FedInvent™ Patents
Patent Details for Tuesday, May 28, 2013
This page was updated on Monday, March 27, 2023 at 03:47 AM GMT
Department of Health and Human Services (HHS)
| US 08448456 | Larson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dale Larson (Waban, Massachusetts); Jeffrey Ruberti (Lexington, Massachusetts); John Slusarz (Brookline, Massachusetts); Nicholas Goulas (Tewksbury, Massachusetts); Erin Rush (Middletown, Connecticut); Trevor Ehret (Syracuse, New York) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Dale Larson (Waban, Massachusetts); Jeffrey Ruberti (Lexington, Massachusetts); John Slusarz (Brookline, Massachusetts); Nicholas Goulas (Tewksbury, Massachusetts); Erin Rush (Middletown, Connecticut); Trevor Ehret (Syracuse, New York) |
| ABSTRACT | A drilling system including a motor that produces a sonic, linear oscillatory motion is provided for removing a frozen biological sample from a stored frozen specimen and methods of use thereof without thawing the remainder of the specimen. The stator and slider assembly is operated by a servo controller which can communicate and be programmed through a port of a PC equipped with software. |
| FILED | Tuesday, January 16, 2007 |
| APPL NO | 12/087695 |
| ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Refrigeration 062/62 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449445 | Ludlow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christy Leslie Ludlow (Bethesda, Maryland); Newlin Morgan (Bethesda, Maryland); George Dold (Boyds, Maryland); Soren Lowell (Syracuse, New York) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Christy Leslie Ludlow (Bethesda, Maryland); Newlin Morgan (Bethesda, Maryland); George Dold (Boyds, Maryland); Soren Lowell (Syracuse, New York) |
| ABSTRACT | A device for volitional swallowing with a substitute sensory system comprises a band 101 wrapped around the neck with a vibrator 102 positioned over the larynx. Upon activation by a button 103 on a spoon 104 held by an operator, such as the subject 105, the vibrator 102 moves and vibrates the larynx. The patient 105 initiates the sensory stimulation immediately prior to the patient's own initiation of a swallow by viewing on a display screen 106 a movement feedback signal 107, possibly from a piezo-electric sensor 108 also contained in the band 101 which will also be displayed on the display screen 106. The signal 109 from the switch device initiating sensory stimulation will be presented on the same display screen 106 for the patient 105 and trainer to observe when the button or switch 103 is activated for sensory stimulation in relation to the onset of the swallow. |
| FILED | Monday, September 29, 2008 |
| APPL NO | 12/240398 |
| ART UNIT | 3735 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/23 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449623 | Boone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Alan Boone (Seattle, Washington); Ben Gilbert Macomber (Shoreline, Washington); Lonnie Love (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | Orthocare Innovations LLC (Oklahoma City, Oklahoma); UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | David Alan Boone (Seattle, Washington); Ben Gilbert Macomber (Shoreline, Washington); Lonnie Love (Oak Ridge, Tennessee) |
| ABSTRACT | A hydraulic device includes a first plate that pivots in a first direction, a second plate that pivots in a second direction orthogonal to the first direction, a first hydraulic system comprising a first cylinder and piston, a second cylinder and piston and, channels connecting the first cylinder to the second cylinder, the first hydraulic system filled with hydraulic fluid, wherein the transfer of fluid between the first cylinder and second cylinder pivots the first plate, and a second hydraulic system comprising a third cylinder and piston, a fourth cylinder and piston and, channels connecting the third cylinder to the fourth cylinder, the second hydraulic system filled with hydraulic fluid, wherein the transfer of fluid between the third cylinder and fourth cylinder pivots the second plate. |
| FILED | Monday, September 20, 2010 |
| APPL NO | 12/886380 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Prosthesis 623/26 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449842 | Knopp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kevin J. Knopp (Newburyport, Massachusetts); Daryoosh Vakhshoori (Cambridge, Massachusetts); Peidong Wang (Carlisle, Massachusetts); Masud Azimi (Belmont, Massachusetts); Scott E. Miller (Somerville, Massachusetts); Jason Goldstein (Salem, New Hampshire); Stephen McLaughlin (Andover, Massachusetts) |
| ASSIGNEE(S) | Thermo Scientific Portable Analytical Instruments Inc. (Tewksbury, Massachusetts) |
| INVENTOR(S) | Kevin J. Knopp (Newburyport, Massachusetts); Daryoosh Vakhshoori (Cambridge, Massachusetts); Peidong Wang (Carlisle, Massachusetts); Masud Azimi (Belmont, Massachusetts); Scott E. Miller (Somerville, Massachusetts); Jason Goldstein (Salem, New Hampshire); Stephen McLaughlin (Andover, Massachusetts) |
| ABSTRACT | Systems and methods disclosed include: a support apparatus configured to detachably receive a chip; movable pins extendible from a first position to a second position, where, in the first position, the movable pins do not contact a chip positioned on the support apparatus, and in the second position, the movable pins contact electrical terminals of a heating element within a chip positioned on the support apparatus; a radiation source configured to direct radiation to be incident on a chip positioned on the support apparatus; a detector; and an electronic processor, the electronic processor being configured to detect molecules in a sample positioned within the chip, and to determine a temperature of the chip by measuring an electrical resistance between two of the multiple pins connected to the electrical terminals. |
| FILED | Thursday, March 11, 2010 |
| APPL NO | 12/722211 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/536 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449864 | Piliponsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Adrian Martin Piliponsky (Mountain View, California); Mindy Tsai (Palo Alto, California); Stephen J. Galli (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Adrian Martin Piliponsky (Mountain View, California); Mindy Tsai (Palo Alto, California); Stephen J. Galli (Stanford, California) |
| ABSTRACT | Sepsis is a complex, incompletely understood and often fatal disorder, typically accompanied by hypotension, that is considered to represent a dysregulated host response to an infection. Neurotensin (NT) is 13-amino-acid peptide that, among its multiple effects, induces hypotension. It is shown herein that plasma concentrations of NT are increased in humans with sepsis and in mice after caecal ligation and puncture (CLP), a model of sepsis. Mast cells can degrade NT through neurotensin receptor 1-and neurolysin-dependent mechanisms, diminishing the hypotensive effects of NT, reducing intraperitoneal NT concentrations, and improving survival. These findings show that mast cells can regulate NT concentrations, and identify NT as a biomarker and therapeutic target in sepsis. |
| FILED | Friday, October 19, 2007 |
| APPL NO | 11/875710 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/145 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449875 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Irvin S.Y. Chen (Palos Verdes Estates, California); Kouki Morizono (Los Angeles, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Irvin S.Y. Chen (Palos Verdes Estates, California); Kouki Morizono (Los Angeles, California) |
| ABSTRACT | The present invention provides targeted lentiviral vectors that are psuedotyped with mutated Sindbis envelopes. For example, mutations in the Sindbis E2 protein are used to alter viral titer, specificity, specificity index, tropism, and susceptibility to host immune response. Typically, one or more of the E1, E2, or E3 proteins can be mutated at one or more amino acid positions. The psuedotyped, targeted lentiviral vectors of the invention are used to transduce heterologous genes into a cell and can be used for in vivo and ex vivo therapeutic applications, as well as for diagnostic and research tool applications. |
| FILED | Friday, November 20, 2009 |
| APPL NO | 12/623265 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449880 | Dolnik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vladislav Dolnik (Palo Alto, California); William A. Gurske (Fremont, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vladislav Dolnik (Palo Alto, California); William A. Gurske (Fremont, California) |
| ABSTRACT | Disclosed herein is a composition and method for sample preparation of proteins for their size separation by electrophoresis, suitable for molecular-weight determination of proteins in the range between about 14,000 and 500,000. In an embodiment, proteins, particularly those exhibiting biased migration, are modified to change their intrinsic charge, or carbohydrate component to improve accuracy of their molecular weights as determined by electrophoretic size separation via their interaction with ionic surfactants. In a preferred embodiment, the proteins are carbamylated with potassium cyanate and their carbohydrate components are oxidized with sodium periodate. |
| FILED | Monday, November 22, 2010 |
| APPL NO | 12/952166 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449888 | Zurawski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gerard Zurawski (Midlothian, Texas); Jacques F. Banchereau (Montclair, New Jersey); Eynav Klechevsky (Haifa, Israel); Sandra Zurawski (Midlothian, Texas); Anne-Laure Flamar (Dallas, Texas) |
| ASSIGNEE(S) | Baylor Research Institute (Dallas, Texas) |
| INVENTOR(S) | Gerard Zurawski (Midlothian, Texas); Jacques F. Banchereau (Montclair, New Jersey); Eynav Klechevsky (Haifa, Israel); Sandra Zurawski (Midlothian, Texas); Anne-Laure Flamar (Dallas, Texas) |
| ABSTRACT | The present invention includes compositions and methods for increasing the effectiveness of antigen presentation using a DCIR-specific antibody or fragment thereof to which an antigen is attached that forms an antibody-antigen complex, wherein the antigen is processed and presented by a dendritic cell that has been contacted with the antibody-antigen complex. |
| FILED | Friday, September 16, 2011 |
| APPL NO | 13/234914 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/179.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450053 | Chandok et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Meena Chandok (Odenton, Maryland); Donna Farber (Baltimore, Maryland); Francesca Okoye (Menlo Park, California) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Meena Chandok (Odenton, Maryland); Donna Farber (Baltimore, Maryland); Francesca Okoye (Menlo Park, California) |
| ABSTRACT | In this application is described a novel, multiparameter analysis of TCR-coupled signaling and function in resting and activated naive and memory CD4 T cells, revealing a biochemical basis for immunological recall. Results reveal a novel biochemical signature imparted to memory CD4 T cells enabling efficacious responses through increased ZAP-70 expression and reduced accumulation of downstream signaling events. |
| FILED | Wednesday, September 10, 2008 |
| APPL NO | 12/733636 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/4 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450056 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Benjamin L. Miller (Penfield, New York); Tim R. Mosmann (Pittsford, New York); Robert C. Rose (Geneseo, New York); Charles R. Mace (Auburn, New York) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Benjamin L. Miller (Penfield, New York); Tim R. Mosmann (Pittsford, New York); Robert C. Rose (Geneseo, New York); Charles R. Mace (Auburn, New York) |
| ABSTRACT | A sensor chip for detecting an immune response against a virus, the sensor chip including a substrate having a surface and a plurality of virus-like particles or capsid fragments bound to discrete locations on the surface of the substrate. Detection devices containing the sensor chip and methods of detecting anti-viral immune responses are also described herein. |
| FILED | Friday, May 01, 2009 |
| APPL NO | 12/434298 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450059 | Fredricks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David N. Fredricks (Seattle, Washington); Prasanna D. Khot (Cottonwood Heights, Utah); Daisy L. Ko (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | David N. Fredricks (Seattle, Washington); Prasanna D. Khot (Cottonwood Heights, Utah); Daisy L. Ko (Seattle, Washington) |
| ABSTRACT | Provided are quantitative PCR-based compositions and methods for the diagnosis of invasive pulmonary aspergillosis (IPA) in a patient sample, such as bronchoalveolar lavage (BAL) fluid. The methods presented herein involve isolating a patient sample, optionally extracting DNA from the sample, carrying out a quantitative PCR (qPCR) reaction on the sample to generate an amplicon that includes a region of an Aspergillus spp. ribosomal RNA (rRNA) gene, and detecting the PCR amplicon. The present disclosure also provides primers and primer sets for specifically detecting an Aspergillus spp. fungal pathogen in the presence of human ribosomal DNA (rDNA). |
| FILED | Tuesday, April 27, 2010 |
| APPL NO | 12/768632 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450068 | Platts-Mills et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas A. E. Platts-Mills (Charlottesville, Virginia); Tina Hatley Merritt (Bentonville, Arkansas) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Thomas A. E. Platts-Mills (Charlottesville, Virginia); Tina Hatley Merritt (Bentonville, Arkansas) |
| ABSTRACT | The present invention provides an assay for detecting serum IgE antibody levels to cetuximab and to other proteins. The present invention further provides a method for predicting whether a subject will respond adversely to cetuximab treatment. The present further provides a method for detecting sensitivity to compounds comprising galactose-alpha-1,3-galactose. |
| FILED | Friday, February 15, 2008 |
| APPL NO | 12/527255 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/7.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450071 | Pereira |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Heloise Anne Pereira (Edmond, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Heloise Anne Pereira (Edmond, Oklahoma) |
| ABSTRACT | The present invention in one embodiment uses detection of isoforms of CAP37 as an early detection marker for a chronic inflammatory-associated disease. Chronic inflammatory-related diseases may include, for example, atherosclerosis, psoriasis, and osteoarthritis. The invention is also directed to isoforms of CAP37 protein having apparent molecular weights of about 135 kDa (±15 kDa) and about 100 kDa (±15 kDa) as assessed by SDS PAGE under reducing conditions, and their use as biomarkers for the presence of a chronic inflammatory-associated disease in a subject. The invention is also directed to monoclonal and/or polyclonal antibodies raised against such isoforms of CAP37 protein and kits and diagnostic tests comprising these antibodies. |
| FILED | Thursday, October 14, 2010 |
| APPL NO | 12/904917 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/53 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 436/811 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450079 | Kovalenko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Victor Kovalenko (Saco, Maine); Andrew E. Levin (Wellesley, Massachusetts) |
| ASSIGNEE(S) | Immunetics, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Victor Kovalenko (Saco, Maine); Andrew E. Levin (Wellesley, Massachusetts) |
| ABSTRACT | The invention relates to a colorimetric method for detecting bacterial or fungal pathogens by detecting peptidoglycan or (1-3)-β-D-glucan in a sample. |
| FILED | Tuesday, October 06, 2009 |
| APPL NO | 12/574590 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450085 | Montelione et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gaetano T. Montelione (Highland Park, New Jersey); Masayori Inouye (New Brunswick, New Jersey); Yuefeng Tang (Highland Park, New Jersey); Monica Roth (New York, New York); William Schneider (Hamilton, New Jersey) |
| ASSIGNEE(S) | University of Medicine and Dentistry of New Jersey (Somerset, New Jersey); Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Gaetano T. Montelione (Highland Park, New Jersey); Masayori Inouye (New Brunswick, New Jersey); Yuefeng Tang (Highland Park, New Jersey); Monica Roth (New York, New York); William Schneider (Hamilton, New Jersey) |
| ABSTRACT | Disclosed herein is a set of E. coli single-protein production (SPP) technologies with protein NMR (SPP-NMR) for (i) using isotope-enriched membrane proteins produced with the SPP system in screening detergent conditions suitable for purification and/or three-dimensional structure analysis without the requirement for protein purification, (ii) producing 2H, 13C, 15N enriched proteins suitable for high throughput and membrane protein NMR studies, and (iii) labeling with 13C—15N specific peptide bonds in proteins (referred to herein as SPP-PBL). |
| FILED | Monday, March 17, 2008 |
| APPL NO | 12/531447 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450089 | Ward et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael D. Ward (New York, New York); Jeffrey D. Rimer (Houston, Texas) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Michael D. Ward (New York, New York); Jeffrey D. Rimer (Houston, Texas) |
| ABSTRACT | A method of preventing or inhibiting L-cystine crystallization using the compounds of formula I is disclosed. R1a—O-(-A-L-)m-A-O—R1b I, wherein A, L, R1a, R1b, and m are as described herein. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of conditions that are causally related to L-cystine crystallization, such as comprising (but not limited to) kidney stones. |
| FILED | Tuesday, November 23, 2010 |
| APPL NO | 12/953096 |
| ART UNIT | 1616 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/113 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450107 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Feng Zhang (Cambridge, Massachusetts); Le Cong (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Le Cong (Cambridge, Massachusetts) |
| ABSTRACT | The invention relates to methods of altering expression of a genomic locus of interest or specifically targeting a genomic locus of interest in an animal cell, which may involve contacting the genomic locus with a non-naturally occurring or engineered composition that includes a deoxyribonucleic acid (DNA) binding polypeptide having a N-terminal capping region, a DNA binding domain comprising at least five or more Transcription activator-like effector (TALE) monomers and at least one or more half-monomers specifically ordered to target the genomic locus of interest, and a C-terminal capping region, wherein the polypeptide includes at least one or more effector domains, and wherein the polypeptide is encoded by and translated from a codon optimized nucleic acid molecule so that the polypeptide preferentially binds to the DNA of the genomic locus. |
| FILED | Thursday, September 06, 2012 |
| APPL NO | 13/604945 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450108 | Boyce |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven T. Boyce (Cincinnati, Ohio) |
| ASSIGNEE(S) | University of Cincinnati (Cincinnati, Ohio); Shriners Hospitals for Children (Tampa, Florida) |
| INVENTOR(S) | Steven T. Boyce (Cincinnati, Ohio) |
| ABSTRACT | A device, and method of making the device, capable of therapeutic treatment and/or for in vitro testing of human skin. The device may be used on skin wounds for burned, injured, or diseased skin, and provides structures and functions as in normal uninjured skin, such as barrier function, which is a definitive property of normal skin. The device contains cultured dermal and epidermal cells on a biocompatible, biodegradable reticulated matrix. All or part of the cells may be autologous, from the recipient of the cultured skin device, which advantageously eliminates concerns of tissue compatibility. The cells may also be modified genetically to provide one or more factors to facilitate healing of the engrafted skin replacement, such as an angiogenic factor to stimulate growth of blood vessels. The inventive device is easy to handle and manipulate for surgical transplant, can be made into large sheets to minimize the number of grafts required to cover a large surface area to be treated, and can be produced within the time frame to treat a burned individual requiring a skin graft. |
| FILED | Friday, June 18, 2010 |
| APPL NO | 12/818302 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/347 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450247 | Peelle et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Beau R. Peelle (Manhattan Beach, California); Angela M. Belcher (Cambridge, Massachusetts); Karl Dane Wittrup (Cambridge, Massachusetts); Eric Krauland (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Beau R. Peelle (Manhattan Beach, California); Angela M. Belcher (Cambridge, Massachusetts); Karl Dane Wittrup (Cambridge, Massachusetts); Eric Krauland (Cambridge, Massachusetts) |
| ABSTRACT | Eukaryotic cell display libraries for use in panning processes comprising expressed biomolecules for specific and selective binding and enrichment to solid material surfaces including, for example, metal, magnetic, and semiconducting surfaces. Display can be regulated. Peptide and protein display on yeast cells are preferred. Solid materials can be fabricated in the presence of cell display libraries which have been subjected to panning against the solid materials. Nanoparticles can be grown in the presence of the biomolecules from reactive precursors. The nanoparticles can show quantum confinement effects. Self-healing films can be prepared. |
| FILED | Monday, February 07, 2005 |
| APPL NO | 11/051481 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Combinatorial chemistry technology: Method, library, apparatus 56/14 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450277 | Chapman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Edwin R. Chapman (Madison, Wisconsin); Min Dong (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Edwin R. Chapman (Madison, Wisconsin); Min Dong (Madison, Wisconsin) |
| ABSTRACT | The present invention is based on the identification of synaptic vessel glycoprotein SV2 as the BoNT/A receptor and the further identification of various BoNT/A-binding fragments of SV2. The disclosure here provides new tools for diagnosing and treating botulism. |
| FILED | Thursday, January 27, 2011 |
| APPL NO | 13/014971 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/17.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450285 | McCoy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sharon L. McCoy (Portland, Oregon); Steven H. Hefeneider (Portland, Oregon) |
| ASSIGNEE(S) | 13Therapeutics, Inc. (Portland, Oregon) |
| INVENTOR(S) | Sharon L. McCoy (Portland, Oregon); Steven H. Hefeneider (Portland, Oregon) |
| ABSTRACT | Peptides for the treatment of inflammation, and therapeutic uses and methods of using the same are disclosed. Peptides including a transducing sequence are effective for inhibiting cytokine activity and TNF-α secretion through interaction with toll-like receptors. Experiments are described illustrating the efficacy of the compounds in treating otitis media. |
| FILED | Friday, June 04, 2010 |
| APPL NO | 12/794185 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450293 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Roger A. Jones (Martinsville, New Jersey); Elizabeth Veliath (Piscataway, New Jersey) |
| ASSIGNEE(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Roger A. Jones (Martinsville, New Jersey); Elizabeth Veliath (Piscataway, New Jersey) |
| ABSTRACT | The invention provides analogs cyclic diguanosine monophosphate (c-di-GMP) having different substituents at the guanine C8 position. |
| FILED | Wednesday, August 10, 2011 |
| APPL NO | 13/207169 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/48 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450297 | Rosenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert D. Rosenberg (Cambridge, Massachusetts); Kuberan Balagurunathan (Salt Lake City, Utah) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert D. Rosenberg (Cambridge, Massachusetts); Kuberan Balagurunathan (Salt Lake City, Utah) |
| ABSTRACT | The present invention provides methods for the production of N-deacetylate N-sulfate derivatives of non-sulfated N-acetyl heparosan (HS) polysaccharides, compounds thus obtained and compositions comprising same. This invention also provides applications of N-deacetylate N-sulfate derivatives of non-sulfated N-acetyl heparosan (HS) polysaccharides, and compositions comprising same, for use in controlling coagulation and treating thrombosis. |
| FILED | Tuesday, August 16, 2005 |
| APPL NO | 11/204391 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/56 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450298 | Mahon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kerry Peter Mahon (Cambridge, Massachusetts); Kevin Thomas Love (Cambridge, Massachusetts); Christopher G. Levins (Somerville, Massachusetts); Kathryn Ann Whitehead (Somerville, Massachusetts); Robert S. Langer (Newton, Massachusetts); Daniel Griffith Anderson (Sudbury, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Kerry Peter Mahon (Cambridge, Massachusetts); Kevin Thomas Love (Cambridge, Massachusetts); Christopher G. Levins (Somerville, Massachusetts); Kathryn Ann Whitehead (Somerville, Massachusetts); Robert S. Langer (Newton, Massachusetts); Daniel Griffith Anderson (Sudbury, Massachusetts) |
| ABSTRACT | Aminoalcohol lipidoids are prepared by reacting an amine with an epoxide-terminated compound are described. Methods of preparing aminoalcohol lipidoids from commercially available starting materials are also provided. Aminoalcohol lipidoids may be prepared from racemic or stereochemically pure epoxides. Aminoalcohol lipidoids or salts forms thereof are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the amino moiety of these aminoalcohol lipidoid compounds, they are particularly suited for the delivery of polynucleotides. Complexes, micelles, liposomes or particles containing the inventive lipidoids and polynucleotide have been prepared. The inventive lipidoids may also be used in preparing microparticles for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings. |
| FILED | Wednesday, March 03, 2010 |
| APPL NO | 12/716732 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/80 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450307 | Sargent et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bruce J. Sargent (Albany, New York); Henry Pauls (Oakville, Canada); Judd M. Berman (Toronto, Canada); Jailall Ramnauth (Brampton, Canada); Peter Sampson (Oakville, Canada); Andras Toro (Toronto, Canada); Fernando J. Martin (Lancaster, Pennsylvania); Matthew D. Surman (Albany, New York); Helene Y. Decornez (Clifton Park, New York); David D. Manning (Duanesburg, New York) |
| ASSIGNEE(S) | Affinium Pharmaceuticals, Inc. (Toronto, Canada) |
| INVENTOR(S) | Bruce J. Sargent (Albany, New York); Henry Pauls (Oakville, Canada); Judd M. Berman (Toronto, Canada); Jailall Ramnauth (Brampton, Canada); Peter Sampson (Oakville, Canada); Andras Toro (Toronto, Canada); Fernando J. Martin (Lancaster, Pennsylvania); Matthew D. Surman (Albany, New York); Helene Y. Decornez (Clifton Park, New York); David D. Manning (Duanesburg, New York) |
| ABSTRACT | In part, the present invention is directed to antibacterial compounds. |
| FILED | Monday, June 06, 2005 |
| APPL NO | 11/628569 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/221 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450325 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arthur M. Brown (Brecksville, Ohio); Naresh Chand (Gaithersburg, Maryland) |
| ASSIGNEE(S) | ChanRx Corp. (Cleveland, Ohio); The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Arthur M. Brown (Brecksville, Ohio); Naresh Chand (Gaithersburg, Maryland) |
| ABSTRACT | Disclosed are methods of preventing or treating cardiac arrhythmia comprising administering to a mammal in need thereof, such as a human, an effective amount of vanoxerine (GBR 12909) or a pharmaceutically acceptable salt, derivative or metabolite thereof. |
| FILED | Monday, June 13, 2011 |
| APPL NO | 13/158791 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/255.40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450333 | Nunnari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jodi Nunnari (Davis, California); Ann Cassidy-Stone (Davis, California); Mark Kurth (Davis, California) |
| ASSIGNEE(S) | The Regents of The University of California (Oakland, California) |
| INVENTOR(S) | Jodi Nunnari (Davis, California); Ann Cassidy-Stone (Davis, California); Mark Kurth (Davis, California) |
| ABSTRACT | The present invention provides compounds capable of regulating apoptosis, e.g., via regulating mitochondrial fission or fusion. The present invention also provides methods of screening for compounds capable of regulating apoptosis and methods of treating conditions association with apoptosis. |
| FILED | Friday, February 08, 2008 |
| APPL NO | 12/028536 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/266.310 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450334 | Vasioukhin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Valeri I. Vasioukhin (Seattle, Washington); John R. Chevillet (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington) |
| INVENTOR(S) | Valeri I. Vasioukhin (Seattle, Washington); John R. Chevillet (Seattle, Washington) |
| ABSTRACT | Compositions and methods are provided for preventing or attenuating cancer progression or blocking metastasis in prostate cancer and other cancers (e.g., ovarian carcinoma, endometrial cancer, renal cell carcinoma) that are characterized by overexpression of the type II cell surface serine protease hepsin, based on the discovery of multiple disclosed compounds having activity as specific hepsin inhibitors. |
| FILED | Thursday, May 21, 2009 |
| APPL NO | 12/997465 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/268 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450364 | Lephart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Edwin Douglas Lephart (Orem, Utah); Trent D. Lund (Wheaton, Illinois); Kenneth David Reginald Setchell (Cincinnati, Ohio); Robert J. Handa (Fort Collins, Colorado) |
| ASSIGNEE(S) | Brigham Young University (Provo, Utah); Colorado State University Research Foundation (Fort Collins, Colorado); Children's Hospital Medical Center of Cincinnati, Ohio (Cincinnati, Ohio) |
| INVENTOR(S) | Edwin Douglas Lephart (Orem, Utah); Trent D. Lund (Wheaton, Illinois); Kenneth David Reginald Setchell (Cincinnati, Ohio); Robert J. Handa (Fort Collins, Colorado) |
| ABSTRACT | Equol (7-hydroxy-3(4′hydroxyphenyl)-chroman), the major metabolite of the phytoestrogen daidzein, specifically binds and blocks the hormonal action of 5α-dihydrotestosterone (DHT) in vitro and in vivo. Equol can bind circulating free DHT and sequester it from the androgen receptor, thus altering growth and physiological hormone responses that are regulated by androgens. These data suggest a novel model to explain equol's biological properties. The significance of equol's ability to specifically bind and sequester DHT from the androgen receptor have important ramifications in health and disease and may indicate a broad and important usage for equol in the treatment and prevention of androgen-mediated pathologies. Thus, equol can specifically bind DHT and prevent DHT's biological actions in physiological and pathophysiological processes. |
| FILED | Monday, April 09, 2012 |
| APPL NO | 13/442466 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/456 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450366 | McIntosh |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Matthias C. McIntosh (Fayetteville, Arkansas) |
| ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | Matthias C. McIntosh (Fayetteville, Arkansas) |
| ABSTRACT | Isobenzofuran analogs of sclerophytin A are prepared in a highly concise fashion via an aldol-cycloaldol sequence. The analogs exhibit IC50's as low as 1 μM in growth inhibitory studies against KB3 cells using an MTT assay. Preferred analogs have one of the following structural formulas, where R is hydrogen or a substituted or unsubstituted lower alkyl group and Ar is a substituted or unsubstituted aryl group. |
| FILED | Wednesday, June 30, 2010 |
| APPL NO | 12/803611 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/470 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450368 | Wilks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Angela Wilks (Baltimore, Maryland); Alexander MacKerrel, Jr. (Baltimore, Maryland); Lena Furci (Grove City, Ohio); Pedro Lopes (Baltimore, Maryland) |
| ASSIGNEE(S) | University of Maryland, Baltimore (Baltimore, Maryland) |
| INVENTOR(S) | Angela Wilks (Baltimore, Maryland); Alexander MacKerrel, Jr. (Baltimore, Maryland); Lena Furci (Grove City, Ohio); Pedro Lopes (Baltimore, Maryland) |
| ABSTRACT | Inhibitors of microbial heme oxygenase and their use for treatment of microbial infections and bioremediation. The inhibitors of microbial heme oxygenase are useful against a new class of antimicrobial agents to target infections that are persistently difficult to combat with the current spectrum of antimicrobial agents. Screening methods for selecting inhibitors of microbial heme oxygenase. |
| FILED | Tuesday, July 24, 2007 |
| APPL NO | 12/374964 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/557 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450374 | Koh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John Tze-tzun Koh (West Grove, Pennsylvania); Paula Lynn McGinley (Langhorne, Pennsylvania); Hongmu Pan (Newark, Delaware); Robert Sikes (Newark, Delaware) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | John Tze-tzun Koh (West Grove, Pennsylvania); Paula Lynn McGinley (Langhorne, Pennsylvania); Hongmu Pan (Newark, Delaware); Robert Sikes (Newark, Delaware) |
| ABSTRACT | Disclosed herein are novel antagonists of the androgen receptor and androgen receptor mutations associated with clinical failure of currently prescribed anti-androgens and use of said antagonists in the treatment of conditions associated with inappropriate activation of the androgen receptor. |
| FILED | Tuesday, June 29, 2010 |
| APPL NO | 12/826242 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/618 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450454 | Yan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shi Du Yan (Tenafly, New Jersey); David M. Stern (Cincinnati, Ohio); Joyce W. Lustbader (Tenafly, New Jersey); Hao Wu (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Shi Du Yan (Tenafly, New Jersey); David M. Stern (Cincinnati, Ohio); Joyce W. Lustbader (Tenafly, New Jersey); Hao Wu (New York, New York) |
| ABSTRACT | This invention provides methods, compositions and articles of manufacture for inhibiting binding between Aβ protein and ABAD in cells. Uses of this invention include, for example, treating Alzheimer's disease; reducing free radical generation, DNA fragmentation, and cytochrome C release in cells; and preserving cell viability by preventing LDH release from a cell. |
| FILED | Thursday, January 13, 2011 |
| APPL NO | 13/006309 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450468 | Niu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Li Niu (Loudonville, New York); Zhen Huang (Albany, New York); Hua Shi (Ithaca, New York); John T. Lis (Ithaca, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Albany, New York); Cornell University (Ithaca, New York) |
| INVENTOR(S) | Li Niu (Loudonville, New York); Zhen Huang (Albany, New York); Hua Shi (Ithaca, New York); John T. Lis (Ithaca, New York) |
| ABSTRACT | The present invention relates to novel nucleic acid ligands or aptamers that bind to and inhibit the activation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors. Also disclosed is a novel combination of technologies, i.e., SELEX and laser pulse photolysis for the selection and screening of aptamers that inhibit receptor function and are useful therefore, in the treatment of diseases associated with excessive activation of ionotropic glutamate receptors. |
| FILED | Monday, December 12, 2011 |
| APPL NO | 13/323161 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/22.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450473 | Sullivan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jack M. Sullivan (Hamburg, New York) |
| ASSIGNEE(S) | The Research Foundation of State University of New York (Amherst, New York) |
| INVENTOR(S) | Jack M. Sullivan (Hamburg, New York) |
| ABSTRACT | Provided are compositions and methods for therapy of macular degeneration including dry age-related macular degeneration (dAMD), juvenile macular degenerations (JMDs) where toxic retinoids are known to accumulate as part of the pathogenesis, such as Stargardt disease, and Best disease, and neovascular wet age-related macular degeneration. The method entails administering to an individual in need of therapy for macular degeneration a first polynucleotide that can facilitate a reduction in the amount of rod opsin (RHO) mRNA in the individual; or a second polynucleotide that can facilitate a reduction in the amount of RPE65 mRNA in the individual; or a combination thereof. The polynucleotides of the invention are hammerhead ribozymes or shRNAs. The polynucleotides target a sequence in RHO mRNA or RPE65 mRNA and facilitate reduction in the target mRNA via ribozymatic cleavage of the target, or by hybridization to the target, which leads to RNAi mediated degradation of the target mRNA. |
| FILED | Friday, April 30, 2010 |
| APPL NO | 13/266219 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450481 | Masliah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eliezer Masliah (San Diego, California); Igor Tsigelny (San Diego, California); Wolfgang Wrasidlo (La Jolla, California); Edward Rockenstein (Chula Vista, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eliezer Masliah (San Diego, California); Igor Tsigelny (San Diego, California); Wolfgang Wrasidlo (La Jolla, California); Edward Rockenstein (Chula Vista, California) |
| ABSTRACT | The invention provides compositions comprising protein aggregation inhibitors, and pharmaceutical compositions comprising them, and methods for making and using them, including methods for preventing, reversing, slowing or inhibiting protein aggregation, e.g., for treating diseases that are characterized by protein aggregation—including some degenerative neurological diseases such as Parkinson's disease. In one aspect, the compositions of the invention specifically target synuclein, beta-amyloid and/or tau protein aggregates, and the methods of the invention can be used to specifically prevent, reverse, slow or inhibit synuclein, beta-amyloid and/or tau protein aggregation. In alternative embodiments, the compositions and methods of the invention, are used to treat, prevent or ameliorate (including slowing the progression of) degenerative neurological diseases related to or caused by protein aggregation, e.g., synuclein, beta-amyloid and/or tau protein aggregation. In one aspect, compositions and methods of this invention are used to treat, prevent or ameliorate (including slowing the progression of) Parkinson's disease, Alzheimer's Disease (AD), Lewy body disease (LBD) and Multiple system atrophy (MSA). |
| FILED | Friday, June 13, 2008 |
| APPL NO | 12/602689 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 544/279 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450674 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Changhuei Yang (Pasadena, California); Charles DiMarzio (Cambridge, Massachusetts); Meng Cui (Ashburn, Virginia); Ying Min Wang (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Changhuei Yang (Pasadena, California); Charles DiMarzio (Cambridge, Massachusetts); Meng Cui (Ashburn, Virginia); Ying Min Wang (Pasadena, California) |
| ABSTRACT | A light microscope for imaging a sample containing one or more fluorescent agents, comprising a source for generating acoustic waves that are focused at a focus in the sample, wherein the acoustic waves frequency shift a frequency of light passing through the focus, thereby creating a frequency shifted light beam; at least one spatial light modulator (SLM) positioned to illuminate the sample with an output beam that is an optical phase conjugate of the frequency shifted light beam, wherein the output beam is a reflection of a first reference beam off one or more pixels of the SLM, and the pixels are for modulating the first reference beam to create the output beam; and a detector positioned to detect fluorescence generated by the output beam exciting the fluorescent agents at the focus in the sample, thereby imaging the sample. |
| FILED | Wednesday, November 10, 2010 |
| APPL NO | 12/943841 |
| ART UNIT | 2878 — Optics |
| CURRENT CPC | Radiant energy 250/208.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451693 | Nikoozadeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Amin Nikoozadeh (Burlingame, California); Butrus T. Khuri-Yakub (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| INVENTOR(S) | Amin Nikoozadeh (Burlingame, California); Butrus T. Khuri-Yakub (Palo Alto, California) |
| ABSTRACT | A compression post capacitive micromachined ultrasonic transducer (CMUT) is provided. The compression post CMUT includes a first electrode, a top conductive layer having a pattern of post holes, a moveable mass that includes the first electrode. The compression post CMUT further includes an operating gap disposed between the top surface of the top conductive layer and a bottom surface of the moveable mass, a pattern of compression posts, where a proximal end the compression post is connected perpendicularly to a bottom surface of the moveable mass, where the pattern of compression posts span through the pattern of post holes. The top conductive layer includes the second electrode that is electronically insulated from the first electrode, where the pattern of compression posts compress to provide a restoring force in a direction that is normal to the bottom surface of the moveable mass. |
| FILED | Friday, August 20, 2010 |
| APPL NO | 12/806763 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0292 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452061 | Liang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jerome Z. Liang (Stony Brook, New York); Zigang Wang (Knoxville, Tennessee) |
| ASSIGNEE(S) | The Research Foundation of State University of New York (New York, New York) |
| INVENTOR(S) | Jerome Z. Liang (Stony Brook, New York); Zigang Wang (Knoxville, Tennessee) |
| ABSTRACT | A method for electronically cleansing a virtual object formed from acquired image data converted to a plurality of volume elements is provided. The present method allows individual volume elements, or voxels, to represent more than one material type. The method includes defining a partial volume image model for volume elements representing a plurality of material types based, at least in part, on the measured intensity value of the volume element. The material mixture for each of the volume elements representing a plurality of material types can be estimated using the observed intensity values and the defined partial volume image model. The volume elements representing a plurality of material types can then be classified in accordance with the estimated material mixture. For electronic colon cleansing, the method includes removing at least one classification of volume elements when displaying the virtual object. |
| FILED | Wednesday, November 29, 2006 |
| APPL NO | 12/095645 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452546 | Lathrop |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel K Lathrop (San Diego, California) |
| ASSIGNEE(S) | Electronic Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Daniel K Lathrop (San Diego, California) |
| ABSTRACT | A method of processing sequencing data obtained with a polymer sequencing system identifies the most likely monomer sequence of a polymer, regardless of stochastic variations in recorded signals. Polymer sequencing data is recorded and two or more distinct series of pore blocking signals for a section of the polymer are recorded. A value is assigned to each series of pore blocking signals to obtain multiple trial sequences. The probability that each of the trial sequences could have resulting in all of trial sequences is calculated to determine a monomer sequence with the highest probability of resulting in all of the trial sequences, termed the first iteration sequence. The first iteration sequence is systematically altered to maximize the combined probability of the first iteration sequence leading to all the trial sequences in order to obtain a most likely sequence of monomers of the polymer. |
| FILED | Monday, November 09, 2009 |
| APPL NO | 12/614782 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 08448419 | Demmons et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nathaniel Demmons (Mason, New Hampshire); Vlad Hruby (Newton, Massachusetts); Douglas Spence (Brookline, Massachusetts); Thomas Roy (Auburndale, Massachusetts) |
| ASSIGNEE(S) | Busek Company, Inc. (Natick, Massachusetts) |
| INVENTOR(S) | Nathaniel Demmons (Mason, New Hampshire); Vlad Hruby (Newton, Massachusetts); Douglas Spence (Brookline, Massachusetts); Thomas Roy (Auburndale, Massachusetts) |
| ABSTRACT | An electrospray source useful for a variety of applications and including an emitter with a porous media flow distributor having a surface forming multiple Taylor cones. A casing about the porous media flow distributor controls the direction of a working fluid through the porous media. An extractor is at a potential different than the emitter for forming the Taylor cones. A guard electrode is disposed between the emitter and the extractor and is at or above the potential of the emitter for shaping the electric field formed between the emitter and the extractor. |
| FILED | Monday, August 18, 2008 |
| APPL NO | 12/228909 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/202 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08448532 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Martin (Louisville, Kentucky); Kevin Walsh (Louisville, Kentucky); Julia Aebersold (Floyd Knobs, Indiana); R. Andrew McGill (Lorton, Virginia); Stanley V. Stepnowski (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia); University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Michael Martin (Louisville, Kentucky); Kevin Walsh (Louisville, Kentucky); Julia Aebersold (Floyd Knobs, Indiana); R. Andrew McGill (Lorton, Virginia); Stanley V. Stepnowski (Alexandria, Virginia) |
| ABSTRACT | An analyte collection system device includes an active area that includes a plurality of perforations extending therethrough. The plurality of perforations are arranged to permit passage of an analyte fluid flow through the microscale plate. A heating element is provided for heating the active area, and a thermal distribution layer is disposed over at least a portion of the active area. For cooling the active area at or below an ambient temperature, an active cooler is provided. |
| FILED | Wednesday, March 18, 2009 |
| APPL NO | 12/406756 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/863.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08448560 | Gonzalez |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rene′ G. Gonzalez (Southfield, Michigan) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Rene′ G. Gonzalez (Southfield, Michigan) |
| ABSTRACT | A reactive armor that includes a tube; end caps installed on the ends of the tube; a plurality of impacters included inside of the tube; explosive included between the impacters and between the end caps and the impacters; and one or more passages, wherein the passages provide communication such that when a threat ruptures the tube, the propellant is progressively ignited from the rupture; and, except for the rupture that results from intrusion of the threat, the tube remains essentially intact. |
| FILED | Wednesday, May 11, 2011 |
| APPL NO | 13/105507 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ordnance 089/36.170 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08448573 | Dutton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brian Dwayne Dutton (Ridgecrest, California); John Kevin Kandell (Ridgecrest, California); Gabriel Henry Soto (Ridgecrest, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Brian Dwayne Dutton (Ridgecrest, California); John Kevin Kandell (Ridgecrest, California); Gabriel Henry Soto (Ridgecrest, California) |
| ABSTRACT | A multiple warhead fuzing apparatus including a first warhead and a second warhead. Operation/detonation of the first and second warheads is controlled using safe and arming logic and an onboard weapon computer that communicates triggering and fire signal parameters to fire signal logic located on the weapon. For a hard target application, the initiation module(s) of each warhead will initiate when commanded by the warhead's fuze after specific criteria has been satisfied, as determined by the fuze programming from the weapon computer. Soft target applications will require the warheads to initiate simultaneously after a delay from impact. The large area target settings will initiate all warheads upon receipt of a fire command from the weapon computer or height of burst sensor. |
| FILED | Thursday, September 23, 2010 |
| APPL NO | 12/889135 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/206 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08448574 | Robinson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles H. Robinson (Potomac, Maryland); Robert H. Wood (Laurel, Maryland); Mark R. Gelak (Columbia, Maryland); Thinh Q. Hoang (Beltsville, Maryland); Gabriel L. Smith (Odenton, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Charles H. Robinson (Potomac, Maryland); Robert H. Wood (Laurel, Maryland); Mark R. Gelak (Columbia, Maryland); Thinh Q. Hoang (Beltsville, Maryland); Gabriel L. Smith (Odenton, Maryland) |
| ABSTRACT | An ultra-miniature, electro-mechanical, MEMS type safe and arming (S&A) device for medium- or large-artillery rounds, including, three sequenced S&A interlocks: a setback slider which provides a 1st interlock with respect to an arming slider which moves due to the round's spin; a stop and release mechanism that holds the arming slider until a release command signal is initiated by the fuze circuit, triggering a spot charge which generates an expanding gas wave that flexes the latch arm from contact with the safety catch, unlocking the 2nd interlock, thereby freeing the arming slider to continue its motion into an arming position, unlocking the 3rd interlock, and aligning the parts of the firetrain within the device, such that upon signal from the fuze circuit to an output charge, the device will ignite the acceptor charge within the round. |
| FILED | Tuesday, March 06, 2012 |
| APPL NO | 13/412915 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/235 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08448612 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kenneth Jay Wilson (Ridgecrest, California); Travis Shane Laker (Tremonton, Utah); Ephraim Berk Washburn (Ridgecrest, California); Alice Irene Atwood (Ridgecrest, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth Jay Wilson (Ridgecrest, California); Travis Shane Laker (Tremonton, Utah); Ephraim Berk Washburn (Ridgecrest, California); Alice Irene Atwood (Ridgecrest, California) |
| ABSTRACT | A propane fueled combustor for providing a controlled heat flux environment of twenty to two hundred kilowatts per square meter. The combustor has the capability of generating a repeatable and quantifiable environment in which to evaluate a response of an energetic material to a fast cook off hazard, such as a liquid fuel fire. |
| FILED | Thursday, April 05, 2007 |
| APPL NO | 11/789115 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Internal-combustion engines 123/3 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08448760 | Houtsma |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gary J. Houtsma (Denville, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Gary J. Houtsma (Denville, New Jersey) |
| ABSTRACT | A buffering, energy absorbing, system has tapered grooves within either the inner surface of a cylindrical main body or along the sides of a piston head to allow fluid flow, where the tapered grooves increasingly or decreasingly restrict the flow of fluid between the inside of the main body and an accumulator. |
| FILED | Thursday, August 30, 2007 |
| APPL NO | 11/900136 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Brakes 188/284 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449125 | Tischler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jonathan R. Tischler (Sharon, Massachusetts); Michael Scott Bradley (Quincy, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jonathan R. Tischler (Sharon, Massachusetts); Michael Scott Bradley (Quincy, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts) |
| ABSTRACT | A critically coupled optical resonator absorbs greater than 95% of incident light of the critical wavelength with an absorber layer less than 10 nm thick. |
| FILED | Wednesday, February 14, 2007 |
| APPL NO | 12/162892 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical: Systems and elements 359/614 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449520 | Pepper et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Clinton B. Pepper (West Linn, Oregon); Simon J. McCarthy (Portland, Oregon); Lisa A. Buckley (Portland, Oregon); Eric K. Meyer (Hillsboro, Oregon) |
| ASSIGNEE(S) | HemCon Medical Technologies Inc. (Portland, Oregon) |
| INVENTOR(S) | Clinton B. Pepper (West Linn, Oregon); Simon J. McCarthy (Portland, Oregon); Lisa A. Buckley (Portland, Oregon); Eric K. Meyer (Hillsboro, Oregon) |
| ABSTRACT | A flexible container receives a liquid material, which is freeze-dried in situ within the flexible container. A gas permeable material that is separate from the flexible container provides gas transport for sublimation during drying and lyophilization. The gas permeable portion of the system can be isolated and removed from the flexible container post-lyophilzation The freeze-dried material is stored in the flexible container until administration is necessary. The flexible container receives a reconstituting liquid for mixing with the freeze-dried material, and conveys the reconstituted freeze-dried material from the flexible container for administration to an individual. |
| FILED | Friday, August 15, 2008 |
| APPL NO | 12/228745 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Surgery 64/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449624 | Evans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher O. Evans (Amherst, New Hampshire); N. Christopher Perry (Manchester, New Hampshire); Dirk Albertus van der Merwe (Dunbarton, New Hampshire); Christopher C. Langenfeld (Nashua, New Hampshire); John Matthew Kerwin (Manchester, New Hampshire); Stewart M. Coulter (Bedford, New Hampshire); Stanley B. Smith, III (Raymond, New Hampshire); Keith David Violette (Sandown, New Hampshire); Steven W. Nickson (Derry, New Hampshire); Thomas S. Schnellinger (North Andover, Massachusetts); Alexander H. Muller (Manchester, New Hampshire); Gerald Michael Guay (Greenville, New Hampshire) |
| ASSIGNEE(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| INVENTOR(S) | Christopher O. Evans (Amherst, New Hampshire); N. Christopher Perry (Manchester, New Hampshire); Dirk Albertus van der Merwe (Dunbarton, New Hampshire); Christopher C. Langenfeld (Nashua, New Hampshire); John Matthew Kerwin (Manchester, New Hampshire); Stewart M. Coulter (Bedford, New Hampshire); Stanley B. Smith, III (Raymond, New Hampshire); Keith David Violette (Sandown, New Hampshire); Steven W. Nickson (Derry, New Hampshire); Thomas S. Schnellinger (North Andover, Massachusetts); Alexander H. Muller (Manchester, New Hampshire); Gerald Michael Guay (Greenville, New Hampshire) |
| ABSTRACT | A prosthetic arm apparatus including a plurality of segments that provide a user of the prosthetic arm apparatus with substantially the same movement capability and function as a human arm. The segments are connectable to one another and connectable to a prosthetic support apparatus that may be adorned by the user. Each segment of the plurality of segments provides a portion of the movement capability, enabling the plurality of connected segments connected to the harness mount to provide substantially the same movement capability as that lacking in the user. |
| FILED | Tuesday, February 16, 2010 |
| APPL NO | 12/706609 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Prosthesis 623/62 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449672 | Feigelson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Boris N. Feigelson (Springfield, Virginia); Richard L. Henry (Great Falls,, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Boris N. Feigelson (Springfield, Virginia); Richard L. Henry (Great Falls,, Virginia) |
| ABSTRACT | This disclosure pertains to a process for making single crystal Group III nitride, particularly gallium nitride, at low pressure and temperature, in the region of the phase diagram of Group III nitride where Group III nitride is thermodynamically stable comprises a charge in the reaction vessel of (a) Group III nitride material as a source, (b) a barrier of solvent interposed between said source of Group III nitride and the deposition site, the solvent being prepared from the lithium nitride (Li3N) combined with barium fluoride (BaF2), or lithium nitride combined with barium fluoride and lithium fluoride (LiF) composition, heating the solvent to render it molten, dissolution of the source of GaN material in the molten solvent and following precipitation of GaN single crystals either self seeded or on the seed, maintaining conditions and then precipitating out. |
| FILED | Friday, April 25, 2008 |
| APPL NO | 12/149051 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449838 | Shaikh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kashan Ali Shaikh (Clifton Park, New York); Christopher Michael Puleo (Glenville, New York); Jun Xie (Niskayuna, New York); Hansong Zeng (Schenectady, New York); Li Zhu (Clifton Park, New York) |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Kashan Ali Shaikh (Clifton Park, New York); Christopher Michael Puleo (Glenville, New York); Jun Xie (Niskayuna, New York); Hansong Zeng (Schenectady, New York); Li Zhu (Clifton Park, New York) |
| ABSTRACT | A microfluidic device for batch processing magnetic bead assays and having one or more microfluidic sample channels, comprising, one or more micromagnets seated in a fixture; and an actuator; wherein a portion of each micromagnet is in releasable operative association with one or more of the microfluidic sample channels, and another portion of each micromagnet is in releasable operative association with the actuator; and methods for using the same. |
| FILED | Tuesday, July 20, 2010 |
| APPL NO | 12/839872 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/533 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450055 | Bruder et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph T. Bruder (Ijamsville, Maryland); Imre Kovesdi (Rockville, Maryland); Duncan L. McVey (Derwood, Maryland); Douglas E. Brough (Gaithersburg, Maryland); C. Richter King (Washington, District of Columbia); Denise Louise Doolan (Camp Hill, Australia); Joao Carlos Aguair (Potomac, Maryland); Daniel John Carucci (Washington, District of Columbia); Martha Sedegah (Gaithersburg, Maryland); Walter R. Weiss (Bethesda, Maryland); Keith Limbach (Gaithersburg, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Joseph T. Bruder (Ijamsville, Maryland); Imre Kovesdi (Rockville, Maryland); Duncan L. McVey (Derwood, Maryland); Douglas E. Brough (Gaithersburg, Maryland); C. Richter King (Washington, District of Columbia); Denise Louise Doolan (Camp Hill, Australia); Joao Carlos Aguair (Potomac, Maryland); Daniel John Carucci (Washington, District of Columbia); Martha Sedegah (Gaithersburg, Maryland); Walter R. Weiss (Bethesda, Maryland); Keith Limbach (Gaithersburg, Maryland) |
| ABSTRACT | The invention provides a method of identifying an antigen from a pathogen or a disease antigen comprising the use of an adenoviral vector array comprising two or more different adenoviral vectors, wherein each adenoviral vector comprises a nucleic acid sequence encoding a different antigen of a pathogen. The adenoviral vectors are administered to antigen presenting cells (APCs) in vitro or to an animal in vivo. The immunogenicity of the antigen is measured by screening for an immune response from effector T lymphocytes in vitro and by screening for the absence of pathogen-induced disease onset in vivo. |
| FILED | Friday, August 25, 2006 |
| APPL NO | 11/513439 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/5 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450434 | Ramotowski |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas S. Ramotowski (Tiverton, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Thomas S. Ramotowski (Tiverton, Rhode Island) |
| ABSTRACT | An epoxy and rubber microcomposite is formed by adding a carboxy-terminated or amine-terminated rubber component having a glass transition temperature less than zero degrees centigrade to a bisphenol A based epoxy resin component; heating the mixture to 150 degrees centigrade; cooling and curing with a suitable curing agent. A phase segregation occurs between the epoxy resin component and the rubber component to form discrete, spherical rubbery domains with the epoxy compound. Because the glass transition temperature of the rubbery domains is below zero degrees centigrade; the rubbery domains act as acoustic windows within the high-modulus epoxy compound. |
| FILED | Friday, September 14, 2012 |
| APPL NO | 13/615837 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions of Macromolecular Compounds C08L 63/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450449 | Reynolds et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John R. Reynolds (Gainesville, Florida); Pengjie Shi (Gainesville, Florida); Jianguo Mei (Greensboro, North Carolina); Chad Martin Amb (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | John R. Reynolds (Gainesville, Florida); Pengjie Shi (Gainesville, Florida); Jianguo Mei (Greensboro, North Carolina); Chad Martin Amb (Gainesville, Florida) |
| ABSTRACT | Embodiments of the invention are directed to random conjugated copolymers comprising a plurality of one or more different donor (D) repeating units and a plurality of at least one acceptor (A) repeating unit. At least one of the D units has a solubilizing substituent, statistically a portion of the A repeating units are separated from each other by only one D units and a plurality of the A unit are adjacent to one the D units having the solubilizing substituents. The random conjugated copolymers are black or colored in the neutral state and highly transmissive in the oxidized state. The random conjugated copolymers have the structure -[(D)xA]n-, where x>1 and n(x+1)≧10 or the structure -[(DA))x-(D′A)y]n-, where D represents one substituted D unit and D′ represents another D units and where x≧1, y≧1 and 2n(x+y)≧10. Other embodiments of the invention are directed to forming the -[(D)xA]n- or -[(DA)x-(D′A)y]n- random conjugated copolymers by condensation polymerizations between monomers containing complementary reactive groups. |
| FILED | Thursday, May 19, 2011 |
| APPL NO | 13/111350 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 528/377 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450468 | Niu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Li Niu (Loudonville, New York); Zhen Huang (Albany, New York); Hua Shi (Ithaca, New York); John T. Lis (Ithaca, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Albany, New York); Cornell University (Ithaca, New York) |
| INVENTOR(S) | Li Niu (Loudonville, New York); Zhen Huang (Albany, New York); Hua Shi (Ithaca, New York); John T. Lis (Ithaca, New York) |
| ABSTRACT | The present invention relates to novel nucleic acid ligands or aptamers that bind to and inhibit the activation of the α-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) subtype of ionotropic glutamate receptors. Also disclosed is a novel combination of technologies, i.e., SELEX and laser pulse photolysis for the selection and screening of aptamers that inhibit receptor function and are useful therefore, in the treatment of diseases associated with excessive activation of ionotropic glutamate receptors. |
| FILED | Monday, December 12, 2011 |
| APPL NO | 13/323161 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Organic compounds 536/22.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450609 | Clifton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher Clifton (Bloomfield, Indiana); Dean L. Jones (Bloomington, Indiana); Philip S. Mitchell (Springville, Indiana); David Myers (Bloomfield, Indiana); James M. Pruett (Montgomery, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christopher Clifton (Bloomfield, Indiana); Dean L. Jones (Bloomington, Indiana); Philip S. Mitchell (Springville, Indiana); David Myers (Bloomfield, Indiana); James M. Pruett (Montgomery, Indiana) |
| ABSTRACT | A signal interface includes a support structure having a pivotally supported cover and side wings. A latching mechanism is provided to secure the cover to the side wings in both stowed and deployed positions. |
| FILED | Friday, January 29, 2010 |
| APPL NO | 12/696778 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Electricity: Conductors and insulators 174/59 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450688 | La Lumondiere et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen La Lumondiere (Torrance, California); Terence Yeoh (Pasadena, California); Martin Siu Wo Leung (Redondo Beach, California); Neil A. Ives (Hawthorne, California); William T. Lotshaw (Rancho Palos Verdes, California); Steven C. Moss (Hermosa Beach, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Stephen La Lumondiere (Torrance, California); Terence Yeoh (Pasadena, California); Martin Siu Wo Leung (Redondo Beach, California); Neil A. Ives (Hawthorne, California); William T. Lotshaw (Rancho Palos Verdes, California); Steven C. Moss (Hermosa Beach, California) |
| ABSTRACT | Various embodiments are directed to systems and methods for imaging subsurface features of a semiconductor object comprising a first region having a first doping property and a second region having a second doping property. The semiconductor object may comprise subsurface features and material between a surface of the semiconductor object and the subsurface features. The material may have an index of refraction that is greater than an index of refraction of a surrounding medium in contact with the surface of the semiconductor object. For example, a system may comprise an imaging device comprising an objective. The imaging device may be sensitive to a first wavelength. The system may also comprise an illumination source to emit illumination substantially at the first wavelength. The illumination may be directed towards the surface of the semiconductor object at a first angle relative to a normal of the surface. The first angle is greater than an acceptance angle of the objective of the imaging device. Also, the first wavelength may have a photonic energy substantially equal to a bandgap of the first region. |
| FILED | Monday, July 25, 2011 |
| APPL NO | 13/190264 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/339.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450690 | Averitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard Averitt (Newton, Massachusetts); Xin Zhang (Medford, Massachusetts); Hu Tao (Medford, Massachusetts); Andrew Strikwerda (Jamaica Plain, Massachusetts); Willie J. Padilla (Newton, Massachusetts); Eric Shaner (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts); Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Richard Averitt (Newton, Massachusetts); Xin Zhang (Medford, Massachusetts); Hu Tao (Medford, Massachusetts); Andrew Strikwerda (Jamaica Plain, Massachusetts); Willie J. Padilla (Newton, Massachusetts); Eric Shaner (Albuquerque, New Mexico) |
| ABSTRACT | An apparatus and method are disclosed for detecting terahertz radiation at room temperature. A detecting pixel includes a sub-wavelength split-ring resonator, and is mechanically coupled to (but thermally decoupled from) a substrate via a cantilever formed from two materials that have a significant mismatch in their thermal expansion coefficients. Incident radiation causes the split-ring resonator to resonate, thereby generating heat that is transferred to the cantilever, causing the cantilever to flex. An optical readout system includes a secondary light source, such as a laser, that shines on a reflective surface on the pixel, whereby a photodiode detects the reflected light and permits calculation of a relative deflection of the pixel in the nanometer range. An exemplary detector has a noise equivalent power rating of approximately 60 pW/√Hz. |
| FILED | Tuesday, October 04, 2011 |
| APPL NO | 13/252821 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/341.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450951 | Booker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Larry Andrew Booker (Rialto, California); John Walter Gerstenberg (Lake Elsinore, California) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Larry Andrew Booker (Rialto, California); John Walter Gerstenberg (Lake Elsinore, California) |
| ABSTRACT | A system to regulate gyrotron power is configured to raise the filament voltage of a gyrotron to a standby voltage, then set the filament voltage to the normal standby voltage plus a current offset voltage before pulsing the gyrotron. The system is further configured to increase the filament voltage to a boost voltage that is higher than the standby voltage, thereby inducing a temperature increase in the cathode that offsets the cooling effect of radiating. The system is also configured to analyze a beam power of the gyrotron and adjust the filament voltage to bring a beam current within a range, and reduce the filament offset to zero such that the filament voltage is equal to the standby voltage. |
| FILED | Wednesday, December 03, 2008 |
| APPL NO | 12/327037 |
| ART UNIT | 2821 — Semiconductors/Memory |
| CURRENT CPC | Electric lamp and discharge devices: Systems 315/500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451173 | Hansen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles T. Hansen (Palos Verdes Estates, California) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Charles T. Hansen (Palos Verdes Estates, California) |
| ABSTRACT | A method for estimating a target direction of a wideband signal received on an electronically steered array includes: applying convolutional or stretch processing to spatial frequency data of the wideband signal; initializing a stabilization direction to a beam pointing direction; stabilizing the spatial frequency data to the stabilization direction; compressing the spatial frequency data to a plurality of frequency range or time bins; selecting range or time bins and forming a covariance matrix; calculating an estimated target direction using the covariance matrix; determining if a stabilization direction accuracy condition is met; recalculating the stabilization direction based on the estimated target direction if the stabilization direction accuracy condition is not met; and iteratively repeating until the stabilization direction accuracy condition is met. |
| FILED | Thursday, April 21, 2011 |
| APPL NO | 13/092073 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/422 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451189 | Fluhler |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Herbert U. Fluhler (Madison, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Herbert U. Fluhler (Madison, Alabama) |
| ABSTRACT | This disclosure demonstrates a new class of Ultra-Wide Band (UWB) AMC with very large fractional bandwidth (>100%) even at lower frequencies (<1 GHz). This new UWB AMC is enabled by recognizing that any AMC must be an antenna in order to accept the incident radiation into the circuit. Therefore, by using UWB antenna design features, one can make wide band AMCs. Additionally, by manipulation of the UWB AMC element design, a 1/frequency dependence can be obtained for instantiating the benefits of a quarter wave reflection over a large UWB bandwidth with a single physical thickness. |
| FILED | Thursday, April 15, 2010 |
| APPL NO | 12/761278 |
| ART UNIT | 2821 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Radio wave antennas 343/909 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451584 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiangyang Zhou (Miami, Florida); Juanjuan Zhou (Miami, Florida); Azzam N. Mansour (Fairfax Station, Virginia) |
| ASSIGNEE(S) | University of Miami (Miami, Florida) |
| INVENTOR(S) | Xiangyang Zhou (Miami, Florida); Juanjuan Zhou (Miami, Florida); Azzam N. Mansour (Fairfax Station, Virginia) |
| ABSTRACT | A solid state energy storage device has two electrodes, a membrane separator and a solid electrolyte having a substantially solid solvent, a salt and a mediator. The energy storage device stores electric charge by both Faradaic and non-Faradaic systems. The energy storage device may include activated carbon mixed with the electrolyte and sonicated to provide connection between the activated carbon and the mediator. The energy storage device is hot pressed to increase conductivity. The two electrodes may be asymmetric in amount of reduced and oxidized species of mediator. |
| FILED | Wednesday, March 31, 2010 |
| APPL NO | 12/751322 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/022 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451756 | Lucani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel E. Lucani (Oporto, Portugal); Milica Stojanovic (Boston, Massachusetts); Muriel Medard (Belmont, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel E. Lucani (Oporto, Portugal); Milica Stojanovic (Boston, Massachusetts); Muriel Medard (Belmont, Massachusetts) |
| ABSTRACT | Subject matter disclosed herein relates to random linear network coding schemes for reliable communications for time division duplexing channels. In at least one embodiment, a transmitter node transmits M data packets through a half-duplex link using random linear network coding. The transmitter node transmits coded packets back-to-back through the link before stopping to wait for an acknowledgement (ACK) packet. An optimal number of coded packets Ni to be transmitted in a subsequent transmission may then be determined based, at least in part, on a number of degrees of freedom (DOFs) a receiving node needs to decode the M information packets from received coded packets. |
| FILED | Tuesday, May 15, 2012 |
| APPL NO | 13/471496 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/276 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451874 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robin K. Huang (N. Billerica, Massachusetts); Joseph P. Donnelly (Carlisle, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Robin K. Huang (N. Billerica, Massachusetts); Joseph P. Donnelly (Carlisle, Massachusetts) |
| ABSTRACT | A very large mode (VLM) slab-coupled optical waveguide laser (SCOWL) is provided that includes an upper waveguide region as part of the waveguide for guiding the laser mode. The upper waveguide region is positioned in the interior regions of the VLM SCOWL. A lower waveguide region also is part of the waveguide that guides the laser mode. The lower waveguide region is positioned in an area underneath the upper waveguide region. An active region is positioned between the upper waveguide region and the lower waveguide region. The active region is arranged so etching into the VLM SCOWL is permitted to define one or more ridge structures leaving the active region unetched. One or more mode control barrier layers are positioned between said upper waveguide region and said lower waveguide region. The one or more mode control barrier layers control the fundamental mode profile and prevent mode collapse of the laser mode. The mode control barrier layers also block carrier leakage from the active region. These layers are essential to obtaining VLM SCOWLs. |
| FILED | Wednesday, December 02, 2009 |
| APPL NO | 12/629613 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/43.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452124 | Au et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kwong Wing Au (Bloomington, Minnesota); Scott McCloskey (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Kwong Wing Au (Bloomington, Minnesota); Scott McCloskey (Minneapolis, Minnesota) |
| ABSTRACT | A system for detecting motion blur may include a process in which one or more digital images taken by a camera having a shutter are obtained, wherein the digital image depicts objects in a physical world. Further, the system may estimate the motion blur in the digital image using a ratio of one or more values obtained from the projection of a 2D spectrum of the image and a Fourier transform of a sequence of the shutter used in obtaining the image. |
| FILED | Friday, April 30, 2010 |
| APPL NO | 12/771344 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/280 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452135 | Askins |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles G Askins (Upper Marlboro, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Charles G Askins (Upper Marlboro, Maryland) |
| ABSTRACT | A method of measuring fiber twist in a multi-core optical fiber bearing an FBG with polarization dependent reflectivity. The state of polarization of the launched light is adjusted until the reflected FBG wavelength is maximal, indicating that light reaching the FBG is linearly polarized, and the polarization axis of the light reaching the FBG is aligned with the slow birefringent axis of the FBG; the SOP of launched light is now measured. Bending experienced by the fiber is measured conventionally, and birefringence produced by bending of the multi-core optical fiber is calculated. A candidate amount of twist between the launch location and the FBG is proposed, and the corresponding twist-induced birefringence is calculated. When calculations show that light with the launched SOP becomes linearly polarized and aligned with the FBG after traversing a fiber section with the calculated birefringences and proposed rotation, the amount of twist has been properly identified. |
| FILED | Thursday, July 19, 2012 |
| APPL NO | 13/552948 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452254 | Strickland |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence P. Strickland (St. Petersburg, Florida) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Lawrence P. Strickland (St. Petersburg, Florida) |
| ABSTRACT | According to certain embodiments, a system comprises a main transmission line, one or more piezoelectric filters coupled to the main transmission line, and one or more sub-signal transmission lines coupled to the one or more piezoelectric filters. The main transmission line communicates a main signal from an antenna to a main receiver. Each piezoelectric filter selects a sub-signal of a specific center frequency. Each sub-signal transmission line communicates a sub-signal to a sub-signal receiver. |
| FILED | Friday, August 20, 2010 |
| APPL NO | 12/860009 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Telecommunications 455/307 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452408 | Song et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shijie Song (Tampa, Florida); Juan Sanchez-Ramos (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida); Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Shijie Song (Tampa, Florida); Juan Sanchez-Ramos (Tampa, Florida) |
| ABSTRACT | A method of treating neurological deficit in which the brain area affected is focally and precisely stimulated by the transient insertion and subsequent removal of a micro-needle. This insertion and subsequent removal of the micro-needle induces endogenous stem cells to proliferate, migrate and promote the brain's self-repair mechanisms. The micro-needle stimulation causes the birth of new neural cells within the brain as well as mobilizes bone marrow derived cells with a neuronal phenotype to migrate to the site of stimulation to repair and replace damaged neural cells. By repairing and/or replacing injured or dead cells, this approach will slow down the degenerative course of the disease and may result in reversal of symptoms. |
| FILED | Thursday, June 25, 2009 |
| APPL NO | 12/491893 |
| ART UNIT | 3766 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452546 | Lathrop |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel K Lathrop (San Diego, California) |
| ASSIGNEE(S) | Electronic Biosciences, Inc. (San Diego, California) |
| INVENTOR(S) | Daniel K Lathrop (San Diego, California) |
| ABSTRACT | A method of processing sequencing data obtained with a polymer sequencing system identifies the most likely monomer sequence of a polymer, regardless of stochastic variations in recorded signals. Polymer sequencing data is recorded and two or more distinct series of pore blocking signals for a section of the polymer are recorded. A value is assigned to each series of pore blocking signals to obtain multiple trial sequences. The probability that each of the trial sequences could have resulting in all of trial sequences is calculated to determine a monomer sequence with the highest probability of resulting in all of the trial sequences, termed the first iteration sequence. The first iteration sequence is systematically altered to maximize the combined probability of the first iteration sequence leading to all the trial sequences in order to obtain a most likely sequence of monomers of the polymer. |
| FILED | Monday, November 09, 2009 |
| APPL NO | 12/614782 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/20 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452569 | Brown |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jerry G. Brown (Bloomington, Indiana) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jerry G. Brown (Bloomington, Indiana) |
| ABSTRACT | A simulation system for predicting a likelihood of whether a target object positioned in an environment will be detected by a detection system when illuminated by a laser source. The simulation system may be used for a laser rangefinder application and a laser designator application. The simulation system may provide a detection probability of the target object at a specified range to the detection system or a plurality of detection probabilities as a function of the range to the detection system. The simulation system may provide an indication of an overlap of the beam provided by the laser source on the target object. The simulation system may determine the effect of vibration on the detection of the target object at a specified range. |
| FILED | Tuesday, March 31, 2009 |
| APPL NO | 12/414717 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/181 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452574 | Wilcox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Christopher C. Wilcox (Albuquerque, New Mexico); Sergio R Restaino (Albuquerque, New Mexico); Ty Martinez (Edgewood, New Mexico); Scott W Teare (Sorocco, New Mexico) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christopher C. Wilcox (Albuquerque, New Mexico); Sergio R Restaino (Albuquerque, New Mexico); Ty Martinez (Edgewood, New Mexico); Scott W Teare (Sorocco, New Mexico) |
| ABSTRACT | A system and method for simulating atmospheric turbulence for testing optical components. A time varying phase screen representing atmospheric turbulence is generated using Karhunen-Loeve polynomials and a splining technique for generating temporal functions of the noise factor for each Zernike mode. The phase screen is input to a liquid crystal spatial light modulator. A computer display allows the user to set geometric characteristics, and select between methods for generating atmospheric turbulence including Karhunen-Loeve polynomials, Zernike polynomials, and Frozen Seeing. |
| FILED | Tuesday, February 02, 2010 |
| APPL NO | 12/698408 |
| ART UNIT | 2123 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Structural design, modeling, simulation, and emulation 73/2 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452677 | de la Houssaye et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul de la Houssaye (San Diego, California); Jamie Pugh (San Diego, California); Donald Tien Tran (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul de la Houssaye (San Diego, California); Jamie Pugh (San Diego, California); Donald Tien Tran (San Diego, California) |
| ABSTRACT | An apparatus for assessing and predicting the health of a market comprising: a computer having a memory store; wherein the computer is disposed to receive a data stream comprising information that represents the approximate real-time value of assets; and wherein the computer is disposed to apply a data-windowing, multi-state, time-variant Markov process to transform the data stream into a current assessment of the over-all health of the market and a projected over-all health of the market. |
| FILED | Monday, March 01, 2010 |
| APPL NO | 12/715251 |
| ART UNIT | 3691 — Business Methods - Finance/Banking/ Insurance |
| CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/35 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452888 | Chan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Uman Chan (Wappingers Falls, New York); Deryck X Hong (Jackson Heights, New York); Tsai-Yang Jea (Poughkeepsie, New York); Chulho Kim (Poughkeepsie, New York); Zenon J Piatek (Poughkeepsie, New York); Hung Q Thai (Poughkeepsie, New York); Abhinav Vishnu (Kennewick, Washington); Hanhong Xue (Poughkeepsie, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Uman Chan (Wappingers Falls, New York); Deryck X Hong (Jackson Heights, New York); Tsai-Yang Jea (Poughkeepsie, New York); Chulho Kim (Poughkeepsie, New York); Zenon J Piatek (Poughkeepsie, New York); Hung Q Thai (Poughkeepsie, New York); Abhinav Vishnu (Kennewick, Washington); Hanhong Xue (Poughkeepsie, New York) |
| ABSTRACT | A message flow controller limits a process from passing a new message in a reliable message passing layer from a source node to at least one destination node while a total number of in-flight messages for the process meets a first level limit. The message flow controller limits the new message from passing from the source node to a particular destination node from among a plurality of destination nodes while a total number of in-flight messages to the particular destination node meets a second level limit. Responsive to the total number of in-flight messages to the particular destination node not meeting the second level limit, the message flow controller only sends a new packet from among at least one packet for the new message to the particular destination node while a total number of in-flight packets for the new message is less than a third level limit. |
| FILED | Thursday, July 22, 2010 |
| APPL NO | 12/841399 |
| ART UNIT | 2441 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/232 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452947 | Arimilli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ravi K. Arimilli (Austin, Texas); Satya P. Sharma (Austin, Texas); Randal C. Swanberg (Round Rock, Texas) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Ravi K. Arimilli (Austin, Texas); Satya P. Sharma (Austin, Texas); Randal C. Swanberg (Round Rock, Texas) |
| ABSTRACT | A hardware wake-and-go mechanism is provided for a data processing system. The wake-and-go mechanism looks ahead in the instruction stream of a thread for programming idioms that indicates that the thread is waiting for an event. The wake-and-go mechanism updates a wake-and-go array with a target address associated with the event for each recognized programming idiom. When the thread reaches a programming idiom, the thread goes to sleep until the event occurs. The wake-and-go array may be a content addressable memory (CAM). When a transaction appears on the symmetric multiprocessing (SMP) fabric that modifies the value at a target address in the CAM, the CAM returns a list of storage addresses at which the target address is stored. The wake-and-go mechanism associates these storage addresses with the threads waiting for an event at the target addresses, and may wake the one or more threads waiting for the event. |
| FILED | Friday, February 01, 2008 |
| APPL NO | 12/024507 |
| ART UNIT | 2183 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital processing systems: Processing architectures and instruction processing 712/220 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08453152 | Druyan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander Druyan (New York, New York); Wei Li (Beijing, China PRC); Kailash N. Marthi (Poughkeepsie, New York); Yun T. Xiang (Beijing, China PRC); Linda C. Cham (Poughkeepsie, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alexander Druyan (New York, New York); Wei Li (Beijing, China PRC); Kailash N. Marthi (Poughkeepsie, New York); Yun T. Xiang (Beijing, China PRC); Linda C. Cham (Poughkeepsie, New York) |
| ABSTRACT | A scheduler receives at least one flexible reservation request for scheduling in a computing environment comprising consumable resources. The flexible reservation request specifies a duration and at least one required resource. The consumable resources comprise at least one machine resource and at least one floating resource. The scheduler creates a flexible job for the at least one flexible reservation request and places the flexible job in a prioritized job queue for scheduling, wherein the flexible job is prioritizes relative to at least one regular job in the prioritized job queue. The scheduler adds a reservation set to a waiting state for the at least one flexible reservation request. The scheduler, responsive to detecting the flexible job positioned in the prioritized job queue for scheduling next and detecting a selection of consumable resources available to match the at least one required resource for the duration, transfers the selection of consumable resources to the reservation and sets the reservation to an active state, wherein the reservation is activated as the selection of consumable resources become available and has uninterrupted use of the selection of consumable resources for the duration by at least one job bound to the flexible reservation. |
| FILED | Tuesday, February 01, 2011 |
| APPL NO | 13/018796 |
| ART UNIT | 2196 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers and digital processing systems: Virtual machine task or process management or task management/control 718/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08448391 | Botkin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jonathan Botkin (El Cerrito, California); Simon Graves (Berkeley, California); Matt Danning (Oakland, California); Matthew Culligan (Berkeley, California) |
| ASSIGNEE(S) | SunPower Corporation (San Jose, California) |
| INVENTOR(S) | Jonathan Botkin (El Cerrito, California); Simon Graves (Berkeley, California); Matt Danning (Oakland, California); Matthew Culligan (Berkeley, California) |
| ABSTRACT | A photovoltaic (PV) module assembly including a PV module, a deflector, and a clip. The PV module includes a PV device and a frame. A PV laminate is assembled to the frame, and the frame includes a support arm forming a seat. The deflector defines a front face and a rear face, with the clip extending from either the trailing frame member or the rear face of the deflector. In a mounted state, the deflector is nested within the seat and is releasably mounted to the trailing frame member via the clip. In some embodiments, the support arm forms a second seat, with the PV module assembly providing a second mounted state in which the deflector is in a differing orientation/slope, nested within the second seat and releasably mounted to the trailing frame member via the clip. |
| FILED | Friday, June 29, 2012 |
| APPL NO | 13/538695 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Static structures 052/173.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08448502 | Jesse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen Jesse (Knoxville, Tennessee); Sergei V. Kalinin (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Stephen Jesse (Knoxville, Tennessee); Sergei V. Kalinin (Knoxville, Tennessee) |
| ABSTRACT | Methods and apparatus are described for scanning probe microscopy. A method includes generating a band excitation (BE) signal having finite and predefined amplitude and phase spectrum in at least a first predefined frequency band; exciting a probe using the band excitation signal; obtaining data by measuring a response of the probe in at least a second predefined frequency band; and extracting at least one relevant dynamic parameter of the response of the probe in a predefined range including analyzing the obtained data. The BE signal can be synthesized prior to imaging (static band excitation), or adjusted at each pixel or spectroscopy step to accommodate changes in sample properties (adaptive band excitation). An apparatus includes a band excitation signal generator; a probe coupled to the band excitation signal generator; a detector coupled to the probe; and a relevant dynamic parameter extractor component coupled to the detector, the relevant dynamic parameter extractor including a processor that performs a mathematical transform selected from the group consisting of an integral transform and a discrete transform. |
| FILED | Wednesday, June 02, 2010 |
| APPL NO | 12/792477 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/105 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449592 | Wilson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thomas S. Wilson (San Leandro, California); Duncan J. Maitland (College Station, Texas); Ward Small, IV (Livermore, California); Patrick R. Buckley (San Francisco, California); William J. Benett (Livermore, California); Jonathan Hartman (Sacramento, California); David A. Saloner (San Rafael, California) |
| ASSIGNEE(S) | Regents of the University of California (Oakland, California); The Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Thomas S. Wilson (San Leandro, California); Duncan J. Maitland (College Station, Texas); Ward Small, IV (Livermore, California); Patrick R. Buckley (San Francisco, California); William J. Benett (Livermore, California); Jonathan Hartman (Sacramento, California); David A. Saloner (San Rafael, California) |
| ABSTRACT | A stent for treating a physical anomaly. The stent includes a skeletal support structure for expanding in the physical anomaly and a shape memory material coupled to the skeletal support structure. |
| FILED | Thursday, January 20, 2011 |
| APPL NO | 13/010055 |
| ART UNIT | 3731 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/95 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449650 | Currier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert P. Currier (Santa Fe, New Mexico); Stephen J. Obrey (Los Alamos, New Mexico); David J. Devlin (Santa Fe, New Mexico); Jose Maria Sansinena (Los Alamos, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Robert P. Currier (Santa Fe, New Mexico); Stephen J. Obrey (Los Alamos, New Mexico); David J. Devlin (Santa Fe, New Mexico); Jose Maria Sansinena (Los Alamos, New Mexico) |
| ABSTRACT | Gases are stored, separated, and/or concentrated. An electric field is applied across a porous dielectric adsorbent material. A gas component from a gas mixture may be selectively separated inside the energized dielectric. Gas is stored in the energized dielectric for as long as the dielectric is energized. The energized dielectric selectively separates, or concentrates, a gas component of the gas mixture. When the potential is removed, gas from inside the dielectric is released. |
| FILED | Tuesday, June 15, 2010 |
| APPL NO | 12/816182 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Gas separation: Processes 095/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449674 | Cliber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James A. Cliber (Emmitsburg, Maryland); Roger F. Clark (Knoxville, Maryland); Nathan G. Stoddard (Gettysburg, Pennsylvania); Paul Von Dollen (Frederick, Maryland) |
| ASSIGNEE(S) | AMG Idealcast Solar Corporation (Frederick, Maryland) |
| INVENTOR(S) | James A. Cliber (Emmitsburg, Maryland); Roger F. Clark (Knoxville, Maryland); Nathan G. Stoddard (Gettysburg, Pennsylvania); Paul Von Dollen (Frederick, Maryland) |
| ABSTRACT | This invention relates to a system and a method for liquid silicon containment, such as during the casting of high purity silicon used in solar cells or solar modules. The containment apparatus includes a shielding member adapted to prevent breaching molten silicon from contacting structural elements or cooling elements of a casting device, and a volume adapted to hold a quantity of breaching molten silicon with the volume formed by a bottom and one or more sides. |
| FILED | Wednesday, August 26, 2009 |
| APPL NO | 12/547682 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Single-crystal, oriented-crystal, and epitaxy growth processes; non-coating apparatus therefor 117/73 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449790 | Narula et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chaitanya K. Narula (Knoxville, Tennessee); Claus Daniel (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Chaitanya K. Narula (Knoxville, Tennessee); Claus Daniel (Knoxville, Tennessee) |
| ABSTRACT | A composition comprised of nanoparticles of lithium ion conducting solid oxide material, wherein the solid oxide material is comprised of lithium ions, and at least one type of metal ion selected from pentavalent metal ions and trivalent lanthanide metal ions. Solution methods useful for synthesizing these solid oxide materials, as well as precursor solutions and components thereof, are also described. The solid oxide materials are incorporated as electrolytes into lithium ion batteries. |
| FILED | Monday, June 28, 2010 |
| APPL NO | 12/824350 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compositions 252/182.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08449816 | Seropeghin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yurii D. Seropeghin (Moscow, Russian Federation); Boris L. Zhuikov (Moscow Region, Russian Federation) |
| ASSIGNEE(S) | Brookhaven Science Associates (Upton, New York) |
| INVENTOR(S) | Yurii D. Seropeghin (Moscow, Russian Federation); Boris L. Zhuikov (Moscow Region, Russian Federation) |
| ABSTRACT | A composition suitable for use as a target containing antimony to be irradiated by accelerated charged particles (e.g., by protons to produce tin-117m) comprises an intermetallic compound of antimony and titanium which is synthesized at high-temperature, for example, in an arc furnace. The formed material is powdered and melted in an induction furnace, or heated at high gas pressure in gas static camera. The obtained product has a density, temperature stability, and heat conductivity sufficient to provide an appropriate target material. |
| FILED | Thursday, April 16, 2009 |
| APPL NO | 12/424944 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Powder metallurgy processes 419/33 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450014 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jun Liu (Richland, Washington); Daiwon Choi (Richland, Washington); Zhenguo Yang (Richland, Washington); Donghai Wang (State College, Pennsylvania); Gordon L Graff (West Richland, Washington); Zimin Nie (Richland, Washington); Vilayanur V Viswanathan (Richland, Washington); Jason Zhang (Richland, Washington); Wu Xu (Richland, Washington); Jin Yong Kim (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jun Liu (Richland, Washington); Daiwon Choi (Richland, Washington); Zhenguo Yang (Richland, Washington); Donghai Wang (State College, Pennsylvania); Gordon L Graff (West Richland, Washington); Zimin Nie (Richland, Washington); Vilayanur V Viswanathan (Richland, Washington); Jason Zhang (Richland, Washington); Wu Xu (Richland, Washington); Jin Yong Kim (Richland, Washington) |
| ABSTRACT | Lithium ion batteries having an anode comprising at least one graphene layer in electrical communication with titania to form a nanocomposite material, a cathode comprising a lithium olivine structure, and an electrolyte. The graphene layer has a carbon to oxygen ratio of between 15 to 1 and 500 to 1 and a surface area of between 400 and 2630 m2/g. The nanocomposite material has a specific capacity at least twice that of a titania material without graphene material at a charge/discharge rate greater than about 10 C. The olivine structure of the cathode of the lithium ion battery of the present invention is LiMPO4 where M is selected from the group consisting of Fe, Mn, Co, Ni and combinations thereof. |
| FILED | Saturday, October 09, 2010 |
| APPL NO | 12/901526 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/231.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450111 | Salvo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Roberto Di Salvo (Madison, Alabama); Alton Reich (Huntsville, Alabama); H. Waite H. Dykes, Jr. (Huntsville, Alabama); Rodrigo Teixeira (Huntsville, Alabama) |
| ASSIGNEE(S) | Streamline Automation, LLC (Huntsville, Alabama) |
| INVENTOR(S) | Roberto Di Salvo (Madison, Alabama); Alton Reich (Huntsville, Alabama); H. Waite H. Dykes, Jr. (Huntsville, Alabama); Rodrigo Teixeira (Huntsville, Alabama) |
| ABSTRACT | A one-step process for the lysis of microalgae cell walls and separation of the cellular lipids for use in biofuel production by utilizing a hydrophilic ionic liquid, 1-butyl-3-methylimidazolium. The hydrophilic ionic liquid both lyses the microalgae cell walls and forms two immiscible layers, one of which consists of the lipid contents of the lysed cells. After mixture of the hydrophilic ionic liquid with a suspension of microalgae cells, gravity causes a hydrophobic lipid phase to move to a top phase where it is removed from the mixture and purified. The hydrophilic ionic liquid is recycled to lyse new microalgae suspensions. |
| FILED | Thursday, December 16, 2010 |
| APPL NO | 12/970484 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/390 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450134 | De Ceuster et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Denis De Ceuster (Woodside, California); Peter John Cousins (Menlo Park, California); David D. Smith (Campbell, California) |
| ASSIGNEE(S) | SunPower Corporation (San Jose, California) |
| INVENTOR(S) | Denis De Ceuster (Woodside, California); Peter John Cousins (Menlo Park, California); David D. Smith (Campbell, California) |
| ABSTRACT | A solar cell includes polysilicon P-type and N-type doped regions on a backside of a substrate, such as a silicon wafer. An interrupted trench structure separates the P-type doped region from the N-type doped region in some locations but allows the P-type doped region and the N-type doped region to touch in other locations. Each of the P-type and N-type doped regions may be formed over a thin dielectric layer. Among other advantages, the resulting solar cell structure allows for increased efficiency while having a relatively low reverse breakdown voltage. |
| FILED | Friday, November 12, 2010 |
| APPL NO | 12/945555 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/57 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450246 | Tanatar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Makariy Tanatar (Ames, Iowa); Ruslan Prozorov (Ames, Iowa); Ni Ni (Ames, Iowa); Sergey Bud'ko (Ames, Iowa); Paul Canfield (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Amos, Iowa) |
| INVENTOR(S) | Makariy Tanatar (Ames, Iowa); Ruslan Prozorov (Ames, Iowa); Ni Ni (Ames, Iowa); Sergey Bud'ko (Ames, Iowa); Paul Canfield (Ames, Iowa) |
| ABSTRACT | Method of making a low resistivity electrical connection between an electrical conductor and an iron pnictide superconductor involves connecting the electrical conductor and superconductor using a tin or tin-based material therebetween, such as using a tin or tin-based solder. The superconductor can be based on doped AFe2As2, where A can be Ca, Sr, Ba, Eu or combinations thereof for purposes of illustration only. |
| FILED | Tuesday, February 15, 2011 |
| APPL NO | 12/931999 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Superconductor technology: Apparatus, material, process 55/100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450404 | Bowen, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel E. Bowen, III (Olathe, Kansas); Eric A. Eastwood (Raymore, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Daniel E. Bowen, III (Olathe, Kansas); Eric A. Eastwood (Raymore, Missouri) |
| ABSTRACT | Compositions comprising a polymer-containing matrix and a filler comprising a cage compound selected from borane cage compounds, carborane cage compounds, metal complexes thereof, residues thereof, mixtures thereof, and/or agglomerations thereof, where the cage compound is not covalently bound to the matrix polymer. Methods of making and applications for using such compositions are also disclosed. |
| FILED | Wednesday, June 16, 2010 |
| APPL NO | 12/816555 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 524/185 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450540 | Roes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Augustinus Wilhelmus Maria Roes (Houston, Texas); Vijay Nair (Katy, Texas); Erwin Hunh Munsterman (Amsterdam, Netherlands); Petrus Franciscus Van Bergen (Amsterdam, Netherlands); Franciscus Gondulfus Antonius Van Den Berg (Amsterdam, Netherlands) |
| ASSIGNEE(S) | Shell Oil Company (Houston, Texas) |
| INVENTOR(S) | Augustinus Wilhelmus Maria Roes (Houston, Texas); Vijay Nair (Katy, Texas); Erwin Hunh Munsterman (Amsterdam, Netherlands); Petrus Franciscus Van Bergen (Amsterdam, Netherlands); Franciscus Gondulfus Antonius Van Den Berg (Amsterdam, Netherlands) |
| ABSTRACT | Methods for treating a subsurface formation and compositions produced therefrom are described herein. At least one method for producing hydrocarbons from a subsurface formation includes providing heat to the subsurface formation using an in situ heat treatment process. One or more formation particles may be formed during heating of the subsurface formation. Fluid that includes hydrocarbons and the formation particles may be produced from the subsurface formation. The formation particles in the produced fluid may include cenospheres and have an average particle size of at least 0.5 micrometers. |
| FILED | Wednesday, September 02, 2009 |
| APPL NO | 12/552955 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry of hydrocarbon compounds 585/13 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450629 | Pitcher |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eric John Pitcher (Santa Fe, New Mexico) |
| ASSIGNEE(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Eric John Pitcher (Santa Fe, New Mexico) |
| ABSTRACT | Method of producing molybdenum-99, comprising accelerating ions by means of an accelerator; directing the ions onto a metal target so as to generate neutrons having an energy of greater than 10 MeV; directing the neutrons through a converter material comprising techentium-99 to produce a mixture comprising molybdenum-99; and, chemically extracting the molybdenum-99 from the mixture. |
| FILED | Tuesday, May 10, 2011 |
| APPL NO | 13/104698 |
| ART UNIT | 1756 — Electrical Circuits and Systems |
| CURRENT CPC | Chemistry: Electrical and wave energy 24/157.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450644 | Tang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jason C. H. Tang (Sterling Heights, Michigan); Wayne W. Cai (Troy, Michigan) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Jason C. H. Tang (Sterling Heights, Michigan); Wayne W. Cai (Troy, Michigan) |
| ABSTRACT | A system and method for providing multi-mode control of an ultrasonic welding system. In one embodiment, the control modes include the energy of the weld, the time of the welding process and the compression displacement of the parts being welded during the welding process. The method includes providing thresholds for each of the modes, and terminating the welding process after the threshold for each mode has been reached, the threshold for more than one mode has been reached or the threshold for one of the modes has been reached. The welding control can be either open-loop or closed-loop, where the open-loop process provides the mode thresholds and once one or more of those thresholds is reached the welding process is terminated. The closed-loop control provides feedback of the weld energy and/or the compression displacement so that the weld power and/or weld pressure can be increased or decreased accordingly. |
| FILED | Thursday, March 03, 2011 |
| APPL NO | 13/039979 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Electric heating 219/124.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450704 | Buonassisi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anthony Buonassisi (Cambridge, Massachusetts); Mariana Bertoni (Medford, Massachusetts); Bonna Newman (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Anthony Buonassisi (Cambridge, Massachusetts); Mariana Bertoni (Medford, Massachusetts); Bonna Newman (Cambridge, Massachusetts) |
| ABSTRACT | A system for modifying dislocation distributions in semiconductor materials is provided. The system includes one or more vibrational sources for producing at least one excitation of vibrational mode having phonon frequencies so as to enhance dislocation motion through a crystal lattice. |
| FILED | Friday, December 03, 2010 |
| APPL NO | 12/959795 |
| ART UNIT | 2823 — Optics |
| CURRENT CPC | Radiant energy 250/492.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450707 | Brindza et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul Daniel Brindza (Yorktown, Virginia); Bert Clayton Metzger (Seaford, Virginia) |
| ASSIGNEE(S) | Jefferson Science Associates, LLC (Newport News, Virginia) |
| INVENTOR(S) | Paul Daniel Brindza (Yorktown, Virginia); Bert Clayton Metzger (Seaford, Virginia) |
| ABSTRACT | A thermal neutron shield comprising concrete with a high percentage of the element Boron. The concrete is least 54% Boron by weight which maximizes the effectiveness of the shielding against thermal neutrons. The accompanying method discloses the manufacture of Boron loaded concrete which includes enriching the concrete mixture with varying grit sizes of Boron Carbide. |
| FILED | Tuesday, March 22, 2011 |
| APPL NO | 13/065437 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/518.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450730 | Forrest |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen R. Forrest (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan) |
| ABSTRACT | Light emitting devices are provided that include one or more OLEDs disposed only on a peripheral region of the substrate. An OLED may be disposed only on a peripheral region of a substantially transparent substrate and configured to emit light into the substrate. Another surface of the substrate may be roughened or include other features to outcouple light from the substrate. The edges of the substrate may be beveled and/or reflective. The area of the OLED(s) may be relatively small compared to the substrate surface area through which light is emitted from the device. One or more OLEDs also or alternatively may be disposed on an edge of the substrate about perpendicular to the surface of the substrate through which light is emitted, such that they emit light into the substrate. A mode expanding region may be included between each such OLED and the substrate. |
| FILED | Wednesday, February 02, 2011 |
| APPL NO | 13/019753 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450773 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jin K. Kim (Albuquerque, New Mexico); Samuel D. Hawkins (Albuquerque, New Mexico); John F. Klem (Albuquerque, New Mexico); Michael J. Cich (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Jin K. Kim (Albuquerque, New Mexico); Samuel D. Hawkins (Albuquerque, New Mexico); John F. Klem (Albuquerque, New Mexico); Michael J. Cich (Albuquerque, New Mexico) |
| ABSTRACT | A photodetector is disclosed for the detection of infrared light with a long cutoff wavelength in the range of about 4.5-10 microns. The photodetector, which can be formed on a semiconductor substrate as an nBn device, has a light absorbing region which includes InAsSb light-absorbing layers and tensile-strained layers interspersed between the InAsSb light-absorbing layers. The tensile-strained layers can be formed from GaAs, InAs, InGaAs or a combination of these III-V compound semiconductor materials. A barrier layer in the photodetector can be formed from AlAsSb or AlGaAsSb; and a contact layer in the photodetector can be formed from InAs, GaSb or InAsSb. The photodetector is useful as an individual device, or to form a focal plane array. |
| FILED | Thursday, July 15, 2010 |
| APPL NO | 12/836769 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/184 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451164 | Dowla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Farid Dowla (Castro Valley, California); Faranak Nekoogar (San Ramon, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC. (Livermore, California) |
| INVENTOR(S) | Farid Dowla (Castro Valley, California); Faranak Nekoogar (San Ramon, California) |
| ABSTRACT | In one embodiment, a radar communication system includes a plurality of radars having a communication range and being capable of operating at a sensing frequency and a reporting frequency, wherein the reporting frequency is different than the sensing frequency, each radar is adapted for operating at the sensing frequency until an event is detected, each radar in the plurality of radars has an identification/location frequency for reporting information different from the sensing frequency, a first radar of the radars which senses the event sends a reporting frequency corresponding to its identification/location frequency when the event is detected, and all other radars in the plurality of radars switch their reporting frequencies to match the reporting frequency of the first radar upon detecting the reporting frequency switch of a radar within the communication range. In another embodiment, a method is presented for communicating information in a radar system. |
| FILED | Wednesday, February 09, 2011 |
| APPL NO | 13/024105 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/59 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451444 | Parks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James E. Parks (Knoxville, Tennessee); William P. Partridge (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | James E. Parks (Knoxville, Tennessee); William P. Partridge (Oak Ridge, Tennessee) |
| ABSTRACT | A system for sensing particulate in a combustion gas stream is disclosed. The system transmits light into a combustion gas stream, and thereafter detects a portion of the transmitted light as scattered light in an amount corresponding to the amount of particulates in the emissions. Purge gas may be supplied adjacent the light supply and the detector to reduce particles in the emissions from coating or otherwise compromising the transmission of light into the emissions and recovery of scattered light from the emissions. |
| FILED | Thursday, June 25, 2009 |
| APPL NO | 12/491781 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/53 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451877 | Crawford et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mary Crawford (Albuquerque, New Mexico); Daniel Koleske (Albuquerque, New Mexico); Jaehee Cho (Troy, New York); Di Zhu (Troy, New York); Ahmed Noemaun (Troy, New York); Martin F. Schubert (Boise, Idaho); E. Fred Schubert (Troy, New York) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Mary Crawford (Albuquerque, New Mexico); Daniel Koleske (Albuquerque, New Mexico); Jaehee Cho (Troy, New York); Di Zhu (Troy, New York); Ahmed Noemaun (Troy, New York); Martin F. Schubert (Boise, Idaho); E. Fred Schubert (Troy, New York) |
| ABSTRACT | Tailored doping of barrier layers enables balancing of the radiative recombination among the multiple-quantum-wells in III-Nitride light-emitting diodes. This tailored doping enables more symmetric carrier transport and uniform carrier distribution which help to reduce electron leakage and thus reduce the efficiency droop in high-power III-Nitride LEDs. Mitigation of the efficiency droop in III-Nitride LEDs may enable the pervasive market penetration of solid-state-lighting technologies in high-power lighting and illumination. |
| FILED | Thursday, March 17, 2011 |
| APPL NO | 13/050673 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/2018 (20130101) H01S 5/3413 (20130101) Original (OR) Class H01S 5/18308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452134 | Davids et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Paul Davids (Albuquerque, New Mexico); David W. Peters (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Paul Davids (Albuquerque, New Mexico); David W. Peters (Albuquerque, New Mexico) |
| ABSTRACT | A frequency selective infrared (IR) photodetector having a predetermined frequency band. The exemplary frequency selective photodetector includes: a dielectric IR absorber having a first surface and a second surface substantially parallel to the first surface; an electrode electrically coupled to the first surface of the dielectric IR absorber; and a frequency selective surface plasmonic (FSSP) structure formed on the second surface of the dielectric IR absorber. The FSSP structure is designed to selectively transmit radiation in the predetermined frequency band that is incident on the FSSP structure substantially independent of the angle of incidence of the incident radiation on the FSSP structure. |
| FILED | Monday, August 30, 2010 |
| APPL NO | 12/871334 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/12 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452538 | Klein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James D. Klein (Tucson, Arizona); David A. Schoderbek (Eagle River, Alaska); Jason M. Mailloux (Laramie, Wyoming) |
| ASSIGNEE(S) | ConocoPhillips Company (Houston, Texas) |
| INVENTOR(S) | James D. Klein (Tucson, Arizona); David A. Schoderbek (Eagle River, Alaska); Jason M. Mailloux (Laramie, Wyoming) |
| ABSTRACT | Methods and systems are provided for evaluating petrophysical properties of subterranean formations and comprehensively evaluating hydrate presence through a combination of computer-implemented log modeling and analysis. Certain embodiments include the steps of running a number of logging tools in a wellbore to obtain a variety of wellbore data and logs, and evaluating and modeling the log data to ascertain various petrophysical properties. Examples of suitable logging techniques that may be used in combination with the present invention include, but are not limited to, sonic logs, electrical resistivity logs, gamma ray logs, neutron porosity logs, density logs, NRM logs, or any combination or subset thereof. |
| FILED | Monday, August 23, 2010 |
| APPL NO | 12/861485 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/7 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452542 | Zemla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Adam T. Zemla (Brentwood, California); Carol E. Zhou (Pleasanton, California); Marisa W. Lam (Pleasanton, California); Jason R. Smith (Mountain House, California); Elizabeth Pardes (Pleasanton, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC. (Livermore, California) |
| INVENTOR(S) | Adam T. Zemla (Brentwood, California); Carol E. Zhou (Pleasanton, California); Marisa W. Lam (Pleasanton, California); Jason R. Smith (Mountain House, California); Elizabeth Pardes (Pleasanton, California) |
| ABSTRACT | Disclosed are computational methods, and associated hardware and software products for scoring conservation in a protein structure based on a computationally identified family or cluster of protein structures. A method of computationally identifying a family or cluster of protein structures in also disclosed herein. |
| FILED | Tuesday, August 07, 2007 |
| APPL NO | 11/890864 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452767 | Turner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alan E. Turner (Richland, Washington); Elizabeth G. Hetzler (Richland, Washington); Grant C. Nakamura (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Alan E. Turner (Richland, Washington); Elizabeth G. Hetzler (Richland, Washington); Grant C. Nakamura (Richland, Washington) |
| ABSTRACT | Text analysis devices, articles of manufacture, and text analysis methods are described according to some aspects. In one aspect, a text analysis device includes processing circuitry configured to analyze initial text to generate a measurement basis usable in analysis of subsequent text, wherein the measurement basis comprises a plurality of measurement features from the initial text, a plurality of dimension anchors from the initial text and a plurality of associations of the measurement features with the dimension anchors, and wherein the processing circuitry is configured to access a viewpoint indicative of a perspective of interest of a user with respect to the analysis of the subsequent text, and wherein the processing circuitry is configured to use the viewpoint to generate the measurement basis. |
| FILED | Friday, September 15, 2006 |
| APPL NO | 11/522178 |
| ART UNIT | 2167 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/736 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 08448433 | McBride et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Troy O. McBride (Norwich, Vermont); Benjamin R. Bollinger (Windsor, Vermont); Michael Schaefer (Port Orchard, Washington); Dax Kepshire (Enfield, New Hampshire) |
| ASSIGNEE(S) | SustainX, Inc. (Seabrook, New Hampshire) |
| INVENTOR(S) | Troy O. McBride (Norwich, Vermont); Benjamin R. Bollinger (Windsor, Vermont); Michael Schaefer (Port Orchard, Washington); Dax Kepshire (Enfield, New Hampshire) |
| ABSTRACT | In various embodiments, energy-storage systems are based upon an open-air arrangement in which pressurized gas is expanded in small batches from a high pressure of, e.g., several hundred atmospheres to atmospheric pressure. The systems may be sized and operated at a rate that allows for near isothermal expansion and compression of the gas. |
| FILED | Tuesday, June 07, 2011 |
| APPL NO | 13/154996 |
| ART UNIT | 3748 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Power plants 060/508 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08448514 | Hartmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mitra J. Hartmann (Evanston, Illinois); Joseph H. Solomon (River Forest, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Mitra J. Hartmann (Evanston, Illinois); Joseph H. Solomon (River Forest, Illinois) |
| ABSTRACT | A sensing device includes an elongated whisker element having a flexible cantilever region and a base region where a change in moment or curvature is generated by bending of the cantilever region when it contacts an object. One or more sensor elements cooperatively associated with the whisker element provide one or more output signals that is/are representative of two orthogonal components of change in moment or curvature at the whisker base region to permit determination of object distance, fluid velocity profile, or object contour (shape) with accounting for lateral slip of the whisker element and frictional characteristics of the object. Multiple sensing devices can be arranged in arrays in a manner to sense object contour without or with adjustment for lateral slip. |
| FILED | Tuesday, July 06, 2010 |
| APPL NO | 12/803761 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/521 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450471 | Voytas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel F. Voytas (Falcon Heights, Minnesota); Adam J. Bogdanove (Ames, Iowa); Feng Zhang (Plymouth, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Saint Paul, Minnesota); Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Daniel F. Voytas (Falcon Heights, Minnesota); Adam J. Bogdanove (Ames, Iowa); Feng Zhang (Plymouth, Minnesota) |
| ABSTRACT | Materials and Methods related to gene targeting (e.g., gene targeting with transcription activator-like effector nucleases; “TALENS”) are provided. |
| FILED | Thursday, March 22, 2012 |
| APPL NO | 13/426991 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/23.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450690 | Averitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Richard Averitt (Newton, Massachusetts); Xin Zhang (Medford, Massachusetts); Hu Tao (Medford, Massachusetts); Andrew Strikwerda (Jamaica Plain, Massachusetts); Willie J. Padilla (Newton, Massachusetts); Eric Shaner (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts); Trustees of Boston College (Chestnut Hill, Massachusetts) |
| INVENTOR(S) | Richard Averitt (Newton, Massachusetts); Xin Zhang (Medford, Massachusetts); Hu Tao (Medford, Massachusetts); Andrew Strikwerda (Jamaica Plain, Massachusetts); Willie J. Padilla (Newton, Massachusetts); Eric Shaner (Albuquerque, New Mexico) |
| ABSTRACT | An apparatus and method are disclosed for detecting terahertz radiation at room temperature. A detecting pixel includes a sub-wavelength split-ring resonator, and is mechanically coupled to (but thermally decoupled from) a substrate via a cantilever formed from two materials that have a significant mismatch in their thermal expansion coefficients. Incident radiation causes the split-ring resonator to resonate, thereby generating heat that is transferred to the cantilever, causing the cantilever to flex. An optical readout system includes a secondary light source, such as a laser, that shines on a reflective surface on the pixel, whereby a photodiode detects the reflected light and permits calculation of a relative deflection of the pixel in the nanometer range. An exemplary detector has a noise equivalent power rating of approximately 60 pW/√Hz. |
| FILED | Tuesday, October 04, 2011 |
| APPL NO | 13/252821 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Radiant energy 250/341.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08451004 — Multicoil low-field nuclear magnetic resonance detection and imaging apparatus and method
| US 08451004 | Walsh |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David O. Walsh (Mukilteo, Washington) |
| ASSIGNEE(S) | Vista Clara Inc. (Mukilteo, Washington) |
| INVENTOR(S) | David O. Walsh (Mukilteo, Washington) |
| ABSTRACT | A multicoil NMR detection and imaging apparatus allows multicoil NMR detection and imaging to be performed efficiently at low operating frequencies. The apparatus comprises an AC voltage generator, a transmit switching circuit, a coil switching network, an array of two or more detection coils, a set of receive switching circuits with one switching circuit for each detection coil, and a set of preamplifier circuits with input impedance substantially greater than the impedance of each respective detection coil at the intended operating frequency. The AC generator produces an alternating current waveform that is routed through one of more detection coils during transmit mode while the preamplifier circuits are isolated from the detection coil(s). During receive mode the AC generator is isolated from the detection coils to prevent noise from the transmitter from degrading the quality of received signals. |
| FILED | Wednesday, April 20, 2011 |
| APPL NO | 13/090436 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/309 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451124 | Lynch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jerome P. Lynch (Ann Arbor, Michigan); Nicholas A. Kotov (Ypsilanti, Michigan); Kenneth J. Loh (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of The University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Jerome P. Lynch (Ann Arbor, Michigan); Nicholas A. Kotov (Ypsilanti, Michigan); Kenneth J. Loh (Ann Arbor, Michigan) |
| ABSTRACT | A method for sensing a stimulus comprising providing a sensing assembly having a first structure and a second structure, wherein the first structure is made of a material different than the second structure and each of the first structure and the second structure is nanoscale. The method further includes providing an inductive antenna operably coupled to the sensing assembly, disposing the sensing assembly upon a spatial area, exposing the sensing assembly to the stimulus thereby producing a detectable change in the sensing assembly, and wirelessly coupling a reader with the inductive antenna to obtain a signal representative of the detectable change in the sensing assembly. |
| FILED | Friday, September 12, 2008 |
| APPL NO | 12/209330 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Communications: Electrical 340/572.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451190 | Makarov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sergey N. Makarov (Holden, Massachusetts); Francesca Scire-Scappuzzo (Lexington, Massachusetts) |
| ASSIGNEE(S) | Physical Sciences, Inc. (Andover, Massachusetts) |
| INVENTOR(S) | Sergey N. Makarov (Holden, Massachusetts); Francesca Scire-Scappuzzo (Lexington, Massachusetts) |
| ABSTRACT | Described is an apparatus and method for reducing noise in an information bearing signal is provided. A feeding element receives dual-polarized wideband electromagnetic signals. The feeding element is coupled to a Non-Cutoff Frequency Selective Surface ground plane. The Non-Cutoff Frequency Selective Surface ground plane allows for a line-of-sight signal and a surface wave to cancel. The Non-Cutoff Frequency Selective Surface ground plane can be a metal plate with a plurality of corrugations. The corrugations can be concentric rings, each corrugation having a predetermined height and a predetermined spacing from adjacent corrugations. |
| FILED | Wednesday, July 13, 2011 |
| APPL NO | 13/182263 |
| ART UNIT | 2821 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Radio wave antennas 343/909 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451338 | Levin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anat Levin (Brookline, Massachusetts); Peter Sand (Brooklyn, New York); Taeg Sang Cho (Cambridge, Massachusetts); Fredo Durand (Boston, Massachusetts); William T. Freeman (Acton, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Anat Levin (Brookline, Massachusetts); Peter Sand (Brooklyn, New York); Taeg Sang Cho (Cambridge, Massachusetts); Fredo Durand (Boston, Massachusetts); William T. Freeman (Acton, Massachusetts) |
| ABSTRACT | Object motion during camera exposure often leads to noticeable blurring artifacts. Proper elimination of this blur is challenging because the blur kernel is unknown, varies over the image as a function of object velocity, and destroys high frequencies. In the case of motions along a 1D direction (e.g. horizontal), applicants show that these challenges can be addressed using a camera that moves during the exposure. Through the analysis of motion blur as space-time integration, applicants show that a parabolic integration (corresponding to constant sensor acceleration) leads to motion blur that is not only invariant to object velocity, but preserves image frequency content nearly optimally. That is, static objects are degraded relative to their image from a static camera, but all moving objects within a given range of motions reconstruct well. A single deconvolution kernel can be used to remove blur and create sharp images of scenes with objects moving at different speeds, without requiring any segmentation and without knowledge of the object speeds. |
| FILED | Friday, March 28, 2008 |
| APPL NO | 12/058105 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Television 348/208.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451442 | Benderskii et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander V. Benderskii (La Canada Flintridge, California); Igor V. Stiopkin (Madison, Wisconsin); Himali Dilrukshi Jayathilake (South Hadley, Massachusetts) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Alexander V. Benderskii (La Canada Flintridge, California); Igor V. Stiopkin (Madison, Wisconsin); Himali Dilrukshi Jayathilake (South Hadley, Massachusetts) |
| ABSTRACT | Method and apparatus for performing spectroscopy, include the combining of first and second light beams to form a reference beam, focusing the first and second light beams and the reference beam onto a sample, receiving a reflected light beam from the sample at a monochromator, and viewing a predetermined wavelength band of the reflected light beam from the monochromator. Portions of the first and second light beams, which may be visible and IR forms of electromagnetic energy, are heterodyned through a crystal. A monochromator receives a reflection of the reference beam from the sample, and Fourier transformation is performed on the output of the monochromator. The first and second beams of electromagnetic energy can be split to form first and second component beams and the reference beam, all of which are propagated to the sample. |
| FILED | Wednesday, June 18, 2008 |
| APPL NO | 12/452192 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/326 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451756 | Lucani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel E. Lucani (Oporto, Portugal); Milica Stojanovic (Boston, Massachusetts); Muriel Medard (Belmont, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel E. Lucani (Oporto, Portugal); Milica Stojanovic (Boston, Massachusetts); Muriel Medard (Belmont, Massachusetts) |
| ABSTRACT | Subject matter disclosed herein relates to random linear network coding schemes for reliable communications for time division duplexing channels. In at least one embodiment, a transmitter node transmits M data packets through a half-duplex link using random linear network coding. The transmitter node transmits coded packets back-to-back through the link before stopping to wait for an acknowledgement (ACK) packet. An optimal number of coded packets Ni to be transmitted in a subsequent transmission may then be determined based, at least in part, on a number of degrees of freedom (DOFs) a receiving node needs to decode the M information packets from received coded packets. |
| FILED | Tuesday, May 15, 2012 |
| APPL NO | 13/471496 |
| ART UNIT | 2474 — Multiplex and VoIP |
| CURRENT CPC | Multiplex communications 370/276 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452049 | Rubenstein |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eric P. Rubenstein (East Hartford, Connecticut) |
| ASSIGNEE(S) | Advanced Fuel Research, Inc. (East Hartford, Connecticut) |
| INVENTOR(S) | Eric P. Rubenstein (East Hartford, Connecticut) |
| ABSTRACT | The invention described herein is generally directed to methods for analyzing an image. In particular, crowded field images may be analyzed for unidentified, unobserved objects based on an iterative analysis of modified images including artificial objects or removed real objects. The results can provide an estimate of the completeness of analysis of the image, an estimate of the number of objects that are unobserved in the image, and an assessment of the quality of other similar images. |
| FILED | Monday, March 19, 2012 |
| APPL NO | 13/423803 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452123 | Leprince et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sebastien Leprince (Pasadena, California); Pablo Muse' (Montevideo, Uruguay); Jean-Philippe Avouau (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Sebastien Leprince (Pasadena, California); Pablo Muse' (Montevideo, Uruguay); Jean-Philippe Avouau (Pasadena, California) |
| ABSTRACT | A method for calibrating an imaging instrument, possibly located on an aircraft or satellite, is described. According to the method, an image acquired by the instrument is ortho-rectified, and then co-registered and correlated with a reference image. In this way, ground disparities between the acquired image and the reference image are measured. Updated instrument pointing directions that correct for the disparities measured are then determined and adopted as corrective calibrations for the distortions of the instrument. |
| FILED | Saturday, December 20, 2008 |
| APPL NO | 12/340696 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Image analysis 382/276 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452749 | Corella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Francisco Corella (San Diego, California); Karen Pomian Lewison (San Diego, California) |
| ASSIGNEE(S) | Pomian and Corella, LLC (San Jose, California) |
| INVENTOR(S) | Francisco Corella (San Diego, California); Karen Pomian Lewison (San Diego, California) |
| ABSTRACT | A method for visiting a results page of a time-varying result set of a search query. The method includes displaying to a user a list of results belonging to the visited page, each result comprising a hyperlink to a document, a result being de-emphasized if the URL used in its hyperlink is present in a set of URLs of results that are deemed to have been seen by the user. When the user clicks or taps a page menu button to navigate to a different page, the method further includes adding to that set the URLs of the results of the visited page. Page menu buttons are highlighted if they pertain to pages containing results deemed to have been seen by the user. |
| FILED | Monday, April 02, 2012 |
| APPL NO | 13/437927 |
| ART UNIT | 2161 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/706 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08448498 | Kelley |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anthony R. Kelley (Somerville, Alabama) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Anthony R. Kelley (Somerville, Alabama) |
| ABSTRACT | The present invention is a hermetic seal leak detection apparatus, which can be used to test for hermetic seal leaks in instruments and containers. A vacuum tight chamber is created around the unit being tested to minimize gas space outside of the hermetic seal. A vacuum inducing device is then used to increase the gas chamber volume inside the device, so that a slight vacuum is pulled on the unit being tested. The pressure in the unit being tested will stabilize. If the stabilized pressure reads close to a known good seal calibration, there is not a leak in the seal. If the stabilized pressure reads closer to a known bad seal calibration value, there is a leak in the seal. The speed of the plunger can be varied and by evaluating the resulting pressure change rates and final values, the leak rate/size can be accurately calculated. |
| FILED | Friday, August 27, 2010 |
| APPL NO | 12/870468 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/49.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08448514 | Hartmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mitra J. Hartmann (Evanston, Illinois); Joseph H. Solomon (River Forest, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Mitra J. Hartmann (Evanston, Illinois); Joseph H. Solomon (River Forest, Illinois) |
| ABSTRACT | A sensing device includes an elongated whisker element having a flexible cantilever region and a base region where a change in moment or curvature is generated by bending of the cantilever region when it contacts an object. One or more sensor elements cooperatively associated with the whisker element provide one or more output signals that is/are representative of two orthogonal components of change in moment or curvature at the whisker base region to permit determination of object distance, fluid velocity profile, or object contour (shape) with accounting for lateral slip of the whisker element and frictional characteristics of the object. Multiple sensing devices can be arranged in arrays in a manner to sense object contour without or with adjustment for lateral slip. |
| FILED | Tuesday, July 06, 2010 |
| APPL NO | 12/803761 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/521 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450498 | Paley |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark S. Paley (Huntsville, Alabama) |
| ASSIGNEE(S) | AZ Technology, Inc. (Huntsville, Alabama) |
| INVENTOR(S) | Mark S. Paley (Huntsville, Alabama) |
| ABSTRACT | Ionic liquid epoxide monomers capable of reacting with cross-linking agents to form polymers with high tensile and adhesive strengths. Ionic liquid epoxide monomers comprising at least one bis(glycidyl) N-substituted nitrogen heterocyclic cation are made from nitrogen heterocycles corresponding to the bis(glycidyl) N-substituted nitrogen heterocyclic cations by a method involving a non-nucleophilic anion, an alkali metal cation, epichlorohydrin, and a strong base. |
| FILED | Saturday, May 14, 2011 |
| APPL NO | 13/107904 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Organic compounds 548/304.700 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450536 | White et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emily Bostwick White (Wheat Ridge, Colorado); Cherie Wilson (Lakewood, Colorado); Mark Berggren (Golden, Colorado); Robert M. Zubrin (Indian Hills, Colorado) |
| ASSIGNEE(S) | Pioneer Energy, Inc. (Lakewood, Colorado) |
| INVENTOR(S) | Emily Bostwick White (Wheat Ridge, Colorado); Cherie Wilson (Lakewood, Colorado); Mark Berggren (Golden, Colorado); Robert M. Zubrin (Indian Hills, Colorado) |
| ABSTRACT | Systems, catalysts, and methods are provided for transforming carbon based material into synthetic mixed alcohol fuel. |
| FILED | Friday, July 17, 2009 |
| APPL NO | 12/504913 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/34 (20130101) B01J 23/72 (20130101) Acyclic or Carbocyclic Compounds C07C 29/34 (20130101) Original (OR) Class C07C 2523/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452073 | Taminger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Karen M. Taminger (Yorktown, Virginia); Robert A. Hafley (Yorktown, Virginia); Richard E. Martin (Yorktown, Virginia); William H. Hofmeister (Nashville, Tennessee) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Karen M. Taminger (Yorktown, Virginia); Robert A. Hafley (Yorktown, Virginia); Richard E. Martin (Yorktown, Virginia); William H. Hofmeister (Nashville, Tennessee) |
| ABSTRACT | A closed-loop control method for an electron beam freeform fabrication (EBF3) process includes detecting a feature of interest during the process using a sensor(s), continuously evaluating the feature of interest to determine, in real time, a change occurring therein, and automatically modifying control parameters to control the EBF3 process. An apparatus provides closed-loop control method of the process, and includes an electron gun for generating an electron beam, a wire feeder for feeding a wire toward a substrate, wherein the wire is melted and progressively deposited in layers onto the substrate, a sensor(s), and a host machine. The sensor(s) measure the feature of interest during the process, and the host machine continuously evaluates the feature of interest to determine, in real time, a change occurring therein. The host machine automatically modifies control parameters to the EBF3 apparatus to control the EBF3 process in a closed-loop manner. |
| FILED | Wednesday, March 31, 2010 |
| APPL NO | 12/750991 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Image analysis 382/141 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08453160 | Sunderland et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dean E. Sunderland (Glendale, Arizona); Terry J. Ahrendt (Mesa, Arizona); Tim Moore (Phoenix, Arizona) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Dean E. Sunderland (Glendale, Arizona); Terry J. Ahrendt (Mesa, Arizona); Tim Moore (Phoenix, Arizona) |
| ABSTRACT | Methods and systems are provided for authorizing a command of an integrated modular environment in which a plurality of partitions control actions of a plurality of effectors is provided. A first identifier, a second identifier, and a third identifier are determined. The first identifier identifies a first partition of the plurality of partitions from which the command originated. The second identifier identifies a first effector of the plurality of effectors for which the command is intended. The third identifier identifies a second partition of the plurality of partitions that is responsible for controlling the first effector. The first identifier and the third identifier are compared to determine whether the first partition is the same as the second partition for authorization of the command. |
| FILED | Thursday, March 11, 2010 |
| APPL NO | 12/721932 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electrical computers and digital processing systems: Interprogram communication or interprocess communication 719/312 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08449880 | Dolnik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vladislav Dolnik (Palo Alto, California); William A. Gurske (Fremont, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vladislav Dolnik (Palo Alto, California); William A. Gurske (Fremont, California) |
| ABSTRACT | Disclosed herein is a composition and method for sample preparation of proteins for their size separation by electrophoresis, suitable for molecular-weight determination of proteins in the range between about 14,000 and 500,000. In an embodiment, proteins, particularly those exhibiting biased migration, are modified to change their intrinsic charge, or carbohydrate component to improve accuracy of their molecular weights as determined by electrophoretic size separation via their interaction with ionic surfactants. In a preferred embodiment, the proteins are carbamylated with potassium cyanate and their carbohydrate components are oxidized with sodium periodate. |
| FILED | Monday, November 22, 2010 |
| APPL NO | 12/952166 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/94.300 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450285 | McCoy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sharon L. McCoy (Portland, Oregon); Steven H. Hefeneider (Portland, Oregon) |
| ASSIGNEE(S) | 13Therapeutics, Inc. (Portland, Oregon) |
| INVENTOR(S) | Sharon L. McCoy (Portland, Oregon); Steven H. Hefeneider (Portland, Oregon) |
| ABSTRACT | Peptides for the treatment of inflammation, and therapeutic uses and methods of using the same are disclosed. Peptides including a transducing sequence are effective for inhibiting cytokine activity and TNF-α secretion through interaction with toll-like receptors. Experiments are described illustrating the efficacy of the compounds in treating otitis media. |
| FILED | Friday, June 04, 2010 |
| APPL NO | 12/794185 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/21.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450730 | Forrest |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stephen R. Forrest (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Stephen R. Forrest (Ann Arbor, Michigan) |
| ABSTRACT | Light emitting devices are provided that include one or more OLEDs disposed only on a peripheral region of the substrate. An OLED may be disposed only on a peripheral region of a substantially transparent substrate and configured to emit light into the substrate. Another surface of the substrate may be roughened or include other features to outcouple light from the substrate. The edges of the substrate may be beveled and/or reflective. The area of the OLED(s) may be relatively small compared to the substrate surface area through which light is emitted from the device. One or more OLEDs also or alternatively may be disposed on an edge of the substrate about perpendicular to the surface of the substrate through which light is emitted, such that they emit light into the substrate. A mode expanding region may be included between each such OLED and the substrate. |
| FILED | Wednesday, February 02, 2011 |
| APPL NO | 13/019753 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451189 | Fluhler |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Herbert U. Fluhler (Madison, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Herbert U. Fluhler (Madison, Alabama) |
| ABSTRACT | This disclosure demonstrates a new class of Ultra-Wide Band (UWB) AMC with very large fractional bandwidth (>100%) even at lower frequencies (<1 GHz). This new UWB AMC is enabled by recognizing that any AMC must be an antenna in order to accept the incident radiation into the circuit. Therefore, by using UWB antenna design features, one can make wide band AMCs. Additionally, by manipulation of the UWB AMC element design, a 1/frequency dependence can be obtained for instantiating the benefits of a quarter wave reflection over a large UWB bandwidth with a single physical thickness. |
| FILED | Thursday, April 15, 2010 |
| APPL NO | 12/761278 |
| ART UNIT | 2821 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Radio wave antennas 343/909 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452049 | Rubenstein |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Eric P. Rubenstein (East Hartford, Connecticut) |
| ASSIGNEE(S) | Advanced Fuel Research, Inc. (East Hartford, Connecticut) |
| INVENTOR(S) | Eric P. Rubenstein (East Hartford, Connecticut) |
| ABSTRACT | The invention described herein is generally directed to methods for analyzing an image. In particular, crowded field images may be analyzed for unidentified, unobserved objects based on an iterative analysis of modified images including artificial objects or removed real objects. The results can provide an estimate of the completeness of analysis of the image, an estimate of the number of objects that are unobserved in the image, and an assessment of the quality of other similar images. |
| FILED | Monday, March 19, 2012 |
| APPL NO | 13/423803 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image analysis 382/103 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08452749 | Corella et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Francisco Corella (San Diego, California); Karen Pomian Lewison (San Diego, California) |
| ASSIGNEE(S) | Pomian and Corella, LLC (San Jose, California) |
| INVENTOR(S) | Francisco Corella (San Diego, California); Karen Pomian Lewison (San Diego, California) |
| ABSTRACT | A method for visiting a results page of a time-varying result set of a search query. The method includes displaying to a user a list of results belonging to the visited page, each result comprising a hyperlink to a document, a result being de-emphasized if the URL used in its hyperlink is present in a set of URLs of results that are deemed to have been seen by the user. When the user clicks or taps a page menu button to navigate to a different page, the method further includes adding to that set the URLs of the results of the visited page. Page menu buttons are highlighted if they pertain to pages containing results deemed to have been seen by the user. |
| FILED | Monday, April 02, 2012 |
| APPL NO | 13/437927 |
| ART UNIT | 2161 — Data Bases & File Management |
| CURRENT CPC | Data processing: Database and file management or data structures 77/706 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08450256 | Bredsguard |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jakob Bredsguard (Irvine, California) |
| ASSIGNEE(S) | Biosynthetic Technologies, LLC (Irvine, California) |
| INVENTOR(S) | Jakob Bredsguard (Irvine, California) |
| ABSTRACT | Provided herein are compounds of the formula: in which n is an integer equal to or greater than 1; R2 is selected from hydrogen and optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched; and R1, R3, and R4, independently for each occurrence, are selected from optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched, wherein compositions comprising the compounds are characterized by particular combinations of values for estolide number, kinematic viscosity, and pour point. Also provided are compositions containing the compounds and methods of making both the compounds and compositions thereof. |
| FILED | Wednesday, August 31, 2011 |
| APPL NO | 13/199554 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Solid anti-friction devices, materials therefor, lubricant or separant compositions for moving solid surfaces, and miscellaneous mineral oil compositions 58/465 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450364 | Lephart et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Edwin Douglas Lephart (Orem, Utah); Trent D. Lund (Wheaton, Illinois); Kenneth David Reginald Setchell (Cincinnati, Ohio); Robert J. Handa (Fort Collins, Colorado) |
| ASSIGNEE(S) | Brigham Young University (Provo, Utah); Colorado State University Research Foundation (Fort Collins, Colorado); Children's Hospital Medical Center of Cincinnati, Ohio (Cincinnati, Ohio) |
| INVENTOR(S) | Edwin Douglas Lephart (Orem, Utah); Trent D. Lund (Wheaton, Illinois); Kenneth David Reginald Setchell (Cincinnati, Ohio); Robert J. Handa (Fort Collins, Colorado) |
| ABSTRACT | Equol (7-hydroxy-3(4′hydroxyphenyl)-chroman), the major metabolite of the phytoestrogen daidzein, specifically binds and blocks the hormonal action of 5α-dihydrotestosterone (DHT) in vitro and in vivo. Equol can bind circulating free DHT and sequester it from the androgen receptor, thus altering growth and physiological hormone responses that are regulated by androgens. These data suggest a novel model to explain equol's biological properties. The significance of equol's ability to specifically bind and sequester DHT from the androgen receptor have important ramifications in health and disease and may indicate a broad and important usage for equol in the treatment and prevention of androgen-mediated pathologies. Thus, equol can specifically bind DHT and prevent DHT's biological actions in physiological and pathophysiological processes. |
| FILED | Monday, April 09, 2012 |
| APPL NO | 13/442466 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/456 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP23631 | Bliss et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fredrick A. Bliss (Davis, California); Ali A. Almehdi (Davis, California); Theodore M. DeJong (Davis, California); Craig A. Ledbetter (Clovis, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); The United States of America, As Represented By The Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Fredrick A. Bliss (Davis, California); Ali A. Almehdi (Davis, California); Theodore M. DeJong (Davis, California); Craig A. Ledbetter (Clovis, California) |
| ABSTRACT | The new ‘HBOK 27’ rootstock is an ‘OP-F2’ plant from an F1 plant of an intraspecific hybrid between two peach parents that is useful as a commercial under-stock for peach and nectarine cultivars. The ‘HBOK 27’ rootstock has been successfully propagated clonally by leafy cuttings and tissue culture. The ‘HBOK 27’ rootstock is graft compatible with peach scion cultivars, and confers moderate vigor control to the compound trees. Peach trees grown on the ‘HBOK 27’ rootstock are productive, require less pruning than trees on grown on the standard rootstock ‘Nemaguard’, and produce fewer root suckers than ‘Nemaguard’. The ‘HBOK 27’ rootstock shows moderate resistance to root knot nematode [Meloidogyne incognita (race 1) isolate ‘Beltran’] that is slightly less than that of the standard rootstock ‘Nemaguard’. |
| FILED | Wednesday, January 11, 2012 |
| APPL NO | 13/374776 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | Plants PLT/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08449993 | Gentleman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Molly Maureen Gentleman (Niskayuna, New York); James Anthony Ruud (Niskayuna, New York) |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | Molly Maureen Gentleman (Niskayuna, New York); James Anthony Ruud (Niskayuna, New York) |
| ABSTRACT | Articles coated with wetting resistant materials are presented. One embodiment is an article comprising a substrate and a coating having low surface connected porosity disposed on the substrate. The coating comprises an oxide, which comprises aluminum, yttrium, and at least one rare earth element according to the following atomic proportions: (RxY1-x)3Al5O12 where x is in the range from about 0.001 to about 0.999, and where R is at least one of the rare earth elements, Y is yttrium, O is oxygen, and Al is aluminum. |
| FILED | Monday, August 31, 2009 |
| APPL NO | 12/550499 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/701 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450723 | Akkerman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hylke Akkerman (Groningen, Netherlands); Howard Edan Katz (Summit, New Jersey) |
| ASSIGNEE(S) | Alcatel Lucent (Paris, France) |
| INVENTOR(S) | Hylke Akkerman (Groningen, Netherlands); Howard Edan Katz (Summit, New Jersey) |
| ABSTRACT | Semiconductor apparatus comprising: a dielectric layer comprising a surface, a portion of the surface having exposed aromatic groups; and a polycrystalline semiconductor layer comprising an organic semiconductor composition overlying and in contact with the portion of the surface, the organic semiconductor composition comprising a compound comprising a chain-like moiety, the chain-like moiety comprising a conjugated thiophene or phenyl group and comprising alkyl chains at ends of the chain-like moiety. Devices comprising semiconductor apparatus, methods for making semiconductor apparatus, and methods for making devices. |
| FILED | Tuesday, November 04, 2003 |
| APPL NO | 10/701183 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/40 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450774 | Shi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Junxia Shi (Ithaca, New York); Lester Fuess Eastman (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Junxia Shi (Ithaca, New York); Lester Fuess Eastman (Ithaca, New York) |
| ABSTRACT | In one example, we describe a new high performance AlGaN/GaN metal-insulator-semiconductor heterostructure field-effect transistor (MISHFET), which was fabricated using HfO2 as the surface passivation and gate insulator. The gate and drain leakage currents are drastically reduced to tens of nA, before breakdown. Without field plates, for 10 μm of gate-drain spacing, the off-state breakdown voltage is 1035V with a specific on-resistance of 0.9 mΩ-cm2. In addition, there is no current slump observed from the pulse measurements. This is the best performance reported on GaN-based, fast power-switching devices on sapphire, up to now, which efficiently combines excellent device forward, reverse, and switching characteristics. Other variations, features, and examples are also mentioned here. |
| FILED | Monday, July 12, 2010 |
| APPL NO | 13/378043 |
| ART UNIT | 2898 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/189 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 08448514 | Hartmann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mitra J. Hartmann (Evanston, Illinois); Joseph H. Solomon (River Forest, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Mitra J. Hartmann (Evanston, Illinois); Joseph H. Solomon (River Forest, Illinois) |
| ABSTRACT | A sensing device includes an elongated whisker element having a flexible cantilever region and a base region where a change in moment or curvature is generated by bending of the cantilever region when it contacts an object. One or more sensor elements cooperatively associated with the whisker element provide one or more output signals that is/are representative of two orthogonal components of change in moment or curvature at the whisker base region to permit determination of object distance, fluid velocity profile, or object contour (shape) with accounting for lateral slip of the whisker element and frictional characteristics of the object. Multiple sensing devices can be arranged in arrays in a manner to sense object contour without or with adjustment for lateral slip. |
| FILED | Tuesday, July 06, 2010 |
| APPL NO | 12/803761 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring and testing 073/521 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08450541 | Seames et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne S. Seames (Grand Forks, North Dakota); Darrin S. Muggli (Atchison, Kansas); Brian M. Tande (Fargo, North Dakota) |
| ASSIGNEE(S) | The University of North Dakota (Grand Forks, North Dakota) |
| INVENTOR(S) | Wayne S. Seames (Grand Forks, North Dakota); Darrin S. Muggli (Atchison, Kansas); Brian M. Tande (Fargo, North Dakota) |
| ABSTRACT | A method for producing products containing cyclic organic compounds from biomass oil includes adding a biomass oil to a vessel; heating the biomass oil to crack the biomass oil; removing undesired or unreacted materials, heavy ends, and light ends from the cracked biomass oil; and extracting components from the cracked biomass oil to produce a mixture of products containing between 5% and 90% cyclic organic compounds by weight. A method for producing a high-octane aviation fuel with low lead content includes cracking a biomass oil, separating a middle distillate mixture from cracked biomass oil, decarboxylating the middle distillate mixture to produce a mixture of products containing at least about 50% cyclic alkane and alkene compounds by weight, and blending the mixture of products with a fuel having an octane number below 95 to produce an aviation fuel having an octane number of at least 100. |
| FILED | Wednesday, November 25, 2009 |
| APPL NO | 12/626304 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemistry of hydrocarbon compounds 585/240 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 08452408 | Song et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shijie Song (Tampa, Florida); Juan Sanchez-Ramos (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida); Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Shijie Song (Tampa, Florida); Juan Sanchez-Ramos (Tampa, Florida) |
| ABSTRACT | A method of treating neurological deficit in which the brain area affected is focally and precisely stimulated by the transient insertion and subsequent removal of a micro-needle. This insertion and subsequent removal of the micro-needle induces endogenous stem cells to proliferate, migrate and promote the brain's self-repair mechanisms. The micro-needle stimulation causes the birth of new neural cells within the brain as well as mobilizes bone marrow derived cells with a neuronal phenotype to migrate to the site of stimulation to repair and replace damaged neural cells. By repairing and/or replacing injured or dead cells, this approach will slow down the degenerative course of the disease and may result in reversal of symptoms. |
| FILED | Thursday, June 25, 2009 |
| APPL NO | 12/491893 |
| ART UNIT | 3766 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 08451338 | Levin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anat Levin (Brookline, Massachusetts); Peter Sand (Brooklyn, New York); Taeg Sang Cho (Cambridge, Massachusetts); Fredo Durand (Boston, Massachusetts); William T. Freeman (Acton, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Anat Levin (Brookline, Massachusetts); Peter Sand (Brooklyn, New York); Taeg Sang Cho (Cambridge, Massachusetts); Fredo Durand (Boston, Massachusetts); William T. Freeman (Acton, Massachusetts) |
| ABSTRACT | Object motion during camera exposure often leads to noticeable blurring artifacts. Proper elimination of this blur is challenging because the blur kernel is unknown, varies over the image as a function of object velocity, and destroys high frequencies. In the case of motions along a 1D direction (e.g. horizontal), applicants show that these challenges can be addressed using a camera that moves during the exposure. Through the analysis of motion blur as space-time integration, applicants show that a parabolic integration (corresponding to constant sensor acceleration) leads to motion blur that is not only invariant to object velocity, but preserves image frequency content nearly optimally. That is, static objects are degraded relative to their image from a static camera, but all moving objects within a given range of motions reconstruct well. A single deconvolution kernel can be used to remove blur and create sharp images of scenes with objects moving at different speeds, without requiring any segmentation and without knowledge of the object speeds. |
| FILED | Friday, March 28, 2008 |
| APPL NO | 12/058105 |
| ART UNIT | 2662 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Television 348/208.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08449309 | Mosholder |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gary S. Mosholder (Sykesville, Maryland) |
| ASSIGNEE(S) | The United State Government as represented by the Director, National Security Agency (Washington, District of Columbia) |
| INVENTOR(S) | Gary S. Mosholder (Sykesville, Maryland) |
| ABSTRACT | A Universal Serial Bus port protector having a top piece and a tongued planar surface, where the top piece includes a rectangular surface, a rectangular planar surface, a box having an open bottom and an open top, and a shim-like piece, and where the tongued planar surface includes a tongued portion and an untongued portion, where the tongued portion includes one dado and two rabbet cuts and two projections, where the top piece and the tongued planar surface are slideably insertable into and extractable from a Universal Serial Bus port to ensure that no electrical connection is made to the Universal Serial Bus port when the top piece and the tongued planar surface are so inserted. |
| FILED | Wednesday, December 07, 2011 |
| APPL NO | 13/374640 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical connectors 439/148 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 08449854 | Khabashesku et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Valery N. Khabashesku (Houston, Texas); Vladimir P. Filonenko (Troistk Moskovskaya Oblast, Russian Federation); Valeri A. Davydov (Troistk Moskovskaya Oblast, Russian Federation) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Valery N. Khabashesku (Houston, Texas); Vladimir P. Filonenko (Troistk Moskovskaya Oblast, Russian Federation); Valeri A. Davydov (Troistk Moskovskaya Oblast, Russian Federation) |
| ABSTRACT | According to some embodiments, a method of preparing a superhard material involves using mixtures of boron with carbon nitride of C3N4 stoichiometry as precursors. The C3N4 may be nanospherical. The result of chemical interaction of these components is the formation of new ternary compound B—C—N compound with a cubic structure. According to some embodiments, the composition is BCxN, where x is about 0.5. According to some embodiments, the composition is BCxN, where x is about 0.2. According to some embodiments, the compound has a unit cell parameter a=3.645±0.005 Å. According to some embodiments, the unit cell parameter a is about 3.655 Å. Synthesis is carried out under the conditions of thermodynamic stability of diamond at pressures higher that 6.0 GPa and temperatures above 1000° C. The starting components are taken according to the following ratio: boron—20-60 wt. %, C3N4—40-80 wt. %. |
| FILED | Tuesday, January 29, 2008 |
| APPL NO | 12/524951 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/276 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451062 | Seefeldt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James D. Seefeldt (Eden Prairie, Minnesota); Keith Golke (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | James D. Seefeldt (Eden Prairie, Minnesota); Keith Golke (Minneapolis, Minnesota) |
| ABSTRACT | This disclosure is directed to techniques for preventing or reducing perturbations of an output signal of a differential amplifier caused by ionizing radiation incident upon the amplifier. The amplifier may include an amplification module that includes a plurality of amplification units configured to amplify a difference between a first component and a second component of a differential voltage signal to generate a plurality of amplified difference signals each corresponding to the amplified difference. The amplifier may further include a combination module that combines the plurality of amplified difference signals to generate a common output signal corresponding to the amplified difference. |
| FILED | Monday, July 25, 2011 |
| APPL NO | 13/190285 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Amplifiers 330/295 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08451666 | Perner |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frederick Perner (Santa Barbara, California) |
| ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
| INVENTOR(S) | Frederick Perner (Santa Barbara, California) |
| ABSTRACT | A method for reading a memory element within a crossbar array, the method including selecting a column line connected to a target memory element of the crossbar array by applying a supply voltage to a source follower, a gate terminal of the source follower connected to the column line; applying bias voltages to row lines of the crossbar array; storing an output voltage of the source follower in a storage element; applying a sense voltage to a row line connected to the target memory element; and outputting a difference between the voltage stored in the storage element and an output voltage of the source follower while the sense voltage is applied to the row line. |
| FILED | Wednesday, May 26, 2010 |
| APPL NO | 12/787857 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/189.11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, May 28, 2013.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20130528.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page