FedInvent™ Patents
Patent Details for Tuesday, November 02, 2021
This page was updated on Tuesday, November 02, 2021 at 04:56 PM GMT
Department of Health and Human Services (HHS)
| US 11160458 | Rogers et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | John A. Rogers (Champaign, Illinois); Li Gao (Urbana, Illinois); Viktor Malyarchuk (Urbana, Illinois); Richard Chad Webb (Urbana, Illinois) |
| ABSTRACT | Provided are tissue-mounted devices and methods for monitoring a thermal transport property (e.g., thermal conductivity, thermal diffusivity, heat capacity) of tissue, such as skin. The devices conformally mount to the tissue and have one or more thermal actuators and a plurality of sensors. The actuator applies heat to the tissue and the sensors to detect a spatio temporal distribution of a physiological tissue parameter or physical property resulting from the heating. This spatio temporal information may be correlated with a rate, velocity and/or direction of blood flow, the presence of a vascular occlusion, circulation changes due to inflammation, hydration level and other physiological parameters. |
| FILED | Tuesday, August 11, 2015 |
| APPL NO | 15/501379 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/015 (20130101) Original (OR) Class A61B 5/028 (20130101) A61B 5/0048 (20130101) A61B 5/0205 (20130101) A61B 5/0261 (20130101) A61B 5/318 (20210101) A61B 5/369 (20210101) A61B 5/389 (20210101) A61B 5/0537 (20130101) A61B 5/683 (20130101) A61B 5/02007 (20130101) A61B 5/4875 (20130101) A61B 5/6802 (20130101) A61B 5/6824 (20130101) A61B 5/6832 (20130101) A61B 2560/04 (20130101) A61B 2562/12 (20130101) A61B 2562/028 (20130101) A61B 2562/046 (20130101) A61B 2562/164 (20130101) A61B 2562/0271 (20130101) A61B 2562/0285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160470 | Tromberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Bruce J. Tromberg (Irvine, California); Kyle Cutler (Irvine, California); Chris Van Wagenen (Irvine, California); Seung-ha Lee (Irvine, California); Thomas O'Sullivan (Irvine, California); Gopi Meenakshisundaram (Irvine, California); Aditi Majumder (Irvine, California); Albert Cerussi (Irvine, California) |
| ABSTRACT | In accordance with various embodiments herein, disclosed herein is an apparatus comprising an imaging probe-based device operably linked to an automated tracking system. Furthermore, in various embodiments, the apparatus may be used to track the position and movement of a handheld imaging probe, including with respect to a subject's 3D surface profile. In one embodiment, a device may be used to track the position and movement of a handheld imaging probe with respect to a subject's 3D surface profile, while simultaneously acquiring optical data. |
| FILED | Tuesday, May 31, 2016 |
| APPL NO | 15/169426 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/062 (20130101) A61B 5/064 (20130101) A61B 5/065 (20130101) A61B 5/067 (20130101) Original (OR) Class A61B 5/0075 (20130101) A61B 5/1127 (20130101) A61B 5/1128 (20130101) A61B 2560/0223 (20130101) A61B 2562/0219 (20130101) A61B 2562/0223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160476 | Scherer et al. |
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| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California); THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire) |
| INVENTOR(S) | Axel Scherer (Pasadena, California); Meisam Honarvar Nazari (Pasadena, California); Muhammad Mujeeb-U-Rahman (Pasadena, California); Mehmet Sencan (Pasadena, California); Arti Gaur (Pasadena, California) |
| ABSTRACT | A fully integrated small size implantable sensing device is described, which can include a sensor and an electronic circuit to interface with the sensor and communicate with an external device. Various fabrication methods for the sensing device are described, including provision of wells, created using same fabrication technology as the electronic circuit, to contain electrodes of the sensor and corresponding functionalization chemicals. Such implantable sensing device can be used for a variety of electrochemical measuring applications within a living body as well as actuation by injecting a current into the living body. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 16/437890 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0031 (20130101) A61B 5/076 (20130101) A61B 5/1451 (20130101) A61B 5/1459 (20130101) A61B 5/1473 (20130101) Original (OR) Class A61B 5/4839 (20130101) A61B 5/14532 (20130101) A61B 5/14546 (20130101) A61B 5/14735 (20130101) A61B 5/14865 (20130101) A61B 17/3468 (20130101) A61B 2560/0219 (20130101) A61B 2562/04 (20130101) A61B 2562/028 (20130101) A61B 2562/125 (20130101) A61B 2562/0209 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/172 (20130101) A61M 5/1723 (20130101) A61M 5/14276 (20130101) A61M 2205/3523 (20130101) A61M 2205/8237 (20130101) A61M 2207/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160488 | Neitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington); UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | Universty of Washington (Seattle, Washington); University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| INVENTOR(S) | Jay Neitz (Seattle, Washington); Maureen Neitz (Seattle, Washington); James A. Kuchenbecker (Seattle, Washington); William W. Hauswirth (Gainesville, Florida) |
| ABSTRACT | The present invention provides reagents and methods for modulating cone photoreceptor activity, and devices for assessment of cone photoreceptor activity. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 15/939674 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0036 (20180801) A61B 5/0048 (20130101) A61B 5/398 (20210101) Original (OR) Class A61B 5/4836 (20130101) A61B 5/4848 (20130101) A61B 5/6821 (20130101) A61B 5/7225 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 48/0058 (20130101) A61K 48/0075 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0622 (20130101) A61N 2005/0652 (20130101) A61N 2005/0661 (20130101) A61N 2005/0663 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/85 (20130101) C12N 15/86 (20130101) C12N 2750/14132 (20130101) C12N 2750/14143 (20130101) C12N 2799/025 (20130101) C12N 2830/008 (20130101) C12N 2830/42 (20130101) C12N 2840/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160489 | Rogers et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); WASHINGTON UNIVERSITY IN ST. LOUIS (St. Louis, Missouri) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | John A. Rogers (Wilmette, Illinois); Michael Raymond Bruchas (St. Louis, Missouri); Jaewoong Jeong (Champaign, Illinois); Jordan Gary McCall (St. Louis, Missouri) |
| ABSTRACT | Provided are implantable, injectable and/or surface mounted biomedical devices and related methods for interfacing with a target tissue. The devices have a substrate, one or more microfluidic channels embedded in or supported by the substrate and a fluid actuator in operational communication with one or more reservoirs and responsive to a wireless control signal. The components of the device are specially configured and packaged to be ultra-thin and mechanically compliant. In some embodiments, the devices are self-powered and fully implantable. The devices can be shaped to provide injection in a minimally invasive manner, thereby avoiding unnecessary tissue damage and providing a platform for long-term implantation for interfacing with biological tissue. |
| FILED | Friday, July 01, 2016 |
| APPL NO | 15/738043 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/0006 (20130101) A61B 5/0008 (20130101) A61B 5/24 (20210101) A61B 5/0031 (20130101) A61B 5/0084 (20130101) A61B 5/145 (20130101) A61B 5/291 (20210101) A61B 5/685 (20130101) A61B 5/4064 (20130101) Original (OR) Class A61B 5/4836 (20130101) A61B 5/6844 (20130101) A61B 5/6868 (20130101) A61B 5/14503 (20130101) A61B 2560/0412 (20130101) A61B 2562/12 (20130101) A61B 2562/028 (20130101) A61B 2562/164 (20130101) A61B 2562/0285 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14276 (20130101) A61M 2205/3327 (20130101) A61M 2205/3561 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160492 | Butterworth |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Ian Butterworth (Somerville, Massachusetts) |
| ABSTRACT | A finger insert for use with a nailfold imaging device includes a housing to receive the user's finger and an immersion substance (e.g., immersion oil), and a deformable pad that holds the user's finger in place during imaging, as well as prevent bubble formation in the substance. The housing includes a transparent wall to facilitate imaging of the finger. The transparent wall includes multiple angled portions that prevent or reduce contact between the nailfold and the wall, to ensure sufficient blood flow through the nailfold region for imaging. |
| FILED | Tuesday, May 26, 2020 |
| APPL NO | 16/882966 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0077 (20130101) A61B 5/0082 (20130101) A61B 5/0261 (20130101) A61B 5/449 (20130101) Original (OR) Class A61B 5/702 (20130101) A61B 5/02241 (20130101) A61B 5/6826 (20130101) A61B 2562/16 (20130101) A61B 2562/146 (20130101) A61B 2562/164 (20130101) A61B 2562/168 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 2009/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160664 | Cavanagh et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Peter R. Cavanagh (Seattle, Washington); Scott Telfer (Seattle, Washington) |
| ABSTRACT | A device for use during an arthroplasty procedure of a joint of a patient, the joint extending between a first joint end of a first bone and an abutting second joint end of a second bone of the patient. The device includes first and second components that can be mated together. The first component includes an attachment fitting configured for disposing over the first joint end of the first bone and a stem extending from the attachment fitting and suitable for extending along an intra-medullary canal of the first bone. The second component includes an end plate configured to mate with the attachment fitting and a longitudinal plate extending from the end plate and configured for disposing along a medial, longitudinal surface of the first bone. The device also includes at least one fastener for coupling the longitudinal plate to the first bone. |
| FILED | Tuesday, July 25, 2017 |
| APPL NO | 16/633141 |
| ART UNIT | 3774 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/1775 (20161101) A61B 17/7291 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/4225 (20130101) Original (OR) Class A61F 2/4241 (20130101) A61F 2/4606 (20130101) A61F 2002/4233 (20130101) A61F 2002/30578 (20130101) A61F 2002/30878 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160767 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The George Washington University, a Congressionally Chartered Not-For-Profit Corporation (Washington, District of Columbia) |
| ASSIGNEE(S) | The George Washington University, a Congressionally Chartered Not-For-Profit Corporation (Washington, District of Columbia) |
| INVENTOR(S) | Chi-Wei Chen (Silver Spring, Maryland); Yongming Li (Liaoning, China PRC); Zhiyong Han (Fairfax, Virginia); Wenge Zhu (Germantown, Maryland) |
| ABSTRACT | The present disclosure provides methods, pharmaceutical compositions, dosing regimens, and kits comprising 4,4′-trans-dihydroxystilbene (DHS), including methods of treating cancer in a subject and methods of decreasing or reversing resistance to a DNA damaging agent in a subject. |
| FILED | Wednesday, April 11, 2018 |
| APPL NO | 16/604948 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) Original (OR) Class A61K 33/243 (20190101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160769 | Gudas et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, New York) |
| ASSIGNEE(S) | Cornell University (New York, New York) |
| INVENTOR(S) | Lorraine J Gudas (New York, New York); Yannick Benoit (Ontario, Canada); Ronald Perez (Somerset, New Jersey); Xiao-Han Tang (Staten Island, New York); Steven Trasino (Brooklyn, New York) |
| ABSTRACT | This invention relates to pharmaceutical compositions and methods for treating (including managing) or preventing metabolic syndrome related conditions using one or more RAR e.g., RAR agonists. Such conditions include, but are not limited to, diseases in pancreas, liver, kidney, testes, muscle, or adipose tissue, as well as other organs that are associated with high fat diet and/or vitamin A deficiency, as well as other conditions associated with abnormal level of triglyceride, cholesterol and/or glucose. |
| FILED | Friday, January 16, 2015 |
| APPL NO | 15/112159 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/07 (20130101) Original (OR) Class A61K 31/192 (20130101) A61K 31/426 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 3/04 (20180101) A61P 3/06 (20180101) A61P 3/10 (20180101) A61P 9/00 (20180101) A61P 13/12 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160770 | Kelley et al. |
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| FUNDED BY |
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| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| INVENTOR(S) | Mark R. Kelley (Zionsville, Indiana); Michael R. Vasko (Indianapolis, Indiana) |
| ABSTRACT | Compounds, compositions, and formulations, and accompanying methods useful for treating disorders arising from oxidative DNA damage, including oxidative DNA damage resulting from ionizing radiation or other therapy are described herein. |
| FILED | Wednesday, March 18, 2020 |
| APPL NO | 16/822466 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/16 (20130101) A61K 31/19 (20130101) A61K 31/20 (20130101) A61K 31/21 (20130101) A61K 31/122 (20130101) Original (OR) Class A61K 31/165 (20130101) A61K 31/192 (20130101) A61K 31/495 (20130101) A61K 31/5375 (20130101) Acyclic or Carbocyclic Compounds C07C 66/00 (20130101) C07C 235/78 (20130101) Heterocyclic Compounds C07D 295/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160775 | Gurtner et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | Geoffrey C. Gurtner (Portola Valley, California); Jayakumar Rajadas (Cupertino, California); Michael Gabriel Galvez (Palo Alto, California); Evgenios Neofytou (Stanford, California) |
| ABSTRACT | Compositions and methods are provided for the prevention and treatment of chronic wounds, including, without limitation, pressure ulcers and diabetic ulcers, by transdermal delivery of an agent that increases activity of HIF-1α in the wound. |
| FILED | Wednesday, July 08, 2020 |
| APPL NO | 16/923857 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0014 (20130101) A61K 9/1075 (20130101) A61K 9/7023 (20130101) A61K 9/7053 (20130101) A61K 9/7069 (20130101) A61K 31/16 (20130101) Original (OR) Class A61K 47/26 (20130101) A61K 47/32 (20130101) A61K 47/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160823 | Jones et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | University of Massachusetts (Boston, Massachusetts) |
| INVENTOR(S) | Peter L. Jones (Carson City, Nevada); Michael R. Green (Boylston, Massachusetts) |
| ABSTRACT | The disclosure relates to methods and compositions for regulating expression of DUX4. In some aspects, methods described by the disclosure are useful for treating a disease associated with aberrant DUX4 expression (e.g., facioscapulohumeral muscular dystrophy). |
| FILED | Tuesday, November 07, 2017 |
| APPL NO | 16/347688 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7105 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/90 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2310/20 (20170501) C12N 2740/16043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160826 | Demorrow et al. |
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| FUNDED BY |
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| APPLICANT(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Sharon Demorrow (Temple, Texas); Matthew MacMillin (Harker Height, Texas) |
| ABSTRACT | The present disclosure is concerned with cholesterol lowering agents including, but not limited to, statins and cyclodextrins, for the treatment of hepatic encephalopathy. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 16/663217 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/724 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160833 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seatlle, Washington) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seattle, Washington) |
| INVENTOR(S) | Yvonne Y. Chen (Los Angeles, California); Eugenia Zah (Los Angeles, California); Michael C. Jensen (Seattle, Washington) |
| ABSTRACT | A CD19-OR-CD20 chimeric antigen receptor (CAR) protein construct is provided. Also provided are nucleic acids encoding the CD19-OR-CD20 CAR; and methods of use, e.g. in the treatment of B cell malignancies. The CD19-OR-CD20 CAR of the invention is a bispecific CAR that can trigger T-cell activation upon detection of either CD19 or CD20 (or both). It is a single molecule that confers two-input recognition capability upon human T cells engineered to stably express this CAR. |
| FILED | Tuesday, September 22, 2020 |
| APPL NO | 17/028701 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70596 (20130101) C07K 16/46 (20130101) C07K 16/2803 (20130101) C07K 16/2887 (20130101) C07K 2317/31 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160834 | Prockop et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| ASSIGNEE(S) | THE TEXAS A and M UNIVERSITY SYSTEM (College Station, Texas) |
| INVENTOR(S) | Darwin J. Prockop (Philadelphia, Pennsylvania); Dong-Ki Kim (College Station, Texas); Hidetaka Nishida (College Station, Texas); Askok K. Shetty (Austin, Texas) |
| ABSTRACT | Preparations comprising an enriched population of extracellular vesicles (nEVs) having a negatively charged surface, and that are CD81+ and CD9−, are provided. Improved processes and methods for producing an enriched population of nEVs from non-murine cells, especially human origin cells and/or tissues, are disclosed. Therapeutic methods for using the preparations, including for reducing brain inflammation and treatment of various pathologies associated with brain inflammation, such as by intravenous or intranasal administration, are also described. Methods and preparations for reducing brain inflammation associated with traumatic brain injury (TBI) are also disclosed. A method for treating a patient having suffered a mild traumatic injury (mTMI), or concussion, such as a sports-related head injury, is also disclosed. The nEVs are also demonstrated to reduce the expression level of IL-Iβ in brain tissue of an animal having had traumatic brain injury. Methods for improving cognitive function and performance in animals after a traumatic brain injury is also demonstrated using the preparations of nEVs disclosed herein. |
| FILED | Thursday, April 28, 2016 |
| APPL NO | 15/570316 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/12 (20130101) A61K 35/28 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) A61P 43/00 (20180101) Peptides C07K 5/06034 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0663 (20130101) C12N 2500/95 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160851 | Shea et al. |
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| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| INVENTOR(S) | Lonnie D. Shea (Evanston, Illinois); Stephen D. Miller (Evanston, Illinois); Jonathan Woon Teck Yap (Evanston, Illinois); Daniel R. Getts (Northbrook, Illinois); Derrick McCarthy (Evanston, Illinois) |
| ABSTRACT | The present invention provides compositions comprising peptide-coupled biodegradable poly(lactide-co-glycolide) (PLG) particles. In particular, PLG particles are surface-functionalized to allow for coupling of peptide molecules to the surface of the particles (e.g., for use in eliciting induction of immunological tolerance). |
| FILED | Wednesday, March 08, 2017 |
| APPL NO | 15/453807 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/1647 (20130101) A61K 9/5153 (20130101) A61K 39/00 (20130101) A61K 39/0008 (20130101) Original (OR) Class A61K 47/58 (20170801) A61K 47/6911 (20170801) A61K 47/6935 (20170801) A61K 47/6937 (20170801) A61K 2039/577 (20130101) A61K 2039/622 (20130101) A61K 2039/55555 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160853 | Disis et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATON (Seattle, Washington) |
| INVENTOR(S) | Mary L. Disis (Renton, Washington); Denise Cecil (Shoreline, Washington); Meredith Slota (Seattle, Washington) |
| ABSTRACT | The compositions described herein include an epitope of a peptide that may elicit an immune response in a subject following administration. The compositions may comprise nucleic acids. The compositions may comprise peptides. The methods described herein include administering a composition comprising an epitope of a peptide to a subject in need thereof. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/370683 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/00115 (20180801) A61K 39/001103 (20180801) A61K 39/001106 (20180801) A61K 39/001129 (20180801) A61K 39/001152 (20180801) A61K 48/00 (20130101) A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/572 (20130101) Peptides C07K 14/71 (20130101) C07K 14/705 (20130101) C07K 14/4702 (20130101) C07K 14/70567 (20130101) C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/104 (20130101) Enzymes C12Y 203/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160859 | Crawford et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida); CORNELL RESEARCH FOUNDATION, INC. (Ithaca, New York); The Government of The United States of America as represented by The Secretary of The Department of Health and Human Services. Centers for Disease Control and Prevention (Atlanta, Georgia) |
| ASSIGNEE(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (Gainesville, Florida); CORNELL RESEARCH FOUNDATION, INC. (Ithaca, New York); THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES, CENTERS FOR DISEASE CONTROL AND PREVENTION (Atlanta, Georgia) |
| INVENTOR(S) | Patti Cynthia Crawford (Gainesville, Florida); Paul J. Gibbs (Gainesville, Florida); Edward J. Dubovi (Ithaca, New York); Ruben Omar Donis (Atlanta, Georgia); Jacqueline Katz (Atlanta, Georgia); Alexander I. Klimov (Atlanta, Georgia); Nallakannu P. Lakshmanan (Millsboro, Delaware); Melissa Anne Lum (Millsboro, Delaware); Daniel Ghislena Emiel Goovaerts (Boxmeer, Netherlands); Mark William Mellencamp (Desoto, Kansas); Nancy J. Cox (Atlanta, Georgia); William L. Castleman (Gainesville, Florida) |
| ABSTRACT | The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention. |
| FILED | Friday, April 12, 2019 |
| APPL NO | 16/382429 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/53 (20130101) A61K 2039/552 (20130101) A61K 2039/5252 (20130101) A61K 2039/55555 (20130101) A61K 2039/55566 (20130101) Peptides C07K 14/005 (20130101) C07K 16/1018 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2710/24043 (20130101) C12N 2760/16121 (20130101) C12N 2760/16122 (20130101) C12N 2760/16134 (20130101) C12N 2760/16151 (20130101) C12N 2760/16171 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160875 | Cui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Honggang Cui (Lutherville, Maryland); Alfredo Quinones-Hinojosa (Bel Air, Maryland) |
| ABSTRACT | The present invention provides compositions comprising at least one biologically active agent (D) chemically conjugated to a peptide or oligopeptide with overall hydrophilicity (Pep). In some embodiments, the composition comprises D-Pep wherein the biologically active agents are linked to the Pep molecule via an chemical linker, such as amino acid linker. These compositions can be mixed with the other compositions to provide mixtures of nanofiber hydrogel structures that also can be used to locally deliver biologically active agents to tissues of interest. The methods and compositions disclosed herein are useful for sustained drug release when administered in situ to the tissue of interest. |
| FILED | Thursday, June 16, 2016 |
| APPL NO | 15/736818 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/196 (20130101) A61K 31/337 (20130101) A61K 31/407 (20130101) A61K 47/64 (20170801) A61K 47/6903 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160979 | Giuffrida et al. |
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| FUNDED BY |
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| APPLICANT(S) | Great Lakes NeuroTechnologies Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | Great Lakes NeuroTechnologies Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Joseph P. Giuffrida (Hinckley, Ohio); Dustin A. Heldman (Shaker Heights, Ohio); Thomas O. Mera (Columbus, Ohio) |
| ABSTRACT | A system and method for tuning the parameters of a therapeutic medical device comprises a movement measurement data acquisition system capable of wireless transmission; processing comprising kinematic feature extraction, a scoring algorithm trained using scores from expert clinicians, a therapeutic device parameter setting adjustment suggestion algorithm preferably trained using the parameter setting adjustment judgments of expert clinicians; and a display and/or means of updating the parameter settings of the treatment device. The invention facilitates the treatment of movement disorders including Parkinson's disease, essential tremor and the like by optimizing deep brain stimulation (DBS) parameter settings, eliminating as much as possible motor symptoms and reducing time and costs of surgical and outpatient procedures and improving patient outcomes. In preferred embodiments, the system provides recommendations for treatment which may be semi-automatically or automatically applied to update the parameter settings of a treatment device such as a DBS implant. |
| FILED | Monday, April 24, 2017 |
| APPL NO | 15/494930 |
| ART UNIT | 3626 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36067 (20130101) Original (OR) Class A61N 1/36139 (20130101) A61N 1/37217 (20130101) A61N 1/37247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161827 | Zhang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston College (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | The Trustees of Boston College (Chesnut Hill, Morocco) |
| INVENTOR(S) | Xiao-Xiang Zhang (Newton, Massachusetts); Kai Lang (Boston, Massachusetts) |
| ABSTRACT | In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on sequential combination of enantiodifferentiative H-atom abstraction and stereoretentive radical substitution. Also disclosed is an asymmetric system for stereoselective synthesis of strained 5-membered cyclic sulfamides via radical 1,5-C—H amination of sulfamoyl azides. The disclosed metalloradical system can control the degree and sense of asymmetric induction in the catalytic radical C—H amination in a systematic manner. The disclosed system is applicable to a broad scope of substrates with different types of C(sp3)—H bonds and exhibits reactivity and selectivity, providing access to both enantiomers of useful 5-membered cyclic sulfamides in a highly enantioenriched form. Also disclosed are catalysts useful in these processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Monday, April 06, 2020 |
| APPL NO | 16/840879 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/183 (20130101) B01J 2231/4283 (20130101) B01J 2531/845 (20130101) Heterocyclic Compounds C07D 285/10 (20130101) Original (OR) Class C07D 487/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161831 | Tweardy et al. |
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| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | David J. Tweardy (Houston, Texas); Moses M. Kasembeli (Houston, Texas); Marvin X. Xu (Kaifeng, China PRC); Thomas Kristian Eckols (Houston, Texas) |
| ABSTRACT | Embodiments of the invention include methods of treating, preventing, and/or reduce the risk or severity of a condition selected from the group consisting of muscle wasting, muscle weakness, cachexia, and a combination thereof in an individual in need thereof. In some embodiments, particular small molecules are employed for treatment, prevention, and/or reduction in the risk of muscle wasting. In at least particular cases, the small molecules are inhibitors of STAT3. |
| FILED | Tuesday, April 14, 2020 |
| APPL NO | 16/848661 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/42 (20130101) A61K 31/45 (20130101) A61K 31/47 (20130101) A61K 31/145 (20130101) A61K 31/357 (20130101) A61K 31/381 (20130101) A61K 31/404 (20130101) A61K 31/415 (20130101) A61K 31/428 (20130101) A61K 31/454 (20130101) A61K 31/513 (20130101) A61K 31/4035 (20130101) A61K 31/4164 (20130101) A61K 31/4196 (20130101) A61K 31/4406 (20130101) A61K 31/4704 (20130101) A61K 31/4709 (20130101) A61K 45/06 (20130101) Acyclic or Carbocyclic Compounds C07C 311/08 (20130101) C07C 311/10 (20130101) C07C 311/13 (20130101) C07C 311/21 (20130101) C07C 311/24 (20130101) C07C 311/29 (20130101) C07C 311/44 (20130101) C07C 323/49 (20130101) C07C 381/06 (20130101) C07C 2101/14 (20130101) C07C 2102/10 (20130101) C07C 2601/14 (20170501) C07C 2602/10 (20170501) Heterocyclic Compounds C07D 213/71 (20130101) C07D 215/36 (20130101) C07D 231/18 (20130101) C07D 319/18 (20130101) C07D 333/34 (20130101) Original (OR) Class Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161842 | Gray et al. |
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| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Nathanael Gray (Boston, Massachusetts); Jaebong Jang (Boston, Massachusetts); Dries De Clercq (Boston, Massachusetts); Michael Eck (Boston, Massachusetts); Pasi Janne (Needham, Massachusetts) |
| ABSTRACT | The present application provides bifunctional compounds of Formula (I): which act as protein degradation inducing moieties for EGFR and/or a mutant thereof. The present application also describes methods for the targeted degradation of EGFR and/or a mutant thereof through the use of the bifunctional compounds that link a ubiquitin ligase-binding moiety to a ligand that is capable of binding to EGFR and/or a mutant thereof which can be utilized in the treatment of disorders modulated by EGFR or a mutant thereof. |
| FILED | Monday, September 30, 2019 |
| APPL NO | 16/588750 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/18 (20130101) A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 417/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161859 | Baran et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| INVENTOR(S) | Phil Baran (San Diego, California); Chao Li (San Diego, California); Jie Wang (San Diego, California); Arnab Kumar Chatterjee (San Diego, California); Manoj Kumar (San Diego, California); Shan Yu (San Diego, California); Kristen Ann Johnson (Santee, California); Tian Qin (Dallas, Texas); Ming Shang (San Diego, California) |
| ABSTRACT | The invention is directed to methods of converting a carboxylic acid group in a compound, via a redox active ester, to a corresponding boronic ester by treatment with bis(pinacolato)diboron-alkyllithium complex in the presence of a ligand, a Ni(ll) salt or a copper salt, and an Mg(ll) salt, in the presence of an alkyllithium or a lithium hydroxide or alkoxide salt. The product pinacolato boronate ester can be cleaved to provide a boronic acid. The invention is also directed to methods of preparing various compounds of medical value comprising boronic acid groups, and to novel boronic-acid containing compounds of medicinal value, including an atorvastatin boronic acid analog, a vancomycin aglycone boronic acid analog, and boronic acid containing elastase inhibitors mCBK319, mCBK320, mCBK323, and RPX-7009. |
| FILED | Wednesday, March 14, 2018 |
| APPL NO | 16/495907 |
| ART UNIT | 1622 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/0212 (20130101) B01J 2231/344 (20130101) B01J 2531/16 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 47/00 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/027 (20130101) Original (OR) Class Peptides C07K 7/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161865 | Mach et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Robert H. Mach (Wallingford, Pennsylvania); Sean Reilly (Philadelphia, Pennsylvania); Mehran Makvandi (Philadelphia, Pennsylvania); Kuiying Xu (Wallingford, Pennsylvania); Daniel A. Pryma (Bryn Mawr, Pennsylvania); Roger A. Greenberg (Bala Cynwyd, Pennsylvania) |
| ABSTRACT | The present disclosure relates to compounds of Formula I and II, wherein R1-R20 and FL are defined herein. Also provided are methods of targeting alpha-radiation to poly(ADP-ribose)polymerase 1 (PARP-1) enzyme expression, reducing proliferation of cancer cells, reducing proliferation of cancer cells, detecting intact and enzymatically active poly(ADP-ribose)polymerase 1 (PARP-1) enzyme expression, detecting PARP-1 enzyme expression in a subjects tissue sample, monitoring cancer treatment in a subject, or detecting a PARP-1 receptive cancer in a subject. |
| FILED | Thursday, May 24, 2018 |
| APPL NO | 16/616049 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/10 (20130101) A61K 51/047 (20130101) Heterocyclic Compounds C07D 487/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/027 (20130101) C07F 13/00 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57496 (20130101) G01N 2333/91142 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161868 | Chen et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Xi Chen (Davis, California); An Xiao (Davis, California); Anoopjit Kooner (Davis, California); Abhishek Santra (Davis, California); Ajit Varki (San Diego, California); Hai Yu (Davis, California); Lee-Ping Wang (Davis, California); Wanqing Li (Davis, California) |
| ABSTRACT | The present invention provides N-acetyl derivatives of sialic acids, including N-acetyl derivatives of Neu5Ac and Neu5Gc. Methods for preparing related precursors and a variety of sialosides are also disclosed. |
| FILED | Tuesday, May 21, 2019 |
| APPL NO | 16/418758 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/04 (20130101) Original (OR) Class C07H 15/12 (20130101) C07H 15/14 (20130101) C07H 15/203 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/28 (20130101) C12P 19/44 (20130101) C12P 19/64 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161895 | Haynes et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Barton F. Haynes (Durham, North Carolina); Kevin J. Wiehe (Durham, North Carolina); Mattia Bonsignori (Durham, North Carolina) |
| ABSTRACT | The invention is directed to methods to identify improbable mutations in the heavy or light chain variable domain of an antibody, methods to identify antigens which bind to antibodies comprising such improbable mutations, and methods of using such antigens to induce immune responses. |
| FILED | Tuesday, October 03, 2017 |
| APPL NO | 16/337264 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/55 (20130101) C07K 2317/56 (20130101) C07K 2317/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161899 | Muir et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Tom W. Muir (Princeton, New Jersey); Miquel Vila-Perello (Princeton, New Jersey); Zhihua Liu (Plainsborough, New Jersey); Neel H. Shah (Princeton, New Jersey) |
| ABSTRACT | Disclosed herein are split inteins, fused proteins of split inteins, and methods of using split inteins to efficiently purify and modify proteins of interest. |
| FILED | Thursday, November 21, 2019 |
| APPL NO | 16/690213 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/195 (20130101) C07K 16/18 (20130101) Original (OR) Class C07K 2319/50 (20130101) C07K 2319/92 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/93 (20130101) C12N 15/62 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) C12P 21/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162073 | Shah et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Dhvanit I. Shah (Malden, Massachusetts); George Q. Daley (Weston, Massachusetts) |
| ABSTRACT | Described in the present application are methods for preparing populations of hematopoietic stem cells (HSCs), e.g., autologous and/or allogenic HSCs, using mechanical stretching or Trpv4 agonisists, and methods of use of the HSCs in transplantation. In some embodiments, the methods include providing a population comprising hemogenic endothelial (HE) cells, and (i) contacting the HE cells with an amount of an agonist of transient receptor potential cation channel-subfamily vanilloid member 4 (Trpv4); and/or (ii) subjecting the cells to cyclic 2-dimensional stretching, for a time and under conditions sufficient to stimulating endothelial-to-HSC transition. Also provided herein are methods for treating subjects who have, bone marrow, metabolic, and immune diseases; the methods include administering to the subject a therapeutically effective amount of hematopoietic stem cells (HSCs) obtained by a method described herein. |
| FILED | Friday, December 02, 2016 |
| APPL NO | 15/781034 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) A01K 2207/12 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) Original (OR) Class C12N 2501/999 (20130101) C12N 2506/00 (20130101) C12N 2506/28 (20130101) C12N 2506/45 (20130101) C12N 2533/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162074 | Hematti et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Peiman Hematti (Middleton, Wisconsin); Jaehyup Kim (Madison, Wisconsin) |
| ABSTRACT | The invention relates to purified, tissue-specific progenitors, methods of making and using such tissue-specific progenitors. |
| FILED | Monday, June 11, 2018 |
| APPL NO | 16/004633 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) A61K 2035/124 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) Original (OR) Class C12N 5/0676 (20130101) C12N 5/0693 (20130101) C12N 5/0694 (20130101) C12N 2502/1157 (20130101) C12N 2502/1358 (20130101) C12N 2506/02 (20130101) C12N 2506/22 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162079 | Schrepfer et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sonja Schrepfer (Burlingame, California); Tobias Deuse (Burlingame, California) |
| ABSTRACT | The invention discloses for the first time pluripotent cells, including hypoimmune pluripotent ABO blood type O Rhesus Factor negative (HIPO−) cells, that evade rejection by the host allogeneic immune system and avoid blood antigen type rejection. The HIPO− cells comprise reduced HLA-I and HLA-II expression, increased CD47 expression, and a universal blood group O Rh− (“O−”) blood type. The universal blood type is achieved by eliminating ABO blood group A and B antigents as well as eliminating Rh factor expression, or by starting with an O− parent cell line. These new, novel HIPO− cells evade host immune rejection because they have an impaired antigen presentation capacity, protection from innate immune clearance, and lack blood group rejection. The cells of the invention also include O− pluripotent stem cells (iPSCO−) and O− embryonic stem cells (ESCO−). The invention further provides universally acceptable “off”-the-shelf pluripotent cells and derivatives thereof for generating or regenerating specific tissues and organs. |
| FILED | Saturday, May 09, 2020 |
| APPL NO | 16/870959 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0606 (20130101) C12N 5/0657 (20130101) C12N 5/0696 (20130101) Original (OR) Class C12N 2500/00 (20130101) C12N 2501/115 (20130101) C12N 2501/165 (20130101) C12N 2506/02 (20130101) C12N 2506/45 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162080 | Wimmer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State of University New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Eckard Wimmer (East Setauket, New York); Steve Skiena (Setauket, New York); Steffen Mueller (Kings Point, New York); Bruce Futcher (Stony Brook, New York); Dimitris Papamichail (Newtown, Pennsylvania); John Robert Coleman (Blauvelt, New York); Jeronimo Cello (Port Jefferson, New York) |
| ABSTRACT | This invention provides an attenuated virus which comprises a modified viral genome containing nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce synonymous deoptimized codons into the genome. The instant attenuated virus may be used in a vaccine composition for inducing a protective immune response in a subject. The invention also provides a method of synthesizing the instant attenuated virus. Further, this invention further provides a method for preventing a subject from becoming afflicted with a virus-associated disease comprising administering to the subject a prophylactically effective dose of a vaccine composition comprising the instant attenuated virus. |
| FILED | Monday, July 16, 2018 |
| APPL NO | 16/036348 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/13 (20130101) A61K 39/145 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2720/12361 (20130101) C12N 2740/15061 (20130101) C12N 2760/16061 (20130101) C12N 2760/16121 (20130101) C12N 2760/16134 (20130101) C12N 2760/16162 (20130101) C12N 2770/20061 (20130101) C12N 2770/24161 (20130101) C12N 2770/32061 (20130101) C12N 2770/32621 (20130101) C12N 2770/32634 (20130101) C12N 2770/32661 (20130101) C12N 2770/32662 (20130101) C12N 2770/32671 (20130101) C12N 2770/32721 (20130101) C12N 2770/32761 (20130101) C12N 2770/32762 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162083 | McInnes et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTH CAROLINA (Columbia, South Carolina) |
| ASSIGNEE(S) | University of South Carolina (Columbia, South Carolina) |
| INVENTOR(S) | Campbell McInnes (Irmo, South Carolina); Chad Beneker (Columbia, South Carolina) |
| ABSTRACT | Herein are described peptide-based compositions for modifying Raf kinase protein Dimerization. These compositions, treatments, and methods of use are directed to peptides that display a binding affinity for the dimer interface of a Raf kinase protein, methods for modifying Raf kinase dimerization, and methods for inhibiting tumor growth. An embodiment of the disclosure is a peptide generated by modifying an ordered sequence chosen from SEQ ID NO: 1 which corresponds to amino acids 503-521 of B-Raf kinase. The peptides disclosed herein include a modification to an ordered sequence of amino acids derived from SEQ ID NO: 1 that can improve or otherwise alter binding affinity of the peptide to the dimer interface. |
| FILED | Friday, June 14, 2019 |
| APPL NO | 16/441054 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/08 (20130101) C07K 14/82 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162090 | Goldberg et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Tony L. Goldberg (Madison, Wisconsin); Samuel D. Sibley (Madison, Wisconsin) |
| ABSTRACT | Metagenomic data are increasingly useful for detecting microbes, such as viruses and other microorganisms in a wide range of sample types. Methods and systems for isolating, detecting, and characterizing microbes in biological samples using metagenomic data are provided. Also disclosed are methods for identifying microbes in nucleic acid libraries. |
| FILED | Friday, September 01, 2017 |
| APPL NO | 15/694249 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1003 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/6806 (20130101) C12Q 1/6853 (20130101) C12Q 1/6869 (20130101) C12Q 1/6888 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 30/00 (20190201) G16B 50/00 (20190201) G16B 50/10 (20190201) G16B 50/30 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162092 | Yamamoto et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Masato Yamamoto (Minneapolis, Minnesota); Yoshiaki Miura (Roseville, Minnesota) |
| ABSTRACT | Described herein is a method that generally includes infecting a host cell with a rescue adenovirus, wherein the rescue adenovirus genome comprises a loxP site and encodes at least one marker, and wherein the host cell comprises a library of polynucleotides that complement the adenovirus genome marker and encode a detectable polypeptide; incubating the infected host cell under conditions effective to permit recombination between the adenovirus genome and one or more of the library polynucleotides and the production of recombinant adenovirus particles comprising at least on detectable polypeptide; and detecting the at least one detectable polypeptide. Also described are adenovirus libraries constructed using such a method. |
| FILED | Thursday, January 17, 2019 |
| APPL NO | 16/250282 |
| ART UNIT | 1699 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/1034 (20130101) Original (OR) Class C12N 15/1037 (20130101) C12N 2710/10043 (20130101) C12N 2710/10071 (20130101) C12N 2800/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162134 | Zong |
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| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Chenghang Zong (Houston, Texas) |
| ABSTRACT | Embodiments of the disclosure encompass highly sensitive and quantitative methods for single-cell sequencing of total RNA. In particular cases, methods utilize annealing of multiple primers to RNA, polytailing of single stranded DNA reverse transcribed therefrom, and utilization of bar codes in primers for amplification of amplicons produced from second strand synthesis. |
| FILED | Friday, March 31, 2017 |
| APPL NO | 16/088704 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1096 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6853 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162143 | He |
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| FUNDED BY |
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| APPLICANT(S) | The University of Kansas (Lawrence, Kansas); Kansas State University Research Foundation (Manhattan, Kansas) |
| ASSIGNEE(S) | The University of Kansas (Lawrence, Kansas); Kansas State University Research Foundation (Manhattan, Kansas) |
| INVENTOR(S) | Mei He (Gainesville, Florida) |
| ABSTRACT | Methods for producing engineered exosomes and other vesicle-like biological targets, including allowing a target vesicle-like structure to react and bind with immunomagnetic particles; capturing the immunomagnetic particle/vesicle complex by applying a magnetic field; further engineering the captured vesicles by surface modifying with additional active moieties or internally loading with active agents; and releasing the engineered vesicle-like structures, such as by photolytically cleaving a linkage between the particle and engineered vesicle-like structures, thereby releasing intact vesicle-like structures which can act as delivery vehicles for therapeutic treatments. |
| FILED | Wednesday, April 21, 2021 |
| APPL NO | 17/236561 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6901 (20170801) A61K 49/0097 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/015 (20130101) B03C 1/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5434 (20130101) G01N 33/54333 (20130101) G01N 2446/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162144 | Wolff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the USA as represented by the Secretary of the Dept. of Health and Human Services (Atlanta, Georgia) |
| ASSIGNEE(S) | The Government of The United States of America as represented by the Secretary of the Department of Health and Human Services (Atlanta, Georgia) |
| INVENTOR(S) | Bernard Wolff (Roswell, Georgia); Jonas M. Winchell (Lilburn, Georgia); Maureen Diaz (Atlanta, Georgia) |
| ABSTRACT | Methods for detecting presence of one or more of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Toxoplasma gondii, Moraxella catarrhalis, Escherichia coli, Shigella, Staphylococcus aureus, Pneumocystis jirovecii, Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Ureaplasma spp., Bartonella spp., Streptococcus agalactiae, and Neisseria meningitidis nucleic acids in a sample, such as a biological sample obtained from a subject, or an environmental sample, are provided. This disclosure also provides probes, primers, and kits for detecting one or more of Acinetobacter baumannii, Pseudomonas aeruginosa, Klebsiella pneumoniae, Toxoplasma gondii, Moraxella catarrhalis, Escherichia coli, Shigella, Staphylococcus aureus, Pneumocystis jirovecii, Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Ureaplasma spp., Bartonella spp., Streptococcus agalactiae, and Neisseria meningitidis in a sample. |
| FILED | Monday, August 06, 2018 |
| APPL NO | 16/056147 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6895 (20130101) C12Q 2600/16 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162886 | Kimmerling et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert J. Kimmerling (Cambridge, Massachusetts); Nicholas L. Calistri (Cambridge, Massachusetts); Scott R. Manalis (Cambridge, Massachusetts); Selim Olcum (Cambridge, Massachusetts); Mark M. Stevens (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for flowing particles, such as biological entities, in a fluidic channel(s) are generally provided. In some cases, the systems described herein are designed such that a single particle may be isolated from a plurality of particles and flowed into a fluidic channel (e.g., a microfluidic channel) and/or collected e.g., on fluidically isolated surfaces. For example, the single particle may be present in a plurality of particles of relatively high density and the single particle is flowed into a fluidic channel, such that it is separated from the plurality of particles. The particles may be spaced within a fluidic channel so that individual particles may be measured/observed over time. In certain embodiments, the particle may be a biological entity. Such article and methods may be useful, for example, for isolating single cells into individual wells of multi-well cell culture dishes (e.g., for single-cell analysis). |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 15/940001 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502746 (20130101) B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2300/0663 (20130101) B01L 2300/0864 (20130101) B01L 2400/0415 (20130101) B01L 2400/0487 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0205 (20130101) G01N 15/0255 (20130101) Original (OR) Class G01N 15/0618 (20130101) G01N 15/1056 (20130101) G01N 15/1484 (20130101) G01N 2015/149 (20130101) G01N 2015/0288 (20130101) G01N 2015/1006 (20130101) G01N 2015/1081 (20130101) G01N 2015/1087 (20130101) G01N 2015/1493 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162892 | Green |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | The USA, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Michael D. Green (Atlanta, Georgia) |
| ABSTRACT | A device (100) for measuring light transmission through a suspected counterfeit pharmaceutical tablet (102) includes a laser source (110) configured to emit a light transmission through the pharmaceutical tablet (102). A light detector (120) is included in the device (100) configured to receive the light transmission and measure an amount of light passed through the suspected counterfeit pharmaceutical tablet (102). The amount of light transmitted through the suspected counterfeit pharmaceutical tablet (102) is indicative of an authentic or counterfeit. |
| FILED | Friday, January 27, 2017 |
| APPL NO | 16/071843 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/63 (20130101) G01N 21/3563 (20130101) Original (OR) Class G01N 21/9508 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162900 | Paulsen et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire); UNIVERSITY HEALTH NETWORK (Toronto, Canada) |
| ASSIGNEE(S) | THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, New Hampshire); UNIVERSITY HEALTH NETWORK (Toronto, Canada) |
| INVENTOR(S) | Keith D. Paulsen (Hanover, New Hampshire); David W. Roberts (Lyme, New Hampshire); Dennis Wirth (Hanover, New Hampshire); Brian C. Wilson (Toronto, Canada); Mira Sibai (Toronto, Canada) |
| ABSTRACT | A method and device for determining the depth and fluorophore concentration of a fluorophore concentration below the surface of an optically absorbing and scattering medium suitable for use in fluorescence-based surgical guidance such as in tumor resection is described. Long-wavelength stimulus light us used to obtain deep tissue penetration. Recovery of depth is performed by fitting measured modulation amplitudes for each spatial frequency to precomputed modulation amplitudes in a table of modulation amplitudes indexed by optical parameters and depth. |
| FILED | Friday, April 26, 2019 |
| APPL NO | 17/050745 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measuring Length, Thickness or Similar Linear Dimensions; Measuring Angles; Measuring Areas; Measuring Irregularities of Surfaces or Contours G01B 11/22 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/4795 (20130101) G01N 21/6456 (20130101) Original (OR) Class G01N 33/4833 (20130101) G01N 2201/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162952 | Marcotte et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Edward Marcotte (Austin, Texas); Eric V. Anslyn (Austin, Texas); Andrew Ellington (Austin, Texas); Jagannath Swaminathan (Austin, Texas); Erik Hernandez (Austin, Texas); Amber Johnson (Austin, Texas); Alexander Boulgakov (Austin, Texas); James L. Bachman (Austin, Texas); Helen Seifert (Austin, Texas) |
| ABSTRACT | The disclosure concerns methods for identifying amino acids in peptides, including peptides including unnatural amino acids. Various aspects of the present disclosure provide compositions and methods for amino acid-type specific labeling, as well as methods for detecting the labels. Further disclosed herein are strategies for highly multiplexed, high-throughput peptide analysis. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/572194 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Peptides C07K 17/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/582 (20130101) G01N 33/6818 (20130101) G01N 33/6824 (20130101) Original (OR) Class G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162953 | Steyaert et al. |
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| FUNDED BY |
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| APPLICANT(S) | VIB VZW (Ghent, Belgium); Vrije Universiteit Brussel (Brussels, Belgium); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | VIB VZW (Ghent, Belgium); Vrije Universiteit Brussel (Brussels, Belgium); Board of Trustees of Leland Stanford Jr University (Palo Alto, California) |
| INVENTOR(S) | Jan Steyaert (Beersel, Belgium); Els Pardon (Wezemaal, Belgium); Soren G. F. Rasmussen (Frederiksberg, Denmark); Juan Jose Fung (San Jose, California); Brian Kobilka (Palo Alto, California); Toon Laeremans (Dworp, Belgium) |
| ABSTRACT | The present invention relates to the field of GPCR structure biology and signaling. In particular, the present invention relates to protein binding domains directed against or capable of specifically binding to a functional conformational state of a G-protein-coupled receptor (GPCR). More specifically, the present invention provides protein binding domains that are capable of increasing the stability of a functional conformational state of a GPCR, in particular, increasing the stability of a GPCR in its active conformational state. The protein binding domains of the present invention can be used as a tool for the structural and functional characterization of G-protein-coupled receptors bound to various natural and synthetic ligands, as well as for screening and drug discovery efforts targeting GPCRs. Moreover, the invention also encompasses the diagnostic, prognostic and therapeutic usefulness of these protein binding domains for GPCR-related diseases. |
| FILED | Tuesday, July 30, 2019 |
| APPL NO | 16/526099 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) C07K 14/723 (20130101) C07K 16/28 (20130101) C07K 2317/22 (20130101) C07K 2317/33 (20130101) C07K 2317/51 (20130101) C07K 2317/56 (20130101) C07K 2317/75 (20130101) C07K 2317/569 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20 (20130101) G01N 33/68 (20130101) G01N 33/566 (20130101) G01N 33/6857 (20130101) G01N 33/6872 (20130101) Original (OR) Class G01N 2333/726 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162954 | Steyaert et al. |
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| FUNDED BY |
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| APPLICANT(S) | VIB VZW (Ghent, Belgium); Vrije Universiteit Brussel (Brussels, Belgium); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, California) |
| ASSIGNEE(S) | VIB VZW (Ghent, Belgium); Vrije Universiteit Brussel (Brussels, Belgium); Board of Trustees Leland Stanford Jr University (Palo Alto, California) |
| INVENTOR(S) | Jan Steyaert (Beersel, Belgium); Els Pardon (Wezemaal, Belgium); Soren G. F. Rasmussen (Frederiksberg, Denmark); Juan Jose Fung (San Jose, California); Brian Kobilka (Palo Alto, California); Toon Laeremans (Dworp, Belgium) |
| ABSTRACT | The present invention relates to the field of GPCR structure biology and signaling. In particular, the present invention relates to protein binding domains directed against or capable of specifically binding to a functional conformational state of a G-protein-coupled receptor (GPCR). More specifically, the present invention provides protein binding domains that are capable of increasing the stability of a functional conformational state of a GPCR, in particular, increasing the stability of a GPCR in its active conformational state. The protein binding domains of the present invention can be used as a tool for the structural and functional characterization of G-protein-coupled receptors bound to various natural and synthetic ligands, as well as for screening and drug discovery efforts targeting GPCRs. Moreover, the invention also encompasses the diagnostic, prognostic and therapeutic usefulness of these protein binding domains for GPCR-related diseases. |
| FILED | Tuesday, July 30, 2019 |
| APPL NO | 16/526129 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) C07K 14/723 (20130101) C07K 16/28 (20130101) C07K 2317/22 (20130101) C07K 2317/33 (20130101) C07K 2317/51 (20130101) C07K 2317/56 (20130101) C07K 2317/75 (20130101) C07K 2317/569 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 23/20 (20130101) G01N 33/68 (20130101) G01N 33/566 (20130101) G01N 33/6857 (20130101) G01N 33/6872 (20130101) Original (OR) Class G01N 2333/726 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162960 | Xiao et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yi Xiao (Miami, Florida); Haixiang Yu (Miami, Florida); Juan Canoura (Hialeah Gardens, Florida); Yingzhu Liu (Miami, Florida) |
| ASSIGNEE(S) | THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami, Florida) |
| INVENTOR(S) | Yi Xiao (Miami, Florida); Haixiang Yu (Miami, Florida); Juan Canoura (Hialeah Gardens, Florida); Yingzhu Liu (Miami, Florida) |
| ABSTRACT | The subject invention provides methods, assays, and products for detecting small-molecule targets in a complex sample in both clinical and field settings. The subject invention provides aptamer-based sensors and methods of use thereof. The subject invention provides exonuclease-based methods for generating structure-switching aptamers from fully folded or pre-folded aptamers and developing aptamer-based sensors for small-molecule detection. The method for detecting one or more small-molecule targets in a sample comprises contacting the sample with one or more aptamer-based sensor selective for each of the small-molecule targets, and detecting the small-molecule target in the sample. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 16/437021 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/115 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) Enzymes C12Y 301/15 (20130101) C12Y 301/16 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/946 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163028 | Alsop et al. |
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| FUNDED BY |
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| APPLICANT(S) | Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts) |
| INVENTOR(S) | David C. Alsop (Newton, Massachusetts); Li Zhao (Boston, Massachusetts) |
| ABSTRACT | Systems and methods for acquiring magnetic resonance imaging (MRI) images of a subject are provided. The method includes performing a pulse sequence to elicit spin echoes, wherein the pulse sequence includes a radio frequency (RF) excitation pulse and a series of RF refocusing pulses that refocus echoes with flip angles in the series of RF refocusing pulses that are varied. The method also includes scaling MRI data associated with each echo by a correction factor that is determined for each echo to create scaled MRI data and that is not the same for all echoes. The method then includes reconstructing an image of the subject using the scaled MRI data. |
| FILED | Thursday, March 22, 2018 |
| APPL NO | 16/498672 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5602 (20130101) G01R 33/5617 (20130101) Original (OR) Class Electric Digital Data Processing G06F 7/22 (20130101) G06F 30/20 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11164021 | Rahman Siddiquee et al. |
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| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Md Mahfuzur Rahman Siddiquee (Tempe, Arizona); Zongwei Zhou (Tempe, Arizona); Ruibin Feng (Tempe, Arizona); Nima Tajbakhsh (Los Angeles, California); Jianming Liang (Scottsdale, Arizona) |
| ABSTRACT | Methods, systems, and media for discriminating and generating translated images are provided. In some embodiments, the method comprises: identifying a set of training images, wherein each image is associated with at least one domain from a plurality of domains; training a generator network to generate: i) a first fake image that is associated with a first domain; and ii) a second fake image that is associated with a second domain; training a discriminator network, using as inputs to the discriminator network: i) an image from the set of training images; ii) the first fake image; and iii) the second fake image; and using the generator network to generate, for an image not included in the set of training images at least one of: i) a third fake image that is associated with the first domain; and ii) a fourth fake image that is associated with the second domain. |
| FILED | Friday, May 15, 2020 |
| APPL NO | 16/875680 |
| ART UNIT | 2645 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00362 (20130101) G06K 9/00899 (20130101) Original (OR) Class G06K 9/6256 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11164312 | Saltz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for the State University of New York (Albany, New York); Board of Regents, The University of Texas System (Austin, Texas); Emory University (Atlanta, Georgia); Institute for Systems Biology (Seattle, Washington) |
| ASSIGNEE(S) | The Research Foundation tor the State University of New York (Albany, New York); Board of Regents, The University of Texas System (Austin, Texas); Institute for Systems Biology (Seattle, Washington) |
| INVENTOR(S) | Joel Haskin Saltz (Manhasset, New York); Tahsin Kurc (Coram, New York); Rajarsi Gupta (Flushing, New York); Tianhao Zhao (Coram, New York); Rebecca Batiste (Stony Brook, New York); Le Hou (Stony Brook, New York); Vu Nguyen (Stony Brook, New York); Dimitrios Samaras (Rocky Point, New York); Arvind Rao (Houston, Texas); John Van Arnam (Houston, Texas); Pankaj Singh (Houston, Texas); Alexander Lazar (Houston, Texas); Ashish Sharma (Atlanta, Georgia); Ilya Shmulevich (Seattle, Washington); Vesteinn Thorsson (Seattle, Washington) |
| ABSTRACT | A system associated with quantifying a density level of tumor-infiltrating lymphocytes, based on prediction of reconstructed TIL information associated with tumoral tissue image data during pathology analysis of the tissue image data is disclosed. The system receives digitized diagnostic and stained whole-slide image data related to tissue of a particular type of tumoral data. Defined are regions of interest that represents a portion of, or a full image of the whole-slide image data. The image data is encoded into segmented data portions based on convolutional autoencoding of objects associated with the collection of image data. The density of tumor-infiltrating lymphocytes is determined of bounded segmented data portions for respective classification of the regions of interest. A classification label is assigned to the regions of interest. It is determined whether an assigned classification label is above a pre-determined threshold probability value of lymphocyte infiltrated. The threshold probability value is adjusted in order to re-assign the classification label to the regions of interest based on a varied sensitivity level of density of lymphocyte infiltrated. A trained classification model is generated based on the re-assigned classification labels to the regions of interest associated with segmented data portions using the adjusted threshold probability value. An unlabeled image data set is received to iteratively classify the segmented data portions based on a lymphocyte density level associated with portions of the unlabeled image data set, using the trained classification model. Tumor-infiltrating lymphocyte representations are generated based on prediction of TIL information associated with classified segmented data portions. A refined TIL representation based on prediction of the TIL representations is generated using the adjusted threshold probability value associated with the classified segmented data portions. A corresponding method and computer-readable device are also disclosed. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/762326 |
| ART UNIT | 2663 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/3233 (20130101) G06K 9/6256 (20130101) G06K 9/6267 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) G06T 7/0012 (20130101) Original (OR) Class G06T 9/00 (20130101) G06T 2207/20076 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11160498 | Wernke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Matthew Michael Wernke (Columbus, Ohio); Samuel Lon Phillips (Seminole, Florida); Derek James Lura (Tampa, Florida); Stephanie Lutton Carey (Tampa, Florida); Rajiv V. Dubey (Tampa, Florida) |
| ABSTRACT | A device and method for measuring prosthetic or orthotic slip is presented. An optical sensor device is attached to the prosthesis or orthosis and measures the amount of relative motion between the prosthetic socket and the residual limb surface or between the orthosis and the affected body part. The sensor device is comprised of an optical sensor, a light source, a processing unit and a power source contained within a housing. A system for measuring multidirectional prosthetic or orthotic slip using the sensor device and automatically adjusting the fit of the prosthetic based on a determined threshold is also presented. |
| FILED | Wednesday, December 20, 2017 |
| APPL NO | 15/848233 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4851 (20130101) Original (OR) Class Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/70 (20130101) A61F 2/76 (20130101) A61F 2/80 (20130101) A61F 5/01 (20130101) A61F 5/0118 (20130101) A61F 2002/704 (20130101) A61F 2002/802 (20130101) A61F 2002/5036 (20130101) A61F 2002/6881 (20130101) A61F 2002/7615 (20130101) A61F 2002/7695 (20130101) A61F 2005/0188 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160576 | Emery et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as Represented by the Secretary of the Navy (Indian Head, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Samuel Emery (Alexandria, Virginia); Lee Foltz (Indian Head, Maryland); Daniel McCarthy (LaPlata, Maryland); Keith Chamberlain (Waldorf, Maryland); Kerry Clark (LaPlata, Maryland); Peter A. Margiotta (LaPlata, Maryland); Matthew Bradley (Columbia, Maryland); David R. Whittaker (Potomac, Maryland); Erin E. Koelling (Washington, District of Columbia) |
| ABSTRACT | An amputation system includes a cutting element having a cutting blade traversing a V-shape. The V-shape has a vertex and an angle in a range of 90-120°. A rod, rigidly coupled to the cutting element, has its longitudinal axis aligned with the vertex so it bisects the angle of the V-shape. A barrel having a bore receives at least a portion of the rod therein wherein the rod's outboard end resides in the bore. An energetic energy source, positioned in the bore adjacent to the rod's outboard end, generates a pressure force that is incident on the rod's outboard end. The pressure force is one that peaks within 0.5 milliseconds to propel the rod from the bore at a velocity in a range of 300 to 1000 feet per second. |
| FILED | Monday, June 29, 2020 |
| APPL NO | 16/873765 |
| ART UNIT | 3775 — Medical & Surgical Instruments, Treatment Devices, Surgery and Surgical Supplies |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/17 (20130101) A61B 17/32 (20130101) Original (OR) Class A61B 17/1628 (20130101) A61B 2017/00477 (20130101) A61B 2017/320052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160853 | Disis et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington through its Center for Commercialization (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATON (Seattle, Washington) |
| INVENTOR(S) | Mary L. Disis (Renton, Washington); Denise Cecil (Shoreline, Washington); Meredith Slota (Seattle, Washington) |
| ABSTRACT | The compositions described herein include an epitope of a peptide that may elicit an immune response in a subject following administration. The compositions may comprise nucleic acids. The compositions may comprise peptides. The methods described herein include administering a composition comprising an epitope of a peptide to a subject in need thereof. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 16/370683 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/00115 (20180801) A61K 39/001103 (20180801) A61K 39/001106 (20180801) A61K 39/001129 (20180801) A61K 39/001152 (20180801) A61K 48/00 (20130101) A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/572 (20130101) Peptides C07K 14/71 (20130101) C07K 14/705 (20130101) C07K 14/4702 (20130101) C07K 14/70567 (20130101) C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/104 (20130101) Enzymes C12Y 203/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161214 | Thompson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steven Thompson (Callaway, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Steven Thompson (Callaway, Maryland) |
| ABSTRACT | A sharpener cover retrofit attachment to retrofit an electrode sharpener cover attachment on an electrode sharpener, the electrode sharpener for sharpening an electrode rod and having a protruding hollow sharpener shaft with a sharpener shaft outer diameter and a rotating sharpener shaft inner diameter for accepting the electrode rod. The attachment includes a first and second annulus, both axially aligned such that they are able to accept and align the electrode rod into the rotating sharpener shaft inner diameter. |
| FILED | Friday, February 01, 2019 |
| APPL NO | 16/265209 |
| ART UNIT | 3723 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Machines, Devices, or Processes for Grinding or Polishing; Dressing or Conditioning of Abrading Surfaces; Feeding of Grinding, Polishing, or Lapping Agents B24B 3/60 (20130101) B24B 5/22 (20130101) B24B 5/307 (20130101) Original (OR) Class B24B 19/16 (20130101) B24B 41/06 (20130101) B24B 41/066 (20130101) Tools for Grinding, Buffing, or Sharpening B24D 15/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161744 | Tour et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas); BEN-GURION UNIVERSITY (Beer Sheva, Israel) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas); B.G. Negev Technologies and Applications, Ltd., at Ben-Gurion University (Beer Sheva, Israel) |
| INVENTOR(S) | James M. Tour (Bellaire, Texas); Yieu Chyan (Houston, Texas); Christopher John Arnusch (Midreshet Ben-Gurion, Israel); Swatantra Pratap Singh (Midreshet Ben-Gurion, Israel); Yilun Li (Sugar Land, Texas); Duy X. Luong (Houston, Texas); Carter Kittrell (Houston, Texas); Ruquan Ye (Houston, Texas); Jordan Miller (Houston, Texas); Ian Kinstlinger (Houston, Texas); Savannah Cofer (Gahanna, Ohio) |
| ABSTRACT | Methods that expand the properties of laser-induced graphene (LIG) and the resulting LIG having the expanded properties. Methods of fabricating laser-induced graphene from materials, which range from natural, renewable precursors (such as cloth or paper) to high performance polymers (like Kevlar). With multiple lasing, however, highly conductive PEI-based LIG could be obtained using both multiple pass and defocus methods. The resulting laser-induced graphene can be used, inter alia, in electronic devices, as antifouling surfaces, in water treatment technology, in membranes, and in electronics on paper and food Such methods include fabrication of LIG in controlled atmospheres, such that, for example, superhydrophobic and superhydrophilic LIG surfaces can be obtained. Such methods further include fabricating laser-induced graphene by multiple lasing of carbon precursors. Such methods further include direct 3D printing of graphene materials from carbon precursors. Application of such LIG include oil/water separation, liquid or gas separations using polymer membranes, anti-icing, microsupercapacitors, supercapacitors, water splitting catalysts, sensors, and flexible electronics. |
| FILED | Monday, November 06, 2017 |
| APPL NO | 16/347451 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/01 (20130101) C01P 2002/82 (20130101) C01P 2004/03 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/005 (20130101) H01S 3/0007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161961 | Channu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Avomeen Analytical Services (Ann Arbor, Michigan) |
| ASSIGNEE(S) | Avomeen Analytical Services (Ann Arbor, Michigan) |
| INVENTOR(S) | Venkata S. Reddy Channu (Ann Arbor, Michigan); Shri Thanedar (Ann Arbor, Michigan) |
| ABSTRACT | The present invention provides a novel process that involves a reliable, robust, reproducible, and cost effective casting technique for a shutdown separator with, for example, a combination of poly(vinylidene fluoride-co-hexafluoropropylene) (PVdF-HFP) copolymer, polysulfonamide (PSA)/polyether imide (PEI), and CaCO3 powder, and for a non-shutdown separator with, for example, a combination of polysulfonamide (PSA)/polyether imide (PEI), filler/plasticizer, and metal oxide nanostructures (SiO2, TiO2, and Al2O3). |
| FILED | Friday, April 21, 2017 |
| APPL NO | 15/493534 |
| ART UNIT | 1724 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/013 (20180101) Original (OR) Class C08K 3/013 (20180101) C08K 3/22 (20130101) Compositions of Macromolecular Compounds C08L 25/06 (20130101) C08L 27/06 (20130101) C08L 27/16 (20130101) C08L 27/16 (20130101) C08L 71/00 (20130101) C08L 79/00 (20130101) C08L 81/10 (20130101) C08L 81/10 (20130101) C08L 81/10 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 50/446 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161987 | Detty et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Amherst, New York) |
| INVENTOR(S) | Michael Detty (Rochester, New York); Damon Corey (Amherst, New York); Caitlyn Gatley (Cheektowaga, New York) |
| ABSTRACT | Xerogels and compositions comprising xerogels comprising a transition metal oxide and silicon oxide xerogel matrix. The xerogels and compositions can be made from mixtures of transition metal alkoxide(s) and tetraalkoxysilane(s) and, optionally, alkyltrialkoxysilane(s), aminoalkyl-, alkylaminoalkyl-, dialkylaminoalkyltrialkoxysilane(s), or a combination thereof. The xerogels and compositions can be used as antifouling coatings on, for example; boats. |
| FILED | Friday, December 09, 2016 |
| APPL NO | 16/060566 |
| ART UNIT | 1765 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Non-metallic Elements; Compounds Thereof; C01B 33/16 (20130101) C01B 33/163 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 77/58 (20130101) C08G 83/001 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 1/00 (20130101) C09D 5/1618 (20130101) C09D 5/1625 (20130101) C09D 5/1656 (20130101) C09D 5/1675 (20130101) Original (OR) Class C09D 5/1681 (20130101) C09D 7/63 (20180101) C09D 183/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162000 | Wynne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| ASSIGNEE(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| INVENTOR(S) | Kenneth J. Wynne (Midlothian, Virginia); Wei Zhang (Midlothian, Virginia) |
| ABSTRACT | A compound is provided, having the formula (I), wherein RS is a soft block polymer; wherein each T is independently a urethane or urea linkage; see formulae (A) and (B); wherein each RD is independently —CH3, —CH2CH3, —CH2CH2CH3, or —CH2CH2CH2CH3; wherein each R′D is independently —CH3, —CH2CH3, —CH2CH2CH3, —CH2CH2CH2CH3, or —ORD; and wherein each p is independently 1, 2, or 3. Compositions containing the compound, and methods of making and using the compound are provided. |
| FILED | Monday, November 12, 2018 |
| APPL NO | 16/188192 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/336 (20130101) C08G 77/54 (20130101) C08G 77/388 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/5465 (20130101) C08K 5/5465 (20130101) C08K 5/5465 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) C08L 75/04 (20130101) C08L 83/04 (20130101) C08L 83/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 171/02 (20130101) Original (OR) Class C09D 183/14 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162128 | Glaros et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Edgewood Chemical Biological Center (Apg, Maryland) |
| ASSIGNEE(S) | The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Trevor G Glaros (North East, Maryland); Elizabeth S Dhummakupt (Abingdon, Maryland); Phillip M. Mach (Edgewood, Maryland); Daniel O Carmany (Belcamp, Maryland) |
| ABSTRACT | An apparatus and method for detecting an analyte of interest using paper spray mass spectrometry includes a spray material; a sample on the spray material including an enzyme of interest; a solvent to hydrate the sample, promote enzymatic activity, and extract analytes of interest from the sample; a substrate specific to the enzyme of interest, wherein any of the spray material and the solvent includes the substrate; a voltage source to apply a voltage to the spray material to create charged droplets of a mixture containing the sample; and a mass spectrometer to perform spectrometry on the droplets to perform any of: identify the analytes of interest in the sample; and measure a level of inhibition in any enzymes contained in the sample. |
| FILED | Thursday, May 10, 2018 |
| APPL NO | 15/976120 |
| ART UNIT | 1651 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/46 (20130101) Original (OR) Class Enzymes C12Y 301/01007 (20130101) C12Y 301/01008 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6848 (20130101) G01N 2560/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/168 (20130101) H01J 49/0445 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162147 | Chen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shengxi Chen (Chandler, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Shengxi Chen (Chandler, Arizona) |
| ABSTRACT | The present disclosure provides a low cost, high sensitivity, high specificity and rapid diagnostic apparatus and method to detect nucleic acids in a sample at room temperature. As low as tens of copies of nucleic acids can be detected without any additional equipment. |
| FILED | Tuesday, June 04, 2019 |
| APPL NO | 16/431678 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162179 | Ren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF HOUSTON SYSTEM (Houston, Texas) |
| INVENTOR(S) | Zhifeng Ren (Pearland, Texas); Haiqing Zhou (Houston, Texas); Fang Yu (Houston, Texas); Shuo Chen (Houston, Texas) |
| ABSTRACT | A hybrid three dimensional (3D) hydrogen evolution reaction (HER) catalyst that is formed from a porous Ni foam support, a NiSe2 scaffold positioned on the support; and layered transition metal dichalcogenide (LTMDC) or first-row transition metal dichalcogenide particles positioned on the NiSe2 scaffold. The catalyst provides a low onset potential, large cathode current density, small Tafel slopes, and large exchange current densities, similar in catalytic power to Pt HER catalysts. |
| FILED | Wednesday, May 17, 2017 |
| APPL NO | 16/302572 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 11/031 (20210101) C25B 11/051 (20210101) C25B 11/057 (20210101) C25B 11/075 (20210101) C25B 11/091 (20210101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/90 (20130101) H01M 4/8605 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162192 | Gopinath et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Ashwin Gopinath (Pasadena, California); Paul Rothemund (Pasadena, California); Rishabh Shetty (Tempe, Arizona); Rizal Hariadi (Phoenix, Arizona) |
| ABSTRACT | Embodiments of the present disclosure relate generally to single molecule arrays. More particularly, the present disclosure provides materials and methods for generating single molecule arrays using bottom-up self-assembly processes. Materials and methods of the present disclosure can be used to generate single molecule arrays with nanoapertures (e.g., zero mode waveguides) and for carrying out rapid, point-of-care biomolecule detection and quantification. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/762024 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/00497 (20130101) B01J 2219/00596 (20130101) B01J 2219/00612 (20130101) B01J 2219/00722 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162212 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Zheng Wang (Burke, Virginia); Brandy J. White (Washington, District of Columbia); Gaurav J. Vora (Washington, District of Columbia); Martin H. Moore (Woodbridge, Virginia) |
| ABSTRACT | The application of melanin to fabric improves resistance to chemical pass-through, with possible application in protective garments, shelters, and filtration materials. |
| FILED | Wednesday, June 19, 2019 |
| APPL NO | 16/445842 |
| ART UNIT | 1761 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/10 (20130101) Treatment, Not Provided for Elsewhere in Class D06, of Fibres, Threads, Yarns, Fabrics, Feathers or Fibrous Goods Made From Such Materials D06M 10/003 (20130101) D06M 10/08 (20130101) D06M 13/52 (20130101) D06M 13/352 (20130101) Original (OR) Class D06M 13/513 (20130101) D06M 2400/01 (20130101) Dyeing or Printing Textiles; Dyeing Leather, Furs or Solid Macromolecular Substances in Any Form D06P 1/34 (20130101) D06P 1/44 (20130101) D06P 1/0052 (20130101) D06P 5/002 (20130101) D06P 5/22 (20130101) D06P 5/2072 (20130101) D06P 5/2083 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162737 | Retersdorf |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| INVENTOR(S) | Alan Retersdorf (Avon, Connecticut) |
| ABSTRACT | A cold layer adapted for use in a cross counter flow heat exchanger core includes a hot inlet tent for receiving hot flow and a hot outlet tent for discharging hot flow. The cold layer is configured to receive a cold inlet flow and discharge a cold outlet flow defining a main cold flow direction. The cold layer includes a first and second cold main closure bar, each parallel to the main cold flow direction and located near the respective hot inlet or outlet tent, cold main fins perpendicular to the direction of the hot inlet flow, and cold inlet corner fins near the hot inlet tent, configured to receive a portion of the cold inlet flow in a direction that forms an angle with the main cold flow that is greater than 5 degrees. |
| FILED | Monday, April 29, 2019 |
| APPL NO | 16/397788 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 9/0031 (20130101) Original (OR) Class F28D 9/0068 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 3/025 (20130101) F28F 3/046 (20130101) F28F 2250/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162841 | Han et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | SAMSUNG ELECTRONICS CO., LTD. (Suwon-si, South Korea); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Seunghoon Han (Seoul, South Korea); Amir Arbabi (Pasadena, California); Andrei Faraon (Pasadena, California); Ehsan Arbabi (Pasadena, California) |
| ABSTRACT | A spectrometer includes a substrate; a slit which is provided on the substrate and through which light is incident onto the substrate; a metasurface including nanostructures that is configured to reflect and focus the light incident thereon through the slit, at different angles based on respective wavelengths; and a sensor which is provided on one side of the substrate that is opposite to another side of the substrate at which the metasurface is disposed, and configured to receive the light from the metasurface. |
| FILED | Friday, November 22, 2019 |
| APPL NO | 16/692776 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/0205 (20130101) G01J 3/0208 (20130101) Original (OR) Class G01J 3/0224 (20130101) G01J 3/0256 (20130101) G01J 3/0259 (20130101) G01J 3/447 (20130101) G01J 3/2803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162952 | Marcotte et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Edward Marcotte (Austin, Texas); Eric V. Anslyn (Austin, Texas); Andrew Ellington (Austin, Texas); Jagannath Swaminathan (Austin, Texas); Erik Hernandez (Austin, Texas); Amber Johnson (Austin, Texas); Alexander Boulgakov (Austin, Texas); James L. Bachman (Austin, Texas); Helen Seifert (Austin, Texas) |
| ABSTRACT | The disclosure concerns methods for identifying amino acids in peptides, including peptides including unnatural amino acids. Various aspects of the present disclosure provide compositions and methods for amino acid-type specific labeling, as well as methods for detecting the labels. Further disclosed herein are strategies for highly multiplexed, high-throughput peptide analysis. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/572194 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Peptides C07K 17/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/58 (20130101) G01N 33/582 (20130101) G01N 33/6818 (20130101) G01N 33/6824 (20130101) Original (OR) Class G01N 2570/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163060 | Pushee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Kevin A Pushee (Jamestown, Rhode Island); Patric K Lockhart (Richmond, Rhode Island) |
| ABSTRACT | A method for increasing localization utilizing overlapped broadband pulses includes using a transform to convert broadband returns into wavelength based returns. The wavelength based returns are grouped into at least two wavelength group returns for each location having different focal diameters. Intra-return probabilities of object location are computed from the group returns. Inter-return probabilities are computed for overlapping regions of the pulse returns. A pixel grid is established for displaying the calculated object location probabilities. By further processing, the pixel grid can be refined to show finer details. |
| FILED | Tuesday, March 12, 2019 |
| APPL NO | 16/299201 |
| ART UNIT | 3648 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 13/9005 (20130101) Original (OR) Class G01S 13/9011 (20130101) G01S 17/89 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163116 | Lopez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Josue Lopez (South Gate, California); Samuel Kim (Cambridge, Massachusetts); Jamison Sloan (Somerville, Massachusetts); Boris Kharas (Lexington, Massachusetts); Jeffrey Scott Herd (Rowley, Massachusetts); Marin Soljacic (Belmont, Massachusetts); Cheryl Marie Sorace-Agaskar (Bedford, Massachusetts); Suraj Deepak Bramhavar (Arlington, Massachusetts); Steven Glenn Johnson (Arlington, Massachusetts); George Barbastathis (Boston, Massachusetts) |
| ABSTRACT | An integrated optical beam steering device includes a planar Luneburg lens that collimates beams from different inputs in different directions within the lens plane. It also includes a curved (e.g., semi-circular or arced) grating coupler that diffracts the collimated beams out of the lens plane. The beams can be steered in the plane by controlling the direction along which the lens is illuminated and out of the plane by varying the beam wavelength. Unlike other beam steering devices, this device can operate over an extremely wide field of view—up to 180°—without any aberrations off boresight. In other words, the beam quality is uniform in all directions, unlike with aplanatic lenses, thanks to the circular symmetry of the planar Luneburg lens, which may be composed of subwavelength features. The lens is also robust to misalignment and fabrication imperfections and can be made using standard CMOS processes. |
| FILED | Friday, February 28, 2020 |
| APPL NO | 16/804612 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/124 (20130101) Original (OR) Class G02B 6/125 (20130101) G02B 6/12004 (20130101) G02B 2006/12102 (20130101) G02B 2006/12107 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/2955 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163124 | Veitch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wavefront Research, Inc. (Northampton, Pennsylvania) |
| ASSIGNEE(S) | Wavefront Research, Inc. (Northhampton, Pennsylvania) |
| INVENTOR(S) | Randall C. Veitch (Nazareth, Pennsylvania); Thomas W. Stone (Hellertown, Pennsylvania) |
| ABSTRACT | Compact ASIC, chip-on-board, flip-chip, interposer, and related packaging techniques are incorporated to minimize the footprint of optoelectronic interconnect devices, including the Optical Data Pipe. In addition, ruggedized packaging techniques are incorporated to increase the durability and application space for optoelectronic interconnect devices, including an Optical Data Pipe. |
| FILED | Monday, September 14, 2020 |
| APPL NO | 17/020358 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4204 (20130101) G02B 6/4212 (20130101) Original (OR) Class G02B 6/4239 (20130101) G02B 6/4244 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02327 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/181 (20130101) H05K 1/0274 (20130101) H05K 3/284 (20130101) H05K 2201/10121 (20130101) H05K 2201/10128 (20130101) H05K 2201/10143 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) Technical Subjects Covered by Former US Classification Y10T 29/49002 (20150115) Y10T 29/49117 (20150115) Y10T 29/49144 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163152 | Starman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | LaVern A Starman (Dayton, Ohio); John P K Walton (Troy, Ohio); David Torres Reyes (Springboro, Ohio) |
| ABSTRACT | An actuator element of a MEMS device on a substrate is provided to create large, out-of-plane deflection. The actuator element includes a metallic layer having a first portion contacting the substrate and a second portion having an end proximal to the first portion. A distal end is cantilevered over the substrate. A first insulating layer contacts the metallic layer on a bottom contacting surface of the second cantilevered portion from the proximal to the distal end. A second insulating layer contacts the metallic layer on a portion of a top contacting surface at the distal end. The second portion of the metallic layer is prestressed. A coefficient of thermal expansion of the first and second insulating layers is different than a coefficient of thermal expansion of the metallic layer. And, a Young's modulus of the first and second insulating layer is different than a Young's modulus of the metallic layer. |
| FILED | Friday, November 01, 2019 |
| APPL NO | 16/671736 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0043 (20130101) B81B 2201/032 (20130101) B81B 2201/042 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/0038 (20130101) Optical Elements, Systems, or Apparatus G02B 26/0866 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163168 | Leger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | James Robert Leger (Minneapolis, Minnesota); William Minster Kunkel (Minneapolis, Minnesota); Di Lin (Minneapolis, Minnesota) |
| ABSTRACT | Methods, systems, and apparatus, including computer programs encoded on a computer storage medium for managing beam shaping in gradient refractive index (GRIN) media are provided. In one aspect, a method includes specifying a field evolution throughout a gradient-index (GRIN) medium and generating a refractive index profile of the GRIN medium based on the specified field evolution in the GRIN medium. Diffraction effects are considered in solving for the refractive index profile. The index profile is found by specifying a desired beam transformation throughout the GRIN medium and solving a series of phase retrieval problems. The GRIN medium can be two-dimensional (2D) or three-dimensional (3D). |
| FILED | Friday, June 08, 2018 |
| APPL NO | 16/003315 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 3/0087 (20130101) G02B 19/0004 (20130101) G02B 19/0047 (20130101) G02B 19/0052 (20130101) G02B 27/0012 (20130101) G02B 27/0927 (20130101) G02B 27/0955 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163206 | Manzur et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Tariq Manzur (Lincoln, Rhode Island); Yifei Li (East Walpole, Massachusetts) |
| ABSTRACT | An active optical modulator receives a radio frequency signal and provides an intensity modulated optical signal. The optical modulator is formed on a substrate having a doped region. An interferometer is formed on the substrate having a first path and a second path. A low noise amplifier receives the radio frequency signal and provides an electrical field to the paths. A signal laser provides an optical signal to the interferometer which is modulated and interfered to produce an intensity modulated optical signal. A pump laser provides an optical gain signal to the interferometer where it adds gain to the optical signal in the interferometer by interaction with the doped region of the substrate. |
| FILED | Thursday, July 02, 2020 |
| APPL NO | 16/919237 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/212 (20210101) G02F 1/2255 (20130101) Original (OR) Class Amplifiers H03F 3/195 (20130101) H03F 2200/294 (20130101) Transmission H04B 10/505 (20130101) H04B 10/5051 (20130101) H04B 10/5055 (20130101) H04B 2210/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163207 | Frantz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Jesse A. Frantz (Washington, District of Columbia); Jason D. Myers (Alexandria, Virginia); Robel Y. Bekele (Washington, District of Columbia); Christopher M. Spillmann (Annandale, Virginia); Jawad Naciri (Herndon, Virginia); Jakub Kolacz (Washington, District of Columbia); Henry G. Gotjen (Washington, District of Columbia); Jason Auxier (Falls Church, Virginia); Leslie Brandon Shaw (Woodbridge, Virginia); Jasbinder S. Sanghera (Ashburn, Virginia) |
| ABSTRACT | A liquid crystal-based non-mechanical beam steering device that permits steering in the mid-wave infrared and has a chalcogenide waveguide. The waveguide core, the subcladding, or both comprise a chalcogenide glass. The liquid crystal-based non-mechanical beam steering device has a tapered subcladding and a liquid crystal layer. |
| FILED | Friday, May 22, 2020 |
| APPL NO | 16/881225 |
| ART UNIT | 2871 — Optics |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/321 (20130101) C03C 13/043 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/011 (20130101) G02F 1/0018 (20130101) G02F 1/0113 (20210101) G02F 1/292 (20130101) Original (OR) Class G02F 1/1326 (20130101) G02F 1/1337 (20130101) G02F 1/2955 (20130101) G02F 1/134309 (20130101) G02F 2203/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163804 | Beller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles E. Beller (Baltimore, Maryland); William G. Dubyak (Severna Park, Maryland); Palani Sakthi (Palantine, Illinois); Kristen M. Summers (Takoma Park, Maryland) |
| ABSTRACT | Embodiments can provide a computer implemented method, in a data processing system comprising a processor and a memory comprising instructions which are executed by the processor to cause the processor to implement an enhanced corpus management system, the method comprising: identifying one or more functional domain categories; ingesting one or more incoming documents to form an open-domain corpus; for each functional domain category, identifying one or more representative documents to establish a seed sub-corpus; calculating a degree of fit score between each of the one or more incoming documents and the one or more established functional domain category seed sub-corpora; and assigning one or more of the incoming documents to one or more of the functional domain categories based upon the degree of fit score to create an enhanced corpus. |
| FILED | Friday, May 03, 2019 |
| APPL NO | 16/402692 |
| ART UNIT | 2163 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 7/08 (20130101) G06F 16/248 (20190101) G06F 16/285 (20190101) Original (OR) Class G06F 16/2228 (20190101) G06F 16/2455 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163890 | Price et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (San Diego, California) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Michael Allen Price (Levittown, Pennsylvania); Ryan Scott Elder (Washington Crossing, Pennsylvania); Warren Fuchs Brodsky (Lansdale, Pennsylvania); James Hart Allphin (San Diego, California) |
| ABSTRACT | A self-targeting method of automated cybersecurity analysis on an operating system on a target computer. An analysis software executable defined by a core engine executable is provided to the target computer and run on the operating system shell. The analysis software executable identifies the specific operating system that is running on the target computer and then causes one or a plurality of bash scripts which correspond to the identified operating system and which have been parsed from security setting entries from a standardized guide for desired security settings. The bash scripts then automatically assess the compliance of various aspects of the target computer system with the security setting entries, generating an output that is compatible with existing viewers for entries of standardized guides. |
| FILED | Wednesday, October 09, 2019 |
| APPL NO | 16/597227 |
| ART UNIT | 2436 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 21/577 (20130101) Original (OR) Class G06F 2221/033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163906 | Zakour |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Orbis Technologies, Inc. (Annapolis, Maryland) |
| ASSIGNEE(S) | Orbis Technologies, Inc. (Annapolis, Maryland) |
| INVENTOR(S) | Elias Zakour (Severna Park, Maryland) |
| ABSTRACT | Methods, systems and computer program products are provided to automate redaction of data and metadata. Without modification of the underlying source code, a user may modify, add or remove rules and/or templates for governing redaction of data and metadata of source artifacts. Additionally, the system may automatically infer relationships between modified metadata parameters from application updates and normalized metadata parameters. In some cases, the system may add metadata to the redacted work products for compliance or other purposes. Additionally, redacted work products may comprise redacted source artifacts and a list of rules and/or templates applied to the source artifacts during redaction. |
| FILED | Thursday, October 04, 2018 |
| APPL NO | 16/151694 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/22 (20190101) G06F 21/6254 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11164036 | Irving et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Samuel Irving (Baton Rouge, Louisiana); Christopher J. Michael (Mandeville, Louisiana); Meg Palmsten (Pass Christian, Mississippi); Steven Dennis (Covington, Louisiana) |
| ABSTRACT | Systems and methods are provided for feature detection such that users can apply advanced machine learning and artificial intelligence (AI) without the need for a deep understanding of existing algorithms and techniques. Embodiments of the present disclosure provide systems and methods than enable easy access to a suite of machine learning algorithms and techniques, an intuitive interface for training an AI to recognize image features based on geometric “correct and refine” recursion, and real-time visualizations of training effectiveness. |
| FILED | Friday, August 30, 2019 |
| APPL NO | 16/557386 |
| ART UNIT | 2666 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/4642 (20130101) G06K 9/4652 (20130101) G06K 9/6212 (20130101) Original (OR) Class G06K 9/6217 (20130101) G06K 2009/6213 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11164080 | Modha |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | The present invention relates to unsupervised, supervised and reinforced learning via spiking computation. The neural network comprises a plurality of neural modules. Each neural module comprises multiple digital neurons such that each neuron in a neural module has a corresponding neuron in another neural module. An interconnection network comprising a plurality of edges interconnects the plurality of neural modules. Each edge interconnects a first neural module to a second neural module, and each edge comprises a weighted synaptic connection between every neuron in the first neural module and a corresponding neuron in the second neural module. |
| FILED | Friday, May 18, 2018 |
| APPL NO | 15/984167 |
| ART UNIT | 2124 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Original (OR) Class G06N 3/049 (20130101) G06N 3/063 (20130101) G06N 3/088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11164102 | Solgun et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York); Juelich Research Center (Jülich, Germany) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York); JUELICH RESEARCH CENTER (Jülich, Germany) |
| INVENTOR(S) | Firat Solgun (Ossining, New York); David P. DiVincenzo (Voerendaal, Netherlands) |
| ABSTRACT | Systems, computer-implemented methods, and computer program products to facilitate external port measurement of qubit port responses are provided. According to an embodiment, a computer-implemented method can comprise terminating, by a system operatively coupled to a processor, one or more qubit ports with different electrical connections. The computer-implemented method can also comprise determining, by the system, one or more qubit port responses from external port responses based on the terminating. In some embodiments, the computer-implemented method can further comprise determining, by the system, a multiport admittance function corresponding to at least two of the one or more qubit ports. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 16/808618 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/31702 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Pulse Technique H03K 19/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11164566 | Biadsy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Fadi Biadsy (New York, New York); Lidia Mangu (New York, New York); Hagen Soltau (Yorktown Heights, New York) |
| ABSTRACT | Methods and systems for automatic speech recognition and methods and systems for training acoustic language models are disclosed. In accordance with one automatic speech recognition method, an acoustic input data set is analyzed to identify portions of the input data set that conform to a general language and to identify portions of the input data set that conform to at least one dialect of the general language. In addition, a general language model and at least one dialect language model is applied to the input data set to perform speech recognition by dynamically selecting between the models in accordance with each of the identified portions. Further, speech recognition results obtained in accordance with the application of the models is output. |
| FILED | Monday, May 07, 2018 |
| APPL NO | 15/972719 |
| ART UNIT | 2658 — Linguistics, Speech Processing and Audio Compression |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 15/005 (20130101) G10L 15/18 (20130101) Original (OR) Class G10L 15/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11164733 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jian Gao (Richmond, California); Trent R. Northen (Walnut Creek, California) |
| ABSTRACT | Disclosed herein are compositions for ionizing a target and methods for making the compositions. In some embodiments, the compositions can include a structured substrate having a plurality of upright surface features, for example, microscale or nanoscale pillars, in contact with an initiator. Also disclosed herein are methods for ionizing targets. |
| FILED | Wednesday, October 05, 2016 |
| APPL NO | 15/759192 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/00 (20130101) H01J 49/14 (20130101) H01J 49/107 (20130101) H01J 49/161 (20130101) H01J 49/0409 (20130101) H01J 49/0418 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11164967 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Cree, Inc. (Durham, North Carolina) |
| ASSIGNEE(S) | Cree, Inc. (Durham, North Carolina) |
| INVENTOR(S) | Qingchun Zhang (Cary, North Carolina); Alexander V. Suvorov (Durham, North Carolina) |
| ABSTRACT | A power MOSFET includes a silicon carbide drift region having a first conductivity type, first and second well regions located in upper portions of the silicon carbide drift region that are doped with second conductivity dopants, and a channel region in a side portion of the first well region, an upper portion of the channel region having the first conductivity type, wherein a depth of the first well region is at least 1.5 microns and the depth of the first well region exceeds a distance between the first and second well regions. |
| FILED | Monday, August 12, 2019 |
| APPL NO | 16/538229 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/047 (20130101) H01L 21/26513 (20130101) H01L 29/086 (20130101) H01L 29/105 (20130101) H01L 29/0646 (20130101) H01L 29/0696 (20130101) H01L 29/1608 (20130101) H01L 29/7802 (20130101) Original (OR) Class H01L 29/7828 (20130101) H01L 29/66068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11164987 | Hopkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Frank K. Hopkins (Beavercreek, Ohio); Shamus P. McNamara (New Salisbury, Indiana); John G. Jones (Dayton, Ohio) |
| ABSTRACT | In accordance with various embodiments of the disclosed subject matter, a phototransistor comprises an NPN or PNP phototransistor having a base including a Si-region, a Ge-region, and a Ge—Si interface region wherein photons are absorbed in the Ge region and conduction-band electrons are attracted to the interface region such that the electrons' mobility is enhanced thereby. |
| FILED | Tuesday, May 19, 2020 |
| APPL NO | 16/877618 |
| ART UNIT | 2818 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/028 (20130101) H01L 31/1105 (20130101) Original (OR) Class H01L 31/1804 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11165821 | Stevens et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Systems and Technology Research, LLC (Woburn, Massachusetts) |
| ASSIGNEE(S) | SYSTEMS and TECHNOLOGY RESEARCH, LLC (Woburn, Massachusetts) |
| INVENTOR(S) | Mark Stevens (Bedford, Massachusetts); Gerard Titi (Ayer, Massachusetts); Nilanjan Dasgupta (Chelmsford, Massachusetts); Jeffrey Jackson (Salem, Massachusetts); Rurik Primiani (Somerville, Massachusetts); Nils Sandell (Somerville, Massachusetts) |
| ABSTRACT | A communication network authenticates the source of messages transmitted on a flat bus to determine the presence of spoofing events. A programmable intrusion detection device is connected to the bus at a fixed location and compiles templates for various tri-bit signal pulses that form the data transmitted as messages between network nodes. Each tri-bit template compares unique signal characteristics inherent in the signal waveform received by the device from each node, the unique characteristics being directly attributable to the physical topology of the network. In use, the device uses the templates to calculate an inferred source identifier for each message. The inferred source identifier is then compared against the declared source identifier, which is embedded in message metadata, to authenticate the message source. Any lack of reconciliation between the inferred and declared source identifiers causes the device to mark the message as spoofed and initiate a designated response. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/258000 |
| ART UNIT | 2435 — Cryptography and Security |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 19/04 (20130101) Electric Digital Data Processing G06F 21/55 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 12/40 (20130101) H04L 12/40136 (20130101) H04L 63/16 (20130101) H04L 63/126 (20130101) H04L 63/0876 (20130101) H04L 63/1483 (20130101) Original (OR) Class H04L 2463/146 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11160277 | Mortimer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jennifer C. Mortimer (Oakland, California); Robin A. Herbert (Richmond, California); Aindrila Mukhopadhyay (Oakland, California); Thomas T. Eng (Berkeley, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jennifer C. Mortimer (Oakland, California); Robin A. Herbert (Richmond, California); Aindrila Mukhopadhyay (Oakland, California); Thomas T. Eng (Berkeley, California) |
| ABSTRACT | The present invention provides for an herbicidal composition comprising a cholinium lysinate [Ch][Lys], and a method for controlling the growth of one or more plants, comprising applying the herbicidal composition thereof. |
| FILED | Monday, May 04, 2020 |
| APPL NO | 16/866453 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 37/44 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160489 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois); WASHINGTON UNIVERSITY IN ST. LOUIS (St. Louis, Missouri) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | John A. Rogers (Wilmette, Illinois); Michael Raymond Bruchas (St. Louis, Missouri); Jaewoong Jeong (Champaign, Illinois); Jordan Gary McCall (St. Louis, Missouri) |
| ABSTRACT | Provided are implantable, injectable and/or surface mounted biomedical devices and related methods for interfacing with a target tissue. The devices have a substrate, one or more microfluidic channels embedded in or supported by the substrate and a fluid actuator in operational communication with one or more reservoirs and responsive to a wireless control signal. The components of the device are specially configured and packaged to be ultra-thin and mechanically compliant. In some embodiments, the devices are self-powered and fully implantable. The devices can be shaped to provide injection in a minimally invasive manner, thereby avoiding unnecessary tissue damage and providing a platform for long-term implantation for interfacing with biological tissue. |
| FILED | Friday, July 01, 2016 |
| APPL NO | 15/738043 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/01 (20130101) A61B 5/0006 (20130101) A61B 5/0008 (20130101) A61B 5/24 (20210101) A61B 5/0031 (20130101) A61B 5/0084 (20130101) A61B 5/145 (20130101) A61B 5/291 (20210101) A61B 5/685 (20130101) A61B 5/4064 (20130101) Original (OR) Class A61B 5/4836 (20130101) A61B 5/6844 (20130101) A61B 5/6868 (20130101) A61B 5/14503 (20130101) A61B 2560/0412 (20130101) A61B 2562/12 (20130101) A61B 2562/028 (20130101) A61B 2562/164 (20130101) A61B 2562/0285 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/14276 (20130101) A61M 2205/3327 (20130101) A61M 2205/3561 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160887 | Miao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNM RAINFOREST INNOVATIONS (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| INVENTOR(S) | Yubin Miao (Albuquerque, New Mexico); Haixun Guo (Louisville, Kentucky) |
| ABSTRACT | The present invention is directed to novel non-invasive diagnostic tools/compounds comprising a cyclic peptide wherein the compound binds to a MSH receptor to image and treat cancers, especially, melanoma, including metastatic melanoma in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probes are capable of detecting cancerous melanoma cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and treatment of melanoma, including metastatic melanoma using non-invasive molecular imaging techniques. The novel probes of the present invention will also be useful to initiate therapy for melanoma as well as monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of melanoma/metastatic melanoma. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states. |
| FILED | Tuesday, February 05, 2019 |
| APPL NO | 16/267477 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0019 (20130101) A61K 9/0053 (20130101) A61K 45/06 (20130101) A61K 51/088 (20130101) Original (OR) Class Peptides C07K 14/685 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/60 (20130101) G01N 33/5743 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161147 | Carlsson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Johan A. Carlsson (Princeton, New Jersey) |
| ABSTRACT | According to various embodiments, a system for acoustic to electronic transduction is disclosed. The system includes a transducing medium configured to convert a received acoustic signal into a transduced electronic signal when a voltage is applied. The system further includes a high-pass filter coupled to the transducing medium, the high-pass filter configured to isolate the transduced signal from the applied voltage. |
| FILED | Friday, February 08, 2019 |
| APPL NO | 16/270787 |
| ART UNIT | 3645 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Methods or Apparatus for Generating or Transmitting Mechanical Vibrations of Infrasonic, Sonic, or Ultrasonic Frequency, for Performing Mechanical Work in General B06B 1/0292 (20130101) Original (OR) Class Transmission H04B 11/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161175 | Wang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Jian-Ping Wang (Shoreview, Minnesota); Bin Ma (Roseville, Minnesota); Jinming Liu (Minneapolis, Minnesota); Yiming Wu (Shoreview, Minnesota); YanFeng Jiang (Minneapolis, Minnesota) |
| ABSTRACT | Example nanoparticles may include an iron-based core, and a shell. The shell may include a non-magnetic, anti-ferromagnetic, or ferrimagnetic material. Example alloy compositions may include an iron-based grain, and a grain boundary. The grain boundary may include a non-magnetic, anti-ferromagnetic, or ferrimagnetic material. Example techniques for forming iron-based core-shell nanoparticles may include depositing a shell on an iron-based core. The depositing may include immersing the iron-based core in a salt composition for a predetermined period of time. The depositing may include milling the iron-based core with a salt composition for a predetermined period of time. Example techniques for treating a composition comprising core-shell nanoparticles may include nitriding the composition. |
| FILED | Friday, October 06, 2017 |
| APPL NO | 16/340031 |
| ART UNIT | 1784 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/02 (20130101) Original (OR) Class B22F 1/0018 (20130101) B22F 9/04 (20130101) B22F 2301/35 (20130101) B22F 2302/20 (20130101) B22F 2304/054 (20130101) Alloys C22C 38/00 (20130101) C22C 38/001 (20130101) C22C 38/10 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 8/26 (20130101) C23C 8/50 (20130101) C23C 8/80 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/059 (20130101) H01F 1/0551 (20130101) H01F 1/0552 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11161369 — Graphic layers and related methods for incorporation of graphic layers into solar modules
| US 11161369 | Occidentale et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sistine Solar, Inc. (Somerville, Massachusetts) |
| ASSIGNEE(S) | Sistine Solar, Inc. (Somerville, Massachusetts) |
| INVENTOR(S) | Anthony John Occidentale (Bergenfield, New Jersey); Senthil Balasubramanian (Cambridge, Massachusetts); Jody Fu (San Francisco, California); Jonathan Mailoa (Cambridge, Massachusetts); Ido Salama (New York, New York); Samantha Holmes (New York, New York) |
| ABSTRACT | In some aspects, graphic layers for depicting a visible representation of an image along a surface of a photovoltaic module can include a plurality of substantially opaque isolated regions; and at least one substantially transparent contiguous region surrounding the substantially opaque isolated regions, wherein an outer surface of the at least one substantially transparent contiguous region comprises a matte surface finish. |
| FILED | Tuesday, December 06, 2016 |
| APPL NO | 15/370744 |
| ART UNIT | 1726 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Special Designs or Pictures B44F 1/06 (20130101) Original (OR) Class B44F 1/08 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/02 (20130101) H01L 31/048 (20130101) H01L 31/049 (20141201) H01L 31/055 (20130101) H01L 31/02162 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/23 (20141201) Climate Change Mitigation Technologies Related to Buildings, e.g Housing, House Appliances or Related End-user Applications Y02B 10/10 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161694 | Augustine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Chad Augustine (Evergreen, Colorado); David Levi Young (Golden, Colorado); Henry Ellis Johnston, Jr. (Golden, Colorado) |
| ABSTRACT | Methods and systems for thermal energy storage and enhanced oil recovery are described herein. In some embodiments, natural gas may be injected down a well which has been previously hydraulically fractured to store thermal energy and to stimulate the well to greater hydrocarbon production. |
| FILED | Thursday, July 18, 2019 |
| APPL NO | 16/515923 |
| ART UNIT | 3674 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Transport or Storage Devices, e.g Conveyors for Loading or Tipping, shop Conveyor Systems Or pneumatic Tube Conveyors B65G 5/005 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/26 (20130101) E21B 43/168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161865 | Mach et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Robert H. Mach (Wallingford, Pennsylvania); Sean Reilly (Philadelphia, Pennsylvania); Mehran Makvandi (Philadelphia, Pennsylvania); Kuiying Xu (Wallingford, Pennsylvania); Daniel A. Pryma (Bryn Mawr, Pennsylvania); Roger A. Greenberg (Bala Cynwyd, Pennsylvania) |
| ABSTRACT | The present disclosure relates to compounds of Formula I and II, wherein R1-R20 and FL are defined herein. Also provided are methods of targeting alpha-radiation to poly(ADP-ribose)polymerase 1 (PARP-1) enzyme expression, reducing proliferation of cancer cells, reducing proliferation of cancer cells, detecting intact and enzymatically active poly(ADP-ribose)polymerase 1 (PARP-1) enzyme expression, detecting PARP-1 enzyme expression in a subjects tissue sample, monitoring cancer treatment in a subject, or detecting a PARP-1 receptive cancer in a subject. |
| FILED | Thursday, May 24, 2018 |
| APPL NO | 16/616049 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/10 (20130101) A61K 51/047 (20130101) Heterocyclic Compounds C07D 487/06 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/027 (20130101) C07F 13/00 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/48 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/57496 (20130101) G01N 2333/91142 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161983 | Naskar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Amit K. Naskar (Knoxville, Tennessee); Ngoc A. Nguyen (Oak Ridge, Tennessee) |
| ABSTRACT | A solid polymer blend material comprising: (i) a lignin-acrylonitrile component containing a homogeneous blend of a lignin component and an acrylonitrile-containing rubber component; and (ii) a styrene-containing thermoplastic component that is non-elastomeric; wherein components (i) and (ii) are homogeneously dispersed in the polymer blend material. Methods for producing the blend material are also described. Methods for producing objects made of the blend material by melt extrusion are also described, comprising: (a) melt blending components (i) and (ii) to form a polymer blend in which components (i) and (ii) are homogeneously blended, wherein the polymer blend exhibits a melt viscosity of no more than 2000 Pa·s at a shear rate of 100-1000 s−1 and when heated to a temperature of no more than 240° C.; and (b) forming an object made of said polymer blend material. |
| FILED | Friday, January 25, 2019 |
| APPL NO | 16/257313 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/106 (20170801) B29C 64/118 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) Derivatives of Natural Macromolecular Compounds C08H 6/00 (20130101) Compositions of Macromolecular Compounds C08L 9/02 (20130101) C08L 9/02 (20130101) C08L 9/02 (20130101) C08L 25/06 (20130101) C08L 25/14 (20130101) C08L 55/02 (20130101) C08L 55/02 (20130101) C08L 55/02 (20130101) C08L 97/005 (20130101) Original (OR) Class C08L 97/005 (20130101) C08L 97/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162022 | Cannan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Chad Cannan (Lancaster, New York); Lewis Bartel (Albuquerque, New Mexico); Terrence Palisch (Richardson, Texas); David Aldridge (Albuquerque, New Mexico) |
| ASSIGNEE(S) | CARBO CERAMICS INC. (Houston, Texas); Sandia Corporation (Albuquerque, New Mexico) |
| INVENTOR(S) | Chad Cannan (Lancaster, New York); Lewis Bartel (Albuquerque, New Mexico); Terrence Palisch (Richardson, Texas); David Aldridge (Albuquerque, New Mexico) |
| ABSTRACT | Electrically conductive proppants and methods for detecting, locating, and characterizing same are provided. The electrically conductive proppant can include a substantially uniform coating of an electrically conductive material having a thickness of at least 500 nm. The method can include injecting a hydraulic fluid into a wellbore extending into a subterranean formation at a rate and pressure sufficient to open a fracture therein, injecting into the fracture a fluid containing the electrically conductive proppant, electrically energizing the earth at or near the fracture, and measuring three dimensional (x, y, and z) components of electric and magnetic field responses at a surface of the earth or in an adjacent wellbore. |
| FILED | Tuesday, January 21, 2020 |
| APPL NO | 16/747650 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/805 (20130101) Original (OR) Class Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/06 (20130101) C23C 14/35 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/25 (20130101) E21B 43/26 (20130101) E21B 43/267 (20130101) E21B 47/00 (20130101) E21B 47/092 (20200501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162703 | Zeifman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fraunhofer USA, Inc. (Plymouth, Michigan) |
| ASSIGNEE(S) | FRAUNHOFER USA, INC. (Plymouth, Michigan) |
| INVENTOR(S) | Michael Zeifman (Sharon, Massachusetts); Amine Lazrak (Boston, Massachusetts) |
| ABSTRACT | Systems and methods for characterization of retrofit opportunities are described. The methods may comprise computing, using at least one computing device disposed remote from a building and based at least in part on heating, ventilation and air conditioning (HVAC) runtime data associated with the building, one or more thermal characteristics of the building. In some embodiments, a model-predicted indoor temperature may be fitted against thermal data measured by a thermostat at the building. The thermal characteristic of the building may comprise a thermal insulation, an air leakage rate and/or an HVAC efficiency. The method may be used to determine, using the at least one computing device, suitability of the building for a retrofit opportunity to improve energy efficiency of the building. Determining the suitability may comprise evaluating the one or more thermal characteristics. The HVAC runtime data may be computed based on data received from a thermostat or a meter, such as an electric or a gas meter. |
| FILED | Friday, August 18, 2017 |
| APPL NO | 15/681306 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 11/63 (20180101) Original (OR) Class F24F 2110/10 (20180101) F24F 2140/60 (20180101) Measuring Electric Variables; Measuring Magnetic Variables G01R 21/006 (20130101) Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/042 (20130101) G05B 2219/2614 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 23/1917 (20130101) Electric Digital Data Processing G06F 30/13 (20200101) G06F 2119/06 (20200101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/063 (20130101) G06Q 50/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162861 | Kotovsky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Jack Kotovsky (Alameda, California); Taylor Bevis (Bothell, Washington) |
| ABSTRACT | Measurement of pressure of a fluid in a vessel using a cantilever spring in the vessel; a magnet connected to the cantilever spring in the vessel; an electromagnet outside of the vessel operatively connected to the magnet and the cantilever spring in the vessel, wherein the electromagnet induces movement of the magnet and the cantilever spring in the vessel, and wherein the movement is related to the pressure of the fluid in the vessel; a receiving coil operatively positioned relative to the magnet, wherein movement of the cantilever spring and the magnet in the vessel creates an electromotive response in the coil; and a controller analyzer connected to the receiving coil, wherein the controller analyzer uses the electromotive response in the coil for measuring the pressure of the fluid in the vessel. |
| FILED | Wednesday, April 24, 2019 |
| APPL NO | 16/393407 |
| ART UNIT | 2861 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 9/02 (20130101) G01L 9/007 (20130101) G01L 9/10 (20130101) G01L 9/12 (20130101) G01L 9/14 (20130101) Original (OR) Class G01L 9/0051 (20130101) G01L 9/0072 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162890 | Martin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Yves Martin (Ossining, New York); William Green (Irvington, New York); Theodore G. van Kessel (Millbrook, New York) |
| ABSTRACT | A sensor housing apparatus includes a housing having an enclosure and outer assembly, at least one flow path extending through the housing, a gas sensor disposed in the enclosure and a thermal mass. The thermal mass is mounted within the enclosure in thermal communication with the gas sensor, and is configured to transfer thermal energy from the gas sensor to an ambient environment surrounding the housing and minimize temperature gradients adjacent the gas sensor. |
| FILED | Thursday, January 02, 2020 |
| APPL NO | 16/732511 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/39 (20130101) G01N 21/1717 (20130101) Original (OR) Class G01N 2021/1731 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162904 | Reynolds et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | John G. Reynolds (San Ramon, California); Lara D. Leininger (Livermore, California); Thomas W. Myers (Livermore, California) |
| ABSTRACT | An inspection tester for testing a surface for suspected explosive substances includes a body unit, a breakable ampoule carried by the body unit, and an ionic explosive detecting reagent in the breakable ampoule wherein the body unit and the breakable ampoule are positioned to deliver the ionic explosive detecting reagent to the surface for testing the surface for the suspected explosive substances. The ionic explosive detecting reagent is a salt in a liquid state. |
| FILED | Friday, July 12, 2019 |
| APPL NO | 16/509828 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/78 (20130101) Original (OR) Class G01N 31/22 (20130101) G01N 33/227 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162977 | Schwarz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Udo Schwarz (Woodbridge, Connecticut); Eric Altman (Guilford, Connecticut); Hendrik Hölscher (Weingarten, Germany); Omur Erdinc Dagdeviren (Farmington, Connecticut) |
| ABSTRACT | Techniques for operating an atomic force microscope, the atomic force microscope comprising a cantilever and configured to image a surface of a sample using a probe tip coupled to the cantilever, the techniques comprising using a controller to perform: obtaining, based on at least one intrinsic parameter of the cantilever, a first quality factor and a first free oscillation amplitude, wherein the cantilever exhibits only one stable oscillation state when oscillating at the first free oscillation amplitude and operating at the first quality factor; and controlling the cantilever to exhibit the only one stable oscillation state by controlling the cantilever to oscillate at a fixed frequency at or near a resonance frequency of the cantilever, oscillate at the first free oscillation amplitude, and operate at the first quality factor. |
| FILED | Monday, December 21, 2015 |
| APPL NO | 15/538615 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 10/06 (20130101) G01Q 30/04 (20130101) G01Q 60/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163017 | Mostafavi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| INVENTOR(S) | Saman Mostafavi (Charlotte, North Carolina); Hong Yu (Fremont, California); Ajay Raghavan (Mountain View, California); Peter Kiesel (Palo Alto, California) |
| ABSTRACT | A monitoring system includes an array of optical sensors disposed within a transformer tank. Each optical sensor is configured to have an optical output that changes in response to a temperature within the transformer tank. An analyzer is coupled to the array of optical sensors. The analyzer is configured to determine a sensed temperature distribution based on the sensed temperature. The sensed temperature distribution is compared to an expected distribution. Exterior contamination of the transformer tank is detected based on the comparison. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 16/662655 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/1895 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/246 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 17/00 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 1/28 (20130101) G01R 15/207 (20130101) G01R 19/2513 (20130101) G01R 29/20 (20130101) G01R 31/52 (20200101) G01R 31/62 (20200101) Original (OR) Class G01R 31/72 (20200101) G01R 31/346 (20130101) G01R 35/02 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 27/02 (20130101) H01F 27/08 (20130101) Transmission H04B 3/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163115 | Gehl et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Michael Gehl (Albuquerque, New Mexico); Gregory A. Vawter (Corrales, New Mexico); Galen Hoffman (Albuquerque, New Mexico) |
| ABSTRACT | In an optical apparatus, an introduced semiconductor device is heterointegrated on a silicon-based platform containing a silicon-based waveguide. A polymeric waveguide is optically coupled to the introduced semiconductor device and overlies at least a portion of the silicon-based waveguide. The polymeric waveguide is conformed as a multimode interference (MMI) coupler between the introduced semiconductor device and the silicon-based waveguide. At least the polymeric waveguide, and in embodiments, also the silicon-based waveguide, is tapered with a shape that effectuates optical coupling to the silicon-based waveguide. |
| FILED | Tuesday, June 16, 2020 |
| APPL NO | 16/902429 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/1228 (20130101) Original (OR) Class G02B 6/12004 (20130101) G02B 2006/12069 (20130101) G02B 2006/12121 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163120 | Ardalan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ayar Labs, Inc. (Emeryville, California) |
| ASSIGNEE(S) | Ayar Labs, Inc. (Santa Clara, California) |
| INVENTOR(S) | Shahab Ardalan (Emeryville, California); Michael Davenport (Emeryville, California); Roy Edward Meade (Lafayette, California) |
| ABSTRACT | A package assembly includes a silicon photonics chip having an optical waveguide exposed at a first side of the chip and an optical fiber coupling region formed along the first side of the chip. The package assembly includes a mold compound structure formed to extend around second, third, and fourth sides of the chip. The mold compound structure has a vertical thickness substantially equal to a vertical thickness of the chip. The package assembly includes a redistribution layer formed over the chip and over a portion of the mold compound structure. The redistribution layer includes electrically conductive interconnect structures to provide fanout of electrical contacts on the chip to corresponding electrical contacts on the redistribution layer. The redistribution layer is formed to leave the optical fiber coupling region exposed. An optical fiber is connected to the optical fiber coupling region in optical alignment with the optical waveguide within the chip. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 16/685838 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/30 (20130101) Original (OR) Class G02B 6/122 (20130101) G02B 6/428 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11164681 | Cohen |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Samuel A. Cohen (Princeton, New Jersey) |
| ABSTRACT | According to various embodiments, an FRC fusion reactor is disclosed. The FRC fusion reactor includes a main chamber containing an FRC core and an energy and ash removal shell (EARS). The FRC fusion reactor further includes at least one divertor chamber connected to the main chamber via a divertor throat. The divertor chamber includes a plasma extruder positioned on a major axis of the FRC fusion reactor and a controllable distance along the major axis from the divertor throat. The plasma extruder has a diameter approximately ½ a diameter of the divertor throat and is configured to block plasma flow towards the FRC core to create a gap region between the FRC core and the EARS. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 16/808594 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Fusion Reactors G21B 1/13 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11164733 | Gao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jian Gao (Richmond, California); Trent R. Northen (Walnut Creek, California) |
| ABSTRACT | Disclosed herein are compositions for ionizing a target and methods for making the compositions. In some embodiments, the compositions can include a structured substrate having a plurality of upright surface features, for example, microscale or nanoscale pillars, in contact with an initiator. Also disclosed herein are methods for ionizing targets. |
| FILED | Wednesday, October 05, 2016 |
| APPL NO | 15/759192 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/00 (20130101) H01J 49/14 (20130101) H01J 49/107 (20130101) H01J 49/161 (20130101) H01J 49/0409 (20130101) H01J 49/0418 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11165064 | Xiong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOISE STATE UNIVERSITY (Boise, Idaho) |
| ASSIGNEE(S) | Boise State University (Boise, Idaho) |
| INVENTOR(S) | Hui Xiong (Boise, Idaho); Changjian Deng (Boise, Idaho); Jing Xu (Mountain View, California) |
| ABSTRACT | Systems, methods, and compositions are disclosed for a Li-substituted layered-tunneled O3/spinel Na(NixFeyMnz)O2 cathode material, Na0.87Li0.25Ni0.4Fe0.2Mn0.4O2+∂ (LS-NFM) for enhanced sodium ion storage and cycling stability. The LS-NFM electrode is prepared by adjusting the stoichiometric ratio of the Na ion over the sum of Li and transition metal ions below 1. The Rietveld refinement of XRD data indicates that the cathode is composed of 94% layered and 6% spinel components. When cycled at a high current density of 100 mA g−1, LS-NFM cathode exhibited a first-cycle Coulombic efficiency of 88% and reversible discharge capacity of 107 mAh g−1 after 50 cycles with the capacity retention of 95%. |
| FILED | Monday, October 07, 2019 |
| APPL NO | 16/594235 |
| ART UNIT | 1767 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/50 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/01 (20130101) C01P 2002/72 (20130101) C01P 2004/03 (20130101) C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) Original (OR) Class H01M 10/054 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11165387 | Lin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SunPower Corporation (San Jose, California) |
| ASSIGNEE(S) | SunPower Corporation (San Jose, California) |
| INVENTOR(S) | Yafu Lin (San Jose, California); Ryan Reagan (Hayward, California); Itai Suez (Hercules, California); Katherine Han (San Jose, California); Hai-Yue Han (San Jose, California) |
| ABSTRACT | Cyclical testing of electrically conductive bonding (ECB) is provided. Cyclical testing comprises high current flows using multiples of max operating currents and monitoring sensors with periods of no current to accelerate testing of electrical connections employing ECBs. |
| FILED | Tuesday, March 03, 2020 |
| APPL NO | 16/807312 |
| ART UNIT | 2852 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/66 (20200101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 40/36 (20141201) H02S 50/10 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11165686 | Heidelberger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Philip Heidelberger (Cortlandt Manor, New York); Dong Chen (Scarsdale, New York); Yutaka Sugawara (Eastchester, New York); Paul W. Coteus (Yorktown, New York) |
| ABSTRACT | A switch-connected dragonfly network and method of operating. A plurality of groups of row switches is organized according to multiple rows and columns, each row including multiple groups of row switches connected to form a two-level dragonfly network. A plurality of column switches interconnect groups of row switches along respective columns, a column switch associated with a corresponding group of row switches in a row. A switch port with a same logical port on a row switch at a same location in each group along the respective column connects to a same column switch. The switch-connected dragonfly network is expandable by adding additional rows, an added row comprising a two-level dragonfly network. A switch group of said added row associated with a column being connects to an available port at an existing column switch of said column by corresponding added S path link with no re-cabling of the switched network required. |
| FILED | Tuesday, August 07, 2018 |
| APPL NO | 16/057015 |
| ART UNIT | 2478 — Multiplex and VoIP |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/14 (20130101) H04L 45/24 (20130101) Original (OR) Class H04L 45/121 (20130101) H04L 49/1576 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11160458 | Rogers et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | John A. Rogers (Champaign, Illinois); Li Gao (Urbana, Illinois); Viktor Malyarchuk (Urbana, Illinois); Richard Chad Webb (Urbana, Illinois) |
| ABSTRACT | Provided are tissue-mounted devices and methods for monitoring a thermal transport property (e.g., thermal conductivity, thermal diffusivity, heat capacity) of tissue, such as skin. The devices conformally mount to the tissue and have one or more thermal actuators and a plurality of sensors. The actuator applies heat to the tissue and the sensors to detect a spatio temporal distribution of a physiological tissue parameter or physical property resulting from the heating. This spatio temporal information may be correlated with a rate, velocity and/or direction of blood flow, the presence of a vascular occlusion, circulation changes due to inflammation, hydration level and other physiological parameters. |
| FILED | Tuesday, August 11, 2015 |
| APPL NO | 15/501379 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/002 (20130101) A61B 5/015 (20130101) Original (OR) Class A61B 5/028 (20130101) A61B 5/0048 (20130101) A61B 5/0205 (20130101) A61B 5/0261 (20130101) A61B 5/318 (20210101) A61B 5/369 (20210101) A61B 5/389 (20210101) A61B 5/0537 (20130101) A61B 5/683 (20130101) A61B 5/02007 (20130101) A61B 5/4875 (20130101) A61B 5/6802 (20130101) A61B 5/6824 (20130101) A61B 5/6832 (20130101) A61B 2560/04 (20130101) A61B 2562/12 (20130101) A61B 2562/028 (20130101) A61B 2562/046 (20130101) A61B 2562/164 (20130101) A61B 2562/0271 (20130101) A61B 2562/0285 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160875 | Cui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| INVENTOR(S) | Honggang Cui (Lutherville, Maryland); Alfredo Quinones-Hinojosa (Bel Air, Maryland) |
| ABSTRACT | The present invention provides compositions comprising at least one biologically active agent (D) chemically conjugated to a peptide or oligopeptide with overall hydrophilicity (Pep). In some embodiments, the composition comprises D-Pep wherein the biologically active agents are linked to the Pep molecule via an chemical linker, such as amino acid linker. These compositions can be mixed with the other compositions to provide mixtures of nanofiber hydrogel structures that also can be used to locally deliver biologically active agents to tissues of interest. The methods and compositions disclosed herein are useful for sustained drug release when administered in situ to the tissue of interest. |
| FILED | Thursday, June 16, 2016 |
| APPL NO | 15/736818 |
| ART UNIT | 1649 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/196 (20130101) A61K 31/337 (20130101) A61K 31/407 (20130101) A61K 47/64 (20170801) A61K 47/6903 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161827 | Zhang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Trustees of Boston College (Chestnut Hill, Massachusetts) |
| ASSIGNEE(S) | The Trustees of Boston College (Chesnut Hill, Morocco) |
| INVENTOR(S) | Xiao-Xiang Zhang (Newton, Massachusetts); Kai Lang (Boston, Massachusetts) |
| ABSTRACT | In one aspect, the disclosure relates to a mode of asymmetric induction in radical processes based on sequential combination of enantiodifferentiative H-atom abstraction and stereoretentive radical substitution. Also disclosed is an asymmetric system for stereoselective synthesis of strained 5-membered cyclic sulfamides via radical 1,5-C—H amination of sulfamoyl azides. The disclosed metalloradical system can control the degree and sense of asymmetric induction in the catalytic radical C—H amination in a systematic manner. The disclosed system is applicable to a broad scope of substrates with different types of C(sp3)—H bonds and exhibits reactivity and selectivity, providing access to both enantiomers of useful 5-membered cyclic sulfamides in a highly enantioenriched form. Also disclosed are catalysts useful in these processes. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure. |
| FILED | Monday, April 06, 2020 |
| APPL NO | 16/840879 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/183 (20130101) B01J 2231/4283 (20130101) B01J 2531/845 (20130101) Heterocyclic Compounds C07D 285/10 (20130101) Original (OR) Class C07D 487/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162000 | Wynne et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| ASSIGNEE(S) | VIRGINIA COMMONWEALTH UNIVERSITY (Richmond, Virginia) |
| INVENTOR(S) | Kenneth J. Wynne (Midlothian, Virginia); Wei Zhang (Midlothian, Virginia) |
| ABSTRACT | A compound is provided, having the formula (I), wherein RS is a soft block polymer; wherein each T is independently a urethane or urea linkage; see formulae (A) and (B); wherein each RD is independently —CH3, —CH2CH3, —CH2CH2CH3, or —CH2CH2CH2CH3; wherein each R′D is independently —CH3, —CH2CH3, —CH2CH2CH3, —CH2CH2CH2CH3, or —ORD; and wherein each p is independently 1, 2, or 3. Compositions containing the compound, and methods of making and using the compound are provided. |
| FILED | Monday, November 12, 2018 |
| APPL NO | 16/188192 |
| ART UNIT | 1762 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/336 (20130101) C08G 77/54 (20130101) C08G 77/388 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/5465 (20130101) C08K 5/5465 (20130101) C08K 5/5465 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) C08L 75/04 (20130101) C08L 83/04 (20130101) C08L 83/08 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 171/02 (20130101) Original (OR) Class C09D 183/14 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 3/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162060 | Yang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yajia Yang (Los Angeles, California); Yufei Mao (Los Angeles, California); Pei-Yu E. Chiou (Los Angeles, California); Chi On Chui (Encino, California) |
| ABSTRACT | A novel Self-Locking Optoelectronic Tweezers (SLOT) for single microparticle manipulation across a large area is provided. DEP forces generated from ring-shape lateral phototransistors are utilized for locking single microparticles or cells in the dark state. The locked microparticles or cells can be selectively released by optically deactivating these locking sites. |
| FILED | Tuesday, October 29, 2019 |
| APPL NO | 16/667801 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) B01L 2200/0668 (20130101) B01L 2400/0454 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 5/005 (20130101) B03C 5/026 (20130101) B03C 2201/26 (20130101) Apparatus for Enzymology or Microbiology; C12M 1/42 (20130101) Original (OR) Class C12M 3/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/10 (20130101) G01N 2035/1046 (20130101) Optical Elements, Systems, or Apparatus G02B 21/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162080 | Wimmer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Research Foundation for The State of University New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Eckard Wimmer (East Setauket, New York); Steve Skiena (Setauket, New York); Steffen Mueller (Kings Point, New York); Bruce Futcher (Stony Brook, New York); Dimitris Papamichail (Newtown, Pennsylvania); John Robert Coleman (Blauvelt, New York); Jeronimo Cello (Port Jefferson, New York) |
| ABSTRACT | This invention provides an attenuated virus which comprises a modified viral genome containing nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce synonymous deoptimized codons into the genome. The instant attenuated virus may be used in a vaccine composition for inducing a protective immune response in a subject. The invention also provides a method of synthesizing the instant attenuated virus. Further, this invention further provides a method for preventing a subject from becoming afflicted with a virus-associated disease comprising administering to the subject a prophylactically effective dose of a vaccine composition comprising the instant attenuated virus. |
| FILED | Monday, July 16, 2018 |
| APPL NO | 16/036348 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/13 (20130101) A61K 39/145 (20130101) A61K 2039/5254 (20130101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Original (OR) Class C12N 2720/12361 (20130101) C12N 2740/15061 (20130101) C12N 2760/16061 (20130101) C12N 2760/16121 (20130101) C12N 2760/16134 (20130101) C12N 2760/16162 (20130101) C12N 2770/20061 (20130101) C12N 2770/24161 (20130101) C12N 2770/32061 (20130101) C12N 2770/32621 (20130101) C12N 2770/32634 (20130101) C12N 2770/32661 (20130101) C12N 2770/32662 (20130101) C12N 2770/32671 (20130101) C12N 2770/32721 (20130101) C12N 2770/32761 (20130101) C12N 2770/32762 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162192 | Gopinath et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona); CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Ashwin Gopinath (Pasadena, California); Paul Rothemund (Pasadena, California); Rishabh Shetty (Tempe, Arizona); Rizal Hariadi (Phoenix, Arizona) |
| ABSTRACT | Embodiments of the present disclosure relate generally to single molecule arrays. More particularly, the present disclosure provides materials and methods for generating single molecule arrays using bottom-up self-assembly processes. Materials and methods of the present disclosure can be used to generate single molecule arrays with nanoapertures (e.g., zero mode waveguides) and for carrying out rapid, point-of-care biomolecule detection and quantification. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/762024 |
| ART UNIT | 1639 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0046 (20130101) B01J 2219/00497 (20130101) B01J 2219/00596 (20130101) B01J 2219/00612 (20130101) B01J 2219/00722 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162858 | Wettels et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ONROBOT LOS ANGELES INC. (Los Angeles, California) |
| ASSIGNEE(S) | ONROBOT A/S (Odense SØ, Denmark) |
| INVENTOR(S) | Nicholas Wettels (Los Angeles, California); Keoni Dade (Riverside, California); Menuka Gamage (Canoga Park, California) |
| ABSTRACT | Provided are systems, devices, and methods for sensing location and forces. A robotic effector comprising a skin and a core can have a plurality of electrodes integrated in the skin and/or core. Upon interaction with a target object, the robotic effector may determine a total force and/or a location of the force by the target object on the robotic effector. Sensitivity and dynamic range of the robotic effector may improve by changing various configurations. |
| FILED | Monday, December 02, 2019 |
| APPL NO | 16/700024 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 13/082 (20130101) B25J 13/084 (20130101) B25J 15/08 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/205 (20130101) G01L 5/228 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162902 | Ragan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Regina Ragan (Irvine, California); Filippo Capolino (Irvine, California); William Thrift (Irvine, California) |
| ABSTRACT | Nanoarchitectures comprised of subwavelength metal nanosphere oligomers with uniform narrow gap spacings for plasmonic and metamaterial devices are described, as well as methods of fabrication thereof, a biosensor system based thereon, and methods of detection of pathogenic or other organisms (e.g., bacteria) using the same. |
| FILED | Friday, August 24, 2018 |
| APPL NO | 16/112608 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 2300/0663 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/04 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 13/02 (20130101) C25D 13/04 (20130101) C25D 13/22 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162977 | Schwarz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | Yale University (New Haven, Connecticut) |
| INVENTOR(S) | Udo Schwarz (Woodbridge, Connecticut); Eric Altman (Guilford, Connecticut); Hendrik Hölscher (Weingarten, Germany); Omur Erdinc Dagdeviren (Farmington, Connecticut) |
| ABSTRACT | Techniques for operating an atomic force microscope, the atomic force microscope comprising a cantilever and configured to image a surface of a sample using a probe tip coupled to the cantilever, the techniques comprising using a controller to perform: obtaining, based on at least one intrinsic parameter of the cantilever, a first quality factor and a first free oscillation amplitude, wherein the cantilever exhibits only one stable oscillation state when oscillating at the first free oscillation amplitude and operating at the first quality factor; and controlling the cantilever to exhibit the only one stable oscillation state by controlling the cantilever to oscillate at a fixed frequency at or near a resonance frequency of the cantilever, oscillate at the first free oscillation amplitude, and operate at the first quality factor. |
| FILED | Monday, December 21, 2015 |
| APPL NO | 15/538615 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 10/06 (20130101) G01Q 30/04 (20130101) G01Q 60/32 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11163113 | Namnabat et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| INVENTOR(S) | Soha Namnabat (Tucson, Arizona); Robert A. Norwood (Tucson, Arizona); Kyung-Jo Kim (Tucson, Arizona); Roland Himmelhuber (Tucson, Arizona) |
| ABSTRACT | An athermal optical waveguide structure such as an optical add drop multiplexer (OADM) or the like is fabricated by a method that includes forming a lower cladding layer on a substrate. A waveguiding core layer is formed on the lower cladding layer. An upper cladding layer is formed on the waveguiding core layer and the lower cladding layer a sol-gel material. The sol-gel material includes an organically modified siloxane and a metal oxide. A thermo-optic coefficient of the sol-gel material is adjusted by curing the sol-gel material for a selected duration of time at a selected temperature such that the thermo-optic coefficient of the sol-gel material compensates for a thermo-optic coefficient of at least the waveguiding core layer such that an effective thermo-optic coefficient of the optical waveguide structure at a specified optical wavelength and over a specified temperature range is reduced. |
| FILED | Tuesday, August 14, 2018 |
| APPL NO | 16/639824 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/56 (20130101) Compositions of Macromolecular Compounds C08L 83/04 (20130101) Optical Elements, Systems, or Apparatus G02B 6/1203 (20130101) G02B 6/1221 (20130101) Original (OR) Class G02B 6/12028 (20130101) G02B 6/29338 (20130101) G02B 2207/109 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11164661 — Integrated system for nucleic acid-based storage and retrieval of digital data using keys
| US 11164661 | Ceze et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| INVENTOR(S) | Luis Henrique Ceze (Seattle, Washington); Georg Seelig (Seattle, Washington) |
| ABSTRACT | In some embodiments, systems and methods for storing and/or retrieving digital information in a nucleic acid library are provided. In some embodiments, an integrated system comprising a nucleic acid synthesis device, a nucleic acid sequencing device, a computing device, and a nucleic acid library is provided. In some embodiments, a write request that associates a value with a key is received by the system, the system synthesizes nucleic acid molecules associated with the request, and stores the nucleic acid molecules in the nucleic acid library. In some embodiments, a read request for a key is received by the system, and the system sequences nucleic acid molecules from the nucleic acid library that are associated with the key. |
| FILED | Friday, April 08, 2016 |
| APPL NO | 15/565372 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 2219/00722 (20130101) Electric Digital Data Processing G06F 11/00 (20130101) G06F 16/00 (20190101) G06F 16/90 (20190101) G06F 16/901 (20190101) Static Stores G11C 7/00 (20130101) G11C 13/02 (20130101) G11C 29/00 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/00 (20190201) G16B 25/20 (20190201) G16B 30/00 (20190201) G16B 50/00 (20190201) G16B 50/20 (20190201) G16B 50/30 (20190201) Original (OR) Class G16B 50/40 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11162858 | Wettels et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ONROBOT LOS ANGELES INC. (Los Angeles, California) |
| ASSIGNEE(S) | ONROBOT A/S (Odense SØ, Denmark) |
| INVENTOR(S) | Nicholas Wettels (Los Angeles, California); Keoni Dade (Riverside, California); Menuka Gamage (Canoga Park, California) |
| ABSTRACT | Provided are systems, devices, and methods for sensing location and forces. A robotic effector comprising a skin and a core can have a plurality of electrodes integrated in the skin and/or core. Upon interaction with a target object, the robotic effector may determine a total force and/or a location of the force by the target object on the robotic effector. Sensitivity and dynamic range of the robotic effector may improve by changing various configurations. |
| FILED | Monday, December 02, 2019 |
| APPL NO | 16/700024 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 13/082 (20130101) B25J 13/084 (20130101) B25J 15/08 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/205 (20130101) G01L 5/228 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162988 | Hesterman |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Aerojet Rocketdyne, Inc. (Sacramento, California) |
| ASSIGNEE(S) | Aerojet Rocketdyne, Inc. (Redmond, Washington) |
| INVENTOR(S) | Bryce L. Hesterman (Sacramento, California) |
| ABSTRACT | An impedance measurement circuit includes a signal injector having a voltage input and a voltage output, a controllable switch, and a voltage drop device connected in parallel with the controllable switch between the voltage input and the voltage output. The voltage output is connected to a load. A voltage sensor is configured to measure a voltage across the load. A current sensor is configured to measure a current draw of the load. A computing device is configured to determine an impedance of the load at a frequency based on the measured voltage and the measured current. The computing device controls the switch based on the frequency. |
| FILED | Monday, December 04, 2017 |
| APPL NO | 16/768472 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Producing a Reactive Propulsive Thrust, Not Otherwise Provided for F03H 1/0087 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 19/0084 (20130101) G01R 19/0092 (20130101) G01R 27/02 (20130101) Original (OR) Class Systems for Regulating Electric or Magnetic Variables G05F 1/613 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11165073 | Junaedi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRECISION COMBUSTION, INC. (North Haven, Connecticut) |
| ASSIGNEE(S) | Precision Combustion, Inc. (North Haven, Connecticut) |
| INVENTOR(S) | Christian Junaedi (Cheshire, Connecticut); Subir Roychoudhury (Madison, Connecticut); Saurabh Vilekar (Woodbridge, Connecticut); Kyle Hawley (Woodbury, Connecticut) |
| ABSTRACT | An individual solid oxide cell (SOC) constructed of a sandwich configuration including in the following order: an in oxygen electrode, a solid oxide electrolyte, a fuel electrode, a fuel manifold, and at least one layer of mesh. In one embodiment, the mesh supports a reforming catalyst resulting in a solid oxide fuel cell (SOFC) having a reformer embedded therein. The reformer-modified SOFC functions internally to steam reform or partially oxidize a gaseous hydrocarbon, e.g. methane, to a gaseous reformate of hydrogen and carbon monoxide, which is converted in the SOC to water, carbon dioxide, or a mixture thereof, and an electrical current. In another embodiment, an electrical insulator is disposed between the fuel manifold and the mesh resulting in a solid oxide electrolysis cell (SOEC), which functions to electrolyze water and/or carbon dioxide. |
| FILED | Monday, October 16, 2017 |
| APPL NO | 16/336158 |
| ART UNIT | 1725 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/00 (20130101) C25B 1/04 (20130101) C25B 9/19 (20210101) C25B 9/70 (20210101) C25B 9/77 (20210101) C25B 11/00 (20130101) C25B 15/02 (20130101) C25B 15/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/12 (20130101) H01M 8/184 (20130101) H01M 8/0258 (20130101) H01M 8/0625 (20130101) H01M 8/0631 (20130101) H01M 8/2425 (20130101) H01M 8/2483 (20160201) H01M 8/04037 (20130101) Original (OR) Class H01M 2008/1293 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 60/36 (20130101) Y02E 60/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11165467 | Garon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of NASA (Washington, District of Columbia) |
| INVENTOR(S) | Howard Garon (Lanham, Maryland); David Caruth (Arlington, Virginia); Obadiah Kegege (Greenbelt, Maryland); Frank Stocklin (Greenbelt, Maryland); Victor Sank (Lanham, Maryland) |
| ABSTRACT | A high data rate signal combiner (HDRSC), including: a first analog to digital converter (ADC) configured to convert a first radio frequency (RF) signal from a first antenna into a first digital signal; a second ADC configured to convert a second RF signal from a second antenna into a second digital signal; a first circular buffer configured to store the first digital signal from the first ADC; a second circular buffer configured to store the second digital signal from the second ADC; a cross-correlator configured to cross correlate the first digital signal and the second digital signal; a lag peak search circuit configured to determine the location of a peak in the output of the cross-correlator; a vector adder circuit configured to combine the first digital signal and the second digital signal with a delay on one of the first signal and the second digital signal based upon the location of the peak in the output of the cross-correlator; and a digital to analog converter (DAC) configured to convert the combined digital signal into an analog signal. |
| FILED | Monday, January 25, 2021 |
| APPL NO | 17/156835 |
| ART UNIT | 2633 — Digital Communications |
| CURRENT CPC | Transmission H04B 7/024 (20130101) Original (OR) Class H04B 7/0854 (20130101) H04B 7/0868 (20130101) H04B 7/1851 (20130101) H04B 7/18523 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11160826 | Demorrow et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Sharon Demorrow (Temple, Texas); Matthew MacMillin (Harker Height, Texas) |
| ABSTRACT | The present disclosure is concerned with cholesterol lowering agents including, but not limited to, statins and cyclodextrins, for the treatment of hepatic encephalopathy. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Thursday, October 24, 2019 |
| APPL NO | 16/663217 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/724 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11160833 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seatlle, Washington) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California); Seattle Children's Hospital (Seattle, Washington) |
| INVENTOR(S) | Yvonne Y. Chen (Los Angeles, California); Eugenia Zah (Los Angeles, California); Michael C. Jensen (Seattle, Washington) |
| ABSTRACT | A CD19-OR-CD20 chimeric antigen receptor (CAR) protein construct is provided. Also provided are nucleic acids encoding the CD19-OR-CD20 CAR; and methods of use, e.g. in the treatment of B cell malignancies. The CD19-OR-CD20 CAR of the invention is a bispecific CAR that can trigger T-cell activation upon detection of either CD19 or CD20 (or both). It is a single molecule that confers two-input recognition capability upon human T cells engineered to stably express this CAR. |
| FILED | Tuesday, September 22, 2020 |
| APPL NO | 17/028701 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) A61K 2039/505 (20130101) Peptides C07K 14/7051 (20130101) C07K 14/70521 (20130101) C07K 14/70596 (20130101) C07K 16/46 (20130101) C07K 16/2803 (20130101) C07K 16/2887 (20130101) C07K 2317/31 (20130101) C07K 2317/622 (20130101) C07K 2319/03 (20130101) C07K 2319/40 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11161684 | Ocasio et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | The United States Government as represented by the Department of Veterans Affairs (Washington, District of Columbia); University of Pittsburgh Of The Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Sabah Ocasio (Syracuse, New York); Heather Caron (Syracuse, New York); Garrett G. Grindle (Pittsburgh, Pennsylvania); Rory A. Cooper (Gibsonia, Pennsylvania); Benjamin Gebrosky (Pittsburgh, Pennsylvania); Katherine E. Gaines (Versailles, Kentucky) |
| ABSTRACT | A device for preventing immediate access to an object such as a key to a gun safety lock includes a platform adapted to receive the object. A container receives the platform and object. The container is filled with a fusible liquid such as water, the water is frozen and forms a body around the object. The container may include indicia such as photographs, quick response codes and telephone numbers for suicide prevention hotlines. |
| FILED | Friday, September 18, 2020 |
| APPL NO | 17/025002 |
| ART UNIT | 3736 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 25/205 (20130101) B65D 85/72 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/0723 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11161896 | He et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| INVENTOR(S) | Xiaohua He (Richmond, California); Daniela Mavrici (Oakland, California) |
| ABSTRACT | Monoclonal antibodies against bacterial proteins that confer resistance to the antibiotic colistin and hybridomas that produce such monoclonal antibodies are described. The monoclonal antibodies have a strong affinity for MCR proteins and may be used in detection methods and kits to detect the presence of MCR proteins including variants thereof in a sample. |
| FILED | Thursday, March 14, 2019 |
| APPL NO | 16/353467 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/1217 (20130101) Original (OR) Class C07K 2317/10 (20130101) C07K 2317/24 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6845 (20130101) G01N 33/56911 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11162143 | He |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Kansas (Lawrence, Kansas); Kansas State University Research Foundation (Manhattan, Kansas) |
| ASSIGNEE(S) | The University of Kansas (Lawrence, Kansas); Kansas State University Research Foundation (Manhattan, Kansas) |
| INVENTOR(S) | Mei He (Gainesville, Florida) |
| ABSTRACT | Methods for producing engineered exosomes and other vesicle-like biological targets, including allowing a target vesicle-like structure to react and bind with immunomagnetic particles; capturing the immunomagnetic particle/vesicle complex by applying a magnetic field; further engineering the captured vesicles by surface modifying with additional active moieties or internally loading with active agents; and releasing the engineered vesicle-like structures, such as by photolytically cleaving a linkage between the particle and engineered vesicle-like structures, thereby releasing intact vesicle-like structures which can act as delivery vehicles for therapeutic treatments. |
| FILED | Wednesday, April 21, 2021 |
| APPL NO | 17/236561 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6901 (20170801) A61K 49/0097 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) B01L 3/502761 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/015 (20130101) B03C 1/30 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/574 (20130101) G01N 33/5434 (20130101) G01N 33/54333 (20130101) G01N 2446/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11165505 | Gordon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE (Gaithersburg, Maryland) |
| INVENTOR(S) | Joshua Ari Gordon (Lafayette, Colorado); Christopher Lee Holloway (Boulder, Colorado) |
| ABSTRACT | A quantum atomic receiving antenna includes: a probe laser; a coupling laser; an atomic vapor cell that includes: a spherically-shaped or parallelepiped-shaped atomic vapor space and Rydberg antenna atoms that undergo a radiofrequency Rydberg transition to produce quantum antenna light from probe light such that an intensity of the quantum antenna light depends on an amount of radiofrequency radiation received by the Rydberg antenna atoms, the quantum antenna light including a strength, direction and polarization of the radiofrequency radiation; and a quantum antenna light detector in optical communication with the atomic vapor cell. |
| FILED | Thursday, February 11, 2021 |
| APPL NO | 17/173476 |
| ART UNIT | 2636 — Optical Communications |
| CURRENT CPC | Transmission H04B 10/70 (20130101) H04B 10/503 (20130101) H04B 10/532 (20130101) Original (OR) Class H04B 2210/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11161626 | Washington, II et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | William J. Washington, II (North Potomac, Maryland); Christian Jordan (Baltimore, Maryland) |
| ABSTRACT | A bag unlocking method includes receiving, by a bag handling system, a bag during a check-in process. The bag handling system identifies, from a travel carrier system, traveler information corresponding to the bag. A securing device of the bag is programmed, using an unlock code pertaining to the traveler information. The bag handling system reads a bag tag of the bag at a baggage inspection station, and determines the unlock code pertaining to the bag tag. The bag handling system transmits the unlock code to cause the securing device to unlock at the baggage inspection station. |
| FILED | Tuesday, February 23, 2021 |
| APPL NO | 17/182870 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Ground or Aircraft-carrier-deck Installations Specially Adapted for Use in Connection With Aircraft; Designing, Manufacturing, Assembling, Cleaning, Maintaining or Repairing Aircraft, Not Otherwise Provided For; Handling, Transporting, Testing or Inspecting Aircraft Components, Not Otherwise Provided for B64F 1/366 (20130101) Original (OR) Class B64F 1/368 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 11163906 | Zakour |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Orbis Technologies, Inc. (Annapolis, Maryland) |
| ASSIGNEE(S) | Orbis Technologies, Inc. (Annapolis, Maryland) |
| INVENTOR(S) | Elias Zakour (Severna Park, Maryland) |
| ABSTRACT | Methods, systems and computer program products are provided to automate redaction of data and metadata. Without modification of the underlying source code, a user may modify, add or remove rules and/or templates for governing redaction of data and metadata of source artifacts. Additionally, the system may automatically infer relationships between modified metadata parameters from application updates and normalized metadata parameters. In some cases, the system may add metadata to the redacted work products for compliance or other purposes. Additionally, redacted work products may comprise redacted source artifacts and a list of rules and/or templates applied to the source artifacts during redaction. |
| FILED | Thursday, October 04, 2018 |
| APPL NO | 16/151694 |
| ART UNIT | 2432 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/22 (20190101) G06F 21/6254 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 11162061 | Yeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTH FLORIDA (Tampa, Florida) |
| INVENTOR(S) | Daniel H. Yeh (Tampa, Florida); Onur Y. Ozcan (Tampa, Florida); Robert A. Bair (Tampa, Florida) |
| ABSTRACT | In one embodiment, a concentrically baffled reactor includes an outer housing that defines an interior space, an inlet through which material can be delivered into the interior space, an outlet through which material can be removed from the interior space, and multiple concentric baffles within the interior space that define multiple concentric reactor zones through which the material can sequentially flow to the outlet. |
| FILED | Wednesday, April 24, 2019 |
| APPL NO | 16/393464 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 21/003 (20130101) B01D 21/009 (20130101) B01D 21/0042 (20130101) B01D 21/0045 (20130101) B01D 21/0066 (20130101) B01D 21/245 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/006 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/02 (20130101) C02F 1/5281 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/34 (20130101) C12M 27/20 (20130101) Original (OR) Class C12M 29/04 (20130101) C12M 29/18 (20130101) C12M 41/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 11164330 | Warnaar |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
| ASSIGNEE(S) | Applied Research Associates, Inc. (Albuquerque, New Mexico) |
| INVENTOR(S) | Dirk B. Warnaar (Raleigh, North Carolina) |
| ABSTRACT | Systems and techniques for determining a list of geographic location candidates from an image of an environment are described. Open source data indicative of the earth's surface may be obtained and combined into grids to create region data to gain a representation of the earth's surface within each grid cell. An image of an environment may be obtained from an unknown camera. Image characteristics may be compared to the region data to determine error between the image characteristics and projections of the region data. A list of lowest error geographic location candidates may be determined and provided to the user. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 16/818552 |
| ART UNIT | 2482 — Recording and Compression |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/04 (20130101) Image Data Processing or Generation, in General G06T 7/73 (20170101) Original (OR) Class G06T 7/80 (20170101) G06T 2207/30244 (20130101) Pictorial Communication, e.g Television H04N 13/111 (20180501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 11164102 | Solgun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York); Juelich Research Center (Jülich, Germany) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York); JUELICH RESEARCH CENTER (Jülich, Germany) |
| INVENTOR(S) | Firat Solgun (Ossining, New York); David P. DiVincenzo (Voerendaal, Netherlands) |
| ABSTRACT | Systems, computer-implemented methods, and computer program products to facilitate external port measurement of qubit port responses are provided. According to an embodiment, a computer-implemented method can comprise terminating, by a system operatively coupled to a processor, one or more qubit ports with different electrical connections. The computer-implemented method can also comprise determining, by the system, one or more qubit port responses from external port responses based on the terminating. In some embodiments, the computer-implemented method can further comprise determining, by the system, a multiport admittance function corresponding to at least two of the one or more qubit ports. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 16/808618 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/31702 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class Pulse Technique H03K 19/195 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11162858 | Wettels et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ONROBOT LOS ANGELES INC. (Los Angeles, California) |
| ASSIGNEE(S) | ONROBOT A/S (Odense SØ, Denmark) |
| INVENTOR(S) | Nicholas Wettels (Los Angeles, California); Keoni Dade (Riverside, California); Menuka Gamage (Canoga Park, California) |
| ABSTRACT | Provided are systems, devices, and methods for sensing location and forces. A robotic effector comprising a skin and a core can have a plurality of electrodes integrated in the skin and/or core. Upon interaction with a target object, the robotic effector may determine a total force and/or a location of the force by the target object on the robotic effector. Sensitivity and dynamic range of the robotic effector may improve by changing various configurations. |
| FILED | Monday, December 02, 2019 |
| APPL NO | 16/700024 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 13/082 (20130101) B25J 13/084 (20130101) B25J 15/08 (20130101) Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/205 (20130101) G01L 5/228 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11165213 | Staver |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BAE SYSTEMS Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Philip R. Staver (Wilton, New Hampshire) |
| ABSTRACT | An optical system including a first lens element having an optical center, a second lens element having an optical center spaced apart from the first lens element and oriented such that a beam passing through the optical center of said first lens element will also pass straight the optical center of the second lens element, the beam defining an optical path; and at least one planar, optical slab configured to be movable between at least two positions, a first position wherein at least a portion of a planar surface of the optical slab is disposed between the first and second lens elements such that a beam transmitted therethrough also passes through the planar, optical slab and a second position wherein the planar, optical slab is fully outside of the optical path created by the first and second lens elements. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 16/448878 |
| ART UNIT | 2872 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 27/10 (20130101) G02B 27/0927 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/0071 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, November 02, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page