FedInvent™ Patents
Patent Details for Tuesday, December 29, 2020
This page was updated on Monday, March 27, 2023 at 06:15 AM GMT
Department of Health and Human Services (HHS)
| US 10874333 | Pandey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Connecticut Children's Medical Center (Hartford, Connecticut) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Connecticut Children's Medical Center (Hartford, Connecticut) |
| INVENTOR(S) | Rishikesh Pandey (Arlington, Massachusetts); Nicolas Spegazzini (Arlington, Massachusetts); Luis H. Galindo (Fitchburg, Massachusetts); Ramachandra Dasari (Shererville, Indiana); Tulio Alberto Valdez (Simsbury, Connecticut) |
| ABSTRACT | Systems and methods are presented for the diagnosis of middle ear pathological conditions based on spectral signatures. Preferred embodiments provide for detection of one or more analytes from the tympanic membrane. Devices use spectral measurements including spectral imaging to non-invasively identify middle ear pathological conditions including cholesteatoma and acute otitis media by providing real-time information of differentially expressed molecules. Devices and methods can also be used to non-invasively detect and quantify blood analytes from the tympanic membrane. |
| FILED | Thursday, September 15, 2016 |
| APPL NO | 15/267057 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/07 (20130101) A61B 1/00009 (20130101) A61B 1/32 (20130101) A61B 1/043 (20130101) A61B 1/00045 (20130101) A61B 1/227 (20130101) A61B 1/0638 (20130101) A61B 1/0684 (20130101) A61B 5/12 (20130101) Original (OR) Class A61B 5/0071 (20130101) A61B 5/0075 (20130101) A61B 5/0084 (20130101) A61B 5/1459 (20130101) A61B 5/6817 (20130101) A61B 5/7282 (20130101) A61B 5/14532 (20130101) A61B 5/14546 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/44 (20130101) G01J 3/0218 (20130101) G01J 3/4406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) G01N 21/6486 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874610 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Huiping Liu (Chicago, Illinois); Erika K. Ramos (Chicago, Illinois); Nurmaa K. Dashzeveg (Chicago, Illinois); Golam Kibria (Chicago, Illinois) |
| ABSTRACT | This invention is related to use of exosomes for biomarker analysis for early detecting and characterizing of disease progression of cancer. Further, the invention provides bioengineered exosomes for use in methods of targeting and treating cancer. |
| FILED | Thursday, October 19, 2017 |
| APPL NO | 15/788709 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 9/1277 (20130101) A61K 31/7105 (20130101) A61K 38/00 (20130101) Peptides C07K 14/70503 (20130101) C07K 14/70596 (20130101) C07K 2319/03 (20130101) C07K 2319/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) G01N 33/57484 (20130101) G01N 33/57488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874622 | Aslan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Burcu Aslan (Houston, Texas); Gabriel Lopez-Berestein (Bellaire, Texas); Anil K. Sood (Pearland, Texas) |
| ABSTRACT | Disclosed are nanoparticles for the delivery of a therapeutic agent or a diagnostic agent to a subject that include a chitosan and a polyphosphate, wherein the chitosan nanoparticles are coated with polylactic acid. Methods of delivering a therapeutic agent or a diagnostic agent to a subject for the treatment or prevention of a disease are also disclosed. For example, the treatment of ovarian cancer in a subject by inhibiting the expression of ZNF034 is disclosed. |
| FILED | Thursday, June 23, 2016 |
| APPL NO | 15/738180 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0024 (20130101) A61K 9/5031 (20130101) A61K 9/5146 (20130101) A61K 9/5153 (20130101) Original (OR) Class A61K 9/5161 (20130101) A61K 31/713 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874631 | Mooberry et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Susan L Mooberry (Austin, Texas); Andrew J Robles (Austin, Texas); April L Risinger (Austin, Texas); Robert H Cichewicz (Norman, Oklahoma); Saikat Haldar (Norman, Oklahoma); Peter Houghton (Austin, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (Norman, Oklahoma) |
| INVENTOR(S) | Susan L Mooberry (Austin, Texas); Andrew J Robles (Austin, Texas); April L Risinger (Austin, Texas); Robert H Cichewicz (Norman, Oklahoma); Saikat Haldar (Norman, Oklahoma); Peter Houghton (Austin, Texas) |
| ABSTRACT | Certain embodiments are directed to methods for treating Ewing family tumors (EFT) comprising administering an effective amount of altertoxin II to a subject having EFT. |
| FILED | Wednesday, December 20, 2017 |
| APPL NO | 16/471905 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 31/336 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874643 | Baraban |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Scott C. Baraban (Novato, California) |
| ABSTRACT | Provided, inter alia, are methods for treating an epilepsy disorder using a 5HT receptor agonist, or a pharmaceutically acceptable salt thereof. |
| FILED | Wednesday, February 24, 2016 |
| APPL NO | 15/552784 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/137 (20130101) A61K 31/137 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/4184 (20130101) Original (OR) Class A61K 31/4184 (20130101) A61K 31/7048 (20130101) A61K 31/7048 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874651 | Mehrara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Babak Mehrara (Chappaqua, New York); Jason Gardenier (Altona, New York); Ira Savetsky (Cedarhurst, New York); Omer Aras (New York, New York) |
| ABSTRACT | Provided are pharmaceutical compositions and methods of treating or preventing edema, using an anti-T cell agent, an anti-TGF-β1 agent, or an anti-angiotensin agent, preferably a combination of at least two such agents. The pharmaceutical compositions can be formulated for systemic or local administration, and are preferably administered topically. |
| FILED | Friday, February 15, 2019 |
| APPL NO | 16/277942 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0014 (20130101) A61K 31/42 (20130101) A61K 31/277 (20130101) A61K 31/277 (20130101) A61K 31/401 (20130101) A61K 31/401 (20130101) A61K 31/436 (20130101) A61K 31/436 (20130101) A61K 31/4412 (20130101) Original (OR) Class A61K 31/4418 (20130101) A61K 31/4418 (20130101) A61K 38/13 (20130101) A61K 38/13 (20130101) A61K 45/06 (20130101) A61K 47/10 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874669 | Dutta |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WAYNE STATE UNIVERSITY (Detroit, Michigan) |
| ASSIGNEE(S) | WAYNE STATE UNIVERSITY (Detroit, Michigan) |
| INVENTOR(S) | Aloke K. Dutta (Troy, Michigan) |
| ABSTRACT | A compound having formula IA is useful for treating a neurodegenerative disease: or a pharmaceutically acceptable salt or ester thereof, where R0, R1, R2, R7, R8 are delineated substituents; A1 is a C6-12 aryl group, C5-12 heteroaryl group, substituted 3-hydroxypyridin-4(1H)-one, with i hydrogen atoms replaced with R7 and j hydrogen atoms replaced with R8; p is an integer from 1 to 6; X1, Y1 are each independently CH or N; M is absent or a divalent linking moiety in which Z is repeated m times; m is an integer from 0 to 5; i, j are each independently 0, 1, 2, or 3; and o is 0, 1, 2, 3, or 4. |
| FILED | Friday, September 07, 2018 |
| APPL NO | 16/124974 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/496 (20130101) A61K 31/497 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874675 | Bannister et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Thomas D. Bannister (Palm Beach Gardens, Florida); Hui Wang (Jupiter, Florida); Chao Wang (Palm Beach Gardens, Florida); John L. Cleveland (Land O'Lakes, Florida) |
| ABSTRACT | The invention provides compounds effective as inhibitors of monocarboxylate transporters such as MCT1 and MCT4, which can be used for treatment of medical conditions wherein treatment of the condition with a compound having an inhibitor effect on MCT1, MCT4, or both is medically indicated. Compounds of the invention can have antitumor, antidiabetes, anti-inflammatory, or immunosuppressive pharmacological effects, and can be effective for treatment of cancer and of type II diabetes. |
| FILED | Tuesday, May 28, 2019 |
| APPL NO | 16/423362 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/155 (20130101) A61K 31/155 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 31/525 (20130101) A61K 31/4985 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Heterocyclic Compounds C07D 475/00 (20130101) C07D 475/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874678 | DeNardo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Sally J. DeNardo (El Macero, California); Gerald L. DeNardo (El Macero, California); Rodney L. Balhorn (Livermore, California) |
| ABSTRACT | This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity. |
| FILED | Thursday, February 28, 2019 |
| APPL NO | 16/289464 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/675 (20130101) Original (OR) Class A61K 47/55 (20170801) A61K 47/60 (20170801) A61K 47/64 (20170801) A61K 47/545 (20170801) A61K 47/645 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874683 | Painter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | George R. Painter (Atlanta, Georgia); David B. Guthrie (Avondale Estates, Georgia); Gregory R. Bluemling (Decatur, Georgia); Michael R. Natchus (Alpharetta, Georgia) |
| ABSTRACT | This disclosure relates to certain N4-hydroxycytidine derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of a Zika virus infection. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 16/083177 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/008 (20130101) A61K 31/7068 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) C07H 19/067 (20130101) Technologies for Adaptation to Climate Change Y02A 50/391 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874684 | Davis |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Ian Christopher Davis (Hilliard, Ohio) |
| ABSTRACT | Compositions and method are therefore disclosed for treating ARDS. In particular, disclosed a composition that contains one, two, or more cytidine diphosphate (CDP)-conjugated precursors selected from the group consisting of CDP-choline, CDP-ethanolamine, and CDP-diacylglycerol (CDP-DAG) in a pharmaceutically acceptable carrier for use in treating ARDS. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/230225 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7068 (20130101) Original (OR) Class A61K 47/50 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874686 | Tan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Memorial Sloan-Kettering Cancer Center (New York, New York); The General Hospital Corporation (Boston, Massachusetts); East Carolina University (Greenville, North Carolina) |
| ASSIGNEE(S) | Memorial Sloan-Kettering Cancer Center (New York, New York); The General Hospital Corporation (Boston, Massachusetts); East Carolina University (Greenville, North Carolina) |
| INVENTOR(S) | Derek Shieh Tan (New York, New York); Cheng Ji (Buffalo Grove, Illinois); Indrajeet Sharma (Norman, Oklahoma); Debarshi Pratihar (Kolkata, India); James P. Coleman (Farmville, North Carolina); Everett C. Pesci (Greenville, North Carolina); Laurence G. Rahme (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are compounds of Formula (I) and pharmaceuticals acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, and prodrugs thereof. Also provided are pharmaceutical compositions, kits, and methods involving the inventive compounds for the treatment and/or of an infectious disease (e.g., bacterial infection (e.g., P. aeruginosa infection). |
| FILED | Monday, October 03, 2016 |
| APPL NO | 15/765004 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7076 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 473/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874704 | Newman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PHOENIX BIOTECHNOLOGY, INC. (San Antonio, Texas) |
| ASSIGNEE(S) | PHOENIX BIOTECHNOLOGY, INC. (San Antonio, Texas) |
| INVENTOR(S) | Robert A. Newman (Surry, Maine); Otis C. Addington (San Antonio, Texas) |
| ABSTRACT | A method of treating viral infection, such as viral infection caused by a virus of the Filoviridae family, Flaviviridae family (Flavivirus genus), Deltaretrovirus genus, or Togaviriade family is provided. A composition having at least one cardiac glycoside is used to treat viral infection. The composition can futher include at least one triterpene. Alternatively, the composition comprises at least one, at leat two, or at least three triterpenes. |
| FILED | Monday, February 03, 2020 |
| APPL NO | 16/779840 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/56 (20130101) A61K 31/7048 (20130101) A61K 36/24 (20130101) Original (OR) Class A61K 2236/37 (20130101) A61K 2236/39 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874719 | Pinsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | David J. Pinsky (Ann Arbor, Michigan); Danica Petrovic-Djergovic (Ypsilanti, Michigan) |
| ABSTRACT | The present invention provides a method of treating or preventing immunoinflammatory, vascular, thrombotic or ischemic disorders in a subject, the method comprises administering to the subject an agent which dissipates nucleotide phosphates or generates a product which stimulates adenosine receptors. The present invention also provides a method of treating or preventing immunoinflammatory, thrombotic or ischemic disorders in a subject by inhibiting leukocyte infiltration into a site which comprises administering to the subject an effective amount a described agent. Agents described for use in the methods of the invention include CD73, a fragment a mutant, or a modified form thereof. |
| FILED | Monday, January 12, 2015 |
| APPL NO | 14/594687 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) Original (OR) Class Enzymes C12Y 301/03005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874726 | Darrah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Erika Darrah (Baltimore, Maryland); Ami A. Shah (Ellicot City, Maryland); Livia A. Casciola-Rosen (Pikesville, Maryland); Antony Rosen (Pikesville, Maryland); Christine Joseph (Baltimore, Maryland); Bert Vogelstein (Baltimore, Maryland); Kenneth W. Kinzler (Baltimore, Maryland); Nickolas Papadopoulos (Towson, Maryland) |
| ABSTRACT | Autoimmune diseases are thought to be initiated by exposures to foreign antigens that cross-react with endogenous molecules. Analyses of peripheral blood lymphocytes and serum suggested that mutations in autoimmune antigen targets sparked cellular immunity and cross-reactive humoral immune responses. Acquired immunity to autoimmune antigens can help control naturally occurring cancers. |
| FILED | Thursday, December 04, 2014 |
| APPL NO | 15/101174 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0008 (20130101) Original (OR) Class A61K 2039/585 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874728 | Coukos et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | George Coukos (Wynnewood, Pennsylvania); Andrea Facciabene (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention provides methods of immunizing a subject against a tumor, inhibiting tumor growth, inhibiting tumor recurrence, treating, suppressing the growth of, or decreasing the incidence of a tumor, overcoming tolerance to a tumor vasculature marker (TVM) in a subject comprising the step of administering a vaccine comprising a TVM or a nucleic acid encoding a TVM and related vaccines. The present invention also provides a method of targeting a tumor vasculature in a subject having a tumor comprising the step of contacting said subject with a labeled compound that binds a) a tumor vasculature marker (TVM) or b) a nucleic acid molecule encoding said TVM. |
| FILED | Monday, March 21, 2016 |
| APPL NO | 15/075451 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 41/0057 (20130101) A61K 48/00 (20130101) A61K 51/1045 (20130101) A61K 2039/53 (20130101) A61K 2039/58 (20130101) A61K 2039/62 (20130101) A61K 2039/55516 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Peptides C07K 14/4748 (20130101) C07K 16/2851 (20130101) C07K 2317/24 (20130101) C07K 2319/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874729 | Hodge et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GLOBEIMMUNE, INC. (Louisville, Colorado); The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | GlobeImmune, Inc. (Louisville, Colorado); The USA, as represented by the Secretary, Dept of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | James Hodge (Kensington, Maryland); Jeffrey Schlom (Potomac, Maryland); Alex Franzusoff (Los Altos, California) |
| ABSTRACT | Disclosed are immunotherapeutic compositions and the concurrent use of combinations of such compositions for the improved induction of therapeutic immune responses and/or for the prevention, amelioration and/or treatment of disease, including, but not limited to, cancer and infectious disease. |
| FILED | Monday, July 01, 2019 |
| APPL NO | 16/458726 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/00117 (20180801) A61K 39/001102 (20180801) A61K 39/001104 (20180801) A61K 39/001106 (20180801) A61K 39/001151 (20180801) A61K 39/001152 (20180801) A61K 39/001156 (20180801) A61K 39/001157 (20180801) A61K 39/001162 (20180801) A61K 39/001164 (20180801) A61K 39/001168 (20180801) A61K 39/001182 (20180801) A61K 39/001184 (20180801) A61K 39/001186 (20180801) A61K 39/001188 (20180801) A61K 39/001191 (20180801) A61K 39/001192 (20180801) A61K 39/001194 (20180801) A61K 39/001195 (20180801) A61K 2039/523 (20130101) A61K 2039/55522 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874730 | Okada |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Hideho Okada (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided herein are interleukin-13 receptor α2 peptide-based brain cancer vaccines and methods for treating and vaccinating against brain cancer comprising administering to patients in need thereof interleukin-13 receptor α2 peptide-based brain cancer vaccines. Also provided herein are regimens comprising interleukin-13 receptor α2 peptides and at least one additional peptide and/or immunostimulant. |
| FILED | Thursday, May 28, 2015 |
| APPL NO | 14/724127 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/17 (20130101) A61K 38/17 (20130101) A61K 38/177 (20130101) A61K 38/1709 (20130101) A61K 38/1709 (20130101) A61K 38/2086 (20130101) A61K 39/0011 (20130101) A61K 39/39 (20130101) A61K 39/00115 (20180801) A61K 39/001119 (20180801) Original (OR) Class A61K 39/001122 (20180801) A61K 39/001153 (20180801) A61K 39/001192 (20180801) A61K 2039/70 (20130101) A61K 2039/572 (20130101) A61K 2039/5154 (20130101) A61K 2039/55566 (20130101) A61K 2039/55583 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Peptides C07K 14/705 (20130101) C07K 14/4703 (20130101) C07K 14/4705 (20130101) C07K 14/7155 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874737 | Narasimhan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa); University of Iowa Research Foundation (Iowa City, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa); University of Iowa Research Foundation (Iowa City, Iowa) |
| INVENTOR(S) | Balaji Narasimhan (Ames, Iowa); Kathleen A. Ross (Ames, Iowa); Kevin L. Legge (Iowa City, Iowa); Thomas J. Waldschmidt (Iowa City, Iowa) |
| ABSTRACT | Immunogenic compositions and methods of using them include a biodegradable or bioerodible polyanhydride nanoparticle comprising 1,8-bis(p-carboxyphenoxy)-3,6-dioxaoctane (CPTEG) and 1,6-bis(p-carboxyphenoxy)hexane (CPH) copolymers, an immunogenic protein of an Influenza Virus and an adjuvant entrapped within an interior of the nanoparticle, and an excipient. The immunogenic composition may be administered to a subject to confer both local and systemic immunity to the Influenza Virus. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/370444 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/51 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 39/145 (20130101) A61K 2039/525 (20130101) A61K 2039/6093 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874739 | Schnermann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The Unites States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Martin John Schnermann (Rockville, Maryland); Roger Rauhauser Nani (Frederick, Maryland); Alexander Patrick Gorka (Frederick, Maryland); Hisataka Kobayashi (Laurel, Maryland) |
| ABSTRACT | Embodiments of near-infrared light-cleavable heptamethine cyanine-based conjugates, particularly targeting agent-drug conjugates, according to Formula I and conjugate precursors are disclosed. The disclosed targeting agent-drug conjugates are useful for targeted delivery and release of a drug. Methods of making and using the conjugates and precursors also are disclosed. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 16/723482 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0042 (20130101) Original (OR) Class A61K 47/545 (20170801) A61K 47/6803 (20170801) A61K 47/6829 (20170801) A61K 47/6845 (20170801) A61K 49/0032 (20130101) A61K 49/0058 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874742 | Kaplan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tufts University (Medford, Massachusetts) |
| ASSIGNEE(S) | Tufts University (Medford, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Fiorenzo G. Omenetto (Lexington, Massachusetts); Joseph E. Brown (Somerville, Massachusetts); Rodrigo R. Jose (Medford, Massachusetts) |
| ABSTRACT | The present application relates to silk fibroin-based materials, methods for making and using the same. Provided materials exhibit shape memory characteristics while showing comparable or better volumetric swelling, biocompatibility and/or degradability when compared to current memory polymers derived from either natural or synthetic materials. |
| FILED | Friday, March 11, 2016 |
| APPL NO | 15/555225 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2017/00867 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 47/26 (20130101) A61K 47/42 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/146 (20130101) A61L 2400/16 (20130101) Peptides C07K 14/43518 (20130101) C07K 14/43586 (20130101) Derivatives of Natural Macromolecular Compounds C08H 1/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/0085 (20130101) C08J 2389/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874748 | Sun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Albert Einstein College of Medicine (Bronx, New York); Icahn School of Medicine at Mount Sinai (New York, New York); Montefiore Medical Center (Bronx, New York) |
| ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York); Icahn School of Medicine at Mount Sinai (New York, New York); Montefiore Medical Center (Bronx, New York) |
| INVENTOR(S) | Hui B. Sun (Chappaqua, New York); Evan L. Flatow (New York, New York); Tony Wanich (Englewood Cliffs, New Jersey); Konrad Gruson (New York, New York); Nelly Andarawis-Puri (New York, New York) |
| ABSTRACT | Methods for treating tendinopathy and tendonitis and for preventing tendinopathy are disclosed. |
| FILED | Friday, June 10, 2016 |
| APPL NO | 15/577470 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 48/00 (20130101) Original (OR) Class A61K 48/0091 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/386 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/066 (20130101) C12N 2501/60 (20130101) C12N 2510/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874751 | Bilgicer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Zihni Basar Bilgicer (South Bend, Indiana); Peter Edward Deak (South Bend, Indiana); Tanyel Kiziltepe Bilgicer (South Bend, Indiana); Jared Francis Stefanick (South Bend, Indiana); Jonathan Darryl Ashley (South Bend, Indiana) |
| ABSTRACT | Embodiments of the present disclosure provide a nanoparticle based platform, and nanoallergens for identifying, evaluating and studying allergen mimotopes as multiple copies of a single mimotope or various combinations on the same particle. The nanoparticle is extremely versatile and allows multivalent binding to IgEs specific to a variety of mimotopes, simulating allergen proteins. Nanoparticles can include various molecular ratios of components. For example, the nanoallergens can include about 0.1-40% mimotope-lipid conjugate and about 60-99.9% lipid. The mimotope-lipid conjugate includes a mimotope, a first linker, and lipid molecule. Nanoallergens can be used in in vitro and in vivo applications to identify a specific patient's sensitivity to a set of epitopes and predict a symptomatic clinical response, identify allergen epitopes through blind screening peptide sequences from allergen protein, and in a clinical application similar to a scratch test. |
| FILED | Monday, September 26, 2016 |
| APPL NO | 15/762260 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/1271 (20130101) A61K 39/35 (20130101) A61K 47/6911 (20170801) A61K 49/0006 (20130101) Original (OR) Class A61K 2039/60 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/40 (20130101) Enzymes C12Y 302/01052 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/586 (20130101) G01N 33/686 (20130101) G01N 33/6854 (20130101) G01N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874818 | Hassenpflug et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Philip Morris USA Inc. (Richmond, Virginia) |
| ASSIGNEE(S) | Philip Morris USA Inc. (Richmond, Virginia) |
| INVENTOR(S) | Eric Hassenpflug (Westerville, Ohio); Larry Keith Hooks, Jr. (Columbus, Ohio); James A. Prescott (Columbus, Ohio); Ludwin Mora (Columbus, Ohio); Michael Scott Ulrich (Columbus, Ohio); Jane O'Loughlin (Galloway, Ohio); Steve Wilder (Blacklick, Ohio); William G. Atterbury (Columbus, Ohio); Thomas D. Haubert (Columbus, Ohio); Ryan Somogye (Grove City, Ohio); Michael Ko (Brookline, Massachusetts); Stephen C. Schmitt (Dublin, Ohio); Michael Lorenz (Gahanna, Ohio); Lawrence A. Weinstein (Warminster, Pennsylvania); James Leamon (Warminster, Pennsylvania) |
| ABSTRACT | An aerosol delivery system, which includes an aerosol delivery unit, the aerosol delivery unit including: a cartridge receiver, which is configured to receive a cartridge assembly; and an inductor configured to receive the cartridge assembly and heat a liquid formulation within a capillary tube to produce an aerosol by induction heating. The cartridge assembly including an active part of the cartridge assembly including a capillary tube; a susceptor, the susceptor configured to partially surround the capillary tube; and a pair of displaceable covers, which surround at least the capillary tube and the susceptor. |
| FILED | Tuesday, December 26, 2017 |
| APPL NO | 15/854331 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 11/007 (20140204) A61M 11/042 (20140204) A61M 15/0003 (20140204) A61M 15/0066 (20140204) A61M 16/14 (20130101) A61M 16/0054 (20130101) A61M 16/109 (20140204) Original (OR) Class A61M 16/147 (20140204) A61M 16/0816 (20130101) A61M 2205/14 (20130101) A61M 2205/127 (20130101) A61M 2205/273 (20130101) A61M 2205/368 (20130101) A61M 2205/505 (20130101) A61M 2205/587 (20130101) A61M 2205/3368 (20130101) A61M 2205/3606 (20130101) A61M 2205/3633 (20130101) A61M 2205/6018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874847 | Halpern et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Modular Bionics Inc. (Santa Ana, California) |
| ASSIGNEE(S) | Modular Bionics Inc. (Berkeley, California) |
| INVENTOR(S) | Ian Loren Halpern (San Francisco, California); Mark William Merlo (Santa Ana, California) |
| ABSTRACT | Devices and methods for manipulating devices such as micro-scale devices are provided. The devices can include a tether of various materials surrounded by a stiff body. The tether interfaces with microscale devices to draw them against the stiff body, holding the microscale devices in a locked position for insertion into or extraction out of tissue. The tensional hook and stiff body are configurable in a multitude of positions and geometries to provide increased engagement. Such configurations allow for a range of implantation and extraction surgical procedures for the device within research and clinical settings. |
| FILED | Monday, October 01, 2018 |
| APPL NO | 16/148226 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/068 (20130101) A61B 17/076 (20130101) A61B 17/00234 (20130101) A61B 2017/00075 (20130101) A61B 2017/00345 (20130101) A61B 2017/0641 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0529 (20130101) Original (OR) Class A61N 1/3605 (20130101) A61N 1/36007 (20130101) A61N 1/36064 (20130101) A61N 1/36067 (20130101) A61N 1/36071 (20130101) A61N 1/36075 (20130101) A61N 1/36082 (20130101) A61N 1/36085 (20130101) A61N 1/36089 (20130101) A61N 1/36096 (20130101) A61N 1/36107 (20130101) A61N 1/37282 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875024 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Xiujun Li (El Paso, Texas); Maowei Dou (El Paso, Texas); Delfina Dominguez (El Paso, Texas) |
| ASSIGNEE(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Xiujun Li (El Paso, Texas); Maowei Dou (El Paso, Texas); Delfina Dominguez (El Paso, Texas) |
| ABSTRACT | Certain embodiments are directed to paper and its hybrid microfluidic devices integrated with nucleic acid amplification for simple, cost-effective, rapid, and sensitive pathogen detection, especially in low-resource settings. |
| FILED | Friday, July 10, 2015 |
| APPL NO | 14/796127 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5027 (20130101) B01L 3/50851 (20130101) Original (OR) Class B01L 3/502715 (20130101) B01L 7/52 (20130101) B01L 2200/0605 (20130101) B01L 2300/126 (20130101) B01L 2300/0636 (20130101) B01L 2300/0681 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/0887 (20130101) B01L 2300/0893 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) C12Q 1/6865 (20130101) C12Q 1/6865 (20130101) C12Q 1/6867 (20130101) C12Q 1/6867 (20130101) C12Q 2563/107 (20130101) C12Q 2563/107 (20130101) C12Q 2565/601 (20130101) C12Q 2565/601 (20130101) C12Q 2565/629 (20130101) C12Q 2565/629 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875766 | Acosta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victor Acosta (Albuquerque, New Mexico); Andrejs Jarmola (Albany, California) |
| ABSTRACT | Technologies related to parallel characterization of individual MNPs are disclosed. A diamond chip with MNPs distributed thereon may be used with an epifluorescence microscope and camera to generate multiple different images of multiple individual MNPs. The multiple images are recorded at different microwave frequencies and under different external magnetic field strengths. The multiple images are then used to determine properties of the multiple individual MNPs. |
| FILED | Friday, October 27, 2017 |
| APPL NO | 16/343590 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/009 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 35/00 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1031 (20130101) G01N 2015/0038 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/1223 (20130101) G01R 33/1269 (20130101) G01R 33/1276 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875822 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Jin-quan Yu (San Diego, California); Ru-yi Zhu (San Diego, California) |
| ABSTRACT | This invention discloses the first example of palladium(II)-catalyzed β-C(sp3)-H iodination or arylation of a wide range of ketones by using a commercially available aminooxyacetic acid auxiliary. This L, X-type directing group overcomes the limitation of the transient directing group approach for -βC(sp3)-H functionalization of ketones. Practical advantages of this method include simple installation of the auxiliary without chromatography, exceptional tolerance of a-functional groups, double bonds and triple bonds and rapid access to diverse sterically hindered quaternary centers. |
| FILED | Monday, August 13, 2018 |
| APPL NO | 16/639401 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2226 (20130101) B01J 2531/0219 (20130101) B01J 2531/824 (20130101) Acyclic or Carbocyclic Compounds C07C 45/42 (20130101) Original (OR) Class C07C 49/233 (20130101) C07C 249/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875834 | Safo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| ASSIGNEE(S) | Virginia Commonwealth University (Richmond, Virginia); The Children's Hospital of Philadelphia (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Martin K. Safo (Richmond, Virginia); Guoyan Xu (Richmond, Virginia); Yan Zhang (Richmond, Virginia); Osheiza Abdulmalik (Richmond, Virginia) |
| ABSTRACT | Prodrugs and derivatives of 5-hydoxymethyl-2-furfural (5-HMF) with protected or modified aldehyde and/or alcohol moieties are provided. The prodrugs or derivatives exhibit increased bioavailability, e.g. due to having extended half-lives in circulation. The drugs are therefore administered i) at lower doses and/or ii) less frequently than 5-HMF, while still maintaining the beneficial therapeutic effects of 5-HMF. |
| FILED | Monday, July 24, 2017 |
| APPL NO | 16/318590 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) A61P 43/00 (20180101) Heterocyclic Compounds C07D 307/46 (20130101) Original (OR) Class C07D 417/04 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/65515 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875839 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Crinetics Pharmaceuticals, Inc. (San Diego, California) |
| ASSIGNEE(S) | CRINETICS PHARMACEUTICALS, INC. (San Diego, California) |
| INVENTOR(S) | Jian Zhao (San Diego, California); Shimiao Wang (San Diego, California); Yunfei Zhu (San Diego, California) |
| ABSTRACT | Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity. |
| FILED | Thursday, December 12, 2019 |
| APPL NO | 16/712620 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 401/04 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 405/14 (20130101) C07D 413/14 (20130101) C07D 471/04 (20130101) C07D 498/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875840 | Fox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph Fox (Landenberg, Pennsylvania); Xinqiao Jia (Newark, Delaware); Will Trout (Wilmington, Delaware); Joel Rosenthal (Newark, Delaware); Han Zhang (Columbia, Maryland); Yinzhi Fang (Newark, Delaware); Colin Thorpe (Newark, Delaware); Shuang Liu (Newark, Delaware); Yixin Xie (Newark, Delaware) |
| ASSIGNEE(S) | UNIVERSITY OF DELAWARE (Newark, Delaware) |
| INVENTOR(S) | Joseph Fox (Landenberg, Pennsylvania); Xinqiao Jia (Newark, Delaware); Will Trout (Wilmington, Delaware); Joel Rosenthal (Newark, Delaware); Han Zhang (Columbia, Maryland); Yinzhi Fang (Newark, Delaware); Colin Thorpe (Newark, Delaware); Shuang Liu (Newark, Delaware); Yixin Xie (Newark, Delaware) |
| ABSTRACT | A method for catalytically converting a dihydrotetrazine 1 into a tetrazine 2, wherein one R group on the dihydrotetrazine 1 is a substituted or unsubstituted aryl, heteroaryl, alkyl, alkenyl, alkynyl, carbonyl, or heteroatom-containing group, and the other R group is selected from the group consisting of H and substituted or unsubstituted aryl, heteroaryl, alkyl, alkenyl, alkynyl, carbonyl,- or heteroatom-containing groups; 1, 2 wherein the method comprises oxidizing dihydrotetrazine 1 in a reaction medium in the presence of a catalyst and a stoichiometric oxidant. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 16/062423 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 257/08 (20130101) C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 403/04 (20130101) C07D 403/14 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/165 (20130101) Enzymes C12Y 111/01007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875844 | Gray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Tinghu Zhang (Brookline, Massachusetts); Hai-Tsang Huang (Boston, Massachusetts); Yubao Wang (Newton, Massachusetts); Jean Zhao (Brookline, Massachusetts); Hwan Geun Choi (Seoul, South Korea) |
| ABSTRACT | Provided herein are small molecule inhibitors of maternal embryonic leucine zipper kinase (MELK) having the structure of formula (I), wherein X and R1-R3 are defined in the specification. The compounds are useful for treating cancer and other conditions or diseases associated with aberrant MELK expression. Also provided herein are pharmaceutical compositions comprising a compound of formula (I) and a pharmaceutically acceptable carrier. The invention also provides methods of treating cancers associated with over-expression of MELK. |
| FILED | Friday, March 04, 2016 |
| APPL NO | 15/554753 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/337 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 223/16 (20130101) C07D 231/12 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) Original (OR) Class C07D 403/14 (20130101) C07D 413/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875860 | Cushman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | PURDUE RESEARCH FOUNDATION (West Lafayette, Indiana); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Mark S. Cushman (West Lafayette, Indiana); Ping Wang (Vestavia Hills, Alabama); Yves George Pommier (Bethesda, Maryland); Mohamed S. A. Elsayed (Urbana, Illinois) |
| ABSTRACT | Tyrosyl-DNA Phosphodiesterases 1 and 2 (Tdp1 and Tdp2) can repair damaged DNA resulting from topoisomerase inhibitors (e.g. Top1) and a variety of other DNA-damaging agents. 7-Azaindenoisoquinolines that are inhibitors of each of Top1, Tdp1 and Tdp2 are disclosed. Also described are methods for preparing azaindenoisoquinoline and methods for treating patients of a cancer using the disclosed azaindenoisoquinoline compounds or a pharmaceutical formulation thereof. |
| FILED | Tuesday, December 19, 2017 |
| APPL NO | 16/471945 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875890 | Sikora et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon); The University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Aleksandra Sikora (Corvallis, Oregon); Konstantin V. Korotkov (Lexington, Kentucky) |
| ABSTRACT | Disclosed herein are peptide inhibitors of AniA. Pharmaceutical compositions are also disclosed that include one or more peptide inhibitors of AniA and/or nucleic acids encoding the same. The pharmacological inhibition of AniA should disable anaerobic respiration and augment the ability of existing antimicrobials to clear the pathogen. Thus, also disclosed are methods of inhibiting and/or treating infection from N. gonorrhoeae. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 16/489707 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/08 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875904 | Schmitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| ASSIGNEE(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| INVENTOR(S) | Thomas M. Schmitt (Seattle, Washington); Philip D. Greenberg (Mercer Island, Washington) |
| ABSTRACT | The present disclosure provides methods for generating enhanced affinity T cell receptors by agonist selection of hematopoietic progenitor cells expressing an antigen specific TCRα cultured with stromal cells expressing Delta-like-1 or Delta-like-4, compositions prepared from such methods, and uses of thereof. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 15/692846 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/1774 (20130101) A61K 39/0011 (20130101) A61K 39/001153 (20180801) A61K 39/001168 (20180801) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/7051 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/065 (20130101) C12N 5/0636 (20130101) C12N 2501/42 (20130101) C12N 2502/99 (20130101) C12N 2502/1394 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) G01N 2333/7051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875907 | Lai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York); THE GOVERNING COUNCEL OF THE UNIVERSITY OF TORONTO (Toronto, Canada); THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY (Fort Detrick, Maryland) |
| ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York); The Governing Council of the University of Toronto (Toronto, Canada); The Government of the United States as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Jonathan R. Lai (Dobbs Ferry, New York); Jayne F. Koellhoffer (New York, New York); Julia Frei (Bronx, New York); Kartik Chandran (Brooklyn, New York); Sachdev Sidhu (Toronto, Canada); Gang Chen (Toronto, Canada); John M. Dye (Frederick, Maryland); Samantha Zak (Frederick, Maryland) |
| ABSTRACT | The present invention addresses a need for antibodies useful for filovirus infections. |
| FILED | Tuesday, September 18, 2018 |
| APPL NO | 16/134041 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 16/24 (20130101) C07K 2317/24 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875923 | Dong |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Haidong Dong (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials for detecting B7-H1 polypeptides (e.g., soluble B7-H1 polypeptides). For example, antibodies (e.g., monoclonal antibodies) that bind to a B7-H1 polypeptide (e.g., a soluble B7-H1 polypeptide) are provided. |
| FILED | Wednesday, October 26, 2016 |
| APPL NO | 15/772351 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/2827 (20130101) Original (OR) Class C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875927 | Press et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| ASSIGNEE(S) | FRED HUTCHINSON CANCER RESEARCH CENTER (Seattle, Washington) |
| INVENTOR(S) | Oliver Press (Seattle, Washington); Brian Till (Seattle, Washington) |
| ABSTRACT | The present disclosure provides compositions and uses thereof for treating a disease or disorder associated with CD20 expression. Treatments of this disclosure include use of a host cell expressing a fusion protein, such as an anti-CD20 CAR, optionally in combination with a CD20-specific binding molecule, a chemotherapeutic, an inhibitor of an immunosuppression component, or combinations thereof. |
| FILED | Friday, March 17, 2017 |
| APPL NO | 16/086290 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/001124 (20180801) A61K 39/39541 (20130101) A61K 39/39558 (20130101) A61K 39/39558 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2039/5156 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 16/2887 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/73 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875970 | Compel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (Fort Collins, Colorado) |
| ASSIGNEE(S) | Colorado State University Research Foundation (Fort Collins, Colorado) |
| INVENTOR(S) | William Scott Compel (Fort Collins, Colorado); Christopher J. Ackerson (Fort Collins, Colorado); O. Andrea Wong (Madison, Wisconsin) |
| ABSTRACT | The invention provides a metallopolymer coordination network comprising one or more coinage or similar metals and a glyme or glyme-equivalent. The composition has an amorphous polymer network that is significantly stronger than previously reported supramolecular hydrogels synthesized without glyme. Glyme chain length and water content strongly influence the mechanical, electronic, and optical behavior of the network. |
| FILED | Thursday, November 21, 2019 |
| APPL NO | 16/690745 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 79/00 (20130101) Original (OR) Class C08G 2210/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 2385/00 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/52 (20130101) Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 9/02 (20130101) C09J 185/00 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/052 (20130101) H01M 10/056 (20130101) H01M 10/0525 (20130101) H01M 10/0565 (20130101) H01M 2300/0085 (20130101) H01M 2300/0088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876003 | Schnermann et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Martin John Schnermann (Rockville, Maryland); Roger Rauhauser Nani (Frederick, Maryland); James Blaine Shaum (Frederick, Maryland) |
| ABSTRACT | Embodiments of C4′-alkyl-ether heptamethine cyanine fluorophores according to general formula I, and pharmaceutically acceptable salts thereof, are disclosed. Methods of making and using the C4′-alkyl-ether heptamethine cyanine fluorophores also are disclosed. |
| FILED | Wednesday, April 03, 2019 |
| APPL NO | 16/374642 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0032 (20130101) Heterocyclic Compounds C07D 209/10 (20130101) C07D 209/12 (20130101) C07D 209/14 (20130101) Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 23/086 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1018 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876088 | Griffith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Linda Griffith (Cambridge, Massachusetts); David Trumper (Plaistow, New Hampshire); Collin Edington (Cambridge, Massachusetts); Gaurav Rohatgi (Boston, Massachusetts); Duncan Freake (Boston, Massachusetts); Luis Soenksen (Boston, Massachusetts); Mohan Brij Bhushan (Cambridge, Massachusetts) |
| ABSTRACT | Fluidic multiwell bioreactors are provided as a microphysiological platform for in vitro investigation of multi-organ crosstalks for an extended period of time of at least weeks and months. The disclosed platform is featured with one or more improvements over existing bioreactors, including on-board pumping for pneumatically driven fluid flow, a redesigned spillway for self-leveling from source to sink, a non-contact built-in fluid level sensing device, precise control on fluid flow profile and partitioning, and facile reconfigurations such as daisy chaining and multilayer stacking. The platform supports the culture of multiple organs in a microphysiological, interacted systems, suitable for a wide range of biomedical applications including systemic toxicity studies and physiology-based pharmacokinetic and pharmacodynamic predictions. A process to fabricate the disclosed bioreactors is also provided. |
| FILED | Monday, February 06, 2017 |
| APPL NO | 15/425858 |
| ART UNIT | 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 3/502738 (20130101) B01L 2200/0621 (20130101) B01L 2300/0829 (20130101) B01L 2300/0887 (20130101) B01L 2400/086 (20130101) B01L 2400/0406 (20130101) B01L 2400/0457 (20130101) B01L 2400/0487 (20130101) B01L 2400/0655 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) Original (OR) Class C12M 25/14 (20130101) C12M 29/10 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 19/006 (20130101) F04B 23/04 (20130101) F04B 23/06 (20130101) F04B 43/12 (20130101) F04B 43/043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876100 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Broad Institute Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE BROAD INSTITUTE, INC. (Cambridge, Massachusetts); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Feng Zhang (Cambridge, Massachusetts); Linyi Gao (Cambridge, Massachusetts); Bernd Zetsche (Gloucester, Massachusetts); Ian Slaymaker (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed and claimed are mutation(s) or modification(s) of the CRISPR enzyme, for example a Cas enzyme such as a Cas9, which obtain an improvement, for instance a reduction, as to off-target effects of a CRISPR-Cas or CRISPR-enzyme or CRISPR-Cas9 system or complex containing or including such a mutated or modified Cas or CRISPR enzyme or Cas9. Methods for making and using and uses of such mutated or modified Cas or CRISPR enzyme or Cas9 and systems or complexes containing the same and products from such methods and uses are also disclosed and claimed. |
| FILED | Saturday, December 16, 2017 |
| APPL NO | 15/844528 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 2319/09 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/111 (20130101) C12N 15/902 (20130101) C12N 2310/20 (20170501) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876111 | Shlomchik et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Mark Shlomchik (Pittsburgh, Pennsylvania); Adriana Turqueti Neves (Olching, Germany); Eduardo Schittler Neves (Olching, Germany); Constantinos George Panousis (Pittsburgh, Pennsylvania); Alexander McIntyre Rowe (Pittsburgh, Pennsylvania) |
| ABSTRACT | This document provides methods and materials involved in cloning functional TCRs from single T cells. For example, methods and materials for obtaining nucleic acid encoding a TCR from a single T cell and arranging that nucleic acid to form nucleic acid vectors successfully designed to express a TCR, kits for obtaining nucleic acid encoding a TCR from a single T cell and arranging that nucleic acid to form nucleic acid vectors successfully designed to express a TCR, methods for making such kits, collections of nucleic acid primers designed to amplify the entire coding sequence of both variable regions for each expressed V segment for functional αβ or γδ TCRs of a particular mammalian species, methods for using such collections of nucleic acid primers to clone functional TCRs from single T cells, and kits containing such collections of nucleic acid primers to clone functional TCRs from single T cells are provided. |
| FILED | Wednesday, November 29, 2017 |
| APPL NO | 15/826671 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/7051 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 15/1096 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 2525/143 (20130101) C12Q 2549/119 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876116 | Webb et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Carol F. Webb (Oklahoma City, Oklahoma); Julie Ward (Franklin, Massachusetts); Michelle Ratliff (Oklahoma City, Oklahoma) |
| ABSTRACT | Antisense compounds for suppressing expression of ARTD3a are disclosed, as well as pharmaceutical compositions containing same and methods of producing and using same. The antisense compounds can be used to treat inflammatory disorders and conditions related to interferon-alpha production. |
| FILED | Friday, July 14, 2017 |
| APPL NO | 16/317719 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) A61P 37/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/314 (20130101) C12N 2310/351 (20130101) C12N 2310/3233 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876118 | Lois-Caballe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Carlos Lois-Caballe (Cambridge, Massachusetts); David Baltimore (Pasadena, California); Xiao-Feng Qin (Sugarland, Texas); Irvin S. Y. Chen (Palos Verdes Estates, California); Dong Sung An (Los Angeles, California) |
| ABSTRACT | In one aspect, the invention provides methods and compositions for the expression of small RNA molecules within a cell using a retroviral vector (FIG. 1A). Small interfering RNA (siRNA) can be expressed using the methods of the invention within a cell. In a further aspect, the invention provides methods for producing siRNA encoding lentivirus where the siRNA activity may interfere with the lentiviral life cycle. In yet a further aspect, the invention provides methods for expression of a small RNA molecule within a cell, such as an siRNA capable of downregulating CCR5, wherein expression of the small RNA molecule is relatively non-cytotoxic to the cell. The invention also includes small RNA molecules, such as an siRNA capable of downregulating CCR5, that are relatively non-cytotoxic to cells. |
| FILED | Thursday, July 05, 2018 |
| APPL NO | 16/028262 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/86 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/1132 (20130101) Original (OR) Class C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/111 (20130101) C12N 2330/30 (20130101) C12N 2740/16043 (20130101) C12N 2740/16045 (20130101) C12N 2760/20122 (20130101) C12N 2799/027 (20130101) C12N 2810/609 (20130101) C12N 2830/003 (20130101) C12N 2830/008 (20130101) C12N 2830/48 (20130101) C12N 2840/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876120 | Wucherpfennig et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | DANA-FARBER CANCER INSTITUTE, INC (Boston, Massachusetts); THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Kai W. Wucherpfennig (Brookline, Massachusetts); Glenn Dranoff (Sudbury, Massachusetts); Penghui Zhou (Quincy, Massachusetts); Donald Shaffer (Boston, Massachusetts); Nir Hacohen (Brookline, Massachusetts); Harvey I. Cantor (Wellesley, Massachusetts); Diana Alvarez Arias (Midland, Michigan) |
| ABSTRACT | The present disclosure provides, in part, methods of discovering immunotherapy targets in vivo, therapeutic compositions (e.g., shRNA, immunoresponsive cells expressing shRNA and/or a chimeric antigen receptors (CAR)), and methods of use thereof. |
| FILED | Tuesday, April 03, 2018 |
| APPL NO | 15/944330 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 39/0011 (20130101) A61K 39/001195 (20180801) A61K 2039/585 (20130101) A61K 2039/5158 (20130101) Peptides C07K 14/7051 (20130101) C07K 16/32 (20130101) C07K 2317/24 (20130101) C07K 2317/55 (20130101) C07K 2317/76 (20130101) C07K 2317/622 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) C12N 15/113 (20130101) C12N 15/1137 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/531 (20130101) C12N 2320/31 (20130101) C12N 2320/32 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876123 | Kochenderfer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America,as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | James N. Kochenderfer (Bethesda, Maryland) |
| ABSTRACT | The invention provides an isolated and purified nucleic acid sequence encoding a chimeric antigen receptor (CAR) directed against B-cell Maturation Antigen (BCMA). The invention also provides host cells, such as T-cells or natural killer (NK) cells, expressing the CAR and methods for destroying multiple myeloma cells. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/683543 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/18 (20130101) C07K 16/2878 (20130101) C07K 2317/73 (20130101) C07K 2319/00 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876133 | Lois-Caballe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Carlos Lois-Caballe (Cambridge, Massachusetts); David Baltimore (Pasadena, California); Xiao-Feng Qin (Sugarland, Texas) |
| ABSTRACT | The invention provides methods and compositions for the expression of small RNA molecules within a cell using a lentiviral vector. The methods can be used to express doubles stranded RNA complexes. Small interfering RNA (siRNA) can be expressed using the methods of the invention within a cell, which is capable of down regulating the expression of a target gene through RNA interference. A variety of cells can be treated according to the methods of the invention including embryos, embryogenic stem cells, allowing for the generation of transgenic animals or animals constituted partly by the transduced cells that have a specific gene or a group of genes down regulated. |
| FILED | Tuesday, April 03, 2018 |
| APPL NO | 15/944562 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 15/867 (20130101) C12N 15/1132 (20130101) C12N 15/1138 (20130101) C12N 2310/14 (20130101) C12N 2310/53 (20130101) C12N 2310/111 (20130101) C12N 2310/531 (20130101) C12N 2330/30 (20130101) C12N 2740/15043 (20130101) C12N 2740/16043 (20130101) C12N 2830/003 (20130101) C12N 2830/006 (20130101) C12N 2830/008 (20130101) C12N 2830/30 (20130101) C12N 2830/48 (20130101) C12N 2830/60 (20130101) C12N 2830/85 (20130101) C12N 2840/20 (20130101) C12N 2840/203 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876142 | Söll et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Dieter Söll (Guilford, Connecticut); Caroline Aldag (Mannheim, Germany); Michael Hohn (Scotch Plains, New Jersey); Takahito Mukai (New Haven, Connecticut) |
| ABSTRACT | Non-naturally occurring tRNASec and methods of using them for recombinant expression of proteins engineered to include one or more selenocysteine residues are disclosed. The non-naturally occurring tRNASec can be used for recombinant manufacture of selenocysteine containing polypeptides encoded by mRNA without the requirement of an SECIS element. In some embodiments, selenocysteine containing polypeptides are manufactured by co-expressing a non-naturally occurring tRNASec a recombinant expression system, such as E. coli, with SerRS, EF-Tu, SelA, or PSTK and SepSecS, and an mRNA with at least one codon that recognizes the anticodon of the non-naturally occurring tRNASec. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/724678 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/113 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876143 | Swarts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Central Michigan University (Mount Pleasant, Michigan); University of Maine System (Bangor, Maine) |
| ASSIGNEE(S) | Central Michigan University (Mount Pleasant, Michigan); University of Maine System (Bangor, Maine) |
| INVENTOR(S) | Benjamin M. Swarts (Mount Pleasant, Michigan); Peter Woodruff (Portland, Maine) |
| ABSTRACT | The present invention provides methods of synthesizing trehalose analogues; methods of detecting mycobacteria, and trehalose analogues. |
| FILED | Monday, December 18, 2017 |
| APPL NO | 15/845555 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/00 (20130101) C07H 3/04 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/12 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/35 (20130101) G01N 2333/91102 (20130101) G01N 2400/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876151 | Sundaresan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Tilak K. Sundaresan (Jamaica Plain, Massachusetts); Zongli Zheng (Hong Kong, China PRC); Daniel A. Haber (Chestnut Hill, Massachusetts); Shyamala Maheswaran (Lexington, Massachusetts); A. John Iafrate (Newton, Massachusetts) |
| ABSTRACT | Ultra-sensitive assays for the detection of mutations, e.g., from blood-based sources of tumor genetic material (circulating tumor cells or plasma), or other settings in which limiting amounts of DNA, e.g., tumor DNA, is available. The assay is exemplified in the estrogen receptor, but is broadly customizable to target mutations in other genes. |
| FILED | Friday, April 15, 2016 |
| APPL NO | 15/566116 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1058 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6827 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 2525/161 (20130101) C12Q 2525/191 (20130101) C12Q 2531/113 (20130101) C12Q 2535/122 (20130101) C12Q 2549/126 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876157 | Drndic et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of The University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Marija Drndic (Philadelphia, Pennsylvania); Ken Healy (Auburn, Alabama); Vishva Ray (Ann Arbor, Michigan); Lauren J. Willis (Philadelphia, Pennsylvania); Neil Peterman (Cambridge, Massachusetts); John Bartel (Palo Alto, California) |
| ABSTRACT | Disclosed are insulated nanoelectrode associated with nanopores, useful in macromolecular analysis devices. Also disclosed are related methods of fabrication and use. |
| FILED | Thursday, September 26, 2013 |
| APPL NO | 14/429655 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6869 (20130101) Original (OR) Class C12Q 1/6869 (20130101) C12Q 2565/631 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/34 (20130101) C23C 16/45525 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/40 (20130101) G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876177 | Koussa et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Mounir Ahmad Koussa (Somerville, Massachusetts); Wesley Philip Wong (Cambridge, Massachusetts) |
| ABSTRACT | Provided are methods and compositions relating to conjugation of nucleic acids and proteins of interest under conditions that maintain protein activity. The nucleic acid-protein conjugates may be used in nucleic acid nanostructures such as those generated using DNA origami methods. |
| FILED | Thursday, July 10, 2014 |
| APPL NO | 14/903463 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/65 (20170801) Peptides C07K 1/1077 (20130101) C07K 7/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/96 (20130101) Enzymes C12Y 304/22044 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876942 | Wikswo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Philip C. Samson (Nashville, Tennessee) |
| ABSTRACT | A system for applying and measuring tensions of a plurality of bio-object constructs includes a base; and a flexible body disposed on the base, wherein the flexible body defines a plurality of construct holes for accommodating the plurality of bio-object constructs, such that when the flexible body is bent, the bending of the flexible body causes tensions to be applied to the plurality of bio-object constructs, thereby causing displacements of the plurality of bio-object constructs. |
| FILED | Wednesday, July 22, 2020 |
| APPL NO | 16/935457 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/20 (20130101) Original (OR) Class G01N 2203/028 (20130101) G01N 2203/0089 (20130101) G01N 2203/0094 (20130101) G01N 2203/0647 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0004 (20130101) G02B 21/08 (20130101) G02B 21/26 (20130101) G02B 21/365 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876955 | Welsh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Joshua Aden Welsh (North Bethesda, Maryland); Jennifer C. Jones (Bethesda, Maryland); William G. Telford (Bethesda, Maryland); Jay A. Berzofsky (Bethesda, Maryland); Ari Rosner (Edgewater, Maryland) |
| ABSTRACT | Apparatus include an illumination source configured to produce and direct a multi-wavelength illumination beam to a microfluidic target that can include nanotags, a detector configured to receive a multi-wavelength detection beam from the microfluidic target and to produce a detection signal, wherein the multi-wavelength detection beam comprises light that is elastically side-scattered by an interaction between the multi-wavelength illumination beam and the nanotags in the microfluidic target, and a processor configured to receive the detection signal and to determine the presence of the nanotags in the microfluidic target by comparing multiple wavelength side-scatter intensity characteristics of the detection signal with predetermined multi-wavelength elastic side-scatter intensity profiles of one or more nanotag types. Methods are also disclosed that determine the presence of different nanotags responsive to a multi-wavelength detection beam based on a detected signal and predetermined multi-wavelength elastic side-scatter intensity profiles for different nanotag types. |
| FILED | Tuesday, October 23, 2018 |
| APPL NO | 16/756420 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) Original (OR) Class G01N 15/1459 (20130101) G01N 2015/1006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876971 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Chenxiang Lin (Cambridge, Massachusetts); Chao Li (Boston, Massachusetts); William M. Shih (Cambridge, Massachusetts); Peng Yin (Brookline, Massachusetts); Ralf Jungmann (Munich, Germany) |
| ABSTRACT | Provided herein are, inter alia, barcode probes comprised of transiently or stably fluorescently labeled nucleic acid nanostructures that are fully addressable and able to be read using standard fluorescent microscope and methods of use thereof including methods of use as detectable labels for probes. |
| FILED | Thursday, June 14, 2018 |
| APPL NO | 16/008719 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 2563/107 (20130101) C12Q 2563/157 (20130101) C12Q 2563/185 (20130101) C12Q 2565/102 (20130101) C12Q 2565/601 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876972 | Yang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shan Yang (Madison, Mississippi) |
| ASSIGNEE(S) | Jackson State University (Jackson, Mississippi) |
| INVENTOR(S) | Shan Yang (Madison, Mississippi) |
| ABSTRACT | An improved hyperspectral Raman imaging system and device that obtains full scale Raman images from a sample surface in seconds, wherein the dichromic mirror is located between the objective lens and sample surface. The laser is delivered to the sample surface and the Raman image is collected and transmitted through optic fiber to a camera after filtration. By delivering the laser to the sample without going through the objective lens, a high-power laser can safely illuminate the full field of view of the objective lens, allowing for safe Raman imaging within seconds. This fast and safe Raman imaging system can be used for, among other applications, the early detection of dental caries in practical settings. |
| FILED | Thursday, May 30, 2019 |
| APPL NO | 16/426959 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/44 (20130101) G01J 3/0224 (20130101) G01J 3/2823 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 2201/06113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876980 | Sung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Industry and Academic Cooperation In Chungnam National University (IAC) (Daejeon, South Korea) |
| ASSIGNEE(S) | THE INDUSTRY and ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC) (Daejeon, South Korea) |
| INVENTOR(S) | Yung-Eun Sung (Seoul, South Korea); Jungjin Park (Seoul, South Korea); Chunjoong Kim (Daejeon, South Korea); Jong Sig Lee (Gyeonggi-do, South Korea); Jae-Hyuk Park (Incheon, South Korea) |
| ABSTRACT | Provided is an in-situ X-ray analysis apparatus including a potentiostat connected to an in-situ electrochemical cell and configured to adjust voltage, current, and time of the in-situ electrochemical cell or to record information regarding voltage, current, resistance, capacity, and time information of the in-situ electrochemical cell; an X-ray analysis apparatus configured to obtain X-ray diffraction information regarding the in-situ electrochemical cell; and a controller connected to the X-ray analysis apparatus and the potentiostat and configured to provide or receive signals to or from the X-ray analysis apparatus and the potentiostat. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/263495 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/207 (20130101) Original (OR) Class G01N 23/20025 (20130101) G01N 2223/60 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877026 | Knipp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Gregory T. Knipp (West Lafayette, Indiana); Aimable Ngendahimana (West Lafayette, Indiana); Christopher D. Kulczar (Bremen, Indiana); Kelsey E. Lubin (Lafayette, Indiana); Monika Lavan (Lafayette, Indiana) |
| ABSTRACT | The present disclosure generally relates to a process to prepare a cell culture system that mimics the structure of blood brain barrier (BBB) and are useful to study the functions thereof. In particular, the present invention relates to a direct-contact coculture and triculture systems prepared by plating BMECs on a pre-formed lawn of coculture of astrocytes and pericytes on the apical surface of a culture-chamber to achieve a truly direct contact triculture model for BBB. The cell culture systems disclosed herein are also useful for studying the functions of the blood brain barrier and predicting the efficacy and potential toxicity of a drug candidate. |
| FILED | Thursday, September 07, 2017 |
| APPL NO | 15/697699 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0618 (20130101) C12N 5/0622 (20130101) C12N 5/0697 (20130101) C12N 2502/28 (20130101) C12N 2502/086 (20130101) C12N 2533/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) G01N 33/5058 (20130101) G01N 33/5082 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877037 | Ibrahim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (Torrance, California) |
| ASSIGNEE(S) | LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE AT HARBOR-UCLA MEDICAL CENTER (Torrance, California) |
| INVENTOR(S) | Ashraf S. Ibrahim (Torrance, California); Sameh Soliman (Torrance, California); John Edwards, Jr. (Torrance, California) |
| ABSTRACT | Presented herein, in certain aspects, are compositions that comprise novel toxin proteins, the nucleic acids that encode them, and/or portions thereof, which toxins are expressed by fungi of the Mucorales order and are thought to contribute to the pathogenesis of Mucormycosis. Also presented herein, in certain aspects, are methods of detecting the presence or absence of novel fungal toxins and/or the nucleic acids that encode them in a sample, which methods can be used to identify the presence of Mucorales in a subject. Methods and/or compositions presented herein can be used to prevent and/or treat a Mucorales infection. |
| FILED | Monday, November 20, 2017 |
| APPL NO | 16/462511 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0002 (20130101) A61K 39/0011 (20130101) A61K 39/39 (20130101) A61K 2039/505 (20130101) A61K 2039/585 (20130101) A61K 2039/55505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/00 (20180101) A61P 31/10 (20180101) A61P 35/00 (20180101) Peptides C07K 14/37 (20130101) C07K 16/14 (20130101) C07K 2317/76 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6895 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56961 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877049 | Bielekova et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Montana State University (Bozeman, Montana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); Montana State University (Bozeman, Montana) |
| INVENTOR(S) | Bibiana Bielekova (Kensington, Maryland); Mika Komori (Bethesda, Maryland); Peter Kosa (Bethesda, Maryland); Mark C. Greenwood (Bozeman, Montana); Christopher Barbour (Bozeman, Montana) |
| ABSTRACT | Biomarkers associated with neuroimmunological disease are described. The disclosed biomarkers are secreted proteins identified in cerebral spinal fluid (CSF) samples of patients with neurological disease. The disclosed biomarkers identify patients with intrathecal inflammation, distinguish multiple sclerosis (MS) patients from patients with other types of inflammatory neurological diseases and from subjects without MS, distinguish progressive MS patients from patients with relapsing-remitting MS, identify subjects with non-MS inflammatory neurological diseases, differentiate healthy subjects from patients with any type of neurological disease, and/or identify subjects with increased disability, CNS tissue damage and/or neurodegeneration. Process-specific biomarkers that can be used in place of a brain biopsy to identify immune cell infiltration and/or activation in the CNS are also described. Methods of treating subject with neurological disease, and methods of evaluating the efficacy of particular treatments, based on detection of the disclosed biomarkers are also described. |
| FILED | Monday, February 25, 2019 |
| APPL NO | 16/284914 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) Original (OR) Class G01N 2333/705 (20130101) G01N 2800/52 (20130101) G01N 2800/60 (20130101) G01N 2800/285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877120 | McGivney et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Debra McGivney (Bay Village, Ohio); Mark A. Griswold (Shaker Heights, Ohio) |
| ABSTRACT | A method for magnetic resonance fingerprinting (MRF), including accessing MRF data and a dictionary of signal evolutions. A plurality of regions-of-interest (ROIs) are selected in the MRF data. A first series of tissue parameter estimates is generated from the MRF data in the ROIs using the dictionary and a multicomponent Bayesian framework. From the first series of tissue parameter estimates, probability distributions are computed for different tissue types. The method further includes creating a reduced dictionary by removing entries from the dictionary having tissue parameter values not contained within the computed probability distributions. A second series of tissue parameter estimates is generated from the MRF data using the reduced dictionary and a multicomponent Bayesian framework. The method also includes generating a tissue probability map for each different tissue type from the second series of tissue parameter estimates. |
| FILED | Monday, May 20, 2019 |
| APPL NO | 16/416666 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) Original (OR) Class G01R 33/543 (20130101) G01R 33/5608 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877121 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Dan Ma (Solon, Ohio); Mark A. Griswold (Shaker Heights, Ohio) |
| ABSTRACT | A method for magnetic resonance fingerprinting (MRF) with reduced acoustic noise includes accessing a MRF dictionary using a magnetic resonance imaging (MRI) system, acquiring MRF data using the MRI system and a pulse sequence comprising a plurality of arbitrary gradient waveforms for each gradient axis and random repetition times to control acoustic noise, comparing the MRF data to the MRF dictionary to identify at least one parameter of the MRF data and generating a report indicating the at least one parameter of the MRF data. |
| FILED | Monday, May 20, 2019 |
| APPL NO | 16/416811 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/543 (20130101) G01R 33/4828 (20130101) G01R 33/5608 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10878939 | Sadhasivam |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | Senthilkumar Sadhasivam (Mason, Ohio) |
| ABSTRACT | The invention provides methods, kits and systems related to personalized pain management. |
| FILED | Monday, February 23, 2015 |
| APPL NO | 15/120087 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/68 (20130101) C12Q 1/6883 (20130101) C12Q 2600/16 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 40/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10878964 | Dassau et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eyal Dassau (Acton, Massachusetts); Alejandro J. Laguna Sanz (Cambridge, Massachusetts); Francis J. Doyle, III (Chestnut Hill, Massachusetts) |
| ABSTRACT | Presented herein are methods, and devices of adaptively tuning a zone based Model Predictive Control (MPC) controller, using at least one processor, which include determining, residuals based on prediction models storing, in a memory, the determined residuals, calculating a trust index by quantifying uncertainty of the prediction models using the stored residuals and tuning the MPC controller, in real time based on the calculated value of the trust index. |
| FILED | Thursday, January 12, 2017 |
| APPL NO | 16/069865 |
| ART UNIT | 2117 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/172 (20130101) A61M 2205/50 (20130101) A61M 2205/52 (20130101) A61M 2230/201 (20130101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/30 (20180101) G16H 50/50 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879983 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yunfei Ma (Santa Clara, California); Zhihong Luo (Berkeley, California); Christoph Steiger (Berlin, Germany); Carlo Giovanni Traverso (Newton, Massachusetts); Fadel Adib (Cambridge, Massachusetts) |
| ABSTRACT | Multiple antennas of a beamformer may simultaneously transmit wireless signals at different frequencies. The signals may comprise synchronized, identical wireless commands, each at a different carrier frequency. The transmitted signals may constructively and destructively interfere with each other at a receiver antenna, to form a beat signal. When the transmitted signals constructively interfere, the beat signal may cause a voltage in the receiver to exceed a threshold voltage. The threshold voltage may be a minimum voltage at which a device, which is operatively connected to the receiver antenna, is able to perform energy harvesting or wireless communication. The beamformer may operate under blind channel conditions, because the transmitted frequencies may be selected in such a way as to maximize peak power delivered under all possible channel conditions. The beamformer may deliver wireless power to a sensor or actuator that is located deep inside bodily tissue. |
| FILED | Sunday, May 17, 2020 |
| APPL NO | 16/876068 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10217 (20130101) Transmission H04B 7/0617 (20130101) Original (OR) Class H04B 13/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10880330 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | XiaoFeng Wang (Bloomington, Indiana); Kan Yuan (Bloomington, Indiana); Xiaojing Liao (Atlanta, Georgia); Raheem A. Beyah (Atlanta, Georgia) |
| ABSTRACT | System and method for detecting an infected website are disclosed. A semantic finder receives top-level domains and identifies keywords of the top-level domains representing a predetermined semantics. The keywords are compared with irrelevant bad terms to find at least one irrelevant term. An inconsistency searcher searches the top-level domains and detects at least one fully-qualified domain name carrying the at least one irrelevant term. A context analyzer evaluates context information associated with the irrelevant term, identifies at least one frequently-used term identified in the context information, and determines whether the at least one frequently-used term is unrelated to a generic content of the at least one fully-qualified domain name An irrelevant bad term collector extracts the at least one frequently-used term unrelated to the generic content and adds the extracted frequently-used term to an irrelevant bad term list for detecting the infected website. |
| FILED | Friday, May 18, 2018 |
| APPL NO | 15/983093 |
| ART UNIT | 2419 — Recording and Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9535 (20190101) G06F 21/566 (20130101) G06F 40/30 (20200101) G06F 40/205 (20200101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1483 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 10874610 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northwestern University (Evanston, Illinois); Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois); Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Huiping Liu (Chicago, Illinois); Erika K. Ramos (Chicago, Illinois); Nurmaa K. Dashzeveg (Chicago, Illinois); Golam Kibria (Chicago, Illinois) |
| ABSTRACT | This invention is related to use of exosomes for biomarker analysis for early detecting and characterizing of disease progression of cancer. Further, the invention provides bioengineered exosomes for use in methods of targeting and treating cancer. |
| FILED | Thursday, October 19, 2017 |
| APPL NO | 15/788709 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) Original (OR) Class A61K 9/1277 (20130101) A61K 31/7105 (20130101) A61K 38/00 (20130101) Peptides C07K 14/70503 (20130101) C07K 14/70596 (20130101) C07K 2319/03 (20130101) C07K 2319/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57415 (20130101) G01N 33/57484 (20130101) G01N 33/57488 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874683 | Painter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | George R. Painter (Atlanta, Georgia); David B. Guthrie (Avondale Estates, Georgia); Gregory R. Bluemling (Decatur, Georgia); Michael R. Natchus (Alpharetta, Georgia) |
| ABSTRACT | This disclosure relates to certain N4-hydroxycytidine derivatives, compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of a Zika virus infection. |
| FILED | Friday, March 10, 2017 |
| APPL NO | 16/083177 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/008 (20130101) A61K 31/7068 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/10 (20130101) C07H 19/067 (20130101) Technologies for Adaptation to Climate Change Y02A 50/391 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874720 | Siegel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Justin Siegel (Seattle, Washington); David Baker (Seattle, Washington); Sydney Rin Anna Gordon (Seattle, Washington); Ingrid Swanson Pultz (Seattle, Washington); Elizabeth Joy Stanley (Bothell, Washington); Sarah Jane Wolf (Camas, Washington) |
| ABSTRACT | Disclosed herein are compositions and methods for treating celiac sprue. |
| FILED | Wednesday, November 28, 2018 |
| APPL NO | 16/203109 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/48 (20130101) A61K 38/482 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Enzymes C12Y 304/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874742 | Kaplan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tufts University (Medford, Massachusetts) |
| ASSIGNEE(S) | Tufts University (Medford, Massachusetts) |
| INVENTOR(S) | David L. Kaplan (Concord, Massachusetts); Fiorenzo G. Omenetto (Lexington, Massachusetts); Joseph E. Brown (Somerville, Massachusetts); Rodrigo R. Jose (Medford, Massachusetts) |
| ABSTRACT | The present application relates to silk fibroin-based materials, methods for making and using the same. Provided materials exhibit shape memory characteristics while showing comparable or better volumetric swelling, biocompatibility and/or degradability when compared to current memory polymers derived from either natural or synthetic materials. |
| FILED | Friday, March 11, 2016 |
| APPL NO | 15/555225 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 2017/00867 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 47/26 (20130101) A61K 47/42 (20130101) Original (OR) Class Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/146 (20130101) A61L 2400/16 (20130101) Peptides C07K 14/43518 (20130101) C07K 14/43586 (20130101) Derivatives of Natural Macromolecular Compounds C08H 1/00 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/0085 (20130101) C08J 2389/00 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 4/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875026 | Ririe et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BIOFIRE DEFENSE, LLC (Salt Lake City, Utah) |
| ASSIGNEE(S) | BioFire Defense, LLC (Salt Lake City, Utah) |
| INVENTOR(S) | Kirk Max Ririe (Salt Lake City, Utah); David E. Jones (Layton, Utah); Christopher Paul Pasko (Salt Lake City, Utah); Anson Cole Chamberlain (American Fork, Utah); Derek David (Salt Lake City, Utah); Aaron Wernerehl (Salt Lake City, Utah); Jonathan Allen Bruns (Salt Lake City, Utah) |
| ABSTRACT | Instruments, methods, and kits are disclosed for performing fast thermocycling. |
| FILED | Tuesday, February 21, 2017 |
| APPL NO | 16/078637 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 7/525 (20130101) Original (OR) Class B01L 2200/0647 (20130101) B01L 2300/18 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2300/0867 (20130101) B01L 2300/1816 (20130101) B01L 2300/1822 (20130101) B01L 2300/1827 (20130101) B01L 2300/1861 (20130101) B01L 2400/0481 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/686 (20130101) C12Q 2527/101 (20130101) C12Q 2537/143 (20130101) C12Q 2537/149 (20130101) C12Q 2561/113 (20130101) C12Q 2563/107 (20130101) C12Q 2563/143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875197 | Lynn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Other Lab, LLC (San Francisco, California) |
| ASSIGNEE(S) | OTHER LAB, LLC (San Francisco, California) |
| INVENTOR(S) | Peter S. Lynn (Oakland, California); Saul Griffith (San Francisco, California); Kevin Albert (San Francisco, California) |
| ABSTRACT | A robotic actuator comprises a mass manufactured bellows, wherein the mass manufactured bellows allows a volume change by localized bending, and wherein the mass manufactured bellows is formed from a material that has a higher strength in at least two axes relative to at most one other axis, and an end effector, wherein the end effector is coupled to the manufactured bellows. |
| FILED | Wednesday, October 25, 2017 |
| APPL NO | 15/793591 |
| ART UNIT | 3666 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/00 (20130101) B25J 9/142 (20130101) B25J 18/06 (20130101) Original (OR) Class Spring, Weight, Inertia or Like Motors; Mechanical-power Producing Devices or Mechanisms, Not Otherwise Provided for or Using Energy Sources Not Otherwise Provided for F03G 6/02 (20130101) Pistons; Cylinders; Sealings F16J 3/04 (20130101) Solar Heat Collectors; Solar Heat Systems F24S 23/74 (20180501) F24S 30/48 (20180501) F24S 30/425 (20180501) F24S 30/428 (20180501) F24S 30/452 (20180501) F24S 50/00 (20180501) F24S 50/20 (20180501) F24S 2030/115 (20180501) F24S 2050/25 (20180501) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/32 (20141201) H02S 40/00 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/40 (20130101) Y02E 10/46 (20130101) Y02E 10/47 (20130101) Technical Subjects Covered by Former USPC Cross-reference Art Collections [XRACs] and Digests Y10S 901/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875639 | Crocco |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | John P. Crocco (Newport News, Virginia) |
| ABSTRACT | A biplaner rotor blade has an upper airfoil section connected to a lower airfoil section such that the upper airfoil and lower airfoil are rotated in separate planes—an upper plane and a lower plane. The upper airfoil has a root end attached to a hub at an upper location of the hub and the lower airfoil has a root end attached to the hub at a lower location of the hub. The upper airfoil converges with the lower airfoil to form a blade tip end at the outermost portion of the blade, thus generating lift along two geometric planes. |
| FILED | Tuesday, February 19, 2019 |
| APPL NO | 16/279595 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/463 (20130101) B64C 27/467 (20130101) B64C 27/473 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875691 | Sickenberger et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Army Edgewood Chemical Biological Center (APG, Maryland) |
| ASSIGNEE(S) | The United States of America As Represented by The Secretary Of The Army (Washington, District of Columbia) |
| INVENTOR(S) | David W Sickenberger (Bel Air, Maryland); Clarence D. Brown (Havre de Grace, Maryland) |
| ABSTRACT | A new and improved cable tie includes a core cable tie having a multi-slot head and a set of attachments that are not integrally formed with the core cable tie. A user can combine one or more attachments with a core cable tie to form a cable tie assembly. As such, a core cable tie can be modified with one or more attachments that are specific to a desired capability or configuration. This results in improved strength and cost savings in that the same core cable tie can be used for multiple applications. The user only adds attachments, such as finger or hand pulls, based on the needs of a specific situation. |
| FILED | Monday, August 20, 2018 |
| APPL NO | 16/105130 |
| ART UNIT | 3677 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 63/18 (20130101) B65D 63/1063 (20130101) Original (OR) Class B65D 2563/101 (20130101) B65D 2563/108 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875784 | Evans et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Dean R. Evans (Beavercreek, Ohio); Yuri Barnakov (Nashville, Tennessee); Ighodalo U. Idehenre (Tipp City, Ohio); Sergey A. Basun (Beavercreek, Ohio) |
| ABSTRACT | A method for synthesizing ferroelectric nanoparticles comprises introducing solutions of Ba(NO3)2 (1 mmol) in 5 ml of deionized water, NaOH (12.5 mmol) in 5 ml of deionized water, Ti(IV) n-butoxide (1 mmol) in 5 ml of 1-butanol, 2.5 ml of oleic acid, and 5 ml of 1-butanol into a Teflon-lined autoclave vessel; heating the vessel to 135° C. for 18 h, resulting in barium titanate nanoparticles; and ball-milling the barium titanate nanoparticles in a solution of oleic acid and heptane to create a colloidal suspension of nanoparticles. The weight ratio of barium titanate:oleic acid:heptane is 1:1:20. The ball-milling step may further comprise introducing a slurry comprising 0.1 g of synthesized BaTiO3 nanocubes, 0.1 g of oleic acid, and 15 mL of heptane into a ball-mill crucible filled with 2 mm ZrO2 balls; subjecting the slurry to rotation at 500 rpm for 5 hours; converting the resulting nanoparticle suspension to a powder using anhydrous ethanol with sequential washing/drying at ambient temperature. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/431774 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 23/006 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/64 (20130101) C01P 2006/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875793 | Parkey et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lynntech, Inc. (College Station, Texas) |
| ASSIGNEE(S) | Lynntech, Inc. (College Station, Texas) |
| INVENTOR(S) | Jeffrey S. Parkey (College Station, Texas); Justin McIntire (Bryan, Texas); Carlos Salinas (Bryan, Texas) |
| ABSTRACT | The present invention includes a method including providing an anode and a cathode; providing a desalination device operably coupled to establish an electrical potential between the anode and the cathode when the desalination device is operating; providing water containing dissolved solids; thereby establishing the electrical potential; reducing a salinity of the water by supplying the water to the desalination device; and generating electrical power by reducing the salinity of the water. |
| FILED | Friday, February 22, 2019 |
| APPL NO | 16/283286 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4695 (20130101) Original (OR) Class C02F 2103/08 (20130101) C02F 2201/4611 (20130101) C02F 2201/46115 (20130101) C02F 2303/10 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) H01M 8/227 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875812 | Haven et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SAINT-GOBAIN CERAMICS and PLASTICS, INC. (Worcester, Massachusetts) |
| ASSIGNEE(S) | SAINT-GOBAIN CERAMICS and PLASTICS, INC. (Worcester, Massachusetts) |
| INVENTOR(S) | Drew T. Haven (Milford, New Hampshire); Steven A. Zanella (Dublin, New Hampshire); William J. Drouin (Brookline, New Hampshire) |
| ABSTRACT | A ceramic product includes a transparent ceramic panel having a non-planar geometry including a bend having a slippage plane, an increased haze, a non-uniform thickness, or a combination thereof. A method includes providing a transparent ceramic panel, heating the panel, bending the panel to conform to a non-planar geometry. |
| FILED | Friday, October 14, 2016 |
| APPL NO | 15/294375 |
| ART UNIT | 1781 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 11/005 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 7/021 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/10 (20130101) Original (OR) Class C04B 35/622 (20130101) C04B 2235/656 (20130101) C04B 2235/3217 (20130101) C04B 2235/9653 (20130101) Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 15/34 (20130101) C30B 29/20 (20130101) C30B 29/26 (20130101) C30B 29/38 (20130101) C30B 33/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875813 | Garcia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Northrop Grumman Innovation Systems, Inc. (Plymouth, Minnesota) |
| ASSIGNEE(S) | Northrop Grumman Innovation Systems, Inc. (Plymouth, Minnesota) |
| INVENTOR(S) | Benjamin W. C. Garcia (Tremonton, Utah); David R. Nelson (Logan, Utah) |
| ABSTRACT | A preceramic resin formulation comprising a polycarbosilane preceramic polymer, an organically modified silicon dioxide preceramic polymer, and, optionally, at least one filler. The preceramic resin formulation is formulated to exhibit a viscosity of from about 1,000 cP at about 25° C. to about 5,000 cP at a temperature of about 25° C. The at least one filler comprises first particles having an average mean diameter of less than about 1.0 μm and second particles having an average mean diameter of from about 1.5 μm to about 5 μm. Impregnated fibers comprising the preceramic resin formulation are also disclosed, as is a composite material comprising a reaction product of the polycarbosilane preceramic polymer, organically modified silicon dioxide preceramic polymer, and the at least one filler. Methods of forming a ceramic matrix composite are also disclosed. |
| FILED | Tuesday, November 21, 2017 |
| APPL NO | 15/819658 |
| ART UNIT | 1796 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/00 (20130101) B64C 1/12 (20130101) B64C 1/066 (20130101) B64C 3/26 (20130101) B64C 11/20 (20130101) B64C 2001/0072 (20130101) B64C 2027/4733 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/58 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/80 (20130101) C04B 35/82 (20130101) C04B 35/571 (20130101) Original (OR) Class C04B 35/806 (20130101) C04B 35/62863 (20130101) C04B 35/62868 (20130101) C04B 2235/386 (20130101) C04B 2235/483 (20130101) C04B 2235/3206 (20130101) C04B 2235/3217 (20130101) C04B 2235/3244 (20130101) C04B 2235/3248 (20130101) C04B 2235/3418 (20130101) C04B 2235/3804 (20130101) C04B 2235/3813 (20130101) C04B 2235/3826 (20130101) C04B 2235/3839 (20130101) C04B 2235/3843 (20130101) C04B 2235/3847 (20130101) C04B 2235/3865 (20130101) C04B 2235/3873 (20130101) C04B 2235/5212 (20130101) C04B 2235/5248 (20130101) C04B 2235/5436 (20130101) C04B 2235/5445 (20130101) C04B 2235/5472 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/282 (20130101) F01D 25/005 (20130101) Jet-propulsion Plants F02K 9/08 (20130101) F02K 9/346 (20130101) F02K 9/974 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/20 (20130101) F05D 2300/6033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875907 | Lai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. (Bronx, New York); THE GOVERNING COUNCEL OF THE UNIVERSITY OF TORONTO (Toronto, Canada); THE GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE ARMY (Fort Detrick, Maryland) |
| ASSIGNEE(S) | Albert Einstein College of Medicine (Bronx, New York); The Governing Council of the University of Toronto (Toronto, Canada); The Government of the United States as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| INVENTOR(S) | Jonathan R. Lai (Dobbs Ferry, New York); Jayne F. Koellhoffer (New York, New York); Julia Frei (Bronx, New York); Kartik Chandran (Brooklyn, New York); Sachdev Sidhu (Toronto, Canada); Gang Chen (Toronto, Canada); John M. Dye (Frederick, Maryland); Samantha Zak (Frederick, Maryland) |
| ABSTRACT | The present invention addresses a need for antibodies useful for filovirus infections. |
| FILED | Tuesday, September 18, 2018 |
| APPL NO | 16/134041 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 16/24 (20130101) C07K 2317/24 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876058 | Ruiz |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Oscar N. Ruiz (Bellbrook, Ohio) |
| ABSTRACT | A method for preventing biodeterioration of fuel. The method reduces the microbial growth in fuel by administering an antimicrobial peptide (or efflux pump inhibitor) to a fuel phase of the fuel, an aqueous phase of the fuel, or both, which disrupts the cellular membrane (or the efflux pumps thereof) of microbes comprising the growth. |
| FILED | Friday, August 30, 2019 |
| APPL NO | 16/556901 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/14 (20130101) Original (OR) Class C10L 1/238 (20130101) C10L 2230/083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876059 | Ruiz |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Oscar N. Ruiz (Bellbrook, Ohio) |
| ABSTRACT | A method for preventing biodeterioration of fuel. The method reduces the microbial growth in fuel by administering an antimicrobial peptide (or efflux pump inhibitor) to a fuel phase of the fuel, an aqueous phase of the fuel, or both, which disrupts the cellular membrane (or the efflux pumps thereof) of microbes comprising the growth. |
| FILED | Friday, August 30, 2019 |
| APPL NO | 16/557014 |
| ART UNIT | 1771 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/14 (20130101) Original (OR) Class C10L 1/238 (20130101) C10L 2230/083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876088 | Griffith et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Linda Griffith (Cambridge, Massachusetts); David Trumper (Plaistow, New Hampshire); Collin Edington (Cambridge, Massachusetts); Gaurav Rohatgi (Boston, Massachusetts); Duncan Freake (Boston, Massachusetts); Luis Soenksen (Boston, Massachusetts); Mohan Brij Bhushan (Cambridge, Massachusetts) |
| ABSTRACT | Fluidic multiwell bioreactors are provided as a microphysiological platform for in vitro investigation of multi-organ crosstalks for an extended period of time of at least weeks and months. The disclosed platform is featured with one or more improvements over existing bioreactors, including on-board pumping for pneumatically driven fluid flow, a redesigned spillway for self-leveling from source to sink, a non-contact built-in fluid level sensing device, precise control on fluid flow profile and partitioning, and facile reconfigurations such as daisy chaining and multilayer stacking. The platform supports the culture of multiple organs in a microphysiological, interacted systems, suitable for a wide range of biomedical applications including systemic toxicity studies and physiology-based pharmacokinetic and pharmacodynamic predictions. A process to fabricate the disclosed bioreactors is also provided. |
| FILED | Monday, February 06, 2017 |
| APPL NO | 15/425858 |
| ART UNIT | 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 3/502738 (20130101) B01L 2200/0621 (20130101) B01L 2300/0829 (20130101) B01L 2300/0887 (20130101) B01L 2400/086 (20130101) B01L 2400/0406 (20130101) B01L 2400/0457 (20130101) B01L 2400/0487 (20130101) B01L 2400/0655 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) Original (OR) Class C12M 25/14 (20130101) C12M 29/10 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 19/006 (20130101) F04B 23/04 (20130101) F04B 23/06 (20130101) F04B 43/12 (20130101) F04B 43/043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876202 | Verbeck, IV et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of North Texas (Denton, Texas) |
| ASSIGNEE(S) | University of North Texas (Denton, Texas) |
| INVENTOR(S) | Guido Fridolin Verbeck, IV (Lewisville, Texas); Stephen Davila (Odessa, Texas) |
| ABSTRACT | A soft-landing (SL) instrument for depositing ions onto substrates using a laser ablation source is described herein. The instrument of the instant invention is designed with a custom drift tube and a split-ring ion optic for the isolation of selected ions and is capable of operating at atmospheric pressure. The drift tube allows for the separation and thermalization of ions formed after laser ablation through collisions with an inert bath gas that allow the ions to be landed at energies below 1 eV onto substrates. The split-ring ion optic is capable of directing ions toward the detector or a landing substrate for selected components. |
| FILED | Friday, August 25, 2017 |
| APPL NO | 15/686864 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 2201/112 (20130101) Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/04 (20130101) C23C 14/12 (20130101) C23C 14/14 (20130101) C23C 14/28 (20130101) C23C 14/52 (20130101) C23C 14/54 (20130101) C23C 14/221 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 37/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876411 | Ramirez |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | United Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Loubriel Ramirez (San Antonio, Puerto Rico) |
| ABSTRACT | A turbine section includes a pair of adjacent turbine airfoils and an endwall extending between the airfoils. The endwall includes a first feature spanning approximately twenty percent pitch and having a first depression with a first maximum depression located between twenty percent and sixty percent of an axial chord length of the first airfoil, a second feature adjacent the first feature with the second feature spanning approximately forty percent pitch and having a first peak with a maximum height located between twenty percent and sixty percent of the axial chord length of the first airfoil, and a third feature adjacent the second feature and first side of the second airfoil with the third feature spanning approximately forty percent pitch and having a second depression with a second maximum depression located between thirty percent and sixty percent of an axial chord length of the second airfoil. |
| FILED | Monday, April 08, 2019 |
| APPL NO | 16/378161 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/143 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/73 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876472 | Roychoudhury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| ASSIGNEE(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| INVENTOR(S) | Subir Roychoudhury (Madison, Connecticut); Richard Mastanduno (Milford, Connecticut); David Lang Spence (Beacon Falls, Connecticut); Bruce Crowder (Hamden, Connecticut); Curtis Morgan (Southington, Connecticut) |
| ABSTRACT | A spark-ignited (SI) internal combustion (IC) engine designed to operate on high octane fuels, such as gasoline, is reconfigured to operate on low octane fuels including logistically preferred distillate fuels, such as diesel or JP-8. Design modifications involve coupling a fuel reformer module to the internal combustion engine. Auxiliary components include a system control module, a heat exchange module, a bypass valve to facilitate start-up, and/or a throttle body to control a reformate-oxidizer mixture fed to the engine. Small portable generators having 0.3-3.0 kWe power output are disclosed based upon the modified SI-IC engine design. |
| FILED | Friday, June 22, 2018 |
| APPL NO | 16/015305 |
| ART UNIT | 3747 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Internal-combustion Piston Engines; Combustion Engines in General F02B 51/02 (20130101) F02B 63/04 (20130101) F02B 69/02 (20130101) Original (OR) Class Controlling Combustion Engines F02D 9/02 (20130101) F02D 41/0025 (20130101) Hot Gas or Combustion-product Positive-displacement Engine Plants; Use of Waste Heat of Combustion Engines; Not Otherwise Provided for F02G 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876608 | Kernbaum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI INTERNATIONAL (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Alexander Steele Kernbaum (Sunnyvale, California); Curt Salisbury (San Ramon, California) |
| ABSTRACT | An apparatus includes a first ring having an open annular space and a variable-width groove disposed on an interior peripheral surface of the first ring; a second ring rotatable within the open annular space of the first ring, where the second ring has a respective variable-width groove disposed on an exterior peripheral surface of the second ring; and a plurality of rollers disposed between, and configured to roll on, the interior peripheral surface of the first ring and the exterior peripheral surface of the second ring and rotatable therebetween. |
| FILED | Thursday, April 23, 2020 |
| APPL NO | 16/856848 |
| ART UNIT | 3659 — Material and Article Handling |
| CURRENT CPC | Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 33/32 (20130101) Gearing F16H 1/28 (20130101) F16H 13/06 (20130101) F16H 13/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876824 | Rastegar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Omnitek Partners LLC (Ronkonkoma, New York) |
| ASSIGNEE(S) | OMNITEK PARTNERS LLC (Ronkonkoma, New York) |
| INVENTOR(S) | Jahangir S Rastegar (Stony Brook, New York); Jacques Fischer (Sound Beach, New York) |
| ABSTRACT | A device for generating power in a gravity dropped munition. The device including: a drum; a cable wound around a drum; a generator for producing electrical energy; a spring configured to convert rotation of the drum to energy as the cable is unwound from the drum; and an intermediate member selectively engaging the drum to the generator; wherein the intermediate member is disengaged from the drum when the cable is being unwound from the drum and the intermediate member is engaged with the generator when the cable is released from the drum to produce power from the generator. |
| FILED | Monday, November 25, 2019 |
| APPL NO | 16/695058 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 25/00 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 11/008 (20130101) Original (OR) Class F42C 14/06 (20130101) F42C 15/005 (20130101) F42C 15/40 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876840 | Feke |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Charles Stark Draper Laboratory, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Gilbert D. Feke (Windham, New Hampshire) |
| ABSTRACT | A passive ring interferometer sensor includes an electromagnetic ring path configured to receive a pair of electromagnetic waves from an electromagnetic radiation source and to direct the waves to be counter-propagating within the ring path toward respective ends of the path. A combination junction receives the waves from the respective ends and combines the waves to be co-propagating within a coupling path. Polarization elements are configured to set the waves to be mutually co-polarized within the electromagnetic ring path and to be mutually cross-polarized within the coupling path. A detector is configured to receive the mutually cross-polarized waves from the coupling path and to detect second-order coherence. Embodiments can sense rotation rate as fiber-optic gyroscopes or serve as other types of sensors such as gravitational wave sensors. Embodiments may have greatly increased unambiguous range and decreased sensitivity to any centroid wavelength shift. |
| FILED | Friday, April 12, 2019 |
| APPL NO | 16/382758 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 19/721 (20130101) G01C 19/727 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876891 | Mitchell |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wavefront Research, Inc. (Northampton, Pennsylvania) |
| ASSIGNEE(S) | Wavefront Research, Inc. (Northhampton, Pennsylvania) |
| INVENTOR(S) | Thomas A. Mitchell (Northampton, Pennsylvania) |
| ABSTRACT | An imaging optical system including a plurality of imaging optical sub-systems, each having at least one optical element and receiving light from a source, and a plurality of spectrometer optical sub-systems, each spectrometer optical sub-system receiving light from at least one of the imaging optical sub-systems, each imaging optical sub-system and spectrometer optical sub-system combination having a spatial distortion characteristic, each spatial distortion characteristic having a predetermined relationship to the other spatial distortion characteristics. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/587502 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/02 (20130101) G01J 3/18 (20130101) G01J 3/28 (20130101) Original (OR) Class G01J 3/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876900 | Gord et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James R. Gord (Beavercreek, Ohio); Sukesh Roy (Dayton, Ohio); Paul S. Hsu (Dayton, Ohio); Naibo Jiang (Dayton, Ohio); Mikhail N. Slipchenko (West Lafayette, Indiana) |
| ABSTRACT | Systems and methods for measuring temperature in an environment by creating a first beam having an energy of about 50 mJ/pulse, and a pulse duration of about 100 ps. A second beam is also created, having an energy of about 2.3 mJ/pulse, and a pulse duration of about 58 ps. The first beam and the second beam are directed into a probe region, thereby expressing an optical output. Properties of the optical output are measured at a sampling rate of at least about 100 kHz, and temperature measurements are derived from the measured properties of the optical output. Such systems and methods can be used to measure temperature in environments exhibiting highly turbulent and transient flow dynamics. |
| FILED | Thursday, August 02, 2018 |
| APPL NO | 16/052763 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/4412 (20130101) G01J 5/0014 (20130101) G01J 5/601 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/1024 (20130101) H01S 3/1666 (20130101) H01S 3/10007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876942 | Wikswo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Philip C. Samson (Nashville, Tennessee) |
| ABSTRACT | A system for applying and measuring tensions of a plurality of bio-object constructs includes a base; and a flexible body disposed on the base, wherein the flexible body defines a plurality of construct holes for accommodating the plurality of bio-object constructs, such that when the flexible body is bent, the bending of the flexible body causes tensions to be applied to the plurality of bio-object constructs, thereby causing displacements of the plurality of bio-object constructs. |
| FILED | Wednesday, July 22, 2020 |
| APPL NO | 16/935457 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 5/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/20 (20130101) Original (OR) Class G01N 2203/028 (20130101) G01N 2203/0089 (20130101) G01N 2203/0094 (20130101) G01N 2203/0647 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0004 (20130101) G02B 21/08 (20130101) G02B 21/26 (20130101) G02B 21/365 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876971 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Chenxiang Lin (Cambridge, Massachusetts); Chao Li (Boston, Massachusetts); William M. Shih (Cambridge, Massachusetts); Peng Yin (Brookline, Massachusetts); Ralf Jungmann (Munich, Germany) |
| ABSTRACT | Provided herein are, inter alia, barcode probes comprised of transiently or stably fluorescently labeled nucleic acid nanostructures that are fully addressable and able to be read using standard fluorescent microscope and methods of use thereof including methods of use as detectable labels for probes. |
| FILED | Thursday, June 14, 2018 |
| APPL NO | 16/008719 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 2563/107 (20130101) C12Q 2563/157 (20130101) C12Q 2563/185 (20130101) C12Q 2565/102 (20130101) C12Q 2565/601 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877003 | Kessler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Metis Design Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Metis Design Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Seth S. Kessler (Newton, Massachusetts); Michael Borgen (Wilmington, Massachusetts); Christopher T. Dunn (Salem, Massachusetts) |
| ABSTRACT | Exemplary embodiments are directed to instrumented fasteners and associated damage detection systems for detecting damage in an assembled structure secured together by at least one instrumented fastener. The instrumented fastener forms a transducer assembly for detecting damage in the assembled structure. The fastener can include a cavity disposed at one end of the fastener. The transducer assembly includes an electromechanical unit at least partially inserted into and mechanically coupled within the cavity of the fastener. The electromechanical unit can include a piezoelectric element. |
| FILED | Wednesday, March 06, 2019 |
| APPL NO | 16/294366 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 29/04 (20130101) G01N 29/2437 (20130101) Original (OR) Class G01N 2291/2691 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877011 | Cummings et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Nexceris, LLC (Lewis Center, Ohio) |
| ASSIGNEE(S) | NEXCERIS, LLC (Lewis Center, Ohio) |
| INVENTOR(S) | Stephen Randall Cummings (Worthington, Ohio); Scott Lawrence Swartz (Columbus, Ohio); Nicholas Brannigan Frank (Columbus, Ohio); William John Dawson (Dublin, Ohio); Davion Matthew Hill (Grandview Heights, Ohio); Benjamin H. Gully (Oslo, Norway) |
| ABSTRACT | Systems and methods are described herein for monitoring a gas source for a gas analyte. The gas source can be monitored for release of the gas analyte, for example, during a given gas source state. A sensor signal can be generated characterizing an amount of the gas analyte being released by the gas source. The gas sensor signal can be evaluated relative to a threshold. An alert signal can be generated based on a result of the comparison to provide a warning that unwanted and/or hazardous amounts of gas is being released by the gas source. |
| FILED | Thursday, June 29, 2017 |
| APPL NO | 15/637381 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/04 (20130101) G01N 33/0063 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/4228 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877074 | Bulsara et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adi R. Bulsara (San Diego, California); Nigel Stocks (Coventry, United Kingdom); Alexander Nikitin (Coventry, United Kingdom) |
| ABSTRACT | A system and method include a non-linear dynamic sensor, such as a magnetic field sensor, having an oscillator with a dynamic response that passes through a critical point beyond which the oscillator responds in an oscillatory regime. A processor operatively connected to the non-linear dynamic sensor is configured to, based upon an input signal x received by the non-linear dynamic sensor, adaptively self-tune the non-linear dynamic sensor to a dynamic range within the oscillatory regime adjacent to the critical point such that the input signal x spans the entire dynamic range. An array of such sensors includes a global feedback capability to mitigate coupling losses. |
| FILED | Monday, September 18, 2017 |
| APPL NO | 15/707512 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 15/202 (20130101) Original (OR) Class G01R 15/205 (20130101) G01R 15/207 (20130101) G01R 33/07 (20130101) Generation of Oscillations, Directly or by Frequency-changing, by Circuits Employing Active Elements Which Operate in a Non-switching Manner; Generation of Noise by Such Circuits H03B 5/326 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877110 | Finkel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | 06;The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia); 02;Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Peter Finkel (Baltimore, Maryland); Steven P. Bennett (Alexandria, Virginia); Margo Staruch (Alexandria, Virginia); Konrad Bussmann (Alexandria, Virginia); Jeffrey W. Baldwin (Fairfax, Virginia); Bernard R. Matis (Alexandria, Virginia); Ronald Lacomb (West Greenwich, Rhode Island); William Zappone (West Greenwich, Rhode Island); Julie Lacomb (West Greenwich, Rhode Island); Meredith Metzler (Havertown, Pennsylvania); Norman Gottron (Pittsburgh, Pennsylvania) |
| ABSTRACT | A high-sensitivity and ultra-low power consumption magnetic sensor using a magnetoelectric (ME) composite comprising of magnetostrictive and piezoelectric layers. This sensor exploits the magnetically driven resonance shift of a free-standing magnetoelectric micro-beam resonator. Also disclosed is the related method for making the magnetic sensor. |
| FILED | Tuesday, March 13, 2018 |
| APPL NO | 15/919529 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 25/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/093 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 41/29 (20130101) H01L 41/47 (20130101) H01L 41/1132 (20130101) H01L 43/08 (20130101) H01L 43/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877125 | Ward |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Benjamin G. Ward (Colorado Springs, Colorado) |
| ABSTRACT | In accordance with various embodiments of the disclosed subject matter, a system, apparatus and method is configured to receive/process radio frequency emanations of a potentially threatening drone to generate therefrom a human-recognizable audio signal characteristic of the drone (i.e., a “voice” of the drone) so that a warfighter may be alerted to the activity of the drone and respond accordingly. |
| FILED | Wednesday, June 05, 2019 |
| APPL NO | 16/432010 |
| ART UNIT | 2685 — Selective Communication |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 3/046 (20130101) Original (OR) Class G01S 19/42 (20130101) Antennas, i.e Radio Aerials H01Q 3/02 (20130101) H01Q 15/14 (20130101) Secret Communication; Jamming of Communication H04K 3/92 (20130101) Wireless Communication Networks H04W 4/40 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877282 | Williams et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Allie Williams (Panama City Beach, Florida); Richard Manley (Panama City Beach, Florida); Brian Wentworth (Panama City, Florida); Dennis Gallagher (Lynn Haven, Florida); William Hughes (Lynn Haven, Florida) |
| ABSTRACT | A head up display system includes first and second optical waveguides. A bracket holds the optical waveguides in a spaced-apart fixed relationship to one another such that their optical axes are separated by a distance of 63.5-65 millimeters. The optical waveguides are angularly disposed with respect to one another to produce a binocular image whose focal plane is located out at a distance of 2-4 meters. The bracket also specifically positions the optical waveguides adjacent to a transparent face plate of a dive helmet or dive mask. |
| FILED | Friday, June 28, 2019 |
| APPL NO | 16/456813 |
| ART UNIT | 2623 — Selective Visual Display Systems |
| CURRENT CPC | Launching, Hauling-out, or Dry-docking of Vessels; Life-saving in Water; Equipment for Dwelling or Working Under Water; Means for Salvaging or Searching for Underwater Objects B63C 11/12 (20130101) B63C 2011/121 (20130101) Optical Elements, Systems, or Apparatus G02B 27/0172 (20130101) G02B 27/0176 (20130101) Original (OR) Class G02B 2027/0132 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877287 | Miller |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | David A. B. Miller (Stanford, California) |
| ABSTRACT | Universal linear components are provided. In general, a P input and Q output wave combiner is connected to a Q input and R output wave mode synthesizer via Q amplitude and/or phase modulators. The wave combiner and wave mode synthesizer are both linear, reciprocal and lossless. The wave combiner and wave mode synthesizer can be implemented using waveguide technology. This device can provide any desired linear transformation of spatial modes between its inputs and its outputs. This capability can be generalized to any linear transformation by using representation converters to convert other quantities to spatial mode patterns. The wave combiner and wave mode synthesizer are also useful separately, and can enable applications including self-adjusting mode coupling, optimal multi-mode communication, and add-drop capability in a multi-mode system. Control of the wave combiner and wave mode synthesizer can be implemented with single-variable optimizations. |
| FILED | Monday, March 11, 2019 |
| APPL NO | 16/298531 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/145 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/31 (20130101) G02F 1/0136 (20130101) G02F 2001/212 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877300 | Coolbaugh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York); Government of the United States, as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio); Morton Photonics Incorporated (West Friendship, Maryland) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York); GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Wright-Patterson AFB, Ohio); MORTON PHOTONICS INCORPORATED (West Friendship, Maryland) |
| INVENTOR(S) | Douglas Coolbaugh (Mechanicville, New York); Douglas La Tulipe (Guilderland, New York); Paul A. Morton (West Friendship, Maryland); Nicholas G. Usechak (Oakwood, Ohio) |
| ABSTRACT | There is set forth herein an integrated photonics structure having a waveguide disposed within a dielectric stack of the integrated photonics structure, wherein the integrated photonics structure further includes a field generating electrically conductive structure disposed within the dielectric stack; and a heterogenous structure attached to the integrated photonics structure, the heterogenous structure having field sensitive material that is sensitive to a field generated by the field generating electrically conductive structure. There is set forth herein a method including fabricating an integrated photonics structure, wherein the fabricating an integrated photonics structure includes fabricating a waveguide within a dielectric stack, wherein the fabricating an integrated photonics structure further includes fabricating a field generating electrically conductive structure within the dielectric stack; and attaching a heterogenous structure to the integrated photonics structure, the heterogenous structure having field sensitive material that is sensitive to a field generated by the field generating electrically conductive structure. |
| FILED | Wednesday, April 03, 2019 |
| APPL NO | 16/374341 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/12 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/035 (20130101) Original (OR) Class G02F 1/095 (20130101) G02F 1/0955 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877444 | Roach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Shane M. Roach (Helena, Montana); Michael D. Howard (Westlake Village, California); Praveen K. Pilly (West Hills, California) |
| ABSTRACT | Described is a system for biofeedback, the system including one or more processors and a memory, the memory being a non-transitory computer-readable medium having executable instructions encoded thereon, such that upon execution of the instructions, the one or more processors perform operations including using a first biometric sensor during performance of a current task, acquiring first biometric data, and producing a first biometric value by assessing the first biometric data. The one or more processors further perform operations including determining a first relevance based on a first significance of a first correlation between the first biometric value and the current task, and controlling a device based on the first relevance and the first biometric value. |
| FILED | Tuesday, April 03, 2018 |
| APPL NO | 15/944530 |
| ART UNIT | 2116 — Computer Error Control, Reliability, & Control Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/18 (20130101) A61B 5/165 (20130101) A61B 5/0205 (20130101) A61B 5/0402 (20130101) A61B 5/0482 (20130101) A61B 5/486 (20130101) A61B 5/0488 (20130101) A61B 5/0533 (20130101) A61B 5/742 (20130101) A61B 5/746 (20130101) A61B 5/0816 (20130101) A61B 5/04012 (20130101) A61B 5/6803 (20130101) A61B 5/7267 (20130101) A61B 5/7405 (20130101) A61B 5/7455 (20130101) A61B 2503/22 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/042 (20130101) Original (OR) Class G05B 13/0265 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10878033 | Ahmed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Mohamed N. Ahmed (Leesburg, Virginia); Charles E. Beller (Baltimore, Maryland); William G. Dubyak (Severna Park, Maryland); Palani Sakthi (Palatine, Illinois); Kristen M. Summers (Takoma Park, Maryland); Andeep S. Toor (Chantilly, Virginia) |
| ABSTRACT | An embodiment of the invention may include a method, computer program product and system for generating follow-up questions based on machine learning utilizing a computing device. The embodiment may include receiving an input question from a user. The embodiment may include parsing the received input question to extract input question components. Parsing utilizes natural language processing techniques. The embodiment may include executing trained question component models to predict follow-up question components. The extracted input question components are utilized as inputs to the trained question component models. The embodiment may include combining the predicted follow-up question components to generate one or more follow-up questions. The embodiment may include returning the one or more follow-up questions to the user. |
| FILED | Friday, December 01, 2017 |
| APPL NO | 15/829601 |
| ART UNIT | 2167 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9038 (20190101) G06F 16/9535 (20190101) G06F 16/90324 (20190101) Original (OR) Class G06F 16/90332 (20190101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10878260 | Jensen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| ASSIGNEE(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| INVENTOR(S) | Devin Richard Jensen (Cambridge, Massachusetts) |
| ABSTRACT | A micro-fiducial marker arrangement representing a unique ID that is readable by a camera during an imaging operation. The micro-fiducial marker includes a base substrate, a perimeter line, an orientation bar, and a plurality of bit cells. The base substrate may be a first color, while the perimeter line, the orientation bar, and the plurality of bit cells may be a color that is different from the first color. The perimeter line may be positioned on the base substrate and arranged to run along a perimeter of the base substrate. Each of said plurality of bit cells may be either the first color or the second color to represent a binary-coded datum. |
| FILED | Wednesday, October 17, 2018 |
| APPL NO | 16/162646 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1697 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 43/00 (20130101) B64D 47/08 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/1413 (20130101) G06K 9/00832 (20130101) Original (OR) Class G06K 9/4604 (20130101) G06K 19/0614 (20130101) G06K 2209/01 (20130101) G06K 2209/21 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10878281 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Yu Cheng (Ossining, New York); Sharathchandra U. Pankanti (Darien, Connecticut); Nalini K. Ratha (White Plains, New York) |
| ABSTRACT | A face clustering system for video face clustering in a video sequence, the system including an inherent supervision summarization device configured to collect group-level supervision and instance level supervision within a same chunklet based on a user input of face images for a person, a discriminative projection learning device configured to embed group constraints of the group-level supervision into a transformed space, and configured to generate an embedding space from the original image feature space, and a clustering device, in the embedding space, configured to execute pair-wise based clustering to cluster the video images into different clusters with the instance level supervision collected by the inherent supervision summarization device. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/587134 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00288 (20130101) G06K 9/00295 (20130101) G06K 9/00718 (20130101) G06K 9/6218 (20130101) Original (OR) Class G06K 9/6264 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10878706 | Saunders |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| ASSIGNEE(S) | Aurora Flight Sciences Corporation (Manassas, Virginia) |
| INVENTOR(S) | Jeffery Saunders (Manassas, Virginia) |
| ABSTRACT | The present disclosure is directed to systems and methods for trajectory and route planning including obstacle detection and avoidance for an aerial vehicle. For example, an aerial vehicle's flight control system may include a trajectory planner that may use short segments calculated using an iterative Dubins path to find a first path between a start point and an end point that does not avoid obstacles. Then the trajectory planner may use a rapidly exploring random tree algorithm that uses points along the first path as seed points to find a trajectory or route between the start point and end point that avoids known or detected obstacles. |
| FILED | Friday, October 12, 2018 |
| APPL NO | 16/158987 |
| ART UNIT | 3661 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Systems for Controlling or Regulating Non-electric Variables G05D 1/0088 (20130101) G05D 1/0202 (20130101) Traffic Control Systems G08G 5/0034 (20130101) Original (OR) Class G08G 5/045 (20130101) G08G 5/0069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10878985 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Mahendra DC (Saint Paul, Minnesota); Mahdi Jamali (Folsom, California); Andre Mkhoyan (Minneapolis, Minnesota); Danielle Hickey (State College, Pennsylvania) |
| ABSTRACT | A material may include at least one of BixSe(1-x), BixTe(1-x), or SbxTe(1-x), where x is greater than 0 and less than 1. In some examples, the material exhibits a Spin Hall Angle of greater than 3.5 at room temperature. The disclosure also describes examples of devices that include a spin-orbit torque generating layer, in which the spin-orbit torque generating layer includes at least one of BixSe(1-x), BixTe(1-x), or SbxTe(1-x), where x is greater than 0 and less than 1. In some examples, the spin-orbit torque generating layer exhibits a Spin Hall Angle of greater than 3.5 at room temperature. |
| FILED | Friday, December 08, 2017 |
| APPL NO | 15/836421 |
| ART UNIT | 2825 — Semiconductors/Memory |
| CURRENT CPC | Static Stores G11C 11/18 (20130101) G11C 11/161 (20130101) G11C 11/1675 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 10/30 (20130101) H01F 10/123 (20130101) H01F 10/329 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/04 (20130101) H01L 43/06 (20130101) H01L 43/08 (20130101) H01L 43/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879613 | Chen |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Shuguang Chen (Bel Air, Maryland) |
| ABSTRACT | Various embodiments are described that relate to patch antenna elements and parasitic feed pads. A patch antenna element can have a resistance and reactance. The resistance can be desirable while the reactance can be undesirable. To counteract the reactance, a parasitic feed pad can be placed near the patch antenna element and the parasitic feed pad produces a capacitance. The capacitance balances out the reactance to cancel out one another. When two patch antenna elements and two parasitic feed elements are employed in one antenna stack, the stack antenna can function as a dual band antenna. |
| FILED | Tuesday, April 14, 2020 |
| APPL NO | 16/847697 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 9/045 (20130101) Original (OR) Class H01Q 9/0414 (20130101) H01Q 21/08 (20130101) H01Q 21/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879617 | Rivera |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| INVENTOR(S) | David F Rivera (Westerly, Rhode Island) |
| ABSTRACT | An antenna is provided with a plurality of spaced-apart interdigital back plates covered by a slotted plate having a longitudinal slot of varying rectangular parameters. A plurality of spacers are positioned between the interdigital back plates and the slotted plate. A support stiffener connects the interdigital back plates at a trough of each back plate with three rectangular stanchions extending perpendicular from the support stiffener to attach to the slotted plate. A feed point is positioned on a central rectangular stanchion and beneath a central slot of the slotted plate. A feed cowl protects the feed point. The sizing of a slot in the slotted plate depends on an operating wavelength. |
| FILED | Wednesday, July 31, 2019 |
| APPL NO | 16/527447 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/364 (20130101) H01Q 9/06 (20130101) H01Q 13/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879671 | Deppe |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | sdPhotonics LLC (Richardson, Texas) |
| ASSIGNEE(S) | sdPhotonics LLC (Richardson, Texas) |
| INVENTOR(S) | Dennis G. Deppe (Richardson, Texas) |
| ABSTRACT | A semiconductor vertical resonant cavity light source includes an upper and lower mirror that define a vertical resonant cavity. An active region is within the cavity for light generation between the upper and lower mirror. At least one cavity spacer region is between the active region and the upper mirror or lower mirror. The cavity includes an inner mode confinement region and an outer current blocking region. An index guide in the inner mode confinement region is between the cavity spacer region and the upper or lower mirror. The index guide and outer current blocking region each include a lower and upper epitaxial material layer thereon with an epitaxial interface region in between. At least a top surface of the lower material layer includes aluminum in the interface region throughout a full area of an active part of the vertical light source. |
| FILED | Friday, August 09, 2019 |
| APPL NO | 16/537139 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/183 (20130101) H01S 5/187 (20130101) H01S 5/1833 (20130101) H01S 5/2018 (20130101) H01S 5/2059 (20130101) H01S 5/2072 (20130101) H01S 5/18308 (20130101) H01S 5/18327 (20130101) H01S 5/18333 (20130101) Original (OR) Class H01S 5/18358 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879714 | Couvillon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the Unite States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Ivan Couvillon (Lutherville, Maryland); Matthew Limpert (Bel Air, Maryland) |
| ABSTRACT | Various embodiments are described that relate to a battery. A battery, such as a battery with a common input/output terminal, can be tested. Part of this testing can include charging the battery and discharging the battery. It can be dangerous to switch out an interface between charging and discharging. Therefore, a single interface can be employed that enables the battery to be charged and discarded. With this, the battery can be charged and discharged without the danger of switching the interface. |
| FILED | Thursday, February 27, 2020 |
| APPL NO | 16/802886 |
| ART UNIT | 2859 — Printing/Measuring and Testing |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 7/0068 (20130101) Original (OR) Class H02J 7/0069 (20200101) H02J 2207/40 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879877 | Yadav |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The MITRE Corporation (McLean, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Rishi Yadav (Nashua, New Hampshire) |
| ABSTRACT | Provided herein is an implementation of a finite impulse response (FIR) filter that uses a distributed arithmetic architecture. In one or more example, a data sample with multiple bits is processed through a plurality of bit-level multiply and accumulate circuits, wherein each bit of the data sample corresponds to a bit of the data sample. The output of each bit-level multiply and accumulate circuit can then be shifted by an appropriate amount based on the bit placement of the bit of the data sample that corresponds to the bit-level multiply and accumulate circuit. After each output is shifted by the appropriate amount, the outputs can be aggregated to form a final FIR filter result. |
| FILED | Friday, September 28, 2018 |
| APPL NO | 16/146479 |
| ART UNIT | 2182 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 7/5443 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 17/06 (20130101) Original (OR) Class H03H 17/0225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879966 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland) |
| ASSIGNEE(S) | INTELLIGENT FUSION TECHNOLOGY, INC. (Germantown, Maryland) |
| INVENTOR(S) | Zhonghai Wang (Germantown, Maryland); Lun Li (Germantown, Maryland); Jingyang Lu (Germantown, Maryland); Genshe Chen (Germantown, Maryland); Weifeng Su (East Amherst, New York); Xingping Lin (Germantown, Maryland); Xingyu Xiang (Germantown, Maryland); Wenhao Xiong (Germantown, Maryland) |
| ABSTRACT | A multiple-input and multiple-output (MIMO) bolt-on device for a single-input and single-output (SISO) radio, a MIMO channel emulator for testing the MIMO bolt-on device, and a MIMO channel emulation method are provided. The MIMO bolt-on device includes: a plurality of antennas, a multi-channel receiver, a plurality of couplers, a micro-controller, and a switch device. The multi-channel receiver includes a plurality of channels for signal transmission. Each coupler is configured to couple the multi-channel receiver with one of the plurality of antennas. The micro-controller is coupled to the multi-channel receiver to compare signals from the plurality of channels, thereby identifying a channel with a highest signal-to-noise (SNR) among the plurality of channels. The switch device is coupled to the micro-controller and configured to select an antenna corresponding to the channel with the highest SNR among the plurality of antennas for a connection between a selected antenna and the SISO radio. |
| FILED | Wednesday, August 12, 2020 |
| APPL NO | 16/991583 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission H04B 7/0413 (20130101) Original (OR) Class H04B 17/336 (20150115) H04B 17/3912 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10880028 | Knebel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Erik Sean Knebel (Washington, District of Columbia); Murali Tummala (Monterey, California); John C. McEachen (Carmel, California) |
| ABSTRACT | A system and method for clock-skew-based covert communication in which a message formed of message bits is mapped to corresponding symbols having predetermined clock skew values. For each corresponding symbol, an offset value is calculated and added to each timestamp in a predetermined quantity of outgoing TCP segments to generated altered TCP segments, such that an artificial clock skew is induced as measured by a receiver. A clock skew value is determined from each predetermined quantity of TCP segments and mapped to corresponding symbol. The symbols are then mapped to corresponding message bits, and the message is determined from the bits. In this way a message can be sent from a transmitter to a receiver in a way that is covert during transmission and deciphered at the receiver. |
| FILED | Thursday, November 07, 2019 |
| APPL NO | 16/676599 |
| ART UNIT | 2471 — Multiplex and VoIP |
| CURRENT CPC | Multiplex Communication H04J 3/0667 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 43/106 (20130101) H04L 43/0858 (20130101) H04L 47/193 (20130101) H04L 69/163 (20130101) H04L 69/166 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10880035 | Bradley |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as Represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Timothy Bradley (Loogootee, Indiana) |
| ABSTRACT | A system is disclosed to identify authorized EO devices and unauthorized EO devices within a scene. The system responds with a variety of response actions including sending warning messages of the unauthorized EO devices, recording images and position of the unauthorized EO device. The system can further be configured to hamper the operation of the unauthorized EO devices detected within the scene. |
| FILED | Tuesday, August 04, 2015 |
| APPL NO | 14/817838 |
| ART UNIT | 2485 — Recording and Compression |
| CURRENT CPC | Weapon Sights; Aiming F41G 3/147 (20130101) F41G 7/224 (20130101) Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 13/005 (20130101) F41H 13/0062 (20130101) Electric Digital Data Processing G06F 21/6209 (20130101) G06F 2221/2101 (20130101) G06F 2221/2141 (20130101) G06F 2221/2149 (20130101) Image Data Processing or Generation, in General G06T 7/246 (20170101) G06T 2207/10016 (20130101) G06T 2207/10048 (20130101) G06T 2207/30232 (20130101) G06T 2207/30241 (20130101) Secret Communication; Jamming of Communication H04K 3/80 (20130101) H04K 3/822 (20130101) H04K 3/825 (20130101) Original (OR) Class H04K 2203/14 (20130101) Pictorial Communication, e.g Television H04N 7/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 10874678 | DeNardo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Sally J. DeNardo (El Macero, California); Gerald L. DeNardo (El Macero, California); Rodney L. Balhorn (Livermore, California) |
| ABSTRACT | This invention provides novel polydentate selective high affinity ligands (SHALs) that can be used in a variety of applications in a manner analogous to the use of antibodies. SHALs typically comprise a multiplicity of ligands that each bind different region son the target molecule. The ligands are joined directly or through a linker thereby forming a polydentate moiety that typically binds the target molecule with high selectivity and avidity. |
| FILED | Thursday, February 28, 2019 |
| APPL NO | 16/289464 |
| ART UNIT | 1628 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/675 (20130101) Original (OR) Class A61K 47/55 (20170801) A61K 47/60 (20170801) A61K 47/64 (20170801) A61K 47/545 (20170801) A61K 47/645 (20170801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875247 | Shusteff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Securitv. LLC (Livermore, California) |
| INVENTOR(S) | Maxim Shusteff (Livermore, California); Christopher M. Spadaccini (Livermore, California); Nicholas Fang (Livermore, California); Robert Matthew Panas (Livermore, California); Johannes Henriksson (Livermore, California); Brett Kelly (Livermore, California); Allison E. Browar (Livermore, California) |
| ABSTRACT | A multi-beam volumetric resin curing system and method for whole-volume additive manufacturing of an object includes a bath containing a photosensitive resin, a light source for producing a light beam, and a spatial light modulator which produces a phase- or intensity-modulated light beam by impressing a phase profile or intensity profile of an image onto a light beam received from the light source. The system and method also include projection optics which then produces multiple sub-image beams from the modulated light beam which are projected to intersect each other in the photosensitive resin to cure select volumetric regions of the resin in a whole-volume three-dimensional pattern representing the object. |
| FILED | Monday, July 17, 2017 |
| APPL NO | 15/651861 |
| ART UNIT | 1745 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) B29C 64/264 (20170801) B29C 64/268 (20170801) B29C 64/282 (20170801) Original (OR) Class B29C 64/286 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) Holographic Processes or Apparatus G03H 1/0005 (20130101) G03H 1/2205 (20130101) G03H 1/2294 (20130101) G03H 2001/0094 (20130101) G03H 2001/221 (20130101) G03H 2001/0491 (20130101) G03H 2001/2207 (20130101) G03H 2210/30 (20130101) G03H 2210/33 (20130101) G03H 2225/22 (20130101) G03H 2225/32 (20130101) G03H 2225/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875792 | Hawks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Steven Hawks (Livermore, California); Michael Stadermann (Pleasanton, California); Juan G. Santiago (Stanford, California); Ashwin Ramachandran (Stanford, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Steven Hawks (Livermore, California); Michael Stadermann (Pleasanton, California); Juan G. Santiago (Stanford, California); Ashwin Ramachandran (Stanford, California) |
| ABSTRACT | The present disclosure relates to a capacitive deionization (CDI) system for desalinating salt water. The system may have a capacitor formed by spaced apart first and second electrodes, which enable a fluid flow containing salt water to pass either between them or through them. An input electrical power source is configured to generate an electrical forcing signal between the two electrodes. The electrical forcing signal represents a periodic signal including at least one of voltage or current, and which can be represented as a Fourier series. One component of the Fourier series is a constant, and a second component of the Fourier series is a sinusoidal wave of non-zero frequency which has the highest amplitude of the additive components of the Fourier series. The amplitude of the sinusoidal wave component is between 0.85 and 1.25 times the amplitude of the periodic signal. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 16/418487 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4691 (20130101) Original (OR) Class C02F 2201/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875810 | Fernandez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| ASSIGNEE(S) | BATTELLE MEMORIAL INSTITUTE (Richland, Washington) |
| INVENTOR(S) | Carlos A. Fernandez (Kennewick, Washington); Phillip K. Koech (Richland, Washington); Wooyong Um (Richland, Washington); Vassiliki-Alexandra Glezakou (Richland, Washington); Jaehun Chun (Richland, Washington); M. Ian Childers (Richland, Washington); Manh Thuong Nguyen (Richland, Washington); Kenton A. Rod (Richland, Washington) |
| ABSTRACT | Examples of novel self-repairing cement-polymer composites and processes of making and using are detailed that address various problems in prior art cements. These matrices, compositions and materials that are more mechanically robust, thermally stable and chemically resistant and demonstrate better bonding to various structures and materials, than other self-healing cements known in the prior art. When in place under preselected conditions (the formulation of the slurry can be modified for optimal effectiveness under various conditions) the organic, cross linking and cement forming portions within the slurry form interconnecting chemical bonds and cures to form a self-repairing and self-re-adhering cement polymer composite matrix in the receiving location. |
| FILED | Monday, June 17, 2019 |
| APPL NO | 16/443576 |
| ART UNIT | 3674 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 24/32 (20130101) C04B 24/281 (20130101) C04B 28/04 (20130101) Original (OR) Class C04B 2103/40 (20130101) C04B 2111/74 (20130101) C04B 2111/2038 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875828 | Hohman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | James Nathan Hohman (Menlo Park, California); Mary S. Collins (Oakland, California); Tess E. Smidt (Berkeley, California) |
| ABSTRACT | Described are metal organochalcognides which are bulk nanomaterials, expressing monolayer properties in their as-synthesized states. Also described are certain novel metal organochalcogenide compositions. Further described are several methods of preparation of metal organochaleogenides, both solution- and vapor deposition-based, and methods of use of the resulting metal chalcogenides in assays and devices. |
| FILED | Friday, August 04, 2017 |
| APPL NO | 16/322830 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0272 (20130101) B01J 35/004 (20130101) Acyclic or Carbocyclic Compounds C07C 391/02 (20130101) Original (OR) Class C07C 395/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/06 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0002 (20130101) H01L 51/05 (20130101) H01L 51/009 (20130101) H01L 51/50 (20130101) H01L 51/0091 (20130101) H01L 51/4213 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875960 | Meng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
| INVENTOR(S) | Xiangtao Meng (Allentown, Pennsylvania); Soydan Ozcan (Oak Ridge, Tennessee); Halil Tekinalp (Knoxville, Tennessee) |
| ABSTRACT | A silane-modified polyester blend comprising a polyester polymer homogeneously blended with silane molecules containing two or three alkoxy groups bound to the silicon atom, wherein said silane molecules are present in said polyester blend in an amount of 0.05-20 wt % (or, e.g., 0.05-10 wt %, 0.05-5 wt %, or 0.05-2 wt %). The polyester polymer may, in particular embodiments, be a polyhydroxyalkanoate, terephthalate-based polyester, adipate-based, or succinate-based polyester. The silane molecule may be according to the formula (R2O)2SiR3R4, wherein R2 groups are independently selected from alkyl groups containing 1-4 carbon atoms; and R3 and R4 are independently selected from OR2 groups and alkyl groups containing 1-12 carbon atoms, provided that at least one of R3 and R4 is an alkyl group, wherein the alkyl group optionally includes one or more heteroatoms selected from oxygen, nitrogen, halogen, sulfur, phosphorus, and silicon. Methods for producing the silane-modified polyester blend are also described. |
| FILED | Thursday, August 23, 2018 |
| APPL NO | 16/110138 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/912 (20130101) C08G 63/916 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 5/5419 (20130101) C08K 5/5419 (20130101) C08K 5/5419 (20130101) Compositions of Macromolecular Compounds C08L 67/02 (20130101) C08L 67/03 (20130101) C08L 67/04 (20130101) C08L 67/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876041 | Enick |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Robert M. Enick (Bethel Park, Pennsylvania) |
| ABSTRACT | A method of treating a material to achieve at least one of reducing surface wettability of the material or reducing fluid transport through the material includes exposing the material to a composition including a solution of a polymer portion and carbon dioxide for a period of time. The polymer portion includes at least one of a polyfluoroacrylate or a copolymer of a fluoroacrylate and a comonomer. A pressure of the composition is maintained above the cloud point of the polymer portion at a concentration thereof in the carbon dioxide for the period of time. |
| FILED | Friday, April 12, 2019 |
| APPL NO | 16/382959 |
| ART UNIT | 3676 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 120/24 (20130101) C08F 220/24 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/487 (20130101) C09K 8/588 (20130101) C09K 8/594 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876124 | Melis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Anastasios Melis (El Cerrito, California); Cinzia Formighieri (Saugus, Massachusetts) |
| ABSTRACT | This invention provides compositions and methods for providing high product yield of transgenes expressed in cyanobacteria and microalgae. |
| FILED | Thursday, June 23, 2016 |
| APPL NO | 15/739101 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 2319/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/88 (20130101) C12N 15/74 (20130101) Original (OR) Class Enzymes C12Y 402/0302 (20130101) C12Y 402/03051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876139 | Haushalter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Robert W. Haushalter (Emeryville, California); Jay D. Keasling (Berkeley, California) |
| ABSTRACT | The present invention provides for a genetically modified host cell and related methods and materials for the biocatalytic production of an α,ω-dicarboxylic acids (DCAs) and/or mono-methyl ester derivatives of dicarboxylic acids (DCAMMEs). |
| FILED | Tuesday, May 28, 2019 |
| APPL NO | 16/423402 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/16 (20130101) C12N 9/1007 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/44 (20130101) Original (OR) Class C12P 7/6409 (20130101) C12P 7/6436 (20130101) C12P 17/08 (20130101) Enzymes C12Y 201/01197 (20130101) C12Y 301/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876142 | Söll et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Dieter Söll (Guilford, Connecticut); Caroline Aldag (Mannheim, Germany); Michael Hohn (Scotch Plains, New Jersey); Takahito Mukai (New Haven, Connecticut) |
| ABSTRACT | Non-naturally occurring tRNASec and methods of using them for recombinant expression of proteins engineered to include one or more selenocysteine residues are disclosed. The non-naturally occurring tRNASec can be used for recombinant manufacture of selenocysteine containing polypeptides encoded by mRNA without the requirement of an SECIS element. In some embodiments, selenocysteine containing polypeptides are manufactured by co-expressing a non-naturally occurring tRNASec a recombinant expression system, such as E. coli, with SerRS, EF-Tu, SelA, or PSTK and SepSecS, and an mRNA with at least one codon that recognizes the anticodon of the non-naturally occurring tRNASec. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/724678 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/113 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876167 | Snijders et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Antoine M. Snijders (Antioch, California); Xuan Yu Mao (Moraga, California); Matthew J. Lee (Moraga, California) |
| ABSTRACT | A biomarker panel of 12 genes based on expression levels. Methods for calculating prognostic scores and patient ranking based on their score and divided into two equal sized cohorts. Kaplan-Meier analysis and a log-rank test were used to determine differences in survival. |
| FILED | Friday, January 12, 2018 |
| APPL NO | 15/870693 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876200 | Erylimaz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | Osman L. Erylimaz (Plainfield, Illinois); Harpal Singh (Cuyahoga Falls, Ohio); Aaron C. Greco (Chicago, Illinois); Jair G. Ramirez Gonzalez (Naperville, Illinois); Ali Erdemir (Naperville, Illinois) |
| ABSTRACT | A hydrogenated diamond-like coating (“H-DLC”) for metallic substrates provides improved reliability. The H-DLC is relatively soft and elastic. Unlike hard and/or inelastic coatings in the prior art, the present coatings do not exhibit a loss of adhesion (delamination). A bonding layer may be used between the metallic substrate and the H-DLC. H-DLC coatings can, for example, be used in bearings and gears to reduce the occurrence of micropits and, ultimately, product failure. |
| FILED | Wednesday, February 28, 2018 |
| APPL NO | 15/908445 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/25 (20170801) C01B 32/26 (20170801) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/021 (20130101) C23C 14/024 (20130101) C23C 14/35 (20130101) C23C 14/0605 (20130101) C23C 14/0611 (20130101) Original (OR) Class C23C 14/0635 (20130101) C23C 14/3485 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876773 | Kariya et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Harumichi Arthur Kariya (Bellflower, California); Jeffrey P. Koplow (San Ramon, California); Wayne Lawrence Staats, Jr. (Livermore, California) |
| ABSTRACT | Embodiments disclosed herein relate to devices, systems, and methods for cooling and/or heating a medium as well as cooling and/or heating an environment containing the medium. More specifically, at least one embodiment includes a heat pump that may heat and/or cool a medium and, in some instances, may transfer heat from one location to another location. |
| FILED | Wednesday, August 21, 2019 |
| APPL NO | 16/546465 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 30/02 (20130101) Original (OR) Class F25B 39/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876898 | Murphy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Paul P. Woskov (Bedford, Massachusetts) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ryan D. Murphy (Tigard, Oregon); Eric C. Forrest (Sandia Park, New Mexico); Paul P. Woskov (Bedford, Massachusetts); Joshua Stanford (Albuquerque, New Mexico) |
| ABSTRACT | An apparatus for accurate measurement of surface and sub-surface temperatures of an object from a distance without contacting the object is provided. Illustrative embodiments provide for simultaneous measurement of thermal emission and emissivity in the mm-wave regime thereby enabling real-time non-contact measurement of emissivity. Corrected temperatures for the object which may be used for calibration of infrared thermographic cameras are determined from the measurement of emissivity. |
| FILED | Wednesday, August 08, 2018 |
| APPL NO | 16/058855 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/025 (20130101) Original (OR) Class G01J 2005/0051 (20130101) G01J 2005/0059 (20130101) G01J 2005/0062 (20130101) G01J 2005/0077 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876987 | Reyes et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Karla Rosa Reyes (Livermore, California); Josh A. Whaley (Livermore, California); Peter Anand Sharma (Albuquerque, New Mexico) |
| ABSTRACT | An apparatus for making in-situ electrical measurements of a sample while the sample is subjected to a temperature gradient between a first side of the sample and a second side of the sample. The apparatus comprises a first heater and a second heater that are positioned in contact with the first side of the sample and the second side of the sample, respectively. The first heater and the second heater comprise respective faces that each have electrical contacts embedded therein. Electrical measurements pertaining to the sample can be made by way of the electrical contacts embedded in the faces. A temperature at either side of the sample can be monitored by way of thermocouples positioned inside the heaters in proximity to the faces of the heaters. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196231 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/14 (20130101) Original (OR) Class G01N 27/041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877035 | Birnbaum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ICAGEN, LLC (San Diego, California) |
| ASSIGNEE(S) | ICAGEN, LLC (San Diego, California) |
| INVENTOR(S) | Eva R. Birnbaum (Los Alamos, New Mexico); Andrew T. Koppisch (Flagstaff, Arizona); Sharon M. Baldwin (Santa Fe, New Mexico); Benjamin P. Warner (Los Alamos, New Mexico); T. Mark McCleskey (Los Alamos, New Mexico); Jennifer A. Berger (Los Alamos, New Mexico); Jeffrey J. Stewart (Cary, North Carolina); Michael N. Harris (Los Alamos, New Mexico); Anthony K. Burrell (Naperville, Illinois) |
| ABSTRACT | X-ray fluorescence (XRF) spectrometry has been used for detecting binding events and measuring binding selectivities between chemicals and receptors. XRF may also be used for estimating the therapeutic index of a chemical. For estimating the binding selectivities of a chemical versus chemical analogs, for measuring post translational modification of proteins, and for drug manufacturing. |
| FILED | Wednesday, April 22, 2015 |
| APPL NO | 14/693094 |
| ART UNIT | 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/223 (20130101) G01N 23/2204 (20130101) G01N 33/566 (20130101) Original (OR) Class G01N 2223/076 (20130101) G01N 2500/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877194 | Beechem, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Thomas Edwin Beechem, III (Albuquerque, New Mexico); Michael Goldflam (Albuquerque, New Mexico); Stephen W. Howell (Albuquerque, New Mexico); David W. Peters (Albuquerque, New Mexico); Isaac Ruiz (Albuquerque, New Mexico); Paul Davids (Albuquerque, New Mexico) |
| ABSTRACT | An actively tunable optical filter can control the amplitude of reflected infrared light. The filter exploits the dependence of the excitation energy of plasmons in a continuous and unpatterned sheet of graphene, on the Fermi-level, which can be controlled by conventional electrostatic gating. An exemplary filter enables simultaneous modification of two distinct spectral bands whose positions are dictated by the device geometry and graphene plasmon dispersion. Within these bands, the reflected amplitude can be varied by over 15% and resonance positions can be shifted by over 90 cm−1. Electromagnetic simulations verify that tuning arises through coupling of incident light to graphene plasmons by a nanoantenna grating structure. Importantly, the tunable range is determined by a combination of graphene properties, device structure, and the surrounding dielectrics, which dictate the plasmon dispersion. Thus, the underlying design is applicable across a broad range of infrared frequencies. |
| FILED | Tuesday, January 16, 2018 |
| APPL NO | 15/872293 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/17 (20130101) G01N 21/553 (20130101) G01N 21/554 (20130101) Optical Elements, Systems, or Apparatus G02B 1/04 (20130101) G02B 5/008 (20130101) G02B 5/26 (20130101) G02B 5/204 (20130101) G02B 5/208 (20130101) Original (OR) Class Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/00 (20130101) G02F 2203/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877453 | Buenaventura et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NuScale Power, LLC (Corvallis, Oregon) |
| ASSIGNEE(S) | NuScale Power, LLC (Corvallis, Oregon) |
| INVENTOR(S) | Don Buenaventura (Seattle, Washington); Doug Bowman (Corvallis, Oregon) |
| ABSTRACT | Embodiments are directed to providing a user interface (UI) that streamlines and simplifies the process of monitoring critical power-generation module (PGM) parameters after a PGM assembly is shutdown. The UI displays, in real-time, indicators corresponding to one or more post-shutdown PGM parameters. The UI provides indications of whether the post-shutdown PGM parameters meet post-shutdown criteria of the PGM assembly. When a post-shutdown PGM parameter does not meet the post-shutdown criteria, a user alert is provided to the user. A protocol may additionally be provided to the user. In some embodiments, the protocol may enable the user to return the PGM assembly to a condition that satisfies the post-shutdown criteria. The protocol may be a safety protocol and/or an asset protection protocol. |
| FILED | Monday, February 04, 2019 |
| APPL NO | 16/267008 |
| ART UNIT | 2827 — Semiconductors/Memory |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 15/02 (20130101) G05B 19/048 (20130101) Original (OR) Class G05B 23/0267 (20130101) G05B 2219/2639 (20130101) G05B 2219/24015 (20130101) Systems Integrating Technologies Related to Power Network Operation, Communication or Information Technologies for Improving the Electrical Power Generation, Transmission, Distribution, Management or Usage, i.e Smart Grids Y04S 10/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10878977 | Kumta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Prashant Nagesh Kumta (Pittsburgh, Pennsylvania); Wei Wang (Pittsburgh, Pennsylvania); Prashanth Jampani Hanumantha (Mountain View, California); Bharat Gattu (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions including nano-particles and a nano-structured support matrix, methods of their preparation and applications thereof. The compositions of the present invention are particularly suitable for use as anode material for lithium-ion rechargeable batteries. The nano-structured support matrix can include nanotubes, nanowires, nanorods, and mixtures thereof. The composition can further include a substrate on which the nano-structured support matrix is formed. The substrate can include a current collector material. |
| FILED | Monday, June 03, 2019 |
| APPL NO | 16/429554 |
| ART UNIT | 1723 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/04 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/134 (20130101) H01M 10/0525 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/7011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879012 | Schulz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Philip Schulz (Massy, France); Joseph Jonathan Berry (Boulder, Colorado); Arrelaine Allen Dameron (Boulder, Colorado); Paul Francois Ndione (Lakewood, Colorado) |
| ABSTRACT | The present application discloses devices that include a perovskite layer, a first layer that includes an oxide, and an interface layer, where the interface layer is positioned between the first layer and the perovskite layer, the interface layer is in physical contact with both the first layer and the perovskite layer, and the interface layer consists essentially of the oxide. |
| FILED | Monday, June 04, 2018 |
| APPL NO | 15/997403 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/0036 (20130101) H01G 9/2009 (20130101) H01G 9/2018 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0001 (20130101) H01L 51/0009 (20130101) H01L 51/0077 (20130101) H01L 51/4226 (20130101) H01L 51/4253 (20130101) H01L 2251/303 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879479 | Hammond et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SolarWindow Technologies, Inc. (Vestal, New York); Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | SolarWindow Technologies, Inc. (Vestal, New York); Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Scott R. Hammond (Seattle, Washington); Marinus Franciscus Antonius Maria van Hest (Lakewood, Colorado) |
| ABSTRACT | Systems and methods for organic semiconductor devices with sputtered contact layers are provided. In one embodiment, an organic semiconductor device comprises: a first contact layer (140) comprising a first sputter-deposited transparent conducting oxide; an electron transport layer (130) interfacing with the first contact layer; a second contact layer (110) comprising a second sputter-deposited transparent conducting oxide; a hole transport layer interfacing with the second contact layer; and an organic semiconductor active layer (120) having a first side facing the electron transport layer and an opposing second side facing the hole transport layer; wherein either the electron transport layer or the hole transport layer comprises a buffering transport layer. |
| FILED | Friday, March 03, 2017 |
| APPL NO | 16/081390 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0008 (20130101) H01L 51/0021 (20130101) H01L 51/442 (20130101) Original (OR) Class H01L 51/5012 (20130101) H01L 51/5056 (20130101) H01L 51/5072 (20130101) H01L 51/5215 (20130101) H01L 51/5234 (20130101) H01L 2251/305 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879526 | Li et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Yuzhang Li (Stanford, California); Kai Yan (Stanford, California); Zhenda Lu (Stanford, California); Yi Cui (Stanford, California) |
| ABSTRACT | A conformal graphene-encapsulated battery electrode material is formed by: (1) coating a battery electrode material with a metal catalyst to form a metal catalyst-coated battery electrode material; (2) growing graphene on the metal catalyst-coated battery electrode material to form a graphene cage encapsulating the metal catalyst-coated battery electrode material; and (3) at least partially removing the metal catalyst to form a void inside the graphene cage. |
| FILED | Thursday, June 09, 2016 |
| APPL NO | 15/178366 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/049 (20130101) H01M 4/134 (20130101) H01M 4/366 (20130101) Original (OR) Class H01M 4/386 (20130101) H01M 4/387 (20130101) H01M 4/0471 (20130101) H01M 4/483 (20130101) H01M 4/0492 (20130101) H01M 4/625 (20130101) H01M 10/052 (20130101) H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879533 | Bridges et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Craig A. Bridges (Oak Ridge, Tennessee); Mariappan Parans Paranthaman (Knoxville, Tennessee); Gabriel M. Veith (Knoxville, Tennessee); Zhonghe Bi (Oak Ridge, Tennessee) |
| ABSTRACT | Compositions and methods of making compositions are provided for nitride- and/or oxide-modified electrode compositions. In certain embodiments, the nitride- and/or oxide-modified compositions have the general formula M1-zM′zOaF3-xNy. Such compositions may be used as bulk or surface compositions, and used in a battery as the anode or cathode. In other embodiments, the electrode includes a surface coating composition selected from metal nitrides and metal oxides, and a core composition having the formula M1-zM′zOaF3-x, or an oxide fluoride. |
| FILED | Monday, July 02, 2018 |
| APPL NO | 16/025637 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/58 (20130101) Original (OR) Class H01M 4/136 (20130101) H01M 4/366 (20130101) H01M 10/054 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879552 | Koplow |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Jeffrey P. Koplow (San Ramon, California) |
| ABSTRACT | A electrochemical storage device, referred to herein as a radical-ion battery, is described. The radical-ion battery includes an electrolyte, first free radicals, and second free radicals, wherein the first free radicals and the second free radicals are different chemical species. The radical-ion battery also includes a separator that allows select ions to pass therethrough, but separates the electrolyte from the second free radicals. |
| FILED | Thursday, February 16, 2017 |
| APPL NO | 16/098432 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 2/40 (20130101) H01M 2/1646 (20130101) H01M 8/143 (20130101) Original (OR) Class H01M 8/144 (20130101) H01M 8/184 (20130101) H01M 8/188 (20130101) H01M 8/0202 (20130101) H01M 8/04089 (20130101) H01M 8/04186 (20130101) H01M 8/04201 (20130101) H01M 10/38 (20130101) H01M 10/399 (20130101) H01M 10/4214 (20130101) H01M 2220/10 (20130101) H01M 2250/10 (20130101) H01M 2300/002 (20130101) H01M 2300/0048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879839 | Ayyanar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Rajapandian Ayyanar (Gilbert, Arizona); Yinglai Xia (Tempe, Arizona); Jinia Roy (Tempe, Arizona) |
| ABSTRACT | Power converter circuitry includes a direct current (DC) input comprising a first DC input node and a second DC input node, an alternating current (AC) output comprising a first AC output node coupled to the first DC input node and a second AC output node, a first boost switch coupled between the second DC input node and a boost intermediate node, a second boost switch coupled between the boost intermediate node and a common node, a boost inductor coupled between the boost intermediate node and the first DC input node, a link capacitor coupled between the second DC input node and the common node, a first half-bridge switch coupled between the second DC input node and a half-bridge intermediate node, a second half-bridge switch coupled between the half-bridge intermediate node and the common node, and a half-bridge inductor coupled between the half-bridge intermediate node and the second AC output node. |
| FILED | Monday, December 05, 2016 |
| APPL NO | 15/780840 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/383 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/158 (20130101) H02M 3/1582 (20130101) H02M 7/487 (20130101) H02M 7/537 (20130101) H02M 7/4826 (20130101) H02M 7/5387 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/32 (20141201) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10880984 | Kroc |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois) |
| INVENTOR(S) | Thomas Kroc (Batavia, Illinois) |
| ABSTRACT | A magnetic apparatus and a method of operating the magnetic apparatus can include a scanning electromagnet that redirects a beam of charged particles, a vacuum chamber that prevents the atmosphere from interfering with the charged particles; and, a parallelizing permanent magnet array for parallelizing the beam of charged particles. The parallelizing permanent magnet array can be located proximate to a target comprising a Bremsstrahlung target or an object that is being irradiated. The magnetic field of the scanning electromagnet can be variable to produce all angles necessary to sweep the beam of charged particles across the target and the parallelizing permanent magnet array can be configured from a magnetic material that does not require an electric current. |
| FILED | Friday, May 31, 2019 |
| APPL NO | 16/428664 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/04 (20130101) Original (OR) Class H05H 2007/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 10874764 | Bonassar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (Ithaca, New York) |
| INVENTOR(S) | Lawrence J. Bonassar (Ithaca, New York); Roger Hartl (New York, New York); Robert D. Bowles (Ithaca, New York); Harry H. Gebhard (Tuebingen, Germany) |
| ABSTRACT | The present invention relates to a tissue-engineered intervertebral disc (IVD) suitable for total disc replacement in a mammal and methods of fabrication. The IVD comprises a nucleus pulposus structure comprising a first population of living cells that secrete a hydrophilic protein and an annulus fibrosis structure surrounding and in contact with the nucleus pulposus structure, the annulus fibrosis structure comprising a second population of living cells and type I collagen. The collagen fibrils in the annulus fibrosis structure are circumferentially aligned around the nucleus pulposus region due to cell-mediated contraction in the annulus fibrosis structure. Also disclosed are methods of fabricating tissue-engineered intervertebral discs. |
| FILED | Sunday, June 16, 2019 |
| APPL NO | 16/442535 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/442 (20130101) A61F 2002/444 (20130101) A61F 2002/445 (20130101) A61F 2002/4435 (20130101) A61F 2002/4445 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/32 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/20 (20130101) A61L 27/22 (20130101) A61L 27/24 (20130101) A61L 27/44 (20130101) A61L 27/52 (20130101) A61L 27/3658 (20130101) Original (OR) Class A61L 27/3691 (20130101) A61L 27/3817 (20130101) A61L 27/3856 (20130101) A61L 27/3886 (20130101) A61L 2430/38 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874811 | Gholami et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Autonomous Healthcare, Inc. (Hoboken, New Jersey) |
| ASSIGNEE(S) | Autonomous Healthcare, Inc. (Hoboken, New Jersey) |
| INVENTOR(S) | Behnood Gholami (Hoboken, New Jersey); Timothy S. Phan (Brooklyn, New York) |
| ABSTRACT | The present disclosure describes a system that automatically detects patient-ventilator asynchrony and trends in patient-ventilator asynchrony. The present disclosure describes a framework that uses pressure, flow, and volume waveforms to detect patient-ventilator asynchrony and the presence of secretions in the ventilator circuit. |
| FILED | Friday, November 09, 2018 |
| APPL NO | 16/762224 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/024 (20170801) Original (OR) Class A61M 16/026 (20170801) A61M 2016/0027 (20130101) A61M 2016/0033 (20130101) A61M 2205/52 (20130101) A61M 2205/502 (20130101) A61M 2205/3379 (20130101) A61M 2205/3584 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10874997 | Weitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David A. Weitz (Bolton, Massachusetts); Julian W. P. Thiele (Dresden, Germany); Adam R. Abate (Daly City, California) |
| ABSTRACT | The present invention generally relates to emulsions, and more particularly, to multiple emulsions. In one aspect, multiple emulsions are formed by urging a fluid into a channel, e.g., by causing the fluid to enter the channel as a “jet.” Multiple fluids may flow through a channel collinearly before multiple emulsion droplets are formed. The fluidic channels may also, in certain embodiments, include varying degrees of hydrophilicity or hydrophobicity. In some cases, the average cross-sectional dimension may change, e.g., at an intersection. Unexpectedly, systems such as those described herein may be used to encapsulate fluids in single or multiple emulsions that are difficult or impossible to encapsulate using other techniques, such as fluids with low surface tension, viscous fluids, or viscoelastic fluids. Other aspects of the invention are generally directed to methods of making and using such systems, kits involving such systems, emulsions created using such systems, or the like. |
| FILED | Friday, July 21, 2017 |
| APPL NO | 15/656415 |
| ART UNIT | 1764 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) Original (OR) Class B01F 13/0062 (20130101) B01F 13/0084 (20130101) B01F 2003/0838 (20130101) B01F 2215/045 (20130101) B01F 2215/0459 (20130101) Technical Subjects Covered by Former US Classification Y10T 137/0318 (20150401) Y10T 137/85938 (20150401) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875248 | Afshar Mohajer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Fayetteville, Arkansas) |
| ASSIGNEE(S) | Board Of Trustees Of The University Of Arkansas (Fayetteville, Arkansas) |
| INVENTOR(S) | Mahyar Afshar Mohajer (Fayetteville, Arkansas); Josue Goss (Fayetteville, Arkansas); Dipankar Choudhury (Fayetteville, Arkansas); Min Zou (Fayetteville, Arkansas); Shelby Robert Maddox (Fayetteville, Arkansas) |
| ABSTRACT | The present invention relates generally to methods of fabricating surface topography based on a scanned surface topography. The method converts 3D scanned surface topography data that have submicron resolution to digital formats that can be stored, manipulated, or tiled, and used as an input for replicating the surface topography with submicron resolution on another substrate. The digitized surface topography data is then converted to input for 1) 3D printing to replicate the scanned surface topography with submicron resolution, with or without a subsequent coating layer or layers to impart additional properties and/or features, 2) 3D printing a master that replicates the scanned surface topography with submicron resolution, which will be used for fast replica molding of the surface topography onto another substrate, and 3) creating a photomask with submicron resolution for transferring the surface topography to a metal substrate surface through subsequent photolithography and etching processes. |
| FILED | Monday, February 11, 2019 |
| APPL NO | 16/273103 |
| ART UNIT | 1716 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/30 (20170801) Original (OR) Class B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875840 | Fox et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joseph Fox (Landenberg, Pennsylvania); Xinqiao Jia (Newark, Delaware); Will Trout (Wilmington, Delaware); Joel Rosenthal (Newark, Delaware); Han Zhang (Columbia, Maryland); Yinzhi Fang (Newark, Delaware); Colin Thorpe (Newark, Delaware); Shuang Liu (Newark, Delaware); Yixin Xie (Newark, Delaware) |
| ASSIGNEE(S) | UNIVERSITY OF DELAWARE (Newark, Delaware) |
| INVENTOR(S) | Joseph Fox (Landenberg, Pennsylvania); Xinqiao Jia (Newark, Delaware); Will Trout (Wilmington, Delaware); Joel Rosenthal (Newark, Delaware); Han Zhang (Columbia, Maryland); Yinzhi Fang (Newark, Delaware); Colin Thorpe (Newark, Delaware); Shuang Liu (Newark, Delaware); Yixin Xie (Newark, Delaware) |
| ABSTRACT | A method for catalytically converting a dihydrotetrazine 1 into a tetrazine 2, wherein one R group on the dihydrotetrazine 1 is a substituted or unsubstituted aryl, heteroaryl, alkyl, alkenyl, alkynyl, carbonyl, or heteroatom-containing group, and the other R group is selected from the group consisting of H and substituted or unsubstituted aryl, heteroaryl, alkyl, alkenyl, alkynyl, carbonyl,- or heteroatom-containing groups; 1, 2 wherein the method comprises oxidizing dihydrotetrazine 1 in a reaction medium in the presence of a catalyst and a stoichiometric oxidant. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 16/062423 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 257/08 (20130101) C07D 401/04 (20130101) C07D 401/14 (20130101) Original (OR) Class C07D 403/04 (20130101) C07D 403/14 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/165 (20130101) Enzymes C12Y 111/01007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875895 | Chmielewski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jean Anne Chmielewski (Lafayette, Indiana); Mohamed Seleem (West Lafayette, Indiana) |
| ABSTRACT | The present disclosure relates to novel antibacterial cell-penetrating peptides and derivatives, and methods to make and use the novel antibacterial cell-penetrating peptides and derivatives. The novel antibacterial cell-penetrating peptides of the present invention with shorter linker between a pyrrolidine ring and a guanidine group provide unexpectedly higher potency against a broader scope of bacterial. |
| FILED | Wednesday, November 13, 2019 |
| APPL NO | 16/682004 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7036 (20130101) A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 47/552 (20170801) A61K 49/0056 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Peptides C07K 9/008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876142 | Söll et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| INVENTOR(S) | Dieter Söll (Guilford, Connecticut); Caroline Aldag (Mannheim, Germany); Michael Hohn (Scotch Plains, New Jersey); Takahito Mukai (New Haven, Connecticut) |
| ABSTRACT | Non-naturally occurring tRNASec and methods of using them for recombinant expression of proteins engineered to include one or more selenocysteine residues are disclosed. The non-naturally occurring tRNASec can be used for recombinant manufacture of selenocysteine containing polypeptides encoded by mRNA without the requirement of an SECIS element. In some embodiments, selenocysteine containing polypeptides are manufactured by co-expressing a non-naturally occurring tRNASec a recombinant expression system, such as E. coli, with SerRS, EF-Tu, SelA, or PSTK and SepSecS, and an mRNA with at least one codon that recognizes the anticodon of the non-naturally occurring tRNASec. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/724678 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/113 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876193 | Guo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Chunlei Guo (Rochester, New York); Anatoliy Y. Vorobyev (St. Catharines, Canada) |
| ASSIGNEE(S) | UNIVERSITY OF ROCHESTER (Rochester, New York) |
| INVENTOR(S) | Chunlei Guo (Rochester, New York); Anatoliy Y. Vorobyev (St. Catharines, Canada) |
| ABSTRACT | Methods for making a material superwicking and/or superwetting (superhydrophyllic) involving creating one or more indentations in the surface of the material that have a micro-rough surface of protrusions, cavities, spheres, rods, or other irregularly shaped features having heights and/or widths on the order of 0.5 to 100 microns and the micro-rough surface having a nano-rough surface of protrusions, cavities, spheres, rods, and other irregularly shaped features having heights and/or widths on the order of 1 to 500 nanometers. Superwicking and/or superwetting materials having micro-rough and nano-rough surface indentations, including metals, glass, enamel, polymers, semiconductors, and others. |
| FILED | Thursday, September 06, 2012 |
| APPL NO | 13/604951 |
| ART UNIT | 1735 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0006 (20130101) B23K 26/355 (20180801) B23K 26/0624 (20151001) B23K 2103/08 (20180801) B23K 2103/10 (20180801) B23K 2103/12 (20180801) B23K 2103/14 (20180801) B23K 2103/16 (20180801) B23K 2103/42 (20180801) B23K 2103/50 (20180801) B23K 2103/52 (20180801) B23K 2103/56 (20180801) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) B82Y 40/00 (20130101) Modifying the Physical Structure of Ferrous Metals; General Devices for Heat Treatment of Ferrous or Non-ferrous Metals or Alloys; Making Metal Malleable, e.g by Decarburisation or Tempering C21D 1/09 (20130101) C21D 8/0294 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 3/00 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 428/12993 (20150115) Y10T 428/24355 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876688 | Weitz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David A. Weitz (Bolton, Massachusetts); Esther Amstad (Lausanne, Switzerland) |
| ABSTRACT | The present invention generally relates to the production of fluidic droplets. Certain aspects of the invention are generally directed to systems and methods for creating droplets by flowing a fluid from a first channel to a second channel through a plurality of side channels. The fluid exiting the side channels into the second channel may form a plurality of droplets, and in some embodiments, at very high droplet production rates. In addition, in some aspects, double or higher-order multiple emulsions may also be formed. In some embodiments, this may be achieved by forming multiple emulsions through a direct, synchronized production method and/or through the formation of a single emulsion that is collected and re-injected into a second microfluidic device to form double emulsions. |
| FILED | Tuesday, October 30, 2018 |
| APPL NO | 16/175395 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 5/0478 (20130101) B01F 13/0059 (20130101) B01F 13/0061 (20130101) B01F 2215/0431 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0241 (20130101) B01L 3/502784 (20130101) B01L 2200/0673 (20130101) B01L 2300/0816 (20130101) Fluid Dynamics, i.e Methods or Means for Influencing the Flow of Gases or Liquids F15D 1/02 (20130101) Pipe-line Systems; Pipe-lines F17D 1/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876886 | Dumont et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | YouV Labs, Inc. (New York, New York) |
| ASSIGNEE(S) | YouV Labs, Inc. (New York, New York) |
| INVENTOR(S) | Emmanuel Dumont (New York, New York); Peter Kaplan (Montclair, New Jersey) |
| ABSTRACT | Methods of accurately estimating erythemaly-weighted UV exposure, such as the UV Index, and sensors adapted for the same. |
| FILED | Monday, October 21, 2019 |
| APPL NO | 16/659427 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/16 (20130101) G01J 1/44 (20130101) G01J 1/429 (20130101) Original (OR) Class G01J 1/0488 (20130101) G01J 2001/444 (20130101) G01J 2001/1657 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876946 | Ndukaife et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Justus C. Ndukaife (West Lafayette, Indiana); Alexandra Boltasseva (West Lafayette, Indiana); Agbai Nnanna (Crown Point, Indiana) |
| ABSTRACT | An apparatus for trapping and sensing nanoparticles using plasmonic nanopores, comprising a conductive transparent layer, a conductive film layer mounted to a substrate, the film layer comprising a plurality of nanopores for trapping nanoparticles contained in a fluid situated between the conductive transparent layer and the conductive film layer, and an electric field source connected between the transparent layer and the film layer. |
| FILED | Tuesday, December 17, 2019 |
| APPL NO | 16/717842 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) B82Y 30/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/00 (20130101) Original (OR) Class G01N 2015/0038 (20130101) G01N 2015/0053 (20130101) Optical Elements, Systems, or Apparatus G02B 5/008 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876971 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Chenxiang Lin (Cambridge, Massachusetts); Chao Li (Boston, Massachusetts); William M. Shih (Cambridge, Massachusetts); Peng Yin (Brookline, Massachusetts); Ralf Jungmann (Munich, Germany) |
| ABSTRACT | Provided herein are, inter alia, barcode probes comprised of transiently or stably fluorescently labeled nucleic acid nanostructures that are fully addressable and able to be read using standard fluorescent microscope and methods of use thereof including methods of use as detectable labels for probes. |
| FILED | Thursday, June 14, 2018 |
| APPL NO | 16/008719 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 15/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6825 (20130101) C12Q 1/6825 (20130101) C12Q 2563/107 (20130101) C12Q 2563/157 (20130101) C12Q 2563/185 (20130101) C12Q 2565/102 (20130101) C12Q 2565/601 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6486 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877193 | Magnusson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert Magnusson (Arlington, Texas); Manoj Niraula (Benbrook, Texas); Yeong Hwan Ko (Grand Prairie, Texas); Kyu Jin Lee (Euless, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Magnusson (Arlington, Texas); Manoj Niraula (Benbrook, Texas); Yeong Hwan Ko (Grand Prairie, Texas); Kyu Jin Lee (Euless, Texas) |
| ABSTRACT | Unpolarized broadband reflectors enabled by a serial arrangement of a pair of polarized subwavelength gratings are disclosed. Device illustrations include partially-etched crystalline-silicon films on quartz substrates and amorphous silicon films on glass. The individual reflectors exhibit extremely wide spectral reflection bands in one polarization. By arranging two such reflectors sequentially with orthogonal periodicities, there results an unpolarized spectral band that exceeds those of the individual polarized bands. In the prototypes disclosed, there results zero-order reflectance exceeding 97% under unpolarized light incidence over a 500-nm-wide wavelength band. This wideband represents a ˜44% fractional band in the near infrared spectral band. The elemental polarization-sensitive reflectors based on one-dimensional resonant gratings have simple design, robust performance, and are straightforward to fabricate. Hence, this technology is a promising alternative to traditional multilayer thin-film reflectors especially at longer wavelengths of light where multilayer deposition may be infeasible or impractical. |
| FILED | Friday, September 16, 2016 |
| APPL NO | 15/267830 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/1861 (20130101) Original (OR) Class G02B 27/4277 (20130101) G02B 27/4288 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877208 | Chiles et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | Universty of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Jeffrey Chiles (Boulder, Colorado); Sasan Fathpour (Orlando, Florida) |
| ABSTRACT | A polarization-sensitive photonic splitter may include a lower cladding layer and a device layer formed from a first waveguide supporting TE and TM light, a second waveguide, a third waveguide, and a transition core. The first waveguide core and the second waveguide core are formed from one of a first core structure or a second core structure, and the third waveguide is formed from the other structure. The first core structure has an index of refraction nM. The second core structure is formed as alternating layers providing an effective index of refraction for TE light nTE and an effective index of refraction for TM light nTM, where nTM<nM<nTE. The transition core is formed from the first core structure adjacent to the second core structure and is coupled to the first transition core at one and the second and third transition cores at the other end. |
| FILED | Tuesday, January 07, 2020 |
| APPL NO | 16/735758 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/285 (20130101) G02B 6/0056 (20130101) G02B 6/125 (20130101) G02B 6/126 (20130101) G02B 6/02109 (20130101) Original (OR) Class G02B 6/2726 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877209 | Chiles et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | Univeristy of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Jeffrey Chiles (Boulder, Colorado); Sasan Fathpour (Orlando, Florida) |
| ABSTRACT | A photonic device may include a lower cladding layer and a device layer. The device layer may include a first waveguide supporting TE and TM light, and a second waveguide, where a portion of a second waveguide core is proximate to a first waveguide core to provide evanescent coupling. The first waveguide core is formed from one of a first core structure or a second core structure, and the second waveguide core is formed from the other structure. The first core structure has an index of refraction nM. The second core structure is formed as alternating layers providing an effective index of refraction for TE polarized light nTE and an effective index of refraction for TM polarized light nTM, where nTM<nM<nTE such that one of TM or TE light is preferentially evanescently coupled between the first waveguide and the second waveguide. |
| FILED | Tuesday, January 07, 2020 |
| APPL NO | 16/735780 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/285 (20130101) G02B 6/0056 (20130101) G02B 6/125 (20130101) G02B 6/126 (20130101) G02B 6/02109 (20130101) Original (OR) Class G02B 6/2726 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10878935 | Reed et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Jennifer L. Reed (Madison, Wisconsin); Christopher J. Tervo (Madison, Wisconsin) |
| ABSTRACT | Systems and methods for determining genetic variations of an organism for performing a physiological function. The systems include a number of modules that can be integrated into existing metabolic engineering algorithms. The methods include use of the modules. The physiological function may include growth, compound production, and/or metabolic reaction flux, among others. |
| FILED | Tuesday, November 24, 2015 |
| APPL NO | 14/950131 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/00 (20190201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879156 | Dutta |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | Washington State University (Pullman, Washington) |
| INVENTOR(S) | Indranath Dutta (Pullman, Washington) |
| ABSTRACT | A method comprising incorporating indium into an entire Sn film for preventing the growth of whiskers from the Sn film, wherein the Sn film is applied to a metallic substrate. The indium is present in the entire thickness of the Sn film. |
| FILED | Tuesday, May 31, 2016 |
| APPL NO | 15/169194 |
| ART UNIT | 2847 — Electrical Circuits and Systems |
| CURRENT CPC | Alloys C22C 13/00 (20130101) Changing the Physical Structure of Non-ferrous Metals and Non-ferrous Alloys C22F 1/16 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/30 (20130101) C25D 5/505 (20130101) C25D 7/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/49582 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879283 | Leon-Salas |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Walter Daniel Leon-Salas (West Lafayette, Indiana) |
| ABSTRACT | An image sensor is provided, the image sensor comprising a plurality of photo-diode pixels arranged in a two-dimensional array, an energy harvesting output bus connected to the plurality of photo-diode pixels, an image sensing output bus connected to the plurality of photo-diode pixels, and a plurality of switching buses connected to the plurality of photo-diode pixels to direct an output of a varying percentage of the plurality of photo-diode pixels to either the energy harvesting output bus or the image sensing output bus. |
| FILED | Tuesday, July 16, 2019 |
| APPL NO | 16/513598 |
| ART UNIT | 2851 — Printing/Measuring and Testing |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/142 (20130101) H01L 27/14609 (20130101) Original (OR) Class H01L 27/14643 (20130101) H01L 31/053 (20141201) H01L 31/02021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879445 | Alemán et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Benjamín J. Alemán (Eugene, Oregon); Joshua E. Ziegler (Eugene, Oregon) |
| ABSTRACT | A quantum emitter device is composed of a hole milled in a layer of hexagonal boron nitride (hBN) on a substrate made of silicon dioxide. The hole preferably has a side wall angle 1.1°±0.28° from the horizontal, has an oval shape with minor axis 516 nm±20 nm and major axis 600 nm±20 nm, and/or has a depth 4 nm±1 nm. The hBN layer preferably has a total thickness of 5-10 nm. The holes may be fabricated using a gallium focused ion beam, a helium focused ion beam, electron beam directed etching, or photolithography and reactive ion etch (RIE) with sidewall tapering. |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 16/788685 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/12 (20130101) Original (OR) Class Transmission H04B 10/70 (20130101) H04B 10/291 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879539 | Murphy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Marc Murphy (Blaine, Minnesota); Ryo H. Wakabayashi (Santa Clara, California); R. Bruce Van Dover (Ithaca, New York); Héctor D. Abruña (Ithaca, New York); Francis J. Disalvo (Ithaca, New York) |
| ABSTRACT | A metal oxide compound of formula (I): MnxMyRu1-(x+y)O2 (I) is a single phase rutile-type structure, where M is Co, Ni, or Fe, or a combination thereof, x>0, y≥0, and 0.02≤(x+y)≤0.30. Related electro-catalysts, devices, and processes are also provided. |
| FILED | Wednesday, June 07, 2017 |
| APPL NO | 16/303010 |
| ART UNIT | 1722 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/9016 (20130101) Original (OR) Class H01M 8/083 (20130101) H01M 8/1004 (20130101) H01M 12/08 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879702 | Bou-Zeid et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | Trustees of Princeton University (Princeton, New Jersey) |
| INVENTOR(S) | Elie Bou-Zeid (Princeton, New Jersey); Mostafa Momen (Princeton, New Jersey) |
| ABSTRACT | A system and method for performing novel wind forecasting that is particularly accurate for forecasting over short-term time periods, e.g., over the next 1-5 hours. Such wind forecasting is particularly advantageous in wind energy applications. The disclosed method is anchored in a robust physical model of the wind variability in the atmospheric boundary layer (ABL). The disclosed method approach leverages a physical framework based on the unsteady dynamics of earth's atmosphere, and drives forecasting as a function of previously-observed atmospheric condition data observed at the same location for which a wind forecast is desired. |
| FILED | Monday, March 28, 2016 |
| APPL NO | 15/557610 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 5/14 (20130101) Meteorology G01W 1/10 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 13/048 (20130101) G05B 2219/2619 (20130101) Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/386 (20130101) Original (OR) Class Dynamo-electric Machines H02K 7/183 (20130101) Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 9/48 (20130101) H02P 2101/15 (20150115) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879983 | Ma et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Yunfei Ma (Santa Clara, California); Zhihong Luo (Berkeley, California); Christoph Steiger (Berlin, Germany); Carlo Giovanni Traverso (Newton, Massachusetts); Fadel Adib (Cambridge, Massachusetts) |
| ABSTRACT | Multiple antennas of a beamformer may simultaneously transmit wireless signals at different frequencies. The signals may comprise synchronized, identical wireless commands, each at a different carrier frequency. The transmitted signals may constructively and destructively interfere with each other at a receiver antenna, to form a beat signal. When the transmitted signals constructively interfere, the beat signal may cause a voltage in the receiver to exceed a threshold voltage. The threshold voltage may be a minimum voltage at which a device, which is operatively connected to the receiver antenna, is able to perform energy harvesting or wireless communication. The beamformer may operate under blind channel conditions, because the transmitted frequencies may be selected in such a way as to maximize peak power delivered under all possible channel conditions. The beamformer may deliver wireless power to a sensor or actuator that is located deep inside bodily tissue. |
| FILED | Sunday, May 17, 2020 |
| APPL NO | 16/876068 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/10217 (20130101) Transmission H04B 7/0617 (20130101) Original (OR) Class H04B 13/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10880330 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana); Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | XiaoFeng Wang (Bloomington, Indiana); Kan Yuan (Bloomington, Indiana); Xiaojing Liao (Atlanta, Georgia); Raheem A. Beyah (Atlanta, Georgia) |
| ABSTRACT | System and method for detecting an infected website are disclosed. A semantic finder receives top-level domains and identifies keywords of the top-level domains representing a predetermined semantics. The keywords are compared with irrelevant bad terms to find at least one irrelevant term. An inconsistency searcher searches the top-level domains and detects at least one fully-qualified domain name carrying the at least one irrelevant term. A context analyzer evaluates context information associated with the irrelevant term, identifies at least one frequently-used term identified in the context information, and determines whether the at least one frequently-used term is unrelated to a generic content of the at least one fully-qualified domain name An irrelevant bad term collector extracts the at least one frequently-used term unrelated to the generic content and adds the extracted frequently-used term to an irrelevant bad term list for detecting the infected website. |
| FILED | Friday, May 18, 2018 |
| APPL NO | 15/983093 |
| ART UNIT | 2419 — Recording and Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9535 (20190101) G06F 21/566 (20130101) G06F 40/30 (20200101) G06F 40/205 (20200101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1416 (20130101) H04L 63/1483 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10880541 | Cohen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Adobe Inc. (San Jose, California) |
| ASSIGNEE(S) | Adobe Inc. (San Jose, California) |
| INVENTOR(S) | Scott D. Cohen (Sunnyvale, California); Brian L. Price (Pleasant Grove, Utah); Gowri Sornanath (Newark, Delaware) |
| ABSTRACT | Stereo correspondence and depth sensor techniques are described. In one or more implementations, a depth map generated by a depth sensor is leveraged as part of processing of stereo images to assist in identifying which parts of stereo images correspond to each other. The depth map, for instance, may be utilized to assist in identifying depth discontinuities in the stereo images. Additionally, techniques may be employed to align the depth discontinuities identified from the depth map to image edges identified from the stereo images. Techniques may also be employed to suppress image edges that do not correspond to the depth discontinuities of the depth map in comparison with image edges that do correspond to the depth discontinuities as part of the identification. |
| FILED | Tuesday, August 27, 2019 |
| APPL NO | 16/552883 |
| ART UNIT | 2484 — Recording and Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0346 (20130101) Image Data Processing or Generation, in General G06T 7/593 (20170101) G06T 2207/10012 (20130101) G06T 2207/10028 (20130101) Pictorial Communication, e.g Television H04N 13/122 (20180501) H04N 13/239 (20180501) H04N 13/271 (20180501) Original (OR) Class H04N 2013/0081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10881034 | Maroo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shalabh C. Maroo (Syracuse, New York); An Zou (Cortland, New York); Manish Gupta (Syracuse, New York) |
| ASSIGNEE(S) | Syracuse University (Syracuse, New York) |
| INVENTOR(S) | Shalabh C. Maroo (Syracuse, New York); An Zou (Cortland, New York); Manish Gupta (Syracuse, New York) |
| ABSTRACT | A cooling device for a heat source, such as an electronic component, has a single or set of nano- and/or micro-sized channel(s) connected to a single or multiple reservoir(s). The heat source causes nucleation within a channel, and a vapor bubble forms removing heat from the heat source via evaporation of liquid to vapor in the bubble and condensation of the generated vapor at the cooler ends of the bubble. Thus, the channel operates as a passive heat pipe and removes heat from the source by passively circulating the cooling fluid between the vapor bubble and the reservoir(s). |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196838 |
| ART UNIT | 2835 — Electrical Circuits and Systems |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/00 (20130101) F28D 15/0283 (20130101) F28D 2015/0225 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/427 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/20309 (20130101) H05K 7/20318 (20130101) H05K 7/20327 (20130101) H05K 7/20336 (20130101) H05K 7/20936 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 10875284 | Tajvidi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maine System Board of Trustees (Orono, Maine) |
| ASSIGNEE(S) | University of Maine System Board of Trustees (Orono, Maine) |
| INVENTOR(S) | Mehdi Tajvidi (Orono, Maine); Douglas W. Bousfield (Glenburn, Maine) |
| ABSTRACT | Strong, light-weight composite laminates are made by impregnating layers of paper with a cellulose nanofiber (CNF) slurry, laying the coated papers up in a plurality of layers or stack, and subjecting the stack to pressure and heat for a period of time sufficient to cause the CNF to impregnate, reinforce, and bond the paper layers into a composite. The resulting composite has impressive mechanical strength and exhibits a substantially homogeneous composition throughout its depth. The composite should have good strength to weight properties, and be recyclable or compostable. |
| FILED | Thursday, September 08, 2016 |
| APPL NO | 15/260096 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 7/04 (20130101) B32B 29/005 (20130101) Original (OR) Class B32B 38/08 (20130101) B32B 2250/05 (20130101) B32B 2250/26 (20130101) B32B 2260/04 (20130101) B32B 2260/023 (20130101) B32B 2260/028 (20130101) B32B 2262/062 (20130101) B32B 2307/54 (20130101) B32B 2307/546 (20130101) B32B 2307/7163 (20130101) B32B 2317/12 (20130101) B32B 2419/00 (20130101) B32B 2553/00 (20130101) B32B 2605/08 (20130101) B32B 2607/00 (20130101) Pulp Compositions; Preparation Thereof Not Covered by Subclasses D21C or D21D; Impregnating or Coating of Paper; Treatment of Finished Paper Not Covered by Class B31 or Subclass D21G; Paper Not Otherwise Provided for D21H 11/18 (20130101) D21H 17/25 (20130101) D21H 19/34 (20130101) D21H 27/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10875339 | Claussen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Jonathan Claussen (Ames, Iowa); John Hondred (Ames, Iowa); Loreen Stromberg (Ames, Iowa) |
| ABSTRACT | Methods, systems, and compositions to produce high resolution, highly scalable patterns on a variety of substrates. A high resolution sacrificial negative of the desired pattern in inkjet printed on the substrate with an inkjet printable ink. A viscous solution is coated or deposited over the negative pattern and substrate. The solution is stabilized such as by drying and adheres to the substrate. The sacrificial negative is removed, leaving the dried solution in the high resolution form factor defined by the removed negative. This allows the solution to be formulated without regard to meeting inkjet printing requirements but results in a high resolution final positive pattern on the substrate. |
| FILED | Thursday, September 13, 2018 |
| APPL NO | 16/130601 |
| ART UNIT | 1713 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 11/0015 (20130101) Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 5/0017 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/32 (20130101) C09D 11/38 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/168 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/32 (20130101) H01L 21/283 (20130101) H01L 21/288 (20130101) H01L 21/30604 (20130101) H01L 21/32051 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US PP32706 | Trigiano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Knoxville, Tennessee) |
| INVENTOR(S) | Robert N. Trigiano (Knoxville, Tennessee); Sarah Lynn Boggess (Knoxville, Tennessee) |
| ABSTRACT | A new and distinct cultivar of flowering dogwood tree, which has fused bracts is provided. This dogwood tree is botanically known as Cornus kousa and referred to by the following cultivar name: ‘Melissa's Mountain Snowfall’. |
| FILED | Thursday, August 15, 2019 |
| APPL NO | 16/602154 |
| ART UNIT | 1661 — Plants |
| CURRENT CPC | New Plants or Processes for Obtaining Them; Plant Reproduction by Tissue Culture Techniques A01H 5/02 (20130101) Original (OR) Class A01H 5/04 (20130101) A01H 6/00 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 10876024 | Hung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Ching-Cheh Hung (Westlake, Ohio); Janet B. Hurst (Columbia Station, Ohio) |
| ABSTRACT | A material that facilitates dissipation of heat is provided and includes hexagonal boron nitride and alumina. |
| FILED | Wednesday, October 04, 2017 |
| APPL NO | 15/724849 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 21/0648 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/82 (20130101) C01P 2004/03 (20130101) C01P 2004/04 (20130101) C01P 2004/80 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/583 (20130101) C04B 35/645 (20130101) C04B 35/6264 (20130101) C04B 35/6281 (20130101) C04B 35/62675 (20130101) C04B 35/62805 (20130101) C04B 35/62807 (20130101) C04B 35/62813 (20130101) C04B 35/62818 (20130101) C04B 35/62821 (20130101) C04B 35/62823 (20130101) C04B 35/62826 (20130101) C04B 35/62852 (20130101) C04B 35/62897 (20130101) C04B 2235/36 (20130101) C04B 2235/77 (20130101) C04B 2235/386 (20130101) C04B 2235/444 (20130101) C04B 2235/445 (20130101) C04B 2235/656 (20130101) C04B 2235/3215 (20130101) C04B 2235/3217 (20130101) C04B 2235/3236 (20130101) C04B 2235/3272 (20130101) C04B 2235/3409 (20130101) C04B 2235/5252 (20130101) C04B 2235/5284 (20130101) C04B 2235/6562 (20130101) C04B 2235/6565 (20130101) C04B 2235/6583 (20130101) C04B 2235/9607 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/14 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 37/025 (20130101) H01L 41/183 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876276 | Greer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); PWIL Inc. (Flintridge, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); PWIL INC. (Flintridge, California) |
| INVENTOR(S) | Harold Frank Greer (Los Angeles, California); Peter Capak (Pasadena, California); Aria Anvar (Flintridge, California) |
| ABSTRACT | An atmospheric water generation system with high efficiency is based on a counter flowing heat exchanger including multiple cold channels, each cold channel surrounded by multiple hot channels. The hot and warm gases flow in opposite directions, allowing the cool dry air to contribute to cooling the warm humid air to the dew point. Thermoelectric or passive cooling of the warm humid air, and hydrophobic surfaces in a cyclone structure also contribute in increasing the efficiency of the water generation system. |
| FILED | Friday, June 15, 2018 |
| APPL NO | 16/010326 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Separation B01D 5/0006 (20130101) B01D 5/0021 (20130101) B01D 53/002 (20130101) B01D 53/265 (20130101) Installations or Methods for Obtaining, Collecting, or Distributing Water E03B 3/28 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876797 | Townsend et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Craig Technical Consulting, Inc. (Merritt Island, Florida) |
| ASSIGNEE(S) | Craig Technical Consulting, Inc. (Merritt Island, Florida) |
| INVENTOR(S) | Ivan Townsend (Kennedy Space Center, Florida); Philip Metzger (Kennedy Space Center, Florida); Robert Mueller (Kennedy Space Center, Florida); Jason Menzies (Kennedy Space Center, Florida); James Mantovani (Kennedy Space Center, Florida) |
| ABSTRACT | A system for heat transfer including a compressor, a regolith inlet, a first storage hopper, and a load. The compressor is in fluid communication with a closed loop system. The regolith inlet is in fluid communication with the closed loop system. The first storage hopper is adapted to carry an amount of regolith and is in fluid communication with the regolith inlet. The load is in fluid communication with the closed loop system between a compressor inlet a compressor outlet. |
| FILED | Monday, April 08, 2019 |
| APPL NO | 16/377963 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 15/00 (20130101) Original (OR) Class F28D 2021/0021 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 10875839 | Zhao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Crinetics Pharmaceuticals, Inc. (San Diego, California) |
| ASSIGNEE(S) | CRINETICS PHARMACEUTICALS, INC. (San Diego, California) |
| INVENTOR(S) | Jian Zhao (San Diego, California); Shimiao Wang (San Diego, California); Yunfei Zhu (San Diego, California) |
| ABSTRACT | Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity. |
| FILED | Thursday, December 12, 2019 |
| APPL NO | 16/712620 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 401/04 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 405/14 (20130101) C07D 413/14 (20130101) C07D 471/04 (20130101) C07D 498/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10877300 | Coolbaugh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York); Government of the United States, as Represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio); Morton Photonics Incorporated (West Friendship, Maryland) |
| ASSIGNEE(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York); GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (Wright-Patterson AFB, Ohio); MORTON PHOTONICS INCORPORATED (West Friendship, Maryland) |
| INVENTOR(S) | Douglas Coolbaugh (Mechanicville, New York); Douglas La Tulipe (Guilderland, New York); Paul A. Morton (West Friendship, Maryland); Nicholas G. Usechak (Oakwood, Ohio) |
| ABSTRACT | There is set forth herein an integrated photonics structure having a waveguide disposed within a dielectric stack of the integrated photonics structure, wherein the integrated photonics structure further includes a field generating electrically conductive structure disposed within the dielectric stack; and a heterogenous structure attached to the integrated photonics structure, the heterogenous structure having field sensitive material that is sensitive to a field generated by the field generating electrically conductive structure. There is set forth herein a method including fabricating an integrated photonics structure, wherein the fabricating an integrated photonics structure includes fabricating a waveguide within a dielectric stack, wherein the fabricating an integrated photonics structure further includes fabricating a field generating electrically conductive structure within the dielectric stack; and attaching a heterogenous structure to the integrated photonics structure, the heterogenous structure having field sensitive material that is sensitive to a field generated by the field generating electrically conductive structure. |
| FILED | Wednesday, April 03, 2019 |
| APPL NO | 16/374341 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/12 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/035 (20130101) Original (OR) Class G02F 1/095 (20130101) G02F 1/0955 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879671 | Deppe |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | sdPhotonics LLC (Richardson, Texas) |
| ASSIGNEE(S) | sdPhotonics LLC (Richardson, Texas) |
| INVENTOR(S) | Dennis G. Deppe (Richardson, Texas) |
| ABSTRACT | A semiconductor vertical resonant cavity light source includes an upper and lower mirror that define a vertical resonant cavity. An active region is within the cavity for light generation between the upper and lower mirror. At least one cavity spacer region is between the active region and the upper mirror or lower mirror. The cavity includes an inner mode confinement region and an outer current blocking region. An index guide in the inner mode confinement region is between the cavity spacer region and the upper or lower mirror. The index guide and outer current blocking region each include a lower and upper epitaxial material layer thereon with an epitaxial interface region in between. At least a top surface of the lower material layer includes aluminum in the interface region throughout a full area of an active part of the vertical light source. |
| FILED | Friday, August 09, 2019 |
| APPL NO | 16/537139 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/183 (20130101) H01S 5/187 (20130101) H01S 5/1833 (20130101) H01S 5/2018 (20130101) H01S 5/2059 (20130101) H01S 5/2072 (20130101) H01S 5/18308 (20130101) H01S 5/18327 (20130101) H01S 5/18333 (20130101) Original (OR) Class H01S 5/18358 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 10876145 | Ensor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Triangle Institute (Research Triangle Park, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David S. Ensor (Chapel Hill, North Carolina); Howard Jerome Walls (Apex, North Carolina); Karin K. Foarde (Chapel Hill, North Carolina); Susanne Vera Hering (Berkeley, California); Steven Russel Spielman (Berkeley, California) |
| ABSTRACT | An aerosol collection system and method. The system includes a bio-aerosol delivery device configured to supply bioparticles in a gas stream, a moisture exchange device including a partition member coupled to the gas stream and configured to humidify or dehumidify the bioparticles in the gas stream, and an aerosol collection medium downstream from the moisture exchange device and configured to collect the bioparticles. The method includes delivering bioparticles in a gas stream, humidifying or dehumidifying the bioparticles in the gas stream by transport of water across a partition member and into a vapor phase of the gas stream, and collecting the bioparticles by a collection medium. |
| FILED | Wednesday, May 27, 2020 |
| APPL NO | 16/884764 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10876901 | Srinivas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TDA Research, Inc (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | TDA Research, Inc (Wheat Ridge, Colorado) |
| INVENTOR(S) | Girish Srinivas (Broomfield, Colorado); Michael Karpuk (Boulder, Colorado); Steven Gebhard (Golden, Colorado); Joe Fredrickson (Brighton, Colorado); Andrew D. Galloway (Wheat Ridge, Colorado) |
| ABSTRACT | A decoupling radiant and convective heat sensing device having sensor elements facing in different directions, and a decoupling radiant and convective heat sensing device having sensor elements facing in different directions with a means for determining the remaining time before a Self Contained Breathing Apparatus facemask will become compromised by dangerous heat conditions. |
| FILED | Monday, August 28, 2017 |
| APPL NO | 15/688525 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 9/006 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/04 (20130101) G01J 5/12 (20130101) G01J 5/0018 (20130101) G01J 5/025 (20130101) G01J 5/0215 (20130101) G01J 5/0265 (20130101) G01J 5/0853 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 7/02 (20130101) Original (OR) Class G01K 7/427 (20130101) G01K 17/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 10874646 | Nicolaou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Kyriacos C Nicolaou (Houston, Texas); Derek Rhoades (Houston, Texas); Yanping Wang (Houston, Texas); Sotirios Totokotsopoulos (Chicago, Illinois) |
| ABSTRACT | In one aspect, the present disclosure provides epothilone analogs of the formula (I) wherein the variables are as defined herein. In another aspect, the present disclosure also provides methods of preparing the compounds disclosed herein. In another aspect, the present disclosure also provides pharmaceutical compositions and methods of use of the compounds disclosed herein. Additionally, drug conjugates with cell targeting moieties of the compounds are also provided. |
| FILED | Friday, October 14, 2016 |
| APPL NO | 15/768800 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/427 (20130101) Original (OR) Class A61K 31/427 (20130101) A61K 31/428 (20130101) A61K 31/428 (20130101) A61K 31/4155 (20130101) A61K 31/4155 (20130101) A61K 31/4427 (20130101) A61K 31/4427 (20130101) A61K 39/395 (20130101) A61K 45/06 (20130101) A61K 47/6869 (20170801) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Heterocyclic Compounds C07D 405/06 (20130101) C07D 407/06 (20130101) C07D 491/08 (20130101) C07D 493/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 10879839 | Ayyanar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Rajapandian Ayyanar (Gilbert, Arizona); Yinglai Xia (Tempe, Arizona); Jinia Roy (Tempe, Arizona) |
| ABSTRACT | Power converter circuitry includes a direct current (DC) input comprising a first DC input node and a second DC input node, an alternating current (AC) output comprising a first AC output node coupled to the first DC input node and a second AC output node, a first boost switch coupled between the second DC input node and a boost intermediate node, a second boost switch coupled between the boost intermediate node and a common node, a boost inductor coupled between the boost intermediate node and the first DC input node, a link capacitor coupled between the second DC input node and the common node, a first half-bridge switch coupled between the second DC input node and a half-bridge intermediate node, a second half-bridge switch coupled between the half-bridge intermediate node and the common node, and a half-bridge inductor coupled between the half-bridge intermediate node and the second AC output node. |
| FILED | Monday, December 05, 2016 |
| APPL NO | 15/780840 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/383 (20130101) Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 3/158 (20130101) H02M 3/1582 (20130101) H02M 7/487 (20130101) H02M 7/537 (20130101) H02M 7/4826 (20130101) H02M 7/5387 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/32 (20141201) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Central Intelligence Agency (CIA)
| US 10877948 | Beskales et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tamr, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | TAMR, INC. (Cambridge, Massachusetts) |
| INVENTOR(S) | George Anwar Dany Beskales (Waltham, Massachusetts); Nikolaus Bates-Haus (Littleton, Massachusetts) |
| ABSTRACT | Given a local distance metric for geospatial features, a binning is produced that is guaranteed to label features within a given distance threshold with the same bin, while labeling a minimum number of features separated by a distance that is greater than the threshold with the same bin. |
| FILED | Wednesday, July 01, 2020 |
| APPL NO | 16/918158 |
| ART UNIT | 2158 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/29 (20190101) G06F 16/215 (20190101) Original (OR) Class G06F 16/285 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 10878281 | Cheng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Yu Cheng (Ossining, New York); Sharathchandra U. Pankanti (Darien, Connecticut); Nalini K. Ratha (White Plains, New York) |
| ABSTRACT | A face clustering system for video face clustering in a video sequence, the system including an inherent supervision summarization device configured to collect group-level supervision and instance level supervision within a same chunklet based on a user input of face images for a person, a discriminative projection learning device configured to embed group constraints of the group-level supervision into a transformed space, and configured to generate an embedding space from the original image feature space, and a clustering device, in the embedding space, configured to execute pair-wise based clustering to cluster the video images into different clusters with the instance level supervision collected by the inherent supervision summarization device. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/587134 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00288 (20130101) G06K 9/00295 (20130101) G06K 9/00718 (20130101) G06K 9/6218 (20130101) Original (OR) Class G06K 9/6264 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 10875248 | Afshar Mohajer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS (Fayetteville, Arkansas) |
| ASSIGNEE(S) | Board Of Trustees Of The University Of Arkansas (Fayetteville, Arkansas) |
| INVENTOR(S) | Mahyar Afshar Mohajer (Fayetteville, Arkansas); Josue Goss (Fayetteville, Arkansas); Dipankar Choudhury (Fayetteville, Arkansas); Min Zou (Fayetteville, Arkansas); Shelby Robert Maddox (Fayetteville, Arkansas) |
| ABSTRACT | The present invention relates generally to methods of fabricating surface topography based on a scanned surface topography. The method converts 3D scanned surface topography data that have submicron resolution to digital formats that can be stored, manipulated, or tiled, and used as an input for replicating the surface topography with submicron resolution on another substrate. The digitized surface topography data is then converted to input for 1) 3D printing to replicate the scanned surface topography with submicron resolution, with or without a subsequent coating layer or layers to impart additional properties and/or features, 2) 3D printing a master that replicates the scanned surface topography with submicron resolution, which will be used for fast replica molding of the surface topography onto another substrate, and 3) creating a photomask with submicron resolution for transferring the surface topography to a metal substrate surface through subsequent photolithography and etching processes. |
| FILED | Monday, February 11, 2019 |
| APPL NO | 16/273103 |
| ART UNIT | 1716 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/30 (20170801) Original (OR) Class B29C 64/393 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/00 (20141201) B33Y 50/02 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 10875637 | Podgurski |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Daniel M. Podgurski (West Chester, Pennsylvania) |
| ABSTRACT | Rotor assembly apparatus are disclosed. An example rotor assembly includes a twist actuator to drive a first rotation of a first shaft about a first axis, the twist actuator positioned at a center of rotation of the rotor assembly. A first gear assembly to convert the first rotation into a plurality of second rotations of a plurality of second shafts. Each of the second shafts to provide torque to a respective blade coupled to the rotor assembly. |
| FILED | Thursday, May 10, 2018 |
| APPL NO | 15/976582 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/37 (20130101) Original (OR) Class B64C 27/59 (20130101) B64C 27/72 (20130101) B64C 27/605 (20130101) B64C 2027/004 (20130101) B64C 2027/7222 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 7/00 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/72 (20130101) F05D 2260/76 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 50/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 29, 2020.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2020/fedinvent-patents-20201229.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page