FedInvent™ Patent Applications
Application Details for Thursday, February 10, 2022
This page was updated on Monday, February 14, 2022 at 10:14 PM GMT
Department of Health and Human Services (HHS)
| US 20220039648 | Draelos et al. |
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| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Draelos (Durham, North Carolina); Joseph Izatt (Durham, North Carolina); Anthony Kuo (Durham, North Carolina); Pablo Ortiz (Durham, North Carolina); Ryan McNabb (Durham, North Carolina) |
| ABSTRACT | Systems and methods for imaging a target feature of a subject based on the tracked positions of the subject and the target feature are disclosed. According to an aspect, a system includes a scanner configured to image a target feature of a subject. The system includes a mechanism configured to move the scanner. Further, the system includes a subject tracker configured to track positioning of the subject. The system includes a feature tracker configured to track positioning of the target feature. A controller is configured to control the mechanism to move the feature tracker to a position such that the feature tracker is operable to track a position of the target feature. The controller controls the mechanism to move the scanner to a position such that the scanner is operable to image the target feature based on the tracked position of the target feature by the feature tracker. |
| FILED | Wednesday, January 29, 2020 |
| APPL NO | 17/413996 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 3/12 (20130101) A61B 3/14 (20130101) A61B 3/0033 (20130101) A61B 3/102 (20130101) Original (OR) Class A61B 3/113 (20130101) A61B 3/117 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220039676 — TONOMETRY BASED BLOOD PRESSURE MEASUREMENTS USING A TWO-DIMENSIONAL FORCE SENSOR ARRAY
| US 20220039676 | Mehrotra et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sanjay Mehrotra (Winnetka, Illinois); Ilya Mikhelson (Wilmette, Illinois); Alan Varteres Sahakian (Northbrook, Illinois) |
| ABSTRACT | Representative methods, apparatus and systems are disclosed for blood pressure and other vital sign monitoring using arterial applanation tonometry, including ambulatory blood pressure and other vital sign monitoring. A representative system comprises a wearable apparatus. The various embodiments measure blood pressure and other vital sign monitoring using a plurality of pressure sensors of a pressure sensor array, with one or more of the pressure sensors 140 applanating an artery, such as a radial artery. In a first embodiment, a pressure sensor signal is utilized which has the highest cross-coherence with the signals of its nearest pressure sensor neighbors of the pressure sensor array. In a second embodiment, Kalman filtering is utilized for the pressure sensor signals from the pressure sensor array. |
| FILED | Monday, July 26, 2021 |
| APPL NO | 17/385216 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/02 (20130101) A61B 5/02108 (20130101) Original (OR) Class A61B 5/6824 (20130101) A61B 2562/0247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220039732 | Mahon et al. |
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| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bradford Mahon (Pittsburgh, Pennsylvania); Adnan Hirad (Rochester, New York) |
| ABSTRACT | A system is configured for receiving force data including at least one value indicating the amount of the force applied to the portion of the user and at least one value indicating a direction of the force applied to the portion of the user; obtaining mapping data specifying at least one relation between values of force applied to the portion of the user and changes in a functional responsiveness, functional and/or structural integrity, or both the functional responsiveness and the functional and/or structural integrity of the brain at one or more locations in the brain; estimating, based on the mapping data and the force data, an amount of force loading at one or more particular locations in the brain; and generating, based on the estimating, output data representing an amount of the damage to the brain at the one or more particular locations in the brain. |
| FILED | Thursday, August 05, 2021 |
| APPL NO | 17/395247 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0004 (20130101) A61B 5/0053 (20130101) A61B 5/746 (20130101) A61B 5/4064 (20130101) Original (OR) Class A61B 5/6803 (20130101) A61B 5/7264 (20130101) A61B 5/7275 (20130101) A61B 2562/0219 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220039753 | WU et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); Uinted States of America, as Represented by the Secretary, Department of Health and Human Services (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Min WU (Clarksville, Maryland); Mingliang CHEN (College Park, Maryland); Qiang ZHU (College Park, Maryland); Quanzeng WANG (Olney, Maryland) |
| ABSTRACT | An apparatus for vital sign extraction. The apparatus may receive a vital signal of a subject from a sensing device. The apparatus may also perform a preprocessing procedure on the vital signal via bandpass filtering and normalization to obtain a preprocessed signal. The apparatus may also perform a time-frequency analysis of the preprocessed signal, and estimate a heart rate of the subject from a dominant component of the preprocessed signal by finding location of a maximum spectral energy of the time-frequency analysis. In addition, the apparatus may identify guard components in the preprocessed signal in view of the dominant component, and derive a respiratory rate of the subject from a length of an interval between the dominant component and each of the guard components. |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 17/394269 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0004 (20130101) A61B 5/0816 (20130101) A61B 5/02416 (20130101) A61B 5/7225 (20130101) A61B 5/7228 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220039956 | Dupont et al. |
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| FUNDED BY |
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| APPLICANT(S) | Children`s Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pierre Dupont (Wellesley, Massachusetts); Karl D. Price (Brookline, Massachusetts); Gustavo Arnal (Boston, Massachusetts) |
| ABSTRACT | The present disclosure involves a system and method of use for delivering an interventional instrument, such as an artificial chordae tendineae (ACT) delivery instrument, into a beating heart. By delivering interventional instruments in a beating heart via the system described here, complex and invasive open heart procedures as well as cardiopulmonary bypass can be avoided, significantly reducing patient trauma and recovery time as well as operation time and complexity. The system disclosed includes an optical imaging system to provide the practitioner with visual imagery from the end of the system, and allow for real-time or near real-time imaging of tissue inside the beating heart (e.g., leaflet tissue). This provides for accurate verification of placement of the interventional instrument. In addition, the system includes a grasping mechanism, which allows the practitioner to hold tissue in position prior to placing the interventional instrument. |
| FILED | Monday, February 10, 2020 |
| APPL NO | 17/429107 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/06 (20130101) A61B 1/018 (20130101) A61B 17/3421 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/2457 (20130101) A61F 2/2466 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220039971 | Colvin et al. |
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| APPLICANT(S) | WillowWood Global LLC (Mount Sterling, Ohio) |
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| INVENTOR(S) | James M. Colvin (Hilliard, Ohio); Matthew M. Wernke (Tampa, Florida); Evandro M. Ficanha (Grove City, Ohio) |
| ABSTRACT | A prosthetic foot that includes a foot plate having a toe portion and a heel portion, a shank plate bonded to the foot plate along a seam that extends from the toe portion rearward toward the heel portion to terminate at an end, the shank plate separated from the foot plate forming a gap between the foot plate and shank plate extending rearward from the end of the seam; and an attachment structure attaching the foot plate to the shank plate, wherein the attachment structure includes fibers extending continuously through the shank plate, the gap, and the foot plate. In embodiments, the foot plate and shank plate are made of composite material and the attachment structure alternately extends through the seam and through a flexible material between the shank plate and the foot plate. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/509864 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/66 (20130101) Original (OR) Class A61F 2002/5053 (20130101) A61F 2002/6664 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040000 | Grubbs et al. |
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| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); The Regents of the University of California (Oakland, California); United States Government Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); The Regents of the University of California (Oakland, California); United States Government represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Robert H. Grubbs (South Pasadena, California); Marshall L. Stoller (San Francisco, California); Ying Han (Burlingame, California); Frank L. Brodie (Durham, North Carolina) |
| ABSTRACT | A surgical method of cataract fragmentation and extraction via microbubble cavitation is described. In particular, gas-filled microbubbles are injected into a lens capsule of a subject's eye, and cavitation of the microbubbles is activated by applied ultrasound energy. The ultrasound energy can be applied from an external device. The cavitation fragments cataract tissues without damaging other tissue, such as the lens capsule. Fragmented lens material is then aspirated from the lens capsule. The method can be used alone or in conjunction with other methods, such as phacoemulsification. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/509641 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/00745 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040110 | Liu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Velico Medical Inc. (Beverly, Massachusetts) |
| ASSIGNEE(S) | Velico Medical Inc. (Beverly, Massachusetts) |
| INVENTOR(S) | Qiyong Peter Liu (Newton, Massachusetts); Junqing Cui (West Roxbury, Massachusetts); Rud Karly Lucien (Lynn, Massachusetts); Ryan Carney (Hudson, New Hampshire); Jihae Sohn (Brighton, Massachusetts); Michelle Arya (Medford, Massachusetts) |
| ABSTRACT | A method of treatment of plasma with a physiologically compatible spray dry stable acidic substance (SDSAS) prior to or contemporaneously with spray drying of the plasma that results in greater recovery and greater long-term stabilization of the dried plasma proteins as compared to spray dried plasma that has not be subject to the formulation method of the present invention, as well as compostions related to plasma dried by the methods of the present invention. |
| FILED | Friday, October 22, 2021 |
| APPL NO | 17/508904 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/16 (20130101) A61K 9/1617 (20130101) A61K 9/1682 (20130101) Original (OR) Class A61K 9/1688 (20130101) A61K 35/16 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/06 (20130101) Drying Solid Materials or Objects by Removing Liquid Therefrom F26B 3/04 (20130101) F26B 3/06 (20130101) F26B 3/12 (20130101) F26B 5/04 (20130101) F26B 5/065 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040134 | Freeman et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Bruce A. Freeman (Pittsburgh, Pennsylvania); Carola Neumann (Pittsburgh, Pennsylvania); Francisco J. Schopfer (Pittsburgh, Pennsylvania) |
| ABSTRACT | A method comprising co-administering to a subject having cancer, suspected of having cancer, or at risk of developing cancer: a therapeutically effective amount of at least one compound (a) selected from (a)(i) a nitroalkene fatty acid, (a)(ii) an unsaturated fatty acid having an electron withdrawing group, a leaving group, and a carbon-carbon double bond disposed between the electron withdrawing group and the leaving group, (a)(iii) a thiolated nitro fatty acid, or (a)(iv) a dicarboxylic acid compound containing an electron withdrawing group; and a therapeutically effective amount of at least one anti-neoplastic agent (b), wherein the cancer is a cancer with hereditary etiology of defects in DNA repair genes, a cancer with a high rate of spontaneous genomic instability, a cancer that responds well to DNA damaging agent(s), or a cancer that responds well to a combination of DNA damaging agent(s) with immunotherapy. |
| FILED | Thursday, November 14, 2019 |
| APPL NO | 17/290963 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/201 (20130101) Original (OR) Class A61K 31/231 (20130101) A61K 31/454 (20130101) A61K 31/502 (20130101) A61K 31/704 (20130101) A61K 31/4184 (20130101) A61K 31/4745 (20130101) A61K 31/5025 (20130101) A61K 33/243 (20190101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 205/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040136 | FOSTER et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Rochester (Rochester, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David FOSTER (Rochester, New York); Megan L. FALSETTA WOOD (Rochester, New York); Richard P. PHIPPS (Rochester, New York) |
| ABSTRACT | The present invention relates to methods of treating vulvovaginal disorders, including female reproductive tract irritation (such as pain and pruritus) or/and inflammation. |
| FILED | Wednesday, October 02, 2019 |
| APPL NO | 17/280638 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0034 (20130101) A61K 31/202 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040143 | Thumbikat et al. |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Praveen Thumbikat (Chicago, Illinois); Anthony J. Schaeffer (Hinsdale, Illinois) |
| ABSTRACT | Provided herein are compositions and methods for the treatment of conditions such as benign prostatic hyperplasia (BPH), Lower Urinary Tract Symptoms (LUTS), chronic prostatitis (CP) and/or chronic pelvic pain syndrome (CPPS). In particular, provided herein are combination therapies comprising a mast cell inhibitor and a histamine receptor antagonist. |
| FILED | Thursday, August 05, 2021 |
| APPL NO | 17/395153 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) Original (OR) Class A61K 31/495 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040145 | Sampson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Axial Therapeutics, Inc. (Woburn, Massachusetts); California Institute of Technology (Pasadena, California) |
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| INVENTOR(S) | Timothy Sampson (Los Angeles, California); Sarkis Mazmanian (Glendale, California); Anthony Stewart Campbell (Framingham, Massachusetts) |
| ABSTRACT | The present disclosure provides methods and compositions for the prevention, amelioration, or alleviation of one or more neurological disorders associated with microbially-induced amyloid formation. Methods of inhibiting, ameliorating, reducing the likelihood, delaying the onset of, treating, or preventing an amyloid disorder are disclosed. Methods of identifying compounds capable of inhibiting the formation of microbially-induced amyloid fibrils are disclosed. |
| FILED | Wednesday, September 08, 2021 |
| APPL NO | 17/447178 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/05 (20130101) A61K 31/192 (20130101) A61K 31/216 (20130101) A61K 31/235 (20130101) A61K 31/353 (20130101) Original (OR) Class A61K 31/465 (20130101) A61K 31/522 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040146 | Horzempa et al. |
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| FUNDED BY |
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| APPLICANT(S) | WEST LIBERTY UNIVERSITY (West Liberty, West Virginia); UNIVERSITY OF MISSISSIPPI (University, Mississippi) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph A. Horzempa (Pittsburgh, Pennsylvania); Elliot M. Collins (Crooksville, Ohio); Juan Francisco Leon (Gainesville, Florida) |
| ABSTRACT | A pharmaceutical composition is provided that comprises an effective amount of dillapiole or a derivative thereof, and a pharmaceutically-acceptable vehicle, carrier, or excipient. Methods of treating a bacterial infection are also described and include administering an effective amount of dillapiole or a derivative thereof to a subject in need of such treatment. Methods of reducing bacterial virulence are further described and include contacting a bacterium, such as a F. tularensis or A. baumannii bacterium, with an effective amount of dillapiole or a derivative thereof. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/396223 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/09 (20130101) A61K 31/36 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040147 | Crossley et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven W. M. Crossley (Kensington, California); Guanghu Tong (San Diego, California); Michael Lambrecht (Burlingame, California); Hannah Burdge (La Jolla, California); Ryan Shenvi (San Diego, California) |
| ABSTRACT | The present disclosure relates to concise processes for making (−)-picrotoxinin (1, PXN) and 5-methyl-picrotoxinin (20, 5MePXN), and to 5MePXN, its pharmaceutical compositions, and its method of use for inhibiting GABAA receptor. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 16/947560 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/365 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040160 | Hodge et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | James W. Hodge (Kensington, Maryland); Sofia R. Gameiro (North Bethesda, Maryland) |
| ABSTRACT | A method of reducing cancer cell growth, a method of increasing sensitivity of cancer cells to CTL mediated killing, and a method of increasing sensitivity of cancer cells to NK mediated killing are provided. The methods comprise treating cancer cells with a combination of a HDAC inhibitor and immunotherapy. |
| FILED | Monday, August 16, 2021 |
| APPL NO | 17/402751 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/167 (20130101) A61K 31/4166 (20130101) A61K 31/4406 (20130101) Original (OR) Class A61K 39/235 (20130101) A61K 39/275 (20130101) A61K 39/001102 (20180801) A61K 39/001152 (20180801) A61K 39/001182 (20180801) A61K 39/001194 (20180801) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040177 | Wu et al. |
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| FUNDED BY |
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| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dianqing Wu (Cheshire, Connecticut); Qianying Yuan (New Haven, Connecticut); Abdul Basit (Cincinnati, Ohio); Wenwen Tang (North Haven, Connecticut) |
| ABSTRACT | The invention includes methods of preventing or treating acute lung injury using a MAP3K2/MAP3K3 inhibitor. The invention further comprises compositions, and kits comprising compositions useful within the invention. |
| FILED | Friday, October 08, 2021 |
| APPL NO | 17/497191 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 9/0073 (20130101) A61K 31/506 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040207 | SOLWAY et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois); THE UNITED STATES OF AMERICA as represented by THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland); PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts); IIT RESEARCH INSTITUTE (Chicago, Illinois); BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (Boston, Massachusetts); REGENTS OF THE UNIVESITY OF MINNESOTA (Minneapolis, Massachusetts); THE TRUSTEES OF PURDUE UNIVERSITY (West Lafayette,, Indiana) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois); The United States of America as Represented by the Secretary Department of Health and Human Services (Bethesda, Maryland); President and Fellows of Harvard College (Cambridge, Massachusetts); IIT Research Institute (Chicago, Illinois); Beth Israel Deaconess Medical Center, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Julian SOLWAY (, None); Nickolai DULIN (, None); Marsha ROSNER (, None); Gokhan MUTLU (, None); Diane LUCI (, None); David MALONEY (, None); Chan Young PARK (, None); Jeffrey FREDBERG (, None); David MCCORMICK (, None); Ramaswamy KRISHNAN (, None) |
| ABSTRACT | Disclosed herein is a class of molecules termed remodilins that inhibit serum response factor (SRF). By inhibiting SRF, a number of downstream pathways can be targeted. The remodilins can be used to treat glaucoma, inhibit tumor cell growth, inhibit tumor metastasis, inhibit hypoxia-induced response, and/or reduce cellular metabolism. |
| FILED | Thursday, April 02, 2020 |
| APPL NO | 17/594090 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/18 (20130101) A61K 31/63 (20130101) A61K 31/635 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Acyclic or Carbocyclic Compounds C07C 311/16 (20130101) C07C 311/21 (20130101) C07C 2601/02 (20170501) C07C 2601/04 (20170501) C07C 2601/08 (20170501) C07C 2601/14 (20170501) C07C 2601/16 (20170501) Heterocyclic Compounds C07D 207/48 (20130101) C07D 211/34 (20130101) C07D 211/96 (20130101) C07D 239/42 (20130101) C07D 241/04 (20130101) C07D 265/30 (20130101) C07D 277/52 (20130101) C07D 279/12 (20130101) C07D 295/13 (20130101) C07D 295/26 (20130101) C07D 309/14 (20130101) C07D 401/12 (20130101) C07D 471/04 (20130101) C07D 487/08 (20130101) C07D 491/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040208 | Bergeson et al. |
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| FUNDED BY |
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| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Susan E. Bergeson (Lubbock, Texas); Peter Syapin (Camarillo, California); Ted W. Reid (Lubbock, Texas); Mayank Shashtrl (Lubbock, Texas); Phat Tran (Lubbock, Texas) |
| ABSTRACT | A method of treating Alcohol Use Disorder (AUD), Substance Use Disorder (SUD), tobacco use, pain, or proinflammatory disorders comprising: providing a subject with an effective amount of a modified tetracycline or derivative thereof to ameliorate or eliminate the AUD, SUD, tobacco use, pain, or proinflammatory disorder, and wherein the modified tetracycline or derivative thereof has reduced binding to a microbial ribosome and has the formula wherein R1 is acetyl, R2 is OH or acetyl, R3 is acetyl, R4 is H or acetyl, and R5 is acetyl. |
| FILED | Thursday, June 13, 2019 |
| APPL NO | 16/973896 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/65 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040236 | Chen |
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| FUNDED BY |
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| APPLICANT(S) | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bo Chen (New York, New York) |
| ABSTRACT | The present invention provides methods and compositions for inducing differentiation of Müller glial cells into rod photoreceptors through a two-step process of inducing Müller glial cell proliferation by increasing WNT signaling effectors in the Müller glial cell and then directed differentiation into a rod photoreceptor through activation of rod-specific photoreceptor genes. The methods and compositions are useful in a method of treating vision loss or impairment due to photoreceptor loss. The present invention also provides methods for treating vision loss or impairment in a subject comprising (a) administering to the subject a therapeutically effective amount of a Müller glial (MG) cell proliferation agent; and (b) a period of time after the administering of step (a), administering to the subject a therapeutically effective amount of a MG cell differentiation agent. |
| FILED | Friday, April 05, 2019 |
| APPL NO | 17/045256 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/30 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/06 (20180101) Peptides C07K 14/47 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0622 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040242 | STRANDWITZ et al. |
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| FUNDED BY |
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| APPLICANT(S) | Holobiome, Inc. (South Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip STRANDWITZ (Medford, Massachusetts); Kim LEWIS (Newton, Massachusetts) |
| ABSTRACT | The present disclosure relates to methods of treating at least one symptom of a mental disorder or disease of the central nervous system in a subject by modulating the amount of GABA produced in the subject's gut. The present disclosure also relates to methods of culturing the bacterial strain new bacterial strains. Also disclosed are methods of identifying bacterial strains capable of producing GABA, and engineering strains to produce GABA. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/396330 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) A61K 35/742 (20130101) Original (OR) Class A61K 35/745 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/18 (20180101) A61P 25/22 (20180101) A61P 25/24 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0008 (20130101) C12N 9/0069 (20130101) C12N 9/78 (20130101) C12N 9/88 (20130101) C12N 9/1096 (20130101) Enzymes C12Y 102/01019 (20130101) C12Y 113/12001 (20130101) C12Y 206/01082 (20130101) C12Y 305/03011 (20130101) C12Y 401/01015 (20130101) C12Y 401/01017 (20130101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040255 | Ghadiri et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Reza M. Ghadiri (San Diego, California); Luke J. Leman (Encinitas, California); Poshen B. Chen (San Diego, California); Yannan Zhao (La Jolla, California); Ali Torkamani (San Diego, California); Audrey Black (San Diego, California) |
| ABSTRACT | The present invention provides methods for remodeling gut microbiome to a desired state. The invention also provides in vitro screening platform for identifying novel agents that can remodel dysfunctional gut microbiome. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 17/280660 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/12 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) C12Q 1/689 (20130101) C12Q 2600/136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040263 | List |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | H. Lee Moffitt Cancer Center and Research Institute, Inc. (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alan F. List (Tampa, Florida) |
| ABSTRACT | Disclosed herein is a companion diagnostic to predict efficacy of combination lenalidomide and erythropoietin treatment in patients with a erythropoietin (Epo)-refractory, Lower Risk (LR) Non-deletion 5q [Del(5q)] myelodysplastic syndrome (MDS). The method involves assaying erythroid precursors from a biological sample from the subject for a CD45 isoform profile, and treating the subject with a combination of lenalidomide and erythropoietin if the erythroid precursors have a predominance of large CD45RA and CD45RB isoforms compared to small CD45RO isoform. |
| FILED | Tuesday, March 02, 2021 |
| APPL NO | 17/189664 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/454 (20130101) A61K 38/1816 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/06 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/106 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56966 (20130101) G01N 33/57407 (20130101) G01N 2333/70582 (20130101) G01N 2333/70589 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040275 | DISIS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Mary L. DISIS (Renton, Washington); Denise Cecil (Shoreline, Washington); Meredith Slota (Seattle, Washington) |
| ABSTRACT | The compositions described herein include an epitope of a peptide that may elicit an immune response in a subject following administration. The compositions may comprise nucleic acids. The compositions may comprise peptides. The methods described herein include administering a composition comprising an epitope of a peptide to a subject in need thereof. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/451607 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/00115 (20180801) A61K 39/001103 (20180801) A61K 39/001106 (20180801) A61K 39/001129 (20180801) A61K 39/001152 (20180801) A61K 48/00 (20130101) A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/572 (20130101) Peptides C07K 14/71 (20130101) C07K 14/705 (20130101) C07K 14/4702 (20130101) C07K 14/70567 (20130101) C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/104 (20130101) Enzymes C12Y 203/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040276 | Moon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James J. Moon (Ann Arbor, Michigan); Rui Kuai (Ann Arbor, Michigan); Anna A. Schwendeman (Ann Arbor, Michigan); Jutaek Nam (Ann Arbor, Michigan) |
| ABSTRACT | The present invention relates to nanoparticles complexed with biomacromolecule agents configured for treating, preventing or ameliorating various types of disorders, and methods of synthesizing the same. In particular, the present invention is directed to compositions comprising nanoparticles (e.g., synthetic high density lipoprotein (sHDL)) carrying biomacromolecule agents (e.g., nucleic acid, peptides, glycolipids, etc.), methods for synthesizing such nanoparticles, as well as systems and methods utilizing such nanoparticles (e.g., in diagnostic and/or therapeutic settings). |
| FILED | Thursday, October 14, 2021 |
| APPL NO | 17/501576 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/127 (20130101) A61K 31/712 (20130101) A61K 31/713 (20130101) A61K 31/7088 (20130101) A61K 39/0011 (20130101) Original (OR) Class A61K 39/00111 (20180801) A61K 39/001106 (20180801) A61K 39/001132 (20180801) A61K 39/001151 (20180801) A61K 39/001156 (20180801) A61K 39/001157 (20180801) A61K 39/001162 (20180801) A61K 39/001164 (20180801) A61K 39/001166 (20180801) A61K 39/001176 (20180801) A61K 39/001181 (20180801) A61K 39/001182 (20180801) A61K 39/001184 (20180801) A61K 39/001186 (20180801) A61K 39/001188 (20180801) A61K 39/001189 (20180801) A61K 39/001191 (20180801) A61K 39/001192 (20180801) A61K 39/001193 (20180801) A61K 39/001194 (20180801) A61K 39/001195 (20180801) A61K 39/001197 (20180801) A61K 45/06 (20130101) A61K 47/554 (20170801) A61K 47/6917 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) C12N 2310/14 (20130101) C12N 2310/3515 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040285 | Weissman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania); ACUITAS THERAPEUTICS, INC. (Vancouver, Canada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Drew Weissman (Wynnewood, Pennsylvania); Norbert Pardi (Philadelphia, Pennsylvania); Ying Tam (Vancouver, Canada); Michael J. Hope (Vancouver, Canada) |
| ABSTRACT | The present invention relates to compositions and methods for inducing an adaptive immune response in a subject. In certain embodiments, the present invention provides a composition comprising a nucleoside-modified nucleic acid molecule encoding an antigen, adjuvant, or a combination thereof. For example, in certain embodiments, the composition comprises a vaccine comprising a nucleoside-modified nucleic acid molecule encoding an antigen, adjuvant, or a combination thereof. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/371261 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/127 (20130101) A61K 31/712 (20130101) A61K 31/7115 (20130101) A61K 39/002 (20130101) A61K 39/02 (20130101) A61K 39/0011 (20130101) A61K 39/12 (20130101) Original (OR) Class A61K 2039/51 (20130101) A61K 2039/55555 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/16 (20180101) A61P 31/18 (20180101) A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 219/08 (20130101) Heterocyclic Compounds C07D 295/13 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040286 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Linling He (San Diego, California); Jiang Zhu (San Diego, California); Anshul Chaudhary (La Jolla, California); Ian Wilson (La Jolla, California) |
| ABSTRACT | The present invention provides novel engineered Ebolavirus GP proteins and polypeptides, as well as scaffolded vaccine compositions that display the engineered proteins. The invention also provides methods of using such engineered Ebolavirus GP proteins and vaccine compositions in various therapeutic applications, e.g., for preventing or treating Ebolavirus infections. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397340 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class Peptides C07K 14/473 (20130101) C07K 2317/34 (20130101) C07K 2319/735 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2760/14134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040288 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Bethesda, Maryland) |
| ASSIGNEE(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC (Bethesda, Maryland) |
| INVENTOR(S) | Baoming Jiang (Duluth, Georgia); Yuhuan Wang (Liburn, Georgia) |
| ABSTRACT | Attenuated G9P[6] rotavirus is disclosed herein. In some embodiments, pharmaceutical compositions are disclosed that include an attenuated G9P[6] rotavirus, or a component thereof. These compositions can be used to induce an immune response, such as a protective immune response, to a rotavirus. The compositions can be used as vaccines, such as for children (infants), for example in a prime boost strategy. |
| FILED | Friday, October 29, 2021 |
| APPL NO | 17/515074 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 39/15 (20130101) Original (OR) Class A61K 39/39 (20130101) A61K 2039/5252 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2720/12021 (20130101) C12N 2720/12034 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040290 | PERMAR et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sallie PERMAR (Durham, North Carolina); Joel COLLIER (Durham, North Carolina); Kevin O. SAUNDERS (Durham, North Carolina); Chelsea FRIES (Durham, North Carolina); Fouda Amou'ou Genevieve GINY (Durham, North Carolina) |
| ABSTRACT | The technology provides immunogenic compositions comprising HIV-1 envelopes in supramolecular nanofiber complexes, which may also comprise a T-cell helper epitopes, and methods of using these compositions for induction of immune responses. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 17/279033 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) Original (OR) Class A61K 2039/6031 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040309 | Kohane et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Children's Medical Center Corporation (Boston, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Daniel S. Kohane (Newton, Massachusetts); Rong Yang (Cambridge, Massachusetts); Lily Yun Lin (Austin, Texas) |
| ABSTRACT | The present invention provides compositions and methods for delivery of therapeutic agents across an barrier. The compositions include a therapeutic agent (e.g., antimicrobial agent, antibiotic, or anesthetic agent), a permeation enhancer which increases the flux of the therapeutic agent across the barrier, and a matrix forming agent. The matrix forming agent forms a gel at a suitable gelation temperature and rheological properties for use in drug delivery, and in some cases, the gelation temperature and rheological properties are not significantly changed from those of the composition without the permeation enhancer. The invention also provides a matrix forming agent and compositions thereof. Such compositions are particularly useful in the treatment of otitis media. Methods of treatment, methods of delivery, and kits for the compositions described herein are also provided. |
| FILED | Friday, July 23, 2021 |
| APPL NO | 17/383494 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/0046 (20130101) A61K 31/407 (20130101) A61K 31/424 (20130101) A61K 31/431 (20130101) A61K 31/445 (20130101) A61K 31/496 (20130101) A61K 31/573 (20130101) A61K 31/4709 (20130101) A61K 31/5383 (20130101) A61K 38/12 (20130101) A61K 45/06 (20130101) A61K 47/06 (20130101) A61K 47/10 (20130101) A61K 47/12 (20130101) A61K 47/20 (20130101) A61K 47/22 (20130101) A61K 47/26 (20130101) A61K 47/34 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/16 (20180101) A61P 31/04 (20180101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/3355 (20130101) C08G 79/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040326 | PAN |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhuo-Hua PAN (Troy, Michigan) |
| ABSTRACT | Microbial type rhodopsins, such as the light-gated cation-selective membrane channel, channelrhodopsin-2 (Chop2/ChR2) or the ion pump halorhodopsin (HaloR) are expressed in retinal ganglion cells upon transduction using recombinant AAV vectors. Selective targeting of these transgenes for expression in discrete subcellular regions or sites is achieved by including a sorting motif in the vector that can target either the central area or surround (off-center) area of these cells. Nucleic acid molecules comprising nucleotide sequences encoding such rhodopsins and sorting motifs and their use in methods of differential expression of the transgene are disclosed. These compositions and methods provide significant improvements for restoring visual perception and various aspects of vision, particular in patients with retinal disease. |
| FILED | Monday, March 08, 2021 |
| APPL NO | 17/195288 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Peptides C07K 14/705 (20130101) C07K 14/4702 (20130101) C07K 2319/01 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8616 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040334 | Schmitt et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MDI Biological Laboratory (Salisbury Cove, Maine) |
| ASSIGNEE(S) | MDI Biological Laboratory (Salisbury Cove, Maine) |
| INVENTOR(S) | Roland Schmitt (Salisbury Cove, Maine); Anette Melk (Salisbury Cove, Maine); Vera Wulfmeyer (Salisbury Cove, Maine); Maxine Swallow (Salisbury Cove, Maine) |
| ABSTRACT | A method and system for screening candidate substances or compositions thereof, where mammalian cells containing a stain or detectable marker are introduced into the yolk sac of a fertilized egg, embryo, or larvae of a transparent and/or translucent fish model. The method and system may also be employed to identify detectable marker genes, marker proteins, or marker metabolites in the transplanted mammalian cells, where the marker may indicate, e.g., cellular senescence, non-senescence, excessive or abnormal proliferation, damaged DNA. Methods of treating a subject suffering from a disease, disorder, or condition resulting from cellular senescence, excessive or abnormal proliferation, or damaged DNA using the candidate substances or compositions thereof are provided. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/391239 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040335 | Jain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sanjay K. Jain (Baltimore, Maryland); Alvaro A. Ordonez (Baltimore, Maryland); Camilo A. Ruiz-Bedoya (Baltimore, Maryland) |
| ABSTRACT | The present invention provides positron emitter radiolabeled versions of PABA, metabolites and derivatives, with good radiochemical yield, high specific activity, high chemical and radiochemical purity and having excellent characteristics for PET imaging. The inventive composition and methods provide high quality dynamic images of the kidneys while reducing the radiation exposure. The short biological half-life of PABA, added to the short physical half-life of positron emitters such as 11C will also benefit patients that require multiple renography assessments in a short period of time. |
| FILED | Wednesday, September 11, 2019 |
| APPL NO | 17/275658 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0402 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040337 | ZEGLIS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| ASSIGNEE(S) | Memorial Sloan Kettering Cancer Center (New York, New York) |
| INVENTOR(S) | Brian ZEGLIS (New York, New York); Jason LEWIS (New York, New York); Thomas REINER (New York, New York); Jacob Lee HOUGHTON (New York, New York); Jan-Philip MEYER (New York, New York); Christian BRAND (New York, New York) |
| ABSTRACT | Described herein are Tz/TCO-based pretargeting strategies using an Al[18F]-NOTA-labeled tetrazine radioligand. This imaging strategy enables delineation of cancer at earlier time points compared to other imaging strategies and further decreases the radiation dose to healthy tissues compared to directly labeled antibodies. Al-based 18F imaging of small molecules, such as tetrazine, has not been previously achieved due to the decomposition of tetrazine during radiofluorination. Radiofluorination is advantageous over other radiolabeling methods because, in addition to having a shorter half-life, 18F is more readily available to produce and therefore integrated into hospital workflows. |
| FILED | Wednesday, September 01, 2021 |
| APPL NO | 17/464472 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6897 (20170801) A61K 51/0453 (20130101) A61K 51/0482 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040410 | Cappello et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PHARMAJET INC. (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chris Cappello (Golden, Colorado); Matt Wixey (Golden, Colorado); John W. Bingham (Golden, Colorado) |
| ABSTRACT | A needle-free injection device suitable for delivering a therapeutic substance into the intradermal space of a patient. The needle-free injection device includes a first handle positioned to pivot between an open position and a closed position, a main spring, and a hammer engaged with the main spring. The needle-free injection device also includes a return sleeve engaged with the hammer when the first handle is in the open position. The return sleeve is disengaged with the hammer when the first handle is in the closed position. Needle-free injection systems and methods of operating a needle-free injection device are also disclosed. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/509364 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/20 (20130101) A61M 5/30 (20130101) Original (OR) Class A61M 2005/2013 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040479 | Lo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Yi-Kai Lo (Los Angeles, California); Wentai Liu (Los Angeles, California); Victor R. Edgerton (Los Angeles, California); Chih-Wei Chang (Los Angeles, California) |
| ABSTRACT | A wireless implant and associated system for motor function recovery after spinal cord injury, and more particularly a multi-channel wireless implant with small package size. The wireless implant can further be used in various medical applications, such as retinal prostheses, gastrointestinal implant, vagus nerve stimulation, and cortical neuromodulation. The system also includes a method and its implementation to acquire the impedance model of the electrode-tissue interface of the implant. |
| FILED | Friday, August 27, 2021 |
| APPL NO | 17/459468 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/08 (20130101) A61N 1/0551 (20130101) A61N 1/3787 (20130101) A61N 1/36003 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040496 | Adaikkan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chinnakkaruppan Adaikkan (Somerville, Massachusetts); Li-Huei Tsai (Cambridge, Massachusetts) |
| ABSTRACT | Devices, systems, and methods for treating dementia or Alzheimer's disease in a subject in need thereof. In one example, chronic visual stimuli having a frequency of about 30 Hz to about 50 Hz, and more specifically about 40 Hz, are non-invasively delivered to the subject to entrain gamma oscillations in multiple brain regions of the subject, including the prefrontal cortex (PFC) and the hippocampus. The entrained gamma oscillations modulate neuronal activity across multiple brain regions (e.g., facilitate functional binding of neural networks at low gamma frequencies) to induce various neuroprotective effects (e.g., amelioration of amyloid plaques and tau hyper-phosphorylation) and reduce neurodegeneration. Neuronal activity mediated by the chronic visual stimuli reduces an immune response in microglia and ameliorates aberrantly modified genes and proteins involved in membrane trafficking, intracellular transport, synaptic function, neuroinflammation and DNA damage response. Behavior modification including enhanced learning and memory is observed. |
| FILED | Tuesday, March 30, 2021 |
| APPL NO | 17/217789 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/0618 (20130101) A61N 5/0622 (20130101) Original (OR) Class A61N 5/1001 (20130101) A61N 2005/0626 (20130101) A61N 2005/0652 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040498 | GREENE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark GREENE (Penn Valley, Pennsylvania); Hongtao ZHANG (Paoli, Pennsylvania); Hiromichi TSUCHIYA (Philadelphia, Pennsylvania); Yasuhiro NAGAI (Philadelphia, Pennsylvania); Lian LAM (Philadelphia, Pennsylvania); Aaron RUNKLE (Philadelphia, Pennsylvania); Jeffrey DREBIN (Bryn Mawr, Pennsylvania); Mei Qing JI (Voorhees, New Jersey) |
| ABSTRACT | Disclosed herein are methods of increasing response to radiation therapy in subjects afflicted with cancer. In some embodiments, the method comprises reducing the ability of an immune suppressor cell (e.g., MDSC) to migrate to the microenvironment of the cancer. In some embodiments, the method further comprises suppressing the migration of the immune suppressor cell to a non-malignant cell and/or suppressing the malignant transformation of the non-malignant cells. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/375459 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/10 (20130101) Original (OR) Class A61N 2005/1098 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040508 | SREBRIC et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jelena SREBRIC (Takoma Park, Maryland); Avery LAYNE (Upper Marlboro, Maryland); Nicholas W. MATTISE (Washington, District of Columbia); Shengwei ZHU (Ellicott City, Maryland); Sebastian ROMO (College Park, Maryland); Lingzhe WANG (Greenbelt, Maryland) |
| ABSTRACT | Filtered, clean air can be provided via a personalized airflow to a user, to reduce inhalation of unwanted particles, bioaerosoles, and the like, while providing greater comfort than passive PPE. Various systems and methods are disclosed herein, for filtering and cleaning air via a smart, wearable device. For example, a headset in accordance with this disclosure can detect unwanted particulate matter, harmful compounds, bioaerosols, and other ambient conditions, and dynamically adjust an airflow to form an airshield that is distributed over a user's nose and mouth so as to reduce inhalation of contaminated air by as much as 70%. Various embodiments may utilize filters, disinfection modules, pressure sensors, movement sensors, ambient sensors, and contaminant sensors housed within wearable, portable devices. |
| FILED | Thursday, August 05, 2021 |
| APPL NO | 17/395399 |
| CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 7/10 (20130101) A62B 18/003 (20130101) A62B 18/006 (20130101) A62B 18/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041543 | BLAGG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF KANSAS (Lawrence, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian S.J. BLAGG (Lawrence, Kansas); Rick T. DOBROWSKY (Olathe, Kansas); Mercy ANYIKA (Lawrence, Kansas) |
| ABSTRACT | Provided herein are compounds of the formulas: wherein: n, X2, R3, R3′, R4, R4′, R5, R5′, R6, and R6′ are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, these compounds may be used for the treatment of diseases, including diabetic peripheral neuropathy or cancer. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/375882 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/18 (20130101) Original (OR) Class C07C 2601/08 (20170501) C07C 2601/14 (20170501) C07C 2601/16 (20170501) Heterocyclic Compounds C07D 307/20 (20130101) C07D 309/10 (20130101) C07D 311/08 (20130101) C07D 311/16 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 15/203 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041606 | Lindsley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Craig W. Lindsley (Brentwood, Tennessee); P. Jeffrey Conn (Nashville, Tennessee); Julie L. Engers (Brentwood, Tennessee); Alison R. Gregro (Mount Juliet, Tennessee); Madeline F. Long (Nashville, Tennessee) |
| ABSTRACT | Described are substituted fused bicyclic pyridinone and pyrimidinone carboxamide positive allosteric modulators of muscarinic acetylcholine receptor M1 (mAChR M1), pharmaceutical compositions including the compounds, and methods of using the compounds and compositions for treating neurological disorders, psychiatric disorders, or a combination thereof. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/386876 |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) C07D 487/04 (20130101) Original (OR) Class C07D 491/048 (20130101) C07D 495/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041618 | CUI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | XINYAN CUI (Wexford, Pennsylvania); BIN CAO (Berwyn, Pennsylvania) |
| ABSTRACT | A method of forming a compound having the formula: includes the reaction: n the presence of a base comprising teat-butyl lithium, lithium diisopropylamide, sodium hydroxide, potassium hydroxide, lithium hydroxide, a potassium alkoxide or a sodium alkoxide to achieve a yield of at least 90%, wherein X is a halo atom selected from the group consisting of Cl, Br and I. |
| FILED | Tuesday, October 26, 2021 |
| APPL NO | 17/510819 |
| CURRENT CPC | Heterocyclic Compounds C07D 495/04 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2/58 (20130101) C08F 28/06 (20130101) C08F 2400/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041619 | Gibbs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| ASSIGNEE(S) | OREGON HEALTH and SCIENCE UNIVERSITY (Portland, Oregon) |
| INVENTOR(S) | Summer L. Gibbs (West Linn, Oregon); Lei G. Wang (Portland, Oregon); Connor W. Barth (Portland, Oregon) |
| ABSTRACT | Provided are near-infrared nerve-sparing fluorescent compounds, compositions comprising them, and methods of their use in medical procedures. |
| FILED | Wednesday, September 11, 2019 |
| APPL NO | 17/275608 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0071 (20130101) Heterocyclic Compounds C07D 498/04 (20130101) Original (OR) Class Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/06 (20130101) C09K 2211/1033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041627 | XUE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Fengtian XUE (Potomac, Maryland); Yan SHU (Clarksville, Maryland); Yong AI (Baltimore, Maryland) |
| ABSTRACT | The invention relates to prodrugs of anti-cancer and anti-autoimmune diseases therapeutic agents, and methods of making and use thereof. |
| FILED | Wednesday, December 04, 2019 |
| APPL NO | 17/311216 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/025 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041629 | WANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | XAVIER UNIVERSITY OF LOUISIANA (New Orleans, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Guangdi WANG (New Orleans, Louisiana); Madhusoodanan MOTTAMAL (New Orleans, Louisiana); Borui KANG (New Orleans, Louisiana) |
| ABSTRACT | The present disclosure relates to compounds that act as antagonists via binding to the ER ligand binding domain non-covalently or covalently, or act as both antagonists and ER protein degraders, and the synthesis of the same. Further, the present disclosure teaches the utilization of such compounds in a treatment for proliferative diseases, including cancer, particularly breast cancer, and especially ER+ breast cancer. |
| FILED | Wednesday, September 11, 2019 |
| APPL NO | 17/275860 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041650 | THOMAS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seth R. THOMAS (Durham, North Carolina); Frederick W. PORTER (Durham, North Carolina); Matthew A. TYSON (Durham, North Carolina); Lakshmi Sravya KOMPALLI (Durham, North Carolina) |
| ABSTRACT | The invention is directed to methods for purifying recombinant proteins, e.g. HIV-1 envelope trimers and/or nanoparticles, wherein the methods do not use an affinity step. |
| FILED | Tuesday, December 03, 2019 |
| APPL NO | 17/297931 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/20 (20130101) Peptides C07K 1/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041655 | HUNT et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Agenus Inc. (Lexington, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Donald F. HUNT (Lexington, Massachusetts); Jeffrey SHABANOWITZ (Lexington, Massachusetts); Jennifer COTTINE HITCHCOCK (Lexington, Massachusetts); Ann M. ENGLISH (Lexington, Massachusetts); Andrew NORRIS (Lexington, Massachusetts); Victor H. ENGELHARD (Lexington, Massachusetts); Mark COBBOLD (Lexington, Massachusetts); Kara L. CUMMINGS (Lexington, Massachusetts); Angela L. AMBAKHUTWALA (Lexington, Massachusetts); Rebecca C. OBENG (Lexington, Massachusetts); Jie QIAN (Lexington, Massachusetts) |
| ABSTRACT | A set of phosphorylated peptides are presented by HLA A*0101, A*0201, A*0301, B*4402, B*2705, B*1402, and el B*0702 on the surface of melanoma cells. They have the potential to (a) stimulate an immune response to the cancer, (b) to function as immunotherapeutics in adoptive T-cell therapy or as a vaccine, (c) to facilitate antibody recognition of the tumor boundaries in surgical pathology samples, and (d) act as biomarkers for early detection of the disease. Phosphorylated peptides are also presented for other cancers. |
| FILED | Thursday, February 18, 2021 |
| APPL NO | 17/178525 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 39/0011 (20130101) Peptides C07K 7/06 (20130101) Original (OR) Class C07K 7/08 (20130101) C07K 14/70539 (20130101) C07K 16/18 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5743 (20130101) G01N 33/6893 (20130101) G01N 33/57492 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041659 | SHUSTA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric V. SHUSTA (Madison, Wisconsin); Benjamin UMLAUF (Madison, Wisconsin); Brantley HERRIN (Atlanta, Georgia); Paul CLARK (Madison, Wisconsin); John KUO (Austin, Texas) |
| ABSTRACT | The present disclosure provides isolated polypeptides comprising variable lymphocyte receptors that specifically bind the brain extracellular matrix, compositions, and methods of use. Methods of using the variable lymphocyte receptors for the detection and treatment of disease or injury, specifically, for example, cancers including glioblastoma are provided. |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 17/414581 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041660 | Gleghorn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jason P. Gleghorn (Lincoln University, Pennsylvania); Catherine A. Fromen (Wilmington, Delaware); Katherine M. Nelson (Elkton, Maryland) |
| ASSIGNEE(S) | University of Delaware (Newark, Delaware) |
| INVENTOR(S) | Jason P. Gleghorn (Lincoln University, Pennsylvania); Catherine A. Fromen (Wilmington, Delaware); Katherine M. Nelson (Elkton, Maryland) |
| ABSTRACT | A composition for sequestering a pathogen, for example, viral particles of a target virus in the respiratory tract of a subject is provided. The composition comprises an effective amount of sequestering particles having a protein binding agent on the surface of the sequestering particles. The protein binding agent binds a pathogenic surface protein, for example, capsid protein on the surface of the viral particles. The sequestering particles and the target pathogen, for example, viral particles, form aggregates. Also provided is the use of the composition for sequestering a target pathogen, for example, viral particles of a target virus, in the respiratory tract of a subject. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/396006 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/005 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041667 | Kapiloff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The University of Miami (Miami, Florida); The United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael S. Kapiloff (Los Altos, California); Jeffrey L. Goldberg (Menlo Park, California) |
| ABSTRACT | Nervous system trauma and neurodegeneration including in optic neuropathies are treated by administration of an effective dose of a PDE4D3 displacing agent to promote neurite extension, neuroprotection and recovery. In some embodiments the neurons are optic neurons, including without limitation retinal ganglion cells (RGCs). A cAMP signaling compartment restricted by mAKAPα-anchored PDE4D3 directly regulates neuronal phenotype, and can be molecularly manipulated with therapeutic effect. |
| FILED | Wednesday, November 13, 2019 |
| APPL NO | 17/290174 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/4702 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041668 | Gallucci et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Randle M. Gallucci (Edmond, Oklahoma); Kaitlin N. CALHOUN (Greeley, Colorado) |
| ABSTRACT | A method of treating a skin wound in a subject by administering at least one inhibitor of C-C chemokine receptor type-3 (CCR3) and/or at least one inhibitor of a CCR3 ligand, thereby causing increased activity of keratinocytes adjacent the skin wound, wherein epithelialization of the skin wound is promoted, and wherein the increased activity of keratinocytes is at least one of (1) increased proliferation of the keratinocytes and (2) increased migration of the keratinocytes adjacent the skin wound. The skin wound may be a chronic wound or an acute wound for example. The inhibitor may be, for example, an antibody or antibody fragment, a small molecule, or an siRNA able to inhibit expression of CCR3. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/396235 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/02 (20180101) Peptides C07K 14/4703 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041669 | Miller et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sean James Miller (Baltimore, Maryland); Jeffrey D. Rothstein (Catonsville, Maryland) |
| ABSTRACT | Described are methods of treating or preventing dendritic spine loss in a subject. The methods include a step of administering to a subject having or at risk of having dendritic spine loss a pharmaceutical composition. In addition, pharmaceutical compositions are described comprises an agent selected from the group comprising a salt, solvate, or stereoisomer of a norrin protein or functional part thereof; a vector expressing the norrin protein or functional part thereof; or a combination thereof, and a pharmaceutically acceptable carrier. |
| FILED | Wednesday, September 18, 2019 |
| APPL NO | 17/277676 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 14/475 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041673 | LOEB et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (Urbana, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey A. LOEB (Chicago, Illinois); Fei SONG (Troy, Michigan) |
| ABSTRACT | A method and kit for treating a neurodegenerative disease or central nervous system disorder in a subject using a GlyB4 fusion protein is provided, as is a kit containing the same. |
| FILED | Thursday, January 02, 2020 |
| APPL NO | 17/415156 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) A61P 25/28 (20180101) Peptides C07K 14/82 (20130101) C07K 14/4756 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041675 | Mendoza et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Juan Luis Mendoza (Redwood City, California); Kenan Christopher Garcia (Menlo Park, California) |
| ABSTRACT | Compositions and methods are provided relating to Type III interferons. |
| FILED | Wednesday, October 27, 2021 |
| APPL NO | 17/512456 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7088 (20130101) A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/20 (20180101) A61P 35/00 (20180101) Peptides C07K 14/555 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041677 | DONAHOE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE GENERAL HOSPITAL CORPORATION (Boston, Massachusetts); MASSACHUSETTS EYE AND EAR INFIRMARY (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patricia K. DONAHOE (Boston, Massachusetts); Demetrios VAVVAS (Boston, Massachusetts); David PEPIN (Somerville, Massachusetts); Mien Van HOANG (Braintree, Massachusetts) |
| ABSTRACT | The present invention relates to modified recombinant human MIS protein which has improved cleavage and increased bioactivity and increased potency as compared to wild-type human MIS protein. Other aspects of the invention relate to methods to prevent and treat cancers, such as cancers that express the MIS receptor type II (MISRII) by administering to a subject a composition comprising a recombinant human MIS protein. Another aspect of the present invention relates to methods to lower plasma androgen levels in a subject, and/or for the treatment of a subject with a disease characterized by excess androgen. Another aspect provides pharmaceutical compositions and kits and methods for use comprising a recombinant human MIS protein. Another aspect of the present invention relates to methods to decrease the dose of a chemotherapeutic agent by administering the chemotherapeutic agent with the recombinant MIS protein that lowers the effective dose of the chemotherapeutic agent. |
| FILED | Thursday, June 17, 2021 |
| APPL NO | 17/350223 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/416 (20130101) A61K 38/00 (20130101) A61K 45/06 (20130101) Peptides C07K 14/575 (20130101) Original (OR) Class C07K 14/765 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041697 | SIGURDSSON |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NEW YORK UNIVERSITY (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Einar M. SIGURDSSON (Scarsdale, New York) |
| ABSTRACT | The present invention relates to antibody-based molecules that are capable of preferentially and selectively binding to the C-terminal di-phosphorylated {p}Ser396/{p}Ser404 Tau peptide as well as to the {p}Ser404 Tau peptide and the non-phosphorylated Tau peptide, but does not bind to the {p}Ser396 Tau peptide. Such antibody-based molecules are useful to detect pathological Tau protein conformer if present in a biological sample, especially in conjunction with the diagnosis and/or treatment of Alzheimer's disease or other Tauopathy, and thus provide a diagnostic for Alzheimer's disease and other Tau pathologies. The antibody-based molecules of the present invention also have particular utility as prophylactic and therapeutic molecules for the treatment and/or prevention of Alzheimer's disease and related tauopathies. |
| FILED | Tuesday, December 10, 2019 |
| APPL NO | 17/312854 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041698 | LUK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kelvin C. LUK (Philadelphia, Pennsylvania); Virginia M.Y. LEE (Philadelphia, Pennsylvania); John Q. TROJANOWSKI (Philadelphia, Pennsylvania); Kurt R. BRUNDEN (Media, Pennsylvania); Dustin COVELL (Philadelphia, Pennsylvania) |
| ABSTRACT | The present disclosure provides monoclonal antibodies that bind α-Synuclein. In certain aspects, the antibodies preferentially bind to α-Synuclein fibrils over α-Synuclein monomer. In other aspects, the invention comprises a method of treating α-Synucleopathic disease in a subject, comprising administering any of the antibodies of the invention to the subject. In yet other aspects, the invention comprises methods of detecting α-Synuclein fibrils using any of the antibodies of the invention. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/509970 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/395 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/16 (20180101) Peptides C07K 16/18 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041726 | Freeman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts); Emory University (Atlanta, Georgia); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gordon J. Freeman (Brookline, Massachusetts); Rafi Ahmed (Atlanta, Georgia); Arlene H. Sharpe (Brookline, Massachusetts); Masao Hashimoto (Decatur, Georgia); Hyun T. Jin (Atlanta, Georgia) |
| ABSTRACT | The present invention relates to methods of reducing liver PD-1-expressing CD8+ T cells using PD-1 Fc fusion proteins that bind Fc receptors, as well as diagnostic, prognostic, therapeutic methods and compositions related thereto. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 17/407941 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 41/0038 (20130101) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/16 (20180101) A61P 35/00 (20180101) Peptides C07K 14/70503 (20130101) C07K 16/2818 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041818 | Harth et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eva M. Harth (Nashville, Tennessee); David M. Stevens (Nashville, Tennessee) |
| ABSTRACT | Disclosed herein are crosslinked polycarbonates, composition thereof and methods thereof. The crosslinked polycarbonates can be prepared from allyl or epoxy polycarbonates. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Wednesday, March 17, 2021 |
| APPL NO | 17/204715 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/19 (20130101) A61K 9/5146 (20130101) A61K 9/5192 (20130101) A61K 47/34 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/06 (20130101) A61L 31/16 (20130101) A61L 31/146 (20130101) A61L 2300/412 (20130101) A61L 2300/416 (20130101) A61L 2400/12 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/34 (20130101) C08G 59/66 (20130101) C08G 59/504 (20130101) C08G 64/42 (20130101) C08G 64/0216 (20130101) C08G 64/0241 (20130101) C08G 64/0291 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 3/246 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/37 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041886 | Jiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | Shaoyi Jiang (Seattle, Washington); Xiaojie Lin (Seattle, Washington); Jonathan Himmelfarb (Seattle, Washington); Buddy D. Ratner (Seattle, Washington) |
| ABSTRACT | Zwitterionic carboxybetaine copolymers and their use in coatings to impart non-fouling and functionality to surfaces, particularly surfaces of blood-contacting medical devices. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 17/435654 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 29/06 (20130101) A61L 29/041 (20130101) A61L 29/085 (20130101) A61L 29/141 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/28 (20130101) C08J 2333/26 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 133/26 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041928 | BELL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTELLIGENT MATERIAL SOLUTIONS, INC. (Princeton, New Jersey); LEIDEN UNIVERSITY MEDICAL CENTER (Leiden, Netherlands); U.S.A , AS REPRESENTED BY THE SECRETARY, OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | INTELLIGENT MATERIAL SOLUTIONS, INC. (Princeton, New Jersey); LEIDEN UNIVERSITY MEDICAL CENTER (Leiden, Netherlands); U.S.A , AS REPRESENTED BY THE SECRETARY, OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Howard Y. BELL (Princeton, New Jersey); Joshua E. Collins (Wallingford, Pennsylvania); Paul L.A.M. Corstjens (Leiderdorp, Netherlands); Sukwan Handali (Norcross, Georgia); Hans J. Tanke (Rijnsburg, Netherlands) |
| ABSTRACT | New methods and assays for multiplexed detection of analytes using phosphors that are uniform in morphology, size, and composition based on their unique optical lifetime signatures are described herein. The described assays and methods can be used for imaging or detection of multiple unique chemical or biological markers simultaneously in a single assay readout. |
| FILED | Wednesday, July 07, 2021 |
| APPL NO | 17/369012 |
| CURRENT CPC | Books; Book Covers; Loose Leaves; Printed Matter Characterised by Identification or Security Features; Printed Matter of Special Format or Style Not Otherwise Provided For; Devices for Use Therewith and Not Otherwise Provided For; Movable-strip Writing or Reading Apparatus B42D 15/00 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/36 (20200101) C01F 17/265 (20200101) C01F 17/288 (20200101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/10 (20130101) C01P 2004/20 (20130101) C01P 2004/32 (20130101) C01P 2004/52 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7773 (20130101) C09K 11/7791 (20130101) Original (OR) Class Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 7/08 (20130101) C30B 7/14 (20130101) C30B 29/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041984 | GILL |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Saar GILL (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods of generating sources of immune cells and/or stem cells for cell therapy. One aspect of the invention includes a method of generating an immune cell to be modified into an immune cell comprising a chimeric antigen receptor (CAR). Another aspect of the invention includes a method of generating cells, such as immune cells and/or stem cells, for autologous or allogeneic cell therapy. Also included are methods and pharmaceutical compositions comprising the cells for adoptive therapy and treating a condition, such as an autoimmune disease or cancer. |
| FILED | Tuesday, March 02, 2021 |
| APPL NO | 17/189970 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/7051 (20130101) C07K 16/30 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) Original (OR) Class C12N 2506/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041985 | WARD et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GPB SCIENTIFIC, INC. (Richmond, Virginia); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| ASSIGNEE(S) | GPB SCIENTIFIC, INC. (Richmond, Virginia); UNIVERSITY OF MARYLAND, BALTIMORE (Baltimore, Maryland); THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Anthony WARD (Rancho Santa Fe, California); Roberto CAMPOS-GONZALEZ (Carlsbad, California); Alison SKELLEY (Riverside, California); Khushroo GANDHI (Palo Alto, California); Curt CIVIN (Baltimore, Maryland); James C. STURM (Princeton, New Jersey); Michael GRISHAM (Richmond, Virginia) |
| ABSTRACT | The present invention is directed to the use of microfluidics in the preparation of cells and compositions for therapeutic uses. |
| FILED | Monday, September 06, 2021 |
| APPL NO | 17/467385 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502753 (20130101) B01L 3/502761 (20130101) B01L 2200/0652 (20130101) B01L 2300/0816 (20130101) B01L 2300/0864 (20130101) B01L 2400/086 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0087 (20130101) C12N 5/0636 (20130101) Original (OR) Class C12N 2531/00 (20130101) C12N 2533/54 (20130101) C12N 2533/74 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041988 | Russ et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Holger A. Russ (Denver, Colorado); Stephan A. Ramos (Aurora, Colorado); Antonio Jimeno (Greenwood Village, Colorado); John Jason Morton (Thornton, Colorado) |
| ABSTRACT | The disclosed technology includes methods, systems, and devices for generating patient-specific functional thymic epithelial progenitor (TEP) cells. In some implementations, a method may include generating iPSCs from HSC; causing differentiation of the iPSC into thymic epithelial progenitor (TEP) cells, generating thymic epithelial cells by transplantation of the TEP cells into a host, wherein the TEP cells may differentiate into mature functional thymic epithelial cells (TECs). In some implementations, a system may include a cell population of patient specific cells, a population of iPSCs, a culture system for differentiating the iPSCs into a population of patient-specific TEP cells for transfer to a host or the patient to allow the TEP cells to differentiate into mature, functional TEC. |
| FILED | Tuesday, October 26, 2021 |
| APPL NO | 17/511228 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/26 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) Original (OR) Class C12N 5/0696 (20130101) C12N 2501/15 (20130101) C12N 2501/16 (20130101) C12N 2501/41 (20130101) C12N 2501/115 (20130101) C12N 2501/155 (20130101) C12N 2501/385 (20130101) C12N 2501/415 (20130101) C12N 2506/11 (20130101) C12N 2506/45 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041990 | Lee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gabsang Lee (Baltimore, Maryland); Kathryn Wagner (Baltimore, Maryland); Congshan Sun (Baltimore, Maryland); InYoung Choi (Baltimore, Maryland); Ho Tae Lim (Baltimore, Maryland); Peter Andersen (Battimore, Maryland) |
| ABSTRACT | Provided herein are, inter alia, are methods, compositions and kits for producing populations of myogenic progenitor cells, and compositions comprising the cell populations derived thereof. Also included are methods and compositions for treating or preventing a muscle disease or disorder in a subject (e.g., Duchenne muscular dystrophy (DMD). |
| FILED | Friday, April 03, 2020 |
| APPL NO | 17/599431 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0658 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041994 | Neal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James Neal (San Mateo, California); Calvin Jay Kuo (Palo Alto, California) |
| ABSTRACT | Functional in vitro assays are provided for determining patient specific responsiveness to immunotherapy agents within a clinically actionable time frame. |
| FILED | Friday, October 22, 2021 |
| APPL NO | 17/508474 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/39558 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/2818 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 5/0693 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5011 (20130101) G01N 33/5047 (20130101) G01N 33/57484 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042001 | STONE |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Everett STONE (Austin, Texas) |
| ABSTRACT | Disclosed herein are compositions related to conjugated polypeptides with MTA/ADO-degrading enzyme activity. The conjugated polypeptides are engineered to allow for maximal conjugation while maintaining catalytic activities. Also disclosed are nucleic acids, expression vectors, and host cells related to the conjugated polypeptides. Further disclosed are methods of using the pharmaceutical formulations comprising above to treat cancer. |
| FILED | Wednesday, January 06, 2021 |
| APPL NO | 17/427519 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/60 (20170801) Peptides C07K 16/2818 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1077 (20130101) Original (OR) Class Enzymes C12Y 204/02028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042006 | Yamamoto et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (MINNEAPOLIS, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Masato Yamamoto (Minneapolis, Minnesota); Yoshiaki Miura (Roseville, Minnesota) |
| ABSTRACT | Described herein is a method that generally includes infecting a host cell with a rescue adenovirus, wherein the rescue adenovirus genome comprises a loxP site and encodes at least one marker, and wherein the host cell comprises a library of polynucleotides that complement the adenovirus genome marker and encode a detectable polypeptide; incubating the infected host cell under conditions effective to permit recombination between the adenovirus genome and one or more of the library polynucleotides and the production of recombinant adenovirus particles comprising at least on detectable polypeptide; and detecting the at least one detectable polypeptide. Also described are adenovirus libraries constructed using such a method. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/509798 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 15/1034 (20130101) Original (OR) Class C12N 15/1037 (20130101) C12N 2710/10043 (20130101) C12N 2710/10071 (20130101) C12N 2800/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042015 | Khvorova et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anastasia Khvorova (Westborough, Massachusetts); Annabelle Biscans (Cambridge, Massachusetts) |
| ABSTRACT | Provided herein are conjugated oligonucleotides that are characterized by efficient and specific tissue distribution with enhanced in vivo silencing efficacy. |
| FILED | Friday, July 16, 2021 |
| APPL NO | 17/377632 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/542 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/11 (20130101) C12N 2310/315 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042019 | BATEY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (Denver, Colorado); INSCRIPTA INC. (Boulder, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert BATEY (Boulder, Colorado); Roman S. IWASAKI CORDERO (Boulder, Colorado); Andrew GARST (Boulder, Colorado) |
| ABSTRACT | Provided herein are single guide RNAs (sgRNAs) that comprise aptamer sequences and related compositions and methods. Also provided herein are methods of selecting inducible sgRNAs that comprise aptamer sequences. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/375808 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 15/115 (20130101) Original (OR) Class C12N 2310/16 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042046 | KONG |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wei KONG (Phoenix, Arizona) |
| ABSTRACT | The present disclosure relates to genetically modified strains of Salmonella, engineered to be tumor navigating, self-eradicating, and armed with TRAIL to trigger tumor cell apoptosis. Also provided herein are methods of producing and methods of using such genetically modified Salmonella strains to treat cancer. |
| FILED | Thursday, February 20, 2020 |
| APPL NO | 17/433222 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/74 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/87 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/42 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042048 | Saha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Krishanu Saha (Middleton, Wisconsin); Christian Matthew Capitini (Madison, Wisconsin); Katherine Paige Mueller (Madison, Wisconsin); Nicole Jenine Piscopo (Madison, Wisconsin); Amritava Das (Madison, Wisconsin); Matthew Hull Forsberg (Madison, Wisconsin); Louise Armie Saraspe (Madison, Wisconsin) |
| ABSTRACT | Described herein are non-viral, ex vivo methods of site-specifically inserting a transgene containing a chimeric antigen receptor (CAR) gene into a T cell genome by introducing into a population of unmodified T cells a Cas9 ribonucleoprotein (RNP) and a non-viral double-stranded homology-directed repair (HDR) template, to provide genome-edited T cells. The Cas9 ribonucleoprotein includes a Cas9 protein and a guide RNA that directs double stranded DNA cleavage of a cleavage site in a T cell expressed gene. The non-viral double-stranded HDR template comprises the synthetic DNA sequence flanked by homology arms that are complementary to sequences on both sides of the cleavage site in the T cell expressed gene. The transgene is specifically integrated into the cleavage site of the T cell expressed gene created by the Cas9 RNP in the genome-edited T cells, and the cells are then cultured. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 17/407606 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2501/599 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042056 | Cordero et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Radames JB Cordero (Baltimore, Maryland); Arturo Casadevall (Baltimore, Maryland); Raghav Vij (Pune, India) |
| ABSTRACT | Described are methods including cell wall-associated melanin extraction and extracting melanin from microbes producing extracellular vesicles comprising melanin. Further described are composition comprising melanin, melanin coated articles and methods of coating an article. Uses of melanin in methods of heat generation and microwave radiation protection are also described. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 17/415694 |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 17/182 (20130101) Original (OR) Class Protection Against X-radiation, Gamma Radiation, Corpuscular Radiation or Particle Bombardment; Treating Radioactively Contaminated Material; Decontamination Arrangements Therefor G21F 1/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042100 | ZHANG et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | WILLIAM MARSH RICE UNIVERSITY (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Yu ZHANG (Houston, Texas); Xi CHEN (Houston, Texas); Omid VEISEH (Houston, Texas); Peng DAI (Houston, Texas); Kerou ZHANG (Houston, Texas) |
| ABSTRACT | Provided herein are methods for quantifying foreign cell-free DNA (cfDNA) via SNP profiling of low-volume blood sample. The methods allow for monitoring the status of organ transplant rejection through analysis of small volumes of patient capillary blood samples collected non-invasively with fingersticks or other devices. The methods also allow for guiding the dosage of immunosuppressant and for preparing for a new organ transplant in case of imminent organ failure. |
| FILED | Thursday, December 05, 2019 |
| APPL NO | 17/311102 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6827 (20130101) C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042113 | Totary-Jain et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Hana Totary-Jain (Wesley Chapel, Florida); Ezinne Francess Mong (Tampa, Florida) |
| ABSTRACT | Provided herein are methods of measuring C19MC miRNA amount and/or expression in a post-natal cell and/or tissue. Provided herein are methods of measuring CpG methylation of the upstream C19MC miRNA promoter region in a post-natal cell and/or tissue. Also provided herein are methods of treating a cell, population thereof, and/or a subject in need thereof by administering a C19MC miRNA inhibitor or CRISPR to suppress the expression of specific miRNA within the C19MC or the entire C19MC cluster, population thereof, and/or the subject in need thereof. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/509648 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 2310/20 (20170501) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/154 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042506 | Wikswo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Ronald S. Reiserer (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); Dmitry A. Markov (Nashville, Tennessee); Clayton M. Britt (Franklin, Kentucky) |
| ABSTRACT | A push-pull micropump includes one or more pairs of channels configured to transfer one or more fluids, each channel pair having an aspiration channel and an injection channel; and an actuator configured to engage the one or more pairs of channels, wherein the actuator comprises a plurality of rolling members and a driving member configured such that when the driving member rotates, the plurality of rolling members rolls along the one or more pairs of channels to cause individually the one or more fluids to transfer through each channel pair simultaneously at different flowrates or the same flowrate, depending upon actuated lengths of the aspiration and injection channels of each channel pair, wherein an actuated length of a channel is defined by a length of the channel along which the plurality of rolling members rolls during a full rotation of the driving member. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/505940 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/12 (20130101) F04B 43/0054 (20130101) F04B 43/0072 (20130101) F04B 43/1253 (20130101) F04B 43/1269 (20130101) Original (OR) Class F04B 43/1292 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042905 | Salaita et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Khalid Salaita (Atlanta, Georgia); Yixiao Dong (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to non-naturally occurring light reflecting or color changing materials comprising a segmented array of flexible polymers, wherein the segmented array of flexible polymers comprise photonic crystal lattices embedded therein, wherein the segmented array of flexible polymers are themselves embedded within an elastic supporting polymer that maintains a near constant size during chromatic shifting of the photonic crystal lattices. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397318 |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 3/36 (20130101) C08K 7/24 (20130101) C08K 2003/2275 (20130101) C08K 2201/011 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042911 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chen He (Chicago, Illinois); David J. Weinberg (San Diego, California); Emily A. Weiss (Evanston, Illinois); Jeremiah Yoonsung Kim (Glenview, Illinois); Chen Wang (Evanston, Illinois); Andrew Lee (Evanston, Illinois) |
| ABSTRACT | The present technology is directed to the nanoparticles for use as molecular environmental sensors. The nanoparticles comprise a photoluminescence core and a plurality of ligands bound to the core and forming a quencher permeable ligand shell. The ligands comprise a reactive or charged moiety capable of being modulated between a first stand and a second state, and the proportion of ligands in each state determine the permeability of the ligand shell to a photoluminescence quencher. |
| FILED | Tuesday, October 19, 2021 |
| APPL NO | 17/505392 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 21/21 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) Original (OR) Class G01N 21/6489 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042992 | Altin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (Phoenix, Arizona); ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona) |
| ASSIGNEE(S) | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (PHOENIX, Arizona); ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona) |
| INVENTOR(S) | John Altin (Flagstaff, Arizona); Jason Ladner (Flagstaff, Arizona) |
| ABSTRACT | The present disclosure includes a multiplexed peptide assay to generate an epitope-resolved view of antibody reactivity across all human coronaviruses (CoVs). PepSeq accurately classifies SARS-CoV-2 exposure status and reveals epitopes across the Spike and Nucleocapsid proteins. Two of these represent recurrent reactivities to conserved, functionally-important sites in the S2 subunit of Spike, regions that we show are also targeted for the endemic CoVs in pre-pandemic controls. At one of these sites, we demonstrate that the SARS-CoV-2 response strongly and recurrently cross-reacts with the endemic virus hCoV-OC43. The disclosed epitope-resolved analysis reveals new CoV targets for the development of diagnostics, vaccines and therapeutics, including a site that may have broad neutralizing potential. |
| FILED | Thursday, August 05, 2021 |
| APPL NO | 17/395330 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/215 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2770/20034 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) Original (OR) Class G01N 2333/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044399 | An et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hongyu An (St. Louis, Missouri); Chunwei Ying (St. Louis, Missouri); Yasheng Chen (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Hongyu An (St. Louis, Missouri); Chunwei Ying (St. Louis, Missouri); Yasheng Chen (St. Louis, Missouri) |
| ABSTRACT | Systems and methods for deep-learning-based T1-enhanced selection of linear attenuation coefficients (DL-TESLA) for PET/MR attenuation are described. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397982 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 3/40 (20130101) G06T 7/0012 (20130101) Original (OR) Class G06T 2207/10088 (20130101) G06T 2207/30016 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044452 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ge Wang (Loudonville, New York); Weiwen Wu (Troy, New York); Wenxiang Cong (Albany, New York); Hengyong Yu (Westford, Massachusetts) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Ge Wang (Loudonville, New York); Weiwen Wu (Troy, New York); Wenxiang Cong (Albany, New York); Hengyong YU (Westford, Massachusetts) |
| ABSTRACT | Generally, there is provided a hybrid image reconstruction system. The hybrid image reconstruction system includes a deep learning stage and a compressed sensing stage. The deep learning stage is configured to receive an input data set that includes measured tomographic data and to produce a deep learning stage output. The deep learning stage includes a mapping circuitry, and at least one artificial neural network. The mapping circuitry is configured to map image domain data to a tomographic data domain. The compressed sensing stage is configured to receive the deep learning stage output and to provide refined image data as output. |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 17/393922 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 11/005 (20130101) Original (OR) Class G06T 2210/41 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044453 | Hong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kyungpyo Hong (Rego Park, New York); Daniel Kim (Naperville, Illinois) |
| ABSTRACT | An imaging system includes a sensor configured to receive imaging data, where the imaging data comprises k-space data from a magnetic resonance imaging (MRI) scan of a patient. The imaging system also includes a processor operatively coupled to the sensor and configured to identify a degree of interaction between measured points of the k-space data located at a radius from a center of k-space. The processor is also configured to determine, based at least in part on the degree of interaction between the measured points, density weights for a density compensation filter. The processor is also configured to apply the density compensation filter to the k-space data to generate filtered k-space data. The processor is further configured to generate an MRI image of the patient based at least in part on the filtered k-space data. |
| FILED | Tuesday, August 03, 2021 |
| APPL NO | 17/393061 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/4824 (20130101) G01R 33/5608 (20130101) Image Data Processing or Generation, in General G06T 11/006 (20130101) Original (OR) Class G06T 11/008 (20130101) G06T 2210/41 (20130101) G06T 2211/421 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044809 | Bihorac et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Azra Bihorac (Gainesville, Florida); Tyler J. Loftus (Gainesville, Florida); Tezcan Ozrazgat Baslanti (Gainesville, Florida); Parisa Rashidi (Gainesville, Florida); Benjamin P. Shickel (Alachua, Florida) |
| ABSTRACT | Methods, apparatus, systems, and computer program products for providing patient predictions are provided in various embodiments. Responsive to receiving an indication of initiation of a patient interaction, a model for the patient is initiated by an assessment computing entity. The model has been trained using machine learning and the model is configured to generate a prediction for the patient. The prediction comprises at least one of an acuity score or a mortality prediction. Responsive to identifying a prediction trigger, the assessment computing entity updates the model for the patient based at least in part on medical data corresponding to the patient. The assessment computing entity generates the prediction using the updated deep learning model. The assessment computing entity provides at least a portion of the prediction such that the at least a portion of the prediction may be used to update an electronic health record corresponding to the patient and/or provided to a clinician for review. |
| FILED | Friday, February 21, 2020 |
| APPL NO | 17/309975 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/30 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20220040463 | Frye et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clint D. Frye (Livermore, California); Mihail Bora (Livermore, California); Adam M. Conway (Livermore, California); Devin Joseph Funaro (Livermore, California); Paulius Vytautas Grivickas (Livermore, California); David L. Hall (San Ramon, California); Lars F. Voss (Livermore, California) |
| ABSTRACT | A product includes an elongated carbon-containing pillar having a bottom and a tip opposite the bottom. The width of the pillar measured 1 nm below the tip is less than 700 nm. A method includes masking a carbon-containing single crystal for defining masked regions and unmasked regions on the single crystal. The method also includes performing a plasma etch for removing portions of the unmasked regions of the single crystal, thereby defining a pillar in each unmasked region, and performing a chemical etch on the pillars at a temperature between 1200° C. and 1600° C. for selectively reducing a width of each pillar. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 16/987121 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0023 (20130101) A61M 2037/0053 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 1/008 (20130101) B81B 2201/055 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040596 | RESTIVO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (AIKEN, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MICHAEL L. RESTIVO (AIKEN, South Carolina); MICHAEL R. POIRIER (EVANS, Georgia); FERNANDO F. FONDEUR (NORTH AUGUSTA, South Carolina); SAMUEL D. FINK (AIKEN, South Carolina) |
| ABSTRACT | Centrifugal contactors that can be used for mixing or separating materials are described. The contactors include a sensing system including a communications fiber within the shaft of the contactors and access ports providing access from the communications fiber to the mixing/separating zone of the contactor. The sensing system can be utilized during operation of the contactor and can provide for detailed and accurate on-line characterization of a protocol, as well as process control and system modification as necessary during operation. |
| FILED | Wednesday, August 05, 2020 |
| APPL NO | 16/985894 |
| CURRENT CPC | Separation B01D 11/048 (20130101) Original (OR) Class Centrifuges B04B 1/02 (20130101) B04B 11/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040639 | Sant et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Gaurav Sant (Los Angeles, California); Erika Callagon La Plante (Los Angeles, California); Jingbo Wang (Los Angeles, California); David Jassby (Los Angeles, California); Dante Simonetti (Los Angeles, California); Abdulaziz Alturki (Los Angeles, California) |
| ABSTRACT | Provided herein are methods of removing carbon dioxide from an aqueous stream or gaseous stream by: contacting the gaseous stream comprising carbon dioxide, when present, with an aqueous solution comprising ions capable of forming an insoluble carbonate salt; contacting the aqueous solution comprising carbon dioxide with an electroactive mesh that induces its alkalinization thereby forcing the precipitation of a carbonate solid from the solution and thereby the removal of dissolved inorganic carbon by electrolysis; and removing the precipitated carbonate solids from the solution, or the surface of the mesh where they may deposit. Also provided herein are flow-through electrolytic reactors comprising an intake device in fluid connection with a rotating cylinder comprising an electroactive mesh, and a scraping device and/or liquid-spray based device for separating a solid from the mesh surface. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 17/408236 |
| CURRENT CPC | Separation B01D 53/62 (20130101) B01D 53/78 (20130101) B01D 53/965 (20130101) Original (OR) Class B01D 2251/402 (20130101) B01D 2251/404 (20130101) B01D 2252/1035 (20130101) B01D 2257/504 (20130101) B01D 2258/06 (20130101) B01D 2258/025 (20130101) B01D 2258/0233 (20130101) B01D 2258/0283 (20130101) Non-metallic Elements; Compounds Thereof; C01B 13/36 (20130101) C01B 32/60 (20170801) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4618 (20130101) C02F 1/46109 (20130101) C02F 2001/4619 (20130101) C02F 2001/46133 (20130101) C02F 2001/46161 (20130101) C02F 2001/46171 (20130101) C02F 2103/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040656 | Bromberg et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MAAT Energy Company (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leslie Bromberg (Sharon, Massachusetts); Kim-Chinh Tran (Cambridge, Massachusetts); Jorj Ian Owen (Dulles, Virginia); Jonathan Whitlow (Melbourne Beach, Florida) |
| ABSTRACT | Devices and methods for reducing the specific energy required to reform or pyrolyze reactants in plasmas operating at high flow rates and high pressures are presented. These systems and methods include 1) introducing electrons and/or easily ionized materials to a plasma reactor, 2) increasing turbulence and swirl velocity of the flows of feed gases to have improved mixing in a plasma reactor, and 3) reducing slippage from a plasma reactor system. Such plasma systems may allow plasma reactors to operate at lower temperatures, higher pressure, with improved plasma ignition, increased throughput and improved energy efficiency. In preferred embodiments, the plasma reactors are used to produce hydrogen and carbon monoxide, hydrogen and carbon, or carbon monoxide through reforming and pyrolysis reactions. Preferred feedstocks include methane, carbon dioxide, and other hydrocarbons. |
| FILED | Tuesday, February 25, 2020 |
| APPL NO | 17/433131 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 4/001 (20130101) B01J 6/008 (20130101) Original (OR) Class B01J 8/0278 (20130101) B01J 19/088 (20130101) B01J 19/126 (20130101) B01J 19/129 (20130101) B01J 19/2405 (20130101) B01J 2219/00159 (20130101) B01J 2219/0847 (20130101) B01J 2219/0849 (20130101) B01J 2219/0892 (20130101) B01J 2219/0898 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/26 (20130101) C01B 3/382 (20130101) C01B 2203/0205 (20130101) C01B 2203/0277 (20130101) C01B 2203/0861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040666 | Wilson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Steven Wilson (Phoenix, Arizona); Christopher Muhich (Phoenix, Arizona); Ellen B. Stechel (Albuquerque, New Mexico); Ivan Ermanoski (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Steven Wilson (Phoenix, Arizona); Christopher Muhich (Phoenix, Arizona); Ellen B. Stechel (Albuquerque, New Mexico); Ivan Ermanoski (Tempe, Arizona) |
| ABSTRACT | A material for separating and pumping oxygen is disclosed. The material is a zeolite doped with a chemical element having an electron density of between 30 kJ/mol and 150 kJ/mol. The material is configured for controllable oxygen desorption between 150° C. and 300° C. and pumping the released oxygen into an area having an ambient pressure of less than 100 pascals. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/396238 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/18 (20130101) Original (OR) Class B01J 20/0207 (20130101) B01J 20/0211 (20130101) B01J 20/0218 (20130101) B01J 20/0222 (20130101) B01J 20/0225 (20130101) B01J 20/0248 (20130101) B01J 20/0251 (20130101) B01J 20/0292 (20130101) B01J 20/2808 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220040677 — MULTIMETALLIC CATALYSTS FOR METHANATION OF CARBON DIOXIDE AND DRY REFORMING OF METHANE
| US 20220040677 | Ferrandon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Magali Ferrandon (Steger, Illinois); Gokhan Celik (Clarendon Hills, Illinois); Massimiliano Delferro (Chicago, Illinois) |
| ABSTRACT | Processes for forming multimetallic catalysts by grafting nickel precusors to metal oxide supports. Dry reforming reaction catalysts having nickel and promotors grafted to metal oxides supports. Methanation reaction catalysts having nickel and promotors grafted to metal oxides supports. |
| FILED | Tuesday, August 04, 2020 |
| APPL NO | 16/984836 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 21/10 (20130101) B01J 23/10 (20130101) B01J 23/22 (20130101) B01J 23/745 (20130101) B01J 23/755 (20130101) Original (OR) Class B01J 37/18 (20130101) B01J 37/086 (20130101) B01J 37/0203 (20130101) B01J 37/0207 (20130101) Acyclic or Carbocyclic Compounds C07C 1/044 (20130101) C07C 2521/04 (20130101) C07C 2521/10 (20130101) C07C 2523/10 (20130101) C07C 2523/755 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040685 | Jayne et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mitegen, LLC (Ithaca, New York) |
| ASSIGNEE(S) | Mitegen, LLC (Ithaca, New York) |
| INVENTOR(S) | Richard Jayne (Lansing, New York); David Closs (Freeville, New York); Benjamin A. Apker (Barton, New York); Robert E. Thorne (Ithaca, New York) |
| ABSTRACT | Humidified sample preparation station for serial crystallography according to one embodiment is a humidified enclosure that delivers relative humidities above 95% and preferably above 97% in standard operation, and that can allow microscope observation of samples within. Humidified sample preparation station for serial crystallography can be used for preparation of protein crystal samples for examination using X-rays and for protein structure determination by X-ray crystallography, involving addition of liquid to the sample and removal of liquid from the sample using vacuum or suction. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397383 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 1/025 (20130101) Original (OR) Class B01L 3/508 (20130101) B01L 7/00 (20130101) B01L 2300/18 (20130101) B01L 2300/123 (20130101) B01L 2300/0663 (20130101) Optical Elements, Systems, or Apparatus G02B 21/06 (20130101) G02B 27/0006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040894 | Bevelhimer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark S. Bevelhimer (Oak Ridge, Tennessee); Ryan Saylor (Oak Ridge, Tennessee) |
| ABSTRACT | A fish model to replace the use of live fish in hydroelectric studies is provided. The fish model is cast from ballistic gel to include the density, dimensions, and weight distribution of a selected species of living fish. The fish model is formed by additively manufacturing a mold based on a three-dimensional scan of an actual fish. The mold is then used to mass produce fish models for force measurement testing at various blade speeds, thickness, and impact angles. Each fish model includes a surrogate skin and an internal sensor for strike force measurements. Optional additional sensors include strain gauges, temperature probes, pressure probes, and load sensors, for example. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/391142 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/3842 (20130101) B29C 45/14 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2089/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/40 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/30 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040920 | Kunc et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (OAK RIDGE, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (OAK RIDGE, Tennessee) |
| INVENTOR(S) | Vlastimil Kunc (Concord, Tennessee); Seokpum KIM (Knoxville, Tennessee); John M. LINDAHL (Knoxville, Tennessee); Jordan A. Failla (Signal Mountain, Tennessee); Chad E. Duty (Loudon, Tennessee) |
| ABSTRACT | An apparatus and device for creating a vertical strengthening feature within a 3D printed article of manufacture for improving mechanical performance in the Z-direction. Fill material is deposited in voids vertically crossing multiple layers during the build of 3D printing. The device includes a penetrating extension that fits within the void to create a vertical strengthening feature via heat and/or extruded fill material. The size and/or movement of the heated extension can impact the void side walls to reflow the build material and blend the layers together within the void side walls. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/509585 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/19 (20190201) B29C 48/22 (20190201) B29C 64/106 (20170801) B29C 64/118 (20170801) B29C 64/165 (20170801) B29C 64/209 (20170801) Original (OR) Class B29C 64/232 (20170801) B29C 70/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041437 | VARDON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Colorado School of Mines (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Derek Richard VARDON (Lakewood, Colorado); Wade A. BRAUNECKER (Boulder, Colorado); Justin Carter JOHNSON (Denver, Colorado); Thomas GENNETT (Denver, Colorado); Rachel Elizabeth MOW (Boulder, Colorado); Kurt Michael VAN ALLSBURG (Denver, Colorado); Gabriella LAHTI (Denver, Colorado) |
| ABSTRACT | Described herein are compositions and methods for the storage and release of hydrogen gas using covalent organic frameworks (COFs). Advantageously, the compositions and methods described herein may be used for the facile and rapid release of hydrogen gas at near ambient temperatures. The described COFs allow for photoactivation, where the release of gas is initiated or the rate of release is increased with the COF is exposed to electromagnetic radiation, for example, UV light. |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 17/393961 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/0015 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041464 | HATCHETT et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, (LasVegas, Nevada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David W. HATCHETT (Las Vegas, Nevada); Kenneth R. CZERWINSKI (Seattle, Washington); Katherine LUEBKE (Las Vegas, Nevada); Cassara HIGGINS (Las Vegas, Nevada) |
| ABSTRACT | Described are methods for the recovery of uranium from uranium hexafluoride dissolved directly into ionic liquids. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 17/438112 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 43/063 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/85 (20130101) C01P 2002/88 (20130101) C01P 2004/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041782 | GUAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Zhibin GUAN (Irvine, California); Aaron M. KUSHNER (Solana Beach, California) |
| ABSTRACT | A self-healing polymer material that includes a multiphase copolymer, and a method of making the copolymer, are provided. The multiphase copolymer includes one or more hydrogen bond-forming copolymer segments, each segment including a polymerized acrylamide monomer and a polymerized acrylic monomer. The polymerized acrylamide monomer includes functional groups that form hydrogen bonds in the multiphase copolymer, and is present in the one or more copolymer segments in an amount sufficient for self-healing of the multiphase copolymer. |
| FILED | Wednesday, August 11, 2021 |
| APPL NO | 17/399883 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 257/02 (20130101) Original (OR) Class C08F 293/005 (20130101) C08F 2438/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041830 | DONG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tao DONG (Lakewood, Colorado); Philip T. PIENKOS (Potsdam, New York) |
| ABSTRACT | The present disclosure relates to a method for making a non-isocyanate polyurethane (NIPU) foam, where the method includes decomposing a blowing agent having at least one of an amine carbamate salt and/or an amine bicarbonate salt to form a diamine and CO2 in the presence of a molecule comprising a plurality of cyclic carbonate functional groups and reacting the diamine with at least a portion of the cyclic carbonate functional groups to form the NIPU foam. In some embodiments of the present disclosure, the reacting and the decomposing may occur at substantially the same rate. |
| FILED | Tuesday, August 10, 2021 |
| APPL NO | 17/398760 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 71/04 (20130101) C08G 2110/005 (20210101) C08G 2110/0058 (20210101) C08G 2110/0066 (20210101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/08 (20130101) Original (OR) Class C08J 2203/02 (20130101) C08J 2375/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041913 | Muhich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Christopher Muhich (Phoenix, Arizona); Jayni Hashimoto (Tempe, Arizona); Daniel Rivera (Mesa, Arizona); Harsheen Rajput (Miami, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Christopher Muhich (Phoenix, Arizona); Jayni Hashimoto (Tempe, Arizona); Daniel Rivera (Mesa, Arizona); Harsheen Rajput (Miami, Arizona) |
| ABSTRACT | High-temperature thermochemical energy storage materials using doped magnesium-transition metal spinel oxides are provided. —transition metal spinel oxides, such as magnesium manganese oxide (MgMn)3O4, are promising candidates for high-temperature thermochemical energy storage applications. However, the use of these materials has been constrained by the limited extent of their endothermic reaction. Embodiments described herein provide for doping magnesium-transition metal spinel oxides to produce a material of low material costs and with high energy densities, creating an avenue for plausibly sized modules with high energy storing capacities. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397495 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 45/1235 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/32 (20130101) C01P 2002/54 (20130101) C01P 2002/72 (20130101) C01P 2006/32 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 5/16 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042031 | Sayre et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NMC, INC. (Los Alamos, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Thomas Sayre (Los Alamos, New Mexico); Somya S. Subramanian (Los Alamos, New Mexico); Natalia Friedland (Palo Alto, California) |
| ABSTRACT | Provided are heterologous nucleic acid constructs, vectors and methods for elevating cyclic electron transfer activity, improving carbon concentration, and enhancing carbon fixation in C3 and C4 plants, and algae, and producing biomass or other products from C3 or C4 plants, and algae, selected from among, for example, starches, oils, fatty acids, lipids, cellulose or other carbohydrates, alcohols, sugars, nutraceuticals, pharmaceuticals, fragrance and flavoring compounds, and organic acids, as well as transgenic plants produced thereby. These methods and transgenic plants and algae encompass the expression, or overexpression, of various combinations of genes that improve carbon concentrating systems in plants and algae, such as bicarbonate transport proteins, carbonic anhydrase, light driven proton pump, cyclic electron flow regulators, etc. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/317362 |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 15/8261 (20130101) C12N 15/8269 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 1/00 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042172 | MILLER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John S. MILLER (Walnut Creek, California); Selim ELHADJ (Livermore, California); Thomas M. SPINKA (Livermore, California) |
| ABSTRACT | A method is disclosed for doping a quantity of powder particles. A container having a central chamber is initially charged with a quantity of powder particles. A quantity of precursor is sublimed to form a heated precursor. A quantity of carrier gas is mixed with the precursor to form a mixture of heated precursor/carrier gas. The central chamber is charged with the heated precursor/carrier gas and then moved to cause interaction of the powder particles with the heated precursor/carrier gas to form a first monolayer coating on the powder particles. The heated precursor/carrier gas is then removed from the central chamber and the central chamber is charged with a O2/O3 gas under a plasma. The central chamber is then further moved to produce interaction of the O2/O3 gas with the first monolayer coating on the powder particles to modify the first monolayer coating to create a different, single monolayer coating forming an oxide coating on the powder particles. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988217 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/45536 (20130101) C23C 16/45544 (20130101) C23C 16/45553 (20130101) C23C 16/45555 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042176 | Jang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gyoung Gug Jang (Oak Ridge, Tennessee); Donovan N. Leonard (Oak Ridge, Tennessee); Ji Heon Jun (Oak Ridge, Tennessee); Michael P. Brady (Oak Ridge, Tennessee); Michael Z. Hu (Oak Ridge, Tennessee); Peter Yancey (Oak Ridge, Tennessee) |
| ABSTRACT | An improved method for preventing corrosion of magnesium is provided. The method includes providing a magnesium substrate including a native surface layer of nanoporous MgO and Mg(OH)2. The method includes generating a CO2 plasma at atmospheric pressure, flowing the CO2 plasma from a nozzle exit as a plasma plume, and exposing the surface film to the plasma plume. The method further includes reacting activated CO2 gas molecules with the native surface layer by performing an atmospheric CO2 plasma treatment at room temperature to convert at least a portion of the native surface layer of nanoporous MgO and Mg(OH)2 into a nano-structured to micro-structured MgO/MgCO3 coating. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/395606 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 22/68 (20130101) C23C 22/82 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042189 | Tripathy |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance,LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Prabhat K. Tripathy (Idaho Falls, Idaho) |
| ABSTRACT | Disclosed are anodes for an electrochemical reduction system, such as for the electrochemical reduction of oxides in systems using molten salt electrolytes. The anodes comprise a rod or plate formed of and include at least one alloy of at least one transition metal and at least one platinum group metal. The alloy anodes may be less expensive than anodes formed solely from platinum group metals and may exhibit less material attrition than anodes formed solely from transition metals. Related methods and electrochemical reduction systems are also disclosed. |
| FILED | Thursday, August 05, 2021 |
| APPL NO | 17/444482 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/17 (20210101) C25B 11/02 (20130101) C25B 11/053 (20210101) C25B 11/091 (20210101) Original (OR) Class Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042191 | HARRISON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin William HARRISON (Erie, Colorado); Nancy Sue FARMER (Arvada, Colorado) |
| ABSTRACT | Disclosed herein are methods, devices and systems to control hydrogen flow and ratios by using electrolyzer stack current to control to gas flowrate and ratio control through using only an electrolyzer stack current to control the H2 mass flow rate to downstream processes requiring precise ratio control of the H2 input gas with other process inputs, like CO2, for example. In an embodiment, the systems disclosed herein deliver a precise ratio control to maintain a stable reaction and minimize excess H2 and CO2 in the product |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397665 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/04 (20130101) C12M 41/34 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 9/19 (20210101) C25B 15/029 (20210101) Original (OR) Class C25B 15/081 (20210101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042366 | Aaron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam M. Aaron (Knoxville, Tennessee); Mahabir S. Bhandari (Knoxville, Tennessee); Venugopal K. Varma (Knoxville, Tennessee); Charles D. Ottinger (Knoxville, Tennessee) |
| ABSTRACT | A gasket assembly for attaching a window to a panel opening includes an inner frame, an outer frame, and an elastic material connecting the inner frame to the outer frame. The elastic material extends contiguously and circumferentially to couple the outer frame to the inner frame. The outer frame and inner frame can include gap flanges and the elastic material can include opposing lateral side portions. The gap flanges are embedded in the lateral side portions of the elastic material. The outer frame includes connecting structure for coupling of the outer frame to the panel opening. The inner frame includes connecting structure for coupling of the gasket assembly to the window. The gasket assembly is configured to support the window in the panel opening and form a seal between the panel opening and the window. A method of making a gasket assembly is also disclosed. |
| FILED | Tuesday, August 03, 2021 |
| APPL NO | 17/393106 |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 1/6069 (20130101) Original (OR) Class E06B 7/2314 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042494 | Kumar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vipin Kumar (Oak Ridge, Tennessee); Vlastimil Kunc (Oak Ridge, Tennessee); Merlin Theodore (Oak Ridge, Tennessee) |
| ABSTRACT | A method of manufacturing a wind turbine blade with integrated lightning strike protection is provided. The method includes forming a plurality of fiber reinforced plies having carbonized textile-grade PAN fibers. The fiber reinforced plies are then stacked on a surface of a mold, wetted with a resin, and cured to form at least part of a wind turbine blade. Because the textile-grade PAN fibers are electrically conductive, the resultant structure provides both electrical conductivity and structural integrity. Laboratory testing of carbon fiber structures against simulated lightning strikes demonstrated high resilience due to their high electrical conductivity both in-plane and in through-thickness directions, with no significant damages, e.g., fiber breakage, resin evaporation, or delamination. High-temperature epoxy helped to improve the performance of the CFRP against the lightning strikes. |
| FILED | Tuesday, August 10, 2021 |
| APPL NO | 17/398063 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/30 (20130101) B29C 70/205 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) Wind Motors F03D 80/30 (20160501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042506 | Wikswo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Ronald S. Reiserer (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); Dmitry A. Markov (Nashville, Tennessee); Clayton M. Britt (Franklin, Kentucky) |
| ABSTRACT | A push-pull micropump includes one or more pairs of channels configured to transfer one or more fluids, each channel pair having an aspiration channel and an injection channel; and an actuator configured to engage the one or more pairs of channels, wherein the actuator comprises a plurality of rolling members and a driving member configured such that when the driving member rotates, the plurality of rolling members rolls along the one or more pairs of channels to cause individually the one or more fluids to transfer through each channel pair simultaneously at different flowrates or the same flowrate, depending upon actuated lengths of the aspiration and injection channels of each channel pair, wherein an actuated length of a channel is defined by a length of the channel along which the plurality of rolling members rolls during a full rotation of the driving member. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/505940 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/12 (20130101) F04B 43/0054 (20130101) F04B 43/0072 (20130101) F04B 43/1253 (20130101) F04B 43/1269 (20130101) Original (OR) Class F04B 43/1292 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042540 | Cole et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert N. Cole (Knoxville, Tennessee); Kevin P. Shay (Knoxville, Tennessee); Austin L. Renfro (Knoxville, Tennessee) |
| ABSTRACT | A foreign material exclusion plug is disclosed. The foreign material plug includes a cylindrical body, a slot, and a breakaway tab. The cylindrical body includes an externally-threaded cylindrical structure. The slot is formed in the cylindrical body extending into the cylindrical body from a top surface of the cylindrical body. The breakaway tab is connected to the cylindrical body and extends outwards from the top surface. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/988846 |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 31/021 (20130101) F16B 37/125 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042718 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (UTRF) (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (UTRF) (Knoxville, Tennessee) |
| INVENTOR(S) | Xiaobing Liu (Oak Ridge, Tennessee); Ming Qu (West Lafayette, Indiana); Joseph K. Warner (San Jose, California); Liang Shi (West Lafayette, Indiana) |
| ABSTRACT | Methods and apparatus are disclosed for high-efficiency thermal storage with a fluid-filled “battery” tank positioned within a fluid-filled “reservoir” tank. Fluid loops couple the tanks to a heat pump and a building. The heat pump can charge the battery tank or deliver thermal energy (cold or heat) to a building, using the reservoir tank or ambient air as a thermal energy source. The battery tank can discharge energy to the building jointly with the heat pump or, at periods of peak electricity usage, with the heat pump switched off. Operating modes allow significant savings in electricity usage and mitigate the “duck curve.” Low duty cycle usage of the reservoir enables efficient underground thermal storage with less digging than conventional geothermal technologies. Additional efficiency is achieved with phase change materials installed inside a tank or in a tank wall, providing temperature regulation. Control methods are disclosed. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 17/434264 |
| CURRENT CPC | Fluid Heaters, e.g Water or Air Heaters, Having Heat Generating Means, in General F24H 4/04 (20130101) Original (OR) Class Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 30/02 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/021 (20130101) F28D 20/0034 (20130101) F28D 2020/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042721 | Podgorney |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert K. Podgorney (Idaho Falls, Idaho) |
| ABSTRACT | A system for power generation from renewable energy, comprising a heat exchanger within a subterranean formation. The heat exchanger comprises a casing at an upper portion of the wellbore, a tubular member extending through the casing to a lower portion of the wellbore, and fins in fluid communication with the casing and with the tubular member, the fins each comprising a volume defined by surfaces of the subterranean formation and configured to receive a fluid from the casing. Related longitudinal finned heat exchangers and methods of storing thermal energy within a subterranean formation are also disclosed. |
| FILED | Tuesday, August 03, 2021 |
| APPL NO | 17/444302 |
| CURRENT CPC | Geothermal Collectors; Geothermal Systems F24T 10/17 (20180501) Original (OR) Class Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 7/12 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/16 (20130101) F28F 2215/06 (20130101) F28F 2250/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044830 | Yacout et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abdellatif M. Yacout (Naperville, Illinois); Sumit Bhattacharya (Darien, Illinois) |
| ABSTRACT | Fuel pellets can include a fission material powder, a protective layer coated on the fission material powder, and an oxidation diffusion barrier coated on the protective layer, with the protective layer and oxidation diffusion barrier being formed through ALD to achieve infiltration of the coatings within the fuel pellets. |
| FILED | Wednesday, August 05, 2020 |
| APPL NO | 16/986180 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/34 (20130101) C23C 16/45525 (20130101) C23C 28/34 (20130101) C23C 28/042 (20130101) Nuclear Reactors G21C 3/047 (20190101) G21C 3/626 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044904 | Lagally et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); The Regents of the University of New Mexico (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Max G. Lagally (Madison, Wisconsin); Matthew McLean Dwyer (Madison, Wisconsin); Francesca Cavallo (Albuquerque, New Mexico); Daniel Warren van der Weide (Madison, Washington); Abhishek Bhat (Madison, Wisconsin) |
| ABSTRACT | Traveling-wave tube amplifiers for high-frequency signals, including terahertz signals, and methods for making a slow-wave structure for the traveling-wave tube amplifiers are provided. The slow-wave structures include helical conductors that are self-assembled via the release and relaxation of strained films from a sacrificial growth substrate. |
| FILED | Thursday, October 21, 2021 |
| APPL NO | 17/507034 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 9/14 (20130101) H01J 23/24 (20130101) H01J 23/26 (20130101) Original (OR) Class H01J 25/34 (20130101) H01J 25/44 (20130101) H01J 2209/012 (20130101) Amplifiers H03F 3/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045232 | Sampayan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Opcondys, Inc. (Manteca, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen E. Sampayan (Manteca, California); Kristin C. Sampayan (Manteca, California) |
| ABSTRACT | Devices, methods and techniques are disclosed to interrupt a fault current in a high-voltage direct-current circuit. In one example aspect, a device includes a mechanical switch including a pair of contacts configured to be positioned apart upon activation of the circuit breaker, and a photoconductive component connected in parallel with the mechanical switch. The photoconductive component is configured to establish a current upon activation of the circuit breaker. The photoconductive component comprises a crystalline material positioned to receive a pulsed light signal from a laser light source, and a pair of electrodes coupled to the crystalline material and configured to allow an electric field to be established across the crystalline material to generate the current. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397699 |
| CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 89/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/161 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045328 | Visco et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California); Vitaliy Nimon (San Francisco, California) |
| ABSTRACT | Batteries, component structures and manufacturing methods, in particular including a glassy embedded battery electrode assembly having a composite material structure composed of interpenetrating material components including a porous electroactive network including a solid electroactive material, and a continuous glassy medium including a Li ion conducting sulfide glass, can achieve enhanced power output, reduced charging time and/or improved cycle life. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/303707 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) Original (OR) Class H01M 4/0471 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045331 | Deng et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Da Deng (Troy, Michigan); Minjun Bae (Detroit, Michigan) |
| ABSTRACT | A device may include a metallic substrate and a plurality of nanorod arrays arranged on the substrate. The nanorod arrays may be made of porous metallic nanostructures and may appear black in color. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/396031 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/70 (20130101) H01M 4/628 (20130101) Original (OR) Class H01M 4/661 (20130101) H01M 4/667 (20130101) H01M 10/052 (20130101) H01M 2004/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045332 | Bao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| INVENTOR(S) | Zhenan Bao (Stanford, California); Zhiao Yu (Stanford, California); Dawei Feng (Stanford, California); Min Ah Lee (Stanford, California); Yi Cui (Stanford, California); Allen Pei (Stanford, California) |
| ABSTRACT | An anode includes: (1) a current collector; and (2) an interfacial layer disposed over the current collector. The interfacial layer includes an ion-conductive organic network including anionic coordination units, organic linkers bonded through the anionic coordination units, and counterions dispersed in the ion-conductive organic network. |
| FILED | Wednesday, October 02, 2019 |
| APPL NO | 17/280649 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/667 (20130101) Original (OR) Class H01M 10/0565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045337 | Zeng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaoqiao Zeng (Naperville, Illinois); Khalil Amine (Oakbrook, Illinois); Jun Lu (Naperville, Illinois); Yuanyuan Guo (Westmont, Illinois) |
| ABSTRACT | A metal-air battery includes an anode; a low-dimensional catalyst cathode; and an electrolyte; wherein: the low-dimensional catalyst cathode comprises a functional metal layer on a carbon support overcoated with a catalyst layer; the electrolyte comprises an aprotic solvent that is an ether-based solvent, a fluorinated ether-based solvent, an oligo (ethylene oxide) solvent, or a mixture of any two or more thereof; and the electrolyte is free of carbonate solvents. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988279 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/926 (20130101) Original (OR) Class H01M 4/8871 (20130101) H01M 12/02 (20130101) H01M 12/08 (20130101) H01M 2004/8689 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045344 | Junker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sven Tobias Junker (Berlin, Connecticut); Tianli Zhu (Glastonbury, Connecticut); Sean C. Emerson (Broad Brook, Connecticut) |
| ABSTRACT | A proton-conducting solid oxide fuel cell system includes a proton-conducting solid oxide fuel cell including an anode through which a flow of fuel is directed, and a cathode through which a flow of air containing 9% to 100% oxygen is directed, and a water recovery portion. The water recovery portion includes an anode water recovery unit to recover anode water from anode products output from the anode, and a cathode water recovery unit to recover cathode water from cathode products output from the cathode. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988044 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/0618 (20130101) Original (OR) Class H01M 8/0675 (20130101) H01M 8/04164 (20130101) H01M 8/04708 (20130101) H01M 8/04843 (20130101) H01M 2008/1293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045349 | XU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kang XU (Potomac, Maryland); Arthur VON WALD CRESCE (Beltsville, Maryland); Oleg A. BORODIN (Laurel, Maryland); Chunsheng WANG (Silver Spring, Maryland); Liumin SUO (Greenbelt, Maryland) |
| ABSTRACT | The present invention is directed to aqueous and hybrid aqueous electrolytes that comprise a lithium salt. The present invention is also directed to methods of making the electrolytes and methods of using the electrolytes in batteries and other electrochemical technologies. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346673 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/5815 (20130101) H01M 10/26 (20130101) H01M 10/36 (20130101) H01M 10/056 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0002 (20130101) H01M 2300/0014 (20130101) H01M 2300/0025 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045352 | Visco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Vitaliy Nimon (San Francisco, California); Valentina Loginova (Walnut Creek, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California) |
| ABSTRACT | Battery component structures and manufacturing methods for solid-state battery cells include a unitary Li ion conducting sulfide glass solid electrolyte structure that serves as the basic building block around which a solid-state battery cell can be fabricated. The unitary glass structure approach can leverage precision controlled high throughput processes from the semiconductor industry that have been inventively modified as disclosed herein for processing a sulfide glass solid electrolyte substrate into a unitary Li ion conducting glass structure, for example, by using etching and lithographic photoresist formulations and methods. The glass substrate may be precision engineered to effectuate a dense glass portion and a porous glass portion that can be characterized as sublayers having predetermined thicknesses. The porous glass sublayer includes a plurality of discrete substantially vertical closed-end holes or trenches that are precision engineered into one or both major substrate surfaces using microfabrication processes. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/303706 |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 15/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045353 | Visco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Vitaliy Nimon (San Francisco, California); Alexei Petrov (Walnut Creek, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California) |
| ABSTRACT | Chemically treating ionically conductive sulfide glass solid electrolyte separators or separator layers can improve performance. In particular, treatment involving chemically etching a surface or surface region of the sulfide glass separator to blunt, lessen or remove edge defects or surface flaws, and/or to enhance surface smoothness is cost effective, reliable and well suited for high production environments compared to physical methods of removing scratches or smoothing surfaces, such as mechanical grinding and polishing. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/303708 |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 3/321 (20130101) C03C 4/14 (20130101) C03C 15/02 (20130101) C03C 2204/00 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045359 | Nanda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jagjit Nanda (Knoxville, Tennessee); Guang Yang (Ferragut, Tennessee); Tomonori Saito (Knoxville, Tennessee); Frank M. Delnick (Maryville, Tennessee) |
| ABSTRACT | A solid electrolyte (SE) composition comprising: (i) a crosslinked organic polymer containing at least one of oxygen and nitrogen atoms; (ii) an inorganic component having a metal oxide or metal sulfide composition and which is distributed throughout the crosslinked organic polymer and interacts by hydrogen bonding with the crosslinked organic polymer; and (iii) metal ions selected from the group consisting of lithium, sodium, potassium, magnesium, calcium, zinc, and aluminum. Also described herein are solid-state batteries comprising: a) an anode; (b) a cathode; and (c) the solid electrolyte composition described above. Also described herein is a method for producing the SE composition, comprising: a) homogeneously mixing the following components: (i) an organic polymer; (ii) an inorganic component; (iii) metal ions, and (iv-b) a low-boiling solvent functioning to dissolve components (i) and (iii); (b) crosslinking the organic polymer to produce a crosslinked organic polymer; and (c) removing the low-boiling solvent. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397233 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 2300/0082 (20130101) H01M 2300/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045366 | HUANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SOLID POWER, INC. (LOUISVILLE, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | HAITAO HUANG (BROOMFIELD, Colorado); BRANDON KELLY (LONGMONT, Colorado); JOSHUA BUETTNER-GARRETT (ARVADA, Colorado) |
| ABSTRACT | A method for producing a solid electrolyte-based electrochemical cell by dry laminating the solid electrolyte layers to active material layers to form composite components, contacting composite components, and packaging the contacted composite components to form a solid electrolyte-based electrochemical cell. |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 17/393978 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/043 (20130101) H01M 4/134 (20130101) H01M 4/382 (20130101) H01M 4/0407 (20130101) H01M 4/661 (20130101) H01M 4/1395 (20130101) H01M 10/052 (20130101) H01M 10/0562 (20130101) H01M 10/0585 (20130101) Original (OR) Class H01M 50/446 (20210101) H01M 50/449 (20210101) H01M 2004/027 (20130101) H01M 2300/0068 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045374 | Pan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Lei Pan (Chicago, Illinois); Tinuade Ololade Folayan (Chicago, Illinois); Jeffrey S. Spangenberger (Naperville, Illinois); Bryant J. Polzin (Deerfield, Illinois) |
| ABSTRACT | Method of separating individual cathode active materials from a mixture of cathode active materials by froth flotation has been developed. They are based on using appropriate chemical reagents that selectively hydrophobize individual cathode active materials to be recovered, so that they can be collected by air bubbles used in flotation and separated from other mixtures. The chemical reagents are amphiphilic molecules with specialized head groups have a strong affinity to metal elements on surfaces of cathode materials. This method enables a separation of individual cathode active material from a mixture of cathode active materials. |
| FILED | Tuesday, August 04, 2020 |
| APPL NO | 16/985028 |
| CURRENT CPC | Flotation; Differential Sedimentation B03D 1/023 (20130101) Non-metallic Elements; Compounds Thereof; C01B 25/45 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/42 (20130101) C01G 53/44 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045506 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Ohio State Innovation Foundation (Columbus, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jin Wang (Powell, Ohio); Risha Na (Columbus, Ohio); Yue Zhang (Upper Arlington, Ohio) |
| ABSTRACT | A T-breaker is an all-in-one solution for dc microgrid fault protection, power flow control, and power quality improvement. A T-breaker features a modular multilevel “T” structure with integrated energy storage devices. The two horizontal arms of the T-breaker realize fault current breaking, load voltage compensation, and power flow control; and the vertical arm of the T-breaker realizes shunt compensation. The configuration provides excellent voltage scalability and relaxes the requirements on the switching signal synchronization during fault transients. The local energy storage in sub-modules eases the fault energy dissipation requirement placed on the traditionally-adopted surge arrestors. The modular multilevel structure also offers immense control flexibility for all types of targeted functions of the provided T-breaker. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/342838 |
| CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 33/596 (20130101) Emergency Protective Circuit Arrangements H02H 7/268 (20130101) Original (OR) Class Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/344 (20210501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045628 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey); UC Berkeley (Berkeley, California) |
| ASSIGNEE(S) | The Trustees of Princeton University (Princeton, New Jersey); UC Berkeley (Berkeley, California) |
| INVENTOR(S) | Minjie Chen (Princeton, New Jersey); Robert Pilawa-Podgurski (Berkeley, California) |
| ABSTRACT | According to various embodiments, a power conversion circuit is disclosed. The power conversion circuit includes at least one DC bus. The power conversion circuit further includes a plurality of DC-AC conversion units coupled to the DC bus and configured to convert a DC voltage into an AC voltage. The power conversion circuit also includes a multi-winding transformer comprising a magnetic core and a plurality of windings, where each DC-AC conversion unit is coupled to a corresponding winding of the multi-winding transformer. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 17/432793 |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/088 (20130101) H02M 7/5387 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20220039708 | Arias et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ana Claudia Arias (Lafayette, California); Donggeon Han (Berkeley, California); Yasser T. Khan (Berkeley, California); Jonathan KangYu Ting (Berkeley, California); Igor Igal Deckman (Albany, California) |
| ABSTRACT | Systems and methods to measure pulse and blood oxygen saturation in tissue using pulse oximetry with an ambient light source. Certain pulse oximeters according to various embodiments advantageously do not require and do not include a light source such as an LED, thereby reducing complexity and reducing power consumption. |
| FILED | Monday, July 12, 2021 |
| APPL NO | 17/373345 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/02427 (20130101) A61B 5/14552 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/305 (20130101) H01L 51/0097 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040349 | Whitten et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David G. Whitten (Albuquerque, New Mexico); Kirk S. Schanze (Gainesville, Florida); Linnea K. Ista (Albuquerque, New Mexico); Patrick L. Donabedian (Gainesville, Florida); Eva Yung Hua Chi (Albuquerque, New Mexico); Florencia A. Monge (Albuquerque, New Mexico); Alison Meredith Kell (Albuquerque, New Mexico) |
| ABSTRACT | A method of inactivating an enveloped ssRNA virus, such as SARS-CoV-2. The method involves contacting the enveloped ssRNA virus with an antiviral polyelectrolyte compound and/or a conjugated aromatic compound effective to inactivate the virus. The disclosure also provides a method of reducing the period of viability of enveloped ssRNA virus, such as SARS-CoV-2, on personal protective equipment, in air, in water, and/or on surfaces that have come into contact with the virus. |
| FILED | Tuesday, October 26, 2021 |
| APPL NO | 17/452296 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 2/10 (20130101) A61L 2/18 (20130101) Original (OR) Class A61L 2/084 (20130101) A61L 9/14 (20130101) A61L 9/20 (20130101) A61L 2101/44 (20200801) A61L 2202/15 (20130101) A61L 2202/24 (20130101) A61L 2202/25 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040698 | BUTLER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason E. BUTLER (Gainesville, Florida); Anthony J. LADD (Gainesville, Florida); Mert ARCA (Hillsboro, Oregon) |
| ABSTRACT | Provided herein are microfluidic devices that can be configured to generate an electrophoretic flow that is in opposition to a fluid flow through a microcapillary of a microfluidic device provided herein. Also provided herein are methods that include adding an amount of particle to the inlet area of a microfluidic device as provided herein, generating a first fluid flow through a microcapillary of a microfluidic device provided herein; and applying a uniform electric field to the microfluidic device, where the uniform electric field generates an electrophoretic flow that is in opposition to the fluid flow. |
| FILED | Thursday, October 21, 2021 |
| APPL NO | 17/506853 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 2200/0668 (20130101) B01L 2400/0421 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6816 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 27/447 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040976 | Iezzi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brian Iezzi (Ann Arbor, Michigan); Max Shtein (Ann Arbor, Michigan); Zahra Afkhami Kheirabadi (Ann Arbor, Michigan); Kira Barton (Ann Arbor, Michigan) |
| ABSTRACT | A method of fabricating a thin film structure includes printing, using an electrohydrodynamic jet (e-jet) printing apparatus, a first layer comprising a first liquid ink, such that the first layer is supported by a substrate, curing the first layer; printing, using the e-jet printing apparatus, a second layer comprising a second liquid ink, such that the second layer is supported by the first layer, and curing the second layer. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/396043 |
| CURRENT CPC | Typewriters; Selective Printing Mechanisms,, i.e Mechanisms Printing Otherwise Than From a Forme; Correction of Typographical Errors B41J 2/06 (20130101) Original (OR) Class B41J 11/00214 (20210101) Photomechanical Production of Textured or Patterned Surfaces, e.g for Printing, for Processing of Semiconductor Devices; Materials Therefor; Originals Therefor; Apparatus Specially Adapted Therefor; G03F 7/2018 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 33/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041659 | SHUSTA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric V. SHUSTA (Madison, Wisconsin); Benjamin UMLAUF (Madison, Wisconsin); Brantley HERRIN (Atlanta, Georgia); Paul CLARK (Madison, Wisconsin); John KUO (Austin, Texas) |
| ABSTRACT | The present disclosure provides isolated polypeptides comprising variable lymphocyte receptors that specifically bind the brain extracellular matrix, compositions, and methods of use. Methods of using the variable lymphocyte receptors for the detection and treatment of disease or injury, specifically, for example, cancers including glioblastoma are provided. |
| FILED | Thursday, December 19, 2019 |
| APPL NO | 17/414581 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041818 | Harth et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Vanderbilt University (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eva M. Harth (Nashville, Tennessee); David M. Stevens (Nashville, Tennessee) |
| ABSTRACT | Disclosed herein are crosslinked polycarbonates, composition thereof and methods thereof. The crosslinked polycarbonates can be prepared from allyl or epoxy polycarbonates. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
| FILED | Wednesday, March 17, 2021 |
| APPL NO | 17/204715 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) A61K 9/19 (20130101) A61K 9/5146 (20130101) A61K 9/5192 (20130101) A61K 47/34 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/06 (20130101) A61L 31/16 (20130101) A61L 31/146 (20130101) A61L 2300/412 (20130101) A61L 2300/416 (20130101) A61L 2400/12 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 59/34 (20130101) C08G 59/66 (20130101) C08G 59/504 (20130101) C08G 64/42 (20130101) C08G 64/0216 (20130101) C08G 64/0241 (20130101) C08G 64/0291 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 3/075 (20130101) C08J 3/246 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/37 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041890 | KUMTA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| INVENTOR(S) | Prashant N. KUMTA (Pittsburgh, Pennsylvania); Sangeetha KUNJUKUNJU (Pittsburgh, Pennsylvania); Nicole J. OSTROWSKI (Pittsburgh, Pennsylvania); Abhijit ROY (Pittsburgh, Pennsylvania); Boeun LEE (Pittsburgh, Pennsylvania); Madhumati RAMANATHAN (Hillsboro, Oregon) |
| ABSTRACT | The invention relates to polyelectrolyte multilayer coatings and, methods for their preparation and application to substrates to enhance the bioactivity and corrosion protection of the substrates' surface. The invention is particularly suitable for coating substrates employed for medical applications, such as but not limited to medical implant devices for drug and/or biologics delivery in a patient. The substrate has a positive or negative charge. The polyelectrolyte multilayer coatings include at least a first polymer layer and a second polymer layer. The first polymer and second polymer have opposite charges. Each of the polymer layers is individually applied using a layer-by-layer such that an alternating charge multilayer coating is formed. |
| FILED | Wednesday, October 06, 2021 |
| APPL NO | 17/495543 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/02 (20130101) A61F 2210/0076 (20130101) A61F 2310/00976 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/04 (20130101) A61L 27/34 (20130101) A61L 27/54 (20130101) A61L 27/58 (20130101) A61L 2300/608 (20130101) A61L 2420/08 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 7/58 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 105/04 (20130101) C09D 167/04 (20130101) C09D 177/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041973 | STINE et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Justin STINE (Hyattsville, Maryland); Luke BEARDSLEE (Cambridge, Massachusetts); Reza GHODSSI (Potomac, Maryland); William E. BENTLEY (Annapolis, Maryland) |
| ABSTRACT | An apparatus for monitoring a bioprocess parameter. The apparatus includes: a housing; a bioprocess sensor attached to an outer surface of the housing; a power supply contained within the housing; and an electronics module contained within the housing and in communication with the power supply and the sensor, where the electronics module includes a wireless communication unit. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 17/286262 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 41/34 (20130101) C12M 41/48 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042031 | Sayre et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NMC, INC. (Los Alamos, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Thomas Sayre (Los Alamos, New Mexico); Somya S. Subramanian (Los Alamos, New Mexico); Natalia Friedland (Palo Alto, California) |
| ABSTRACT | Provided are heterologous nucleic acid constructs, vectors and methods for elevating cyclic electron transfer activity, improving carbon concentration, and enhancing carbon fixation in C3 and C4 plants, and algae, and producing biomass or other products from C3 or C4 plants, and algae, selected from among, for example, starches, oils, fatty acids, lipids, cellulose or other carbohydrates, alcohols, sugars, nutraceuticals, pharmaceuticals, fragrance and flavoring compounds, and organic acids, as well as transgenic plants produced thereby. These methods and transgenic plants and algae encompass the expression, or overexpression, of various combinations of genes that improve carbon concentrating systems in plants and algae, such as bicarbonate transport proteins, carbonic anhydrase, light driven proton pump, cyclic electron flow regulators, etc. |
| FILED | Tuesday, May 11, 2021 |
| APPL NO | 17/317362 |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 15/8261 (20130101) C12N 15/8269 (20130101) Original (OR) Class Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 1/00 (20130101) Technologies for Adaptation to Climate Change Y02A 40/146 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042048 | Saha et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Krishanu Saha (Middleton, Wisconsin); Christian Matthew Capitini (Madison, Wisconsin); Katherine Paige Mueller (Madison, Wisconsin); Nicole Jenine Piscopo (Madison, Wisconsin); Amritava Das (Madison, Wisconsin); Matthew Hull Forsberg (Madison, Wisconsin); Louise Armie Saraspe (Madison, Wisconsin) |
| ABSTRACT | Described herein are non-viral, ex vivo methods of site-specifically inserting a transgene containing a chimeric antigen receptor (CAR) gene into a T cell genome by introducing into a population of unmodified T cells a Cas9 ribonucleoprotein (RNP) and a non-viral double-stranded homology-directed repair (HDR) template, to provide genome-edited T cells. The Cas9 ribonucleoprotein includes a Cas9 protein and a guide RNA that directs double stranded DNA cleavage of a cleavage site in a T cell expressed gene. The non-viral double-stranded HDR template comprises the synthetic DNA sequence flanked by homology arms that are complementary to sequences on both sides of the cleavage site in the T cell expressed gene. The transgene is specifically integrated into the cleavage site of the T cell expressed gene created by the Cas9 RNP in the genome-edited T cells, and the cells are then cultured. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 17/407606 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/22 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2501/599 (20130101) C12N 2800/80 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042187 | Shinde et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (Tuscaloosa, Alabama); THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND D/B/A TULANE UNIVERSITY (New Orleans, Louisiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Pravin Shinde (Tuscaloosa, Alabama); James Donahue (River Ridge, Louisiana); Patricia R. Fontenot (Kenner, Louisiana); Arunava Gupta (Tuscaloosa, Alabama); Shanlin Pan (Tuscaloosa, Alabama) |
| ABSTRACT | Disclosed herein are precursor compounds, composite electrodes comprising the same, and methods of making and use thereof. |
| FILED | Tuesday, October 26, 2021 |
| APPL NO | 17/511020 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 1/55 (20210101) C25B 11/075 (20210101) Original (OR) Class Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/0029 (20130101) H01G 9/2036 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/009 (20130101) H01L 2251/308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042198 | PALMORE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Brown University (Providence, Rhode Island) |
| ASSIGNEE(S) | |
| INVENTOR(S) | G. Tayhas R. PALMORE (Providence, Rhode Island); Taehee KIM (Providence, Rhode Island) |
| ABSTRACT | An electrochemical method includes performing anodic halogenation of Cu foils, performing subsequent oxide-formation in a KHCO3 electrolyte, and performing an electroreduction in neutral KHCO3 to generate a copper catalyst. |
| FILED | Tuesday, August 03, 2021 |
| APPL NO | 17/393151 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 3/26 (20210101) C25B 11/061 (20210101) Processes for the Electrolytic Removal of Materials From Objects; Apparatus Therefor C25F 3/26 (20130101) C25F 7/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042224 | Wong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shing-Chung Josh Wong (Akron, Ohio); Johnny F. Najem (Okaibe, Lebanon); Pei Chen (Beijing, China PRC) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shing-Chung Josh Wong (Akron, Ohio); Johnny F. Najem (Okaibe, Lebanon); Pei Chen (Beijing, China PRC) |
| ABSTRACT | A dry adhesive including a non-woven fabric of nanofibers comprising a polymeric material. The nanofibers include an average diameter within a range of from 50 nm to 10000 nm, and the non-woven fabric of nanofibers has a thickness within a range of from 0.1 μm to 100 μm. The dry adhesive has a shear adhesion strength that is higher than the normal adhesion strength. Additionally disclosed is a dry adhesive fiber mat including substantially aligned fibers extending lengthwise from a first region to a second region, each of the fibers having a diameter that is less than or equal to 10 microns. The dry adhesive fiber mat is selectively repositionable to, from, and between a mechanically interlocked state wherein the fibers at the first region are intimately positioned within void spaces between the fibers at the second region and a separated state not intimately positioned as such. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/509464 |
| CURRENT CPC | Adhesives; Non-mechanical Aspects of Adhesive Processes in General; Adhesive Processes Not Provided for Elsewhere; Use of Materials as Adhesives C09J 5/00 (20130101) C09J 2301/31 (20200801) C09J 2400/263 (20130101) Making Textile Fabrics, e.g From Fibres or Filamentary Material; Fabrics Made by Such Processes or Apparatus, e.g Felts, Non-woven Fabrics; Cotton-wool; Wadding D04H 1/74 (20130101) Original (OR) Class Technical Subjects Covered by Former US Classification Y10T 29/49801 (20150115) Y10T 29/53526 (20150115) Y10T 428/24132 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042295 | Bertoldi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Katia Bertoldi (Cambridge, Massachusetts); Matheus C. Fernandes (Arlington, Massachusetts); James C. Weaver (Cambridge, Massachusetts) |
| ABSTRACT | A structural lattice includes a rectangular base defined by four periphery beams, and two non-diagonal beams that divide the rectangular base in four quadrants. The structural lattice further includes a diagonal reinforcement strut system overlaid on the rectangular base and having at least two intersecting sets of diagonal beams forming an open-and-closed cell architecture. |
| FILED | Wednesday, November 27, 2019 |
| APPL NO | 17/309475 |
| CURRENT CPC | General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/19 (20130101) Original (OR) Class Structural Elements; Building Materials E04C 3/08 (20130101) E04C 5/06 (20130101) E04C 2003/026 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042908 | SCARCELLI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Giuliano SCARCELLI (Washington, District of Columbia); Romanus HUTCHINS (College Park, Maryland); Giulia ZANINI (University Park, Maryland) |
| ABSTRACT | A full-field microscopy method for detection of Brillouin-scattered light includes illuminating a two-dimensional plane in a sample with interrogating light having a first wavelength. Light emitted from the two-dimensional plane can be collected. The emitted light comprises Brillouin-scattered light resulting from interaction of the interrogating light with the sample. The Brillouin-scattered light can have a second wavelength shifted from the first wavelength. The collected light can be passed through a spectrally-selective assembly comprising a gas or vapor illuminated by pumping light. After the spectrally-selective assembly, the Brillouin-scattered light from multiple points in the two-dimensional plane in the sample can be simultaneously detected by an electro-optical sensor. In some embodiments, the spectrally-selective assembly can be altered by changing a wavelength or polarization of the pumping light to allow acquisition of a Brillouin spectrum. |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 17/393532 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/636 (20130101) Original (OR) Class G01N 2021/638 (20130101) Optical Elements, Systems, or Apparatus G02B 21/04 (20130101) G02B 21/361 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042911 | He et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chen He (Chicago, Illinois); David J. Weinberg (San Diego, California); Emily A. Weiss (Evanston, Illinois); Jeremiah Yoonsung Kim (Glenview, Illinois); Chen Wang (Evanston, Illinois); Andrew Lee (Evanston, Illinois) |
| ABSTRACT | The present technology is directed to the nanoparticles for use as molecular environmental sensors. The nanoparticles comprise a photoluminescence core and a plurality of ligands bound to the core and forming a quencher permeable ligand shell. The ligands comprise a reactive or charged moiety capable of being modulated between a first stand and a second state, and the proportion of ligands in each state determine the permeability of the ligand shell to a photoluminescence quencher. |
| FILED | Tuesday, October 19, 2021 |
| APPL NO | 17/505392 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 21/21 (20130101) Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/64 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6428 (20130101) Original (OR) Class G01N 21/6489 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/502 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042917 | LIU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Ming LIU (Riverside, California); Ruoxue YAN (Riverside, California); Xuezhi MA (Riverside, California) |
| ABSTRACT | A method is disclosed for spatial resolution tip-enhanced Raman spectroscopy (TERS) imaging. The method includes physically separating a light excitation region from a Raman signal generation region on a remote-excitation tip-enhanced Raman spectroscopy (RE-TERS) probe. Also disclosed is a method of fabricating a remote-excitation tip-enhanced Raman spectroscopy (TERS) probe, and a system for spatial resolution tip-enhanced Raman spectroscopy (TERS) imaging. The system includes an atomic force microscopy-tip-enhanced Raman spectroscopy (AFM-TERS) system having a RE-TERS probe having a conical tip tapering to a silver nanowire tip (AgNW tip), a silver nanocrystal (AgNC) attached to a side wall of a nanowire, a laser configured to propagate excited surface plasmon polaritons (SPPs) along the nanowire, the nanowire (NW) configured to generate compressed excited surface plasmon polaritons (SPPs), and wherein the conical tip of the nanowire is configured to generate a nano-sized hot spot at a tip apex for TERS excitation. |
| FILED | Friday, November 15, 2019 |
| APPL NO | 17/297930 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/658 (20130101) Original (OR) Class G01N 2201/0633 (20130101) G01N 2201/06113 (20130101) Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 60/38 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042938 | Bhunia et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Swarup Bhunia (Gainesville, Florida); Naren Vikram Raj Masna (Gainesville, Florida); Soumyajit Mandal (Gainesville, Florida); David Joseph Ariando (Gainesville, Florida) |
| ABSTRACT | An exemplary integrated nuclear quadrupole resonance-based detection system comprises a front-end device having a hand-held form factor, wherein the front-end device is configured to scan a sample in or near a sample coil using inbuild electronics and acquire a nuclear quadrupole resonance measurement. The system further includes a swappable sample coil that is attached to an opening at a face of the front-end device and is tuned to a resonant frequency of the sample; and a swappable impedance matching network that is attached to the opening at the face of the front-end device and is configured to tune the resonant frequency of the sample coil. The inbuild electronics comprises a wireless transfer module that is configured to communicate the acquired nuclear quadrupole resonance measurement with a back-end device of the integrated nuclear quadrupole resonance-based detection system. Other systems and methods are also provided. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/389601 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/084 (20130101) G01N 24/087 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/441 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220043024 | Marohn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | John Marohn (Ithaca, New York); Sarah Nathan (Ithaca, New York); Ryan Dwyer (Pewaukee, Wisconsin) |
| ABSTRACT | Atomic force microscopy apparatus and method that enable observing charge generation transients with nanometer spatial resolution and nanosecond to picosecond time resolution, the timescale relevant for studying photo-generated charges in the world's highest efficiency photovoltaic films. The AFM apparatus includes an AFM, a light source for illumination of a sample operatively coupled to the AFM, a voltage source operatively coupled to the AFM, and a control circuitry operatively coupled to the light source and the voltage source. The AFM apparatus improves the time resolution and enables rapid acquisition of photocapacitance transients in a wide array of solar-energy-harvesting materials. |
| FILED | Thursday, October 21, 2021 |
| APPL NO | 17/507104 |
| CURRENT CPC | Scanning-probe Techniques or Apparatus; Applications of Scanning-probe Techniques, e.g Scanning Probe Microscopy [SPM] G01Q 30/00 (20130101) Original (OR) Class G01Q 60/30 (20130101) G01Q 60/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220043473 | Köse et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of South Florida (Tampa, Florida) |
| ASSIGNEE(S) | University of South Florida (Tampa, Florida) |
| INVENTOR(S) | Selçuk Köse (Tampa, Florida); Longfei Wang (Tampa, Florida); S. Karen Khatamifard (Los Angeles, California); Ulya R. Karpuzcu (Minneapolis, Minnesota) |
| ABSTRACT | A DLDO has a configuration that mitigates performance degradation associated with limit cycle oscillation (LCO). The DLDO comprises a clocked comparator, an array of power transistors, a digital controller and a clock pulsewidth reduction circuit. The digital controller comprises control logic configured to generate control signals that cause the power transistors to be turned ON or OFF in accordance with a preselected activation/deactivation control scheme. The clock pulsewidth reduction circuit receives an input clock signal having a first pulsewidth and generates the DLDO clock signal having the preselected pulsewidth that is narrower that the first pulsewidth, which is then delivered to the clock terminals of the clocked comparator and the digital controller. The narrower pulsewidth of the DLDO clock reduces the LCO mode to mitigate performance degradation caused by LCO. |
| FILED | Tuesday, August 24, 2021 |
| APPL NO | 17/410896 |
| CURRENT CPC | Systems for Regulating Electric or Magnetic Variables G05F 1/59 (20130101) Original (OR) Class G05F 1/614 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044626 | Tao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Qiuyang Tao (Atlanta, Georgia); Fumin Zhang (Alpharetta, Georgia); Tony X. Lin (Atlanta, Georgia); Zheyuan Xu (Atlanta, Georgia) |
| ABSTRACT | An exemplary motion capture system, device, and method are disclosed herein to facilitate the implementation of active marker technology onto objects and systems whose design considerations require low weight, low power usage, and/or modular implementation. The exemplary motion capture system, device, and method connect light sources with power driving components through modular, flexible strips and optimized driver circuit configuration and structure for minute unmanned or remote vehicles or wearables having very stringent design constraints. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/389621 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/06 (20130101) B64C 2201/12 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/325 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044809 | Bihorac et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Azra Bihorac (Gainesville, Florida); Tyler J. Loftus (Gainesville, Florida); Tezcan Ozrazgat Baslanti (Gainesville, Florida); Parisa Rashidi (Gainesville, Florida); Benjamin P. Shickel (Alachua, Florida) |
| ABSTRACT | Methods, apparatus, systems, and computer program products for providing patient predictions are provided in various embodiments. Responsive to receiving an indication of initiation of a patient interaction, a model for the patient is initiated by an assessment computing entity. The model has been trained using machine learning and the model is configured to generate a prediction for the patient. The prediction comprises at least one of an acuity score or a mortality prediction. Responsive to identifying a prediction trigger, the assessment computing entity updates the model for the patient based at least in part on medical data corresponding to the patient. The assessment computing entity generates the prediction using the updated deep learning model. The assessment computing entity provides at least a portion of the prediction such that the at least a portion of the prediction may be used to update an electronic health record corresponding to the patient and/or provided to a clinician for review. |
| FILED | Friday, February 21, 2020 |
| APPL NO | 17/309975 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/084 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 10/60 (20180101) G16H 50/20 (20180101) Original (OR) Class G16H 50/30 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045265 | BINEK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christian BINEK (Lincoln, Nebraska); Ather MAHMOOD (Lincoln, Nebraska); William ECHTENKAMP (Lincoln, Nebraska) |
| ABSTRACT | A hall bar device for a memory or logic application can include a gate electrode, a boron-doped chromia layer on the gate electrode; and a hall bar structure with four legs on the boron-doped chromia layer. For a memory application, the hall bar device can be written to by applying a pulse voltage across the gate electrode and one leg of the hall bar structure in the absence of an applied magnetic field; and can be read from by measuring a voltage across the one leg of the hall bar structure and its opposite leg. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988085 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 37/027 (20130101) Static Stores G11C 11/161 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0009 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) Original (OR) Class H01L 43/08 (20130101) H01L 43/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045278 | LUNT, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Richard R. LUNT, III (Williamston, Michigan); John SUDDARD-BANGSUND (Monticello, Minnesota); Christopher TRAVERSE (Haslett, Michigan); Margaret YOUNG (Troy, Michigan) |
| ABSTRACT | Photo-active devices including a substrate, a first electrode, an active layer including an organic salt or salt mixture that selectively or predominantly harvests light from the near infrared or infrared regions of the solar spectrum, and a second electrode. The devices are either visibly transparent or visibly opaque and can be utilized in single- or multi-junction devices. |
| FILED | Monday, August 23, 2021 |
| APPL NO | 17/409009 |
| CURRENT CPC | Organic Dyes or Closely-related Compounds for Producing Dyes; Mordants; Lakes C09B 23/166 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/002 (20130101) H01L 51/006 (20130101) H01L 51/008 (20130101) H01L 51/0046 (20130101) H01L 51/0064 (20130101) Original (OR) Class H01L 51/424 (20130101) H01L 51/4246 (20130101) H01L 2251/308 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045644 | Shtein et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of Michigan (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Max Shtein (Ann Arbor, Michigan); Erin Evke (Ann Arbor, Michigan); Michael Arwashan (Ann Arbor, Michigan); Chao Huang (Ann Arbor, Michigan) |
| ABSTRACT | A device includes a support structure having a plurality of concentric cuts through the support structure that define a set of structure sections. The device also includes an insert assembly supported by the support structure at an inner structure section of the set of structure sections. The inner structure section is configured to tilt the insert assembly at a tilt angle in accordance with a displacement of a first outer structure section of the set of structure sections. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/396110 |
| CURRENT CPC | Solar Heat Collectors; Solar Heat Systems F24S 50/80 (20180501) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 20/32 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045705 | Bendlin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); University of Notre Dame (South Bend, Indiana) |
| ASSIGNEE(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); University of Notre Dame (South Bend, Indiana) |
| INVENTOR(S) | Ralf Bendlin (Cedar Park, Texas); Jonathan David Chisum (South Bend, Indiana); Nicholas Joseph Estes (South Bend, Indiana); Bertrand Martyn Hochwald (South Bend, Indiana) |
| ABSTRACT | Aspects of the subject disclosure may include, for example, receiving, by a first radio module at a first location, a wireless MIMO signal, to obtain a first received RF signal. The wireless MIMO signal includes information originating at a remote MIMO transmitter and conveyed via a wireless channel. An envelope of the first received RF signal is detected by the first radio module without requiring a local oscillator, to obtain a first baseband signal. The first baseband signal may be filtered and/or amplified, after which it is compared to a reference value to obtain a first digital signal that is provided to a digital processor. The digital processor also obtains a second digital signal from a second radio module receiving the wireless MIMO signal at a second location and determines an estimate of the information originating at the remote MIMO transmitter according to the first and second digital signals. Other embodiments are disclosed. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988103 |
| CURRENT CPC | Transmission H04B 1/22 (20130101) Original (OR) Class H04B 7/08 (20130101) H04B 7/0413 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 27/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045967 | Hu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Yih-Chun Hu (Urbana, Illinois); Zhuotao Liu (Santa Clara, California) |
| ABSTRACT | A system and method remotely allocate bandwidth among content consumers on a computing network based on optimizing an aggregate objective pertaining to a plurality of flows of content. The system and method create a profile for each flow of the plurality of flows from a content provider to a content consumer on the computing network. Information is stored in each profile based on at least a metric associated with the corresponding flow. A target bandwidth for each profile is computed remotely, based on optimizing an aggregate objective pertaining to the plurality of flows of content. The optimizing is also based on the information stored in their respective profiles. The system and method distribute the bandwidth to each flow of the plurality of flows based on the target bandwidth remotely computed for each profile. |
| FILED | Wednesday, July 28, 2021 |
| APPL NO | 17/387310 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/781 (20130101) Original (OR) Class H04L 47/805 (20130101) H04L 47/808 (20130101) H04L 47/2408 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220046027 | Klarman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Uri Klarman (Evanston, Illinois); Marcel Flores (Los Angeles, California); Aleksandar Kuzmanovic (Evanston, Illinois) |
| ABSTRACT | A system to generate a web index includes a computing device having a processor and a memory operatively coupled to the memory. The computing device is configured to access a plurality of webpages through a network along a directed route. The computing device is also configured to generate an index corresponding to the plurality of webpages. The computing device is further configured to distribute a digest corresponding to the index to one or more additional computing devices in the network. |
| FILED | Monday, October 07, 2019 |
| APPL NO | 17/281512 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/3239 (20130101) H04L 63/12 (20130101) Original (OR) Class H04L 2209/38 (20130101) H04L 2209/56 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20220039353 | McCreery et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Zeteo Tech, Inc. (Sykesville, Maryland) |
| ASSIGNEE(S) | Zeteo Tech, Inc. (Sykesville, Maryland) |
| INVENTOR(S) | Thomas McCreery (Sykesville, Maryland); Michael McLoughlin (Sykesville, Maryland); Evelyn McCreery (Tucson, Arizona); Noella A. Bryden (Sykesville, Maryland); Stuart Collymore (Sykesville, Maryland); Thomas Sager (Whispering Pines, North Carolina); Rebecca Baxter (Spring Lake, North Carolina) |
| ABSTRACT | Devices and methods for enhanced hearing protection for animals are disclosed. Passive noise reduction components provide reduction of at least 20 dB to 30 dB in dogs using flexible soft muffs that are housed in a hearing protection sleeve. Active noise cancellation (ANC) features may also be used to increase noise reduction to about 40 dB over a large frequency range. The devices may employ passive noise reduction electronic bypass to measure and playback sounds at safe levels bypassing at least one of ANC and passive noise reduction. Communication components may be employed to provide for communication between the handler and the animal. The systems and methods may be used to protect the hearing and utility of military working dogs and hunting dogs. |
| FILED | Sunday, September 15, 2019 |
| APPL NO | 17/275179 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 13/006 (20130101) Original (OR) Class Wireless Communication Networks H04W 4/80 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220039710 | Berthier et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Tasso, Inc. (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Erwin Berthier (Seattle, Washington); Ben Casavant (Seattle, Washington); Ben Moga (Soquel, California) |
| ABSTRACT | The disclosed apparatus, systems and methods relate to the collection of bodily fluids through the use of gravity and microfluidic properties by way of a collector. The collector can make use of microfluidic networks connected to collection sites on the skin of a subject to gather and shuttle blood into a reservoir by a combination of capillary action and gravitational forces. The collected fluid is moved through the microfluidic networks and into the reservoir by a variety of approaches. |
| FILED | Tuesday, May 18, 2021 |
| APPL NO | 17/323567 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/15113 (20130101) A61B 5/15142 (20130101) A61B 5/150022 (20130101) A61B 5/150099 (20130101) A61B 5/150251 (20130101) A61B 5/150343 (20130101) A61B 5/150358 (20130101) Original (OR) Class A61B 5/150412 (20130101) A61B 5/150503 (20130101) A61B 5/150977 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/502715 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040252 | Drake et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles G. Drake (New York, New York); Zoila Areli Lopez-Bujanda (Bethesda, Maryland) |
| ABSTRACT | A method of treating prostate cancer by administration of an IL-8 blocker in combination with androgen ablation. |
| FILED | Friday, August 20, 2021 |
| APPL NO | 17/407537 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/167 (20130101) A61K 31/277 (20130101) A61K 31/4166 (20130101) A61K 31/4439 (20130101) A61K 38/09 (20130101) Original (OR) Class A61K 39/3955 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040255 | Ghadiri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE SCRIPPS RESEARCH INSTITUTE (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Reza M. Ghadiri (San Diego, California); Luke J. Leman (Encinitas, California); Poshen B. Chen (San Diego, California); Yannan Zhao (La Jolla, California); Ali Torkamani (San Diego, California); Audrey Black (San Diego, California) |
| ABSTRACT | The present invention provides methods for remodeling gut microbiome to a desired state. The invention also provides in vitro screening platform for identifying novel agents that can remodel dysfunctional gut microbiome. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 17/280660 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/12 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) C12Q 1/689 (20130101) C12Q 2600/136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040275 | DISIS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Mary L. DISIS (Renton, Washington); Denise Cecil (Shoreline, Washington); Meredith Slota (Seattle, Washington) |
| ABSTRACT | The compositions described herein include an epitope of a peptide that may elicit an immune response in a subject following administration. The compositions may comprise nucleic acids. The compositions may comprise peptides. The methods described herein include administering a composition comprising an epitope of a peptide to a subject in need thereof. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/451607 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/0011 (20130101) Original (OR) Class A61K 39/00115 (20180801) A61K 39/001103 (20180801) A61K 39/001106 (20180801) A61K 39/001129 (20180801) A61K 39/001152 (20180801) A61K 48/00 (20130101) A61K 2039/53 (20130101) A61K 2039/54 (20130101) A61K 2039/572 (20130101) Peptides C07K 14/71 (20130101) C07K 14/705 (20130101) C07K 14/4702 (20130101) C07K 14/70567 (20130101) C07K 14/70596 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/104 (20130101) Enzymes C12Y 203/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040476 | Ray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington University (St. Louis, Missouri); Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wilson Z. Ray (St. Louis, Missouri); Matthew R. MacEwan (St. Louis, Missouri); Zohny S. Zohny (St. Louis, Missouri); John A. Rogers (Evanston, Illinois) |
| ABSTRACT | A system for stimulating tissue generally comprises a resorbable implant. The resorbable implant includes a substrate, at least one contact, and a transceiver, wherein the substrate, the at least one contact, and the transceiver are resorbable. The system also includes a controller configured to communicate with the transceiver of the resorbable implant and a power supply connected to the controller. The controller delivers power to the resorbable implant from the power supply. The resorbable implant delivers electrical stimulation to tissue when the resorbable implant receives power. |
| FILED | Thursday, October 21, 2021 |
| APPL NO | 17/507291 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/20 (20130101) A61N 1/205 (20130101) Original (OR) Class A61N 1/375 (20130101) A61N 1/0456 (20130101) A61N 1/0504 (20130101) A61N 1/37217 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041262 | Slocum et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); LTAG Systems (Bow, New Hampshire) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); LTAG Systems (Bow, New Hampshire) |
| INVENTOR(S) | Alexander H. Slocum (Bow, New Hampshire); Jonathan Slocum (Bow, New Hampshire); George Ni (Cambridge, Massachusetts); Erik Limpaecher (Concord, Massachusetts); Eric Morgan (Bolton, Massachusetts) |
| ABSTRACT | Systems and methods for producing mixed lifting gases (e.g., hydrogen gas and steam) for filling balloons are described. In some embodiments, controlling an altitude of a balloon includes combining a reactant and water to produce hydrogen gas and steam, and flowing the hydrogen gas and steam into the balloon to increase a buoyancy of the balloon. |
| FILED | Wednesday, June 09, 2021 |
| APPL NO | 17/342789 |
| CURRENT CPC | Lighter-than Air Aircraft B64B 1/44 (20130101) Original (OR) Class B64B 1/62 (20130101) B64B 1/64 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041298 | Schurek et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin G. Schurek (West Chester, Pennsylvania); Jacob J. Kowalski (Glen Mills, Pennsylvania); Douglas S. Fischer (Media, Pennsylvania); Barbara A. Meredith (Swarthmore, Pennsylvania); Lenrik E. Toval (Philadelphia, Pennsylvania); Scott J. Brick (Mt. Laurel, New Jersey) |
| ABSTRACT | The present disclosure provides a landing assistance system that, in response to determining that an aircraft is within a deceleration and descent profile, displays a zero speed indicator that indicates a location where the aircraft is calculated to reach zero horizontal speed and zero altitude according to a reference glide path based on flight characteristics of the aircraft. The landing assistance system provides the symbols described herein by determining flight characteristics for an aircraft; calculating where to locate a zero speed indicator based on the flight characteristics; and projecting the zero speed indicator on a display in the aircraft. Low and high speed solutions, as well as azimuth dependent and azimuth independent solutions thereof, quickly and accurately provide the calculations based on the current flight characteristics of the aircraft to thereby provide pilots with landing aids that provide relevant landing information based, in part, on relative locations of the symbols. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/989793 |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 43/00 (20130101) B64D 45/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041305 | Reed, JR. et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Billy B. Reed, JR. (Tucson, Arizona); Mark J. Kocan (Tucson, Arizona) |
| ABSTRACT | A Marman band clamp has multiple parts, such as two halves, that together make up a ring. The halves are joined by diametrically opposed mechanical connections, one of which is a mechanical release separably mechanically coupled ends of the parts (halves). The mechanical release may include an explosive bolt that is used to release the ends of the halves. The mechanical release may capture portions of the release at the ends of the ring halves after severing of the explosive bolt. A nut may be retained by an end of one of the halves by use of a retainer fastener, such as a pin, to prevent the nut from separating from the ring half end when the bolt is severed. This helps retain the pressurized gases between the severed part of the bolt longer, better using the energy from the pressurized gases to reliably separate the ends of the halves. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 16/986351 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 1/641 (20130101) Original (OR) Class Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 2/065 (20130101) F16B 2001/0042 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041666 | van HOEK et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | George Mason University (Fairfax, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Monique L. van HOEK (Centreville, Virginia); Barney M. BISHOP (Annandale, Virginia) |
| ABSTRACT | Peptides are described herein, in particular peptides having antimicrobial properties, as are compositions, articles, and kits comprising such peptides, and methods for using the peptides. |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 17/393495 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 15/32 (20130101) Peptides C07K 7/08 (20130101) C07K 14/463 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56911 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042478 | Bailey et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas Anthony Bailey (Monterey, California); Christopher Michael Girouard (Seaside, California); Anthony Gerard Pollman (Monterey, California) |
| ABSTRACT | The invention relates to a liquid air energy storage system. The storage system includes a cryocooler, a dewar, and a Sterling engine. The cryocooler cools a tip of a cold head to cryogenic temperatures, the cryocooler further includes a heat sink to reject heat from the cryocooler and a cold head that protrudes into a dewar through a cryocooler cavity, the cold head to condense ambient air to create liquified air in the dewar. The dewar holds the liquified air at low temperatures, the dewar having the cryocooler cavity and a Stirling cavity. The Stirling engine drives an electric generator, the Stirling engine further including a cold finger protruding into the dewar through the Stirling cavity, the cold finger to move the liquified air from the dewar to a Stirling heat sink; the Stirling heat sink to expand the liquified air; and the electric generator to generate output electricity. |
| FILED | Tuesday, August 03, 2021 |
| APPL NO | 17/393275 |
| CURRENT CPC | Hot Gas or Combustion-product Positive-displacement Engine Plants; Use of Waste Heat of Combustion Engines; Not Otherwise Provided for F02G 1/055 (20130101) F02G 1/057 (20130101) Original (OR) Class F02G 2243/00 (20130101) Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 7/04 (20130101) F17C 9/04 (20130101) F17C 2221/031 (20130101) F17C 2223/0161 (20130101) F17C 2265/07 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042506 | Wikswo et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Ronald S. Reiserer (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); Dmitry A. Markov (Nashville, Tennessee); Clayton M. Britt (Franklin, Kentucky) |
| ABSTRACT | A push-pull micropump includes one or more pairs of channels configured to transfer one or more fluids, each channel pair having an aspiration channel and an injection channel; and an actuator configured to engage the one or more pairs of channels, wherein the actuator comprises a plurality of rolling members and a driving member configured such that when the driving member rotates, the plurality of rolling members rolls along the one or more pairs of channels to cause individually the one or more fluids to transfer through each channel pair simultaneously at different flowrates or the same flowrate, depending upon actuated lengths of the aspiration and injection channels of each channel pair, wherein an actuated length of a channel is defined by a length of the channel along which the plurality of rolling members rolls during a full rotation of the driving member. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/505940 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/12 (20130101) F04B 43/0054 (20130101) F04B 43/0072 (20130101) F04B 43/1253 (20130101) F04B 43/1269 (20130101) Original (OR) Class F04B 43/1292 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042905 | Salaita et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Khalid Salaita (Atlanta, Georgia); Yixiao Dong (Atlanta, Georgia) |
| ABSTRACT | This disclosure relates to non-naturally occurring light reflecting or color changing materials comprising a segmented array of flexible polymers, wherein the segmented array of flexible polymers comprise photonic crystal lattices embedded therein, wherein the segmented array of flexible polymers are themselves embedded within an elastic supporting polymer that maintains a near constant size during chromatic shifting of the photonic crystal lattices. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397318 |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/22 (20130101) C08K 3/36 (20130101) C08K 7/24 (20130101) C08K 2003/2275 (20130101) C08K 2201/011 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/31 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220043311 | Basu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Rajratan Basu (Columbia, Maryland) |
| ABSTRACT | An electro-optical liquid crystal cell comprising a first substrate, a first layer of indium tin oxide (ITO) on the first substrate, a first layer of WSe2 on the first layer of ITO on the first substrate, and a layer of liquid crystal on the first layer of WSe2 on the first layer of ITO on the first substrate. Furthermore, the electro-optical liquid crystal cell can comprise a second layer of WSe2, a second layer of ITO, and a second substrate. This WSe2 cell exhibits the required electro-optic effect needed for a liquid crystal display. This WSe2 cell exhibits high optical transmission. |
| FILED | Friday, June 04, 2021 |
| APPL NO | 17/338784 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/133711 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220043323 | SKIRLO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Scott A. SKIRLO (Boston, Massachusetts); Cheryl Marie SORACE-AGASKAR (Bedford, Massachusetts); Marin SOLJACIC (Belmont, Massachusetts); Simon VERGHESE (Arlington, Massachusetts); Jeffrey S. HERD (Rowley, Massachusetts); Paul William JUODAWLKIS (Arlington, Massachusetts); Yi YANG (Cambridge, Massachusetts); DIRK ENGLUND (Brookline, Massachusetts); Mihika PRABHU (Cambridge, Massachusetts) |
| ABSTRACT | An integrated optical beam steering device includes a planar dielectric lens that collimates beams from different inputs in different directions within the lens plane. It also includes an output coupler, such as a grating or photonic crystal, that guides the collimated beams in different directions out of the lens plane. A switch matrix controls which input port is illuminated and hence the in-plane propagation direction of the collimated beam. And a tunable light source changes the wavelength to control the angle at which the collimated beam leaves the plane of the substrate. The device is very efficient, in part because the input port (and thus in-plane propagation direction) can be changed by actuating only log2 N of the N switches in the switch matrix. It can also be much simpler, smaller, and cheaper because it needs fewer control lines than a conventional optical phased array with the same resolution. |
| FILED | Friday, October 15, 2021 |
| APPL NO | 17/502151 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 7/4813 (20130101) G01S 7/4814 (20130101) G01S 7/4817 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/311 (20210101) G02F 1/2955 (20130101) G02F 1/3136 (20130101) Original (OR) Class G02F 2201/02 (20130101) G02F 2201/06 (20130101) G02F 2201/302 (20130101) G02F 2203/70 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220043639 | Jennings et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| ASSIGNEE(S) | BAE Systems Information and Electronic Systems Integration Inc. (Nashua, New Hampshire) |
| INVENTOR(S) | Mark R. Jennings (New Milford, New Jersey); Jeffrey L. Neuman (New York, New York) |
| ABSTRACT | The system and method for decoupling algorithms from a Mission Data Tool suite, or the like, into a scalable, modular and multithreaded tool set callable from a variety of environments. The system generates data objects representing inputs, outputs and field validation capable of being accessed from a framework callable from Java or C#, for example. Data objects are defined in an abstract Independent Definition Language (IDL) and the objects are then generated into the target languages for use by a software component's application programming interface (API). The resulting generated code may also contain serialization/deserialization routines needed for object transfer between different systems in a seamless manner. In some cases, transfer of the objects, algorithmic generation of data into the objects, and the transfer of outputs back to the calling system is possible with minimal overhead and interaction on either end. |
| FILED | Friday, June 21, 2019 |
| APPL NO | 17/275843 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/315 (20130101) G06F 8/447 (20130101) Original (OR) Class G06F 9/541 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220043813 | Mirhaji |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Parsa Mirhaji (Pearland, Texas) |
| ABSTRACT | Systems and method to aid in the collection, representation and mining of data are disclosed. More particularly, embodiments as disclosed may utilize a unifying format to represent data obtained or utilized by a system to facilitate linking between data from different sources and the commensurate ability to mine such data. Specifically, embodiments may represent data as graphs that comprise the concepts and relationships between those concepts. In this manner, concepts in graphs that represent distinct groupings of data may be mapped and knowledge mining with respect to these graphs facilitated. |
| FILED | Friday, October 08, 2021 |
| APPL NO | 17/497682 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/22 (20190101) G06F 16/248 (20190101) G06F 16/367 (20190101) G06F 16/2465 (20190101) Original (OR) Class G06F 16/3329 (20190101) G06F 16/3344 (20190101) G06F 16/9024 (20190101) G06F 40/211 (20200101) G06F 40/253 (20200101) G06F 40/284 (20200101) G06F 40/289 (20200101) Computer Systems Based on Specific Computational Models G06N 5/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220043948 | Maxwell, III et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Palo Alto Research Center Incorporated (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John T. Maxwell, III (Santa Clara, California); Matthew Klenk (San Francisco, California); Johan de Kleer (Los Altos, California) |
| ABSTRACT | A computer simulation includes qualitative values and constraints of a qualitative state. At least some of the constraints include additions of at least some of the qualitative values. The qualitative values are converted to inequalities and equalities. A subset of the original constraints is extracted that represents all of the additions. A conflict resolution method is applied to the inequalities along with the addition constraints. The conflict resolution method makes a tentative assignment of numerical values to the quantitative values and determines consistencies over all of the inequalities and equalities using the tentative assignments. Based on the conflict resolution method determining that the addition constraints reduce to a trivial inconsistency, the qualitative state can be invalidated. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 16/986601 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/20 (20200101) Original (OR) Class G06F 2111/04 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044077 | Lawson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aaron Lawson (San Jose, California); Mitchell L. McLaren (Everton Park, Australia); Diego Castan Lavilla (Dobbs Ferry, New York) |
| ABSTRACT | In some examples, a system includes a storage device; and processing circuitry having access to the storage device. The processing circuitry is configured to receive information indicative of a media dataset, where the media dataset corresponds to an object; and analyze the media dataset to compute a corresponding set of operating condition weight values. Additionally, the processing circuitry is configured to compare the set of operating condition weight values corresponding to the media dataset with a plurality of sets of reference operating condition weight values that each correspond to a different reference media dataset of a plurality of reference media datasets; and determine, based on the comparison of the set of operating condition weight values with the plurality of sets of reference operating condition weight values, an indication of a capability of a trained machine learning model to correctly verify the object in the media dataset. |
| FILED | Friday, October 22, 2021 |
| APPL NO | 17/508365 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/627 (20130101) G06K 9/6256 (20130101) G06K 9/6264 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044100 | Yoo |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Sung-Joo Ben Yoo (Davis, California) |
| ABSTRACT | The disclosed embodiments relate to a nanophotonic computing system, which comprises a set of nanophotonic computing elements and an optical interconnect that interconnects the set of nanophotonic computing elements. The optical interconnect includes one or more nanophotonic synaptic interconnect devices (NSIDs), which provide unitary and all-to-all interconnects between NSID inputs and NSID outputs, wherein each NSID comprises free-space propagation regions connected by an array of waveguides to facilitate routing different wavelengths. These waveguides include phase modulators for varying optical lengths of the waveguides, wherein varying the optical lengths of the waveguides facilitates adjusting weights on interconnections through the NSID in a lossless manner. |
| FILED | Friday, July 31, 2020 |
| APPL NO | 16/945285 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/2955 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/063 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044182 | Krikorian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | The Boeing Company (Chicago, Illinois) |
| INVENTOR(S) | Haig Francis Krikorian (Fullerton, California); Leo Ho Chi Hui (Alhambra, California) |
| ABSTRACT | In one example aspect, a computer-implemented method or managing one or more members during an encounter in a competitive environment in a “prudent yet aggressive” fashion includes: receiving input data relating to the encounter within the competitive environment; at incrementing timesteps, executing a simulation to select different move sets during progression of the encounter, each move set defining movements or assignments of each of the one or more members as part of developing a strategy. Selecting different move sets includes: generating first move set options for containing one or more opponents by members based on the input data; selecting a first move set; generating a node identifying the selected first move set option; generating second move set options based on the node as input; selecting a second move set; determining that objectives have been met; and generating and outputting instructions associated with the first and second move sets. |
| FILED | Friday, June 18, 2021 |
| APPL NO | 17/352099 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/06393 (20130101) Original (OR) Class G06Q 10/06398 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044626 | Tao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Georgia Tech Research Corporation (Atlanta, Georgia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Qiuyang Tao (Atlanta, Georgia); Fumin Zhang (Alpharetta, Georgia); Tony X. Lin (Atlanta, Georgia); Zheyuan Xu (Atlanta, Georgia) |
| ABSTRACT | An exemplary motion capture system, device, and method are disclosed herein to facilitate the implementation of active marker technology onto objects and systems whose design considerations require low weight, low power usage, and/or modular implementation. The exemplary motion capture system, device, and method connect light sources with power driving components through modular, flexible strips and optimized driver circuit configuration and structure for minute unmanned or remote vehicles or wearables having very stringent design constraints. |
| FILED | Friday, July 30, 2021 |
| APPL NO | 17/389621 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 39/024 (20130101) B64C 2201/06 (20130101) B64C 2201/12 (20130101) Arrangements or Circuits for Control of Indicating Devices Using Static Means to Present Variable Information G09G 3/325 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044727 | Cambou et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bertrand F. Cambou (Flagstaff, Arizona); Julie B. Heynssens (Flagstaff, Arizona); Ian Burke (Flagstaff, Arizona); Taylor Wilson (Flagstaff, Arizona) |
| ABSTRACT | A system and method of secure communication between computing devices based on physical unclonable functions such as memories having dissolvable conductive paths is provided. The method involves enrolling a client device, the client device having a PUF such as a pristine ReRAM. The PUF is enrolled in a secure environment by reading and storing the resistances of the PUF's addressable memory cells. The cells are categorized into “rugged” and “vulnerable” categories on the basis of their resistance, the vulnerable cells being those more likely to be permanently altered during the generations of PUF responses. The rugged cells are used for the generation of PUF responses for cryptographic key generation, but the vulnerable cells may be inspected to detect unauthorized 3rd party access to the PUF. |
| FILED | Thursday, August 05, 2021 |
| APPL NO | 17/395360 |
| CURRENT CPC | Static Stores G11C 13/004 (20130101) G11C 13/0069 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0819 (20130101) H04L 9/3278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044904 | Lagally et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin); The Regents of the University of New Mexico (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Max G. Lagally (Madison, Wisconsin); Matthew McLean Dwyer (Madison, Wisconsin); Francesca Cavallo (Albuquerque, New Mexico); Daniel Warren van der Weide (Madison, Washington); Abhishek Bhat (Madison, Wisconsin) |
| ABSTRACT | Traveling-wave tube amplifiers for high-frequency signals, including terahertz signals, and methods for making a slow-wave structure for the traveling-wave tube amplifiers are provided. The slow-wave structures include helical conductors that are self-assembled via the release and relaxation of strained films from a sacrificial growth substrate. |
| FILED | Thursday, October 21, 2021 |
| APPL NO | 17/507034 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 9/14 (20130101) H01J 23/24 (20130101) H01J 23/26 (20130101) Original (OR) Class H01J 25/34 (20130101) H01J 25/44 (20130101) H01J 2209/012 (20130101) Amplifiers H03F 3/58 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045265 | BINEK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christian BINEK (Lincoln, Nebraska); Ather MAHMOOD (Lincoln, Nebraska); William ECHTENKAMP (Lincoln, Nebraska) |
| ABSTRACT | A hall bar device for a memory or logic application can include a gate electrode, a boron-doped chromia layer on the gate electrode; and a hall bar structure with four legs on the boron-doped chromia layer. For a memory application, the hall bar device can be written to by applying a pulse voltage across the gate electrode and one leg of the hall bar structure in the absence of an applied magnetic field; and can be read from by measuring a voltage across the one leg of the hall bar structure and its opposite leg. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988085 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 37/027 (20130101) Static Stores G11C 11/161 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 1/0009 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 43/02 (20130101) Original (OR) Class H01L 43/08 (20130101) H01L 43/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045349 | XU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Maryland, College Park (College Park, Maryland); The United States of America as Represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kang XU (Potomac, Maryland); Arthur VON WALD CRESCE (Beltsville, Maryland); Oleg A. BORODIN (Laurel, Maryland); Chunsheng WANG (Silver Spring, Maryland); Liumin SUO (Greenbelt, Maryland) |
| ABSTRACT | The present invention is directed to aqueous and hybrid aqueous electrolytes that comprise a lithium salt. The present invention is also directed to methods of making the electrolytes and methods of using the electrolytes in batteries and other electrochemical technologies. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346673 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/505 (20130101) H01M 4/525 (20130101) H01M 4/5815 (20130101) H01M 10/26 (20130101) H01M 10/36 (20130101) H01M 10/056 (20130101) Original (OR) Class H01M 10/0568 (20130101) H01M 10/0569 (20130101) H01M 2300/0002 (20130101) H01M 2300/0014 (20130101) H01M 2300/0025 (20130101) H01M 2300/0091 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220046169 | Divitt et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Shawn Divitt (Gaithersburg, Maryland); Samuel Park (McLean, Virginia) |
| ABSTRACT | An Incoherent Fourier ptychographic imaging system. Multiple known light patterns are projected sequentially onto a target and images of the combined pattern and target are recorded by a camera, with the images being processed using an optical transfer function (OTF). The camera and projection system are aligned along the same optical axis. The known illumination patterns and the optical transfer function (OTF) are combined in an iterative algorithm to generate an image with resolution greater than would be achieved by uniform illumination of the target and imaging with the camera. |
| FILED | Tuesday, July 27, 2021 |
| APPL NO | 17/386005 |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/265 (20130101) H04N 5/2256 (20130101) H04N 5/23232 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Federally Funded Research and Development Centers (FFRDC)
| US 20220040463 | Frye et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clint D. Frye (Livermore, California); Mihail Bora (Livermore, California); Adam M. Conway (Livermore, California); Devin Joseph Funaro (Livermore, California); Paulius Vytautas Grivickas (Livermore, California); David L. Hall (San Ramon, California); Lars F. Voss (Livermore, California) |
| ABSTRACT | A product includes an elongated carbon-containing pillar having a bottom and a tip opposite the bottom. The width of the pillar measured 1 nm below the tip is less than 700 nm. A method includes masking a carbon-containing single crystal for defining masked regions and unmasked regions on the single crystal. The method also includes performing a plasma etch for removing portions of the unmasked regions of the single crystal, thereby defining a pillar in each unmasked region, and performing a chemical etch on the pillars at a temperature between 1200° C. and 1600° C. for selectively reducing a width of each pillar. |
| FILED | Thursday, August 06, 2020 |
| APPL NO | 16/987121 |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) Original (OR) Class A61M 2037/0023 (20130101) A61M 2037/0053 (20130101) Microstructural Devices or Systems, e.g Micromechanical Devices B81B 1/008 (20130101) B81B 2201/055 (20130101) Processes or Apparatus Specially Adapted for the Manufacture or Treatment of Microstructural Devices or Systems B81C 1/00531 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040596 | RESTIVO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (AIKEN, South Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MICHAEL L. RESTIVO (AIKEN, South Carolina); MICHAEL R. POIRIER (EVANS, Georgia); FERNANDO F. FONDEUR (NORTH AUGUSTA, South Carolina); SAMUEL D. FINK (AIKEN, South Carolina) |
| ABSTRACT | Centrifugal contactors that can be used for mixing or separating materials are described. The contactors include a sensing system including a communications fiber within the shaft of the contactors and access ports providing access from the communications fiber to the mixing/separating zone of the contactor. The sensing system can be utilized during operation of the contactor and can provide for detailed and accurate on-line characterization of a protocol, as well as process control and system modification as necessary during operation. |
| FILED | Wednesday, August 05, 2020 |
| APPL NO | 16/985894 |
| CURRENT CPC | Separation B01D 11/048 (20130101) Original (OR) Class Centrifuges B04B 1/02 (20130101) B04B 11/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220040677 — MULTIMETALLIC CATALYSTS FOR METHANATION OF CARBON DIOXIDE AND DRY REFORMING OF METHANE
| US 20220040677 | Ferrandon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Magali Ferrandon (Steger, Illinois); Gokhan Celik (Clarendon Hills, Illinois); Massimiliano Delferro (Chicago, Illinois) |
| ABSTRACT | Processes for forming multimetallic catalysts by grafting nickel precusors to metal oxide supports. Dry reforming reaction catalysts having nickel and promotors grafted to metal oxides supports. Methanation reaction catalysts having nickel and promotors grafted to metal oxides supports. |
| FILED | Tuesday, August 04, 2020 |
| APPL NO | 16/984836 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/04 (20130101) B01J 21/10 (20130101) B01J 23/10 (20130101) B01J 23/22 (20130101) B01J 23/745 (20130101) B01J 23/755 (20130101) Original (OR) Class B01J 37/18 (20130101) B01J 37/086 (20130101) B01J 37/0203 (20130101) B01J 37/0207 (20130101) Acyclic or Carbocyclic Compounds C07C 1/044 (20130101) C07C 2521/04 (20130101) C07C 2521/10 (20130101) C07C 2523/10 (20130101) C07C 2523/755 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040894 | Bevelhimer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark S. Bevelhimer (Oak Ridge, Tennessee); Ryan Saylor (Oak Ridge, Tennessee) |
| ABSTRACT | A fish model to replace the use of live fish in hydroelectric studies is provided. The fish model is cast from ballistic gel to include the density, dimensions, and weight distribution of a selected species of living fish. The fish model is formed by additively manufacturing a mold based on a three-dimensional scan of an actual fish. The mold is then used to mass produce fish models for force measurement testing at various blade speeds, thickness, and impact angles. Each fish model includes a surrogate skin and an internal sensor for strike force measurements. Optional additional sensors include strain gauges, temperature probes, pressure probes, and load sensors, for example. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/391142 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 33/3842 (20130101) B29C 45/14 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2089/00 (20130101) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/40 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 3/30 (20130101) Measuring Linear or Angular Speed, Acceleration, Deceleration, or Shock; Indicating Presence, Absence, or Direction, of Movement G01P 15/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040920 | Kunc et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (OAK RIDGE, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (OAK RIDGE, Tennessee) |
| INVENTOR(S) | Vlastimil Kunc (Concord, Tennessee); Seokpum KIM (Knoxville, Tennessee); John M. LINDAHL (Knoxville, Tennessee); Jordan A. Failla (Signal Mountain, Tennessee); Chad E. Duty (Loudon, Tennessee) |
| ABSTRACT | An apparatus and device for creating a vertical strengthening feature within a 3D printed article of manufacture for improving mechanical performance in the Z-direction. Fill material is deposited in voids vertically crossing multiple layers during the build of 3D printing. The device includes a penetrating extension that fits within the void to create a vertical strengthening feature via heat and/or extruded fill material. The size and/or movement of the heated extension can impact the void side walls to reflow the build material and blend the layers together within the void side walls. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/509585 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 48/19 (20190201) B29C 48/22 (20190201) B29C 64/106 (20170801) B29C 64/118 (20170801) B29C 64/165 (20170801) B29C 64/209 (20170801) Original (OR) Class B29C 64/232 (20170801) B29C 70/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041437 | VARDON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Colorado School of Mines (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Derek Richard VARDON (Lakewood, Colorado); Wade A. BRAUNECKER (Boulder, Colorado); Justin Carter JOHNSON (Denver, Colorado); Thomas GENNETT (Denver, Colorado); Rachel Elizabeth MOW (Boulder, Colorado); Kurt Michael VAN ALLSBURG (Denver, Colorado); Gabriella LAHTI (Denver, Colorado) |
| ABSTRACT | Described herein are compositions and methods for the storage and release of hydrogen gas using covalent organic frameworks (COFs). Advantageously, the compositions and methods described herein may be used for the facile and rapid release of hydrogen gas at near ambient temperatures. The described COFs allow for photoactivation, where the release of gas is initiated or the rate of release is increased with the COF is exposed to electromagnetic radiation, for example, UV light. |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 17/393961 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/0015 (20130101) Original (OR) Class Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 1/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041830 | DONG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tao DONG (Lakewood, Colorado); Philip T. PIENKOS (Potsdam, New York) |
| ABSTRACT | The present disclosure relates to a method for making a non-isocyanate polyurethane (NIPU) foam, where the method includes decomposing a blowing agent having at least one of an amine carbamate salt and/or an amine bicarbonate salt to form a diamine and CO2 in the presence of a molecule comprising a plurality of cyclic carbonate functional groups and reacting the diamine with at least a portion of the cyclic carbonate functional groups to form the NIPU foam. In some embodiments of the present disclosure, the reacting and the decomposing may occur at substantially the same rate. |
| FILED | Tuesday, August 10, 2021 |
| APPL NO | 17/398760 |
| CURRENT CPC | Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 71/04 (20130101) C08G 2110/005 (20210101) C08G 2110/0058 (20210101) C08G 2110/0066 (20210101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/08 (20130101) Original (OR) Class C08J 2203/02 (20130101) C08J 2375/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042172 | MILLER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John S. MILLER (Walnut Creek, California); Selim ELHADJ (Livermore, California); Thomas M. SPINKA (Livermore, California) |
| ABSTRACT | A method is disclosed for doping a quantity of powder particles. A container having a central chamber is initially charged with a quantity of powder particles. A quantity of precursor is sublimed to form a heated precursor. A quantity of carrier gas is mixed with the precursor to form a mixture of heated precursor/carrier gas. The central chamber is charged with the heated precursor/carrier gas and then moved to cause interaction of the powder particles with the heated precursor/carrier gas to form a first monolayer coating on the powder particles. The heated precursor/carrier gas is then removed from the central chamber and the central chamber is charged with a O2/O3 gas under a plasma. The central chamber is then further moved to produce interaction of the O2/O3 gas with the first monolayer coating on the powder particles to modify the first monolayer coating to create a different, single monolayer coating forming an oxide coating on the powder particles. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988217 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/403 (20130101) C23C 16/45536 (20130101) C23C 16/45544 (20130101) C23C 16/45553 (20130101) C23C 16/45555 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042176 | Jang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gyoung Gug Jang (Oak Ridge, Tennessee); Donovan N. Leonard (Oak Ridge, Tennessee); Ji Heon Jun (Oak Ridge, Tennessee); Michael P. Brady (Oak Ridge, Tennessee); Michael Z. Hu (Oak Ridge, Tennessee); Peter Yancey (Oak Ridge, Tennessee) |
| ABSTRACT | An improved method for preventing corrosion of magnesium is provided. The method includes providing a magnesium substrate including a native surface layer of nanoporous MgO and Mg(OH)2. The method includes generating a CO2 plasma at atmospheric pressure, flowing the CO2 plasma from a nozzle exit as a plasma plume, and exposing the surface film to the plasma plume. The method further includes reacting activated CO2 gas molecules with the native surface layer by performing an atmospheric CO2 plasma treatment at room temperature to convert at least a portion of the native surface layer of nanoporous MgO and Mg(OH)2 into a nano-structured to micro-structured MgO/MgCO3 coating. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/395606 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 22/68 (20130101) C23C 22/82 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042189 | Tripathy |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance,LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Prabhat K. Tripathy (Idaho Falls, Idaho) |
| ABSTRACT | Disclosed are anodes for an electrochemical reduction system, such as for the electrochemical reduction of oxides in systems using molten salt electrolytes. The anodes comprise a rod or plate formed of and include at least one alloy of at least one transition metal and at least one platinum group metal. The alloy anodes may be less expensive than anodes formed solely from platinum group metals and may exhibit less material attrition than anodes formed solely from transition metals. Related methods and electrochemical reduction systems are also disclosed. |
| FILED | Thursday, August 05, 2021 |
| APPL NO | 17/444482 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 9/17 (20210101) C25B 11/02 (20130101) C25B 11/053 (20210101) C25B 11/091 (20210101) Original (OR) Class Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 3/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042191 | HARRISON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kevin William HARRISON (Erie, Colorado); Nancy Sue FARMER (Arvada, Colorado) |
| ABSTRACT | Disclosed herein are methods, devices and systems to control hydrogen flow and ratios by using electrolyzer stack current to control to gas flowrate and ratio control through using only an electrolyzer stack current to control the H2 mass flow rate to downstream processes requiring precise ratio control of the H2 input gas with other process inputs, like CO2, for example. In an embodiment, the systems disclosed herein deliver a precise ratio control to maintain a stable reaction and minimize excess H2 and CO2 in the product |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397665 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 21/04 (20130101) C12M 41/34 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/04 (20130101) C25B 9/19 (20210101) C25B 15/029 (20210101) Original (OR) Class C25B 15/081 (20210101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042366 | Aaron et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam M. Aaron (Knoxville, Tennessee); Mahabir S. Bhandari (Knoxville, Tennessee); Venugopal K. Varma (Knoxville, Tennessee); Charles D. Ottinger (Knoxville, Tennessee) |
| ABSTRACT | A gasket assembly for attaching a window to a panel opening includes an inner frame, an outer frame, and an elastic material connecting the inner frame to the outer frame. The elastic material extends contiguously and circumferentially to couple the outer frame to the inner frame. The outer frame and inner frame can include gap flanges and the elastic material can include opposing lateral side portions. The gap flanges are embedded in the lateral side portions of the elastic material. The outer frame includes connecting structure for coupling of the outer frame to the panel opening. The inner frame includes connecting structure for coupling of the gasket assembly to the window. The gasket assembly is configured to support the window in the panel opening and form a seal between the panel opening and the window. A method of making a gasket assembly is also disclosed. |
| FILED | Tuesday, August 03, 2021 |
| APPL NO | 17/393106 |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 1/6069 (20130101) Original (OR) Class E06B 7/2314 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042494 | Kumar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vipin Kumar (Oak Ridge, Tennessee); Vlastimil Kunc (Oak Ridge, Tennessee); Merlin Theodore (Oak Ridge, Tennessee) |
| ABSTRACT | A method of manufacturing a wind turbine blade with integrated lightning strike protection is provided. The method includes forming a plurality of fiber reinforced plies having carbonized textile-grade PAN fibers. The fiber reinforced plies are then stacked on a surface of a mold, wetted with a resin, and cured to form at least part of a wind turbine blade. Because the textile-grade PAN fibers are electrically conductive, the resultant structure provides both electrical conductivity and structural integrity. Laboratory testing of carbon fiber structures against simulated lightning strikes demonstrated high resilience due to their high electrical conductivity both in-plane and in through-thickness directions, with no significant damages, e.g., fiber breakage, resin evaporation, or delamination. High-temperature epoxy helped to improve the performance of the CFRP against the lightning strikes. |
| FILED | Tuesday, August 10, 2021 |
| APPL NO | 17/398063 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 70/30 (20130101) B29C 70/205 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2063/00 (20130101) Wind Motors F03D 80/30 (20160501) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042718 | Liu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (UTRF) (Knoxville, Tennessee) |
| ASSIGNEE(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (UTRF) (Knoxville, Tennessee) |
| INVENTOR(S) | Xiaobing Liu (Oak Ridge, Tennessee); Ming Qu (West Lafayette, Indiana); Joseph K. Warner (San Jose, California); Liang Shi (West Lafayette, Indiana) |
| ABSTRACT | Methods and apparatus are disclosed for high-efficiency thermal storage with a fluid-filled “battery” tank positioned within a fluid-filled “reservoir” tank. Fluid loops couple the tanks to a heat pump and a building. The heat pump can charge the battery tank or deliver thermal energy (cold or heat) to a building, using the reservoir tank or ambient air as a thermal energy source. The battery tank can discharge energy to the building jointly with the heat pump or, at periods of peak electricity usage, with the heat pump switched off. Operating modes allow significant savings in electricity usage and mitigate the “duck curve.” Low duty cycle usage of the reservoir enables efficient underground thermal storage with less digging than conventional geothermal technologies. Additional efficiency is achieved with phase change materials installed inside a tank or in a tank wall, providing temperature regulation. Control methods are disclosed. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 17/434264 |
| CURRENT CPC | Fluid Heaters, e.g Water or Air Heaters, Having Heat Generating Means, in General F24H 4/04 (20130101) Original (OR) Class Refrigeration Machines, Plants or Systems; Combined Heating and Refrigeration Systems; Heat-pump Systems F25B 30/02 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/021 (20130101) F28D 20/0034 (20130101) F28D 2020/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042721 | Podgorney |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert K. Podgorney (Idaho Falls, Idaho) |
| ABSTRACT | A system for power generation from renewable energy, comprising a heat exchanger within a subterranean formation. The heat exchanger comprises a casing at an upper portion of the wellbore, a tubular member extending through the casing to a lower portion of the wellbore, and fins in fluid communication with the casing and with the tubular member, the fins each comprising a volume defined by surfaces of the subterranean formation and configured to receive a fluid from the casing. Related longitudinal finned heat exchangers and methods of storing thermal energy within a subterranean formation are also disclosed. |
| FILED | Tuesday, August 03, 2021 |
| APPL NO | 17/444302 |
| CURRENT CPC | Geothermal Collectors; Geothermal Systems F24T 10/17 (20180501) Original (OR) Class Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 7/12 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/16 (20130101) F28F 2215/06 (20130101) F28F 2250/106 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044830 | Yacout et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Abdellatif M. Yacout (Naperville, Illinois); Sumit Bhattacharya (Darien, Illinois) |
| ABSTRACT | Fuel pellets can include a fission material powder, a protective layer coated on the fission material powder, and an oxidation diffusion barrier coated on the protective layer, with the protective layer and oxidation diffusion barrier being formed through ALD to achieve infiltration of the coatings within the fuel pellets. |
| FILED | Wednesday, August 05, 2020 |
| APPL NO | 16/986180 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/34 (20130101) C23C 16/45525 (20130101) C23C 28/34 (20130101) C23C 28/042 (20130101) Nuclear Reactors G21C 3/047 (20190101) G21C 3/626 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045232 | Sampayan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Opcondys, Inc. (Manteca, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen E. Sampayan (Manteca, California); Kristin C. Sampayan (Manteca, California) |
| ABSTRACT | Devices, methods and techniques are disclosed to interrupt a fault current in a high-voltage direct-current circuit. In one example aspect, a device includes a mechanical switch including a pair of contacts configured to be positioned apart upon activation of the circuit breaker, and a photoconductive component connected in parallel with the mechanical switch. The photoconductive component is configured to establish a current upon activation of the circuit breaker. The photoconductive component comprises a crystalline material positioned to receive a pulsed light signal from a laser light source, and a pair of electrodes coupled to the crystalline material and configured to allow an electric field to be established across the crystalline material to generate the current. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397699 |
| CURRENT CPC | Electric Switches; Relays; Selectors; Emergency Protective Devices H01H 89/00 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/161 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045337 | Zeng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UChicago Argonne, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaoqiao Zeng (Naperville, Illinois); Khalil Amine (Oakbrook, Illinois); Jun Lu (Naperville, Illinois); Yuanyuan Guo (Westmont, Illinois) |
| ABSTRACT | A metal-air battery includes an anode; a low-dimensional catalyst cathode; and an electrolyte; wherein: the low-dimensional catalyst cathode comprises a functional metal layer on a carbon support overcoated with a catalyst layer; the electrolyte comprises an aprotic solvent that is an ether-based solvent, a fluorinated ether-based solvent, an oligo (ethylene oxide) solvent, or a mixture of any two or more thereof; and the electrolyte is free of carbonate solvents. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988279 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/926 (20130101) Original (OR) Class H01M 4/8871 (20130101) H01M 12/02 (20130101) H01M 12/08 (20130101) H01M 2004/8689 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045359 | Nanda et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jagjit Nanda (Knoxville, Tennessee); Guang Yang (Ferragut, Tennessee); Tomonori Saito (Knoxville, Tennessee); Frank M. Delnick (Maryville, Tennessee) |
| ABSTRACT | A solid electrolyte (SE) composition comprising: (i) a crosslinked organic polymer containing at least one of oxygen and nitrogen atoms; (ii) an inorganic component having a metal oxide or metal sulfide composition and which is distributed throughout the crosslinked organic polymer and interacts by hydrogen bonding with the crosslinked organic polymer; and (iii) metal ions selected from the group consisting of lithium, sodium, potassium, magnesium, calcium, zinc, and aluminum. Also described herein are solid-state batteries comprising: a) an anode; (b) a cathode; and (c) the solid electrolyte composition described above. Also described herein is a method for producing the SE composition, comprising: a) homogeneously mixing the following components: (i) an organic polymer; (ii) an inorganic component; (iii) metal ions, and (iv-b) a low-boiling solvent functioning to dissolve components (i) and (iii); (b) crosslinking the organic polymer to produce a crosslinked organic polymer; and (c) removing the low-boiling solvent. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397233 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/0525 (20130101) H01M 10/0565 (20130101) Original (OR) Class H01M 2300/0082 (20130101) H01M 2300/0085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220045374 | Pan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| ASSIGNEE(S) | UCHICAGO ARGONNE, LLC (Chicago, Illinois) |
| INVENTOR(S) | Lei Pan (Chicago, Illinois); Tinuade Ololade Folayan (Chicago, Illinois); Jeffrey S. Spangenberger (Naperville, Illinois); Bryant J. Polzin (Deerfield, Illinois) |
| ABSTRACT | Method of separating individual cathode active materials from a mixture of cathode active materials by froth flotation has been developed. They are based on using appropriate chemical reagents that selectively hydrophobize individual cathode active materials to be recovered, so that they can be collected by air bubbles used in flotation and separated from other mixtures. The chemical reagents are amphiphilic molecules with specialized head groups have a strong affinity to metal elements on surfaces of cathode materials. This method enables a separation of individual cathode active material from a mixture of cathode active materials. |
| FILED | Tuesday, August 04, 2020 |
| APPL NO | 16/985028 |
| CURRENT CPC | Flotation; Differential Sedimentation B03D 1/023 (20130101) Non-metallic Elements; Compounds Thereof; C01B 25/45 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 53/42 (20130101) C01G 53/44 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 10/54 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20220040621 | DICICCO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Signature Science, LLC (Charlottesville, Virginia); Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph A. DICICCO (Cape May Court House, New Jersey); Paul M. FLANIGAN, IV (Marlton, New Jersey); John BRADY (Medford, New Jersey); Barry SMITH (Egg Harbor City, New Jersey) |
| ABSTRACT | Disclosed is a filter conditioning unit for cleaning and conditioning high-volume sampling (HVS) filters. The unit includes, among other elements, a filter tray suitable for holding one or more HVS filters, a manifold in which the filter tray is inserted, and an optional enclosure for safety. The manifold is suitable for heating the filter tray and filters therein to a desired temperature while purge gas is introduced to the manifold. Also described herein is a method of using the filter conditioning unit. |
| FILED | Thursday, August 05, 2021 |
| APPL NO | 17/395138 |
| CURRENT CPC | Separation B01D 46/0009 (20130101) B01D 46/44 (20130101) B01D 46/0063 (20130101) Original (OR) Class B01D 46/4227 (20130101) B01D 53/14 (20130101) B01D 2271/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040622 | DiCicco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Signature Science, LLC (Charlottesville, Virginia); Government of The United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph A. DiCicco (Cape May Court House, New Jersey); Paul M. Flanigan, IV (Marlton, New Jersey); David Perry (Austin, Texas); John Brady (Medford, New Jersey); Barry Smith (Egg Harbor City, New Jersey) |
| ABSTRACT | Disclosed is a thermal desorber assembly for desorbing substances collected on a high-volume sampling (HVS) filter. The assembly includes, among other elements, a filter holder for securing a HVS filter within the assembly, a desorber body, and an insulating enclosure. The design of the thermal desorber assembly is such that it can accommodate a variety of different types of HVS filter media. Also described herein is a system comprising the thermal desorber assembly and method of using the assembly. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/395782 |
| CURRENT CPC | Separation B01D 46/0002 (20130101) B01D 46/0063 (20130101) Original (OR) Class B01D 46/448 (20130101) B01D 46/4263 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/2205 (20130101) G01N 2001/022 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220040648 | Dicicco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Signature Science, LLC (Charlottesville, Virginia); Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph A. Dicicco (Cape May Court House, New Jersey); Paul M. Flanigan, IV (Marlton, New Jersey); David Perry (Austin, Texas); John Brady (Medford, New Jersey); Barry Smith (Egg Harbor City, New Jersey) |
| ABSTRACT | Disclosed is a mixing chamber apparatus suitable for high-volume sampling (HVS) application. The mixing chamber apparatus includes, among other elements, inlet and outlet manifolds, a mixing chamber, and a tubing manifold for the introduction of clean, turbulent air into the mixing chamber. The inlet manifold defines a plurality of vapor ports that can be in fluid communication with one or more vapor sources to be sampled and mixed within the mixing chamber. Also described herein is a baffled mixing system that can be used alone or in combination with the disclosed mixing chamber apparatus. |
| FILED | Thursday, August 05, 2021 |
| APPL NO | 17/395191 |
| CURRENT CPC | Mixing, e.g Dissolving, Emulsifying, Dispersing B01F 3/026 (20130101) Original (OR) Class B01F 5/0606 (20130101) B01F 15/0085 (20130101) B01F 2015/0009 (20130101) B01F 2215/0037 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220044227 | Boyd et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Daniel A. Boyd (Arlington, Virginia); Kelli L. Biegger (McLean, Virginia); Chang Ellison (Arlington, Virginia); Brandon P. Gutierrez (Burke, Virginia); Jason Lim (Alexandria, Virginia) |
| ABSTRACT | In an example involving a transaction conducted between a first party using a user mobile-identification-credential device (UMD) and a second party using a relying party system (RPS), RPS receives a request from UMD for transfer of an item, requests identification information of the first party from UMD, receives, based on consent of the first party, some or all user ID information associated with a mobile identification credential (MIC) which UMD received from an authorizing party system (APS), receives verification of the received user ID information, uses the verified user ID information to verify or not verify an identity of the first party, grants the request to transfer the item in exchange for payment or another item to be transferred from the first party to the second party when the identity of the first party is verified, and denies the request when the identity of the first party is not verified. |
| FILED | Thursday, October 21, 2021 |
| APPL NO | 17/507016 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 20/326 (20200501) G06Q 20/347 (20130101) Original (OR) Class G06Q 20/3224 (20130101) G06Q 20/3226 (20130101) G06Q 20/3674 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20220039369 | SHIELS et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aaron B. SHIELS (Fort Collins, Colorado); Jonathan C. FRAGOSO (Commerce City, Colorado); Michael C. MESSAROS (Erie, Colorado) |
| ABSTRACT | Lethal wildlife traps comprising a trap compartment with an external entrance, an automatically-resetting lethal killing mechanism attached to or located within the trap container, a triggering device to actuate the lethal killing mechanism when the wildlife is positioned properly in the trap container, and an exit at the bottom of the trap container for allowing killed wildlife to fall out of the trap container to the ground or into a separate enclosure, provide economical, humane, and discreet traps for attracting and discretely killing pest species including, for example, nesting birds, rodents, and snakes; other small animals; or invertebrate species. |
| FILED | Wednesday, August 04, 2021 |
| APPL NO | 17/394052 |
| CURRENT CPC | Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 23/16 (20130101) A01M 23/24 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042027 | Thomson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | James G. Thomson (El Cerrito, California); Roger L. Thilmony (El Cerrito, California); Kasturi Dasgupta (Fremont, California); Christopher D. Dardick (Shenandoah Junction, West Virginia) |
| ABSTRACT | The present disclosure provides genetic constructs containing a promotor that is useful in driving fruit-specific expression in plants. Further provided are expression vectors, transgenic plants, and plant parts containing such genetic constructs, as well as uses thereof. |
| FILED | Friday, July 02, 2021 |
| APPL NO | 17/366517 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/825 (20130101) C12N 15/8235 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042095 | Khatib |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hasan Khatib (Fitchburg, Wisconsin) |
| ABSTRACT | Method for determining developmental fate of early embryos comprises measuring the expression level of a gene selected from the group consisting of CDKIV1C, IGF2R, MAGEL2, MKRN3, NAP1L5, NDN, PEG3, PHLDA2, TSSC4, and UBE3A genes. Also disclosed is a method for improving pregnancy rate, wherein early embryos whose expression level of the MKRN3, NDN, PEG3, PHLDA2, TSSC4, or UBE3A gene is not increased, or the expression level of the CDKIV1C, IGF2R, MAGEL2, or NAP1L5 gene is not decreased, are selected for planting into a suitable uterus for further development. Also disclosed are methods for increasing the likelihood of an early embryo to develop successfully into full-term pregnancy, wherein a suitable amount of siRNA corresponding to the PHLDA2 gene is injected into a fertilized egg which is in turn cultured further and planted into a suitable uterus. |
| FILED | Tuesday, October 26, 2021 |
| APPL NO | 17/511092 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1135 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6876 (20130101) Original (OR) Class C12Q 2600/124 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20220041268 | Ivanco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF NASA (WASHINGTON, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Thomas G. Ivanco (Yorktown, Virginia); Patrick S. Heaney (Gloucester, Virginia); Charles Chiou (Virginia Beach, Virginia) |
| ABSTRACT | A passive gust load alleviation device for an aerodynamic panel includes a free-floating aerodynamic control surface connected to the panel via a revolute joint. A counterweight is connected to the control surface. Relative to a direction of ambient airflow, the counterweight has a center of gravity forward of the axis of rotation. The counterweight is configured to passively deflect the control surface about the axis to alleviate a gust load. A vehicle includes an aerodynamic panel connected to a body and extending into ambient airflow, and the control surface and counterweight. A method for alleviating the gust load on an aircraft panel includes connecting the control panel, via the revolute joint, along a trailing edge of the panel, and during a flight of an aircraft having the panel, passively deflecting the control panel about the axis in response to an incident wind gust. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/395747 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 3/50 (20130101) B64C 5/10 (20130101) B64C 13/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042754 | Weisensee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Patricia Weisensee (St. Louis, Missouri); Mehran Abolghasemibizaki (St. Louis, Missouri); Junhui Li (St. Louis, Missouri) |
| ASSIGNEE(S) | Washington University (St. Louis, Missouri) |
| INVENTOR(S) | Patricia Weisensee (St. Louis, Missouri); Mehran Abolghasemibizaki (St. Louis, Missouri); Junhui Li (St. Louis, Missouri) |
| ABSTRACT | A passive heat switch device is disclosed that includes a casing defining a closed channel, as well as a passive thermal actuator and liquid slug positioned inside the closed channel. The closed channel includes a heat conducting region made of a heat conducting material and an insulating region made of an insulating material. The passive thermal actuator is thermally coupled to the heat conducting material of the heat conducting region and extends into the insulating region of the closed channel. The passive thermal actuator deforms when an actuator temperature falls within a switching temperature range. The liquid slug is positioned within the closed channel and contacts at least a portion of the passive thermal actuator and the closed channel and is configured to move along the closed channel between the insulating region and the thermally conductive region in response to deformation of the passive thermal actuator. |
| FILED | Tuesday, July 13, 2021 |
| APPL NO | 17/374916 |
| CURRENT CPC | Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/00 (20130101) Original (OR) Class F28F 2013/008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220043288 | Wu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Yen-Hung Wu (Pasadena, California); Stewart Sherrit (Montrose, California); Valerie Scott Kristof (Pasadena, California); Mina Rais-Zadeh (Pasadena, California); Mustafa B. Coskun (Pasadena, California) |
| ABSTRACT | Disclosed herein is a tunable diffraction grating using surface acoustic waves. In some embodiments, the tunable diffraction grating includes a piezoelectric substrate including an interdigital transducer (IDT) region and a delay line region; a plurality of IDT electrodes positioned in the IDT region, wherein the IDT electrodes are each individually addressable such that the voltage applied to each of the electrodes is phase shifted, and wherein the IDT electrodes provide the phase shifted voltage to induce surface acoustic waves in the piezoelectric substrate in a pattern which produce a grating in the delay line region. Advantageously, tunable diffraction gratings have many applications including spectrometers for orbiters and rovers to Mars. |
| FILED | Monday, August 09, 2021 |
| APPL NO | 17/397767 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/113 (20130101) Original (OR) Class G02F 2201/124 (20130101) Impedance Networks, e.g Resonant Circuits; Resonators H03H 9/25 (20130101) H03H 9/02559 (20130101) H03H 9/02881 (20130101) H03H 9/14541 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20220040970 | Zabow |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of Commerce (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gary Zabow (Boulder, Colorado) |
| ABSTRACT | A process for making an ultra-conformal microprint by ultra-conformal microprint transferring includes: disposing a transfer moiety arranged in a microstructure on a transfer substrate; disposing a glassy transfer layer on the transfer moiety; forming a glassy composite; removing the glassy composite from the transfer substrate while maintaining the microstructure of the transfer moiety in the glassy transfer layer; disposing the glassy composite on a microprint substrate; ultra-conformally covering the microprint substrate with the glassy composite by heating the glassy composite so that it flows while maintaining the microstructure of the transfer moiety in the glassy transfer layer so that the microstructure is disposed on the microprint substrate; and removing the glassy transfer layer while leaving the transfer moiety disposed in the microstructure on the microprint substrate to form the ultra-conformal microprint including the transfer moiety arranged in the microstructure on the microprint substrate. |
| FILED | Friday, August 07, 2020 |
| APPL NO | 16/988017 |
| CURRENT CPC | Printing Machines or Presses B41F 19/08 (20130101) Original (OR) Class Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 3/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042801 | WANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Yusheng WANG (Irvine, California); Andrei M. SHKEL (Irvine, California) |
| ABSTRACT | Processes and systems for adaptive pedestrian inertial navigation are provided. Configurations can adjust to various navigation scenarios, including different floor types and different gait paces. A combination of IMU data partition, principal component analysis (PCA), and artificial neural network may be used to perform the floor type detection. Floor type results may be used in the multiple-model extended Kalman filter. In each extended Kalman filter, an adaptive threshold is used for the stance phase detection to enable the detector to adjust to gait frequency without tuning design parameters during navigation. A floor type classification of high accuracy is demonstrated, and the position error in a velocity-changing navigation system using adaptive threshold is reduced. |
| FILED | Friday, August 06, 2021 |
| APPL NO | 17/395706 |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/166 (20200801) Original (OR) Class G01C 22/006 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20220040000 | Grubbs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California); The Regents of the University of California (Oakland, California); United States Government Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); The Regents of the University of California (Oakland, California); United States Government represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Robert H. Grubbs (South Pasadena, California); Marshall L. Stoller (San Francisco, California); Ying Han (Burlingame, California); Frank L. Brodie (Durham, North Carolina) |
| ABSTRACT | A surgical method of cataract fragmentation and extraction via microbubble cavitation is described. In particular, gas-filled microbubbles are injected into a lens capsule of a subject's eye, and cavitation of the microbubbles is activated by applied ultrasound energy. The ultrasound energy can be applied from an external device. The cavitation fragments cataract tissues without damaging other tissue, such as the lens capsule. Fragmented lens material is then aspirated from the lens capsule. The method can be used alone or in conjunction with other methods, such as phacoemulsification. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/509641 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 9/00745 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220041667 | Kapiloff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California); The University of Miami (Miami, Florida); The United States Government As Represented By The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael S. Kapiloff (Los Altos, California); Jeffrey L. Goldberg (Menlo Park, California) |
| ABSTRACT | Nervous system trauma and neurodegeneration including in optic neuropathies are treated by administration of an effective dose of a PDE4D3 displacing agent to promote neurite extension, neuroprotection and recovery. In some embodiments the neurons are optic neurons, including without limitation retinal ganglion cells (RGCs). A cAMP signaling compartment restricted by mAKAPα-anchored PDE4D3 directly regulates neuronal phenotype, and can be molecularly manipulated with therapeutic effect. |
| FILED | Wednesday, November 13, 2019 |
| APPL NO | 17/290174 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/4702 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Nuclear Security Administration Sites (NNSA)
| US 20220041464 | HATCHETT et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, (LasVegas, Nevada) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David W. HATCHETT (Las Vegas, Nevada); Kenneth R. CZERWINSKI (Seattle, Washington); Katherine LUEBKE (Las Vegas, Nevada); Cassara HIGGINS (Las Vegas, Nevada) |
| ABSTRACT | Described are methods for the recovery of uranium from uranium hexafluoride dissolved directly into ionic liquids. |
| FILED | Friday, March 29, 2019 |
| APPL NO | 17/438112 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 43/063 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/72 (20130101) C01P 2002/85 (20130101) C01P 2002/88 (20130101) C01P 2004/03 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220042540 | Cole et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Consolidated Nuclear Security, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert N. Cole (Knoxville, Tennessee); Kevin P. Shay (Knoxville, Tennessee); Austin L. Renfro (Knoxville, Tennessee) |
| ABSTRACT | A foreign material exclusion plug is disclosed. The foreign material plug includes a cylindrical body, a slot, and a breakaway tab. The cylindrical body includes an externally-threaded cylindrical structure. The slot is formed in the cylindrical body extending into the cylindrical body from a top surface of the cylindrical body. The breakaway tab is connected to the cylindrical body and extends outwards from the top surface. |
| FILED | Monday, August 10, 2020 |
| APPL NO | 16/988846 |
| CURRENT CPC | Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 31/021 (20130101) F16B 37/125 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 20220042506 | Wikswo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Ronald S. Reiserer (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); Dmitry A. Markov (Nashville, Tennessee); Clayton M. Britt (Franklin, Kentucky) |
| ABSTRACT | A push-pull micropump includes one or more pairs of channels configured to transfer one or more fluids, each channel pair having an aspiration channel and an injection channel; and an actuator configured to engage the one or more pairs of channels, wherein the actuator comprises a plurality of rolling members and a driving member configured such that when the driving member rotates, the plurality of rolling members rolls along the one or more pairs of channels to cause individually the one or more fluids to transfer through each channel pair simultaneously at different flowrates or the same flowrate, depending upon actuated lengths of the aspiration and injection channels of each channel pair, wherein an actuated length of a channel is defined by a length of the channel along which the plurality of rolling members rolls during a full rotation of the driving member. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/505940 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/12 (20130101) F04B 43/0054 (20130101) F04B 43/0072 (20130101) F04B 43/1253 (20130101) F04B 43/1269 (20130101) Original (OR) Class F04B 43/1292 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Non-Profit Organization (NPO)
| US 20220040290 | PERMAR et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sallie PERMAR (Durham, North Carolina); Joel COLLIER (Durham, North Carolina); Kevin O. SAUNDERS (Durham, North Carolina); Chelsea FRIES (Durham, North Carolina); Fouda Amou'ou Genevieve GINY (Durham, North Carolina) |
| ABSTRACT | The technology provides immunogenic compositions comprising HIV-1 envelopes in supramolecular nanofiber complexes, which may also comprise a T-cell helper epitopes, and methods of using these compositions for induction of immune responses. |
| FILED | Tuesday, September 24, 2019 |
| APPL NO | 17/279033 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) Original (OR) Class A61K 2039/6031 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 20220042506 | Wikswo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John P. Wikswo (Brentwood, Tennessee); Ronald S. Reiserer (Nashville, Tennessee); David K. Schaffer (Nashville, Tennessee); Dmitry A. Markov (Nashville, Tennessee); Clayton M. Britt (Franklin, Kentucky) |
| ABSTRACT | A push-pull micropump includes one or more pairs of channels configured to transfer one or more fluids, each channel pair having an aspiration channel and an injection channel; and an actuator configured to engage the one or more pairs of channels, wherein the actuator comprises a plurality of rolling members and a driving member configured such that when the driving member rotates, the plurality of rolling members rolls along the one or more pairs of channels to cause individually the one or more fluids to transfer through each channel pair simultaneously at different flowrates or the same flowrate, depending upon actuated lengths of the aspiration and injection channels of each channel pair, wherein an actuated length of a channel is defined by a length of the channel along which the plurality of rolling members rolls during a full rotation of the driving member. |
| FILED | Wednesday, October 20, 2021 |
| APPL NO | 17/505940 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) Positive-displacement Machines for Liquids; Pumps F04B 43/12 (20130101) F04B 43/0054 (20130101) F04B 43/0072 (20130101) F04B 43/1253 (20130101) F04B 43/1269 (20130101) Original (OR) Class F04B 43/1292 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20220040656 | Bromberg et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MAAT Energy Company (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leslie Bromberg (Sharon, Massachusetts); Kim-Chinh Tran (Cambridge, Massachusetts); Jorj Ian Owen (Dulles, Virginia); Jonathan Whitlow (Melbourne Beach, Florida) |
| ABSTRACT | Devices and methods for reducing the specific energy required to reform or pyrolyze reactants in plasmas operating at high flow rates and high pressures are presented. These systems and methods include 1) introducing electrons and/or easily ionized materials to a plasma reactor, 2) increasing turbulence and swirl velocity of the flows of feed gases to have improved mixing in a plasma reactor, and 3) reducing slippage from a plasma reactor system. Such plasma systems may allow plasma reactors to operate at lower temperatures, higher pressure, with improved plasma ignition, increased throughput and improved energy efficiency. In preferred embodiments, the plasma reactors are used to produce hydrogen and carbon monoxide, hydrogen and carbon, or carbon monoxide through reforming and pyrolysis reactions. Preferred feedstocks include methane, carbon dioxide, and other hydrocarbons. |
| FILED | Tuesday, February 25, 2020 |
| APPL NO | 17/433131 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 4/001 (20130101) B01J 6/008 (20130101) Original (OR) Class B01J 8/0278 (20130101) B01J 19/088 (20130101) B01J 19/126 (20130101) B01J 19/129 (20130101) B01J 19/2405 (20130101) B01J 2219/00159 (20130101) B01J 2219/0847 (20130101) B01J 2219/0849 (20130101) B01J 2219/0892 (20130101) B01J 2219/0898 (20130101) Non-metallic Elements; Compounds Thereof; C01B 3/26 (20130101) C01B 3/382 (20130101) C01B 2203/0205 (20130101) C01B 2203/0277 (20130101) C01B 2203/0861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20220045998 | Bonnell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Clayton C. Bonnell (Fairfax, Virginia); Kelley A. Sullivan (Washington, District of Columbia) |
| ABSTRACT | Methods and systems for resetting a digital credential within a digital credential based authentication system. The method includes logging a first administrative user into the digital credential system, receiving, from the first administrative user, a first portion of authentication credentials for a first customer, validating, by the first administrative user using the digital credential system, the first portion, logging a second administrative user into the digital credential system, receiving, from the second administrative user, a second portion of authentication credentials for the first customer, receiving the second portion by the second administrative user, validating, by the second administrative user using the digital credential system, the second portion; and resetting the authentication credentials based on the validation of the first portion and second portion. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/452183 |
| CURRENT CPC | Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/063 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 63/08 (20130101) Original (OR) Class H04L 63/18 (20130101) H04L 63/083 (20130101) H04L 63/102 (20130101) H04L 63/107 (20130101) H04L 63/0853 (20130101) H04L 63/0892 (20130101) H04L 2463/082 (20130101) Wireless Communication Networks H04W 12/63 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, February 10, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/details-applications-20220210.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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