FedInvent™ Patents
Patent Details for Tuesday, February 21, 2017
This page was updated on Monday, March 27, 2023 at 05:09 AM GMT
Department of Health and Human Services (HHS)
| US 09572340 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| INVENTOR(S) | Raphael C Lee (Chicago, Illinois); Annie Kuo (Salt Lake City, Utah); Hanne Gissel Hyldkrog (Trige, Denmark); Florin Despa (North Riverside, Illinois); Devkumar Mustafi (Chicago, Illinois) |
| ABSTRACT | Compounds and methods for refolding of proteins in an aqueous solution. In particular, biocompatible multiblock copolymer surfactants such as poloxamers, meroxapols, poloxamines, or polyols are used to catalyze proper refolding without changing the protein composition, and restore the protein to its native conformation and native biological function. The methods can be practiced both in vivo and in vitro. The biocompatible multiblock copolymer surfactants can be used for renaturation of recombinantly expressed proteins, and for renaturation of proteins that are unfolded due to heat, irradiation, mechanical shearing, electrical shock, frostbite, chemical stress, and other abiotic or biotic stresses. |
| FILED | Monday, August 04, 2014 |
| APPL NO | 14/450760 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0226 (20130101) Original (OR) Class Peptides C07K 1/1136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572506 | Schmidt et al. |
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| APPLICANT(S) | Robert N. Schmidt (Cleveland, Ohio); Frederick J. Lisy (Euclid, Ohio); Gerard G. Skebe (Eastlake, Ohio); Troy S. Prince (Cleveland Heights, Ohio) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Robert N. Schmidt (Cleveland, Ohio); Frederick J. Lisy (Euclid, Ohio); Gerard G. Skebe (Eastlake, Ohio); Troy S. Prince (Cleveland Heights, Ohio) |
| ABSTRACT | The present invention relates to a physiological recording electrode, a method, and apparatus for attaching the physiological electrode to a subject. The physiological electrode comprises a substrate having an upper and a lower surface, and at least one penetrator(s) protruding from the upper surface of the substrate. The penetrator(s) is capable of piercing through the stratum corneum or outer layer of the skin, and transmitting an electric potential from the lower layers of the epidermis through the penetrator(s) which can be measured, or detecting agents from the lower layers of the epidermis primarily the stratum germinativum layer. At least one epidermis stop may be provided resulting in the formation of detritus troughs interposed between adjacent penetrator(s) and epidermis stops. The physiological electrode is attached to a subject by means of the apparatus and method for attaching same. The present invention also includes a method of sensing biopotentials in the skin. |
| FILED | Wednesday, December 15, 2010 |
| APPL NO | 12/968496 |
| ART UNIT | 3739 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0408 (20130101) Original (OR) Class A61B 5/0478 (20130101) A61B 5/0492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572514 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yi Wang (New York, New York); He Zhu (Timonium, Maryland) |
| ASSIGNEE(S) | Martin R. Prince (New York, New York) |
| INVENTOR(S) | Yi Wang (New York, New York); He Zhu (Timonium, Maryland) |
| ABSTRACT | A method for producing multiple temporal frames of a time-resolved contrast enhanced magnetic resonance angiogram from a subject using an MR contrast agent by repeatedly applying RF pulses and sampling data in the corresponding image k-space along spiral trajectories that start at the k-space center and spiral outward toward the k-space edge. |
| FILED | Monday, August 13, 2012 |
| APPL NO | 13/584367 |
| ART UNIT | 3768 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/561 (20130101) G01R 33/4824 (20130101) G01R 33/5602 (20130101) G01R 33/5607 (20130101) G01R 33/5614 (20130101) G01R 33/5635 (20130101) G01R 33/5676 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572788 | King et al. |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Randall King (Newton, Massachusetts); Xing Zeng (Brookline, Massachusetts); Katharine L. Sackton (Somerville, Massachusetts) |
| ABSTRACT | The disclosure provides compositions and methods for treating cell cycle disorders. Compositions of the disclosure include proTAME, a prodrug analog of TAME and apcin, the combination of which inhibits an activity or function of the anaphase promoting complex (APC) by a synergistic mechanism. |
| FILED | Tuesday, May 13, 2014 |
| APPL NO | 14/276994 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/27 (20130101) Original (OR) Class A61K 31/27 (20130101) A61K 31/138 (20130101) A61K 31/138 (20130101) A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/555 (20130101) A61K 31/555 (20130101) A61K 31/4196 (20130101) A61K 31/4196 (20130101) A61K 45/06 (20130101) A61K 47/48038 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1001 (20130101) A61N 2005/109 (20130101) A61N 2005/1021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572789 | Lin et al. |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Hening Lin (Ithaca, New York); Bin He (Ithaca, New York) |
| ABSTRACT | The instant application describes novel compounds that modulate (in particular, inhibit) Sirt2, with structures according to Formulas (1) and (2) provided herein. The invention is also directed to pharmaceutical compositions thereof, methods of treatment (i.e., cancer and neurodegenerative disease) by administration of the modulating compounds, assay methods for finding modulators of Sirt2, and kits for practicing the assay method. |
| FILED | Friday, June 03, 2016 |
| APPL NO | 15/172756 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/27 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572793 | Faller et al. |
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| APPLICANT(S) | Douglas V. Faller (Weston, Massachusetts); Robert M. Williams (Fort Collins, Colorado) |
| ASSIGNEE(S) | Faller and Williams Technology, LLC (Fort Collins, Colorado) |
| INVENTOR(S) | Douglas V. Faller (Weston, Massachusetts); Robert M. Williams (Fort Collins, Colorado) |
| ABSTRACT | The invention is directed to compounds that are specific inhibitors of PKC delta, and methods and compositions for the treatment and prevention of cancers and other disorders. Compositions comprising compounds of the invention are used to treat cancers such as, for example, carcinoid and neuroendocrine tumors, malignant melanomas, pancreatic, gastrointestinal and lung cancers. Neuroendocrine tumor cell lines of pulmonary and gastrointestinal origin are surprisingly sensitive to PKC delta inhibition by the compounds of the invention. The invention is further directed to methods, compositions and kits containing compounds of the formulas (Ia), (IIa), (IIIa), (IVa), and (V) as disclosed and described in FIGS. 11 and 12. |
| FILED | Friday, May 06, 2016 |
| APPL NO | 15/148420 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/403 (20130101) Original (OR) Class A61K 31/404 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 209/86 (20130101) C07D 405/06 (20130101) C07D 487/14 (20130101) Enzymes C12Y 207/10002 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 2333/91205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572794 | Hamm et al. |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Heidi E. Hamm (Nashville, Tennessee); Shaun R. Stauffer (Nashville, Tennessee); Craig W. Lindsley (Brentwood, Tennessee); Wandong Wen (Nashville, Tennessee); Summer E. Young (Nashville, Tennessee); Matthew T. Duvernay (Nashville, Tennessee); Kayla J. Temple (Antioch, Tennessee) |
| ABSTRACT | Embodiments of the invention include substituted indole compounds and compositions thereof to inhibit protease activated receptor-4. Also described are methods of preparation of compositions and methods for treating diseases related to thrombotic disorders by administration of the composition. |
| FILED | Thursday, August 06, 2015 |
| APPL NO | 14/820488 |
| ART UNIT | 1672 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/407 (20130101) Original (OR) Class A61K 31/437 (20130101) A61K 31/519 (20130101) A61K 31/4985 (20130101) A61K 31/5025 (20130101) Heterocyclic Compounds C07D 209/10 (20130101) C07D 209/30 (20130101) C07D 221/00 (20130101) C07D 237/00 (20130101) C07D 239/00 (20130101) C07D 401/04 (20130101) C07D 513/04 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/42 (20130101) C08K 5/42 (20130101) Compositions of Macromolecular Compounds C08L 67/02 (20130101) C08L 67/02 (20130101) C08L 67/02 (20130101) C08L 69/00 (20130101) C08L 69/00 (20130101) C08L 69/00 (20130101) C08L 2205/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572815 | Zuo et al. |
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| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Jian Zuo (Memphis, Tennessee); Taosheng Chen (Germantown, Tennessee); Brandon Walters (Memphis, Tennessee); Bryan Kuo (Memphis, Tennessee); Bradley Walters (Memphis, Tennessee) |
| ABSTRACT | In one aspect, the invention relates to pharmaceutical compositions comprising agents that activate the expression of Atoh1, or pharmaceutically acceptable salts, solvates, or polymorphs thereof; and agents that inhibit the expression of p27Kip1, or pharmaceutically acceptable salts, solvates, or polymorphs thereof, which are useful for inducing the formation of cochlear hair cells; and methods of treating hearing impairments or disorders using the compositions. In one aspect, the invention relates to pharmaceutical compositions comprising β-catenin; and agents that activate the expression of Atoh1, or pharmaceutically acceptable salts, solvates, or polymorphs thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Saturday, March 15, 2014 |
| APPL NO | 14/774597 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/44 (20130101) A61K 31/55 (20130101) Original (OR) Class A61K 31/222 (20130101) A61K 31/4418 (20130101) A61K 35/12 (20130101) A61K 38/17 (20130101) A61K 38/1703 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572820 | Deretic et al. |
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| APPLICANT(S) | Vojo Deretic (Placitas, New Mexico); Eliseo Castillo (Albuquerque, New Mexico); Steven Bradfute (Albuquerque, New Mexico); Larry A. Sklar (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Vojo Deretic (Placitas, New Mexico); Eliseo Castillo (Albuquerque, New Mexico); Steven Bradfute (Albuquerque, New Mexico); Larry A. Sklar (Albuquerque, New Mexico) |
| ABSTRACT | The invention provides methods of treating autophagy mediated diseases and disorders and related pharmaceutical compositions, diagnostics, screening techniques and kits. In one embodiment, the invention provides a method of determining whether a subject suffers from, or is at risk of developing, and autophagy mediated disease state and/or condition by evaluating LC3 levels. |
| FILED | Thursday, May 10, 2012 |
| APPL NO | 14/116581 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/54 (20130101) A61K 31/65 (20130101) Original (OR) Class A61K 31/436 (20130101) A61K 31/472 (20130101) A61K 31/473 (20130101) A61K 31/517 (20130101) A61K 31/519 (20130101) A61K 31/522 (20130101) A61K 31/546 (20130101) A61K 31/585 (20130101) A61K 31/4365 (20130101) A61K 31/4535 (20130101) A61K 31/5685 (20130101) Peptides C07K 16/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/56972 (20130101) G01N 2333/9015 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572830 | Wurtman |
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| APPLICANT(S) | Richard J. Wurtman (Boston, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Richard J. Wurtman (Boston, Massachusetts) |
| ABSTRACT | The present invention provides methods for increasing secretion of dopamine and other neurotransmitters and treating or reducing the incidence of diseases involving decreased secretion of dopamine and other neurotransmitters, e.g. Parkinson's disease, comprising administering to the subject a uridine or a source thereof, and compositions for treating or reducing an incidence of Parkinson's disease, comprising a uridine, a uridine monophosphate, or a source thereof. |
| FILED | Wednesday, May 11, 2005 |
| APPL NO | 11/126410 |
| ART UNIT | 1673 — Organic Chemistry |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/10 (20160801) A23L 33/13 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2002/00 (20130101) A23V 2200/322 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/513 (20130101) A61K 31/685 (20130101) A61K 31/7072 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572834 | Tour et al. |
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| APPLICANT(S) | James M. Tour (Bellaire, Texas); Jacob Berlin (Monrovia, California); Daniela Marcano (Houston, Texas); Ashley Leonard (Houston, Texas); Thomas A. Kent (Houston, Texas); Robia G. Pautler (Pearland, Texas); Brittany Bitner (Dallas Center, Iowa); Taeko Inoue (Pasadena, Texas) |
| ASSIGNEE(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas); BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | James M. Tour (Bellaire, Texas); Jacob Berlin (Monrovia, California); Daniela Marcano (Houston, Texas); Ashley Leonard (Houston, Texas); Thomas A. Kent (Houston, Texas); Robia G. Pautler (Pearland, Texas); Brittany Bitner (Dallas Center, Iowa); Taeko Inoue (Pasadena, Texas) |
| ABSTRACT | In some embodiments, the present invention provides methods of treating oxidative stress in a subject by administering a therapeutic composition to the subject. In some embodiments, the therapeutic composition comprises a carbon nanomaterial with anti-oxidant activity. In some embodiments, the anti-oxidant activity of the carbon nanomaterial corresponds to ORAC values between about 200 to about 15,000. In some embodiments, the administered carbon nanomaterials include at least one of single-walled nanotubes, double-walled nanotubes, triple-walled nanotubes, multi-walled nanotubes, ultra-short nanotubes, graphene, graphene nanoribbons, graphite, graphite oxide nanoribbons, carbon black, oxidized carbon black, hydrophilic carbon clusters, and combinations thereof. In some embodiments, the carbon nanomaterial is an ultra-short single-walled nanotube that is functionalized with a plurality of solubilizing groups. In some embodiments, the carbon nanomaterial is a polyethylene glycol functionalized hydrophilic carbon cluster (PEG-HCC). In some embodiments, the administered therapeutic compositions of the present invention may also include an active agent or targeting agent associated with the carbon nanomaterial. Additional embodiments of the present invention pertain to the aforementioned carbon nanomaterial compositions for treating oxidative stress. |
| FILED | Thursday, April 26, 2012 |
| APPL NO | 14/114007 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 33/44 (20130101) Original (OR) Class A61K 33/44 (20130101) A61K 45/06 (20130101) A61K 47/48215 (20130101) A61K 47/48869 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572836 | June et al. |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Carl H. June (Merion Station, Pennsylvania); Bruce L. Levine (Cherry Hill, New Jersey); Michael D. Kalos (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention relates to of analyzing vector supernatants useful for transducing T cells destined for administration to a human subject. The invention also related to methods of analyzing transduced T cells destined for administration to a human subject. |
| FILED | Friday, July 12, 2013 |
| APPL NO | 14/412844 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class Peptides C07K 16/2803 (20130101) C07K 2317/622 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) C12Q 1/701 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/92 (20130101) G01N 33/569 (20130101) G01N 33/56933 (20130101) G01N 33/56983 (20130101) G01N 2333/37 (20130101) G01N 2333/195 (20130101) G01N 2400/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572843 | Dang et al. |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Long Dang (Baltimore, Maryland); Chetan Bettegowda (Perry Hall, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland) |
| ABSTRACT | Current approaches for treating cancer are limited, in part, by the inability of drugs to affect the poorly vascularized regions of tumors. We have found that spores of anaerobic bacteria in combination with agents which interact with microtubules can cause the destruction of both the vascular and avascular compartments of tumors. Two classes of microtubule inhibitors were found to exert markedly different effects. Some agents that inhibited microtubule synthesis, such as vinorelbine, caused rapid, massive hemorrhagic necrosis when used in combination with spores. In contrast, agents that stabilized microtubules, such as the taxane, docetaxel, resulted in slow tumor regressions that killed most neoplastic cells. Remaining cells in the poorly perfused regions of tumors could be eradicated by sporulated bacteria. Mechanistic studies showed that the microtubule destabilizers, but not the microtubule stabilizers, radically reduced blood flow to tumors, thereby enlarging the hypoxic niche in which spores could germinate. A single intravenous injection of spores plus selected microtubule-interacting agents was able to cause regressions of several tumors in the absence of excessive toxicity. |
| FILED | Monday, December 16, 2013 |
| APPL NO | 14/106987 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) A61K 31/337 (20130101) A61K 31/427 (20130101) A61K 31/427 (20130101) A61K 35/742 (20130101) Original (OR) Class A61K 35/742 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 435/842 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572854 | Anderson et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Kenneth C. Anderson (Wellesley, Massachusetts); James E. Bradner (Weston, Massachusetts); Edward Franklin Greenberg (Cleveland, Ohio); Teru Hideshima (Brookline, Massachusetts); Nicholas Paul Kwiatkowski (Auburn, Massachusetts); Ralph Mazitschek (Belmont, Massachusetts); Stuart L. Schreiber (Boston, Massachusetts); Jared Shaw (Davis, California); Stephen J. Haggarty (Gloucester, Massachusetts) |
| ABSTRACT | The invention relates to methods of treating protein degradation disorders, such cellular proliferative disorders (e.g., cancer) and protein deposition disorders (e.g., neurodegenerative disorders). The invention provides methods and pharmaceutical compositions for treating these diseases using aggresome inhibitors or combinations of aggresome inhibitors and proteasome inhibitors. The invention further relates to methods and pharmaceutical compositions for treating multiple myeloma. New HDAC/TDAC inhibitors and aggresome inhibitors are also provided as well as synthetic methodologies for preparing these compounds. |
| FILED | Monday, April 06, 2015 |
| APPL NO | 14/679800 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/35 (20130101) A61K 31/35 (20130101) A61K 31/69 (20130101) A61K 31/69 (20130101) A61K 31/357 (20130101) A61K 31/357 (20130101) A61K 31/422 (20130101) A61K 31/4965 (20130101) A61K 31/4965 (20130101) A61K 38/05 (20130101) Original (OR) Class A61K 38/50 (20130101) A61K 38/50 (20130101) A61K 45/06 (20130101) A61K 49/0008 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572855 | Kufe et al. |
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| FUNDED BY |
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| APPLICANT(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); GENUS ONCOLOGY, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC. (Boston, Massachusetts); GENUS ONCOLOGY, LLC (Chicago, Illinois) |
| INVENTOR(S) | Donald W. Kufe (Wellesley, Massachusetts); Surender Kharbanda (Natick, Massachusetts) |
| ABSTRACT | The invention provides for treatment of MUC1+/ERα+/− cancers using an anti-MUC1 therapy, optionally including an anti-ERα therapy. In particular, the invention addresses the treatment of tamoxifen-resistant cancers, using MUC1+, and optionally anti-ERα therapy. |
| FILED | Monday, March 10, 2014 |
| APPL NO | 14/774163 |
| ART UNIT | 1675 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/138 (20130101) A61K 31/138 (20130101) A61K 38/07 (20130101) Original (OR) Class A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/1735 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572860 | Brinton et al. |
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| FUNDED BY |
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| APPLICANT(S) | Margo A. Brinton (Decatur, Georgia); Mohamed M. Emara (Atlanta, Georgia) |
| ASSIGNEE(S) | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Atlanta, Georgia) |
| INVENTOR(S) | Margo A. Brinton (Decatur, Georgia); Mohamed M. Emara (Atlanta, Georgia) |
| ABSTRACT | The present invention is directed to methods and compositions that are effective in the inhibition of viral replication. In particular, the methods and compositions are effective at interfering with the activity of host cell proteins required in viral replication. For example, an embodiment of the invention is directed to methods and compositions comprising RNA sequences to which the host cell proteins TIAR and/or TIA-1 bind. |
| FILED | Monday, July 16, 2007 |
| APPL NO | 11/879493 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/162 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/115 (20130101) C12N 15/1131 (20130101) C12N 2310/13 (20130101) C12N 2770/24111 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572861 | Sasisekharan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ram Sasisekharan (Lexington, Massachusetts); Karthik Viswanathan (Waltham, Massachusetts); Venkataramanan Soundararajan (Windham, New Hampshire); S. Raguram (Hillsborough, New Jersey); Viswanathan Sasisekharan (Cambridge, Massachusetts); Vidya Subramanian (Somerville, Massachusetts) |
| ABSTRACT | The present invention provides novel agents for broad spectrum influenza neutralization. The present invention provides agents for inhibiting influenza infection by bind to the influenza virus and/or hemagglutinin (HA) polypeptides and/or HA receptors, and reagents and methods relating thereto. The present invention provides a system for analyzing interactions between infolds and the interaction partners that bind to them. |
| FILED | Friday, April 08, 2016 |
| APPL NO | 15/094522 |
| ART UNIT | 1675 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 9/0073 (20130101) A61K 38/162 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/16122 (20130101) C12N 2760/16133 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572864 | Cummings et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Richard D. Cummings (Atlanta, Georgia); Sean R. Stowell (Decatur, Georgia); Connie Arthur (Decatur, Georgia) |
| ABSTRACT | The disclosure relates to uses of a purified or isolated lectin to kill bacteria, viruses, and other pathogens. In certain embodiments, the disclosure relates to method of treating or preventing an infection comprising administering a purified or isolated galectin to a subject in need thereof. In certain embodiments, the subject is at risk of, exhibiting symptoms of, or diagnosed with a pathogenic infection. |
| FILED | Friday, December 11, 2015 |
| APPL NO | 14/966941 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/178 (20130101) A61K 38/178 (20130101) A61K 38/1732 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572869 | Hocking et al. |
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| FUNDED BY |
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| APPLICANT(S) | Denise Hocking (Rochester, New York); Daniel C. Roy (San Antonio, Texas) |
| ASSIGNEE(S) | University of Rochester (Rochester, New York) |
| INVENTOR(S) | Denise Hocking (Rochester, New York); Daniel C. Roy (San Antonio, Texas) |
| ABSTRACT | The present invention is directed to recombinant fibronectin peptide mimetics and wound healing compositions the same. Other aspects of the present invention include wound healing dressings that comprise the healing composition of the present invention and a wound dressings material and methods of treating wounds using these compositions. |
| FILED | Thursday, June 18, 2015 |
| APPL NO | 14/743485 |
| ART UNIT | 1676 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/18 (20130101) A61K 38/39 (20130101) Original (OR) Class A61K 38/1709 (20130101) A61K 45/06 (20130101) A61K 47/42 (20130101) Peptides C07K 14/47 (20130101) C07K 14/78 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572875 | Livingston et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York) |
| ASSIGNEE(S) | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (New York, New York) |
| INVENTOR(S) | Philip O. Livingston (New York, New York); Govindaswami Ragupathi (New York, New York); Samuel J. Danishefsky (Englewood, New Jersey) |
| ABSTRACT | This invention provides a polyvalent vaccine comprising at least two conjugated antigens selected from a group containing glycolipid antigen, polysaccharide antigen, mucin antigen, glycosylated mucin antigen and an appropriate adjuvant. This invention also provides a multivalent vaccine comprising at least two of the following: glycosylated MUC-1-32mer, Globo H, GM2, Ley, Tn(c), sTN(c), and TF(c). This invention provides the vaccine above, wherein the adjuvant is saponin-based adjuvant. This invention provides a method for inducing immune response in a subject comprising administering an effective amount of the vaccine above to the subject. Finally, this invention provides a method for treating cancer in a subject comprising administering an appropriate amount of the vaccine above to the subject. |
| FILED | Thursday, October 01, 2015 |
| APPL NO | 14/872232 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/385 (20130101) A61K 47/4833 (20130101) A61K 2039/70 (20130101) A61K 2039/545 (20130101) A61K 2039/575 (20130101) A61K 2039/627 (20130101) A61K 2039/6081 (20130101) A61K 2039/55577 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572876 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jianrong Li (Dublin, Ohio); Yu Zhang (Columbus, Ohio); Rongzhang Wang (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Jianrong Li (Dublin, Ohio); Yu Zhang (Columbus, Ohio); Rongzhang Wang (Columbus, Ohio) |
| ABSTRACT | The present invention includes methyltransferase (MTase)-defective recombinant viruses as live vaccine candidates for human metapneumovirus (hMPV), human respiratory syncytial virus (hRSV), and human parainfluenza virus type 3 (PIV3). Here the inventors provide the technical description for generating MTase-defective paramyxoviruses useful as immunogens, as well as related materials and methods. |
| FILED | Monday, June 11, 2012 |
| APPL NO | 14/124501 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/45 (20130101) A61K 39/12 (20130101) A61K 39/155 (20130101) Original (OR) Class A61K 2039/542 (20130101) A61K 2039/543 (20130101) A61K 2039/5254 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/18334 (20130101) C12N 2760/18362 (20130101) C12N 2760/18534 (20130101) C12N 2760/18562 (20130101) C12N 2760/18634 (20130101) C12N 2760/18662 (20130101) Enzymes C12Y 207/07006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572879 | Lu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOSTON MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | Boston Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Weining Lu (West Roxbury, Massachusetts); Xueping Fan (Braintree, Massachusetts); David J. Salant (Newton, Massachusetts) |
| ABSTRACT | Provided herein are methods for the treatment of chronic kidney disease and proteinuria and for the diagnosis of chronic kidney disease and monitoring the effects of treatment on the progression of chronic kidney disease and proteinuria based on unexpected roles for the SLIT-ROBO signaling pathway in the regulation of podocyte F-actin cytoskeleton and foot process structure in the kidney. |
| FILED | Friday, January 04, 2013 |
| APPL NO | 14/369094 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 38/177 (20130101) A61K 38/177 (20130101) A61K 38/1709 (20130101) A61K 38/1774 (20130101) A61K 39/3955 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/47 (20130101) C07K 14/70503 (20130101) C07K 16/18 (20130101) C07K 2317/24 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/115 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2333/70503 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572894 | Salem et al. |
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| FUNDED BY |
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| APPLICANT(S) | Aliasger K. Salem (Iowa City, Iowa); Sean M. Geary (Iowa City, Iowa); George J. Weiner (Iowa City, Iowa); Caitlin Lemke (Iowa City, Iowa); Yogita Krishnamachari (Iowa City, Iowa) |
| ASSIGNEE(S) | The University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Aliasger K. Salem (Iowa City, Iowa); Sean M. Geary (Iowa City, Iowa); George J. Weiner (Iowa City, Iowa); Caitlin Lemke (Iowa City, Iowa); Yogita Krishnamachari (Iowa City, Iowa) |
| ABSTRACT | The present invention provides three-component compositions comprising microparticles, a tumor antigen, a first immune adjuvant, and a second immune adjuvant. Also provided are chemo-immunotherapeutic compositions comprising microparticles, a chemotherapeutic agent, and an immune adjuvant. |
| FILED | Tuesday, October 18, 2011 |
| APPL NO | 13/878561 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1647 (20130101) A61K 31/704 (20130101) A61K 39/0011 (20130101) A61K 39/0011 (20130101) A61K 39/39 (20130101) A61K 47/48092 (20130101) A61K 47/48876 (20130101) Original (OR) Class A61K 2039/55511 (20130101) A61K 2039/55555 (20130101) A61K 2039/55561 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572895 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jianjun Cheng (Champaign, Illinois); Nathan Gabrielson (Rockford, Illinois); Yin Lichen (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Jianjun Cheng (Champaign, Illinois); Nathan Gabrielson (Rockford, Illinois); Yin Lichen (Urbana, Illinois) |
| ABSTRACT | The invention provides a composition comprising two or more of a) genetic material; b) a condensing agent; c) a membrane destabilizing agent; d) a targeting/stabilizing agent, and optionally e) an ionic cross-linking agent. The components of the composition can self-assemble to form particles via electrostatic and/or lipophilic interactions. Methods of making and using the composition are also provided. The compositions can be used, for example, to transfer genetic material to cells in vitro or in vivo. |
| FILED | Friday, August 05, 2011 |
| APPL NO | 13/814688 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 9/5123 (20130101) A61K 31/7088 (20130101) A61K 47/18 (20130101) A61K 47/183 (20130101) A61K 48/00 (20130101) A61K 48/0025 (20130101) Original (OR) Class A61K 48/0033 (20130101) A61K 48/0041 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572910 | Messersmith et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Phillip B. Messersmith (Clarendon Hills, Illinois); Lihong He (Wilmette, Illinois); Dominic E. Fullenkamp (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Phillip B. Messersmith (Clarendon Hills, Illinois); Lihong He (Wilmette, Illinois); Dominic E. Fullenkamp (Evanston, Illinois) |
| ABSTRACT | Biocompatible hydrogels made from cross-linked catechol-borate ester polymers are disclosed, along with methods of synthesizing and using such hydrogels. The hydrogels of the present invention are prepared by boronic acid-catechol complexation between catechol-containing macromonomers and boronic acid-containing cross-linkers. The resulting hydrogels are pH-responsive and self-healing, and can be used in a number of different biomedical applications, including in surgical implants, in surgical adhesives, and in drug delivery systems is data provides further evidence of the viability of using the disclosed hydrogels for in vivo in biomedical applications. |
| FILED | Monday, May 21, 2012 |
| APPL NO | 13/476422 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/26 (20130101) A61L 15/26 (20130101) A61L 27/18 (20130101) Original (OR) Class A61L 27/18 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 120/56 (20130101) C08F 220/34 (20130101) C08F 220/34 (20130101) C08F 2220/286 (20130101) C08F 2220/603 (20130101) C08F 2220/603 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/328 (20130101) C08G 65/337 (20130101) C08G 2650/50 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) C08L 71/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572979 | Fridman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Gene Yevgeny Fridman (Baltimore, Maryland); Charles Coleman Della Santina (Towson, Maryland) |
| ABSTRACT | An embodiment in accordance with the present invention provides a device and method to deliver direct ionic current safely to target neural tissue, while also eliminating interruptions in the output of the device that can result from the non-ideal operation of the valves used to control the current flow in the device. The device includes two valve-operated systems that work in tandem. The first and second current producing systems are configured to be used together in order to eliminate the periodic interruptions in current flow. In use, one system drives current through the target tissue, while the other system closes all of the valves first and then opens its valves in sequence. This intermediate step of closing all of the valves prevents unintended current shunts through either system. The device also includes two conductors to direct the flow of direct current into the target tissue. |
| FILED | Thursday, December 20, 2012 |
| APPL NO | 14/366870 |
| ART UNIT | 3766 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/20 (20130101) A61N 1/32 (20130101) A61N 1/44 (20130101) A61N 1/303 (20130101) A61N 1/325 (20130101) Original (OR) Class A61N 1/3605 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09572981 — Methods and systems for customizing cochlear implant stimulation and applications of same
| US 09572981 | Noble et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Jack H. Noble (Nashville, Tennessee); Rene H. Gifford (Franklin, Tennessee); Robert F. Labadie (Nashville, Tennessee); Benoit M. Dawant (Nashville, Tennessee) |
| ABSTRACT | One aspect of the invention provides a method for customizing cochlear implant stimulation of a living subject. The cochlear implant includes an electrode array having a plurality of electrodes implanted in a cochlea of the living subject. The method includes determining a position for each of the plurality of electrodes and spiral ganglion nerves that the electrode array stimulates, determining a geometric relationship between neural pathways within the cochlea and the electrode array implanted therein, and using one or more electrodes of the electrode array to stimulate a group of SG neural pathways of the cochlea based on the location of the one or more electrodes and their geometric relationship with the neural pathways. |
| FILED | Wednesday, April 03, 2013 |
| APPL NO | 14/390503 |
| ART UNIT | 3766 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/12 (20130101) A61B 5/4893 (20130101) A61B 6/032 (20130101) A61B 6/501 (20130101) A61B 6/5235 (20130101) A61B 2034/104 (20160201) A61B 2034/105 (20160201) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0541 (20130101) A61N 1/36032 (20130101) Original (OR) Class A61N 1/36185 (20130101) Electric Digital Data Processing G06F 19/3437 (20130101) Image Data Processing or Generation, in General G06T 7/0024 (20130101) G06T 7/0083 (20130101) G06T 7/0089 (20130101) G06T 2207/10081 (20130101) G06T 2207/20124 (20130101) G06T 2207/20128 (20130101) G06T 2207/30052 (20130101) Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 25/50 (20130101) H04R 25/606 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573147 | Yeates et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KAER BIOTHERAPEUTICS CORPORATION (Escondido, California) |
| ASSIGNEE(S) | KAER Biotherapeutics Corporation (Escondido, California) |
| INVENTOR(S) | Donovan B Yeates (Escondido, California); Xin Heng (McKinney, Texas) |
| ABSTRACT | A nozzle and a method of generating an aerosol from a fluid and a gas by operating the nozzle. The nozzle has an aerosol exit orifice of a larger diameter and a fluid exit orifice of a smaller diameter aligned on a common central axis. A pressurized gas from a pressurized gas exit in close proximity to the fluid exit orifice intersects a fluid jet exiting from the fluid exit orifice at that acute angle and in a distance from the aerosol exit orifice. The method includes aerosolizing a fluid with a viscosity exceeding 4 cSt delivering an inhalable medication at a rate of more than 1 ml/minute, thereby delivering a medication at a mass flow rate of at least 30 mg/minute in form of the fluid particles having a mass median aerodynamic diameter (MMAD) of 6 μm or less. |
| FILED | Friday, April 15, 2016 |
| APPL NO | 15/130235 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/001 (20140204) A61M 11/06 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 1/02 (20130101) B05B 7/10 (20130101) B05B 7/12 (20130101) B05B 7/0475 (20130101) B05B 7/0483 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573148 | Yeates |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Donovan Yeates (Escondido, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donovan Yeates (Escondido, California) |
| ABSTRACT | A method of aerosolizing a liquid by generating an aerosol from a liquid fluid and a gas with a nozzle having a cone-shaped gas exit channel, the method including the method steps of: ejecting a nozzle gas jet through an orifice at the cone apex; generating a zone of low pressure by the ejected nozzle gas jet, the zone of low pressure augmenting a flow of liquid fluid in a direction from a nozzle cone base towards the orifice at the cone apex; and aerosolizing the liquid fluid at the aerosolizing perimeter where the liquid fluid that flows towards the orifice is sheared by the nozzle gas jet. |
| FILED | Wednesday, July 23, 2014 |
| APPL NO | 14/339399 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/06 (20130101) A61M 15/008 (20140204) A61M 15/0086 (20130101) A61M 2016/0036 (20130101) A61M 2205/362 (20130101) A61M 2205/368 (20130101) Separation B01D 45/08 (20130101) Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573880 | Petasis |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Nicos A. Petasis (Hacienda Heights, California) |
| ABSTRACT | Benzolipoxin analogs, methods of their preparation and pharmaceutical compositions containing the compounds are provided. The compounds and compositions are useful in methods for treatment of various diseases, including, inflammation, autoimmune disease and abnormal cell proliferation. |
| FILED | Friday, August 01, 2014 |
| APPL NO | 14/450017 |
| ART UNIT | 1672 — Organic Chemistry |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/14 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/216 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 69/618 (20130101) Original (OR) Class C07C 69/732 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573885 | Pelletier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aeromics, Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | AEROMICS, INC. (Cleveland, Ohio) |
| INVENTOR(S) | Marc F. Pelletier (Shaker Heights, Ohio); George William Farr (Rocky River, Ohio); Paul Robert McGuirk (Spring Hill, Florida); Christopher H. Hall (Shaker Heights, Ohio); Walter F. Boron (Shaker Heights, Ohio) |
| ABSTRACT | The present invention relates to the use of selective aquaporin inhibitors, e.g., of aquaporin-4 or aquaporin-2, e.g., certain phenylbenzamide compounds, for the prophylaxis, treatment and control of aquaporin-mediated conditions, e.g., diseases of water imbalance, for example edema (particularly edema of the brain and spinal cord, e.g., following trauma or ischemic stroke, as well as the edema associated with glioma, meningitis, acute mountain sickness, epileptic seizures, infections, metabolic disorders, hypoxia, water intoxication, hepatic failure, hepatic encephalopathy, diabetic ketoacidosis, abscess, eclampsia, Creutzfeldt-Jakob disease, and lupus cerebritis, as well as edema consequent to microgravity and/or radiation exposure, as well as edema consequent to invasive central nervous system procedures, e.g., neurosurgery, endovascular clot removal, spinal tap, aneurysm repair, or deep brain stimulation, as well as retinal edema), as well as hyponatremia and excess fluid retention, and diseases such as epilepsy, retinal ischemia and other diseases of the eye associated with abnormalities in intraocular pressure and/or tissue hydration, myocardial ischemia, myocardial ischemia/reperfusion injury, myocardial infarction, myocardial hypoxia, congestive heart failure, sepsis, and neuromyelitis optica, as well as migraines, as well as to novel assays for identifying aquaporin inhibitors. |
| FILED | Saturday, June 27, 2015 |
| APPL NO | 14/752839 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/24 (20130101) A61K 31/167 (20130101) A61K 31/661 (20130101) A61K 31/5375 (20130101) A61K 31/6615 (20130101) Acyclic or Carbocyclic Compounds C07C 235/64 (20130101) Original (OR) Class Heterocyclic Compounds C07D 295/185 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573906 | Wagner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carl E. Wagner (Glendale, Arizona); Peter W. Jurutka (Scottsdale, Arizona); Pamela A. Marshall (Peoria, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, A Body Corporate of the State of Arizona Acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Carl E. Wagner (Glendale, Arizona); Peter W. Jurutka (Scottsdale, Arizona); Pamela A. Marshall (Peoria, Arizona) |
| ABSTRACT | The invention provides compounds of formulae (I), (II), (III), and (IV): and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers and Alzheimer's disease. |
| FILED | Thursday, September 13, 2012 |
| APPL NO | 14/344867 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 57/50 (20130101) C07C 57/62 (20130101) C07C 59/54 (20130101) C07C 2102/10 (20130101) Heterocyclic Compounds C07D 213/55 (20130101) C07D 213/80 (20130101) C07D 239/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573908 | Bassler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bonnie L. Bassler (Princeton, New Jersey); Wai-Leung Ng (Lawrenceville, New Jersey); Lark J. Perez (Ewing, New Jersey); Jianping Cong (Plainsboro, New Jersey); Martin F. Semmelhack (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Bonnie L. Bassler (Princeton, New Jersey); Wai-Leung Ng (Lawrenceville, New Jersey); Lark J. Perez (Ewing, New Jersey); Jianping Cong (Plainsboro, New Jersey); Martin F. Semmelhack (Princeton, New Jersey) |
| ABSTRACT | Using a whole-cell high-throughput screen, eleven molecules were identified that activate V. cholerae quorum sensing (QS). Eight molecules are receptor agonists and three molecules are antagonists of LuxO, the central NtrC-type response regulator that controls the global V. cholerae QS cascade. Pro-QS molecules are used for the development of novel anti-infectives. |
| FILED | Wednesday, February 20, 2013 |
| APPL NO | 14/381432 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/707 (20130101) A01N 55/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) Heterocyclic Compounds C07D 253/075 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573911 | Kahne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Suzanne Walker Kahne (Brookline, Massachusetts); Jiaoyang Jiang (Boston, Massachusetts); Michael Block Lazarus (West Newton, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Suzanne Walker Kahne (Brookline, Massachusetts); Jiaoyang Jiang (Boston, Massachusetts); Michael Block Lazarus (West Newton, Massachusetts) |
| ABSTRACT | The present invention provides compounds of Formulae (I)-(V), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. In one aspect, compounds of the present invention are useful as glycosyltransferase inhibitors, in particular, O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) inhibitors. In another aspect, compounds of the present invention are useful as kinase inhibitors, in particular, PLK1 inhibitors, GSK3P inhibitors, or MAPKAPK2 inhibitors. The present invention further provides methods of using the inventive compounds, e.g., as biological probes to study the inhibition of OGT and/or kinase activity and as therapeutics, e.g., for the treatment of OGT-associated and/or kinase-associated conditions. |
| FILED | Friday, July 06, 2012 |
| APPL NO | 14/131024 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 263/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573977 | Burke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Jason Burke (Santa Cruz, California); Seth Rubin (Santa Cruz, California) |
| ABSTRACT | A method for preventing neoplastic transformation by inhibition of cell cycle progression into S phase by preventing the inactivation of Retinoblastoma protein (Rb). |
| FILED | Thursday, May 05, 2016 |
| APPL NO | 15/147609 |
| ART UNIT | 1675 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/08 (20130101) Peptides C07K 7/06 (20130101) C07K 7/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573983 | Siahaan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kansas (Lawrence, Kansas) |
| ASSIGNEE(S) | UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| INVENTOR(S) | Teruna J. Siahaan (Lawrence, Kansas); Prakash Manikwar (Lawrence, Kansas); Paul Kipkemboi Kiptoo (Lawrence, Kansas); Ahmed Badawi (Overland Park, Kansas); Barlas Buyuktimkin (Lawrence, Kansas); John M. Stewart (Lawrence, Kansas) |
| ABSTRACT | The present disclosure provides IDAC compounds capable of presenting two or more signal 1 moieties to a host immune system and methods of using the IDAC compounds to treat or prevent autoimmune disorders in a subject. The present disclosure provides compounds including a modified I-domain peptide having two or more modified lysine residues and two or more signal 1 moieities conjugated to the modified lysine residues of the I-domain peptide and methods of using an making the compounds. |
| FILED | Friday, January 04, 2013 |
| APPL NO | 13/733991 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 14/4713 (20130101) Original (OR) Class C07K 14/70553 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574001 | Wisniewski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas M. Wisniewski (Staten Island, New York); Wei Zhang (Shanghai, China PRC); Suying Dang (Shanghai, China PRC) |
| ASSIGNEE(S) | New York University (New York, New York) |
| INVENTOR(S) | Thomas M. Wisniewski (Staten Island, New York); Wei Zhang (Shanghai, China PRC); Suying Dang (Shanghai, China PRC) |
| ABSTRACT | The present invention relates to methods inhibiting tumor metastasis and treating cancer in a subject that involve administering to the subject an antibody which recognizes GPIIIa49-66, under conditions effective to inhibit tumor metastasis and/or treat cancer in the subject. |
| FILED | Friday, August 02, 2013 |
| APPL NO | 13/958145 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/2848 (20130101) Original (OR) Class C07K 2317/73 (20130101) C07K 2317/622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574013 | Gruber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee); ARONORA, INC. (Portland, Oregon); OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee); ARONORA, INC. (Portland, Oregon); OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| INVENTOR(S) | Andras Gruber (Portland, Oregon); David Gailani (Nashville, Tennessee); Philberta Leung (Portland, Oregon); Anton Matafonov (Nashville, Tennessee) |
| ABSTRACT | Provided are antibodies that selectively bind to and inhibit activation of coagulation factor XII. Methods of treatment employing these antibodies are described herein. |
| FILED | Friday, December 06, 2013 |
| APPL NO | 14/649972 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) A61K 2039/507 (20130101) Peptides C07K 16/36 (20130101) C07K 16/40 (20130101) Original (OR) Class C07K 2317/33 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574015 | Burden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steven J. Burden (Sharon, Connecticut); Wei Zhang (New York, New York); Maartje Huijbers (Leiden, Netherlands); Johannes J. Verschuuren (Oegstgeest, Netherlands); Silvère M. van der Maarel (Oegstgeest, Netherlands) |
| ASSIGNEE(S) | New York University (New York, New York); Leiden University Medical Center (Leiden, Netherlands) |
| INVENTOR(S) | Steven J. Burden (Sharon, Connecticut); Wei Zhang (New York, New York); Maartje Huijbers (Leiden, Netherlands); Johannes J. Verschuuren (Oegstgeest, Netherlands); Silvère M. van der Maarel (Oegstgeest, Netherlands) |
| ABSTRACT | Agents, compositions, and medicaments that reduce interactions between muscle specific kinase receptor (MuSK) and pathogenic immunoglobulin G4 (IgG4) antibodies specific for the first Ig-like domain of MuSK and methods and uses thereof to reduce such interactions are encompassed herein. Also encompassed are screening assays to identify inhibitors of these pathogenic antibodies, particularly those that reduce binding to MuSK. Agents identified using the screening assays described herein are envisioned for use as therapeutics, alone or in compositions or in medicaments, to improve motor function in subjects afflicted MuSK-MG. |
| FILED | Monday, September 15, 2014 |
| APPL NO | 14/486400 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/16 (20130101) A61K 38/1774 (20130101) Peptides C07K 14/705 (20130101) C07K 14/4713 (20130101) C07K 14/70503 (20130101) C07K 16/4258 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574184 | Grabowski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | Gregory A. Grabowski (Lexington, Massachusetts); Benjamin Liou (Cincinnati, Ohio) |
| ABSTRACT | The present disclosure relates to methods of treating diseases states such as lysosomal storage diseases and/or neurodegenerative diseases. Also disclosed are one or more compositions that may be useful for one or more of the disclosed methods, including compositions that may comprise acid β-glucosidase (GCase) protein comprising one or more mutations, peptides of acid β-glucosidase, and DNA vectors and cell lines related to acid β-glucosidase peptides or proteins. |
| FILED | Tuesday, September 23, 2014 |
| APPL NO | 14/494065 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2402 (20130101) Original (OR) Class Enzymes C12Y 302/01045 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574191 | Corey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David R. Corey (Dallas, Texas); Jiaxin Hu (Dallas, Texas); Dinah W. Y. Sah (Hopkinton, Massachusetts) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | David R. Corey (Dallas, Texas); Jiaxin Hu (Dallas, Texas); Dinah W. Y. Sah (Hopkinton, Massachusetts) |
| ABSTRACT | The present invention relates to the selective inhibition of protein expression of CAG repeat-related disease proteins such as Huntingtin Disease Protein and Ataxin-3 using double-stranded RNAs and nucleic acid analogs. Chemically-modified RNAs having at least one mismatch as compared to the target CAG repeat sequence are specifically contemplated. |
| FILED | Thursday, February 03, 2011 |
| APPL NO | 13/575842 |
| ART UNIT | 1674 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 38/1709 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/315 (20130101) C12N 2310/321 (20130101) C12N 2310/321 (20130101) C12N 2310/332 (20130101) C12N 2310/346 (20130101) C12N 2310/533 (20130101) C12N 2310/3521 (20130101) C12N 2320/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574220 | Eckhardt et al. |
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| FUNDED BY |
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| APPLICANT(S) | Advanced Liquid Logic, Inc. (San Diego, California) |
| ASSIGNEE(S) | Advanced Liquid Logic, Inc. (San Diego, California) |
| INVENTOR(S) | Allen E Eckhardt (San Diego, California); Carrie Graham (Raleigh, North Carolina); Ramakrishna Sista (San Diego, California); Vamsee K. Pamula (Cary, North Carolina); Theodore Winger (Morrisville, North Carolina); Tong Wang (Cary, North Carolina); Yalin Xiong (Morrisville, North Carolina); Ning Wu (Raleigh, North Carolina); Sanjay Saha (Andhra Pradesh, India); Gajendrasinh Raolji (Andhra Pradesh, India); Raveendra Dayam (Andhra Pradesh, India) |
| ABSTRACT | The invention is directed to droplet actuator devices and assay methods. The invention includes assay methods of conducting an assay comprising combining a sample with an umbelliferyl derivative, wherein the sample potentially comprises an enzyme capable of cleaving the umbelliferyl derivative and where the umbelliferyl derivative comprises an umbelliferyl core modified with one or more modifying moieties. |
| FILED | Wednesday, March 11, 2015 |
| APPL NO | 14/644989 |
| ART UNIT | 1672 — Plants |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502784 (20130101) B01L 2300/18 (20130101) B01L 2300/0654 (20130101) B01L 2300/0816 (20130101) B01L 2400/043 (20130101) B01L 2400/0427 (20130101) Heterocyclic Compounds C07D 311/16 (20130101) C07D 311/18 (20130101) C07D 311/20 (20130101) C07D 405/12 (20130101) C07D 413/12 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/203 (20130101) C07H 17/075 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/25 (20130101) C12Q 1/34 (20130101) Original (OR) Class C12Q 1/44 (20130101) C12Q 1/54 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6452 (20130101) G01N 33/5438 (20130101) G01N 2333/916 (20130101) G01N 2333/926 (20130101) G01N 2800/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574228 | Gu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| ASSIGNEE(S) | The Curators of the University of Missouri (Columbia, Missouri) |
| INVENTOR(S) | Li-Qun Gu (Columbia, Missouri); Yong Wang (Columbia, Missouri); Kai Tian (Columbia, Missouri) |
| ABSTRACT | The present invention provides a new and improved oligonucleotide detection method based on the nanopore technology with a probe containing a complementary sequence to the target oligonucleotide and a terminal extension at the probe's 3′ terminus, 5′ terminus, or both termini. The improved nanopore sensor with the probe enables sensitive, selective, and direct detection, differentiation and quantification of target oligonucleotides such as miRNAs. The inventive detection method may also be employed as a non-invasive and cost-effective diagnostic method for cancer detection based on miRNA levels in the patient's blood sample. |
| FILED | Wednesday, June 15, 2016 |
| APPL NO | 15/183152 |
| ART UNIT | 1759 — Plants |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574231 | Gilbert et al. |
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| FUNDED BY |
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| APPLICANT(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION (Tallahassee, Florida) |
| ASSIGNEE(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida) |
| INVENTOR(S) | David M. Gilbert (Tallahassee, Florida); Tyrone Ryba (Sarasota, Florida); Ichiro Hiratani (Kobe, Japan) |
| ABSTRACT | Methods for identifying and/or distinguishing a homogeneous population of cells based on their replication domain timing profile using high resolution genomic arrays or sequencing procedures are provided. These methods may be used to compare the replication timing profile for a population of cells to another replication timing profile(s), a replication timing fingerprint, and/or one or more informative segments of a replication timing fingerprint, which may be simultaneously or previously determined and/or contained in a database, to determine whether there is a match between them. Based on such information, the identity of the population of cells may be determined, or the identity of the population of cells may be distinguished from other populations of cells or cell types. Methods for determining a replication timing fingerprint for particular cell types are also provided. |
| FILED | Friday, May 02, 2014 |
| APPL NO | 14/267953 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6804 (20130101) C12Q 1/6804 (20130101) C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6837 (20130101) Original (OR) Class C12Q 2525/101 (20130101) C12Q 2525/101 (20130101) C12Q 2525/101 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) C12Q 2565/501 (20130101) C12Q 2565/626 (20130101) C12Q 2565/626 (20130101) C12Q 2565/626 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574238 | Shaughnessy, Jr. et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| ASSIGNEE(S) | Board of Trustees of the University of Arkansas (Little Rock, Arkansas) |
| INVENTOR(S) | John D. Shaughnessy, Jr. (Roland, Arkansas); Bart Barlogie (Little Rock, Arkansas); Fenghuang Zhan (Salt Lake City, Utah) |
| ABSTRACT | Gene expression profiling is a powerful tool that has varied utility. It enables classification of multiple myeloma into subtypes and identifying genes directly involved in disease pathogensis and clinical manifestation. The present invention used gene expression profiling in large uniformly treated population of patients with myeloma to identify genes associated with poor prognosis. It also demonstrated that over-expression of CKS1B gene, mainly due to gene amplification that was determined by Fluorescent in-situ hybridization to impart a poor prognosis in multiple myeloma. It is further contemplated that therapeutic strategies that directly target CKS1B or related pathways may represent novel, and more specific means of treating high risk myeloma and may prevent its secondary evolution. |
| FILED | Wednesday, May 22, 2013 |
| APPL NO | 13/900393 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Electric Digital Data Processing G06F 19/18 (20130101) G06F 19/20 (20130101) G06F 19/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574241 | Ferrando et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Adolfo Ferrando (New York, New York); Raul Rabadan (New York, New York); Teresa Palomero (New York, New York) |
| ABSTRACT | Whole exome sequencing of 12 tumor-normal DNA pairs, RNAseq analysis and targeted deep sequencing identified new genetic alterations in PTCL transformation. These analyses identified highly recurrent epigenetic factor mutations in TET2, DN-MT3A and IDH2 as well as a new highly prevalent RHOA p.Gly17Val (NM_001664) mutation present in 22/35 (67%) of angioimmunoblastic T-cell lymphomas (AITL) and in 8/44 (18%) not otherwise specified PTCL (PTCL NOS) samples. Mechanistically, the RHOA Gly17Val protein interferes with RHOA signaling in biochemical and cellular assays, an effect potentially mediated by the sequestration of activated Guanine Exchange Factor (GEF) proteins. In addition, new and recurrent, genetic defects are described including mutations in FYN, ATM, B2M and CD58 implicating SRC signaling, impaired DNA damage response and escape from immune surveillance mechanisms in the pathogenesis of PTCL. |
| FILED | Tuesday, June 03, 2014 |
| APPL NO | 14/895287 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/506 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575061 | Haselton et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Frederick R. Haselton (Nashville, Tennessee); Joshua Robert Trantum (Nashville, Tennessee); David W. Wright (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | Frederick R. Haselton (Nashville, Tennessee); Joshua Robert Trantum (Nashville, Tennessee); David W. Wright (Nashville, Tennessee) |
| ABSTRACT | The present invention provides simple and inexpensive assays for the detection of virtually any analyte in any sample that is in liquid form or that can be solubilized. The assays utilize the fluid dynamics of drop evaporation whereby soluble materials, including analytes and particles binding thereto, are drawn to the edge of the drop and ultimately form a concentrated residual ring. The presence or absence of certain reagents can then be detected through a number of different approaches. |
| FILED | Wednesday, October 20, 2010 |
| APPL NO | 13/502966 |
| ART UNIT | 1677 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54313 (20130101) Original (OR) Class G01N 33/54393 (20130101) G01N 33/56905 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575065 | Hazen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CLEVELAND CLINIC FOUNDATION (Cleveland, Ohio) |
| ASSIGNEE(S) | The Cleveland Clinic Foundation (Cleveland, Ohio) |
| INVENTOR(S) | Stanley L. Hazen (Pepper Pike, Ohio); Renliang Zhang (Cleveland, Ohio) |
| ABSTRACT | Diagnostic tests for characterizing an individual's risk of developing or having a cardiovascular disease. In one embodiment the present diagnostic test comprises determining the level of myeloperoxidase (MPO) activity in a bodily sample obtained from the individual or test subject. In another embodiment, the diagnostic test comprises determining the level of MPO mass in a bodily sample obtained from the test subject. In another embodiment, the diagnostic test comprises determining the level of one or more select MPO-generated oxidation products in a bodily sample obtained from the test subject. The select MPO-generated oxidation products are dityrosine, nitrotyrosine, methionine sulphoxide or an MPO-generated lipid peroxidation products. Levels of MPO activity, MPO mass, or the select MPO-generated oxidation product in bodily samples from the test subject are then compared to a predetermined value that is derived from measurements of MPO activity, MPO mass, or the select MPO-generated oxidation product in comparable bodily samples obtained from the general population or a select population of human subjects. Such comparison characterizes the test subject's risk of developing CVD. |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/135730 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/616 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/28 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/28 (20130101) Enzymes C12Y 111/01007 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/573 (20130101) Original (OR) Class G01N 2333/908 (20130101) G01N 2800/32 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) G01N 2800/324 (20130101) Electric Digital Data Processing G06F 19/3431 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575070 | Tainsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Michael A. Tainsky (West Bloomfield, Michigan); Sorin Draghici (Troy, Michigan); Ho-Sheng Lin (Plymouth, Michigan) |
| ASSIGNEE(S) | Wayne State University (Detroit, Michigan) |
| INVENTOR(S) | Michael A. Tainsky (West Bloomfield, Michigan); Sorin Draghici (Troy, Michigan); Ho-Sheng Lin (Plymouth, Michigan) |
| ABSTRACT | A diagnostic device for and method of detecting the presence of head and neck squamous cell carcinoma (HNSCC) in a patient including a detector device for detecting a presence of at least one marker indicative of HNSCC, the detector device including a panel of markers for HNSCC. A diagnostic device for and method of staging HNSCC in a patient including a detector device for detecting a presence of at least one marker indicative of stages of HNSCC, the detector device including a panel of markers for HNSCC. Markers for head and neck squamous cell carcinoma selected from the markers listed in Table 5. Methods of personalized immunotherapy, making a personalized anti-cancer vaccine, and predicting a clinical outcome in a HNSCC patient. A method of making a panel of HNSCC markers. |
| FILED | Friday, September 21, 2007 |
| APPL NO | 11/903312 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 2319/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) Original (OR) Class G01N 33/6893 (20130101) G01N 2800/32 (20130101) G01N 2800/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575072 | Thadhani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ravi Thadhani (Boston, Massachusetts); Thomas P. Stossel (Belmont, Massachusetts); Po-Shun Lee (Brookline, Massachusetts); Ananth Karumanchi (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Ravi Thadhani (Boston, Massachusetts); Thomas P. Stossel (Belmont, Massachusetts); Po-Shun Lee (Brookline, Massachusetts); Ananth Karumanchi (Chestnut Hill, Massachusetts) |
| ABSTRACT | The invention is directed, in part, to the use of gelsolin to diagnose, monitor, and treat subjects with renal failure (e.g., chronic renal failure subjects on dialysis). |
| FILED | Friday, January 23, 2009 |
| APPL NO | 12/358868 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6883 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575073 | Das et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Medicine and Dentistry of New Jersey (Somerset, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey); MASSACHUSETTS GENERAL HOSPITAL (Boston, Massachusetts) |
| INVENTOR(S) | Kiron M. Das (Basking Ridge, New Jersey); Koushik K. Das (Boston, Massachusetts); Mari Mino-Kenudson (Burlington, Massachusetts) |
| ABSTRACT | The present invention relates to diagnostic, prognostic and clinical methods of distinguishing high-risk IPMN from more benign IPMN as well as high-grade PanIN and PDAC from low-grade PanIN with moderate sensitivity and very high specificity using Das-1 and related antibodies. |
| FILED | Wednesday, October 10, 2012 |
| APPL NO | 13/648921 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) Original (OR) Class G01N 33/57438 (20130101) G01N 2800/50 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575078 | Delmenico et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Coramed Technologies, LLC (Niles, Illinois) |
| ASSIGNEE(S) | Coramed Technologies, LLC (Glenview, Illinois) |
| INVENTOR(S) | Peter Delmenico (Chicago, Illinois); Carlos G. Lopez-Espina (Evanston, Illinois); Gabriel Raviv (Glenview, Illinois) |
| ABSTRACT | A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/212891 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502753 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/036 (20130101) G01N 33/86 (20130101) Original (OR) Class G01N 33/4905 (20130101) G01N 2291/0427 (20130101) G01N 2291/02818 (20130101) G01N 2291/02827 (20130101) G01N 2800/224 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575302 | Booth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ISIS Innovation Limited (Oxfordshire, United Kingdom) |
| ASSIGNEE(S) | ISIS Innovation Ltd (Oxfordshire, United Kingdom) |
| INVENTOR(S) | Martin Booth (Oxfordshire, United Kingdom); Daniel Burke (Oxfordshire, United Kingdom); Joerg Bewersdorf (New Haven, Connecticut); Travis J. Gould (New Haven, Connecticut) |
| ABSTRACT | Aberrations in stimulated emission depletion microscopy are corrected using an adaptive optics approach using a metric which combines both image sharpness and brightness. Light modulators (22,32) are used to perform aberration correction in one or more of the depletion path (10), the excitation path (12), or the emission path from sample to detector. |
| FILED | Friday, August 16, 2013 |
| APPL NO | 14/423188 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/636 (20130101) G01N 21/6456 (20130101) G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0072 (20130101) Original (OR) Class G02B 21/0076 (20130101) G02B 26/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09576570 | Precoda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kristin Precoda (Mountain View, California); Horacio Franco (Menlo Park, California); Jing Zheng (Sunnyvale, California); Michael Frandsen (Helena, Montana); Victor Abrash (Montara, California); Murat Akbacak (Palo Alto, California); Andreas Stolcke (Berkeley, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | Kristin Precoda (Mountain View, California); Horacio Franco (Menlo Park, California); Jing Zheng (Sunnyvale, California); Michael Frandsen (Helena, Montana); Victor Abrash (Montara, California); Murat Akbacak (Palo Alto, California); Andreas Stolcke (Berkeley, California) |
| ABSTRACT | The present invention relates to a method and apparatus for adding new vocabulary to interactive translation and dialog systems. In one embodiment, a method for adding a new word to a vocabulary of an interactive dialog includes receiving an input signal that includes at least one word not currently in the vocabulary, inserting the word into a dynamic component of a search graph associated with the vocabulary, and compiling the dynamic component independently of a permanent component of the search graph to produce a new sub-grammar, where the permanent component comprises a plurality of words that are permanently part of the search graph. |
| FILED | Friday, July 30, 2010 |
| APPL NO | 12/847826 |
| ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/06 (20130101) Original (OR) Class G10L 15/063 (20130101) G10L 15/193 (20130101) G10L 2015/0635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09578306 | Micheva et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Kristina D. Micheva (San Jose, California); Stephen J. Smith (Los Altos, California) |
| ABSTRACT | High-resolution three-dimensional imaging of a specimen is facilitated. According to an example embodiment of the present invention, a series of very thin slices from a specimen are serially and robustly arranged on an imaging device such as a microscope slide. The slices are imaged and the images are used to reconstruct a three-dimensional image having high resolution at depths into the specimen. The serial arrangement of the slices facilitates the proper ordering of images for reconstruction. Further, the robust nature of the slice arrangement facilitates treatment of the slices and, in some applications, multiple treatments with corresponding imaging sequences for each treatment. Various embodiments are directed to methods and arrangements for three-dimensional characterization of biological specimen and to data that is accessible and/or executable by a computer for linking different images together in order to characterize such biological specimen in three dimensions. |
| FILED | Monday, April 13, 2015 |
| APPL NO | 14/685111 |
| ART UNIT | 2667 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) G02B 21/367 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00134 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/0051 (20130101) Pictorial Communication, e.g Television H04N 13/0203 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 09572815 | Zuo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (Memphis, Tennessee) |
| ASSIGNEE(S) | St. Jude Children's Research Hospital (Memphis, Tennessee) |
| INVENTOR(S) | Jian Zuo (Memphis, Tennessee); Taosheng Chen (Germantown, Tennessee); Brandon Walters (Memphis, Tennessee); Bryan Kuo (Memphis, Tennessee); Bradley Walters (Memphis, Tennessee) |
| ABSTRACT | In one aspect, the invention relates to pharmaceutical compositions comprising agents that activate the expression of Atoh1, or pharmaceutically acceptable salts, solvates, or polymorphs thereof; and agents that inhibit the expression of p27Kip1, or pharmaceutically acceptable salts, solvates, or polymorphs thereof, which are useful for inducing the formation of cochlear hair cells; and methods of treating hearing impairments or disorders using the compositions. In one aspect, the invention relates to pharmaceutical compositions comprising β-catenin; and agents that activate the expression of Atoh1, or pharmaceutically acceptable salts, solvates, or polymorphs thereof. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Saturday, March 15, 2014 |
| APPL NO | 14/774597 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/44 (20130101) A61K 31/55 (20130101) Original (OR) Class A61K 31/222 (20130101) A61K 31/4418 (20130101) A61K 35/12 (20130101) A61K 38/17 (20130101) A61K 38/1703 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0602 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572834 | Tour et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James M. Tour (Bellaire, Texas); Jacob Berlin (Monrovia, California); Daniela Marcano (Houston, Texas); Ashley Leonard (Houston, Texas); Thomas A. Kent (Houston, Texas); Robia G. Pautler (Pearland, Texas); Brittany Bitner (Dallas Center, Iowa); Taeko Inoue (Pasadena, Texas) |
| ASSIGNEE(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas); BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | James M. Tour (Bellaire, Texas); Jacob Berlin (Monrovia, California); Daniela Marcano (Houston, Texas); Ashley Leonard (Houston, Texas); Thomas A. Kent (Houston, Texas); Robia G. Pautler (Pearland, Texas); Brittany Bitner (Dallas Center, Iowa); Taeko Inoue (Pasadena, Texas) |
| ABSTRACT | In some embodiments, the present invention provides methods of treating oxidative stress in a subject by administering a therapeutic composition to the subject. In some embodiments, the therapeutic composition comprises a carbon nanomaterial with anti-oxidant activity. In some embodiments, the anti-oxidant activity of the carbon nanomaterial corresponds to ORAC values between about 200 to about 15,000. In some embodiments, the administered carbon nanomaterials include at least one of single-walled nanotubes, double-walled nanotubes, triple-walled nanotubes, multi-walled nanotubes, ultra-short nanotubes, graphene, graphene nanoribbons, graphite, graphite oxide nanoribbons, carbon black, oxidized carbon black, hydrophilic carbon clusters, and combinations thereof. In some embodiments, the carbon nanomaterial is an ultra-short single-walled nanotube that is functionalized with a plurality of solubilizing groups. In some embodiments, the carbon nanomaterial is a polyethylene glycol functionalized hydrophilic carbon cluster (PEG-HCC). In some embodiments, the administered therapeutic compositions of the present invention may also include an active agent or targeting agent associated with the carbon nanomaterial. Additional embodiments of the present invention pertain to the aforementioned carbon nanomaterial compositions for treating oxidative stress. |
| FILED | Thursday, April 26, 2012 |
| APPL NO | 14/114007 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 33/44 (20130101) Original (OR) Class A61K 33/44 (20130101) A61K 45/06 (20130101) A61K 47/48215 (20130101) A61K 47/48869 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572835 | Spencer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| ASSIGNEE(S) | BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | David Spencer (Houston, Texas); Brent Hanks (Houston, Texas); Kevin Slawin (Houston, Texas) |
| ABSTRACT | The present invention is directed to a composition and method which to treat diseases and to enhance a regulated immune response. More particularly, the present invention is drawn to compositions that are based on dendritic cells modified to express an inducible form of a co-stimulatory polypeptide. |
| FILED | Tuesday, March 10, 2015 |
| APPL NO | 14/643989 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/15 (20130101) Original (OR) Class A61K 38/177 (20130101) A61K 38/1774 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) A61K 2039/53 (20130101) A61K 2039/5154 (20130101) A61K 2039/5156 (20130101) A61K 2039/55516 (20130101) Peptides C07K 14/70578 (20130101) C07K 2319/033 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/10 (20130101) C12N 5/16 (20130101) C12N 9/90 (20130101) C12N 9/485 (20130101) C12N 2710/10043 (20130101) Enzymes C12Y 304/17021 (20130101) C12Y 502/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573125 | Weitekamp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Raymond Weitekamp (Glendale, California); Robert H. Grubbs (South Pasadena, California) |
| ABSTRACT | An efficient method for the preparation of backbone-substituted imidazolinium salts for use as N-heterocyclic carbene ligands, e.g., for organometallic catalysts is provided. These functionalized N-heterocyclic carbene ligands are used to prepare solid-supported catalysts, e.g., for olefin metathesis. |
| FILED | Wednesday, June 26, 2013 |
| APPL NO | 13/928155 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/22 (20130101) Original (OR) Class B01J 31/0259 (20130101) B01J 31/1625 (20130101) B01J 31/2273 (20130101) B01J 2231/543 (20130101) B01J 2531/17 (20130101) B01J 2531/18 (20130101) B01J 2531/821 (20130101) B01J 2540/64 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/65062 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/582 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573284 | Thwing et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southwest Research Institute (San Antonio, Texas) |
| ASSIGNEE(S) | SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas) |
| INVENTOR(S) | Clinton J. Thwing (Bulverde, Texas); Don E. Mahoney (San Antonio, Texas) |
| ABSTRACT | A method and apparatus for forming a starter notch along the length of a work-piece for subsequent fatigue testing. The starter notch is formed with a cutting wire such that it will promote fatigue-cracking in the work-piece in one defined direction and avoids cracking in directions other than the length direction of the starter notch. Improved fatigue-testing analysis may therefore be realized. |
| FILED | Wednesday, January 15, 2014 |
| APPL NO | 14/156057 |
| ART UNIT | 3724 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Planing; Slotting; Shearing; Broaching; Sawing; Filing; Scraping; Like Operations for Working Metal by Removing Material, Not Otherwise Provided for B23D 57/003 (20130101) B23D 57/0007 (20130101) Cutting; Details Common to Machines for Perforating, Punching, Cutting-out, Stamping-out or Severing B26D 1/547 (20130101) B26D 3/14 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 83/0304 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573311 | Mott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David R. Mott (Burke, Virginia); Peter B. Howell, Jr. (Gaithersburg, Maryland); Frances S. Ligler (Potomac, Maryland); Stephanie Fertig (Springfield, Virginia); Aron Bobrowski (Miami, Florida) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | David R. Mott (Burke, Virginia); Peter B. Howell, Jr. (Gaithersburg, Maryland); Frances S. Ligler (Potomac, Maryland); Stephanie Fertig (Springfield, Virginia); Aron Bobrowski (Miami, Florida) |
| ABSTRACT | A sheath flow system having a channel with first and second fluid transporting structures located on opposing surfaces facing one another across the channel in the top and bottom surfaces of the channel situated so as to transport the sheath fluid laterally across the channel to provide sheath fluid fully surrounding the core solution. At the point of introduction into the channel, the sheath fluid and core solutions flow side by side within the channel or the core solution may be bounded on either side by the sheath fluid. The system is functional over a broad channel size range and with liquids of high or low viscosity. The design can be readily incorporated into microfluidic chips without the need for special manufacturing protocols. |
| FILED | Thursday, December 27, 2012 |
| APPL NO | 13/728651 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/502746 (20130101) B01L 3/502776 (20130101) B01L 2400/084 (20130101) B01L 2400/0487 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 47/0014 (20130101) B29C 47/30 (20130101) B29C 47/065 (20130101) Original (OR) Class B29C 47/0816 (20130101) Optical Elements, Systems, or Apparatus G02B 6/032 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49 (20150115) Y10T 137/0318 (20150401) Y10T 137/0324 (20150401) Y10T 137/0329 (20150401) Y10T 137/0335 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573638 | Won |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chikyung Won (Tewksbury, Massachusetts) |
| ASSIGNEE(S) | IROBOT DEFENSE HOLDINGS, INC. (Bedford, Massachusetts) |
| INVENTOR(S) | Chikyung Won (Tewksbury, Massachusetts) |
| ABSTRACT | An articulated tracked vehicle that has a main section, which includes a main frame, and a forward section. The main frame has two sides and a front end, and includes a pair of parallel main tracks. Each main track includes a flexible continuous belt coupled to a corresponding side of the main frame. The forward section includes an elongated arm. One end of the arm is pivotally coupled to the main frame near the forward end of the main frame about a transverse axis that is generally perpendicular to the sides of the main frame. The arm has a length sufficiently long to allow the forward section to extend below the main section in at least some degrees of rotation of the arm, and a length shorter than the length of the main section. The center of mass of the main section is located forward of the rearmost point reached by the end of the arm in its pivoting about the transverse axis. The main section is contained within the volume defined by the main tracks and is symmetrical about a horizontal plane, thereby allowing inverted operation of the robot. |
| FILED | Monday, August 06, 2007 |
| APPL NO | 11/834290 |
| ART UNIT | 3611 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 5/005 (20130101) B25J 11/0025 (20130101) Motor Vehicles; Trailers B62D 55/12 (20130101) B62D 55/14 (20130101) B62D 55/065 (20130101) B62D 55/075 (20130101) B62D 55/244 (20130101) B62D 55/0655 (20130101) Original (OR) Class Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 180/901 (20130101) Y10S 280/901 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573664 | Wiggins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Adaptive Methods, Inc. (Rockville, Maryland) |
| ASSIGNEE(S) | Adaptive Methods, Inc. (Rockville, Maryland) |
| INVENTOR(S) | Jim Wiggins (Thurmont, Maryland); Conrad Zeglin (Rockville, Maryland); Walter Allensworth (Poolesville, Maryland) |
| ABSTRACT | A variable drag area tow system including a tow cable, and a variable drag area device having a variable projected area, the variable drag area device is configured to have a smaller projected area as the velocity of the variable drag area device with respect to a fluid increases. A method of maintaining tension on a tow cable, the method including deploying at a first velocity a variable drag area device having a variable projected area, increasing the first velocity to a second velocity, and decreasing the projected area of the variable drag area device as the first velocity is increased to the second velocity. |
| FILED | Monday, July 29, 2013 |
| APPL NO | 13/953124 |
| ART UNIT | 3617 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Ships or Other Waterborne Vessels; Equipment for Shipping B63B 21/66 (20130101) Original (OR) Class B63B 21/663 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 3/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573691 | Sadeck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | James Sadeck (East Freetown, Massachusetts); Hamid Johari (Thousand Oaks, California) |
| ABSTRACT | A ram air canopy includes a top skin, a bottom skin, a plurality of ribs between the top skin and the bottom skin forming a plurality of cells. A leading edge of a cell includes an opening to allow air to enter the cell. A glide vent is disposed in the top skin to allow air the exit the cell. |
| FILED | Thursday, July 16, 2015 |
| APPL NO | 14/800836 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 17/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573692 | Costello et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Earthly Dynamics, LLC (Atlanta, Georgia) |
| ASSIGNEE(S) | Earthly Dynamics, LLC (Atlanta, Georgia) |
| INVENTOR(S) | Mark F Costello (Atlanta, Georgia); Michael Brian Ward (Atlanta, Georgia); Edward James Scheuermann (Atlanta, Georgia); Keith Bergeron (Framingham, Massachusetts); Michael Wayne Shurtliff (Ashland, Massachusetts); Gregory Michael Noetscher (Shrewsbury, Massachusetts) |
| ABSTRACT | A system is described to control the flight path of a parafoil. The physical control mechanism is a series of actuators embedded within the parafoil canopy that open a series of meshed venting systems in the upper surface of the parafoil canopy. Opening and closing the meshed venting system changes the forces and moments acting on the parafoil canopy in a consistent manner such that it can be used for flight control. The meshed venting system includes an internal sealing flap and a mesh member. |
| FILED | Tuesday, May 12, 2015 |
| APPL NO | 14/709606 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 17/18 (20130101) B64D 17/22 (20130101) B64D 17/025 (20130101) B64D 17/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573856 | Currano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Luke M. Currano (Columbia, Maryland); Madan Dubey (South River, New Jersey); Ronald G. Polcawich (Derwood, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Luke M. Currano (Columbia, Maryland); Madan Dubey (South River, New Jersey); Ronald G. Polcawich (Derwood, Maryland) |
| ABSTRACT | A micro-explosive material is provided. The micro-explosive material can include a carbon nanotube and a solid oxidizer attached to the carbon nanotube. The carbon nanotube with the solid oxidizer attached thereto is operable to burn per an exothermic chemical reaction between the carbon nanotube and the solid oxidizer such that a controlled burn and/or an explosive burn is provided. The micro-explosive material can be used as a heat generator, a gas generator, a micro-thruster, a primer for use with a larger explosive material, and the like. |
| FILED | Tuesday, February 14, 2012 |
| APPL NO | 13/372720 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 43/00 (20130101) Original (OR) Class C06B 45/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573857 | Reid et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida); The Texas A and M University System (College Station, Texas) |
| INVENTOR(S) | David L. Reid (Orlando, Florida); Sudipta Seal (Orlando, Florida); Eric Petersen (College Station, Texas) |
| ABSTRACT | A method of forming composite materials includes mixing a first metal precursor with a chelating agent to form a first metal-chelate complex. The first metal-chelate complex is added to a polymer binder having terminating hydroxyl groups to form a polymer binder-first metal-chelate. The polymer binder first metal-chelate complex is mixed with an aluminum precursor. The aluminum precursor decomposes forming aluminum nanoparticles dispersed in a continuous phase material having metallic aluminum cores. At least one of the first metal-chelate complex and the first metal is dissolved in the continuous phase. The aluminum nanoparticles can have a passivating coating layer thereon provided by the polymer binder, or can have a passivating coating layer formed by including an epoxide, alcohol, carboxylic acid, or amine in the adding that forms passivating compound(s) which add further protection that can provide complete protection from oxidation of the metallic aluminum cores by air. |
| FILED | Tuesday, March 12, 2013 |
| APPL NO | 13/797044 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0022 (20130101) B22F 1/0062 (20130101) B22F 2001/0029 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 45/08 (20130101) Original (OR) Class C06B 45/10 (20130101) Means for Generating Smoke or Mist; Gas-attack Compositions; Generation of Gas for Blasting or Propulsion C06D 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574113 | Crosby et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alfred J. Crosby (Amherst, Massachusetts); Michael Bartlett (Sunderland, Massachusetts); Andrew B. Croll (West Fargo, North Dakota); Daniel J. King (Sunderland, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alfred J. Crosby (Amherst, Massachusetts); Michael Bartlett (Sunderland, Massachusetts); Andrew B. Croll (West Fargo, North Dakota); Daniel J. King (Sunderland, Massachusetts) |
| ABSTRACT | The invention provides novel devices, systems, designs, materials and fabrication methods that enable high-load capacity, easy release, and suitable for extended/repeated use in a variety of applications. |
| FILED | Friday, October 21, 2011 |
| APPL NO | 13/878405 |
| ART UNIT | 1781 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/20 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 7/045 (20130101) C09J 7/048 (20130101) Original (OR) Class C09J 2201/28 (20130101) C09J 2201/622 (20130101) C09J 2400/263 (20130101) C09J 2433/00 (20130101) C09J 2475/00 (20130101) C09J 2483/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2481 (20150115) Y10T 428/2848 (20150115) Y10T 428/24612 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574134 | Wood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanessa Wood (Cambridge, Massachusetts); Matthew J. Panzer (Cambridge, Massachusetts); Jonathan E. Halpert (McClean, Virginia); Moungi G. Bawendi (Cambridge, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Vanessa Wood (Cambridge, Massachusetts); Matthew J. Panzer (Cambridge, Massachusetts); Jonathan E. Halpert (McClean, Virginia); Moungi G. Bawendi (Cambridge, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts) |
| ABSTRACT | A voltage driven light emitting device includes an electroluminescent material and semiconductor nanocrystals, luminescent organic small molecules, mixtures of emissive species molecules, or conductive polymers. The semiconductor nanocrystals, luminescent organic small molecules, mixtures of emissive species molecules, or conductive polymers emit light. The semiconductor nanocrystals, luminescent organic small molecules, mixtures of emissive species molecules, or conductive polymers can be doped to provide desired emission characteristics. Devices that share a substrate and emit more than one color may be conveniently made. |
| FILED | Friday, May 07, 2010 |
| APPL NO | 12/776126 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/565 (20130101) Original (OR) Class Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/14 (20130101) H05B 33/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574232 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Crystal Han (Stanford, California); Juan G. Santiago (Stanford, California); Viktor Shkolnikov (Chatsworth, California) |
| ABSTRACT | Devices and methods for controlling reversible chemical reactions at solid-liquid interfaces are disclosed. In particular, the invention relates to a method of increasing reaction rates by concentrating a target molecule in a liquid phase in the region of a reactant or ligand immobilized on a solid followed by removal of the liquid phase and replacement with an immiscible phase, such as an immiscible gas or liquid to impede the reverse reaction. Devices for performing this method to increase the rates and degree of completion of kinetically limited ligand binding or nucleic acid hybridization reactions in affinity chromatography and microarray applications are also disclosed. |
| FILED | Tuesday, February 24, 2015 |
| APPL NO | 14/630623 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 1/22 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6832 (20130101) C12Q 1/6837 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/27 (20130101) G01N 27/447 (20130101) G01N 27/44704 (20130101) G01N 27/44791 (20130101) G01N 27/44795 (20130101) G01N 30/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574263 | Verbeck, IV et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of North Texas (Denton, Texas) |
| ASSIGNEE(S) | University of North Texas (Denton, Texas) |
| INVENTOR(S) | Guido Fridolin Verbeck, IV (Plano, Texas); Stephen Davila (Odessa, Texas) |
| ABSTRACT | A soft-landing (SL) instrument for depositing ions onto substrates using a laser ablation source is described herein. The instrument of the instant invention is designed with a custom drift tube and a split-ring ion optic for the isolation of selected ions. The drift tube allows for the separation and thermalization of ions formed after laser ablation through collisions with an inert bath gas that allow the ions to be landed at energies below 1 eV onto substrates. The split-ring ion optic is capable of directing ions toward the detector or a landing substrate for selected components. The inventors further performed atomic force microscopy (AFM) and drift tube measurements to characterize the performance characteristics of the instrument. |
| FILED | Tuesday, November 12, 2013 |
| APPL NO | 14/077911 |
| ART UNIT | 1718 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/112 (20130101) Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/04 (20130101) C23C 14/12 (20130101) C23C 14/28 (20130101) C23C 14/54 (20130101) C23C 14/221 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574575 | Graves et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Rolls-Royce Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Charles B. Graves (Avon, Indiana); Stuart M. Bloom (Indianapolis, Indiana); Donald M. Wicksall (New Palestine, Indiana); Jacob E. Determan (Indianapolis, Indiana) |
| ABSTRACT | A diffuser is disclosed that includes a splitter having a blunt forebody useful in re-starting a boundary layer. The blunt forebody can be used to create a static pressure bow wave and interaction with a passing fluid stream that reduces a thickness of boundary layer formed on an opposing wall. The re-start in boundary layer can be used in a way that allows an upstream portion of the diffuser to be sized approaching a separation limit and a downstream portion of the diffuser to also be sized approaching a separation limit. In some forms the passages split by the blunt forebody can be sized relative to each other to balance flow between the branches. |
| FILED | Friday, December 13, 2013 |
| APPL NO | 14/105572 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive-displacement Pumps F04D 29/44 (20130101) F04D 29/54 (20130101) F04D 29/547 (20130101) Original (OR) Class F04D 29/681 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574801 | Seletskiy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Denis V. Seletskiy (Albuquerque, New Mexico); Richard Epstein (Santa Fe, New Mexico); Markus P. Hehlen (Los Alamos, New Mexico); Mansoor Sheik-Bahae (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Denis V. Seletskiy (Albuquerque, New Mexico); Richard Epstein (Santa Fe, New Mexico); Markus P. Hehlen (Los Alamos, New Mexico); Mansoor Sheik-Bahae (Albuquerque, New Mexico) |
| ABSTRACT | A method and device for cooling electronics is disclosed. The device includes a doped crystal configured to resonate at a Stark manifold resonance capable of cooling the crystal to a temperature of from about 110K to about 170K. The crystal host resonates in response to input from an excitation laser tuned to exploit the Stark manifold resonance corresponding to the cooling of the crystal. |
| FILED | Thursday, December 23, 2010 |
| APPL NO | 12/977465 |
| ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) Original (OR) Class F25B 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574851 | Weiland |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Christopher J. Weiland (King George, Virginia) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Christopher J. Weiland (King George, Virginia) |
| ABSTRACT | A method is provided for aligning a gun barrel. The method includes disposing a signal transmitter at the barrel's muzzle, distributing sensors around the barrel to receive the muzzle's signal, calculating the muzzle's coordinate position based on the signal, aiming an electro-optical sensor at a target to determine a miss distance, and calibrating the gun barrel based on the electro-optical sensor based on the miss distance. |
| FILED | Friday, December 11, 2015 |
| APPL NO | 14/967003 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Weapon Sights; Aiming F41G 3/326 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574966 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Haiying Huang (Arlington, Texas); Jung-Chih Chiao (Grand Prairie, Texas); Ronald L. Carter (Arlington, Texas); Uday Shankar Tata (Arlington, Texas) |
| ABSTRACT | An apparatus and method is provided for monitoring a condition of a structure using a passive wireless antenna sensor having a known resonant frequency when mounted on the structure. A signal is transmitted with sweeping frequencies around a known resonant frequency to the passive wireless antenna sensor. A signal is received from the passive wireless antenna sensor and a resonant frequency of the passive wireless antenna sensor is determined based on the received signal. The determined resonant frequency is then compared to the known resonant frequency, whereby a change in the resonant frequency indicates a change in the condition of the structure. |
| FILED | Thursday, October 02, 2014 |
| APPL NO | 14/504933 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 5/0033 (20130101) G01M 5/0083 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575015 | Sung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yongjin Sung (Boston, Massachusetts); Rajiv Gupta (Wayland, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Yongjin Sung (Boston, Massachusetts); Rajiv Gupta (Wayland, Massachusetts) |
| ABSTRACT | Systems and methods for performing x-ray phase-contrast imaging using a conventional x-ray source and detector are provided. An array of x-ray focusing elements it provided and used to focus x-ray onto a pattern of multiple different focal spots. When an object is introduced into the beam path, the focal spots will be displaced based on the x-rays being refracted by the object. A refraction angle map is produced and used to generate a phase contrast image, such as an image that indicates the electron density distribution in the object. Multi-spectral imaging can be achieved by utilizing the chromatic aberration of the array of x-ray focusing elements and sweeping the detector through different focal planes associated with different x-ray energy levels or sweeping the peak voltage of the x-ray source for a fixed object-to-detector distance. |
| FILED | Monday, March 30, 2015 |
| APPL NO | 14/673304 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/04 (20130101) Original (OR) Class G01N 23/20075 (20130101) G01N 2223/303 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/06 (20130101) G21K 2201/067 (20130101) G21K 2207/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575046 | Laquidara et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Joseph M. Laquidara (Westwood, New Jersey); Christopher D. Applegate (Andover, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Joseph M. Laquidara (Westwood, New Jersey); Christopher D. Applegate (Andover, New Jersey) |
| ABSTRACT | Explosive reagent detecting compositions are provided for detecting explosives containing chlorate and hydrogen peroxide. Such compositions include Ru-EDTA complexes, binuclear aromatic hydroxyl (BAH) and an optional lanthanide salt. Embodiments of these compositions may be combined with a compact and flexible packaging as an easy-to-use kit for detecting the presence of explosives. |
| FILED | Thursday, November 05, 2015 |
| APPL NO | 14/933657 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 31/22 (20130101) G01N 33/0039 (20130101) G01N 33/227 (20130101) Original (OR) Class G01N 33/582 (20130101) G01N 33/2882 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575144 | Kornack et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Thomas Whitmore Kornack (Princeton, New Jersey); Elizabeth Lee Foley (Princeton, New Jersey) |
| ASSIGNEE(S) | TWINLEAF LLC (Princeton, New Jersey) |
| INVENTOR(S) | Thomas Whitmore Kornack (Princeton, New Jersey); Elizabeth Lee Foley (Princeton, New Jersey) |
| ABSTRACT | A compact, high-sensitivity magnetometer, including: an optical interface to accept a linearly polarized first light; a pump light source to produce a circularly polarized pump light; a vapor cell comprising a sealed vessel containing an alkali-metal gas, a first input port to receive the first light, a second input port to accept the pump light from a direction perpendicular to the first light, and an output port configured to produce a second light; an electromagnetic source configured to apply an electromagnetic field to the vapor cell at a direction perpendicular to the first light and the pump light; a second linear polarizer, having an axis of polarization perpendicular to the first light, the second polarizer configured to receive the second light and to produce a third light; and a photodetector configured to receive the third light, to produce an intensity measurement of the third light. |
| FILED | Tuesday, October 15, 2013 |
| APPL NO | 14/054746 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575251 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oracle International Corporation (Redwood City, California) |
| ASSIGNEE(S) | ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California) |
| INVENTOR(S) | Jin-Hyoung Lee (San Diego, California); Ivan Shubin (San Diego, California); Xuezhe Zheng (San Diego, California); Ashok V. Krishnamoorthy (San Diego, California) |
| ABSTRACT | A standard-CMOS-process-compatible optical mode converter transitions an optical mode size using a series of adjacent regions having different optical mode sizes. In particular, in a partial-slab-mode region, which is adjacent to an initial rib-optical-waveguide-mode region, a width of a slab portion of the rib-type optical waveguide decreases and a width of a rib portion of the rib-type optical waveguide decreases to a first minimum tip size. Then, in a slab-mode region, which is adjacent to the partial-slab-mode region, the width of the slab portion decreases to a second minimum tip size. In addition, a dielectric layer is disposed over the slab portion, the rib portion and the BOX layer in the partial-slab-mode region, the slab portion and the BOX layer in the slab-mode region, and the BOX layer in a released-mode region that is adjacent to the slab-mode region and that does not include the semiconductor layer. |
| FILED | Tuesday, August 11, 2015 |
| APPL NO | 14/823954 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/14 (20130101) Original (OR) Class G02B 6/1228 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575256 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oracle International Corporation (Redwood Shores, California) |
| ASSIGNEE(S) | ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California) |
| INVENTOR(S) | Guoliang Li (San Diego, California); Xuezhe Zheng (San Diego, California); Ying Luo (San Diego, California); Ashok V. Krishnamoorthy (San Deigo, California) |
| ABSTRACT | An optical device includes an optical reflector based on a coupled-loopback optical waveguide. In particular, an input port, an output port and an optical loop in arms of the optical reflector are optically coupled to a directional coupler. The directional coupler evanescently couples an optical signal between the arms. For example, the directional coupler may include: a multimode interference coupler and/or a Mach-Zehnder Interferometer (MZI). Moreover, destructive interference during the evanescent coupling determines the reflection and transmission power coefficients of the optical reflector. |
| FILED | Tuesday, May 24, 2016 |
| APPL NO | 15/163591 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) G02B 6/293 (20130101) G02B 6/12007 (20130101) G02B 6/29331 (20130101) G02B 6/29335 (20130101) G02B 6/29338 (20130101) G02B 6/29343 (20130101) G02B 6/29344 (20130101) G02B 6/29352 (20130101) G02B 6/29389 (20130101) Original (OR) Class G02B 6/29395 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/0147 (20130101) G02F 1/225 (20130101) G02F 1/2257 (20130101) G02F 2001/212 (20130101) G02F 2001/217 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/18 (20130101) H01S 5/50 (20130101) H01S 5/141 (20130101) H01S 5/0265 (20130101) H01S 5/2027 (20130101) H01S 5/02252 (20130101) H01S 5/3013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575270 | Sharapov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ORACLE INTERNATIONAL CORPORATION (Redwood City, California) |
| ASSIGNEE(S) | ORACLE INTERNATIONAL CORPORATION (Redwood Shores, California) |
| INVENTOR(S) | Ilya A. Sharapov (Palo Alto, California); Ashok V. Krishnamoorthy (San Diego, California); John E. Cunningham (San Diego, California); Xuehze Zheng (San Diego, California); Brian W. O'Krafka (Austin, Texas); Ronald Ho (Mountain View, California) |
| ABSTRACT | Embodiments of a system that includes an array of chip modules (CMs) is described. In this system, a given CM in the array includes a semiconductor die that is configured to communicate data signals with one or more adjacent CMs through electromagnetic proximity communication using proximity connectors. Note that the proximity connectors are proximate to a surface of the semiconductor die. Moreover, the given CM is configured to communicate optical signals with other CMs through an optical signal path using optical communication, and the optical signals are encoded using wavelength-division multiplexing (WDM). |
| FILED | Monday, October 22, 2012 |
| APPL NO | 13/657722 |
| ART UNIT | 2637 — Optical Communications |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/43 (20130101) Original (OR) Class G02B 6/3897 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/48 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) Multiplex Communication H04J 14/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575307 | Xi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Ning Xi (Okemos, Michigan); Bo Song (East Lansing, Michigan); Jianguo Zhao (East Lansing, Michigan); Wai Chiu King Lai (East Lansing, Michigan) |
| ABSTRACT | Compressive sensing based video rate imaging techniques are presented. Rather than scan the entire image, the imaging system only scans part of the topography of the sample as a compressed scan. After the data has been collected, an algorithm for image reconstruction is applied for recovering the image. Because compressive sensing is used, the imaging rate is increased from several minutes per frame to seconds per frame. Non-vector space control techniques are also presented. No-vector space control use image or compressive data as the input and feedback to generate a closed-loop motion control. Compressive sensing technique provides an efficient data reduction method to retain the essential information in the original image. The non-vector space control method can be used as motion control method with compressive feedback without or with noise. |
| FILED | Friday, March 15, 2013 |
| APPL NO | 14/384608 |
| ART UNIT | 2482 — Recording and Compression |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 10/06 (20130101) G01Q 30/04 (20130101) Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) Original (OR) Class Image Data Processing or Generation, in General G06T 1/0007 (20130101) G06T 1/0014 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575325 | Chann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Bien Chann (Merrimack, New Hampshire); Tso Yee Fan (Belmont, Massachusetts); Antonio Sanchez-Rubio (Lexington, Massachusetts) |
| ABSTRACT | A method and apparatus for two-dimensional wavelength beam combining of laser sources. In one example, an external cavity multi-wavelength laser includes an array of laser emitters each producing an optical beam having a specified wavelength, a grating stack comprising a plurality of first-order diffraction gratings arranged linearly in a first dimension, and a dispersive element. The laser further includes a cylindrical telescope that images the optical beams from the array of laser emitters onto the grating stack. A first cylindrical transform lens spatially overlaps the optical beams in a second dimension forming a first region of overlap at the grating stack. A second cylindrical transform lens spatially overlaps the optical beams from the grating stack in the first dimension forming a second region of overlap at the dispersive element. The dispersive element transmits a multi-wavelength output beam comprising the spatially overlapped optical beams from the array of laser emitters. |
| FILED | Friday, December 20, 2013 |
| APPL NO | 14/136601 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/1819 (20130101) G02B 19/0014 (20130101) G02B 19/0057 (20130101) G02B 27/0944 (20130101) G02B 27/0966 (20130101) G02B 27/1006 (20130101) Original (OR) Class G02B 27/1093 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/4012 (20130101) H01S 5/4025 (20130101) H01S 5/4087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575550 | Oiler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jonathon Keith Oiler (San Diego, California); Andrew Michael Higier (San Diego, California); Daniel Carl Grady (La Jolla, California) |
| ABSTRACT | A method for coordinating operation of an off-grid, hybrid power system and an information technology (IT) system comprising the following steps: powering the IT system with the off-grid, hybrid power system according to a power generation management scheme designed to maximize fuel savings, wherein the hybrid power system comprises a generator and an electrical energy storage source; monitoring tasks performed by the IT system with a processor; determining which component of the hybrid power system is currently powering the IT system; and dynamically changing the tasks performed by the IT system depending on which component of the hybrid power system is currently powering the IT system such that the IT system only performs high priority tasks when the energy storage source is powering the IT system and such that a queue of low priority tasks are held in abeyance until the generator is powering the IT system. |
| FILED | Thursday, September 17, 2015 |
| APPL NO | 14/857356 |
| ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 1/329 (20130101) Original (OR) Class G06F 1/3228 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09576031 | Aggarwal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Charu Aggarwal (Yorktowne Heights, New York); Yanjie Fu (Newark, New Jersey); Srinivasan Parthasarathy (Yonkers, New York); Deepak Turaga (Elmsford, New York) |
| ABSTRACT | An automated outlier detection system implements an unsupervised set of processes to determine feature subspaces from a dataset; determine candidate exploratory actions, where each candidate exploratory action is a specific combination of a feature subspace and a parameterized instance of an outlier detection algorithm; and identify a set of optimal exploratory actions to recommend for execution on the dataset from among the candidate exploratory actions. Outlier scores obtained as a result of execution of the set of optimal exploratory actions are processed to obtain one or more outlier views such that each outlier view represents a consistent characterization of outliers by each optimal exploratory action corresponding to that outlier view. |
| FILED | Monday, February 08, 2016 |
| APPL NO | 15/018016 |
| ART UNIT | 2155 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 17/3053 (20130101) Original (OR) Class G06F 17/30572 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09576127 | Stolfo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Salvatore J. Stolfo (Ridgewood, New Jersey); Wei-Jen Li (Rego Park, New York); Angelos D. Keromytis (New York, New York); Elli Androulaki (New York, New York) |
| ABSTRACT | Methods, media, and systems for detecting attack are provided. In some embodiments, the methods include: comparing at least part of a document to a static detection model; determining whether attacking code is included in the document based on the comparison of the document to the static detection model; executing at least part of the document; determining whether attacking code is included in the document based on the execution of the at least part of the document; and if attacking code is determined to be included in the document based on at least one of the comparison of the document to the static detection model and the execution of the at least part of the document, reporting the presence of an attack. In some embodiments, the methods include: selecting a data segment in at least one portion of an electronic document; determining whether the arbitrarily selected data segment can be altered without causing the electronic document to result in an error when processed by a corresponding program; in response to determining that the arbitrarily selected data segment can be altered, arbitrarily altering the data segment in the at least one portion of the electronic document to produce an altered electronic document; and determining whether the corresponding program produces an error state when the altered electronic document is processed by the corresponding program. |
| FILED | Monday, July 21, 2014 |
| APPL NO | 14/336649 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/50 (20130101) Original (OR) Class G06F 21/56 (20130101) G06F 21/562 (20130101) G06F 21/566 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09576214 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Lei Zhang (Torrance, California); Deepak Khosla (Camarillo, California); Yang Chen (Westlake Village, California) |
| ABSTRACT | Described is system for object recognition from moving platforms. The system receives a video captured from a moving platform as input. The video is processed with a static object detection module to detect static objects in the video, resulting in a set of static object detections. The video is also processed with a moving object detection module to detect moving objects in the video, resulting in a set of moving object detections. The set of static object detections and the set of moving object detections are fused, resulting in a set of detected objects. The set of detected objects are classified with an object classification module, resulting in a set of recognized objects that are then output. |
| FILED | Wednesday, October 01, 2014 |
| APPL NO | 14/504248 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00744 (20130101) G06K 9/4614 (20130101) Original (OR) Class G06K 9/6257 (20130101) G06K 9/6267 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09576570 | Precoda et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kristin Precoda (Mountain View, California); Horacio Franco (Menlo Park, California); Jing Zheng (Sunnyvale, California); Michael Frandsen (Helena, Montana); Victor Abrash (Montara, California); Murat Akbacak (Palo Alto, California); Andreas Stolcke (Berkeley, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | Kristin Precoda (Mountain View, California); Horacio Franco (Menlo Park, California); Jing Zheng (Sunnyvale, California); Michael Frandsen (Helena, Montana); Victor Abrash (Montara, California); Murat Akbacak (Palo Alto, California); Andreas Stolcke (Berkeley, California) |
| ABSTRACT | The present invention relates to a method and apparatus for adding new vocabulary to interactive translation and dialog systems. In one embodiment, a method for adding a new word to a vocabulary of an interactive dialog includes receiving an input signal that includes at least one word not currently in the vocabulary, inserting the word into a dynamic component of a search graph associated with the vocabulary, and compiling the dynamic component independently of a permanent component of the search graph to produce a new sub-grammar, where the permanent component comprises a plurality of words that are permanently part of the search graph. |
| FILED | Friday, July 30, 2010 |
| APPL NO | 12/847826 |
| ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/06 (20130101) Original (OR) Class G10L 15/063 (20130101) G10L 15/193 (20130101) G10L 2015/0635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09576631 | Buhrman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Robert A. Buhrman (Ithaca, New York); Luqiao Liu (Ithaca, New York); Daniel C. Ralph (Ithaca, New York); Chi-Feng Pai (Ithaca, New York) |
| ABSTRACT | An ST-MRAM structure, a method for fabricating the ST-MRAM structure and a method for operating an ST-MRAM device that results from the ST-MRAM structure each utilize a spin Hall effect base layer that contacts a magnetic free layer and effects a magnetic moment switching within the magnetic free layer as a result of a lateral switching current within the spin Hall effect base layer. This resulting ST-MRAM device uses an independent sense current and sense voltage through a magnetoresistive stack that includes a pinned layer, a non-magnetic spacer layer and the magnetic free layer which contacts the spin Hall effect base layer. Desirable non-magnetic conductor materials for the spin Hall effect base layer include certain types of tantalum materials and tungsten materials that have a spin diffusion length no greater than about five times the thickness of the spin Hall effect base layer and a spin Hall angle at least about 0.05. |
| FILED | Monday, August 10, 2015 |
| APPL NO | 14/822807 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/18 (20130101) G11C 11/161 (20130101) Original (OR) Class G11C 11/1673 (20130101) G11C 11/1675 (20130101) G11C 16/30 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/3254 (20130101) H01F 10/3286 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/04 (20130101) H01L 43/08 (20130101) H01L 43/12 (20130101) H01L 43/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09576725 | Glaser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Niskayuna, New York) |
| INVENTOR(S) | John Stanley Glaser (Schenectady, New York); Joseph Taher Mossoba (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods are disclosed for reducing an interwinding capacitance current in a transformer. In certain embodiments, the transformer includes a coupling winding and a primary winding that encircles a portion of the coupling winding. Additionally, the transformer includes a secondary winding that encircles a portion of the coupling winding. The transformer includes a shield terminal which is electrically coupled to the coupling winding. The shield terminal directs currents, such as interwinding capacitance currents, in the coupling winding to ground. |
| FILED | Friday, December 28, 2012 |
| APPL NO | 13/730332 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/38 (20130101) H01F 27/362 (20130101) Original (OR) Class H01F 2019/085 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/08 (20130101) H02M 2001/0006 (20130101) Pulse Technique H03K 17/567 (20130101) H03K 17/691 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09576889 | Vick |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| INVENTOR(S) | Erik Paul Vick (Raleigh, North Carolina) |
| ABSTRACT | An electronic package may be fabricated by forming a first layer of insulating material on a first substrate such that the first layer covers a contact pad; forming an opening through the first layer to expose the contact pad; forming an un-patterned second layer on the first layer, the second layer including an adhesive having a viscosity less than that of the first layer, wherein a region of the second layer obstructs the contact pad; removing the region to re-expose the contact pad; aligning a second substrate with the first substrate such that a via of the second substrate is aligned with the opening; bonding the first substrate and the second substrate together at the second layer; and forming an interconnect in contact with the contact pad by depositing a conductive material through the via and the opening. |
| FILED | Tuesday, June 25, 2013 |
| APPL NO | 14/408887 |
| ART UNIT | 2895 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02107 (20130101) H01L 21/76898 (20130101) H01L 23/49827 (20130101) Original (OR) Class H01L 24/29 (20130101) H01L 24/83 (20130101) H01L 24/95 (20130101) H01L 25/50 (20130101) H01L 25/162 (20130101) H01L 25/0657 (20130101) H01L 2224/2919 (20130101) H01L 2924/00 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2924/0665 (20130101) H01L 2924/0675 (20130101) H01L 2924/07025 (20130101) H01L 2924/12042 (20130101) H01L 2924/12042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577047 | Chua et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | PALO ALTO RESEARCH CENTER INCORPORATED (Palo Alto, California) |
| INVENTOR(S) | Christopher L. Chua (San Jose, California); Qian Wang (Palo Alto, California); Brent S. Krusor (Fremont, California); JengPing Lu (Fremont, California); Scott J. Limb (Palo Alto, California) |
| ABSTRACT | An article includes a support substrate bonded to heterostructure epitaxial layers that include one or more electronic devices. The support substrate has a bonding surface and the heterostructure epitaxial layers have a surface with the epitaxial growth direction of the heterostructure epitaxial layers towards the surface. The surface of the heterostructure epitaxial layers is bonded at the bonding surface of the support substrate by ion exchange between the surface of the heterostructure epitaxial layers and the bonding surface of the support substrate. |
| FILED | Friday, July 10, 2015 |
| APPL NO | 14/796440 |
| ART UNIT | 2817 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/0254 (20130101) H01L 21/02532 (20130101) H01L 21/02543 (20130101) H01L 21/02546 (20130101) H01L 21/02664 (20130101) H01L 29/205 (20130101) Original (OR) Class H01L 29/267 (20130101) H01L 29/2003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577174 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Xiao Liu (Fairfax, Virginia); Thomas H. Metcalf (Washington, District of Columbia); Daniel R. Queen (Silver Spring, Maryland); Battogtokh Jugdersuren (Arlington, Virginia); Qi Wang (Littleton, Colorado); William Nemeth (Wheat Ridge, Colorado) |
| ABSTRACT | A process for forming a doped nc-Si thin film thermoelectric material. A nc-Si thin film is slowly deposited on a substrate, either by hot-wire CVD (HWCVD) with a controlled H2:SiH4 ratio R=6-10 or by plasma-enhanced (PECVD) with a controlled R=80-100, followed by ion implantation of an n- or p-type dopant and a final annealing step to activate the implanted dopants and to remove amorphous regions. A doped nc-Si thin film thermoelectric material so formed has both a controllable grain size of from a few tens of nm to 3 nm and a controllable dopant distribution and thus can be configured to provide a thermoelectric material having predetermined desired thermal and/or electrical properties. A final annealing step is used to activate the dopants and remove any residual amorphous regions. |
| FILED | Tuesday, September 06, 2016 |
| APPL NO | 15/256764 |
| ART UNIT | 2812 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 35/22 (20130101) H01L 35/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577179 | Gajek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York); The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (Tuscaloosa, Alabama) |
| INVENTOR(S) | Marcin J. Gajek (Cortlandt Manor, New York); Daniel C. Worledge (Cortlandt Manor, New York); William H. Butler (Tuscaloosa, Alabama) |
| ABSTRACT | A magnetic logic cell includes a first electrode portion, a magnetic portion arranged on the first electrode, the magnetic portion including an anti-ferromagnetic material or a ferrimagnetic material, a dielectric portion arranged on the magnetic portion, and a second electrode portion arranged on the dielectric portion. |
| FILED | Thursday, February 07, 2013 |
| APPL NO | 13/761792 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) Original (OR) Class H01L 43/08 (20130101) H01L 43/10 (20130101) H01L 43/12 (20130101) Pulse Technique H03K 19/168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577180 | Gajek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York); The Board of Trustees of the University of Alabama (Tuscaloosa, Alabama) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (Tuscaloosa, Alabama) |
| INVENTOR(S) | Marcin J. Gajek (New York, New York); Daniel C. Worledge (Cortlandt Manor, New York); William H. Butler (Tuscaloosa, Alabama) |
| ABSTRACT | A magnetic logic cell includes a first electrode portion, a magnetic portion arranged on the first electrode, the magnetic portion including an anti-ferromagnetic material or a ferrimagnetic material, a dielectric portion arranged on the magnetic portion, and a second electrode portion arranged on the dielectric portion. |
| FILED | Thursday, January 29, 2015 |
| APPL NO | 14/608348 |
| ART UNIT | 2822 — Semiconductors/Memory |
| CURRENT CPC | Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/002 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) Original (OR) Class H01L 43/08 (20130101) H01L 43/10 (20130101) H01L 43/12 (20130101) Pulse Technique H03K 19/168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577344 | Stambovsky |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of Americ as represented by the Secretary of the Air Force (Washington, District of Columbia) |
| INVENTOR(S) | Daniel W. Stambovsky (New Hartford, New York) |
| ABSTRACT | Apparatus for improving the performance and allowing increased directionality of reflecting-type antenna systems by varying the geometry of the reflecting surface. A reflecting surface is composed of an array of actuated pins which are capable of extending or retracting to alter the overall pattern. An actuator controlling unit has the address of each actuator and is able to extend or retract the pins to the desired degree. The specific pattern which the actuator control unit realizes is determined by the iterative position calculator which utilizes directional inputs from the user and/or inputs from a system which determines the effectiveness of previous pin movements. The apparatus attempts to maximize the received signal by assessing amplitude changes over time and utilizing that information to direct alteration in the reflecting surface for optimal performance. |
| FILED | Wednesday, January 29, 2014 |
| APPL NO | 14/167269 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/1264 (20130101) H01Q 3/01 (20130101) H01Q 15/147 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577401 | Shaw et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Leslie Brandon Shaw (Woodbridge, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Ishwar D. Aggarwal (Charlotte, North Carolina); Daniel J. Gibson (Cheverly, Maryland); Frederic H. Kung (Alexandria, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Leslie Brandon Shaw (Woodbridge, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia); Ishwar D. Aggarwal (Charlotte, North Carolina); Daniel J. Gibson (Cheverly, Maryland); Frederic H. Kung (Alexandria, Virginia) |
| ABSTRACT | Fiber optic amplification in a spectrum of infrared electromagnetic radiation is achieved by creating a chalcogenide photonic crystal fiber (PCF) structure having a radially varying pitch. A chalcogenide PCF system can be tuned during fabrication of the chalcogenide PCF structure, by controlling, the size of the core, the size of the cladding, and the hole size to pitch ratio of the chalcogenide PCF structure and tuned during exercising of the chalcogenide PCF system with pump laser and signal waves, by changing the wavelength of either the pump laser wave or the signal wave, maximization of nonlinear conversion of the chalcogenide PCF, efficient parametric conversion with low peak power pulses of continuous wave laser sources, and minimization of power penalties and minimization of the need for amplification and regeneration of pulse transmissions over the length of the fiber, based on a dispersion factor. |
| FILED | Friday, July 31, 2015 |
| APPL NO | 14/814848 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/02295 (20130101) G02B 6/02342 (20130101) G02B 6/02347 (20130101) G02B 6/02357 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/171 (20130101) H01S 3/1083 (20130101) H01S 3/06741 (20130101) H01S 3/06754 (20130101) Original (OR) Class H01S 3/094096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577600 | Natarajan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Arun S. Natarajan (White Plains, New York); Scott K. Reynolds (Amawalk, New York); Alberto Valdes Garcia (Hartsdale, New York) |
| ABSTRACT | Methods and systems for phase shifting include a hybrid quadrature coupler having an input, an output, and two termination loads. Each termination load includes multiple terminations, each termination having a varactor; and one or more transmission lines separating the terminations. A control module is configured to determine a phase shift and gain to apply to the input and to independently control a capacitance of each varactor such that the output of the hybrid quadrature coupler is shifted by the determined phase shift relative to the input with the determined gain. |
| FILED | Friday, January 11, 2013 |
| APPL NO | 13/739599 |
| ART UNIT | 2649 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Impedance Networks, e.g Resonant Circuits; Resonators H03H 7/20 (20130101) Original (OR) Class H03H 7/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577633 | Swanson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SPAWAR Systems Center Pacific (San Diego, California) |
| ASSIGNEE(S) | The United States of America as represented by Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Paul David Swanson (Santee, California) |
| ABSTRACT | A DC voltage supply provides voltage. A time domain switched inertial capacitive sensor provides a thresholding variable capacitance based on the voltage. A second voltage supply provides a voltage, VDD. A logic inverter circuit has a logic inverter input and a logic inverter output, wherein the logic inverter circuit is supplied with VDD. A third voltage supply provides a second voltage, VCC. A time domain switched inertial capacitive sensor and the capacitor are arranged as a capacitive voltage divider between the DC voltage supply and the logic inverter circuit and so as to provide an input voltage Vin as an input signal to the logic inverter circuit. The logic inverter circuit outputs an output voltage, Vout, based on the input signal. The switch provides a bias voltage, Vbias, to the logic inverter circuit based on Vout such that the input signal is based on Vin and Vbias. |
| FILED | Friday, June 17, 2016 |
| APPL NO | 15/185495 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 17/962 (20130101) Original (OR) Class H03K 2217/960725 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577653 | Buhrman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Robert A. Buhrman (Ithaca, New York); Oukjae Lee (Ithaca, New York); Daniel C. Ralph (Ithaca, New York) |
| ABSTRACT | Techniques, systems, and devices are disclosed for implementing a quasi-linear spin-torque nano-oscillator based on exertion of a spin-transfer torque on the local magnetic moments in the magnetic layer and precession of the magnetic moments in the magnetic layer within a spin valve. Examples of spin-torque nano-oscillators (STNOs) are disclosed to use spin polarized currents to excite nano magnets that undergo persistent oscillations at RF or microwave frequencies. The spin currents are applied in a non-uniform manner to both excite the nano magnets into oscillations and generate dynamic damping at large amplitude as a feedback to reduce the nonlinearity associated with mixing amplitude and phase fluctuations. |
| FILED | Tuesday, January 14, 2014 |
| APPL NO | 14/760999 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 15/006 (20130101) Automatic Control, Starting, Synchronisation, or Stabilisation of Generators of Electronic Oscillations or Pulses H03L 7/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577822 | Pedersen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Altera Corporation (San Jose, California) |
| ASSIGNEE(S) | Altera Corporation (San Jose, California) |
| INVENTOR(S) | Bruce B. Pedersen (Sunnyvale, California) |
| ABSTRACT | Methods and systems are provided for securely authenticating data of an integrated circuit. By authenticating data having keystream blocks inserted between ciphertext portions, it becomes more difficult to mount successful authentication-based attacks. |
| FILED | Wednesday, October 02, 2013 |
| APPL NO | 14/044574 |
| ART UNIT | 2433 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/30 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/18 (20130101) H04L 9/32 (20130101) H04L 9/0631 (20130101) Original (OR) Class H04L 9/3242 (20130101) H04L 63/00 (20130101) H04L 65/60 (20130101) H04L 2209/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577875 | Agrawal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dakshi Agrawal (Monsey, New York); Chatschik Bisdikian (Chappaqua, New York); Kang-Won Lee (Nanuet, New York); Ramya Raghavendra (White Plains, New York); Ho Yin Starsky Wong (Ossining, New York) |
| ABSTRACT | An aspect of this invention is a computer-executable method for distributing one or more features associated with information to be transported by a communications network that includes a plurality of end nodes interconnected via a plurality of network nodes. The method includes receiving one or more features associated with information to be transported by the communications network, wherein the one or more features are specified at an end node of the plurality of end nodes for receipt by a network node of the plurality of network nodes; responsive to the one or more received features, configuring at least a portion of the communications network to perform actions on information based upon the features; receiving the information using the plurality of network nodes; and based at least on the received features and the configuring, performing one or more actions with the information. Illustratively, the one or more actions comprise sending the information to one or more edge entity nodes in accordance with the configuring and the received features. |
| FILED | Monday, October 15, 2012 |
| APPL NO | 13/651951 |
| ART UNIT | 2463 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 41/082 (20130101) H04L 41/0803 (20130101) Original (OR) Class H04L 41/5054 (20130101) H04L 45/04 (20130101) H04L 47/23 (20130101) H04L 47/24 (20130101) H04L 47/32 (20130101) H04L 47/2441 (20130101) Wireless Communication Networks H04W 28/0268 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09578024 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI INTERNATIONAL (Menlo Park, California) |
| INVENTOR(S) | Hui Cheng (Bridgewater, New Jersey); Omar Javed (Franklin Park, New Jersey); JieJie Zhu (East Windsor, New Jersey) |
| ABSTRACT | Technology for performing continuous authentication of a mobile device utilizes user activity context data and biometric signature data related to the user. A biometric signature can be selected based on the activity context, and the selected biometric signature can be used to verify the identity of the user. |
| FILED | Friday, August 21, 2015 |
| APPL NO | 14/832524 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/32 (20130101) G06F 21/316 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/12 (20130101) H04L 63/0861 (20130101) Original (OR) Class Wireless Communication Networks H04W 12/06 (20130101) H04W 12/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09578051 | Hitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | 21CT, Inc. (Austin, Texas) |
| ASSIGNEE(S) | 21CT, Inc. (Austin, Texas) |
| INVENTOR(S) | Laura Hitt (Austin, Texas); Matt McClain (Austin, Texas) |
| ABSTRACT | A method for identifying a threatening network comprises an asymmetric threat signature (AT-SIG) algorithm comprising a network movement before/after algorithm that provides a graphical plot of changes in network transaction activity from before to after a specified time and further comprising one or more of: a network progression algorithm that provides a graphical plot to analyze behavior in small increments of time without specification or emphasis upon a particular time or event; a statistical network anomaly ranking algorithm that provides as output a ranked list of the networks; and an anomaly trend graphs algorithm that analyzes and visualizes the networks' anomaly scores over time. Also disclosed are an AT-SIG system and a software program product. |
| FILED | Friday, February 05, 2016 |
| APPL NO | 15/017039 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1425 (20130101) H04L 63/1433 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 09573094 | Kelly |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sean M. Kelly (Pittsford, New York) |
| ASSIGNEE(S) | PRAXAIR TECHNOLOGY, INC. (Danbury, Connecticut) |
| INVENTOR(S) | Sean M. Kelly (Pittsford, New York) |
| ABSTRACT | A system and method for temperature control in an oxygen transport membrane based reactor is provided. The system and method involves introducing a specific quantity of cooling air or trim air in between stages in a multistage oxygen transport membrane based reactor or furnace to maintain generally consistent surface temperatures of the oxygen transport membrane elements and associated reactors. The associated reactors may include reforming reactors, boilers or process gas heaters. |
| FILED | Wednesday, October 08, 2014 |
| APPL NO | 14/509406 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Separation B01D 53/46 (20130101) Original (OR) Class B01D 53/226 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/009 (20130101) B01J 8/025 (20130101) B01J 8/062 (20130101) B01J 8/065 (20130101) B01J 19/2475 (20130101) B01J 2208/00176 (20130101) B01J 2208/00371 (20130101) B01J 2219/00006 (20130101) B01J 2219/24 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/382 (20130101) C01B 3/384 (20130101) C01B 3/386 (20130101) C01B 13/0251 (20130101) C01B 2203/148 (20130101) C01B 2203/0233 (20130101) C01B 2203/0261 (20130101) C01B 2203/0805 (20130101) C01B 2203/0844 (20130101) C01B 2203/1241 (20130101) Acyclic or Carbocyclic Compounds C07C 1/041 (20130101) C07C 1/0485 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573249 | Kuntz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Joshua D. Kuntz (Livermore, California); German F. Ellsworth (Livermore, California); Fritz J. Swenson (Tracy, California); Patrick G. Allen (Pleasanton, California) |
| ABSTRACT | According to one embodiment, a composite product includes: a matrix material including hexagonal boron nitride and one or more borate binders; and a plurality of cubic boron nitride particles dispersed in the matrix material. According to another embodiment, a composite product includes: a matrix material including hexagonal boron nitride and amorphous boron nitride; and a plurality of cubic boron nitride particles dispersed in the matrix material. |
| FILED | Thursday, November 19, 2015 |
| APPL NO | 14/946606 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Tools for Grinding, Buffing, or Sharpening B24D 3/00 (20130101) B24D 3/04 (20130101) Original (OR) Class B24D 18/0009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574197 | Withers, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Sydnor T. Withers, III (Madison, Wisconsin); Miguel A. Dominguez (Madison, Wisconsin); Matthew P. DeLisa (Ithaca, New York); Charles H. Haitjema (Ithaca, New York) |
| ABSTRACT | Disclosed herein are systems and methods for producing recombinant proteins utilizing mutant E. coli strains containing expression vectors carrying nucleic acids encoding the proteins, and secretory signal sequences to direct the secretion of the proteins to the culture medium. Host cells transformed with the expression vectors are also provided. |
| FILED | Friday, July 15, 2016 |
| APPL NO | 15/211632 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/245 (20130101) C07K 2319/034 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574274 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Carolina (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Fanglin Chen (Irmo, South Carolina); Yao Wang (Columbia, South Carolina) |
| ABSTRACT | Methods for simultaneous syngas generation by opposite sides of a solid oxide co-electrolysis cell are provided. The method can comprise exposing a cathode side of the solid oxide co-electrolysis cell to a cathode-side feed stream; supplying electricity to the solid oxide co-electrolysis cell such that the cathode side produces a product stream comprising hydrogen gas and carbon monoxide gas while supplying oxygen ions to an anode side of the solid oxide co-electrolysis cell; and exposing the anode side of the solid oxide co-electrolysis cell to an anode-side feed stream. The cathode-side feed stream comprises water and carbon dioxide, and the anode-side feed stream comprises methane gas such that the methane gas reacts with the oxygen ions to produce hydrogen and carbon monoxide. The cathode-side feed stream can further comprise nitrogen, hydrogen, or a mixture thereof. |
| FILED | Monday, April 20, 2015 |
| APPL NO | 14/690687 |
| ART UNIT | 1756 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 1/02 (20130101) Original (OR) Class C25B 9/08 (20130101) C25B 9/10 (20130101) C25B 11/04 (20130101) C25B 13/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574431 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Jy-An John Wang (Oak Ridge, Tennessee); Hong Wang (Oak Ridge, Tennessee); Fei Ren (Philadelphia, Pennsylvania); Thomas S. Cox (Oak Ridge, Tennessee) |
| ABSTRACT | A rotary shutter valve 500 is used for geothermal reservoir stimulation. The valve 500 includes a pressure chamber 520 for holding a working fluid (F) under pressure. A rotatable shutter 532 is turned with a powering device 544 to periodically align one or more windows 534 with one or more apertures 526 in a bulkhead 524. When aligned, the pressurized working fluid (F) flows through the bulkhead 524 and enters a pulse cavity 522, where it is discharged from the pulse cavity 522 as pressure waves 200. The pressure wave propagation 200 and eventual collapse of the bubbles 202 can be transmitted to a target rock surface 204 either in the form of a shock wave 206, or by micro jets 208, depending on the bubble-surface distance. Once cavitation at the rock face begins, fractures are initiated in the rock to create a network of micro-fissures for enhanced heat transfer. |
| FILED | Tuesday, March 25, 2014 |
| APPL NO | 14/224367 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 28/00 (20130101) E21B 43/26 (20130101) Original (OR) Class Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 7/04 (20130101) Producing or Use of Heat Not Otherwise Provided For F24J 3/085 (20130101) F24J 2003/088 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574533 | Monaghan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | James Christopher Monaghan (Moore, South Carolina); Thomas Edward Johnson (Greer, South Carolina); Heath Michael Ostebee (Easley, South Carolina) |
| ABSTRACT | A fuel injection head for use in a fuel injection nozzle comprises a monolithic body portion comprising an upstream face, an opposite downstream face, and a peripheral wall extending therebetween. A plurality of pre-mix tubes are integrally formed with and extend axially through the body portion. Each of the pre-mix tubes comprises an inlet adjacent the upstream face, an outlet adjacent the downstream face, and a channel extending between the inlet and the outlet. Each pre-mix tube also includes at least one fuel injector that at least partially extends outward from an exterior surface of the pre-mix tube, wherein the fuel injector is integrally formed with the pre-mix tube and is configured to facilitate fuel flow between the body portion and the channel. |
| FILED | Thursday, June 13, 2013 |
| APPL NO | 13/916767 |
| ART UNIT | 3752 — Fluid Handling and Dispensing |
| CURRENT CPC | Spraying Apparatus; Atomising Apparatus; Nozzles B05B 7/04 (20130101) B05B 7/08 (20130101) Supplying Combustion Engines in General With Combustible Mixtures or Constituents Thereof F02M 55/008 (20130101) Original (OR) Class F02M 2200/80 (20130101) Generating Combustion Products of High Pressure or High Velocity, e.g Gas-turbine Combustion Chambers F23R 3/10 (20130101) F23R 3/28 (20130101) F23R 3/286 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/494 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574713 | Turner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Terry D. Turner (Idaho Falls, Idaho); Bruce M. Wilding (Idaho Falls, Idaho); Michael G. McKellar (Idaho Falls, Idaho); Lee P. Shunn (Idaho Falls, Idaho) |
| ASSIGNEE(S) | BATTELLE ENERGY ALLIANCE, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Terry D. Turner (Idaho Falls, Idaho); Bruce M. Wilding (Idaho Falls, Idaho); Michael G. McKellar (Idaho Falls, Idaho); Lee P. Shunn (Idaho Falls, Idaho) |
| ABSTRACT | A vaporization chamber may include at least one conduit and a shell. The at least one conduit may have an inlet at a first end, an outlet at a second end and a flow path therebetween. The shell may surround a portion of each conduit and define a chamber surrounding the portion of each conduit. Additionally, a plurality of discrete apertures may be positioned at longitudinal intervals in a wall of each conduit, each discrete aperture of the plurality of discrete apertures sized and configured to direct a jet of fluid into each conduit from the chamber. A liquid may be vaporized by directing a first fluid comprising a liquid into the inlet at the first end of each conduit, directing jets of a second fluid into each conduit from the chamber through discrete apertures in a wall of each conduit and transferring heat from the second fluid to the first fluid. |
| FILED | Wednesday, November 03, 2010 |
| APPL NO | 12/938761 |
| ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Pipe-line Systems; Pipe-lines F17D 1/18 (20130101) Original (OR) Class Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/00 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0391 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574801 | Seletskiy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Denis V. Seletskiy (Albuquerque, New Mexico); Richard Epstein (Santa Fe, New Mexico); Markus P. Hehlen (Los Alamos, New Mexico); Mansoor Sheik-Bahae (Albuquerque, New Mexico) |
| ASSIGNEE(S) | STC.UNM (Albuquerque, New Mexico) |
| INVENTOR(S) | Denis V. Seletskiy (Albuquerque, New Mexico); Richard Epstein (Santa Fe, New Mexico); Markus P. Hehlen (Los Alamos, New Mexico); Mansoor Sheik-Bahae (Albuquerque, New Mexico) |
| ABSTRACT | A method and device for cooling electronics is disclosed. The device includes a doped crystal configured to resonate at a Stark manifold resonance capable of cooling the crystal to a temperature of from about 110K to about 170K. The crystal host resonates in response to input from an excitation laser tuned to exploit the Stark manifold resonance corresponding to the cooling of the crystal. |
| FILED | Thursday, December 23, 2010 |
| APPL NO | 12/977465 |
| ART UNIT | 3744 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 21/00 (20130101) Original (OR) Class F25B 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574903 | Vilim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Richard B. Vilim (Sugar Grove, Illinois); Alexander Heifetz (Buffalo Grove, Illinois) |
| ABSTRACT | A method and system for performing transient multivariable sensor evaluation. The method and system includes a computer system for identifying a model form, providing training measurement data, generating a basis vector, monitoring system data from sensor, loading the system data in a non-transient memory, performing an estimation to provide desired data and comparing the system data to the desired data and outputting an alarm for a defective sensor. |
| FILED | Thursday, December 19, 2013 |
| APPL NO | 14/134790 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Not Specially Adapted for a Specific Variable; Arrangements for Measuring Two or More Variables Not Covered in a Single Other Subclass; Tariff Metering Apparatus; Measuring or Testing Not Otherwise Provided for G01D 3/08 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00563 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575042 | Okrut et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alexander Okrut (Berkeley, California); Xiaoying Ouyang (El Cerrito, California); Ron Runnebaum (Berkeley, California); Bruce C. Gates (El Macero, California); Alexander Katz (Richmond, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alexander Okrut (Berkeley, California); Xiaoying Ouyang (El Cerrito, California); Ron Runnebaum (Berkeley, California); Bruce C. Gates (El Macero, California); Alexander Katz (Richmond, California) |
| ABSTRACT | Provided is an organic ligand-bound metal surface that selects one gaseous species over another. The species can be closely sized molecular species having less than 1 Angstrom difference in kinetic diameter. In one embodiment, the species comprise carbon monoxide and ethylene. Such organic ligand-bound metal surfaces can be successfully used in gas phase separations or purifications, sensing, and in catalysis. |
| FILED | Friday, May 30, 2014 |
| APPL NO | 14/292252 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Separation B01D 53/00 (20130101) B01D 53/02 (20130101) B01D 2253/20 (20130101) B01D 2257/502 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/223 (20130101) B01J 20/3483 (20130101) B01J 31/2295 (20130101) Acyclic or Carbocyclic Compounds C07C 7/12 (20130101) C07C 7/12 (20130101) C07C 11/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/004 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/52 (20151101) Technical Subjects Covered by Former US Classification Y10T 436/205831 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575177 | Schroeder et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | Texas Tech University System (Lubbock, Texas) |
| INVENTOR(S) | John Schroeder (Lubbock, Texas); Brian Hirth (Lubbock, Texas); Jerry Guynes (Lubbock, Texas) |
| ABSTRACT | The present invention provides an apparatus and method for obtaining data to determine one or more characteristics of a wind flow field using one or more radars. Data is collected from the one or more radars, and analyzed to determine the one or more characteristics of the wind flow field. The one or more radars are positioned to have a portion of the wind flow field within a scanning sector of the one or more radars. |
| FILED | Saturday, July 27, 2013 |
| APPL NO | 13/952611 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Wind Motors F03D 17/00 (20160501) Indexing Scheme Relating to Wind, Spring, Weight, Inertia or Like Motors, to Machines or Engines for Liquids Covered by Subclasses F03B, F03D and F03G F05B 2270/32 (20130101) F05B 2270/321 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/001 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/87 (20130101) G01S 13/95 (20130101) Original (OR) Class G01S 13/589 (20130101) G01S 13/951 (20130101) G01S 13/956 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09576127 | Stolfo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Salvatore J. Stolfo (Ridgewood, New Jersey); Wei-Jen Li (Rego Park, New York); Angelos D. Keromytis (New York, New York); Elli Androulaki (New York, New York) |
| ABSTRACT | Methods, media, and systems for detecting attack are provided. In some embodiments, the methods include: comparing at least part of a document to a static detection model; determining whether attacking code is included in the document based on the comparison of the document to the static detection model; executing at least part of the document; determining whether attacking code is included in the document based on the execution of the at least part of the document; and if attacking code is determined to be included in the document based on at least one of the comparison of the document to the static detection model and the execution of the at least part of the document, reporting the presence of an attack. In some embodiments, the methods include: selecting a data segment in at least one portion of an electronic document; determining whether the arbitrarily selected data segment can be altered without causing the electronic document to result in an error when processed by a corresponding program; in response to determining that the arbitrarily selected data segment can be altered, arbitrarily altering the data segment in the at least one portion of the electronic document to produce an altered electronic document; and determining whether the corresponding program produces an error state when the altered electronic document is processed by the corresponding program. |
| FILED | Monday, July 21, 2014 |
| APPL NO | 14/336649 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/50 (20130101) Original (OR) Class G06F 21/56 (20130101) G06F 21/562 (20130101) G06F 21/566 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09576327 | Ghosh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Soumyadip Ghosh (PeekSkill, New York); Jonathan R. Hosking (Scarsdale, New York); Ramesh Natarajan (Pleasantville, New York); Shivaram Subramaniam (Danbury, Connecticut); Xiaoxuan Zhang (Park Ridge, New Jersey) |
| ABSTRACT | A predictive-control approach allows an electricity provider to monitor and proactively manage peak and off-peak residential intra-day electricity usage in an emerging smart energy grid using time-dependent dynamic pricing incentives. The daily load is modeled as time-shifted, but cost-differentiated and substitutable, copies of the continuously-consumed electricity resource, and a consumer-choice prediction model is constructed to forecast the corresponding intra-day shares of total daily load according to this model. This is embedded within an optimization framework for managing the daily electricity usage. A series of transformations are employed, including the reformulation-linearization technique (RLT) to obtain a Mixed-Integer Programming (MIP) model representation of the resulting nonlinear optimization problem. In addition, various regulatory and pricing constraints are incorporated in conjunction with the specified profit and capacity utilization objectives. |
| FILED | Thursday, June 06, 2013 |
| APPL NO | 13/912181 |
| ART UNIT | 2121 — AI & Simulation/Modeling |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0206 (20130101) G06Q 50/06 (20130101) Original (OR) Class Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 2003/003 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/54 (20130101) Y04S 20/222 (20130101) Y04S 50/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09576694 | Gogotsi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yury Gogotsi (Warminster, Pennsylvania); Vadym Mochalin (Philadelphia, Pennsylvania); John Kenneth McDonough, IV (Collegeville, Pennsylvania); Patrice Simon (Toulouse, France); Pierre-Louis Taberna (Escalquens, France) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania); Universite Paul Abatier De Toulouse France (, France) |
| INVENTOR(S) | Yury Gogotsi (Warminster, Pennsylvania); Vadym Mochalin (Philadelphia, Pennsylvania); John Kenneth McDonough, IV (Collegeville, Pennsylvania); Patrice Simon (Toulouse, France); Pierre-Louis Taberna (Escalquens, France) |
| ABSTRACT | This invention relates to novel applications for alliform carbon, useful in conductors and energy storage devices, including electrical double layer capacitor devices and articles incorporating such conductors and devices. Said alliform carbon particles are in the range of 2 to about 20 percent by weight, relative to the weight of the entire electrode. Said novel applications include supercapacitors and associated electrode devices, batteries, bandages and wound healing, and thin-film devices, including display devices. |
| FILED | Friday, September 16, 2011 |
| APPL NO | 13/823336 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/24 (20130101) Crimping or Curling Fibres, Filaments, Threads, or Yarns; Yarns or Threads D02G 3/36 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Original (OR) Class Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 11/36 (20130101) H01G 11/58 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/96 (20130101) H01M 4/583 (20130101) H01M 4/625 (20130101) H01M 4/663 (20130101) H01M 4/667 (20130101) H01M 4/668 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/50 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/265 (20150115) Y10T 428/292 (20150115) Y10T 442/603 (20150401) Y10T 442/3057 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577250 | Xiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Jie Xiao (Richland, Washington); Dongping Lu (Richland, Washington); Jun Liu (Richland, Washington); Jiguang Zhang (Richland, Washington); Gordon L. Graff (West Richland, Washington) |
| ABSTRACT | Electrodes having nanostructure and/or utilizing nanoparticles of active materials and having high mass loadings of the active materials can be made to be physically robust and free of cracks and pinholes. The electrodes include nanoparticles having electroactive material, which nanoparticles are aggregated with carbon into larger secondary particles. The secondary particles can be bound with a binder to form the electrode. |
| FILED | Tuesday, February 11, 2014 |
| APPL NO | 14/177954 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/139 (20130101) H01M 4/362 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/0404 (20130101) H01M 4/0471 (20130101) H01M 4/485 (20130101) H01M 4/581 (20130101) H01M 4/587 (20130101) H01M 4/621 (20130101) H01M 4/625 (20130101) H01M 4/1393 (20130101) H01M 4/1395 (20130101) H01M 4/1397 (20130101) H01M 4/5815 (20130101) H01M 4/5825 (20130101) H01M 2004/021 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
09577298 — High efficiency iron electrode and additives for use in rechargeable iron-based batteries
| US 09577298 | Narayan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sri R. Narayan (Arcadia, California); G. K. Surya Prakash (Hacienda Heights, California); Robert Aniszfeld (Los Angeles, California); Aswin Manohar (Los Angeles, California); Souradip Malkhandi (Los Angeles, California); Bo Yang (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Sri R. Narayan (Arcadia, California); G. K. Surya Prakash (Hacienda Heights, California); Robert Aniszfeld (Los Angeles, California); Aswin Manohar (Los Angeles, California); Souradip Malkhandi (Los Angeles, California); Bo Yang (Los Angeles, California) |
| ABSTRACT | An iron electrode and a method of manufacturing an iron electrode for use in an iron-based rechargeable battery are disclosed. In one embodiment, the iron electrode includes carbonyl iron powder and one of a metal sulfide additive or metal oxide additive selected from the group of metals consisting of bismuth, lead, mercury, indium, gallium, and tin for suppressing hydrogen evolution at the iron electrode during charging of the iron-based rechargeable battery. An iron-air rechargeable battery including an iron electrode comprising carbonyl iron is also disclosed, as is an iron-air battery wherein at least one of the iron electrode and the electrolyte includes an organosulfur additive. |
| FILED | Friday, June 15, 2012 |
| APPL NO | 13/524761 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/12 (20130101) H01M 4/62 (20130101) H01M 4/364 (20130101) H01M 4/622 (20130101) H01M 12/08 (20130101) Original (OR) Class H01M 12/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 09572506 | Schmidt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Robert N. Schmidt (Cleveland, Ohio); Frederick J. Lisy (Euclid, Ohio); Gerard G. Skebe (Eastlake, Ohio); Troy S. Prince (Cleveland Heights, Ohio) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Robert N. Schmidt (Cleveland, Ohio); Frederick J. Lisy (Euclid, Ohio); Gerard G. Skebe (Eastlake, Ohio); Troy S. Prince (Cleveland Heights, Ohio) |
| ABSTRACT | The present invention relates to a physiological recording electrode, a method, and apparatus for attaching the physiological electrode to a subject. The physiological electrode comprises a substrate having an upper and a lower surface, and at least one penetrator(s) protruding from the upper surface of the substrate. The penetrator(s) is capable of piercing through the stratum corneum or outer layer of the skin, and transmitting an electric potential from the lower layers of the epidermis through the penetrator(s) which can be measured, or detecting agents from the lower layers of the epidermis primarily the stratum germinativum layer. At least one epidermis stop may be provided resulting in the formation of detritus troughs interposed between adjacent penetrator(s) and epidermis stops. The physiological electrode is attached to a subject by means of the apparatus and method for attaching same. The present invention also includes a method of sensing biopotentials in the skin. |
| FILED | Wednesday, December 15, 2010 |
| APPL NO | 12/968496 |
| ART UNIT | 3739 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0408 (20130101) Original (OR) Class A61B 5/0478 (20130101) A61B 5/0492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09572834 | Tour et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | James M. Tour (Bellaire, Texas); Jacob Berlin (Monrovia, California); Daniela Marcano (Houston, Texas); Ashley Leonard (Houston, Texas); Thomas A. Kent (Houston, Texas); Robia G. Pautler (Pearland, Texas); Brittany Bitner (Dallas Center, Iowa); Taeko Inoue (Pasadena, Texas) |
| ASSIGNEE(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas); BAYLOR COLLEGE OF MEDICINE (Houston, Texas) |
| INVENTOR(S) | James M. Tour (Bellaire, Texas); Jacob Berlin (Monrovia, California); Daniela Marcano (Houston, Texas); Ashley Leonard (Houston, Texas); Thomas A. Kent (Houston, Texas); Robia G. Pautler (Pearland, Texas); Brittany Bitner (Dallas Center, Iowa); Taeko Inoue (Pasadena, Texas) |
| ABSTRACT | In some embodiments, the present invention provides methods of treating oxidative stress in a subject by administering a therapeutic composition to the subject. In some embodiments, the therapeutic composition comprises a carbon nanomaterial with anti-oxidant activity. In some embodiments, the anti-oxidant activity of the carbon nanomaterial corresponds to ORAC values between about 200 to about 15,000. In some embodiments, the administered carbon nanomaterials include at least one of single-walled nanotubes, double-walled nanotubes, triple-walled nanotubes, multi-walled nanotubes, ultra-short nanotubes, graphene, graphene nanoribbons, graphite, graphite oxide nanoribbons, carbon black, oxidized carbon black, hydrophilic carbon clusters, and combinations thereof. In some embodiments, the carbon nanomaterial is an ultra-short single-walled nanotube that is functionalized with a plurality of solubilizing groups. In some embodiments, the carbon nanomaterial is a polyethylene glycol functionalized hydrophilic carbon cluster (PEG-HCC). In some embodiments, the administered therapeutic compositions of the present invention may also include an active agent or targeting agent associated with the carbon nanomaterial. Additional embodiments of the present invention pertain to the aforementioned carbon nanomaterial compositions for treating oxidative stress. |
| FILED | Thursday, April 26, 2012 |
| APPL NO | 14/114007 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/713 (20130101) A61K 31/713 (20130101) A61K 33/44 (20130101) Original (OR) Class A61K 33/44 (20130101) A61K 45/06 (20130101) A61K 47/48215 (20130101) A61K 47/48869 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573871 | Vidhani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida); Robert A. Holton (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Dinesh V. Vidhani (Tallahassee, Florida); Marie E. Krafft (Tallahassee, Florida); Igor Alabugin (Tallahassee, Florida) |
| ABSTRACT | A novel Rh(I)-catalyzed approach to synthesizing functionalized (E,Z) dienal compounds has been developed via tandem transformation where a stereoselective hydrogen transfer follows a propargyl Claisen rearrangement. Z-Stereochemistry of the first double bond suggests the involvement of a six-membered cyclic intermediate whereas the E-stereochemistry of the second double bond stems from the subsequent protodemetallation step giving an (E,Z)-dienal. The reaction may be represented by the following sequence. |
| FILED | Thursday, May 28, 2015 |
| APPL NO | 14/724016 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 41/08 (20130101) C07C 41/08 (20130101) C07C 41/08 (20130101) C07C 41/08 (20130101) C07C 43/16 (20130101) C07C 43/162 (20130101) C07C 43/164 (20130101) C07C 45/513 (20130101) Original (OR) Class C07C 45/513 (20130101) C07C 45/513 (20130101) C07C 45/513 (20130101) C07C 47/21 (20130101) C07C 47/225 (20130101) C07C 47/232 (20130101) C07C 253/30 (20130101) C07C 253/30 (20130101) C07C 253/30 (20130101) C07C 255/54 (20130101) C07C 255/56 (20130101) Heterocyclic Compounds C07D 307/42 (20130101) C07D 307/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09573908 | Bassler et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bonnie L. Bassler (Princeton, New Jersey); Wai-Leung Ng (Lawrenceville, New Jersey); Lark J. Perez (Ewing, New Jersey); Jianping Cong (Plainsboro, New Jersey); Martin F. Semmelhack (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Bonnie L. Bassler (Princeton, New Jersey); Wai-Leung Ng (Lawrenceville, New Jersey); Lark J. Perez (Ewing, New Jersey); Jianping Cong (Plainsboro, New Jersey); Martin F. Semmelhack (Princeton, New Jersey) |
| ABSTRACT | Using a whole-cell high-throughput screen, eleven molecules were identified that activate V. cholerae quorum sensing (QS). Eight molecules are receptor agonists and three molecules are antagonists of LuxO, the central NtrC-type response regulator that controls the global V. cholerae QS cascade. Pro-QS molecules are used for the development of novel anti-infectives. |
| FILED | Wednesday, February 20, 2013 |
| APPL NO | 14/381432 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 43/707 (20130101) A01N 55/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) Heterocyclic Compounds C07D 253/075 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 7/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574134 | Wood et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanessa Wood (Cambridge, Massachusetts); Matthew J. Panzer (Cambridge, Massachusetts); Jonathan E. Halpert (McClean, Virginia); Moungi G. Bawendi (Cambridge, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Vanessa Wood (Cambridge, Massachusetts); Matthew J. Panzer (Cambridge, Massachusetts); Jonathan E. Halpert (McClean, Virginia); Moungi G. Bawendi (Cambridge, Massachusetts); Vladimir Bulovic (Lexington, Massachusetts) |
| ABSTRACT | A voltage driven light emitting device includes an electroluminescent material and semiconductor nanocrystals, luminescent organic small molecules, mixtures of emissive species molecules, or conductive polymers. The semiconductor nanocrystals, luminescent organic small molecules, mixtures of emissive species molecules, or conductive polymers emit light. The semiconductor nanocrystals, luminescent organic small molecules, mixtures of emissive species molecules, or conductive polymers can be doped to provide desired emission characteristics. Devices that share a substrate and emit more than one color may be conveniently made. |
| FILED | Friday, May 07, 2010 |
| APPL NO | 12/776126 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/565 (20130101) Original (OR) Class Electric Heating; Electric Lighting Not Otherwise Provided for H05B 33/14 (20130101) H05B 33/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574966 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Haiying Huang (Arlington, Texas); Jung-Chih Chiao (Grand Prairie, Texas); Ronald L. Carter (Arlington, Texas); Uday Shankar Tata (Arlington, Texas) |
| ABSTRACT | An apparatus and method is provided for monitoring a condition of a structure using a passive wireless antenna sensor having a known resonant frequency when mounted on the structure. A signal is transmitted with sweeping frequencies around a known resonant frequency to the passive wireless antenna sensor. A signal is received from the passive wireless antenna sensor and a resonant frequency of the passive wireless antenna sensor is determined based on the received signal. The determined resonant frequency is then compared to the known resonant frequency, whereby a change in the resonant frequency indicates a change in the condition of the structure. |
| FILED | Thursday, October 02, 2014 |
| APPL NO | 14/504933 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 5/0033 (20130101) G01M 5/0083 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575021 | Blick et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Robert H. Blick (Madison, Wisconsin); Minrui Yu (Madison, Wisconsin) |
| ABSTRACT | A method of forming extremely small pores in a substrate may be used to produce, for example, an apparatus for the study of biological molecules, by providing a small pore in a piezoelectric substrate having electrodes, the latter that may be energized to change the pore dimensions. |
| FILED | Tuesday, May 14, 2013 |
| APPL NO | 13/893761 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/006 (20130101) B23K 26/18 (20130101) B23K 26/40 (20130101) B23K 26/066 (20151001) B23K 26/382 (20151001) B23K 2203/50 (20151001) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/00 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/24273 (20150115) Y10T 428/24281 (20150115) Y10T 428/24612 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575138 | Salmani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Mohamadamin Salmani (Tallahassee, Florida); Chris S. Edrington (Tallahassee, Florida) |
| ABSTRACT | A novel method for real-time small-signal stability analysis for power electronic-based components in a power system. The method may be used to monitor a power system in real-time by perturbing the source side of an electronic-based component of the power system by injecting a current of about 0.5 to 1 percent of a nominal current of the power system at the source side and perturbing the load side of the power electronic-based component by injecting a voltage of about 0.5 to about 1 percent of a nominal voltage of the power system at the load side and varying the voltage at the load side. Time-domain results of the perturbations may be transferred to frequency-domain results and the stability of the power system may be monitored by obtaining a Nyquist contour and employing Generalized Nyquist Criterion or unit circle criterion. |
| FILED | Monday, April 18, 2016 |
| APPL NO | 15/131647 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 27/16 (20130101) G01R 31/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575139 | Salmani et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| INVENTOR(S) | Mohamadamin Salmani (Tallahassee, Florida); Chris S. Edrington (Tallahassee, Florida) |
| ABSTRACT | A novel method for real-time small-signal stability analysis for power electronic-based components in a power system. The method may be used to monitor a power system in real-time by perturbing the source side of an electronic-based component of the power system by injecting a current of about 0.5 to 1 percent of a nominal current of the power system at the source side, while simultaneously perturbing the load side of the power electronic-based component by varying the voltage at the load side. Time-domain results of the simultaneous perturbations may be transferred to frequency-domain results and the stability of the power system may be monitored by obtaining a Nyquist contour and employing Generalized Nyquist Criterion or unit circle criterion. |
| FILED | Monday, April 18, 2016 |
| APPL NO | 15/131653 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/2506 (20130101) G01R 27/02 (20130101) G01R 31/40 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577731 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | National Science Foundation (Arlington, Virginia) |
| INVENTOR(S) | Xinyu Zhang (Madison, Wisconsin); Sanjib Sur (Madison, Wisconsin); Teng Wei (Madison, Wisconsin) |
| ABSTRACT | The inventors have recognized that in RF communication systems, by switching between transmit antennas of an RF transmitter on a sub-symbol basis (antenna index coding), and/or by adaptively determining how often antenna switching occurs (adaptive antenna hopping), an increased amount of data may be wirelessly transmitted to an RF receiver without significantly increasing energy consumption. The inventors have determined that in certain systems, such as ZigBee, data symbols consist of elementary waveform patterns, and that such waveform patterns for transmit antennas may be stored by an RF receiver for later determining transmit antennas for data symbols. The inventors have also determined that the invention may be applied in the frequency domain, such as to OFDM, by storing subcarrier waveform patterns for particular transmit antennas and later determining transmit antennas for subcarriers of data symbols. |
| FILED | Friday, October 23, 2015 |
| APPL NO | 14/921346 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 7/0413 (20130101) H04B 7/0604 (20130101) Original (OR) Class H04B 7/0825 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0033 (20130101) H04L 5/0023 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 09573324 | Nemir et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | David Charles Nemir (El Paso, Texas); Edward S. Rubio (Santa Teresa, New Mexico); Jan Bastian Beck (El Paso, Texas) |
| ASSIGNEE(S) | TXL GROUP, INC. (El Paso, Texas) |
| INVENTOR(S) | David Charles Nemir (El Paso, Texas); Edward S. Rubio (Santa Teresa, New Mexico); Jan Bastian Beck (El Paso, Texas) |
| ABSTRACT | Systems and methods for producing a dense, well bonded solid material from a powder may include consolidating the powder utilizing any suitable consolidation method, such as explosive shockwave consolidation. The systems and methods may also include a post-processing thermal treatment that exploits a mismatch between the coefficients of thermal expansion between the consolidated material and the container. Due to the mismatch in the coefficients, internal pressure on the consolidated material during the heat treatment may be increased. |
| FILED | Wednesday, June 03, 2015 |
| APPL NO | 14/729439 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 3/08 (20130101) Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/02 (20130101) B22F 3/03 (20130101) B22F 3/08 (20130101) B22F 2003/248 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 43/52 (20130101) B29C 67/04 (20130101) Original (OR) Class Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574080 | Street et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kenneth Street (North Olmsted, Ohio); Oleg A Voronov (East Strandsburg, Pennsylvania); Bernard H Kear (Whitehouse Station, New Jersey) |
| ASSIGNEE(S) | The United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Kenneth Street (North Olmsted, Ohio); Oleg A Voronov (East Strandsburg, Pennsylvania); Bernard H Kear (Whitehouse Station, New Jersey) |
| ABSTRACT | Systems, methods, and articles of manufacture related to composite materials are discussed herein. These materials can be based on a mixture of diamond particles with a matrix and fibers or fabrics. The matrix can be formed into the composite material through optional pressurization and via heat treatment. These materials display exceptionally low friction coefficient and superior wear resistance in extreme environments. |
| FILED | Tuesday, December 06, 2011 |
| APPL NO | 13/311987 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 27/38 (20130101) B32B 2255/02 (20130101) B32B 2260/021 (20130101) B32B 2307/746 (20130101) Non-metallic Elements; Compounds Thereof; C01B 31/06 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/00 (20130101) Compositions of Macromolecular Compounds C08L 63/00 (20130101) Original (OR) Class Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 29/04 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 427/103 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09576082 | Sparks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Lawrence C. Sparks (La Crescenta, California); Anthony J. Mannucci (Pasadena, California); Attila Komjathy (La Crescenta, California) |
| ABSTRACT | A method, system, apparatus, and computer program product provide the ability to analyze ionospheric slant total electron content (TEC) using global navigation satellite systems (GNSS)-based estimation. Slant TEC is estimated for a given set of raypath geometries by fitting historical GNSS data to a specified delay model. The accuracy of the specified delay model is estimated by computing delay estimate residuals and plotting a behavior of the delay estimate residuals. An ionospheric threat model is computed based on the specified delay model. Ionospheric grid delays (IGDs) and grid ionospheric vertical errors (GIVEs) are computed based on the ionospheric threat model. |
| FILED | Wednesday, July 10, 2013 |
| APPL NO | 13/939014 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/07 (20130101) G01S 19/20 (20130101) G01S 19/41 (20130101) Electric Digital Data Processing G06F 17/5009 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577177 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Ari D. Brown (Baltimore, Maryland); Vilem Mikula (Hyattsville, Maryland) |
| ABSTRACT | A method of fabricating circuitry in a wafer includes depositing a superconducting metal on a silicon on insulator wafer having a handle wafer, coating the wafer with a sacrificial layer and bonding the wafer to a thermally oxide silicon wafer with a first epoxy. The method includes flipping the wafer, thinning the flipped wafer by removing a handle wafer, etching a buried oxide layer, depositing a superconducting layer, bonding the wafer to a thermally oxidized silicon wafer having a handle wafer using an epoxy, flipping the wafer again, thinning the flipped wafer, etching a buried oxide layer from the wafer and etching the sacrificial layer from the wafer. The result is a wafer having superconductive circuitry on both sides of an ultra-thin silicon layer. |
| FILED | Wednesday, May 25, 2016 |
| APPL NO | 15/164365 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 09572338 | Koehler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Philip G. Koehler (Gainesville, Florida); Roberto M. Pereira (Gainesville, Florida); Enrico Paolo Levi (Jacksonville, Florida) |
| ABSTRACT | Dual action lethal containers, systems and methods and novel compositions and formulas which are used to kill mosquitoes and their larvae. Generally pyramid shaped containers can have combined interior larvacidal and adultacidal coatings above and below a side opening in the container. A removable inclined grate cap can also allow for mosquitoes to enter into the container. Inclined stacked walls inside the container form attractive surfaces for mosquitoes to breed. Water-holding containers, such as flower pots, water holding dishes used under plant pots, vases, bird baths, and fountains and storm water inlets, can be coated with novel larvicide and/or adulticide coatings. Small objects can be coated with larvicide or larvicide and adulticide combination, which can be dropped in water-holding containers which can leach out pesticide over time which prevents mosquitoes from breeding in the water-holding containers. |
| FILED | Friday, February 19, 2016 |
| APPL NO | 15/048604 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/02 (20130101) A01M 1/20 (20130101) Original (OR) Class A01M 1/106 (20130101) A01M 25/00 (20130101) Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/08 (20130101) A01N 31/14 (20130101) A01N 37/06 (20130101) A01N 43/22 (20130101) A01N 43/30 (20130101) A01N 43/38 (20130101) A01N 43/40 (20130101) A01N 47/18 (20130101) A01N 53/00 (20130101) A01N 57/16 (20130101) A01N 63/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09574203 | Dong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Niu Dong (San Pablo, California); Colleen M McMahan (Sausalito, California); Maureen C Whalen (El Cerrito, California); Katrina Cornish (Wooster, Ohio); Terry A Coffelt (Chandler, Arizona) |
| ABSTRACT | The present invention relates to transgenic guayule plants that produce increased amounts of rubber uses thereof. |
| FILED | Friday, November 08, 2013 |
| APPL NO | 14/075761 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 5/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8243 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 09577175 | Nam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (Gaithersburg, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Washington, District of Columbia) |
| INVENTOR(S) | Sae Woo Nam (Boulder, Colorado); Burm Baek (Lafayette, Colorado); Francesco Marsili (Pasadena, California); Varun Verma (Boulder, Colorado) |
| ABSTRACT | An apparatus includes a base layer; and a superconducting nanowire disposed on the base layer in a continuous meander pattern and including an amorphous metal-metalloid alloy such that the apparatus is configured to detect single photons, and the continuous meander pattern includes: a plurality of parallel line segments; and a plurality of curved segments, wherein adjacent parallel line segments are joined by a curved segment. A method for making an apparatus for detecting single photons includes forming a base layer; forming a superconducting layer on the base layer; patterning the superconducting layer; and forming a continuous meander pattern from the superconducting layer, the continuous meander pattern includes a plurality of parallel line segments; and a plurality of curved segments, wherein adjacent parallel line segments are joined by a curved segment; and forming a dielectric layer on the continuous meander pattern, the dielectric layer including a dielectric material that is substantially transparent to a predetermined photon wavelength, wherein the apparatus is configured to detect single photons. |
| FILED | Tuesday, April 28, 2015 |
| APPL NO | 14/698442 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/42 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 09576127 | Stolfo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Salvatore J. Stolfo (Ridgewood, New Jersey); Wei-Jen Li (Rego Park, New York); Angelos D. Keromytis (New York, New York); Elli Androulaki (New York, New York) |
| ABSTRACT | Methods, media, and systems for detecting attack are provided. In some embodiments, the methods include: comparing at least part of a document to a static detection model; determining whether attacking code is included in the document based on the comparison of the document to the static detection model; executing at least part of the document; determining whether attacking code is included in the document based on the execution of the at least part of the document; and if attacking code is determined to be included in the document based on at least one of the comparison of the document to the static detection model and the execution of the at least part of the document, reporting the presence of an attack. In some embodiments, the methods include: selecting a data segment in at least one portion of an electronic document; determining whether the arbitrarily selected data segment can be altered without causing the electronic document to result in an error when processed by a corresponding program; in response to determining that the arbitrarily selected data segment can be altered, arbitrarily altering the data segment in the at least one portion of the electronic document to produce an altered electronic document; and determining whether the corresponding program produces an error state when the altered electronic document is processed by the corresponding program. |
| FILED | Monday, July 21, 2014 |
| APPL NO | 14/336649 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/50 (20130101) Original (OR) Class G06F 21/56 (20130101) G06F 21/562 (20130101) G06F 21/566 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 09576031 | Aggarwal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Charu Aggarwal (Yorktowne Heights, New York); Yanjie Fu (Newark, New Jersey); Srinivasan Parthasarathy (Yonkers, New York); Deepak Turaga (Elmsford, New York) |
| ABSTRACT | An automated outlier detection system implements an unsupervised set of processes to determine feature subspaces from a dataset; determine candidate exploratory actions, where each candidate exploratory action is a specific combination of a feature subspace and a parameterized instance of an outlier detection algorithm; and identify a set of optimal exploratory actions to recommend for execution on the dataset from among the candidate exploratory actions. Outlier scores obtained as a result of execution of the set of optimal exploratory actions are processed to obtain one or more outlier views such that each outlier view represents a consistent characterization of outliers by each optimal exploratory action corresponding to that outlier view. |
| FILED | Monday, February 08, 2016 |
| APPL NO | 15/018016 |
| ART UNIT | 2155 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Electric Digital Data Processing G06F 17/3053 (20130101) Original (OR) Class G06F 17/30572 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 09573906 | Wagner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carl E. Wagner (Glendale, Arizona); Peter W. Jurutka (Scottsdale, Arizona); Pamela A. Marshall (Peoria, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents, A Body Corporate of the State of Arizona Acting for and on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Carl E. Wagner (Glendale, Arizona); Peter W. Jurutka (Scottsdale, Arizona); Pamela A. Marshall (Peoria, Arizona) |
| ABSTRACT | The invention provides compounds of formulae (I), (II), (III), and (IV): and salts thereof, as well as pharmaceutical compositions comprising such compounds. The compounds are useful for treating cancers and Alzheimer's disease. |
| FILED | Thursday, September 13, 2012 |
| APPL NO | 14/344867 |
| ART UNIT | 1621 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 57/50 (20130101) C07C 57/62 (20130101) C07C 59/54 (20130101) C07C 2102/10 (20130101) Heterocyclic Compounds C07D 213/55 (20130101) C07D 213/80 (20130101) C07D 239/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 09572862 | Mahata et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sushil K. Mahata (San Diego, California); Gautam K. Bandyopadhyay (San Diego, California) |
| ABSTRACT | The invention provides methods for treating obesity in a subject comprising administering an effective amount of catestatin (CST) or its equivalent to a subject afflicted with obesity so as to maintain an effective amount of circulating catestatin in the subject to promote lipolysis and oxidation of released fatty acids in both liver and adipose tissue, thereby, reducing adipose tissue weight and hence treating obesity in the afflicted subject. |
| FILED | Monday, April 01, 2013 |
| APPL NO | 14/389722 |
| ART UNIT | 1676 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/155 (20130101) A61K 38/17 (20130101) Original (OR) Class Peptides C07K 14/575 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09575052 | Grimberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Brian T. Grimberg (Cleveland, Ohio); Robert Deissler (Cleveland, Ohio); William Condit (Cleveland, Ohio); Robert Brown (Cleveland, Ohio); Jason Jones (Cleveland, Ohio); Richard Bihary (Cleveland, Ohio) |
| ABSTRACT | A diagnostic device is provided that comprises a light source for transmitting a light beam through a blood sample to a light detector, and a permanent magnet, wherein one of the permanent magnet and blood sample is automatically movable relative to the other between a “HIGH” magnetic state position and a “LOW” magnetic state position, such that a substantially high magnetic field is applied to the blood sample causing any hemozoin in the blood sample to tend toward perpendicular orientation to the substantially magnetic field and the suppression, or enhancement of light based on its polarization, and a zero-to-near-zero magnetic field is applied to the blood sample causing the randomization of any hemozoin in the blood sample and a baseline amount of light to pass through the blood sample in the “LOW” magnetic state position. |
| FILED | Monday, February 10, 2014 |
| APPL NO | 14/766523 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 21/21 (20130101) G01N 21/59 (20130101) G01N 33/49 (20130101) Original (OR) Class G01N 2201/0683 (20130101) G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 09577918 | Bataineh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cray Inc. (Seattle, Washington) |
| ASSIGNEE(S) | Cray Inc. (Seattle, Washington) |
| INVENTOR(S) | Abdulla Bataineh (Irbid, Jordan); Thomas Court (Verona, Wisconsin); Duncan Roweth (Bristol, United Kingdom) |
| ABSTRACT | A system and algorithm configured to generate diversity at the traffic source so that packets are uniformly distributed over all of the available paths, but to increase the likelihood of taking a minimal path with each hop the packet takes. This is achieved by configuring routing biases so as to prefer non-minimal paths at the injection point, but increasingly prefer minimal paths as the packet proceeds, referred to herein as Increasing Minimal Bias (IMB). |
| FILED | Monday, November 19, 2012 |
| APPL NO | 13/681058 |
| ART UNIT | 2478 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/20 (20130101) Original (OR) Class H04L 45/122 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 21, 2017.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2017/fedinvent-patents-20170221.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page