FedInvent™ Patents
Patent Details for Tuesday, June 18, 2013
This page was updated on Monday, March 27, 2023 at 03:48 AM GMT
Department of Defense (DOD)
| US 08464493 | Boone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nicholas Boone (Vicksburg, Mississippi); Bartley P. Durst (Clinton, Mississippi); Toney K. Cummins (Vicksburg, Mississippi); Pamela G. Kinnebrew (Vicksburg, Mississippi); William F. Heard (Clinton, Mississippi); Thomas R. Slawson (Vicksburg, Mississippi); Michael J. Roth (Raymond, Mississippi); Ryan Stinson (Prairieville, Louisiana); Reed Mosher (Vicksburg, Mississippi); Jerry C. Edwards (Huntsville, Alabama); Andrew B. Edwards (Toney, Alabama); Jason D. Edwards (Meridianville, Alabama); Shane H. Sanford (Franklin, Tennessee); Robert A. Pilgrim (Benton, Kentucky) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Nicholas Boone (Vicksburg, Mississippi); Bartley P. Durst (Clinton, Mississippi); Toney K. Cummins (Vicksburg, Mississippi); Pamela G. Kinnebrew (Vicksburg, Mississippi); William F. Heard (Clinton, Mississippi); Thomas R. Slawson (Vicksburg, Mississippi); Michael J. Roth (Raymond, Mississippi); Ryan Stinson (Prairieville, Louisiana); Reed Mosher (Vicksburg, Mississippi); Jerry C. Edwards (Huntsville, Alabama); Andrew B. Edwards (Toney, Alabama); Jason D. Edwards (Meridianville, Alabama); Shane H. Sanford (Franklin, Tennessee); Robert A. Pilgrim (Benton, Kentucky) |
| ABSTRACT | A configuration, all components of which are man portable in some embodiments, for holding panels to protect assets against external force and impacts from airborne projectiles. An open box-like stackable frame module holds panels along a side of the frame. Multiple frames are connected to construct a protective barrier, such as a wall. Frames include provisions for connection in a vertical configuration so as to allow stacking of the frames to increase the height of the barrier. A method of installing is also provided. |
| FILED | Monday, March 02, 2009 |
| APPL NO | 12/920499 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Static structures 052/646 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08464640 | Sawka |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne N. Sawka (Reno, Nevada) |
| ASSIGNEE(S) | Digital Solid State Propulsion LLC (Reno, Nevada) |
| INVENTOR(S) | Wayne N. Sawka (Reno, Nevada) |
| ABSTRACT | A thruster stack assembly and method for manufacturing the same is provided. The thruster stack assembly includes a plurality of grain elements having a common core region (e.g., a channel or passageway), where each grain element comprises a volume of electrically ignitable propellant. The thruster stack assembly further includes electrodes associated with the plurality of grain elements, the electrodes adapted for selectively igniting the plurality of grain elements. In one example, one or more of the grain elements may be ignited and combusted without igniting or damaging adjacent grain elements of the stack. The core region serves to channel combustion gases and exhaust from the thruster stack. Multiple stacks may be assembled together to form three-dimensional thruster arrays. |
| FILED | Thursday, May 05, 2011 |
| APPL NO | 13/101934 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Ammunition and explosives 12/291 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08464745 | Ringer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles Ringer (San Diego, California) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Charles Ringer (San Diego, California) |
| ABSTRACT | A pressure equalizer for an underwater vessel can include a pneumatic reservoir and a pressure compensating valve (PCV). The PCV can be in fluid communication with the surrounding underwater environment and the vessel interior, and in selective fluid communication with the reservoir. The PCV can further include a valve body and a valve plug. As the PCV opens, the plug moves within the body to establish a path of fluid communication from the reservoir, through the PCV to the vessel interior, to allow flow of high pressure compressible fluid from the reservoir into the interior to pressurize the vessel interior. As the vessel interior pressure equalizes with the surrounding environment, the plug moves within the body to close the fluid communication path with the reservoir, thereby stopping the flow of compressible fluid into the vessel interior to maintain the equalized pressure. |
| FILED | Tuesday, November 02, 2010 |
| APPL NO | 12/917594 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid handling 137/81.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08464981 | Goldie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James Goldie (Lexington, Massachusetts); Nicholas Vitale (Albany, New York); George A. Downey (Arlington, Massachusetts); Kevin Leary (Hamilton, Massachusetts); William Hafer (College Station, Texas) |
| ASSIGNEE(S) | Infoscitex Corporation (Waltham, Massachusetts) |
| INVENTOR(S) | James Goldie (Lexington, Massachusetts); Nicholas Vitale (Albany, New York); George A. Downey (Arlington, Massachusetts); Kevin Leary (Hamilton, Massachusetts); William Hafer (College Station, Texas) |
| ABSTRACT | A UAV recovery system including a recovery cart; a guide mechanism for defining the path of the cart; a base station for capturing a UAV tailhook; a momentum transfer system driven by the inertia of the UAV through the arresting member to move the recovery cart along the guide mechanism away from the base station in the same direction as the UAV; an acceleration control device for converging the speeds and positions of the UAV and cart for enabling engagement of the cart and UAV as their relative speeds approach zero; and a brake system for stopping the recovery cart when the cart and UAV are engaged. Also disclosed is a UAV having a tailhook pivotably mounted on the UAV at the center of gravity of the UAV. |
| FILED | Wednesday, January 26, 2011 |
| APPL NO | 12/931230 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeronautics and astronautics 244/110.E00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465242 | Arendt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott P. Arendt (APO, None); Rodolfo Jesus Bernal (Fredericksburg, Virginia); Vladimir Fabian (Arlington, Virginia); Thomas E. Jean (Hague, Virginia); Carl S. Lynn, IV (Fredericksburg, Virginia); Kevin G. Smith (King George, Virginia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Scott P. Arendt (APO, None); Rodolfo Jesus Bernal (Fredericksburg, Virginia); Vladimir Fabian (Arlington, Virginia); Thomas E. Jean (Hague, Virginia); Carl S. Lynn, IV (Fredericksburg, Virginia); Kevin G. Smith (King George, Virginia) |
| ABSTRACT | A self-contained fastener is provided for attaching to a structure having opposing edges that flank a cavity across a gap. The fastener includes a grip member, a clamp member and a latch member. The grip member has a knob and an inner annulus disposed thereon along an axis of symmetry. The knob has a central through-hole coaxial with the inner annulus. The inner annulus has an arc tab that radially protrudes therefrom. The clamp member includes a boss and an outer annulus disposed thereon. The boss has first and second dimensions perpendicular to the axis, the first dimension being shorter than the gap. The clamp member is flanked by opposing ledges along the second dimension. Each ledge is arranged to engage a respective edge of the structure. The inner annulus is coaxially insertable into the outer annulus. The latch member includes a stud and a flange. The stud is insertable at a proximal end into the inner annulus and the through-hole. The flange is disposed at a distal end of the stud and has a third dimension shorter than the gap. The flange and the block can be inserted into the cavity along the respective third and first dimensions through the gap. In response to clockwise turning, the knob rotates the tab within the angular notch until inhibited by the outer annulus, whereby the proximal end of the stud retracts into the through-hole, thereby engaging the fastener to the structure. |
| FILED | Wednesday, December 08, 2010 |
| APPL NO | 12/930166 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Expanded, threaded, driven, headed, tool-deformed, or locked-threaded fastener 411/551 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465295 | Taskovics et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven M. Taskovics (Framingham, Massachusetts); Brett H. Kobelin (Billerica, Massachusetts); Marc S. Pepi (Sudbury, Massachusetts); Steven R. Mitchell (Danville, New Hampshire) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Steven M. Taskovics (Framingham, Massachusetts); Brett H. Kobelin (Billerica, Massachusetts); Marc S. Pepi (Sudbury, Massachusetts); Steven R. Mitchell (Danville, New Hampshire) |
| ABSTRACT | A fluid percussion system for modeling penetrating brain injury includes a fluid percussion device that takes inputs in the form of pressurized gas and electrical signals from a computer and outputs a single hydraulic pulse, or multiple hydraulic pulses in quick succession. The fluid percussion device may include a pneumatic cylinder assembly and a hydraulic cylinder assembly that is actuated by the pneumatic cylinder assembly to produce the hydraulic pulse(s) of pressurized fluid. Each pulse may be used to rapidly inflate and deflate an attached balloon (representing a brain penetrating device). The balloon may be inserted in a test specimen, and the rapid inflation and deflation of the balloon creates a lesion that simulates a penetrating brain injury. A calibration system that employs an optical sensor may be used to determine maximum balloon diameter achieved during rapid inflation. |
| FILED | Wednesday, February 06, 2008 |
| APPL NO | 12/027142 |
| ART UNIT | 3711 — Amusement and Education Devices |
| CURRENT CPC | Education and demonstration 434/270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465373 | Dornfeld et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael S. Dornfeld (Avon, Indiana); Douglas Michael Roever (Indianapolis, Indiana); Mark Potter (Carmel, Indiana); Gregory Blake (Moblesville, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Michael S. Dornfeld (Avon, Indiana); Douglas Michael Roever (Indianapolis, Indiana); Mark Potter (Carmel, Indiana); Gregory Blake (Moblesville, Indiana) |
| ABSTRACT | The present invention contemplates a face coupling, and contemplates a gas turbine engine having a face coupling. The face coupling includes a plurality of driving teeth extending from a first component, and a plurality of driven teeth extending from a second component. The plurality of driving teeth and the plurality of driven teeth cooperate to transmit a torque load from the first component to second component. The plurality of driven teeth include a root transition for preventing a driving tooth tip edge from contacting an adjacent driven tooth. |
| FILED | Thursday, September 23, 2010 |
| APPL NO | 12/889029 |
| ART UNIT | 3679 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Rotary shafts, gudgeons, housings, and flexible couplings for rotary shafts 464/157 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465590 | Kelekar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rajesh Kelekar (Los Altos, California) |
| ASSIGNEE(S) | Intermolecular, Inc. (San Jose, California) |
| INVENTOR(S) | Rajesh Kelekar (Los Altos, California) |
| ABSTRACT | A substrate for processing in a heating system is disclosed. The substrate includes a bottom portion for absorbing heat from a radiating heat source, the bottom portion having a first region having a first emissivity and a second region having a second emissivity less than the first emissivity. The first region and the second region promote thermal uniformity of the substrate by compensating for thermal non-uniformity of the radiating heat source. |
| FILED | Tuesday, February 01, 2011 |
| APPL NO | 13/019268 |
| ART UNIT | 2826 — Semiconductors/Memory |
| CURRENT CPC | Coating apparatus 118/715 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465606 | Redding et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David R. Redding (Edgewood, Maryland); Gene V. Tracy (Jarrettsville, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | David R. Redding (Edgewood, Maryland); Gene V. Tracy (Jarrettsville, Maryland) |
| ABSTRACT | A composition of matter for an incendiary device includes a thermate component consisting of strontium nitrate Gr A, black iron oxide Gr B, aluminum Gr D Cl 5, aluminum Gr E Cl 6, sulfur Gr E, and polyacrylic rubber; and an ignition component consisting of potassium nitrate, titanium, aluminum, silicon, sulfur, charcoal, and polyacrylic rubber, wherein the thermate component consists of a barium nitrate free thermate formulation, and wherein the ignition component consists of a lead free ignition formulation. A parts by weight composition of the thermate component consists of 20.59% strontium nitrate Gr A, 48.04% black iron oxide Gr B, 17.57% aluminum Gr D Cl 5, 9.88% aluminum Gr E Cl 6, 1.96% sulfur Gr E, and 1.96% polyacrylic rubber, and a parts by weight composition of the ignition component consists of 66% potassium nitrate, 11% titanium, 8% aluminum, 6% silicon, 2% sulfur, 5% charcoal, and 2% polyacrylic rubber. Preferably, the first and second components are consolidated together using a ram having a sharp-edged profile. |
| FILED | Friday, January 16, 2009 |
| APPL NO | 12/355348 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/37 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465607 | Kelley |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John M. Kelley (Owings Mills, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John M. Kelley (Owings Mills, Maryland) |
| ABSTRACT | A method, and a related material, for utilizing high performance solid rocket propellants, which are molding powders. A propellant molding powder are selected to have a design burning rate and a tailored compaction profile. A morphology of a center-port of a rocket is selected for the design burn rate and a spin-rate. The molding powder is compacted isostatically around a core through application of triaxial pressure therein forming a solid rocket propellant charge with the selected center-port shape. The solid rocket propellant charge is placed in a cartridge or a case. The cartridge is selected from various types of cartridges and specialty charges. The solid rocket propellant molding powders are highly filled with metallic fuels, and have a binder in the range of 4% to 18%, which at least partially coats the surface of the molding powder. |
| FILED | Thursday, September 18, 2008 |
| APPL NO | 12/284476 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/87 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465608 | Coffey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kevin R. Coffey (Oviedo, Florida); Edward Alan Dein (Saint Cloud, Florida); Bo Yao (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Kevin R. Coffey (Oviedo, Florida); Edward Alan Dein (Saint Cloud, Florida); Bo Yao (Orlando, Florida) |
| ABSTRACT | A method for forming a metastable intermolecular composite (MIC) includes providing a vacuum level of <10−8 torr base pressure in a deposition chamber. A first layer of a first material of a metal that is reactive with water vapor is deposited, followed by depositing a second layer of a second material of a metal oxide on the first layer. The first and second material are capable of an exothermic chemical reaction to form at least one product, and the first and second layer are in sufficiently close physical proximity so that upon initiation of the exothermic reaction the reaction develops into a self initiating chemical reaction. An interfacial region averaging <1 nm thick is formed between the first layer and second layer from a reaction of the first material with water vapor. In one embodiment, the first material is Al and the second material is CuOx. |
| FILED | Friday, September 28, 2012 |
| APPL NO | 13/630637 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosive and thermic compositions or charges 149/109.600 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465678 | Swager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Timothy M. Swager (Newton, Massachusetts); Jye-Shane Yang (Ping-Chen, Taiwan); Vance Williams (Vancouver, Canada); Yijun Miao (Falls Church, Virginia); Claus G. Lugmair (San Jose, California); Igor A. Levitsky (Fall River, Massachusetts); Jinsang Kim (Ann Arbor, Michigan); Robert Deans (Grafton, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy M. Swager (Newton, Massachusetts); Jye-Shane Yang (Ping-Chen, Taiwan); Vance Williams (Vancouver, Canada); Yijun Miao (Falls Church, Virginia); Claus G. Lugmair (San Jose, California); Igor A. Levitsky (Fall River, Massachusetts); Jinsang Kim (Ann Arbor, Michigan); Robert Deans (Grafton, Massachusetts) |
| ABSTRACT | The present invention relates to a class of luminescent and conductive polymer compositions having chromophores, and particularly solid films of these compositions exhibiting increased luminescent lifetimes, quantum yields and amplified emissions. These desirable properties can be provided through polymers having rigid groups designed to prevent polymer reorganization, aggregation or π-stacking upon solidification. These polymers can also display an unusually high stability with respect to solvent and heat exposures. The invention also relates to a sensor and a method for sensing an analyte through the luminescent and conductive properties of these polymers. Analytes can be sensed by activation of a chromophore at a polymer surface. Analytes include aromatics, phosphate ester groups and in particular explosives and chemical warfare agents in a gaseous state. The present invention also relates to devices and methods for amplifying emissions by incorporating a polymer having an energy migration pathway and/or providing the polymer as a block co-polymer or as a multi-layer. |
| FILED | Friday, April 01, 2011 |
| APPL NO | 13/078658 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Compositions 252/500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465712 | Rong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Charles Rong (Rockville, Maryland); Rongzhong Jiang (Olnay, Maryland); Deryn Chu (Potomac, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Charles Rong (Rockville, Maryland); Rongzhong Jiang (Olnay, Maryland); Deryn Chu (Potomac, Maryland) |
| ABSTRACT | A method and system for desulfurization comprising first and second metal oxides; a walled enclosure having an inlet and an exhaust for the passage of gas to be treated; the first and second metal oxide being combinable with hydrogen sulfide to produce a reaction comprising a sulfide and water; the first metal oxide forming a first layer and the second metal oxide forming a second layer within the walled surroundings; the first and second layers being positioned so the first layer removes the bulk amount of the hydrogen sulfide from the treated gas prior to passage through the second layer, and the second layer removes substantially all of the remaining hydrogen sulfide from the treated gas; the first metal oxide producing a stoichiometrical capacity in excess of 500 mg sulfur/gram; the second metal oxide reacts with the hydrogen sulfide more favorably but has a stoichometrical capacity which is less than the first reactant; whereby the optimal amount by weight of the first and second metal oxides is achieved by utilizing two to three units by weight of the first metal oxide for every unit of the second metal oxide. |
| FILED | Thursday, November 12, 2009 |
| APPL NO | 12/617197 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465775 | DeSimone et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Edward T. Samulski (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Joseph M. DeSimone (Chapel Hill, North Carolina); Edward T. Samulski (Chapel Hill, North Carolina) |
| ABSTRACT | A plurality of artificial red blood cell particles includes each particle of the plurality being substantially monodisperse and each particle having a largest common linear dimension of about 5 μm to about 10 μm. The particles can also have a modulus configured such that a particle of the plurality of particles can pass through a tube having an inner diameter of less than about 3 μm. |
| FILED | Friday, July 27, 2007 |
| APPL NO | 12/374182 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 9/0026 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 514/832 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465847 | Shaw et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John A. Shaw (Ann Arbor, Michigan); David S. Grummon (East Lansing, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan); Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | John A. Shaw (Ann Arbor, Michigan); David S. Grummon (East Lansing, Michigan) |
| ABSTRACT | This invention discloses a method, using pure niobium as a transient liquid reactive braze material, for fabrication of cellular or honeycomb structures, wire space-frames or other sparse builtup structures or discrete articles using Nitinol (near-equiatomic titanium-nickel alloy) and related shape-memory and superelastic alloys. Nitinol shape memory alloys (SMAs), acquired in a form such as corrugated sheet, discrete tubes or wires, may be joined together using the newly discovered joining technique. Pure niobium when brought into contact with nitinol at elevated temperature, liquefies at temperatures below the melting point and flows readily into capillary spaces between the elements to be joined, thus forming a strong joint. |
| FILED | Saturday, August 07, 2010 |
| APPL NO | 12/852456 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/616 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465851 | Thompson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark E. Thompson (Anaheim Hills, California); Raymond Kwong (Plainsboro, New Jersey); Yeh-Jiun Tung (Princeton, New Jersey); Jason Brooks (Lambertville, New Jersey) |
| ASSIGNEE(S) | Universal Display Corporation (Ewing, New Jersey); The University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Mark E. Thompson (Anaheim Hills, California); Raymond Kwong (Plainsboro, New Jersey); Yeh-Jiun Tung (Princeton, New Jersey); Jason Brooks (Lambertville, New Jersey) |
| ABSTRACT | A device is provided, having an anode, a cathode, and two adjacent organic layers disposed between the anode and the cathode. One organic layer is a phosphorescent emissive material. The other organic layer may comprise an aromatic hydrocarbon material, comprising an aromatic non-heterocyclic hydrocarbon core optionally substituted, and wherein the substituents are the same or different, and each is selected from the group consisting of alkyl, alkenyl, alkynyl, aryl, heteroalkyl, substituted aryl, substituted heteroaryl and heterocyclic groups. The second organic layer may comprise a material having a molecular dipole moment less than about 2.0 debyes, such that the device has an unmodified external quantum efficiency of at least about 3% and a lifetime of at least about 1000 hours at an initial luminance of about 100 to about 1000 cd/m2. |
| FILED | Thursday, December 22, 2011 |
| APPL NO | 13/334498 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Stock material or miscellaneous articles 428/690 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465910 | Singer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jonathan Phillip Singer (Media, Pennsylvania); Jae-Hwang Lee (Chestnut Hill, Massachusetts); Steven E. Kooi (Lexington, Massachusetts); Edwin Lorimer Thomas (Natick, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jonathan Phillip Singer (Media, Pennsylvania); Jae-Hwang Lee (Chestnut Hill, Massachusetts); Steven E. Kooi (Lexington, Massachusetts); Edwin Lorimer Thomas (Natick, Massachusetts) |
| ABSTRACT | Lithographic Method. The method fabricates complex structures and includes depositing a photoresist onto a substrate, the photoresist including a predominantly thermal band of optical absorption possibly due to the incorporation of a doping agent. A three-dimensional pattern is generated within the resist using a first wavelength of light to effect activation of a photoinitiator to produce a latently photostructured resist. Focused laser spike annealing of the photostructured resist with a second wavelength of light selected to be absorbed by the thermally absorbing band to accelerate the photoinduced reaction in the resist is provided. Three-dimensional direct writing may be performed within the resist to define features not part of the interference pattern and the resist is developed to produce the complex structure. |
| FILED | Wednesday, June 29, 2011 |
| APPL NO | 13/171954 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Radiation imagery chemistry: Process, composition, or product thereof 430/325 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465966 | Ewert |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Matt Ewert (St. Petersburg Beach, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Matt Ewert (St. Petersburg Beach, Florida) |
| ABSTRACT | The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample. |
| FILED | Thursday, May 08, 2008 |
| APPL NO | 12/117505 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/262 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466167 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tom Yao Hsiang Wu (San Diego, California); Yongkai Li (San Diego, California); Alex Cortez (San Diego, California); Yefen Zou (San Diego, California); Pranab Mishra (San Diego, California); Xiaoyue Zhang (San Diego, California); David Skibinski (Siena, Italy); Manmohan Singh (Lexington, Massachusetts); Nicholas Valiante (Cambridge, Massachusetts) |
| ASSIGNEE(S) | IRM LLC (Hamilton, Bermuda); Novartis AG (Basel, Switzerland) |
| INVENTOR(S) | Tom Yao Hsiang Wu (San Diego, California); Yongkai Li (San Diego, California); Alex Cortez (San Diego, California); Yefen Zou (San Diego, California); Pranab Mishra (San Diego, California); Xiaoyue Zhang (San Diego, California); David Skibinski (Siena, Italy); Manmohan Singh (Lexington, Massachusetts); Nicholas Valiante (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with Toll-Like Receptors, including TLR7 and TLR8. In one aspect, the compounds are useful as adjuvants for enhancing the effectiveness of a vaccine (formula I) wherein: X3 is N; X4 is N Or CR3; X5 is —CR4═CR5. |
| FILED | Friday, February 27, 2009 |
| APPL NO | 12/921129 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/292 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466317 | Stec, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel Stec, III (Long Valley, New Jersey); Kathy Yang (Ledgewood, New Jersey); Gartung Cheng (Edison, New Jersey); Neha Mehta (Succasunna, New Jersey); Paritosh R. Dave (Bridgewater, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Daniel Stec, III (Long Valley, New Jersey); Kathy Yang (Ledgewood, New Jersey); Gartung Cheng (Edison, New Jersey); Neha Mehta (Succasunna, New Jersey); Paritosh R. Dave (Bridgewater, New Jersey) |
| ABSTRACT | A method for preparing an insensitive bis(2,2-dinitropropyl)nitramine (BDNPN) as a fine powder which exhibits desirable insensitive munitions (IM) characteristics for use alone or compounded with other energetic materials such as RDX. |
| FILED | Wednesday, July 06, 2011 |
| APPL NO | 13/176996 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 564/110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466686 | Jones et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Galvin Jones (Louisville, Kentucky); Joseph E. Yates (Crestwood, Kentucky) |
| ASSIGNEE(S) | Louisville Solutions Incorporated (Louisville, Kentucky) |
| INVENTOR(S) | Galvin Jones (Louisville, Kentucky); Joseph E. Yates (Crestwood, Kentucky) |
| ABSTRACT | A test system for taking a sample of a constituent on a surface utilizing a fluid source includes an upper body and a concomitant mating lower body that includes an aperture in a portion thereof. A central fiber portion and a support extend through upper body aperture to provide a consistent surface for contacting the surface to be tested. |
| FILED | Friday, November 05, 2010 |
| APPL NO | 12/940180 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466687 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | C. Christopher Reed (El Segundo, California); Tom R. Newbauer (Claremont, California); Richard Briët (Cypress, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | C. Christopher Reed (El Segundo, California); Tom R. Newbauer (Claremont, California); Richard Briët (Cypress, California) |
| ABSTRACT | A system including a charge source and at least one voltage measurement device is disclosed. The charge source is for generating a charging environment to produce at least one of a voltage profile and a current on an area of dielectric material disposed over a conductive substrate. The area of dielectric material includes a first area containing a subsurface defect. The area of dielectric material also includes a second area that is defect-free. The at least one voltage measurement device is for outputting voltage measurements at different positions over the area of dielectric material. The voltage measurements over the first area differ from voltage measurements over the second area to define a voltage differential. |
| FILED | Monday, September 20, 2010 |
| APPL NO | 12/924099 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Measuring and testing 324/454 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466736 | Reynolds |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Scott K. Reynolds (Amawalk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Scott K. Reynolds (Amawalk, New York) |
| ABSTRACT | A circuit includes an amplifier having an input and an output; and at least one transistor comprising at least one terminal and at least one isolated well. The input of the amplifier is electrically connected to the at least one terminal of the transistor; and the output of the amplifier is electrically connected to the at least one isolated well of the at least one transistor. |
| FILED | Friday, April 13, 2012 |
| APPL NO | 13/446115 |
| ART UNIT | 2816 — Semiconductors/Memory |
| CURRENT CPC | Miscellaneous active electrical nonlinear devices, circuits, and systems 327/427 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466816 | Denham |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Martin S. Denham (Bend, Oregon) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Martin S. Denham (Bend, Oregon) |
| ABSTRACT | A circuit for serializing bits including a clock circuit and a serializer. The clock circuit may be configured to generate a plurality of clock signals from a received master clock signal. A plurality of bits may be transmitted to the serializer in response to a transition of a first clock signal. The serializer may comprise a system of latches and a rotary circuit. The system of latches may be configured to receive a first half of the plurality of bits in response to a first transition of a second clock signal and to receive a second half of the plurality of bits in response to a transition of a third clock signal. The rotary circuit may be configured to receive the plurality of bits from the system of latches and to output each bit at a particular time based on a plurality of rotary clock signals. |
| FILED | Thursday, April 19, 2012 |
| APPL NO | 13/451115 |
| ART UNIT | 2819 — Semiconductors/Memory |
| CURRENT CPC | Coded data generation or conversion 341/101 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466832 | Afshari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ehsan Afshari (Newfield, New York); Omeed Momeni (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Ehsan Afshari (Newfield, New York); Omeed Momeni (Ithaca, New York) |
| ABSTRACT | Doppler-inspired methods for signal generation and frequency up-conversion are provided that are compatible with CMOS technology. In accordance with an embodiment, a circuit is provided that includes two input signals that can propagate on artificial transmission lines in opposite directions, resembling the relative movement of source and observer in Doppler frequency shift; and an output signal combiner. By controlling the characteristics of the transmission lines and the input signal frequencies, the harmonic generation of active devices is utilized and combined to provide the desired high-frequency component at the output. |
| FILED | Tuesday, September 28, 2010 |
| APPL NO | 12/892210 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/175 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466835 | Elwell, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John M. Elwell, Jr. (Sudbury, Massachusetts); Robert D. Tingley (Charlestown, Massachusetts) |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | John M. Elwell, Jr. (Sudbury, Massachusetts); Robert D. Tingley (Charlestown, Massachusetts) |
| ABSTRACT | A non-GPS satellite-based system enables correction of a local clock in a user device to facilitate GPS-based location determination. |
| FILED | Friday, May 13, 2011 |
| APPL NO | 13/107618 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/357.620 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466964 | Gat et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nahum Gat (Manhattan Beach, California); Jason Kriesel (Long Beach, California) |
| ASSIGNEE(S) | Opto-Knowledge Systems, Inc. (Torrance, California) |
| INVENTOR(S) | Nahum Gat (Manhattan Beach, California); Jason Kriesel (Long Beach, California) |
| ABSTRACT | A multispectral thermal infrared camera system is disclosed. An uncooled thermal imaging camera is equipped with an axially tilted, cooled spectral filter. The axially tilted, cooled spectral filter deflects the radiation emitted by the uncooled camera away from being reflected back into the camera. The axially tilted, cooled spectral filter emits a lesser amount of thermal radiation towards the camera. And the axially tilted, cooled tilted filter is enclosed in a cold radiation shield to minimize the thermal emission that would be reflected by the filter towards the camera and to absorb the radiation deflected by the tilted filter. The axially tilted, cooled spectral filter passes only the desired portion of the thermal infrared radiation from the scene onto the uncooled camera. |
| FILED | Wednesday, April 02, 2008 |
| APPL NO | 12/060881 |
| ART UNIT | 2486 — Recording and Compression |
| CURRENT CPC | Television 348/164 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467056 | Haycraft |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James Joseph Haycraft (Ridgecrest, California) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | James Joseph Haycraft (Ridgecrest, California) |
| ABSTRACT | A light scattering apparatus and methods for using a light scattering apparatus that performs at angles other than the standard 90 or 180 degrees and can analyze a variety of samples including, but not limited to, solids, crystals, liquids, gases and combinations thereof. |
| FILED | Monday, November 09, 2009 |
| APPL NO | 12/615164 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/364 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467122 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xuezhe Zheng (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California) |
| ASSIGNEE(S) | Oracle America, Inc. (Redwood Shores, California) |
| INVENTOR(S) | Xuezhe Zheng (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California) |
| ABSTRACT | A laser source includes a semiconductor optical amplifier (SOA) as a gain medium that receives and amplifies an optical signal characterized by at least a wavelength associated with a lasing mode of the laser source. This laser source includes a first optical waveguide and a second optical waveguide optically coupled to the SOA. Furthermore, a wavelength-selective reflector is optically coupled to the first optical waveguide and the second optical waveguide, where a closed loop defined by the SOA, the first optical waveguide, the wavelength-selective reflector and the second optical waveguide defines a cavity of the laser source. |
| FILED | Wednesday, July 13, 2011 |
| APPL NO | 13/182227 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical: Systems and elements 359/333 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467253 | Perner |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Frederick Perner (Santa Barbara, California) |
| ASSIGNEE(S) | Hewlett-Packard Development Company, L.P. (Houston, Texas) |
| INVENTOR(S) | Frederick Perner (Santa Barbara, California) |
| ABSTRACT | A method for reading the state of a memory element within a crossbar memory array includes storing a first electric current sensed from a half-selected target memory element within the crossbar memory array; and outputting a final electric current based on the stored first electric current and a second electric current sensed from the target memory element when the target memory element is fully selected. |
| FILED | Monday, May 24, 2010 |
| APPL NO | 12/786073 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Static information storage and retrieval 365/189.50 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467269 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shengli Zhou (Mansfield, Connecticut); Peter Willett (Coventry, Connecticut); Christian Berger (Pittsburgh, Pennsylvania); Sean Mason (Nashua, New Jersey) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Shengli Zhou (Mansfield, Connecticut); Peter Willett (Coventry, Connecticut); Christian Berger (Pittsburgh, Pennsylvania); Sean Mason (Nashua, New Jersey) |
| ABSTRACT | Advantageous online and/or real-time OFDM-based underwater acoustic (UWA) apparatus, systems and methods are provided according to the present disclosure. The apparatus, systems and methods employ a receiver with a bank of parallel branches, with each branch having a self-correlator matched to a different waveform scaling factor. A detection is declared when any of the branches leads to a correlation metric larger than a pre-defined threshold. The branch with the largest metric yields a Doppler scale estimate and a coarse synchronization point. The proposed apparatus, systems and methods use one OFDM preamble, thereby avoiding the need to buffer the whole data packet before data demodulation and enabling online and/or real-time operation. Thus, the disclosed apparatus, systems and methods are advantageously applicable to UWA communications. |
| FILED | Thursday, April 01, 2010 |
| APPL NO | 12/752239 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/134 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467548 | Karunasiri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gamani Karunasiri (Pacific Grove, California); Jose Sinibaldi (Carmel, California) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Gamani Karunasiri (Pacific Grove, California); Jose Sinibaldi (Carmel, California) |
| ABSTRACT | A micro-electromechanical (MEMS) based directional sound sensor includes a two sensor wings attached to a surrounding support structure by two legs. The support structure is hollow beneath the sensor wings allowing the sensor wings to vibrate in response to sound excitation. In one embodiment, interdigitated comb finger capacitors attached on the sensor wing edges and the support structure enable an electrostatic (capacitive) readout related to the vibrations of the sensor which allows determination of the sound direction. |
| FILED | Wednesday, April 07, 2010 |
| APPL NO | 12/756040 |
| ART UNIT | 2651 — Videophones and Telephonic Communications |
| CURRENT CPC | Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 1/406 (20130101) H04R 3/00 (20130101) Original (OR) Class H04R 3/005 (20130101) H04R 9/08 (20130101) H04R 19/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467628 | Coffman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Thayne R. Coffman (Austin, Texas) |
| ASSIGNEE(S) | 21 CT, Inc. (Austin, Texas) |
| INVENTOR(S) | Thayne R. Coffman (Austin, Texas) |
| ABSTRACT | A stochastic method and system for fast stereoscopic ranging includes selecting a pair of images for stereo processing, in which the pair of images are a frame pair and one of the image is a reference frame, seeding estimated values for a range metric at each pixel of the reference frame, initializing one or more search stage constraints, stochastically computing local influence for each valid pixel in the reference frame, aggregating local influences for each valid pixel in the reference frame, refining the estimated values for the range metric at each valid pixel in the reference frame based on the aggregated local influence, and post-processing range metric data. A valid pixel is a pixel in the reference frame that has a corresponding pixel in the other frame of the frame pair. The method repeats n iterations of the stochastically computing through the post-processing. |
| FILED | Thursday, April 24, 2008 |
| APPL NO | 12/451064 |
| ART UNIT | 2624 — Selective Visual Display Systems |
| CURRENT CPC | Image analysis 382/285 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467632 | Zheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xuezhe Zheng (San Diego, California); John E. Cunningham (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California) |
| ASSIGNEE(S) | Oracle America, Inc. (Redwood Shores, California) |
| INVENTOR(S) | Xuezhe Zheng (San Diego, California); John E. Cunningham (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California) |
| ABSTRACT | During operation of an electro-absorption modulator, an optical signal is conveyed, using an optical waveguide in the electro-absorption modulator, to a semiconductor layer that substantially fills a gap between two portions of the optical waveguide. Then, the optical signal is electro-absorption modulated by selectively applying a voltage to electrodes that produces an electric field, approximately perpendicular to the midline of the optical waveguide, in the semiconductor layer. These electrodes are coupled to the edges of the semiconductor layer at the periphery along the width of the semiconductor layer by intervening layers. Furthermore, the intervening layers include a material that has a lower index of refraction than the semiconductor layer, and a lower optical absorption than the electrodes. |
| FILED | Thursday, January 06, 2011 |
| APPL NO | 12/986062 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical waveguides 385/1 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467739 | Vajha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sasidhar Vajha (Brooklyn Park, Minnesota); Timothy T. Childs (Minnetonka, Minnesota); Daniel C. Eller (Silver Lake, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sasidhar Vajha (Brooklyn Park, Minnesota); Timothy T. Childs (Minnetonka, Minnesota); Daniel C. Eller (Silver Lake, Minnesota) |
| ABSTRACT | A variable operational mode transceiver device formed with an integrated circuit having a semiconductor material substrate supporting a feedback oscillator having a signal power divider electrically coupled to said feedback oscillator output, and a signal frequency multiplier electrically coupled to said signal power divider. A signal mixer has a pair of inputs of which one is electrically coupled to that remaining one of said pair of outputs of said signal power divider. |
| FILED | Wednesday, September 10, 2008 |
| APPL NO | 12/208198 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Telecommunications 455/75 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467949 | Kim |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kyusung Kim (Plymouth, Minnesota) |
| ASSIGNEE(S) | Honeywell International Inc. (Morristown, New Jersey) |
| INVENTOR(S) | Kyusung Kim (Plymouth, Minnesota) |
| ABSTRACT | Systems and methods for isolating a performance anomaly within one or more line replaceable units (LRUs) on a gas turbine engine by monitoring the start up transient are presented. The system comprises a set of sensors, an anomaly detector and a fault isolation reasoner. Each sensor of the set monitors at least one operating parameter of at least one engine component. The anomaly detector is configured to detect an anomaly in a component by comparing a particular value of an operating parameter to a base line value of that parameter. The specific cause of the startup anomaly is isolated utilizing a set of component reasoners that is based on the nature of the detected anomaly. The key events during the engine startup are identified by the combination of monitoring physically relevant phases of a startup and monitoring the engine control schedule. The values at these key events are used for comparing at the anomaly detector. |
| FILED | Friday, July 24, 2009 |
| APPL NO | 12/509155 |
| ART UNIT | 3667 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Vehicles, navigation, and relative location 71/100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08468041 | Vengerov |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Vengerov (Sunnyvale, California) |
| ASSIGNEE(S) | Oracle America, Inc. (Redwood Shores, California) |
| INVENTOR(S) | David Vengerov (Sunnyvale, California) |
| ABSTRACT | One embodiment of the present invention provides a system that allocates resources to projects in a computer system. During operation, the system determines a current demand by a project for a resource, and a current allocation of the resource to the project. The system also uses a computational model to compute an expected long-term utility of the project for the resource. Next, the system trades the resource between the project and other projects in the computer system to optimize expected long-term utilities. During this process, the system uses a reinforcement learning technique to update parameters of the computational model for the expected long-term utility of the project based on performance feedback. |
| FILED | Wednesday, December 22, 2004 |
| APPL NO | 11/021147 |
| ART UNIT | 3624 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data processing: Financial, business practice, management, or cost/price determination 75/7.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08468111 | Tgavalekos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nora T. Tgavalekos (Tewksbury, Massachusetts); Brian J. Scannell (Cambridge, Massachusetts); Elizabeth M. Begin (Billerica, Massachusetts); George C. Adams (Holliston, Massachusetts); Samuel H. Rosenthal (Lowell, Massachusetts); Seanna J. Gittler (Denver, Colorado); Eric Scheid (Wilmington, Massachusetts); Arthur B. Johnson (Andover, Massachusetts); Kenric P. Nelson (Hollis, New Hampshire) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Nora T. Tgavalekos (Tewksbury, Massachusetts); Brian J. Scannell (Cambridge, Massachusetts); Elizabeth M. Begin (Billerica, Massachusetts); George C. Adams (Holliston, Massachusetts); Samuel H. Rosenthal (Lowell, Massachusetts); Seanna J. Gittler (Denver, Colorado); Eric Scheid (Wilmington, Massachusetts); Arthur B. Johnson (Andover, Massachusetts); Kenric P. Nelson (Hollis, New Hampshire) |
| ABSTRACT | The technology described herein includes a system and/or a method for determining confidence of object identification. The technology includes selecting at least one confidence rule from a plurality of confidence rules based on a first discrimination identification and a second discrimination identification. The technology further includes generating an object confidence weight based on one or more first identification parameters, one or more second identification parameters, and the selected at least one confidence rule. The technology further includes fusing the received set of data based on an alpha parameter, a beta parameter, and the object confidence weight. The technology further includes generating a probability of identification of a classification of the object based on the fused data. |
| FILED | Tuesday, November 30, 2010 |
| APPL NO | 12/956515 |
| ART UNIT | 2129 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/45 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08468112 | de Kleer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Johan de Kleer (Los Altos, California); Sungwook Yoon (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Johan de Kleer (Los Altos, California); Sungwook Yoon (Palo Alto, California) |
| ABSTRACT | A system and method provides decision support for planning in an environment where a competition for use of resources exist and events affecting the planning are occurring dynamically. A system model of an actual system is provided. Then in a dynamic factored manner, an envisionment related to at least some aspects of the system model is built. From this envisionment output is generated related to at least some aspects of the system model. Finally, changes are made to the actual system, based on the generated output thereby changing a configuration and/or operation of the actual system. |
| FILED | Monday, March 22, 2010 |
| APPL NO | 12/728503 |
| ART UNIT | 2122 — AI & Simulation/Modeling |
| CURRENT CPC | Data processing: Artificial intelligence 76/46 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08468234 | Saxena |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tushar Saxena (Lexington, Massachusetts) |
| ASSIGNEE(S) | Verizon Corporate Services Group Inc. (Basking Ridge, New Jersey); Raytheon BBN Technologies Corp. (Cambridge, Massachusetts) |
| INVENTOR(S) | Tushar Saxena (Lexington, Massachusetts) |
| ABSTRACT | Disclosed are methods and systems that include presenting signals corresponding to a time-series of traffic on links of a network to a band-pass filter to obtain band-limited signals, the band pass filter centered substantially about a frequency corresponding to traffic to be tracked, determining coherence values of the band-limited signals, and, based on a comparison of the coherence values to a threshold, forming at least one map of the routing of the traffic based on the corresponding links. |
| FILED | Thursday, March 18, 2004 |
| APPL NO | 10/803508 |
| ART UNIT | 2456 — Computer Networks |
| CURRENT CPC | Electrical computers and digital processing systems: Multicomputer data transferring 79/224 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08468484 | Lilja |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Klas Olof Lilja (Dublin, California) |
| ASSIGNEE(S) | Klas Olof Lilja (Dublin, California) |
| INVENTOR(S) | Klas Olof Lilja (Dublin, California) |
| ABSTRACT | This invention comprises a layout method to effectively protect logic circuits against soft errors (non-destructive errors) and circuit cells, with layout, which are protected against soft errors. In particular, the method protects against cases where multiple nodes in circuit are affected by a single event. These events lead to multiple errors in the circuit, and while several methods exist to deal with single node errors, multiple node errors are very hard to deal with using any currently existing protection methods. The method is particularly useful for CMOS based logic circuits in modem technologies (.ltoreq.90 nm), where the occurrence of multiple node pulses becomes high (due to the high integration level). It uses a unique layout configuration, which makes the circuits protected against single event generated soft-errors. |
| FILED | Tuesday, March 20, 2012 |
| APPL NO | 13/425231 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Computer-aided design and analysis of circuits and semiconductor masks 716/119 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US RE44304 | Marks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tobin J. Marks (Evanston, Illinois); Antonio Facchetti (Chicago, Illinois); Hakan Usta (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Tobin J. Marks (Evanston, Illinois); Antonio Facchetti (Chicago, Illinois); Hakan Usta (Evanston, Illinois) |
| ABSTRACT | Disclosed are new conjugated compounds (e.g., monomers and polymers) that include ladder-type moieties which can be used for preparing semiconducting materials. Such conjugated compounds can exhibit high n-type carrier mobility and/or good current modulation characteristics. Compounds of the present teachings also can exhibit ambipolar semiconducting activity. In addition, the compounds of the present teachings can possess certain processing advantages such as solution-processability and/or good stability in ambient conditions. |
| FILED | Tuesday, February 14, 2012 |
| APPL NO | 13/396252 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Organic compounds 549/59 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Health and Human Services (HHS)
| US 08464713 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anatole D. Martin (Gainesville, Florida); Michael J. Banner (Alachua, Florida); Andrea Gabrielli (Gainesville, Florida); Neil Russell Euliano, II (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Anatole D. Martin (Gainesville, Florida); Michael J. Banner (Alachua, Florida); Andrea Gabrielli (Gainesville, Florida); Neil Russell Euliano, II (Gainesville, Florida) |
| ABSTRACT | A system and method for automated inspiratory muscle strength exercise includes software for setting a mechanical ventilator for a pressure regulated breath with an initial pressure target that is at the highest pressure setting a patient can tolerate and increasing the pressure target as tolerated. |
| FILED | Tuesday, July 24, 2012 |
| APPL NO | 13/556546 |
| ART UNIT | 3764 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Surgery 128/204.230 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465542 | Levy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert J. Levy (Merion Station, Pennsylvania); Ivan Alferiev (Clementon, New Jersey); Stanley J. Stachelek (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Robert J. Levy (Merion Station, Pennsylvania); Ivan Alferiev (Clementon, New Jersey); Stanley J. Stachelek (Philadelphia, Pennsylvania) |
| ABSTRACT | A modified polyurethane including a lipid substituent pendant from at least one urethane nitrogen and/or at least one carbon atom of the modified polyurethane, methods of preparing modified polyurethanes and the use thereof as an implantable biomaterial. |
| FILED | Monday, June 04, 2012 |
| APPL NO | 13/487984 |
| ART UNIT | 1763 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Prosthesis 623/2.420 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465694 | Lebl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michal Lebl (San Diego, California); Mark S. Chee (Encinitas, California); Steven M. Barnard (San Diego, California); David L. Heiner (San Diego, California); Vit Pokorny (Praha, Czech Republic); Mark J. Nibbe (San Diego, California); Aaron Christopher Jones (San Diego, California) |
| ASSIGNEE(S) | Illumina, Inc. (San Diego, California) |
| INVENTOR(S) | Michal Lebl (San Diego, California); Mark S. Chee (Encinitas, California); Steven M. Barnard (San Diego, California); David L. Heiner (San Diego, California); Vit Pokorny (Praha, Czech Republic); Mark J. Nibbe (San Diego, California); Aaron Christopher Jones (San Diego, California) |
| ABSTRACT | An apparatus for high-throughput combinatorial synthesis of organic molecules including a reaction vessel for containing a combinatorial chemistry synthetic reaction, a liquid dispenser for dispensing the liquid, a liquid aspirator and an adjustment mechanism. The reaction vessel includes an ingress aperture allowing a liquid to enter into an interior of the vessel and an egress aperture for aspirating the liquid from the vessel. The liquid dispenser dispenses liquid through the ingress aperture. The liquid aspirator aspirates liquid through the egress aperture and includes a rotor for carrying the vessel and orbiting the vessel about an axis of rotation. The rotor is oriented generally in a horizontal plane and includes an adjustment mechanism for adjusting the angle of the vessel relative to the horizontal plane in response to the centrifugal force generated by orbiting the vessel about the axis or rotation. A method of combinatorial synthesis of organic molecules is also disclosed. |
| FILED | Tuesday, February 08, 2011 |
| APPL NO | 13/023406 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/67 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465726 | Kung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hank F. Kung (Wynnewood, Pennsylvania); Mei-Ping Kung (Wynnewood, Pennsylvania); Zhi-Ping Zhuang (Lansdale, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Hank F. Kung (Wynnewood, Pennsylvania); Mei-Ping Kung (Wynnewood, Pennsylvania); Zhi-Ping Zhuang (Lansdale, Pennsylvania) |
| ABSTRACT | This invention relates to a method of imaging amyloid deposits and to labeled compounds, and methods of making labeled compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits. |
| FILED | Thursday, April 22, 2010 |
| APPL NO | 12/765397 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/1.890 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465727 | Bowser |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert P. Bowser (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Robert P. Bowser (Cranberry Township, Pennsylvania) |
| ABSTRACT | Methods for determining the onset of ALS in a subject are provided. One method includes analyzing a sample obtained from the subject for the presence or amount of one or more biomarkers indicative of ALS. In a preferred embodiment, the biomarkers are one or more of the following: C-reactive protein (CRP), cystatin c, plasminogen, complement C3, CysGly-transthyretin, and phosphorylated neurofilament heavy chain (pNFH). The sample is typically cerebral spinal fluid (CSF). The levels or concentrations of the biomarkers can be used to determine the onset of ALS, monitor the progression of ALS, or monitor the progression of a treatment for ALS. |
| FILED | Wednesday, October 06, 2010 |
| APPL NO | 12/899235 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/9.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465732 | Rafii et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shahin Rafii (New York, New York); Fan Zhang (Fort Lee, New Jersey); Marco Seandel (New York, New York) |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York); Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | Shahin Rafii (New York, New York); Fan Zhang (Fort Lee, New Jersey); Marco Seandel (New York, New York) |
| ABSTRACT | The present invention relates to adenovirus E4ORF 1 gene and to endothelial cells engineered to express the E40RF 1 gene. The present invention also relates to uses of the E40RF 1 gene, and cells expressing the E40RF1 gene, and to compositions comprising the E4ORF 1 gene, or comprising cells expressing the E4ORF 1 gene. |
| FILED | Friday, January 18, 2008 |
| APPL NO | 12/523372 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/93.210 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465737 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiaojiang Chen (Denver, Colorado); Vernon Michael Holers (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado (Denver, Colorado) |
| INVENTOR(S) | Xiaojiang Chen (Denver, Colorado); Vernon Michael Holers (Denver, Colorado) |
| ABSTRACT | Disclosed is a crystalline human CR2 protein in complex with C3d, and the three dimensional structure of the crystalline complex. Also disclosed are methods of use of the structure, particularly for structure-based identification of compounds that bind to CR2 and inhibit or enhance the binding of CR2 to a natural ligand, that bind to CR2 and agonize or antagonize the receptor, that bind to CR2 and inhibit or enhance CR2 dimerization, or that use the C3-binding ability of CR2 as a drug delivery vehicle. Also disclosed are therapeutic compounds obtained by such methods and uses for such compounds. |
| FILED | Thursday, April 12, 2007 |
| APPL NO | 11/786788 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465738 | Lyden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Lyden (New York, New York); Rosandra N. Kaplan (New York, New York); Rebecca D. Riba (New York, New York); Shahin Rafii (Great Neck, New York) |
| ASSIGNEE(S) | Cornell Research Foundation, Inc. (Ithaca, New York) |
| INVENTOR(S) | David Lyden (New York, New York); Rosandra N. Kaplan (New York, New York); Rebecca D. Riba (New York, New York); Shahin Rafii (Great Neck, New York) |
| ABSTRACT | The present invention is directed to a method of inhibiting tumor formation in a cancer patient at a site remote from sites of prior tumor formation and to a method of preventing metastases. These methods involve administering to the cancer patient an inhibitor of vascular endothelial growth factor receptor 1+ bone marrow-derived cells under conditions effective either to inhibit tumor formation in the cancer patient at a site remote from sites of prior tumor formation or to prevent metastases. Candidate compounds useful for such purposes can be screened depending on whether they bind to vascular endothelial growth factor receptor 1+ bone marrow-derived cells. Metastases in a cancer patient can be monitored by evaluating a patient sample for detection and quantification of vascular endothelial growth factor receptor 1+ bone marrow-derived cells and comparing the level of vascular endothelial growth factor receptor 1+ bone marrow-derived cells to prior levels. |
| FILED | Tuesday, September 22, 2009 |
| APPL NO | 12/564683 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/130.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465743 | Rosenberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven A. Rosenberg (Potomac, Maryland); Dhanalakshmi Chinnasamy (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Steven A. Rosenberg (Potomac, Maryland); Dhanalakshmi Chinnasamy (Rockville, Maryland) |
| ABSTRACT | The invention provides chimeric antigen receptors (CARs) comprising an antigen binding domain of a KDR-1121 or DC101 antibody, an extracellular hinge domain, a T cell receptor transmembrane domain, and an intracellular domain T cell receptor signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a host and methods of treating or preventing cancer in a host are also disclosed. |
| FILED | Tuesday, September 14, 2010 |
| APPL NO | 13/499349 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/134.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
08465746 — Compositions and methods for treatment, research and therapeutic applications for malaria
| US 08465746 | Haldar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kasturi Haldar (South Bend, Indiana); Pamela Tamez (South Bend, Indiana); Souvik Bhattacharjee (South Bend, Indiana) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Kasturi Haldar (South Bend, Indiana); Pamela Tamez (South Bend, Indiana); Souvik Bhattacharjee (South Bend, Indiana) |
| ABSTRACT | The present invention provides anti-Plasmodium immunogenic compositions comprising EVP1 (PFD0495c) or an antigenic portion thereof, as well as methods of immunizing against malaria employing these compositions. In other embodiments, the present invention provides methods of identifying Plasmodium infection employing agents that bind to EVP1 or an antibody generated thereto. |
| FILED | Wednesday, October 22, 2008 |
| APPL NO | 12/255902 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/184.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465749 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Che-Hung Robert Lee (Silver Spring, Maryland); Carl E. Frasch (Martinsburg, West Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Che-Hung Robert Lee (Silver Spring, Maryland); Carl E. Frasch (Martinsburg, West Virginia) |
| ABSTRACT | Methods for synthesis and manufacture of polysaccharide-protein conjugate vaccines at high yield are provided. The methods involve reaction of a hydrazide group on one reactant with an aldehyde or cyanate ester group on the other reactant. The reaction proceeds rapidly with a high conjugation efficiency, such that a simplified purification process can be employed to separate the conjugate product from the unconjugated protein and polysaccharide and other small molecule by-products. |
| FILED | Friday, September 23, 2011 |
| APPL NO | 13/243480 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/234.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465755 | Curtiss, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Roy Curtiss, III (Paradise Valley, Arizona); Melha Mellata (Tempe, Arizona); Bereket Zekarias (Mesa, Arizona); Zhaoxing Shi (Tempe, Arizona); Christine Branger (Phoenix, Arizona); Kenneth Roland (Mesa, Arizona) |
| ASSIGNEE(S) | The Arizona Board of Regents for and on Behalf of Arizona State University (Tempe, Arizona) |
| INVENTOR(S) | Roy Curtiss, III (Paradise Valley, Arizona); Melha Mellata (Tempe, Arizona); Bereket Zekarias (Mesa, Arizona); Zhaoxing Shi (Tempe, Arizona); Christine Branger (Phoenix, Arizona); Kenneth Roland (Mesa, Arizona) |
| ABSTRACT | The present invention relates to a recombinant bacterium that is capable of eliciting an immune response against at least two enteric pathogens, without substantially inducing an immune response specific to the serotype of the bacterium. The invention also relates to methods of making such a bacterium and vaccines and methods of using such a bacterium. |
| FILED | Monday, October 06, 2008 |
| APPL NO | 12/681721 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 424/258.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465916 | Bell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daphne Winifred Bell (Arlington, Massachusetts); Daniel A. Haber (Chestnut Hill, Massachusetts); Pasi Antero Janne (Newton, Massachusetts); Bruce E. Johnston (Brookline, Massachusetts); Thomas J. Lynch (Newton, Massachusetts); Matthew Meyerson (Concord, Massachusetts); Juan Guillermo Paez (Boston, Massachusetts); William R. Sellers (Chestnut Hill, Massachusetts); Jeffrey E. Settleman (Newton, Massachusetts); Raffaella Sordella (Bedford, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts); Dana Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Daphne Winifred Bell (Arlington, Massachusetts); Daniel A. Haber (Chestnut Hill, Massachusetts); Pasi Antero Janne (Newton, Massachusetts); Bruce E. Johnston (Brookline, Massachusetts); Thomas J. Lynch (Newton, Massachusetts); Matthew Meyerson (Concord, Massachusetts); Juan Guillermo Paez (Boston, Massachusetts); William R. Sellers (Chestnut Hill, Massachusetts); Jeffrey E. Settleman (Newton, Massachusetts); Raffaella Sordella (Bedford, Massachusetts) |
| ABSTRACT | The present invention is directed to a method for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) treatment. In a preferred embodiment, the presence of at least one variance in the kinase domain of the erbB1 gene confers sensitivity to the tyrosine kinase inhibitor gefitinib. Thus, a diagnostic assay for these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug. |
| FILED | Monday, August 20, 2007 |
| APPL NO | 11/894160 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465917 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xin Wei Wang (Rockville, Maryland); Junfang Ji (Clarksburg, Virginia); Taro Yamashita (Ishikawa, Japan); Carlo M. Croce (Columbus, Ohio) |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio); The United States of America, as represented by the Secretary of the Department of Health and Human Services, National Institutes of Health, Office of Technology Transfer (Washington, District of Columbia) |
| INVENTOR(S) | Xin Wei Wang (Rockville, Maryland); Junfang Ji (Clarksburg, Virginia); Taro Yamashita (Ishikawa, Japan); Carlo M. Croce (Columbus, Ohio) |
| ABSTRACT | The invention provides a method of determining an HCC subtype in a subject comprising a) obtaining a sample from the subject, b) assaying the sample to detect the expression of 1 or more biomarkers, and c) correlating the expression of the biomarkers with an HCC subtype in a subject. The invention further provides methods of detecting HCC stem cells in a sample. Additionally, the invention provides methods and compositions for treating subjects with HCC that take advantage of the biomarkers associated with HCC stem cells. |
| FILED | Monday, June 09, 2008 |
| APPL NO | 12/663586 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465923 | Saavedra et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Milene Saavedra (Denver, Colorado); Jerry Nick (Denver, Colorado) |
| ASSIGNEE(S) | National Jewish Health (Denver, Colorado) |
| INVENTOR(S) | Milene Saavedra (Denver, Colorado); Jerry Nick (Denver, Colorado) |
| ABSTRACT | The present invention is related to the novel discovery of a number of genes that were identified as systemic markers of pulmonary inflammation. This discovery allows for development of a novel tool for reliable, rapid and efficient assessment of therapeutic responses and enables design of novel therapies targeted against diseases associated with pulmonary inflammation. In one embodiment, the present invention allows quantification of therapeutic response in patients who have a disease associated with pulmonary inflammation. In preferred embodiments, the genes are CD64, ADAM9, CD36, IL32, HPSE, PLXND1, HCA 112, CSPG2, TLR2, and CD163. |
| FILED | Friday, December 16, 2011 |
| APPL NO | 13/328886 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465925 | Dapprich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Johannes Dapprich (Lawrenceville, New Jersey); Nancy Murphy (Downingtown, Pennsylvania); Christian Korfhage (Langenfeld, Germany) |
| ASSIGNEE(S) | Generation Biotech, LLC (Lawrenceville, New Jersey); GenoVision Inc. (West Chester, Pennsylvania); QIAGEN GmbH (Hilden, Germany) |
| INVENTOR(S) | Johannes Dapprich (Lawrenceville, New Jersey); Nancy Murphy (Downingtown, Pennsylvania); Christian Korfhage (Langenfeld, Germany) |
| ABSTRACT | The present invention provides methods and compositions for sequence-specific isolation of polynucleotide molecules from nucleic acid populations and subsequent amplification of isolated polynucleotide molecules or fragments thereof. |
| FILED | Friday, April 04, 2008 |
| APPL NO | 12/098197 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/6.120 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465960 | Kawaoka et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Shuji Hatakeyama (Tokyo, Japan) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Shuji Hatakeyama (Tokyo, Japan) |
| ABSTRACT | An isolated influenza B virus which has reduced sensitivity to one or more neuraminidase (NA) inhibitors, wherein the reduced sensitivity to one or more NA inhibitors is associated with a residue in NA other than Ile at position 222, a residue in NA other than Ser at a position 250, or a residue in NA other than Gly at position 402, as well as methods to detect such a virus or determine agents that inhibit the infection or replication of such as virus, are provided. |
| FILED | Friday, March 28, 2008 |
| APPL NO | 12/058389 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/235.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465983 | Lopez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gabriel P. Lopez (Albuquerque, New Mexico); Reema Zeineldin (Albuquerque, New Mexico); Menake E. Piyasena (South Pasadena, California); Sireesha Chemburu (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gabriel P. Lopez (Albuquerque, New Mexico); Reema Zeineldin (Albuquerque, New Mexico); Menake E. Piyasena (South Pasadena, California); Sireesha Chemburu (Albuquerque, New Mexico) |
| ABSTRACT | The invention relates to lipid bilayer coated beads and methods of using those beads in delivery systems, in immunoassays, in analytical assays and the like. |
| FILED | Monday, August 21, 2006 |
| APPL NO | 11/466046 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466110 | Dewhirst et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mark W. Dewhirst (Durham, North Carolina); Jonathan S. Stamler (Chapel Hill, North Carolina); Timothy J. McMahon (Durham, North Carolina); Pierre Sonveaux (Ottignies-Louvain-la-Neuve, Belgium) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Mark W. Dewhirst (Durham, North Carolina); Jonathan S. Stamler (Chapel Hill, North Carolina); Timothy J. McMahon (Durham, North Carolina); Pierre Sonveaux (Ottignies-Louvain-la-Neuve, Belgium) |
| ABSTRACT | The presently disclosed subject matter provides methods for increasing perfusion in hypoxic regions of tissues in subjects. Also provided are methods for treating diseases and/or disorders associated with hypoxia in subjects, methods for increasing sensitivity of tumors to radiation and/or chemotherapy treatments, methods for delaying tumor growth in subjects, and methods for inhibiting tumor blood vessel growth in subjects. In some embodiments, the presently disclosed methods involve administering to subjects in need thereof a first composition selected from the group consisting of a nitrosylated hemoglobin and an agent that induces nitrosylation of endogenous hemoglobin in the subject and a second composition comprising a hyperoxic gas. In some embodiments, the presently disclosed methods also include treating a tumor with radiation therapy, chemotherapy, photodynamic therapy, immunotherapy, or combinations thereof. Also provided are inhalable gases that can be employed in the presently disclosed methods. |
| FILED | Wednesday, April 18, 2012 |
| APPL NO | 13/449932 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/19.200 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466116 | Klinman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dennis M. Klinman (Potomac, Maryland); Takashi Sato (Yokohama, Japan) |
| ASSIGNEE(S) | The Unites States of America as represented by the Secretary of the Department of Health and Human Services (Washington, District of Columbia) |
| INVENTOR(S) | Dennis M. Klinman (Potomac, Maryland); Takashi Sato (Yokohama, Japan) |
| ABSTRACT | This disclosure provides a method of inducing epithelial cell growth. The method includes administering an effective amount of a K-type CpG oligonucleotide, thereby inducing epithelial cell growth. The epithelial cell can be in vivo or in vitro. Methods are also provided for inducing wound healing in a subject. The methods include administering to the subject a therapeutically effective amount of at least one K-type CpG ODN. |
| FILED | Friday, September 05, 2008 |
| APPL NO | 12/205756 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466118 | Banks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | William A. Banks (Saint Louis, Missouri); Vijaya B. Kumar (Saint Louis, Missouri); Thomas Darling (Saint Louis, Missouri); Robert Clayton (Foristell, Missouri) |
| ASSIGNEE(S) | Saint Louis University (St. Louis, Missouri) |
| INVENTOR(S) | William A. Banks (Saint Louis, Missouri); Vijaya B. Kumar (Saint Louis, Missouri); Thomas Darling (Saint Louis, Missouri); Robert Clayton (Foristell, Missouri) |
| ABSTRACT | There are disclosed agents that inhibit Blood Brain Barrier Proteins (BBBP). Such agents are useful in controlling agents entering and exiting the CNS. This allows for drugs to be more effective and/or allowing side effects of the drugs to be lowered. |
| FILED | Wednesday, April 23, 2008 |
| APPL NO | 12/597458 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466119 | Croce |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carlo M. Croce (Columbus, Ohio) |
| ASSIGNEE(S) | The Ohio State University Research Foundation (Columbus, Ohio) |
| INVENTOR(S) | Carlo M. Croce (Columbus, Ohio) |
| ABSTRACT | Methods for assessing a pathological condition in a subject include measuring one or more markers where a difference is indicative of acute lymphoblastic leukemia (ALL) or a predisposition to ALL, uses and compositions are disclosed. |
| FILED | Friday, August 22, 2008 |
| APPL NO | 12/674546 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44.A00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466121 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ta-Yuan Chang (Etna, New Hampshire); Catherine C. Y. Chang (Etna, New Hampshire) |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Ta-Yuan Chang (Etna, New Hampshire); Catherine C. Y. Chang (Etna, New Hampshire) |
| ABSTRACT | The present invention features methods for decreasing the size and density of amyloid plaques, decreasing cognitive decline associated with amyloid pathology, and treating Alzheimer's disease by selectively inhibiting the activity of Acyl-CoA:Cholesterol Acyltransferase 1, but not Acyl-CoA:Cholesterol Acyltransferase 2. |
| FILED | Monday, March 28, 2011 |
| APPL NO | 13/072915 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466123 | Gollin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Susanne M. Gollin (Pittsburgh, Pennsylvania); Rahul Atul Parikh (Pittsburgh, Pennsylvania); Xin Huang (Wexford, Pennsylvania) |
| ASSIGNEE(S) | Univeristy of Pittsburgh of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Susanne M. Gollin (Pittsburgh, Pennsylvania); Rahul Atul Parikh (Pittsburgh, Pennsylvania); Xin Huang (Wexford, Pennsylvania) |
| ABSTRACT | The present invention relates to the discovery that, in human cancer, an 11q deletion of ATM together with an increase in ATR and CHEK1 expression correlates with resistance to ionizing radiation which could be overcome by inhibition of the ATR/CHEK1 pathway. It provides for methods of identifying patients unlikely to exhibit an adequate response to radiation therapy and/or chemotherapy who may benefit from ATR/CHEK1 pathway inhibition, as well as methods of treating said patients. |
| FILED | Tuesday, February 28, 2012 |
| APPL NO | 13/407165 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466130 | Zarling et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David A. Zarling (Menlo Park, California); Hirak S. Basu (Madison, Wisconsin); Balaraman Kalyanaraman (Wauwatosa, Wisconsin); Joy Joseph (New Berlin, Wisconsin) |
| ASSIGNEE(S) | Colby Pharmaceutical Company (Menlo Park, California); Medical College of Wisconsin, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | David A. Zarling (Menlo Park, California); Hirak S. Basu (Madison, Wisconsin); Balaraman Kalyanaraman (Wauwatosa, Wisconsin); Joy Joseph (New Berlin, Wisconsin) |
| ABSTRACT | The inventions disclosed include methods of treating cancers and related neoplasias, especially prostate cancer, with pharmaceutically acceptable salts comprising lipophilic cation moieties linked to nitroxide or linked to hydroxylamine anti-oxidant groups. |
| FILED | Friday, September 04, 2009 |
| APPL NO | 12/554476 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/89 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466131 | Xie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiangqun Xie (Pittsburgh, Pennsylvania); Jianzhong Chen (Pittsburgh, Pennsylvania); Yuxun Zhang (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Xiangqun Xie (Pittsburgh, Pennsylvania); Jianzhong Chen (Pittsburgh, Pennsylvania); Yuxun Zhang (Pittsburgh, Pennsylvania) |
| ABSTRACT | A compound of Formula I: (I) has activity as a cannabinoid receptor antagonist. In Formula 1, R1 is unsubstituted or substituted aryl, unsubstituted or substituted cycloalkyl, unsubstituted or substituted heterocyclyl, unsubstituted or substituted aralkyl, or unsubstituted or substituted heteroaryl; R2 is unsubstituted or substituted alkyl, unsubstituted or substituted aryl, or unsubstituted or substituted heteroaryl; and R3 is unsubstituted or substituted alkyl, unsubstituted or substituted aralkyl, or unsubstituted or substituted heteroaralkyl; with the proviso that at least one of Ri and R3 is other than unsubstituted aralkyl or R2 is other than unsubstituted aryl. |
| FILED | Friday, October 31, 2008 |
| APPL NO | 12/740099 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/150 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466140 | Altieri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dario C. Altieri (Worcester, Massachusetts); Byoung Heon Kang (Shrewsbury, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Dario C. Altieri (Worcester, Massachusetts); Byoung Heon Kang (Shrewsbury, Massachusetts) |
| ABSTRACT | Described are mitochondria-targeted anti-tumor agents, and methods of making and using the same for the treatment of disorders associated with unwanted cell proliferation. |
| FILED | Wednesday, September 10, 2008 |
| APPL NO | 12/208207 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/183 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466142 | Gin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Gin (Pelham, New York); Jeremy Wilmot (Indianapolis, Indiana); Hakim Djaballah (Scarsdale, New York) |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | David Gin (Pelham, New York); Jeremy Wilmot (Indianapolis, Indiana); Hakim Djaballah (Scarsdale, New York) |
| ABSTRACT | The present invention provides novel cephalotaxus esters, syntheses thereof, and intermediates thereto. The invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of using said compounds or compositions in the treatment of proliferative diseases (e.g., benign neoplasm, cancer, inflammatory disease, autoimmune disease, diabetic retinopathy) and infectious disease. The invention further provides methods of using said compounds or compositions in the treatment of multidrug resistant cancer. |
| FILED | Tuesday, March 03, 2009 |
| APPL NO | 12/920227 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/214.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466154 | Fernandez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ariel Fernandez (Houston, Texas); William Bornmann (Missouri City, Texas); Gabriel Lopez-Berestein (Bellaire, Texas); Angela Sanguino (Pittsburgh, Pennsylvania); Zheng-Hong Peng (Missouri City, Texas); Anil K. Sood (Pearland, Texas) |
| ASSIGNEE(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Ariel Fernandez (Houston, Texas); William Bornmann (Missouri City, Texas); Gabriel Lopez-Berestein (Bellaire, Texas); Angela Sanguino (Pittsburgh, Pennsylvania); Zheng-Hong Peng (Missouri City, Texas); Anil K. Sood (Pearland, Texas) |
| ABSTRACT | This application describes a novel technology in drug discovery and drug-based imaging/detection: the wrapping technology. This technology is based on identified singularities in the structure of soluble proteins. In contrast with drug-design approaches based on standard structural considerations, the packing of a protein, or more precisely, its dehydron pattern, may be used as a selectivity filter to design small-molecule inhibitors. The wrapping technology described herein is a novel form of rational drug design for avoiding side effects in drug therapy and sharpening the inhibitory impact of drugs on the oncokinome. |
| FILED | Monday, October 29, 2007 |
| APPL NO | 11/927329 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/252.110 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466157 | Lawrence et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Harshani Lawrence (Tampa, Florida); Yiyu Ge (Tampa, Florida); Said M. Sebti (Tampa, Florida); Wayne Guida (St. Petersburg, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida); H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| INVENTOR(S) | Harshani Lawrence (Tampa, Florida); Yiyu Ge (Tampa, Florida); Said M. Sebti (Tampa, Florida); Wayne Guida (St. Petersburg, Florida) |
| ABSTRACT | Disclosed herein is the use of HLM-008182, as well as its analogues formed via in-house synthesis, as a potent proteasome inhibitors. A new method was developed for HLM-008182 through a four-step protocol and the method was further optimized to a two step protocol. The synthesis in both protocols was regioselective with TiCl4. The reaction was highly efficient with microwave assisted heating and THF as solvent. The modification around the molecule HLM-008182 established primary SAR, indicating that the proteasome inhibition activity was a function of the 2-side chain. |
| FILED | Tuesday, September 06, 2011 |
| APPL NO | 13/225976 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/253.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466177 | Luo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ming Luo (Birmingham, Alabama); Zhen Yang (Ridgewood, New Jersey) |
| ASSIGNEE(S) | The UAB Research Foundation (Birmingham, Alabama) |
| INVENTOR(S) | Ming Luo (Birmingham, Alabama); Zhen Yang (Ridgewood, New Jersey) |
| ABSTRACT | Compounds that are useful in treating or preventing viral infections, such as influenza, are described herein. Further described are compositions made from these compounds and methods for using the compounds and their compositions in treating or preventing viral infections. |
| FILED | Friday, October 31, 2008 |
| APPL NO | 12/682341 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/342 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466183 | Roberts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Edward Roberts (La Jolla, California); Hugh Rosen (La Jolla, California); Steven Brown (San Diego, California); Miguel A. Guerrero (La Jolla, California); Xuemei Peng (La Jolla, California); Ramulu Poddutoori (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Edward Roberts (La Jolla, California); Hugh Rosen (La Jolla, California); Steven Brown (San Diego, California); Miguel A. Guerrero (La Jolla, California); Xuemei Peng (La Jolla, California); Ramulu Poddutoori (La Jolla, California) |
| ABSTRACT | Compounds of the following generic structure are provided: Such compounds activate a sphingosine-I-phosphate receptor of the subtype 1 (S1P1), and have utility in the treatment of malconditions mediated by S1P1 activation. More specifically, such compounds are beneficial in the treatment of, for example, multiple sclerosis, transplant rejection and/or adult respiratory syndrome. |
| FILED | Thursday, September 06, 2012 |
| APPL NO | 13/605427 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/364 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466185 | Berggren et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Per-Olof Berggren (Miami, Florida); Alejandro Caicedo (Midland, Florida); Over Cabrera (Miami, Florida) |
| ASSIGNEE(S) | BioCrine AB (Solna, Sweden) |
| INVENTOR(S) | Per-Olof Berggren (Miami, Florida); Alejandro Caicedo (Midland, Florida); Over Cabrera (Miami, Florida) |
| ABSTRACT | Methods for regulating glucagon release and of treating hypoglycemia, and for screening drug candidates for treating hypoglycemia. The methods are useful for treating diabetes mellitus and screening drug candidates for potential efficacy. |
| FILED | Thursday, March 12, 2009 |
| APPL NO | 12/921483 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/380 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466195 | Maher et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Pamela A. Maher (La Jolla, California); David R. Schubert (La Jolla, California) |
| ASSIGNEE(S) | Salk Institute for Biological Studies (La Jolla, California) |
| INVENTOR(S) | Pamela A. Maher (La Jolla, California); David R. Schubert (La Jolla, California) |
| ABSTRACT | Disclosed herein, inter alia, are methods and compositions for treating a complication of diabetes or a vascular disease using a 5-desoxy-flavone and/or 5-desoxy-flavonol. |
| FILED | Monday, March 15, 2010 |
| APPL NO | 13/255192 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/456 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466203 | Paik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Choohyun Paik (Cheltenham, Pennsylvania); Stephen Lewis Trokel (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Choohyun Paik (Cheltenham, Pennsylvania); Stephen Lewis Trokel (New York, New York) |
| ABSTRACT | A method for stabilizing collagenous eye tissues by nitrite and nitroalcohol treatment. The topical stiffening agent contains sodium nitrite or a nitroalcohol in a buffered balanced salt solution and can be applied to the surface of the eye on a daily basis for a prolonged period. Application of the solution results in progressive stabilization of the corneal and scleral tissues through non-enzymatic cross-linking of collagen fibers. The compounds can penetrate into the corneal stroma without the need to remove the corneal epithelium. In addition, ultraviolet light is not needed to activate the cross-linking process. The resulting stabilization of corneal and scleral tissues can prevent future alterations in corneal curvature and has utility in diseases such as keratoconus, keratectasia, progressive myopia, and glaucoma. |
| FILED | Thursday, December 06, 2007 |
| APPL NO | 12/517382 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/727 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466263 | Marasco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wayne A. Marasco (Wellesley, Massachusetts); Agnes Lo (Boston, Massachusetts); Chen Xu (Beijing, China PRC) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Wayne A. Marasco (Wellesley, Massachusetts); Agnes Lo (Boston, Massachusetts); Chen Xu (Beijing, China PRC) |
| ABSTRACT | The invention provides scFv antibodies and monoclonal antibodies that bind to and decrease an activity of Carbonic Anhydrase IX (G250). Also provided are methods of treating and/or preventing cancer, such as renal clear cell cancer. Also provided are methods of identifying a carbonic anhydrase IX (G250) protein. The invention additionally provides methods of modifying immune effector cells, and the immune effector cells modified thereby. |
| FILED | Monday, December 04, 2006 |
| APPL NO | 12/095773 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Chemistry: Natural resins or derivatives; peptides or proteins; lignins or reaction products thereof 530/388.260 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466311 | Lipton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Stuart A. Lipton (La Jolla, California); Takumi Satoh (La Jolla, California) |
| ASSIGNEE(S) | Sanford-Burnham Medical Research Institute (La Jolla, California) |
| INVENTOR(S) | Stuart A. Lipton (La Jolla, California); Takumi Satoh (La Jolla, California) |
| ABSTRACT | Neurite outgrowth-promoting prostaglandins (NEPPs) and other electrophilic compounds bind to Keap1, a negative regulator of the transcription factor Nrf2, and prevent Keap1-mediated inactivation of Nrf2 and, thus, enhance Nrf2 translocation into the nucleus of neuronal cells. Therefore, neuroprotective compositions and related methods are provided that employ such neuroprotective compounds, and prodrugs of such compounds, to cause dissociation of Nrf2 from a Keap1/Nrf2 complex. |
| FILED | Monday, September 19, 2011 |
| APPL NO | 13/236579 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Organic compounds 562/403 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467875 | Bennett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Maria E Bennett (Lyndhurst, Ohio); Julie Grill (Chapel Hill, North Carolina); Tina E Lechman (Chagrin Falls, Ohio); Joseph J Mrva (Euclid, Ohio); Jonathan L Sakai (Fairview Park, Ohio); Robert B Strother (Willoughby Hills, Ohio); Geoffrey B Thrope (Shaker Heights, Ohio); Therese M Zmina (Willoughby, Ohio) |
| ASSIGNEE(S) | Medtronic, Inc. (Minneapolis, Minnesota) |
| INVENTOR(S) | Maria E Bennett (Lyndhurst, Ohio); Julie Grill (Chapel Hill, North Carolina); Tina E Lechman (Chagrin Falls, Ohio); Joseph J Mrva (Euclid, Ohio); Jonathan L Sakai (Fairview Park, Ohio); Robert B Strother (Willoughby Hills, Ohio); Geoffrey B Thrope (Shaker Heights, Ohio); Therese M Zmina (Willoughby, Ohio) |
| ABSTRACT | Systems and methods treat urologic dysfunctions by implanting a lead and electrode in a tissue region affecting urologic function, and implanting a pulse generator in an anterior pelvic region remote from the electrode. Bilateral stimulation of the left and/or right branches of the dorsal genital nerves using a single lead implanted in adipose or other tissue in the region at or near the pubic symphysis is able to treat urinary incontinence. |
| FILED | Wednesday, March 28, 2007 |
| APPL NO | 11/729333 |
| ART UNIT | 3766 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery: Light, thermal, and electrical application 67/41 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 08465200 | Sun |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jiangang Sun (Westmont, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Jiangang Sun (Westmont, Illinois) |
| ABSTRACT | A computer-implemented method, apparatus, and computer program product implement enhanced thermal tomography three-dimensional (3D) thermal effusivity imaging. Experimental thermal imaging data is acquired. A response function is derived and a convolution formulation is constructed from the experimental thermal imaging data. A deconvolution solution procedure is implemented that includes constructing a matrix solution equation with a damping parameter, and solving the matrix solution equation with a selected number of iterations to construct a plurality of effusivity images. Using the novel depth deconvolution algorithm with experimental data acquired from a one-sided pulsed thermal-imaging system provides greater sensitivity for internal sample features substantially eliminating degradation in depth resolution. |
| FILED | Friday, June 04, 2010 |
| APPL NO | 12/793829 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Thermal measuring and testing 374/44 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465715 | Cordaro |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph G. Cordaro (Oakland, California) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Joseph G. Cordaro (Oakland, California) |
| ABSTRACT | The present invention describes the synthesis of a family of metal bis(borano) hypophosphite complexes. One procedure described in detail is the syntheses of complexes beginning from phosphorus trichloride and sodium borohydride. Temperature, solvent, concentration, and atmosphere are all critical to ensure product formation. In the case of sodium bis(borano) hypophosphite, hydrogen gas was evolved upon heating at temperatures above 150° C. Included in this family of materials are the salts of the alkali metals Li, Na and K, and those of the alkaline earth metals Mg and Ca. Hydrogen storage materials are possible. In particular the lithium salt, Li[PH2(BH3)2], theoretically would contain nearly 12 wt % hydrogen. Analytical data for product characterization and thermal properties are given. |
| FILED | Friday, July 02, 2010 |
| APPL NO | 12/829592 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemistry of inorganic compounds 423/287 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465797 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fanglin Chen (Irmo, South Carolina); Chenghao Yang (Columbia, South Carolina); Chao Jin (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Fanglin Chen (Irmo, South Carolina); Chenghao Yang (Columbia, South Carolina); Chao Jin (Columbia, South Carolina) |
| ABSTRACT | In accordance with the present disclosure, a method for fabricating a solid oxide fuel cell is described. The method includes forming an asymmetric porous ceramic tube by using a phase inversion process. The method further includes forming an asymmetric porous ceramic layer on a surface of the asymmetric porous ceramic tube by using a phase inversion process. The tube is co-sintered to form a structure having a first porous layer, a second porous layer, and a dense layer positioned therebetween. |
| FILED | Tuesday, January 18, 2011 |
| APPL NO | 13/008081 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating processes 427/115 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465883 | Balsara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nitash Pervez Balsara (El Cerrito, California); Moon Jeong Park (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Nitash Pervez Balsara (El Cerrito, California); Moon Jeong Park (Berkeley, California) |
| ABSTRACT | Polymers having an improved ability to entrain water are characterized, in some embodiments, by unusual humidity-induced phase transitions. The described polymers (e.g., hydrophilically functionalized block copolymers) have a disordered state and one or more ordered states (e.g., a lamellar state, a gyroid state, etc.). In one aspect, the polymers are capable of undergoing a disorder-to-order transition while the polymer is exposed to an increasing temperature at a constant relative humidity. In some aspects the polymer includes a plurality of portions, wherein a first portion forms proton-conductive channels within the membrane and wherein the channels have a width of less than about 6 nm. The described polymers are capable of entraining and preserving water at high temperature and low humidity. Surprisingly, in some embodiments, the polymers are capable of entraining greater amounts of water with the increase of temperature. The polymers can be used in Polymer Electrolyte Membranes in fuel cells. |
| FILED | Monday, June 30, 2008 |
| APPL NO | 12/667219 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemistry: Electrical current producing apparatus, product, and process 429/493 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465949 | Duan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Junxin Duan (Beijing, China PRC); Lan Tang (Beijing, China PRC); Ye Liu (Beijing, China PRC); Wenping Wu (Beijing, China PRC); Jason Quinlan (Albany, California); Randall Kramer (Lincoln, California) |
| ASSIGNEE(S) | Novozymes, Inc (Davis, California); Novozymes A/S (Bagsvaerd, Denmark) |
| INVENTOR(S) | Junxin Duan (Beijing, China PRC); Lan Tang (Beijing, China PRC); Ye Liu (Beijing, China PRC); Wenping Wu (Beijing, China PRC); Jason Quinlan (Albany, California); Randall Kramer (Lincoln, California) |
| ABSTRACT | The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Friday, July 13, 2012 |
| APPL NO | 13/548718 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/69.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465953 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Youngnyun Kim (Oakland, California); Keelnatham Shanmugam (Gainesville, Florida); Lonnie O. Ingram (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Youngnyun Kim (Oakland, California); Keelnatham Shanmugam (Gainesville, Florida); Lonnie O. Ingram (Gainesville, Florida) |
| ABSTRACT | Non-recombinant bacteria that produce ethanol as the primary fermentation product, associated nucleic acids and polypeptides, methods for producing ethanol using the bacteria, and kits are disclosed. |
| FILED | Thursday, April 26, 2007 |
| APPL NO | 12/298216 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/161 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465958 | Lopez de Leon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alfredo Lopez de Leon (Davis, California); Michael Rey (Davis, California) |
| ASSIGNEE(S) | Novozymes A/S (Bagsvaerd, Denmark) |
| INVENTOR(S) | Alfredo Lopez de Leon (Davis, California); Michael Rey (Davis, California) |
| ABSTRACT | The present invention relates to isolated polypeptides having endoglucanase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. |
| FILED | Thursday, August 30, 2012 |
| APPL NO | 13/600071 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/209 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465961 | Caimi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Perry G Caimi (Kennett Square, Pennsylvania); Mark Emptage (Wilmington, Delaware); Xu Li (Newark, Delaware); Paul V Viitanen (West Chester, Pennsylvania); Yat-Chen Chou (Lakewood, Colorado); Mary Ann Franden (Centennial, Colorado); Min Zhang (Lakewood, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy LLC (, None); E I du Pont de Nemours and Company (Wilmington, Delaware) |
| INVENTOR(S) | Perry G Caimi (Kennett Square, Pennsylvania); Mark Emptage (Wilmington, Delaware); Xu Li (Newark, Delaware); Paul V Viitanen (West Chester, Pennsylvania); Yat-Chen Chou (Lakewood, Colorado); Mary Ann Franden (Centennial, Colorado); Min Zhang (Lakewood, Colorado) |
| ABSTRACT | Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol. |
| FILED | Tuesday, July 03, 2012 |
| APPL NO | 13/540641 |
| ART UNIT | 1657 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/252.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466004 | Peumans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter Peumans (Palo Alto, California); Soichi Uchida (Yokohama, Japan); Stephen R. Forrest (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Peter Peumans (Palo Alto, California); Soichi Uchida (Yokohama, Japan); Stephen R. Forrest (Ann Arbor, Michigan) |
| ABSTRACT | Organic photosensitive optoelectronic devices are disclosed. The devises are thin-film crystalline organic optoelectronic devices capable of generating a voltage when exposed to light, and prepared by a method including the steps of: depositing a first organic layer over a first electrode; depositing a second organic layer over the first organic layer; depositing a confining layer over the second organic layer to form a stack; annealing the stack; and finally depositing a second electrode over the second organic layer. |
| FILED | Monday, October 05, 2009 |
| APPL NO | 12/573795 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/99 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466011 | Blum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yigal D. Blum (San Jose, California); William Siu-Keung Chu (Newark, California); David Brent MacQueen (Foster City, California); Yijian Shi (Mountain View, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Yigal D. Blum (San Jose, California); William Siu-Keung Chu (Newark, California); David Brent MacQueen (Foster City, California); Yijian Shi (Mountain View, California) |
| ABSTRACT | The disclosure provides methods and materials suitable for use as encapsulation barriers in electronic devices. In one embodiment, for example, there is provided an electroluminescent device or other electronic device encapsulated by alternating layers of a silicon-containing bonding material and a ceramic material. The encapsulation methods provide, for example, electronic devices with increased stability and shelf-life. The invention is useful, for example, in the field of microelectronic devices. |
| FILED | Wednesday, March 04, 2009 |
| APPL NO | 13/202062 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor device manufacturing: Process 438/127 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466207 | Whinnery, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Leroy L. Whinnery, Jr. (Danville, California); Steven H. Goods (Livermore, California); Dawn M. Skala (Fremont, California); Craig C. Henderson (Falls Church, Virginia); Patrick N. Keifer (Livermore, California) |
| ASSIGNEE(S) | Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Leroy L. Whinnery, Jr. (Danville, California); Steven H. Goods (Livermore, California); Dawn M. Skala (Fremont, California); Craig C. Henderson (Falls Church, Virginia); Patrick N. Keifer (Livermore, California) |
| ABSTRACT | Disclosed is a method for making a polyurethane closed-cell foam material exhibiting a bulk density below 4 lbs/ft3 and high strength. The present embodiment uses the reaction product of a modified MDI and a sucrose/glycerine based polyether polyol resin wherein a small measured quantity of the polyol resin is “pre-reacted” with a larger quantity of the isocyanate in a defined ratio such that when the necessary remaining quantity of the polyol resin is added to the “pre-reacted” resin together with a tertiary amine catalyst and water as a blowing agent, the polymerization proceeds slowly enough to provide a stable foam body. |
| FILED | Tuesday, February 27, 2007 |
| APPL NO | 11/712283 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Synthetic resins or natural rubbers 521/159 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466429 | Guethlein |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gary Guethlein (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Gary Guethlein (Livermore, California) |
| ABSTRACT | Methods and devices enable coupling of a charged particle beam to a radio frequency quadrupole accelerator. Coupling of the charged particle beam is accomplished, at least in-part, by relying on of sensitivity of the input phase space acceptance of the radio frequency quadrupole to the angle of the input charged particle beam. A first electric field across a beam deflector deflects the particle beam at an angle that is beyond the acceptance angle of the radio frequency quadrupole. By momentarily reversing or reducing the established electric field, a narrow portion of the charged particle beam is deflected at an angle within the acceptance angle of the radio frequency quadrupole. In another configuration, beam is directed at an angle within the acceptance angle of the radio frequency quadrupole by the first electric field and is deflected beyond the acceptance angle of the radio frequency quadrupole due to the second electric field. |
| FILED | Wednesday, October 05, 2011 |
| APPL NO | 13/253944 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Radiant energy 250/396.R00 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466447 | Branz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Howard M. Branz (Golden, Colorado); Charles Teplin (Golden, Colorado); Pauls Stradins (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Howard M. Branz (Golden, Colorado); Charles Teplin (Golden, Colorado); Pauls Stradins (Golden, Colorado) |
| ABSTRACT | A crystal oriented metal back contact for solar cells is disclosed herein. In one embodiment, a photovoltaic device and methods for making the photovoltaic device are disclosed. The photovoltaic device includes a metal substrate with a crystalline orientation and a heteroepitaxial crystal silicon layer having the same crystal orientation of the metal substrate. A heteroepitaxial buffer layer having the crystal orientation of the metal substrate is positioned between the substrate and the crystal silicon layer to reduce diffusion of metal from the metal foil into the crystal silicon layer and provide chemical compatibility with the heteroepitaxial crystal silicon layer. Additionally, the buffer layer includes one or more electrically conductive pathways to electrically couple the crystal silicon layer and the metal substrate. |
| FILED | Thursday, August 06, 2009 |
| APPL NO | 12/537152 |
| ART UNIT | 2811 — Semiconductors/Memory |
| CURRENT CPC | Active solid-state devices 257/9 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466589 | Alexander et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James Pellegrino Alexander (Niskayuna, New York); Ayman Mohamed Fawzi El-Refaie (Niskayuna, New York); Xiaochun Shen (Niskayuna, New York) |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | James Pellegrino Alexander (Niskayuna, New York); Ayman Mohamed Fawzi El-Refaie (Niskayuna, New York); Xiaochun Shen (Niskayuna, New York) |
| ABSTRACT | The present application provides a stator. The stator may include a number of poles and a stator tip and cooling assembly. The stator tip and cooling assembly may include a number of stator tips with a number of cooling tubes adjacent thereto such that the stator tips align with the poles and the cooling tubes cool the poles. |
| FILED | Thursday, September 23, 2010 |
| APPL NO | 12/888463 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Electrical generator or motor structure 310/59 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466658 | Kajouke |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lateef A. Kajouke (San Pedro, California) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Lateef A. Kajouke (San Pedro, California) |
| ABSTRACT | Systems and methods are provided for bi-directional energy delivery. A charging system comprises a first bi-directional conversion module, a second bi-directional conversion module, and an isolation module coupled between the first bi-directional conversion module and the second bi-directional conversion module. The isolation module provides galvanic isolation between the first bi-directional conversion module and the second bi-directional conversion module. |
| FILED | Wednesday, August 05, 2009 |
| APPL NO | 12/535975 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Electricity: Battery or capacitor charging or discharging 320/128 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467197 | Perisic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Milun Perisic (Torrance, California); Ray M. Ransom (Big Bear City, California); Lateef A. Kajouke (San Pedro, California) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan) |
| INVENTOR(S) | Milun Perisic (Torrance, California); Ray M. Ransom (Big Bear City, California); Lateef A. Kajouke (San Pedro, California) |
| ABSTRACT | Systems and methods are provided for delivering energy from an input interface to an output interface. An electrical system includes an input interface, an output interface, an energy conversion module coupled between the input interface and the output interface, and a control module. The control module determines a duty cycle control value for operating the energy conversion module to produce a desired voltage at the output interface. The control module determines an input power error at the input interface and adjusts the duty cycle control value in a manner that is influenced by the input power error, resulting in a compensated duty cycle control value. The control module operates switching elements of the energy conversion module to deliver energy to the output interface with a duty cycle that is influenced by the compensated duty cycle control value. |
| FILED | Monday, November 08, 2010 |
| APPL NO | 12/941552 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Electric power conversion systems 363/17 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467425 | Zhang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shukui Zhang (Yorktown, Virginia) |
| ASSIGNEE(S) | Jefferson Science Associates, LLC (Newport News, Virginia) |
| INVENTOR(S) | Shukui Zhang (Yorktown, Virginia) |
| ABSTRACT | A method for obtaining high-energy, high repetition rate laser pulses simultaneously using continuous wave (CW) amplifiers is described. The method provides for generating micro-joule level energy in pico-second laser pulses at Mega-hertz repetition rates. |
| FILED | Monday, November 28, 2011 |
| APPL NO | 13/373716 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Coherent light generators 372/25 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467971 | Zemla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Adam T. Zemla (Brentwood, California); Carol E. Zhou (Pleasanton, California); Jason R. Smith (Mountain House, California); Marisa W. Lam (Pleasanton, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Adam T. Zemla (Brentwood, California); Carol E. Zhou (Pleasanton, California); Jason R. Smith (Mountain House, California); Marisa W. Lam (Pleasanton, California) |
| ABSTRACT | Disclosed are computational methods of clustering a set of protein structures based on local and pair-wise global similarity values. Pair-wise local and global similarity values are generated based on pair-wise structural alignments for each protein in the set of protein structures. Initially, the protein structures are clustered based on pair-wise local similarity values. The protein structures are then clustered based on pair-wise global similarity values. For each given cluster both a representative structure and spans of conserved residues are identified. The representative protein structure is used to assign newly-solved protein structures to a group. The spans are used to characterize conservation and assign a “structural footprint” to the cluster. |
| FILED | Tuesday, August 07, 2007 |
| APPL NO | 11/890863 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467984 | Gering |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kevin L. Gering (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Kevin L. Gering (Idaho Falls, Idaho) |
| ABSTRACT | A system includes an electrochemical cell, monitoring hardware, and a computing system. The monitoring hardware periodically samples charge characteristics of the electrochemical cell. The computing system periodically determines cell information from the charge characteristics of the electrochemical cell. The computing system also periodically adds a first degradation characteristic from the cell information to a first sigmoid expression, periodically adds a second degradation characteristic from the cell information to a second sigmoid expression and combines the first sigmoid expression and the second sigmoid expression to develop or augment a multiple sigmoid model (MSM) of the electrochemical cell. The MSM may be used to estimate a capacity loss of the electrochemical cell at a desired point in time and analyze other characteristics of the electrochemical cell. The first and second degradation characteristics may be loss of active host sites and loss of free lithium for Li-ion cells. |
| FILED | Wednesday, September 30, 2009 |
| APPL NO | 12/571253 |
| ART UNIT | 2857 — Printing/Measuring and Testing |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/63 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08468275 | Salapura et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Valentina Salapura (Yorktown Heights, New York); Robert W. Wisniewski (Yorktown Heights, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Valentina Salapura (Yorktown Heights, New York); Robert W. Wisniewski (Yorktown Heights, New York) |
| ABSTRACT | Hardware support for software controlled reconfiguration of performance counters may include a plurality of performance counters collecting one or more counts of one or more selected activities. A storage element stores data value representing a time interval, and a timer element reads the data value and detects expiration of the time interval based on the data value and generates a signal. A plurality of configuration registers stores a set of performance counter configurations. A state machine receives the signal and selects a configuration register from the plurality of configuration registers for reconfiguring the one or more performance counters. |
| FILED | Friday, January 08, 2010 |
| APPL NO | 12/684496 |
| ART UNIT | 2181 — Computer Architecture and I/O |
| CURRENT CPC | Electrical computers and digital data processing systems: Input/output 710/10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08468416 | Gara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alan G. Gara (Mount Kisco, New York); Dong Chen (Croton on Hudson, New York); Philip Heidelberger (Cortlandt Manor, New York); Martin Ohmacht (Yorktown Heights, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Alan G. Gara (Mount Kisco, New York); Dong Chen (Croton on Hudson, New York); Philip Heidelberger (Cortlandt Manor, New York); Martin Ohmacht (Yorktown Heights, New York) |
| ABSTRACT | A method and system are disclosed for providing combined error code protection and subgroup parity protection for a given group of n bits. The method comprises the steps of identifying a number, m, of redundant bits for said error protection; and constructing a matrix P, wherein multiplying said given group of n bits with P produces m redundant error correction code (ECC) protection bits, and two columns of P provide parity protection for subgroups of said given group of n bits. In the preferred embodiment of the invention, the matrix P is constructed by generating permutations of m bit wide vectors with three or more, but an odd number of, elements with value one and the other elements with value zero; and assigning said vectors to rows of the matrix P. |
| FILED | Tuesday, June 26, 2007 |
| APPL NO | 11/768527 |
| ART UNIT | 2112 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Error detection/correction and fault detection/recovery 714/758 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08468611 | Riedo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elisa Riedo (Atlanta, Georgia); Seth R. Marder (Atlanta, Georgia); Walt A. de Heer (Atlanta, Georgia); Robert J. Szoskiewicz (Manhattan, Kansas); Vamsi K. Kodali (Visakhapatnam, India); Simon C. Jones (Los Angeles, California); Takashi Okada (Mie, Japan); Debin Wang (Atlanta, Georgia); Jennifer E. Curtis (Atlanta, Georgia); Clifford L. Henderson (Douglasville, Georgia); Yueming Hua (Sunnyvale, California) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Elisa Riedo (Atlanta, Georgia); Seth R. Marder (Atlanta, Georgia); Walt A. de Heer (Atlanta, Georgia); Robert J. Szoskiewicz (Manhattan, Kansas); Vamsi K. Kodali (Visakhapatnam, India); Simon C. Jones (Los Angeles, California); Takashi Okada (Mie, Japan); Debin Wang (Atlanta, Georgia); Jennifer E. Curtis (Atlanta, Georgia); Clifford L. Henderson (Douglasville, Georgia); Yueming Hua (Sunnyvale, California) |
| ABSTRACT | Improved nanolithography components, systems, and methods are described herein. The systems and methods generally employ a resistively heated atomic force microscope tip to thermally induce a chemical change in a surface. In addition, certain polymeric compositions are also disclosed. |
| FILED | Tuesday, June 01, 2010 |
| APPL NO | 12/791466 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM] 850/33 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
08464926 — Method of friction stir welding dissimilar metals and workpiece assemblies formed thereby
| US 08464926 | Kou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sindo Kou (Madison, Wisconsin); Vahid Firouzdor (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Sindo Kou (Madison, Wisconsin); Vahid Firouzdor (Madison, Wisconsin) |
| ABSTRACT | In a process for friction stir welding together pieces of dissimilar material, a first piece of a second metal is overlaid onto a first piece of a first metal that is dissimilar from the second metal such that at least a portion of the first piece of second metal overlaps a portion of the first piece of first metal. A second piece of the first metal is placed in side-to-side relationship with the first piece of second metal and overlies another portion of the first piece of first metal. The relative arrangement between the second piece of first metal and the first piece of second metal define a joint line overlying the first piece of first metal. The first piece of first metal, the first piece of second metal, and the second piece of first metal are friction stir welded together along the joint line. |
| FILED | Friday, October 30, 2009 |
| APPL NO | 12/589948 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Metal fusion bonding 228/112.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465655 | Sun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hongwei Sun (Lexington, Massachusetts); Sai Liu (Columbia, Missouri) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Hongwei Sun (Lexington, Massachusetts); Sai Liu (Columbia, Missouri) |
| ABSTRACT | A fabrication method for forming polymer nanopillars using an anodic aluminum oxide (AAO) membrane and an imprint process. A substrate is cleaned and a water soluble tape is applied to the substrate to define a coating area. The substrate is spin-coated with a polymer solution and an AAO membrane is placed on top of the coated area on the substrate and turned over whereby a silicon wafer is attached onto the AAO membrane forming an AAO membrane assembly, which is pressed in an imprintor. Then, the AAO membrane assembly is removed from the imprintor, it is disassembled, and the AAO membrane is dissolved in a NaOH solution forming a polymer substrate with nanopillars. |
| FILED | Tuesday, March 06, 2012 |
| APPL NO | 13/413358 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Etching a substrate: Processes 216/11 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465706 | Attinger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Daniel Attinger (New York, New York); Jie Xu (New York, New York) |
| ASSIGNEE(S) | Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Daniel Attinger (New York, New York); Jie Xu (New York, New York) |
| ABSTRACT | Microfluidic systems and methods can dispense single or multiple fluid particles (such as a gas or other fluid bubble) or an encapsulated particle (e.g., a bead or biological cell) into a microchannel. |
| FILED | Friday, December 18, 2009 |
| APPL NO | 12/642434 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing 422/505 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465967 | Woehl et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jorg C. Woehl (Bayside, Wisconsin); Christine A. Carlson (Brown Deer, Wisconsin) |
| ASSIGNEE(S) | UWM Research Foundation, Inc. (Milwaukee, Wisconsin) |
| INVENTOR(S) | Jorg C. Woehl (Bayside, Wisconsin); Christine A. Carlson (Brown Deer, Wisconsin) |
| ABSTRACT | A method of trapping a charged particle. The method includes providing a planar substrate having a conductive surface thereon, the conductive surface having at least one non-conductive region. The method also includes applying a solution to the conductive surface, the solution comprising at least one charged particle. The method further includes applying a voltage of a threshold level to the conductive surface. The method also includes, in response to the voltage, generating an electrostatic field in the solution adjacent to a boundary between the conductive surface and the non-conductive region. The method also includes setting the threshold level of voltage to result in a strength of the electrostatic field sufficient to prevent the particle from crossing the electrostatic field. |
| FILED | Friday, January 21, 2011 |
| APPL NO | 13/011413 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemistry: Molecular biology and microbiology 435/283.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465983 | Lopez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gabriel P. Lopez (Albuquerque, New Mexico); Reema Zeineldin (Albuquerque, New Mexico); Menake E. Piyasena (South Pasadena, California); Sireesha Chemburu (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gabriel P. Lopez (Albuquerque, New Mexico); Reema Zeineldin (Albuquerque, New Mexico); Menake E. Piyasena (South Pasadena, California); Sireesha Chemburu (Albuquerque, New Mexico) |
| ABSTRACT | The invention relates to lipid bilayer coated beads and methods of using those beads in delivery systems, in immunoassays, in analytical assays and the like. |
| FILED | Monday, August 21, 2006 |
| APPL NO | 11/466046 |
| ART UNIT | 1641 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466142 | Gin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | David Gin (Pelham, New York); Jeremy Wilmot (Indianapolis, Indiana); Hakim Djaballah (Scarsdale, New York) |
| ASSIGNEE(S) | Sloan-Kettering Institute for Cancer Research (New York, New York) |
| INVENTOR(S) | David Gin (Pelham, New York); Jeremy Wilmot (Indianapolis, Indiana); Hakim Djaballah (Scarsdale, New York) |
| ABSTRACT | The present invention provides novel cephalotaxus esters, syntheses thereof, and intermediates thereto. The invention also provides pharmaceutical compositions comprising a compound of the present invention and methods of using said compounds or compositions in the treatment of proliferative diseases (e.g., benign neoplasm, cancer, inflammatory disease, autoimmune disease, diabetic retinopathy) and infectious disease. The invention further provides methods of using said compounds or compositions in the treatment of multidrug resistant cancer. |
| FILED | Tuesday, March 03, 2009 |
| APPL NO | 12/920227 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Drug, bio-affecting and body treating compositions 514/214.10 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467054 | Swalwell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jarred E. Swalwell (Shoreline, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Jarred E. Swalwell (Shoreline, Washington) |
| ABSTRACT | A sheathless flow cytometry system is disclosed wherein a fluid containing particles of interest, for example cells, flows through a sensing region, and is illuminated in the sensing region with one or more light source. Light resulting from the interaction of the particles with the illumination is received by an objective, and focused toward a field stop having an aperture comprising relatively large end portions and a relatively small center portion. Light deflectors, such as prisms, are disposed over the relatively large end portions of the aperture. The system is arranged such that light from particles in focus in the sensing region is focused on the relatively small center portion of the aperture. Peripheral detectors are positioned to receive light from the light deflectors, and a scatter detector is positioned to receive light passing through the center portion. The detector signals may be used to identify which of the detector signals correspond to particles in focus as they passed through the sensing region. |
| FILED | Friday, January 22, 2010 |
| APPL NO | 13/145772 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/343 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467269 | Zhou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shengli Zhou (Mansfield, Connecticut); Peter Willett (Coventry, Connecticut); Christian Berger (Pittsburgh, Pennsylvania); Sean Mason (Nashua, New Jersey) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Shengli Zhou (Mansfield, Connecticut); Peter Willett (Coventry, Connecticut); Christian Berger (Pittsburgh, Pennsylvania); Sean Mason (Nashua, New Jersey) |
| ABSTRACT | Advantageous online and/or real-time OFDM-based underwater acoustic (UWA) apparatus, systems and methods are provided according to the present disclosure. The apparatus, systems and methods employ a receiver with a bank of parallel branches, with each branch having a self-correlator matched to a different waveform scaling factor. A detection is declared when any of the branches leads to a correlation metric larger than a pre-defined threshold. The branch with the largest metric yields a Doppler scale estimate and a coarse synchronization point. The proposed apparatus, systems and methods use one OFDM preamble, thereby avoiding the need to buffer the whole data packet before data demodulation and enabling online and/or real-time operation. Thus, the disclosed apparatus, systems and methods are advantageously applicable to UWA communications. |
| FILED | Thursday, April 01, 2010 |
| APPL NO | 12/752239 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications, electrical: Acoustic wave systems and devices 367/134 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467867 | Gianchandani et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yogesh B. Gianchandani (Ann Arbor, Michigan); Tao Li (Ann Arbor, Michigan); Roma Y. Gianchandani (Ann Arbor, Michigan) |
| ASSIGNEE(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| INVENTOR(S) | Yogesh B. Gianchandani (Ann Arbor, Michigan); Tao Li (Ann Arbor, Michigan); Roma Y. Gianchandani (Ann Arbor, Michigan) |
| ABSTRACT | A sensor is mounted to a needle at a location proximate to a tip of the needle. The sensor senses tissue density of tissue in contact with the tip as the needle passes through the tissue. Further, the sensor detects a change in tissue density as the tip passes from one tissue to a target tissue. |
| FILED | Monday, April 18, 2011 |
| APPL NO | 13/088673 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Surgery 6/547 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467975 | Ryan T. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Gill Ryan T. (Denver, Colorado); Michael D. Lynch (Boulder, Colorado); Tanya E. W. Lipscomb (Boulder, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a Body Corporate (Denver, Colorado) |
| INVENTOR(S) | Gill Ryan T. (Denver, Colorado); Michael D. Lynch (Boulder, Colorado); Tanya E. W. Lipscomb (Boulder, Colorado) |
| ABSTRACT | The present disclosure concerns methods and compositions relating to mixed-library parallel gene trait mapping. In particular embodiments, the methods concern quantitative microarray hybridization techniques for genome-wide identification of trait conferring genes. In other embodiments, the compositions concern genetic elements that confer or are associated with a trait. In an exemplary embodiment, the trait is enhanced growth rate. In another exemplary embodiment, genetic elements that confer enhanced bacterial growth rate comprise part or all of the sequences of SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4 or SEQ ID NO:5. In other embodiments, the genetic elements that confer enhanced bacterial growth rate correspond to the YliF, adrA, yeaP, yddV or ydeH genes of E. coli. |
| FILED | Monday, July 04, 2011 |
| APPL NO | 13/175929 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Data processing: Measuring, calibrating, or testing 72/19 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08468611 | Riedo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elisa Riedo (Atlanta, Georgia); Seth R. Marder (Atlanta, Georgia); Walt A. de Heer (Atlanta, Georgia); Robert J. Szoskiewicz (Manhattan, Kansas); Vamsi K. Kodali (Visakhapatnam, India); Simon C. Jones (Los Angeles, California); Takashi Okada (Mie, Japan); Debin Wang (Atlanta, Georgia); Jennifer E. Curtis (Atlanta, Georgia); Clifford L. Henderson (Douglasville, Georgia); Yueming Hua (Sunnyvale, California) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Elisa Riedo (Atlanta, Georgia); Seth R. Marder (Atlanta, Georgia); Walt A. de Heer (Atlanta, Georgia); Robert J. Szoskiewicz (Manhattan, Kansas); Vamsi K. Kodali (Visakhapatnam, India); Simon C. Jones (Los Angeles, California); Takashi Okada (Mie, Japan); Debin Wang (Atlanta, Georgia); Jennifer E. Curtis (Atlanta, Georgia); Clifford L. Henderson (Douglasville, Georgia); Yueming Hua (Sunnyvale, California) |
| ABSTRACT | Improved nanolithography components, systems, and methods are described herein. The systems and methods generally employ a resistively heated atomic force microscope tip to thermally induce a chemical change in a surface. In addition, certain polymeric compositions are also disclosed. |
| FILED | Tuesday, June 01, 2010 |
| APPL NO | 12/791466 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Scanning-probe techniques or apparatus; applications of scanning-probe techniques, e.g., Scanning probe microscopy [SPM] 850/33 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 08465562 | Schubert |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Peter J. Schubert (Naperville, Illinois) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Peter J. Schubert (Naperville, Illinois) |
| ABSTRACT | A system and method capable of efficient production of synthesis gas from biomass materials in a manner which can be scaled to relatively large throughput capacities. the system is operable to compact a loose biomass material and simultaneously introduce the compacted biomass material into entrances of internal passages of multiple parallel reactors, heat the compacted biomass material within the reactors to a temperature at which organic molecules within the compacted biomass material break down to form ash and gases comprising carbon monoxide and hydrogen gases, inhibit combustion of the compacted biomass material when heated within the internal passages of the reactors, conduct the carbon monoxide and hydrogen gases through the reactors in a direction opposite the movement of the compacted biomass through the reactors, and remove the ash from the reactor. |
| FILED | Wednesday, April 14, 2010 |
| APPL NO | 12/760241 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Gas: Heating and illuminating 048/61 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08465683 | Hagen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tim Hagen (Superior, Wisconsin); George J. Coy (Mantorville, Minnesota); Matthew Coy (Mantorville, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (St. Paul, Minnesota); Clean Plus, Inc. (Concord, Minnesota) |
| INVENTOR(S) | Tim Hagen (Superior, Wisconsin); George J. Coy (Mantorville, Minnesota); Matthew Coy (Mantorville, Minnesota) |
| ABSTRACT | This disclosure describes a method and apparatus for agglomerating stover to produce a liquid absorbing particle. The method comprises providing stover particles coated with a first binder component and then rolling the stover particles coated with the first binder component on a rotating surface. The rotating surface is inclined sufficiently to aid in the rolling of the stover particles. A second liquid binder component that readily chemically crosslinks with the first binder component is applied to the first binder component to produce a web that the stover particles adhere to. The web in combination with the inclined rotating surface rolls the stover particles thereby forming an agglomerated stover particle that will be suitable for absorbing liquids. Agglomerated stover particles are also described. |
| FILED | Monday, August 22, 2011 |
| APPL NO | 13/214761 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Plastic and nonmetallic article shaping or treating: Processes 264/117 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467052 | Chao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Kuanglin Chao (Ellicott City, Maryland); Moon S. Kim (Silver Spring, Maryland); Alan M. Lefcourt (Elkridge, Maryland); David Tuschel (Monroeville, Pennsylvania); Oksana Olkhovyk (Pittsburgh, Pennsylvania); Yongliang Liu (Laurel, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Kuanglin Chao (Ellicott City, Maryland); Moon S. Kim (Silver Spring, Maryland); Alan M. Lefcourt (Elkridge, Maryland); David Tuschel (Monroeville, Pennsylvania); Oksana Olkhovyk (Pittsburgh, Pennsylvania); Yongliang Liu (Laurel, Maryland) |
| ABSTRACT | System and method for determining the presence of a contaminant in a sample using Raman spectroscopic data. The sample may be food or feed and the contaminant may be melamine. The sample is illuminated with substantially monochromatic light to produce Raman scattered photons. The Raman scattered photons are collected to generate Raman spectroscopic data. The Raman spectroscopic data may comprise at least one of a Raman spectrum and a spatially accurate wavelength resolved Raman image. The Raman spectroscopic data is analyzed to determine the presence or absence of a contaminant in a sample. The concentration of the contaminant in the sample can also be determined by using a ratio algorithm. |
| FILED | Friday, November 06, 2009 |
| APPL NO | 12/614000 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Optics: Measuring and testing 356/301 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 08464750 | Richard et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | James A. Richard (Grant, Alabama); Herman L. Pickens (Gurley, Alabama) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | James A. Richard (Grant, Alabama); Herman L. Pickens (Gurley, Alabama) |
| ABSTRACT | A magnetostrictive pressure regulating system includes a magnetostrictive valve that incorporates a magnetostrictive actuator with at least one current-carrying coil disposed thereabout. A pressure force sensor, in fluid communication with the fluid exiting the valve, includes (i) a magnetostrictive material, (ii) a magnetic field generator in proximity to the magnetostrictive material for inducing a magnetic field in and surrounding the magnetostrictive material wherein lines of magnetic flux passing through the magnetostrictive material are defined, and (iii) a sensor positioned adjacent to the magnetostrictive material and in the magnetic field for measuring changes in at least one of flux angle and flux density when the magnetostrictive material experiences an applied force that is aligned with the lines of magnetic flux. The pressure of the fluid exiting the valve causes the applied force. A controller coupled to the sensor and to the current-carrying coil adjusts a current supplied to the current-carrying coil based on the changes so-measured. |
| FILED | Wednesday, June 30, 2010 |
| APPL NO | 12/826887 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Fluid handling 137/487.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08466776 | Fink et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Patrick W. Fink (Missouri City, Texas); Timothy F. Kennedy (Houston, Texas); Gregory Y. Lin (Friendswood, Texas) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Patrick W. Fink (Missouri City, Texas); Timothy F. Kennedy (Houston, Texas); Gregory Y. Lin (Friendswood, Texas) |
| ABSTRACT | A passive wireless tag assembly comprises a plurality of antennas and transmission lines interconnected with circuitry and constructed and arranged in a Van Atta array or configuration to reflect an interrogator signal in the direction from where it came. The circuitry may comprise at least one surface acoustic wave (SAW)-based circuit that functions as a signal reflector and is operatively connected with an information circuit. In another embodiment, at least one delay circuit and/or at least one passive modulation circuit(s) are utilized. In yet another embodiment, antennas connected to SAW-based devices are mounted to at least one of the orthogonal surfaces of a corner reflector. |
| FILED | Thursday, July 01, 2010 |
| APPL NO | 12/828558 |
| ART UNIT | 2684 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Communications: Electrical 340/10.400 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467903 | Ihrke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chris A. Ihrke (Hartland, Michigan); David M. Reich (Huntsville, Alabama); Lyndon Bridgwater (Houston, Texas); Douglas Martin Linn (White Lake, Michigan); Scott R. Askew (Houston, Texas); Myron A. Diftler (Houston, Texas); Robert Platt (Houston, Texas); Brian Hargrave (Dickenson, Texas); Michael C. Valvo (League City, Texas); Muhammad E. Abdallah (Houston, Texas); Frank Noble Permenter (Webster, Texas); Joshua S. Mehling (League City, Texas) |
| ASSIGNEE(S) | GM Global Technology Operations LLC (Detroit, Michigan); The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Chris A. Ihrke (Hartland, Michigan); David M. Reich (Huntsville, Alabama); Lyndon Bridgwater (Houston, Texas); Douglas Martin Linn (White Lake, Michigan); Scott R. Askew (Houston, Texas); Myron A. Diftler (Houston, Texas); Robert Platt (Houston, Texas); Brian Hargrave (Dickenson, Texas); Michael C. Valvo (League City, Texas); Muhammad E. Abdallah (Houston, Texas); Frank Noble Permenter (Webster, Texas); Joshua S. Mehling (League City, Texas) |
| ABSTRACT | A humanoid robot includes a robotic hand having at least one finger. An actuation system for the robotic finger includes an actuator assembly which is supported by the robot and is spaced apart from the finger. A tendon extends from the actuator assembly to the at least one finger and ends in a tendon terminator. The actuator assembly is operable to actuate the tendon to move the tendon terminator and, thus, the finger. |
| FILED | Tuesday, September 22, 2009 |
| APPL NO | 12/564086 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Data processing: Generic control systems or specific applications 7/258 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 08465795 | Lujan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rene Lujan (Sunnyvale, California); William S. Wong (San Carlos, California); Julia Rosolovsky Greer (Pasadena, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Rene Lujan (Sunnyvale, California); William S. Wong (San Carlos, California); Julia Rosolovsky Greer (Pasadena, California) |
| ABSTRACT | A method of forming a thin-film layered electronic device over a flexible substrate comprises the steps of depositing a buffer layer over the flexible substrate, heating the substrate and buffer layer stack to a temperature at which plastic deformation of the buffer layer takes place, cooling the stack, then forming the thin-film electronic device over the plastically deformed buffer layer without further plastic deformation of the buffer layer. The heating and cooling to cause plastic deformation of the buffer layer is referred to as annealing. The thin-film electronic device is formed by a process according to which all steps are performed at a temperature below that at which further plastic deformation of the buffer layer occurs. In-process strain and runout are reduced, improving device yield on flexible substrates. An optional metal base layer may be formed over the buffer layer prior annealing. |
| FILED | Tuesday, May 20, 2008 |
| APPL NO | 12/123732 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Coating processes 427/97.100 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467273 | Eliezer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oren E. Eliezer (Plano, Texas) |
| ASSIGNEE(S) | XW LLC (Dallas, Texas) |
| INVENTOR(S) | Oren E. Eliezer (Plano, Texas) |
| ABSTRACT | A novel and useful system and method for leap second and daylight saving time (DST) correction for use in a radio controlled clock (RCC) receiver. The RCC receiver extracts schedule information from the frame, including the time for the DST transition and whether a leap second needs to be added at the end of this half-year. Linear error correcting coding is used for the leap second and the DST on/off indications, while non-linear error correcting coding (e.g., a look up table) is used for the DST schedule to enhance reception reliability in the presence of noise and interference. The one second/one hour corrections are scheduled to occur when they should take place and the correction is applied exactly when DST or leap second is to go into effect, without having to receive anything around the time of the correction. |
| FILED | Tuesday, March 20, 2012 |
| APPL NO | 13/424807 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Horology: Time measuring systems or devices 368/47 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 08467273 | Eliezer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oren E. Eliezer (Plano, Texas) |
| ASSIGNEE(S) | XW LLC (Dallas, Texas) |
| INVENTOR(S) | Oren E. Eliezer (Plano, Texas) |
| ABSTRACT | A novel and useful system and method for leap second and daylight saving time (DST) correction for use in a radio controlled clock (RCC) receiver. The RCC receiver extracts schedule information from the frame, including the time for the DST transition and whether a leap second needs to be added at the end of this half-year. Linear error correcting coding is used for the leap second and the DST on/off indications, while non-linear error correcting coding (e.g., a look up table) is used for the DST schedule to enhance reception reliability in the presence of noise and interference. The one second/one hour corrections are scheduled to occur when they should take place and the correction is applied exactly when DST or leap second is to go into effect, without having to receive anything around the time of the correction. |
| FILED | Tuesday, March 20, 2012 |
| APPL NO | 13/424807 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Horology: Time measuring systems or devices 368/47 |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 08467739 | Vajha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sasidhar Vajha (Brooklyn Park, Minnesota); Timothy T. Childs (Minnetonka, Minnesota); Daniel C. Eller (Silver Lake, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sasidhar Vajha (Brooklyn Park, Minnesota); Timothy T. Childs (Minnetonka, Minnesota); Daniel C. Eller (Silver Lake, Minnesota) |
| ABSTRACT | A variable operational mode transceiver device formed with an integrated circuit having a semiconductor material substrate supporting a feedback oscillator having a signal power divider electrically coupled to said feedback oscillator output, and a signal frequency multiplier electrically coupled to said signal power divider. A signal mixer has a pair of inputs of which one is electrically coupled to that remaining one of said pair of outputs of said signal power divider. |
| FILED | Wednesday, September 10, 2008 |
| APPL NO | 12/208198 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Telecommunications 455/75 |
| VIEW PATENT | @ USPTO: Full Text PDF |
European Union (EU)
| US 08466834 | Fortuny-Guasch |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joaquim Fortuny-Guasch (Taino, Italy) |
| ASSIGNEE(S) | The European Union, Represented by the European Commission (, Belgium) |
| INVENTOR(S) | Joaquim Fortuny-Guasch (Taino, Italy) |
| ABSTRACT | A method of radar-imaging a scene in the far-field of a one-dimensional radar array, comprises providing an array of backscatter data D(fm, x′n) of the scene, these backscatter data being associated to a plurality of positions x′n, n=0 . . . N−1, N>1, that are regularly spaced along an axis of the radar array. The backscatter data for each radar array position x′n are sampled in frequency domain, at different frequencies fm, m=0 . . . M−1, M>1, defined by fm=fc−B/2+m−Δf, where fc represents the center frequency, B the bandwidth and Δf the frequency step of the sampling. A radar reflectivity image 1 (αm′, βn′) is computed in a pseudo-polar coordinate system based upon the formula (2) with formula (3) where j represents the imaginary unit, formula (A) is the baseband frequency, FFT2D denotes the 2D Fast Fourier Transform operator, αm′, m′=0 . . . M−1, and βn′, n′=0 . . . N−1 represent a regular grid in the pseudo-polar coordinate system, and Pmax is chosen >0 depending on a predefined accuracy to be achieved. A corresponding method of radar-imaging a scene in the far-field of a two-dimensional radar array is also proposed. |
| FILED | Monday, May 04, 2009 |
| APPL NO | 12/992767 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Communications: Directive radio wave systems and devices 342/179 |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 08465295 | Taskovics et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven M. Taskovics (Framingham, Massachusetts); Brett H. Kobelin (Billerica, Massachusetts); Marc S. Pepi (Sudbury, Massachusetts); Steven R. Mitchell (Danville, New Hampshire) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Steven M. Taskovics (Framingham, Massachusetts); Brett H. Kobelin (Billerica, Massachusetts); Marc S. Pepi (Sudbury, Massachusetts); Steven R. Mitchell (Danville, New Hampshire) |
| ABSTRACT | A fluid percussion system for modeling penetrating brain injury includes a fluid percussion device that takes inputs in the form of pressurized gas and electrical signals from a computer and outputs a single hydraulic pulse, or multiple hydraulic pulses in quick succession. The fluid percussion device may include a pneumatic cylinder assembly and a hydraulic cylinder assembly that is actuated by the pneumatic cylinder assembly to produce the hydraulic pulse(s) of pressurized fluid. Each pulse may be used to rapidly inflate and deflate an attached balloon (representing a brain penetrating device). The balloon may be inserted in a test specimen, and the rapid inflation and deflation of the balloon creates a lesion that simulates a penetrating brain injury. A calibration system that employs an optical sensor may be used to determine maximum balloon diameter achieved during rapid inflation. |
| FILED | Wednesday, February 06, 2008 |
| APPL NO | 12/027142 |
| ART UNIT | 3711 — Amusement and Education Devices |
| CURRENT CPC | Education and demonstration 434/270 |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 08466274 | Tang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hengli Tang (Tallahassee, Florida) |
| ASSIGNEE(S) | Florida State University Research Foundation (Tallahassee, Florida) |
| INVENTOR(S) | Hengli Tang (Tallahassee, Florida) |
| ABSTRACT | Small interfering RNAs (siRNAs) or small hairpin RNA (shRNAs) and compositions comprising same are provided that target human cyclophilin A (CyPA) to inhibit Hepatitis C (HCV) infection. Such siRNA and shRNAs may have a length of from about 19 to about 29 contiguous nucleotides corresponding to a specific region of human cyclophilin A (CyPA) cDNA of from about nucleotide 155 to about nucleotide 183 having particular potency against CyPA and HCV. Such siRNA and shRNAs may be formulated as naked compositions or pharmaceutical compositions. DNA polynucleotides, plasmids, and viral or non-viral vectors are also provided that encode siRNA or shRNA molecules, which may be delivered directly to cells or in combination with delivery agents, such as lipids, polymers, encapsulated lipid particles, such as liposomes. Methods for treating, managing inhibiting, preventing, etc., HCV infection using such siRNA and shRNAs and compositions comprising same are also provided. |
| FILED | Tuesday, October 02, 2012 |
| APPL NO | 13/633199 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Organic compounds 536/24.500 |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, June 18, 2013.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2013/fedinvent-patents-20130618.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page