FedInvent™ Patents
Patent Details for Tuesday, September 21, 2021
This page was updated on Wednesday, September 22, 2021 at 04:37 PM GMT
Department of Health and Human Services (HHS)
| US 11122784 | Bolotina |
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| FUNDED BY |
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| APPLICANT(S) | Boston Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Boston Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Victoria Bolotina (North Andover, Massachusetts) |
| ABSTRACT | This application provides a novel mouse model (PLA2g6 KOEx2) in which genetic deletion of the N terminus of PLA2g6 results in a loss of dopaminergic (DA) neurons in substantia nigra (SN), and development of PD-like motor deficits that can be significantly improved by L-DOPA. Based in part on experimental results demonstrated with this model, this disclosure provides genetically modified animals and genetically modified animal cells that comprise a mutant allele of PLA2g6 and in which store-operated Ca2+ entry (SOCE) is impaired and ER Ca2+ stores are depleted. This disclosure also provides methods of screening a compound for an effect on the SOCE pathway and/or ER Ca2+ by administering the compound to such a genetically modified animal or genetically modified animal cell. This disclosure also provides methods of treating or preventing PD-related deficit(s) in an animal by characterizing a compound as a SOCE activator using the screening methods and then administering an effective amount of the compound to an animal. This disclosure also provides methods of restoring normal store-operated Ca2+ entry (SOCE) pathway and ER Ca2+ in a cell, comprising introducing a caspase-3 cleavage-resistant PLA2g6 protein into the cell. This disclosure also provides methods of treating or preventing a PD-related deficit(s) in an animal, comprising administering a caspase-3 cleavage-resistant PLA2g6 protein to the animal. |
| FILED | Wednesday, July 31, 2019 |
| APPL NO | 16/527446 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0276 (20130101) Original (OR) Class A01K 2217/056 (20130101) A01K 2217/075 (20130101) A01K 2227/105 (20130101) A01K 2267/0318 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/465 (20130101) A61K 48/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 9/18 (20130101) C12N 9/20 (20130101) C12N 2510/00 (20130101) Enzymes C12Y 301/01004 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) G01N 33/5091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11122965 | Valdastri et al. |
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| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Pietro Valdastri (Leeds, United Kingdom); Piotr R. Slawinski (Lincoln, Nebraska); Addisu Z. Taddese (Nashville, Tennessee); Keith L. Obstein (Nashville, Tennessee) |
| ABSTRACT | Systems and methods are presented for localization of a capsule based on magnetic fields. The capsule is positioned in a magnetic field generated by a first magnet and an electromagnetic coil is operated to generate a sinusoidal magnetic field with a magnetic moment orthogonal to the magnetic moment of the first magnet. An average signal measurement calculated for each magnetic field sensor is defined as the magnetic field applied to the magnetic field sensor by the first magnet and used as an offset to determine the magnetic field applied by the electromagnetic coil. The pose of the capsule is then determined based at least in part on a combination of magnetic field signals applied by the electromagnetic coil to each of the magnetic field sensors. |
| FILED | Tuesday, October 09, 2018 |
| APPL NO | 16/155637 |
| ART UNIT | 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/0008 (20130101) A61B 1/018 (20130101) A61B 1/041 (20130101) A61B 1/00149 (20130101) A61B 1/00158 (20130101) Original (OR) Class A61B 5/062 (20130101) A61B 5/6861 (20130101) A61B 34/73 (20160201) A61B 2034/731 (20160201) A61B 2034/2048 (20160201) A61B 2034/2051 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11122981 | Olender et al. |
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| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSEHIS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Max Louis Olender (Cambridge, Massachusetts); Lambros Athanasiou (Medford, Massachusetts); Elazer R. Edelman (Brookline, Massachusetts) |
| ABSTRACT | A method, including: obtaining, by a processor, imaging data from a vessel; detecting, using the processor, an inner wall of the vessel based on the imaging data; identifying, using the processor, a plurality of visible edge portions of an outer wall of the vessel based on the imaging data; fitting, using the processor, a continuous surface model to the plurality of identified visible edge portions of the outer wall; and detecting, using the processor, the outer wall of the vessel based on fitting the continuous surface model to the plurality of identified visible edge portions of the outer wall such that the imaging data has defined therein a wall area between the inner wall and the outer wall of the vessel. |
| FILED | Friday, May 17, 2019 |
| APPL NO | 16/415430 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0035 (20130101) A61B 5/0066 (20130101) A61B 5/0084 (20130101) A61B 5/02007 (20130101) Original (OR) Class A61B 5/6852 (20130101) A61B 8/12 (20130101) Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 9/02091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11122982 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Joseph Wang (San Diego, California); Patrick Mercier (San Diego, California) |
| ABSTRACT | Methods, systems, and devices are disclosed for wearable, real-time multimodal sensing of electrochemical and electrophysiological and/or physical parameters of a user. In some aspects, a multimodal sensor device includes a flexible substrate; an electrochemical sensor disposed on the substrate and including electrochemical sensing electrodes operable to measure an electrical signal corresponding to a reaction including a chemical substance via an electrochemical sensing electrode and an analyte at the electrochemical sensor; and an electrophysiological sensor including two or more electrodes disposed on the substrate to acquire an electrophysiological signal of the user, such that when the multimodal sensor device is electrically coupled to an electronics unit and adhered to the user, the device is operable to simultaneously monitor an electrochemical parameter and an electrophysiological parameter of the user. |
| FILED | Monday, April 03, 2017 |
| APPL NO | 16/090083 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/053 (20130101) A61B 5/0205 (20130101) Original (OR) Class A61B 5/259 (20210101) A61B 5/282 (20210101) A61B 5/318 (20210101) A61B 5/0816 (20130101) A61B 5/1468 (20130101) A61B 5/1486 (20130101) A61B 5/02055 (20130101) A61B 5/6833 (20130101) A61B 5/14532 (20130101) A61B 2562/066 (20130101) A61B 2562/164 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11122997 | Ray et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); Ixcela Inc. (Bedford, Massachusetts); Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota); Ixcela Inc. (Bedford, Massachusetts); Duke University (Durham, North Carolina) |
| INVENTOR(S) | Balmiki Ray (Rochester, Minnesota); Liewei Wang (Rochester, Minnesota); Joanna Biernacka (Rochester, Minnesota); Mark Frye (Rochester, Minnesota); Richard M. Weinshilboum (Rochester, Minnesota); Michiaki Kubo (Kanagawa, Japan); Taisei Mushiroda (Kawaguchi, Japan); Wayne R. Matson (Ayer, Massachusetts); Rima Kaddurah-Daouk (Belmont, Massachusetts) |
| ABSTRACT | Materials and methods for treating major depressive disorder by modulating the aryl hydrocarbon receptor system are provided herein. |
| FILED | Friday, April 15, 2016 |
| APPL NO | 15/567176 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) A61B 5/4839 (20130101) A61B 5/14546 (20130101) Original (OR) Class Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/05 (20130101) A61K 31/12 (20130101) A61K 31/015 (20130101) A61K 31/352 (20130101) A61K 31/404 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6872 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123048 | Bhuyan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Anshuman Bhuyan (Milpitas, California); Jung Woo Choe (Sunnyvale, California); Amin Nikoozadeh (Palo Alto, California); Butrus T. Khuri-Yakub (Palo Alto, California) |
| ABSTRACT | Ultrasound imaging and therapy with the same array of capacitive micromachined ultrasonic transducers is provided. The electronics includes a per-pixel switch for each transducer element. The switches provide an imaging mode driven completely by on-chip electronics and a therapy mode where off-chip pulsers provide relatively high voltages to the transducer elements. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/150044 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/54 (20130101) Original (OR) Class A61B 8/4483 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) A61N 7/02 (20130101) A61N 2007/0021 (20130101) A61N 2007/0052 (20130101) Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0215 (20130101) B06B 1/0292 (20130101) B06B 2201/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123128 | You et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Joon S You (Laguna Niguel, California); Brian Jet-Fei Wong (Irvine, California); Wesley Moy (Irvine, California) |
| ABSTRACT | A method of altering skin tissue includes creating an electrochemical reaction in the tissue, wherein the electrochemical reaction occurs while avoiding electro-thermal damage to the tissue. |
| FILED | Wednesday, February 21, 2018 |
| APPL NO | 15/900985 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/02 (20130101) A61B 18/00 (20130101) A61B 18/1206 (20130101) Original (OR) Class A61B 18/1477 (20130101) A61B 2018/0072 (20130101) A61B 2018/00452 (20130101) A61B 2018/00565 (20130101) A61B 2018/00714 (20130101) A61B 2018/00761 (20130101) A61B 2018/00827 (20130101) A61B 2018/00892 (20130101) A61B 2018/1425 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/328 (20130101) A61N 1/0502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123141 | Belohlavek et al. |
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| FUNDED BY |
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| APPLICANT(S) | MAYO Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Marek Belohlavek (Scottsdale, Arizona); Eileen M. McMahon (Cocoa, Florida) |
| ABSTRACT | Systems and methods for navigating a catheter and delivering a needle to a desired anatomic location are provided. The system includes an injection catheter that includes a needle slidably exposed from, or retracted into, the catheter lumen. The system further includes a first acoustic marker located at a distal end of the catheter and configured to generate an acoustic signal, and a second acoustic marker located at the distal end of the retractable needle and configured to generate an acoustic signal. The acoustic markers allow, in conjunction with a Doppler ultrasound imaging system, identification and navigation of an injection catheter and delivering a needle to a desired anatomic target location. |
| FILED | Friday, April 22, 2016 |
| APPL NO | 15/136064 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/12 (20130101) A61B 8/461 (20130101) A61B 8/488 (20130101) A61B 8/0841 (20130101) A61B 8/0883 (20130101) A61B 34/20 (20160201) Original (OR) Class A61B 2034/2063 (20160201) A61B 2090/3929 (20160201) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/158 (20130101) A61M 25/0084 (20130101) A61M 25/0108 (20130101) A61M 2005/1588 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123302 | Dayton et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); The Arizona Board of Regents on behalf of The University of Arizona (Tucson, Arizona); The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, North Carolina); THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona); THE REGENTS OF THE UNIVERSITY OF COLORADO (Denver, Colorado) |
| INVENTOR(S) | Paul A. Dayton (Carrboro, North Carolina); Paul S. Sheeran (Durham, North Carolina); Terry O. Matsunaga (Tucson, Arizona); Mark A. Borden (Boulder, Colorado) |
| ABSTRACT | Acoustically activatable particles having low vaporization energy are disclosed. A particle of material includes a first substance that includes at least one component that has a boiling point below 25° C. at atmospheric pressure. A second substance, different from the first substance, encapsulates the first substance to create the particle. The particle has a core consisting of a liquid and is an activatable phase change agent. The second substance includes a polymeric brush layer to prevent aggregation and coalescence. |
| FILED | Thursday, August 25, 2016 |
| APPL NO | 15/247840 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/51 (20130101) Original (OR) Class A61K 9/5123 (20130101) A61K 9/5192 (20130101) A61K 41/0028 (20130101) A61K 47/06 (20130101) A61K 48/00 (20130101) A61K 49/0002 (20130101) A61K 49/221 (20130101) A61K 49/223 (20130101) A61K 49/226 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123304 | Farokhzad et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Omid C. Farokhzad (Waban, Massachusetts); Jun Wu (Boston, Massachusetts); Xi Zhu (Qingdao, China PRC); Jinjun Shi (Boston, Massachusetts) |
| ABSTRACT | This disclosure relates to nanoparticles comprising a core comprising a poly(ester amide) polymer comprising a repeating unit of Formula (Ia): and a repeating unit of Formula (Ib): wherein W1, W2, X1, A1, X2, A2, and X3 are as described herein, a payload molecule within the core, and a surface layer comprising a targeting ligand that binds or reacts selectively with a receptor on the outside surface of a cell. Methods of making such nanoparticles, and methods of using such nanoparticles as drug delivery vehicles, are also provided. |
| FILED | Friday, February 03, 2017 |
| APPL NO | 16/483170 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5153 (20130101) Original (OR) Class A61K 9/5192 (20130101) A61K 31/337 (20130101) A61K 38/28 (20130101) A61K 39/35 (20130101) A61K 2039/55516 (20130101) A61K 2039/55544 (20130101) A61K 2039/55561 (20130101) A61K 2039/55572 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123311 | Hammock et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Bruce D. Hammock (Davis, California); Christophe Morisseau (West Sacramento, California); Jun Yang (Davis, California); Kenji Hashimoto (Chiba, Japan) |
| ABSTRACT | This invention provides methods for preventing, mitigating, ameliorating and/or controlling psychiatric disorders, including depression, major depression, bipolar disorder, schizophrenia and substance abuse (including addiction and dependence) by administration of an agent that increases epoxy-fatty acids (e.g., an inhibitor of soluble epoxide hydrolase), as sole active agent or in combination with another agent (e.g., an antidepressant, an antipsychotic, an anxiolytic). When co-administered in combination with another agent, one or both agent may be administered at a subtherapeutic dose. |
| FILED | Thursday, December 15, 2016 |
| APPL NO | 16/065907 |
| ART UNIT | 1699 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/15 (20130101) A61K 31/135 (20130101) A61K 31/137 (20130101) Original (OR) Class A61K 31/138 (20130101) A61K 31/165 (20130101) A61K 31/185 (20130101) A61K 31/336 (20130101) A61K 31/343 (20130101) A61K 31/352 (20130101) A61K 31/381 (20130101) A61K 31/4525 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/18 (20180101) A61P 25/24 (20180101) A61P 25/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123312 | Lu et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Daniel C. Lu (Los Angeles, California); V. Reggie Edgerton (Los Angeles, California); Roland R. Roy (Playa Vista, California); Yury P. Gerasimenko (Los Angeles, California) |
| ABSTRACT | In various embodiments, methods are provided for applying transcutaneous and/or epidural spinal cord stimulation with and without selective pharmaceuticals to restore voluntary control of hand function in tetraplegic subjects. |
| FILED | Monday, November 26, 2018 |
| APPL NO | 16/200467 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) Original (OR) Class A61K 31/496 (20130101) A61K 31/506 (20130101) A61K 31/517 (20130101) A61K 31/527 (20130101) A61K 31/4168 (20130101) A61K 31/4178 (20130101) A61K 31/4985 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0551 (20130101) A61N 1/36003 (20130101) A61N 1/36034 (20170801) A61N 1/36067 (20130101) A61N 1/36171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123313 | Wellman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | D. Andrew Wellman (Wayland, Massachusetts); Luigi Taranto-Montemurro (Chestnut Hill, Massachusetts) |
| ABSTRACT | Methods and compositions for the treatment of conditions associated with pharyngeal airway muscle collapse while the subject is in a non-fully conscious state, e.g., sleep apnea and snoring, comprising administration of a norepinephrine reuptake inhibitor (NRI) and a muscarinic receptor antagonist. |
| FILED | Thursday, April 26, 2018 |
| APPL NO | 16/609048 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/137 (20130101) Original (OR) Class A61K 31/216 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123333 | Xie et al. |
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| FUNDED BY |
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| APPLICANT(S) | Meharry Medical College (Nashville, Tennessee); Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Meharry Medical College (Nashville, Tennessee); Duke University (Durham, North Carolina) |
| INVENTOR(S) | Hua Xie (Nashville, Tennessee); Chin-Ho Chen (Durham, North Carolina) |
| ABSTRACT | The disclosure provides compounds that inhibit the invasion of host cells by intracellular parasites. These find use, for example, in treating and preventing periodontitis or a periodontitis-related condition or symptom. |
| FILED | Sunday, February 17, 2019 |
| APPL NO | 16/278126 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/042 (20130101) A61K 8/42 (20130101) A61K 8/0204 (20130101) A61K 8/4926 (20130101) A61K 31/166 (20130101) A61K 31/439 (20130101) Original (OR) Class A61K 31/4748 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/02 (20180101) A61P 31/04 (20180101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 11/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5044 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123334 | Woods et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board Of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | James H. Woods (San Antonio, Texas); Charles Patrick France (San Antonio, Texas) |
| ABSTRACT | The disclosure relates to compositions and methods of preventing or treating a subject suffering from opioid toxicity or overdose. The method comprises administering to a patient in need of treatment an effective amount of methocinnamox. |
| FILED | Friday, March 22, 2019 |
| APPL NO | 16/361426 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/439 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/36 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123340 | Verkman et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Alan S. Verkman (San Francisco, California); Cristina Esteva-Font (San Francisco, California) |
| ABSTRACT | Provided herein are compounds that are urea transporter-A inhibitors that are useful for producing a strong diuretic response and may be used for treating refractory edema associated with cardiovascular, renal, and metabolic diseases, disorders, and conditions. |
| FILED | Wednesday, September 04, 2019 |
| APPL NO | 16/560880 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 31/425 (20130101) A61K 31/426 (20130101) A61K 31/427 (20130101) A61K 31/4709 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123341 | Zhan et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Chang-Guo Zhan (Lexington, Kentucky); Fang Zheng (Lexington, Kentucky) |
| ABSTRACT | A method of treating opioid use disorder involves administering a selective butyrylcholinesterase (BChE) inhibitor. |
| FILED | Tuesday, May 26, 2020 |
| APPL NO | 16/883291 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/36 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123405 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Seulki Lee (Elkridge, Maryland); Ted M. Dawson (Baltimore, Maryland); Han Seok Ko (Lutherville Timonium, Maryland); Valina L. Dawson (Baltimore, Maryland); Seung Pil Yun (Lutherville Timonium, Maryland); Magdalena Scully (Columbia, Maryland) |
| ABSTRACT | The present invention relates to compositions and methods for treating neurodegenerative conditions using GLP-1r agonists. In certain embodiments, long-acting GLP-1r agonists have neuroprotective and disease modifying effects on the central nervous system. |
| FILED | Thursday, December 22, 2016 |
| APPL NO | 16/065445 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/26 (20130101) Original (OR) Class A61K 38/38 (20130101) A61K 47/60 (20170801) A61K 47/68 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123416 | Pier et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Gerald B. Pier (Brookline, Massachusetts); Nikolay Nifantiev (Moscow, Russian Federation); Yury Tsvetkov (Moscow, Russian Federation); Marina Gening (Moscow, Russian Federation) |
| ABSTRACT | The invention relates to the compositions of synthetic oligo-β-(1→6)-2-amino-2-deoxy-D-glu-copyranosides conjugated to carriers, and methods for making and use same. |
| FILED | Friday, June 22, 2018 |
| APPL NO | 16/016473 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/085 (20130101) Original (OR) Class A61K 47/646 (20170801) A61K 47/6415 (20170801) A61K 2039/55 (20130101) A61K 2039/552 (20130101) A61K 2039/575 (20130101) A61K 2039/6037 (20130101) Acyclic or Carbocyclic Compounds C07C 327/32 (20130101) Heterocyclic Compounds C07D 207/46 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 3/06 (20130101) Peptides C07K 16/1232 (20130101) C07K 16/1271 (20130101) C07K 2317/33 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123423 | Whelan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Sean P. J. Whelan (Cambridge, Massachusetts); Sayantan Bose (Brookline, Massachusetts); Joseph Timpona (Roxbury Crossing, Massachusetts) |
| ABSTRACT | Compositions and methods useful for treating and/or preventing a Zika virus infection are provided. |
| FILED | Thursday, October 19, 2017 |
| APPL NO | 16/343113 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/205 (20130101) Original (OR) Class A61K 2039/5256 (20130101) A61K 2039/5258 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/20021 (20130101) C12N 2760/20223 (20130101) C12N 2760/20234 (20130101) C12N 2760/20241 (20130101) C12N 2760/20243 (20130101) C12N 2770/24121 (20130101) C12N 2770/24134 (20130101) C12N 2770/24171 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123440 | Tsourkas et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Andrew Tsourkas (Bryn Mawr, Pennsylvania); James Z. Hui (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention relates to antibody conjugates (e.g., a bispecific antibody), drug and nanoparticle compositions and methods and compositions for generating them. This invention further relates to methods of using these compositions for imaging, diagnosing or treating a disease. |
| FILED | Thursday, May 12, 2016 |
| APPL NO | 15/573757 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6851 (20170801) A61K 47/6889 (20170801) Original (OR) Class A61K 2039/572 (20130101) Peptides C07K 14/315 (20130101) C07K 16/468 (20130101) C07K 16/2803 (20130101) C07K 16/2809 (20130101) C07K 16/2887 (20130101) C07K 2317/31 (20130101) C07K 2317/52 (20130101) C07K 2317/73 (20130101) C07K 2317/92 (20130101) C07K 2317/622 (20130101) C07K 2319/20 (20130101) C07K 2319/21 (20130101) C07K 2319/30 (20130101) C07K 2319/60 (20130101) C07K 2319/61 (20130101) C07K 2319/70 (20130101) C07K 2319/705 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/48 (20130101) C12N 15/62 (20130101) Enzymes C12Y 304/2207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123441 | Muzykantov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Vladimir Muzykantov (Bryn Athyn, Pennsylvania); Jacob Brenner (Princeton Junction, New York); Jacob Myerson (Clayton, Missouri); Daniel Pan (Philadelphia, Pennsylvania); Samir Suresh Mitragotri (Lexington, Massachusetts) |
| ABSTRACT | Compositions comprising a red blood cell (RBC) having non-toxically coupled thereto a nanoparticle having a low shear modulus or low Young's modulus of less than 10 MPa and containing a drug are provided. In one embodiment, the nanoparticles are optionally coated with protein. In another embodiment, the nanoparticle has no cell-specific targeting moiety or tissue-specific targeting moiety or organ-specific targeting moiety associated therewith. Methods of delivering selected drugs to target organs use these compositions both in vivo and ex vivo treatment of disease and for imaging. |
| FILED | Monday, October 02, 2017 |
| APPL NO | 15/722583 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/137 (20130101) A61K 31/573 (20130101) A61K 38/18 (20130101) A61K 47/61 (20170801) A61K 47/64 (20170801) A61K 47/643 (20170801) A61K 47/6843 (20170801) A61K 47/6849 (20170801) A61K 47/6901 (20170801) Original (OR) Class A61K 47/6903 (20170801) A61K 47/6911 (20170801) A61K 47/6913 (20170801) A61K 47/6935 (20170801) A61K 49/0073 (20130101) A61K 49/0097 (20130101) A61K 51/1203 (20130101) A61K 51/1213 (20130101) A61K 51/1244 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123454 | Jiang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Hongbin Jiang (Export, Pennsylvania); William R. Wagner (Gibsonia, Pennsylvania); Tomo Yoshizumi (Pittsburgh, Pennsylvania); Yang Zhu (Pittsburgh, Pennsylvania) |
| ABSTRACT | Provided are novel biocompatible copolymers, compositions comprising the copolymers, and methods of using the copolymers. The copolymers are non-toxic and typically have an LCST below 37° C. Compositions comprising the copolymers can be used for wound treatment, as a cellular growth matrix or niche and for injection into cardiac tissue to repair and mechanically support damaged tissue. The copolymers comprise numerous ester linkages so that the copolymers are erodeable in situ. Degradation products of the copolymers are soluble and non-toxic. The copolymers can be amine-reactive so that they can conjugate with proteins, such as collagen. Active ingredients, such as drugs, can be incorporated into compositions comprising the copolymers. |
| FILED | Wednesday, February 19, 2020 |
| APPL NO | 16/794796 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0024 (20130101) A61K 47/30 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/16 (20130101) Original (OR) Class A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 2300/414 (20130101) A61L 2400/06 (20130101) A61L 2430/20 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 220/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123485 | Patel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Beta Bionics, Inc. (Concord, Massachusetts) |
| ASSIGNEE(S) | Beta Bionics, Inc. (Concord, Massachusetts) |
| INVENTOR(S) | Himanshu Patel (Rancho Santa Margarita, California); Michael J. Rosinko (Las Vegas, Nevada); Edward R. Damiano (Acton, Massachusetts); David Chi-Wai Lim (Irvine, California); Firas H. El-Khatib (Allston, Massachusetts); John R. Costik (Livonia, New York); Justin P. Brown (Tustin, California); Bryan Dale Knodel (Flagstaff, Arizona) |
| ABSTRACT | Systems and methods are disclosed herein for switching an application executing on an ambulatory medical device to a new application without interrupting therapy provided by the ambulatory medical device to a subject. The ambulatory medical device may receive an indication that an update to an application executing on the ambulatory insulin pump is available, establish a communication connection to a host computing system, download and install the application update, while a prior version of the application continues to run. The disclosed systems and methods can confirm successful installation of the application update on the ambulatory medical device and switch control of the ambulatory medical device from the prior version to the new version of the application without interrupting therapy provided to the subject. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/062361 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/14532 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/172 (20130101) Original (OR) Class A61M 5/1723 (20130101) A61M 5/14244 (20130101) A61M 5/14248 (20130101) A61M 5/16831 (20130101) A61M 2005/1726 (20130101) A61M 2005/14208 (20130101) A61M 2205/18 (20130101) A61M 2205/50 (20130101) A61M 2205/52 (20130101) A61M 2205/502 (20130101) A61M 2205/505 (20130101) A61M 2205/581 (20130101) A61M 2205/582 (20130101) A61M 2205/583 (20130101) A61M 2205/609 (20130101) A61M 2205/3327 (20130101) A61M 2205/3546 (20130101) A61M 2205/3553 (20130101) A61M 2205/3584 (20130101) A61M 2205/3592 (20130101) A61M 2230/201 (20130101) Electric Digital Data Processing G06F 3/04847 (20130101) G06F 3/04883 (20130101) G06F 8/61 (20130101) G06F 8/65 (20130101) G06F 8/656 (20180201) G06F 21/31 (20130101) G06F 21/84 (20130101) G06F 21/305 (20130101) G06F 21/6245 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/18 (20130101) G08B 21/0453 (20130101) G08B 25/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/17 (20180101) G16H 40/00 (20180101) G16H 40/40 (20180101) G16H 40/60 (20180101) G16H 40/67 (20180101) G16H 50/30 (20180101) G16H 80/00 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/30 (20130101) H04L 9/088 (20130101) H04L 63/101 (20130101) H04L 67/34 (20130101) Wireless Communication Networks H04W 76/10 (20180201) H04W 76/14 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11123486 — Switching blood glucose control system execution without interruption of therapy delivery
| US 11123486 | Rosinko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Beta Bionics, Inc. (Concord, Massachusetts) |
| ASSIGNEE(S) | Beta Bionics, Inc. (Concord, Massachusetts) |
| INVENTOR(S) | Michael J. Rosinko (Las Vegas, Nevada); Edward R. Damiano (Acton, Massachusetts); David Chi-Wai Lim (Irvine, California); Firas H. El-Khatib (Allston, Massachusetts); Himanshu Patel (Rancho Santa Margarita, California); John R. Costik (Livonia, New York); Justin P. Brown (Tustin, California); Bryan Dale Knodel (Flagstaff, Arizona) |
| ABSTRACT | Systems and methods are disclosed herein for switching control of an ambulatory medical device from an application executing on the ambulatory medical device to a safe version or a new version of the application without interrupting therapy provided by the ambulatory medical device to a subject. The ambulatory medical device can maintain copies of a safe version and a new version of the application. The disclosed systems and methods can execute the new version, while the prior version of the application continues to execute, determine whether a minimum set of operating conditions are satisfied by the new version, and switch control of the ambulatory medical device from the prior version to the new version. The systems and methods can also automatically revert to the safe version of the application case the current version is malfunctioning without interrupting therapy provided to the subject. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/062377 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/14532 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/142 (20130101) A61M 5/172 (20130101) Original (OR) Class A61M 5/1723 (20130101) A61M 5/14244 (20130101) A61M 5/14248 (20130101) A61M 5/16831 (20130101) A61M 2005/1726 (20130101) A61M 2005/14208 (20130101) A61M 2205/18 (20130101) A61M 2205/50 (20130101) A61M 2205/52 (20130101) A61M 2205/502 (20130101) A61M 2205/505 (20130101) A61M 2205/581 (20130101) A61M 2205/582 (20130101) A61M 2205/583 (20130101) A61M 2205/609 (20130101) A61M 2205/3327 (20130101) A61M 2205/3546 (20130101) A61M 2205/3553 (20130101) A61M 2205/3584 (20130101) A61M 2205/3592 (20130101) A61M 2230/201 (20130101) Electric Digital Data Processing G06F 3/04847 (20130101) G06F 3/04883 (20130101) G06F 8/61 (20130101) G06F 8/65 (20130101) G06F 8/656 (20180201) G06F 21/31 (20130101) G06F 21/84 (20130101) G06F 21/305 (20130101) G06F 21/6245 (20130101) Signalling or Calling Systems; Order Telegraphs; Alarm Systems G08B 21/18 (20130101) G08B 21/0453 (20130101) G08B 25/00 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 20/17 (20180101) G16H 40/00 (20180101) G16H 40/40 (20180101) G16H 40/60 (20180101) G16H 40/67 (20180101) G16H 50/30 (20180101) G16H 80/00 (20180101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/30 (20130101) H04L 9/088 (20130101) H04L 63/101 (20130101) H04L 67/34 (20130101) Wireless Communication Networks H04W 76/10 (20180201) H04W 76/14 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123554 | Heller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida); Old Dominion University (Norfolk, Virginia) |
| INVENTOR(S) | Richard Heller (Tampa, Florida); Loree C. Heller (Tampa, Florida); Mark Jeffery Jaroszeski (Wesley Chapel, Florida) |
| ABSTRACT | A method and system for delivering a molecule to a specific area of a tissue by controlling temperature and impedance is presented. The method is generally comprised of applying heat to a biological structure, such as cells or tissues, to heat the biological structure to a preset temperature after which at least one electroporation pulse is administered to the biological structure. Impedance is measured as a feedback control mechanism after each pulse and pulse parameters are adjusted accordingly until desired impedance is reached. The system generally comprises an electroporation system capable of generating at least one pulse, measuring impedance and measuring temperature. The method may be used to deliver a molecule such as a vaccine or therapeutic to a biological structure, such as for prevention or treatment of SARS-CoV-2 infection. |
| FILED | Wednesday, November 25, 2020 |
| APPL NO | 17/104833 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 7/007 (20130101) A61F 2007/0071 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/327 (20130101) Original (OR) Class A61N 5/0625 (20130101) A61N 2005/0652 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123723 | Dong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Vy M. Dong (Irvine, California); Faben A. Cruz (Irvine, California); Xuesong Wu (Irvine, California); Steven M. Bischof (Humble, Texas); Stephen Karl Murphy (Cambridge, Massachusetts) |
| ABSTRACT | Catalyst compositions for the conversion of aldehyde compounds and primary alcohol compounds to olefins are disclosed herein. Reactions include oxidative dehydroxymethylation processes and oxidative dehydroformylation methods, which are beneficially conducted in the presence of a sacrificial acceptor of H2 gas, such as N,N-dimethylacrylamide. |
| FILED | Monday, February 25, 2019 |
| APPL NO | 16/284076 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0205 (20130101) B01J 31/0247 (20130101) B01J 31/2295 (20130101) B01J 31/2457 (20130101) Original (OR) Class B01J 2231/763 (20130101) B01J 2531/822 (20130101) Acyclic or Carbocyclic Compounds C07C 1/24 (20130101) C07C 1/2076 (20130101) C07C 11/02 (20130101) C07C 2531/04 (20130101) C07C 2531/22 (20130101) C07C 2531/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123732 | Kelly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Ryan T. Kelly (West Richland, Washington); Ying Zhu (Richland, Washington); Richard D. Smith (Richland, Washington) |
| ABSTRACT | Provided herein are methods and systems for biochemical analysis, including compositions and methods for processing and analysis of small cell populations and biological samples (e.g., a robotically controlled chip-based nanodroplet platform). In particular aspects, the methods described herein can reduce total processing volumes from conventional volumes to nanoliter volumes within a single reactor vessel (e.g., within a single droplet reactor) while minimizing losses, such as due to sample evaporation. |
| FILED | Wednesday, February 14, 2018 |
| APPL NO | 15/897022 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/00317 (20130101) B01J 2219/00367 (20130101) B01J 2219/00619 (20130101) B01J 2219/00621 (20130101) B01J 2219/00659 (20130101) B01J 2219/00702 (20130101) B01J 2219/00725 (20130101) B01J 2219/00743 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/00 (20130101) B01L 3/5088 (20130101) B01L 3/50853 (20130101) B01L 3/502753 (20130101) Original (OR) Class B01L 2200/142 (20130101) B01L 2300/0819 (20130101) B01L 2300/0822 (20130101) B01L 2300/0887 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/58 (20130101) C12M 41/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 60/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 1/34 (20130101) G01N 1/2813 (20130101) G01N 30/88 (20130101) G01N 33/68 (20130101) G01N 33/4833 (20130101) G01N 2001/284 (20130101) G01N 2030/8831 (20130101) Optical Elements, Systems, or Apparatus G02B 21/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124449 | Shih |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Wei-Chuan Shih (Houston, Texas) |
| ABSTRACT | The present disclosure relates to the fabrication and characterization of an optical fiber capable of firing light virtually from any point along its circumferential surface. The optical fiber is preferably prepared by laser micromachining. In preferred embodiments, laser radiation is focused onto a multimode optical fiber axis, forming a conical-shaped cavity (side window) in the fiber core. Because of the total internal reflection when the laser beam reaches the side window-outside medium interface, the beam is reflected to the side of the optical fiber. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 16/326986 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 25/68 (20130101) C03C 25/1063 (20180101) C03C 25/6208 (20180101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124476 | Schoenfisch et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina); Novan, Inc. (Morrisville, North Carolina) |
| ASSIGNEE(S) | Novan, Inc. (Durham, North Carolina); The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Mark Schoenfisch (Chapel Hill, North Carolina); Yuan Lu (Chapel Hill, North Carolina); Nathan Stasko (Chapel Hill, North Carolina); Jian Bao (Cary, North Carolina) |
| ABSTRACT | Provided here are nitric oxide-releasing compounds that include at least two different NO donor functional groups of the same class. In some embodiments, such nitric oxide-releasing compounds are macromolecules such as dendrimer and co-condensed silica. Pharmaceutical compositions, wound dressings, kits and methods of treatments are also provided herein. |
| FILED | Thursday, August 29, 2019 |
| APPL NO | 16/555673 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/655 (20130101) Acyclic or Carbocyclic Compounds C07C 247/10 (20130101) C07C 281/20 (20130101) Original (OR) Class C07C 291/02 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124483 | Novotny et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Christopher Novotny (San Francisco, California); Kevan Shokat (San Francisco, California); Natalia Jura (San Francisco, California) |
| ABSTRACT | Described herein, inter alia, are compositions of HER3 ligands and methods for treating diseases using the same. |
| FILED | Friday, September 02, 2016 |
| APPL NO | 15/756543 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) A61K 31/4706 (20130101) A61K 31/4709 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 215/54 (20130101) Original (OR) Class C07D 239/94 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124489 | Zhou et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jia Zhou (Galveston, Texas); Zhiqing Liu (Galveston, Texas); Na Ye (Galveston, Texas); Fang Mei (Galveston, Texas); Xiaodong Cheng (Galveston, Texas) |
| ASSIGNEE(S) | Board of Regents, the University of Texas System (Austin, Texas) |
| INVENTOR(S) | Jia Zhou (Galveston, Texas); Zhiqing Liu (Galveston, Texas); Na Ye (Galveston, Texas); Fang Mei (Galveston, Texas); Xiaodong Cheng (Galveston, Texas) |
| ABSTRACT | Embodiments are directed to a series of novel EPAC antagonists that are designed, synthesized and evaluated in an effort to develop diversified analogues based on the scaffold of the previously identified high-throughput (HTS) hit ESI-09. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 16/499050 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Heterocyclic Compounds C07D 261/08 (20130101) Original (OR) Class C07D 261/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124490 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Memphis, Tennessee); UNIVERSITY OF MEMPHIS (Memphis, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Memphis, Tennessee); UNIVERSITY OF MEMPHIS (Memphis, Tennessee) |
| INVENTOR(S) | Duane D. Miller (Memphis, Tennessee); Gabor G. Tigyi (Memphis, Tennessee); Souvik Banerjee (Memphis, Tennessee); Abby L. Parrill-Baker (Memphis, Tennessee) |
| ABSTRACT | The present disclosure provides novel ATX inhibitors, and pharmaceutical compositions comprising said inhibitors, as well as methods of treatment comprising administration of said inhibitors. |
| FILED | Friday, June 02, 2017 |
| APPL NO | 16/305345 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 241/04 (20130101) C07D 265/30 (20130101) Original (OR) Class C07D 295/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124498 | Fischbach et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Michael A. Fischbach (San Francisco, California); Chun-Jun Guo (San Francisco, California); Christopher A. Voigt (Belmont, Massachusetts); Fang-Yuan Chang (Somerville, Massachusetts); Jon Clardy (Boston, Massachusetts); Thomas Wyche (Chelsea, Massachusetts) |
| ABSTRACT | Disclosed herein, inter alia, are compositions for modulating protease activity and treating cancer. |
| FILED | Wednesday, November 15, 2017 |
| APPL NO | 16/462460 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 237/20 (20130101) C07C 323/60 (20130101) Heterocyclic Compounds C07D 241/12 (20130101) C07D 241/18 (20130101) C07D 403/06 (20130101) C07D 403/12 (20130101) C07D 403/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124503 | Stoltz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Brian M. Stoltz (San Marino, California); Masaki Hayashi (Kanagawa, Japan); Satoshi Hashimoto (Tokyo, Japan) |
| ABSTRACT | This disclosure provides methods for intermolecular enantioselective C-acylation of lactams with quaternary stereogenic centers by applying a chiral Ni catalyst. The methods comprise treating a lactam of formula (IIa): with a chiral Ni catalyst, an aryl nitrile, and an aryl halide to provide compounds of formula (Ia): |
| FILED | Monday, August 06, 2018 |
| APPL NO | 16/055559 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 207/27 (20130101) C07D 207/273 (20130101) C07D 207/277 (20130101) C07D 409/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124504 | Roberts et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Scripps Research Institute (La Jolla, California); BlackThorn Therapeutics, Inc. (San Francisco, California) |
| ASSIGNEE(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California); BLACKTHORN THERAPEUTICS, INC. (San Francisco, California) |
| INVENTOR(S) | Edward Roberts (Fallbrook, California); Miguel A. Guerrero (San Diego, California); Mariangela Urbano (Del Mar, California); Hugh Rosen (La Jolla, California); Robert M. Jones (South San Francisco, California); Candace Mae Laxamana (South San Francisco, California); Xianrui Zhao (South San Francisco, California); Eric Douglas Turtle (Belmont, California) |
| ABSTRACT | Compounds are provided that antagonize the kappa-opioid receptor (KOR) and products containing such compounds, as well as to methods of their use and synthesis. Such compounds have the structure of Formula (I), or a pharmaceutically acceptable isomer, racemate, hydrate, solvate, isotope or salt thereof: wherein X, Y, R1, R2, R4, R5 R6, R7, R8 and R11 are as defined herein. |
| FILED | Friday, April 10, 2020 |
| APPL NO | 16/846136 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) A61P 25/06 (20180101) Heterocyclic Compounds C07D 413/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124520 | Gangjee |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Duquesne University of the Holy Spirit (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Aleem Gangjee (Allison Park, Pennsylvania) |
| ABSTRACT | The present invention provides a compound of Formula III, and salts thereof, and a pharmaceutical composition comprising a compound of Formula III: wherein R1 is selected from the group consisting of: wherein R2 is H or an alkyl group having from one to ten carbon atoms; R3 is H or an alkyl group having from one to ten carbon atoms; and R4 is H or an alkyl group having from one to ten carbon atoms. Methods of treating a patient with cancer with these compounds are also provided. |
| FILED | Wednesday, December 04, 2019 |
| APPL NO | 16/703180 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 239/42 (20130101) C07D 239/70 (20130101) C07D 239/94 (20130101) C07D 405/12 (20130101) C07D 487/00 (20130101) C07D 487/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124541 | Haskell-Luevano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Carrie Haskell-Luevano (Minneapolis, Minnesota); Mark David Ericson (Minneapolis, Minnesota) |
| ABSTRACT | The invention provides compounds having the general formula I: and salts thereof, wherein the variables Pro, DPro, DPhe, Arg, Trp, X1, X2, X3 and X4 have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions. |
| FILED | Tuesday, October 17, 2017 |
| APPL NO | 15/786005 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/12 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) Peptides C07K 7/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124544 | Srivastava et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Arun Srivastava (Gainesville, Florida); George Vladimirovich Aslanidi (Austin, Minnesota); Kim M. Van Vliet (Gainesville, Florida); Mavis Agbandje-McKenna (Gainesville, Florida) |
| ABSTRACT | The present invention provides AAV capsid proteins comprising modification of one or a combination of the surface-exposed lysine, serine, threonine and/or tyrosine residues in the VP3 region. Also provided are rAAV virions comprising the AAV capsid proteins of the present invention, as well as nucleic acid molecules and rAAV vectors encoding the AAV capsid proteins of the present invention. Advantageously, the rAAV vectors and virions of the present invention have improved efficiency in transduction of a variety of cells, tissues and organs of interest, when compared to wild-type rAAV vectors and virions. |
| FILED | Tuesday, August 08, 2017 |
| APPL NO | 15/672265 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/42 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class C07K 14/805 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) C12N 2750/14171 (20130101) C12N 2810/6027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124546 | Samulski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| INVENTOR(S) | Richard Jude Samulski (Chapel Hill, North Carolina); Jayme Warischalk (Chapel Hill, North Carolina) |
| ABSTRACT | This invention relates to modified parvovirus capsid proteins with enhanced transduction efficiency, viral vectors comprising the same, and methods of using the same for delivery of nucleic acids to a cell or a subject. |
| FILED | Wednesday, December 14, 2016 |
| APPL NO | 16/061952 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/76 (20130101) Peptides C07K 14/015 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124550 | Petrou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Queensland (St Lucia, Australia); The Florey Institute of Neuroscience and Mental Health (Parkville, Australia); The Johns Hopkins University (Baltimore, Maryland); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE UNIVERSITY OF QUEENSLAND (Queensland, Australia); THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); THE FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH (Victoria, Australia); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Steven Petrou (Eltham, Australia); Glenn King (Chapel Hill, Australia); Frank Bosmans (Annapolis, Maryland); David Julius (Walnut Creek, California); Jeremiah Osteen (San Francisco, California); Chuchu Zhang (Brookline, Massachusetts) |
| ABSTRACT | This invention relates to peptides and their use for modulating sodium channels. More particularly, the present invention relates to peptides and their use in methods of enhancing Nav1.1 activity and for treating or preventing conditions associated with Nav1.1 activity. |
| FILED | Friday, December 09, 2016 |
| APPL NO | 16/061074 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/1767 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/08 (20180101) Peptides C07K 14/43518 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124551 | Cohen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Pinchas Cohen (Los Angeles, California); Kelvin Yen (Los Angeles, California) |
| ABSTRACT | Described herein is a novel, mitochondrial encoded, open reading frame, that leads to the production of a new mitochondrial peptide. Residing within the ND-Two subunit, a specific small nucleotide polymorphism disrupts expression of this mitochondrial peptide, and is correlated with an increase in obesity and diabetes, particularly in certain ethnic populations. In vitro administration of the peptide increases insulin secretion, decreases fat accumulation and improves glucose uptake in muscle cell. Antibodies generated against the peptide can be used for detecting peptide deficiency, in addition to SNP detection, supporting diagnostic approaches. In vivo studies further revealed that administration of the peptide improves glucose tolerance, thereby providing a new therapeutic avenue for a novel diabetes therapy and decreases bodyweight, thus serving as a novel obesity therapy. Generation of synthetic analogs further enhance or abrogated activity relative to the natural peptide. |
| FILED | Friday, June 23, 2017 |
| APPL NO | 16/311599 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/10 (20180101) Peptides C07K 7/08 (20130101) C07K 14/47 (20130101) Original (OR) Class C07K 14/435 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/04 (20130101) G01N 2800/042 (20130101) G01N 2800/044 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124553 | Wang |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Xinglong Wang (Cleveland, Ohio) |
| ABSTRACT | A method of treating a neurodegenerative disease in a subject includes administering to the subject a therapeutically effective amount of a TDP-43 mitochondrial localization inhibitor. |
| FILED | Friday, April 07, 2017 |
| APPL NO | 16/090786 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 7/06 (20130101) C07K 14/4713 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124558 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| ASSIGNEE(S) | The Feinstein Institutes for Medical Research (Manhasset, New York) |
| INVENTOR(S) | Haichao Wang (Edison, New Jersey); Wei Li (Plainview, New York); Jianhua Li (New York, New York); Kevin J. Tracey (Old Greenwich, Connecticut) |
| ABSTRACT | A method of treating a disease or reducing the development of a symptom of a disease in a subject by administering to the subject an amount of tetranectin protein or a tetranectin peptide agonist effective to treat or reduce development of the disease or disease symptom. |
| FILED | Monday, June 04, 2018 |
| APPL NO | 16/617811 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/00 (20180101) A61P 29/00 (20180101) Peptides C07K 7/08 (20130101) C07K 14/7056 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124562 | Holtzman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri); Denali Therapeutics Inc. (South San Francisco, California) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | David Holtzman (St. Louis, Missouri); Hong Jiang (St. Louis, Missouri); Fan Liao (St. Louis, Missouri); Thu Nga Bien-Ly (South San Francisco, California); Mark S. Dennis (South San Francisco, California); Jing Guo (South San Francisco, California); Adam P. Silverman (South San Francisco, California); Ryan J. Watts (South San Francisco, California); Yin Zhang (South San Francisco, California) |
| ABSTRACT | The present disclosure encompasses compositions and methods for effectively treating at least one symptom or sign of A plaque or cerebral amyloid angiopathy (CAA) associated symptoms, or for decreasing amyloid plaque load or CAA load. The method comprises administering an effective amount of an anti-ApoE antibody to a mammalian subject, such as to a human. |
| FILED | Friday, October 27, 2017 |
| APPL NO | 16/345637 |
| ART UNIT | 1699 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0085 (20130101) A61K 9/127 (20130101) A61K 31/192 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/33 (20130101) C07K 2317/90 (20130101) C07K 2317/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124569 | Freeman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Emory University (Atlanta, Georgia); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); President And Fellows Of Harvard College (Cambridge, Massachusetts); Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Gordon J. Freeman (Brookline, Massachusetts); Rafi Ahmed (Atlanta, Georgia); Arlene H. Sharpe (Brookline, Massachusetts); Masao Hashimoto (Decatur, Georgia); Hyun T. Jin (Atlanta, Georgia) |
| ABSTRACT | The present invention relates to methods of reducing liver PD-1-expressing CD8+ T cells using PD-1 Fc fusion proteins that bind Fc receptors, as well as diagnostic, prognostic, therapeutic methods and compositions related thereto. |
| FILED | Friday, September 16, 2016 |
| APPL NO | 15/758515 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 41/0038 (20130101) A61K 2039/505 (20130101) A61K 2039/545 (20130101) A61K 2039/572 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 35/00 (20180101) Peptides C07K 14/70503 (20130101) C07K 16/2818 (20130101) Original (OR) Class C07K 2317/73 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124571 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Alex Yee-Chen Huang (Cleveland, Ohio); Agne Petrosiute (Cleveland, Ohio) |
| ABSTRACT | A method of sensitizing cancer to immunotherapy in a subject in need thereof includes administering to the subject a therapeutically effective amount of a CdK5 inhibitor to suppress immune checkpoint PD-L1. |
| FILED | Wednesday, May 24, 2017 |
| APPL NO | 16/303846 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/39541 (20130101) A61K 39/39541 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/70596 (20130101) C07K 16/2827 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Enzymes C12Y 207/11022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124580 | Morgan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard A. Morgan (Center Harbor, New Hampshire); Steven A. Rosenberg (Potomac, Maryland) |
| ABSTRACT | The invention provides chimeric antigen receptors (CARs) comprising an antigen binding domain of human antibody 139, an extracellular hinge domain, a transmembrane domain, and an intracellular domain T cell receptor signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a host and methods of treating or preventing cancer in a host are also disclosed. |
| FILED | Friday, January 24, 2020 |
| APPL NO | 16/751643 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0011 (20130101) A61K 48/00 (20130101) A61K 2039/505 (20130101) A61K 2039/5156 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70503 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70575 (20130101) C07K 14/70578 (20130101) C07K 14/70596 (20130101) C07K 16/32 (20130101) Original (OR) Class C07K 16/2863 (20130101) C07K 16/3053 (20130101) C07K 2317/21 (20130101) C07K 2319/00 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/30 (20130101) C07K 2319/33 (20130101) C07K 2319/70 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57492 (20130101) G01N 2333/71 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124605 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Jianjun Cheng (Champaign, Illinois); Menghua Xiong (Urbana, Illinois); Ziyuan Song (Urbana, Illinois) |
| ABSTRACT | The invention provides antimicrobial polypeptides (AMPs) with high radial amphiphilicity. Unlike typical AMPs characterized by facial amphiphilicity or biomimetic antimicrobial polymers with randomly distributed charged and hydrophobic groups, these new AMPs are homo-polypeptides with radially amphiphilic structure. They adopt a stable α-helical conformation with a hydrophobic helical core and a charged exterior shell, formed by flexible hydrophobic side chains with terminal charge group. The radially amphiphilic polypeptides offer several advantages over conventional AMPs with regard to stability against protease and simplicity of design. They also exhibit high antibacterial activity against both Gram-negative and Gram-positive bacteria and low hemolytic activity. The AMPs thus provide a general platform for treating drug-resistant bacterial infections. |
| FILED | Monday, June 27, 2016 |
| APPL NO | 15/739090 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) A01N 43/40 (20130101) A01N 43/42 (20130101) A01N 43/50 (20130101) A01N 43/52 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/43 (20130101) A61K 31/65 (20130101) A61K 31/65 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/785 (20130101) A61K 31/7036 (20130101) A61K 31/7036 (20130101) A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101) C08G 69/48 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124765 | Thomson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | James A. Thomson (Madison, Wisconsin); Nicholas E. Propson (Houston, Texas); Michael P. Schwartz (Madison, Wisconsin); Zhonggang Hou (Madison, Wisconsin); Gene I. Uenishi (Madison, Wisconsin); Igor I. Slukvin (Verona, Wisconsin); William L. Murphy (Waunakee, Wisconsin); Jue Zhang (Madison, Wisconsin) |
| ABSTRACT | The present invention relates to methods for deriving human hematopoietic progenitors, primitive macrophages, and microglial cells from human pluripotent stem cells. In particular, provided herein are highly efficient and reproducible methods of obtaining human primitive macrophages and microglia from human pluripotent stem cells, where the primitive macrophages and microglia can be suitable for clinically relevant therapeutic applications. |
| FILED | Friday, September 21, 2018 |
| APPL NO | 16/138724 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0068 (20130101) C12N 5/0606 (20130101) C12N 5/0622 (20130101) Original (OR) Class C12N 5/0645 (20130101) C12N 5/0647 (20130101) C12N 5/0697 (20130101) C12N 2500/25 (20130101) C12N 2501/15 (20130101) C12N 2501/22 (20130101) C12N 2501/115 (20130101) C12N 2501/999 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) C12N 2513/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5014 (20130101) G01N 33/5058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124766 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (, None) |
| INVENTOR(S) | Frances Eun-Hyung Lee (Atlanta, Georgia); Ignacio Sanz (Atlanta, Georgia); Doan Nguyen (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to growth media and environments for in vitro culturing of cells that produce or are capable of producing antibodies. In certain embodiments, the media comprises IL-6, fibronectin, and typically a saccharide. In certain embodiments, the disclosure contemplates cell culture compositions comprising IL-6 and fibronectin that are derived from proteins secreted from mesenchymal stromal/stem cells (MSCs). In certain embodiments, the disclosure contemplates enclosures comprising culture compositions disclosed herein that are in ambient air or optionally in an environment wherein oxygen is absent or at a low concentration. |
| FILED | Thursday, June 09, 2016 |
| APPL NO | 15/735933 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0635 (20130101) Original (OR) Class C12N 2500/02 (20130101) C12N 2500/32 (20130101) C12N 2500/34 (20130101) C12N 2500/38 (20130101) C12N 2500/60 (20130101) C12N 2501/24 (20130101) C12N 2501/25 (20130101) C12N 2501/998 (20130101) C12N 2501/2305 (20130101) C12N 2501/2306 (20130101) C12N 2501/2321 (20130101) C12N 2502/1358 (20130101) C12N 2533/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124769 | Murphy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOSTON MEDICAL CENTER CORPORATION (Boston, Massachusetts); TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | BOSTON MEDICAL CENTER CORPORATION (Boston, Massachusetts); TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | George J. Murphy (Boston, Massachusetts); David H. Sherr (West Roxbury, Massachusetts); Sarah S. Rozelle (Jamaica Plain, Massachusetts); Brenden W. Smith (Warwick, Rhode Island) |
| ABSTRACT | This disclosure provides methods of making a megakaryocyte-erythroid progenitor cell (MEP), comprising differentiating a MEP precursor cell into a MEP in culture in the presence of an aryl hydrocarbon receptor (AhR) modulator. In some embodiments the AhR modulator is an AhR antagonist. In some embodiments the AhR modulator is an AhR agonist. In some embodiments the methods comprise culturing MEP precursor cells in the presence of an AHR antagonist and then culturing MEP precursor cells in the presence of an AHR agonist. In some embodiments the stem cell is a pluripotent stem cell. In some embodiments the MEP co-expresses CD41 and CD235. In some embodiments the number of MEPs produced in the culture increases exponentially. Methods of making a red blood cell (RBC) by culturing a MEP in the presence of an AhR modulator are also provided. Methods of making a megakaryocyte and/or a platelet, comprising culturing a MEP in the presence of an AhR modulator are also provided. In some embodiments the AhR modulator is an AhR antagonist. This disclosure also provides compositions comprising at least 1 million MEPs per ml and compositions in which at least 50% of the cells are MEPs, among other things. |
| FILED | Saturday, February 17, 2018 |
| APPL NO | 15/898526 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/404 (20130101) A61K 31/655 (20130101) A61K 35/18 (20130101) A61K 35/19 (20130101) A61K 45/06 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0641 (20130101) C12N 5/0644 (20130101) C12N 5/0647 (20130101) Original (OR) Class C12N 2501/60 (20130101) C12N 2501/998 (20130101) C12N 2501/999 (20130101) C12N 2506/03 (20130101) C12N 2506/45 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/80 (20130101) G01N 33/86 (20130101) G01N 33/5044 (20130101) G01N 2500/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124779 | Desir |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Gary Desir (Woodbridge, Connecticut) |
| ABSTRACT | The present invention includes compositions and methods for detecting, treating and preventing renal and pancreatic diseases and disorders. |
| FILED | Thursday, June 27, 2019 |
| APPL NO | 16/454223 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0036 (20130101) Original (OR) Class C12N 15/1137 (20130101) C12N 2310/14 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/26 (20130101) Enzymes C12Y 106/03 (20130101) C12Y 306/03008 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2333/90209 (20130101) G01N 2800/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124782 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); Alexis Christine Komor (San Diego, California) |
| ABSTRACT | Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins of Cas9 and nucleic acid editing enzymes or enzyme domains, e.g., deaminase domains, are provided. In some embodiments, methods for targeted nucleic acid editing are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of Cas9 and nucleic acid editing enzymes or domains, are provided. |
| FILED | Wednesday, April 03, 2019 |
| APPL NO | 16/374634 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/50 (20130101) A61K 38/465 (20130101) A61K 47/61 (20170801) Peptides C07K 2319/00 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/78 (20130101) C12N 9/6472 (20130101) C12N 15/01 (20130101) C12N 15/102 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 301/00 (20130101) C12Y 301/22 (20130101) C12Y 304/22062 (20130101) C12Y 305/04 (20130101) C12Y 305/04001 (20130101) C12Y 305/04004 (20130101) C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124783 | Rajan |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Rakhi Rajan (Norman, Oklahoma) |
| ABSTRACT | Bridge helix-modified variant Cas9 proteins having improved DNA cleavage selectivity in comparison to wild type versions of the Cas9 proteins, nucleic acids encoding the variant proteins, host cells containing the nucleic acids, and methods of their use. |
| FILED | Friday, September 13, 2019 |
| APPL NO | 16/570555 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/70 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124785 | Helmerhorst et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Eva J. Helmerhorst (Boston, Massachusetts); Guoxian Wei (Malden, Massachusetts); Na Tian (Wellesley, Massachusetts); Detlef Schuppan (Mainz, Germany) |
| ABSTRACT | There are gluten-degrading enzymes found in Rothia species bacteria that are subtilisins that belonging to the S8A family of serine protease family. The Rothia sp. derived subtilisin-like enzymes have the conserved catalytic triad composed of a Ser, His, and Asp residues that is characteristic of the serine protease family. The Rothia subtilisin enzymes are potent at cleaving proline-containing proteins, cleaving the second peptide bond after proline in the XPX1 motif, where X is any amino acid, P is proline and X1 is a hydrophobic amino acid, e.g. the XPQ motif, where Q is glutamine. Embodiments herein provide isolated enzyme compositions and formulations comprising subtilisins gluten-degrading enzyme from a Rothia species bacteria. Also provided herein are methods of treatment of celiac disease or a related disorder, treatment of gluten-containing foodstuff, degrading and/or detoxifying gluten comprising the subtilisins gluten-degrading enzyme and/or compositions. |
| FILED | Friday, February 10, 2017 |
| APPL NO | 16/076852 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/135 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/482 (20130101) A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/52 (20130101) Original (OR) Class Enzymes C12Y 304/21026 (20130101) C12Y 304/21062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124787 | Wagner et al. |
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| FUNDED BY |
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| APPLICANT(S) | TAKEDA PHARMACEUTICAL COMPANY LIMITED (Osaka, Japan); CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | Takeda Pharmaceutical Company Limited (Osaka, Japan); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Denisa D. Wagner (Dover, Massachusetts); Anil Kumar Chauhan (Brookline, Massachusetts); Friedrich Scheiflinger (Vienna, Austria); Barbara Plaimauer (Vienna, Austria) |
| ABSTRACT | This invention relates to a pharmaceutical composition having thrombolytic activity comprising ADAMTS13, and to methods for treating or preventing a disorder associated with the formation and/or the presence of one or more thrombus and to methods of disintegrating one or more thrombus in a patient in need thereof. Furthermore, the invention relates to the use of a pharmaceutically effective amount of ADAMTS13 for the preparation of a pharmaceutical composition for treating or preventing a disorder associated with the formation or the presence of one or more thrombus and for disintegrating one or more thrombus in a patient in need thereof. |
| FILED | Wednesday, January 30, 2019 |
| APPL NO | 16/262180 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/17 (20130101) A61K 38/4886 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6489 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124791 | Labaer et al. |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Joshua Labaer (Chandler, Arizona); Kevin Gorman (Chicago, Illinois); Brian Kay (Chicago, Illinois); Jie Wang (Tempe, Arizona); Ji Qiu (Chandler, Arizona) |
| ABSTRACT | Methods for screening of affinity reagents for many target proteins of interest simultaneously. Arrayed targets (e.g., peptide, protein, RNA, cell, etc.) are used in affinity selection experiments to reduce the amount of target needed and to improve the throughput of discovering recombinant affinity reagents to a large collection of targets. |
| FILED | Tuesday, September 13, 2016 |
| APPL NO | 15/748946 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1037 (20130101) Original (OR) Class C12N 15/1041 (20130101) C12N 15/1062 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 1/6811 (20130101) C12Q 2565/501 (20130101) C12Q 2565/515 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 30/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124793 | Brar |
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| FUNDED BY |
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| APPLICANT(S) | Jaan Biotherapeutics LLC (San Diego, California) |
| ASSIGNEE(S) | Jaan Biotherapeutics LLC (San Diego, California) |
| INVENTOR(S) | Bhawanjit Kaur Brar (La Jolla, California) |
| ABSTRACT | Disclosed herein include microRNA antagonists, therapeutic compositions that include one or more of such microRNA antagonists, and methods of treating and/or ameliorating cardiac diseases and/or muscular dystrophy disorders with the microRNA antagonists. Also included are combination therapies, wherein a therapeutic composition disclosed herein and an additional therapy agent are provided to a subject having or suspected of having cardiac disease and/or muscular dystrophy disorder. In particular, some embodiments disclosed herein relate to compositions and methods for transiently administering a mixture of microRNA antagonists for promoting cardiomyocyte proliferation and cardiac regeneration. |
| FILED | Tuesday, August 11, 2020 |
| APPL NO | 16/990470 |
| ART UNIT | 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/113 (20130101) C12N 2310/141 (20130101) C12N 2310/315 (20130101) C12N 2310/344 (20130101) C12N 2310/346 (20130101) C12N 2310/3231 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124794 | Milsom et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | THE CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Michael Milsom (Dossenheim, Germany); David A. Williams (Dover, Massachusetts); Richard Gregory (Brookline, Massachusetts) |
| ABSTRACT | Embodiments herein provide specially designed synthetic BCL11A-targeting microRNAs for RNA polymerase II expression, and methods of use to treat hemoglobinopathies such as sickle cell disease or thalassemia by increasing the expression levels of fetal hemoglobin levels. |
| FILED | Monday, April 06, 2020 |
| APPL NO | 16/841259 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/113 (20130101) C12N 15/1135 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2310/141 (20130101) C12N 2310/531 (20130101) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) C12N 2740/10032 (20130101) C12N 2740/10043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124796 | Sharp et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Phillip A. Sharp (Newton, Massachusetts); Feng Zhang (Cambridge, Massachusetts); Randall Jeffrey Platt (Basel, Switzerland); Sidi Chen (Milford, Connecticut) |
| ABSTRACT | The invention involves inducing 3-50 or more mutations (e.g., any whole number between 3 and 50 of mutations, with it noted that in some embodiments there can be up to 16 different RNA(s), e.g., sgRNAs each having its own a promoter, in a vector, such as AAV, and that when each sgRNA does not have its own promoter, there can be twice to thrice that amount of different RNA(s), e.g., sgRNAs, e.g., 32 or even 48 different guides delivered by one vector) in transgenic Cas9 eukaryotes to model genetic disease, e.g. cancer. The invention comprehends testing putative treatments with such models, e.g., testing putative chemical compounds that may be pharmaceutically relevant for treatment or gene therapy that may be relevant for treatment, or combinations thereof. The invention allows for the study of genetic diseases and putative treatments to better understand and alleviate a genetic disease or a condition, e.g., cancer. |
| FILED | Thursday, March 23, 2017 |
| APPL NO | 15/467888 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0275 (20130101) A01K 2217/00 (20130101) A01K 2227/105 (20130101) A01K 2267/0306 (20130101) A01K 2267/0331 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) Original (OR) Class C12N 15/85 (20130101) C12N 15/102 (20130101) C12N 15/111 (20130101) C12N 15/907 (20130101) C12N 15/8509 (20130101) C12N 2310/20 (20170501) C12N 2310/531 (20130101) C12N 2310/3519 (20130101) C12N 2320/10 (20130101) C12N 2320/32 (20130101) C12N 2750/14143 (20130101) C12N 2830/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124799 | Howard et al. |
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| FUNDED BY |
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| APPLICANT(S) | Applied Biotechnology Institute, Inc. (San Luis Obsipo, California) |
| ASSIGNEE(S) | Applied Biotechnology Institute, Inc. (San Luis Obsipo, California) |
| INVENTOR(S) | John Howard (San Luis Obispo, California); Celine Hayden (San Louis Obispo, California) |
| ABSTRACT | Vaccines, methods of producing, and methods of using are provided in which a protective response to Valley Fever disease is produced when administered to an animal. The vaccine provides for expression of Coccidioides sp. Ag2 polypeptide in a plant or plant part, linked to a promoter preferentially directing expression to seed tissue of the plant or plant part. Further embodiments provide the polypeptide is targeted to the cell wall, vacuole or endoplasmic reticulum. The polypeptide may be fused to a dendritic cell targeting dendritic cell or a heat labile enterotoxin. Increased expression levels in the plant or plant part are obtained. The vaccine comprising the plant-produced Ag2 polypeptide may be a glucan chitin particle comprising the Ag2 polypeptide. The plant or plant materials in an embodiment may be orally administered. |
| FILED | Wednesday, June 12, 2019 |
| APPL NO | 16/439301 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0002 (20130101) A61K 2039/57 (20130101) Peptides C07K 14/37 (20130101) C07K 2319/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/62 (20130101) C12N 15/8234 (20130101) C12N 15/8257 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124815 | Ernst et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Maryland, Baltimore (Baltimore, Maryland); University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Robert K. Ernst (Silver Spring, Maryland); Mark Pelletier (Brunswick, Maryland); Adeline Hajjar (Seattle, Washington) |
| ABSTRACT | Embodiments of the disclosure provide for unique lipooligosaccharide/lipid A-based mimetics for use as adjuvants. Methods of generating lipooligosaccharide/lipid A-based mimetics are provided that utilize recombinantly engineered bacteria to produce the mimetics, including, for example, addition of one or more particular enzymes such as acyltransferases, deacylases, phosphatases, or glycosyltransferases. |
| FILED | Tuesday, June 04, 2019 |
| APPL NO | 16/431536 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/739 (20130101) A61K 39/39 (20130101) A61K 39/099 (20130101) A61K 39/0291 (20130101) A61K 2039/55572 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 11/04 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/12 (20130101) Original (OR) Class C12P 19/26 (20130101) C12P 19/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124830 | Lan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regent of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Freeman Lan (San Francisco, California); Benjamin Demaree (Berkeley, California); Iain Clark (San Francisco, California); Adam R. Abate (Daly City, California) |
| ABSTRACT | The present disclosure provides ultrahigh-throughput single cell genomic sequencing methods, referred to herein as “SiC-seq”, which methods include encapsulating single cells in molten gel droplets to facilitate bulk cell lysis and purification of genomic DNA in microgels. Systems and devices for practicing the subject methods are also provided. |
| FILED | Wednesday, April 15, 2020 |
| APPL NO | 16/849344 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 2565/629 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124838 | Ghobrial et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Irene Ghobrial (Wellesley, Massachusetts); Salomon Manier (Lille, France); Yuji Mishima (Tokyo, Japan) |
| ABSTRACT | Provided herein are non-invasive methods and biomarkers that identify progression and clonal evolution of plasma cell dyscrasias. Also provided are materials and methods for the diagnosis, prognosis, staging, and monitoring of plasma cell dyscrasias based on the presence of the bio markers in a blood biopsy, as well as methods for monitoring the progression of a plasma cell dyscrasia, determining the efficacy of a therapeutic agent, determining a targeted therapy related to a plasma cell dyscrasia, and/or treating a plasma cell dyscrasia. The methods provided herein provide several advantages over invasive biopsies. |
| FILED | Friday, August 05, 2016 |
| APPL NO | 15/742815 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5011 (20130101) G01N 33/5038 (20130101) G01N 33/5044 (20130101) G01N 2570/00 (20130101) G01N 2800/22 (20130101) G01N 2800/52 (20130101) G01N 2800/56 (20130101) G01N 2800/60 (20130101) G01N 2800/7028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124841 | Oliver et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF UTAH RESEARCH FOUNDATION (Salt Lake City, Utah) |
| ASSIGNEE(S) | University Of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Trudy Oliver (Salt Lake City, Utah); Martin Sos (Salt Lake City, Utah); Rob Wechsler-Reya (Salt Lake City, Utah) |
| ABSTRACT | Described herein are methods and compositions useful in detecting, diagnosing and treating small cell lung cancer. Transgenic animal models and cell lines are disclosed for the study of a small cell lung cancer subtype. Methods of screening and identifying active agents for the treatment of a small cell lung cancer subtype as well as methods of identifying patients susceptible to treatment with aurora kinase inhibitors are also provided. |
| FILED | Friday, October 27, 2017 |
| APPL NO | 16/335368 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124845 | Pomper et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (BALTIMORE, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins university (Baltimore, Maryland) |
| INVENTOR(S) | Martin G. Pomper (Baltimore, Maryland); Mark Castanares (Balitmore, Maryland); Il Minn (Ellicott City, Maryland); Shawn Lupold (Ellicott City, Maryland) |
| ABSTRACT | The presently disclosed subject matter provides methods, reporter gene constructs, and kits for using prostate-specific membrane antigen (PSMA) as an imaging reporter to image a variety of cells and tissues. |
| FILED | Wednesday, March 18, 2015 |
| APPL NO | 15/126749 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0021 (20130101) A61K 51/0406 (20130101) A61K 51/0455 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/485 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 2710/10043 (20130101) C12N 2710/10044 (20130101) C12N 2710/10071 (20130101) C12N 2710/16143 (20130101) C12N 2710/16222 (20130101) C12N 2830/60 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Original (OR) Class Enzymes C12Y 304/17021 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57434 (20130101) G01N 33/57492 (20130101) G01N 33/57496 (20130101) G01N 2333/705 (20130101) G01N 2458/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124846 | Green et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Alexander A. Green (Scottsdale, Arizona); Peng Yin (Brookline, Massachusetts); James J. Collins (Newton, Massachusetts); Jongmin Kim (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides novel and versatile classes of riboregulators, including inter alia activating and repressing riboregulators, switches, and trigger and sink RNA, and methods of their use for detecting RNAs in a sample such as a well and in modulating protein synthesis and expression. |
| FILED | Tuesday, July 14, 2015 |
| APPL NO | 15/326054 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1138 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125739 | Sharei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Armon R. Sharei (Watertown, Massachusetts); Marc Lajoie (Seattle, Washington); Klavs F. Jensen (Lexington, Massachusetts); Robert S. Langer (Newton, Massachusetts) |
| ABSTRACT | Gene editing can be performed by introducing gene-editing components into a cell by mechanical cell disruption. Related apparatus, systems, techniques, and articles are also described. The methods and systems of the invention solve the problem of intracellular delivery of gene editing components and gene editing complexes to target cells. The results described herein indicate that delivery of gene editing components, e.g., protein, ribonucleic acid (RNA), and deoxyribonucleic acid (DNA), by mechanical disruption of cell membranes leads to successful gene editing. Because intracellular delivery of gene editing materials is a current challenge, the methods provide a robust mechanism to engineer target cells without the use of potentially harmful viral vectors or electric fields. |
| FILED | Tuesday, January 12, 2016 |
| APPL NO | 15/542892 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5002 (20130101) Original (OR) Class G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125741 | Que et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Emily L. Que (Chicago, Illinois); Thomas V. O'Halloran (Chicago, Illinois); Teresa K. Woodruff (Chicago, Illinois) |
| ABSTRACT | The invention relates generally to compositions and methods for the detection of zinc. In particular, compositions and methods are provided to detect changes in cellular zinc concentration and to correlate them to cellular phenomena. |
| FILED | Tuesday, February 20, 2018 |
| APPL NO | 15/899543 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/40 (20130101) A61K 31/69 (20130101) A61K 31/435 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/022 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 31/22 (20130101) G01N 33/52 (20130101) Original (OR) Class G01N 33/84 (20130101) G01N 33/5091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125743 | Green et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Alexander Green (Scottsdale, Arizona); Duo Ma (Tempe, Arizona); Luhui Shen (Tempe, Arizona); Chris Diehnelt (Chandler, Arizona) |
| ABSTRACT | Provided herein are methods and systems for low-cost, low-equipment detection of pathogens in biological sample. In particular, provided herein is a low-cost method for detecting norovirus that provides reliable, visible test with femtomolar, attomolar, and zeptomolar detection limits and that uses materials suitable for deployment of the methods in the field. |
| FILED | Tuesday, February 19, 2019 |
| APPL NO | 16/279045 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 19/00 (20130101) C07K 2317/60 (20130101) C07K 2317/569 (20130101) C07K 2318/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/569 (20130101) G01N 33/5308 (20130101) G01N 33/5434 (20130101) G01N 33/54306 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125755 | Birnbaum et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Michael Edward Birnbaum (Stanford, California); Juan Luis Mendoza (Redwood City, California); Michael Thomas Bethune (Pasadena, California); David Baltimore (Pasadena, California); Kenan Christopher Garcia (Menlo Park, California) |
| ABSTRACT | Compositions and methods are provided for the identification of peptide sequences that are ligands for a T cell receptor (TCR) of interest, in a given MHC context. |
| FILED | Thursday, September 03, 2020 |
| APPL NO | 17/011899 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) Original (OR) Class G01N 2333/7051 (20130101) G01N 2333/70539 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125756 | Birnbaum et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Michael Edward Birnbaum (Stanford, California); Juan Luis Mendoza (Redwood City, California); Michael Thomas Bethune (Pasadena, California); David Baltimore (Pasadena, California); Kenan Christopher Garcia (Menlo Park, California) |
| ABSTRACT | Compositions and methods are provided for the identification of peptide sequences that are ligands for a T cell receptor (TCR) of interest, in a given MHC context. |
| FILED | Thursday, September 03, 2020 |
| APPL NO | 17/011911 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) Original (OR) Class G01N 2333/7051 (20130101) G01N 2333/70539 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125757 | Lee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | Frances Eun-Hyung Lee (Atlanta, Georgia); Ignacio Sanz (Atlanta, Georgia); Doan C. Nguyen (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to methods of culturing and characterizing antibody secreting cells. In certain embodiments, this disclosure relates to methods of isolating antibody secreting cells, e.g., long lived plasma cells, replicating the isolated cells in growth media disclosed herein, and determining the nucleic acids sequences in the cells that encode the produced antibodies. |
| FILED | Wednesday, May 30, 2018 |
| APPL NO | 15/992174 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/163 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) G01N 33/6854 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125844 | Shi et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Xinwei Shi (Mountain View, California); Brian A. Hargreaves (Menlo Park, California) |
| ABSTRACT | A method for magnetic resonance imaging reconstructs images that have reduced under-sampling artifacts from highly accelerated multi-spectral imaging acquisitions. The method includes performing by a magnetic resonance imaging (MRI) apparatus an accelerated multi-spectral imaging (MSI) acquisition within a field of view of the MRI apparatus, where the sampling trajectories of different spectral bins in the acquisition are different; and reconstructing bin images using neural network priors learned from training data as regularization to reduce under-sampling artifacts. |
| FILED | Tuesday, June 25, 2019 |
| APPL NO | 16/451396 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) Original (OR) Class G01R 33/5611 (20130101) G01R 33/56545 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125846 | Sandino et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Christopher Michael Sandino (Menlo Park, California); Shreyas S. Vasanawala (Stanford, California); Joseph Yitan Cheng (Santa Clara, California); Jiacheng Jason He (Mountain View, California) |
| ABSTRACT | A method is disclosed for phase contrast magnetic resonance imaging (MRI) comprising: acquiring phase contrast 3D spatiotemporal MRI image data; inputing the 3D spatiotemporal MRI image data to a three-dimensional spatiotemporal convolutional neural network to produce a phase unwrapping estimate; generating from the phase unwrapping estimate an integer number of wraps per pixel; and combining the integer number of wraps per pixel with the phase contrast 3D spatiotemporal MRI image data to produce final output. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 16/826157 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) G01R 33/56316 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125847 | Eck et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Brendan Eck (Cleveland Heights, Ohio); Jesse Hamilton (Cleveland Heights, Ohio); Nicole Seiberlich (Shaker Heights, Ohio); Mark Griswold (Shaker Heights, Ohio) |
| ABSTRACT | A method for magnetic resonance fingerprinting with out-of-view artifact suppression includes acquiring MRF data from a region of interest in a subject. The MRF data is acquired using a non-Cartesian, variable density sampling trajectory. The MRF data includes data from within a desired field-of-view and data from outside the desired field-of-view. The method also includes generating a set of coil images based on the MRF data with a field-of-view larger than the desired field-of-view, determining a noise covariance based on the MRF data from outside the desired field-of-view, generating a coil combined image using an adaptive coil combination determined based on the noise covariance, applying the adaptive coil combination to the MRF data to grid each frame of the MRF data and generate MRF data with out-of-view artifact suppression. The method also includes identifying at least one property of the MRF data and generating a report. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 16/858177 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/4824 (20130101) G01R 33/4828 (20130101) G01R 33/56545 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127175 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Ge Wang (Loudonville, New York); Wenxiang Cong (Albany, New York) |
| ABSTRACT | A machine-learning-based monochromatic CT image reconstruction method is described for quantitative CT imaging. The neural network is configured to learn a nonlinear mapping function from a training data set to map a CT image, which is reconstructed from a single spectral current-integrating projection data set, to monochromatic projections at a pre-specified energy level, realizing monochromatic CT imaging and overcoming beam hardening. An apparatus, method and/or system are configured to determine, by a trained artificial neural network (ANN), a monochromatic projection data set based, at least in part, on a measured CT image. The measured CT image may be reconstructed based, at least in part, on measured projection data. The measured projection data may be polychromatic. The apparatus, method and/or system may be further configured to reconstruct a monochromatic CT image based, at least in part, on the monochromatic projection data set. |
| FILED | Wednesday, September 26, 2018 |
| APPL NO | 16/647220 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) Image Data Processing or Generation, in General G06T 11/006 (20130101) Original (OR) Class G06T 2207/10081 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127501 | Parate et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lumme Health, Inc. (Dover, Delaware) |
| ASSIGNEE(S) | Lumme Health, Inc. (Dover, Delaware) |
| INVENTOR(S) | Abhinav Parate (Worcester, Massachusetts); Akshaya Shanmugam (Amherst, Massachusetts); Deepak Ganesan (Amherst, Massachusetts); Christopher Donovan Salthouse (Newton, Massachusetts); Sherry Ann McKee (Guilford, Connecticut) |
| ABSTRACT | Behavioral intervention improves the efficacy of treatments designed to encourage healthy behaviors such as smoking cessation, adherence to food regimen after surgeries, and avoiding overeating. Aspects of the present disclosure relate to a health monitoring system that leverages wearable sensors, mobile devices (e.g. smartphones), and computer-based servers to monitor the health of a user and provide intervention at opportune moments to encourage healthy behavior. This system provides a scalable and cost-efficient way for health care providers to monitor the behavior of many users and encourage healthy behavior as appropriate. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 15/692967 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/109 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) G16H 40/67 (20180101) Original (OR) Class G16H 50/20 (20180101) G16H 50/50 (20180101) G16H 80/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11128168 | Chakrabartty et al. |
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| FUNDED BY |
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| APPLICANT(S) | Shantanu Chakrabartty (St. Louis, Missouri); Yarub Alazzawi (St. Louis, Missouri); Kenji Aono (St. Louis, Missouri); Erica L. Scheller (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Shantanu Chakrabartty (St. Louis, Missouri); Yarub Alazzawi (St. Louis, Missouri); Kenji Aono (St. Louis, Missouri); Erica L. Scheller (St. Louis, Missouri) |
| ABSTRACT | A self-capacitance based remote power delivery device includes a modulating power source electrically coupled to a grounded substrate, an energy harvesting device coupled to the grounded substrate, and the substrate. The modulating power source is configured to be capacitively coupled to a self-capacitive body. The energy harvesting device configured to be capacitively coupled to the self-capacitive body, and the substrate is configured to be capacitively coupled to a portion of the self-capacitive body in direct contact with the substrate. |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 16/789007 |
| ART UNIT | 2836 — Electrical Circuits and Systems |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 50/05 (20160201) Original (OR) Class Transmission H04B 5/0012 (20130101) H04B 5/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11123042 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | The Government of the United States as Represented by the Secretary of the Army (Ft. Detrick, Maryland) |
| INVENTOR(S) | Shane B. Anderson (Salt Lake City, Utah); Lorne H. Blackbourne (Austin, Texas); Mariya Gusman (St. Louis, Missouri); Jose Salinas (Fort Sam Houston, Texas) |
| ABSTRACT | An embodiment of the invention provides a method to measure fluid within a body cavity where data is received with an interface (210), the data being received from an ultrasound transducer. A three-dimensional sonographic image is generated with an image generator (220) connected to the interface (210), the three-dimensional sonographic image being generated from the data from the ultrasound transducer. The body cavity is identified in the three-dimensional sonographic image with an image processor (230) connected to the image generator (220); and, an area of fluid in the body cavity in the three-dimensional sonographic image is identified with the image processor (230). The volume of the area of fluid is calculated using the three-dimensional sonographic image and a stacked crescents process, a spherical fill process, a convex hull process, and/or a triangulation process. |
| FILED | Thursday, August 10, 2017 |
| APPL NO | 16/315543 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/02007 (20130101) A61B 8/04 (20130101) A61B 8/06 (20130101) A61B 8/466 (20130101) A61B 8/483 (20130101) Original (OR) Class A61B 8/5223 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123128 | You et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Joon S You (Laguna Niguel, California); Brian Jet-Fei Wong (Irvine, California); Wesley Moy (Irvine, California) |
| ABSTRACT | A method of altering skin tissue includes creating an electrochemical reaction in the tissue, wherein the electrochemical reaction occurs while avoiding electro-thermal damage to the tissue. |
| FILED | Wednesday, February 21, 2018 |
| APPL NO | 15/900985 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/02 (20130101) A61B 18/00 (20130101) A61B 18/1206 (20130101) Original (OR) Class A61B 18/1477 (20130101) A61B 2018/0072 (20130101) A61B 2018/00452 (20130101) A61B 2018/00565 (20130101) A61B 2018/00714 (20130101) A61B 2018/00761 (20130101) A61B 2018/00827 (20130101) A61B 2018/00892 (20130101) A61B 2018/1425 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/328 (20130101) A61N 1/0502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123585 | Howland |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Glenn E. Howland (Acton, Maine) |
| ABSTRACT | An electrical safety system and method is provided which includes a flexible electrical safety vest, a lifeline coupled with the vest in various configurations, and leg straps. The electrical safety vest includes a number of loops which are used to couple the lifeline in a variety of relationships that enable different types of maneuvering of a worker with relation to a hazard. Various embodiments of the invention can be used to rapidly and safety remove a worker from proximity to an immediate threat to their life, health, or safety. Direct and indirect extraction from a danger are enabled. A variety of methods are also provided for operating various embodiments of the invention. |
| FILED | Saturday, December 29, 2018 |
| APPL NO | 16/236433 |
| ART UNIT | 3634 — Static Structures, Supports and Furniture |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 1/04 (20130101) A41D 13/0007 (20130101) A41D 13/008 (20130101) A41D 2600/20 (20130101) Devices, Apparatus or Methods for Life-saving A62B 35/0018 (20130101) Original (OR) Class A62B 35/0037 (20130101) A62B 35/0043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123590 | Bruno et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Ferdinando F Bruno (Reading, Massachusetts); Manuele Bernabei (Rome, Italy); LTC Andrea Chiappa (Rome, Italy); David Ziegler (Clinton, Massachusetts); Nicole F Farhadi (Plymouth, Massachusetts) |
| ABSTRACT | The disclosed subject matter relates to a method of treating of asbestos or asbestos-containing material, comprising applying to the asbestos or asbestos-containing material a composition including a treatment compound comprising at least one of hexafluoro titanium di-ammonium, potassium hexafluoro zirconate. ammonium hexafluoro phosphate. ammonium hexafluoro stannate, ammonium hexafluoro germanate, ammonium tetrafluoro borate or ammonium heptafluoro tantalite; and a fluorine scavenger compound. |
| FILED | Friday, July 12, 2019 |
| APPL NO | 16/509523 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/33 (20130101) Original (OR) Class A62D 2101/41 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3577 (20130101) G01N 2021/3595 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123937 | Ghebrebrhan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Natick, Massachusetts) |
| ASSIGNEE(S) | U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Michael Ghebrebrhan (Cambridge, Massachusetts); Landa Hoke (Leominster, Massachusetts) |
| ABSTRACT | Disclosed is a retro-reflective thread 100 including an internal section 10; a plurality of fibers 12, each fiber comprising a respective longitudinal axis and a respective surface and each fiber comprising a first material that is at least partially optically transmissive, and wherein said plurality of fibers are configured with their respective longitudinal axes substantially co-linearly aligned with one another and said plurality of fibers are interconnected in series around said internal section and wherein a first part 12b of said respective surface of each of said plurality of fibers faces into said internal section; and a reflective material 14 provided on said first part of said respective surface of each of said plurality of fibers. |
| FILED | Tuesday, August 20, 2019 |
| APPL NO | 16/544967 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Outerwear; Protective Garments; Accessories A41D 13/01 (20130101) Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00605 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/12 (20130101) B29K 2033/04 (20130101) B29K 2995/003 (20130101) B29K 2995/0026 (20130101) Chemical Features in the Manufacture of Artificial Filaments, Threads, Fibres, Bristles or Ribbons; Apparatus Specially Adapted for the Manufacture of Carbon Filaments D01F 6/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124057 | Avenatti et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Peter Matthew Avenatti (Bloomington, Indiana); Tyler Allen Mullis (Bloomfield, Indiana); Braden Matthew Yake (Bloomington, Indiana); Jason Everett Miller (Linton, Indiana); Ryan Wynne (Bloomington, Indiana); Lucas Allison (Bloomington, Indiana); Joseph Patrick Bailey (Bloomington, Indiana); Al Bodey (Charlotte, North Carolina) |
| ABSTRACT | The present invention relates to electric drivetrain kits for converting all-terrain vehicles into hybrid or electric vehicles. In exemplary embodiments, a conversion kit replaces an existing standard single motor and transmission drive system with a dual set-up including a motor for each rear wheel and a split transmission that houses two sets of gear reduction components in a single housing or an all-wheel configuration with two transmission sets (front and rear). Dual output shafts in each transmission set drive the wheels independently to provide the torque needed as required and demanded by each wheel. |
| FILED | Wednesday, February 20, 2019 |
| APPL NO | 16/280843 |
| ART UNIT | 3659 — Material and Article Handling |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 1/02 (20130101) B60K 6/40 (20130101) Original (OR) Class B60K 6/52 (20130101) Propulsion of Electrically-propelled Vehicles; Supplying Electric Power for Auxiliary Equipment of Electrically-propelled Vehicles; Electrodynamic Brake Systems for Vehicles in General; Magnetic Suspension or Levitation for Vehicles; Monitoring Operating Variables of Electrically-propelled Vehicles; Electric Safety Devices for Electrically-propelled Vehicles B60L 50/16 (20190201) B60L 2200/46 (20130101) Servicing, Cleaning, Repairing, Supporting, Lifting, or Manoeuvring of Vehicles, Not Otherwise Provided for B60S 11/00 (20130101) Conjoint Control of Vehicle Sub-units of Different Type or Different Function; Control Systems Specially Adapted for Hybrid Vehicles; Road Vehicle Drive Control Systems for Purposes Not Related to the Control of a Particular Sub-unit B60W 20/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124288 | Collmus et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The United States of America, as represted by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John P. Collmus (Camarillo, California); Nicholas J. Duckworth (Annapolis, Maryland); Scott M. Reider (Camarillo, California); Chong T. Oh (Camarillo, California) |
| ABSTRACT | The embodiments are directed to an interface mount between a vehicle steering/control device and a mobile computer protective case. The interface mount has two sides. One side of the interface mount is attached to the vehicle steering/control device. The other side of the interface mount is attached to an AMPS hole pattern plate. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/265217 |
| ART UNIT | 3647 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 13/0423 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124296 | Hefner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Levi Charles Hefner (Arlington, Texas); Dakota Charles Easley (Hurst, Texas) |
| ABSTRACT | An unmanned aircraft system includes a flying wing airframe having leading and trailing edges with respective sweep angles. A thrust array is coupled to the airframe and includes first and second motor mounts each rotatably coupled to the leading edge. Each motor mount has first and second propulsion assemblies coupled to respective first and second distal ends thereof. A power system is operably associated with the thrust array and is operable to provide power to each propulsion assembly. A flight control system is operably associated with the thrust array and is operable to independently control the speed of each propulsion assembly. In a flight configuration of the system, each motor mount is substantially perpendicular with the leading edge such that the thrust array forms a two-dimensional thrust array. In a compact storage configuration of the system, each motor mount is substantially parallel with the leading edge. |
| FILED | Tuesday, July 10, 2018 |
| APPL NO | 16/031741 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 29/02 (20130101) B64C 39/024 (20130101) Original (OR) Class B64C 2201/20 (20130101) B64C 2201/024 (20130101) B64C 2201/028 (20130101) B64C 2201/042 (20130101) B64C 2201/104 (20130101) B64C 2201/108 (20130101) B64C 2201/123 (20130101) B64C 2201/127 (20130101) B64C 2201/145 (20130101) B64C 2201/146 (20130101) Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 27/26 (20130101) B64D 31/06 (20130101) B64D 2027/262 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124782 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Lexington, Massachusetts); Alexis Christine Komor (San Diego, California) |
| ABSTRACT | Some aspects of this disclosure provide strategies, systems, reagents, methods, and kits that are useful for the targeted editing of nucleic acids, including editing a single site within the genome of a cell or subject, e.g., within the human genome. In some embodiments, fusion proteins of Cas9 and nucleic acid editing enzymes or enzyme domains, e.g., deaminase domains, are provided. In some embodiments, methods for targeted nucleic acid editing are provided. In some embodiments, reagents and kits for the generation of targeted nucleic acid editing proteins, e.g., fusion proteins of Cas9 and nucleic acid editing enzymes or domains, are provided. |
| FILED | Wednesday, April 03, 2019 |
| APPL NO | 16/374634 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/50 (20130101) A61K 38/465 (20130101) A61K 47/61 (20170801) Peptides C07K 2319/00 (20130101) C07K 2319/80 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 9/78 (20130101) C12N 9/6472 (20130101) C12N 15/01 (20130101) C12N 15/102 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/156 (20130101) Enzymes C12Y 301/00 (20130101) C12Y 301/22 (20130101) C12Y 304/22062 (20130101) C12Y 305/04 (20130101) C12Y 305/04001 (20130101) C12Y 305/04004 (20130101) C12Y 305/04005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124830 | Lan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regent of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Freeman Lan (San Francisco, California); Benjamin Demaree (Berkeley, California); Iain Clark (San Francisco, California); Adam R. Abate (Daly City, California) |
| ABSTRACT | The present disclosure provides ultrahigh-throughput single cell genomic sequencing methods, referred to herein as “SiC-seq”, which methods include encapsulating single cells in molten gel droplets to facilitate bulk cell lysis and purification of genomic DNA in microgels. Systems and devices for practicing the subject methods are also provided. |
| FILED | Wednesday, April 15, 2020 |
| APPL NO | 16/849344 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 2565/629 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124846 | Green et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Alexander A. Green (Scottsdale, Arizona); Peng Yin (Brookline, Massachusetts); James J. Collins (Newton, Massachusetts); Jongmin Kim (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides novel and versatile classes of riboregulators, including inter alia activating and repressing riboregulators, switches, and trigger and sink RNA, and methods of their use for detecting RNAs in a sample such as a well and in modulating protein synthesis and expression. |
| FILED | Tuesday, July 14, 2015 |
| APPL NO | 15/326054 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1138 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125158 | Bouldin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| INVENTOR(S) | Bruce Dan Bouldin (Phoenix, Arizona); Derek Anthony Rice (Phoenix, Arizona); Michael Todd Barton (Phoenix, Arizona); Raymond Mccage (Chandler, Arizona); Yates Wong (Humboldt, Arizona); Kevin Sing (Mesa, Arizona) |
| ABSTRACT | A system for delivering a flow stream of a gas to a compressor. A shroud extends from an inlet to the compressor and defines a main inlet passage configured to direct the flow stream from the inlet to the compressor. A communication plenum is separated from the main inlet passage. A port system includes first and second port subsystems that each provide an opening between the main inlet passage and the communication plenum. The first port subsystem is disposed further from the compressor than the second port subsystem. The port system is configured so that a portion of the gas enters or exits the compressor through the second port subsystem, depending on operating conditions of the compressor. |
| FILED | Monday, September 17, 2018 |
| APPL NO | 16/132954 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/02 (20130101) B64D 2033/0233 (20130101) B64D 2033/0293 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 1/14 (20130101) F01D 25/02 (20130101) F01D 25/10 (20130101) F01D 25/14 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/06 (20130101) F02C 6/206 (20130101) F02C 7/04 (20130101) F02C 7/047 (20130101) F02C 7/057 (20130101) Original (OR) Class F02C 9/18 (20130101) Non-positive-displacement Pumps F04D 27/023 (20130101) F04D 27/0238 (20130101) F04D 29/5853 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2250/51 (20130101) F05D 2250/73 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125187 | Filipenco |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | RAYTHEON TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| INVENTOR(S) | Victor G. Filipenco (Portland, Connecticut) |
| ABSTRACT | A gas turbine engine includes a case assembly, a splitter, an upstream blade row, and a transition duct. The case assembly defines an outer flow path wall and an inner flow path wall. The splitter is disposed between the outer flow path wall and the inner flow path wall. The splitter has a first surface and a second surface disposed opposite the first surface. The transition duct is defined by the outer flow path and the inner flow path and extends between the upstream blade row and the leading edge of the splitter. |
| FILED | Wednesday, August 01, 2018 |
| APPL NO | 16/052022 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 3/13 (20130101) F02C 9/18 (20130101) Jet-propulsion Plants F02K 3/06 (20130101) F02K 3/075 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/36 (20130101) F05D 2240/12 (20130101) F05D 2260/606 (20130101) F05D 2270/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125352 | Reynoso |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Bryan Reynoso (Ponte Vedra Beach, Florida) |
| ABSTRACT | A magnetically actuated fluid control valve has an internal flooding chamber, an internal piston chamber and a fluid inlet and outlet. The fluid inlet and outlet are in fluid communication with the flooding chamber. A piston is movable within the piston chamber and the flooding chamber. The piston is movable to a closed position wherein fluid cannot flow through the valve, and an open position wherein fluid can flow through the valve. The valve body and piston are fitted with electromechanical and permanent magnets, respectively. Selective electrical excitation of the electromechanical magnets on the valve body cause them to attract or repel the permanent magnets on the piston, causing the piston to move to either the open or closed position. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 16/778571 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Valves; Taps; Cocks; Actuating-floats; Devices for Venting or Aerating F16K 31/082 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125545 | Shaw et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | U.S. Government as Represented by the Secretary of the Army (Dover, New Jersey) |
| ASSIGNEE(S) | U.S. Government as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Anthony P. Shaw (Madison, New Jersey); Jay C. Poret (Sparta, New Jersey); Lori J. Groven (Rapid City, South Dakota); Joshua Koenig (Rapid City, South Dakota); Jason Brusnahan (Semaphore Park, Australia) |
| ABSTRACT | The present invention is a pyrotechnic time delay system that is improved over prior-art designs. Specifically, the system described herein comprises at least one delay element. The delay element or delay dements each have an input charge, a delay composition, and an output charge. Both the input charge and the output charge are igniter compositions and are comprised of the same components despite having different functional goals. The input charge and output charge compositions preferably contain titanium, manganese dioxide, and polytetrafluoroethylene. The delay composition may be modified from current formulations to include manganese and manganese dioxide, or tungsten and manganese dioxide. The system disclosed herein may be comprised of one delay element, or it may be modular wherein multiple delay elements are connected in series. |
| FILED | Thursday, February 08, 2018 |
| APPL NO | 15/891557 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 23/00 (20130101) C06B 33/00 (20130101) Detonating or Priming Devices; Fuses; Chemical Lighters; Pyrophoric Compositions C06C 5/00 (20130101) Ammunition Fuzes; Arming or Safety Means Therefor F42C 9/10 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125689 | Meyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jerry R. Meyer (Catonsville, Maryland); Igor Vurgaftman (Severna Park, Maryland); Chadwick Lawrence Canedy (Washington, District of Columbia); William W. Bewley (Falls Church, Virginia); Chul Soo Kim (Springfield, Virginia); Charles D. Merritt (Fairfax, Virginia); Michael V. Warren (Arlington, Virginia); R. Joseph Weiblen (Washington, District of Columbia); Mijin Kim (Springfield, Virginia) |
| ABSTRACT | Building blocks are provided for on-chip chemical sensors and other highly-compact photonic integrated circuits combining interband or quantum cascade lasers and detectors with passive waveguides and other components integrated on a III-V or silicon. A MWIR or LWIR laser source is evanescently coupled into a passive extended or resonant-cavity waveguide that provides evanescent coupling to a sample gas (or liquid) for spectroscopic chemical sensing. In the case of an ICL, the uppermost layer of this passive waveguide has a relatively high index of refraction that enables it to form the core of the waveguide, while the ambient air, consisting of the sample gas, functions as the top cladding layer. A fraction of the propagating light beam is absorbed by the sample gas if it contains a chemical species having a fingerprint absorption feature within the spectral linewidth of the laser emission. |
| FILED | Friday, July 12, 2019 |
| APPL NO | 16/509613 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/1895 (20130101) G01J 3/2803 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/27 (20130101) G01N 21/59 (20130101) Original (OR) Class G01N 21/255 (20130101) G01N 2201/0612 (20130101) Optical Elements, Systems, or Apparatus G02B 6/102 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/062 (20130101) H01S 5/101 (20130101) H01S 5/125 (20130101) H01S 5/0215 (20130101) H01S 5/0262 (20130101) H01S 5/0287 (20130101) H01S 5/343 (20130101) H01S 5/0421 (20130101) H01S 5/0612 (20130101) H01S 5/2063 (20130101) H01S 5/2206 (20130101) H01S 5/3402 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125723 | Dogaru et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Southwest Research Institute (San Antonio, Texas) |
| ASSIGNEE(S) | Southwest Research Institute (San Antonio, Texas) |
| INVENTOR(S) | Teodor Dogaru (San Antonio, Texas); Clinton J. Thwing (Bulverde, Texas); Darryl Wagar (San Antonio, Texas) |
| ABSTRACT | A method of testing the residual stress around a cold-worked hole in a test material. The test uses two identical eddy current coil pairs, each pair having a driving coil and a pickup coil. One coil pair is placed into the cold-worked hole. The other coil pair is placed into a non-cold worked hole in a reference material. When the coils are activated, and with a properly chosen phase difference between the excitation signal and the output signal, the in-phase component of the output voltage signal can be correlated to residual stress around the cold-worked hole. |
| FILED | Tuesday, January 28, 2020 |
| APPL NO | 16/774119 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 7/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/904 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125748 | Gopinath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); UNIVERSITY OF BRITISH COLUMBIA (Vancouver, Canada) |
| ASSIGNEE(S) | UNIVERSITY OF BRITISH COLUMBIA (Vancouver, Canada); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Ashwin Gopinath (Cambridge, Massachusetts); Christopher Thachuk (Seattle, Washington); David G. Kirkpatrick (Vancouver, Canada); Paul W. Rothemund (Pasadena, California) |
| ABSTRACT | According to one embodiment of the present invention, a structure includes: a substrate having a patterned surface of one or more binding sites; and a molecular shape made by a polynucleotide platform having a shape corresponding to a shape of a binding site of the one or more binding sites, the molecular shape being bound to one of the one or more binding sites. |
| FILED | Tuesday, September 04, 2018 |
| APPL NO | 16/121603 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6445 (20130101) G01N 33/548 (20130101) Original (OR) Class G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125772 | Mitchell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bliley Technologies, Inc. (Erie, Pennsylvania) |
| ASSIGNEE(S) | BLILEY TECHNOLOGIES, INC. (Erie, Pennsylvania) |
| INVENTOR(S) | Jay Mitchell (Ypsilanti, Michigan); Anthony Challoner (Manhattan Beach, California); Sangwoo Lee (Ann Arbor, Michigan) |
| ABSTRACT | Motion and/or orientation sensing systems can utilize gyroscopes, accelerometers, magnetometers, and other sensors for measuring motion or orientation of connected objects. Temperature changes affect the precision of the data output by the motion/orientation sensing device. A system is provided for controllably heating a device within a package to a desired temperature that varies based on the ambient temperature. The operating temperature of the device can then be known and controlled. The ambient temperature can be known through an ambient temperature sensor, for example. Given this information, a controller compensates the data output by the device to further improve the accuracy in the measurements. Like the amount of heating provided to the package, the amount of compensation is also based on the ambient temperature and/or the device temperature. |
| FILED | Tuesday, July 02, 2019 |
| APPL NO | 16/459775 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/0096 (20130101) B81B 2201/0235 (20130101) B81B 2201/0242 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 25/005 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 13/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 21/00 (20130101) Original (OR) Class G01P 2015/0871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125865 | Hopper et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Woolpert, Inc. (Dayton, Ohio) |
| ASSIGNEE(S) | Woolpert, Inc. (Dayton, Ohio) |
| INVENTOR(S) | Nathan Lee Hopper (Diamondhead, Mississippi); Joseph R. Seppi (McLean, Virginia); Rodney Ross Faulkner, II (Diamondhead, Mississippi); Mark Douglas Smits, II (Diamondhead, Mississippi); JoongYong Park (Slidell, Louisiana); Mark Stephen Millman (Anacortes, Washington); Eric Josef Cahoon (Woodbridge, Virginia); Christopher T. Cotton (Honeoye Falls, New York); Joshua Gluckman (Columbia, Maryland); Alexander Cheff Halterman (San Diego, California); Grady Tuell (Madison, Georgia); Andrew Wallace Stark (New Orleans, Louisiana); John Henry Gerhard (Littleton, Colorado); William Jeffrey Lillycrop (Gulf Breeze, Florida) |
| ABSTRACT | Airborne LiDAR bathymetry systems and methods of use are provided. The airborne LiDAR bathymetry system can collect topographic data and bathymetric data at high altitudes. The airborne LiDAR bathymetry system has a receiver system, a detector system, and a laser transmission system. |
| FILED | Monday, June 01, 2020 |
| APPL NO | 16/889087 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/02 (20130101) B64C 2201/123 (20130101) Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/51 (20130101) Original (OR) Class G01S 7/4808 (20130101) G01S 7/4816 (20130101) G01S 7/4863 (20130101) G01S 17/89 (20130101) G01S 2205/03 (20200501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125896 | Inglis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SILVERSIDE DETECTORS INC. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Silverside Detectors Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Andrew Inglis (Brookline, Massachusetts); Alison Forsyth (Somerville, Massachusetts); Thomas Nadovich (Somerville, Massachusetts); Timothy Teal (Brighton, Massachusetts); Philip Taber (Arlington, Massachusetts); Hidefumi Tomita (Pittsburgh, Pennsylvania) |
| ABSTRACT | A narrow thermal neutron detector includes a slidably receivable ionization thermal neutron detector module within an overall housing body. An active sheet layer of the ionization thermal neutron detector module can be tensioned across its width. The ionization thermal neutron detector module can include module upper major surface extents and module lower surface extents such that, when installed within the housing body, the module upper major surface extents are in a first spaced apart confronting relationship with housing upper major surface extents to define a first clearance and module lower major surface extents are in a second spaced apart confronting relationship with housing lower major surface extents to define a second clearance to accommodate housing flexing due to ambient pressure change. The housing body can be formed with a single opening for receiving the ionization thermal neutron detection module or with opposing first and second opposing end openings. |
| FILED | Wednesday, February 26, 2020 |
| APPL NO | 16/801147 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Nuclear or X-radiation G01T 3/00 (20130101) G01T 3/008 (20130101) Original (OR) Class Electric Discharge Tubes or Discharge Lamps H01J 47/02 (20130101) H01J 47/12 (20130101) H01J 47/1205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125936 | Miller |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gary A. Miller (Alexandria, Virginia) |
| ABSTRACT | An embodiment of the indention includes a passive, fiber optic, thermal insulator. The thermal insulator includes an inner sleeve defining a central access port. The thermal insulator includes an outer sleeve concentric to the inner sleeve. The inner sleeve and the outer sleeve are joined sufficient to define an annular void. The thermal insulator includes a first insulator located in the annular void. Optionally, the apparatus includes at least one optical fiber secured in the central access port. |
| FILED | Tuesday, February 26, 2019 |
| APPL NO | 16/285329 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/0218 (20130101) Original (OR) Class G02B 6/0219 (20130101) G02B 6/4236 (20130101) G02B 6/29317 (20130101) G02B 6/29398 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11126063 | Meissner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Helmuth Ernst Meissner (Pleasanton, California); Huai-Chuan Lee (Albany, California); David Joseph Meissner (San Ramon, California); Da Li (San Ramon, California) |
| ASSIGNEE(S) | Onyx Optics, Inc. (Dublin, California) |
| INVENTOR(S) | Helmuth Ernst Meissner (Pleasanton, California); Huai-Chuan Lee (Albany, California); David Joseph Meissner (San Ramon, California); Da Li (San Ramon, California) |
| ABSTRACT | A nonlinear optical crystal (NLO) with a phase matching angle that is corrected with a source laser beam for harmonic conversion. The source laser only has to be within a wavelength range depending on the dispersion of the crystal while the crystal is tilted to the calculated expected conversion angle of the source laser as reference. The angle correction is accomplished with a parallel kinematic motion device to which a nonlinear crystal is mounted on a platform, to determine the wavelength- and temperature-specific angle with active laser alignment and subsequent precision resurfacing. The invented phase matching angle correction is applicable to any uniaxial and biaxial NLO crystals in a wide range of wavelengths, e.g., from far ultraviolet to visible to far infrared. It is of most value for NLO crystals of large walk-off and is applicable to any prior art frequency converting architectures. |
| FILED | Thursday, November 07, 2019 |
| APPL NO | 16/676969 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/3544 (20130101) Original (OR) Class G02F 1/3551 (20130101) G02F 2203/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11126403 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Jianhua Yang (Hadley, Massachusetts); Qiangfei Xia (Amherst, Massachusetts); Hao Jiang (Sunderland, Massachusetts) |
| ABSTRACT | A true random number generator device based on a diffusive memristor is disclosed. The random number generator device includes a diffusive memristor driven by a pulse generator circuit. The diffusive memristor produces a stochastically switched output signal. A comparator circuit receives the stochastically switched output signal from the diffusive memristor and generates an output signal having a random pulse width. An AND gate logic circuit is driven by a clock signal and the output signal from the comparator circuit. The AND gate logic circuit produces a combined output signal. A counter circuit receives the combined output signal from the AND gate logic circuit and generates a random bit string output signal. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 16/367623 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 7/588 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/085 (20130101) H01L 45/146 (20130101) H01L 45/1253 (20130101) H01L 45/1266 (20130101) Pulse Technique H03K 3/84 (20130101) H03K 19/20 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0869 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11126550 | Yeung et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland at College Park (College Park, Maryland); Crossbar, Inc. (Santa Clara, California) |
| ASSIGNEE(S) | Crossbar, Inc (Santa Clara, California) |
| INVENTOR(S) | Donald Yeung (Bethesda, Maryland); Bruce L. Jacob (Annapolis, Maryland); Mehdi Asnaashari (Danville, California); Sylvain Dubois (San Francisco, California) |
| ABSTRACT | Disclosed is a monolithic integrated circuit (IC) computing device with multiple independent process cores (multicore) and embedded, non-volatile resistive memory serving as system memory. The resistive system memory is fabricated above the substrate, and logic circuits embodying the process cores are fabricated on the substrate. In addition, access circuitry for operating on the resistive system memory, and circuitry embodying memory controllers, routing devices and other logic components is provided at least in part on the substrate. Large main memory capacities of tens or hundreds of gigabytes (GB) are provided and operable with many process cores, all on a single die. This monolithic integration provides close physical proximity between the process cores and main memory, facilitating significant memory parallelism, reduced power consumption, and eliminating off-chip main memory access requests. |
| FILED | Tuesday, September 04, 2018 |
| APPL NO | 16/121339 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 12/0802 (20130101) Original (OR) Class G06F 2212/1021 (20130101) Static Stores G11C 13/003 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/2463 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11126595 | Medard et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Muriel Medard (Belmont, Massachusetts); Ulric J. Ferner (Cambridge, Massachusetts); Tong Wang (Cambridge, Massachusetts) |
| ABSTRACT | Multi-resolution encoded files are stored on a plurality of disk drives using systematic network coded storage. In some embodiments, the stored files are used to provide video streaming services for users. |
| FILED | Tuesday, September 10, 2019 |
| APPL NO | 16/565724 |
| ART UNIT | 2159 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/1827 (20190101) Original (OR) Class Pictorial Communication, e.g Television H04N 21/2312 (20130101) H04N 21/23439 (20130101) H04N 21/234327 (20130101) H04N 21/234363 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11126905 | Zajic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Alenka Zajic (Atlanta, Georgia); Chia-Lin Cheng (Atlanta, Georgia); Luong N. Nguyen (Atlanta, Georgia); Milos Z. Prvulovic (Atlanta, Georgia) |
| ABSTRACT | A semi-passive radio frequency identification (RFID) tag includes a digital circuit with switching components operating within an interrogation range of an incident carrier wave. A plurality of input connections and output connections direct data communications through the switching components within the digital circuit, and the data communications are subject to switching operations of the switching components between at least one of the input connections and at least one of the output connections. A backscatter response reflected from the digital circuit upon arrival of the incident carrier wave, wherein the backscatter response is a modulated backscatter response in the presence of the switching operations. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 16/685521 |
| ART UNIT | 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/0008 (20130101) G06K 7/10356 (20130101) G06K 19/0723 (20130101) Original (OR) Class G06K 19/07749 (20130101) Transmission H04B 5/0062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127231 | Steinert |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Alan H. Steinert (Fort Worth, Texas) |
| ABSTRACT | A system and algorithm-based method of determining engine health and assuring available propulsion power based on historical data reflecting the individual engine's unique performance “fingerprint.” |
| FILED | Thursday, April 11, 2019 |
| APPL NO | 16/381416 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 45/00 (20130101) B64D 2045/0085 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 23/0221 (20130101) G05B 23/0243 (20130101) Electric Digital Data Processing G06F 7/08 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 5/008 (20130101) G07C 5/085 (20130101) Original (OR) Class G07C 5/0808 (20130101) G07C 5/0816 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127715 | Andry et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Paul S. Andry (Yorktown Heights, New York); Mark D. Schultz (Ossining, New York); Cornelia K. Tsang (Mohegan Lake, New York) |
| ABSTRACT | An electrical device that includes at least two active wafers having at least one through silicon via, and at least one unitary electrical communication and spacer structure present between a set of adjacently stacked active wafers of the at least two active wafers. The unitary electrical communication and spacer structure including an electrically conductive material core providing electrical communication to the at least one through silicon via structure in the set of adjacently stacked active wafers and a substrate material outer layer. The at least one unitary electrical communication and spacer structure being separate from and engaged to the adjacently stacked active wafers, wherein coolant passages are defined between surfaces of the adjacently stacked active wafers and the at least one unitary electrical communication and spacer structure. |
| FILED | Thursday, January 03, 2019 |
| APPL NO | 16/238803 |
| ART UNIT | 2892 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 23/473 (20130101) H01L 23/481 (20130101) H01L 24/16 (20130101) H01L 24/32 (20130101) H01L 24/73 (20130101) H01L 24/81 (20130101) H01L 24/94 (20130101) H01L 25/50 (20130101) H01L 25/0657 (20130101) Original (OR) Class H01L 2224/81 (20130101) H01L 2224/94 (20130101) H01L 2224/94 (20130101) H01L 2224/131 (20130101) H01L 2224/131 (20130101) H01L 2224/291 (20130101) H01L 2224/291 (20130101) H01L 2224/16146 (20130101) H01L 2224/32225 (20130101) H01L 2224/73203 (20130101) H01L 2224/81005 (20130101) H01L 2225/06513 (20130101) H01L 2225/06541 (20130101) H01L 2225/06589 (20130101) H01L 2924/00 (20130101) H01L 2924/0002 (20130101) H01L 2924/0002 (20130101) H01L 2924/014 (20130101) H01L 2924/014 (20130101) H01L 2924/1305 (20130101) H01L 2924/1431 (20130101) H01L 2924/1434 (20130101) H01L 2924/1435 (20130101) H01L 2924/1436 (20130101) H01L 2924/1438 (20130101) H01L 2924/10252 (20130101) H01L 2924/10253 (20130101) H01L 2924/10271 (20130101) H01L 2924/10272 (20130101) H01L 2924/10329 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127966 | Arugula et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CFD Research Corporation (Huntsville, Alabama) |
| ASSIGNEE(S) | CFD Research Corporation (Huntsville, Alabama) |
| INVENTOR(S) | Mary Arugula (Huntsville, Alabama); Erica Wagner Pinchon (Huntsville, Alabama); Sameer Singhal (Huntsville, Alabama); Yevgenia Ulyanova (Huntsville, Alabama) |
| ABSTRACT | A cathode can include: an electrode substrate; a porphyrin precursor attached to the substrate; and an enzyme coupled to the electrode substrate to be associated with the porphyrin precursor, the enzyme reduces oxygen. The cathode can include a conductive material associated with the porphyrin precursor and/or the enzyme. The cathode can include 1-pyrenebutanoic acid, succinimidyl ester (PBSE) associated with the porphyrin precursor and/or the enzyme and/or the conductive material. The cathode can include 2,5-dimethyl-1-phenyl-1H-pyrrole-3-carbaldehyde (DMY-Carb) associated with the 1-pyrenebutanoic acid, succinimidyl ester (PBSE) and/or the porphyrin precursor and/or the enzyme and/or the conductive material. The porphyrin precursor is attached to the substrate through covalent coupling. In some aspects, substrate is linked to the porphyrin precursor, the porphyrin precursor is linked to the conductive material, the conductive material is linked to the PBSE, the PBSE is linked to the DMY-carb, and the DMY-carb is linked to the enzyme. |
| FILED | Monday, February 04, 2019 |
| APPL NO | 16/266950 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 11/14 (20130101) Enzymes C12Y 101/01001 (20130101) C12Y 101/01002 (20130101) C12Y 101/99035 (20130101) C12Y 102/02001 (20130101) C12Y 102/03004 (20130101) C12Y 103/03005 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/90 (20130101) H01M 4/92 (20130101) H01M 4/96 (20130101) H01M 4/622 (20130101) H01M 4/663 (20130101) H01M 4/9008 (20130101) H01M 8/16 (20130101) Original (OR) Class H01M 8/1007 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11128039 | Lavin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Ronald O. Lavin (Gilbert, Arizona); Dennis K. McCarthy (Gilbert, Arizona); Andy H. Lee (Phoenix, Arizona); Manny S. Urcia (Wildwood, Missouri) |
| ABSTRACT | A method for designing an antenna including defining an operating frequency of an antenna radiating element located within an antenna cavity structure; determining a non-loaded depth of the antenna cavity structure; determining a reduced depth of the antenna cavity structure; determining a reduction factor to reduce the non-loaded depth to the reduced depth; and selecting a dielectric material, at least partially forming a radome structure covering the antenna radiating element, to achieve the reduction factor. |
| FILED | Wednesday, April 01, 2020 |
| APPL NO | 16/837281 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/42 (20130101) H01Q 1/422 (20130101) Original (OR) Class H01Q 7/00 (20130101) H01Q 9/0485 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11128082 | Wise et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Blink Astro, LLC (Atlanta, Georgia) |
| ASSIGNEE(S) | Blink Astro, LLC (Atlanta, Georgia) |
| INVENTOR(S) | Evan Shelby Wise (Atlanta, Georgia); John Terrell Madigan (Atlanta, Georgia); William Carlton Doncaster (Atlanta, Georgia); Kevin Marcus Feld (Atlanta, Georgia); Jon Grant Wallace (Atlanta, Georgia); Matthew David Arceri (Atlanta, Georgia); Wahaj Umar Khan (Atlanta, Georgia) |
| ABSTRACT | Androgynous modular connectors (e.g., modular spacecraft connectors) are disclosed herein. The modular connectors can include prismatic-shaped body with side panels, a base, and a face panel. The face panel can include three or more sides that define an opening. A claw assembly can be housed within the prismatic-shaped body. The claw assembly can include two or more extendable arms. A motor can be housed within the prismatic-shaped body. The motor can be operatively connected to the claw assembly. The motor can be configured to extend and retract the claw assembly. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 16/586232 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/64 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/70 (20130101) H01R 13/514 (20130101) Original (OR) Class H01R 13/6273 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11128479 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AZ Board of Regents on Behalf of AZ State Univ (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Yanchao Zhang (Phoenix, Arizona); Xin Yao (Changsha, China PRC) |
| ABSTRACT | A system for a social media data provider to provide verification of a social media data query-result. The system receives a social media dataset from a social media network operator, receives a query about the social media dataset from a social media data consumer, queries the social media dataset based on the query and generate the query-result based thereon, generates verification information by which the social media data consumer is to verify a trustworthiness of the query-result, and provides the query-result and the verification information to the social media data consumer. |
| FILED | Friday, April 26, 2019 |
| APPL NO | 16/396550 |
| ART UNIT | 2431 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9024 (20190101) G06F 16/9536 (20190101) G06F 21/602 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3271 (20130101) Original (OR) Class H04L 2209/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11128935 | Li |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BTS Software Solutions, LLC (Columbia, Maryland) |
| ASSIGNEE(S) | BTS Software Solutions, LLC (Columbia, Maryland) |
| INVENTOR(S) | Dunling Li (Rockville, Maryland) |
| ABSTRACT | Methods and systems for processing telemetry data that contains multiple data types is disclosed. Optimum multimodal encoding approaches can be used which can achieve data-specific compression performance for heterogeneous datasets by distinguishing data types and their characteristics at real-time and applying most effective compression method to a given data type. Using an optimum encoding diagram for heterogeneous data, a data classification algorithm classifies input data blocks into predefined categories, such as Unicode, telemetry, RCS and IR for telemetry datasets, and a class of unknown which includes non-studied data types, and then assigns them into corresponding compression models. |
| FILED | Friday, June 28, 2019 |
| APPL NO | 16/457903 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 9/00 (20130101) G06T 9/001 (20130101) Coding; Decoding; Code Conversion in General H03M 7/30 (20130101) Pictorial Communication, e.g Television H04N 19/12 (20141101) H04N 19/20 (20141101) H04N 19/46 (20141101) H04N 19/50 (20141101) H04N 19/88 (20141101) H04N 19/119 (20141101) H04N 19/174 (20141101) Selecting H04Q 9/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11122796 | Manuchehrabadi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Navid Manuchehrabadi (Minneapolis, Minnesota); Meng Shi (Xi'an, China PRC); Feng Xu (Xi'an, China PRC); T J Lu (Xi'an, China PRC); John Bischof (St. Paul, Minnesota) |
| ABSTRACT | Compositions and methods for cryoprotecting a biological tissue can involve a cryoprotective agent and a metal component that includes a metal foam, a metal foil, or a metal seed. The method allows the biological tissue to be rewarmed at a rate of at least 100° C./min. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/999315 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0268 (20130101) Original (OR) Class A01N 1/0284 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11122965 | Valdastri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Pietro Valdastri (Leeds, United Kingdom); Piotr R. Slawinski (Lincoln, Nebraska); Addisu Z. Taddese (Nashville, Tennessee); Keith L. Obstein (Nashville, Tennessee) |
| ABSTRACT | Systems and methods are presented for localization of a capsule based on magnetic fields. The capsule is positioned in a magnetic field generated by a first magnet and an electromagnetic coil is operated to generate a sinusoidal magnetic field with a magnetic moment orthogonal to the magnetic moment of the first magnet. An average signal measurement calculated for each magnetic field sensor is defined as the magnetic field applied to the magnetic field sensor by the first magnet and used as an offset to determine the magnetic field applied by the electromagnetic coil. The pose of the capsule is then determined based at least in part on a combination of magnetic field signals applied by the electromagnetic coil to each of the magnetic field sensors. |
| FILED | Tuesday, October 09, 2018 |
| APPL NO | 16/155637 |
| ART UNIT | 3795 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/0008 (20130101) A61B 1/018 (20130101) A61B 1/041 (20130101) A61B 1/00149 (20130101) A61B 1/00158 (20130101) Original (OR) Class A61B 5/062 (20130101) A61B 5/6861 (20130101) A61B 34/73 (20160201) A61B 2034/731 (20160201) A61B 2034/2048 (20160201) A61B 2034/2051 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123297 | Weitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David A. Weitz (Bolton, Massachusetts); Alireza Abbaspourrad (Ithaca, New York); Jing Fan (Cambridge, Massachusetts); Weixia Zhang (Arlington, Massachusetts) |
| ABSTRACT | The present invention generally relates to microfluidic droplets and, in particular, to multiple emulsion microfluidic droplets. In certain aspects, particles such as gel particles can be prepared in an aqueous carrier from aqueous droplets (or a non-aqueous carrier from non-aqueous droplets). For example, in some embodiments, double-emulsion droplets of a first fluid, surrounded by a second fluid, contained in a carrier fluid may be prepared, where the first fluid forms a gel and the second fluid is removed. For instance, the second fluid may be dissolved in the carrier fluid, or the second fluid may be hardened, then removed, for example, due to a change in pH. Other embodiments of the present invention are generally directed to kits containing such microfluidic droplets, microfluidic devices for making such microfluidic droplets, or the like. |
| FILED | Wednesday, October 12, 2016 |
| APPL NO | 15/768135 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/044 (20130101) A61K 8/86 (20130101) A61K 8/87 (20130101) A61K 9/113 (20130101) A61K 9/1635 (20130101) A61K 9/1682 (20130101) Original (OR) Class A61K 9/5026 (20130101) A61K 9/5089 (20130101) A61K 47/60 (20170801) A61K 47/549 (20170801) A61K 47/6903 (20170801) A61K 47/6921 (20170801) A61K 2800/10 (20130101) A61K 2800/81 (20130101) A61K 2800/95 (20130101) A61K 2800/412 (20130101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 19/00 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/14 (20130101) B01J 13/20 (20130101) B01J 13/0065 (20130101) B01J 13/0069 (20130101) B01J 2219/00177 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123465 | Gogotsi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DREXEL UNIVERSITY (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Drexel University (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Yury Gogotsi (Warminster, Pennsylvania); Vadym Mochalin (Rolla, Missouri); Nicholas Pescatore (Ambler, Pennsylvania) |
| ABSTRACT | The present disclosure is directed to methods of removing proteins, including cytokines, from blood and blood products, the methods comprising contacting the blood or blood product with a form of carbon having high graphitic contents and slit-shaped mesopores and macropores, the pore size dimensions chosen to be comparable to the size of the proteins, wherein the contacting results in the removal of high levels of the protein from the blood or blood product in minutes or hours. |
| FILED | Friday, May 26, 2017 |
| APPL NO | 16/303687 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3486 (20140204) Original (OR) Class A61M 2202/07 (20130101) A61M 2202/0445 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/205 (20130101) B01J 20/321 (20130101) B01J 20/28083 (20130101) B01J 20/28085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123711 | Crocker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| INVENTOR(S) | Mark Crocker (Lexington, Kentucky); Yang Vanessa Song (Lexington, Kentucky); Justin Mobley (Lexington, Kentucky) |
| ABSTRACT | The invention herein concerns a catalyst of gold particles on a layered double hydroxide (LDH) that assists in oxidation of alcohols in lignins. In some embodiments, the LDH comprises lithium and aluminum metals. Also considered are methods of using the catalyst to oxidize lignins and methods of preparing the catalyst. |
| FILED | Friday, December 28, 2018 |
| APPL NO | 16/234950 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/04 (20130101) B01J 23/52 (20130101) Original (OR) Class B01J 27/236 (20130101) B01J 35/006 (20130101) B01J 35/0013 (20130101) B01J 35/0066 (20130101) B01J 37/08 (20130101) B01J 37/30 (20130101) B01J 37/031 (20130101) B01J 37/036 (20130101) B01J 37/0201 (20130101) Compounds of Unknown Constitution C07G 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123734 | Tse et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CytoVale Inc. (San Francisco, California) |
| ASSIGNEE(S) | CytoVale Inc. (San Francisco, California) |
| INVENTOR(S) | Henry Tat Kwong Tse (San Francisco, California); Ajay M. Shah (San Francisco, California); Lionel Guillou (San Francisco, California); Roya Sheybani (San Francisco, California); Christopher Dahlberg (San Francisco, California); Anne E. Jensen (San Francisco, California) |
| ABSTRACT | A system and method for determining a trajectory parameter of particles, comprising receiving a plurality of particles at a microfluidic channel, applying a force to each particle of the microfluidic channel, acquiring a dataset of each particle, measuring a trajectory of the particle, and determining a trajectory parameter of the particles. |
| FILED | Thursday, July 30, 2020 |
| APPL NO | 16/943716 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502746 (20130101) B01L 3/502753 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 2200/12 (20130101) B01L 2200/0631 (20130101) B01L 2200/0652 (20130101) B01L 2200/0668 (20130101) B01L 2200/0684 (20130101) B01L 2200/0694 (20130101) B01L 2300/185 (20130101) B01L 2300/0877 (20130101) B01L 2300/0887 (20130101) B01L 2400/0409 (20130101) B01L 2400/0415 (20130101) B01L 2400/0436 (20130101) Computer Systems Based on Specific Computational Models G06N 3/02 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 2207/30024 (20130101) G06T 2207/30104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124449 | Shih |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Wei-Chuan Shih (Houston, Texas) |
| ABSTRACT | The present disclosure relates to the fabrication and characterization of an optical fiber capable of firing light virtually from any point along its circumferential surface. The optical fiber is preferably prepared by laser micromachining. In preferred embodiments, laser radiation is focused onto a multimode optical fiber axis, forming a conical-shaped cavity (side window) in the fiber core. Because of the total internal reflection when the laser beam reaches the side window-outside medium interface, the beam is reflected to the side of the optical fiber. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 16/326986 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 25/68 (20130101) C03C 25/1063 (20180101) C03C 25/6208 (20180101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124605 | Cheng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Jianjun Cheng (Champaign, Illinois); Menghua Xiong (Urbana, Illinois); Ziyuan Song (Urbana, Illinois) |
| ABSTRACT | The invention provides antimicrobial polypeptides (AMPs) with high radial amphiphilicity. Unlike typical AMPs characterized by facial amphiphilicity or biomimetic antimicrobial polymers with randomly distributed charged and hydrophobic groups, these new AMPs are homo-polypeptides with radially amphiphilic structure. They adopt a stable α-helical conformation with a hydrophobic helical core and a charged exterior shell, formed by flexible hydrophobic side chains with terminal charge group. The radially amphiphilic polypeptides offer several advantages over conventional AMPs with regard to stability against protease and simplicity of design. They also exhibit high antibacterial activity against both Gram-negative and Gram-positive bacteria and low hemolytic activity. The AMPs thus provide a general platform for treating drug-resistant bacterial infections. |
| FILED | Monday, June 27, 2016 |
| APPL NO | 15/739090 |
| ART UNIT | 1619 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/46 (20130101) A01N 43/40 (20130101) A01N 43/42 (20130101) A01N 43/50 (20130101) A01N 43/52 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/43 (20130101) A61K 31/43 (20130101) A61K 31/65 (20130101) A61K 31/65 (20130101) A61K 31/496 (20130101) A61K 31/496 (20130101) A61K 31/785 (20130101) A61K 31/7036 (20130101) A61K 31/7036 (20130101) A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/10 (20130101) C08G 69/48 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124612 | Scott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Evan A. Scott (Chicago, Illinois); Sean D. Allen (Chicago, Illinois) |
| ABSTRACT | Described herein are flash nanoprecipitation methods capable of encapsulating hydrophobic molecules, hydrophilic molecules, bioactive protein therapeutics, or other target molecules in amphiphilic copolymer nanocarriers. |
| FILED | Friday, April 10, 2020 |
| APPL NO | 16/845831 |
| ART UNIT | 1617 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/107 (20130101) A61K 9/1273 (20130101) A61K 31/352 (20130101) A61K 31/365 (20130101) A61K 31/436 (20130101) A61K 38/465 (20130101) A61K 47/34 (20130101) A61K 47/36 (20130101) A61K 49/0047 (20130101) A61K 49/0054 (20130101) A61K 49/0065 (20130101) Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/0807 (20130101) B01F 3/0861 (20130101) B01F 5/02 (20130101) B01F 5/0256 (20130101) B01F 13/0059 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/14 (20130101) Original (OR) Class C08J 2371/02 (20130101) C08J 2381/02 (20130101) C08J 2381/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2320/32 (20130101) Enzymes C12Y 301/03001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124644 | Angelini et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| INVENTOR(S) | Thomas Ettor Angelini (Gainesville, Florida); Brent S. Sumerlin (Gainesville, Florida); Christopher S. O'Bryan (Gainesville, Florida); Wallace Gregory Sawyer (Gainesville, Florida); Tapomoy Bhattacharjee (Gainesville, Florida) |
| ABSTRACT | An organic microgel system as support material for 3D printing of soft materials such as silicone and methods for manufacturing and using the organic microgel system are disclosed. In some embodiments, the organic microgel system comprises a plurality of microgel particles formed by blending a di-block copolymer and a tri-block copolymer in an organic solvent. The organic microgel system may allow high precision 3D printing of silicone objects with complex shapes. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 15/693389 |
| ART UNIT | 1747 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/40 (20170801) B29C 64/106 (20170801) B29C 64/112 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2009/00 (20130101) B29K 2096/04 (20130101) B29K 2105/0085 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Compositions of Macromolecular Compounds C08L 53/00 (20130101) Original (OR) Class C08L 53/025 (20130101) C08L 53/025 (20130101) C08L 53/025 (20130101) C08L 2205/025 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/10 (20130101) C09D 11/102 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124761 | Lin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Chien-Chi Lin (Indianapolis, Indiana); Camron Scott Dawes (Urbana, Indiana); Heiko Konig (Carmel, Indiana) |
| ABSTRACT | Embodiments of the current invention include a hydrogel formed from crosslinked polyethylene glycol into which acrylated glucose oxidase has been immobilized through crosslinking to the gel. These hydrogels can be used to create hypoxia under ambient conditions for at least 72 hours and can be used to create hypoxic gradients. These embodiments permit the study of cells under a variety of hypoxic conditions. |
| FILED | Thursday, December 06, 2018 |
| APPL NO | 16/212212 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 23/20 (20130101) C12M 25/00 (20130101) C12M 25/14 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0018 (20130101) Original (OR) Class C12N 5/0062 (20130101) C12N 2500/02 (20130101) C12N 2500/34 (20130101) C12N 2500/50 (20130101) C12N 2500/60 (20130101) C12N 2501/70 (20130101) Enzymes C12Y 101/03004 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124772 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kelvin Lee (Newark, Delaware); Xiaolin Zhang (Iselin, New Jersey) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Kelvin Lee (Newark, Delaware); Xiaolin Zhang (Iselin, New Jersey) |
| ABSTRACT | The present invention provides a recombinant eukaryotic cell expressing one or more heterologous double strand break (DSB) repair proteins in an amount effective for enhancing DSB repair in the cell. The recombinant eukaryotic cell may express a recombinant product of interest. Also provided are methods for enhancing double strand break (DSB) repair in eukaryotic cells, establishing host cells for production of a recombinant product of interest, producing a recombinant product of interest, improving production of a recombinant product of interest by eukaryotic cells, and/or investigating suitability of eukaryotic cells as host cells for producing a recombinant product of interest. |
| FILED | Tuesday, April 02, 2019 |
| APPL NO | 16/372932 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0682 (20130101) Original (OR) Class C12N 9/88 (20130101) C12N 9/93 (20130101) C12N 2510/02 (20130101) C12N 2511/00 (20130101) Enzymes C12Y 402/99 (20130101) C12Y 605/01001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124783 | Rajan |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| INVENTOR(S) | Rakhi Rajan (Norman, Oklahoma) |
| ABSTRACT | Bridge helix-modified variant Cas9 proteins having improved DNA cleavage selectivity in comparison to wild type versions of the Cas9 proteins, nucleic acids encoding the variant proteins, host cells containing the nucleic acids, and methods of their use. |
| FILED | Friday, September 13, 2019 |
| APPL NO | 16/570555 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/70 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124814 | Siddiqui et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Michael Shareef Siddiqui (San Mateo, California); Christina D. Smolke (Menlo Park, California) |
| ABSTRACT | Host cells that are engineered to produce benzylisoquinoline alkaloid (BIAs) precursors, such as norcoclaurine (NC) and norlaudanosoline (NL), are provided. The host cells may have one or more engineered modifications selected from: a feedback inhibition alleviating mutation in a enzyme gene; a transcriptional modulation modification of a biosynthetic enzyme gene; an inactivating mutation in an enzyme; and a heterologous coding sequence. Also provided are methods of producing a BIA of interest or a precursor thereof using the host cells and compositions, e.g., kits, systems etc., that find use in methods of the invention. |
| FILED | Monday, November 03, 2014 |
| APPL NO | 15/031618 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0071 (20130101) C12N 9/90 (20130101) C12N 9/1085 (20130101) C12N 15/52 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/24 (20130101) C12P 13/001 (20130101) C12P 13/225 (20130101) C12P 17/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124830 | Lan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regent of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Freeman Lan (San Francisco, California); Benjamin Demaree (Berkeley, California); Iain Clark (San Francisco, California); Adam R. Abate (Daly City, California) |
| ABSTRACT | The present disclosure provides ultrahigh-throughput single cell genomic sequencing methods, referred to herein as “SiC-seq”, which methods include encapsulating single cells in molten gel droplets to facilitate bulk cell lysis and purification of genomic DNA in microgels. Systems and devices for practicing the subject methods are also provided. |
| FILED | Wednesday, April 15, 2020 |
| APPL NO | 16/849344 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) Original (OR) Class C12Q 2565/629 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124846 | Green et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Alexander A. Green (Scottsdale, Arizona); Peng Yin (Brookline, Massachusetts); James J. Collins (Newton, Massachusetts); Jongmin Kim (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides novel and versatile classes of riboregulators, including inter alia activating and repressing riboregulators, switches, and trigger and sink RNA, and methods of their use for detecting RNAs in a sample such as a well and in modulating protein synthesis and expression. |
| FILED | Tuesday, July 14, 2015 |
| APPL NO | 15/326054 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1138 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6897 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125514 | Gan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Buffalo, New York); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Buffalo, New York); Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Qiaoqiang Gan (East Amherst, New York); Haomin Song (Williamsville, New York); Zongfu Yu (Madison, Wisconsin); Ming Zhou (Madison, Wisconsin) |
| ABSTRACT | Disclosed herein are systems and methods for passively cooling water vapor to enable efficient condensation, and methods of making such systems. A passive cooler can include a thermally conductive substrate having a first side and a second side opposite the first side, a coating disposed on at least a portion of the first side of the substrate, and a housing having one or more insulative walls. The insulative walls may define a vapor flow channel from an inlet to an outlet of the housing such that the second side of the substrate is exposed to water vapor flowing through the vapor flow channel. |
| FILED | Thursday, April 04, 2019 |
| APPL NO | 17/045415 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 39/04 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 21/067 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125685 | Markelz et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Buffalo, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Buffalo, New York) |
| INVENTOR(S) | Andrea G. Markelz (Buffalo, New York); Gheorghe Acbas (Milwaukee, Wisconsin); Katherine A. Niessen (Buffalo, New York) |
| ABSTRACT | An apparatus and method for Crystal Anisotropy Terahertz Microscopy (“CATM”) is provided. The apparatus includes an emitter configured to emit a THz pulse and a detector configured to detect the THz pulse after the pulse is transmitted through a sample disposed on a sample surface of the detector. A pulsed radiation generator generates a probe beam to interrogate the detector. The detector may include an electro-optical (“EO”) crystal configured to change in birefringence according to the THz pulse. The sample surface of the detector may have a dielectric coating which is transmissive to THz and reflective to the probe beam. The sample is disposed on the dielectric coating. |
| FILED | Tuesday, January 19, 2016 |
| APPL NO | 15/543752 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/03 (20130101) G01N 21/23 (20130101) G01N 21/3581 (20130101) Original (OR) Class G01N 21/3586 (20130101) G01N 2201/0683 (20130101) G01N 2201/06113 (20130101) Optical Elements, Systems, or Apparatus G02B 21/0004 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125748 | Gopinath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); UNIVERSITY OF BRITISH COLUMBIA (Vancouver, Canada) |
| ASSIGNEE(S) | UNIVERSITY OF BRITISH COLUMBIA (Vancouver, Canada); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Ashwin Gopinath (Cambridge, Massachusetts); Christopher Thachuk (Seattle, Washington); David G. Kirkpatrick (Vancouver, Canada); Paul W. Rothemund (Pasadena, California) |
| ABSTRACT | According to one embodiment of the present invention, a structure includes: a substrate having a patterned surface of one or more binding sites; and a molecular shape made by a polynucleotide platform having a shape corresponding to a shape of a binding site of the one or more binding sites, the molecular shape being bound to one of the one or more binding sites. |
| FILED | Tuesday, September 04, 2018 |
| APPL NO | 16/121603 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 50/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) G01N 21/6445 (20130101) G01N 33/548 (20130101) Original (OR) Class G01N 33/54373 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125772 | Mitchell et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Bliley Technologies, Inc. (Erie, Pennsylvania) |
| ASSIGNEE(S) | BLILEY TECHNOLOGIES, INC. (Erie, Pennsylvania) |
| INVENTOR(S) | Jay Mitchell (Ypsilanti, Michigan); Anthony Challoner (Manhattan Beach, California); Sangwoo Lee (Ann Arbor, Michigan) |
| ABSTRACT | Motion and/or orientation sensing systems can utilize gyroscopes, accelerometers, magnetometers, and other sensors for measuring motion or orientation of connected objects. Temperature changes affect the precision of the data output by the motion/orientation sensing device. A system is provided for controllably heating a device within a package to a desired temperature that varies based on the ambient temperature. The operating temperature of the device can then be known and controlled. The ambient temperature can be known through an ambient temperature sensor, for example. Given this information, a controller compensates the data output by the device to further improve the accuracy in the measurements. Like the amount of heating provided to the package, the amount of compensation is also based on the ambient temperature and/or the device temperature. |
| FILED | Tuesday, July 02, 2019 |
| APPL NO | 16/459775 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/0096 (20130101) B81B 2201/0235 (20130101) B81B 2201/0242 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 25/005 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 13/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 21/00 (20130101) Original (OR) Class G01P 2015/0871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125847 | Eck et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | Case Western Reserve University (Cleveland, Ohio) |
| INVENTOR(S) | Brendan Eck (Cleveland Heights, Ohio); Jesse Hamilton (Cleveland Heights, Ohio); Nicole Seiberlich (Shaker Heights, Ohio); Mark Griswold (Shaker Heights, Ohio) |
| ABSTRACT | A method for magnetic resonance fingerprinting with out-of-view artifact suppression includes acquiring MRF data from a region of interest in a subject. The MRF data is acquired using a non-Cartesian, variable density sampling trajectory. The MRF data includes data from within a desired field-of-view and data from outside the desired field-of-view. The method also includes generating a set of coil images based on the MRF data with a field-of-view larger than the desired field-of-view, determining a noise covariance based on the MRF data from outside the desired field-of-view, generating a coil combined image using an adaptive coil combination determined based on the noise covariance, applying the adaptive coil combination to the MRF data to grid each frame of the MRF data and generate MRF data with out-of-view artifact suppression. The method also includes identifying at least one property of the MRF data and generating a report. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 16/858177 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/50 (20130101) G01R 33/4824 (20130101) G01R 33/4828 (20130101) G01R 33/56545 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11126403 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Jianhua Yang (Hadley, Massachusetts); Qiangfei Xia (Amherst, Massachusetts); Hao Jiang (Sunderland, Massachusetts) |
| ABSTRACT | A true random number generator device based on a diffusive memristor is disclosed. The random number generator device includes a diffusive memristor driven by a pulse generator circuit. The diffusive memristor produces a stochastically switched output signal. A comparator circuit receives the stochastically switched output signal from the diffusive memristor and generates an output signal having a random pulse width. An AND gate logic circuit is driven by a clock signal and the output signal from the comparator circuit. The AND gate logic circuit produces a combined output signal. A counter circuit receives the combined output signal from the AND gate logic circuit and generates a random bit string output signal. |
| FILED | Thursday, March 28, 2019 |
| APPL NO | 16/367623 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 7/588 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/085 (20130101) H01L 45/146 (20130101) H01L 45/1253 (20130101) H01L 45/1266 (20130101) Pulse Technique H03K 3/84 (20130101) H03K 19/20 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0869 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11126905 | Zajic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Alenka Zajic (Atlanta, Georgia); Chia-Lin Cheng (Atlanta, Georgia); Luong N. Nguyen (Atlanta, Georgia); Milos Z. Prvulovic (Atlanta, Georgia) |
| ABSTRACT | A semi-passive radio frequency identification (RFID) tag includes a digital circuit with switching components operating within an interrogation range of an incident carrier wave. A plurality of input connections and output connections direct data communications through the switching components within the digital circuit, and the data communications are subject to switching operations of the switching components between at least one of the input connections and at least one of the output connections. A backscatter response reflected from the digital circuit upon arrival of the incident carrier wave, wherein the backscatter response is a modulated backscatter response in the presence of the switching operations. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 16/685521 |
| ART UNIT | 2688 — Dynamic Storage Systems; Mechanical parts of Disk Drives |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/0008 (20130101) G06K 7/10356 (20130101) G06K 19/0723 (20130101) Original (OR) Class G06K 19/07749 (20130101) Transmission H04B 5/0062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127992 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| ASSIGNEE(S) | Worcester Polytechnic Institute (Worcester, Massachusetts) |
| INVENTOR(S) | Yan Wang (Shrewsbury, Massachusetts); Eric Gratz (Worcester, Massachusetts); Qina Sa (Worcester, Massachusetts); Zhangfeng Zheng (Worcester, Massachusetts); Joseph Heelan (Worcester, Massachusetts) |
| ABSTRACT | Cathode material from exhausted lithium ion batteries are dissolved in a solution for extracting the useful elements Co (cobalt), Ni (nickel), Al (Aluminum) and Mn (manganese) to produce active cathode materials for new batteries. The solution includes compounds of desirable materials such as cobalt, nickel, aluminum and manganese dissolved as compounds from the exhausted cathode material of spent cells. Depending on a desired proportion, or ratio, of the desired materials, raw materials are added to the solution to achieve the desired ratio of the commingled compounds for the recycled cathode material for new cells. The desired materials precipitate out of solution without extensive heating or separation of the desired materials into individual compounds or elements. The resulting active cathode material has the predetermined ratio for use in new cells, and avoids high heat typically required to separate the useful elements because the desired materials remain commingled in solution. |
| FILED | Friday, October 19, 2018 |
| APPL NO | 16/164952 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 15/08 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 7/428 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 3/02 (20130101) C01G 49/02 (20130101) C01G 53/006 (20130101) C01G 53/50 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/02 (20130101) C22B 7/006 (20130101) C22B 7/007 (20130101) C22B 23/043 (20130101) C22B 23/0461 (20130101) C22B 26/12 (20130101) C22B 47/0063 (20130101) C22B 47/0081 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 10/54 (20130101) Original (OR) Class H01M 10/0525 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 10/20 (20151101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/84 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11128682 | Halepovic et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia) |
| ASSIGNEE(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); Old Dominion University Research Foundation (Norfolk, Virginia) |
| INVENTOR(S) | Emir Halepovic (Somerset, New Jersey); Ibrahim Ben Mustafa (Norfolk, Virginia); Tamer Nadeem (Chantilly, Virginia) |
| ABSTRACT | Aspects of the subject disclosure may include, for example, a method comprising sending context information from a mobile wireless device through a control channel to a network server; receiving a policy at the mobile wireless device from the network server, wherein the policy assigns a video streaming bit rate to the mobile wireless device based on the context information; and implementing the policy to control a video streaming session between the mobile wireless device and a media server over a data channel. The context information may include information about the mobile wireless device and/or a user of the mobile wireless device. The policy may be different for each mobile wireless device. Other embodiments are disclosed. |
| FILED | Monday, December 03, 2018 |
| APPL NO | 16/207260 |
| ART UNIT | 2444 — Computer Networks |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/2416 (20130101) H04L 65/4069 (20130101) Original (OR) Class Wireless Communication Networks H04W 88/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11129236 | Sarsilmaz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Selahattin Burak Sarsilmaz (Tampa, Florida); Tansel Yucelen (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Selahattin Burak Sarsilmaz (Tampa, Florida); Tansel Yucelen (Tampa, Florida) |
| ABSTRACT | Disclosed is a multiagent system having multiple agents in communication with each other via a communication network. The agents can be tasked with performing a global objective. At least a subset of the agents can also be tasked with performing a local objective in addition to the global objective. Performance of the local objective can occur without deteriorating performance of the global objective. |
| FILED | Friday, August 02, 2019 |
| APPL NO | 16/530326 |
| ART UNIT | 2416 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 16/9024 (20190101) G06F 17/11 (20130101) Wireless Communication Networks H04W 24/02 (20130101) H04W 84/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11123433 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (Baton Rouge, Louisiana); THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana) |
| ASSIGNEE(S) | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (Baton Rouge, Louisiana); THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana) |
| INVENTOR(S) | Donghui Zhang (Baton Rouge, Louisiana); Vijay John (Destrehan, Louisiana); Yueheng Zhang (New Orleans, Louisiana); Sunting Xuan (Baton Rouge, Louisiana) |
| ABSTRACT | A variety of hydrophobically modified polypeptoids are provided. The hydrophobically modified polypeptoids can include a polyamide backbone having a random copolymer of two or more different types of repeat units, where one or more of the repeat units have nitrogen atom having a hydrophobic substituent attached thereto. Methods of making the hydrophobically modified polypeptoids are also provided, as well as uses of the hydrophobically modified polypeptoids, for example in liposomal drug delivery. |
| FILED | Tuesday, February 07, 2017 |
| APPL NO | 16/306429 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/18 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 47/34 (20130101) Original (OR) Class Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123682 | Moghaddam |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| INVENTOR(S) | Saeed Moghaddam (Gainesville, Florida) |
| ABSTRACT | A liquid desiccant system including a high desorber, a low desorber, and an absorber that are in fluid communication with a working solution, where the high desorber provides rejected water vapor from the working fluid for condensation in a condenser of the low desorber that provides heat for rejection of additional water from the working solution in the low desorber effectively multiplying the heat provided for desorption. The low desorber provided the concentrated working solution to the absorber where water from ambient air is condensed into the concentrated working solution to provide a dilute working solution within a working solution conduit of the absorber that is thermally coupled to an internal cooler of the absorber. In some embodiments, the working solution can be an aqueous solution of at least one ionic liquid. |
| FILED | Wednesday, December 12, 2018 |
| APPL NO | 16/217599 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 53/28 (20130101) B01D 53/263 (20130101) B01D 53/268 (20130101) B01D 53/1425 (20130101) Original (OR) Class B01D 2252/30 (20130101) B01D 2259/65 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/047 (20130101) Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 3/1411 (20130101) F24F 5/0014 (20130101) F24F 2003/1458 (20130101) Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 15/00 (20130101) F25B 15/02 (20130101) F25B 15/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123713 | Berman et al. |
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| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois); UNIVERSITY OF NORTH TEXAS (Denton, Texas); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois); UNIVERSITY OF NORTH TEXAS (Denton, Texas); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Diana Berman (Lemont, Illinois); Elena Shevchenko (Riverside, Illinois); Matteo Cargnello (Stanford, California); Benjamin Diroll (Chicago, Illinois); Emmett Goodman (Stanford, California) |
| ABSTRACT | Provided herein is a method of preparing a porous composite ceramic material and a porous composite ceramic material made by the method of preparing. |
| FILED | Tuesday, June 25, 2019 |
| APPL NO | 16/452451 |
| ART UNIT | 1772 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 23/44 (20130101) B01J 23/75 (20130101) Original (OR) Class B01J 23/462 (20130101) B01J 35/04 (20130101) B01J 35/0013 (20130101) B01J 37/0018 (20130101) B01J 37/024 (20130101) B01J 37/086 (20130101) B01J 37/0203 (20130101) B01J 37/0205 (20130101) B01J 37/345 (20130101) B01J 37/349 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123732 | Kelly et al. |
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| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Ryan T. Kelly (West Richland, Washington); Ying Zhu (Richland, Washington); Richard D. Smith (Richland, Washington) |
| ABSTRACT | Provided herein are methods and systems for biochemical analysis, including compositions and methods for processing and analysis of small cell populations and biological samples (e.g., a robotically controlled chip-based nanodroplet platform). In particular aspects, the methods described herein can reduce total processing volumes from conventional volumes to nanoliter volumes within a single reactor vessel (e.g., within a single droplet reactor) while minimizing losses, such as due to sample evaporation. |
| FILED | Wednesday, February 14, 2018 |
| APPL NO | 15/897022 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/00317 (20130101) B01J 2219/00367 (20130101) B01J 2219/00619 (20130101) B01J 2219/00621 (20130101) B01J 2219/00659 (20130101) B01J 2219/00702 (20130101) B01J 2219/00725 (20130101) B01J 2219/00743 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/00 (20130101) B01L 3/5088 (20130101) B01L 3/50853 (20130101) B01L 3/502753 (20130101) Original (OR) Class B01L 2200/142 (20130101) B01L 2300/0819 (20130101) B01L 2300/0822 (20130101) B01L 2300/0887 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/58 (20130101) C12M 41/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6881 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 60/04 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 1/34 (20130101) G01N 1/2813 (20130101) G01N 30/88 (20130101) G01N 33/68 (20130101) G01N 33/4833 (20130101) G01N 2001/284 (20130101) G01N 2030/8831 (20130101) Optical Elements, Systems, or Apparatus G02B 21/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123921 | Sauers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fermi Research Alliance, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois) |
| INVENTOR(S) | Aaron Sauers (Aurora, Illinois); Robert Kephart (Pioneer, California) |
| ABSTRACT | A method and system for in situ cross-linking of polymers, Bitumen, and other materials to produce arbitrary functional or ornamental three-dimensional features using electron beams provided by mobile accelerators comprises defining a desired pattern for imparting on a target area, mapping the target area, defining at least one discrete voxel in the target area according to the desired pattern to be imparted on the target area, assigning an irradiation value to each of the at least one discrete voxels, and delivering a dose of irradiation to each of the at least one discrete voxels according to the assigned irradiation value. |
| FILED | Friday, November 02, 2018 |
| APPL NO | 16/179546 |
| ART UNIT | 3671 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/135 (20170801) Original (OR) Class B29C 64/264 (20170801) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2105/24 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Construction Of, or Surfaces For, Roads, Sports Grounds, or the Like; Machines or Auxiliary Tools for Construction or Repair E01C 11/005 (20130101) E01C 23/14 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 37/06 (20130101) H01J 37/305 (20130101) H01J 37/1472 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124058 | Stoltz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Eaton Intelligent Power Limited (Dublin, Ireland) |
| ASSIGNEE(S) | Eaton Intelligent Power Limited (Dublin, Ireland) |
| INVENTOR(S) | Thomas Joseph Stoltz (Allen Park, Michigan); Benjamin Daniel Golder (Raleigh, North Carolina); Thomas Alan Genise (Dearborn, Michigan); Glenn Clark Fortune (Farmington Hills, Michigan) |
| ABSTRACT | A system includes a planetary gear assembly having a ring gear, a plurality of planet gears coupled to a carrier, and a sun gear coupled to a main shaft. The system further includes a driven gear coupled to the carrier, a countershaft gear coupled to the driven gear, a motor/generator coupled to the main shaft, and an actuator structured to change a coupling of the ring gear based on a position of the actuator. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 16/784967 |
| ART UNIT | 3659 — Material and Article Handling |
| CURRENT CPC | Arrangement or Mounting of Propulsion Units or of Transmissions in Vehicles; Arrangement or Mounting of Plural Diverse Prime-movers in Vehicles; Auxiliary Drives for Vehicles; Instrumentation or Dashboards for Vehicles; Arrangements in Connection With Cooling, Air Intake, Gas Exhaust or Fuel Supply of Propulsion Units in Vehicles B60K 6/40 (20130101) Original (OR) Class B60K 6/365 (20130101) B60K 6/387 (20130101) B60K 6/442 (20130101) Vehicles, Vehicle Fittings, or Vehicle Parts, Not Otherwise Provided for B60R 16/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124652 | Naskar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Amit K. Naskar (Knoxville, Tennessee); Ngoc Anh Nguyen (Oak Ridge, Tennessee) |
| ABSTRACT | An object comprising: a blend of (i) a phenol-containing polymer and (ii) a nitrile butadiene rubber; wherein the phenol-containing polymer is present in an amount of at least 5 wt % and up to about 95 wt % by total weight of components (i) and (ii). The object may further contain an electrically conducting component dispersed within the blend or on a surface of the blend. Also described is a method of thermal-activated reversible mechanical deformation of the object by (i) deforming the object at a first temperature, which is at or above the glass transition temperature of the object, and applying a stress on the object; (ii) fixing the deformed state by cooling the object to a second temperature of no more than 0° C. while under stress, and removing the stress; and (iii) recovering the object to the original shape by raising the temperature of the object to the first temperature. |
| FILED | Thursday, June 21, 2018 |
| APPL NO | 16/014136 |
| ART UNIT | 1787 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 61/02 (20130101) B29C 61/003 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2055/00 (20130101) B29K 2055/02 (20130101) Compositions of Macromolecular Compounds C08L 9/02 (20130101) C08L 9/02 (20130101) C08L 97/005 (20130101) Original (OR) Class C08L 97/005 (20130101) C08L 2201/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124819 | Roth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Melissa S. Roth (Stanford, California); Krishna K. Niyogi (Lafayette, California); Sean D. Gallaher (Los Angeles, California); Sabeeha Merchant (Los Angeles, California) |
| ABSTRACT | The disclosure is directed to nucleic acid, host cell, and polypeptide compositions encoded by the unicellular green alga Chromochloris zofingiensis, methods of making such compositions, and method of using the compositions to produce astaxanthin. |
| FILED | Thursday, March 15, 2018 |
| APPL NO | 15/922763 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 9/1025 (20130101) C12N 15/52 (20130101) C12N 15/67 (20130101) C12N 15/79 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 23/00 (20130101) Original (OR) Class Enzymes C12Y 203/0102 (20130101) C12Y 203/0104 (20130101) C12Y 203/01158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124865 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Mark Anderson (Madison, Wisconsin); Anthony Schroeder (Madison, Wisconsin); Jacob Mahaffey (Madison, Wisconsin) |
| ABSTRACT | A method to reduce corrosion rates of materials at high temperatures may include heating a mixture and applying the heated mixture to a material to be rendered thermodynamically noble. The mixture may include carbon monoxide and carbon dioxide and the material rendered thermodynamically noble may include copper or other material having similar physical properties. The copper or other similar material may be applied to a structural material and provide a surface interfacing with the mixture of carbon monoxide and carbon dioxide to prevent corrosion of the structural material. In some cases, the structural material may form a heat exchanger defining passageways for a working fluid of a power system and/or may form other passageways of the power system. The copper may be applied to the passageways as a protective coating and then made thermodynamically noble at high temperatures after interactions with the mixture of carbon monoxide and carbon dioxide. |
| FILED | Tuesday, August 28, 2018 |
| APPL NO | 16/114611 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/02 (20130101) C23C 8/16 (20130101) Original (OR) Class Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 9/0037 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 19/06 (20130101) F28F 21/083 (20130101) F28F 21/085 (20130101) F28F 21/087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124885 | Xu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GINER, INC. (Newton, Massachusetts) |
| ASSIGNEE(S) | PLUG POWER INC. (Latham, New York) |
| INVENTOR(S) | Hui Xu (Acton, Massachusetts); Cortney Mittelsteadt (Wayland, Massachusetts); Brian Rasimick (Boston, Massachusetts); Allison Stocks (Somerville, Massachusetts) |
| ABSTRACT | An anode catalyst suitable for use in an electrolyzer. The anode catalyst includes a support and a plurality of catalyst particles disposed on the support. The support may include a plurality of metal oxide or doped metal oxide particles. The catalyst particles, which may be iridium, iridium oxide, ruthenium, ruthenium oxide, platinum, and/or platinum black particles, may be arranged to form one or more aggregations of catalyst particles on the support. Each of the aggregations of catalyst particles may include at least 10 particles, wherein each of the at least 10 particles is in physical contact with at least one other particle. The support particles and their associated catalyst particles may be dispersed in a binder. |
| FILED | Wednesday, June 17, 2015 |
| APPL NO | 14/742422 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/23 (20210101) Original (OR) Class C25B 9/40 (20210101) C25B 9/65 (20210101) C25B 11/067 (20210101) C25B 11/077 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124886 | Kuhl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Opus 12 Incorporated (Berkeley, California); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | Opus 12 Incorporated (Berkeley, California) |
| INVENTOR(S) | Kendra P. Kuhl (Oakland, California); Etosha R. Cave (Berkeley, California); George Leonard (Oakland, California) |
| ABSTRACT | A platform technology that uses a novel membrane electrode assembly including a cathode layer comprising a reduction catalyst and a first anion-and-cation-conducting polymer, an anode layer comprising an oxidation catalyst and a cation-conducting polymer, a membrane layer comprising a cation-conducting polymer, the membrane layer arranged between the cathode layer and the anode layer and conductively connecting the cathode layer and the anode layer, in a COx reduction reactor has been developed. The reactor can be used to synthesize a broad range of carbon-based compounds from carbon dioxide. |
| FILED | Tuesday, April 07, 2020 |
| APPL NO | 16/842659 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/25 (20210101) C25B 9/23 (20210101) Original (OR) Class C25B 11/051 (20210101) C25B 11/057 (20210101) C25B 13/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125657 | Van Berkel |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oakridge, Tennessee) |
| INVENTOR(S) | Gary Van Berkel (Oak Ridge, Tennessee) |
| ABSTRACT | A system for sampling a surface includes a sampling probe including a housing with a probe end having a sampling fluid opening, a sampling fluid supply conduit and a sampling fluid exhaust conduit. The sampling fluid supply conduit supplies sampling fluid to the sampling fluid opening. The sampling fluid exhaust conduit includes a wall, a sampling fluid exhaust conduit inlet opening for removing sampling fluid from the sampling fluid opening, and a sampling fluid exhaust conduit outlet opening for removing fluid from the sampling fluid exhaust conduit. A sampling fluid analytic conduit is also provided in the sampling probe and has a sampling fluid analytic conduit inlet opening spaced upstream from the sampling fluid exhaust conduit outlet opening, downstream from the sampling fluid exhaust conduit inlet opening, and from the wall of the sampling fluid exhaust conduit. A wash conduit can also be provided. Methods for sampling are also disclosed. |
| FILED | Tuesday, January 30, 2018 |
| APPL NO | 15/883560 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/20 (20130101) Original (OR) Class G01N 1/24 (20130101) G01N 2001/028 (20130101) G01N 2001/2285 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/0431 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125700 | Shaner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Eric A. Shaner (Rio Rancho, New Mexico); Michael Goldflam (Albuquerque, New Mexico); Clark N. Kadlec (Albuquerque, New Mexico) |
| ABSTRACT | A time-resolved microwave reflectance apparatus comprises a pulsed or modulated optical source that irradiates a semiconductor sample with an excitation pump beam, a microwave oscillator that irradiates the sample with a continuous beam of microwaves, and a microwave detector that detects the microwaves reflected by the sample. Therefore, charge detection, rather than conventional absorption measurements (that detect the loss of photons), can be used to extract the absorption coefficient and band edge of a semiconductor material. |
| FILED | Monday, August 19, 2019 |
| APPL NO | 16/543891 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 22/02 (20130101) Original (OR) Class Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/091 (20130101) Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125739 | Sharei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Armon R. Sharei (Watertown, Massachusetts); Marc Lajoie (Seattle, Washington); Klavs F. Jensen (Lexington, Massachusetts); Robert S. Langer (Newton, Massachusetts) |
| ABSTRACT | Gene editing can be performed by introducing gene-editing components into a cell by mechanical cell disruption. Related apparatus, systems, techniques, and articles are also described. The methods and systems of the invention solve the problem of intracellular delivery of gene editing components and gene editing complexes to target cells. The results described herein indicate that delivery of gene editing components, e.g., protein, ribonucleic acid (RNA), and deoxyribonucleic acid (DNA), by mechanical disruption of cell membranes leads to successful gene editing. Because intracellular delivery of gene editing materials is a current challenge, the methods provide a robust mechanism to engineer target cells without the use of potentially harmful viral vectors or electric fields. |
| FILED | Tuesday, January 12, 2016 |
| APPL NO | 15/542892 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5002 (20130101) Original (OR) Class G01N 33/48721 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11126789 — Method to convert a written procedure to structured data, and related systems and methods
| US 11126789 | Oxstrand et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Johanna H. Oxstrand (Idaho Falls, Idaho); Katya L. Le Blanc (Idaho Falls, Idaho); Ahmad Y. Al Rashdan (Ammon, Idaho); Aaron Bly (Idaho Falls, Idaho) |
| ABSTRACT | Various embodiments described in this disclosure relate to methods and computer-based systems that implement those methods for converting tasks performed as part of a procedure into dynamic procedure tasks. Such dynamic procedure tasks may be used by computer-based procedure solutions to create highly dynamic computer-based procedures. |
| FILED | Monday, December 17, 2018 |
| APPL NO | 16/222730 |
| ART UNIT | 2657 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 16/22 (20190101) G06F 40/131 (20200101) G06F 40/143 (20200101) Original (OR) Class G06F 40/151 (20200101) G06F 40/211 (20200101) G06F 40/242 (20200101) G06F 40/279 (20200101) G06F 40/284 (20200101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/10 (20130101) G06Q 10/103 (20130101) G06Q 10/0631 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11126895 | Anirudh et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Rushil Anirudh (Dublin, California); Peer-Timo Bremer (Livermore, California); Jayaraman Jayaraman Thiagarajan (Milpitas, California); Bhavya Kailkhura (Dublin, California) |
| ABSTRACT | Methods and systems are provided to generate an uncorrupted version of an image given an observed image that is a corrupted version of the image. In some embodiments, a corruption mimicking (“CM”) system iteratively trains a corruption mimicking network (“CMN”) to generate corrupted images given modeled images, updates latent vectors based on differences between the corrupted images and observed images, and applies a generator to the latent vectors to generate modeled images. The training, updating, and applying are performed until modeled images that are input to the CMN result in corrupted images that approximate the observed images. Because the CMN is trained to mimic the corruption of the observed images, the final modeled images represented the uncorrupted version of the observed images. |
| FILED | Saturday, April 04, 2020 |
| APPL NO | 16/840358 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6202 (20130101) G06K 9/6256 (20130101) G06K 9/6267 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127127 | Yang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Yongchao Yang (Lemont, Illinois) |
| ABSTRACT | A method of determining dynamic properties of a structure (linear or nonlinear) includes receiving spatio-temporal inputs, generating mode shapes and modal components corresponding to the spatio-temporal inputs using a trained deep complexity coding artificial neural network, and subsequently generating the dynamic properties by analyzing each modal component using a trained learning machine. A computing system for non-contact determination of dynamic properties of a structure includes a camera, a processor, and a memory including computer-executable instructions. When the instructions are executed, the system is caused to receive spatio-temporal image data, decompose the spatio-temporal image data into constituent manifold components using an autoencoder, and analyze the constituent manifold components using a trained learning machine to determine the dynamic properties. |
| FILED | Monday, June 03, 2019 |
| APPL NO | 16/429857 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0445 (20130101) Image Data Processing or Generation, in General G06T 7/0002 (20130101) Original (OR) Class G06T 2207/10016 (20130101) G06T 2207/10024 (20130101) G06T 2207/10028 (20130101) G06T 2207/10036 (20130101) G06T 2207/10048 (20130101) G06T 2207/10056 (20130101) G06T 2207/10061 (20130101) G06T 2207/10068 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30184 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127979 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Zhengcheng Zhang (Naperville, Illinois); Adam P. Tornheim (Darien, Illinois); Meinan He (Willowbrook, Illinois); Jason Croy (Plainfield, Illinois) |
| ABSTRACT | A non-aqueous solvent composition for a lithium battery comprises a fluorinated solvent mixture that consists essentially of a 1,2-difluoroethylene carbonate and a fluoro-substituted dialkyl carbonate in a respective weight ratio of about 1:3 to about 1:1, and optionally up to about 30 wt % of an additional organic solvent. An electrolyte for a lithium ion battery comprises a lithium salt dissolved in a non-aqueous solvent composition comprising the fluorinated solvent mixture. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 15/923687 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/131 (20130101) H01M 4/133 (20130101) H01M 10/0525 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 2004/027 (20130101) H01M 2004/028 (20130101) H01M 2300/0034 (20130101) H01M 2300/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127980 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Ji-Guang Zhang (Richland, Washington); Haiping Jia (Richland, Washington); Xiaolin Li (Richland, Washington); Wu Xu (Richland, Washington) |
| ABSTRACT | Localized superconcentrated electrolytes (LSEs) for use in systems with silicon-based or carbon/silicon composite-based anodes are disclosed. The LSEs include an active salt, a nonaqueous solvent in which the active salt is soluble, and a diluent in which the active salt has a solubility at least 10 times less than solubility of the active salt in the nonaqueous solvent. Systems including the LSEs also are disclosed. |
| FILED | Monday, January 14, 2019 |
| APPL NO | 16/247143 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/133 (20130101) H01M 4/134 (20130101) H01M 4/364 (20130101) H01M 4/366 (20130101) H01M 4/386 (20130101) H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/587 (20130101) H01M 4/621 (20130101) H01M 4/622 (20130101) H01M 10/0525 (20130101) H01M 10/0567 (20130101) H01M 10/0568 (20130101) H01M 10/0569 (20130101) Original (OR) Class H01M 10/4235 (20130101) H01M 2300/004 (20130101) H01M 2300/0037 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11128062 | Schmit |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Deere and Company (Moline, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher J. Schmit (Fargo, North Dakota) |
| ABSTRACT | A folded outer tab comprises a first outer dielectric layer and a second outer dielectric layer that contact or overlie an outer terminal, where the outer terminal is associated with a first polarity of the DC bus. A bent inner tab comprises a first inner dielectric layer and a second inner dielectric layer that contact or overlie an inner terminal, where the inner terminal is associated with a second polarity of the DC bus that is opposite the first polarity. The folded outer tab and the bent inner tab comprise electrically conductive faces, of opposite polarities, formed of exposed portions of the outer terminal and the inner terminal. |
| FILED | Thursday, December 05, 2019 |
| APPL NO | 16/704627 |
| ART UNIT | 2833 — Electrical Circuits and Systems |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 4/46 (20130101) Original (OR) Class Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11128209 | Bird |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Portland State University (Portland, Oregon) |
| ASSIGNEE(S) | Portland State University (Portland, Oregon) |
| INVENTOR(S) | Jonathan Bird (Portland, Oregon) |
| ABSTRACT | This application relates to translating mechanical energy from a low-speed rotor to a high-speed rotor or vice versa in a magnetic gearbox. More specifically, this application discloses various embodiments of a coaxial magnetic gearbox with flux concentration Halbach rotors. In certain implementations, the device further comprises a circular back iron (or other ferromagnetic material) disposed concentrically along the axis of the cylindrical magnetic gearing device. In such embodiments, this flux concentration back iron (or ferromagnetic pole) improves the torque density and can also help retain the magnets in place. |
| FILED | Friday, March 16, 2018 |
| APPL NO | 16/494634 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 49/102 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11128248 | Sozer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yilmaz Sozer (Stow, Ohio) |
| ASSIGNEE(S) | The Universitv of Akron (Akron, Ohio) |
| INVENTOR(S) | Yilmaz Sozer (Stow, Ohio) |
| ABSTRACT | A control system for a switched reluctance machine includes a capacitor and an inverter connected to the capacitor, wherein the inverter generates current signals and a ripple current returned to the capacitor. A switched reluctance machine (SRM) receives the current signals and generates a position signal. A controller receives the ripple current, current signal values of the current signals, and the position signal and generates desired reference current waveforms received by the inverter to adjust the current signals received by the SRM. |
| FILED | Thursday, February 21, 2019 |
| APPL NO | 16/969012 |
| ART UNIT | 2846 — Electrical Circuits and Systems |
| CURRENT CPC | Control or Regulation of Electric Motors, Electric Generators or Dynamo-electric Converters; Controlling Transformers, Reactors or Choke Coils H02P 25/098 (20160201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11123797 | Hofmann |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Douglas C. Hofmann (Altadena, California) |
| ABSTRACT | Methods and alloy systems for non-Be BMG matrix composite materials that can be used to additively manufacturing parts with superior mechanical properties, especially high toughness and strength, are provided. Alloys are directed to BMGMC materials comprising a high strength BMG matrix reinforced with properly scaled, soft, crystalline metal dendrite inclusions dispersed throughout the matrix in a sufficient concentration to resist fracture. |
| FILED | Monday, June 04, 2018 |
| APPL NO | 15/996913 |
| ART UNIT | 1733 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 10/10 (20210101) Original (OR) Class B22F 10/20 (20210101) B22F 2301/205 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/0093 (20130101) B23K 26/342 (20151001) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Alloys C22C 1/0458 (20130101) C22C 16/00 (20130101) C22C 33/0278 (20130101) C22C 38/002 (20130101) C22C 38/02 (20130101) C22C 38/12 (20130101) C22C 2200/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124290 | Raghu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Fluidics LLC (Columbia, Maryland) |
| ASSIGNEE(S) | Advanced Fluidics LLC (Columbia, Maryland) |
| INVENTOR(S) | Surya Raghu (Ellicott City, Maryland) |
| ABSTRACT | An aerodynamic flow control system includes a plurality of actuator units integrated at predetermined locations along a span of an aerodynamic surface of a vehicle to provide aerodynamic active air flow control, wherein each of the plurality of actuator units includes an electrically powered compressor to compress air; a transitional component to receive the compressed air from the compressor and provide two streams of the compressed air; and a fluidic oscillator having two inlet ports that receive the two streams of the compressed air, and an exit port that discharges a single oscillating flow of air at a predetermined velocity. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 15/962963 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 21/04 (20130101) Original (OR) Class B64C 2230/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124413 | Coogan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Southwest Research Institute (San Antonio, Texas) |
| ASSIGNEE(S) | SOUTHWEST RESEARCH INSTITUTE (San Antonio, Texas) |
| INVENTOR(S) | Shane Bucy Coogan (Allen, Texas); Michael A. Miller (San Antonio, Texas) |
| ABSTRACT | The present invention relates generally in gaseous oxygen propulsion systems with solid-phase chemical oxygen generation for in-space propulsion systems. Chemical oxygen generation is provided by alkali metal chlorates, alkali metal perchlorates or metal peroxides. |
| FILED | Friday, January 12, 2018 |
| APPL NO | 15/870395 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 13/0203 (20130101) C01B 13/0211 (20130101) C01B 13/0218 (20130101) Original (OR) Class Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 29/02 (20130101) Means for Generating Smoke or Mist; Gas-attack Compositions; Generation of Gas for Blasting or Propulsion C06D 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124464 | Sherman et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Terves Inc. (Euclid, Ohio) |
| ASSIGNEE(S) | Terves, LLC (Euclid, Ohio) |
| INVENTOR(S) | Andrew J. Sherman (Mentor, Ohio); Brian Werry (Euclid, Ohio); Andrew Cortopassi (Euclid, Ohio); Eric Boyer (Euclid, Ohio) |
| ABSTRACT | A high density, generally recognized as safe hybrid rocket motor is described which has a density-specific impulse similar to a solid rocket motor, with good performance approaching or equal to a liquid rocket motor. These high density hybrid motors resolve the packaging efficiency/effectiveness problems limiting the application of safe, low cost hybrid motor technology. |
| FILED | Wednesday, August 30, 2017 |
| APPL NO | 15/690515 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 23/001 (20130101) C06B 23/006 (20130101) C06B 31/28 (20130101) Original (OR) Class Detonating or Priming Devices; Fuses; Chemical Lighters; Pyrophoric Compositions C06C 9/00 (20130101) Means for Generating Smoke or Mist; Gas-attack Compositions; Generation of Gas for Blasting or Propulsion C06D 5/10 (20130101) Jet-propulsion Plants F02K 9/24 (20130101) F02K 9/26 (20130101) F02K 9/70 (20130101) F02K 9/72 (20130101) F02K 9/425 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124608 | Scott et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); MATERIAL ANSWERS LLC (Weston, Massachusetts) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio); MATERIAL ANSWERS LLC (Weston, Massachusetts) |
| INVENTOR(S) | Christopher E. Scott (Weston, Massachusetts); Hatsuo Ishida (Shaker Heights, Ohio); Scott Allen Winroth (Ayer, Massachusetts) |
| ABSTRACT | A material with significant protection properties from galactic cosmic radiation and solar energetic particles. Hydrogen-rich benzoxazines which are particularly effective for shielding against such radiation. Benzoxazine resin meets the processing requirements for use with ultra-high molecular weight polyethylene fiber as a hydrogen-rich reinforcement: cure of the resin at 120° C. This highly reactive benzoxazine resin also exhibits low viscosity and adequate shelf life. |
| FILED | Thursday, April 04, 2019 |
| APPL NO | 16/375415 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/0273 (20130101) Original (OR) Class Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 5/24 (20130101) C08J 2379/02 (20130101) C08J 2423/06 (20130101) Compositions of Macromolecular Compounds C08L 23/06 (20130101) C08L 79/02 (20130101) C08L 2205/16 (20130101) C08L 2207/062 (20130101) C08L 2207/068 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 9/009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125915 | Mecikalski |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | John R. Mecikalski (Madison, Alabama) |
| ASSIGNEE(S) | Board of Trustees of the University of Alabama, for and on behalf of the University of Alabama in Huntsville (Huntsville, Alabama) |
| INVENTOR(S) | John R. Mecikalski (Madison, Alabama) |
| ABSTRACT | A weather forecasting system has memory for storing satellite image data and numerical weather prediction (NWP) model data, which indicates predicted atmospheric conditions for a geographic region. At least one processor is programmed to identify a cumulus cloud within the satellite image data and to define a zone of influence around the cumulus cloud. The zone of influence represents a boundary for the NWP model data to be used by the processor for predicting whether the cumulus cloud will produce a weather event (e.g., precipitation, convective storm, etc.) in the future. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 16/818723 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Meteorology G01W 1/10 (20130101) Original (OR) Class Electric Digital Data Processing G06F 17/10 (20130101) G06F 30/20 (20200101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 2207/30192 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127508 | Lake et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BWXT Nuclear Energy, Inc. (Lynchburg, Virginia) |
| ASSIGNEE(S) | BWXT Nuclear Energy, Inc. (Lynchburg, Virginia) |
| INVENTOR(S) | Russell L. Lake (Evington, Virginia); James B. Inman (Forest, Virginia); Roger D. Ridgeway (Rustburg, Virginia) |
| ABSTRACT | A packing device for filling fuel elements with a powder through a fill aperture in an outer shell of the fuel element, including a stationary base, a clamp assembly including a body defining a bore therein, the bore being configured to slidably receive a fuel element therein, wherein the clamp assembly is movable along a vertical axis with respect to the stationary base, a cam assembly including a cam and a drive motor configured to rotate the cam, wherein rotation of the cam alternatingly raises the clamp assembly up along the vertical axis and subsequently drops the clamping assembly, and a powder reservoir assembly including a powder reservoir and a fill needle in fluid communication with the powder reservoir. |
| FILED | Monday, October 07, 2019 |
| APPL NO | 16/594530 |
| ART UNIT | 3753 — Fluid Handling and Dispensing |
| CURRENT CPC | Nuclear Reactors G21C 21/00 (20130101) G21C 21/02 (20130101) G21C 21/04 (20130101) Original (OR) Class Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 30/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127537 | Brambilla et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FastCAP SYSTEMS Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | FASTCAP SYSTEMS CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Nicolò Michele Brambilla (Boston, Massachusetts); Fabrizio Martini (Boston, Massachusetts) |
| ABSTRACT | Electric double layer capacitor devices are disclosed. The devices may be suitable for operation of wide temperature ranges. In some cases, the capacitor features a solid state electrolyte that includes an ionic liquid doped polymer matrix. |
| FILED | Wednesday, July 26, 2017 |
| APPL NO | 15/660950 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/15 (20130101) H01G 9/028 (20130101) H01G 11/04 (20130101) Original (OR) Class H01G 11/56 (20130101) H01G 11/62 (20130101) H01G 11/64 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11128293 | Krasowski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as Represented by the Administrator of National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Michael J. Krasowski (Cleveland, Ohio); Norman F. Prokop (Cleveland, Ohio); Philip G. Neudeck (Cleveland, Ohio); David J. Spry (Cleveland, Ohio) |
| ABSTRACT | Methods and devices are disclosed for compensating for device property variations across a wafer. The method comprises determining an output of a first device based on an input and determining an output of a second device based on the input. The second device is located at a different position with respect to a center of the wafer than a position of the first device with respect to the center of the wafer. The method further comprises determining a difference between the output of the first device and the output of the second device, the difference arising at least in part from the difference in position of the first and second devices. The method further comprises altering the first device such that the output of the first device based on the input substantially matches the output of the second device based on the input. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/939612 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/808 (20130101) H01L 29/1608 (20130101) Pulse Technique H03K 17/12 (20130101) H03K 17/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11122751 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
| ASSIGNEE(S) | WASHINGTON STATE UNIVERSITY (Pullman, Washington) |
| INVENTOR(S) | Xiao Zhang (Richland, Washington); Changki Mo (Richland, Washington); Matthew David Whiting (Prosser, Washington); Qin Zhang (Richland, Washington) |
| ABSTRACT | Compositions and methods of protecting plants from cold damage are provided. In particular, the invention provides compositions comprising plant-based nano- and/or micron-sized particles which, when applied to plants or plant parts such as buds, form a non-hydrophilic deposit or film with low thermal conductivity, thereby conferring protection against damage from ice nucleation and cold stress. |
| FILED | Tuesday, October 06, 2020 |
| APPL NO | 17/064139 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 13/065 (20130101) Original (OR) Class Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 105/14 (20130101) C09D 197/02 (20130101) C09D 197/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11123415 | Gourapura et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| INVENTOR(S) | Renukaradhya Gourapura (Wooster, Ohio); Ramesh Selvaraj (Wooster, Ohio); Sankar Renu (Wooster, Ohio) |
| ABSTRACT | The present disclosure relates to nanoparticle compositions for use as vaccines against Salmonella. |
| FILED | Thursday, August 16, 2018 |
| APPL NO | 16/639311 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/5161 (20130101) A61K 39/116 (20130101) A61K 39/0275 (20130101) Original (OR) Class A61K 2039/542 (20130101) A61K 2039/55555 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11124819 | Roth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Melissa S. Roth (Stanford, California); Krishna K. Niyogi (Lafayette, California); Sean D. Gallaher (Los Angeles, California); Sabeeha Merchant (Los Angeles, California) |
| ABSTRACT | The disclosure is directed to nucleic acid, host cell, and polypeptide compositions encoded by the unicellular green alga Chromochloris zofingiensis, methods of making such compositions, and method of using the compositions to produce astaxanthin. |
| FILED | Thursday, March 15, 2018 |
| APPL NO | 15/922763 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 9/1025 (20130101) C12N 15/52 (20130101) C12N 15/67 (20130101) C12N 15/79 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 23/00 (20130101) Original (OR) Class Enzymes C12Y 203/0102 (20130101) C12Y 203/0104 (20130101) C12Y 203/01158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125227 | Vacca et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Andrea Vacca (Lafayette, Indiana); Sujan Dhar (Seattle, Washington); Divya Thiagarajan (Lafayette, Indiana) |
| ABSTRACT | Devices and systems relating to external gear machines that comprise microsurface shaping on the lateral surfaces of the gear teeth and/or bushing surfaces are provided. Such microsurface shaping may comprise a flat step to linear wedge profile, a flat step to flat step profile, or solely a linear wedge profile. The incorporation of microsurface shaping on the gear teeth and/or bushing plates contributes to improving the lubrication performance within the external gear machine and provides significant benefits, including the improvement of operating efficiency, life, and reliability of the system components. Methods for manufacturing the gear teeth and related bushings are also provided, the methods configured to optimize the overall axial balance within the system. |
| FILED | Tuesday, February 21, 2017 |
| APPL NO | 15/999459 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Rotary-piston or Oscillating-piston Machines or Engines F01C 21/02 (20130101) Rotary-piston, or Oscillating-piston, Positive-displacement Machines for Liquids; Rotary-piston, or Oscillating-piston, Positive-displacement Pumps F04C 2/082 (20130101) Original (OR) Class F04C 2/084 (20130101) F04C 2240/56 (20130101) Shafts; Flexible Shafts; Elements or Crankshaft Mechanisms; Rotary Bodies Other Than Gearing Elements; Bearings F16C 33/106 (20130101) F16C 33/1025 (20130101) Gearing F16H 1/06 (20130101) F16H 55/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125743 | Green et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| INVENTOR(S) | Alexander Green (Scottsdale, Arizona); Duo Ma (Tempe, Arizona); Luhui Shen (Tempe, Arizona); Chris Diehnelt (Chandler, Arizona) |
| ABSTRACT | Provided herein are methods and systems for low-cost, low-equipment detection of pathogens in biological sample. In particular, provided herein is a low-cost method for detecting norovirus that provides reliable, visible test with femtomolar, attomolar, and zeptomolar detection limits and that uses materials suitable for deployment of the methods in the field. |
| FILED | Tuesday, February 19, 2019 |
| APPL NO | 16/279045 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 19/00 (20130101) C07K 2317/60 (20130101) C07K 2317/569 (20130101) C07K 2318/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/569 (20130101) G01N 33/5308 (20130101) G01N 33/5434 (20130101) G01N 33/54306 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11124885 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GINER, INC. (Newton, Massachusetts) |
| ASSIGNEE(S) | PLUG POWER INC. (Latham, New York) |
| INVENTOR(S) | Hui Xu (Acton, Massachusetts); Cortney Mittelsteadt (Wayland, Massachusetts); Brian Rasimick (Boston, Massachusetts); Allison Stocks (Somerville, Massachusetts) |
| ABSTRACT | An anode catalyst suitable for use in an electrolyzer. The anode catalyst includes a support and a plurality of catalyst particles disposed on the support. The support may include a plurality of metal oxide or doped metal oxide particles. The catalyst particles, which may be iridium, iridium oxide, ruthenium, ruthenium oxide, platinum, and/or platinum black particles, may be arranged to form one or more aggregations of catalyst particles on the support. Each of the aggregations of catalyst particles may include at least 10 particles, wherein each of the at least 10 particles is in physical contact with at least one other particle. The support particles and their associated catalyst particles may be dispersed in a binder. |
| FILED | Wednesday, June 17, 2015 |
| APPL NO | 14/742422 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/23 (20210101) Original (OR) Class C25B 9/40 (20210101) C25B 9/65 (20210101) C25B 11/067 (20210101) C25B 11/077 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11125772 | Mitchell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Bliley Technologies, Inc. (Erie, Pennsylvania) |
| ASSIGNEE(S) | BLILEY TECHNOLOGIES, INC. (Erie, Pennsylvania) |
| INVENTOR(S) | Jay Mitchell (Ypsilanti, Michigan); Anthony Challoner (Manhattan Beach, California); Sangwoo Lee (Ann Arbor, Michigan) |
| ABSTRACT | Motion and/or orientation sensing systems can utilize gyroscopes, accelerometers, magnetometers, and other sensors for measuring motion or orientation of connected objects. Temperature changes affect the precision of the data output by the motion/orientation sensing device. A system is provided for controllably heating a device within a package to a desired temperature that varies based on the ambient temperature. The operating temperature of the device can then be known and controlled. The ambient temperature can be known through an ambient temperature sensor, for example. Given this information, a controller compensates the data output by the device to further improve the accuracy in the measurements. Like the amount of heating provided to the package, the amount of compensation is also based on the ambient temperature and/or the device temperature. |
| FILED | Tuesday, July 02, 2019 |
| APPL NO | 16/459775 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 7/0096 (20130101) B81B 2201/0235 (20130101) B81B 2201/0242 (20130101) Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 25/005 (20130101) Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 13/00 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 21/00 (20130101) Original (OR) Class G01P 2015/0871 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11128082 | Wise et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Blink Astro, LLC (Atlanta, Georgia) |
| ASSIGNEE(S) | Blink Astro, LLC (Atlanta, Georgia) |
| INVENTOR(S) | Evan Shelby Wise (Atlanta, Georgia); John Terrell Madigan (Atlanta, Georgia); William Carlton Doncaster (Atlanta, Georgia); Kevin Marcus Feld (Atlanta, Georgia); Jon Grant Wallace (Atlanta, Georgia); Matthew David Arceri (Atlanta, Georgia); Wahaj Umar Khan (Atlanta, Georgia) |
| ABSTRACT | Androgynous modular connectors (e.g., modular spacecraft connectors) are disclosed herein. The modular connectors can include prismatic-shaped body with side panels, a base, and a face panel. The face panel can include three or more sides that define an opening. A claw assembly can be housed within the prismatic-shaped body. The claw assembly can include two or more extendable arms. A motor can be housed within the prismatic-shaped body. The motor can be operatively connected to the claw assembly. The motor can be configured to extend and retract the claw assembly. |
| FILED | Friday, September 27, 2019 |
| APPL NO | 16/586232 |
| ART UNIT | 2831 — Electrical Circuits and Systems |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/64 (20130101) Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 12/70 (20130101) H01R 13/514 (20130101) Original (OR) Class H01R 13/6273 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11126551 | Dargan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | John L. Dargan (Ashburn, Virginia); Damian Garcia (Fort Washington, Maryland); Archie Turner (Williamsburg, Virginia); Carlos M. Lizardi (New Windsor, Maryland); Lorraine Castillo (Navarre, Florida) |
| ABSTRACT | Systems and methods are described, and an example system includes logic that implements a user interface and that accepts an indicator of data, and upon identifying the data is restricted access, receives via the interface attributes of tasks, and of the user, and determines a task-user attribute matrix based on the user input. The logic sends a data-coefficient request to access modules, receives a reply message that includes sensitivity metadata coefficient, a privacy metadata coefficient, a combinability metadata coefficient, and a security metadata coefficient. The logic constructs, using a content of the reply message, a metadata coefficient matrix. The logic applies a dynamic access evaluation that is based on the task-user attribute matrix and the metadata coefficient matrix and, upon a positive evaluation, accesses the restricted-access data and provides the accessed data to a data cache. Optionally, the data cache feeds a system of system operational analytics. |
| FILED | Tuesday, October 27, 2020 |
| APPL NO | 17/081638 |
| ART UNIT | 2133 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 3/0622 (20130101) G06F 3/0655 (20130101) G06F 3/0679 (20130101) G06F 12/0802 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0639 (20130101) G06Q 50/265 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127013 | Boyd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Daniel Boyd (Arlington, Virginia); Arun Vemury (North Bethesda, Maryland) |
| ABSTRACT | An improvement to the function of computer systems, including those that verify the identity of subjects arriving at checkpoints, is realized by (a) relying on a central resource, instead of checkpoints, to perform biometric comparisons, (b) using lists of expected subjects at the checkpoints, (c) providing rolling updates to the list of expected subjects as warranted by changes, and (d) locking the records of subjects once their identity is verified. The improvement resides in specialized logic that is specifically tailored to the checkpoint environment and, as such, leads to reduced computing resource consumption for the processing system, the memory, the network, and the components that interface with the network. |
| FILED | Monday, October 07, 2019 |
| APPL NO | 16/595095 |
| ART UNIT | 3696 — Business Methods - Finance/Banking/ Insurance |
| CURRENT CPC | Electric Digital Data Processing G06F 16/22 (20190101) G06F 21/32 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/06037 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/40145 (20130101) Original (OR) Class G06Q 50/265 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11124892 | Bondokov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robert T. Bondokov (Watervliet, New York); Kenneth E. Morgan (Castleton, New York); Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York) |
| ASSIGNEE(S) | CRYSTAL IS, INC. (Green Island, New York) |
| INVENTOR(S) | Robert T. Bondokov (Watervliet, New York); Kenneth E. Morgan (Castleton, New York); Leo J. Schowalter (Latham, New York); Glen A. Slack (Scotia, New York) |
| ABSTRACT | Bulk single crystal of aluminum nitride (AlN) having an areal planar defect density ≤100 cm−2. Methods for growing single crystal aluminum nitride include melting an aluminum foil to uniformly wet a foundation with a layer of aluminum, the foundation forming a portion of an AlN seed holder, for an AlN seed to be used for the AlN growth. The holder may consist essentially of a substantially impervious backing plate. |
| FILED | Friday, May 22, 2020 |
| APPL NO | 16/881148 |
| ART UNIT | 1714 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 23/00 (20130101) C30B 23/025 (20130101) Original (OR) Class C30B 29/403 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/02389 (20130101) Technical Subjects Covered by Former US Classification Y10T 428/2982 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11127309 | Kirkman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Robin Kirkman (Centreville, Virginia) |
| ASSIGNEE(S) | The MITRE Corporation (McLean, Virginia) |
| INVENTOR(S) | Robin Kirkman (Centreville, Virginia) |
| ABSTRACT | A method of performing a flight simulation is provided. The method includes retrieving a flight action; mapping the flight action to an instruction, the instruction being configured to bring about a desired state of a flight simulator; identifying a command based on the desired state of the flight simulator and a first state of the flight simulator; and determining if a second state of the flight simulator after executing the command matches the desired state of the flight simulator. |
| FILED | Tuesday, August 09, 2011 |
| APPL NO | 13/205990 |
| ART UNIT | 2128 — AI & Simulation/Modeling |
| CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 9/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11124490 | Miller et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Memphis, Tennessee); UNIVERSITY OF MEMPHIS (Memphis, Tennessee) |
| ASSIGNEE(S) | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (Memphis, Tennessee); UNIVERSITY OF MEMPHIS (Memphis, Tennessee) |
| INVENTOR(S) | Duane D. Miller (Memphis, Tennessee); Gabor G. Tigyi (Memphis, Tennessee); Souvik Banerjee (Memphis, Tennessee); Abby L. Parrill-Baker (Memphis, Tennessee) |
| ABSTRACT | The present disclosure provides novel ATX inhibitors, and pharmaceutical compositions comprising said inhibitors, as well as methods of treatment comprising administration of said inhibitors. |
| FILED | Friday, June 02, 2017 |
| APPL NO | 16/305345 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 241/04 (20130101) C07D 265/30 (20130101) Original (OR) Class C07D 295/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 11124449 | Shih |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | University of Houston System (Houston, Texas) |
| INVENTOR(S) | Wei-Chuan Shih (Houston, Texas) |
| ABSTRACT | The present disclosure relates to the fabrication and characterization of an optical fiber capable of firing light virtually from any point along its circumferential surface. The optical fiber is preferably prepared by laser micromachining. In preferred embodiments, laser radiation is focused onto a multimode optical fiber axis, forming a conical-shaped cavity (side window) in the fiber core. Because of the total internal reflection when the laser beam reaches the side window-outside medium interface, the beam is reflected to the side of the optical fiber. |
| FILED | Thursday, August 31, 2017 |
| APPL NO | 16/326986 |
| ART UNIT | 1741 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 25/68 (20130101) C03C 25/1063 (20180101) C03C 25/6208 (20180101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11128750 | Lack |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Invincea, Inc. (Reston, Virginia) |
| ASSIGNEE(S) | Invincea, Inc. (Reston, Virginia) |
| INVENTOR(S) | Michael Nathan Lack (Arlington, Virginia) |
| ABSTRACT | An apparatus includes a memory of a mobile compute device, and a hardware processor of the mobile compute device. The hardware processor is configured to implement an operating system and an authentication module. The operating system is configured to receive a first authentication identifier, and is also configured to authorize use of the mobile compute device based on the first authentication identifier meeting a first criterion. The authentication module is configured to, in response to the operating system authorizing use of the mobile compute device, disable at least one function of the mobile compute device and request a second authentication identifier. The authentication module is also configured to receive the second authentication identifier. The authentication module is also configured to enable the at least one function in response to the second authentication identifier meeting a second criterion. |
| FILED | Monday, July 13, 2020 |
| APPL NO | 16/927739 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Electric Digital Data Processing G06F 21/31 (20130101) G06F 21/34 (20130101) G06F 21/35 (20130101) G06F 2221/2149 (20130101) Transmission H04B 5/0031 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3247 (20130101) H04L 63/08 (20130101) Telephonic Communication H04M 1/67 (20130101) H04M 1/72463 (20210101) Original (OR) Class Wireless Communication Networks H04W 4/80 (20180201) H04W 12/04 (20130101) H04W 12/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Nuclear Regulatory Commission (NRC)
| US 11123428 | Garner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana); Nanovis, LLC (Columbia City, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana); Nanovis, LLC (Columbia City, Indiana) |
| INVENTOR(S) | Allen Lawrence Garner (West Lafayette, Indiana); Ram Anand Vadlamani (West Lafayette, Indiana); David Alan Detwiler (Columbia City, Indiana) |
| ABSTRACT | Provided is a method of reducing a number of viable microbes, including contacting microbes with an antibiotic compound and applying pulses of electricity having a duration of between about 50 nanoseconds and about 900 nanoseconds. The pulses of electricity may have an intensity between about 20 kV/cm and about 40 kV/cm. The pulses of electricity may be applied at a frequency of between about 0.1 Hz and about 10 Hz. The microbes may be a gram-negative or a gram-positive strain of bacteria and the antibiotic may be applied at a concentration for a duration, wherein applying the antibiotic to the strain at the concentration for the duration does not reduce a viable number of bacteria of the strain as much, or at all, when the pulses of electricity are not also applied. |
| FILED | Wednesday, August 12, 2020 |
| APPL NO | 16/991284 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/341 (20130101) A61K 31/496 (20130101) A61K 31/575 (20130101) A61K 31/702 (20130101) A61K 31/5377 (20130101) A61K 31/7048 (20130101) A61K 38/14 (20130101) A61K 41/0023 (20130101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/32 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 13/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11127233 | Tartal et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | William Albert Tartal (Baltimore, Maryland); Gabriel Michael Yessin (Arlington, Virginia); Robert E. Dalton, Jr. (Greenville, South Carolina) |
| ABSTRACT | Locking systems and devices and methods for using the systems and devices are provided. A locking system may include a receptacle having a lock and an electronic credential. If the electronic credential is brought into proximity of the receptacle, then a key can be used to open the lock. The electronic credential can be incorporated into a vehicle or into a handheld device. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 16/580597 |
| ART UNIT | 2683 — Telemetry and Code Generation Vehicles and System Alarms |
| CURRENT CPC | Locks; Accessories Therefor; Handcuffs E05B 47/026 (20130101) Time or Attendance Registers; Registering or Indicating the Working of Machines; Generating Random Numbers; Voting or Lottery Apparatus; Arrangements, Systems or Apparatus for Checking Not Provided for Elsewhere G07C 9/00309 (20130101) Original (OR) Class G07C 9/00912 (20130101) G07C 2009/00396 (20130101) G07C 2009/00769 (20130101) G07C 2009/00968 (20130101) G07C 2209/63 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11125106 | Pratt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | William S. Pratt (West Hartford, Connecticut); Ryan M. Stanley (Quaker Hill, Connecticut); Adam Hart (East Hampton, Connecticut) |
| ABSTRACT | A synchronizing ring assembly includes a synchronizing ring portion that has a first and a second distal end, the first and the second distal end each form an integrated surge bumper. |
| FILED | Thursday, September 05, 2019 |
| APPL NO | 16/561540 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 17/162 (20130101) Original (OR) Class Non-positive-displacement Pumps F04D 29/542 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11127145 | Ely |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Richard W. Ely (Lewisville, Texas) |
| ABSTRACT | Discussed herein are devices, systems, and methods for image processing. A method can include generating a synthetic image based on a two-dimensional (2D) image of the geographical region, performing a coarse registration to grossly, register the synthetic image to the 2D image, and performing a fine registration following the coarse registration to improve the registration between the synthetic image and the 2D image. |
| FILED | Wednesday, July 10, 2019 |
| APPL NO | 16/507798 |
| ART UNIT | 2611 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/20 (20130101) G06T 3/0068 (20130101) G06T 7/13 (20170101) G06T 7/32 (20170101) Original (OR) Class G06T 7/33 (20170101) G06T 7/136 (20170101) G06T 2207/10028 (20130101) G06T 2207/10032 (20130101) G06T 2207/20016 (20130101) G06T 2207/20221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, September 21, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page