILED Thursday, October 27, 2005
APPL NO 11/665083
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216810 Lipkin et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) W. Ian Lipkin (New York, New York);  Thomas Briese (White Plains, New York);  Gustavo Palacios (New York, New York);  Omar Jabado (New York, New York)
ABSTRACT The present invention provides systems and methods for determining the presence or absence of one or more target nucleic acid sequences in a sample. Also provided are kits comprising these systems, and uses of these systems in such applications as determining the presence or absence of at least one target nucleic acid sequence in a sample, detecting microorganism transcripts and host transcripts, differentiating microorganism transcripts from host transcripts, screening blood products, assaying a food product for contamination, assaying a sample for environmental contamination, detecting genetically-modified organisms, biodefense, forensics, and genetic-comparability studies. The present invention further provides a complex that includes a target nucleic acid sequence, a capture nucleic acid, and a reporter nucleic acid.
FILED Tuesday, April 27, 2004
APPL NO 10/833791
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216832 Battrell et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) Micronics, Inc. (Redmond, Washington)
INVENTOR(S) C. Frederick Battrell (Redmond, Washington);  Jason Capodanno (Redmond, Washington);  John Clemmens (Redmond, Washington);  Joan Haab (Seattle, Washington);  John Gerdes (Columbine Valley, Colorado)
ABSTRACT Biohazard specimen collection containers are provided with an external disposable skin, that is stripped away and discarded after the biohazardous specimen is collected, thus reducing or eliminating objectionable or dangerous residues on the outside surfaces of the container. Further, we teach that the sample collection container with external disposable skin may also serve as an integrated microfluidic biosample processing and analytical device, thereby providing a single entry, disposable assay unit, kit and system for “world-to-result” clinical diagnostic testing. These integrated assay devices are provided with synergic, multiple safe-handling features for protecting healthcare workers who handle them. The modified collection containers and analytical devices find application, for example, in PCR detection of infectious organisms or pathogenic markers collected on a swab.
FILED Thursday, January 28, 2010
APPL NO 12/695487
ART UNIT 1775 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/309.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216835 Pagano et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) New York University (New York, New York)
INVENTOR(S) Michele Pagano (New York, New York);  Florian Bassermann (New York, New York)
ABSTRACT The invention relates to modulating Cdc14B levels (cell division cycle 14 homolog B) and/or Cdh1 (Fzr1 protein, CDC20-like 1b, or fizzy-related protein) levels to sensitize cells to DNA damage by increasing the abundance of Plk1 (polo-like kinase 1) in a target cell. In certain embodiments, the invention relates to modulating Plk1 levels, and in particular to increasing Plk1 levels, to sensitize target cells such as cancer cells to cell death or apoptosis. In certain embodiments, the invention relates to inhibitors of Cdc14B and Cdh1 that sensitize tumor cells to chemotherapy or radiation induced cell death or apoptosis. In addition to applications relating to cancer therapies and diagnostics, the Plk1 modulators and assays will be employed for identifying novel drugs or drug candidates useful for various proliferative and/or differentiative disorders such as major opportunistic infections, immune disorders, cardiovascular diseases and inflammatory disorders.
FILED Wednesday, July 08, 2009
APPL NO 12/499208
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
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US 08217001 Cowley et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S) Imperial Innovations Limited (, None);  Oregon Health and Science University (, None)
INVENTOR(S) Michael Cowley (Portland, Oregon);  Roger Cone (Oregon City, Oregon);  Malcolm Low (Lake Oswego, Oregon);  Andrew Butler (Baton Rouge, Louisiana);  Stephen Robert Bloom (London, United Kingdom);  Caroline Jane Small (London, United Kingdom);  Rachel Louise Batterham (London, United Kingdom);  Mohammad Ali Ghatei (London, United Kingdom)
ABSTRACT Methods are disclosed for decreasing calorie intake, food intake, and appetite in a subject. The methods include peripherally administering a therapeutically effective amount of PYY or an agonist thereof to the subject, thereby decreasing the calorie intake of the subject.
FILED Friday, August 29, 2008
APPL NO 12/202197
ART UNIT 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/5.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217020 Sarnow et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Peter Sarnow (Palo Alto, California);  Catherine L. Jopling (Liverpool, United Kingdom);  Alissa M. Lancaster (Portland, Oregon)
ABSTRACT Methods and compositions for reducing viral genome amounts in a target cell are provided. In the subject methods, the activity of a miRNA is inhibited in a manner sufficient to reduce the amount of viral genome in the target cell, e.g., by introducing a miRNA inhibitory agent in the target cell. Also provided are pharmaceutical compositions, kits and systems for use in practicing the subject methods. The subject invention finds use in a variety of applications, including the treatment of subjects suffering from a viral mediated disease condition, e.g., an HCV mediated disease condition.
FILED Friday, November 19, 2010
APPL NO 12/950672
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
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US 08217026 Crapo et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Aeolus Sciences, Inc. (Mission Viejo, California);  National Jewish Health (Durham, North Carolina);  Duke University (Denver, Colorado)
INVENTOR(S) James D. Crapo (Englewood, Colorado);  Brian J. Day (Englewood, Colorado);  Michael P. Trova (Schenectady, New York);  Polvina Jolicia F. Gauuan (Albany, New York);  Douglas B. Kitchen (Schenectady, New York);  Irwin Fridovich (Durham, North Carolina);  Ines Batinic-Haberle (Durham, North Carolina)
ABSTRACT The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also relates to compounds and compositions suitable for use in such methods.
FILED Friday, September 17, 2010
APPL NO 12/885198
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/185
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US 08217072 Fenical et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) William H. Fenical (Del Mar, California);  Paul R. Jensen (San Diego, California);  Tracy J. Mincer (San Diego, California);  Robert H. R. Feling (Eppstein-Bremthal, Germany)
ABSTRACT The present invention is based on the discovery that certain fermentation products of the marine actinomycete strains CNB392 and CNB476 are effective inhibitors of hyperproliferative mammalian cells. The CNB392 and CNB476 strains lie within the family Micromonosporaceae, and the generic epithet Salinospora has been proposed for this obligate marine group. The reaction products produced by this strain are classified as salinosporamides, and are particularly advantageous in treating neoplastic disorders due to their low molecular weight, low IC50 values, high pharmaceutical potency, and selectivity for cancer cells over fungi.
FILED Friday, June 18, 2004
APPL NO 10/561711
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/421
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US 08217076 Williams et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) Colorado State University Research Foundation (Fort collins, Colorado);  Dana-Farber Cancer Institute (Boston, Massachusetts)
INVENTOR(S) Robert M. Williams (Fort Collins, Colorado);  James E. Bradner (Cambridge, Massachusetts);  Albert Bowers (Boston, Massachusetts);  Tenaya Newkirk (Fort Collins, Colorado)
ABSTRACT Analogs of largazole are described herein. Methods of treating cancer and blood disorders using largazole and largazole analogs and pharmaceutical compositions comprising the same are additionally described herein. Methods for preparing largazole analogs are likewise described.
FILED Thursday, July 16, 2009
APPL NO 12/504508
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/539
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US 08217138 May et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Michael J. May (New Haven, Connecticut);  Sankar Ghosh (Madison, Connecticut)
ABSTRACT The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti-inflammatory compounds and methods of inhibiting NF-κB-dependent target gene expression in a cell.
FILED Monday, August 08, 2011
APPL NO 13/204919
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/300
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US 08217145 Wang et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scrips Research Institute (La Jolla, California)
INVENTOR(S) Jiangyun Wang (La Jolla, California);  Peter G. Schultz (La Jolla, California)
ABSTRACT The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the unnatural amino acid phenylselenocysteine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal aminoacyl-tRNA synthetases, polynucleotides encoding the novel synthetase molecules, methods for identifying and making the novel synthetases, methods for producing proteins containing the unnatural amino acid phenylselenocysteine and translation systems. The invention further provides methods for producing modified proteins (e.g., lipidated proteins) through targeted modification of the phenylselenocysteine residue in a protein.
FILED Tuesday, March 13, 2007
APPL NO 12/225261
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
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US 08217157 Chaudhry et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Hina W. Chaudhry (New York, New York);  Debra J. Wolgemuth (New York, New York)
ABSTRACT The present invention provides methods for promoting generation of heart tissue, and for treating and preventing heart tissue degeneration. Additionally, the present invention provides a therapeutic composition comprising a cyclin-associated agent, and a kit comprising the composition. The present invention further provides a heart tissue cell, a sidepopulation progenitor cell, and a stem cell in which cyclin is augmented. Also provided are cell lines comprising these cells, screening methods using the cell lines, and drugs identified by these methods. The present invention further provides in vitro systems for use in screening candidate drugs for at least one cardiotoxic effect and/or for synergy with cyclin in the treatment and prevention of heart tissue degeneration. Finally, the present invention provides use of a cyclin-associated agent in the generation of heart tissue, and use of a cyclin associated agent in the treatment or prevention of heart tissue degeneration.
FILED Tuesday, May 18, 2004
APPL NO 10/557873
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/23.100
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US 08217158 Neville, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) David M. Neville, Jr. (Bethesda, Maryland);  Jerry Todd Thompson (Frenchville, Pennsylvania);  Huaizhong Hu (Madison, Wisconsin);  Jung-Hee Woo (Rockville, Maryland);  Shenglin Ma (Indianapolis, Indiana);  Jonathan Mark Hexham (S. Orange, New Jersey);  Mary Ellen Digan (Winchester, Massachusetts)
ABSTRACT The present invention described and shown in the specification and drawings provides novel recombinant DT-based immunotoxins, and, more specifically anti-T cell immunotoxin fusion proteins. Also provided are immunotoxins that can be expressed in bacterial, yeast, or mammalian cells. The invention also provides means for expression of the immunotoxin fusion protein. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
FILED Friday, March 05, 2010
APPL NO 12/718673
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Organic compounds
536/23.400
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US 08217161 Baldwin
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S)
ASSIGNEE(S) Clemson University Research Foundation (Clemson, South Carolina)
INVENTOR(S) William S. Baldwin (Seneca, South Carolina)
ABSTRACT The present invention relates to siRNAs that are targeted to RNAs encoding two or more enzymes of a subfamily of cytochrome P450 (CYP) enzymes, along with vectors, cells, and kits comprising the siRNAs. The invention further relates to methods of decreasing expression of two or more CYP subfamily genes in a non-human animal, animals in which expression of two or more CYP subfamily genes has been decreased, and methods of using such animals to study the function of cytochrome P450 enzymes.
FILED Wednesday, April 22, 2009
APPL NO 12/427791
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.500
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217169 Carpino et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Louis A. Carpino (Amherst, Massachusetts);  Jusong Xia (Moore, South Carolina);  Chongwu Zhang (Dayton, New Jersey);  Calin Dan Sferdean (Riverview, Michigan)
ABSTRACT The present invention is directed to compounds of the formula:
or salts thereof or N-oxides and their use in peptide synthesis.
FILED Monday, October 11, 2010
APPL NO 12/901956
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
544/184
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US 08217173 Xu et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Center for Research Resources (NCRR)
APPLICANT(S)
ASSIGNEE(S) Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S) Xiaoming Xu (Mandeville, Louisiana);  Shailaja Jayaramachandran (Arlington, Massachusetts);  Liang Chen (Schaumburg, Illinois)
ABSTRACT Chelating monomers and fluoride-releasing compositions are disclosed that may be incorporated into dental composite restorative materials, dental bonding agents or other dental materials, to produce materials with high fluoride release rates, and high fluoride recharge capability. Such dental restorative materials may help reduce the level of dental caries in patients, particularly the level of caries occurring on the margins of the restorative materials.
FILED Tuesday, February 12, 2008
APPL NO 12/526321
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/10
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217222 Xu et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S)
ASSIGNEE(S) Anticancer, Inc. (San Diego, California);  The United States of America as represented by the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Mingxu Xu (San Diego, California);  Yuying Tan (San Diego, California);  Levy Kopelovich (Annandale, Virginia)
ABSTRACT A method is described to identify secreted proteins identified with stages of malignancy of cancer. The proteins are initially identified by trapping them with a fluorescent protein containing vector that can insert in any gene. The secreted proteins are initially identified by their fluorescence. Secreted proteins identifying tumors with specific degrees of malignancy are isolated to determine if they can serve as markers of cancer progression.
FILED Friday, September 29, 2006
APPL NO 11/529938
ART UNIT 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/3
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US 08217653 Vaughan
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) Regents of the University of Minnesota (Minneapolis, Minnesota)
INVENTOR(S) J. Thomas Vaughan (Stillwater, Minnesota)
ABSTRACT An RF coil system for magnetic resonance applications includes a multi-channel RF coil transceiver and a multi-channel RF coil. The RF coil system is structured for reconfiguration between a plurality of operational modes.
FILED Friday, February 20, 2009
APPL NO 12/390193
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/313
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US 08218152 Marks et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Daniel L. Marks (Chapel Hill, North Carolina);  Stephen A. Boppart (Champaign, Illinois);  Adam M. Zysk (Chicago, Illinois);  Simon C. Schlachter (Wilmette, Illinois)
ABSTRACT A system and method for microscale measurement and imaging of the group refractive index of a sample. The method utilizes a broadband confocal high-numerical aperture microscope embedded into an interferometer and a spectrometric means, whereby spectral interferograms are analyzed to compute optical path delay of the beam traversing the sample as the sample is translated through the focus of an interrogating light beam. A determination of group refractive index may serve to disambiguate phase ambiguity in a measurement of refractive index at a specified wavelength. Spatial resolution of object characterization in three dimensions is achieved by imaging the object from multiple viewpoints.
FILED Wednesday, December 03, 2008
APPL NO 12/326974
ART UNIT 2886 — Optics
CURRENT CPC
Optics: Measuring and testing
356/497
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US 08218841 Kadrmas
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) Dan J. Kadrmas (North Salt Lake, Utah)
ABSTRACT Disclosed herein are embodiments of a rotate-and-slant projector that takes advantage of symmetries in the geometry to compute truly volumetric projections to multiple oblique sinograms in a computationally efficient manner. It is based upon the 2D rotation-based projector using the fast three-pass method of shears, and it conserves the 2D rotator computations for multiple projections to each oblique sinogram set. The projector is equally applicable to both conventional evenly-spaced projections and unevenly-spaced line-of-response (LOR) data (where the arc correction is modeled within the projector). The LOR-based version models the exact location of the direct and oblique LORs, and provides an ordinary Poisson reconstruction framework. Speed optimizations of various embodiments of the projector include advantageously utilizing data symmetries such as the vertical symmetry of the oblique projection process, a coarse-depth compression, and array indexing schemes which maximize serial memory access.
FILED Monday, May 16, 2011
APPL NO 13/108435
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/128
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US 08218889 Zeng
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lke City, Utah)
INVENTOR(S) Gengsheng Lawrence Zeng (Salt Lake City, Utah)
ABSTRACT The present invention provides methods, systems and machine readable medium including machine readable code for deblurring data corrupted by shift variant blurring. A first version of data having shift variant blurring characterized by a first shift variant point spread function is provided. A target shift invariant point spread function is selected. A second shift variant point spread function is derived wherein a combination of the first and second shift variant point spread functions generates the target shift invariant point spread function. The second shift variant point spread function is applied to the first version of the data thereby generating a second version of the data having shift invariant blurring characterized by the target shift invariant point spread function. A linear shift invariant filter is applied to the second version of the data thereby generating a deblurred version of the data.
FILED Friday, November 19, 2010
APPL NO 12/950927
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/255
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US 08218907 Chen et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Guang-Hong Chen (Madison, Wisconsin);  Jie Tang (Madison, Wisconsin)
ABSTRACT A method for reconstructing a high quality image from undersampled image data is provided. The image reconstruction method is applicable to a number of different imaging modalities. Specifically, the present invention provides an image reconstruction method that incorporates an appropriate prior image into an iterative image reconstruction process as well as utilizing an image frame from a previous time frame to constrain the reconstruction of a current image frame.
FILED Wednesday, January 14, 2009
APPL NO 12/353864
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/294
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US 08219191 Hartman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S)
ASSIGNEE(S) Customkynetics, Inc. (Versailles, Kentucky)
INVENTOR(S) Eric C. Hartman (Versailles, Kentucky);  John D. Alton (Lexington, Kentucky);  Tarik S. Aweimrin (Lexington, Kentucky)
ABSTRACT In one aspect, a device facilitates performance of a recumbent stepping exercise using stimulation. The device may include a seat for receiving a human exercise subject and foot receivers for alternately translating to and fro relative to a stationary base along a path of travel between a first position in which the legs are at least partially bent and a second position in which the legs are less bent than in the first position. An electrical stimulator is provided for facilitating the performance of the exercise by the subject moving the foot receivers alternately along the path of travel. In another aspect, adaptive feed-forward control may also be used to enhance the stepping exercise performed using the device. Related methods of performing stepping exercises are also provided.
FILED Monday, August 08, 2011
APPL NO 13/204996
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/2
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US 08219323 Bussemaker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
National Institute of General Medical Sciences (NIGMS)
National Library of Medicine (NLM)
APPLICANT(S)
ASSIGNEE(S) The Trustees of Columbia University in the City of New York (New York, New York)
INVENTOR(S) Harmen J. Bussemaker (New York, New York);  Barrett C. Foat (St. Louis, Missouri);  Ronald G. Tepper (New York, New York)
ABSTRACT Systems and methods for determining free energy parameters for predicting binding affinities of nucleotide sequences are provided. The disclosed subject matter obtains phenotypic measurements for nucleotide sequences (for example a DNA sequence or RNA sequence), links the phenotypic measurements to the nucleotide sequences to obtain linked pairs of phenotypic measurements and nucleotide sequences, estimates a relationship between the phenotypic measurements and the nucleotide sequences using the linked pairs, and obtains sequence specific affinity parameters from the estimated relationship.
FILED Wednesday, May 16, 2007
APPL NO 11/803777
ART UNIT 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/19
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US 08219383 Statnikov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Library of Medicine (NLM)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Alexander Statnikov (Nashville, Tennessee);  Constantin F. Aliferis (Nashville, Tennessee);  Ioannis Tsmardinos (Nashville, Tennessee);  Nafeh Fananapazir (Nashville, Tennessee)
ABSTRACT The invention relates to a method for automatically analyzing data and constructing data classification models based on the data. In an embodiment of the method, the method includes selecting a best combination of methods from a plurality of classification, predictor selection, and data preparatory methods; and determining a best model that corresponds to one or more best parameters of the classification, predictor selection, and data preparatory methods for the data to be analyzed. The method also includes estimating the performance of the best model using new data that was not used in selecting the best combination of methods or in determining the best model; and returning a small set of predictors sufficient for the classification task.
FILED Friday, February 18, 2011
APPL NO 13/030295
ART UNIT 2626 — Selective Visual Display Systems
CURRENT CPC
Data processing: Speech signal processing, linguistics, language translation, and audio compression/decompression
74/8
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Department of Energy (DOE) 

US 08214987 Brock et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Thomas Jefferson National Accelerator Facility (TJNAF)
Federally Funded Research and Development Center (FFRDC)
Operated by Jefferson Science Associates, LLC (JSA) at Newport News, VA
APPLICANT(S)
ASSIGNEE(S) Jefferson Science Associates, LLC (Newport News, Virginia)
INVENTOR(S) James David Brock (Newport News, Virginia);  Christopher D. Keith (Newport News, Virginia)
ABSTRACT A remote vacuum or pressure sealing apparatus and method for making a radiation tolerant, remotely prepared seal that maintains a vacuum or pressure tight seal throughout a wide temperature range. The remote sealing apparatus includes a fixed threaded sealing surface on an isolated system, a gasket, and an insert consisting of a plug with a protruding sample holder. An insert coupling device, provided for inserting samples within the isolated system, includes a threaded fastener for cooperating with the fixed threaded sealing surface on the isolated system. The insert coupling device includes a locating pin for azimuthal orientation, coupling pins, a tooted coaxial socket wrench, and an insert coupling actuator for actuating the coupling pins. The remote aspect of the sealing apparatus maintains the isolation of the system from the user's environment, safely preserving the user and the system from detrimental effect from each respectively.
FILED Tuesday, October 14, 2008
APPL NO 12/287798
ART UNIT 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/255
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US 08215170 Tao et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Arizona Board of Regents (Scottsdale, Arizona)
INVENTOR(S) Nongjian Tao (Scottsdale, Arizona);  Salah Boussaad (Wilmington, Delaware)
ABSTRACT A device for sensing a chemical analyte is disclosed. The device is comprised of a vibrating structure having first and second surfaces and having an associated resonant frequency and a wire coupled between the first and second surfaces of the vibrating structure, wherein the analyte interacts with the wire and causes a change in the resonant frequency of the vibrating structure. The vibrating structure can include a tuning fork. The vibrating structure can be comprised of quartz. The wire can be comprised of polymer. A plurality of vibrating structures are arranged in an array to increase confidence by promoting a redundancy of measurement or to detect a plurality of chemical analytes. A method of making a device for sensing a chemical analyte is also disclosed.
FILED Monday, October 23, 2006
APPL NO 11/568209
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Measuring and testing
073/579
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215392 Rao
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Board of Supervisors of Louisiana State University And Agricultural and Mechanical College (Baton Rouge, Louisiana)
INVENTOR(S) Dandina N. Rao (Baton Rouge, Louisiana)
ABSTRACT A rapid and inexpensive process for increasing the amount of hydrocarbons (e.g., oil) produced and the rate of production from subterranean hydrocarbon-bearing reservoirs by displacing oil downwards within the oil reservoir and into an oil recovery apparatus is disclosed. The process is referred to as “gas-assisted gravity drainage” and comprises the steps of placing one or more horizontal producer wells near the bottom of a payzone (i.e., rock in which oil and gas are found in exploitable quantities) of a subterranean hydrocarbon-bearing reservoir and injecting a fluid displacer (e.g., CO2) through one or more vertical wells or horizontal wells. Pre-existing vertical wells may be used to inject the fluid displacer into the reservoir. As the fluid displacer is injected into the top portion of the reservoir, it forms a gas zone, which displaces oil and water downward towards the horizontal producer well(s).
FILED Friday, April 07, 2006
APPL NO 11/399831
ART UNIT 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware
CURRENT CPC
Wells
166/268
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US 08215489 Roberts et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S)
ASSIGNEE(S) Auburn University (Auburn, Alabama)
INVENTOR(S) Christopher B. Roberts (Auburn, Alabama);  Steven R. Saunders (Auburn, Alabama)
ABSTRACT The present application provides apparatuses and methods for the size-selective fractionation of ligand-capped nanoparticles that utilizes the tunable thermophysical properties of gas-expanded liquids. The nanoparticle size separation processes are based on the controlled reduction of the solvent strength of an organic phase nanoparticle dispersion through increases in concentration of the antisolvent gas, such as CO2, via pressurization. The method of nanomaterial separation contains preparing a vessel having a solvent and dispersed nanoparticles, pressurizing the chamber with a gaseous antisolvent, and causing a first amount of the nanoparticles to precipitate, transporting the solution to a second vessel, pressurizing the second vessel with the gaseous antisolvent and causing further nanoparticles to separate from the solution.
FILED Friday, October 30, 2009
APPL NO 12/610120
ART UNIT 3653 — Material and Article Handling
CURRENT CPC
Classifying, separating, and assorting solids
29/133
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US 08215900 Morrison
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Siemens Energy, Inc. (Orlando, Florida)
INVENTOR(S) Jay A. Morrison (Oviedo, Florida)
ABSTRACT A turbine vane assembly includes an airfoil extending between an inner shroud and an outer shroud. The airfoil can include a substructure having an outer peripheral surface. At least a portion of the outer peripheral surface is covered by an external skin. The external skin can be made of a high temperature capable material, such as oxide dispersion strengthened alloys, intermetallic alloys, ceramic matrix composites or refractory alloys. The external skin can be formed, and the airfoil can be subsequently bi-cast around or onto the skin. The skin and the substructure can be attached by a plurality of attachment members extending between the skin and the substructure. The skin can be spaced from the outer peripheral surface of the substructure such that a cavity is formed therebetween. Coolant can be supplied to the cavity. Skins can also be applied to the gas path faces of the inner and outer shrouds.
FILED Thursday, September 04, 2008
APPL NO 12/204115
ART UNIT 2823 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/115
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US 08215906 Pierce et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Schenectady, New York)
INVENTOR(S) Kirk Gee Pierce (Simpsonville, South Carolina);  Brandon Shane Gerber (Ware Shoals, South Carolina);  Stefan Herr (Greenville, South Carolina)
ABSTRACT The present invention relates to a method of controlling the aerodynamic load of a wind turbine blade by controlling the tip speed ratio (TSR) and/or blade pitch setting of the wind turbine blade so as to optimize power production. A wind turbine blade undergoes an aero-elastic response including deflection and twist that is a function of the blade loading. The blade loading is dependent on the wind speed, TSR, and pitch setting. The aero-elastic response requires a different TSR and/or pitch to be selected throughout the power curve in order to maintain the optimum power production and to improve energy capture.
FILED Friday, February 29, 2008
APPL NO 12/040837
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Fluid reaction surfaces
416/1
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US 08216357 Pickett
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) General Electric Company (Niskayuna, New York)
INVENTOR(S) James Edward Pickett (Schenectady, New York)
ABSTRACT In one aspect of the present invention, a UV-protective coating composition is described. The UV protective coating composition includes an acrylate polymer; and a non-crystallizing UV-absorber composition. The non-crystallizing UV absorber composition includes a dibenzoylresorcinol and at least one triazine compound. The dibenzoylresorcinol is present at a level in the range of from about 10 weight percent to about 25 weight percent, based on the total weight of the coating composition. Also provided is an article that includes the UV protective coating composition, and a method to protect the article.
FILED Friday, September 25, 2009
APPL NO 12/566962
ART UNIT 1762 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compositions: Coating or plastic
16/287.210
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US 08216461 Tabb et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) Farm Group IP LLC (, New Zealand)
INVENTOR(S) Scott J. Tabb (Huntersville, North Carolina);  Ronald P. Rohrbach (Flemington, New Jersey);  Gary B. Zulauf (Findlay, Ohio);  Peter D. Unger (Convent Station, New Jersey);  Weston H. Gerwin (Perrysburg, Ohio);  Daniel E. Bause (Flanders, New Jersey);  Gerard W. Bilski (Perrysburg, Ohio)
ABSTRACT Disclosed herein is an apparatus and method for adding a lubricating additive to a diesel fuel. In one embodiment, a system for controlling the release of a fuel additive into a diesel fuel is provided, the system having: a housing having at least one inlet opening and at least one outlet opening configured to define a flow path therethrough; filter media disposed in the flow path, the filter media comprising an adsorbent that removes sulfur containing compounds from diesel fuel passing through the housing; an additive cartridge configured to disperse a lubricating additive into the diesel fuel; a controller for controlling the amount of lubricating additive that is released from the additive cartridge into the diesel fuel; and at least one sensor configured to monitor the lubricant additive content in the diesel fuel and provide a signal indicative of the lubricant additive content in the diesel fuel to the controller, wherein the controller releases the additive from the additive cartridge based upon the signal received from the at least one sensor.
FILED Tuesday, May 10, 2011
APPL NO 13/104642
ART UNIT 1778 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Liquid purification or separation
210/198.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216674 Simpson et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) Ut-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) John T. Simpson (Clinton, Tennessee);  Brian R. D'Urso (Clinton, Tennessee)
ABSTRACT A superhydrophobic powder is prepared by coating diatomaceous earth (DE) with a hydrophobic coating on the particle surface such that the coating conforms to the topography of the DE particles. The hydrophobic coating can be a self assembly monolayer of a perfluorinated silane coupling agent. The DE is preferably natural-grade DE where organic impurities have been removed. The superhydrophobic powder can be applied as a suspension in a binder solution to a substrate to produce a superhydrophobic surface on the substrate.
FILED Friday, July 13, 2007
APPL NO 11/777486
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/403
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US 08216804 Schultz et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Peter G. Schultz (La Jolla, California);  Jianming Xie (San Diego, California);  Huaqiang Zeng (San Diego, California)
ABSTRACT The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate unnatural amino acids into proteins produced in eubacterial host cells such as E. coli, or in a eukaryotic host such as a yeast cell. The invention provides, for example but not limited to, novel orthogonal synthetases, methods for identifying and making the novel synthetases, methods for producing proteins containing unnatural amino acids, and translation systems.
FILED Thursday, October 27, 2005
APPL NO 11/665083
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/69.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216844 Bodie et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
National Renewable Energy Laboratory (NREL)
Federally Funded Research and Development Center (FFRDC)
Operated by Alliance for Sustainable Energy, LLC (ASE) at Golden, CO
APPLICANT(S)
ASSIGNEE(S) Danisco US Inc. (Palo Alto, California)
INVENTOR(S) Elizabeth A. Bodie (San Carlos, California);  Steve Kim (San Francisco, California)
ABSTRACT The present invention relates to the identification of novel nucleic acid sequences, designated herein as 7p, 8k, 7E, 9G, 8Q and 203, in a host cell which effect protein production. The present invention also provides host cells having a mutation or deletion of part or all of the gene encoding 7p, 8k, 7E, 9G, 8Q and 203, which are presented in FIG. 1, and are SEQ ID NOS.: 1-6, respectively. The present invention also provides host cells further comprising a nucleic acid encoding a desired heterologous protein such as an enzyme.
FILED Tuesday, August 28, 2007
APPL NO 12/376558
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/484
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216965 Krauter et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Paula Krauter (Livermore, California);  David Zalk (San Jose, California);  D. Mark Hoffman (Livermore, California)
ABSTRACT A copolymer and water/ethanol solvent solution capable of binding with airborne contaminants or potential airborne contaminants, such as biological weapon agents or toxic particulates, coagulating as the solvent evaporates, and adhering the contaminants to a surface so as to inhibit the re-suspension of such contaminants. The solution uses a water or ethanol/water mixture for the solvent, and a copolymer having one of several functional group sets so as to have physical and chemical characteristics of high adhesion, low viscosity, low surface tension, negative electrostatic charge, substantially neutral pH, and a low pKa. Use of the copolymer solution prevents re-aerosolization and transport of unwanted, reactive species thus increasing health and safety for personnel charged with decontamination of contaminated buildings and areas.
FILED Monday, August 31, 2009
APPL NO 12/551111
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/401
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216978 Wiesmann et al.
FUNDED BY
Department of Energy (DOE)
Brookhaven Science Associates, LLC (BSA)
Office of Science (DOE-SC)
Brookhaven National Laboratory (BNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Brookhaven Science Associates, LLC (BSA) at Upton, NY
APPLICANT(S)
ASSIGNEE(S) Brookhaven Science Associates, LLC (Upton, New York)
INVENTOR(S) Harold Wiesmann (Stony Brook, New York);  Vyacheslav Solovyov (Rocky Point, New York)
ABSTRACT This invention provides a method of making a fluorinated precursor of a superconducting ceramic. The method comprises providing a solution comprising a rare earth salt, an alkaline earth metal salt and a copper salt; spraying the solution onto a substrate to provide a film-covered substrate; and heating the film-covered substrate in an atmosphere containing fluorinated gas to provide the fluorinated precursor.
FILED Tuesday, February 26, 2008
APPL NO 12/037338
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Superconductor technology: Apparatus, material, process
55/446
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217145 Wang et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S)
ASSIGNEE(S) The Scrips Research Institute (La Jolla, California)
INVENTOR(S) Jiangyun Wang (La Jolla, California);  Peter G. Schultz (La Jolla, California)
ABSTRACT The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetases that can incorporate the unnatural amino acid phenylselenocysteine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal aminoacyl-tRNA synthetases, polynucleotides encoding the novel synthetase molecules, methods for identifying and making the novel synthetases, methods for producing proteins containing the unnatural amino acid phenylselenocysteine and translation systems. The invention further provides methods for producing modified proteins (e.g., lipidated proteins) through targeted modification of the phenylselenocysteine residue in a protein.
FILED Tuesday, March 13, 2007
APPL NO 12/225261
ART UNIT 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217352 Reed
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Bryan W. Reed (Livermore, California)
ABSTRACT A ponderomotive phase plate system and method for controllably producing highly tunable phase contrast transfer functions in a transmission electron microscope (TEM) for high resolution and biological phase contrast imaging. The system and method includes a laser source and a beam transport system to produce a focused laser crossover as a phase plate, so that a ponderomotive potential of the focused laser crossover produces a scattering-angle-dependent phase shift in the electrons of the post-sample electron beam corresponding to a desired phase contrast transfer function.
FILED Monday, September 13, 2010
APPL NO 12/881075
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/311
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US 08217353 Bitter et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S)
ASSIGNEE(S) U.S. Department of Energy (Washington, District of Columbia)
INVENTOR(S) Manfred Ludwig Bitter (Princeton, New Jersey);  Kenneth Wayne Hill (Plainsboro, New Jersey);  Steven Douglas Scott (Wellesley, Massachusetts);  Russell Feder (Newton, Pennsylvania);  Jinseok Ko (Cambridge, Massachusetts);  John E. Rice (N. Billerica, Massachusetts);  Alexander Charles Ince-Cushman (New York, New York);  Frank Jones (Manalapan, New Jersey)
ABSTRACT Arrangements for the point-to-point imaging of a broad spectrum of electromagnetic radiation and ultrasound at large angles of incidence employ matched pairs of spherically bent reflectors to eliminate astigmatic imaging errors. Matched pairs of spherically bent crystals or spherically bent multi-layers are used for X-rays and EUV radiation; and matched pairs of spherically bent mirrors that are appropriate for the type of radiation are used with microwaves, infrared and visible light, or ultrasound. The arrangements encompass the two cases, where the Bragg angle—the complement to the angle of incidence in optics—is between 45° and 90° on both crystals/mirrors or between 0° and 45° on the first crystal/mirror and between 45° and 90° on the second crystal/mirror, where the angles of convergence and divergence are equal. For x-rays and EUV radiation, also the Bragg condition is satisfied on both spherically bent crystals/multi-layers.
FILED Wednesday, May 06, 2009
APPL NO 12/436708
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/336.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217359 Kross et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Thomas Jefferson National Accelerator Facility (TJNAF)
Federally Funded Research and Development Center (FFRDC)
Operated by Jefferson Science Associates, LLC (JSA) at Newport News, VA
APPLICANT(S)
ASSIGNEE(S) Jefferson Science Associates, LLC (Newport News, Virginia)
INVENTOR(S) Brian J. Kross (Yorktown, Virginia);  John McKisson (Hampton, Virginia);  Aleksandr Stolin (Morgantown, West Virginia);  Andrew G. Weisenberger (Yorktown, Virginia);  Carl Zorn (Yorktown, Virginia)
ABSTRACT A self-aligning collimator for a radiation imaging device that is secured and aligned through the use of a plurality of small magnets. The collimator allows for the rapid exchange, removal, or addition of collimators for the radiation imaging device without the need for tools. The accompanying method discloses the use of magnets and accompanying magnetic fields to align and secure collimators in a radiation imaging assembly.
FILED Monday, July 11, 2011
APPL NO 13/135615
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/370.90
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217381 Rogers et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Materials Sciences and Engineering Division (MSE)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) John A. Rogers (Champaign, Illinois);  Matthew Meitl (Raleigh, North Carolina);  Yugang Sun (Naperville, Illinois);  Heung Cho Ko (Urbana, Illinois);  Andrew Carlson (Urbana, Illinois);  Won Mook Choi (Champaign, Illinois);  Mark Stoykovich (Dover, New Hampshire);  Hanqing Jiang (Urbana, Illinois);  Yonggang Huang (Glencoe, Illinois);  Ralph G. Nuzzo (Champaign, Israel);  Keon Jae Lee (Tokyo, Japan);  Zhengtao Zhu (Rapid City, South Dakota);  Etienne Menard (Durham, North Carolina);  Dahl-Young Khang (Seoul, South Korea);  Seong Jun Kang (Daejeon, South Korea);  Jong Hyun Ahn (Suwon, South Korea);  Hoon-sik Kim (Champaign, Illinois)
ABSTRACT In an aspect, the present invention provides stretchable, and optionally printable, components such as semiconductors and electronic circuits capable of providing good performance when stretched, compressed, flexed or otherwise deformed, and related methods of making or tuning such stretchable components. Stretchable semiconductors and electronic circuits preferred for some applications are flexible, in addition to being stretchable, and thus are capable of significant elongation, flexing, bending or other deformation along one or more axes. Further, stretchable semiconductors and electronic circuits of the present invention are adapted to a wide range of device configurations to provide fully flexible electronic and optoelectronic devices.
FILED Thursday, September 06, 2007
APPL NO 11/851182
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/9
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217412 Yuan et al.
FUNDED BY
Department of Energy (DOE)
Office of Fossil Energy and Carbon Management (FECM)
National Energy Technology Laboratory (NETL)
APPLICANT(S)
ASSIGNEE(S) Cree, Inc. (Goleta, California)
INVENTOR(S) Thomas Yuan (Ventura, California);  Bernd Keller (Santa Barbara, California);  James Ibbetson (Santa Barbara, California);  Eric Tarsa (Goleta, California);  Gerald Negley (Durham, North Carolina)
ABSTRACT An LED component comprising an array of LED chips mounted on a planar surface of a submount with the LED chips capable of emitting light in response to an electrical signal. The LED chips comprise respective groups emitting at different colors of light, with each of the groups interconnected in a series circuit. A lens is included over the LED chips. Other embodiments can comprise thermal spreading structures included integral to the submount and arranged to dissipate heat from the LED chips.
FILED Thursday, September 16, 2010
APPL NO 12/883979
ART UNIT 2892 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/98
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217596 Douglas et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Thomas Jefferson National Accelerator Facility (TJNAF)
Federally Funded Research and Development Center (FFRDC)
Operated by Jefferson Science Associates, LLC (JSA) at Newport News, VA
APPLICANT(S)
ASSIGNEE(S) Jefferson Science Associates, LLC (Newport News, Virginia)
INVENTOR(S) David R. Douglas (Newport News, Virginia);  Christopher D. Tennant (Williamsburg, Virginia)
ABSTRACT A method of avoiding CSR induced beam quality defects in free electron laser operation by a) controlling the rate of compression and b) using a novel means of integrating the compression with the remainder of the transport system: both are accomplished by means of dispersion modulation. A large dispersion is created in the penultimate dipole magnet of the compression region leading to rapid compression; this large dispersion is demagnified and dispersion suppression performed in a final small dipole. As a result, the bunch is short for only a small angular extent of the transport, and the resulting CSR excitation is small.
FILED Wednesday, March 18, 2009
APPL NO 12/381954
ART UNIT 2821 — Semiconductors/Memory
CURRENT CPC
Electric lamp and discharge devices: Systems
315/503
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218396 Holcomb et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) David E. Holcomb (Oak Ridge, Tennessee);  Roger A. Kisner (Knoxville, Tennessee)
ABSTRACT A level measurement system suitable for use in a high temperature and pressure environment to measure the level of coolant fluid within the environment, the system including a volume of coolant fluid located in a coolant region of the high temperature and pressure environment and having a level therein; an ultrasonic waveguide blade that is positioned within the desired coolant region of the high temperature and pressure environment; a magnetostrictive electrical assembly located within the high temperature and pressure environment and configured to operate in the environment and cooperate with the waveguide blade to launch and receive ultrasonic waves; and an external signal processing system located outside of the high temperature and pressure environment and configured for communicating with the electrical assembly located within the high temperature and pressure environment.
FILED Tuesday, March 16, 2010
APPL NO 12/724818
ART UNIT 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems
CURRENT CPC
Communications, electrical: Acoustic wave systems and devices
367/99
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218838 Karnowski et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) UT-Battelle, LLC (Oak Ridge, Tennessee)
INVENTOR(S) Thomas P. Karnowski (Knoxville, Tennessee);  Kenneth W. Tobin, Jr. (Harriman, Tennessee);  Vijaya Priya Muthusamy Govindasamy (Knoxville, Tennessee);  Edward Chaum (Memphis, Tennessee)
ABSTRACT A method for assigning a confidence metric for automated determination of optic disc location that includes analyzing a retinal image and determining at least two sets of coordinates locating an optic disc in the retinal image. The sets of coordinates can be determined using first and second image analysis techniques that are different from one another. An accuracy parameter can be calculated and compared to a primary risk cut-off value. A high confidence level can be assigned to the retinal image if the accuracy parameter is less than the primary risk cut-off value and a low confidence level can be assigned to the retinal image if the accuracy parameter is greater than the primary risk cut-off value. The primary risk cut-off value being selected to represent an acceptable risk of misdiagnosis of a disease having retinal manifestations by the automated technique.
FILED Monday, November 03, 2008
APPL NO 12/263876
ART UNIT 2826 — Semiconductors/Memory
CURRENT CPC
Image analysis
382/128
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08220067 Adams et al.
FUNDED BY
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S)
ASSIGNEE(S) Board of Regents of the Nevada System of Higher Education (Reno, Nevada)
INVENTOR(S) Jesse D. Adams (Reno, Nevada);  Todd A. Sulchek (Oakland, California);  Stuart C. Feigin (Reno, Nevada)
ABSTRACT A disclosed chemical detection system for detecting a target material, such as an explosive material, can include a cantilevered probe, a probe heater coupled to the cantilevered probe, and a piezoelectric element disposed on the cantilevered probe. The piezoelectric element can be configured as a detector and/or an actuator. Detection can include, for example, detecting a movement of the cantilevered probe or a property of the cantilevered probe. The movement or a change in the property of the cantilevered probe can occur, for example, by adsorption of the target material, desorption of the target material, reaction of the target material and/or phase change of the target material. Examples of detectable movements and properties include temperature shifts, impedance shifts, and resonant frequency shifts of the cantilevered probe. The overall chemical detection system can be incorporated, for example, into a handheld explosive material detection system.
FILED Monday, March 29, 2010
APPL NO 12/748788
ART UNIT 2881 — Optics
CURRENT CPC
Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM]
850/56
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 08215171 Smith et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Electrical, Communications and Cyber Systems (ECCS)
APPLICANT(S)
ASSIGNEE(S) University of South Florida (Tampa, Florida)
INVENTOR(S) Allan Smith (Chatham, Massachusetts);  Charity F. Smith, legal representative (Chatham, Massachusetts);  Venkat R. Bhethanabotla (Tampa, Florida);  Anthony J. Richardson (Palmetto, Florida)
ABSTRACT A ring electrode design that produces a uniform mass sensitivity distribution across a TSM device is presented. A new technique and apparatus to measure this mass sensitivity distribution is also presented. Novel electrode geometries on thickness shear mode (TSM) quartz resonators achieve radial uniformity of mass sensitivity, how receptive the device is to mass loadings, and high frequency stability across the active sensing area of the sensor device. The device allows for absolute mass measurement down to the nanogram level. Fabricated devices utilizing model predictions were tested using this apparatus, and good agreement between theory and experiment is found.
FILED Wednesday, August 26, 2009
APPL NO 12/547976
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/580
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08215834 Huang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Civil and Mechanical Systems (CMS)
APPLICANT(S)
ASSIGNEE(S) Board of Regents, The University of Texas System (Austin, Texas)
INVENTOR(S) Haiying Huang (Arlington, Texas);  Ayan Majumdar (San Jose, California)
ABSTRACT An optical fiber based polymer core sensor includes an optical fiber having a core and an end having a cured polymer core affixed to the core of the optical fiber. The cured polymer core extends outward from the end of the optical fiber and has a diameter approximately equal to the core of the optical fiber. Note the cured polymer core can be substantially cylindrical, tapered or geometrically shaped. The optical fiber based polymer core sensor can be used to measure a temperature, measure a strain, measure a distance, measure a refractive index, detect or measure an analyte, detect a toxin, detect a biological agent, monitor a chemical process, or a combination thereof.
FILED Saturday, September 05, 2009
APPL NO 12/554908
ART UNIT 2855 — Printing/Measuring and Testing
CURRENT CPC
Thermal measuring and testing
374/161
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216445 Anderson et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Marc A. Anderson (Madison, Wisconsin);  Kevin C. Leonard (Madison, Wisconsin)
ABSTRACT A nanoporous insulating oxide deionization device, method of manufacture and method of use thereof for deionizing a water supply (such as a hard water supply), for desalinating a salt water supply, and for treating a bacteria-containing water supply. The device contains two composite electrodes each constructed from a conductive backing electrode and a composite oxide layer being an insulating oxide or a non-insulating oxide and an intermediate porous layer. The composite layer being substantially free of mixed oxidation states and nanoporous and having a median pore diameter of 0.5-500 nanometers and average surface area of 300-600 m2/g. The composite layer made from a stable sol-gel suspension containing particles of the insulating oxide, the median primary particle diameter being 1-50 nanometers. The difference in zeta potential, at a pH in the range of 6-9, being sufficient to suitably remove alkaline and alkaline earth cations (such as Ca2+ and Na1+), various organic and other inorganic cations and organic and inorganic anions from water, preferably household hard water. One composite layer being constructed from a mixture of Al2O3, MgAl2O4 and/or Mg-doped Al2O3 particles, and the other composite layer being constructed from SiO2 or TiO2.
FILED Wednesday, October 31, 2007
APPL NO 11/932741
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Electrolysis: Processes, compositions used therein, and methods of preparing the compositions
25/701
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216537 Kouvetakis et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S)
ASSIGNEE(S) Arizona Board of Regents (Scottsdale, Arizona)
INVENTOR(S) John Kouvetakis (Mesa, Arizona);  Cole J. Ritter, III (Palmer Township, Pennsylvania);  Changwu Hu (Gilbert, Arizona);  Ignatius S. T. Tsong (Scottsdale, Arizona);  Andrew Chizmeshya (Chandler, Arizona)
ABSTRACT The present invention provides novel silicon-germanium hydride compounds, methods for their synthesis, methods for their deposition, and semiconductor structures made using the novel compounds.
FILED Tuesday, November 21, 2006
APPL NO 12/093279
ART UNIT 2891 — Semiconductors/Memory
CURRENT CPC
Chemistry of inorganic compounds
423/324
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217131 Edmiston
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) ABS Materials, Inc. (Wooster, Ohio)
INVENTOR(S) Paul L Edmiston (Wooster, Ohio)
ABSTRACT Disclosed is a method for extracting metal particulates for an aqueous solution using a sol-gel derived sorbent.
FILED Thursday, February 17, 2011
APPL NO 13/029771
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
528/35
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217169 Carpino et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
APPLICANT(S)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts)
INVENTOR(S) Louis A. Carpino (Amherst, Massachusetts);  Jusong Xia (Moore, South Carolina);  Chongwu Zhang (Dayton, New Jersey);  Calin Dan Sferdean (Riverview, Michigan)
ABSTRACT The present invention is directed to compounds of the formula:
or salts thereof or N-oxides and their use in peptide synthesis.
FILED Monday, October 11, 2010
APPL NO 12/901956
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Organic compounds
544/184
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218448 Cox, Jr. et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S)
ASSIGNEE(S) Blended Integrated Circuit Systems, LLC (St. Louis, Missouri)
INVENTOR(S) Jerome R. Cox, Jr. (St. Louis, Missouri);  Michael B. Grote (St. Louis, Missouri)
ABSTRACT The integrity of a control network for providing reliable communications between different entities is verified. Such a verified control network may be included in a device, system, or design library. The verification of a control network includes, but is not limited to: physically exercising the control network itself and/or its design via modeling, analysis, and/or applying or using other testing or design verification methodologies. For example, a Petri net model of the control network may be analyzed to verify that the control signals cannot be generated which could interfere with each other, that a deadlock condition cannot be reached, and that a control signal on an input port will result in a control signal on an output port, albeit possibly delayed.
FILED Thursday, August 26, 2010
APPL NO 12/869298
ART UNIT 2472 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/242
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218493 Mishra et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Arunesh Mishra (Mountain View, California);  Suman Banerjee (Madison, Wisconsin);  Vivek Shrivastava (Madison, Wisconsin);  Shravan Rayanchu (Madison, Wisconsin)
ABSTRACT A computer-implemented method for scheduling a packet for transmission in a wireless local area network can be used to account for hidden and/or exposed terminals. The method includes determining whether the packet is to be transmitted to a computing device through a wireless access point that is in conflict with at least one other computing device associated with a different access point. The method further includes determining whether there is a conflicting packet scheduled to be transmitted for any conflicting computing devices associated with a different access points and scheduling the packet for transmission based on any conflicting packets. The method yet further includes forwarding the packet to a wireless access point at the scheduled time.
FILED Tuesday, September 08, 2009
APPL NO 12/555452
ART UNIT 2471 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/329
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218895 Gleicher et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Michael Lee Gleicher (Madison, Wisconsin);  Feng Liu (Madison, Wisconsin)
ABSTRACT A retargeted image substantially retains the context of an original image while emphasizing the information content of a determined region of interest within the original image. Image regions surrounding the region of interest are warped without regard to preserving their information content and/or aspect ratios, while the region of interest is modified to preserve its aspect ratio and image content. The surrounding image regions can be warped to fit the resulting warped image regions into the available display space surrounding the unwarped region of interest. The surrounding image regions can be warped using one or more fisheye warping functions, which can be Cartesian or polar fisheye warping functions, and more specifically linear or linear-polynomial Cartesian fisheye warping functions, which are applied along each direction or axis of the region of interest. The image region on each side of the region of interest can be modified using one or more steps.
FILED Wednesday, September 27, 2006
APPL NO 11/535808
ART UNIT 2624 — Selective Visual Display Systems
CURRENT CPC
Image analysis
382/275
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 08215454 Portlock et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) United Technologies Corporation (Hartford, Connecticut)
INVENTOR(S) Lawrence E. Portlock (Bethany, Connecticut);  Michael E. McCune (Colchester, Connecticut);  Louis J. Dobek (Somers, Connecticut)
ABSTRACT A lubrication system includes an auxiliary lubricant tank 48, a supply conduit 58 extending from a source of lubricant 26 to the auxiliary lubricant tank. A reduced-G bypass line 108 branches from the conduit and enters the auxiliary tank at a first elevation E1. The system also includes an auxiliary tank discharge conduit 116, a portion of which resides within the tank. The resident portion has an opening 122 at least partially at a second elevation E2 higher than the first elevation.
FILED Wednesday, November 22, 2006
APPL NO 11/603664
ART UNIT 3657 — Material and Article Handling
CURRENT CPC
Lubrication
184/6.120
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216447 Kounaves
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) O.I. Corporation (College Station, Texas)
INVENTOR(S) Samuel P. Kounaves (Winchester, Massachusetts)
ABSTRACT The invention disclosed is a total organic carbon (TOC) analyzer comprised of an electrochemical cell comprising a diamond-film electrode doped with boron or other conductivity inducing material. The diamond-film electrode is the working electrode and carries out the oxidation of TOC to produce carbon dioxide. The apparatus further comprises sensors for detecting the carbon dioxide produced. Such sensors include but are not limited to a tunable diode laser and/or ion-selective electrode. The invention also discloses a method for measuring TOC in an aqueous solution using a total organic carbon analyzer.
FILED Monday, December 14, 2009
APPL NO 12/637393
ART UNIT 1759 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Electrolysis: Processes, compositions used therein, and methods of preparing the compositions
25/787
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217143 Kim et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) National Institute of Aerospace Associates (Hampton, Virginia);  The United States of America as represented by the Administration of NASA (Washington, District of Columbia)
INVENTOR(S) Jae-Woo Kim (Newport News, Virginia);  Sang H. Choi (Poquoson, Virginia);  Peter T. Lillehei (Yorktown, Virginia);  Sang-Hyon Chu (Newport News, Virginia);  Yeonjoon Park (Yorktown, Virginia);  Glen C. King (Yorktown, Virginia);  James R. Elliott, Jr. (Yorktown, Virginia)
ABSTRACT Metal nanoshells are fabricated by admixing an aqueous solution of metal ions with an aqueous solution of apoferritin protein molecules, followed by admixing an aqueous solution containing an excess of an oxidizing agent for the metal ions. The apoferritin molecules serve as bio-templates for the formation of metal nanoshells, which form on and are bonded to the inside walls of the hollow cores of the individual apoferritin molecules. Control of the number of metal atoms which enter the hollow core of each individual apoferritin molecule provides a hollow metal nonparticle, or nanoshell, instead of a solid spherical metal nanoparticle.
FILED Thursday, July 12, 2007
APPL NO 11/827567
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217480 Ting et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) California Institute of Technology (Pasadena, California)
INVENTOR(S) David Z. Ting (Arcadia, California);  Arezou Khoshakhlagh (Pasadena, California);  Alexander Soibel (South Pasadena, California);  Cory J. Hill (Chesterfield, Missouri);  Sarath D. Gunapala (Stevenson Ranch, California)
ABSTRACT A superlattice-based infrared absorber and the matching electron-blocking and hole-blocking unipolar barriers, absorbers and barriers with graded band gaps, high-performance infrared detectors, and methods of manufacturing such devices are provided herein. The infrared absorber material is made from a superlattice (periodic structure) where each period consists of two or more layers of InAs, InSb, InSbAs, or InGaAs. The layer widths and alloy compositions are chosen to yield the desired energy band gap, absorption strength, and strain balance for the particular application. Furthermore, the periodicity of the superlattice can be “chirped” (varied) to create a material with a graded or varying energy band gap. The superlattice based barrier infrared detectors described and demonstrated herein have spectral ranges covering the entire 3-5 micron atmospheric transmission window, excellent dark current characteristics operating at least 150K, high yield, and have the potential for high-operability, high-uniformity focal plane arrays.
FILED Wednesday, August 03, 2011
APPL NO 13/197588
ART UNIT 2893 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/431
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218013 Ellis et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S)
ASSIGNEE(S) Exelis, Inc (McLean, Virginia)
INVENTOR(S) Kenneth K. Ellis (Churubusco, Indiana);  Paul C. Griffith (Fort Wayne, Indiana)
ABSTRACT A star sensor includes (a) a scan mirror for scanning at least one star; (b) a detector array, coupled to the scan mirror, for detecting the one star; and (c) a processor, coupled to the detector array. The processor includes a first filter configured to reduce noise spikes in the detected one star, and provide a detection mask of filtered data. Also included is a second filter configured to reduce non-contiguous samples in the detection mask. A centroid calculator is included to determine a location of the one star, after the first and second filtering. The first filter includes a median filter, followed by an averaging filter, both configured to filter the one star in an along-scan direction of the scan mirror. The first filter includes another median filter, which is configured to filter the detected one star in the cross-scan direction of the scan mirror. An adder is included to subtract (a) output data from the other median filter from (b) output data from the averaging filter and provide filtered star data to the second filter.
FILED Tuesday, May 27, 2008
APPL NO 12/127105
ART UNIT 2443 — Computer Networks
CURRENT CPC
Television
348/169
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08219346 Zurbuchen et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Goddard Space Flight Center (GSFC)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) Thomas Zurbuchen (Ann Arbor, Michigan);  Steven Rogacki (Chelsea, Michigan)
ABSTRACT Various techniques are described for high resolution time measurement using a programmable device, such as a field programmable gate array (FPGA). The timing may be triggered by any event, depending on the applications of use. Once triggering has occurred, a START pulse begins propagating through the FPGA. The pulse is able to propagate through the FPGA in a staggered manner traversing multiple FPGA columns to maximize the amount of time delay that may be achieved while minimizing the overall array size, and thus minimizing the resource utilization, of the FPGA. The FPGA timing delay is calibrated by measuring for the linear and non-linear differences in delay time of each unit circuit forming the staggered delay line path for the timing circuit. The FPGA is able to achieve nanosecond and sub-nanosecond time resolutions.
FILED Thursday, June 16, 2011
APPL NO 13/162222
ART UNIT 2857 — Printing/Measuring and Testing
CURRENT CPC
Data processing: Measuring, calibrating, or testing
72/89
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Agriculture (USDA) 

US 08216551 Erf
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
National Institute of Food and Agriculture (NIFA)
APPLICANT(S)
ASSIGNEE(S) The Board of Trustees of the University of Arkansas (Little Rock, Arkansas)
INVENTOR(S) Gisela F. Erf (Fayetteville, Arkansas)
ABSTRACT Methods of evaluating the tissue response to an agent in birds are provided. Also disclosed are methods of monitoring exposure to agents in birds and methods of determining the efficacy of vaccines.
FILED Monday, May 18, 2009
APPL NO 12/467727
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217228 Dodo et al.
FUNDED BY
Department of Agriculture (USDA)
Agricultural Research Service (ARS)
Cooperative State Research, Education, and Extension Service (CSREES)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Hortense W. Dodo (Huntsville, Alabama);  Charles J. Arntzen (Ithaca, New York);  Olga Martha Viquez (Huntsville, Alabama);  Koffi N'da Konan (Huntsville, Alabama)
ABSTRACT An allergen-free transgenic peanut seed is produced by recombinant methods. Peanut plants are transformed with multiple copies of each of the allergen genes, or fragments thereof, to suppress gene expression and allergen protein production. Alternatively, peanut plants are transformed with peanut allergen antisense genes introduced into the peanut genome as antisense fragments, sense fragments, or combinations of both antisense and sense fragments. Peanut transgenes are under the control of the 35S promoter, or the promoter of the Ara h2 gene to produce antisense RNAs, sense RNAs, and double-stranded RNAs for suppressing allergen protein production in peanut plants. A full length genomic clone for allergen Ara h2 is isolated and sequenced. The ORF is 622 nucleotides long. The predicted encoded protein is 207 amino acids long and includes a putative transit peptide of 21 residues. One polyadenilation signal is identified at position 951. Six additional stop codons are observed. A promoter region was revealed containing a putative TATA box located at position −72. Homologous regions were identified between Ara h2, h6, and h7, and between Ara h3 and h4, and between Ara h1P41B and Ara h1P17. The homologous regions will be used for the screening of peanut genomic library to isolate all peanut allergen genes and for down-regulation and silencing of multiple peanut allergen genes.
FILED Thursday, April 29, 2010
APPL NO 12/770435
ART UNIT 1638 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Multicellular living organisms and unmodified parts thereof and related processes
8/286
VIEW PATENT @ USPTO:  Full Text   PDF 
US PP22845 Bliss et al.
FUNDED BY
Department of Agriculture (USDA)
APPLICANT(S)
ASSIGNEE(S) The Regents of the University of California (Oakland, California);  The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia)
INVENTOR(S) Fredrick A. Bliss (Davis, California);  Ali A. Almehdi (Davis, California);  Theodore M. Dejong (Davis, California);  Anne Gillen (Leland, Mississippi);  Craig A. Ledbetter (Clovis, California)
ABSTRACT The new ‘HBOK32’ rootstock, a hybrid between two peach parents, is useful as a commercial under-stock for peach and nectarine cultivars. The stock has been successfully propagated clonally by leafy cuttings and tissue culture. This rootstock imparts significant vigor control to the scion cultivar that is propagated on top of it. This rootstock produces very few root suckers, its anchorage is good and it is resistant to root-knot nematode. Utilization of adapted growth controlling rootstocks in commercial orchard situations reduces the height of the tree and the amount of wood pruned in the winter and summer, without compromising the quality of the fruit. This in turn increases the efficiency of various cultural operations such as pruning, thinning and harvesting by reducing the need for workers in the field to use tall ladders when carrying out these operations.
FILED Thursday, December 17, 2009
APPL NO 12/653856
ART UNIT 1661 — Plants
CURRENT CPC
Plants
PLT/194
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Commerce (DOC) 

US 08216526 Locascio et al.
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) The United States of America, as represented by the Secretary of Commerce, The National Institute of Standards and Technology (Washington, District of Columbia)
INVENTOR(S) Laurie E. Locascio (North Potomac, Maryland);  Francisco Javier Atencia-Fernandez (Bethesda, Maryland)
ABSTRACT A microfluidic device is described, capable of generating multiple spatial chemical gradients simultaneously inside a microfluidic chamber. The chemical gradients are generated by diffusion, without convection, and can either be maintained constant over long time periods, or modified dynamically. A representative device is described with a circular chamber in which diffusion occurs, with three access ports for the delivery and removal of solutes. A gradient typically forms in minutes, and can be maintained constant indefinitely. Gradients overlapping with different spatial location, and a controlled rotation of a gradient formed by diffusion are demonstrated. The device can also be used to evaluate chemotactic responses of bacteria or other microorganisms in the absence of convective flow.
FILED Wednesday, March 11, 2009
APPL NO 12/401900
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/503
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216811 Donnelly et al.
FUNDED BY
Department of Commerce (DOC)
APPLICANT(S)
ASSIGNEE(S) Danisco US Inc. (Palo Alto, California)
INVENTOR(S) Mark Donnelly (Warrensville, Illinois);  William H. Eschenfeldt (St. Charles, Illinois);  Jonathan Trent (La Silva Beach, California)
ABSTRACT Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described.
FILED Friday, March 04, 2011
APPL NO 13/041176
ART UNIT 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/132
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217081 Antonucci
FUNDED BY
Department of Commerce (DOC)
National Institute of Standards and Technology (NIST)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Secretary of Commerce, The National Institute of Standards and Technology (Washington, District of Columbia)
INVENTOR(S) Joseph M. Antonucci (Kensington, Maryland)
ABSTRACT A polymerizable biomedical composition includes a quaternary ammonium group bonded at its quaternary sites to respective groups R1, R2, R3, and R4. R1 and R2 each include a vinyl moiety such that the composition is at least bi-functional with respect to polymerization.
FILED Monday, December 28, 2009
APPL NO 12/647661
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/642
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 08216969 Lombardi
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) John L. Lombardi (Tucson, Arizona)
ABSTRACT A pathogen-resistant fabric comprising one or more photocatalysts capable of generating singlet oxygen from ambient air. The pathogen-resistant fabric may optionally include one or more singlet oxygen traps.
FILED Tuesday, March 29, 2011
APPL NO 13/075051
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/438
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217131 Edmiston
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S)
ASSIGNEE(S) ABS Materials, Inc. (Wooster, Ohio)
INVENTOR(S) Paul L Edmiston (Wooster, Ohio)
ABSTRACT Disclosed is a method for extracting metal particulates for an aqueous solution using a sol-gel derived sorbent.
FILED Thursday, February 17, 2011
APPL NO 13/029771
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
528/35
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218448 Cox, Jr. et al.
FUNDED BY
National Science Foundation (NSF)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S)
ASSIGNEE(S) Blended Integrated Circuit Systems, LLC (St. Louis, Missouri)
INVENTOR(S) Jerome R. Cox, Jr. (St. Louis, Missouri);  Michael B. Grote (St. Louis, Missouri)
ABSTRACT The integrity of a control network for providing reliable communications between different entities is verified. Such a verified control network may be included in a device, system, or design library. The verification of a control network includes, but is not limited to: physically exercising the control network itself and/or its design via modeling, analysis, and/or applying or using other testing or design verification methodologies. For example, a Petri net model of the control network may be analyzed to verify that the control signals cannot be generated which could interfere with each other, that a deadlock condition cannot be reached, and that a control signal on an input port will result in a control signal on an output port, albeit possibly delayed.
FILED Thursday, August 26, 2010
APPL NO 12/869298
ART UNIT 2472 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/242
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Homeland Security (DHS) 

US 08217375 Keegan et al.
FUNDED BY
Department of Homeland Security (DHS)
APPLICANT(S)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Heather L. Keegan (Goffstown, New Hampshire);  Robert C. Guyer (Beverly, Massachusetts);  William T. Fielder (Boston, Massachusetts);  Donald K. Smith (Rye, New Hampshire)
ABSTRACT In an integrated gimbal and High-Powered Multiband Laser (HPMBL) for use in an infrared countermeasure apparatus in a pod mounted on an aircraft, the improvement comprises an optical bench that connects the optical path between side-by-side mounted gimbal and high power laser; and a kinematic mounting system that prevents optical bench bending.
FILED Friday, August 08, 2008
APPL NO 12/228032
ART UNIT 2881 — Optics
CURRENT CPC
Radiant energy
250/522.100
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 08216594 Ko et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
Fogarty International Center (FIC)
National Heart, Lung, and Blood Institute (NHLBI)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S)
ASSIGNEE(S) The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia);  The Regents of the University of California (Oakland, California);  Cornell Research Foundation, Inc. (Ithaca, New York);  Fundação Oswaldo Cruz-Fiocruz (Rio de Janeiro, Brazil)
INVENTOR(S) Albert I. Ko (Bahia, Brazil);  Mitermayer Galvão Reis (Bahia, Brazil);  Julio Henrique Rosa Croda (Bahia, Brazil);  Isadora Cristina Siqueira (Bahia, Brazil);  David A. Haake (Los Angeles, California);  James Matsunaga (Los Angeles, California);  Lee W. Riley (Berkeley, California);  Michele Barocchi (Florence, Italy);  Tracy Ann Young (Oakland, California)
ABSTRACT The invention relates to three isolated DNA molecules that encode for proteins, BigL1, BigL2 and BigL3, in the Leptospira sp bacterium which have repetitive Bacterial-Ig-like (Big) domains and their use in diagnostic, therapeutic and vaccine applications. According to the present invention, the isolated molecules encoding for BigL1, BigL2 and BigL3 proteins are used for the diagnosis and prevention of infection with Leptospira species that are capable of producing disease in humans and other mammals, including those of veterinary importance.
FILED Thursday, January 26, 2012
APPL NO 13/359354
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/269.100
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 08216797 Schwoebel et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) Eric Schwoebel (Woburn, Massachusetts);  James Harper (Jamaica Plain, Massachusetts);  Martha S. Petrovick (Barre, Massachusetts);  Frances Nargi (Littleton, Massachusetts);  Mark Hollis (Concord, Massachusetts);  Bernadette Johnson (Hollis, New Hampshire);  Joseph Lacirignola (Beverly, Massachusetts);  Richard Mathews (Chelmsford, Massachusetts);  Kristine Hogan (Danvers, Massachusetts);  Trina Vian (Groton, Massachusetts);  Allan Heff (Newton, Massachusetts);  Mark Hennessy (Falls Church, Virginia);  Songeeta Palchaudhuri (Somerville, Massachusetts);  Todd Rider (Littleton, Massachusetts)
ABSTRACT The invention described herein provides methods for the detection of target particles, such as pathogens, soluble antigens, nucleic acids, toxins, chemicals, plant pathogens, blood borne pathogens, bacteria, viruses and the like. Also described is an emittor cell comprising a receptor, wherein the receptor can be an antibody or an Fc receptor, and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more receptors on the emittor cell. Also provided are optoelectronic sensor devices for detecting a target particle in a sample, including in a plurality of samples.
FILED Thursday, November 30, 2006
APPL NO 12/085495
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.200
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 08219848 Branson et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Michael John Branson (Rochester, Minnesota);  Frederick Douglis (Basking Ridge, New Jersey);  Bradley William Fawcett (Byron, Minnesota);  Zhen Liu (Tarrytown, New York);  Bin Rong (Melbourne, Australia);  Fan Ye (Yorktown Heights, New York)
ABSTRACT A failure recovery framework to be used in cooperative data stream processing is provided that can be used in a large-scale stream data analysis environment. Failure recovery supports a plurality of independent distributed sites, each having its own local administration and goals. The distributed sites cooperate in an inter-site back-up mechanism to provide for system recovery from a variety of failures within the system. Failure recovery is both automatic and timely through cooperation among sites. Back-up sites associated with a given primary site are identified. These sites are used to identify failures within the primary site including failures of applications running on the nodes of the primary site. The failed applications are reinstated on one or more nodes within the back-up sites using job management instances local to the back-up sites in combination with previously stored state information and data values for the failed applications. In additions to inter-site mechanisms, each one of the plurality of sites employs an intra-site back-up mechanism to handle failure recoveries within the site.
FILED Tuesday, April 10, 2007
APPL NO 11/733724
ART UNIT 2114 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/3
VIEW PATENT @ USPTO:  Full Text   PDF 

U.S. State Government 

US D663352 Park
FUNDED BY
U.S. State Government
State of Florida
APPLICANT(S)
ASSIGNEE(S) Numark Industries, L.P., a Limited Partnership of the state of Florida (Cumberland, Rhode Island)
INVENTOR(S) Jae Jun Park (Lincoln, Rhode Island)
ABSTRACT
FILED Monday, May 17, 2010
APPL NO 29/361851
ART UNIT 2916 — Design
CURRENT CPC
Musical instruments
D17/22
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

US 08215848 Chan et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Eric Yuen-Jun Chan (Mercer Island, Washington);  Alex A. Kazemi (Altadena, California);  Dennis G. Koshniz (Bellevue, Washington)
ABSTRACT A method for providing an improved interconnection between an optical fiber and an optical package is described. The method includes inserting an end of the fiber through a feed through tube and into a main body of the optical package, a portion of the fiber proximate the end being metalized, attaching the metalized portion of the fiber within the main body of the optical package, a portion of the metalized fiber remaining within the feed through tube, inserting a stopping device into the feed through tube, melting solder within the feed through tube, in an area between the stopping device and the main body of the optical device, the area containing metalized fiber, compressing the melted solder using the stopping device, removing the stopping device from the feed through tube after the solder has solidified, and attaching a jacket associated with the optical fiber within the feed through tube.
FILED Tuesday, May 12, 2009
APPL NO 12/464585
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/91
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08216543 Chen et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Inframat Corporation (Farmington, Connecticut);  University of Houston (Houston, Texas)
INVENTOR(S) Huimin Chen (Willington, Connecticut);  Dennis A. Clifford (Houston, Texas);  Meidong Wang (Amherst, New York);  T. Danny Xiao (Willington, Connecticut)
ABSTRACT Methods of making unique water treatment compositions are provided. In one embodiment, a method of making a doped metal oxide or hydroxide for treating water comprises: disposing a metal precursor solution and a dopant precursor solution in a reaction vessel comprising water to form a slurry; and precipitating the doped metal oxide or hydroxide from the slurry.
FILED Thursday, June 14, 2007
APPL NO 11/763048
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry of inorganic compounds
423/608
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08217368 Meyers et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S)
INVENTOR(S) Ronald Everett Meyers (Columbia, Maryland);  David Lawrence Rosen (Rockville, Maryland)
ABSTRACT A method and system for investigating properties of an object comprising: a transmitter, including a radiation source, the transmitter providing incident radiation having a plurality of predetermined polarization states; the incident radiation illuminating an object and thereby causing the object to emit photoemission; a receiver, receiving photoemission from the object when the object is illuminated by the incident radiation, the receiver including a detector, the detector providing photoemission intensity data; and signal processing circuitry, in electrical communication with the detector, the signal processing circuitry determining three-dimensional information relating to the object from the photoemission intensity data for each of the plurality of incident polarization states.
FILED Friday, November 05, 2010
APPL NO 12/940204
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/459.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08218703 Pratt et al.
FUNDED BY
APPLICANT(S)
ASSIGNEE(S) Battelle Memorial Institute (Richmond, Washington)
INVENTOR(S) Richard M. Pratt (Richland, Washington);  Steven B. Thompson (Richland, Washington)
ABSTRACT In one aspect, a wireless communication device includes an antenna configured to receive electromagnetic energy corresponding to a wireless communication signal outputted using an interrogator and to output electrical energy corresponding to the received electromagnetic energy, communication circuitry coupled with the antenna and configured to sample the electrical energy to process the wireless communication signal, synchronization circuitry coupled with the antenna and the communication circuitry and configured to generate a clock signal to control sampling of the electrical energy using the communication circuitry, wherein the synchronization circuitry is configured to generate a plurality of transitions within the clock signal responsive to a plurality of transitions of the electrical energy during a first data period and wherein the synchronization circuitry is configured to generate a plurality of transitions within the clock signal during a second data period including generating at least one of the transitions independent of transitions of the electrical energy.
FILED Thursday, December 03, 2009
APPL NO 12/630764
ART UNIT 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Pulse or digital communications
375/360
VIEW PATENT @ USPTO:  Full Text   PDF 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, July 10, 2012.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.

HOW DO I FIND A SPECIFIC PATENT ON A PAGE?

You can use the Command F or Control F to find a specific patent you are interested in.

HOW DO I GET HERE?

You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

You can also reach this page using the weekly page link that looks like this:

https://wayfinder.digital/fedinvent/patents-2012/fedinvent-patents-20120710.html

Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.

Download a copy of the How To Use This Page

HAVE MORE QUESTIONS?

info@wayfinder.digital