FedInvent™ Patents
Patent Details for Tuesday, December 14, 2021
This page was updated on Wednesday, December 15, 2021 at 06:01 PM GMT
Department of Health and Human Services (HHS)
| US 11197467 | Regev et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts); The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Oren Parnas (Jerusalem, Israel); Marko Jovanovic (Boston, Massachusetts); Nir Hacohen (Brookline, Massachusetts); Thomas Eisenhaure (North Reading, Massachusetts) |
| ABSTRACT | The invention involves a method for modulating leukocyte activity, comprising delivering to a leukocyte a vector containing nucleic acid molecule(s), whereby the leukocyte contains Cas9 and the vector expresses one or more RNAs to guide the Cas9 to introduce mutations in one or more target genetic loci in the leukocyte, thereby modulating expression of one or more genes expressed in the leukocyte. The invention also involves identifying genes associated with leukocyte responses and experimental modeling of aberrant leukocyte activation and diseases associated with leukocytes by introducing mutations into leukocytes. The invention comprehends testing putative treatments with such models, e.g., testing putative chemical compounds that may be pharmaceutically relevant for treatment or gene therapy that may be relevant for treatment, or combinations thereof. The invention allows for the study of genetic diseases and putative treatments to better understand and alleviate leukocyte associated diseases. |
| FILED | Friday, March 24, 2017 |
| APPL NO | 15/468652 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 67/0271 (20130101) Original (OR) Class A01K 67/0275 (20130101) A01K 2207/05 (20130101) A01K 2207/12 (20130101) A01K 2217/052 (20130101) A01K 2217/077 (20130101) A01K 2227/105 (20130101) A01K 2267/0312 (20130101) A01K 2267/0331 (20130101) A01K 2267/0362 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Peptides C07K 2319/09 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/04 (20130101) C12N 9/22 (20130101) C12N 15/85 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 15/907 (20130101) C12N 15/1082 (20130101) C12N 2310/10 (20130101) C12N 2310/20 (20170501) C12N 2310/531 (20130101) C12N 2310/3513 (20130101) C12N 2320/12 (20130101) C12N 2330/31 (20130101) C12N 2330/51 (20130101) C12N 2740/15043 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197836 | Fahl et al. |
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| FUNDED BY |
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| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | William E. Fahl (Madison, Wisconsin); Arnold E. Ruoho (Madison, Wisconsin); Minesh Mehta (Sun Prairie, Wisconsin) |
| ABSTRACT | Vasoconstrictors are administered topically to provide protection against the adverse effects, e.g., alopecia, mucositis or dermatitis, induced by chemotherapy or radiotherapy. Appropriate dosages and formulations of topical vasoconstrictors are provided. Methods for the use of such compositions are also provided. |
| FILED | Friday, November 06, 2015 |
| APPL NO | 14/934275 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/006 (20130101) A61K 9/0014 (20130101) A61K 31/137 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/10 (20130101) A61K 47/12 (20130101) A61K 47/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197864 | Reitz et al. |
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| FUNDED BY |
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| APPLICANT(S) | Biohaven Pharmaceutical Holding Company Limited (B (New Haven, Connecticut) |
| ASSIGNEE(S) | Biohaven Pharmaceutical Holding Company Limited (New Haven, Connecticut) |
| INVENTOR(S) | Allen B. Reitz (Landsdale, Pennsylvania); Garry Robert Smith (Royersford, Pennsylvania) |
| ABSTRACT | Pharmaceutical compositions of the invention include substituted riluzole pro drugs useful for the treatment of amyotrophic lateral sclerosis (ALS) and related disorders through the release of riluzole, especially to avoid patient to patient variability in first pass, hepatic metabolism promoted by Cyp 1∧2. Pro-drugs of riluzole have enhanced stability to hepatic metabolism and are delivered into systemic circulation by oral administration, and then cleaved to release riluzole in the plasma via either an enzymatic or general biophysical release process. The invention further includes pro-drugs of riluzole useful for the treatment of disease states that can be treated with riluzole through the release of riluzole from a pro-drug agent. |
| FILED | Monday, July 22, 2019 |
| APPL NO | 16/518008 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/428 (20130101) A61K 31/454 (20130101) A61K 31/496 (20130101) A61K 31/541 (20130101) Original (OR) Class A61K 31/4439 (20130101) A61K 31/4725 (20130101) A61K 31/5377 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197871 | Miller et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Jordan D. Miller (Rochester, Minnesota); Bin Zhang (Rochester, Minnesota) |
| ABSTRACT | This document provides methods and materials involved in treating cardiovascular conditions such as calcific aortic valve stenosis. For example, methods and materials for using sGC agonists or a combination of sGC agonists and PDE5A inhibitors to reduce calcification of heart valves and/or vessels or to slow progression of aortic sclerosis to calcific aortic valve stenosis are provided. |
| FILED | Tuesday, December 17, 2019 |
| APPL NO | 16/717302 |
| ART UNIT | 1627 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/197 (20130101) A61K 31/197 (20130101) A61K 31/416 (20130101) A61K 31/416 (20130101) A61K 31/506 (20130101) A61K 31/506 (20130101) A61K 31/519 (20130101) A61K 31/519 (20130101) A61K 31/635 (20130101) Original (OR) Class A61K 31/4985 (20130101) A61K 31/4985 (20130101) A61K 31/5377 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197876 | Christofidou-Solomidou et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE TRUSIEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania); THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Melpo Christofidou-Solomidou (Eagleville, Pennsylvania); Angela Haczku (Davis, California) |
| ABSTRACT | The invention provides compositions and methods for treating asthma in a subject in need thereof comprising administering chemically synthesized secoisolaricirecinol diglucoside (SDG), and in particular, a racemic mixture of the SDG (LGM2605), stereoisomers thereof, metabolites thereof, and analogs thereof. Also provided are methods for treating or preventing ozone-induced damage in a subject in need thereof. |
| FILED | Friday, October 05, 2018 |
| APPL NO | 16/153494 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/7032 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/06 (20180101) A61P 39/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197882 | Painter et al. |
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| FUNDED BY |
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| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | George R. Painter (Atlanta, Georgia); Gregory R. Bluemling (Decatur, Georgia); Michael G. Natchus (Alpharetta, Georgia); David Guthrie (Avondale Estates, Georgia) |
| ABSTRACT | This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds. |
| FILED | Friday, December 07, 2018 |
| APPL NO | 16/755779 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7068 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197883 | Yeo et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Eugene Yeo (La Jolla, California); Sebastian Markmiller (La Jolla, California); En-Ching Luo (La Jolla, California) |
| ABSTRACT | Disclosed herein are UBAP2L targeting agents and use of such agents for the treatment of a neurodegenerative disorder. Further disclosed herein are methods of monitoring the progression of a neurodegenerative disorder and methods of determining the efficacy of a neurodegenerative disorder therapy. |
| FILED | Tuesday, June 04, 2019 |
| APPL NO | 16/431486 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197888 | Ndinguri et al. |
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| FUNDED BY |
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| APPLICANT(S) | Eastern Kentucky University (Richmond, Kentucky) |
| ASSIGNEE(S) | Eastern Kentucky University (Richmond, Kentucky) |
| INVENTOR(S) | Margaret Ndinguri (Richmond, Kentucky); Lindsay Calderon (Lexington, Kentucky) |
| ABSTRACT | The conjugation of luteinizing hormone-releasing hormone (LHRH) with activated cisplatin using a malonate linker gives rise to a new Platinum-LHRH conjugate that effectively targets tumor cells that express the LHRH receptor. The Pt-LHRH conjugate may be used in a method for killing or inhibiting the growth of a tumor cell, especially in late state, highly invasive and aggressive stage IV tumors and in reoccurring tumors. |
| FILED | Friday, October 12, 2018 |
| APPL NO | 16/159232 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 33/243 (20190101) Original (OR) Class A61K 47/64 (20170801) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 15/0093 (20130101) Peptides C07K 7/23 (20130101) C07K 19/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197897 | Pamer et al. |
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| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Eric Pamer (Montclair, New Jersey); Peter McKenney (New York, New York); Silvia Caballero (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to methods and compositions for reducing the risk and severity of vancomycin-resistant Enterococci infection or colonization. It is based, at least in part, on the discovery that a restricted fraction of the gut microbiota, including the bacteria Clostridium scindens and/or the bacteria Blautia producta contribute substantially to resistance against vancomycin-resistant Enterococci infection or colonization. Without being bound by any particular theory, it is believed that this is achieved through the biosynthesis of secondary bile acids in the case of Clostridium scindens. |
| FILED | Friday, May 08, 2020 |
| APPL NO | 16/870634 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0031 (20130101) A61K 9/0043 (20130101) A61K 9/0053 (20130101) A61K 35/74 (20130101) A61K 35/741 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) Enzymes C12Y 101/00 (20130101) C12Y 101/01201 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197912 | Ma et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRIM-edicine, Inc. (Columbus, Ohio) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | Jianjie Ma (Powell, Ohio); Jacob S. Yount (Columbus, Ohio); Matthew A. Sermersheim (Nashville, Tennessee); Adam D. Kenney (Columbus, Ohio); Xinyu Zhou (Hilliard, Ohio); Bryan A. Whitson (Westerville, Ohio); Nahush A. Mokadam (Upper Arlington, Ohio); Tao Tan (Columbus, Ohio); Chuanxi Cai (Powell, Ohio) |
| ABSTRACT | Compositions for and methods of preventing, reversing or treating viral infection-induced organ failure provided. The compositions are also suitable for treating and/or preventing COVID-19 and influenza. The compositions and methods employ MG53, which can be in the form of recombinant human MG53. The MG53 may also be administered as a composition that expresses and releases MG53 after in vivo administration of said composition to a subject. |
| FILED | Thursday, February 25, 2021 |
| APPL NO | 17/184781 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197923 | Stinchcomb et al. |
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| FUNDED BY |
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| APPLICANT(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Dan Stinchcomb (Fort Collins, Colorado); Jorge E. Osorio (Mount Horeb, Wisconsin); O'Neil Wiggan (Fort Collins, Canada) |
| ABSTRACT | Embodiments herein relate to compositions of and methods for live viruses. In certain embodiments, a live, attenuated virus composition includes, but is not limited to, one or more live, attenuated viruses and compositions to reduce inactivation and/or degradation of the live, attenuated virus. In other embodiments, the live, attenuated virus composition may be a vaccine composition. In yet other compositions, a live, attenuated virus composition may include at least one carbohydrate, at least one protein and at least one high molecular weight surfactants for reducing inactivation and/or degradation of the live, attenuated virus. |
| FILED | Friday, November 22, 2019 |
| APPL NO | 16/692488 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 47/26 (20130101) A61K 47/36 (20130101) A61K 47/42 (20130101) A61K 2039/70 (20130101) A61K 2039/5254 (20130101) A61K 2039/55555 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 2650/58 (20130101) Compositions of Macromolecular Compounds C08L 71/02 (20130101) C08L 2203/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10051 (20130101) C12N 2710/10061 (20130101) C12N 2710/24151 (20130101) C12N 2710/24161 (20130101) C12N 2760/16051 (20130101) C12N 2760/16061 (20130101) C12N 2760/18411 (20130101) C12N 2770/24134 (20130101) C12N 2770/24151 (20130101) C12N 2770/24161 (20130101) C12N 2770/36151 (20130101) C12N 2770/36161 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197925 | Kawaoka et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin) |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Gabriele Neumann (Madison, Wisconsin); Jihui Ping (Madison, Wisconsin) |
| ABSTRACT | The invention provides a composition useful to prepare high titer influenza B viruses, e.g., in the absence of helper virus, which includes internal genes from an influenza B virus vaccine strain or isolate, e.g., one that is safe in humans, for instance, one that does not result in significant disease, that confer enhanced growth in cells in culture, such as MDCK cells, or in eggs. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/436245 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 2039/5258 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 2760/16023 (20130101) C12N 2760/16071 (20130101) C12N 2760/16221 (20130101) C12N 2760/16222 (20130101) C12N 2760/16234 (20130101) C12N 2760/16251 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197926 | Kawaoka et al. |
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| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin); The University of Tokyo (Tokyo, Japan) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (WARF) (Madison, Wisconsin); The University of Tokyo (Tokyo, Japan) |
| INVENTOR(S) | Yoshihiro Kawaoka (Middleton, Wisconsin); Shinya Yamada (Bunkyo-ku, Japan); Shiho Chiba (Madison, Wisconsin) |
| ABSTRACT | Modified influenza virus neuraminidases are described herein that improve viral replication, thus improving the yield of vaccine viruses. Expression of such modified neuraminidases by influenza virus may also stabilize co-expressed hemagglutinins so that the hemagglutinins do not undergo mutation. |
| FILED | Thursday, October 25, 2018 |
| APPL NO | 16/170321 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0043 (20130101) A61K 39/145 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/2402 (20130101) C12N 15/63 (20130101) C12N 2760/16021 (20130101) C12N 2760/16022 (20130101) C12N 2760/16034 (20130101) C12N 2760/16051 (20130101) Enzymes C12Y 302/01018 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197932 | Camacho et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kathryn M. Camacho (Los Angeles, California); Stefano Menegatti (Raleigh, North Carolina); Sunny Kumar (Aliso Viejo, California); Douglas Vogus (Goleta, California); Samir Mitragotri (Lexington, Massachusetts) |
| ABSTRACT | Pharmaceutical compositions comprising two or more therapeutically active agents, such as two or more anticancer agents, conjugated to one or more biocompatible polymers, wherein the molar ratio of the agents and/or schedules of delivery provide a synergistic therapeutic effect, are described. Methods of making and using the pharmaceutical compositions are further described. In one embodiment, the pharmaceutical compositions contain topoisomerase I and topoisomerase II inhibitors conjugated to the same or different biocompatible polymers. The two or more anticancer agents are covalently coupled to the polymer(s), and thereby can be delivered to a tumor at a molar ratio which provides a synergistic effect. Optionally, the agents are coupled indirectly to the polymer(s) via a linker. |
| FILED | Monday, April 13, 2020 |
| APPL NO | 16/846707 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 47/61 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197933 | Jenkins et al. |
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| FUNDED BY |
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| APPLICANT(S) | Elysium Therapeutics, Inc. (Akron, Ohio) |
| ASSIGNEE(S) | Elysium Therapeutics, Inc. (Akron, Ohio) |
| INVENTOR(S) | Thomas E. Jenkins (Half Moon Bay, California); Craig O. Husfeld (San Mateo, California) |
| ABSTRACT | The invention provides compositions and methods for the treatment or prevention of pain. Compositions provided are resistant to overdose and abuse. Compositions provided comprise two or more different molecules, where each molecule comprises at least one GI enzyme-labile opioid agonist releasing subunit comprising an opioid agonist that is covalently linked to at least one GI enzyme inhibitor subunit. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/572408 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) A61K 47/55 (20170801) A61K 47/64 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197934 | Rader et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Christoph Rader (Jupiter, Florida); Alex Nanna (Jupiter, Florida); William Roush (Jupiter, Florida) |
| ABSTRACT | Dual variable domain (DVD) immunoconjugates and uses thereof are provided. Aspects of the subject immunoconjugates include a DVD immunoglobulin molecule having a first and a second variable domain, and a cargo moiety (e.g., a drug moiety) that is covalently conjugated to the second variable domain via a linker. Methods of making and using the subject immunoconjugates in the prevention and/or treatment of cancer and other diseases are also provided. |
| FILED | Friday, September 16, 2016 |
| APPL NO | 15/760316 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/6803 (20170801) Original (OR) Class A61K 47/6849 (20170801) A61K 47/6851 (20170801) A61K 47/6855 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/28 (20130101) C07K 16/32 (20130101) C07K 16/2896 (20130101) C07K 2317/35 (20130101) C07K 2317/55 (20130101) C07K 2317/60 (20130101) C07K 2317/73 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197944 | Cezar et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); CHARITE UNIVERSITAETSMEDIZIN BERLIN (Berlin, Germany) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN (Berlin, Germany) |
| INVENTOR(S) | Christine A. Cezar (Cambridge, Massachusetts); Conor J. Walsh (Cambridge, Massachusetts); David J. Mooney (Sudbury, Massachusetts); Ellen T. Roche (Galway, Ireland); Herman H. Vandenburgh (Providence, Rhode Island); Georg N. Duda (Berlin, Germany) |
| ABSTRACT | The present invention provides methods and compositions for promoting regeneration of a tissue, methods for preventing or reducing inflammation of a tissue, methods for preventing or reducing fibrosis of a tissue, methods for increasing a mass of a tissue, methods for increasing a level of oxygen available to a tissue, methods for increasing a rate of metabolic waste removal from a tissue, methods for increasing blood perfusion to a tissue, and methods of treating severe muscle tissue damage in a subject in need thereof by contacting the tissue with a composition that is suitable for applying cyclic mechanical compression to the tissue. |
| FILED | Friday, November 18, 2016 |
| APPL NO | 15/776853 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/14 (20130101) A61L 27/042 (20130101) Original (OR) Class A61L 27/56 (20130101) A61L 2400/06 (20130101) A61L 2430/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197952 | Young et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advent Access Pte. Ltd. (Singapore, Singapore) |
| ASSIGNEE(S) | Advent Access Pte. Ltd. (Singapore, Singapore) |
| INVENTOR(S) | Nathaniel P. Young (Salt Lake City, Utah); Mark A. Crawford (Sandy, Utah) |
| ABSTRACT | A vascular access port can include a base that can be attached to a vessel and a body extending away from the base in at least a vertical direction. A height of the body in the vertical direction can be sufficiently small such that the entire port can be implanted subcutaneously in a patient. The port can include a guidance passageway that is at least partially defined by the body and can direct an access device into a vessel of a patient when the port is attached to the vessel. In some arrangements, the guidance passageway includes a funnel region that decreases in size from a proximal end of the guidance passageway toward a distal end of the guidance passageway that defines an opening through the bottom surface of the port. |
| FILED | Friday, April 19, 2019 |
| APPL NO | 16/389482 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0057 (20130101) A61B 17/3423 (20130101) A61B 2017/3425 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3653 (20130101) A61M 1/3659 (20140204) A61M 1/3661 (20140204) Original (OR) Class A61M 39/0208 (20130101) A61M 2205/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197955 | Doyle, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the Universitv of California (Oakland, California) |
| INVENTOR(S) | Francis J. Doyle, III (Santa Barbara, California); Eyal Dassau (Goleta, California); Dale E. Seborg (Santa Barbara, California); Joon Bok Lee (Santa Barbara, California) |
| ABSTRACT | A model-based control scheme consisting of either a proportional-integral-derivative (IMC-PID) controller or a model predictive controller (MPC), with an insulin feedback (IFB) scheme personalized based on a priori subject characteristics and comprising a lower order control-relevant model to obtain PID or MPC controller for artificial pancreas (AP) applications. |
| FILED | Tuesday, September 17, 2019 |
| APPL NO | 16/574076 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/022 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/1723 (20130101) Original (OR) Class A61M 2005/1726 (20130101) A61M 2205/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198127 | Sulchek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Todd Sulchek (Atlanta, Georgia); Alexander Alexeev (Atlanta, Georgia); Anna Liu (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present disclosure can include a method for convective intracellular delivery including providing cells and molecules to a microchannel having compressive surfaces, wherein the compressive surfaces define compression gaps having a height of from 20 and 80% of the average cell diameter; and a plurality of relaxation spaces disposed between the compressive surfaces; flowing the cell medium through the microchannel, wherein as the cell medium flows through the microchannel, the plurality of cells undergo a convective intracellular delivery process comprising: compressing the plurality of cells, wherein the compressing causes the plurality of cells to undergo a loss in intracellular volume (Vloss); and passing the plurality of cells to a first relaxation space, wherein the plurality of cells undergo a gain in volume (Vgain) and absorb a portion of the plurality of molecules. |
| FILED | Wednesday, November 08, 2017 |
| APPL NO | 16/348170 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2300/08 (20130101) B01L 2300/123 (20130101) B01L 2400/086 (20130101) B01L 2400/0463 (20130101) B01L 2400/0487 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 35/04 (20130101) C12M 47/04 (20130101) C12M 99/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/06 (20130101) C12N 15/87 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198135 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CIRCULOMICS INC. (Baltimore, Maryland) |
| ASSIGNEE(S) | Pacific Biosciences of California, Inc. (Menlo Park, California) |
| INVENTOR(S) | Kelvin Jeng-Fang Liu (Baltimore, Maryland); Jeffrey Michael Burke (Baltimore, Maryland) |
| ABSTRACT | Disclosed herein is a novel method to fabricate magnetic silica nanomembranes using thin polymer cores based on silica deposition and self-wrinkling induced by thermal shrinkage. These micro- and nano-scale structures have vastly enlarged the specific area of silica, thus the magnetic silica nanomembranes can be used for solid phase extraction of nucleic acids. The magnetic silica nanomembranes are suitable for nucleic acid purification and isolation and demonstrated better performance than commercial particles in terms of nucleic acid recovery yield and integrity. In addition, the magnetic silica nanomembranes may have high nucleic acid capacity due to significantly enlarged specific surface area of silica. Methods of use and devices comprising the magnetic silica nanomembranes are also provided herein. |
| FILED | Tuesday, June 30, 2020 |
| APPL NO | 16/917751 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 15/424 (20130101) Magnetic or Electrostatic Separation of Solid Materials From Solid Materials or Fluids; Separation by High-voltage Electric Fields B03C 1/01 (20130101) B03C 1/30 (20130101) Original (OR) Class B03C 1/286 (20130101) B03C 1/288 (20130101) B03C 2201/18 (20130101) B03C 2201/26 (20130101) Non-metallic Elements; Compounds Thereof; C01B 33/12 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 7/06 (20130101) C08J 2323/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1013 (20130101) C12N 15/1017 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/405 (20130101) G01N 35/0098 (20130101) G01N 35/0099 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198675 | Shen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Binghui Shen (La Verne, California); Judith Campbell (Pasadena, California); Li Zheng (Arcadia, California); Hongzhi Li (Duarte, California); David Horne (Duarte, California); Jun Xie (Duarte, California); Kenneth Karanja (Maple Grove, Minnesota) |
| ABSTRACT | Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2. |
| FILED | Monday, January 13, 2020 |
| APPL NO | 16/741559 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 215/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198678 | Rodriguez Pierluissi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Abimael D. Rodriguez Pierluissi (San Juan, Puerto Rico); Carlos Jimenez Romero (San Juan, Puerto Rico) |
| ASSIGNEE(S) | University of Puerto Rico (San Juan, Puerto Rico) |
| INVENTOR(S) | Abimael D. Rodriguez Pierluissi (San Juan, Puerto Rico); Carlos Jimenez Romero (San Juan, Puerto Rico) |
| ABSTRACT | Plakortinic acids A (2) and B (3), two polyketide endoperoxides having an unprecedented bicyclo[4.2.0]octene unit, were isolated as minor constituents from the sponge-sponge symbiotic association Plakortis halichondrioides-Xestospongia deweerdtae from Puerto Rico, along with the known epiplakinic acid F (1). The molecular structures of 2 and 3 were determined mainly on the basis of NMR spectroscopy. Due to the structural similarities, 2 and 3 are thought to be biosynthetically related to 1. Biological screening for cytotoxic activity against two human tumor cell lines revealed that these novel metabolites are very active at low to sub-micro molar concentration. |
| FILED | Tuesday, June 06, 2017 |
| APPL NO | 15/615788 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 317/04 (20130101) Original (OR) Class C07D 493/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198679 | Piazza et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ADT Pharmaceuticals, LLC (Orange Beach, Alabama) |
| ASSIGNEE(S) | ADT Pharmaceuticals, LLC (Orange Beach, Alabama) |
| INVENTOR(S) | Gary A. Piazza (Daphne, Alabama); Xi Chen (Hoover, Alabama); Adam B. Keeton (Gardendale, Alabama); Michael R. Boyd (Orange Beach, Alabama) |
| ABSTRACT | Disclosed are compounds, for example, a compound of formula I, wherein R, R0, R1-R8, n, X, Y, Y′, and E are as described herein, pharmaceutical compositions containing such compounds, and methods of treating or preventing a disease or condition for example, cancer, mediated by the ras gene. |
| FILED | Wednesday, April 01, 2020 |
| APPL NO | 16/837757 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/36 (20130101) A61K 31/36 (20130101) A61K 31/40 (20130101) A61K 31/40 (20130101) A61K 31/44 (20130101) A61K 31/44 (20130101) A61K 31/165 (20130101) A61K 31/165 (20130101) A61K 31/167 (20130101) A61K 31/216 (20130101) A61K 31/341 (20130101) A61K 31/341 (20130101) A61K 31/401 (20130101) A61K 31/421 (20130101) A61K 31/445 (20130101) A61K 31/445 (20130101) A61K 31/496 (20130101) A61K 31/4402 (20130101) A61K 31/4406 (20130101) A61K 31/5375 (20130101) A61K 31/5377 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) A61K 2800/00 (20130101) Acyclic or Carbocyclic Compounds C07C 233/58 (20130101) C07C 235/32 (20130101) C07C 235/34 (20130101) C07C 237/20 (20130101) C07C 311/29 (20130101) C07C 2601/02 (20170501) C07C 2602/08 (20170501) Heterocyclic Compounds C07D 207/14 (20130101) C07D 207/335 (20130101) C07D 207/337 (20130101) C07D 211/56 (20130101) C07D 213/24 (20130101) C07D 213/40 (20130101) C07D 213/75 (20130101) C07D 235/30 (20130101) C07D 307/38 (20130101) C07D 307/52 (20130101) C07D 307/54 (20130101) C07D 317/64 (20130101) Original (OR) Class C07D 405/12 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5748 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198682 | De Vivo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fondazione Istituto Italiano Di Tecnologia (Genoa, Italy); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | Fondazione Istituto Italiano Di Tecnologia (Genoa, Italy); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Marco De Vivo (Genoa, Italy); Anand Ganesan (Irvine, California); Jose Antonio Ortega Martinez (Genoa, Italy); Sohail Jahid (Irvine, California) |
| ABSTRACT | The present invention relates to compounds of Formula (I) or pharmaceutically acceptable salts or solvates thereof: It further discloses a pharmaceutical composition comprising the compounds of Formula (I) and their uses, in particular in the treatment of diseases or disorders associated to increased relative to physiological or desired RhoJ/Cdc42 levels of expression or function. |
| FILED | Wednesday, May 02, 2018 |
| APPL NO | 16/609720 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Heterocyclic Compounds C07D 401/14 (20130101) Original (OR) Class C07D 405/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198705 | Burke et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Martin D. Burke (Champaign, Illinois); Anuj Khandelwal (Salt Lake City, Utah); Jiabao Zhang (Urbana, Illinois); Anna SantaMaria (Rockville, Maryland) |
| ABSTRACT | Disclosed are derivatives of amphotericin B (AmB) characterized by improved clinical efficacy with reduced toxicity compared to AmB. Also disclosed are pharmaceutical compositions comprising the AmB derivatives, therapeutic methods of using the AmB derivatives and methods of making the AmB derivatives. |
| FILED | Friday, September 06, 2019 |
| APPL NO | 16/563243 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0053 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 17/00 (20130101) Original (OR) Class C07H 17/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198715 | Keating et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Amy Keating (Arlington, Massachusetts); Justin Michael Jenson (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are compounds comprising peptides that bind Bfl-1. Also provided are compositions containing these peptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the peptides. |
| FILED | Friday, July 21, 2017 |
| APPL NO | 16/319199 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 1/113 (20130101) C07K 14/00 (20130101) C07K 14/395 (20130101) C07K 14/4747 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/10 (20130101) C07K 2319/42 (20130101) C07K 2319/43 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) G01N 33/574 (20130101) G01N 2333/4703 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198717 | Mendoza et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Juan Luis Mendoza (Redwood City, California); Kenan Christopher Garcia (Menlo Park, California) |
| ABSTRACT | Compositions and methods are provided relating to Type III interferons. |
| FILED | Friday, September 29, 2017 |
| APPL NO | 16/336598 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) A61P 35/00 (20180101) Peptides C07K 14/555 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198723 | Branco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (New Orleans, Louisiana); THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California); THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas); ZALGEN LABS, LLC (Germantown, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Luis M. Branco (Germantown, Maryland); Robert F. Garry (New Orleans, Louisiana); James E. Robinson (New Orleans, Louisiana); Erica O. Saphire (La Jolla, California); Kathryn M. Hastie (La Jolla, California); Thomas W. Geisbert (Albany, Texas) |
| ABSTRACT | Disclosed herein are compositions comprising arenavirus monoclonal antibodies, as well as therapeutic, diagnostic, and preventative methods using the novel antibodies. Preventative methods include preparation of vaccines, as well as factors (e.g. small molecules, peptides) that inhibit Old World arenavirus infectivity, including LASV and LCMV. In some embodiments, the antibodies provide pan-arenavirus protection against a number of arenavirus types and strains. Diagnostic and therapeutic antibodies including neutralizing antibodies for the prevention and treatment of infection by LASV and other arenaviruses are also disclosed, as well as new tools and methods for the design, production, and use of arenavirus monoclonal antibodies, including expression in engineered bacterial- and mammalian-based systems. |
| FILED | Tuesday, December 05, 2017 |
| APPL NO | 16/466544 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/33 (20130101) C07K 2317/565 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2760/10011 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198724 | Nunez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan); Gabriel Nunez (Ann Arbor, Michigan); Jon Oscherwitz (Ann Arbor, Michigan); Kemp Cease (Ann Arbor, Michigan); Yumi Nakamura (Ann Arbor, Michigan); Tyler Nygaard (Bozeman, Montana) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Gabriel Nunez (Ann Arbor, Michigan); Jon Oscherwitz (Ann Arbor, Michigan); Kemp Cease (Ann Arbor, Michigan); Yumi Nakamura (Ann Arbor, Michigan); Tyler Nygaard (Bozeman, Montana) |
| ABSTRACT | Materials and methods are provided for treatment and/or prevention of Staphylococcal diseases and disorders such as infection and dermal inflammation. |
| FILED | Friday, March 14, 2014 |
| APPL NO | 14/774589 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/18 (20130101) A61K 31/37 (20130101) A61K 31/47 (20130101) A61K 31/192 (20130101) A61K 31/196 (20130101) A61K 31/235 (20130101) A61K 31/277 (20130101) A61K 31/366 (20130101) A61K 31/713 (20130101) A61K 39/40 (20130101) A61K 39/085 (20130101) A61K 45/06 (20130101) A61K 2039/505 (20130101) A61K 2039/575 (20130101) Peptides C07K 16/1271 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) C12N 2320/31 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198855 | Ha et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Taekjip Ha (Baltimore, Maryland); Sinan Arslan (Urbana, Illinois) |
| ABSTRACT | Conformationally-constrained helicases having improved activity and strength are provided. Methods of making conformationally-constrained helicases having improved activity and strength are provided. Methods of using conformationally-constrained helicases having improved activity and strength are provided. The present invention is based on the discovery of novel modified helicases that show dramatically enhanced helicase activity and increased strength as compared to unmodified helicases. As described further herein, it has been surprisingly discovered that, by controlling the conformation of certain subdomains such that the helicase remains in a closed form (e.g., by covalently crosslinking the 2B domain to the 1A domain or the 1B domain in a Rep helicase), a highly active and strong form of the helicase is achieved. |
| FILED | Friday, November 13, 2015 |
| APPL NO | 15/526905 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/14 (20130101) Original (OR) Class C12N 9/90 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Enzymes C12Y 306/04012 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198867 | Rigo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California); The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California); The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Frank Rigo (Carlsbad, California); C. Frank Bennett (Carlsbad, California); Constantin Van Outryve D'Ydewalle (Baltimore, Maryland); Charlotte J. Sumner (Baltimore, Maryland) |
| ABSTRACT | Certain embodiments are directed to methods and compounds for modulating expression of SMN. In certain embodiments at least two compounds are used: a first compound for inhibiting SMN-NAT and increasing expression of SMN, and a second compound for modulating the splicing of SMN. Such methods and compounds are useful for increasing expression exon 7 containing SMN mRNA in cells and animals. |
| FILED | Friday, June 16, 2017 |
| APPL NO | 16/307092 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) C12N 2310/322 (20130101) C12N 2310/3341 (20130101) C12N 2320/33 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198875 | Knecht et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| ASSIGNEE(S) | BRANDEIS UNIVERSITY (Waltham, Massachusetts) |
| INVENTOR(S) | Zachary Knecht (Waltham, Massachusetts); Paul Garrity (Waltham, Massachusetts); Lina Ni (Waltham, Massachusetts) |
| ABSTRACT | A method of modulating hygrosensing and/or thermosensing in an animal, particularly, an insect or disease vector, is provided. Also provided is a method of reducing survival, host-seeking, and/or reproductive capability of an animal, particularly an insect or disease vector. The methods involve an effective amount of an agent that modulates the activity and/or expression of a polynucleotide or polypeptide of an ionotropic receptor (Ir) selected from one or more of Ir25a, Ir93a, Ir40a, Ir68a, or Ir21a. A method of identifying an agent that modulates survival, host-seeking, and/or reproductive capability of an animal, e.g., an insect, is further provided. |
| FILED | Tuesday, May 09, 2017 |
| APPL NO | 16/099277 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/43581 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2800/80 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/68 (20130101) G01N 33/5085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198900 | Koussa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Mounir Ahmad Koussa (Somerville, Massachusetts); Kenneth Anders Halvorsen (Glenmont, New York); Andrew Ward (Boston, Massachusetts); Wesley Philip Wong (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides compositions comprising nucleic acid complexes for use in monitoring binding interactions and in measuring association and/or dissociation kinetics, detecting analytes including low concentration analytes, and screening library members. In some instances, the nucleic acid complexes are double-stranded nicked nucleic acids comprising a scaffold nucleic acid hybridized to one or more oligonucleotides. In some instances, a first, a second, a third, and optionally a fourth oligonucleotide are linked to moieties that are known to interact with each other or which are suspected of interacting with each other or of interacting with a common moiety such as an analyte. Changes in topology of the complex are used to determine the binding interactions of the various binding partners. |
| FILED | Monday, November 16, 2015 |
| APPL NO | 15/533473 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6818 (20130101) Original (OR) Class C12Q 1/6818 (20130101) C12Q 1/6818 (20130101) C12Q 2563/131 (20130101) C12Q 2563/131 (20130101) C12Q 2563/131 (20130101) C12Q 2565/125 (20130101) C12Q 2565/125 (20130101) C12Q 2565/133 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198907 | Salk et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Jesse Salk (Seattle, Washington); Lawrence A. Loeb (Bellevue, Washington); Michael Schmitt (Seattle, Washington) |
| ABSTRACT | Next Generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate hundreds of billions of nucleotides of DNA sequence in a single experiment, the error rate of approximately 1% results in hundreds of millions of sequencing mistakes. These scattered errors can be tolerated in some applications but become extremely problematic when “deep sequencing” genetically heterogeneous mixtures, such as tumors or mixed microbial populations. To overcome limitations in sequencing accuracy, a method Duplex Consensus Sequencing (DCS) is provided. This approach greatly reduces errors by independently tagging and sequencing each of the two strands of a DNA duplex. As the two strands are complementary, true mutations are found at the same position in both strands. In contrast, PCR or sequencing errors will result in errors in only one strand. This method uniquely capitalizes on the redundant information stored in double-stranded DNA, thus overcoming technical limitations of prior methods utilizing data from only one of the two strands. |
| FILED | Thursday, August 30, 2018 |
| APPL NO | 16/118306 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6806 (20130101) C12Q 1/6869 (20130101) C12Q 1/6869 (20130101) C12Q 1/6876 (20130101) Original (OR) Class C12Q 2525/179 (20130101) C12Q 2525/185 (20130101) C12Q 2525/191 (20130101) C12Q 2525/191 (20130101) C12Q 2535/119 (20130101) C12Q 2535/119 (20130101) C12Q 2535/122 (20130101) C12Q 2563/179 (20130101) C12Q 2565/514 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199543 | Fulkerson |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| ASSIGNEE(S) | Children's Hospital Medical Center (Cincinnati, Ohio) |
| INVENTOR(S) | Patricia C. Fulkerson (Cincinnati, Ohio) |
| ABSTRACT | Disclosed are methods of diagnosing and treating a subject with active or inactive eosinophilic esophagitis (EoE). The methods may include the steps of detecting whether a level of eosinophil lineage-committed progenitor (EoP) is elevated in a blood sample obtained from a subject, diagnosing the subject with active EoE when an EoP level in the sample is elevated above a pre-determined cut-off value and diagnosing the subject with inactive EoE when the EoP level in the sample is below a pre-determined cut-off value; and treating the subject diagnosed with active EoE. Kits related to same are also disclosed. |
| FILED | Wednesday, March 27, 2019 |
| APPL NO | 16/365740 |
| ART UNIT | 1611 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/20 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 33/56972 (20130101) Original (OR) Class G01N 2800/06 (20130101) G01N 2800/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200667 | Lay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Nathan S. Lay (Bethesda, Maryland); Yohannes Tsehay (Silver Spring, Maryland); Ronald M. Summers (Potomac, Maryland); Baris Turkbey (Rockville, Maryland); Matthew Greer (Bethesda, Maryland); Ruida Cheng (Bethesda, Maryland); Holger Roth (Bavaria, Germany); Matthew J. McAuliffe (Bethesda, Maryland); Sonia Gaur (Bethesda, Maryland); Francesca Mertan (Bethesda, Maryland); Peter Choyke (Rockville, Maryland) |
| ABSTRACT | Disclosed prostate computer aided diagnosis (CAD) systems employ a Random Forest classifier to detect prostate cancer. System classify individual pixels inside the prostate as potential sites of cancer using a combination of spatial, intensity and texture features extracted from three sequences. The Random Forest training considers instance-level weighting for equal treatment of small and large cancerous lesions and small and large prostate backgrounds. Two other approaches are based on an AutoContext pipeline intended to make better use of sequence-specific patterns. Also disclosed are methods and systems for accurate automatic segmentation of the prostate in MRI. Methods can include both patch-based and holistic (image-to-image) deep learning methods for segmentation of the prostate. A patch-based convolutional network aims to refine the prostate contour given an initialization. A method for end- to-end prostate segmentation integrates holistically nested edge detection with fully convolutional networks. HNNs automatically learn a hierarchical representation that improve prostate boundary detection. |
| FILED | Thursday, February 22, 2018 |
| APPL NO | 16/488127 |
| ART UNIT | 2647 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10088 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) G06T 2207/30081 (20130101) G06T 2207/30096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200672 | Cranmer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio); The Penn State Research Foundation (University Park, Pennsylvania); University of North Carolina (Chapel Hill, North Carolina); University of San Francisco (San Francisco, California) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio); The Penn State Research Foundation (University Park, Panama); University of North Carolina (Chapel Hill, North Carolina); University of San Francisco (San Francisco, California) |
| INVENTOR(S) | Skyler Cranmer (Columbus, Ohio); Bruce Desmarais (University Park, Pennsylvania); Shankar Bhamidi (Chapel Hill, North Carolina); James Wilson (San Francisco, California); Matthew Denny (University Park, Pennsylvania); Zhong-Lin Lu (Columbus, Ohio); Paul Stillman (Columbus, Ohio) |
| ABSTRACT | Systems and methods are described herein for modeling neural architecture. Regions of interest of a brain of a subject can be identified based on image data characterizing the brain of the subject. the identified regions of interest can be mapped to a connectivity matrix. The connectivity matrix can be a weighted and undirected network. A multivariate transformation can be applied to the connectivity matrix to transform the connectivity matrix into a partial correlation matrix. The multivariate transformation can maintain a positive definite constraint for the connectivity matrix. The partial correlation matrix can be transformed into a neural model indicative of the connectivity matrix. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/193911 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0263 (20130101) A61B 5/369 (20210101) A61B 5/4064 (20130101) A61B 5/7267 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) G01R 33/5608 (20130101) G01R 33/56341 (20130101) Electric Digital Data Processing G06F 17/16 (20130101) G06F 17/18 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6226 (20130101) Image Data Processing or Generation, in General G06T 7/0014 (20130101) Original (OR) Class G06T 2207/30016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11197769 | Sobinov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | West Virginia University (Morgantown, West Virginia); University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | West Virginia University (Morgantown, West Virginia); University of Pittsburgh Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Anton Sobinov (Morgantown, West Virginia); Sergiy Yakovenko (Morgantown, West Virginia); Valeriya Gritsenko (Morgantown, West Virginia); Matthew Boots (Morgantown, West Virginia); Robert Gaunt (Pittsburgh, Pennsylvania); Jennifer Collinger (Pittsburgh, Pennsylvania); Lee Fisher (Pittsburgh, Pennsylvania) |
| ABSTRACT | A system and method for controlling a device, such as a virtual reality (VR) and/or a prosthetic limb are provided. A biomimetic controller of the system comprises a signal processor and a musculoskeletal model. The signal processor processes M biological signals received from a residual limb to transform the M biological signals into N activation signals, where M and N are integers and M is less than N. The musculoskeletal model transforms the N activation signals into intended motion signals. A prosthesis controller transforms the intended motion signals into three or more control signals that are outputted from an output port of the prosthesis controller. A controlled device receives the control signals and performs one or more tasks in accordance with the control signals. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 16/722815 |
| ART UNIT | 2623 — Selective Visual Display Systems |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/389 (20210101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/70 (20130101) A61F 2/72 (20130101) Original (OR) Class A61F 2/582 (20130101) A61F 2002/704 (20130101) A61F 2002/0894 (20130101) A61F 2002/6827 (20130101) Electric Digital Data Processing G06F 3/011 (20130101) G06F 3/015 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197882 | Painter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | EMORY UNIVERSITY (Atlanta, Georgia) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia) |
| INVENTOR(S) | George R. Painter (Atlanta, Georgia); Gregory R. Bluemling (Decatur, Georgia); Michael G. Natchus (Alpharetta, Georgia); David Guthrie (Avondale Estates, Georgia) |
| ABSTRACT | This disclosure relates to certain N4-hydroxycytidine derivatives, pharmaceutical compositions, and methods related thereto. In certain embodiments, the disclosure relates to the treatment or prophylaxis of viral infections, such as Eastern, Western, and Venezuelan Equine Encephalitis (EEE, WEE and VEE, respectively), Chikungunya fever (CHIK), Ebola, Influenza, RSV, and Zika virus infection with the disclosed compounds. |
| FILED | Friday, December 07, 2018 |
| APPL NO | 16/755779 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7068 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 19/067 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197912 | Ma et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | TRIM-edicine, Inc. (Columbus, Ohio) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| INVENTOR(S) | Jianjie Ma (Powell, Ohio); Jacob S. Yount (Columbus, Ohio); Matthew A. Sermersheim (Nashville, Tennessee); Adam D. Kenney (Columbus, Ohio); Xinyu Zhou (Hilliard, Ohio); Bryan A. Whitson (Westerville, Ohio); Nahush A. Mokadam (Upper Arlington, Ohio); Tao Tan (Columbus, Ohio); Chuanxi Cai (Powell, Ohio) |
| ABSTRACT | Compositions for and methods of preventing, reversing or treating viral infection-induced organ failure provided. The compositions are also suitable for treating and/or preventing COVID-19 and influenza. The compositions and methods employ MG53, which can be in the form of recombinant human MG53. The MG53 may also be administered as a composition that expresses and releases MG53 after in vivo administration of said composition to a subject. |
| FILED | Thursday, February 25, 2021 |
| APPL NO | 17/184781 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198675 | Shen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | City of Hope (Duarte, California); California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | City of Hope (Duarte, California); California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Binghui Shen (La Verne, California); Judith Campbell (Pasadena, California); Li Zheng (Arcadia, California); Hongzhi Li (Duarte, California); David Horne (Duarte, California); Jun Xie (Duarte, California); Kenneth Karanja (Maple Grove, Minnesota) |
| ABSTRACT | Disclosed herein, inter alia, are compositions and methods for inhibiting DNA2. |
| FILED | Monday, January 13, 2020 |
| APPL NO | 16/741559 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/47 (20130101) A61K 45/06 (20130101) Heterocyclic Compounds C07D 215/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198923 | Giri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | U.S. Army Research Laboratory (Adelphi, Maryland) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Anit K. Giri (Abingdon, Maryland); Anthony J. Roberts (Chesapeake City, Maryland); Billy C. Hornbuckle (Aberdeen, Maryland); Scott M. Grendahl (Newark, Delaware); Kristopher A. Darling (Havre de Grace, Maryland) |
| ABSTRACT | Alloys comprised of a refined microstructure, ultrafine or nano scaled, that when reacted with water or any liquid containing water will spontaneously and rapidly produce hydrogen at ambient or elevated temperature are described. These metals, termed here as aluminum based nanogalvanic alloys will have applications that include but are not limited to energy generation on demand. The alloys may be composed of primarily aluminum and other metals e.g. tin bismuth, indium, gallium, lead, etc. and/or carbon, and mixtures and alloys thereof. The alloys may be processed by ball milling for the purpose of synthesizing powder feed stocks, in which each powder particle will have the above mentioned characteristics. These powders can be used in their inherent form or consolidated using commercially available techniques for the purpose of manufacturing useful functional components. |
| FILED | Monday, July 23, 2018 |
| APPL NO | 16/042632 |
| ART UNIT | 1732 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0018 (20130101) B22F 1/0044 (20130101) B22F 1/0044 (20130101) B22F 3/02 (20130101) B22F 9/04 (20130101) B22F 2009/043 (20130101) B22F 2009/043 (20130101) B22F 2207/13 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/08 (20130101) Alloys C22C 1/0416 (20130101) Original (OR) Class C22C 1/0416 (20130101) C22C 1/0416 (20130101) C22C 1/0483 (20130101) C22C 1/0483 (20130101) C22C 21/003 (20130101) C22C 21/08 (20130101) C22C 2200/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198927 | Chaput et al. |
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| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| INVENTOR(S) | Kevin J. Chaput (Beavercreek, Ohio); Oleg M. Senkov (Fairborn, Ohio); Todd M. Butler (Beavercreek, Ohio) |
| ABSTRACT | The present invention relates to Nb-based refractory alloys that are less expensive and less dense than some of the current Nb-based refractory alloys, have similar or better ductility, strength specific yield strength and oxidation resistance when compared to current Nb-based refractory alloys. Such Nb-based refractory alloys typically continue to be compatible with current coating systems for Nb-based refractory alloys. Such Nb-based refractory alloys are disclosed herein. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/583549 |
| ART UNIT | 1734 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Alloys C22C 27/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199099 | Crites et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| INVENTOR(S) | Daniel C. Crites (Mesa, Arizona); Michael Kahrs (Phoenix, Arizona); Brandan Wakefield (Phoenix, Arizona); Ardeshir Riahi (Scottsdale, Arizona) |
| ABSTRACT | An airfoil for a rotor blade in a gas turbine engine includes a first side wall and a second side wall joined to the first side wall at a leading edge and a trailing edge. The airfoil further includes a tip cap extending between the first and second side walls such that the tip cap and at least portions of the first and second side walls form a blade tip and an internal cooling system. The internal cooling system includes a leading edge cooling circuit, a central cooling circuit, and a trailing edge cooling circuit. Each of the internal passages within the leading edge cooling circuit, the central cooling circuit, and the trailing edge cooling circuit is bounded in the radial outward direction with a surface that has at least one escape hole or that is positively angled in the radial outward direction relative to a chordwise axis. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 16/826953 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 5/186 (20130101) F01D 5/187 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2230/50 (20130101) F05D 2240/30 (20130101) F05D 2240/307 (20130101) F05D 2260/201 (20130101) F05D 2260/202 (20130101) F05D 2260/607 (20130101) F05D 2260/2212 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199103 | Wolfer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | General Electric Company (Schenectady, New York) |
| INVENTOR(S) | Scott Francis Wolfer (Cincinnati, Ohio); Kevin Richard Crain (Wakefield, Massachusetts); Jonathan K. Remer (Saugus, Massachusetts); Robert Burton Brown (Medford, Massachusetts); Nicholas Rowe Dinsmore (Marblehead, Massachusetts) |
| ABSTRACT | A seal assembly for a turbomachine. The turbomachine includes a rotating shaft extending along a centerline and a fixed housing positioned exterior to the rotating shaft in a radial direction relative to the centerline. The seal assembly includes a sump housing at least partially defining a bearing compartment for holding a cooling lubricant. The seal assembly further includes a bearing supporting the rotating shaft. In addition, the seal assembly also includes a sump seal at least partially defining the bearing compartment. A pressurized housing of the seal assembly is positioned exterior to the sump housing and defines a pressurized compartment to at least partially enclose the sump housing. Further, a non-contacting carbon seal is positioned between the rotating shaft and the fixed housing to at least partially define the pressurized compartment to enclose the sump housing. |
| FILED | Thursday, September 06, 2018 |
| APPL NO | 16/123572 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/04 (20130101) Original (OR) Class F01D 25/125 (20130101) F01D 25/183 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/52 (20130101) F05D 2240/54 (20130101) F05D 2240/56 (20130101) F05D 2260/20 (20130101) F05D 2260/98 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199106 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | Yiwei Jiang (Rockford, Illinois); Michael D. Schelonka (Elgin, Illinois); Erik D. LeBeau (West Dundee, Illinois) |
| ABSTRACT | A shroud having an annular member extending along an axis from a first end to a second end. The annular member has an inside surface radially inward from an outside surface that diverges from the first end towards the second end relative to the axis. The shroud further includes a flange that extends radially outward from the outside surface and a recess, each located at the second end. The recess extends radially outward from the inside surface and circumferentially about the axis. An axial extent of the recess at least partially coincides with an axial extent of the flange. |
| FILED | Friday, August 21, 2020 |
| APPL NO | 16/999497 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 11/08 (20130101) F01D 11/122 (20130101) F01D 21/045 (20130101) Original (OR) Class Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/055 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/323 (20130101) F05D 2240/14 (20130101) F05D 2260/607 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199134 | Shipley, Jr. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United Technologies Corporation (Farmington, Connecticut) |
| ASSIGNEE(S) | Ford Global Technologies, LLC (Dearborn, Michigan) |
| INVENTOR(S) | Edward Nicholas Shipley, Jr. (Vernon, Connecticut) |
| ABSTRACT | A gas turbine engine has an engine core including a primary flowpath. A first bypass duct is positioned radially outward of the engine core. A gas discharge protrudes radially into the first bypass duct. The gas discharge includes a fairing defining a lobed outlet. The lobed outlet includes a plurality of axially aligned peaks and axially aligned valleys. Each of the axially aligned valleys is configured to prevent a fluid passing through the valley from traveling radially inward immediately downstream of the fairing creating regions of relatively cool, mixed, and hot airflows. |
| FILED | Friday, August 11, 2017 |
| APPL NO | 15/674824 |
| ART UNIT | 3741 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/14 (20130101) F02C 7/185 (20130101) Original (OR) Class Jet-propulsion Plants F02K 3/077 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/213 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199343 | Chester et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mainstream Engineering Corporation (Rockledge, Florida) |
| ASSIGNEE(S) | Mainstream Engineering Corporation (Rockledge, Florida) |
| INVENTOR(S) | Gregory E. Chester (Rockledge, Florida); Ryan D. Reeves (Melbourne, Florida); Justin J. Hill (Rockledge, Florida) |
| ABSTRACT | A process is disclosed for cooling a material that includes semiconductor nanoparticles in matrix material by anti-Stokes up-conversion. The semiconductor nanoparticle matrix is irradiated by a laser with a photonic wavelength matched to the anti-Stokes photoluminescence of the semiconductor nanoparticle bandgap. The semiconductor nanoparticles absorb the laser photon and phonons (heat) from lattice vibrations to photoluminescence photons with higher energy than the photon that were absorbed. A net cooling effect is generated from the lower energy and lower temperature in the material after anti-Stoke up-conversion. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/583366 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 23/003 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/262 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199382 | Bride et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | United States of America as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Dustin Bride (Panama City Beach, Florida); Patrick Delay (Panama City Beach, Florida); Jeremy Croom (Panama City Beach, Florida); Bobbi Wood (Panama City Beach, Florida); Daniel Coats (Panama, Florida) |
| ABSTRACT | A mine roller includes a bracket having a first end and a second end. The first end is adapted to be coupled to a vehicle. A rigid table has a center section and modular sections with the center section being coupled to the second end of the bracket for rotation about the second end in a first plane. The modular sections are coupled to the center section for rotation therewith. Roller banks are coupled to two of the modular sections for rotation relative thereto in a second plane that is perpendicular to the first plane. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/887292 |
| ART UNIT | 3641 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Armour; Armoured Turrets; Armoured or Armed Vehicles; Means of Attack or Defence, e.g Camouflage, in General F41H 11/30 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199449 | Fontenot et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Ross S. Fontenot (Montgomery Village, Maryland); John H. Barkyoumb (Kensington, Maryland); Veerendra K. Mathur (Beltsville, Maryland) |
| ABSTRACT | According to exemplary practice of the present invention, a probe laser beam characterized by a Stokes luminescence wavelength is trained upon a thermally insulated medium; the Stokes luminescence is measured upon conclusion of the probe laser impingement of the medium. Following this first Stokes luminescence measurement, a pump laser beam characterized by an anti-Stokes luminescence wavelength is trained upon the medium; the Stokes luminescence is measured upon conclusion of the pump laser impingement of the medium. Each laser has a blocking device associated therewith. A computer is implemented to transmit control signals to open and close the two blocking devices in alternating fashion so that only one laser beam at a time is aimed at the medium. The computer is also implemented to process the measurement signals to determine heating versus cooling. If the luminescence intensity following the pump laser impingement exceeds the luminescence intensity following the probe laser impingement, then the medium is being cooled. |
| FILED | Friday, September 20, 2019 |
| APPL NO | 16/578136 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/4406 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/64 (20130101) G01N 21/636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199462 | Sotoudeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intelligent Fiber Optic Systems, Inc. (San Jose, California) |
| ASSIGNEE(S) | Intelligent Fiber Optic Systems, Inc. (San Jose, California) |
| INVENTOR(S) | Vahid Sotoudeh (Los Altos, California); Behzad Moslehi (Los Altos, California); Joshua Kuehn (Boulder Creek, California); Richard J. Black (Menlo Park, California) |
| ABSTRACT | A temperature correcting pressure gauge which has a diaphragm having at least one surface coupled to a source of pressure to be measured, the diaphragm first surface having a first FBG from a first optical fiber attached in an appropriately sensitive region of the diaphragm, a FBG from a second optical fiber attached to the opposite surface from the first FBG, the first and second FBGs reflecting or transmitting optical energy of decreasing or increasing wavelength, respectively, in response to an applied pressure. The first and second FBGs have nominal operating wavelength ranges that are adjacent to each other but are exclusive ranges and the FBGs also have closely matched pressure coefficients and temperature coefficients. |
| FILED | Wednesday, December 11, 2019 |
| APPL NO | 16/709936 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/246 (20130101) G01L 11/025 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/0218 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199476 | Tison et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LUNA INNOVATIONS INCORPORATED (Roanoke, Virginia) |
| ASSIGNEE(S) | LUNA INNOVATIONS INCORPORATED (Roanoke, Virginia) |
| INVENTOR(S) | Christopher K. Tison (Roanoke, Virginia); Blaine Butler (Roanoke, Virginia); Matthew Patterson (Roanoke, Virginia); Nikolai Braun (Roanoke, Virginia) |
| ABSTRACT | Biological specimen recovery materials include cellulose acetate nanofibers that are capable of dissolution upon contact with a liquid comprising a dissolution effective amount (e.g., between about 1 to about 10M) guanidinium isothiocyanate (GITC). Kits containing the materials (e.g., in the form of a swab, filtration media or surface wipe) and a dissolution liquid containing the dissolution effective amount of guanidinium isothiocyanate (GITC) are also provided. |
| FILED | Thursday, December 21, 2017 |
| APPL NO | 16/470668 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/24 (20130101) C12Q 1/6806 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) Original (OR) Class G01N 1/4055 (20130101) G01N 2001/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199587 | McQuellon et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Conner B. McQuellon (Bloomington, Indiana); Jeffrey D. Weddle (Trafalgar, Indiana); Julie D. Doerge (Ozark, Illinois); Reeve A. Arce (Bedford, Indiana) |
| ABSTRACT | The present invention relates to a swinging door test system that can test the accuracy of a balanced magnetic switch installed on a mock door. An actuator opens and closes a door to change the magnetic switch state. Software implementation allows the actuator to be precisely controlled over many cycles to save time and effort. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 16/811058 |
| ART UNIT | 2858 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/52 (20200101) G01R 31/3277 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199649 | Morgan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Crane, Indiana) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Timothy Allen Morgan (Ellettsville, Indiana); Benjamin R. Conley (Bloomington, Indiana) |
| ABSTRACT | The present invention relates to a metamaterial focal plane array for broad spectrum imaging. Electromagnetic energy in the form of light is absorbed in or on a metamaterial absorber and a subsequent hot carriers are collected either in a semiconductor space charge region (e.g. P-N junction), or in some other modern collection scheme. Following the accumulation of photogenerated charge (electrons or holes), the signal is then converted to a digital signal using conventional or slightly modified ROIC modules. |
| FILED | Thursday, August 20, 2020 |
| APPL NO | 16/997994 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 5/20 (20130101) G01J 5/0853 (20130101) G01J 2005/202 (20130101) Optical Elements, Systems, or Apparatus G02B 1/002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200035 | Baskaran et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Reservoir Labs, Inc. (New York, New York) |
| ASSIGNEE(S) | Reservoir Labs, Inc. (New York, New York) |
| INVENTOR(S) | Muthu M. Baskaran (Old Tappan, New Jersey); Richard A. Lethin (New York, New York); Benoit J. Meister (New York, New York); Nicolas T. Vasilache (New York, New York) |
| ABSTRACT | Methods, apparatus and computer software product for source code optimization are provided. In an exemplary embodiment, a first custom computing apparatus is used to optimize the execution of source code on a second computing apparatus. In this embodiment, the first custom computing apparatus contains a memory, a storage medium and at least one processor with at least one multi-stage execution unit. The second computing apparatus contains at least one local memory unit that allows for data reuse opportunities. The first custom computing apparatus optimizes the code for reduced communication execution on the second computing apparatus. |
| FILED | Monday, November 27, 2017 |
| APPL NO | 15/822996 |
| ART UNIT | 2192 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 8/41 (20130101) Original (OR) Class G06F 8/453 (20130101) G06F 8/457 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200175 | Boettcher |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arm Limited (Cambridge, United Kingdom) |
| ASSIGNEE(S) | Arm Limited (Cambridge, United Kingdom) |
| INVENTOR(S) | Matthias Lothar Boettcher (Cambridge, United Kingdom) |
| ABSTRACT | There is provided a data processing apparatus that includes memory circuitry that provides a physical address space, which is logically divided into a plurality of memory segments and stores a plurality of accessors with associated validity indicators. Each of the accessors controls access to a region of the physical address space in dependence on at least its associated validity indicator. Tracking circuitry tracks which of the memory segments contain the accessors and invalidation circuitry responds to a request to invalidate an accessor by determining a set of equivalent accessors with reference to the tracking circuitry, and invalidating the accessor and the equivalent accessors by setting the associated validity indicator of each of the accessor and the equivalent accessors to indicate that the accessor and the equivalent accessors are invalid. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 16/825021 |
| ART UNIT | 2139 — Memory Access and Control |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30018 (20130101) G06F 12/023 (20130101) G06F 12/0864 (20130101) G06F 12/0891 (20130101) Original (OR) Class G06F 12/1027 (20130101) G06F 12/1458 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200186 | Fleming, Jr. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kermin E. Fleming, Jr. (Hudson, Massachusetts); Simon C. Steely, Jr. (Hudson, New Hampshire); Kent D. Glossop (Nashua, New Hampshire); Mitchell Diamond (Shrewsbury, Massachusetts); Benjamin Keen (Marlborough, Massachusetts); Dennis Bradford (Portland, Oregon); Fabrizio Petrini (Menlo Park, California); Barry Tannenbaum (Nashua, New Hampshire); Yongzhi Zhang (Wayland, Massachusetts) |
| ABSTRACT | Systems, methods, and apparatuses relating to operations in a configurable spatial accelerator are described. In one embodiment, a configurable spatial accelerator includes a first processing element that includes a configuration register within the first processing element to store a configuration value that causes the first processing element to perform an operation according to the configuration value, a plurality of input queues, an input controller to control enqueue and dequeue of values into the plurality of input queues according to the configuration value, a plurality of output queues, and an output controller to control enqueue and dequeue of values into the plurality of output queues according to the configuration value. |
| FILED | Saturday, June 30, 2018 |
| APPL NO | 16/024854 |
| ART UNIT | 2185 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30145 (20130101) G06F 13/4027 (20130101) Original (OR) Class G06F 15/7867 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200257 | McQueary et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Securboration, Inc. (Melbourne, Florida) |
| ASSIGNEE(S) | Securboration, Inc. (Melbourne, Florida) |
| INVENTOR(S) | Bruce R. McQueary (Indialantic, Florida); Craig T. Hagan (Melbourne Beach, Florida); Robert G. Asfar (Sebastian, Florida) |
| ABSTRACT | Methods and systems for classifying social media users. The system computes a plurality of subgraphs from a user's social graph network and considers which types of subgraphs are overly represented in the user's social network to determine whether a user belongs to a certain class. The system may also consider features based on metadata of the user's network and social interactions occurring in the user's network. |
| FILED | Tuesday, April 25, 2017 |
| APPL NO | 15/496328 |
| ART UNIT | 2153 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 16/285 (20190101) Original (OR) Class G06F 16/9024 (20190101) G06F 16/9535 (20190101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) G06N 20/00 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200418 | Bushmitch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Dennis Bushmitch (Somerset, New Jersey); Michael Badger (Ocean Grove, New Jersey) |
| ABSTRACT | Various embodiments associated with a composite image are described. In one embodiment, a handheld device comprises a launch component configured to cause a launch of a projectile. The projectile is configured to capture a plurality of images. Individual images of the plurality of images are of different segments of an area. The system also comprises an image stitch component configured to stitch the plurality of images into a composite image. The composite image is of a higher resolution than a resolution of individual images of the plurality of images. |
| FILED | Friday, September 23, 2016 |
| APPL NO | 15/274060 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/08 (20130101) B64C 2201/123 (20130101) B64C 2201/127 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) Original (OR) Class G06K 9/00771 (20130101) G06K 2009/2045 (20130101) Image Data Processing or Generation, in General G06T 3/4038 (20130101) G06T 3/4053 (20130101) G06T 5/50 (20130101) G06T 7/33 (20170101) G06T 7/38 (20170101) G06T 11/60 (20130101) G06T 2207/10032 (20130101) G06T 2207/20221 (20130101) G06T 2207/30181 (20130101) G06T 2207/30212 (20130101) Pictorial Communication, e.g Television H04N 5/28 (20130101) H04N 5/2624 (20130101) H04N 5/23238 (20130101) H04N 5/23293 (20130101) H04N 7/185 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200474 | Swager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy M. Swager (Newton, Massachusetts); Joseph Michael Azzarelli (Cambridge, Massachusetts); Rong Zhu (Waltham, Massachusetts) |
| ABSTRACT | A wireless sensor platform design and a single walled carbon nanotube/ionic liquid-based chemidosimeter system can incorporated into a highly sensitive and selective chemical hazard badge that can dosimetrically detect an analyte down to a sub parts-per-million concentration. |
| FILED | Tuesday, December 31, 2019 |
| APPL NO | 16/732095 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/082 (20130101) A61B 5/4845 (20130101) A61B 2562/029 (20130101) A61B 2562/0285 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/122 (20130101) G01N 27/127 (20130101) G01N 27/4146 (20130101) G01N 33/0057 (20130101) G01N 33/0075 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/0717 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200496 | Arthur et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | John V. Arthur (Mountain View, California); Pallab Datta (San Jose, California); Steven K. Esser (San Jose, California); Myron D. Flickner (San Jose, California); Dharmendra S. Modha (San Jose, California); Tapan K. Nayak (San Jose, California) |
| ABSTRACT | Hardware placement of neural networks is provided. In various embodiments, a network description is read. The network description describes a spiking neural network. The neural network is trained. An initial placement of the neural network on a plurality of cores is performed. The cores are located on a plurality of chips. Inter-chip communications are measured based on the initial placement. A final placement of the neural network on the plurality of cores is performed based on the inter-chip communications measurements and the initial placement. The final placement reduces inter-chip communication. |
| FILED | Tuesday, October 24, 2017 |
| APPL NO | 15/792155 |
| ART UNIT | 2127 — AI & Simulation/Modeling |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/049 (20130101) G06N 3/063 (20130101) G06N 3/082 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200691 | Javidi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | UNIVERSITY OF CONNECTICUT (Farmington, Connecticut) |
| INVENTOR(S) | Bahram Javidi (Storrs, Connecticut); Satoru Komatsu (Kanagawa, Japan); Adam Markman (Orange, Connecticut) |
| ABSTRACT | Systems and methods for optical sensing, visualization and detection in media (e.g., turbid media; turbid water; fog; non-turbid media). A light source and an image sensor are positioned in turbid media or external to the turbid media with the light source within a field of view of the image sensor array. Temporal optical signals are transmitted through the turbid media via the light source and multiple perspective video sequence frames are acquired via the image sensor array of light propagating through the turbid media. A three-dimensional image is reconstructed from each frame and the reconstructed three-dimensional images are combined to form a three-dimensional video sequence. The transmitted optical signals are detected from the three-dimensional video sequence by applying a multi-dimensional signal detection scheme. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/887843 |
| ART UNIT | 2669 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/0063 (20130101) G06K 9/00758 (20130101) Image Data Processing or Generation, in General G06T 7/97 (20170101) G06T 7/521 (20170101) G06T 7/536 (20170101) G06T 7/557 (20170101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200947 | Berggren et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Karl K. Berggren (Arlington, Massachusetts); Oguzhan Murat Onen (Boston, Massachusetts); Brenden Butters (Cambridge, Massachusetts); Emily Toomey (Cambridge, Massachusetts) |
| ABSTRACT | Apparatus and methods relating to programmable superconducting cells are described. A programmable superconducting cell can be formed from a superconducting current loop having at least two terminals connected to the loop. The current loop and terminals can be formed from a single layer of superconducting material. The programmable superconducting cell can be incorporated into a crossbar architecture to form a high-speed vector-matrix multiplying processor for deep neural network computations. |
| FILED | Monday, February 04, 2019 |
| APPL NO | 16/266507 |
| ART UNIT | 2824 — Semiconductors/Memory |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) Static Stores G11C 5/025 (20130101) G11C 11/44 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/10 (20130101) H01L 39/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201028 | Lagally et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Regents of the University of New Mexico (Albuquerque, New Mexico) |
| INVENTOR(S) | Max G. Lagally (Madison, Wisconsin); Matthew McLean Dwyer (Madison, Wisconsin); Francesca Cavallo (Albuquerque, New Mexico); Daniel Warren van der Weide (Madison, Washington); Abhishek Bhat (Madison, Wisconsin) |
| ABSTRACT | Traveling-wave tube amplifiers for high-frequency signals, including terahertz signals, and methods for making a slow-wave structure for the traveling-wave tube amplifiers are provided. The slow-wave structures include helical conductors that are self-assembled via the release and relaxation of strained films from a sacrificial growth substrate. |
| FILED | Tuesday, October 01, 2019 |
| APPL NO | 16/589348 |
| ART UNIT | 2843 — Semiconductors/Memory |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 9/14 (20130101) H01J 23/24 (20130101) H01J 23/26 (20130101) Original (OR) Class H01J 25/34 (20130101) H01J 25/44 (20130101) H01J 2209/012 (20130101) Amplifiers H03F 3/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201058 | Anderson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | Travis J. Anderson (Alexandria, Virginia); James C. Gallagher (Alexandria, Virginia); Marko J. Tadjer (Vienna, Virginia); Alan G. Jacobs (Arlington, Virginia); Boris N. Feigelson (Springfield, Virginia) |
| ABSTRACT | A method for activating implanted dopants and repairing damage to dopant-implanted GaN to form n-type or p-type GaN. A GaN substrate is implanted with n- or p-type ions and is subjected to a high-temperature anneal to activate the implanted dopants and to produce planar n- or p-type doped areas within the GaN having an activated dopant concentration of about 1018-1022 cm−3. An initial annealing at a temperature at which the GaN is stable at a predetermined process temperature for a predetermined time can be conducted before the high-temperature anneal. A thermally stable cap can be applied to the GaN substrate to suppress nitrogen evolution from the GaN surface during the high-temperature annealing step. The high-temperature annealing can be conducted under N2 pressure to increase the stability of the GaN. The annealing can be conducted using laser annealing or rapid thermal annealing (RTA). |
| FILED | Monday, July 13, 2020 |
| APPL NO | 16/927061 |
| ART UNIT | 2893 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/266 (20130101) H01L 21/3245 (20130101) H01L 21/26546 (20130101) Original (OR) Class H01L 21/28575 (20130101) H01L 29/36 (20130101) H01L 29/207 (20130101) H01L 29/452 (20130101) H01L 29/2003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201285 | Fang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Nicholas Fang (Lexington, Massachusetts); Zheng Jie Tan (Cambridge, Massachusetts) |
| ABSTRACT | The techniques described herein relate to methods and apparatus for a resistive switching device. The resistive switching device includes a first electrode formed in a substrate. The resistive switching device also includes a plurality of layers formed above the first electrode, including a plurality of oxide layers, wherein one or more of the plurality of oxide layers comprise doped oxide layers, and one or more conductive spacers, wherein each pair of oxide layers of the plurality of oxide layers are separated by a conductive spacer of the one or more conductive spacers. The resistive switching device also includes a second electrode formed above the plurality of layers, such that the first electrode, the plurality of layers, and the second electrode are in series. |
| FILED | Friday, March 06, 2020 |
| APPL NO | 16/812082 |
| ART UNIT | 2814 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 45/08 (20130101) H01L 45/146 (20130101) Original (OR) Class H01L 45/1233 (20130101) H01L 45/1253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201530 | Fei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Fan Fei (West Lafayette, Indiana); Xinyan Deng (West Lafayette, Indiana) |
| ABSTRACT | Disclosed herein are permanent magnetic AC machine direct-drive resonant flapper system for flapping wing micro air vehicles and flapping fin autonomous underwater vehicles. |
| FILED | Tuesday, May 29, 2018 |
| APPL NO | 15/992002 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Offensive or Defensive Arrangements on Vessels; Mine-laying; Mine-sweeping; Submarines; Aircraft Carriers B63G 8/08 (20130101) B63G 2008/002 (20130101) Marine Propulsion or Steering B63H 1/04 (20130101) B63H 1/36 (20130101) Dynamo-electric Machines H02K 1/17 (20130101) H02K 1/22 (20130101) H02K 7/065 (20130101) H02K 33/06 (20130101) H02K 33/16 (20130101) H02K 33/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201627 | Murphy |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Robert J. Murphy (Westwood, Massachusetts) |
| ABSTRACT | Spectrally-efficient digital logic (SEDL) techniques implement spectrally-efficient pulses (e.g., Gaussian-shaped pulses) in lieu of conventional square waveforms to improve electromagnetic, radio frequency, and other unwanted emissions. The SEDL techniques can be used for analog-to-digital converters (ADC) and digital-to-analog converters (DAC). An ADC circuit comprises a plurality of comparators configured to receive an analog input signal and compare the analog input signal to a predetermined reference signal, an encoder, and a spectrally-efficient circuit. A DAC circuit includes an integrator circuit, a clocked comparator circuit, a pulse generator, and a combiner circuit. The clocked comparator circuit receives the logic state of each SEDL pulse. The pulse generator receives the logic state and generates a scaled SEDL pulse for each input SEDL pulse. A combiner circuit combines the outputs from the pulse generator and determines analog value corresponding to the input values. |
| FILED | Thursday, August 22, 2019 |
| APPL NO | 16/548091 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Pulse Technique H03K 5/2427 (20130101) H03K 19/20 (20130101) H03K 19/21 (20130101) Coding; Decoding; Code Conversion in General H03M 1/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11197854 | Kent et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Michael S. Kent (Albuquerque, New Mexico); Susan Rempe (Albuquerque, New Mexico); Juan M. Vanegas (Burlington, Vermont) |
| ABSTRACT | The present invention relates to methods for identifying candidate therapeutics for a disease caused by a viral envelope protein. In particular, the method can include contacting a test envelope protein with the candidate and determining its activity. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 16/684445 |
| ART UNIT | 1629 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/12 (20130101) A61K 31/121 (20130101) A61K 31/122 (20130101) A61K 31/201 (20130101) A61K 31/351 (20130101) A61K 31/366 (20130101) A61K 31/4745 (20130101) Original (OR) Class A61K 31/7032 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197938 | O'Hara |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Matthew J. O'Hara (Richland, Washington) |
| ABSTRACT | Methods for purifying 89Zr are provided, 89Zr compositions are provided, isotope compositions are provided that can include: a radio isotope and a nanoparticle, and methods for radio labeling monoclonal antibodies are provided. |
| FILED | Thursday, October 19, 2017 |
| APPL NO | 15/788724 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/10 (20130101) Original (OR) Class Separation B01D 59/30 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 25/003 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/20 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/001 (20130101) G21G 4/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198101 | Newbloom et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Membrion, Inc. (Seattle, Washington) |
| ASSIGNEE(S) | Membrion, Inc. (Seattle, Washington) |
| INVENTOR(S) | Gregory Matthew Newbloom (Seattle, Washington); Olivia Marie Lenz (Seattle, Washington); Phillip Reaves Pickett (Bainbridge Island, Washington); Rachel Alexis Malone (Seattle, Washington); Stephanie Lynn Candelaria (Seattle, Washington); Yiheng Zhang (Seattle, Washington); Kathryn Lynn Corp (Seattle, Washington); Aditya Ashok Salunkhe (Seattle, Washington); Matthew Jason Canin (Kirkland, Washington) |
| ABSTRACT | Cation exchange membranes and materials including silica-based ceramics, and associated methods, are provided. In some aspects, cation exchange membranes that include a silica-based ceramic that forms a coating on and/or within a porous support membrane are described. The cation exchange membranes and materials may have certain structural or chemical attributes (e.g., pore size/distribution, chemical functionalization) that, alone or in combination, can result in advantageous performance characteristics in any of a variety of applications for which selective transport of positively charged ions through membranes/materials is desired. In some embodiments, the silica-based ceramic contains relatively small pores (e.g., substantially spherical nanopores) that may contribute to some such advantageous properties. In some embodiments, the cation exchange membrane or material includes sulfonate and/or sulfonic acid groups covalently bound to the silica-based ceramic. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244170 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 67/0093 (20130101) B01D 69/10 (20130101) B01D 69/148 (20130101) Original (OR) Class B01D 71/027 (20130101) B01D 71/66 (20130101) B01D 71/70 (20130101) B01D 71/78 (20130101) B01D 71/82 (20130101) B01D 2313/40 (20130101) B01D 2323/36 (20130101) B01D 2325/02 (20130101) B01D 2325/12 (20130101) B01D 2325/14 (20130101) B01D 2325/42 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/23 (20210101) C25B 13/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198109 | Bai et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ExxonMobil Research and Engineering Company (Annandale, New Jersey); TDA Research, Inc. (Wheat Ridge, Colorado) |
| ASSIGNEE(S) | ExxonMobil Research and Engineering Company (Annandale, New Jersey); TDA Research, Inc. (Wheat Ridge, Colorado) |
| INVENTOR(S) | Chuansheng Bai (Phillipsburg, New Jersey); Majosefina Cunningham (Whitehall, Pennsylvania); Patrick P. McCall (Matawan, New Jersey); Hans Thomann (Bedminster, New Jersey); Jeannine Elizabeth Elliott (Superior, Colorado); Vinh Nguyen (Arvada, Colorado) |
| ABSTRACT | The disclosure generally relates to CCS sorbents, particularly for CO2/H2O displacement desorption process. The sorbents include an aluminum oxide support that includes two alkali metal salts impregnated on the support. The two alkali metals include a potassium metal salts and a second alkali metal salt which is not potassium. The second metal salt disrupts poisoning effects that degrade sorbent lifetime. The sorbents demonstrate improved CO2 loadings and better H2O/CO2 ratios, as well as improved stability. Compositions and methods of making are disclosed. |
| FILED | Friday, March 02, 2018 |
| APPL NO | 15/910159 |
| ART UNIT | 1731 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 53/0462 (20130101) B01D 2253/25 (20130101) B01D 2253/1124 (20130101) B01D 2257/504 (20130101) B01D 2258/0283 (20130101) B01D 2259/40086 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/08 (20130101) B01J 20/041 (20130101) Original (OR) Class B01J 20/3078 (20130101) B01J 20/3204 (20130101) B01J 20/3236 (20130101) B01J 20/3433 (20130101) B01J 20/3466 (20130101) Capture, Storage, Sequestration or Disposal of Greenhouse Gases [GHG] Y02C 20/40 (20200801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198153 | Xu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PPG Industries Ohio, Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiangling Xu (Pittsburgh, Pennsylvania); Richard J. Sadvary (Tarentum, Pennsylvania); Shanti Swarup (Allison Park, Pennsylvania); Hongying Zhou (Allison Park, Pennsylvania) |
| ABSTRACT | A multi-layer coating includes: a first basecoat layer applied over at least a portion of a substrate; and a second basecoat layer applied over the first basecoat layer. The first basecoat layer and second basecoat layer are formed from compositions having a polyhydrazide and core-shell particles dispersed in aqueous mediums. The core-shell particles of the first basecoat composition includes (1) a polymeric core at least partially encapsulated by (2) a polymeric shell comprising urea linkages, and keto and/or aldo functional groups. The polymeric core of the core-shell particles of the first basecoat composition and the second basecoat composition are each independently covalently bonded to at least a portion of the polymeric shell of the core-shell particles. |
| FILED | Thursday, January 19, 2017 |
| APPL NO | 16/086253 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/0254 (20130101) B05D 5/061 (20130101) B05D 7/14 (20130101) B05D 7/24 (20130101) B05D 7/574 (20130101) Original (OR) Class Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 175/04 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 13/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198177 | Fang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| ASSIGNEE(S) | University of Utah Research Foundation (Salt Lake City, Utah) |
| INVENTOR(S) | Zhigang Zak Fang (Salt Lake City, Utah); Pei Sun (Salt Lake City, Utah) |
| ABSTRACT | A method of printing a three dimensional article (201) can include forming a bottom layer of the three dimensional article (201) by spraying a dry build material powder (210) onto a build platform (230) while heating the dry build material powder (210). The dry build material powder (210) can include metal or ceramic particles mixed with a polymeric binder having a softening point temperature. The dry build material powder (210) can be heated to a temperature above the softening point temperature such that the dry build material powder (210) adheres to the build platform (230). Subsequent layers can be formed by spraying dry build material powder (210) onto a lower layer while heating the dry build material powder (210) such that the dry build material powder (210) adheres to the lower layer. |
| FILED | Wednesday, September 05, 2018 |
| APPL NO | 16/644928 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 1/0059 (20130101) B22F 3/115 (20130101) Original (OR) Class B22F 3/1028 (20130101) B22F 10/10 (20210101) B22F 12/00 (20210101) B22F 2201/02 (20130101) B22F 2201/11 (20130101) B22F 2201/50 (20130101) Shaping Clay or Other Ceramic Compositions; Shaping Slag; Shaping Mixtures Containing Cementitious Material, e.g Plaster B28B 1/001 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198196 | Elhadj et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Selim Elhadj (Livermore, California); Jae Hyuck Yoo (Dublin, California) |
| ABSTRACT | The present disclosure relates to a method of modifying a surface of a material, in situ, while the material is being used to at least one of form or modify a portion of a part to remove flaws layer-by-layer and improve a part from a layerwise built, or a coating. The method may involve generating first, second and third beams. The third beam may act on a surface of a material to heat a portion of the surface of the material into a flowable state to thus modify a surface characteristic of the material. The first beam may control an optically addressable light valve (OALV) which modifies an energy of the third beam. The second beam may control an optically addressable electric field modulator (OAEFM) to generate an electric field in a vicinity of the surface and to influence a movement of the portion of material while the portion of material is in the flowable state. The beams are modulated based on a sensing element feedback loop. |
| FILED | Wednesday, March 21, 2018 |
| APPL NO | 15/927465 |
| ART UNIT | 3761 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/032 (20130101) B23K 26/064 (20151001) B23K 26/342 (20151001) Original (OR) Class B23K 26/0608 (20130101) B23K 26/0626 (20130101) B23K 26/0676 (20130101) B23K 26/702 (20151001) B23K 26/0869 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) Optical Elements, Systems, or Apparatus G02B 27/283 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/135 (20130101) G02F 1/133362 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198871 | Marcano et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| INVENTOR(S) | Joan Gabriel Marcano (Denver, Colorado); Katherine Jenyan Chou (Lakewood, Colorado) |
| ABSTRACT | Methods of riboswitch-mediated gene expression in thermophiles are provided herein. |
| FILED | Monday, February 17, 2020 |
| APPL NO | 16/792761 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198880 | Kerfeld et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Cheryl A. Kerfeld (Walnut Creek, California); Jonathan K. Lassila (South San Francisco, California); James N. Kinney (Clayton, California); Markus Sutter (Berkeley, California); Steven C. Wilson (Rohnert Park, California) |
| ABSTRACT | To produce a bacterial microcompartment shell, or a designed shell based on naturally occurring bacterial microcompartment shells in a new host organism, a synthetic operon is constructed that contains the desired shell protein genes and translation efficiency is controlled by host specific ribosomal binding sites. Proteins or other molecules can be encapsulated in the microcompartment shells by various methods described herein. The constructs can also be used to express self-assembling sheets comprised of shell proteins. |
| FILED | Thursday, December 01, 2016 |
| APPL NO | 15/367089 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Peptides C07K 14/35 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0008 (20130101) C12N 15/52 (20130101) C12N 15/65 (20130101) C12N 15/67 (20130101) C12N 15/70 (20130101) Original (OR) Class C12N 15/81 (20130101) Enzymes C12Y 102/01004 (20130101) C12Y 401/01039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198941 | He et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Ting He (Idaho Falls, Idaho); Dong Ding (Idaho Falls, Idaho); Wei Wu (Idaho Falls, Idaho) |
| ABSTRACT | A method of producing hydrogen gas comprises introducing gaseous water to an electrolysis cell comprising a positive electrode, a negative electrode, and a proton conducting membrane between the positive electrode and the negative electrode. The proton conducting membrane comprises an electrolyte material having an ionic conductivity greater than or equal to about 10−2 S/cm at one or more temperatures within a range of from about 150° C. to about 650° C. The gaseous water is decomposed using the electrolysis cell. A hydrogen gas production system and an electrolysis cell are also described. |
| FILED | Thursday, February 01, 2018 |
| APPL NO | 16/483631 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) Original (OR) Class C25B 1/042 (20210101) C25B 9/23 (20210101) C25B 9/73 (20210101) C25B 11/047 (20210101) C25B 13/07 (20210101) C25B 15/021 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199485 | Nation et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| INVENTOR(S) | Brendan L. Nation (Albuquerque, New Mexico); Michael T. Dugger (Tijeras, New Mexico); John Curry (Albuquerque, New Mexico) |
| ABSTRACT | The present invention relates, in part, to systems for characterizing force (e.g., friction, wear, and/or torque). In one embodiment, the system allows for wear testing of samples in a high throughput manner. In another embodiment, the system allows for torque sensing in a non-contact manner. |
| FILED | Tuesday, July 16, 2019 |
| APPL NO | 16/513197 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 3/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/02 (20130101) G01N 3/56 (20130101) Original (OR) Class G01N 21/27 (20130101) G01N 2201/08 (20130101) G01N 2201/063 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199517 | Kunc et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Vlastimil Kunc (Knoxville, Tennessee); Ahmed A. Hassen (Knoxville, Tennessee); Pooran C. Joshi (Knoxville, Tennessee); Seokpum Kim (Knoxville, Tennessee); John M. Lindahl (Powell, Tennessee); Chad E. Duty (Loudon, Tennessee); Jordan A. Failla (Knoxville, Tennessee); Tyler C. H. Smith (Knoxville, Tennessee) |
| ABSTRACT | A structural health monitoring method is provided that utilizes self-sensing printed polymer structures. The method is based on resistivity properties of conductive materials, which can be integrated to a 3D printed polymer structure during additive manufacturing. An article to be monitored has at least one 3D printed polymer structure including a circuit comprising at least one conductive pathway extending through a non-conductive material. The resistance across the circuit is measured during or after loading of the article to determine a resistance value. The measured resistance value is compared to a known resistance value, and based on the comparison, a defect can be detected in the 3D printed polymer structure. Structural health monitoring systems and articles with integrated structural health monitoring are also provided. |
| FILED | Tuesday, August 13, 2019 |
| APPL NO | 16/539184 |
| ART UNIT | 2868 — Printing/Measuring and Testing |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/30 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/20 (20130101) Original (OR) Class G01N 27/041 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200168 | Johns et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Charles R. Johns (Austin, Texas); Jose R. Brunheroto (Mohegan Lake, New York) |
| ABSTRACT | An approach is disclosed that caches distant memories within the storage a local node. The approach provides a memory caching infrastructure that supports virtual addressing by utilizing memory in the local node as a cache of distant memories for data granules. The data granules are accessed along with metadata and an ECC associated with the data granule. The metadata is updated to indicate storage of the selected data granule in the cache. |
| FILED | Monday, December 10, 2018 |
| APPL NO | 16/214597 |
| ART UNIT | 2184 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 11/1076 (20130101) G06F 12/0815 (20130101) Original (OR) Class G06F 2212/608 (20130101) G06F 2212/1008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200474 | Swager et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Timothy M. Swager (Newton, Massachusetts); Joseph Michael Azzarelli (Cambridge, Massachusetts); Rong Zhu (Waltham, Massachusetts) |
| ABSTRACT | A wireless sensor platform design and a single walled carbon nanotube/ionic liquid-based chemidosimeter system can incorporated into a highly sensitive and selective chemical hazard badge that can dosimetrically detect an analyte down to a sub parts-per-million concentration. |
| FILED | Tuesday, December 31, 2019 |
| APPL NO | 16/732095 |
| ART UNIT | 2876 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/082 (20130101) A61B 5/4845 (20130101) A61B 2562/029 (20130101) A61B 2562/0285 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/122 (20130101) G01N 27/127 (20130101) G01N 27/4146 (20130101) G01N 33/0057 (20130101) G01N 33/0075 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 19/0717 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 50/265 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201028 | Lagally et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); The Regents of the University of New Mexico (Albuquerque, New Mexico) |
| INVENTOR(S) | Max G. Lagally (Madison, Wisconsin); Matthew McLean Dwyer (Madison, Wisconsin); Francesca Cavallo (Albuquerque, New Mexico); Daniel Warren van der Weide (Madison, Washington); Abhishek Bhat (Madison, Wisconsin) |
| ABSTRACT | Traveling-wave tube amplifiers for high-frequency signals, including terahertz signals, and methods for making a slow-wave structure for the traveling-wave tube amplifiers are provided. The slow-wave structures include helical conductors that are self-assembled via the release and relaxation of strained films from a sacrificial growth substrate. |
| FILED | Tuesday, October 01, 2019 |
| APPL NO | 16/589348 |
| ART UNIT | 2843 — Semiconductors/Memory |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 9/14 (20130101) H01J 23/24 (20130101) H01J 23/26 (20130101) Original (OR) Class H01J 25/34 (20130101) H01J 25/44 (20130101) H01J 2209/012 (20130101) Amplifiers H03F 3/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201324 | Hryn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| INVENTOR(S) | John N. Hryn (Naperville, Illinois); Patricia Ignacio-de Leon (Westmont, Illinois); Jeffrey S. Spangenberger (Plainfield, Illinois) |
| ABSTRACT | Methods and systems for producing lithium metal through room temperature electrodeposition. |
| FILED | Tuesday, September 18, 2018 |
| APPL NO | 16/134378 |
| ART UNIT | 1794 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Processes for the Electrolytic Production, Recovery or Refining of Metals; Apparatus Therefor C25C 1/02 (20130101) C25C 3/02 (20130101) C25C 7/04 (20130101) C25C 7/005 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) Original (OR) Class H01M 4/623 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201325 | Takeuchi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Brookhaven Science Associates, LLC (Upton, New York); The Research Foundation for The State University of new York (Albany, New York) |
| ASSIGNEE(S) | BROOKHAVEN SCIENCE ASSOCIATES, LLC (Upton, New York); The Research Foundation of The University of New York (Albany, New York) |
| INVENTOR(S) | Esther Sans Takeuchi (South Setauket, New York); Altug S. Poyraz (Kennesaw, Georgia); Kenneth James Takeuchi (South Setauket, New York); Amy Catherine Marschilok (Stony Brook, New York) |
| ABSTRACT | A binder-free, self-supporting electrode including an electrochemically active material in the absence of a binder and a current collector is claimed. The electrochemically active material is a self-supporting transition metal oxide. A method of regenerating the electrode to restore capacity of the electrode is also claimed. |
| FILED | Monday, November 28, 2016 |
| APPL NO | 15/772564 |
| ART UNIT | 1727 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 45/1228 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2006/40 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/48 (20130101) H01M 4/131 (20130101) H01M 4/505 (20130101) Original (OR) Class H01M 4/624 (20130101) H01M 4/625 (20130101) H01M 10/052 (20130101) H01M 10/54 (20130101) H01M 2220/30 (20130101) Climate Change Mitigation Technologies Related to Transportation Y02T 10/70 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/84 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201337 | Jolly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
| ASSIGNEE(S) | FuelCell Energy, Inc. (Danbury, Connecticut) |
| INVENTOR(S) | Stephen Jolly (Southington, Connecticut); Frank J. Chimbole, Jr. (Danbury, Connecticut); Fred C. Jahnke (Rye, New York); Jonathan Malwitz (Danbury, Connecticut); Hossein Ghezel-Ayagh (New Milford, Connecticut) |
| ABSTRACT | A fuel cell system includes an anode configured to output an anode exhaust stream comprising hydrogen, carbon dioxide, and water; and a membrane dryer configured to receive the anode exhaust stream, remove water from the anode exhaust stream, and output a membrane dryer outlet stream. The membrane dryer includes a first chamber configured to receive the anode exhaust stream; a second chamber configured to receive a purge gas; and a semi-permeable membrane separating the first chamber and the second chamber. The semi-permeable membrane is configured to allow water to diffuse therethrough, thereby removing water from the anode exhaust stream. The membrane dryer may further be configured to remove hydrogen from the anode exhaust stream. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/229285 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0668 (20130101) H01M 8/0687 (20130101) H01M 8/04149 (20130101) Original (OR) Class H01M 8/04164 (20130101) H01M 8/04514 (20130101) H01M 8/04843 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201349 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Zhuoying Zhu (La Jolla, California); Shyue Ping Ong (La Jolla, California); Erik Wu (La Jolla, California); Han Nguyen (La Jolla, California); Ying Shirley Meng (La Jolla, California); Iek Heng Chu (La Jolla, California) |
| ABSTRACT | Presented are new, earth-abundant lithium superionic conductors, Li3Y(PS4)2 and L15PS4Cl2, that emerged from a comprehensive screening of the Li—P—S and Li—M—P—S chemical spaces. Both candidates are derived from the relatively unexplored quaternary silver thiophosphates. One key enabler of this discovery is the development of a first-of-its-kind high-throughput first principles screening approach that can exclude candidates unlikely to satisfy the stringent Li+ conductivity requirements using a minimum of computational resources. Both candidates are predicted to be synthesizable, and are electronically insulating. Systems and methods according to present principles enable new, all-solid-state rechargeable lithium-ion batteries. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 16/346144 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/00 (20190201) G16C 20/30 (20190201) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/381 (20130101) H01M 4/382 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201532 | Freiberger |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Peter D. Freiberger (Belton, Missouri) |
| ABSTRACT | A precision triggering mechanism for engaging a portion of a device and a method of using the same are provided. The mechanism comprises an electric linear motor, a force limiter, a force sensor, an engagement slide, and a controller. The electric linear motor includes a drive rod, a driver that applies a force to the drive rod to move the drive rod linearly, and a sensor for detecting a linear position of the drive rod. The force limiter is connected to the drive rod and is configured to absorb an amount of axial force asserted by the drive rod above a maximum amount. The force sensor is connected to the force limiter and is configured to detect an amount of force applied by the force limiter on the force sensor. The engagement slide includes an end extending from the force sensor for engaging the portion of the device. The controller is configured to receive a signal representative of the linear position of the drive rod from the sensor of the electric linear motor; receive from the force sensor a signal representative of the amount of force applied by the force limiter; and direct the driver of the electric linear motor to apply a force to the drive rod based on at least one of the linear position of the drive rod or the amount of force applied by the force limiter. |
| FILED | Tuesday, December 10, 2019 |
| APPL NO | 16/709066 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 5/04 (20130101) H02K 7/08 (20130101) H02K 11/20 (20160101) H02K 11/33 (20160101) H02K 41/02 (20130101) Original (OR) Class H02K 41/0354 (20130101) H02K 41/0356 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201562 | Wasynczuk et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Oleg Wasynczuk (West Lafayette, Indiana); Minyu Cai (Roseville, Minnesota) |
| ABSTRACT | An auxiliary resonant soft-edge pole inverter circuit is provided. The power inverter circuitry may include a first pair of capacitors in parallel with a corresponding pair of main power switching modules, each power switching module comprising a switch and a diode in parallel and sharing a common central node with the first pair of capacitors. The power inverter circuit may further include a first pair of auxiliary switches connected in series with a first pair of inductors, respectively, to generate resonant current from a DC power source, the first pair of inductors also sharing the common central node. The power inverter circuitry may further include a second pair of auxiliary switches connected in series with a second pair of capacitors, respectively, the second pair of auxiliary switches also sharing the common central node, the circuit producing an alternating current output at the common central node. |
| FILED | Friday, May 29, 2020 |
| APPL NO | 16/887013 |
| ART UNIT | 2839 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 7/4811 (20210501) Original (OR) Class H02M 7/4815 (20210501) H02M 7/5387 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11197726 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Jaeyoun Kim (Ames, Iowa); In Ho Cho (Ames, Iowa); Jungwook Paek (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Jaeyoun Kim (Ames, Iowa); In Ho Cho (Ames, Iowa); Jungwook Paek (Philadelphia, Pennsylvania) |
| ABSTRACT | Elastomer-based soft-robotic micro-tentacles capable of winding around and holding microscale objects and methods of fabricating same are provided. To realize the thin, highly deformable microtubes, a fabrication technique based on in situ thermal solidification of PDMS dip-coated around a cylindrical template and direct peeling of the cured structure is presented. This process is capable to asymmetrize the microtube's cross-sectional shape and enable the microtube to bend up to a single turn. To amplify the bending into a life-like, multi-turn spiraling motion, a semi-analytical model to shape-engineer the microtube and turn it into a micro-tentacle was produced. As a result, a hump is added to the microtube to enable the multi-turn spiraling motion. |
| FILED | Thursday, November 03, 2016 |
| APPL NO | 15/342829 |
| ART UNIT | 1742 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 34/30 (20160201) Original (OR) Class A61B 2017/00526 (20130101) A61B 2017/00544 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197768 | Sikdar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | George Mason University (Fairfax, Virginia) |
| ASSIGNEE(S) | GEORGE MASON UNIVERSITY (Fairfax, Virginia) |
| INVENTOR(S) | Siddhartha Sikdar (Washington, District of Columbia); Joseph J. Pancrazio (Boyds, Maryland); Ira A. Hunt (McLean, Virginia); Andrew J. Nelson (Burke, Virginia); Abdullah Al-Imran (Herndon, Virginia) |
| ABSTRACT | The artificial body part control system using ultrasonic imaging includes of an ultrasonic transducer coupled with an ultrasonic image analyzer which may be adapted to transmit a control signal to an artificial body part. |
| FILED | Tuesday, March 27, 2018 |
| APPL NO | 15/937613 |
| ART UNIT | 3799 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1107 (20130101) A61B 8/085 (20130101) A61B 8/4227 (20130101) A61B 8/5223 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/72 (20130101) Original (OR) Class A61F 2/583 (20130101) A61F 2002/6809 (20130101) A61F 2002/7615 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197932 | Camacho et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Kathryn M. Camacho (Los Angeles, California); Stefano Menegatti (Raleigh, North Carolina); Sunny Kumar (Aliso Viejo, California); Douglas Vogus (Goleta, California); Samir Mitragotri (Lexington, Massachusetts) |
| ABSTRACT | Pharmaceutical compositions comprising two or more therapeutically active agents, such as two or more anticancer agents, conjugated to one or more biocompatible polymers, wherein the molar ratio of the agents and/or schedules of delivery provide a synergistic therapeutic effect, are described. Methods of making and using the pharmaceutical compositions are further described. In one embodiment, the pharmaceutical compositions contain topoisomerase I and topoisomerase II inhibitors conjugated to the same or different biocompatible polymers. The two or more anticancer agents are covalently coupled to the polymer(s), and thereby can be delivered to a tumor at a molar ratio which provides a synergistic effect. Optionally, the agents are coupled indirectly to the polymer(s) via a linker. |
| FILED | Monday, April 13, 2020 |
| APPL NO | 16/846707 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/704 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 47/61 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197944 | Cezar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); CHARITE UNIVERSITAETSMEDIZIN BERLIN (Berlin, Germany) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts); CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN (Berlin, Germany) |
| INVENTOR(S) | Christine A. Cezar (Cambridge, Massachusetts); Conor J. Walsh (Cambridge, Massachusetts); David J. Mooney (Sudbury, Massachusetts); Ellen T. Roche (Galway, Ireland); Herman H. Vandenburgh (Providence, Rhode Island); Georg N. Duda (Berlin, Germany) |
| ABSTRACT | The present invention provides methods and compositions for promoting regeneration of a tissue, methods for preventing or reducing inflammation of a tissue, methods for preventing or reducing fibrosis of a tissue, methods for increasing a mass of a tissue, methods for increasing a level of oxygen available to a tissue, methods for increasing a rate of metabolic waste removal from a tissue, methods for increasing blood perfusion to a tissue, and methods of treating severe muscle tissue damage in a subject in need thereof by contacting the tissue with a composition that is suitable for applying cyclic mechanical compression to the tissue. |
| FILED | Friday, November 18, 2016 |
| APPL NO | 15/776853 |
| ART UNIT | 1613 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/14 (20130101) A61L 27/042 (20130101) Original (OR) Class A61L 27/56 (20130101) A61L 2400/06 (20130101) A61L 2430/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198127 | Sulchek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| INVENTOR(S) | Todd Sulchek (Atlanta, Georgia); Alexander Alexeev (Atlanta, Georgia); Anna Liu (Atlanta, Georgia) |
| ABSTRACT | Embodiments of the present disclosure can include a method for convective intracellular delivery including providing cells and molecules to a microchannel having compressive surfaces, wherein the compressive surfaces define compression gaps having a height of from 20 and 80% of the average cell diameter; and a plurality of relaxation spaces disposed between the compressive surfaces; flowing the cell medium through the microchannel, wherein as the cell medium flows through the microchannel, the plurality of cells undergo a convective intracellular delivery process comprising: compressing the plurality of cells, wherein the compressing causes the plurality of cells to undergo a loss in intracellular volume (Vloss); and passing the plurality of cells to a first relaxation space, wherein the plurality of cells undergo a gain in volume (Vgain) and absorb a portion of the plurality of molecules. |
| FILED | Wednesday, November 08, 2017 |
| APPL NO | 16/348170 |
| ART UNIT | 1653 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Original (OR) Class B01L 2300/08 (20130101) B01L 2300/123 (20130101) B01L 2400/086 (20130101) B01L 2400/0463 (20130101) B01L 2400/0487 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/16 (20130101) C12M 35/04 (20130101) C12M 47/04 (20130101) C12M 99/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/06 (20130101) C12N 15/87 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198715 | Keating et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| ASSIGNEE(S) | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (Cambridge, Massachusetts) |
| INVENTOR(S) | Amy Keating (Arlington, Massachusetts); Justin Michael Jenson (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are compounds comprising peptides that bind Bfl-1. Also provided are compositions containing these peptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the peptides. |
| FILED | Friday, July 21, 2017 |
| APPL NO | 16/319199 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 1/113 (20130101) C07K 14/00 (20130101) C07K 14/395 (20130101) C07K 14/4747 (20130101) Original (OR) Class C07K 2319/00 (20130101) C07K 2319/10 (20130101) C07K 2319/42 (20130101) C07K 2319/43 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/50 (20130101) G01N 33/574 (20130101) G01N 2333/4703 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198880 | Kerfeld et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Cheryl A. Kerfeld (Walnut Creek, California); Jonathan K. Lassila (South San Francisco, California); James N. Kinney (Clayton, California); Markus Sutter (Berkeley, California); Steven C. Wilson (Rohnert Park, California) |
| ABSTRACT | To produce a bacterial microcompartment shell, or a designed shell based on naturally occurring bacterial microcompartment shells in a new host organism, a synthetic operon is constructed that contains the desired shell protein genes and translation efficiency is controlled by host specific ribosomal binding sites. Proteins or other molecules can be encapsulated in the microcompartment shells by various methods described herein. The constructs can also be used to express self-assembling sheets comprised of shell proteins. |
| FILED | Thursday, December 01, 2016 |
| APPL NO | 15/367089 |
| ART UNIT | 1663 — Plants |
| CURRENT CPC | Peptides C07K 14/35 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0008 (20130101) C12N 15/52 (20130101) C12N 15/65 (20130101) C12N 15/67 (20130101) C12N 15/70 (20130101) Original (OR) Class C12N 15/81 (20130101) Enzymes C12Y 102/01004 (20130101) C12Y 401/01039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199412 | Kordari et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRX SYSTEMS, INC. (Greenbelt, Maryland) |
| ASSIGNEE(S) | TRX SYSTEMS, INC. (Greenbelt, Maryland) |
| INVENTOR(S) | Kamiar Kordari (McLean, Virginia); Benjamin Funk (Hanover, Maryland); Carole Teolis (Glenn Dale, Maryland); Jared Napora (Severn, Maryland); John Karvounis (Bowie, Maryland); Dan Hakim (Silver Spring, Maryland); Christopher Giles (Prince Frederick, Maryland); Carol Politi (Bethesda, Maryland) |
| ABSTRACT | This disclosure provides techniques for the creation of maps of indoor spaces. In these techniques, an individual or a team with no mapping or cartography expertise can contribute to the creation of maps of buildings, campuses or cities. An indoor location system can track the location of contributors in the building. As they walk through indoor spaces, an application may automatically create a map based on data from motion sensors by both tracking the location of the contributors and also inferring building features such as hallways, stairways, and elevators based on the tracked contributors' motions as they move through a structure. With these techniques, the process of mapping buildings can be crowd sourced to a large number of contributors, making the indoor mapping process efficient and easy to scale up. |
| FILED | Thursday, June 28, 2018 |
| APPL NO | 16/022526 |
| ART UNIT | 3668 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/206 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199447 | Hu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (, None) |
| INVENTOR(S) | Jiamian Hu (Middleton, Wisconsin); Shihao Zhuang (Madison, Wisconsin) |
| ABSTRACT | Acoustically mediated spintronic THz emitters based on a stacked, multilayered heterostructure that includes a light-to-acoustic transducer layer, a thermal insulation layer, and a magnetic layer are provided. In the emitters, fast acoustic pulses give rise to long-distance propagation of THz exchange spin waves in a magnetic film. Also provided are THz time-domain spectrometers (THz-TDSs) that incorporate the THz emitters. |
| FILED | Tuesday, October 20, 2020 |
| APPL NO | 17/074756 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/108 (20130101) Original (OR) Class G01J 3/453 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 1/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199460 | Yin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington); The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Jianzhu Yin (Seattle, Washington); Jonathan Posner (Seattle, Washington); Veronica J. Santos (Oakland, California) |
| ABSTRACT | An example sensor device is provided. The sensor device includes (a) a substrate having a first end and a second end, wherein the substrate includes a contact portion, a first sensor portion positioned between the first end of the substrate and the contact portion, and a second sensor portion positioned between the second end of the substrate and the contact portion, (b) a first strain gauge sensor positioned at the first sensor portion, and (c) a second strain gauge sensor positioned at the second sensor portion, wherein the first end of the substrate and the second end of the substrate are configured to be coupled to a rigid curved surface, and wherein the sensor device is configured such that a force applied to the contact portion of the substrate will be sensed by each of the first strain gauge sensor and the second strain gauge sensor. |
| FILED | Wednesday, March 21, 2018 |
| APPL NO | 16/496164 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/2287 (20130101) G01L 5/161 (20130101) G01L 5/226 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199535 | Maric et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | Radenka Maric (Andover, Connecticut); Rishabh Jain (Hillsboro, Oregon) |
| ABSTRACT | Improved sensor assemblies are provided. More particularly, the present disclosure provides improved and highly advantageous metal oxide based sensor assemblies configured to sense low concentration of specific gases, and related methods of use. The present disclosure provides improved physical forms of metal oxide films (e.g., WOx films, CeOx films). The exemplary metal oxide films can be fabricated by a Reactive Spray Deposition Technology (RSDT). The highly advantageous films/materials can be utilized in sensor assemblies to detect simple chemical components of the breath that correlate with human health conditions (e.g., the presence of acetone in diabetic patients). These films/materials demonstrate improved thermal stability under the sensor's operating conditions, as well as improved sensitivity to low concentration of the analyte, selectivity and quick responsiveness. |
| FILED | Thursday, October 10, 2019 |
| APPL NO | 16/598903 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/127 (20130101) G01N 33/0037 (20130101) G01N 33/0047 (20130101) G01N 33/497 (20130101) Original (OR) Class G01N 2033/4975 (20130101) Technologies for Adaptation to Climate Change Y02A 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199691 | Vaziri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Alipasha Vaziri (Greenwich, Connecticut); Tobias Noebauer (New York, New York); Oliver Skocek (Engelhartstetten, Austria) |
| ABSTRACT | An imaging signal extraction apparatus comprising: an interface; a processing device, the processing device operatively coupled to the interface; and a computer readable medium comprising instructions that, when executed by the processing device, perform operations comprising: a) generating a two-dimensional image from imaging information obtained from the interface, thereby estimating ballistic component of the imaging information; b) generating a three-dimensional image by remapping the two-dimensional image; c) identifying a candidate object in the three-dimensional image; d) obtaining an estimated spatial forward model of the candidate object by mapping the three-dimensional image of the candidate object with a point-spread-function associated with the imaging apparatus; e) obtaining background-corrected data by using the estimated spatial forward model of the candidate object and estimated temporal components; and f) iteratively updating the estimated spatial forward model and estimated temporal components until convergence is reached for the candidate object, thereby extracting the signal information. |
| FILED | Wednesday, October 07, 2020 |
| APPL NO | 17/065499 |
| ART UNIT | 2422 — Cable and Television |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/367 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199838 | Chowdhary et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| INVENTOR(S) | Girish Chowdhary (Champaign, Illinois); Chinmay P. Soman (Urbana, Illinois); Beau David Barber (Ogden, Illinois) |
| ABSTRACT | The present disclosure provides a system for monitoring unstructured environments. A predetermined path can be determined according to an assignment of geolocations to one or more agronomically anomalous target areas, where the one or more agronomically anomalous target areas are determined according to an analysis of a plurality of first images that automatically identifies a target area that deviates from a determination of an average of the plurality of first images that represents an anomalous place within a predetermined area, where the plurality of first images of the predetermined area are captured by a camera during a flight over the predetermined area. A camera of an unmanned vehicle can capture at least one second image of the one or more agronomically anomalous target areas as the unmanned vehicle travels along the predetermined path. |
| FILED | Monday, January 22, 2018 |
| APPL NO | 16/480076 |
| ART UNIT | 3663 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0038 (20130101) Original (OR) Class Electric Digital Data Processing G06F 16/29 (20190101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00657 (20130101) G06K 9/6263 (20130101) G06K 2009/00644 (20130101) Traffic Control Systems G08G 5/0039 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200350 | Gligor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Virgil D. Gligor (Pittsburgh, Pennsylvania); Zongwei Zhou (Mountain View, California); Miao Yu (Pittsburgh, Pennsylvania) |
| ABSTRACT | This invention provides a method for providing trusted display to security sensitive applications on untrusted computing platforms. This invention has a minimal trusted code base and maintains full compatibility with the computing platforms, including their software and hardware. The core of the invention is a GPU separation kernel that (1) defines different types of GPU objects, (2) mediates access to security-sensitive GPU objects, and (3) emulates accesses to security-sensitive GPU objects whenever required by computing platform compatibility. |
| FILED | Thursday, July 23, 2020 |
| APPL NO | 16/937183 |
| ART UNIT | 2438 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45508 (20130101) G06F 9/45558 (20130101) G06F 21/53 (20130101) G06F 21/57 (20130101) G06F 21/62 (20130101) G06F 21/70 (20130101) G06F 21/71 (20130101) G06F 21/84 (20130101) Original (OR) Class G06F 2221/2141 (20130101) G06F 2221/2149 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/1491 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200354 | De Sapio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Vincent De Sapio (Westlake Village, California); Kang-Yu Ni (Calabasas, California); Tsai-Ching Lu (Thousand Oaks, California) |
| ABSTRACT | Described is a system for selecting measurement nodes in a distributed physical system of agents. In operation, the distributed physical system is represented as a multi-layer network having a communication layer and an agent layer. The communication layer represents the amount of collective communication activities between any pair of areas and the agent layer represents movement of agents within the distributed physical system such that the communication layer and agent layer collectively generate network dynamics. The network dynamics are modeled as hybrid partial differential equations (PDEs) with measurable interconnected states in the communication layer. Notably, placement of a minimum set of measurement nodes is determined within the distributed physical system to provide full-state observability of the distributed physical system. The system can then track the full system state and apply compensation to one or more agents in the distributed physical system based on tracking the full system state. |
| FILED | Friday, January 17, 2020 |
| APPL NO | 16/746436 |
| ART UNIT | 2194 — Interprocess Communication and Software Development |
| CURRENT CPC | Electric Digital Data Processing G06F 17/13 (20130101) G06F 30/18 (20200101) Original (OR) Class G06F 2111/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200637 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Yu Charlie Hu (West Lafayette, Indiana); Ning Ding (Santa Clara, California) |
| ABSTRACT | A method for profiling energy usage in graphics user interfaces (UI) in handheld mobile devices is disclosed, which includes quantifying the central processing unit (CPU) energy drain of each UI update, quantifying the graphics processing unit (GPU) energy drain of each UI update, quantifying the number of pixels changed due to each UI update, identifying an UI update that consumes energy drain but results in no pixel changes to the displayed frame as a graphics energy bug. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 16/853709 |
| ART UNIT | 2612 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 1/28 (20130101) G06F 9/451 (20180201) G06F 11/3024 (20130101) G06F 11/3058 (20130101) Image Data Processing or Generation, in General G06T 1/20 (20130101) Original (OR) Class G06T 2200/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200672 | Cranmer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio); The Penn State Research Foundation (University Park, Pennsylvania); University of North Carolina (Chapel Hill, North Carolina); University of San Francisco (San Francisco, California) |
| ASSIGNEE(S) | Ohio State Innovation Foundation (Columbus, Ohio); The Penn State Research Foundation (University Park, Panama); University of North Carolina (Chapel Hill, North Carolina); University of San Francisco (San Francisco, California) |
| INVENTOR(S) | Skyler Cranmer (Columbus, Ohio); Bruce Desmarais (University Park, Pennsylvania); Shankar Bhamidi (Chapel Hill, North Carolina); James Wilson (San Francisco, California); Matthew Denny (University Park, Pennsylvania); Zhong-Lin Lu (Columbus, Ohio); Paul Stillman (Columbus, Ohio) |
| ABSTRACT | Systems and methods are described herein for modeling neural architecture. Regions of interest of a brain of a subject can be identified based on image data characterizing the brain of the subject. the identified regions of interest can be mapped to a connectivity matrix. The connectivity matrix can be a weighted and undirected network. A multivariate transformation can be applied to the connectivity matrix to transform the connectivity matrix into a partial correlation matrix. The multivariate transformation can maintain a positive definite constraint for the connectivity matrix. The partial correlation matrix can be transformed into a neural model indicative of the connectivity matrix. |
| FILED | Friday, March 05, 2021 |
| APPL NO | 17/193911 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0263 (20130101) A61B 5/369 (20210101) A61B 5/4064 (20130101) A61B 5/7267 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4806 (20130101) G01R 33/5608 (20130101) G01R 33/56341 (20130101) Electric Digital Data Processing G06F 17/16 (20130101) G06F 17/18 (20130101) Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6226 (20130101) Image Data Processing or Generation, in General G06T 7/0014 (20130101) Original (OR) Class G06T 2207/30016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201077 | Marinov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KULICKE and SOFFA NETHERLANDS B.V. (Eindhoven, Netherlands) |
| ASSIGNEE(S) | KULICKE and SOFFA NETHERLANDS B.V. (, None) |
| INVENTOR(S) | Val Marinov (Fargo, North Dakota); Ronn Kliger (Cambridge, Massachusetts); Matthew R. Semler (Fargo, North Dakota) |
| ABSTRACT | A method includes transferring multiple discrete components from a first substrate to a second substrate, including illuminating multiple regions on a top surface of a dynamic release layer, the dynamic release layer adhering the multiple discrete components to the first substrate, each of the irradiated regions being aligned with a corresponding one of the discrete components. The illuminating induces a plastic deformation in each of the irradiated regions of the dynamic release layer. The plastic deformation causes at least some of the discrete components to be concurrently released from the first substrate. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 16/621432 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/36 (20130101) B23K 26/354 (20151001) B23K 26/0673 (20130101) Optical Elements, Systems, or Apparatus G02B 27/1086 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/6836 (20130101) Original (OR) Class H01L 21/67115 (20130101) H01L 25/0753 (20130101) H01L 33/50 (20130101) H01L 33/62 (20130101) H01L 33/0095 (20130101) H01L 2221/68327 (20130101) H01L 2221/68363 (20130101) H01L 2221/68381 (20130101) H01L 2933/0066 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201349 | Zhu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Zhuoying Zhu (La Jolla, California); Shyue Ping Ong (La Jolla, California); Erik Wu (La Jolla, California); Han Nguyen (La Jolla, California); Ying Shirley Meng (La Jolla, California); Iek Heng Chu (La Jolla, California) |
| ABSTRACT | Presented are new, earth-abundant lithium superionic conductors, Li3Y(PS4)2 and L15PS4Cl2, that emerged from a comprehensive screening of the Li—P—S and Li—M—P—S chemical spaces. Both candidates are derived from the relatively unexplored quaternary silver thiophosphates. One key enabler of this discovery is the development of a first-of-its-kind high-throughput first principles screening approach that can exclude candidates unlikely to satisfy the stringent Li+ conductivity requirements using a minimum of computational resources. Both candidates are predicted to be synthesizable, and are electronically insulating. Systems and methods according to present principles enable new, all-solid-state rechargeable lithium-ion batteries. |
| FILED | Tuesday, October 31, 2017 |
| APPL NO | 16/346144 |
| ART UNIT | 2862 — Printing/Measuring and Testing |
| CURRENT CPC | Computational Chemistry; Chemoinformatics; Computational Materials Science G16C 20/00 (20190201) G16C 20/30 (20190201) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/381 (20130101) H01M 4/382 (20130101) H01M 10/052 (20130101) H01M 10/054 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201532 | Freiberger |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (Kansas City, Missouri) |
| INVENTOR(S) | Peter D. Freiberger (Belton, Missouri) |
| ABSTRACT | A precision triggering mechanism for engaging a portion of a device and a method of using the same are provided. The mechanism comprises an electric linear motor, a force limiter, a force sensor, an engagement slide, and a controller. The electric linear motor includes a drive rod, a driver that applies a force to the drive rod to move the drive rod linearly, and a sensor for detecting a linear position of the drive rod. The force limiter is connected to the drive rod and is configured to absorb an amount of axial force asserted by the drive rod above a maximum amount. The force sensor is connected to the force limiter and is configured to detect an amount of force applied by the force limiter on the force sensor. The engagement slide includes an end extending from the force sensor for engaging the portion of the device. The controller is configured to receive a signal representative of the linear position of the drive rod from the sensor of the electric linear motor; receive from the force sensor a signal representative of the amount of force applied by the force limiter; and direct the driver of the electric linear motor to apply a force to the drive rod based on at least one of the linear position of the drive rod or the amount of force applied by the force limiter. |
| FILED | Tuesday, December 10, 2019 |
| APPL NO | 16/709066 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 5/04 (20130101) H02K 7/08 (20130101) H02K 11/20 (20160101) H02K 11/33 (20160101) H02K 41/02 (20130101) Original (OR) Class H02K 41/0354 (20130101) H02K 41/0356 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11197435 | Cademartiri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| INVENTOR(S) | Ludovico Cademartiri (Ames, Iowa); Lin Ma (Ames, Iowa) |
| ABSTRACT | The described invention is directed to hydrogel-based transparent soils that can provide heterogeneous, aeration, and porous condition for plant growth. The hydrogel beads are highly tailorable in size and porosity providing an environment that is closer to natural soil. Index-matching allows the beads to appear transparent, facilitating the use of imaging and microscopy of the plant root system in vivo. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/107512 |
| ART UNIT | 3644 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 24/35 (20180201) Original (OR) Class Polysaccharides; Derivatives Thereof C08B 37/006 (20130101) C08B 37/0084 (20130101) Compositions of Macromolecular Compounds C08L 5/04 (20130101) C08L 2312/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/01 (20130101) G01N 21/35 (20130101) G01N 2021/0106 (20130101) G01N 2021/8466 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197879 | Brewster et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INGREDIENTS BY NATURE (Montclair, California); U.S. DEPARTMENT OF AGRICULTURE (Beltsville, Maryland) |
| ASSIGNEE(S) | INGREDIENTS BY NATURE (Montclair, California); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
| INVENTOR(S) | Robert M. Brewster (Montclair, California); John A. Manthey (Fort Pierce, Florida) |
| ABSTRACT | This invention relates to a flavonoid composition that includes eriocitrin. The flavonoid may be included in a complex with other bioflavonoids. The composition may also include neoeriocitrin. This invention also relates to methods of using the composition, including for reducing IL-6 or MCP-1 treating inflammation, and treating symptoms of metabolic syndrome. |
| FILED | Thursday, February 06, 2020 |
| APPL NO | 16/784010 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/353 (20130101) A61K 31/7048 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Heterocyclic Compounds C07D 311/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11198629 | Riefler |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OHIO UNIVERSITY (Athens, Ohio) |
| ASSIGNEE(S) | OHIO UNIVERSITY (Athens, Ohio) |
| INVENTOR(S) | R. Guy Riefler (Athens, Ohio) |
| ABSTRACT | Systems and methods for actively treating mining wastewater, such as acid mine drainage, using a mixed culture of iron oxidizing bacteria, in a manner that results in both remediation of the water and the production of a useful end product. Exemplary systems and methods employ a reaction vessel where the bacteria can oxidize the iron in the mining wastewater for some amount of time, and a settling tank into which reacted water may be transferred and retained to permit iron oxyhydroxide contained in the water to settle as iron oxyhydroxide sludge. The iron oxyhydroxide sludge may be dried to produce iron oxyhydroxide solids that can be employed in the manufacture of a usable pigment. |
| FILED | Friday, November 17, 2017 |
| APPL NO | 15/816542 |
| ART UNIT | 1779 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/66 (20130101) C02F 3/346 (20130101) Original (OR) Class C02F 11/12 (20130101) C02F 2001/007 (20130101) C02F 2101/203 (20130101) C02F 2103/10 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 2003/2265 (20130101) Treatment of Inorganic Materials, Other Than Fibrous Fillers, to Enhance Their Pigmenting or Filling Properties; Preparation of Carbon Black; C09C 1/24 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/61 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11200822 | Bae et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Euiwon Bae (West Lafayette, Indiana); Huisung Kim (Lafayette, Indiana) |
| ABSTRACT | A non-transitory computer-readable medium encoded with a computer-readable program, which when executed by a processor, will cause the processor to execute an image processing method, the image processing method including establishing a zero crossing region from a target image onto a screen, wherein the zero crossing region comprises a corresponding value. The method further includes receiving a variable input and an integration time input, wherein the variable input comprises a frequency number for an image accumulation procedure, and wherein the integration time comprises a time period for which an aperture for a sensor receives incoming signals. Additionally, the method includes performing the image accumulation procedure. Moreover, the method includes producing a final greyscale image by adding a plurality of sets of vertically shifted pixel values, wherein the frequency number for the image accumulation procedure ranges from 3 to 20. |
| FILED | Tuesday, July 14, 2020 |
| APPL NO | 16/927998 |
| ART UNIT | 2648 — Telecommunications: Analog Radio Telephone; Satellite and Power Control; Transceivers, Measuring and Testing; Bluetooth; Receivers and Transmitters; Equipment Details |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 5/20 (20130101) G06T 5/50 (20130101) G06T 2207/10016 (20130101) G06T 2207/10024 (20130101) G06T 2207/20182 (20130101) G06T 2207/30072 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/007 (20130101) Original (OR) Class G09G 5/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 11199630 | Kassas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zak Kassas (Irvine, California); Ali Abdallah (Irvine, California); Kimia Shamaei (Irvine, California) |
| ABSTRACT | Systems, device configurations and methods are provided for indoor localization for a navigator receiver based on broadband communication signals such as LTE. In one embodiment, an LTE-IMU framework determines receiver position indoors. Two different designs of LTE receivers are provided based on code phase and carrier phase determinations of the received signal. A base/navigator framework is presented to correct unknown clock biases of the LTE eNodeBs. In this framework, the base receiver is placed outdoors, has knowledge of its own position, and makes pseudorange measurements to eNodeBs in the environment whose positions are known. The base transmits these pseudoranges to the indoor navigating receiver, which is also making pseudorange measurements to the same eNodeBs. The navigating receiver differences the base and navigator pseudoranges. The navigator receiver is equipped with an extended Kalman filter (EKF) to fuse LTE and IMU measurements in a tightly-coupled fashion and estimate navigating receiver states. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/039843 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/43 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0048 (20130101) Wireless Communication Networks H04W 56/0005 (20130101) H04W 64/003 (20130101) H04W 64/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199772 | McMackin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Canon Nanotechnologies, Inc. (Austin, Texas) |
| ASSIGNEE(S) | Canon Nanotechnologies, Inc. (Austin, Texas) |
| INVENTOR(S) | Ian Matthew McMackin (Austin, Texas); Wesley Martin (Westfield, Indiana) |
| ABSTRACT | Methods for imprinting on abutted fields of a substrate are described. Generally, a first field of a substrate may be imprinted using an imprint lithography template. The template may then be placed such that a portion of the template overlaps the first field of the substrate while imprinting a second field of the substrate. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 16/437167 |
| ART UNIT | 1743 — Tires, Adhesive Bonding, Glass/Paper making, Plastics Shaping & Molding |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 40/00 (20130101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/0002 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11202062 | Rzhanov |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of New Hampshire (Durham, New Hampshire) |
| ASSIGNEE(S) | UNIVERSITY OF NEW HAMPSHIRE (Durham, New Hampshire) |
| INVENTOR(S) | Yuri Rzhanov (Durham, New Hampshire) |
| ABSTRACT | A system and method for colorimetric calibration is described herein. A system for performing color calibration is described, comprising at least one broad spectrum light emitting diode, at least one light diffuser plate, at least one interference filter, and a camera, the camera comprising at least one sensor for detection of colors, wherein a spectral response within 5% error of a ground truth method can be achieved. A method for performing color calibration is described, comprising transmitting light from at least one broad spectrum light emitting diode, scattering light with at least one light diffuser plate, filtering light with at least one interference filter, detecting light at a camera sensor, mapping an intensity value for each pixel of the camera sensor, and creating a quantum efficiency curve for each of red, green, and blue channels. |
| FILED | Tuesday, November 20, 2018 |
| APPL NO | 16/196425 |
| ART UNIT | 2422 — Cable and Television |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 9/0451 (20180801) H04N 17/002 (20130101) H04N 17/02 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11198181 | Hofmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Douglas C. Hofmann (Pasadena, California); Andre M. Pate (Pasadena, California) |
| ABSTRACT | Methods for the fabrication of metal strain wave gear flexsplines using a specialized metal additive manufacturing technique are provided. The method allows the entire flexspline to be metal printed, including all the components: the output surface with mating features, the thin wall of the cup, and the teeth integral to the flexspline. The flexspline may be used directly upon removal from the building tray. |
| FILED | Monday, March 12, 2018 |
| APPL NO | 15/918831 |
| ART UNIT | 1737 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Working Metallic Powder; Manufacture of Articles From Metallic Powder; Making Metallic Powder B22F 3/20 (20130101) B22F 5/08 (20130101) B22F 5/08 (20130101) B22F 5/08 (20130101) B22F 5/08 (20130101) B22F 9/002 (20130101) B22F 9/002 (20130101) B22F 10/10 (20210101) B22F 10/20 (20210101) Original (OR) Class B22F 10/20 (20210101) B22F 10/20 (20210101) B22F 10/20 (20210101) B22F 10/20 (20210101) B22F 10/20 (20210101) B22F 10/28 (20210101) B22F 2003/244 (20130101) B22F 2003/244 (20130101) B22F 2003/247 (20130101) B22F 2003/247 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2998/10 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) B22F 2999/00 (20130101) Making Gears or Toothed Racks B23F 5/163 (20130101) Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 9/04 (20130101) B23K 15/0086 (20130101) B23K 26/34 (20130101) B23K 26/354 (20151001) B23K 2101/008 (20180801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 70/00 (20141201) B33Y 80/00 (20141201) Gearing F16H 49/001 (20130101) F16H 55/06 (20130101) F16H 2049/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199005 | Fernandez |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| ASSIGNEE(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (Washington, District of Columbia) |
| INVENTOR(S) | Juan M. Fernandez (Norfolk, Virginia) |
| ABSTRACT | Various embodiments provide for bistable collapsible tubular mast (Bi-CTM) booms. Various embodiments provide CTM booms that may be bistable in nature, thereby achieving intrinsic benefits bistability may bring. Bistability may be achieved in various embodiments through specific combinations of the thin-shell cross-section geometry and the composite laminate selected for each thin-shell segment Additionally, in various embodiments, the thin-shell geometry of each boom half may be different. Various embodiments may include combinations of circular, ellipsoidal, or parabolic segments that form each shell. |
| FILED | Friday, July 05, 2019 |
| APPL NO | 16/503663 |
| ART UNIT | 3633 — Static Structures, Supports and Furniture |
| CURRENT CPC | Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2023/001 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/222 (20130101) Structural Elements; Building Materials E04C 2/296 (20130101) E04C 3/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11201358 | Dimpault-Darcy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | USA as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| ASSIGNEE(S) | United States of America as represented by the Administrator of the National Aeronautics and Space Administration (Washington, District of Columbia) |
| INVENTOR(S) | Eric C Dimpault-Darcy (Houston, Texas); John J. Darst (Houston, Texas); William Q. Walker (Houston, Texas); Steven L. Rickman (League City, Texas); Natalie N. Anderson (Crosby, Texas); Christiaan Khurana (Houston, Texas); Bruce L. Drolen (Altadena, California); Gary Bayles (Millersville, Maryland); Zoran Bilc (Houston, Texas) |
| ABSTRACT | A system for measuring a heat response of a cell during a thermal runaway event includes a housing. An insulation is positioned within the housing. A calorimeter is positioned within the insulation and the housing. The calorimeter is configured to have the cell positioned therein. The calorimeter is configured to measure a temperature increase of the cell, one or more components of the calorimeter, or a combination thereof during the thermal runaway event of the cell. A total energy yield of the thermal runaway event is configured to be determined based at least partially upon the temperature increase. A ratio is configured to be determined based at least partially upon the temperature increase. The ratio includes energy released through a casing of the cell during the thermal runaway event vs. energy released through ejecta material from the cell during the thermal runaway event. |
| FILED | Tuesday, October 30, 2018 |
| APPL NO | 16/175152 |
| ART UNIT | 2855 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Temperature; Measuring Quantity of Heat; Thermally-sensitive Elements Not Otherwise Provided for G01K 17/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/486 (20130101) H01M 10/4285 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11197933 | Jenkins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elysium Therapeutics, Inc. (Akron, Ohio) |
| ASSIGNEE(S) | Elysium Therapeutics, Inc. (Akron, Ohio) |
| INVENTOR(S) | Thomas E. Jenkins (Half Moon Bay, California); Craig O. Husfeld (San Mateo, California) |
| ABSTRACT | The invention provides compositions and methods for the treatment or prevention of pain. Compositions provided are resistant to overdose and abuse. Compositions provided comprise two or more different molecules, where each molecule comprises at least one GI enzyme-labile opioid agonist releasing subunit comprising an opioid agonist that is covalently linked to at least one GI enzyme inhibitor subunit. |
| FILED | Monday, September 16, 2019 |
| APPL NO | 16/572408 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/485 (20130101) A61K 47/55 (20170801) A61K 47/64 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11197952 | Young et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Advent Access Pte. Ltd. (Singapore, Singapore) |
| ASSIGNEE(S) | Advent Access Pte. Ltd. (Singapore, Singapore) |
| INVENTOR(S) | Nathaniel P. Young (Salt Lake City, Utah); Mark A. Crawford (Sandy, Utah) |
| ABSTRACT | A vascular access port can include a base that can be attached to a vessel and a body extending away from the base in at least a vertical direction. A height of the body in the vertical direction can be sufficiently small such that the entire port can be implanted subcutaneously in a patient. The port can include a guidance passageway that is at least partially defined by the body and can direct an access device into a vessel of a patient when the port is attached to the vessel. In some arrangements, the guidance passageway includes a funnel region that decreases in size from a proximal end of the guidance passageway toward a distal end of the guidance passageway that defines an opening through the bottom surface of the port. |
| FILED | Friday, April 19, 2019 |
| APPL NO | 16/389482 |
| ART UNIT | 3783 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 17/0057 (20130101) A61B 17/3423 (20130101) A61B 2017/3425 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 1/3653 (20130101) A61M 1/3659 (20140204) A61M 1/3661 (20140204) Original (OR) Class A61M 39/0208 (20130101) A61M 2205/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199462 | Sotoudeh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intelligent Fiber Optic Systems, Inc. (San Jose, California) |
| ASSIGNEE(S) | Intelligent Fiber Optic Systems, Inc. (San Jose, California) |
| INVENTOR(S) | Vahid Sotoudeh (Los Altos, California); Behzad Moslehi (Los Altos, California); Joshua Kuehn (Boulder Creek, California); Richard J. Black (Menlo Park, California) |
| ABSTRACT | A temperature correcting pressure gauge which has a diaphragm having at least one surface coupled to a source of pressure to be measured, the diaphragm first surface having a first FBG from a first optical fiber attached in an appropriately sensitive region of the diaphragm, a FBG from a second optical fiber attached to the opposite surface from the first FBG, the first and second FBGs reflecting or transmitting optical energy of decreasing or increasing wavelength, respectively, in response to an applied pressure. The first and second FBGs have nominal operating wavelength ranges that are adjacent to each other but are exclusive ranges and the FBGs also have closely matched pressure coefficients and temperature coefficients. |
| FILED | Wednesday, December 11, 2019 |
| APPL NO | 16/709936 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Measuring Force, Stress, Torque, Work, Mechanical Power, Mechanical Efficiency, or Fluid Pressure G01L 1/246 (20130101) G01L 11/025 (20130101) Original (OR) Class Optical Elements, Systems, or Apparatus G02B 6/0218 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 11199544 | Astatke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Mekbib Astatke (Gaithersburg, Maryland); Allyson M. Bissing-Gibson (Columbia, Maryland); Rachel S. Quizon (Olney, Maryland) |
| ABSTRACT | A method for a pre-symptomatic diagnosis of a viral illness in a subject is provided. The method may include obtaining a biological sample that includes at least one peripheral blood mononuclear cell from a subject prior to the subject experiencing any symptoms associated with the viral illness. The method may further include extracting proteins from the biological sample. The method may also include analyzing the extracted proteins, via mass spectrometry, for the presence of a predefined viral protein biomarker associated with the viral illness. If the predefined viral protein biomarker is present, the subject is diagnosed with the viral illness prior to experiencing the symptoms associated with the viral illness. |
| FILED | Friday, March 15, 2019 |
| APPL NO | 16/354238 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) Original (OR) Class G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11199691 | Vaziri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Alipasha Vaziri (Greenwich, Connecticut); Tobias Noebauer (New York, New York); Oliver Skocek (Engelhartstetten, Austria) |
| ABSTRACT | An imaging signal extraction apparatus comprising: an interface; a processing device, the processing device operatively coupled to the interface; and a computer readable medium comprising instructions that, when executed by the processing device, perform operations comprising: a) generating a two-dimensional image from imaging information obtained from the interface, thereby estimating ballistic component of the imaging information; b) generating a three-dimensional image by remapping the two-dimensional image; c) identifying a candidate object in the three-dimensional image; d) obtaining an estimated spatial forward model of the candidate object by mapping the three-dimensional image of the candidate object with a point-spread-function associated with the imaging apparatus; e) obtaining background-corrected data by using the estimated spatial forward model of the candidate object and estimated temporal components; and f) iteratively updating the estimated spatial forward model and estimated temporal components until convergence is reached for the candidate object, thereby extracting the signal information. |
| FILED | Wednesday, October 07, 2020 |
| APPL NO | 17/065499 |
| ART UNIT | 2422 — Cable and Television |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/367 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11197972 | Jacobs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Bryson Jacobs (Quaker Hill, Connecticut); Savannah Lyle (Saint Petersburg, Florida) |
| ABSTRACT | In an example, a ventilator includes an outer container containing liquid, an inverted container submerged in the liquid to provide inverted container space between a closed top and an inner container liquid level; gas supply line to supply breathing gas to the inverted container space; and inhalation line having an inlet in the inverted container space to provide breathing gas to patient. The inverted container moves upward from a first elevation when the inverted container space reaches a hydrostatic delivery pressure and volume of the inverted container space increases. The inverted container stops moving upward and the gas supply line stops supplying when the inverted container reaches a second elevation above the first. Based on a breath demand signal or preset timing, the inhalation line opens to permit flow of breathing gas to the patient at the hydrostatic delivery pressure, lowering the inverted container due to lost buoyancy resulting in sinkage. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244728 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 16/0003 (20140204) A61M 16/16 (20130101) Original (OR) Class A61M 16/208 (20130101) A61M 2205/3348 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Justice (DOJ)
| US 11199498 | Blair |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Richard George Blair (Ovledo, Florida) |
| ABSTRACT | A portable spectrometer system is disclosed for more reliable and convenient on-site drug testing. More particularly, but not by way of limitation, the presently disclosed and/or claimed inventive concept(s) relates to a portable spectrometer system having a test strip having a fluorescent indicator, a fluorimeter, and a mobile computing device capable of determining the identity of an unknown substance in the sample. |
| FILED | Friday, October 12, 2018 |
| APPL NO | 16/159352 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/255 (20130101) G01N 21/645 (20130101) Original (OR) Class G01N 21/6428 (20130101) G01N 2201/0221 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 11199691 | Vaziri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Rockefeller University (New York, New York) |
| ASSIGNEE(S) | The Rockefeller University (New York, New York) |
| INVENTOR(S) | Alipasha Vaziri (Greenwich, Connecticut); Tobias Noebauer (New York, New York); Oliver Skocek (Engelhartstetten, Austria) |
| ABSTRACT | An imaging signal extraction apparatus comprising: an interface; a processing device, the processing device operatively coupled to the interface; and a computer readable medium comprising instructions that, when executed by the processing device, perform operations comprising: a) generating a two-dimensional image from imaging information obtained from the interface, thereby estimating ballistic component of the imaging information; b) generating a three-dimensional image by remapping the two-dimensional image; c) identifying a candidate object in the three-dimensional image; d) obtaining an estimated spatial forward model of the candidate object by mapping the three-dimensional image of the candidate object with a point-spread-function associated with the imaging apparatus; e) obtaining background-corrected data by using the estimated spatial forward model of the candidate object and estimated temporal components; and f) iteratively updating the estimated spatial forward model and estimated temporal components until convergence is reached for the candidate object, thereby extracting the signal information. |
| FILED | Wednesday, October 07, 2020 |
| APPL NO | 17/065499 |
| ART UNIT | 2422 — Cable and Television |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/367 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Treasury (TREASURY)
| US 11198316 | Phillips et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WAVEFRONT TECHNOLOGY, INC. (Paramount, California) |
| ASSIGNEE(S) | WAVEFRONT TECHNOLOGY, INC. (Paramount, California) |
| INVENTOR(S) | Roger Winston Phillips (Santa Rosa, California); Christopher Chapman Rich (Rancho Palos Verdes, California); Joel Mikael Petersen (Valley Village, California) |
| ABSTRACT | A document, product, or package, such as a banknote, passport or the like comprises structures having dichroic effects that change color with viewing angle in both transmission and reflection. Such structures can be useful as security features that counter the ability to effectively use counterfeit documents, products, packages, etc. |
| FILED | Monday, February 03, 2020 |
| APPL NO | 16/780777 |
| ART UNIT | 3637 — Static Structures, Supports and Furniture |
| CURRENT CPC | Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 25/29 (20141001) B42D 25/45 (20141001) B42D 25/351 (20141001) B42D 25/355 (20141001) B42D 25/373 (20141001) Original (OR) Class B42D 25/378 (20141001) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11200186 | Fleming, Jr. et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Intel Corporation (Santa Clara, California) |
| ASSIGNEE(S) | Intel Corporation (Santa Clara, California) |
| INVENTOR(S) | Kermin E. Fleming, Jr. (Hudson, Massachusetts); Simon C. Steely, Jr. (Hudson, New Hampshire); Kent D. Glossop (Nashua, New Hampshire); Mitchell Diamond (Shrewsbury, Massachusetts); Benjamin Keen (Marlborough, Massachusetts); Dennis Bradford (Portland, Oregon); Fabrizio Petrini (Menlo Park, California); Barry Tannenbaum (Nashua, New Hampshire); Yongzhi Zhang (Wayland, Massachusetts) |
| ABSTRACT | Systems, methods, and apparatuses relating to operations in a configurable spatial accelerator are described. In one embodiment, a configurable spatial accelerator includes a first processing element that includes a configuration register within the first processing element to store a configuration value that causes the first processing element to perform an operation according to the configuration value, a plurality of input queues, an input controller to control enqueue and dequeue of values into the plurality of input queues according to the configuration value, a plurality of output queues, and an output controller to control enqueue and dequeue of values into the plurality of output queues according to the configuration value. |
| FILED | Saturday, June 30, 2018 |
| APPL NO | 16/024854 |
| ART UNIT | 2185 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30145 (20130101) G06F 13/4027 (20130101) Original (OR) Class G06F 15/7867 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11201608 | Galan |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Elias J. Galan (Baltimore, Maryland) |
| ASSIGNEE(S) | NORTHROP GRUMMAN SYSTEMS CORPORATION (Falls Church, Virginia) |
| INVENTOR(S) | Elias J. Galan (Baltimore, Maryland) |
| ABSTRACT | One example includes a superconducting latch system. The system includes a first input stage configured to receive a first input pulse and a second input stage configured to receive a second input pulse. The system also includes a storage loop configured to switch from a first state to a second state in response to receiving the first input pulse, and to switch from the second state to the first state in response to the second input pulse. The first state corresponds to no flux in the storage loop and the second state corresponds to a flux in the storage loop. The system further includes an output stage configured to generate an output pulse in the second state of the storage loop. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 16/857325 |
| ART UNIT | 2842 — Electrical Circuits and Systems |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/0356 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/223 (20130101) Pulse Technique H03K 3/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, December 14, 2021.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
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You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2021/details-patents-20210427.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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