FedInvent™ Patents

Patent Details for Tuesday, March 12, 2013 

This page was updated on Monday, March 27, 2023 at 03:45 AM GMT

Department of Health and Human Services (HHS) 

US 08393785 De Bruyker et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Dirk De Bruyker (San Jose, California);  Francisco E. Torres (San Jose, California);  Michal V. Wolkin (Los Altos Hills, California);  Gregory B. Anderson (Emerald Hills, California);  Eugene M. Chow (Fremont, California)
ASSIGNEE(S) Palo Alto Research Center Incorporated (Palo Alto, California)
INVENTOR(S) Dirk De Bruyker (San Jose, California);  Francisco E. Torres (San Jose, California);  Michal V. Wolkin (Los Altos Hills, California);  Gregory B. Anderson (Emerald Hills, California);  Eugene M. Chow (Fremont, California)
ABSTRACT A nanocalorimeter includes a merging layer having, a drop placement area for holding drops to be merged and a thermal equilibration area. A measurement layer includes a substrate, and a temperature probe on the substrate, wherein the temperature probe extends out of the surface of the substrate to come into operative contact with the thermal equilibration area when the measurement layer is placed in operative association with the merging layer. The nanocalorimeter is configured to have the merging layer and the measurement layer non-integrated, making the measurement layer reusable.
FILED Friday, May 15, 2009
APPL NO 12/467072
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Thermal measuring and testing
374/31
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394354 Paige et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Mental Health (NIMH)
APPLICANT(S) Lisa A. Paige (Hillsborough, North Carolina);  Matthew W. Mitchell (Durham, North Carolina);  Anne Evans (Durham, North Carolina);  Don Harvan (Durham, North Carolina);  David Carl Steffens (Durham, North Carolina);  K. Ranga R. Krishnan (Chapel Hill, North Carolina);  Rima Kaddurah-Daouk (Belmont, Massachusetts)
ASSIGNEE(S) Metabolon, Inc. (Durham, North Carolina);  Duke University (Durham, North Carolina)
INVENTOR(S) Lisa A. Paige (Hillsborough, North Carolina);  Matthew W. Mitchell (Durham, North Carolina);  Anne Evans (Durham, North Carolina);  Don Harvan (Durham, North Carolina);  David Carl Steffens (Durham, North Carolina);  K. Ranga R. Krishnan (Chapel Hill, North Carolina);  Rima Kaddurah-Daouk (Belmont, Massachusetts)
ABSTRACT The present invention provides various biomarkers of depression. The present invention also provides various methods of using the biomarkers, including methods for diagnosis of depression, methods of determining predisposition to depression, methods of monitoring progression/regression of depression, methods of assessing efficacy of compositions for treating depression, methods of screening compositions for activity in modulating biomarkers of depression, methods of treating depression, as well as other methods based on biomarkers of depression.
FILED Tuesday, May 08, 2007
APPL NO 12/300000
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/9.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394373 Ginsburg et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) David Ginsburg (Ann Arbor, Michigan);  Gallia Levy (Ann Arbor, Michigan);  Han-Mou Tsai (Manhasset, New York)
ASSIGNEE(S) The Regents of the University of Michigan (Ann Arbor, Michigan)
INVENTOR(S) David Ginsburg (Ann Arbor, Michigan);  Gallia Levy (Ann Arbor, Michigan);  Han-Mou Tsai (Manhasset, New York)
ABSTRACT The present invention relates to a disintegrin and metalloproteinase containing thrombospondin 1-like domains (ADAMTS) and in particular to a novel ADAMTS13 protease and to nucleic acids encoding ADAMTS13 proteases. The present invention encompasses both native and recombinant wild-type forms of ADAMTS13, as well as mutant and variant forms including fragments, some of which posses altered characteristics relative to the wild-type ADAMTS13. The present invention also relates to methods of using ADAMTS13, including for treatment of TTP. The present invention also relates to methods for screening for the presence of TTP. The present invention further relates to methods for developing anticoagulant drugs based upon ADAMTS13.
FILED Monday, April 13, 2009
APPL NO 12/422803
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/94.670
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394375 Martin
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Paul Taylor Martin (Bexley, Ohio)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Paul Taylor Martin (Bexley, Ohio)
ABSTRACT Phage peptide display technology was used to identify peptides that bind specifically to the amyloid form of the Aβ1-40 peptide. Peptides with similar structural features and bind to the amyloid form of Aβ1-40 but not to monomeric Aβ1-40, are provided. Such peptides are useful as carrier molecules to deliver therapeutic and diagnostic reagents to amyloid plaques.
FILED Thursday, April 22, 2010
APPL NO 12/765740
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/130.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394380 Manucharyan et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Karen Manucharyan (Coyoacan, Mexico);  Gohar Gevorgyan (Coyoacan, Mexico)
ASSIGNEE(S) Primex Clinical Laboratories, Inc. (Van Nuys, California)
INVENTOR(S) Karen Manucharyan (Coyoacan, Mexico);  Gohar Gevorgyan (Coyoacan, Mexico)
ABSTRACT The present invention concerns methods and compositions of use for treatment of Alzheimer's Disease (AD). In certain embodiments, the methods concern preparation of phage-display single chain antibody libraries and screening against amyloid-beta (Aβ) protein or peptide. Anti-Aβ antibodies are selected and sequenced. In certain embodiments, synthetic Aβ binding peptides are designed and prepared, using portions of the anti-Aβ antibody sequences. The antibodies and peptides are of use for treatment of AD or for treatment of individuals at risk of developing AD. Compositions comprising anti-Aβ antibodies or Aβ binding peptides are also disclosed.
FILED Friday, November 12, 2010
APPL NO 12/945669
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/135.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394387 Leppla et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Stephen H. Leppla (Bethesda, Maryland);  Mary Jo Rosovitz (Germantown, Maryland);  John B. Robbins (New York, New York);  Rachel Schneerson (Bethesda, Maryland);  S. Dana Hsu (Bethesda, Maryland);  Joseph Shiloach (Rockville, Maryland);  Delia M. Ramirez (Bethesda, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Stephen H. Leppla (Bethesda, Maryland);  Mary Jo Rosovitz (Germantown, Maryland);  John B. Robbins (New York, New York);  Rachel Schneerson (Bethesda, Maryland);  S. Dana Hsu (Bethesda, Maryland);  Joseph Shiloach (Rockville, Maryland);  Delia M. Ramirez (Bethesda, Maryland)
ABSTRACT The invention relates to improved methods of producing and recovering sporulation-deficient B. anthracis mutant stains, and for producing and recovering recombinant B. anthracis protective antigen (PA), especially modified PA which is protease resistant, and to methods of using of these PAs or nucleic acids encoding these PAs for eliciting an immunogenic response in humans, including responses which provide protection against, or reduce the severity of, B. anthracis bacterial infections and which are useful to prevent and/or treat illnesses caused by B. anthracis, such as inhalation anthrax, cutaneous anthrax and gastrointestinal anthrax.
FILED Tuesday, July 31, 2007
APPL NO 11/831860
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/246.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394388 Jacobs, Jr. et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) William R. Jacobs, Jr. (Pelham, New York);  Steven A. Porcelli (Bronx, New York);  Volker Briken (Burtonsville, Maryland);  Miriam Braunstein (Chapel Hill, North Carolina)
ASSIGNEE(S) Albert Einstein College of Medicine of Yeshiva University (Bronx, New York)
INVENTOR(S) William R. Jacobs, Jr. (Pelham, New York);  Steven A. Porcelli (Bronx, New York);  Volker Briken (Burtonsville, Maryland);  Miriam Braunstein (Chapel Hill, North Carolina)
ABSTRACT Provided are recombinant mycobacteria having a mutation in an nlaA gene or in a nuoG gene. Also provided are isolated and purified nlaA proteins and nuoG proteins from a mycobacterium. Additionally provided are isolated and purified nucleic acids comprising a recombinant nlaA gene or a recombinant nuoG gene. Further provided are methods of inducing an immune response in a mammal and methods of making a recombinant mycobacterium using the nlaA gene or the nuoG gene.
FILED Thursday, January 12, 2006
APPL NO 11/794506
ART UNIT 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/248.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394391 Bae et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) You Han Bae (Salt Lake City, Utah);  Eun Seong Lee (Salt Lake City, Utah);  Dongin Kim (Salt Lake City, Utah);  Yu Seok Youn (Salt Lake City, Utah);  Kyung Taek Oh (Salt Lake City, Utah)
ASSIGNEE(S) University of Utah Research Foundation (Salt Lake City, Utah)
INVENTOR(S) You Han Bae (Salt Lake City, Utah);  Eun Seong Lee (Salt Lake City, Utah);  Dongin Kim (Salt Lake City, Utah);  Yu Seok Youn (Salt Lake City, Utah);  Kyung Taek Oh (Salt Lake City, Utah)
ABSTRACT A drug delivery vehicle for targeted delivery of a drug mimics viral properties of size, capsid-like protein capsule, cell-specific entry, toxin release, destruction of infected cells, and migration to neighboring cells. This vehicle, termed a virogel, contains a hydrophobic polymeric core, a hydrophilic inner shell, a hydrophilic outer shell, and a ligand. An illustrative drug-loaded virogel includes poly(L-histidine-co-phenylalanine) as the core, doxorubicin loaded in the core, polyethylene glycol as the inner shell, bovine serum albumin as the outer shell, and folic acid as the ligand.
FILED Friday, August 31, 2007
APPL NO 11/897979
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/400
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394411 Roberts et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Jeff Roberts (Rockville, Maryland);  Douglas R. Lowy (Bethesda, Maryland);  John T. Schiller (Kensington, Maryland)
ASSIGNEE(S) The United States of America as represented by the Secretary, Dept. of Health and Human Services National Institutes of Health (Washington, District of Columbia)
INVENTOR(S) Jeff Roberts (Rockville, Maryland);  Douglas R. Lowy (Bethesda, Maryland);  John T. Schiller (Kensington, Maryland)
ABSTRACT Disclosed herein are methods of detecting tumors, monitoring cancer therapy, and selectively inhibiting the proliferation and/or killing of cancer cells utilizing a papilloma pseudovirus or a papilloma virus-like particle (VLP).
FILED Thursday, May 01, 2008
APPL NO 12/598684
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
424/489
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394580 Riggins et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Gregory Riggins (Baltimore, Maryland);  Janete Cerutti (Sao Paolo, Brazil)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Gregory Riggins (Baltimore, Maryland);  Janete Cerutti (Sao Paolo, Brazil)
ABSTRACT This invention relates, e.g., to a method for detecting the presence of lymph node metastases in a subject having papillary thyroid carcinoma (PTC), comprising measuring in a sample from the subject the amount of expression (e.g., the amount of protein, or the amount of mRNA encoding the protein) of one or more of the following proteins: (a) LIMD2, and/or (b) PTPRC, and/or (c) LTB, and/or (d) CD48, and/or (e) ABCC3, wherein a significant amount of over-expression of one or more of protein(s) (a)-(e), compared to the baseline value, indicates that lymph node metastases are likely to be present in the subject.
FILED Monday, August 18, 2008
APPL NO 12/222876
ART UNIT 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/4
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394583 Monson
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Nancy Monson (Ovilla, Texas)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Nancy Monson (Ovilla, Texas)
ABSTRACT The present invention provides for the diagnosis and prediction of multiple sclerosis (MS) in subject utilizing a unique a codon signature in VH4 expressing B cells that has now been associated with MS and not with any other autoimmune disease.
FILED Friday, July 24, 2009
APPL NO 12/509093
ART UNIT 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394584 Timp et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Gregory Timp (South Bend, Indiana);  Winston Timp (Baltimore, Maryland);  Andrew Feinberg (Baltimore, Maryland);  Utkur Mirsaidov (Urbana, Illinois)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois);  The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Gregory Timp (South Bend, Indiana);  Winston Timp (Baltimore, Maryland);  Andrew Feinberg (Baltimore, Maryland);  Utkur Mirsaidov (Urbana, Illinois)
ABSTRACT Provided are methods for detecting, characterizing or separating DNA based on methylation. Heterogeneous DNA populations are separated based on DNA methylation by providing a membrane having a nanopore through which an electric field is applied. DNA of interest is introduced, and for a given threshold voltage across the nanopore, only DNA having a methylation parameter of interest may transit the pore, thereby facilitating detection, characterization, or separation of DNA based on methylation. The methods are optionally used to detect a disease state that is associated with DNA methylation including, but not limited to, cancer.
FILED Friday, December 18, 2009
APPL NO 13/133300
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394588 Tuschl et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
National Institute of Mental Health (NIMH)
APPLICANT(S) Thomas Tuschl (Brooklyn, New York);  John Pena (New York, New York);  Cherin Sohn (Rego Park, New York);  Sara Hakim (New York, New York);  Janos Ludwig (Bonn-Venusberg, Germany);  Pavol Cekan (New York, New York)
ASSIGNEE(S) The Rockefeller University (New York, New York)
INVENTOR(S) Thomas Tuschl (Brooklyn, New York);  John Pena (New York, New York);  Cherin Sohn (Rego Park, New York);  Sara Hakim (New York, New York);  Janos Ludwig (Bonn-Venusberg, Germany);  Pavol Cekan (New York, New York)
ABSTRACT In one aspect, the invention relates to a method for fixing a short nucleic acid in a biological sample. In another aspect, the invention relates to a method for detecting a target short nucleic acid in a biological sample. The method includes contacting the biological sample with an aldehyde-containing fixative, and subsequently contacting the sample with a water-soluble carbodiimide. In a further aspect, the invention relates to a kit for fixing a short nucleic acid in a biological sample. The kit includes a support substrate for holding the sample; an aldehyde-containing fixative; and a water-soluble carbodiimide.
FILED Wednesday, March 10, 2010
APPL NO 12/721550
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394589 Siddique et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Teepu Siddique (Wilmette, Illinois);  Han-Xiang Deng (Chicago, Illinois);  Jianhua Yan (Naperville, Illinois)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Teepu Siddique (Wilmette, Illinois);  Han-Xiang Deng (Chicago, Illinois);  Jianhua Yan (Naperville, Illinois)
ABSTRACT The present invention provides methods, kits, and compositions for detecting mutations in transient receptor potential cation channel, subfamily V, member 4 (TRPV4). In particular, mutations are detected in TRPV4 to detect diseases such as scapuloperoneal spinal muscular atrophy (SPSMA) and hereditary motor and sensory neuropathy type IIC (HMSN IIC) or Charcot-Marie-Tooth disease type 2C (CMT2C).
FILED Tuesday, December 21, 2010
APPL NO 12/974209
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394590 Kwong et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Gabriel A. Kwong (Alhambra, California);  Caius G. Radu (Los Angeles, California);  Owen Witte (Sherman Oaks, California);  James R. Heath (South Pasadena, California);  Antoni Ribas (Los Angeles, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California);  University of California (Oakland, California)
INVENTOR(S) Gabriel A. Kwong (Alhambra, California);  Caius G. Radu (Los Angeles, California);  Owen Witte (Sherman Oaks, California);  James R. Heath (South Pasadena, California);  Antoni Ribas (Los Angeles, California)
ABSTRACT Polynucleotide-encoded capture agents for target detection and in particular modular polynucleotide-capture agents comprising a target binding component, a scaffold component and an encoding component formed by standardized molecular units that can be coupled and decoupled in a controlled fashion, and related compositions methods and systems.
FILED Friday, October 08, 2010
APPL NO 12/901151
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.120
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394592 El-Zein et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of Environmental Health Sciences (NIEHS)
APPLICANT(S) Randa A. El-Zein (League City, Texas);  Matthew B. Schabath (Houston, Texas);  Carol J. Etzel (Houston, Texas);  Mirtha S. Lopez (Porter, Texas);  Margaret R. Spitz (Houston, Texas)
ASSIGNEE(S) The Board of Regents of the University of Texas System (Austin, Texas)
INVENTOR(S) Randa A. El-Zein (League City, Texas);  Matthew B. Schabath (Houston, Texas);  Carol J. Etzel (Houston, Texas);  Mirtha S. Lopez (Porter, Texas);  Margaret R. Spitz (Houston, Texas)
ABSTRACT The present invention demonstrates the differential sensitivity of PBLs from lung cancer patients and healthy controls to NNK-induced genetic damage. The data provide convincing evidence that the preferred CBMN assay is a robust test for detection of this sensitivity and yields results that are a good predictor of, for example, lung cancer risk. The simplicity, rapidity, and sensitivity of the CBMN test make it a valuable tool for screening and, for example, prioritizing potential cases for early detection of the disease.
FILED Monday, June 11, 2007
APPL NO 12/304298
ART UNIT 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.140
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394593 Robinson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Richard T. Robinson (Milwaukee, Wisconsin);  Andrea M. Cooper (Saranac Lake, New York)
ASSIGNEE(S) Trudeau Institute (Saranac Lake, New York)
INVENTOR(S) Richard T. Robinson (Milwaukee, Wisconsin);  Andrea M. Cooper (Saranac Lake, New York)
ABSTRACT The present invention describes compositions for both diagnostic and therapeutic applications. In one embodiment, the present invention contemplates a vaccine formulation comprising an antigen and IL12Rβ1 isoform 2. In some embodiments, this invention relates to a method of quantifying the ratio of IL12Rβ1 transcript and a splice variant thereof in a sample, including but not limited to at the cDNA level. In other embodiments, this invention relates to a method of augmenting an immune response by administering, inhibiting and/or inducing IL12Rβ1 isoform 2.
FILED Monday, February 07, 2011
APPL NO 13/022224
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.170
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394598 Bardelli et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Alberto Bardelli (Baltimore, Maryland);  Will Parsons (Ellicott City, Maryland);  Victor Velculescu (Dayton, Maryland);  Kenneth W. Kinzler (Bel Air, Maryland);  Bert Vogelstein (Baltimore, Maryland)
ASSIGNEE(S) The Johns Hopkins University (Baltimore, Maryland)
INVENTOR(S) Alberto Bardelli (Baltimore, Maryland);  Will Parsons (Ellicott City, Maryland);  Victor Velculescu (Dayton, Maryland);  Kenneth W. Kinzler (Bel Air, Maryland);  Bert Vogelstein (Baltimore, Maryland)
ABSTRACT Protein kinases are important signaling molecules involved in tumorigenesis. Mutational analysis of the human tyrosine kinase gene family (98 genes) identified somatic alterations in -20% of colorectal cancers, with the majority of mutations occurring in NTRK3, FES, GUCY2F and a previously uncharacterized tyrosine kinase gene called MCCK/MLK4. Most alterations were in conserved residues affecting key regions of the kinase domain. These data represent a paradigm for the unbiased analysis of signal transducing genes in cancer and provide useful targets for therapeutic intervention.
FILED Monday, February 15, 2010
APPL NO 12/705760
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.230
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394600 Castro
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S) Arnold R. Castro (Atlanta, Georgia)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Department of Health and Human Services, Centers for Disease Control and Prevention (Washington, District of Columbia)
INVENTOR(S) Arnold R. Castro (Atlanta, Georgia)
ABSTRACT Compositions, methods and devices for the detection of anti-lipoidal antibodies and the diagnosis of disease, for example, syphilis, are described. In particular, a method for immobilizing a lipoidal antigen, comprising cardiolipin, lecithin, and cholesterol, on a solid support (such as a nitrocellulose membrane) is described. The ability to immobilize a lipoidal antigen on a membrane satisfies a long-felt need for a membrane-based assay for the detection of anti-lipoidal antibodies. Also described are immunoassay devices for concurrently performing treponemal and non-treponemal tests for syphilis.
FILED Friday, March 23, 2012
APPL NO 13/429183
ART UNIT 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.360
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394601 Klein et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Jon B. Klein (Louisville, Kentucky);  Michael Merchant (Louisville, Kentucky);  Grzegorz Boratyn (Louisville, Kentucky)
ASSIGNEE(S) University of Louisville Research Foundation, Inc. (Louisville, Kentucky)
INVENTOR(S) Jon B. Klein (Louisville, Kentucky);  Michael Merchant (Louisville, Kentucky);  Grzegorz Boratyn (Louisville, Kentucky)
ABSTRACT Methods and kits are provided for diagnosing a kidney disease, or the risk thereof, in a subject. The methods include determining an amount of at least one peptide biomarker disclosed herein in a biological sample from the subject and comparing the amount of the at least one peptide in the sample with a control level, wherein if the amount determined is different than the control level, the subject is diagnosed as having, or at an increased risk of developing, the kidney disease.
FILED Friday, September 16, 2011
APPL NO 13/234756
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/7.920
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394605 Wang et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Jiangyun Wang (Beijing, China PRC);  Peter G. Schultz (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Jiangyun Wang (Beijing, China PRC);  Peter G. Schultz (La Jolla, California)
ABSTRACT The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetase that can incorporate the unnatural amino acid phenylselenocysteine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal aminoacyl-tRNA synthetases, polynucleotides encoding the novel sythetases molecules, methods for identifying and making the novel synthetases, methods for producing containing the unnatural amino acid phenylselenocysteine and translation systems. The invention further provides methods for producing modified proteins (e.g., lapidated proteins) through targeted modification of the phenylselenocysteine residue in a protein.
FILED Friday, June 08, 2012
APPL NO 13/492240
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/68.100
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US 08394608 Ririe et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Kirk M. Ririe (Salt Lake City, Utah);  Michael R. Newswander (Hyde Park, Utah);  Randy P. Rasmussen (Salt Lake City, Utah);  Mark Aaron Poritz (Salt Lake City, Utah);  Stewart Benjamin Smith (Salt Lake City, Utah);  David E. Jones (Clearfield, Utah);  Gary Clark Kessler (Bountiful, Utah)
ASSIGNEE(S) BioFire Diagnostics, Inc. (Salt Lake City, Utah)
INVENTOR(S) Kirk M. Ririe (Salt Lake City, Utah);  Michael R. Newswander (Hyde Park, Utah);  Randy P. Rasmussen (Salt Lake City, Utah);  Mark Aaron Poritz (Salt Lake City, Utah);  Stewart Benjamin Smith (Salt Lake City, Utah);  David E. Jones (Clearfield, Utah);  Gary Clark Kessler (Bountiful, Utah)
ABSTRACT Devices, containers, and methods are provided for performing biological analysis in a closed environment. Illustrative biological analysis include nucleic acid amplification and detection and immuno-PCR.
FILED Monday, May 08, 2006
APPL NO 11/913120
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/91.200
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US 08394620 Frolov et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Ilya V. Frolov (Galveston, Texas);  Alexandr V. Shustov (Astana, Kazakhstan)
ASSIGNEE(S) The Board of Regents of The University of Texas System (Austin, Texas)
INVENTOR(S) Ilya V. Frolov (Galveston, Texas);  Alexandr V. Shustov (Astana, Kazakhstan)
ABSTRACT The present invention discloses a two-component genome flavivirus and a method for propagating such virus. Since the genetic material of this flavivirus is distributed between two genomes, the flavivirus is deficient in replication, incapable of causing disease but capable of inducing an immune response. Nevertheless, the design of the replication deficient flavivirus discussed herein allows propagation of these flaviviruses at industrial level.
FILED Wednesday, May 07, 2008
APPL NO 12/151491
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/235.100
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US 08394628 Tuschl et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Thomas Tuschl (Goettingen, Germany);  Phillip D. Zamore (Northborough, Massachusetts);  Phillip A. Sharp (Newton, Massachusetts);  David P. Bartel (Brookline, Massachusetts)
ASSIGNEE(S) University of Massachusetts (Boston, Massachusetts);  Whitehead Institute for Biomedical Research (Cambridge, Massachusetts);  Massachusetts Institute of Technology (Cambridge, Massachusetts);  Max-Planck-Gesellschaft zur Förderung der Wissenschaften E.V. (Munich, Germany)
INVENTOR(S) Thomas Tuschl (Goettingen, Germany);  Phillip D. Zamore (Northborough, Massachusetts);  Phillip A. Sharp (Newton, Massachusetts);  David P. Bartel (Brookline, Massachusetts)
ABSTRACT The present invention relates to a Drosophila in vitro system which was used to demonstrate that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore, when these 21-23 nt fragments are purified and added back to Drosophila extracts, they mediate RNA interference in the absence of long dsRNA. Thus, these 21-23 nt fragments are the sequence-specific mediators of RNA degradation. A molecular signal, which may be their specific length, must be present in these 21-23 nt fragments to recruit cellular factors involved in RNAi. This present invention encompasses these 21-23 nt fragments and their use for specifically inactivating gene function. The use of these fragments (or chemically synthesized oligonucleotides of the same or similar nature) enables the targeting of specific mRNAs for degradation in mammalian cells, where the use of long dsRNAs to elicit RNAi is usually not practical, presumably because of the deleterious effects of the interferon response. This specific targeting of a particular gene function is useful in functional genomic and therapeutic applications.
FILED Monday, October 04, 2010
APPL NO 12/897744
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/325
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US 08394641 Winger
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Child Health and Human Development (NICHD)
APPLICANT(S) Theodore Winger (Morrisville, North Carolina)
ASSIGNEE(S) Advanced Liquid Logic Inc. (Research Triangle Park, North Carolina)
INVENTOR(S) Theodore Winger (Morrisville, North Carolina)
ABSTRACT The invention is directed to droplet actuator devices and assay methods. The method may include immobilization of the enzymatic substrate including forming an inclusion complex with the substrate within an aqueous environment in contact with an oil.
FILED Tuesday, November 29, 2011
APPL NO 13/305820
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/86
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US 08394660 Kim et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Human Genome Research Institute (NHGRI)
APPLICANT(S) Samuel Kim (Austin, Texas);  Babak Amirparviz (Seattle, Washington)
ASSIGNEE(S) University of Washington its Center for Commercialization (Seattle, Washington)
INVENTOR(S) Samuel Kim (Austin, Texas);  Babak Amirparviz (Seattle, Washington)
ABSTRACT Devices having features deposited on two sides of a device substrate and methods for making the same. The devices are useful, for example, as the components in a macroelectronic system. In a preferred embodiment, the devices are photosensors having a plurality of electrodes patterned on a first side of the device and an electromagnetic interference filter patterned on a second side of the device. The method facilitates the fabrication of two-sided devices through the use of an immobilizing layer deposited on top of devices patterned on a first side of a device substrate; flipping the device substrate; processing the second side of the device substrate to produce patterned features on the second side of the device substrate; and releasing the devices having patterned elements on two sides of each device.
FILED Friday, November 07, 2008
APPL NO 12/742081
ART UNIT 2829 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/64
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US 08394760 Yang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Lily Yang (Decatur, Georgia);  Shuming Nie (Atlanta, Georgia);  Xiaohu Gao (Shoreline, Washington);  Xiang Hong Peng (Stone Mountain, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Lily Yang (Decatur, Georgia);  Shuming Nie (Atlanta, Georgia);  Xiaohu Gao (Shoreline, Washington);  Xiang Hong Peng (Stone Mountain, Georgia)
ABSTRACT A nanostructure and methods of synthesizing same. In one embodiment, the nanostructure includes a nanospecies, a hydrophobic protection structure including at least one compound selected from a capping ligand, an amphiphilic copolymer, and combinations thereof, wherein the hydrophobic protection structure encapsulates the nanospecies, and at least one histidine-tagged peptide or protein conjugated to the hydrophobic protection structure, wherein the at least one histidine-tagged peptide or protein has at least one binding site.
FILED Tuesday, May 02, 2006
APPL NO 11/919681
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394761 Marchionni et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Mark Marchionni (Arlington, Massachusetts);  Ralph Kelly (Chestnut Hill, Massachusetts);  Beverly Lorell (Needham, Massachusetts);  Douglas B. Sawyer (Brookline, Massachusetts)
ASSIGNEE(S) Beth Israel Deaconess Medical Center (Boston, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Acorda Therapeutics, Inc. (Ardsley, New York)
INVENTOR(S) Mark Marchionni (Arlington, Massachusetts);  Ralph Kelly (Chestnut Hill, Massachusetts);  Beverly Lorell (Needham, Massachusetts);  Douglas B. Sawyer (Brookline, Massachusetts)
ABSTRACT The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.
FILED Wednesday, November 09, 2011
APPL NO 13/292193
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394763 Forte et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Michael Forte (Portland, Oregon);  Dennis Bourdette (Portland, Oregon);  Gail Marracci (Scappoose, Oregon)
ASSIGNEE(S) Oregon Health and Science University (Portland, Oregon);  The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Michael Forte (Portland, Oregon);  Dennis Bourdette (Portland, Oregon);  Gail Marracci (Scappoose, Oregon)
ABSTRACT A method for treating a subject with multiple sclerosis is disclosed herein. In one embodiment, a method is provided for treating a subject with multiple sclerosis that includes administering to the subject a therapeutically effective amount of a cyclosporin compound.
FILED Friday, September 26, 2008
APPL NO 12/679778
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2.900
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394764 Boyd et al.
FUNDED BY
Department of Health and Human Services (HHS)
APPLICANT(S) Michael R. Boyd (Mobile, Alabama);  Toshiyuki Mori (San Francsico, California);  Barry R. O'Keefe (Frederick, Maryland)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia)
INVENTOR(S) Michael R. Boyd (Mobile, Alabama);  Toshiyuki Mori (San Francsico, California);  Barry R. O'Keefe (Frederick, Maryland)
ABSTRACT An isolated and purified nucleic acid molecule that encodes a polypeptide comprising at least eight contiguous amino acids of SEQ ID NO: 3, wherein the at least eight contiguous amino acids have anti-viral activity, as well as an isolated and purified nucleic acid molecule that encodes a polypeptide comprising at least eight contiguous amino acids of SEQ ID NO: 3, wherein the at least eight contiguous amino acids have anti-viral activity, and, when the at least eight contiguous amino acids comprise amino acids 1-121 of SEQ ID NO: 3, the at least eight contiguous amino acids have been rendered glycosylation-resistant, a vector comprising such an isolated and purified nucleic acid molecule, a host cell comprising the nucleic acid molecule, optionally in the form of a vector, a method of producing an anti-viral polypeptide or conjugate thereof, the anti-viral polypeptide itself, a conjugate or fusion protein comprising the anti-viral polypeptide, and compositions comprising an effective amount of the anti-viral polypeptide or conjugate or fusion protein thereof. Further provided are methods of inhibiting prophylactically or therapeutically a viral infection of a host.
FILED Monday, February 07, 2011
APPL NO 13/022289
ART UNIT 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/3.700
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394778 Rao et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Anjana Rao (Cambridge, Massachusetts);  Patrick Hogan (Cambridge, Massachusetts);  Sonia Sharma (Boston, Massachusetts)
ASSIGNEE(S) Immune Disease Institute, Inc. (Boston, Massachusetts)
INVENTOR(S) Anjana Rao (Cambridge, Massachusetts);  Patrick Hogan (Cambridge, Massachusetts);  Sonia Sharma (Boston, Massachusetts)
ABSTRACT Embodiments of the inventions relate to modulating NFAT activity, modulating store-operated Ca2+ entry into a cell and treating and/or preventing hyperactivity or inappropriate immune response by inhibiting the expression or activities of proteins involved in the calcineurin/NFAT axis.
FILED Friday, October 08, 2010
APPL NO 12/901195
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44
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US 08394779 Ingber et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Donald E. Ingber (Boston, Massachusetts);  Charles K. Thodeti (Copley, Ohio)
ASSIGNEE(S) Children's Medical Center Corporation (Boston, Massachusetts)
INVENTOR(S) Donald E. Ingber (Boston, Massachusetts);  Charles K. Thodeti (Copley, Ohio)
ABSTRACT The present invention relates to methods of inhibiting capillary endothelial (CE) cell migration, the formation of CE networks and angiogenesis, and uses thereof for the purpose of treating angiogenesis-related diseases and disorders, particularly when the diseases or disorders are directly related aberrant angiogenesis. Inhibition is achieved by inhibiting TRPV4 activity, such as the levels of TRPV4 expression, calcium influx through TRPV4, and/or the intracellular signaling from TRPV4 via β1 integrin activation.
FILED Thursday, June 04, 2009
APPL NO 12/996069
ART UNIT 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/44.A00
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US 08394788 Verkman et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Alan S. Verkman (San Francisco, California);  Marc Harris Levin (San Francisco, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Alan S. Verkman (San Francisco, California);  Marc Harris Levin (San Francisco, California)
ABSTRACT Provided herein are small molecule compounds that alter the transport activity of solute transporters, particularly urea transporters. The compounds described herein belong to the phenylsulfoxyoxazole, phenylsulfoxyimidazole, phenylsulfoxythiazole class of compounds. The compounds described herein are useful for increasing solute clearance in states of fluid overload and for treating cardiovascular, renal, and metabolic diseases, disorders, and conditions. Methods for identifying and using these agents that inhibit urea transporters are described herein.
FILED Friday, November 16, 2007
APPL NO 12/515000
ART UNIT 1629 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/217.80
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394807 Ghosh
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Arun K. Ghosh (West Lafayette, Indiana)
ASSIGNEE(S) Purdue Research Foundation (West Lafayette, Indiana)
INVENTOR(S) Arun K. Ghosh (West Lafayette, Indiana)
ABSTRACT There is provided a dihydroquinazoline compound of the formula
or a pharmaceutically acceptable salt thereof, wherein the values of the radicals are defined herein, as well as a pharmaceutical composition containing the compound, and a method of using the compound for the treatment of Alzheimer's disease.
FILED Friday, November 20, 2009
APPL NO 13/130508
ART UNIT 1624 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/266.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394811 Samuels et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
APPLICANT(S) Herbert H. Samuels (New Rochelle, New York);  Ruben Abagyan (La Jolla, California);  Matthieu Schapira (Toronto, Canada);  Maxim Totrov (San Diego, California);  Bruce M. Raaka (Rockville, Maryland);  Stephen R. Wilson (Danville, Virginia);  Li Fan (Cambridge, Massachusetts);  Zhiguo Zhou (Winston Salem, North Carolina)
ASSIGNEE(S) Molsoft LLC (La Jolla, California);  New York University School of Medicine (New York, New York)
INVENTOR(S) Herbert H. Samuels (New Rochelle, New York);  Ruben Abagyan (La Jolla, California);  Matthieu Schapira (Toronto, Canada);  Maxim Totrov (San Diego, California);  Bruce M. Raaka (Rockville, Maryland);  Stephen R. Wilson (Danville, Virginia);  Li Fan (Cambridge, Massachusetts);  Zhiguo Zhou (Winston Salem, North Carolina)
ABSTRACT A method of identification of compounds that modulate thyroid hormone activity, and the use of such compounds and compositions thereof for such purposes are disclosed. The compounds may be selected from the group consisting of:
The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of conditions that are causally related to aberrant thyroid hormone activity, such as hyperthyroidism and thyrotoxicosis.
FILED Friday, April 18, 2008
APPL NO 12/450922
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/278
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US 08394818 Gray et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Nathanael Gray (Boston, Massachusetts);  Jae Won Chang (Boston, Massachusetts);  Jianming Zhang (Cambridge, Massachusetts);  Carson C. Thoreen (Jamaica Plain, Massachusetts);  Seong Woo Anthony Kang (Cambridge, Massachusetts);  David M. Sabatini (Cambridge, Massachusetts);  Qingsong Liu (Jamaica Plain, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts);  Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S) Nathanael Gray (Boston, Massachusetts);  Jae Won Chang (Boston, Massachusetts);  Jianming Zhang (Cambridge, Massachusetts);  Carson C. Thoreen (Jamaica Plain, Massachusetts);  Seong Woo Anthony Kang (Cambridge, Massachusetts);  David M. Sabatini (Cambridge, Massachusetts);  Qingsong Liu (Jamaica Plain, Massachusetts)
ABSTRACT The present invention relates to small molecule modulators of mTORC1 and mTORC2, syntheses thereof, and intermediates thereto. Such small molecule modulators are useful in the treatment of proliferative diseases (e.g., benign neoplasms, cancers, inflammatory diseases, autoimmune diseases, diabetic retinopathy) and metabolic diseases. Novel small molecules are provided that inhibit one or more of mTORC1, mTORC2, and PI3K-related proteins. Novel methods of providing soluble mTORC1 and mTORC2 complexes are discussed, as well as methods of using the soluble complexes in a high-throughput manner to screen for inhibitory compounds.
FILED Friday, October 16, 2009
APPL NO 13/124159
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/292
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US 08394839 Timmins et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) Graham Timmins (Albuquerque, New Mexico);  Vojo P Deretic (Placitas, New Mexico)
ASSIGNEE(S) STC.UNM (Albuquerque, New Mexico);  The John Hopkins University (Baltimore, Maryland)
INVENTOR(S) Graham Timmins (Albuquerque, New Mexico);  Vojo P Deretic (Placitas, New Mexico)
ABSTRACT The present invention relates to the use of isotopically labeled derivatives of isoniazid, ethionamide and related compounds as effective therapy for the treatment of mycobacterial diseases, including Mycobacterium tuberculosis.
FILED Wednesday, August 20, 2008
APPL NO 12/674188
ART UNIT 1622 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/354
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US 08394924 Wittrup et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Allergy and Infectious Diseases (NIAID)
APPLICANT(S) K. Dane Wittrup (Chestnut Hill, Massachusetts);  Shanshan Wu Howland (Singapore, Singapore)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) K. Dane Wittrup (Chestnut Hill, Massachusetts);  Shanshan Wu Howland (Singapore, Singapore)
ABSTRACT The present invention features engineered proteins that include a first polypeptide that specifically binds a first target (e.g., a cellular target, such as a cell-surface antigen) and a second polypeptide that selectively binds an activating FcR.
FILED Friday, October 23, 2009
APPL NO 12/605273
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/350
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394929 Strittmatter
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Stephen M. Strittmatter (Guilford, Connecticut)
ASSIGNEE(S) Yale University (New Haven, Connecticut)
INVENTOR(S) Stephen M. Strittmatter (Guilford, Connecticut)
ABSTRACT Disclosed are NgR proteins and biologically active Nogo (ligand) protein fragments. Also disclosed are compositions and methods for modulating the expression or activity of the Nogo and NgR protein. Also disclosed are peptides which block Nogo-mediated inhibition of axonal extension. The compositions and methods of the invention are useful in the treatment of cranial or cerebral trauma, spinal cord injury, stroke or a demyelinating disease.
FILED Tuesday, January 26, 2010
APPL NO 12/693940
ART UNIT 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
530/387.900
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394945 Sampath et al.
FUNDED BY
Department of Health and Human Services (HHS)
Centers for Disease Control and Prevention (CDC)
APPLICANT(S) Rangarajan Sampath (San Diego, California);  Thomas A. Hall (Oceanside, California);  David J. Ecker (Encinitas, California);  Lawrence Blyn (Mission Viejo, California)
ASSIGNEE(S) Ibis Biosciences, Inc. (Carlsbad, California)
INVENTOR(S) Rangarajan Sampath (San Diego, California);  Thomas A. Hall (Oceanside, California);  David J. Ecker (Encinitas, California);  Lawrence Blyn (Mission Viejo, California)
ABSTRACT The present invention provides compositions, kits and methods for rapid identification and quantification of bacteria by molecular mass and base composition analysis.
FILED Wednesday, March 07, 2007
APPL NO 11/683286
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Organic compounds
536/24.330
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394950 Furneaux et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Richard Hubert Furneaux (Wellington, New Zealand);  Peter Charles Tyler (Wellington, New Zealand);  Gary Brian Evans (Lower Hutt, New Zealand);  Vern L. Schramm (New Rochelle, New York);  Kami Kim (New York, New York);  Richard Fröhlich (Wellington, New Zealand)
ASSIGNEE(S) Industrial Research Limited (Lower Hutt, New Zealand);  Albert Einstein College of Medicine of Yeshiva University (Bronx, New York)
INVENTOR(S) Richard Hubert Furneaux (Wellington, New Zealand);  Peter Charles Tyler (Wellington, New Zealand);  Gary Brian Evans (Lower Hutt, New Zealand);  Vern L. Schramm (New Rochelle, New York);  Kami Kim (New York, New York);  Richard Fröhlich (Wellington, New Zealand)
ABSTRACT This invention relates to compounds that are analogues of coformycin, pharmaceutical compositions containing the compounds, and methods of using the compounds for treating protozoan parasite infections, especially malaria.
FILED Thursday, February 22, 2007
APPL NO 12/223746
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Organic compounds
536/27.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394957 Joshi et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Harish C. Joshi (Decatur, Georgia);  Ritu Aneja (Lilburn, Georgia);  Surya N. Vangapandu (Alpharetta, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Harish C. Joshi (Decatur, Georgia);  Ritu Aneja (Lilburn, Georgia);  Surya N. Vangapandu (Alpharetta, Georgia)
ABSTRACT 9-aminonoscapine, prodrugs thereof, and pharmaceutically acceptable salts thereof, are disclosed. Pharmaceutical compositions including 9-aminonoscapine, and methods of preparation and use thereof are disclosed. 9-aminonoscapine is a noscapine analog that can be used to treat and/or prevent a wide variety of cancers, including drug resistant cancers, by binding tubulin and inducing apoptosis selectively in tumor cells (ovarian and T-cell lymphoma) resistant to paclitaxel, vinblastine and teniposide. 9-aminonoscapine can perturb the progression of cell cycle by mitotic arrest, followed by apoptotic cell death associated with increased caspase-3 activation and appearance of TUNEL-positive cells. Thus, 9-aminonoscapine is a novel therapeutic agents for a variety of cancers, including ovarian and T-cell lymphoma cancers, even those that have become drug-resistant to currently available chemotherapeutic drugs.
FILED Friday, September 04, 2009
APPL NO 13/062481
ART UNIT 1625 — Organic Chemistry
CURRENT CPC
Organic compounds
546/90
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US 08396267 Lake et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
APPLICANT(S) David S. Lake (Rochester, Minnesota);  Armando Manduca (Rochester, Minnesota);  Jeffrey S. McAllister (St. Paul, Minnesota);  Timothy J. Mullins (Blaine, Minnesota);  Nelson Ramirez (Rochester, Minnesota)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) David S. Lake (Rochester, Minnesota);  Armando Manduca (Rochester, Minnesota);  Jeffrey S. McAllister (St. Paul, Minnesota);  Timothy J. Mullins (Blaine, Minnesota);  Nelson Ramirez (Rochester, Minnesota)
ABSTRACT Systems, methods and articles of manufacture are disclosed for compensating for motion of a subject during an MRI scan of the subject. k-space data may be received from the MRI scan of the subject. A first graphical image may be generated from a first set of data elements from the k-space data. Similarly, a second graphical image may be generated from a second set of data elements from the k-space data. An offset in pixels may be determined by which to translate the second graphical image from the first graphical image to compensate for the motion. The k-space data may be modified at a sub-pixel offset relative to the determined offset. A motion-compensated graphical image of the subject may be generated from the modified k-space data. Doing so reduces the search space evaluated to sharpen images generated from the k-space data.
FILED Wednesday, November 04, 2009
APPL NO 12/612105
ART UNIT 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/128
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US 08396270 Keall et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Paul J. Keall (Greenwich, Australia);  Per Rugaard Poulsen (Aabyhoej, Denmark);  Byungchul Cho (Anyang, South Korea)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Paul J. Keall (Greenwich, Australia);  Per Rugaard Poulsen (Aabyhoej, Denmark);  Byungchul Cho (Anyang, South Korea)
ABSTRACT A method of estimating target motion for image guided radiotherapy (IGRT) systems is provided. The method includes acquiring by a kV imaging system sequential images of a target motion, computing by the kV imaging system from the sequential images an image-based estimation of the target motion expressed in a patient coordinate system, transforming by the kV imaging system the image-based estimation in the patient coordinate system to an estimate in a projection coordinate system, reformulating by the kV imaging system the projection coordinate system in a converging iterative form to force a convergence of the projection coordinate system to output a resolved estimation of the target motion, and displaying by the kV imaging system the resolved estimation of the target motion.
FILED Wednesday, February 16, 2011
APPL NO 12/932060
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/128
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US 08396526 Benni
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Paul Benni (Guilford, Connecticut)
ASSIGNEE(S) CAS Medical Systems, Inc. (Branford, Connecticut)
INVENTOR(S) Paul Benni (Guilford, Connecticut)
ABSTRACT According to the present invention, a method and apparatus for non-invasively determining the blood oxygen saturation level within a subject's tissue is provided. The method comprises the steps of: 1) providing a near infrared spectrophotometric sensor operable to transmit light along a plurality of wavelengths into the subject's tissue; 2) sensing the light transmitted into the subject's tissue using the sensor, and producing signal data representative of the light sensed from the subject's tissue; 3) processing the signal data to account for physical characteristics of the subject; and 4) determining the blood oxygen saturation level within the subject's tissue using a difference in attenuation between the wavelengths. The apparatus includes a sensor having a light source and at least one light detector, which sensor is operably connected to a processor. The sensor is operable to transmit light along a plurality of wavelengths into the subject's tissue, and produce signal data representative of the light sensed from the subject's tissue. The algorithm is operable to process the signal data to account for the physical characteristics of the subject being sensed.
FILED Wednesday, May 10, 2006
APPL NO 11/914074
ART UNIT 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
6/323
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US 08396535 Wang et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Wei-Chih Wang (Sammamish, Washington);  Eric Seibel (Seattle, Washington);  Per Reinhall (Seattle, Washington);  Mark Fauver (Seattle, Washington);  Chris Brown (Seattle, Washington)
ASSIGNEE(S) University of Washington (Seattle, Washington)
INVENTOR(S) Wei-Chih Wang (Sammamish, Washington);  Eric Seibel (Seattle, Washington);  Per Reinhall (Seattle, Washington);  Mark Fauver (Seattle, Washington);  Chris Brown (Seattle, Washington)
ABSTRACT An apparatus and method for providing image acquisition and/or image display in a limited region of interest (ROI). The apparatus comprises a micro-electro-mechanical system (MEMS), preferably integrating a light source, a cantilever, a lens, an actuator, a light detector, and a position sensor. The light source provides light for illuminating the ROI, displaying an image, providing a therapy, and/or performing other functions. The cantilever comprises a resin waveguide with a fixed end attached to a substrate that supports many or all other components. A free end of the cantilever is released from the substrate during fabrication and includes the lens. The actuator scans the free end in orthogonal directions to illuminate the ROI or display an image. The position sensors detect the position of the free end for control. The light detector receives light backscattered from the ROI separate from, or at the fixed end of the cantilever.
FILED Friday, May 01, 2009
APPL NO 12/434129
ART UNIT 3737 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting
CURRENT CPC
Surgery
6/476
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US 08396542 Johnson et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Heart, Lung, and Blood Institute (NHLBI)
APPLICANT(S) Steven R. Johnson (Fair Haven, New Jersey);  Bruce Hopenfeld (Salt Lake City, Utah)
ASSIGNEE(S) Angel Medical Systems, Inc. (Fair Haven, New Jersey)
INVENTOR(S) Steven R. Johnson (Fair Haven, New Jersey);  Bruce Hopenfeld (Salt Lake City, Utah)
ABSTRACT A heart monitor is disclosed. The monitor computes ST segment deviations and stores the results in heart rate based histograms. Periodically, the monitor analyzes the histogram data to determine a median value of ST deviation. Subsequently, beats are excluded from the computation of the time series if their ST deviations both varies too far from the long term median value and varies too far from the then current time series value.
FILED Thursday, October 28, 2010
APPL NO 12/914548
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery
6/515
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US 08396545 Berridge et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute on Drug Abuse (NIDA)
National Institute of Mental Health (NIMH)
APPLICANT(S) Craig W. Berridge (Madison, Wisconsin);  David M. Devilbiss (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) Craig W. Berridge (Madison, Wisconsin);  David M. Devilbiss (Madison, Wisconsin)
ABSTRACT Methods, apparatuses, and systems for analysis of electromagnetic activity of prefrontal cortex neurons in subjects are provided. The methods, apparatuses, and systems of the present invention can be used as a means to screen for cognitive modulators. They can be used to predict the effects of compounds such as psychostimulants and other drugs on prefrontal cortex-dependent cognition.
FILED Tuesday, February 24, 2009
APPL NO 12/391406
ART UNIT 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Surgery
6/544
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US 08396558 Keller et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Neurological Disorders and Stroke (NINDS)
APPLICANT(S) Asaf Keller (Baltimore, Maryland);  Radi Masri (Ellicott City, Maryland);  Raimi Quiton (Baltimore, Maryland)
ASSIGNEE(S) University of Maryland, Baltimore (Baltimore, Maryland)
INVENTOR(S) Asaf Keller (Baltimore, Maryland);  Radi Masri (Ellicott City, Maryland);  Raimi Quiton (Baltimore, Maryland)
ABSTRACT Central pain syndrome (CPS) is a debilitating condition that affects a large number of patients with a primary lesion or dysfunction in the central nervous system. Despite its discovery over a century ago, the pathophysiology underlying the development and maintenance of CPS is poorly understood. The present invention is drawn to novel methods of treating CPS. In certain aspects, the invention is drawn to the novel discovery of the role of the zona incerta (ZI) in CPS and methods of exploiting this novel discovery for the treatment of CPS.
FILED Thursday, February 04, 2010
APPL NO 12/699918
ART UNIT 3766 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/46
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US 08396561 Pezaris et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) John S. Pezaris (Cambridge, Massachusetts);  R. Clay Reid (Cambridge, Massachusetts);  Emad N. Eskandar (Nahant, Massachusetts)
ASSIGNEE(S) The General Hospital Corporation (Boston, Massachusetts);  President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) John S. Pezaris (Cambridge, Massachusetts);  R. Clay Reid (Cambridge, Massachusetts);  Emad N. Eskandar (Nahant, Massachusetts)
ABSTRACT A visual prosthesis and methods of allowing a subject to view visual information from an artificial source are provided. The visual prosthesis has one or more electrodes operative to deliver electrical signals to a lateral geniculate nucleus of a mammal, a power supply operative to provide power to the electrodes, a visual information translator operatively connected to the electrode array, and a visual sensor operatively connected to the visual information translator. The visual prosthesis is operative to translate visual information into an electrical signal and transmit the electrical signal to electrodes to stimulate brain activity to recognize visual information.
FILED Thursday, December 20, 2007
APPL NO 12/520741
ART UNIT 3762 — Refrigeration, Vaporization, Ventilation, and Combustion
CURRENT CPC
Surgery: Light, thermal, and electrical application
67/54
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Department of Defense (DOD) 

US 08393049 Vogel
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Hans E. Vogel (Palmer, Alaska)
ASSIGNEE(S) Triverus, LLC (Palmer, Alaska)
INVENTOR(S) Hans E. Vogel (Palmer, Alaska)
ABSTRACT A method and apparatus for cleaning large surface areas. The method and vehicle clean large surface areas such as streets, runways, aircraft carrier decks, and the like, wherein a substantial portion of the soiled water is recaptured, processed, and reused.
FILED Thursday, May 06, 2010
APPL NO 12/775279
ART UNIT 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Brushing, scrubbing, and general cleaning
015/320
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US 08393062 Alexander
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Naval Air Systems Command (NAVAIR)
APPLICANT(S) Phillip Alexander (Colchester, Connecticut)
ASSIGNEE(S) United Technologies Corp. (Hartford, Connecticut)
INVENTOR(S) Phillip Alexander (Colchester, Connecticut)
ABSTRACT Systems and methods for positioning fairing sheaths are provided. In this regard, a representative method includes using vacuum pressure to assist in moving opposing portions of a fairing sheath away from each other.
FILED Monday, March 31, 2008
APPL NO 12/059235
ART UNIT 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units
CURRENT CPC
Metal working
029/21
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US 08393198 Martin et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
APPLICANT(S) Tyler P. Martin (Bangor, Maine);  Luke Doucette (Hampden, Maine);  Dean J. Smith (Dover-Foxcroft, Maine);  Thomas P. Schwarz (Orono, Maine)
ASSIGNEE(S) OronoSpectral Solutions, Inc. (Bangor, Maine)
INVENTOR(S) Tyler P. Martin (Bangor, Maine);  Luke Doucette (Hampden, Maine);  Dean J. Smith (Dover-Foxcroft, Maine);  Thomas P. Schwarz (Orono, Maine)
ABSTRACT An apparatus and method to determine analytes in a fluid. One aspect of the present invention is for the determination of the oil content of water using UV, near-IR, IR or Raman spectroscopy or radiometry. In certain embodiments, a solid membrane material absorbs analytes from fluid brought into contact with it. The membrane is subsequently placed in a FTIR spectrometer, which spectrometer is enabled to determine the concentration of analytes in fluid by calibration. Certain embodiments can determine the type of hydrocarbon present, and thus can differentiate Total Petroleum Hydrocarbons (TPH) from Total Oil and Grease (TOG), without any separate sample preparation.
FILED Wednesday, November 26, 2008
APPL NO 12/324688
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/61.410
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08393368 Bichsel
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Steve L. Bichsel (Arlington, Texas)
ASSIGNEE(S) Lockheed Martin Corporation (Bethesda, Maryland)
INVENTOR(S) Steve L. Bichsel (Arlington, Texas)
ABSTRACT A method of manufacturing a composite structure by compacting layers of laminate material within a mold and then curing the layers of laminate material within the mold.
FILED Monday, June 01, 2009
APPL NO 12/475923
ART UNIT 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Adhesive bonding and miscellaneous chemical manufacture
156/358
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US 08393581 Keller et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Department of the Navy (DON)
Office of Naval Research (ONR)
APPLICANT(S) Philip N. Keller (Longmont, Colorado);  Robert Taylor (Superior, Colorado);  Doug Richardson (Westminster, Colorado);  Adam G. Gray (Broomfield, Colorado)
ASSIGNEE(S) Composite Technology Development, Inc. (Lafayette, Colorado)
INVENTOR(S) Philip N. Keller (Longmont, Colorado);  Robert Taylor (Superior, Colorado);  Doug Richardson (Westminster, Colorado);  Adam G. Gray (Broomfield, Colorado)
ABSTRACT Structures and methods are disclosed regarding deployable structures with expandable longerons adjustably coupled with supporting structures such that an angle between the supporting structures can be adjusted. Such structures can include and/or be used for solar arrays, bridges, support structures, and more. These structures can be easily transported to a new location and deployed from the stowed configuration into a larger functional structure. In some embodiments these structures can use one or more longerons that can have two resting states: deployed and rolled.
FILED Tuesday, November 22, 2011
APPL NO 13/302631
ART UNIT 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review
CURRENT CPC
Aeronautics and astronautics
244/172.200
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08393857 Copeland et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
APPLICANT(S) Andy Copeland (Greenwood, Indiana);  Linnea Ohlsson (Indianapolis, Indiana);  Ted Freeman (Avon, Indiana)
ASSIGNEE(S) Rolls-Royce Corporation (Indianapolis, Indiana)
INVENTOR(S) Andy Copeland (Greenwood, Indiana);  Linnea Ohlsson (Indianapolis, Indiana);  Ted Freeman (Avon, Indiana)
ABSTRACT A variable vane actuation system is disclosed herein. The variable vane actuation system includes a first vane having a first vane axis. The variable vane actuation system also includes an actuator operably engaged with the first vane to selectively pivot the first vane about the first vane axis. The variable vane actuation system also includes a ring member operably connected with the first vane. The ring member is disposed for pivoting movement about a centerline axis transverse to the first vane axis. The variable vane actuation system also includes a second vane having a second vane axis spaced from the first vane axis about the centerline axis. The second vane is operably connected with the ring member. Forces moving the second vane are generated by the actuator and transmitted first through the first vane and then through the ring member before being applied to the second vane.
FILED Friday, October 09, 2009
APPL NO 12/576810
ART UNIT 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/160
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US 08393858 Smoke et al.
FUNDED BY
Department of Defense (DOD)
APPLICANT(S) Jason Smoke (Phoenix, Arizona);  Michael Kahrs (Phoenix, Arizona)
ASSIGNEE(S) Honeywell International Inc. (Morristown, New Jersey)
INVENTOR(S) Jason Smoke (Phoenix, Arizona);  Michael Kahrs (Phoenix, Arizona)
ABSTRACT A coupling assembly for a turbine shroud is provided. The coupling assembly comprises a rotatable positioning block having a first surface, and a biasing spring having a second surface, the second surface generally facing the first surface, and the biasing spring adapted to exert a force toward the positioning block when compressed.
FILED Friday, March 13, 2009
APPL NO 12/403765
ART UNIT 2895 — Semiconductors/Memory
CURRENT CPC
Rotary kinetic fluid motors or pumps
415/173.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394249 Pollack et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Michael G. Pollack (Durham, North Carolina);  Vamsee K. Pamula (Durham, North Carolina);  Richard B. Fair (Durham, North Carolina)
ASSIGNEE(S) Duke University (Durham, North Carolina)
INVENTOR(S) Michael G. Pollack (Durham, North Carolina);  Vamsee K. Pamula (Durham, North Carolina);  Richard B. Fair (Durham, North Carolina)
ABSTRACT Methods are provided for manipulating droplets. The methods include providing the droplet on a surface comprising an array of electrodes and a substantially co-planer array of reference elements, wherein the droplet is disposed on a first one of the electrodes, and the droplet at least partially overlaps a second one of the electrodes and an intervening one of the reference elements disposed between the first and second electrodes. The methods further include activating the first and second electrodes to spread at least a portion of the droplet across the second electrode and deactivating the first electrode to move the droplet from the first electrode to the second electrode.
FILED Tuesday, June 30, 2009
APPL NO 12/494927
ART UNIT 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry: Electrical and wave energy
24/450
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US 08394330 Lewis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
APPLICANT(S) Nathan S. Lewis (La Canada, California);  Carol Lewis (La Canada, California);  Robert Grubbs (South Pasadena, California);  Gregory Allen Sotzing (Willington, Connecticut)
ASSIGNEE(S) The California Institute of Technology (Pasadena, California)
INVENTOR(S) Nathan S. Lewis (La Canada, California);  Carol Lewis (La Canada, California);  Robert Grubbs (South Pasadena, California);  Gregory Allen Sotzing (Willington, Connecticut)
ABSTRACT The present invention provides a class of sensors prepared from regions of conducting organic materials and conducting materials that show an increase sensitivity detection limit for amines. The present class of sensors have applications in the detection of spoiled food products and in testing for diseases, such as cholera and lung cancer, which have amines as biomarkers.
FILED Friday, October 01, 1999
APPL NO 09/409644
ART UNIT 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
422/98
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US 08394590 Kwong et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
APPLICANT(S) Gabriel A. Kwong (Alhambra, California);  Caius G. Radu (Los Angeles, California);  Owen Witte (Sherman Oaks, California);  James R. Heath (South Pasadena, California);  Antoni Ribas (Los Angeles, California)
ASSIGNEE(S) California Institute of Technology (Pasadena, California);  University of California (Oakland, California)
INVENTOR(S) Gabriel A. Kwong (Alhambra, California);  Caius G. Radu (Los Angeles, California);  Owen Witte (Sherman Oaks, California);  James R. Heath (South Pasadena, California);  Antoni Ribas (Los Angeles, California)
ABSTRACT Polynucleotide-encoded capture agents for target detection and in particular modular polynucleotide-capture agents comprising a target binding component, a scaffold component and an encoding component formed by standardized molecular units that can be coupled and decoupled in a controlled fashion, and related compositions methods and systems.
FILED Friday, October 08, 2010
APPL NO 12/901151
ART UNIT 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/6.120
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394632 Noll et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Lee Noll (Whitmore Lake, Michigan);  Brian Hampson (Canton, Michigan);  Kristin Goltry (Milan, Michigan);  Samantha Snabes (Houston, Texas)
ASSIGNEE(S) Aastrom Biosciences, Inc. (Ann Arbor, Michigan)
INVENTOR(S) Lee Noll (Whitmore Lake, Michigan);  Brian Hampson (Canton, Michigan);  Kristin Goltry (Milan, Michigan);  Samantha Snabes (Houston, Texas)
ABSTRACT The present invention relates to methods of generating an ex vivo tissue-like system in a bioreactor system capable of supporting continuous production of, and output of cells and tissues and an ex vivo tissue system made therefrom.
FILED Tuesday, November 10, 2009
APPL NO 12/615446
ART UNIT 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/401
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US 08394640 Golovchenko et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S) Jene A. Golovchenko (Lexington, Massachusetts);  Jiali Li (Fayetteville, Arkansas);  Derek Stein (Delft, Netherlands);  Marc H. Gershow (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jene A. Golovchenko (Lexington, Massachusetts);  Jiali Li (Fayetteville, Arkansas);  Derek Stein (Delft, Netherlands);  Marc H. Gershow (Cambridge, Massachusetts)
ABSTRACT The invention features methods for evaluating the conformation of a polymer, for example, for determining the conformational distribution of a plurality of polymers and to detect binding or denaturation events. The methods employ a nanopore which the polymer, e.g., a nucleic acid, traverses. As the polymer traverses the nanopore, measurements of transport properties of the nanopore yield data on the conformation of the polymer.
FILED Monday, December 06, 2010
APPL NO 12/961021
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/86
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394645 Beebe et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) David J. Beebe (Monona, Wisconsin);  Ivar Meyvantsson (Madison, Wisconsin)
ASSIGNEE(S) Wisconsin Alumni Research Foundation (Madison, Wisconsin)
INVENTOR(S) David J. Beebe (Monona, Wisconsin);  Ivar Meyvantsson (Madison, Wisconsin)
ABSTRACT A device and method is provided for performing a high throughput assay. The device includes a plate structure having a plate and a plurality of microfluidic structures positioned thereon. Each microfluidic structure defines a channel having an input and an output. At least one of the input and the output of the channel of each of the plurality of mircofluidic structures includes a first plurality of ports. In operation, the channels are filled with fluid and pressure gradients are generated between the fluids at the inputs and the fluids at the outputs of the channels. As a result, fluid flows through the channels toward the outputs.
FILED Thursday, March 01, 2012
APPL NO 13/409626
ART UNIT 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/180
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US 08394651 Efros et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Alexander L. Efros (Annandale, Virginia);  George E. Cragg (Washington, District of Columbia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Alexander L. Efros (Annandale, Virginia);  George E. Cragg (Washington, District of Columbia)
ABSTRACT The present invention is generally directed to a method of suppressing the Auger rate in confined structures, comprising replacing an abrupt confinement potential with either a smooth confinement potential or a confinement potential of a certain size found by increasing the confinement potential width until the Auger recombination rate undergoes strong oscillations and establishes a periodic minima. In addition, the present invention provides for the design of structures with high quantum efficiency.
FILED Tuesday, December 22, 2009
APPL NO 12/644011
ART UNIT 2896 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Semiconductor device manufacturing: Process
438/20
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US 08394664 Nicholas et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) Nolan Walker Nicholas (Houston, Texas);  W. Carter Kittrell (Houston, Texas);  Myung Jong Kim (Houston, Texas);  Howard K. Schmidt (Cypress, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Nolan Walker Nicholas (Houston, Texas);  W. Carter Kittrell (Houston, Texas);  Myung Jong Kim (Houston, Texas);  Howard K. Schmidt (Cypress, Texas)
ABSTRACT A method for forming nanotube electrical devices, arrays of nanotube electrical devices, and device structures and arrays of device structures formed by the methods. Various methods of the present invention allow creation of semiconducting and/or conducting devices from readily grown SWNT carpets rather than requiring the preparation of a patterned growth channel and takes advantage of the self-controlling nature of these carpet heights to ensure a known and controlled channel length for reliable electronic properties as compared to the prior methods.
FILED Friday, February 02, 2007
APPL NO 11/910522
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/99
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US 08394706 Nuzzo et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Energy (DOE)
Office of Science (DOE-SC)
Materials Sciences and Engineering Division (MSE)
APPLICANT(S) Ralph G. Nuzzo (Champaign, Illinois);  John A. Rogers (Champaign, Illinois);  Etienne Menard (Durham, North Carolina);  Keon Jae Lee (Tokyo, Japan);  Dahl-Young Khang (Urbana, Illinois);  Yugang Sun (Westmont, Illinois);  Matthew Meitl (Raleigh, North Carolina);  Zhengtao Zhu (Rapid City, South Dakota);  Heung Cho Ko (Urbana, Illinois);  Shawn Mack (Goleta, California)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Ralph G. Nuzzo (Champaign, Illinois);  John A. Rogers (Champaign, Illinois);  Etienne Menard (Durham, North Carolina);  Keon Jae Lee (Tokyo, Japan);  Dahl-Young Khang (Urbana, Illinois);  Yugang Sun (Westmont, Illinois);  Matthew Meitl (Raleigh, North Carolina);  Zhengtao Zhu (Rapid City, South Dakota);  Heung Cho Ko (Urbana, Illinois);  Shawn Mack (Goleta, California)
ABSTRACT The present invention provides a high yield pathway for the fabrication, transfer and assembly of high quality printable semiconductor elements having selected physical dimensions, shapes, compositions and spatial orientations. The compositions and methods of the present invention provide high precision registered transfer and integration of arrays of microsized and/or nanosized semiconductor structures onto substrates, including large area substrates and/or flexible substrates. In addition, the present invention provides methods of making printable semiconductor elements from low cost bulk materials, such as bulk silicon wafers, and smart-materials processing strategies that enable a versatile and commercially attractive printing-based fabrication platform for making a broad range of functional semiconductor devices.
FILED Tuesday, October 11, 2011
APPL NO 13/270954
ART UNIT 2823 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/458
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US 08394760 Yang et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Lily Yang (Decatur, Georgia);  Shuming Nie (Atlanta, Georgia);  Xiaohu Gao (Shoreline, Washington);  Xiang Hong Peng (Stone Mountain, Georgia)
ASSIGNEE(S) Emory University (Atlanta, Georgia)
INVENTOR(S) Lily Yang (Decatur, Georgia);  Shuming Nie (Atlanta, Georgia);  Xiaohu Gao (Shoreline, Washington);  Xiang Hong Peng (Stone Mountain, Georgia)
ABSTRACT A nanostructure and methods of synthesizing same. In one embodiment, the nanostructure includes a nanospecies, a hydrophobic protection structure including at least one compound selected from a capping ligand, an amphiphilic copolymer, and combinations thereof, wherein the hydrophobic protection structure encapsulates the nanospecies, and at least one histidine-tagged peptide or protein conjugated to the hydrophobic protection structure, wherein the at least one histidine-tagged peptide or protein has at least one binding site.
FILED Tuesday, May 02, 2006
APPL NO 11/919681
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
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US 08394762 Wynne et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) James H Wynne (Alexandria, Virginia);  Preston A Fulmer (Richmond, Virginia)
ASSIGNEE(S) The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) James H Wynne (Alexandria, Virginia);  Preston A Fulmer (Richmond, Virginia)
ABSTRACT Disclosed herein is a composition having: a polymeric material and an antimicrobial peptide derived from Chrysophrys major. Also disclosed herein is a method of: combining the polymeric material and antimicrobial peptide to form a coating material, and applying the coating material to a surface.
FILED Friday, April 29, 2011
APPL NO 13/097175
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2.400
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US 08394818 Gray et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Cancer Institute (NCI)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Nathanael Gray (Boston, Massachusetts);  Jae Won Chang (Boston, Massachusetts);  Jianming Zhang (Cambridge, Massachusetts);  Carson C. Thoreen (Jamaica Plain, Massachusetts);  Seong Woo Anthony Kang (Cambridge, Massachusetts);  David M. Sabatini (Cambridge, Massachusetts);  Qingsong Liu (Jamaica Plain, Massachusetts)
ASSIGNEE(S) Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts);  Whitehead Institute for Biomedical Research (Cambridge, Massachusetts)
INVENTOR(S) Nathanael Gray (Boston, Massachusetts);  Jae Won Chang (Boston, Massachusetts);  Jianming Zhang (Cambridge, Massachusetts);  Carson C. Thoreen (Jamaica Plain, Massachusetts);  Seong Woo Anthony Kang (Cambridge, Massachusetts);  David M. Sabatini (Cambridge, Massachusetts);  Qingsong Liu (Jamaica Plain, Massachusetts)
ABSTRACT The present invention relates to small molecule modulators of mTORC1 and mTORC2, syntheses thereof, and intermediates thereto. Such small molecule modulators are useful in the treatment of proliferative diseases (e.g., benign neoplasms, cancers, inflammatory diseases, autoimmune diseases, diabetic retinopathy) and metabolic diseases. Novel small molecules are provided that inhibit one or more of mTORC1, mTORC2, and PI3K-related proteins. Novel methods of providing soluble mTORC1 and mTORC2 complexes are discussed, as well as methods of using the soluble complexes in a high-throughput manner to screen for inhibitory compounds.
FILED Friday, October 16, 2009
APPL NO 13/124159
ART UNIT 1626 — Organic Chemistry
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/292
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US 08394889 Bulluck et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) John W. Bulluck (Spicewood, Texas);  Brad A. Rix (Spicewood, Texas)
ASSIGNEE(S) Texas Research International Inc. (Austin, Texas)
INVENTOR(S) John W. Bulluck (Spicewood, Texas);  Brad A. Rix (Spicewood, Texas)
ABSTRACT A composition and process for manufacturing a camouflaged aircraft component. The process includes providing an aircraft component; applying an uncured coating onto the aircraft component wherein the uncured coating comprises polysilazane resin, at least one pigment, at least one matting agent, and at least one diluent; allowing the diluent to evaporate; curing the coating to provided a cured coating that comprises cured polysilazane, at least one pigment, and at least one matting agent.
FILED Tuesday, March 22, 2011
APPL NO 13/065449
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
524/588
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US 08394917 Amb et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
APPLICANT(S) Chad Martin Amb (Gainesville, Florida);  Pierre Marc Beaujuge (Berkeley, California);  John R. Reynolds (Gainesville, Florida)
ASSIGNEE(S) University of Florida Research Foundation, Inc. (Gainesville, Florida)
INVENTOR(S) Chad Martin Amb (Gainesville, Florida);  Pierre Marc Beaujuge (Berkeley, California);  John R. Reynolds (Gainesville, Florida)
ABSTRACT Embodiments of the invention are directed to alternating donor-acceptor (DA) polymers that are soluble and display a blue or green neutral state that oxidizes to a transmissive state for use as an electrochromic polymer. The D units have 3,4-dioxythiophene, 3,6-dialkoxythieno[3,2-b]thiophene or 3,5-dialkoxy-dithieno[3,2-b:2′,3′-d]thiophene groups. Embodiments of the invention are directed to a method for preparation of the alternating DA polymeric sequences of the DA polymers by a cross-condensation of a nucleophilic acceptor monomer and an electrophilic donor monomer.
FILED Friday, July 02, 2010
APPL NO 12/829903
ART UNIT 1766 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
528/377
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US 08394953 Kassis
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Amin I. Kassis (Chestnut Hill, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Amin I. Kassis (Chestnut Hill, Massachusetts)
ABSTRACT The invention provides methods and compositions, e.g., for tumor imaging and therapy.
FILED Monday, June 01, 2009
APPL NO 12/476102
ART UNIT 1627 — Organic Chemistry
CURRENT CPC
Organic compounds
544/283
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US 08395007 Wright et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Michael E. Wright (Ridgecrest, California);  Benjamin G. Harvey (Ridgecrest, California);  Roxanne L. Quintana (Ridgecrest, California)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael E. Wright (Ridgecrest, California);  Benjamin G. Harvey (Ridgecrest, California);  Roxanne L. Quintana (Ridgecrest, California)
ABSTRACT A renewable biofuel based on a highly efficient batch catalysis methodology for conversion of 1-butene to a new class of potential jet fuel blends. By tuning the catalyst and then using the dimer produced, the carbon use is about 95% or greater.
FILED Wednesday, July 29, 2009
APPL NO 12/511796
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry of hydrocarbon compounds
585/523
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US 08395010 de Luis et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
U.S. Army Institute of Surgical Research (USAISR)
U.S. Army Medical Research and Materiel Command (USAMRMC)
APPLICANT(S) Javier de Luis (Cambridge, Massachusetts);  Marco Serra (Lucca, Italy);  Timothy Sutherland (Cambridge, Massachusetts);  Liping Sun (North Andover, Massachusetts)
ASSIGNEE(S) FEG Holdings, LLC (Strongsville, Ohio)
INVENTOR(S) Javier de Luis (Cambridge, Massachusetts);  Marco Serra (Lucca, Italy);  Timothy Sutherland (Cambridge, Massachusetts);  Liping Sun (North Andover, Massachusetts)
ABSTRACT The present invention provides devices and methods for treating wounds. The devices may include polymer particles capable of absorbing fluid such as blood. When devices of the invention are exposed to fluid, the fluid may enter the device and cause the polymer particles to swell. Devices of the invention may also apply pressure on wound cavities to stop or restrict the flow of fluid. In some embodiments, the devices may comprise components to facilitate absorption of fluid throughout the device, such as wicking elements and/or multiple compartments. One or more of the devices can be placed directly in the wound cavity, or in a containment structure and then into the wound cavity.
FILED Monday, November 22, 2010
APPL NO 12/952037
ART UNIT 3772 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Surgery: Splint, brace, or bandage
62/46
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US 08395093 Auffinger, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Armaments Center (CCDC AC)
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
APPLICANT(S) Frank Auffinger, III (Hamilton, Ohio);  Michael Richard Maddux (Jamestown, Ohio);  Kristopher Karl Aber (Cincinnati, Ohio);  Brandon Charles Kirby (Morgantown, West Virginia)
ASSIGNEE(S) Cornerstone Research Group, Inc. (Dayton, Ohio)
INVENTOR(S) Frank Auffinger, III (Hamilton, Ohio);  Michael Richard Maddux (Jamestown, Ohio);  Kristopher Karl Aber (Cincinnati, Ohio);  Brandon Charles Kirby (Morgantown, West Virginia)
ABSTRACT The preferred embodiment utilizes metal coated high strain fabric reinforcement including but not limited to fiberglass, cotton fiber, or other materials that can undergo deformation, and various resin or elastomer compounds to create a conductive polymer whose resistivity and resistance remain essentially constant under a strain of approximately 0-150% or more. Additionally, the preferred embodiment utilizes a method of imprinting, depositing, etching, or embossing a design or pattern of conductive metal on fabric used in composites. The use of designs of conductive metals wrapped around a deformable core and the unique features of elastomeric polymers allows for their use as a flexible circuit board, formable heaters, and other various uses.
FILED Tuesday, April 06, 2010
APPL NO 12/754708
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Electric heating
219/543
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US 08395150 Marks et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
Division of Materials Research (DMR)
APPLICANT(S) Tobin J. Marks (Evanston, Illinois);  Antonio Facchetti (Chicago, Illinois);  Lian Wang (Evanston, Illinois);  Myung-Han Yoon (Cambridge, Massachusetts);  Yu Yang (Santa Clara, California)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Tobin J. Marks (Evanston, Illinois);  Antonio Facchetti (Chicago, Illinois);  Lian Wang (Evanston, Illinois);  Myung-Han Yoon (Cambridge, Massachusetts);  Yu Yang (Santa Clara, California)
ABSTRACT Inorganic semiconducting compounds, composites and compositions thereof, and related device structures.
FILED Monday, January 16, 2012
APPL NO 13/351050
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/43
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US 08395298 Rossman
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
APPLICANT(S) Court E. Rossman (Merrimack, New Hampshire)
ASSIGNEE(S) BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire)
INVENTOR(S) Court E. Rossman (Merrimack, New Hampshire)
ABSTRACT The invention provides an actuator apparatus and method where a source provides electrons to a target material wherein electrical work is performed. A beta emission process comprises a source material emitting electrons which are then captured by a target material. The actuator's source vanes rotate within an electric field between the target chutes' walls, generating torque. The principal providing torque and power is the change in energy as a vane gets closer to the outer walls. During the release and capture process, electrical work is performed which, in turn, is transferred into mechanical work in the form of rotation of the rotor. Specific applications include a radioisotope fueled rotary actuator for micro and nano air vehicles employed as the main form of propulsion.
FILED Monday, June 21, 2010
APPL NO 12/819412
ART UNIT 2834 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/309
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US 08395301 Uchino et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Kenji Uchino (State College, Pennsylvania);  Yuan Zhuang (State College, Pennsylvania);  Seyit O Ural (State College, Pennsylvania);  Ahmed Amin (North Attleboro, Massachusetts)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Kenji Uchino (State College, Pennsylvania);  Yuan Zhuang (State College, Pennsylvania);  Seyit O Ural (State College, Pennsylvania);  Ahmed Amin (North Attleboro, Massachusetts)
ABSTRACT A piezoelectric transformer includes a single crystal relaxor ferroelectric element poled along a [0 11] direction and selected from the group consisting of PZN-PT, PMN-PZT, PZN-PT and PMN-PT. The element has two opposed surfaces substantially perpendicular to the [0 11] direction with an input electrode and an output electrode positioned on one surface. The output electrode is isolated from electrical communication with the input electrode. A ground electrode is positioned on the second, opposed surface. Input electrical energy results in piezoelectric change in the element that is mechanically coupled through the element to generate piezoelectric output energy.
FILED Wednesday, December 08, 2010
APPL NO 12/962834
ART UNIT 2837 — Electrical Circuits and Systems
CURRENT CPC
Electrical generator or motor structure
310/357
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US 08395393 Betz et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) James R. Betz (Tucson, Arizona);  Michael D. Ambrose (Vail, Arizona);  Brett A. Anderson (Tucson, Arizona);  Bryan J. Wallace (Oro Valley, Arizona);  Edward G. Robinson (Tucson, Arizona)
ASSIGNEE(S) Raytheon Company (Waltham, Massachusetts)
INVENTOR(S) James R. Betz (Tucson, Arizona);  Michael D. Ambrose (Vail, Arizona);  Brett A. Anderson (Tucson, Arizona);  Bryan J. Wallace (Oro Valley, Arizona);  Edward G. Robinson (Tucson, Arizona)
ABSTRACT A cable testing method includes a tester that includes at least one connector electrically coupled, such as by conductive traces, to a computer. Both ends of the cable are connected to the at least one connector. The computer then sends a signal to one of the conductive traces of the conductor, at one of the ends of the cable, while at the same time monitoring for a signal at the other contacts of the conductor that are in contact with conductive traces of the cable. The process of sending power while monitoring may then be repeated for other of the conductive traces of the cable, for example until substantially all of the conductive traces of the cable are tested. The process of testing multiple of the conductive traces sequentially may be performed automatically by the computer, allowing performance of the cable to be tested quickly, completely, and accurately.
FILED Tuesday, February 02, 2010
APPL NO 12/698461
ART UNIT 2858 — Printing/Measuring and Testing
CURRENT CPC
Electricity: Measuring and testing
324/539
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US 08395496 Joshi et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Shiv P Joshi (Rancho Palos Verdes, California);  Cesar Del Solar (Pasadena, California)
ASSIGNEE(S)
INVENTOR(S) Shiv P Joshi (Rancho Palos Verdes, California);  Cesar Del Solar (Pasadena, California)
ABSTRACT A miniature modular wireless sensor unit. The unit includes three separate easily assembled and disassembled modules: a processor-communications module, a battery pack module, and a swappable sensor module. Preferred embodiments utilize Bluetooth radio communication technology to communicate sensor data. The total size of preferred embodiments is 1.380 inch×0.940 inch×0.540 inch. Preferred embodiments are easily programmed and calibrated by lay people to automatically communicate sensor information via Bluetooth techniques to a personal computer, laptop or similar equipment. A wide variety of sensors can be utilized with the standard sensor unit. Various battery pack modules are provided to match battery power with needs.
FILED Thursday, March 27, 2008
APPL NO 12/079752
ART UNIT 2685 — Selective Communication
CURRENT CPC
Communications: Electrical
340/539.100
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US 08395505 Hadley et al.
FUNDED BY
Department of Defense (DOD)
Defense MicroElectronics Activity (DMEA)
APPLICANT(S) Mark Alfred Hadley (Newark, California);  James Harold Atherton (Morgan Hill, California);  Jay Tu (Pleasanton, California);  Edward John Boling (Fremont, California);  John Stephen Smith (San Jose, California)
ASSIGNEE(S) Alien Technology Corporation (Morgan Hill, California)
INVENTOR(S) Mark Alfred Hadley (Newark, California);  James Harold Atherton (Morgan Hill, California);  Jay Tu (Pleasanton, California);  Edward John Boling (Fremont, California);  John Stephen Smith (San Jose, California)
ABSTRACT Methods and apparatuses for selecting a subset of RFID tags are provided in some embodiments. These methods and apparatuses utilize the susceptibility to light by persistent nodes found in passive tags. Light can be used to intentionally reduce persistence times in a particular subset tags or even an individual tag. Then, persistent nodes can be used as a selection criterion to distinguish previously illuminated tags from non-illuminated tags. In other embodiments, a power circuit receives a RF input source and generates a direct current (DC) output voltage. The circuit includes a bias circuit to supply a gate to source bias, which is independent of the DC output voltage. The circuit further includes a voltage multiplier circuit that is coupled to the bias circuit. The voltage multiplier circuit has MOS transistors with one transistor to receive the gate to source bias.
FILED Tuesday, April 07, 2009
APPL NO 12/420009
ART UNIT 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory
CURRENT CPC
Communications: Electrical
340/572.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08395559 Josypenko
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Michael J. Josypenko (Norwich, Connecticut)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Michael J. Josypenko (Norwich, Connecticut)
ABSTRACT A forty five degree polarized antenna having grid layers wrapped around a vertically polarized dipole, or grids wrapped internally or externally around a vertically polarized bicone antenna, and having grid segments separated by capacitors that can attenuate, remove or minimize circumferential resonances that appear due to the presence of the grids and reduce the nulling effects from reflections from the innermost grid layer.
FILED Monday, September 13, 2010
APPL NO 12/880346
ART UNIT 2821 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC
Communications: Radio wave antennas
343/773
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US 08395768 Li et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Zhiyong Li (Redwood City, California);  David A. Fattal (Mountain View, California);  Jingjing Li (Palo Alto, California);  R. Stanley Williams (Portola Valley, California)
ASSIGNEE(S) Hewlett-Packard Development Company, L.P. (Houston, Texas)
INVENTOR(S) Zhiyong Li (Redwood City, California);  David A. Fattal (Mountain View, California);  Jingjing Li (Palo Alto, California);  R. Stanley Williams (Portola Valley, California)
ABSTRACT A scattering spectroscopy apparatus, system and method employ guided mode resonance (GMR) and a GMR grating. The apparatus includes a GMR grating having a subwavelength grating, and an optical detector configured to receive a portion of a scattered signal produced by an interaction between an excitation signal and an analyte associated with a surface of the GMR grating. A propagation direction of the received portion of the scattered signal is substantially different from a propagation direction of a GMR-coupled portion of the excitation signal within the GMR grating. The system includes the apparatus and an optical source. The method includes exciting a GMR in a GMR grating, interacting a GMR-coupled portion of the excitation signal with an analyte to produce a scattered signal and detecting a portion of the scattered signal.
FILED Friday, April 30, 2010
APPL NO 12/772161
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/301
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US 08395770 Hug et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) William F. Hug (Altadena, California);  Ray D. Reid (Glendora, California);  Rohit Bhartia (Pasadena, California)
ASSIGNEE(S) Photon Systems (Covina, California)
INVENTOR(S) William F. Hug (Altadena, California);  Ray D. Reid (Glendora, California);  Rohit Bhartia (Pasadena, California)
ABSTRACT Spectroscopic chemical analysis methods and apparatus are disclosed which employ deep ultraviolet (e.g. in the 200 nm to 300 nm spectral range) electron beam pumped wide bandgap semiconductor lasers, incoherent wide bandgap semiconductor light emitting devices, and hollow cathode metal ion lasers to perform non-contact, non-invasive detection of unknown chemical analytes. These deep ultraviolet sources enable dramatic size, weight and power consumption reductions of chemical analysis instruments. Chemical analysis instruments employed in some embodiments include capillary and gel plane electrophoresis, capillary electrochromatography, high performance liquid chromatography, flow cytometry, flow cells for liquids and aerosols, and surface detection instruments. In some embodiments, Raman spectroscopic detection methods and apparatus use ultra-narrow-band angle tuning filters, acousto-optic tuning filters, and temperature tuned filters to enable ultra-miniature analyzers for chemical identification. In some embodiments Raman analysis is conducted along with photoluminescence spectroscopy (i.e. fluorescence and/or phosphorescence spectroscopy) to provide high levels of sensitivity and specificity in the same instrument.
FILED Friday, August 21, 2009
APPL NO 12/545772
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/317
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08395901 Tour et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) James M. Tour (Bellaire, Texas);  Yubao Li (Milpitas, California);  Alexander Sinitskiy (Ryazan, Russian Federation);  Lin Zhong (Houston, Texas);  Mian Dong (Houston, Texas);  Jun Yao (Houston, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) James M. Tour (Bellaire, Texas);  Yubao Li (Milpitas, California);  Alexander Sinitskiy (Ryazan, Russian Federation);  Lin Zhong (Houston, Texas);  Mian Dong (Houston, Texas);  Jun Yao (Houston, Texas)
ABSTRACT Vertically-stacked electronic devices having conductive carbon films are disclosed. The vertically-stacked devices exhibit non-linear current-versus-voltage response over a voltage sweep range in various embodiments. The vertically-stacked devices may be assembled into arrays where the vertically-stacked devices may be electrically addressed independently of one another. Uses of the vertically-stacked electronic devices and arrays as two-terminal memory devices, logic units, and sensors are disclosed. Crossbar arrays of vertically-stacked electronic devices having conductive carbon films and nanowire electrodes are disclosed.
FILED Thursday, November 13, 2008
APPL NO 12/270246
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/735
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08395947 Harvard et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Qawi I. Harvard (Santa Clara, California);  Robert J. Drost (Los Altos, California);  R. Jacob Baker (Boise, Idaho)
ASSIGNEE(S) Oracle America, Inc. (Redwood Shores, California)
INVENTOR(S) Qawi I. Harvard (Santa Clara, California);  Robert J. Drost (Los Altos, California);  R. Jacob Baker (Boise, Idaho)
ABSTRACT A memory device with increased communication bandwidth is described. In this memory device, control logic routes data signals from a memory array using inactive bitlines in response to a read command. These data signals are then placed on an adjacent unused input/output (I/O) line or routing channel, as opposed to a proximate I/O line that is in use. For example, unused bitlines located on the top and bottom of the memory array may be used to route data signals to adjacent local I/O lines. In particular, the data signals can be placed on unused local I/O lines which are associated with adjacent bitline sense amplifiers. The resulting increased communication bandwidth can overcome the constraints imposed by the limited number of local I/O lines in the memory device without appreciably increasing the chip size, power consumption, or cost.
FILED Friday, April 08, 2011
APPL NO 13/082785
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/189.150
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08396053 Giles et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) James Ryan Giles (Yorktown Heights, New York);  Rohit Wagle (Elmsford, New York);  Xiaolan J. Zhang (Champaign, Illinois)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) James Ryan Giles (Yorktown Heights, New York);  Rohit Wagle (Elmsford, New York);  Xiaolan J. Zhang (Champaign, Illinois)
ABSTRACT An illustrative embodiment of the present invention includes a method for routing at least one packet from at least one source node to at least one destination node, each node is operatively coupled to a given packet switch within a plurality of packet switches operatively coupled to a given circuit switch. The method includes a step of establishing one or more Virtual Local Area Networks (VLANs). Each VLAN comprising a subset of the plurality of packet switches operatively coupled to the given circuit switch. At least one of the one or more VLANs comprises the at least one packet switch to which the source and destination nodes are operatively coupled. The method also includes a step of routing the at least one packet from the source node to the destination node over at least one loop-free path comprised of one or more packet switches within a given VLAN.
FILED Thursday, April 24, 2008
APPL NO 12/108861
ART UNIT 2477 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/352
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US 08396136 Pezeshkian
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
Space and Naval Warfare Systems Center (SPAWAR)
APPLICANT(S) Narek Pezeshkian (Glendale, California)
ASSIGNEE(S) The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Narek Pezeshkian (Glendale, California)
ABSTRACT A system includes a first device having a first transceiver and a first device electrode pair connected to the first transceiver, and a second device having a second transceiver and a second device electrode pair connected to the second transceiver. The second device electrode pair is located relative to the first device electrode pair such that the first device electrode pair and the second device electrode pair form a capacitive network. The first transceiver and second transceiver are each configured to receive a plurality of bits, encode each bit of the plurality of bits, and DC balance and transmit each of the plurality of encoded bits over the capacitive network. Methods for use with the system are provided for encoding and transmitting data, as well as receiving and decoding the encoded data.
FILED Wednesday, July 22, 2009
APPL NO 12/507324
ART UNIT 2632 — Digital Communications
CURRENT CPC
Pulse or digital communications
375/257
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US 08396181 Naranjo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Brian Naranjo (Fullerton, California);  James Gimzewski (Santa Monica, California);  Seth Putterman (Los Angeles, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Brian Naranjo (Fullerton, California);  James Gimzewski (Santa Monica, California);  Seth Putterman (Los Angeles, California)
ABSTRACT Gently heating a pyroelectric crystal in a deuterated atmosphere can generate fusion under desktop conditions. The electrostatic field of the crystal is used to generate and accelerate a deuteron beam (>100 keV and >4 nA), which, upon striking a deuterated target, produces a neutron flux over 400 times the background level. The presence of neutrons within the target is confirmed by pulse shape analysis and proton recoil spectroscopy. Several elements of the system may be modified, including the configuration of the crystal or crystals, the composition of the surrounding environment and the target, the use of multiple probe tips, and the composition of the probe tip.
FILED Tuesday, May 08, 2007
APPL NO 11/745556
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Induced nuclear reactions: Processes, systems, and elements
376/114
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US 08396293 Korah et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S) Thommen Korah (Marina Del Rey, California);  Swarup S. Medasani (Thousand Oaks, California);  Yuri Owechko (Newbury Park, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Thommen Korah (Marina Del Rey, California);  Swarup S. Medasani (Thousand Oaks, California);  Yuri Owechko (Newbury Park, California)
ABSTRACT A method of recognizing geometrically salient objects from sensed data points collected in a 3D environment includes using a sensor that collects a plurality of sensed data points each having spatial coordinate information in three dimensions x, y and z, populating a strip histogram grid having a plurality of strips, each strip having a z, dx and dy dimensions, wherein dx is a portion of an x dimension and dy is a portion of a y dimension of the strip histogram grid, by assigning each sensed data point to a strip that has x, y and z dimensions that encompass the spatial coordinate information of the respective assigned sensed data point, and segmenting the strip histogram grid into a plurality of segmented regions, each segmented region comprising one strip or a group of neighboring strips having similar attributes.
FILED Tuesday, December 22, 2009
APPL NO 12/644751
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/171
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US 08396337 Kroemer et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
APPLICANT(S) Herbert Kroemer (Santa Barbara, California);  John E. Bowers (Santa Barbara, California);  Ming-Chun Tien (Goleta, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Herbert Kroemer (Santa Barbara, California);  John E. Bowers (Santa Barbara, California);  Ming-Chun Tien (Goleta, California)
ABSTRACT By introducing magneto-optical garnets with high Faraday rotation and low optical loss in a ring resonator, a nonreciprocal phase shift is generated to split the resonance wavelengths of clockwise and counter-clockwise modes under magnetic field. There are three main applications based on this nonreciprocal effect, optical isolators, optical circulators, and tunable optical filters. The concept of the tunable filters and the design of optical isolators for TE and TM modes are described in the paper. With proper optical ring isolator configurations, optical circulators can be realized.
FILED Wednesday, June 30, 2010
APPL NO 12/827733
ART UNIT 2874 — Optics
CURRENT CPC
Optical waveguides
385/27
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US 08396870 Birdwell et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Space and Missile Defense Command (SMDC)
U.S. Army Space and Missile Defense Command (USASMDC)
APPLICANT(S) J. Douglas Birdwell (Oak Ridge, Tennessee);  Tse-Wei Wang (Oak Ridge, Tennessee);  David J. Icove (Knoxville, Tennessee);  Sally P. Horn (Knoxville, Tennessee);  Roger Horn (Knoxville, Tennessee);  Mark S. Rader (Huntsville, Alabama);  Dale V. Stansberry (Oak Ridge, Tennessee)
ASSIGNEE(S) University of Tennessee Research Foundation (Knoxville, Tennessee)
INVENTOR(S) J. Douglas Birdwell (Oak Ridge, Tennessee);  Tse-Wei Wang (Oak Ridge, Tennessee);  David J. Icove (Knoxville, Tennessee);  Sally P. Horn (Knoxville, Tennessee);  Roger Horn (Knoxville, Tennessee);  Mark S. Rader (Huntsville, Alabama);  Dale V. Stansberry (Oak Ridge, Tennessee)
ABSTRACT Method and apparatus for predicting properties of a target object comprise application of a search manager for analyzing parameters of a plurality of databases for a plurality of objects, the databases comprising an electrical, electromagnetic, acoustic spectral database (ESD), a micro-body assemblage database (MAD) and a database of image data whereby the databases store data objects containing identifying features, source information and information on site properties and context including time and frequency varying data. The method comprises application of multivariate statistical analysis and principal component analysis in combination with content-based image retrieval for providing two-dimensional attributes of three dimensional objects, for example, via preferential image segmentation using a tree of shapes and to predict further properties of objects by means of k-means clustering and related methods. By way of example, a fire event and residual objects may be located and qualified such that, for example, properties of the residual objects may be qualified, for example, via black body radiation and micro-body databases including charcoal assemblages.
FILED Friday, June 25, 2010
APPL NO 12/823303
ART UNIT 2168 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/737
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08396958 Hilferty
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) Edward L. Hilferty (Glenolden, Pennsylvania)
ASSIGNEE(S) The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) Edward L. Hilferty (Glenolden, Pennsylvania)
ABSTRACT Multiple personal computers are each situated aboard its own ship and are each communicatively connected to an electronic depository of information for purposes of effecting real time management of engines and other shipboard machinery. Information is electronically communicated back and forth between each onboard computer and the electronic depository, such as via File Transfer Protocol (FTP), e-mail or compact disk (CD). The electronic depository takes information from all of the onboard computers, and each onboard computer records information including that which is entered therein by a user and that which derives from the electronic depository. Each onboard computer executes import and export routines for communicating with the electronic depository, and executes start-up routines for displaying user-interactive formal screens that are individually tailored for the user's input and viewing of particular types of information, such as involving maintenance, repair, logistics, inspection and/or operation of the machinery.
FILED Tuesday, December 02, 2003
APPL NO 10/729268
ART UNIT 2478 — Multiplex and VoIP
CURRENT CPC
Electrical computers and digital processing systems: Multicomputer data transferring
79/224
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US 08397130 Clark et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Lawrence T. Clark (Phoenix, Arizona);  Dan W. Patterson (Scottsdale, Arizona);  Xiaoyin Yao (Chandler, Arizona)
ASSIGNEE(S) Arizona Board of Regents for and on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Lawrence T. Clark (Phoenix, Arizona);  Dan W. Patterson (Scottsdale, Arizona);  Xiaoyin Yao (Chandler, Arizona)
ABSTRACT Embodiments of circuits and methods for circuits for the detection of soft errors in cache memories are described herein. Other embodiments and related methods and examples are also described herein.
FILED Wednesday, November 25, 2009
APPL NO 12/626479
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/763
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08397133 Clark et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
APPLICANT(S) Lawrence T. Clark (Phoenix, Arizona);  Dan W. Patterson (Scottsdale, Arizona);  Xiaoyin Yao (Albuquerque, New Mexico);  David Pettit (Gilbert, Arizona);  Rahul Shringarpure (Calabasas, California)
ASSIGNEE(S) Arizona Board of Regents for and on behalf of Arizona State University (Scottsdale, Arizona)
INVENTOR(S) Lawrence T. Clark (Phoenix, Arizona);  Dan W. Patterson (Scottsdale, Arizona);  Xiaoyin Yao (Albuquerque, New Mexico);  David Pettit (Gilbert, Arizona);  Rahul Shringarpure (Calabasas, California)
ABSTRACT Embodiments of circuits and method for dual redundant register files with error detection and correction mechanisms are described herein. Other embodiments and related examples are also described herein.
FILED Wednesday, November 25, 2009
APPL NO 12/626488
ART UNIT 2113 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/766
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08397209 Kirby, Jr.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
APPLICANT(S) James Kirby, Jr. (Columbia, Maryland)
ASSIGNEE(S) The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia)
INVENTOR(S) James Kirby, Jr. (Columbia, Maryland)
ABSTRACT A software application to be used in an environment includes environmental, behavioral, design, and run-time model creating portions. The environmental portion includes a first set of attributes of the environment, wherein each of the first set of attributes has a declaration and a decomposition into environmental classes. The behavioral portion describes behavior of the software application at a boundary of the software application and the environment, wherein the behavioral model includes a second set of attributes, and each of the second set of attributes has at least one of a declaration and function. The design portion includes a first decomposition of the second set of attributes into a first plurality of groups. The run-time portion includes a second decomposition of the second set of attributes into a second plurality of groups, wherein the run-time model can record the decomposition of the software application into run-time components.
FILED Thursday, November 17, 2005
APPL NO 11/288055
ART UNIT 2192 — Interprocess Communication and Software Development
CURRENT CPC
Data processing: Software development, installation, and management
717/104
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Energy (DOE) 

US 08393066 Montesanti et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Richard C. Montesanti (Pleasanton, California);  Jeffrey L. Klingmann (Livermore, California);  Richard M. Seugling (Discovery Bay, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Richard C. Montesanti (Pleasanton, California);  Jeffrey L. Klingmann (Livermore, California);  Richard M. Seugling (Discovery Bay, California)
ABSTRACT An apparatus for assembling a miniaturized device includes a manipulator system including six manipulators operable to position and orient components of the miniaturized device with submicron precision and micron-level accuracy. The manipulator system includes a first plurality of motorized axes, a second plurality of manual axes, and force and torque and sensors. Each of the six manipulators includes at least one translation stage, at least one rotation stage, tooling attached to the at least one translation stage or the at least one rotation stage, and an attachment mechanism disposed at a distal end of the tooling and operable to attach at least a portion of the miniaturized device to the tooling. The apparatus also includes an optical coordinate-measuring machine (OCMM) including a machine-vision system, a laser-based distance-measuring probe, and a touch probe. The apparatus also includes an operator control system coupled to the manipulator system and the OCMM.
FILED Friday, February 19, 2010
APPL NO 12/709321
ART UNIT 3635 — Static Structures, Supports and Furniture
CURRENT CPC
Metal working
029/407.40
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08393707 Cudzinovic et al.
FUNDED BY
Department of Energy (DOE)
Office of Energy Efficiency and Renewable Energy (EERE)
APPLICANT(S) Michael Cudzinovic (Sunnyvale, California);  Thomas Pass (San Jose, California);  Rob Rogers (Santa Clara, California);  Ray-Hon Sun (Palo Alto, California);  Sheng Sun (Foster City, California);  Ben Wahlstrom (Albany, Oregon);  Dennis Jason Fuhrman (Corvallis, Oregon);  Kyle David Altendorf (Corvallis, Oregon)
ASSIGNEE(S) SunPower Corporation (San Jose, California)
INVENTOR(S) Michael Cudzinovic (Sunnyvale, California);  Thomas Pass (San Jose, California);  Rob Rogers (Santa Clara, California);  Ray-Hon Sun (Palo Alto, California);  Sheng Sun (Foster City, California);  Ben Wahlstrom (Albany, Oregon);  Dennis Jason Fuhrman (Corvallis, Oregon);  Kyle David Altendorf (Corvallis, Oregon)
ABSTRACT A substrate patterning method including the steps of spraying ink on a surface of a substrate, the spraying of the ink resulting in an overspray of excess ink past an edge of the substrate; changing a temperature of the excess ink to cause a change in a viscosity of the excess ink; and removing the excess ink having the changed viscosity.
FILED Tuesday, August 24, 2010
APPL NO 12/862086
ART UNIT 2853 — Printing/Measuring and Testing
CURRENT CPC
Incremental printing of symbolic information
347/17
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394298 Kim et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Yu Seung Kim (Los Alamos, New Mexico);  Kwan-Soo Lee (Blacksburg, Virginia);  Tommy Q. T. Rockward (Rio Rancho, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Yu Seung Kim (Los Alamos, New Mexico);  Kwan-Soo Lee (Blacksburg, Virginia);  Tommy Q. T. Rockward (Rio Rancho, New Mexico)
ABSTRACT Compositions, and methods of making thereof, comprising from about 1% to about 5% of a perfluorinated sulfonic acid ionomer or a hydrocarbon-based ionomer; and from about 95% to about 99% of a solvent, said solvent consisting essentially of a polyol; wherein said composition is substantially free of water and wherein said ionomer is uniformly dispersed in said solvent.
FILED Monday, June 13, 2011
APPL NO 13/158818
ART UNIT 1761 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Compositions
252/519.330
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394312 Sommer et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Sandia National Laboratories (SNL)
Federally Funded Research and Development Center (FFRDC)
Operated by National Technology and Engineering Solutions of Sandia, LLC (NTESS) at Albuquerque, NM
APPLICANT(S) Gregory J. Sommer (Livermore, California);  Anson V. Hatch (Tracy, California);  Ying-Chih Wang (Pleasanton, California);  Anup K. Singh (Danville, California);  Ronald F. Renzi (Tracy, California);  Mark R. Claudnic (Livermore, California)
ASSIGNEE(S) Sandia Corporation (Albuquerque, New Mexico)
INVENTOR(S) Gregory J. Sommer (Livermore, California);  Anson V. Hatch (Tracy, California);  Ying-Chih Wang (Pleasanton, California);  Anup K. Singh (Danville, California);  Ronald F. Renzi (Tracy, California);  Mark R. Claudnic (Livermore, California)
ABSTRACT Methods for making a microfluidic device according to embodiments of the present invention include defining˜cavity. Polymer precursor solution is positioned in the cavity, and exposed to light to begin the polymerization process and define a microchannel. In some embodiments, after the polymerization process is partially complete, a solvent rinse is performed, or fresh polymer precursor introduced into the microchannel. This may promote removal of unpolymerized material from the microchannel and enable smaller feature sizes. The polymer precursor solution may contain an iniferter. Polymerized features therefore may be capped with the iniferter, which is photoactive. The iniferter may aid later binding of a polyacrylamide gel to the microchannel surface.
FILED Tuesday, September 20, 2011
APPL NO 13/237027
ART UNIT 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding
CURRENT CPC
Plastic and nonmetallic article shaping or treating: Processes
264/494
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394350 Aines
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Roger D. Aines (Livermore, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Roger D. Aines (Livermore, California)
ABSTRACT A method for separating CO2 from gas mixtures uses a slurried media impregnated with buffer compounds and coating the solid media with a catalyst or enzyme that promotes the transformation of CO2 to carbonic acid. Buffer sorbent pebbles with a catalyst or enzyme coating are provided for rapid separation of CO2 from gas mixtures.
FILED Wednesday, May 19, 2010
APPL NO 12/783394
ART UNIT 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Chemistry of inorganic compounds
423/226
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394351 Valdez et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Carlos A. Valdez (San Ramon, California);  Joe H. Satcher, Jr. (Patterson, California);  Roger D. Aines (Livermore, California);  Sarah E. Baker (Pleasanton, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Carlos A. Valdez (San Ramon, California);  Joe H. Satcher, Jr. (Patterson, California);  Roger D. Aines (Livermore, California);  Sarah E. Baker (Pleasanton, California)
ABSTRACT Various methods and structures of complexes and molecules are described herein related to a zinc-centered catalyst for removing carbon dioxide from atmospheric or aqueous environments. According to one embodiment, a method for creating a tris(triazolyl)pentaerythritol molecule includes contacting a pentaerythritol molecule with a propargyl halide molecule to create a trialkyne molecule, and contacting the trialkyne molecule with an azide molecule to create the tris(triazolyl)pentaerythritol molecule. In another embodiment, a method for creating a tris(imidazolyl)pentaerythritol molecule includes alkylating an imidazole 2-carbaldehyde molecule to create a monoalkylated aldehyde molecule, reducing the monoalkylated aldehyde molecule to create an alcohol molecule, converting the alcohol molecule to create an alkyl halide molecule using thionyl halide, and reacting the alkyl halide molecule with a pentaerythritol molecule to create a tris(imidazolyl)pentaerythritol molecule. In another embodiment, zinc is bound to the tris(triazolyl)pentaerythritol molecule to create a zinc-centered tris(triazolyl)pentaerythritol catalyst for removing carbon dioxide from atmospheric or aqueous environments.
FILED Tuesday, May 25, 2010
APPL NO 12/787356
ART UNIT 1621 — Organic Chemistry
CURRENT CPC
Chemistry of inorganic compounds
423/226
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394352 Chen et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Fanglin Chen (Irmo, South Carolina);  Qiang Liu (Columbia, South Carolina)
ASSIGNEE(S) University of South Carolina (Columbia, South Carolina)
INVENTOR(S) Fanglin Chen (Irmo, South Carolina);  Qiang Liu (Columbia, South Carolina)
ABSTRACT Methods are generally disclosed for synthesis of porous particles from a solution formed from a leaving agent, a surfactant, and a soluble metal salt in a solvent. The surfactant congregates to form a nanoparticle core such that the metal salt forms about the nanoparticle core to form a plurality of nanoparticles. The solution is heated such that the leaving agent forms gas bubbles in the solution, and the plurality of nanoparticles congregate about the gas bubbles to form a porous particle. The porous particles are also generally disclosed and can include a particle shell formed about a core to define an average diameter from about 0.5 μm to about 50 μm. The particle shell can be formed from a plurality of nanoparticles having an average diameter of from about 1 nm to about 50 nm and defined by a metal salt formed about a surfactant core.
FILED Wednesday, December 09, 2009
APPL NO 12/634092
ART UNIT 1788 — Miscellaneous Articles, Stock Material
CURRENT CPC
Chemistry of inorganic compounds
423/265
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US 08394544 Chick et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Lawrence A. Chick (West Richland, Washington);  Vincent L. Sprenkle (Richland, Washington);  Michael R. Powell (Kennewick, Washington);  Kerry D. Meinhardt (Kennewick, Washington);  Greg A. Whyatt (West Richland, Washington)
ASSIGNEE(S) Battelle Memorial Institute (Richland, Washington)
INVENTOR(S) Lawrence A. Chick (West Richland, Washington);  Vincent L. Sprenkle (Richland, Washington);  Michael R. Powell (Kennewick, Washington);  Kerry D. Meinhardt (Kennewick, Washington);  Greg A. Whyatt (West Richland, Washington)
ABSTRACT The present invention is a Solid Oxide Fuel Cell Reforming Power System that utilizes adiabatic reforming of reformate within this system. By utilizing adiabatic reforming of reformate within the system the system operates at a significantly higher efficiency than other Solid Oxide Reforming Power Systems that exist in the prior art. This is because energy is not lost while materials are cooled and reheated, instead the device operates at a higher temperature. This allows efficiencies higher than 65%.
FILED Friday, May 09, 2008
APPL NO 12/118353
ART UNIT 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/425
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US 08394605 Wang et al.
FUNDED BY
Department of Energy (DOE)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
APPLICANT(S) Jiangyun Wang (Beijing, China PRC);  Peter G. Schultz (La Jolla, California)
ASSIGNEE(S) The Scripps Research Institute (La Jolla, California)
INVENTOR(S) Jiangyun Wang (Beijing, China PRC);  Peter G. Schultz (La Jolla, California)
ABSTRACT The invention relates to orthogonal pairs of tRNAs and aminoacyl-tRNA synthetase that can incorporate the unnatural amino acid phenylselenocysteine into proteins produced in eubacterial host cells such as E. coli. The invention provides, for example but not limited to, novel orthogonal aminoacyl-tRNA synthetases, polynucleotides encoding the novel sythetases molecules, methods for identifying and making the novel synthetases, methods for producing containing the unnatural amino acid phenylselenocysteine and translation systems. The invention further provides methods for producing modified proteins (e.g., lapidated proteins) through targeted modification of the phenylselenocysteine residue in a protein.
FILED Friday, June 08, 2012
APPL NO 13/492240
ART UNIT 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/68.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394611 Dale et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Bruce E. Dale (Mason, Michigan);  Lee R. Lynd (Meriden, New Hampshire);  Mark Laser (Norwich, Vermont)
ASSIGNEE(S) Board of Trustees of Michigan State University (East Lansing, Michigan)
INVENTOR(S) Bruce E. Dale (Mason, Michigan);  Lee R. Lynd (Meriden, New Hampshire);  Mark Laser (Norwich, Vermont)
ABSTRACT A process for the treatment of biomass to render structural carbohydrates more accessible and/or digestible using concentrated ammonium hydroxide with or without anhydrous ammonia addition, is described. The process preferably uses steam to strip ammonia from the biomass for recycling. The process yields of monosaccharides from the structural carbohydrates are good, particularly as measured by the enzymatic hydrolysis of the structural carbohydrates. The monosaccharides are used as animal feeds and energy sources for ethanol production.
FILED Monday, April 30, 2007
APPL NO 12/226763
ART UNIT 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Chemistry: Molecular biology and microbiology
435/105
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US 08394640 Golovchenko et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S) Jene A. Golovchenko (Lexington, Massachusetts);  Jiali Li (Fayetteville, Arkansas);  Derek Stein (Delft, Netherlands);  Marc H. Gershow (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jene A. Golovchenko (Lexington, Massachusetts);  Jiali Li (Fayetteville, Arkansas);  Derek Stein (Delft, Netherlands);  Marc H. Gershow (Cambridge, Massachusetts)
ABSTRACT The invention features methods for evaluating the conformation of a polymer, for example, for determining the conformational distribution of a plurality of polymers and to detect binding or denaturation events. The methods employ a nanopore which the polymer, e.g., a nucleic acid, traverses. As the polymer traverses the nanopore, measurements of transport properties of the nanopore yield data on the conformation of the polymer.
FILED Monday, December 06, 2010
APPL NO 12/961021
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/86
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US 08394664 Nicholas et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Department of Energy (DOE)
Office of Science (DOE-SC)
Oak Ridge National Laboratory (ORNL)
Federally Funded Research and Development Center (FFRDC)
Operated by UT-Battelle, LLC (UTB) at Oak Ridge, TN
APPLICANT(S) Nolan Walker Nicholas (Houston, Texas);  W. Carter Kittrell (Houston, Texas);  Myung Jong Kim (Houston, Texas);  Howard K. Schmidt (Cypress, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) Nolan Walker Nicholas (Houston, Texas);  W. Carter Kittrell (Houston, Texas);  Myung Jong Kim (Houston, Texas);  Howard K. Schmidt (Cypress, Texas)
ABSTRACT A method for forming nanotube electrical devices, arrays of nanotube electrical devices, and device structures and arrays of device structures formed by the methods. Various methods of the present invention allow creation of semiconducting and/or conducting devices from readily grown SWNT carpets rather than requiring the preparation of a patterned growth channel and takes advantage of the self-controlling nature of these carpet heights to ensure a known and controlled channel length for reliable electronic properties as compared to the prior methods.
FILED Friday, February 02, 2007
APPL NO 11/910522
ART UNIT 2811 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/99
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US 08394706 Nuzzo et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of Energy (DOE)
Office of Science (DOE-SC)
Materials Sciences and Engineering Division (MSE)
APPLICANT(S) Ralph G. Nuzzo (Champaign, Illinois);  John A. Rogers (Champaign, Illinois);  Etienne Menard (Durham, North Carolina);  Keon Jae Lee (Tokyo, Japan);  Dahl-Young Khang (Urbana, Illinois);  Yugang Sun (Westmont, Illinois);  Matthew Meitl (Raleigh, North Carolina);  Zhengtao Zhu (Rapid City, South Dakota);  Heung Cho Ko (Urbana, Illinois);  Shawn Mack (Goleta, California)
ASSIGNEE(S) The Board of Trustees of the University of Illinois (Urbana, Illinois)
INVENTOR(S) Ralph G. Nuzzo (Champaign, Illinois);  John A. Rogers (Champaign, Illinois);  Etienne Menard (Durham, North Carolina);  Keon Jae Lee (Tokyo, Japan);  Dahl-Young Khang (Urbana, Illinois);  Yugang Sun (Westmont, Illinois);  Matthew Meitl (Raleigh, North Carolina);  Zhengtao Zhu (Rapid City, South Dakota);  Heung Cho Ko (Urbana, Illinois);  Shawn Mack (Goleta, California)
ABSTRACT The present invention provides a high yield pathway for the fabrication, transfer and assembly of high quality printable semiconductor elements having selected physical dimensions, shapes, compositions and spatial orientations. The compositions and methods of the present invention provide high precision registered transfer and integration of arrays of microsized and/or nanosized semiconductor structures onto substrates, including large area substrates and/or flexible substrates. In addition, the present invention provides methods of making printable semiconductor elements from low cost bulk materials, such as bulk silicon wafers, and smart-materials processing strategies that enable a versatile and commercially attractive printing-based fabrication platform for making a broad range of functional semiconductor devices.
FILED Tuesday, October 11, 2011
APPL NO 13/270954
ART UNIT 2823 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/458
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US 08394708 Grier et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) David G. Grier (New York, New York);  Yael Roichman (New York, New York);  Weining Man (Princeton, New Jersey);  Paul Michael Chaikin (Pennington, New Jersey);  Paul Joseph Steinhardt (Princeton, New Jersey)
ASSIGNEE(S) New York University (New York, New York);  The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) David G. Grier (New York, New York);  Yael Roichman (New York, New York);  Weining Man (Princeton, New Jersey);  Paul Michael Chaikin (Pennington, New Jersey);  Paul Joseph Steinhardt (Princeton, New Jersey)
ABSTRACT A method and system for assembling a quasicrystalline heterostructure. A plurality of particles is provided with desirable predetermined character. The particles are suspended in a medium, and holographic optical traps are used to position the particles in a way to achieve an arrangement which provides a desired property.
FILED Friday, June 17, 2011
APPL NO 13/163460
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/479
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US 08395079 Demos et al.
FUNDED BY
Department of Energy (DOE)
National Nuclear Security Administration (NNSA)
Lawrence Livermore National Laboratory (LLNL)
Federally Funded Research and Development Center (FFRDC)
Operated by Lawrence Livermore National Security LLC (LLNS) at Livermore, CA
APPLICANT(S) Stavros G. Demos (Livermore, California);  Alexander M. Rubenchik (Livermore, California);  Raluca A. Negres (Pleasanton, California)
ASSIGNEE(S) Lawrence Livermore National Security, LLC (Livermore, California)
INVENTOR(S) Stavros G. Demos (Livermore, California);  Alexander M. Rubenchik (Livermore, California);  Raluca A. Negres (Pleasanton, California)
ABSTRACT A method of repairing damage in an optical element includes providing a laser system including at least one optical element having a coating layer having an incident light surface and directing a laser pulse from the laser system to impinge on the incident light surface. The method also includes sustaining damage to a portion of the incident light surface and melting the damaged portion of the incident light surface and a region adjacent to the damaged portion. The method further includes flowing material from the region adjacent the damaged portion to the damaged portion and solidifying the material in the damaged portion and the region adjacent to the damaged portion.
FILED Monday, July 12, 2010
APPL NO 12/834706
ART UNIT 2823 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies
CURRENT CPC
Electric heating
219/121.600
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08395123 Dattelbaum et al.
FUNDED BY
Department of Energy (DOE)
Los Alamos National Security, LLC (LANS)
National Nuclear Security Administration (NNSA)
Los Alamos National Laboratory (LANL)
Federally Funded Research and Development Center (FFRDC)
Operated by Triad National Security, LLC (TRIAD) at Los Alamos, NM
APPLICANT(S) Andrew M. Dattelbaum (Los Alamos, New Mexico);  Gautam Gupta (Los Alamos, New Mexico);  Juan G. Duque (Los Alamos, New Mexico);  Stephen K. Doorn (Los Alamos, New Mexico);  Christopher E. Hamilton (Los Alamos, New Mexico);  Kimberly A. DeFriend Obrey (Los Alamos, New Mexico)
ASSIGNEE(S) Los Alamos National Security, LLC (Los Alamos, New Mexico)
INVENTOR(S) Andrew M. Dattelbaum (Los Alamos, New Mexico);  Gautam Gupta (Los Alamos, New Mexico);  Juan G. Duque (Los Alamos, New Mexico);  Stephen K. Doorn (Los Alamos, New Mexico);  Christopher E. Hamilton (Los Alamos, New Mexico);  Kimberly A. DeFriend Obrey (Los Alamos, New Mexico)
ABSTRACT Fluorescent composites of surfactant-wrapped single-walled carbon nanotubes (SWNTs) were prepared by exposing suspensions of surfactant-wrapped carbon nanotubes to tetramethylorthosilicate (TMOS) vapor. Sodium deoxycholate (DOC) and sodium dodecylsulphate (SDS) were the surfactants. No loss in emission intensity was observed when the suspension of DOC-wrapped SWNTs were exposed to the TMOS vapors, but about a 50% decrease in the emission signal was observed from the SDS-wrapped SWNTs nanotubes. The decrease in emission was minimal by buffering the SDS/SWNT suspension prior to forming the composite. Fluorescent xerogels were prepared by adding glycerol to the SWNT suspensions prior to TMOS vapor exposure, followed by drying the gels. Fluorescent aerogels were prepared by replacing water in the gels with methanol and then exposing them to supercritical fluid drying conditions. The aerogels can be used for gas sensing.
FILED Wednesday, September 22, 2010
APPL NO 12/888260
ART UNIT 2884 — Optics
CURRENT CPC
Radiant energy
250/340
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US 08396649 Huang
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Jian Huang (Richmond, Canada)
ASSIGNEE(S) Westport Power Inc. (Vancouver, British Columbia, Canada)
INVENTOR(S) Jian Huang (Richmond, Canada)
ABSTRACT A method comprises steps for reconstructing in-cylinder pressure data from a vibration signal collected from a vibration sensor mounted on an engine component where it can generate a signal with a high signal-to-noise ratio, and correcting the vibration signal for errors introduced by vibration signal charge decay and sensor sensitivity. The correction factors are determined as a function of estimated motoring pressure and the measured vibration signal itself with each of these being associated with the same engine cycle. Accordingly, the method corrects for charge decay and changes in sensor sensitivity responsive to different engine conditions to allow greater accuracy in the reconstructed in-cylinder pressure data. An apparatus is also disclosed for practicing the disclosed method, comprising a vibration sensor, a data acquisition unit for receiving the vibration signal, a computer processing unit for processing the acquired signal and a controller for controlling the engine operation based on the reconstructed in-cylinder pressure.
FILED Friday, January 27, 2012
APPL NO 13/360519
ART UNIT 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems
CURRENT CPC
Data processing: Vehicles, navigation, and relative location
71/111
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08397052 Eichenberger et al.
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Alexandre E. Eichenberger (Chappaqua, New York);  Alan Gara (Mount Kisco, New York);  Kathryn M. O'Brien (South Salem, New York);  Martin Ohmacht (Yorktown Heights, New York);  Xiaotong Zhuang (Yorktown Heights, New York)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Alexandre E. Eichenberger (Chappaqua, New York);  Alan Gara (Mount Kisco, New York);  Kathryn M. O'Brien (South Salem, New York);  Martin Ohmacht (Yorktown Heights, New York);  Xiaotong Zhuang (Yorktown Heights, New York)
ABSTRACT Mechanisms are provided for controlling version pressure on a speculative versioning cache. Raw version pressure data is collected based on one or more threads accessing cache lines of the speculative versioning cache. One or more statistical measures of version pressure are generated based on the collected raw version pressure data. A determination is made as to whether one or more modifications to an operation of a data processing system are to be performed based on the one or more statistical measures of version pressure, the one or more modifications affecting version pressure exerted on the speculative versioning cache. An operation of the data processing system is modified based on the one or more determined modifications, in response to a determination that one or more modifications to the operation of the data processing system are to be performed, to affect the version pressure exerted on the speculative versioning cache.
FILED Wednesday, August 19, 2009
APPL NO 12/543688
ART UNIT 2111 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Electrical computers and digital processing systems: Processing architectures and instruction processing
712/214
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US 08397187 Sawada
FUNDED BY
Department of Energy (DOE)
APPLICANT(S) Jun Sawada (Austin, Texas)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) Jun Sawada (Austin, Texas)
ABSTRACT A verification tool receives a finite precision definition for an approximation of an infinite precision numerical function implemented in a processor in the form of a polynomial of bounded functions. The verification tool receives a domain for verifying outputs of segments associated with the infinite precision numerical function. The verification tool splits the domain into at least two segments, wherein each segment is non-overlapping with any other segment and converts, for each segment, a polynomial of bounded functions for the segment to a simplified formula comprising a polynomial, an inequality, and a constant for a selected segment. The verification tool calculates upper bounds of the polynomial for the at least two segments, beginning with the selected segment and reports the segments that violate a bounding condition.
FILED Friday, April 23, 2010
APPL NO 12/766163
ART UNIT 2825 — Semiconductors/Memory
CURRENT CPC
Computer-aided design and analysis of circuits and semiconductor masks
716/106
VIEW PATENT @ USPTO:  Full Text   PDF 

National Aeronautics and Space Administration (NASA) 

US 08393206 Chen
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Ping-Chih Chen (Scottsdale, Arizona)
ASSIGNEE(S)
INVENTOR(S) Ping-Chih Chen (Scottsdale, Arizona)
ABSTRACT This invention is a ground flutter testing system without a wind tunnel, called Dry Wind Tunnel (DWT) System. The DWT system consists of a Ground Vibration Test (GVT) hardware system, a multiple input multiple output (MIMO) force controller software, and a real-time unsteady aerodynamic force generation software, that is developed from an aerodynamic reduced order model (ROM). The ground flutter test using the DWT System operates on a real structural model, therefore no scaled-down structural model, which is required by the conventional wind tunnel flutter test, is involved. Furthermore, the impact of the structural nonlinearities on the aeroelastic stability can be included automatically. Moreover, the aeroservoelastic characteristics of the aircraft can be easily measured by simply including the flight control system in-the-loop. In addition, the unsteady aerodynamics generated computationally is interference-free from the wind tunnel walls. Finally, the DWT System can be conveniently and inexpensively carried out as a post GVT test with the same hardware, only with some possible rearrangement of the shakers and the inclusion of additional sensors.
FILED Tuesday, February 09, 2010
APPL NO 12/702510
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/147
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08393520 Ding
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) R. Jeffrey Ding (Athens, Alabama)
ASSIGNEE(S) The United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) R. Jeffrey Ding (Athens, Alabama)
ABSTRACT An ultrasonic stir welding system includes a welding head assembly having a plate and a rod passing through the plate. The rod is rotatable about a longitudinal axis thereof. During a welding operation, ultrasonic pulses are applied to the rod as it rotates about its longitudinal axis. The ultrasonic pulses are applied in such a way that they propagate parallel to the longitudinal axis of the rod.
FILED Thursday, September 22, 2011
APPL NO 13/240075
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Metal fusion bonding
228/112.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08393523 Ding
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) R. Jeffrey Ding (Athens, Alabama)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) R. Jeffrey Ding (Athens, Alabama)
ABSTRACT A method of performing ultrasonic stir welding uses a welding head assembly to include a plate and a rod passing through the plate. The rod is rotatable about a longitudinal axis thereof. In the method, the rod is rotated about its longitudinal axis during a welding operation. During the welding operation, a series of on-off ultrasonic pulses are applied to the rod such that they propagate parallel to the rod's longitudinal axis. At least a pulse rate associated with the on-off ultrasonic pulses is controlled.
FILED Thursday, June 14, 2012
APPL NO 13/523310
ART UNIT 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Metal fusion bonding
228/112.100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08393786 Sadleir
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) John E. Sadleir (Washington, District of Columbia)
ASSIGNEE(S) The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) John E. Sadleir (Washington, District of Columbia)
ABSTRACT Methods for forming sensors using transition edge sensors (TES) and sensors therefrom are described. The method includes forming a plurality of sensor arrays includes at least one TES device. The TES device includes a TES device body, a first superconducting lead contacting a first portion of the TES device body, and a second superconducting lead contacting of a second portion of the TES device body, where the first and second superconducting leads separated on the TES device body by a lead spacing. The lead spacing can be selected to be different for at least two of the plurality of sensor arrays. The method also includes determining a transition temperature for each of the plurality of sensor arrays and generating a signal responsive to detecting a change in the electrical characteristics of one of the plurality of sensor arrays meeting a transition temperature criterion.
FILED Friday, May 28, 2010
APPL NO 12/789954
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Thermal measuring and testing
374/100
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394492 Leventis et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Nicholas Leventis (Westlake, Ohio);  James C. Johnston (Euclid, Ohio);  Maria A. Kuczmarski (Independence, Ohio);  Mary Ann B. Meador (Strongsville, Ohio)
ASSIGNEE(S) The United States of America as represented by the United States National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) Nicholas Leventis (Westlake, Ohio);  James C. Johnston (Euclid, Ohio);  Maria A. Kuczmarski (Independence, Ohio);  Mary Ann B. Meador (Strongsville, Ohio)
ABSTRACT This invention comprises reinforced aerogel monoliths such as silica aerogels having a polymer coating on its outer geometric surface boundary, and to the method of preparing said aerogel monoliths. The polymer coatings on the aerogel monoliths are derived from polymer precursors selected from the group consisting of isocyanates as a precursor, precursors of epoxies, and precursors of polyimides. The coated aerogel monoliths can be modified further by encapsulating the aerogel with the polymer precursor reinforced with fibers such as carbon or glass fibers to obtain mechanically reinforced composite encapsulated aerogel monoliths.
FILED Thursday, October 28, 2004
APPL NO 10/974991
ART UNIT 1783 — Miscellaneous Articles, Stock Material
CURRENT CPC
Stock material or miscellaneous articles
428/319.300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394552 Gummalla et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Glenn Research Center (GLENN)
APPLICANT(S) Mallika Gummalla (Long Meadow, Massachusetts);  Jean Yamanis (South Glastonbury, Connecticut);  Benoit Olsommer (South Glastonbury, Connecticut);  Zissis Dardas (Worcester, Massachusetts);  Robert Bayt (League City, Texas);  Hari Srinivasan (Avon, Connecticut);  Arindam Dasgupta (West Hartford, Connecticut);  Larry Hardin (East Hartford, Connecticut)
ASSIGNEE(S) Hamilton Sundstrand Corporation (Windsor Locks, Connecticut)
INVENTOR(S) Mallika Gummalla (Long Meadow, Massachusetts);  Jean Yamanis (South Glastonbury, Connecticut);  Benoit Olsommer (South Glastonbury, Connecticut);  Zissis Dardas (Worcester, Massachusetts);  Robert Bayt (League City, Texas);  Hari Srinivasan (Avon, Connecticut);  Arindam Dasgupta (West Hartford, Connecticut);  Larry Hardin (East Hartford, Connecticut)
ABSTRACT A power system for an aircraft includes a solid oxide fuel cell system which generates electric power for the aircraft and an exhaust stream; and a heat exchanger for transferring heat from the exhaust stream of the solid oxide fuel cell to a heat requiring system or component of the aircraft. The heat can be transferred to fuel for the primary engine of the aircraft. Further, the same fuel can be used to power both the primary engine and the SOFC. A heat exchanger is positioned to cool reformate before feeding to the fuel cell. SOFC exhaust is treated and used as inerting gas. Finally, oxidant to the SOFC can be obtained from the aircraft cabin, or exterior, or both.
FILED Tuesday, September 19, 2006
APPL NO 11/524348
ART UNIT 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions
CURRENT CPC
Chemistry: Electrical current producing apparatus, product, and process
429/488
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394761 Marchionni et al.
FUNDED BY
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Mark Marchionni (Arlington, Massachusetts);  Ralph Kelly (Chestnut Hill, Massachusetts);  Beverly Lorell (Needham, Massachusetts);  Douglas B. Sawyer (Brookline, Massachusetts)
ASSIGNEE(S) Beth Israel Deaconess Medical Center (Boston, Massachusetts);  The Brigham and Women's Hospital, Inc. (Boston, Massachusetts);  Acorda Therapeutics, Inc. (Ardsley, New York)
INVENTOR(S) Mark Marchionni (Arlington, Massachusetts);  Ralph Kelly (Chestnut Hill, Massachusetts);  Beverly Lorell (Needham, Massachusetts);  Douglas B. Sawyer (Brookline, Massachusetts)
ABSTRACT The invention features methods of treating or preventing congestive heart failure by administering a polypeptide containing an epidermal growth factor-like domain encoded by a neuregulin gene.
FILED Wednesday, November 09, 2011
APPL NO 13/292193
ART UNIT 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08395093 Auffinger, III et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Materiel Command (AFMC)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Armaments Center (CCDC AC)
National Aeronautics and Space Administration (NASA)
Marshall Space Flight Center (MSFC)
APPLICANT(S) Frank Auffinger, III (Hamilton, Ohio);  Michael Richard Maddux (Jamestown, Ohio);  Kristopher Karl Aber (Cincinnati, Ohio);  Brandon Charles Kirby (Morgantown, West Virginia)
ASSIGNEE(S) Cornerstone Research Group, Inc. (Dayton, Ohio)
INVENTOR(S) Frank Auffinger, III (Hamilton, Ohio);  Michael Richard Maddux (Jamestown, Ohio);  Kristopher Karl Aber (Cincinnati, Ohio);  Brandon Charles Kirby (Morgantown, West Virginia)
ABSTRACT The preferred embodiment utilizes metal coated high strain fabric reinforcement including but not limited to fiberglass, cotton fiber, or other materials that can undergo deformation, and various resin or elastomer compounds to create a conductive polymer whose resistivity and resistance remain essentially constant under a strain of approximately 0-150% or more. Additionally, the preferred embodiment utilizes a method of imprinting, depositing, etching, or embossing a design or pattern of conductive metal on fabric used in composites. The use of designs of conductive metals wrapped around a deformable core and the unique features of elastomeric polymers allows for their use as a flexible circuit board, formable heaters, and other various uses.
FILED Tuesday, April 06, 2010
APPL NO 12/754708
ART UNIT 2897 — Semiconductors/Memory
CURRENT CPC
Electric heating
219/543
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08395150 Marks et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
Division of Materials Research (DMR)
APPLICANT(S) Tobin J. Marks (Evanston, Illinois);  Antonio Facchetti (Chicago, Illinois);  Lian Wang (Evanston, Illinois);  Myung-Han Yoon (Cambridge, Massachusetts);  Yu Yang (Santa Clara, California)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Tobin J. Marks (Evanston, Illinois);  Antonio Facchetti (Chicago, Illinois);  Lian Wang (Evanston, Illinois);  Myung-Han Yoon (Cambridge, Massachusetts);  Yu Yang (Santa Clara, California)
ABSTRACT Inorganic semiconducting compounds, composites and compositions thereof, and related device structures.
FILED Monday, January 16, 2012
APPL NO 13/351050
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/43
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US 08395243 Hoenk
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Michael E. Hoenk (Valencia, California)
ASSIGNEE(S) California Institute of Technology (Pasadenca, California)
INVENTOR(S) Michael E. Hoenk (Valencia, California)
ABSTRACT A semiconductor device has a multilayer doping to provide improved passivation by quantum exclusion. The multilayer doping includes a plurality M of doped layers, where M is an integer greater than 1. The dopant sheet densities in the M doped layers need not be the same, but in principle can be selected to be the same sheet densities or to be different sheet densities. M−1 interleaved layers provided between the M doped layers are not deliberately doped (also referred to as “undoped layers”). Structures with M=2, M=3 and M=4 have been demonstrated and exhibit improved passivation.
FILED Wednesday, June 15, 2011
APPL NO 13/160534
ART UNIT 2892 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/629
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US 08395568 Ray et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) William Johnstone Ray (Fountain Hills, Arizona);  Mark D. Lowenthal (Gilbert, Arizona);  Neil O. Shotton (Perry, Florida);  Richard A. Blanchard (Los Altos, California);  Mark Allan Lewandowski (Tempe, Arizona);  Kirk A. Fuller (Madison, Alabama);  Donald Odell Frazier (Huntsville, Alabama)
ASSIGNEE(S) NthDegree Technologies Worldwide Inc (Tempe, Arizona);  The United States of America as represented by the United States National Aeronautics and Space Administration (Washington, District of Columbia)
INVENTOR(S) William Johnstone Ray (Fountain Hills, Arizona);  Mark D. Lowenthal (Gilbert, Arizona);  Neil O. Shotton (Perry, Florida);  Richard A. Blanchard (Los Altos, California);  Mark Allan Lewandowski (Tempe, Arizona);  Kirk A. Fuller (Madison, Alabama);  Donald Odell Frazier (Huntsville, Alabama)
ABSTRACT The present invention provides an electronic apparatus, such as a lighting device comprised of light emitting diodes (LEDs) or a power generating apparatus comprising photovoltaic diodes, which may be created through a printing process, using a semiconductor or other substrate particle ink or suspension and using a lens particle ink or suspension. An exemplary apparatus comprises a base; at least one first conductor; a plurality of substantially spherical or optically resonant diodes coupled to the at least one first conductor; at least one second conductor coupled to the plurality of diodes; and a plurality of substantially spherical lenses suspended in a polymer attached or deposited over the diodes. The lenses and the suspending polymer have different indices of refraction. In some embodiments, the lenses and diodes have a ratio of mean diameters or lengths between about 10:1 and 2:1. The diodes may be LEDs or photovoltaic diodes, and in some embodiments, have a junction formed at least partially as a hemispherical shell or cap.
FILED Tuesday, September 15, 2009
APPL NO 12/560334
ART UNIT 2695 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC
Computer graphics processing and selective visual display systems
345/82
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US 08395770 Hug et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) William F. Hug (Altadena, California);  Ray D. Reid (Glendora, California);  Rohit Bhartia (Pasadena, California)
ASSIGNEE(S) Photon Systems (Covina, California)
INVENTOR(S) William F. Hug (Altadena, California);  Ray D. Reid (Glendora, California);  Rohit Bhartia (Pasadena, California)
ABSTRACT Spectroscopic chemical analysis methods and apparatus are disclosed which employ deep ultraviolet (e.g. in the 200 nm to 300 nm spectral range) electron beam pumped wide bandgap semiconductor lasers, incoherent wide bandgap semiconductor light emitting devices, and hollow cathode metal ion lasers to perform non-contact, non-invasive detection of unknown chemical analytes. These deep ultraviolet sources enable dramatic size, weight and power consumption reductions of chemical analysis instruments. Chemical analysis instruments employed in some embodiments include capillary and gel plane electrophoresis, capillary electrochromatography, high performance liquid chromatography, flow cytometry, flow cells for liquids and aerosols, and surface detection instruments. In some embodiments, Raman spectroscopic detection methods and apparatus use ultra-narrow-band angle tuning filters, acousto-optic tuning filters, and temperature tuned filters to enable ultra-miniature analyzers for chemical identification. In some embodiments Raman analysis is conducted along with photoluminescence spectroscopy (i.e. fluorescence and/or phosphorescence spectroscopy) to provide high levels of sensitivity and specificity in the same instrument.
FILED Friday, August 21, 2009
APPL NO 12/545772
ART UNIT 2877 — Optics
CURRENT CPC
Optics: Measuring and testing
356/317
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US 08395901 Tour et al.
FUNDED BY
Department of Defense (DOD)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
National Aeronautics and Space Administration (NASA)
APPLICANT(S) James M. Tour (Bellaire, Texas);  Yubao Li (Milpitas, California);  Alexander Sinitskiy (Ryazan, Russian Federation);  Lin Zhong (Houston, Texas);  Mian Dong (Houston, Texas);  Jun Yao (Houston, Texas)
ASSIGNEE(S) William Marsh Rice University (Houston, Texas)
INVENTOR(S) James M. Tour (Bellaire, Texas);  Yubao Li (Milpitas, California);  Alexander Sinitskiy (Ryazan, Russian Federation);  Lin Zhong (Houston, Texas);  Mian Dong (Houston, Texas);  Jun Yao (Houston, Texas)
ABSTRACT Vertically-stacked electronic devices having conductive carbon films are disclosed. The vertically-stacked devices exhibit non-linear current-versus-voltage response over a voltage sweep range in various embodiments. The vertically-stacked devices may be assembled into arrays where the vertically-stacked devices may be electrically addressed independently of one another. Uses of the vertically-stacked electronic devices and arrays as two-terminal memory devices, logic units, and sensors are disclosed. Crossbar arrays of vertically-stacked electronic devices having conductive carbon films and nanowire electrodes are disclosed.
FILED Thursday, November 13, 2008
APPL NO 12/270246
ART UNIT 2835 — Electrical Circuits and Systems
CURRENT CPC
Electricity: Electrical systems and devices
361/735
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US 08396729 Shearer et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
National Airspace System (NAS)
APPLICANT(S) Scott C. Shearer (Merritt Island, Florida);  John Nicholas Proferes (Cocoa Beach, Florida);  Mitchell D. Baker, Sr. (Titusville, Florida);  Kenneth B. Reilly (Palm Bay, Florida);  Vijai K. Tiwari (Orlando, Florida)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Scott C. Shearer (Merritt Island, Florida);  John Nicholas Proferes (Cocoa Beach, Florida);  Mitchell D. Baker, Sr. (Titusville, Florida);  Kenneth B. Reilly (Palm Bay, Florida);  Vijai K. Tiwari (Orlando, Florida)
ABSTRACT Systems, computer program products, and methods are disclosed for tracking an improvement event. An embodiment includes an event interface configured to receive a plurality of entries related to each of a plurality of improvement events. The plurality of entries includes a project identifier for the improvement event, a creation date, an objective, an action related to reaching the objective, and a first deadline related to the improvement event. A database interface is configured to store the plurality of entries in an event database.
FILED Wednesday, October 22, 2008
APPL NO 12/256248
ART UNIT 3684 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/7.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08397062 Roy-Chowdhury et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
APPLICANT(S) Ayan Roy-Chowdhury (Silver Spring, Maryland);  John S. Baras (Potomac, Maryland)
ASSIGNEE(S) University of Maryland, College Park (College Park, Maryland)
INVENTOR(S) Ayan Roy-Chowdhury (Silver Spring, Maryland);  John S. Baras (Potomac, Maryland)
ABSTRACT A method and system for authentication is provided. A central node for issuing certificates to a plurality of nodes associated with the central node in a network is also provided. The central node receives a first key from at least one node from among the plurality of nodes and generates a second key based on the received first key and generates a certificate for the at least one node. The generated certificate is transmitted to the at least one node.
FILED Wednesday, April 21, 2010
APPL NO 12/764266
ART UNIT 2439 — Cryptography and Security
CURRENT CPC
Electrical computers and digital processing systems: Support
713/157
VIEW PATENT @ USPTO:  Full Text   PDF 

National Science Foundation (NSF) 

US 08393281 Chen et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Engineering (ENG)
Division of Chemical and Transport Systems (CTS)
APPLICANT(S) Wei-Yin Chen (Oxford, Mississippi);  George Gowan (Taylor, Mississippi)
ASSIGNEE(S) University of Mississippi (University, Mississippi)
INVENTOR(S) Wei-Yin Chen (Oxford, Mississippi);  George Gowan (Taylor, Mississippi)
ABSTRACT A particle feeder is provided for feeding small particles at a uniform low feed rate. In some embodiments, the particle feeder includes a primary reservoir, a secondary reservoir, and a valve. The primary reservoir encloses an internal volume for holding particles and defining a hole through a bottom surface thereof. The valve includes a rod enclosed within and extending through the volume defined by the primary reservoir. The rod is movable between an open position, wherein particles can flow through the hole, and a closed position, wherein the rod blocks the hole. The actuator controls the movement of the rod between the open position and the closed position. The secondary reservoir has an internal volume, and a conduit for connecting the internal volume of the secondary reservoir with the internal volume of primary reservoir, such that particles can flow from the secondary reservoir into the primary reservoir.
FILED Friday, February 27, 2009
APPL NO 12/395285
ART UNIT 3743 — Printing/Measuring and Testing
CURRENT CPC
Furnaces
110/108
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US 08394640 Golovchenko et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Office of Scientific Research (AFOSR)
Air Force Research Laboratory (AFRL)
Department of Energy (DOE)
National Science Foundation (NSF)
APPLICANT(S) Jene A. Golovchenko (Lexington, Massachusetts);  Jiali Li (Fayetteville, Arkansas);  Derek Stein (Delft, Netherlands);  Marc H. Gershow (Cambridge, Massachusetts)
ASSIGNEE(S) President and Fellows of Harvard College (Cambridge, Massachusetts)
INVENTOR(S) Jene A. Golovchenko (Lexington, Massachusetts);  Jiali Li (Fayetteville, Arkansas);  Derek Stein (Delft, Netherlands);  Marc H. Gershow (Cambridge, Massachusetts)
ABSTRACT The invention features methods for evaluating the conformation of a polymer, for example, for determining the conformational distribution of a plurality of polymers and to detect binding or denaturation events. The methods employ a nanopore which the polymer, e.g., a nucleic acid, traverses. As the polymer traverses the nanopore, measurements of transport properties of the nanopore yield data on the conformation of the polymer.
FILED Monday, December 06, 2010
APPL NO 12/961021
ART UNIT 1774 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/86
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394679 Eaton et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Mark F Eaton (Austin, Texas);  Curtis Nathan Potter (Austin, Texas);  Andrew Miner (San Francisco, California)
ASSIGNEE(S) Stellarray, Inc. (Austin, Texas)
INVENTOR(S) Mark F Eaton (Austin, Texas);  Curtis Nathan Potter (Austin, Texas);  Andrew Miner (San Francisco, California)
ABSTRACT A structure and method for cold weld compression bonding using a metallic nano-structured gasket is provided. This structure and method allows a hermetic package to be formed at lower pressures and temperatures than are possible using bulk or conventional thin-film gasket materials.
FILED Wednesday, September 01, 2010
APPL NO 12/874212
ART UNIT 2823 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/118
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394708 Grier et al.
FUNDED BY
Department of Energy (DOE)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) David G. Grier (New York, New York);  Yael Roichman (New York, New York);  Weining Man (Princeton, New Jersey);  Paul Michael Chaikin (Pennington, New Jersey);  Paul Joseph Steinhardt (Princeton, New Jersey)
ASSIGNEE(S) New York University (New York, New York);  The Trustees of Princeton University (Princeton, New Jersey)
INVENTOR(S) David G. Grier (New York, New York);  Yael Roichman (New York, New York);  Weining Man (Princeton, New Jersey);  Paul Michael Chaikin (Pennington, New Jersey);  Paul Joseph Steinhardt (Princeton, New Jersey)
ABSTRACT A method and system for assembling a quasicrystalline heterostructure. A plurality of particles is provided with desirable predetermined character. The particles are suspended in a medium, and holographic optical traps are used to position the particles in a way to achieve an arrangement which provides a desired property.
FILED Friday, June 17, 2011
APPL NO 13/163460
ART UNIT 2812 — Semiconductors/Memory
CURRENT CPC
Semiconductor device manufacturing: Process
438/479
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394736 Flytzani-Stephanopoulos et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Maria Flytzani-Stephanopoulos (Winchester, Massachusetts);  Xiaoyan She (Richland, Washington)
ASSIGNEE(S) Tufts University (Medford, Massachusetts)
INVENTOR(S) Maria Flytzani-Stephanopoulos (Winchester, Massachusetts);  Xiaoyan She (Richland, Washington)
ABSTRACT A method includes contacting a catalyst including a metal having an average particle size of approximately one nanometer or greater with SO2; and reducing the average particle size of the metal.
FILED Tuesday, September 22, 2009
APPL NO 13/119507
ART UNIT 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography
CURRENT CPC
Catalyst, solid sorbent, or support therefor: Product or process of making
52/218
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US 08394934 Huang et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Biological Sciences (BIO)
Division of Molecular and Cellular Biosciences (MCB)
APPLICANT(S) Zhen Huang (Marietta, Georgia);  Jia Sheng (Atlanta, Georgia)
ASSIGNEE(S)
INVENTOR(S) Zhen Huang (Marietta, Georgia);  Jia Sheng (Atlanta, Georgia)
ABSTRACT A method is disclosed for synthesizing 2′,3′-didehydro-2′,3′-dideoxynucleosides (d4Ns) from a nucleophile-mediated elimination, such as a telluride-mediated elimination reaction. After substitution of 2,2′-anhydronucleosides with a nucleophile, such as a telluride monoanion, a telluride intermediate is formed, and its elimination leads to formation of the olefin products (d4Ns). This disclosure describes this telluride-assisted (or nucleophile-assisted) reaction and how to facilitate the substitution and elimination in order to form d4Ns.
FILED Friday, March 20, 2009
APPL NO 12/933619
ART UNIT 1623 — Organic Chemistry
CURRENT CPC
Organic compounds
536/1.110
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08395150 Marks et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Department of the Army (DOA)
Combat Capabilities Development Command (CCDC)
Army Research Laboratory (CCDC ARL)
Army Research Office (CCDC ARO)
National Aeronautics and Space Administration (NASA)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Chemistry (CHE)
Division of Materials Research (DMR)
APPLICANT(S) Tobin J. Marks (Evanston, Illinois);  Antonio Facchetti (Chicago, Illinois);  Lian Wang (Evanston, Illinois);  Myung-Han Yoon (Cambridge, Massachusetts);  Yu Yang (Santa Clara, California)
ASSIGNEE(S) Northwestern University (Evanston, Illinois)
INVENTOR(S) Tobin J. Marks (Evanston, Illinois);  Antonio Facchetti (Chicago, Illinois);  Lian Wang (Evanston, Illinois);  Myung-Han Yoon (Cambridge, Massachusetts);  Yu Yang (Santa Clara, California)
ABSTRACT Inorganic semiconducting compounds, composites and compositions thereof, and related device structures.
FILED Monday, January 16, 2012
APPL NO 13/351050
ART UNIT 2822 — Semiconductors/Memory
CURRENT CPC
Active solid-state devices
257/43
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08395282 Joannopoulos et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) John D. Joannopoulos (Belmont, Massachusetts);  Aristeidis Karalis (Cambridge, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) John D. Joannopoulos (Belmont, Massachusetts);  Aristeidis Karalis (Cambridge, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ABSTRACT The electromagnetic energy transfer device includes a first resonator structure receiving energy from an external power supply. The first resonator structure has a first Q-factor. A second resonator structure is positioned distal from the first resonator structure, and supplies useful working power to an external load. The second resonator structure has a second Q-factor. The distance between the two resonators can be larger than the characteristic size of each resonator. Non-radiative energy transfer between the first resonator structure and the second resonator structure is mediated through coupling of their resonant-field evanescent tails.
FILED Tuesday, March 31, 2009
APPL NO 12/415667
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Electrical transmission or interconnection systems
37/104
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US 08395283 Joannopoulos et al.
FUNDED BY
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) John D. Joannopoulos (Belmont, Massachusetts);  Aristeidis Karalis (Boston, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ASSIGNEE(S) Massachusetts Institute of Technology (Cambridge, Massachusetts)
INVENTOR(S) John D. Joannopoulos (Belmont, Massachusetts);  Aristeidis Karalis (Boston, Massachusetts);  Marin Soljacic (Belmont, Massachusetts)
ABSTRACT Described herein are embodiments of a source resonator optionally coupled to an energy source, and a second resonator, optionally coupled to an energy drain that may be located a distance from the source resonator. The source resonator and the second resonator may be coupled to provide κ/sqrt(Γ1Γ2)>0.2 via near-field wireless energy transfer among the source resonator and the second resonator over distances up to at least the characteristic size of a resonator.
FILED Wednesday, December 16, 2009
APPL NO 12/639961
ART UNIT 2836 — Electrical Circuits and Systems
CURRENT CPC
Electrical transmission or interconnection systems
37/104
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US 08395696 Ng et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Yi-Ren Ng (Mountain View, California);  Patrick M. Hanrahan (Portola Valley, California);  Marc A. Levoy (Stanford, California);  Mark A. Horowitz (Menlo Park, California)
ASSIGNEE(S) The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California)
INVENTOR(S) Yi-Ren Ng (Mountain View, California);  Patrick M. Hanrahan (Portola Valley, California);  Marc A. Levoy (Stanford, California);  Mark A. Horowitz (Menlo Park, California)
ABSTRACT Image data is processed to facilitate focusing and/or optical correction. According to an example embodiment of the present invention, an imaging arrangement collects light data corresponding to light passing through a particular focal plane. The light data is collected using an approach that facilitates the determination of the direction from which various portions of the light incident upon a portion of the focal plane emanate from. Using this directional information in connection with value of the light as detected by photosensors, an image represented by the light is selectively focused and/or corrected.
FILED Friday, April 01, 2011
APPL NO 13/078894
ART UNIT 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Television
348/349
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US 08396181 Naranjo et al.
FUNDED BY
Department of Defense (DOD)
Department of the Navy (DON)
National Science Foundation (NSF)
Directorate for Mathematical and Physical Sciences (MPS)
Division of Materials Research (DMR)
APPLICANT(S) Brian Naranjo (Fullerton, California);  James Gimzewski (Santa Monica, California);  Seth Putterman (Los Angeles, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Brian Naranjo (Fullerton, California);  James Gimzewski (Santa Monica, California);  Seth Putterman (Los Angeles, California)
ABSTRACT Gently heating a pyroelectric crystal in a deuterated atmosphere can generate fusion under desktop conditions. The electrostatic field of the crystal is used to generate and accelerate a deuteron beam (>100 keV and >4 nA), which, upon striking a deuterated target, produces a neutron flux over 400 times the background level. The presence of neutrons within the target is confirmed by pulse shape analysis and proton recoil spectroscopy. Several elements of the system may be modified, including the configuration of the crystal or crystals, the composition of the surrounding environment and the target, the use of multiple probe tips, and the composition of the probe tip.
FILED Tuesday, May 08, 2007
APPL NO 11/745556
ART UNIT 2894 — Semiconductors/Memory
CURRENT CPC
Induced nuclear reactions: Processes, systems, and elements
376/114
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US 08396315 Brajovic
FUNDED BY
National Science Foundation (NSF)
Directorate for Computer and Information Science and Engineering (CISE)
Division of Information and Intelligent Systems (IIS)
APPLICANT(S) Vladimir Brajovic (Pittsburgh, Pennsylvania)
ASSIGNEE(S)
INVENTOR(S) Vladimir Brajovic (Pittsburgh, Pennsylvania)
ABSTRACT A method for sensing an optical image and producing an improved image signal, includes the steps of: supplying a first signal to a first plurality of nodes, the nodes residing in an integrated circuit substrate; producing a second signal at a second plurality of nodes residing in the integrated circuit substrate, the first plurality of nodes substantially corresponding to the second plurality of nodes, wherein the step of producing the second signal includes: imposing a smoothness constraint on the second signal restricting a signal difference between the nodes of the second signal, the smoothness constraint imposed with a plurality of horizontal electronic element; imposing a closeness constraint on the second signal, thereby restricting a signal difference between the corresponding nodes in the first signal and the second signal, the closeness constraint imposed with a plurality of vertical electronic element; and balancing the smoothness constraint and the closeness constraint with a balancing means controlling the vertical electronic elements, the horizontal electronic elements, or both the vertical and the horizontal elements, the balancing means controlled by at least a portion of the first signal.
FILED Wednesday, December 22, 2010
APPL NO 12/976178
ART UNIT 2668 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/254
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US 08396884 Singh et al.
FUNDED BY
National Science Foundation (NSF)
APPLICANT(S) Ambuj Kumar Singh (Santa Barbara, California);  Huahai He (San Jose, California);  Sayan Ranu (Goleta, California)
ASSIGNEE(S) The Regents of the University of California (Oakland, California)
INVENTOR(S) Ambuj Kumar Singh (Santa Barbara, California);  Huahai He (San Jose, California);  Sayan Ranu (Goleta, California)
ABSTRACT A method for analyzing, querying, and mining graph databases using subgraph and similarity querying. An index structure, known as a closure tree, is defined for topological summarization of a set of graphs. In addition, a significance model is created in which the graphs are transformed into histograms of primitive components. Finally, connected substructures or clusters, comprising paths or trees, are detected in networks found in the graph databases using a random walk technique and a repeated random walk technique.
FILED Monday, March 28, 2011
APPL NO 13/073452
ART UNIT 2157 — Data Bases & File Management
CURRENT CPC
Data processing: Database and file management or data structures
77/760
VIEW PATENT @ USPTO:  Full Text   PDF 

National Security Agency (NSA) 

US 08395947 Harvard et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) Qawi I. Harvard (Santa Clara, California);  Robert J. Drost (Los Altos, California);  R. Jacob Baker (Boise, Idaho)
ASSIGNEE(S) Oracle America, Inc. (Redwood Shores, California)
INVENTOR(S) Qawi I. Harvard (Santa Clara, California);  Robert J. Drost (Los Altos, California);  R. Jacob Baker (Boise, Idaho)
ABSTRACT A memory device with increased communication bandwidth is described. In this memory device, control logic routes data signals from a memory array using inactive bitlines in response to a read command. These data signals are then placed on an adjacent unused input/output (I/O) line or routing channel, as opposed to a proximate I/O line that is in use. For example, unused bitlines located on the top and bottom of the memory array may be used to route data signals to adjacent local I/O lines. In particular, the data signals can be placed on unused local I/O lines which are associated with adjacent bitline sense amplifiers. The resulting increased communication bandwidth can overcome the constraints imposed by the limited number of local I/O lines in the memory device without appreciably increasing the chip size, power consumption, or cost.
FILED Friday, April 08, 2011
APPL NO 13/082785
ART UNIT 2824 — Semiconductors/Memory
CURRENT CPC
Static information storage and retrieval
365/189.150
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08396053 Giles et al.
FUNDED BY
Department of Defense (DOD)
National Security Agency (NSA)
APPLICANT(S) James Ryan Giles (Yorktown Heights, New York);  Rohit Wagle (Elmsford, New York);  Xiaolan J. Zhang (Champaign, Illinois)
ASSIGNEE(S) International Business Machines Corporation (Armonk, New York)
INVENTOR(S) James Ryan Giles (Yorktown Heights, New York);  Rohit Wagle (Elmsford, New York);  Xiaolan J. Zhang (Champaign, Illinois)
ABSTRACT An illustrative embodiment of the present invention includes a method for routing at least one packet from at least one source node to at least one destination node, each node is operatively coupled to a given packet switch within a plurality of packet switches operatively coupled to a given circuit switch. The method includes a step of establishing one or more Virtual Local Area Networks (VLANs). Each VLAN comprising a subset of the plurality of packet switches operatively coupled to the given circuit switch. At least one of the one or more VLANs comprises the at least one packet switch to which the source and destination nodes are operatively coupled. The method also includes a step of routing the at least one packet from the source node to the destination node over at least one loop-free path comprised of one or more packet switches within a given VLAN.
FILED Thursday, April 24, 2008
APPL NO 12/108861
ART UNIT 2477 — Multiplex and VoIP
CURRENT CPC
Multiplex communications
370/352
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08396912 Sinutko
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) Michael Sinutko (Glen Burnie, Maryland)
ASSIGNEE(S) The United States Government as Represented by the Director, National Security Agency (Washington, District of Columbia)
INVENTOR(S) Michael Sinutko (Glen Burnie, Maryland)
ABSTRACT The IIR resonator digital filter which is the subject of this patent invention comprises a first register having a plurality of inputs and outputs, a multiplexer/demultiplexer having a plurality of inputs and outputs, a first multiplier having a plurality of inputs and an output, a second multiplier having a plurality of inputs and an output, a third multiplier having a plurality of inputs and an output, an adder having a plurality of inputs and an output, a subtractor having a plurality of inputs and an output, and a second register having an input and a plurality of outputs. The IIR resonator digital filter features a multiplexer/demultiplexer that has five logical states.
FILED Thursday, August 05, 2010
APPL NO 12/806256
ART UNIT 2193 — Interprocess Communication and Software Development
CURRENT CPC
Electrical computers: Arithmetic processing and calculating
78/300
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08397146 York
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) Eric V. York (Severn, Maryland)
ASSIGNEE(S) The United States of America as Represented by the Director of the National Security Agency (Washington, District of Columbia)
INVENTOR(S) Eric V. York (Severn, Maryland)
ABSTRACT A device and method of determining candidates to decode by receiving a message, selecting m, identifying m voltages in message near zero volts, generating binary version of message, generating candidates that are variations of the binary message by varying the m positions, multiplying a modified binary message by the parity check matrix of the message, generating a matrix of the rows of the parity check matrix corresponding to the m positions, determining a rank v of the matrix, eliminating rows that are not linearly independent, determining if the sixth step result is in a span of the ninth step result, if so then there are 2m-1-2m-v(m−1) candidates, where the candidates can multiply the seventh step result to get the sixth step result and candidates with odd weights more than one Hamming distance from the candidates, otherwise there are 2m-1 candidates having odd weight.
FILED Friday, March 25, 2011
APPL NO 13/066852
ART UNIT 2112 — Computer Error Control, Reliability, & Control Systems
CURRENT CPC
Error detection/correction and fault detection/recovery
714/794
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08397284 Kommareddy et al.
FUNDED BY
National Security Agency (NSA)
APPLICANT(S) Chris Kommareddy (Seattle, Washington);  Samrat Bhattacharjee (Silver Spring, Maryland);  Mark A. Shayman (Potomac, Maryland);  Richard La (Gaithersburg, Maryland)
ASSIGNEE(S) University of Maryland (College Park, Maryland)
INVENTOR(S) Chris Kommareddy (Seattle, Washington);  Samrat Bhattacharjee (Silver Spring, Maryland);  Mark A. Shayman (Potomac, Maryland);  Richard La (Gaithersburg, Maryland)
ABSTRACT A denial-of-service network attack detection system is deployable in single-homed and multi-homed stub networks. The detection system maintains state information of flows entering and leaving the stub domain to determine if exiting traffic exceeds traffic entering the system. Monitors perform simple processing tasks on sampled packets at individual routers in the network at line speed and perform more intensive processing at the routers periodically. The monitors at the routers form an overlay network and communicate pertinent traffic state information between nodes. The state information is collected and analyzed to determine the presence of an attack.
FILED Wednesday, January 17, 2007
APPL NO 11/624101
ART UNIT 2435 — Cryptography and Security
CURRENT CPC
Information security
726/13
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Transportation (USDOT) 

US 08395521 Kauffman et al.
FUNDED BY
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
APPLICANT(S) Robert E. Kauffman (Centerville, Ohio);  J. Douglas Wolf (Kettering, Ohio)
ASSIGNEE(S) University of Dayton (Dayton, Ohio)
INVENTOR(S) Robert E. Kauffman (Centerville, Ohio);  J. Douglas Wolf (Kettering, Ohio)
ABSTRACT Smart aerospace structures are described herein utilizing a deactivated RFID tag including an IC and an electrical by-pass. The electrical by-pass is conductive and the electrical by-pass is in parallel with the IC such that the deactivated RFID becomes activated upon an abnormal condition, such as an improper clamp installation, a clamp failure, an impact, a thermal event or a crack.
FILED Friday, February 05, 2010
APPL NO 12/701056
ART UNIT 2689 — Signal Processing and Control Processing in Disk Drives
CURRENT CPC
Communications: Electrical
340/665
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08396729 Shearer et al.
FUNDED BY
National Aeronautics and Space Administration (NASA)
Department of Transportation (USDOT)
Federal Aviation Administration (FAA)
National Airspace System (NAS)
APPLICANT(S) Scott C. Shearer (Merritt Island, Florida);  John Nicholas Proferes (Cocoa Beach, Florida);  Mitchell D. Baker, Sr. (Titusville, Florida);  Kenneth B. Reilly (Palm Bay, Florida);  Vijai K. Tiwari (Orlando, Florida)
ASSIGNEE(S) The Boeing Company (Chicago, Illinois)
INVENTOR(S) Scott C. Shearer (Merritt Island, Florida);  John Nicholas Proferes (Cocoa Beach, Florida);  Mitchell D. Baker, Sr. (Titusville, Florida);  Kenneth B. Reilly (Palm Bay, Florida);  Vijai K. Tiwari (Orlando, Florida)
ABSTRACT Systems, computer program products, and methods are disclosed for tracking an improvement event. An embodiment includes an event interface configured to receive a plurality of entries related to each of a plurality of improvement events. The plurality of entries includes a project identifier for the improvement event, a creation date, an objective, an action related to reaching the objective, and a first deadline related to the improvement event. A database interface is configured to store the plurality of entries in an event database.
FILED Wednesday, October 22, 2008
APPL NO 12/256248
ART UNIT 3684 — Business Methods - Incentive Programs, Coupons; Electronic Shopping; Business Cryptography, Voting; Health Care; Point of Sale, Inventory, Accounting; Business Processing, Electronic Negotiation
CURRENT CPC
Data processing: Financial, business practice, management, or cost/price determination
75/7.110
VIEW PATENT @ USPTO:  Full Text   PDF 

Small Business Administration (SBA) 

US 08393206 Chen
FUNDED BY
National Aeronautics and Space Administration (NASA)
NASA Shared Services Center (NSSC)
Small Business Administration (SBA)
Small Business Technology Transfer (STTR)
APPLICANT(S) Ping-Chih Chen (Scottsdale, Arizona)
ASSIGNEE(S)
INVENTOR(S) Ping-Chih Chen (Scottsdale, Arizona)
ABSTRACT This invention is a ground flutter testing system without a wind tunnel, called Dry Wind Tunnel (DWT) System. The DWT system consists of a Ground Vibration Test (GVT) hardware system, a multiple input multiple output (MIMO) force controller software, and a real-time unsteady aerodynamic force generation software, that is developed from an aerodynamic reduced order model (ROM). The ground flutter test using the DWT System operates on a real structural model, therefore no scaled-down structural model, which is required by the conventional wind tunnel flutter test, is involved. Furthermore, the impact of the structural nonlinearities on the aeroelastic stability can be included automatically. Moreover, the aeroservoelastic characteristics of the aircraft can be easily measured by simply including the flight control system in-the-loop. In addition, the unsteady aerodynamics generated computationally is interference-free from the wind tunnel walls. Finally, the DWT System can be conveniently and inexpensively carried out as a post GVT test with the same hardware, only with some possible rearrangement of the shakers and the inclusion of additional sensors.
FILED Tuesday, February 09, 2010
APPL NO 12/702510
ART UNIT 2856 — Printing/Measuring and Testing
CURRENT CPC
Measuring and testing
073/147
VIEW PATENT @ USPTO:  Full Text   PDF 
US 08394889 Bulluck et al.
FUNDED BY
Department of Defense (DOD)
Department of the Air Force (DAF)
Air Force Research Laboratory (AFRL)
Small Business Administration (SBA)
Small Business Innovation Research (SBIR)
APPLICANT(S) John W. Bulluck (Spicewood, Texas);  Brad A. Rix (Spicewood, Texas)
ASSIGNEE(S) Texas Research International Inc. (Austin, Texas)
INVENTOR(S) John W. Bulluck (Spicewood, Texas);  Brad A. Rix (Spicewood, Texas)
ABSTRACT A composition and process for manufacturing a camouflaged aircraft component. The process includes providing an aircraft component; applying an uncured coating onto the aircraft component wherein the uncured coating comprises polysilazane resin, at least one pigment, at least one matting agent, and at least one diluent; allowing the diluent to evaporate; curing the coating to provided a cured coating that comprises cured polysilazane, at least one pigment, and at least one matting agent.
FILED Tuesday, March 22, 2011
APPL NO 13/065449
ART UNIT 1765 — Organic Chemistry, Polymers, Compositions
CURRENT CPC
Synthetic resins or natural rubbers
524/588
VIEW PATENT @ USPTO:  Full Text   PDF 

Central Intelligence Agency (CIA) 

US 08394642 Jovanovich et al.
FUNDED BY
Central Intelligence Agency (CIA)
APPLICANT(S) Stevan B. Jovanovich (Livermore, California);  William D. Nielsen (San Jose, California);  David S. Cohen (San Bruno, California);  Michael Recknor (Oakland, California);  Mattias Vangbo (Fremont, California);  Ezra Van Gelder (Palo Alto, California);  Lars Majlof (San Jose, California);  Omar El-Sissi (Fremont, California)
ASSIGNEE(S) IntegenX Inc. (Pleasanton, California)
INVENTOR(S) Stevan B. Jovanovich (Livermore, California);  William D. Nielsen (San Jose, California);  David S. Cohen (San Bruno, California);  Michael Recknor (Oakland, California);  Mattias Vangbo (Fremont, California);  Ezra Van Gelder (Palo Alto, California);  Lars Majlof (San Jose, California);  Omar El-Sissi (Fremont, California)
ABSTRACT The invention provides a system that can process a raw biological sample, perform a biochemical reaction and provide an analysis readout. For example, the system can extract DNA from a swab, amplify STR loci from the DNA, and analyze the amplified loci and STR markers in the sample. The system integrates these functions by using microfluidic components to connect what can be macrofluidic functions. In one embodiment the system includes a sample purification module, a reaction module, a post-reaction clean-up module, a capillary electrophoresis module and a computer. In certain embodiments, the system includes a disposable cartridge for performing analyte capture. The cartridge can comprise a fluidic manifold having macrofluidic chambers mated with microfluidic chips that route the liquids between chambers. The system fits within an enclosure of no more than 10 ft3. and can be a closed, portable, and/or a battery operated system. The system can be used to go from raw sample to analysis in less than 4 hours.
FILED Monday, June 07, 2010
APPL NO 12/795515
ART UNIT 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus
CURRENT CPC
Chemistry: Analytical and immunological testing
436/94
VIEW PATENT @ USPTO:  Full Text   PDF 

Department of Veterans Affairs (DVA) 

US 08394763 Forte et al.
FUNDED BY
Department of Veterans Affairs (DVA)
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
APPLICANT(S) Michael Forte (Portland, Oregon);  Dennis Bourdette (Portland, Oregon);  Gail Marracci (Scappoose, Oregon)
ASSIGNEE(S) Oregon Health and Science University (Portland, Oregon);  The United States of America as represented by the Department of Veterans Affairs (Washington, District of Columbia)
INVENTOR(S) Michael Forte (Portland, Oregon);  Dennis Bourdette (Portland, Oregon);  Gail Marracci (Scappoose, Oregon)
ABSTRACT A method for treating a subject with multiple sclerosis is disclosed herein. In one embodiment, a method is provided for treating a subject with multiple sclerosis that includes administering to the subject a therapeutically effective amount of a cyclosporin compound.
FILED Friday, September 26, 2008
APPL NO 12/679778
ART UNIT 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes
CURRENT CPC
Drug, bio-affecting and body treating compositions
514/2.900
VIEW PATENT @ USPTO:  Full Text   PDF 

National Geospatial Intelligence Agency (NGA) 

US 08396293 Korah et al.
FUNDED BY
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
National Geospatial Intelligence Agency (NGA)
APPLICANT(S) Thommen Korah (Marina Del Rey, California);  Swarup S. Medasani (Thousand Oaks, California);  Yuri Owechko (Newbury Park, California)
ASSIGNEE(S) HRL Laboratories, LLC (Malibu, California)
INVENTOR(S) Thommen Korah (Marina Del Rey, California);  Swarup S. Medasani (Thousand Oaks, California);  Yuri Owechko (Newbury Park, California)
ABSTRACT A method of recognizing geometrically salient objects from sensed data points collected in a 3D environment includes using a sensor that collects a plurality of sensed data points each having spatial coordinate information in three dimensions x, y and z, populating a strip histogram grid having a plurality of strips, each strip having a z, dx and dy dimensions, wherein dx is a portion of an x dimension and dy is a portion of a y dimension of the strip histogram grid, by assigning each sensed data point to a strip that has x, y and z dimensions that encompass the spatial coordinate information of the respective assigned sensed data point, and segmenting the strip histogram grid into a plurality of segmented regions, each segmented region comprising one strip or a group of neighboring strips having similar attributes.
FILED Tuesday, December 22, 2009
APPL NO 12/644751
ART UNIT 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation
CURRENT CPC
Image analysis
382/171
VIEW PATENT @ USPTO:  Full Text   PDF 

Government Rights Acknowledged 

How To Use This Page 

THE FEDINVENT PATENT DETAILS PAGE

Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.

This week's information is published in the FedInvent Patents report for Tuesday, March 12, 2013.

The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.

HOW IS THE INFORMATION ORGANIZED?

Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.

WHAT INFORMATION WILL I FIND?

THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:

FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:

Department of Health and Human Services (HHS)
     National Institutes of Health (NIH)
         National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Department of Defense (DOD)
     Defense Advanced Research Projects Agency (DARPA)
         Army Research Office (ARO)

We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.

APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.

Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:

APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC

APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)

INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.

ABSTRACT
The abstract as it appears on the patent.

FILED
The date of the patent application including the day of the week.

APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.

ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:

3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices

You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.

CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.

The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.

The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.

  • A61B 1/149 (20130101)
  • A61B 1/71 (20130101)
  • A61B 1/105 (20130101)

The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.

VIEW PATENT
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You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.

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