FedInvent™ Patent Applications
Application Details for Thursday, May 12, 2022
This page was updated on Monday, May 16, 2022 at 09:01 PM GMT
Department of Health and Human Services (HHS)
| US 20220142135 | ACHARYA et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Soumyadipta ACHARYA (Ellicott City, Maryland); Margaret GLANCEY (Baltimore, Maryland); Adam C. GOODWIN (Baltimore, Maryland); Laura Elizabeth Schiffrin SCAVO (Bethesda, Maryland); Jewell BREY (Chapel Hill, North Carolina); Tristan FORD (Baltimore, Maryland); Collyn J. HEIER (Cambridge, Massachusetts) |
| ABSTRACT | An insect trap analysis system may detect an insect specimen on a trap mechanism of an insect trap. The insect trap analysis system may control, based on detecting the insect specimen on the trap mechanism, one or more mechanical devices to: adjust a position of the insect specimen relative to a position of an image capture device associated with the insect trap, or adjust the position of the image capture device relative to the position of the insect specimen. The insect trap analysis system may cause, while controlling the one or more mechanical devices to adjust the position of the image capture device or the position of the insect specimen, the image capture device to capture a plurality of images of the insect specimen from a plurality of different angles relative to the insect specimen, and may perform an action associated with the plurality of images. |
| FILED | Wednesday, February 19, 2020 |
| APPL NO | 17/433138 |
| CURRENT CPC | Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/026 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 20/52 (20220101) Pictorial Communication, e.g Television H04N 7/183 (20130101) Wireless Communication Networks H04W 4/029 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142484 | DiMaio et al. |
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| FUNDED BY |
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| APPLICANT(S) | SPECTRAL MD, INC. (Dallas, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | John Michael DiMaio (Dallas, Texas); Wensheng Fan (Dallas, Texas); Jeffrey E. Thatcher (Dallas, Texas); Weizhi Li (Dallas, Texas); Weirong Mo (Dallas, Texas) |
| ABSTRACT | Certain aspects relate to apparatuses and techniques for non-invasive optical imaging that acquires a plurality of images corresponding to both different times and different frequencies. Additionally, alternatives described herein are used with a variety of tissue classification applications, including assessing the presence and severity of tissue conditions, such as burns and other wounds. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 17/585346 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0064 (20130101) A61B 5/0075 (20130101) Original (OR) Class A61B 5/0205 (20130101) A61B 5/0261 (20130101) A61B 5/0295 (20130101) A61B 5/445 (20130101) A61B 5/7264 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 40/20 (20180101) G16H 50/20 (20180101) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142498 | Majumdar et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Sharmila Majumdar (Alameda, California); John Kurhanewicz (South San Francisco, California); Jeffrey C. Lotz (San Mateo, California); David S. Bradford (Sausalito, California); Kayvan Keshari (Stockton, California) |
| ABSTRACT | A completely non-invasive diagnostic toolset and method to image and localize degeneration and/or pain. Extent of degeneration is determined based on NMR spectroscopy of intervertebral disc tissue. Correlation between NMR spectral regions and at least one of tissue degeneration and pain are made. Accordingly, NMR spectroscopy is used to determine location and/or extent of at least one of degeneration or pain associated with a region of tissue, such as for example in particular disc degeneration, or discogenic pain. NMR spectral peak ratios, such as between N-Acetyl/cho and cho/carb, are acquired and analyzed to predict degree of tissue degeneration and/or pain for: tissue samples using HR-MAS spectroscopy; and larger portions of anatomy such as joint segments such as a spine, using clinical 3T MRI systems with surface head or knee coils; and tissue regions such as discs within spines of living patients using 3T MRI systems with a surface spine coil. |
| FILED | Friday, July 09, 2021 |
| APPL NO | 17/372103 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) Original (OR) Class A61B 5/4514 (20130101) A61B 5/4528 (20130101) A61B 5/4566 (20130101) A61B 5/4824 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 24/08 (20130101) G01N 33/68 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 33/00 (20130101) G01R 33/20 (20130101) G01R 33/44 (20130101) G01R 33/46 (20130101) G01R 33/48 (20130101) G01R 33/54 (20130101) G01R 33/465 (20130101) G01R 33/483 (20130101) G01R 33/4625 (20130101) G01R 33/4828 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142551 | Rottmann et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Markus Rottmann (Chicago, Illinois); Rishi K. Arora (Chicago, Illinois) |
| ABSTRACT | A method for characterizing atrial fibrillation includes determining, by a processor of a computing device and based on heart data, an earliest activation time of a heart being monitored. The method also includes determining, by the processor and based on the heart data, a latest activation time of the heart. The method also includes modeling, by the processor, the earliest activation time and the latest activation time within one or more activation time maps. The method further includes identifying, by the processor, an atrial fibrillation driver based at least in part on the one or more activation time maps. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/521545 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/361 (20210101) Original (OR) Class A61B 5/367 (20210101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142554 | Purdon et al. |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Patrick L. Purdon (Somerville, Massachusetts); Hugo Soulat (Boston, Massachusetts); Amanda M. Beck (Boston, Massachusetts); Emily P. Stephen (Boston, Massachusetts) |
| ABSTRACT | In accordance with one aspect of the disclosure, a method for estimating at least one oscillatory component of a patient brain state is provided. The method includes receiving electroencephalogram (BEG) data, fitting a space state model to the EEG data, the state space model comprising at least one oscillatory component, estimating at least one value of cross-frequency coupling of the EEG data based on the state space model, generating a report based on the at least one value of cross-frequency coupling, and outputting the report to at least one of a display and a memory. |
| FILED | Tuesday, July 16, 2019 |
| APPL NO | 17/259659 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/291 (20210101) A61B 5/374 (20210101) Original (OR) Class A61B 5/384 (20210101) A61B 2560/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142609 | Yeo et al. |
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| FUNDED BY |
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| APPLICANT(S) | Gustavo Eduardo Abella (Buenos Aires, Argentina); Ricardo Enrique Gayoso (Buenos Aires, Argentina); Wayne State University (Detroit, Michigan); National Institutes of Health (NIH) (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lami Yeo (Detroit, Michigan); Roberto Romero (Gross Pointe, Michigan); Gustavo Eduardo Abella (Buenos Aires, Argentina); Ricardo Enrique Gayoso (Buenos Aires, Argentina) |
| ABSTRACT | A method and apparatus of examining fetal hearts includes obtaining ultrasound data of a fetal heart to generate fetal heart images, displaying different marked sample images of a fetal heart and at respective cardiac phases, each marking a different feature of a fetal heart at a respective marked location, and sequentially presenting one of the different marked sample images to a user along with one of the fetal heart images that is a similar view. As each of the different marked sample images is sequentially presented, a user is prompted to mark the different feature in a respective fetal heart image based on its marked location to create a plurality of marked fetal heart images, and a geometric model of the heart is generated based on the marked fetal heart images, from which fetal echocardiography views can be extracted. The fetal echocardiography views of the fetal heart are displayed. |
| FILED | Monday, November 15, 2021 |
| APPL NO | 17/526798 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/14 (20130101) A61B 8/54 (20130101) A61B 8/461 (20130101) A61B 8/466 (20130101) A61B 8/483 (20130101) A61B 8/0866 (20130101) Original (OR) Class A61B 8/0883 (20130101) A61B 8/5223 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142613 | Alizad et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Azra Alizad (Rochester, Minnesota); Mostafa Fatemi (Rochester, Minnesota); Juanjuan Gu (Rochester, Minnesota) |
| ABSTRACT | Ultrasound systems and methods are provided using mass characterization frequency methods that provide for predicting benign or malignant lesions, a response to treatment, tumor grading, and/or the expressions of immunohistochemical biomarkers, which are currently used for breast cancer classification and hormone therapy determination. The systems and methods are based on the shear wave parameter, mass characteristic frequency. The status of malignancy, treatment response, grade, and/or each immunohistochemical biomarker may be determined based on a corresponding mass characteristic frequency threshold. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/466073 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/085 (20130101) A61B 8/485 (20130101) A61B 8/4488 (20130101) A61B 8/5215 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142919 | Marco-Dufort et al. |
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| FUNDED BY |
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| APPLICANT(S) | NANOLY BIOSCIENCE, INC. (Denver, Colorado) |
| ASSIGNEE(S) | Nanoly Bioscience, Inc. (Denver, Colorado) |
| INVENTOR(S) | Bruno Marco-Dufort (Zurich, Switzerland); Mark W. Tibbitt (Zurich, Switzerland); Balaji V. Sridhar (Denver, Colorado); John R. Janczy (Denver, Colorado); David Busha (Boulder, Colorado); Margaret Best (Boulder, Colorado) |
| ABSTRACT | The present invention provides dynamically covalent polymeric hydrogel systems for encapsulating and stabilizing bioactive therapeutic agents (e.g., proteins, cells, viruses, and vaccines) from environmental stressors, obviating standard refrigeration requirements, and decreasing transportation and storage costs of temperature-sensitive biomolecules. Described herein are dynamic polymeric hydrogel compositions comprising a therapeutic agent and a combination of phenylboronic acid- and 1,2-diol-modified multi-arm polyethylene glycol (PEG) polymer backbones. Methods of encapsulating and stabilizing bioactive therapeutic agents within the dynamic polymeric hydrogel compositions are also provided. Also described are methods for releasing stabilized therapeutic agents from hydrogel encapsulation. The covalently adaptable hydrogel release systems allow for discretionary administration of temperature-sensitive therapeutic agents, as well as the parenteral administration of highly concentrated amounts of therapeutic agents. |
| FILED | Thursday, March 05, 2020 |
| APPL NO | 17/433736 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/06 (20130101) Original (OR) Class A61K 35/54 (20130101) A61K 35/761 (20130101) A61K 38/47 (20130101) A61K 38/52 (20130101) A61K 38/191 (20130101) A61K 38/208 (20130101) A61K 38/465 (20130101) A61K 39/3955 (20130101) A61K 47/34 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142937 | Zhang |
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| FUNDED BY |
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| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Huang-Ge Zhang (Louisville, Kentucky) |
| ABSTRACT | Provided are methods for preventing and/or treating oral diseases, disorders, and/or conditions. In some embodiments, the methods relate to administering to the oral cavity of a subject in need thereof a composition that includes an effective amount of ginger-derived exosome-like nanoparticles (GELNs) or a biologically active component thereof. Also provided are methods for preventing and/or treating periodontitis, methods for reducing growth of and/or pathogenicity of microorganisms in the oral cavities of subjects, methods for reducing microorganismal motility, and methods for reducing bone loss in the oral cavities of subjects associated with infection with microorganisms. Also provided are compositions that can be employed in the disclosed methods. |
| FILED | Monday, March 02, 2020 |
| APPL NO | 17/435650 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 9/5176 (20130101) Original (OR) Class A61K 36/9068 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142946 | Harrelson et al. |
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| APPLICANT(S) | Pacific University. (Forest Grove, Oregon) |
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| INVENTOR(S) | John P. Harrelson (Forest Grove, Oregon); Deepa A. Rao (Beaverton, Oregon) |
| ABSTRACT | Compounds, compositions, and methods of use of such compounds and compositions are provided for reducing human dependency to nicotine. In one example, a method of treating an individual with an addiction to nicotine comprises administering to the individual a compound that is a structural analog of trans-cinnamaldehyde. Based on the administration, a rate at which nicotine is metabolized may be reduced, which in turn may reduce a desire for the individual to consume nicotine-containing products. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 17/649328 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0053 (20130101) A61K 31/11 (20130101) Original (OR) Class A61K 31/465 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/34 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142948 | Regev et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Boston, Massachusetts); The Brigham and Women's Hospital, Inc. (Boston, Massachusetts); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Aviv Regev (Cambridge, Massachusetts); Chao Wang (Boston, Massachusetts); Vijay K. Kuchroo (Boston, Massachusetts); Nir Yosef (Oakland, California); Allon Wagner (Oakland, California); Johannes Fessler (Boston, Massachusetts) |
| ABSTRACT | The subject matter disclosed herein is generally directed to modulation of Th17 differentiation and pathogenicity by use of metabolic targets. The metabolic targets are the molecules of the polyamine pathway or glycolysis pathway. Modulation of the polyamine pathway can shift Th17 pathogenicity and shift the transcriptome of Th17 cells to a Treg or Th1 transcriptome. The polyamine analogue DFMO can be used to modulate an inflammatory response. Inhibitors of enzymes in the glycolysis pathway can shift Th17 pathogenicity. |
| FILED | Wednesday, March 18, 2020 |
| APPL NO | 17/440282 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/132 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 9/0071 (20130101) C12N 9/88 (20130101) C12N 9/1029 (20130101) C12N 15/111 (20130101) C12N 2506/11 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142973 | ANDROPHY et al. |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana); KOVINA THERAPEUTICS, INC. (Indianapolis, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | ELLIOT J. ANDROPHY (Indianapolis, Indiana); SAMY MEROUEH (Carmel, Indiana); ZHIJIAN LU (Indianapolis, Indiana); Anne RIETZ (Indianapolis, Indiana) |
| ABSTRACT | Compositions and methods are provided for treating HPV infections including pre-malignant and cancers. Compounds that specifically bind to the HPV E6 protein and inactivate the protein are disclosed. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579069 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0002 (20130101) A61K 31/381 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142991 | PAN |
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| APPLICANT(S) | CHILDREN'S HOSPITAL MEDICAL CENTER (Cincinnati, Ohio) |
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| INVENTOR(S) | Dao PAN (Cincinnati, Ohio) |
| ABSTRACT | Methods for improving at least one neurological function in a subject that has or is suspected of having a neurologic lysosomal storage disorder using a rapamycin compound. Also provided herein are treatment of such a neurologic lysosomal storage disorder with the rapamycin compound. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 17/438024 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143023 | ROBICHAUX et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Jacqulyne ROBICHAUX (Houston, Texas); Monique NILSSON (Houston, Texas); John V. HEYMACH (Houston, Texas) |
| ABSTRACT | The present disclosure provides methods of treating cancer in a patient determined to have an EGFR and/or HER2 exon 20 mutation, such as an insertion mutation, by administering a third-generation tyrosine kinase inhibitor, such as poziotinib or afatinib. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 17/599969 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/436 (20130101) A61K 31/517 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143028 | Oro |
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| FUNDED BY |
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| APPLICANT(S) | Anthony E. ORO (Stanford, California); Cancer Research Technology LTD (London, United Kingdom) |
| ASSIGNEE(S) | Cancer Research Technology LTD (London, United Kingdom) |
| INVENTOR(S) | Anthony E. Oro (Stanford, California) |
| ABSTRACT | Methods for treating hedgehog pathway-dependent cancers are provided. Aspects of the methods include the inhibition of hedgehog pathway-dependent cancer growth, proliferation, or metastasis that is promoted by hedgehog pathway signaling. In particular, methods of treating hedgehog pathway-dependent cancers with inhibitors of atypical protein kinase C iota are disclosed. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 17/598719 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/167 (20130101) A61K 31/519 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143033 | Patidar et al. |
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| APPLICANT(S) | New Mexico Tech University Research Park Corporation (Socorro, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Praveen Patidar (Socorro, New Mexico); Talysa Viera (Socorro, New Mexico) |
| ABSTRACT | Disclosed herein are methods of treating a cancer that overexpresses NQO1 comprising administering KP372-1. In some embodiments, KP372-1 is administered with a polymerase inhibitor. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 17/523002 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/53 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143035 | STETSON et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Brewster STETSON (Seattle, Washington); Katelyn BURLEIGH (Seattle, Washington); Joanna MALTBAEK (Seattle, Washington) |
| ABSTRACT | The disclosure provides method and compositions for treating of an autoimmune disease or an autoinflammatory disease, including administering to a subject in need thereof an amount effective of a DNA-dependent protein kinase (DNA-PK) inhibitor and/or an inhibitor of HSPA8/HSC70. |
| FILED | Tuesday, March 03, 2020 |
| APPL NO | 17/435194 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/341 (20130101) A61K 31/404 (20130101) A61K 31/519 (20130101) A61K 31/711 (20130101) A61K 31/4184 (20130101) A61K 31/5375 (20130101) A61K 31/5377 (20130101) Original (OR) Class A61K 31/7105 (20130101) A61K 39/3955 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 2800/52 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143056 | Gordts et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Philip Gordts (San Diego, California); Ariane Pessentheiner (Graz, Austria); Lars Bode (San Diego, California) |
| ABSTRACT | The disclosure provides for therapies and methods to treat atherosclerosis and/or hyperlipidemia, and complications resulting therefrom, with compositions that comprise therapeutically effective amounts of one or more human milk oligosaccharides. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/584129 |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/125 (20160801) Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/20 (20130101) A61K 9/0095 (20130101) A61K 9/4808 (20130101) A61K 31/702 (20130101) A61K 31/7016 (20130101) Original (OR) Class A61K 35/20 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/06 (20180101) A61P 9/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143066 | Spector et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cold Spring Harbor Laboratory (Cold Spring Harbor, New York); Ionis Pharmaceuticals, Inc. (Carlsbad, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David L. Spector (Cold Spring Harbor, New York); Sarah Daniela Diermeier (Centerport, New York); Frank Rigo (Carlsbad, California); C. Frank Bennett (Carlsbad, California); Susan M. Freier (San Diego, California); Gayatri Arun (Huntington, New York); Kung-Chi Chang (Cold Spring Harbor, New York) |
| ABSTRACT | Provided herein are methods, compounds, and compositions for reducing expression of a MaTAR in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate breast cancer in an individual in need. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 17/348125 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/175 (20130101) A61K 31/712 (20130101) A61K 31/713 (20130101) Original (OR) Class A61K 31/7125 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143067 | STRAUSS et al. |
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| FUNDED BY |
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| APPLICANT(S) | Virginia Commonwealth University (Richmond, Virginia); The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jerome F. STRAUSS (Richmond, Virginia); Janette M. MCALLISTER (Richmond, Virginia) |
| ABSTRACT | Methods for the diagnosis and treatment of DENND1A. V2 related disorders, such as PCOS, are provided. In particular, microRNAs which are upregulated or downregulated in DENND1A. V2 related disorders and methods for using the same are provided. |
| FILED | Thursday, February 20, 2020 |
| APPL NO | 17/431887 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/7105 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 15/08 (20180101) Peptides C07K 16/18 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) C12Q 1/6883 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143090 | Fuchs et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltmore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ephraim Joseph Fuchs (Owings Mills, Maryland); Heather Jill Symons (Annapolis, Maryland); Lode Swinnen (Lutherville, Maryland) |
| ABSTRACT | The invention provides methods and compositions for administration of allogeneic lymphocytes as an exogenous source of CD4+ T cell help for endogenous, tumor-reactive CD8+ T cells. Depletion of CD8+ T cells from the donor lymphocyte infusion reduces the risk of sustained engraftment and graft-versus-host disease. Removal of regulatory T cells from the infused population may augment the ability of non-regulatory T cells to provide help for endogenous effectors of anti-tumor immunity. Allogeneic T cell therapy is typically given in the context of allogeneic stem cell transplantation, in which the patient receives highly immunosuppressive conditioning followed by an infusion of a stem cell graft containing unselected populations of mature T cells. In the treatment described here, the graft is engineered to minimize the possibility of sustained donor cell engraftment, and the anti-tumor effector T cells derive from the host. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/525714 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/185 (20130101) A61K 31/664 (20130101) A61K 35/17 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143093 | BHATNAGAR et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Parijat BHATNAGAR (Belmont, California); Marvin A. SSEMADAALI (Menlo Park, California) |
| ABSTRACT | An example genetically engineered effector cell comprises an exogenous polynucleotide sequence that includes a receptor element, an actuator element, and an effector element. The receptor element encodes a chimeric antigen receptor (CAR) comprising an extracellular antigen binding domain operably linked to a transmembrane domain, and an intracellular signaling domain, wherein the extracellular antigen binding domain recognizes an antigen on a surface of a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-infected cell. The actuator element encodes a transcription factor binding site that upregulates synthesis of an antiviral protein. The effector element encodes the antiviral protein operably linked to a signal peptide, wherein, in response to the antigen binding domain of the CAR binding to the antigen of SARS-CoV-2-infected cell, the engineered effector cell is configured to activate and, to synthesize and secrete the antiviral protein. |
| FILED | Thursday, January 27, 2022 |
| APPL NO | 17/586749 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) Peptides C07K 14/7051 (20130101) C07K 16/2803 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143099 | SCADDEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David T. SCADDEN (Boston, Massachusetts); Karin GUSTAFSSON (Boston, Massachusetts) |
| ABSTRACT | Described herein are methods for the restoration of T cell production in a subject in need thereof. |
| FILED | Wednesday, April 01, 2020 |
| APPL NO | 17/598963 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/28 (20130101) Original (OR) Class A61K 38/20 (20130101) A61K 38/179 (20130101) A61K 38/193 (20130101) A61K 38/195 (20130101) A61K 38/208 (20130101) A61K 38/1709 (20130101) A61K 38/1875 (20130101) A61K 38/2086 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0668 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220143133 — METHODS AND COMPOSITIONS FOR DIAGNOSIS AND PROGNOSIS OF RENAL INJURY AND RENAL FAILURE
| US 20220143133 | MCPHERSON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | ASTUTE MEDICAL, INC. (SAN DIEGO, California); UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| ASSIGNEE(S) | ASTUTE MEDICAL, INC. (SAN DIEGO, California); UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (PITTSBURGH, Pennsylvania) |
| INVENTOR(S) | PAUL MCPHERSON (ENCINITAS, California); JOHN A. KELLUM (PITTSBURGH, Pennsylvania) |
| ABSTRACT | It is an object of the present invention to provide methods and compositions for protection of subjects from acute kidney injury by treating the subject with compounds that modulate the cell cycle. Modulating the cell cycle can comprise inducing G0/G1 cell cycle arrest, and/or inducing cell cycle progression. As demonstrated below, even a single administration of a compound which induces G0/G1 cell cycle arrest can protect subjects from AKI, and may be used prophylactically in advance of, or as a treatment following, various treatments or conditions that are known to be injurious to the kidney, followed optionally by release of the arrest. Once AKI is established, cell cycle progression can be induced to increase replacement of lost and damaged cells. |
| FILED | Monday, January 24, 2022 |
| APPL NO | 17/582999 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) A61K 31/357 (20130101) A61K 31/366 (20130101) A61K 31/436 (20130101) A61K 31/437 (20130101) A61K 31/453 (20130101) A61K 31/585 (20130101) A61K 38/13 (20130101) Original (OR) Class A61K 38/55 (20130101) A61K 38/1754 (20130101) A61K 45/06 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6893 (20130101) G01N 2333/4745 (20130101) G01N 2333/8146 (20130101) G01N 2800/50 (20130101) G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143136 | Demonbreun et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexis R. Demonbreun (Mokena, Illinois); Elizabeth M. McNally (Oak Park, Illinois) |
| ABSTRACT | The present disclosure provides compositions and methods for increasing the activity of an annexin protein to treat a cellular membrane injury in a patient in need thereof. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 17/416018 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/573 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 48/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143138 | KAPILOFF et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Anchored RSK3 Inhibitors, LLC (Los Altos, California) |
| ASSIGNEE(S) | Anchored RSK3 Inhibitors, LLC (Los Altos, California) |
| INVENTOR(S) | Michael S. KAPILOFF (Los Altos, California); Jinliang LI (Palo Alto, California); Michael KRITZER (Cambridge, Massachusetts) |
| ABSTRACT | The present invention provides a method of protecting the heart from damage, by administering to a patient at risk of such damage, a pharmaceutically effective amount of a composition which inhibits the interaction of RSK3 and mAKAPβ, or the expression or activity of one or both of those molecules. This composition may be in the form of a peptide that specifically inhibits mAKAPβ binding to RSK3 or in the form of an siRNA construct which inhibits the expression of RSK3. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 17/580692 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/519 (20130101) A61K 31/713 (20130101) A61K 31/7048 (20130101) A61K 38/005 (20130101) A61K 38/45 (20130101) A61K 38/1709 (20130101) Original (OR) Class A61K 48/00 (20130101) A61K 48/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1137 (20130101) C12N 2310/14 (20130101) C12N 2750/14143 (20130101) Enzymes C12Y 207/11001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143139 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Schepens Eye Research Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dong Feng Chen (Newtonville, Massachusetts); Kin-Sang Cho (Winchester, Massachusetts); Min Ji (Boston, Massachusetts) |
| ABSTRACT | Compositions and methods for treating and/or reducing risk of development or progression of neuroinflammation and neurodegeneration, comprising HSP60 e.g., for nasal administration, and IGFBPL1, e.g., for nasal, systemic, or ocular, e.g., intravitreal, administration. |
| FILED | Tuesday, March 03, 2020 |
| APPL NO | 17/435947 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/1709 (20130101) A61K 38/1754 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) A61P 27/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143142 | Mathison et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Megumi Mathison (Houston, Texas); Todd Rosengart (Houston, Texas); Vivek P. Singh (Houston, Texas); Deepthi Sanagasetti (Pearland, Texas); Jaya Pratap Pinnamaneni (Houston, Texas); Jianchang Yang (Pearland, Texas) |
| ABSTRACT | Embodiments of the disclosure provide methods and compositions related to improving cardiomyocyte production by exposing starting cells to ETV2 and/or VEGF. The starting cells in specific embodiments are fibroblasts and/or endothelial cells, and following exposure to ETV2 and/or VEGF the resultant cells are exposed to one or more cardiomyocyte transdifferentiation factors, such as GATA4, myocyte enhancer factor-2c (Mef2c), T-box transcription factor 5 (TBX5), or a combination thereof. The produced cardiomyocytes are provided to individuals in need thereof, in particular embodiments. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 17/593286 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/34 (20130101) A61K 38/1709 (20130101) A61K 38/1866 (20130101) Original (OR) Class A61K 45/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0656 (20130101) C12N 2501/90 (20130101) C12N 2501/998 (20130101) C12N 2506/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143149 | Mirsaeidi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Miami (Miami, Florida); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mehdi Mirsaeidi (Jacksonville, Florida); Chongxu Zhang (Riverside, Illinois); Andrew V. Schally (Miami Beach, Florida); Renzhi Cai (Miami, Florida) |
| ABSTRACT | The disclosure provides a method of treating sarcoidosis, the method comprising administering a GHRH antagonist to mammalian subject in need thereof. |
| FILED | Monday, January 17, 2022 |
| APPL NO | 17/648137 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/25 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143153 | DO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Tran DO (Los Angeles, California); Robert L. MODLIN (Sherman Oaks, California); Peter C. DEDON (Boston, Massachusetts) |
| ABSTRACT | The invention relates to compositions and methods for treating an acne. In one embodiment, the invention relates to the use of an RNA inhibitor to treat an acne. |
| FILED | Monday, March 09, 2020 |
| APPL NO | 17/435541 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/66 (20130101) A61K 9/0014 (20130101) A61K 38/465 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/10 (20180101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 19/00 (20130101) Enzymes C12Y 301/27009 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143159 | Eaves-Pyles et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tonyia Eaves-Pyles (Galveston, Texas); Richard Pyles (Galveston, Texas); Bernard P. Arulanandam (San Antonio, Texas) |
| ABSTRACT | The present invention includes a composition and method for controlling an immune response in a host to a pathogenic bacterial infection comprising: identifying a subject in need of treatment for infection with a pathogenic bacteria; and providing a composition comprising recombinant Cystatin 9 (CST9), a cystatin C (CSTC), or both CST9 and CSTC, in an amount sufficient to restrain or prevent a life-threatening, unrestrained systemic inflammatory response syndrome in a host against a pathogenic bacteria. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/550098 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/12 (20130101) A61K 38/57 (20130101) Original (OR) Class A61K 45/06 (20130101) A61K 47/60 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 29/00 (20180101) A61P 31/00 (20180101) A61P 31/04 (20180101) Technologies for Adaptation to Climate Change Y02A 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143171 | Tang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MicroVAX, LLC (Warrenton, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yucheng Tang (San Diego, California); Albert B. Deisseroth (Potomac, Maryland) |
| ABSTRACT | Provided are methods of generating an immune response to any of various antigens including foreign antigens such as infectious agent antigens. In general, the method comprises administering an expression vector encoding a transcription unit encoding a secretable fusion protein, the fusion protein containing the foreign antigen and CD40 ligand and also administering the encoded fusion protein. In another approach, an immune response to the foreign antigen is elicited using the encoded fusion protein without administering the vector. The invention methods may be used to immunize an individual against an infectious agent such as influenza virus. Methods of obtaining an immune response in older individuals also is described. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/391103 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 2039/575 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143174 | OGEMBO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California) |
| INVENTOR(S) | Javier Gordon OGEMBO (Duarte, California); Lorraine Zvichapera MUTSVUNGUMA (Duarte, California); David H. MULAMA (Duarte, California); Murali MUNIRAJU (Duarte, California) |
| ABSTRACT | Disclosed are vaccine compositions comprising a single KSHV-LP comprising two or more KSHV glycoproteins and/rl or one or more T cell antigens and methods of preventing or treating KSHV infections using the vaccine compositions. Also disclosed is an expression system or a single expression vector for co-expressing two or more KSHV glycoproteins simultaneously to generate a vaccine comprising a single virus-like particle. The expression system may include a single plasmid inserted with two or more nucleic acid sequences that encode two or more KSHV glycoproteins linked by one or more linking sequences such that the KSHV glycoproteins are co-expressed simultaneously. |
| FILED | Friday, February 21, 2020 |
| APPL NO | 17/431856 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/17 (20130101) A61K 39/245 (20130101) Original (OR) Class A61K 2039/5258 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/22 (20180101) Peptides C07K 14/005 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2710/16423 (20130101) C12N 2710/16434 (20130101) C12N 2760/18134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143183 | TRAUNER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | New York University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dirk TRAUNER (New York, New York); Martin REYNDERS (Nordstrand, Germany); Bryan MATSUURA (San Francisco, California); Marleen BEROUTI (Munich, Germany); Michele PAGANO (New York, New York) |
| ABSTRACT | Provided are compounds, which may be referred to as PHOTACs (photoswitchable proteolysis targeting chimeras), and compositions, kits, and methods of making and using PHOTACs. PHOTACs have one or more E3 ligase ligand(s), one or more photoswitchable group(s), optionally, one or more linker(s), and one or more ligand(s) for a target protein. PHOTACs may be suitable for use in methods to treat diseases, such as, for example, cancer. PHOTACs may also be suitable for use in methods to induce selective degradation of a target protein. |
| FILED | Monday, February 24, 2020 |
| APPL NO | 17/432750 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 41/0042 (20130101) Original (OR) Class A61K 47/55 (20170801) A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143196 | Cai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Minying Cai (Tucson, Arizona); Victor J. Hruby (Tucson, Arizona); Yang Zhou (Tucson, Arizona) |
| ABSTRACT | Ligand-drug conjugates for targeted melanoma therapies are disclosed herein. A ligand is conjugated to a cytotoxic cancer drug through a cleavage linker. The ligand can bind to an overexpressed receptor on a cancer cell, resulting in selectivity. This allows the drug to enter a cancer cell selectively and release the drug within that specific cancer cell. Such therapies provide selectivity to melanoma through a ligand that targets the MC1R receptor, which is highly expressed in 80% of malignant melanomas. The ligand-drug conjugates can be used to deliver a wide range of cytotoxic cancer drugs selective to melanoma cells which may solve the drug resistance problem of melanoma in current therapies. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579237 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 47/55 (20170801) Original (OR) Class A61K 47/64 (20170801) A61K 47/545 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143198 | HE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Chuan HE (Chicago, Illinois); Tong WU (Chicago, Illinois); Pingluan WANG (Chicago, Illinois) |
| ABSTRACT | Embodiments are directed to therapeutic, diagnostic, or functional complexes comprising a kethoxal derivative. |
| FILED | Friday, May 22, 2020 |
| APPL NO | 17/595477 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/121 (20130101) A61K 47/55 (20170801) A61K 47/549 (20170801) A61K 47/557 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143199 | BLAKE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tim R. BLAKE (Palo Alto, California); Paul WENDER (Palo Alto, California); Robert M. WAYMOUTH (Palo Alto, California); Ronald LEVY (Palo Alto, California); Ole Audun Werner HAABETH (Palo Alto, California); Rebecca MCCLELLAN (Palo Alto, California); Adrienne SALLETS (Palo Alto, California) |
| ABSTRACT | There are provided herein, inter alia, cationic amphipathic polymers, complexes, and compositions comprising same, and methods for their use including for the delivery of therapeutic, diagnostic and imaging agents, including nucleic acids, into a cell. The complexes, compositions and methods may facilitate delivery and targeted release of the therapeutic, diagnostic and imaging agents to particular cell types and tissues. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 17/427362 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/007 (20130101) A61K 47/549 (20170801) A61K 47/593 (20170801) Original (OR) Class A61K 48/0041 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/028 (20130101) C08G 73/0293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143210 | Olson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington); University of Washington (Seattle, Washington) |
| INVENTOR(S) | James Olson (Seattle, Washington); Eric Nealy (Seattle, Washington); Cole DeForest (Seattle, Washington); Kenneth Brasel (Seattle, Washington) |
| ABSTRACT | Methods and compositions for treatment of malignancies are provided. The methods utilize implantation of engineered, programmable hydrogel depots capable of long-term molecule release into close proximity of the tumor. By providing gradients of immune cell chemokines and releasing immune checkpoint inhibitors, the hydrogel implants are effective at elimination of tumor cells via immune cell-mediated cell death. |
| FILED | Thursday, February 27, 2020 |
| APPL NO | 17/434390 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/60 (20170801) A61K 47/65 (20170801) A61K 47/6903 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/521 (20130101) C07K 16/2803 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143211 | MESSERSMITH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); LANKENAU INSTITUTE FOR MEDICAL RESEARCH (Wynnewood, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Phillip B. MESSERSMITH (Berkeley, California); Jing CHENG (Berkeley, California); Ellen HEBER-KATZ (Wynnewood, Pennsylvania) |
| ABSTRACT | Disclosed herein are PEG-DPCA conjugates having multiple hydrophobic DPCA groups at one or both terminal ends of a PEG compound and compositions thereof and methods of using thereof for tissue regeneration and/or cellular repair (e.g., wound healing). |
| FILED | Wednesday, March 11, 2020 |
| APPL NO | 17/437579 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/60 (20170801) A61K 47/6903 (20170801) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143213 | Asokan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Aravind Asokan (Durham, North Carolina); Zachary Elmore (Durham, North Carolina) |
| ABSTRACT | The present disclosure provides, in part, compositions and methods for transient removal of neutralizing antibodies directed to AAV vectors. Such compositions and methods expand the patient cohort eligible for gene therapy and also for redosing/re-administration of AAV in patients previously treated with AAV vectors. |
| FILED | Tuesday, January 28, 2020 |
| APPL NO | 17/425765 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/6472 (20130101) C12N 15/86 (20130101) C12N 2750/14143 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143214 | Deverman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts) |
| INVENTOR(S) | Benjamin E. Deverman (Cambridge, Massachusetts); Qin Huang (Cambridge, Massachusetts); Ken Y. Chan (Cambridge, Massachusetts) |
| ABSTRACT | Methods for screening for an adeno-associated virus (AAV) capsid protein that can bind to a target protein (e.g., Ly6 protein) and related compositions are provided in aspects of the disclosure. |
| FILED | Thursday, January 30, 2020 |
| APPL NO | 17/427213 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) C12N 2750/14122 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) C12N 2810/6027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143219 | BORDEY et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Angelique BORDEY (Guilford, Connecticut); Lawrence HSIEHI (West Hartford, Connecticut); Jianbing ZHOU (New Haven, Connecticut) |
| ABSTRACT | In various aspects and embodiments the invention provides a method of treating epilepsy in a subject in need thereof the method comprising contacting a target cell of the subject with an effective amount of an HCN4 disrupting agent. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 17/436165 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) A61K 48/0016 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 15/1138 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143220 | Choi et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Washington University (St. Louis, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kyunghee Choi (St. Louis, Missouri); Ashraf Ul Kabir (St. Louis, Missouri); Karen Krchma (St. Louis, Missouri) |
| ABSTRACT | Among the various aspects of the present disclosure is the provision of compositions and methods for modulating MYCT1. An aspect of the present disclosure provides for a method of regulating tumor angiogenesis (anti-angiogenesis, Myct1-targeted vascular control) and/or immunostimulation, which inhibit tumor growth, in a subject. The present disclosure provides methods to quantify MYCT1 to predict responsiveness of a subject having a cancer or tumor to a treatment, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventions. |
| FILED | Tuesday, October 19, 2021 |
| APPL NO | 17/451428 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0066 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143270 | VEISEH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | William Marsh Rice University (Houston, Texas) |
| ASSIGNEE(S) | William Marsh Rice University (Houston, Texas) |
| INVENTOR(S) | Omid VEISEH (Houston, Texas); Bagrat GRIGORYAN (Houston, Texas); Daniel Warren SAZER (Houston, Texas); Siavash PARKHIDEH (Houston, Texas); Jordan MILLER (Houston, Texas); Sudip MUKHERJEE (Houston, Texas) |
| ABSTRACT | The disclosure describes new devices and methods for vascularizing devices and methods for implanted diagnostics and therapeutics. The present disclosure provides, in certain embodiments, a device containing a degradable shell and a non-degradable core. In certain embodiments, the non-degradable core can include encapsulated therapeutic cells and/or biosensors, wherein the degradable shell serves as a scaffold for blood vessel growth, resulting in enhanced blood flow to the cells and/or biosensors. |
| FILED | Monday, February 17, 2020 |
| APPL NO | 17/429384 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/686 (20130101) A61B 5/4851 (20130101) Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/0077 (20130101) A61F 2002/0086 (20130101) A61F 2250/0031 (20130101) A61F 2250/0068 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) A61L 27/54 (20130101) A61L 27/3834 (20130101) Original (OR) Class A61L 2300/256 (20130101) A61L 2300/414 (20130101) A61L 2300/604 (20130101) A61L 2430/04 (20130101) A61L 2430/34 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143272 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher S. Chen (Newton, Massachusetts); Sangeeta N. Bhatia (Lexington, Massachusetts); Linqing Li (Boston, Massachusetts); Jinling Yang (Boston, Massachusetts); Jeroen Eyckmans (Boston, Massachusetts) |
| ABSTRACT | Synthetic polymers, e.g., synthetic heparin mimetics, are provided, including hydrogel compositions incorporating the synthetic polymers. Methods of making and using the synthetic polymers are also provided. |
| FILED | Wednesday, July 14, 2021 |
| APPL NO | 17/376138 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/20 (20130101) A61L 27/54 (20130101) A61L 27/507 (20130101) Original (OR) Class A61L 2300/414 (20130101) A61L 2430/36 (20130101) Polysaccharides; Derivatives Thereof C08B 37/0021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143427 | Krishnaswamy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Venkataramanan Krishnaswamy (Lebanon, New Hampshire); Brian W. Pogue (Hanover, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Venkataramanan Krishnaswamy (Lebanon, New Hampshire); Brian W. Pogue (Hanover, New Hampshire) |
| ABSTRACT | The present invention relates to advanced Cherenkov-based imaging systems, tools, and methods of feedback control, temporal control sequence image capture, and quantification in high resolution dose images. In particular, the present invention provides a system and method for simple, accurate, quick, robust, real-time, water-equivalent characterization of beams from LINACs and other systems producing external-therapy radiation for purposes including optimization, commissioning, routine quality auditing, R&D, and manufacture. The present invention also provides a system and method for rapid and economic characterization of complex radiation treatment plans prior to patient exposure. Further, the present invention also provides a system and method of economically detecting Cherenkov radiation emitted by tissue and other media in real-world clinical settings (e.g., settings illuminated by visible light). |
| FILED | Monday, January 24, 2022 |
| APPL NO | 17/583167 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1067 (20130101) A61N 5/1071 (20130101) A61N 5/1075 (20130101) Original (OR) Class Measurement of Nuclear or X-radiation G01T 1/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144629 | Castor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trevor Percival Castor (Arlington, Massachusetts); Vasudevacharya Jayarama (Framingham, Massachusetts); James A. McSwiggen (Boulder, Colorado) |
| ASSIGNEE(S) | Trevor P. Castor (Woburn, Massachusetts) |
| INVENTOR(S) | Trevor Percival Castor (Arlington, Massachusetts); Vasudevacharya Jayarama (Framingham, Massachusetts); James A. McSwiggen (Boulder, Colorado) |
| ABSTRACT | The present invention pertains to the nanoencapsulation of siRNA and other biologics in phospholipid nanosomes for the improved delivery of siRNA and other biologics to targeted diseased human or animal organs and human or animal cells and apparatus and methods for making the same. In embodiments of the present invention, novel siRNAs were designed to down regulate CCR5 and CD4, based on an analysis of all known alternative transcripts for each gene from both human and monkey (Macaca mulatta) genomes. Embodiments of the present invention feature supercritical, critical and near critical fluids. Embodiments of the present invention also pertain to down regulation of CXCR4 receptor and targeting of nanosomes containing specific siRNA sequences to cells expressing those receptors on the cell surface by coating them with specific ligands. These include ligands for the receptors CCR5, CD4 and CXCR4. |
| FILED | Thursday, November 12, 2020 |
| APPL NO | 17/096738 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) Original (OR) Class B82Y 40/00 (20130101) Peptides C07K 14/5446 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144747 | Du et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lin Du (Norman, Oklahoma); Robert Cichewicz (Norman, Oklahoma); Kenneth M. Nicholas (Norman, Oklahoma); Jianlan You (New York City, New York) |
| ABSTRACT | The present disclosure, in at least certain embodiments, is directed to shikimate (shikimic acid) analogues and compositions thereof, devices and kits which contain the shikimate analogues or compositions thereof, and methods of use of the compounds and compositions for treating and neutralizing irritant or odoriferous compounds on animate or inanimate surfaces or in atmospheres. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 17/534888 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 67/327 (20130101) Original (OR) Class Heterocyclic Compounds C07D 303/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144758 | Koley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon State University (Corvallis, Oregon) |
| ASSIGNEE(S) | Oregon State University (Corvallis, Oregon) |
| INVENTOR(S) | Dipankar Koley (Corvallis, Oregon); Partha Sarathi Sheet (Ann Arbor, Michigan) |
| ABSTRACT | Multifunctional dendritic molecular probes that selectively detect Cu2+ ions via potentiometric and fluorometric techniques with low detection limits are disclosed. The selective and reversible binding of the molecules with the Cu2+ ion was used to make solid-state microsensors by incorporating the molecular probes into the carbon-based membranes as an ionophore for Cu (II). |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/525730 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 251/80 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/251 (20130101) G01N 21/643 (20130101) G01N 27/3335 (20130101) G01N 2021/6434 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144781 | FREUNDLICH et al. |
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| FUNDED BY |
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| APPLICANT(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Joel S. FREUNDLICH (New Brunswick, New Jersey); David ALLAND (New Brunswick, New Jersey); Matthew B. NEIDITCH (New Brunswick, New Jersey); Pradeep KUMAR (New Brunswick, New Jersey); Glenn CAPODAGLI (New Brunswick, New Jersey); Divya AWASTHI (New Brunswick, New Jersey); Sean EKINS (New Brunswick, New Jersey) |
| ABSTRACT | The invention provides compounds of formula I: and salts thereof wherein R1-R5 have any of the meanings described in the specification. The compounds are useful for treating bacterial infections (e.g. tuberculosis). |
| FILED | Tuesday, November 02, 2021 |
| APPL NO | 17/517569 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/4409 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/06 (20180101) Heterocyclic Compounds C07D 231/56 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144797 | McDermott et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Lee Apostle McDermott (Pittsburgh, Pennsylvania); David Koes (Pittsburgh, Pennsylvania); Samuel M. Poloyac (Pittsburgh, Pennsylvania); Shabber Mohammed (Pittsburgh, Pennsylvania) |
| ABSTRACT | This disclosure provides novel heterocyclic compounds and methods for inhibiting the enzyme CYP4. Further disclosed methods include: a method of inhibiting the biosynthesis of 20-hydroxyeicosatetraenoic acid (20-HETE) in a subject in need thereof and a method of producing neuroprotection and decreased brain damage by preventing cerebral microvascular blood flow impairment and anti-oxidant mechanisms in a subject experiencing or having experienced an ischemic event. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 17/429289 |
| CURRENT CPC | Heterocyclic Compounds C07D 231/38 (20130101) C07D 401/04 (20130101) Original (OR) Class C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 409/14 (20130101) C07D 413/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144802 | ZHAO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Crinetics Pharmaceuticals, Inc. (San Diego, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian ZHAO (San Diego, California); Yunfei ZHU (San Diego, California); Shimiao WANG (San Diego, California); Mi CHEN (San Diego, California); Joseph PONTILLO (San Diego, California) |
| ABSTRACT | Described herein are compounds that are somatostatin modulators, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders that would benefit from modulation of somatostatin activity. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 17/581740 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/10 (20180101) Heterocyclic Compounds C07D 401/04 (20130101) Original (OR) Class C07D 401/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144833 | BAZIN-LEE et al. |
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| FUNDED BY |
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| APPLICANT(S) | GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
| ASSIGNEE(S) | GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
| INVENTOR(S) | Helene G. BAZIN-LEE (Hamilton, Montana); Jay T. EVANS (Hamilton, Montana); David BURKHART (Hamilton, Montana); Michael COCHRAN (Hamilton, Montana); David A. JOHNSON (Hamilton, Montana) |
| ABSTRACT | This invention relates inter alia to novel imidazoquinoline derivatives and their use in therapy, particularly as vaccine adjuvants. |
| FILED | Monday, January 24, 2022 |
| APPL NO | 17/582176 |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144845 | SALVINO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Drexel University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Joseph M. SALVINO (Chester Springs, Pennsylvania); Xin FENG (Jiulongpo District, China PRC); Alessandro FATATIS (Penn Valley, Pennsylvania); Fei SHEN (Philadelphia, Pennsylvania); Olimpia MEUCCI (Penn Valley, Pennsylvania) |
| ABSTRACT | The disclosure provides compounds of formula (II) having the structure: Compounds of formula (II) are fractalkine receptor agonists and useful in treating, preventing or minimizing metastasis in a subject diagnosed with cancer. The compounds of the disclosure are further useful in treating central nervous system diseases (such as, but not limited to, HIV Associated Neurocognitive Disorders (HAND), and/or Alzheimer's disease), pain, inflammation (such as, but not limited to, arthritis), cardiovascular disease (such as, but not limited to, undesired vascular smooth muscle proliferation, atherosclerosis, coronary vascular endothelial dysfunction, and/or coronary artery disease), and/or multiple sclerosis. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/583554 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/337 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Heterocyclic Compounds C07D 487/04 (20130101) Original (OR) Class C07D 519/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144865 | BAZIN-LEE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
| ASSIGNEE(S) | GLAXOSMITHKLINE BIOLOGICALS SA (Rixensart, Belgium) |
| INVENTOR(S) | Helene G. BAZIN-LEE (Hamilton, Montana); Jay T. EVANS (Hamilton, Montana); David BURKHART (Hamilton, Montana); Michael COCHRAN (Hamilton, Montana); David A. JOHNSON (Hamilton, Montana) |
| ABSTRACT | This invention relates inter alia to novel imidazoquinoline derivatives and their use in therapy, particularly as vaccine adjuvants. |
| FILED | Monday, January 24, 2022 |
| APPL NO | 17/582150 |
| CURRENT CPC | Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 9/6561 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144893 | PASQUALE |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elena B. PASQUALE (San Diego, California) |
| ABSTRACT | Disclosed herein are methods and compositions engineered to modulate EphA2, including novel peptides with unexpectedly high specificity and binding affinity. The compositions described herein can be attenuated to treat subjects suffering from diseases and/or conditions. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 17/438824 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 7/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144894 | CHAKRABARTI et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (Orlando, Oklahoma); UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION , INC. (Orlando, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Debopam CHAKRABARTI (Winter Springs, Florida); Robert H. CICHEWICZ (Norman, Oklahoma); Shengxin CAI (Norman, Oklahoma); Jin Woo LEE (Norman, Oklahoma); Jennifer E. COLLINS (Osteen, Florida) |
| ABSTRACT | Novel compositions and methods for the treatment and prevention of malaria are disclosed herein. |
| FILED | Monday, January 24, 2022 |
| APPL NO | 17/582787 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) Peptides C07K 7/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144896 | Moskal et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | Joseph R. Moskal (Evanston, Illinois); Jeffrey S. Burgdorf (Evanston, Illinois) |
| ABSTRACT | Described herein are isolated peptides, compositions comprising the same, and methods of using such peptides or compositions in the treatment of depression, central nervous system disorders, and neurodevelopmental disorders. |
| FILED | Thursday, January 27, 2022 |
| APPL NO | 17/586185 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/14 (20180101) A61P 25/22 (20180101) A61P 25/24 (20180101) Peptides C07K 7/08 (20130101) C07K 7/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144904 | MA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OHIO STATE INNOVATION FOUNDATION (Columbus, Ohio) |
| ASSIGNEE(S) | OHIO STATE INNOVATION FOUNDATION (COLUMBUS, Ohio) |
| INVENTOR(S) | Jianjie MA (Powell, Ohio); Tao TAN (Columbus, Ohio); HUA ZHU (Columbus, Ohio) |
| ABSTRACT | Compositions for and methods of improving tissue function are provided. Said compositions comprise MG53 or express MG53. Said compositions can be used for improving the function of non-diseased and uninjured tissue in subjects. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/583549 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/4702 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144911 | Walter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UAB Research Foundation (Birmingham, Alabama) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark R. Walter (Birmingham, Alabama); Ashlesha Deshpande (Vestavia Hills, Alabama) |
| ABSTRACT | This invention relates to fusion proteins, nucleic acid molecules, DNA constructs, and pharmaceutical compositions comprising the same, and methods of their use in IL10 antagonism. |
| FILED | Thursday, January 30, 2020 |
| APPL NO | 17/427475 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/65 (20170801) Peptides C07K 14/5428 (20130101) Original (OR) Class C07K 2319/02 (20130101) C07K 2319/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144913 | Parekkadan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts); Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Biju Parekkadan (Cambridge, Massachusetts); Alexandra Burr (New Brunswick, New Jersey); Alfred Tamayo (West Roxbury, Massachusetts) |
| ABSTRACT | Methods and compositions for use in engineering cells to secrete therapeutic biomolecules into the blood stream in vivo in response to an individual's personal biological needs. |
| FILED | Thursday, February 27, 2020 |
| APPL NO | 17/434244 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/28 (20130101) A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/04 (20180101) A61P 3/10 (20180101) A61P 19/02 (20180101) A61P 37/06 (20180101) Peptides C07K 14/505 (20130101) C07K 14/605 (20130101) Original (OR) Class C07K 14/635 (20130101) C07K 14/7155 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144915 | WEISS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Indiana); YISSUM RESEARCH AND DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (Jerusalem, Israel) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael A. WEISS (Indianapolis, Indiana); Norman METANIS (Maghar, Israel); Orit KTORZA (Jerusalem, Israel); Gil SHOHAM (Jerusalem, Israel) |
| ABSTRACT | Disclosed herein are insulin analogues containing a pairwise substitution of cysteine at positions A6 and A11 with selenocysteine residues such that a diselenide bridge forms between these positions. The disleenide bridge of the [SecA6, SecA11] insulin analogues stabilizes the analogue relative to its [CysA6, CysA11] parent structure, providing formulations with extended shelf life at or above room temperature. Also provide are methods of treating diabetes mellitus using the [SecA6, SecA11] insulin analogue. |
| FILED | Friday, April 17, 2020 |
| APPL NO | 17/439590 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/28 (20130101) Peptides C07K 14/62 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144916 | MAYNARD et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer A. MAYNARD (Austin, Texas); Ellen WAGNER (Larkspur, Colorado); Ahlam N. QERQEZ (Cedar Park, Texas); Annalee NGUYEN (Austin, Texas) |
| ABSTRACT | Provided herein are engineered T-cell receptors (TCRs) having nanomolar affinity for the immuno-dominant pp65 peptide residing between residues 495-503 (NLV) in complex with HLA-A2*02:01. The TCRs may be membrane-hound TCRs, soluble TCRs, chimeric TCRs, or chimeric antigen receptors. Also provided are methods of using the engineered TCRs to treat diseases, monitor disease progression, monitor vaccine efficacy, and detecting NLV/A2 presentation on the surface of cells. |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 17/430319 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 47/6425 (20170801) Peptides C07K 14/7051 (20130101) Original (OR) Class C07K 16/2809 (20130101) C07K 2317/53 (20130101) C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144919 | XIAO et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | IVYGEN CORPORATION (Fort Washington, Pennsylvania) |
| ASSIGNEE(S) | IVYGEN CORPORATION (Forst Washington, Pennsylvania) |
| INVENTOR(S) | Weidong XIAO (Fort Washington, Pennsylvania); Wenjing CAO (Ardmore, Pennsylvania); Biao DONG (Philadelphia, Pennsylvania) |
| ABSTRACT | In one aspect, present invention provides a recombinant mutant human factor VIII having increased expression and/or secretion as compared to wild-type factor VIII. In certain embodiments, the recombinant factor VIII includes one or more amino acid substitution(s) selected from the group consisting of 186, Y105, A108, D115, Q117, F129, G132, H134, M147 and L152. In other aspects, the present invention provides FVIII encoding nucleic acids, FVIII-expression vectors, as well as methods of using the modified FVIII genes in the treatment of FVIII deficiencies, such as hemophilia A. |
| FILED | Monday, January 24, 2022 |
| APPL NO | 17/582289 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Peptides C07K 14/755 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144921 | HUNSPERGER et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, Maryland) |
| INVENTOR(S) | Elizabeth Anne HUNSPERGER (Guaynabo, Puerto Rico); Tesfaye Gelanew Taye (San Juan, Puerto Rico) |
| ABSTRACT | The present disclosure relates to polypeptides that specifically bind to Dengue virus non-structural protein 1, including antibodies and fragments thereof. The antibody or antigen-binding fragment thereof may specifically bind Dengue virus (DENV) serotype 4 and include: a heavy chain variable region that comprises at least one CDR amino acid sequence selected from the group consisting of: SGYNWH, YIHYSGGTNYNPSLKS, RTGTVPFAY, SYVMH, YLNPYNDDTKYNEKFKG, and GPPYALDY. The present disclosure further relates to methods of producing the polypeptides of the present disclosure, methods of diagnosing DENV, and methods of treating a DENV infection. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/583936 |
| CURRENT CPC | Peptides C07K 16/10 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/185 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144939 | RUIZ-OPAZO et al. |
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| FUNDED BY |
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| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Nelson RUIZ-OPAZO (WESTWOOD, Massachusetts); Victoria HERRERA (WESTWOOD, Massachusetts) |
| ABSTRACT | Described herein are methods of treating COVID19 from a coronavirus infection, methods of treating a subject having a coronavirus infection, methods of improving a survival rate of a subject having a coronavirus infection, methods of determining prognosis of a subject having a coronavirus infection, methods of preventing or treating organ-dysfunction or multi-organ dysfunction or failure associated with a coronavirus infection, methods of combinational therapy for a subject having a coronavirus infection, methods of reducing microthrombi formation or low flow organ-ischemia associated with a coronavirus infection by administering a DEspR inhibitor. |
| FILED | Thursday, October 14, 2021 |
| APPL NO | 17/501050 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/249 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144950 | KUCHROO et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| ASSIGNEE(S) | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (Boston, Massachusetts) |
| INVENTOR(S) | Vijay K. KUCHROO (Newton, Massachusetts); Sheng XIAO (Newton, Massachusetts); Lloyd BOD (Brookline, Massachusetts) |
| ABSTRACT | Provided herein are methods and compositions related to the targeting of Bregs for the treatment of diseases and disorders involving inappropriate suppression of B cell-mediated immune function. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 17/438545 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2818 (20130101) Original (OR) Class C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0635 (20130101) C12N 15/113 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145175 | Dai et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hongjie Dai (Cupertino, California); Yeteng Zhong (Menlo Park, California); Zhouran Ma (Stanford, California) |
| ABSTRACT | Provided are cubic-phase (α-phase) erbium (Er)-doped near-infrared-II (NIR-II)-emitting nanoparticles. In certain embodiments, the nanoparticles are near-infrared-IIb (NIR-IIb)-emitting nanoparticles. Also provided are nanoparticles having disposed thereon a layer-by-layer crosslinked polymeric hydrophilic biocompatible coating. Also provided are compositions comprising the nanoparticles of the present disclosure. Methods of using the nanoparticles, e.g., for in vivo imaging, are also provided. |
| FILED | Wednesday, March 11, 2020 |
| APPL NO | 17/435285 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0017 (20130101) A61K 49/1824 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 20/00 (20130101) Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/36 (20200101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 11/7791 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145248 | Du et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University Of Pittsburgh - of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yiqin Du (Pittsburgh, Pennsylvania); Joel Steven Schuman (New York, New York) |
| ABSTRACT | A method of preparing a functional trabecular meshwork (TM) cell from adipose-derived stem cells is provided. Methods of treating glaucoma, implanting trabecular meshwork (TM) cells, or repairing or regenerating the aqueous outflow pathway of an eye of a patient also are provided. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579153 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0048 (20130101) A61K 9/0051 (20130101) A61K 35/28 (20130101) A61K 35/30 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) Original (OR) Class C12N 2502/085 (20130101) C12N 2502/1382 (20130101) C12N 2506/1384 (20130101) C12N 2533/90 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145256 | Chancellor et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Pittsburgh - Of the Commonwealth System of Higher Education (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael B. Chancellor (Pittsburgh, Pennsylvania); Ronald Jankowski (Pittsburgh, Pennsylvania); Ryan Pruchnic (Pittsburgh, Pennsylvania); Johnny Huard (Wexford, Pennsylvania) |
| ABSTRACT | The present invention provides muscle-derived progenitor cells that show long-term survival following transplantation into body tissues and which can augment soft tissue following introduction (e.g. via injection, transplantation, or implantation) into a site of soft tissue. Also provided are methods of isolating muscle-derived progenitor cells, and methods of genetically modifying the cells for gene transfer therapy. The invention further provides methods of using compositions comprising muscle-derived progenitor cells for the augmentation and bulking of mammalian, including human, soft tissues in the treatment of various functional conditions, including malformation, injury, weakness, disease, or dysfunction. In particular, the present invention provides treatments and amelioration for urinary incontinence and other urinary tract pathologies. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 17/347696 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/12 (20130101) A61K 35/34 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0658 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145266 | INGBER et al. |
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| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Donald E. INGBER (Boston, Massachusetts); Magdalena KASENDRA (Boston, Massachusetts); Alexandra SONTHEIMER-PHELPS (Cambridge, Massachusetts); Alessio TOVAGLIERI (Somerville, Massachusetts) |
| ABSTRACT | Described herein are methods for providing an in vitro intestinal model system, e.g., using primary cells instead of cell lines and/or cancerous cells. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/539452 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0068 (20130101) C12N 5/0679 (20130101) C12N 5/0697 (20130101) Original (OR) Class C12N 2501/11 (20130101) C12N 2501/345 (20130101) C12N 2501/415 (20130101) C12N 2502/1323 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145275 | Joung et al. |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | J. Keith Joung (Winchester, Massachusetts); Benjamin Kleinstiver (Boston, Massachusetts) |
| ABSTRACT | Engineered CRISPR-Cas9 nucleases with altered and improved PAM specificities and their use in genomic engineering, epigenomic engineering, and genome targeting. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/456092 |
| CURRENT CPC | Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 2227/40 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 2319/71 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) Original (OR) Class C12N 15/63 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/111 (20130101) C12N 2310/20 (20170501) C12N 2800/22 (20130101) C12N 2800/80 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145299 | YU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hua YU (Glendora, California); Andreas HERRMANN (La Jolla, California); Marcin Tomasz KORTYLEWSKI (Monrovia, California) |
| ABSTRACT | Provided herein are, inter alia, nucleic acid compounds useful for targeting CTLA-4-expressing cells and modulating cell activity of the CTLA-4-expressing cells. The compositions provided herein may be part of pharmaceutical compositions and may be used for treatment of cancer, inflammatory diseases, infectious diseases or metabolic diseases. |
| FILED | Monday, October 25, 2021 |
| APPL NO | 17/452172 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 45/06 (20130101) A61K 47/549 (20170801) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 15/115 (20130101) C12N 15/1138 (20130101) C12N 2310/11 (20130101) C12N 2310/12 (20130101) C12N 2310/13 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2310/3519 (20130101) C12N 2320/30 (20130101) C12N 2320/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145304 | JU et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Jingfang JU (Albany, New York); Andrew FESLER (Albany, New York) |
| ABSTRACT | The present disclosure provides modified microRNA nucleic acid compositions that have one or more cytosine and/or uracil bases replaced with gemcitabine or a 5-halouracil, respectively. More specifically, the present disclosure reveals that the replacement of cytosine nucleotides within a microRNA nucleotide sequence with a gemcitabine molecule increases the ability of the microRNA to inhibit cancer progression and tumorigenesis. In addition, the present disclosure reveals that the replacement of cytosine nucleotides within a microRNA nucleotide sequence with a gemcitabine molecule and replacement of uracil bases with 5-halouracil increases the ability of the microRNA to inhibit cancer development. As such, the present disclosure provides various modified nucleic acid (e.g., microRNA) compositions having gemcitabine molecules incorporated in their nucleic acid sequences and methods for using the same. The present disclosure further provides pharmaceutical compositions comprising the modified nucleic acid compositions, and methods for treating cancers using the same. |
| FILED | Friday, March 13, 2020 |
| APPL NO | 17/439025 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/713 (20130101) A61K 31/7115 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/02 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/111 (20130101) C12N 15/1135 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145306 | Zhao et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yangbing Zhao (Lumberton, New Jersey); Jiangtao Ren (Philadelphia, Pennsylvania); Xiaojun Liu (Wallingford, Pennsylvania); Carl H. June (Merion Station, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods for generating a modified T cell with a nucleic acid capable of downregulating endogenous gene expression selected from the group consisting of TCR α chain, TCR β chain, beta-2 microglobulin and FAS further comprising a nucleic acid encoding a modified T cell receptor (TCR) comprising affinity for a surface antigen on a target cell or an electroporated nucleic acid encoding a chimeric antigen receptor (CAR). Also included are methods and pharmaceutical compositions comprising the modified T cell for adoptive therapy and treating a condition, such as an autoimmune disease. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 17/456436 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 35/26 (20130101) A61K 39/001102 (20180801) A61K 2039/5156 (20130101) A61K 2039/5158 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 37/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/85 (20130101) C12N 15/1138 (20130101) Original (OR) Class C12N 2310/10 (20130101) C12N 2310/20 (20170501) C12N 2501/48 (20130101) C12N 2501/515 (20130101) C12N 2501/599 (20130101) C12N 2501/998 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145308 | Crecy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Inc. (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Valerie Anne De Crecy (Gainesville, Florida); Geoffrey Jean Hutinet (Gainesville, Florida) |
| ABSTRACT | The present disclosure is directed to materials and methods for reducing heterologous DNA damage in bacteria (i.e., induce resistance to host restriction enzymes) by modifying the heterologous DNA to include one or more deazapurine bases. |
| FILED | Tuesday, March 10, 2020 |
| APPL NO | 17/433631 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/93 (20130101) C12N 9/1051 (20130101) C12N 15/70 (20130101) Original (OR) Class C12N 2795/00051 (20130101) Enzymes C12Y 603/0402 (20150701) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145338 | Veech et al. |
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| FUNDED BY |
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| APPLICANT(S) | Oxford University Innovation Limited (Oxford, United Kingdom); U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT (BETHESDA, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard Lewis Veech (Rockville, Maryland); Michael Todd King (Gaithersburg, Maryland); Kieran Clarke (Oxford, United Kingdom) |
| ABSTRACT | Novel compounds and compositions containing (R)-3-hydroxybutyrate derivatives are disclosed. The compounds and compositions can be used as nutritional supplements to increase physical performance and as therapeutics to ameliorate symptoms of medical conditions, particularly neurological conditions, such as Alzheimer's and similar conditions. Novel methods for making R-3-hydroxybutyrate derivatives also are disclosed. Exemplary methods employ a supercritical solvent, such as supercritical carbon dioxide, and employ a lipase catalyzed esterification or transesterification reaction to produce the (R)-3-hydroxybutyrate derivatives. |
| FILED | Monday, January 24, 2022 |
| APPL NO | 17/582744 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 51/09 (20130101) C07C 69/675 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 13/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 63/06 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/26 (20130101) C12P 7/62 (20130101) C12P 7/625 (20130101) Original (OR) Class Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/54 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145343 | CHEN et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xi CHEN (Davis, California); Riyao LI (Davis, California); Hai YU (Woodland, California) |
| ABSTRACT | Methods for preparing saccharide products such as bacterial capsular polysaccharides are provided. The methods include: forming a reaction mixture containing one or more bacterial capsular polysaccharide synthases, a sugar acceptor, and one or more sugar donors; and maintaining the reaction mixture under conditions sufficient to form the bacterial capsular saccharide product. Vaccine compositions containing bacterial capsular saccharide products prepared according to the methods are also described. |
| FILED | Friday, February 07, 2020 |
| APPL NO | 17/429299 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/092 (20130101) A61K 39/095 (20130101) A61K 39/102 (20130101) A61K 39/0258 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/04 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145363 | CAMPBELL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | MESO SCALE TECHNOLOGIES, LLC. (Rockville, Maryland); The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. (Bethesda, Maryland); The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher CAMPBELL (Columbia, Maryland); Kimbra KENNEY (Bethesda, Maryland); Jessica GILL (Reston, Virginia) |
| ABSTRACT | The invention relates to methods and kits for assessing brain injury, e.g., traumatic brain injury resulting from blast exposure. The invention provides methods of quantifying the amount of phosphorylated tau or total tau in a biological sample. The invention further provides a method of determining the number of blast exposures experienced by a subject. Also provided herein are kits for detecting phosphorylated tau or total tau in a biological sample. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/453991 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6853 (20130101) C12Q 2600/112 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/76 (20130101) G01N 27/327 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145365 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | George M. Church (Brookline, Massachusetts); Jehyuk Lee (Allston, Massachusetts); Daniel Levner (Boston, Massachusetts); Michael Super (Lexington, Massachusetts) |
| ABSTRACT | Methods of analyzing nucleic acids of a cell are provided. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 17/584959 |
| CURRENT CPC | Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Original (OR) Class C12Q 1/6844 (20130101) C12Q 1/6869 (20130101) C12Q 1/6874 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145375 | Bowers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (Phoenix, Arizona); ARIZONA BOARD OF REGENTS ON BEHALF OF NORTHERN ARIZONA UNIVERSITY (Flagstaff, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jolene Bowers (Flagstaff, Arizona); Elizabeth Driebe (Flagstaff, Arizona); David Engelthaler (Flagstaff, Arizona); Paul Keim (Flagstaff, Arizona); Darrin Lemmer (Flagstaff, Arizona) |
| ABSTRACT | The present invention provides a method of detecting one or more Klebsiella species within a sample from a subject, the method comprising: subjecting DNA and/or RNA from the sample to a PCR amplification reaction using primer pairs targeting species-specific canonical single nucleotide polymorphisms (canSNPs); and analyzing amplification products resulting from the PCR amplification reaction to detect the one or more Klebsiella species. The present invention also provides a kit for detection of one or more Klebsiella species, Klebsiella clonal groups, AMR genes, and/or virulence genes, the kit comprising primer pairs targeting species-specific canSNPs, K. pneumoniae genes M1 and M2, clonal group-specific canSNPs, AMR genes, and/or virulence genes. |
| FILED | Friday, January 28, 2022 |
| APPL NO | 17/588196 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) C12Q 1/689 (20130101) Original (OR) Class C12Q 1/6827 (20130101) C12Q 1/6853 (20130101) C12Q 2600/16 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145380 | DOAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Ryan N. DOAN (Boston, Massachusetts); Christopher A. WALSH (Boston, Massachusetts) |
| ABSTRACT | Methods are described for the detection of low frequency genetic variants, such as somatic mosaic variants. The methods comprise parallel amplification reactions of a target nucleic acid sequence to generate overlapping amplicons, pooled sequencing of the amplicons, and demultiplexed detection of low frequency variants. |
| FILED | Tuesday, November 26, 2019 |
| APPL NO | 17/427394 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6851 (20130101) Original (OR) Class C12Q 1/6886 (20130101) C12Q 2600/118 (20130101) C12Q 2600/156 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145387 | Fraser et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Scott E. Fraser (Glendale, California); Simon Restrepo (Culver City, California); Joseph P. Dunham (Glendale, California) |
| ABSTRACT | Described herein is a method to create dendritic biocompatible polymers from pairs of complementary dendritic nucleic acid monomers in a controlled manner, using polymerization triggers. The dendritic monomers are constituted of nucleic acids and an organic polymer capable of self-assembly. A variety of additional improvements are described herein, including processes not requiring snap cooling, “wobble clamp” designs to confer a transitory measure of hairpin stability prior to branch migration, and multiple assemblies of amplifying systems. Depending on the context this technology could be used to reveal the presence of a large variety of analytes such as specific nucleic acid molecules, small molecules, proteins, and peptides. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 17/415586 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6841 (20130101) C12Q 1/6855 (20130101) C12Q 1/6876 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145393 | Jeffries |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oklahoma Medical Research Foundation (Oklahoma City, Oklahoma); The Board of Regents of the University of Oklahoma (Norman, Oklahoma) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Matlock Jeffries (Oklahoma City, Oklahoma) |
| ABSTRACT | The present invention includes a method for determining whether a subject diagnosed with osteoarthritis is at increased risk for progression to severe osteoarthritis within 12-24 months, the method comprising the steps of: (a) preparing a blood sample; (b) measuring in the blood sample prepared in step (a) a level of DNA methylation; (c) comparing the DNA methylation level(s) measured in step (b) to a control blood sample level(s) of DNA methylation, and (d) identifying the subject as being at increased risk for progression to severe osteoarthritis within 12-24 months when the DNA methylation is increased by at least 2 fold as compared to the control blood level(s) of DNA methylation. |
| FILED | Tuesday, November 02, 2021 |
| APPL NO | 17/517431 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145394 | Meyer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Indiana University Research and Technology Corporation (Indianapolis, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jason S. Meyer (Indianapolis, Indiana); Kirstin Brooke VanderWall (Indianapolis, Indiana) |
| ABSTRACT | In certain aspects, the present disclosure provides methods and materials for detection and characterization of retinal ganglion cells in a sample. In accordance with certain embodiments, the present disclosure provides systems and methods for detection of disease or diseased states related to retinal ganglion cells. In some forms the disclosure provides for a method for diagnosing a disease or diseased state related to retinal ganglion cells in a patient, the method comprising the step of detecting in a body fluid of the patient one or more markers associated with the disease or diseased state. |
| FILED | Wednesday, November 24, 2021 |
| APPL NO | 17/534878 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0619 (20130101) C12N 2506/03 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/158 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146498 | Vanapalli et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Siva A. Vanapalli (Lubbock, Texas); Taslim Anupom (Lubbock, Texas); Mizanur Rahman (Lubbock, Texas); Siddhartha Gupta (Lubbock, Texas) |
| ABSTRACT | The present invention includes a system and method for analyzing animals including: a media reservoir and a media pump in fluid communication with the media reservoir; a food reservoir and a food pump in fluid communication with the food reservoir; an input port in fluid communication with the media pump and the food pump; a microfluidic device in fluid communication with the input port including: a micropillar arena or a plurality of micropillar chambers; an outlet port in fluid communication with the microfluidic device; a light source positioned outside the micropillar arena to illuminate the interior of the micropillar arena; an imager positioned outside the micropillar arena to image the interior of the micropillar arena; and a controller coupled to the media pump, the food pump, the microfluidic device, the light source, and the imager. |
| FILED | Thursday, March 05, 2020 |
| APPL NO | 17/436194 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 2200/0684 (20130101) B01L 2300/0663 (20130101) B01L 2300/0883 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5085 (20130101) Original (OR) Class G01N 2333/43534 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146500 | Johnson |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raymond Johnson (Branford, Connecticut) |
| ABSTRACT | The invention includes compositions comprising a therapeutic agent that decreases the population of pathological CD4g13 T cells, g13Th1 or g13Th2, in a subject and compositions comprising a therapeutic agent that increases the population of protective CD4g13 T cells, g13Th1 or g13Th2, in a subject. The invention also includes methods for treating an inflammatory or autoimmune disease in a subject by administering to the subject an effective amount of a therapeutic agent that increases the population of protective CD4g13 T cells, methods for detecting a protective or pathological immune response and methods for stimulating a protective CD4g13 T cell-mediated immune response to a cell population or a local tissue or organ in a subject in need thereof. The invention further includes a kit for diagnosing a pathological or protective g13Th1 or g13Th2 T cell responses in a subject. |
| FILED | Thursday, February 27, 2020 |
| APPL NO | 17/434251 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/112 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/564 (20130101) G01N 33/5091 (20130101) Original (OR) Class G01N 33/6866 (20130101) G01N 33/6869 (20130101) G01N 2333/55 (20130101) G01N 2333/57 (20130101) G01N 2333/5406 (20130101) G01N 2333/5409 (20130101) G01N 2333/5437 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146507 | Kamei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Daniel Takashi Kamei (Monterey Park, California); Maie A. St. John (Los Angeles, California); Zachary D. Taylor (Los Angeles, California); Daniel William Bradbury (Los Angeles, California); Ashley Elizabeth Kita (Los Angeles, California) |
| ABSTRACT | Devices and methods are provided for the detection of CSF in a biological sample. In certain embodiments the device is a lateral flow device comprising: a porous substrate; a sample addition zone disposed on or in said porous substrate; a detection zone disposed on or in said porous substrate where said detection zone comprises at least a first test line (T1) and a second test line (T2) each test line comprising binding moieties that bind a complex formed between beta-trace protein (βTP) and an indicator attached to a βTP binding molecule; wherein said porous substrate defines a flow path through which a sample applied to the sample addition zone flows under capillary action away from said sample addition zone into said detection zone; and wherein said first test line (T1) and said second test line (T2) are is configured so that either no test line signal or just a signal at the first test line (T1) is detectable when βTP concentration in a sample applied to said device is lower than the βTP level indicative of a CSF leak; and said second test line (T2) is configured so that a signal is detectable at said second test line when βTP concentration in a sample applied to said device is greater than the βTP level indicative of a CSF leak. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 17/530336 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) B01L 2400/0406 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54386 (20130101) Original (OR) Class G01N 2333/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146514 | Campbell et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Becton, Dickinson and Company (Franklin Lakes, New Jersey) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Campbell (Bullock, North Carolina); Kevin G. Dolan (Holly Springs, North Carolina); Eric Fallows (Apex, North Carolina); Randal A. Hoke (Cary, North Carolina); Ross Jacobson (Hillsborough, North Carolina); J. Bruce Pitner (Durham, North Carolina); Glenn P. Vonk (Fuquay Varina, North Carolina); Rajashaker Kache (Cary, North Carolina); Upma Gulati (Cary, North Carolina); Herman D. Himel, IV (Cary, North Carolina); Rosemary B. Evans-Storms (Durham, North Carolina) |
| ABSTRACT | Some embodiments provided herein relate to combined assays. In some embodiments, an assay for identifying influenza type A or influenza type B is combined with an assay for determining the sensitivity of an influenza neuraminidase to an antiviral drug. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/527524 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/54388 (20210801) G01N 33/56983 (20130101) Original (OR) Class G01N 2333/11 (20130101) G01N 2333/924 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146523 | ZHENG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jie ZHENG (Plano, Texas); Mengxiao YU (Frisco, Texas); Xuhui NING (Richardson, Texas) |
| ABSTRACT | A method for evaluating kidney function utilizing a nanoparticle that can be eliminated from the body by the kidneys as an exogenous marker. The method includes administering the nanoparticles to a subject, followed by collecting a blood or urine sample after a period of time, characterizing the nanoparticles in the blood or urine sample, and finally comparing a characteristic parameter of the nanoparticles in the blood or urine sample between the tested subject and a control group having normal kidney function. |
| FILED | Wednesday, February 26, 2020 |
| APPL NO | 17/434132 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/0004 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/587 (20130101) Original (OR) Class G01N 2800/347 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146532 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky); New York University (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Qingjun Wang (Lexington, Kentucky); Beatrix M. Ueberheide (New York, New York) |
| ABSTRACT | A compound and a method of detecting CLN3 are provided. The compound includes a heavy isotope labeled CLN3 proteotypic peptide. The method includes i) selecting a CLN3 proteotypic peptide that exhibits linear behavior in the mass spectrometer; ii) generating a stable isotope labeled standard; iii) spiking known amounts of the stable isotope labeled standard into a sample to form a spiked sample; iv) determining retention times and establishing calibration curves using the spiked sample; and v) detecting unlabeled selected CLN3 proteins in the sample. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/521788 |
| CURRENT CPC | General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/7233 (20130101) G01N 33/58 (20130101) G01N 33/6893 (20130101) Original (OR) Class G01N 2458/15 (20130101) G01N 2496/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146749 | Bandyopadhyay et al. |
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| FUNDED BY |
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| APPLICANT(S) | Saumil Bandyopadhyay (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Saumil Bandyopadhyay (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ABSTRACT | The next-generation of optoelectronic systems will require efficient optical signal transfer between many discrete photonic components integrated onto a single substrate. While modern assembly processes can easily integrate thousands of electrical components onto a single board, photonic assembly is far more challenging due to the wavelength-scale alignment tolerances required. Here we address this problem by introducing a self-aligning photonic coupler insensitive to x, y, z displacement and angular misalignment. The self-aligning coupler provides a translationally invariant evanescent interaction between waveguides by intersecting them at an angle, which enables a lateral and angular alignment tolerance fundamentally larger than non-evanescent approaches such as edge coupling. This technology can function as a universal photonic connector interfacing photonic integrated circuits and microchiplets across different platforms. For example, it can be used in a self-aligning photonic circuit board that can be assembled more easily, with larger misalignment tolerances, than other complex optoelectronic systems. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470803 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) Original (OR) Class G02B 2006/12147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148252 | Puett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The University of North Carolina at Chapel Hill (Chapel Hill, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Connor Puett (Durham, North Carolina); Otto Z. Zhou (Chapel Hill, North Carolina); Jianping Lu (Chapel Hill, North Carolina); Christina Inscoe (Holly Springs, North Carolina) |
| ABSTRACT | Systems and methods for generating multi-view synthetic dental radiographs for intraoral tomosynthesis. In some embodiments, the method includes generating or receiving two-dimensional (2D) projection images, manipulating pixel values contained in each of the plurality of 2D projection images, reconstructing a three-dimensional (3D) image space from information available in the plurality of 2D projection images, the 3D image space comprising voxel values, manipulating the voxel values in the 3D image space using one or more tunable weighting algorithms that can be adjusted to emphasize one or more features of interest of each image in the 3D image space, generating a plurality of synthetic dental radiographs from multiple views using information available in the 3D image space, and displaying one or more of the synthetic dental radiographs. In some embodiments, the system includes a display in communication with an image processing system comprising one or more processors for performing the method. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 17/529346 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 6/14 (20130101) A61B 6/025 (20130101) Image Data Processing or Generation, in General G06T 5/002 (20130101) G06T 11/006 (20130101) G06T 15/08 (20130101) Original (OR) Class G06T 15/20 (20130101) G06T 2207/10116 (20130101) G06T 2207/20081 (20130101) G06T 2207/30036 (20130101) G06T 2210/41 (20130101) G06T 2211/424 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148708 | NARAYANAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Shrikanth Sambasivan NARAYANAN (Santa Monica, California); Gayla MARGOLIN (Los Angeles, California); Adela C. AHLE (San Francisco, California); Theodora CHASPARI (College Station, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (LOS ANGELES, California) |
| INVENTOR(S) | Shrikanth Sambasivan NARAYANAN (Santa Monica, California); Gayla MARGOLIN (Los Angeles, California); Adela C. AHLE (San Francisco, California); Theodora CHASPARI (College Station, Texas) |
| ABSTRACT | A method for monitoring and understanding interpersonal relationships includes a step of monitoring interpersonal relations of a couple or group of interpersonally connected users with a plurality of smart devices by collecting data streams from the smart devices. Representations of interpersonal relationships are formed for increasing knowledge about relationship functioning and detecting interpersonally-relevant mood states and events. Feedback and/or goals are provided to one or more users to increase awareness about relationship functioning. |
| FILED | Monday, December 27, 2021 |
| APPL NO | 17/562647 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) A61B 5/4803 (20130101) A61B 5/6801 (20130101) A61B 5/6898 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/70 (20180101) Original (OR) Class G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148710 | Buckland et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Translational Imaging Innovations, Inc. (Hickory, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Eric L. Buckland (Hickory, North Carolina); Joseph Carroll (New Berlin, Wisconsin); Robert C. Williams (Durham, North Carolina); Andrew J. Witchger, JR. (Durham, North Carolina) |
| ABSTRACT | Integrated systems for collecting, storing, and distribution of images acquired of subjects in a research or clinical environment are provided. The system includes an image and data repository including a plurality of images originating from one or more image-generating devices, data associated with the images, and data associated with imaged subjects; and a workflow management module in direct communication with the image and data repository and with the one or more image-generating devices and/or storage devices that store the images of the imaged subjects, the workflow management module being configured to transport the images directly from the one or more image-generating devices and/or storage devices to the image and data repository and to manage the collation and distribution of images, data associated with the raw images and the data associated with the imaged subjects in the image and data repository. The workflow management module includes a data integration module, a data management module, a pre-processing engine and a data utilization module. |
| FILED | Friday, April 03, 2020 |
| APPL NO | 16/839475 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/542 (20130101) G06F 11/3476 (20130101) G06F 21/6218 (20130101) G06F 2221/2141 (20130101) Image Data Processing or Generation, in General G06T 7/20 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148731 | Hawkins-Daarud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrea J. Hawkins-Daarud (Houston, Texas); Leland S. Hu (Phoenix, Arizona); Kristin R. Swanson (Phoenix, Arizona); Teresa Wu (Gilbert, Arizona); Jing Li (Marietta, Georgia); Lujia Wang (Scottsdale, Arizona) |
| ABSTRACT | Genetic and/or other biological marker prediction data are generated based on inputting medical image data to a suitably trained machine learning model, where the output genetic prediction data not only indicate a prediction of genetic features and/or other biological markers for a subject, but also a measure of uncertainty in each of those predictions. As an example, a transductive learning Gaussian process model is used to generate the genetic and/or other biological marker predication data and corresponding predictive uncertainty data. As another example, a knowledge-infused global-local data fusion model can be used for spatial predictive modeling. |
| FILED | Thursday, November 11, 2021 |
| APPL NO | 17/524591 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0263 (20130101) A61B 5/7267 (20130101) A61B 2576/026 (20130101) Computer Systems Based on Specific Computational Models G06N 5/022 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/20 (20190201) G16B 40/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20220142566 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Hen-Wei Huang (Cambridge, Massachusetts); James Byrne (Boston, Massachusetts); Carlo Giovanni Traverso (Newton, Massachusetts) |
| ABSTRACT | Articles, systems, and methods for rapid administration and active pharmaceutical compositions to subjects exposed to radiation and/or toxins are provided by this disclosure. There are currently few interventional technologies to protect against long-term morbidity and mortality from exposure to radiation and chemical warfare. Furthermore, as commercially available technologies such as additive manufacturing and small-scale chemical reactors have become more prevalent, the risk of misuse of such technologies by terrorists and rogue nation states to manufacture nuclear, radiologic, and chemical weapons continues to increase. Articles, systems, and methods described herein combine sensing technologies with drug release components, in order to provide an approach for rapid diagnosis of and response to exposure to radiation and toxic agents. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470942 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1473 (20130101) A61B 5/4839 (20130101) Original (OR) Class A61B 5/4845 (20130101) A61B 5/6861 (20130101) A61B 6/425 (20130101) A61B 6/4258 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/4748 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 5/158 (20130101) A61M 31/00 (20130101) A61M 2205/21 (20130101) A61M 2205/3303 (20130101) A61M 2210/1053 (20130101) A61M 2230/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143053 | Muratoglu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Orhun K. Muratoglu (Cambridge, Massachusetts); Ebru Oral (Newton, Massachusetts); Dmitry Gil (Quincy, Massachusetts) |
| ABSTRACT | The present invention provides methods for making and using antibacterial polymeric materials loaded with additives, as well as antibacterial materials comprising additives. Certain additives or combinations of additives show unexpected combinatorial or synergistic antibacterial activity. The invention also provides medical devices comprised of antibacterial polymeric materials, and methods of making and using such devices, which can have unexpected combinatorial or synergistic antibacterial activity. |
| FILED | Tuesday, March 24, 2020 |
| APPL NO | 17/437912 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/065 (20130101) A61K 31/121 (20130101) A61K 31/167 (20130101) A61K 31/196 (20130101) A61K 31/245 (20130101) A61K 31/407 (20130101) A61K 31/445 (20130101) A61K 31/702 (20130101) Original (OR) Class A61K 38/14 (20130101) A61K 47/32 (20130101) Indexing Scheme Associated With Subclasses B29B, B29C or B29D, Relating to Moulding Materials or to Materials for Reinforcements, Fillers or Preformed Parts, e.g Inserts B29K 2023/0683 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143093 | BHATNAGAR et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Parijat BHATNAGAR (Belmont, California); Marvin A. SSEMADAALI (Menlo Park, California) |
| ABSTRACT | An example genetically engineered effector cell comprises an exogenous polynucleotide sequence that includes a receptor element, an actuator element, and an effector element. The receptor element encodes a chimeric antigen receptor (CAR) comprising an extracellular antigen binding domain operably linked to a transmembrane domain, and an intracellular signaling domain, wherein the extracellular antigen binding domain recognizes an antigen on a surface of a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-infected cell. The actuator element encodes a transcription factor binding site that upregulates synthesis of an antiviral protein. The effector element encodes the antiviral protein operably linked to a signal peptide, wherein, in response to the antigen binding domain of the CAR binding to the antigen of SARS-CoV-2-infected cell, the engineered effector cell is configured to activate and, to synthesize and secrete the antiviral protein. |
| FILED | Thursday, January 27, 2022 |
| APPL NO | 17/586749 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) Peptides C07K 14/7051 (20130101) C07K 16/2803 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143169 | RICHARDSON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Takeda Vaccines, Inc. (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Charles RICHARDSON (Cambridge, Massachusetts); Thomas S. VEDVICK (Cambridge, Massachusetts); Thomas R. FOUBERT (Cambridge, Massachusetts); William TINO (Cambridge, Massachusetts) |
| ABSTRACT | The present invention relates to vaccine compositions comprising Norovirus antigens and adjuvants, in particular, mixtures of monovalent VLPs and mixtures of multivalent VLPs, and to methods of conferring protective immunity to Norovirus infections in a human subject. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 17/348045 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/5258 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143171 | Tang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MicroVAX, LLC (Warrenton, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yucheng Tang (San Diego, California); Albert B. Deisseroth (Potomac, Maryland) |
| ABSTRACT | Provided are methods of generating an immune response to any of various antigens including foreign antigens such as infectious agent antigens. In general, the method comprises administering an expression vector encoding a transcription unit encoding a secretable fusion protein, the fusion protein containing the foreign antigen and CD40 ligand and also administering the encoded fusion protein. In another approach, an immune response to the foreign antigen is elicited using the encoded fusion protein without administering the vector. The invention methods may be used to immunize an individual against an infectious agent such as influenza virus. Methods of obtaining an immune response in older individuals also is described. |
| FILED | Monday, August 02, 2021 |
| APPL NO | 17/391103 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/145 (20130101) Original (OR) Class A61K 2039/575 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143219 | BORDEY et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | YALE UNIVERSITY (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Angelique BORDEY (Guilford, Connecticut); Lawrence HSIEHI (West Hartford, Connecticut); Jianbing ZHOU (New Haven, Connecticut) |
| ABSTRACT | In various aspects and embodiments the invention provides a method of treating epilepsy in a subject in need thereof the method comprising contacting a target cell of the subject with an effective amount of an HCN4 disrupting agent. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 17/436165 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/005 (20130101) A61K 48/0016 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 15/1138 (20130101) C12N 2310/20 (20170501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143551 | Sibener et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven J. Sibener (Chicago, Illinois); Kevin D. Gibson (Blue Island, Illinois) |
| ABSTRACT | Methods for enriching, separating, or enriching and separating isotopes and isotopologues, as well as other chemical species, contained in a supersonic beam are provided. In the methods, a supersonic beam having different isotopes, isotopologues, or other chemical species entrained therein and a beam comprising a matrix material converge on a surface. As the matrix material forms a solid matrix on the surface, heavier isotopes, isotopologues, and/or other chemical species become preferentially embedded in the matrix, while lighter isotopes, isotopologues, and/or other chemical species are preferentially scattered from the surface. |
| FILED | Wednesday, November 03, 2021 |
| APPL NO | 17/453357 |
| CURRENT CPC | Separation B01D 59/34 (20130101) Original (OR) Class Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 1/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143748 | Reicks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew R. Reicks (Lincoln, Nebraska); Craig Zuhlke (Lincoln, Nebraska); Alfred Tooru Tsubaki (Lincoln, Nebraska); Christos Argyropoulos (Lincoln, Nebraska); George Gogos (Lincoln, Nebraska); Mark Anderson (Lincoln, Nebraska); Dennis R. Alexander (Lincoln, Nebraska) |
| ABSTRACT | A method for laser-processing a metallic surface to produce a functionalized metallic surface comprises: providing a substrate having the metallic surface; applying a pulsed laser beam with a controlled fluence to a region of the metallic surface in an environment containing oxygen, wherein metal material in the region of the metallic surface ablates due to the applied pulsed laser beam and wherein at least a portion of the ablated metal material oxidizes and redeposits on the metallic surface to produce one or more oxidized-metal-coated structures; wherein the metallic surface having the one or more oxidized-metal-coated structures is the functionalized metallic surface. Optionally, the functionalized metallic surface has a higher hemispherical emissivity than the metallic surface free of the oxidized-metal-coated structures and prior to applying the pulsed laser beam under otherwise identical conditions. Optionally, the functionalized metallic surface is characterized by a hemispherical emissivity of at least 0.85. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/525094 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/123 (20130101) B23K 26/352 (20151001) B23K 26/0624 (20151001) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143828 | Blankespoor et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| ASSIGNEE(S) | Boston Dynamics, Inc. (Waltham, Massachusetts) |
| INVENTOR(S) | Kevin Blankespoor (Arlington, Massachusetts); Alex Perkins (Arlington, Massachusetts); Marco da Silva (Waltham, Massachusetts) |
| ABSTRACT | An example method may include i) determining a first distance between a pair of feet of a robot at a first time, where the pair of feet is in contact with a ground surface; ii) determining a second distance between the pair of feet of the robot at a second time, where the pair of feet remains in contact with the ground surface from the first time to the second time; iii) comparing a difference between the determined first and second distances to a threshold difference; iv) determining that the difference between determined first and second distances exceeds the threshold difference; and v) based on the determination that the difference between the determined first and second distances exceeds the threshold difference, causing the robot to react. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 17/581361 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/1633 (20130101) B25J 9/1653 (20130101) Original (OR) Class B25J 13/085 (20130101) Motor Vehicles; Trailers B62D 57/032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144357 | PANTALEO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CARNEGIE MELLON UNIVERSITY (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Richard PANTALEO (Pittsburgh, Pennsylvania); Dimitrios APOSTOLOPOULOS (Pittsburgh, Pennsylvania); Edward MUTSCHLER (Pittsburgh, Pennsylvania); Matthew GLISSON (Pittsburgh, Pennsylvania) |
| ABSTRACT | The Reconfigurable Wheel-Track (RWT) device is a novel mechanism that allows a wheel to transform into a track, and vice versa. The wheel mode allows a vehicle to travel quickly over smooth and semi-rough terrain, then, on-the-fly, transform rapidly into a powered track mode for crossing extreme terrain. The reconfigurable wheeltrack device comprises several main components: an outer tire/tread, a drive mechanism for driving the tread when in track mode and a reconfiguration mechanism that facilitates the transformation from wheel mode to track mode and vice versa. The reconfigurable wheel-track includes sensing, actuation, and controls to facilitate efficient and effective transitions, and securely maintain each wheel and track shape. |
| FILED | Wednesday, April 29, 2020 |
| APPL NO | 17/433802 |
| CURRENT CPC | Vehicle Wheels; Castors; Axles for Wheels or Castors; Increasing Wheel Adhesion B60B 19/12 (20130101) Motor Vehicles; Trailers B62D 55/04 (20130101) B62D 55/10 (20130101) Original (OR) Class B62D 55/12 (20130101) B62D 55/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144418 | Kennedy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Boeing Company (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dennis K. Kennedy (Mesa, Arizona); Joshua Jeffrey Bracken (Gilbert, Arizona); Jeffrey L. Sorensen (Fountain Hills, Arizona) |
| ABSTRACT | A rotor assembly comprises a rotor hub and rotor-blade assemblies. The rotor hub comprises rotor-blade supports. Each rotor-blade assembly is coupled to a respective one of the rotor-blade supports and comprises a flap axle, a hub connector, a rotor blade, and a torsion strap. The flap axle extends through a respective one of the rotor-blade supports and has a central flap-axle axis. The hub connector is pivotable relative to a rotor-blade support about the central flap-axle axis and defines a central hub-connector axis. The rotor blade is coupled to and is pivotable relative to the hub connector, and, together with the hub connector, is pivotable relative to a respective one of the rotor-blade supports about the central flap-axle axis. The torsion strap has a first end, coupled to the rotor blade, and a second end, through which the flap axle passes. |
| FILED | Thursday, May 20, 2021 |
| APPL NO | 17/326222 |
| CURRENT CPC | Aeroplanes; Helicopters B64C 27/35 (20130101) B64C 27/39 (20130101) Original (OR) Class B64C 27/48 (20130101) B64C 27/78 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144636 | Alston et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey R. Alston (High Point, North Carolina); Jason T. Lamb (Huntersville, North Carolina) |
| ABSTRACT | A method for purifying a boron nitride nanotube feedstock is disclosed, including an initial step of mixing a boron nitride nanotube (BNNT) feedstock with a solvent to form an initial mixture. This BNNT feedstock is made up of hexagonal boron nitride (h-BN) particles and less than about 50 weight percent BNNTs on a dry basis. This initial mixture is then sonicated within a treatment vessel using an ultrasonic probe. At least a portion of the initial mixture is filtered out of the treatment vessel and across a nanoporous membrane at the same as the sonication. In this manner, the method provides a filtrate which is enriched in h-BN particles relative to the initial mixture and a retentate which is enriched in BNNTs relative to the initial mixture. |
| FILED | Thursday, January 20, 2022 |
| APPL NO | 17/579633 |
| CURRENT CPC | Separation B01D 11/0265 (20130101) B01D 71/36 (20130101) B01D 2325/02 (20130101) Non-metallic Elements; Compounds Thereof; C01B 21/0648 (20130101) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2004/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144702 | Srubar, III et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| ASSIGNEE(S) | The Regents of the University of Colorado, a body corporate (Denver, Colorado) |
| INVENTOR(S) | Will V. Srubar, III (Boulder, Colorado); Sherrie Cook (Boulder, Colorado); Mija Hubler (Boulder, Colorado); Jeffrey Cameron (Erie, Colorado) |
| ABSTRACT | Disclosed are biopolymeric and biologically active mortars suitable for use in providing building materials having enhanced physical properties. Further disclosed are methods for making and using the disclosed materials. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 17/436581 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 14/06 (20130101) C04B 24/00 (20130101) Original (OR) Class C04B 2103/0001 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144970 | CAVACINI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Massachusetts (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lisa CAVACINI (Boston, Massachusetts); Mark S.J. KLEMPNER (Boston, Massachusetts) |
| ABSTRACT | The invention provides anti-polymeric IgA (plgA) antibodies and methods of using the same. |
| FILED | Friday, March 27, 2020 |
| APPL NO | 17/598385 |
| CURRENT CPC | Peptides C07K 16/4241 (20130101) Original (OR) Class C07K 2317/24 (20130101) C07K 2317/33 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145266 | INGBER et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Donald E. INGBER (Boston, Massachusetts); Magdalena KASENDRA (Boston, Massachusetts); Alexandra SONTHEIMER-PHELPS (Cambridge, Massachusetts); Alessio TOVAGLIERI (Somerville, Massachusetts) |
| ABSTRACT | Described herein are methods for providing an in vitro intestinal model system, e.g., using primary cells instead of cell lines and/or cancerous cells. |
| FILED | Wednesday, December 01, 2021 |
| APPL NO | 17/539452 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0062 (20130101) C12N 5/0068 (20130101) C12N 5/0679 (20130101) C12N 5/0697 (20130101) Original (OR) Class C12N 2501/11 (20130101) C12N 2501/345 (20130101) C12N 2501/415 (20130101) C12N 2502/1323 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5088 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145297 | Buchman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anna Buchman (La Jolla, California); Omar Akbari (La Jolla, California) |
| ABSTRACT | Provided herein are compositions and methods for CRISPR based RNA-targeting. The compositions include nucleic acid molecules comprising a sequence encoding a Cas13 polypeptide and a sequence encoding a guide RNA comprising one or more spacers and one or more Cas13-specific direct repeats, where the spacers are capable of specifically hybridizing with one or more target RNAs. The disclosure further provides methods of modifying a target RNA in a cell and transgenic organisms. |
| FILED | Wednesday, January 29, 2020 |
| APPL NO | 17/426467 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/111 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/51 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145322 | Perkins et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CarryGenes Bioengineering (Savannah, Georgia) |
| ASSIGNEE(S) | CarryGenes Bioengineering (Savannah, Georgia) |
| INVENTOR(S) | Edward Perkins (Savannah, Georgia); Amy Greene (Savannah, Georgia); Dominique Broccoli (Savannah, Georgia) |
| ABSTRACT | The present invention encompasses compositions and methods to rejuvenate cells by, expanding the replicative life span of the cells for, e.g., use in regenerative therapies. Specifically, the methods and compositions of the present invention increase the proliferation capacity and differentiation capacity and plasticity of cells. |
| FILED | Monday, January 24, 2022 |
| APPL NO | 17/582609 |
| CURRENT CPC | Peptides C07K 14/4702 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/80 (20130101) C12N 9/1276 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 2830/003 (20130101) Enzymes C12Y 207/07049 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145363 | CAMPBELL et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | MESO SCALE TECHNOLOGIES, LLC. (Rockville, Maryland); The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. (Bethesda, Maryland); The United States of America,as represented by the Secretary,Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher CAMPBELL (Columbia, Maryland); Kimbra KENNEY (Bethesda, Maryland); Jessica GILL (Reston, Virginia) |
| ABSTRACT | The invention relates to methods and kits for assessing brain injury, e.g., traumatic brain injury resulting from blast exposure. The invention provides methods of quantifying the amount of phosphorylated tau or total tau in a biological sample. The invention further provides a method of determining the number of blast exposures experienced by a subject. Also provided herein are kits for detecting phosphorylated tau or total tau in a biological sample. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/453991 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) Original (OR) Class C12Q 1/6853 (20130101) C12Q 2600/112 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/76 (20130101) G01N 27/327 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145372 | Ackerman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Anne Lenore Ackerman (Los Angeles, California); David M. Underhill (Tarzana, California) |
| ABSTRACT | The invention describes methods for a method of detecting levels of one or more microorganisms, selecting treatment for interstitial cystitis, pelvic pain, bladder pain and myofascial pain and treating interstitial cystitis, pelvic pain, bladder pain and myofascial pain. The invention also describes detecting bacterial phenotype and kits. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/525112 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/689 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145928 | Tolley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael T. Tolley (La Jolla, California); Jessica Sandoval (San Diego, California); Dimitri DEHEYN (Cardiff-by-the-Sea, California) |
| ABSTRACT | A bioinspired suction device includes a radially symmetrical suction chamber formed from a first elastomer and having a skirt portion with a skirt diameter and a disc margin formed from a flexible flattened ring adhered to a lower surface of the skirt portion. The disc margin is formed from a second elastomer and has a disc diameter that extends beyond the skirt diameter. The second elastomer is a compliant material having a lower hardness and lower tensile strength than the first elastomer. Radial pads may extend from the disc margin, where each pad has elastomeric texture features formed on a pad contact surface. |
| FILED | Wednesday, September 29, 2021 |
| APPL NO | 17/489578 |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 15/0683 (20130101) Devices for Fastening or Securing Constructional Elements or Machine Parts Together, e.g Nails, Bolts, Circlips, Clamps, Clips, Wedges, Joints or Jointing F16B 47/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146443 | BRAUN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| ASSIGNEE(S) | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (Charlottesville, Virginia) |
| INVENTOR(S) | Jeffrey L. BRAUN (Charlottesville, Virginia); David H. OLSON (Charlottesville, Virginia); John T. GASKINS (Charlottesville, Virginia); Patrick E. HOPKINS (Charlottesville, Virginia) |
| ABSTRACT | A method of measuring thermal conductivity of a material includes focusing a modulated pump laser beam having a modulation frequency that induces a cyclical steady-state temperature rise at a spot of a material, focusing a CW probe laser beam at the spot and generating a reflected probe beam reflected from the spot on the material, the reflected probe beam having a magnitude of a reflectance signal as a function of the temperature of the material and being periodic corresponding to the cyclical temperature rise, measuring the magnitude of the reflectance signals of the reflected probe beam, and determining the thermal conductivity by fitting the power of the pump beam and the measured magnitude of the reflectance signal to a thermal model which is a function of a thermal conductivity of the material relating the radial heat flux to the temperature rise. |
| FILED | Wednesday, August 28, 2019 |
| APPL NO | 17/272011 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/55 (20130101) G01N 21/1717 (20130101) G01N 25/18 (20130101) Original (OR) Class G01N 25/20 (20130101) G01N 2021/1731 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146687 | Zarowski et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayflower Communications Company, inc (Bedford, Massachusetts) |
| ASSIGNEE(S) | Mayflower Communications Company, Inc (Bedford, Massachusetts) |
| INVENTOR(S) | Christopher Jonathan Zarowski (Burlington, Massachusetts); Huan-Wan Tseng (Westford, Massachusetts); William LeComte (Burlington, Massachusetts) |
| ABSTRACT | System and method for concurrent STAP (space-time adaptive processing) filtering of interference signals (e.g., jamming signals) from signals received at a broadband antenna array via satellite and terrestrial broadcasts and communication systems operating in the 950 MHz to 1.65 GHz L-band, including but not limited to Link 16 terrestrial communications, Iridium satellite communications, and the Global Positioning System (GPS) and other Global Navigation Satellite Systems (GNSS). While the GPS/GNSS signals are protected against jamming using Nulling of the interfering signals, the Iridium and other communication systems' signals are protected using Beamforming. Use of a common broadband antenna and common front-end signal processing of the received signals enables an integrated system for use on a wide range of platforms, including without limitation size-, weight-, and power-constrained platforms such as drones, unmanned aerial vehicles (UAVs), and helicopters. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 17/581269 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/20 (20130101) G01S 19/21 (20130101) Original (OR) Class G01S 19/22 (20130101) G01S 19/23 (20130101) G01S 19/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146727 | Kim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Young L. Kim (West Lafayette, Indiana); Yunsang Kwak (Gyeongsangbuk-do, South Korea); Jungwoo Leem (West Lafayette, Indiana) |
| ABSTRACT | An Anderson localized hyperspectral filter array is disclosed which includes a base layer and a plurality of optical layers deposited on the base layer selected from two or more materials, each material having a refractive index that is different from the other materials of the two or more materials, wherein no consecutively deposited optical layers have the same refractive index, each of the plurality of optical layers having a thickness chosen based on a random number within a predetermined range. |
| FILED | Wednesday, November 03, 2021 |
| APPL NO | 17/518386 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/285 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146749 | Bandyopadhyay et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Saumil Bandyopadhyay (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Saumil Bandyopadhyay (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ABSTRACT | The next-generation of optoelectronic systems will require efficient optical signal transfer between many discrete photonic components integrated onto a single substrate. While modern assembly processes can easily integrate thousands of electrical components onto a single board, photonic assembly is far more challenging due to the wavelength-scale alignment tolerances required. Here we address this problem by introducing a self-aligning photonic coupler insensitive to x, y, z displacement and angular misalignment. The self-aligning coupler provides a translationally invariant evanescent interaction between waveguides by intersecting them at an angle, which enables a lateral and angular alignment tolerance fundamentally larger than non-evanescent approaches such as edge coupling. This technology can function as a universal photonic connector interfacing photonic integrated circuits and microchiplets across different platforms. For example, it can be used in a self-aligning photonic circuit board that can be assembled more easily, with larger misalignment tolerances, than other complex optoelectronic systems. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470803 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) Original (OR) Class G02B 2006/12147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148335 | LIU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| INVENTOR(S) | Xiaoming LIU (Okemos, Michigan); Ziyuan ZHANG (East Lansing, Michigan) |
| ABSTRACT | Gait, the walking pattern of individuals, is one of the important biometrics modalities. Most of the existing gait recognition methods take silhouettes or articulated body models as gait features. These methods suffer from degraded recognition performance when handling confounding variables, such as clothing, carrying and viewing angle. To remedy this issue, this disclosure proposes to explicitly disentangle appearance, canonical and pose features from RGB imagery. A long short-term memory integrates pose features over time as a dynamic gait feature while canonical features are averaged as a static gait feature. Both of them are utilized as classification features. |
| FILED | Friday, September 03, 2021 |
| APPL NO | 17/466117 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 10/82 (20220101) G06V 10/761 (20220101) G06V 10/774 (20220101) G06V 40/10 (20220101) G06V 40/25 (20220101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149154 | NEMANICK et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (, None) |
| INVENTOR(S) | Eric Joseph NEMANICK (Santa Monica, California); Yao Y. LAO (Irvine, California) |
| ABSTRACT | Interconnects may be formed to an electronic device by creating a strong bond between a wire or lead, one or more nanomaterials, and a contacting area on the electronic device. The creating of the strong bond comprises triggering low power air plasma to activate a surface of the one or more nanomaterials forcing the one or more nanomaterials to bond to the surface of the contacting area. |
| FILED | Monday, November 09, 2020 |
| APPL NO | 17/092765 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 24/45 (20130101) H01L 24/85 (20130101) H01L 29/0669 (20130101) Original (OR) Class H01L 2224/85048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149285 | Mei et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Jianguo Mei (West Lafayette, Indiana); Aristide Gumyusenge (West Lafayette, Indiana) |
| ABSTRACT | A composition for use as an electronic material. The composition contains at least one organic semiconducting material, and at least one electrically insulating polymer forming a semiconducting blend wherein the insulating polymer acts as a matrix for the organic semiconducting material resulting in an interpenetrating morphology of the polymer and the semiconductor material. The variation of charge carrier mobility with temperature in the semiconducting blend is less than 20 percent in a temperature range. A method of making a film of an electronic material. The method includes dissolving at least one organic semiconducting material and at least one insulating polymer into an organic solvent in a pre-determined ratio resulting in a semiconducting blend, depositing the blend onto a substrate to form a film comprising an interpenetrating morphology of the at least one insulating polymer and the at least one organic semiconductor material. |
| FILED | Thursday, November 18, 2021 |
| APPL NO | 17/530414 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/0007 (20130101) H01L 51/0028 (20130101) H01L 51/0035 (20130101) H01L 51/0036 (20130101) Original (OR) Class H01L 51/0042 (20130101) H01L 51/0043 (20130101) H01L 51/0545 (20130101) H01L 51/0566 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149301 | Priya et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Shashank Priya (State College, Pennsylvania); Yuchen Hou (, None); Kai Wang (Zhejiang, China PRC) |
| ABSTRACT | Embodiments relate to a light-harvesting perovskite layer including having deoxyribonucleic acid (DNA) molecules incorporated within the perovskite crystal to serve as an effective carrier transport medium. Some embodiments include formation of a DNA doped MAPbI3, the DNA doped MAPbI3 being formed by using a DNA-hexadecyl trimethyl ammonium chloride (“DNA-CTMA”) complex. The DNA doped MAPbI3 can be used as the light-harvesting perovskite layer in a photovoltaic device. Other molecules such as artemisinin (ART) and melanin are also demonstrated to show the effectiveness in charge and thermal transport. |
| FILED | Friday, May 01, 2020 |
| APPL NO | 17/594591 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0093 (20130101) Original (OR) Class H01L 51/5004 (20130101) H01L 2251/301 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149624 | LEEB et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven B. LEEB (Belmont, Massachusetts); John K. NOWOCIN (Cambridge, Massachusetts); Peter LINDAHL (Wellesley, Massachusetts); Spencer SHABSHAB (McLean, Virginia) |
| ABSTRACT | Described are systems and techniques for extracting frequency and voltage harmonic transients corresponding to individual load events. Such systems and techniques can be used to make electrical loads aware of the operation of other loads in an electric grid. Thus, awareness is achieved using information derived only from a utility voltage waveform at a load. Also described are systems and techniques for incorporating such awareness into load controllers which allows loads to autonomously meet system level objectives in addition to their individual requirements. |
| FILED | Friday, February 14, 2020 |
| APPL NO | 17/430753 |
| CURRENT CPC | Circuit Arrangements or Systems for Supplying or Distributing Electric Power; Systems for Storing Electric Energy H02J 3/24 (20130101) H02J 3/144 (20200101) Original (OR) Class H02J 2310/10 (20200101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149841 | WHITELEY |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Synopsys, Inc. (Mountain View, California) |
| ASSIGNEE(S) | Synopsys, Inc. (Mountain View, California) |
| INVENTOR(S) | Stephen Robert WHITELEY (Sunnyvale, California) |
| ABSTRACT | Disclosed herein are embodiments including electrical structures that includes a first cell, a first inductor, a first resistor, and a first shunted Josephson junction. The first inductor is connected in series with the first shunted Josephson junction at a first terminal end of the first inductor and a second terminal end of the first inductor is connected to a feed point of the first cell being powered. A first end of the first resistor having connected to ground and a second end being connected to the first shunted Josephson junction at a terminal of the first shunted Josephson junction that is not connected to the first inductor. A source of an electrical current source that is external to the first cell is connected to the first shunted junction and the first resistor at a common point. |
| FILED | Thursday, March 12, 2020 |
| APPL NO | 17/438280 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/367 (20200101) G06F 2119/06 (20200101) Pulse Technique H03K 19/0008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149902 | Chen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SYRACUSE UNIVERSITY (Syracuse, New York) |
| ASSIGNEE(S) | SYRACUSE UNIVERSITY (Syracuse, New York) |
| INVENTOR(S) | Biao Chen (Jamesville, New York); Yang Liu (San Jose, California); Janek Mroczek (Barneveld, New York) |
| ABSTRACT | A multiple-input multiple-output (MIMO) communication system that addresses three major challenges in airborne MIMO communications, namely, antenna blockage due largely to the movement and orientation of the airborne platforms, the presence of unknown interference inherent to the intended application, and the lack of channel state information (CSI) at the transmitter. The system is implemented on a Diagonal Bell-Labs Layered Space-Time (D-BLAST) MIMO architecture and includes spatial spreading to counter antenna blockage, temporal spreading to mitigate signal to interference and noise ratio degradation due to intended or unintended interference, and a simple low rate feedback scheme to enable real time adaptation in the absence of full transmitter CSI. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 17/523538 |
| CURRENT CPC | Transmission H04B 7/26 (20130101) H04B 7/0413 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220150052 | CAMBOU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of Northern Arizona University (Flagstaff, Arizona); Government of the United States of America, as represented by the Secretary of the Air Force (Rome, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bertrand F CAMBOU (Flagstaff, Arizona); Christopher Robert PHILABAUM (Flagstaff, Arizona); Donald A. TELESCA, JR. (Whitesboro, New York) |
| ABSTRACT | A computing device includes an array of addressable elements. Each addressable element is a hardware element that generates a substantially consistent response when interrogated. The device includes a processor coupled to the array of addressable elements and configured to communicate using a communication network. The processor receives a public key, and processes the public key to produce at least a set of addresses. Each address in the set of addresses identifies one or more hardware elements in the array of addressable elements. The processor generates a set of responses by interrogating the one or more hardware elements in the array of addressable elements identified by the set of addresses according to a set of reading instructions, appends the responses in the set of responses to generate a private key, receives an encrypted message and decrypts the encrypted message using the private key to generate an unencrypted message. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579426 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 9/30 (20130101) H04L 9/0819 (20130101) Original (OR) Class H04L 9/3242 (20130101) H04L 9/3278 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220150417 | Bramlett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Science Applications International Corporation (Reston, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Eric Bramlett (Gurley, Alabama); Michael Harris Rodgers (Huntsville, Alabama) |
| ABSTRACT | Search points in a search space may be projected onto images from cameras imaging different parts of the search space. Subimages, corresponding to the projected search points, may be selected and processed to determine if a target object has been detected. Based on subimages in which target objects are detected, as well as orientation data from cameras capturing images from which the subimages were selected, positions of the target objects in the search space may be determined. |
| FILED | Monday, February 03, 2020 |
| APPL NO | 16/779917 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/70 (20170101) G06T 7/174 (20170101) G06T 2207/20021 (20130101) G06T 2207/20068 (20130101) G06T 2207/30212 (20130101) G06T 2207/30232 (20130101) G06T 2207/30244 (20130101) Image or Video Recognition or Understanding G06V 20/52 (20220101) G06V 20/60 (20220101) G06V 2201/07 (20220101) Pictorial Communication, e.g Television H04N 5/247 (20130101) Original (OR) Class H04N 5/23229 (20130101) H04N 5/23299 (20180801) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20220142557 | Arnold et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KNOW BIOLOGICAL, INC. (Milton, Georgia); National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gary Stephen Arnold (Cumming, Georgia); Matthew Wallace Moorman (Albuquerque, New Mexico); Joshua Jonathan Whiting (Albuquerque, New Mexico) |
| ABSTRACT | A volatile organic compound detection device includes a collector comprising: a collector material configured to collect volatile organic compounds given off from a patient's skin; a heater comprising a heating element, the heating element configured to emit a thermal pulse to desorb the volatile organic compounds from the collector material; and a flow channel configured to receive the volatile organic compounds desorbed by the heater; and a fastener configured to secure the collector to the patient's skin. |
| FILED | Wednesday, January 05, 2022 |
| APPL NO | 17/568799 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/443 (20130101) A61B 5/4094 (20130101) Original (OR) Class A61B 5/6831 (20130101) A61B 5/6833 (20130101) A61B 10/00 (20130101) A61B 2010/0083 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 30/00 (20130101) G01N 30/20 (20130101) G01N 30/64 (20130101) G01N 30/80 (20130101) G01N 2030/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143199 | BLAKE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tim R. BLAKE (Palo Alto, California); Paul WENDER (Palo Alto, California); Robert M. WAYMOUTH (Palo Alto, California); Ronald LEVY (Palo Alto, California); Ole Audun Werner HAABETH (Palo Alto, California); Rebecca MCCLELLAN (Palo Alto, California); Adrienne SALLETS (Palo Alto, California) |
| ABSTRACT | There are provided herein, inter alia, cationic amphipathic polymers, complexes, and compositions comprising same, and methods for their use including for the delivery of therapeutic, diagnostic and imaging agents, including nucleic acids, into a cell. The complexes, compositions and methods may facilitate delivery and targeted release of the therapeutic, diagnostic and imaging agents to particular cell types and tissues. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 17/427362 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/007 (20130101) A61K 47/549 (20170801) A61K 47/593 (20170801) Original (OR) Class A61K 48/0041 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/028 (20130101) C08G 73/0293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143548 | Malhotra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Deepika Malhotra (Richland, Washington); Phillip K. Koech (Richland, Washington); David J. Heldebrant (Richland, Washington); Vassiliki-Alexandra Glezakou (Richland, Washington); Roger J. Rousseau (Richland, Washington); Manh Thuong Nguyen (Richland, Washington); Robert Perry (Richland, Washington); Jordan P. Page (Richland, Washington); David C. Cantu (Richland, Washington) |
| ABSTRACT | Disclosed herein is a method and system for CO2 removal from a gas stream using a diamine solvent having a Formula I R1(R2)N-L1-NH—R3 Formula I. With respect to Formula I, each of R1 and R2 independently is aliphatic, cycloaliphatic, or R1 and R2 together with the nitrogen to which they are attached, form a heterocyclyl ring; L1 is aliphatic, cycloaliphatic, or L1 and R1 together with the nitrogen to which they are attached form a heterocyclyl ring; and R3 is aliphatic, cycloaliphatic, cycloalkylalkyl, or alkoxyalkyl. And/or the compound may have a viscosity of less than 75 cP at a CO2-loading of 40 mol % and at a temperature of 40° C. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 17/584597 |
| CURRENT CPC | Separation B01D 53/1425 (20130101) B01D 53/1475 (20130101) B01D 53/1493 (20130101) Original (OR) Class B01D 2252/2041 (20130101) B01D 2252/20426 (20130101) B01D 2252/20431 (20130101) B01D 2252/20452 (20130101) Heterocyclic Compounds C07D 295/13 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143585 | Percival et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico); STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen Percival (Albuquerque, New Mexico); James Eujin Park (Albuquerque, New Mexico); Ivana Gonzales (Santa Fe, New Mexico); Stanley Shihyao Chou (Albuquerque, New Mexico) |
| ABSTRACT | An electrocatalyst comprises a crumpled transition metal dichalcogenide support loaded with catalytic metal nanoparticles through spontaneous reduction reactions. The support can be prepared by hydrothermal conversion of 2D nanosheets to 3D hierarchically crumpled sheets. As an example, using crumpled MoS2 as a support, highly tunable Ru loadings were obtained using the electrostatic interaction between MoS2 and RuCl3 in solution. Control over Ru loading was leveraged to produce Ru—MoS2 electrocatalysts that demonstrate different nitrogen reduction reaction activities, and which show varying resistance to electrochemical sintering and deactivation. Further, these high surface area materials can be utilized for many applications, including electrocatalysts, supercapacitors, and batteries. |
| FILED | Tuesday, November 10, 2020 |
| APPL NO | 17/094040 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 27/0515 (20130101) Original (OR) Class B01J 35/006 (20130101) B01J 35/0033 (20130101) B01J 37/08 (20130101) B01J 37/16 (20130101) Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143918 | Kim et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seokpum Kim (Oak Ridge, Tennessee); Ahmed Arabi Hassen (Oak Ridge, Tennessee); Lonnie J. Love (Oak Ridge, Tennessee); Vlastimil Kunc (Oak Ridge, Tennessee) |
| ABSTRACT | Systems and methods for generating molecular dynamic graded lattice structures that can be used as infill for additively manufactured articles. Molecular dynamically generated lattice infill is based on force balancing a node distribution instead of a circle packing. Field data can be utilized to adjust the spacing of the node distribution according to a force balance equilibrium model that accounts for the field expected to be experienced by the article being additively manufactured. The resultant non-uniform honeycomb structures from force-balancing robustly and efficiently address the connection issues with traditional non-uniform lattice structures. |
| FILED | Wednesday, December 08, 2021 |
| APPL NO | 17/545159 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/118 (20170801) B29C 64/386 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 30/00 (20141201) B33Y 50/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144660 | Theaker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of North Dakota (Grand Forks, North Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nolan Theaker (Grand Forks, North Dakota); Daniel Laudal (Grand Forks, North Dakota); Christine E. Lucky (Madison, Wisconsin) |
| ABSTRACT | A method for recovering rare earth elements (REE) from a leach solution. The method includes determining the concentration of a first plurality of contaminates in the leach solution, adding a first amount of oxalic acid to the leach solution and allowing it to react for a first period of time to form a first precipitant and a first liquor, maintaining the pH of the first liquor between 1.5 and 3 by the addition of an alkali base, removing the first precipitant, adding a second amount of oxalic acid to the first liquor and allowing it to react for a second period of time to form a second precipitant and a second liquor, maintaining the pH of the second liquor between 1.5 and 3 by the addition of the alkali base, and removing the second precipitant. |
| FILED | Thursday, November 04, 2021 |
| APPL NO | 17/519346 |
| CURRENT CPC | Compounds of the Metals Beryllium, Magnesium, Aluminium, Calcium, Strontium, Barium, Radium, Thorium, or of the Rare-earth Metals C01F 17/10 (20200101) Original (OR) Class Acyclic or Carbocyclic Compounds C07C 51/47 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 59/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144673 | Xiang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Chengxiang Xiang (San Marino, California); Harry A. Atwater (South Pasadena, California); Ibadillah A. Digdaya (Los Angeles, California) |
| ABSTRACT | Disclosed are electrochemical systems that include an electrodialyzer and a vapor-fed CO2 reduction (CO2R) cell to capture and convert CO2 from ocean water. The electrodialyzer includes a stack of bipolar membrane electrodialysis (BPMED) cells between end electrodes. The electrodialzyer incorporates monovalent cation exchange membranes (M-CEMs) that prevent the transfer of multivalent cations between adjacent cell compartments, allowing continuous recirculation of electrolytes and solutions, and thus providing a safer and more scaling-free electrodialysis system. In some embodiments, the electrodialyzer may be configured to replace the water-splitting reaction at end electrodes with one-electron, reversible redox couples in solution at the electrodes. As a result, in the entire electrodialyzer stack, there is no bond-making, bond-breaking reactions and there is no gas generation, which significantly simplifies the cell design and improves operational safety. The systems provide a unique technological pathway for CO2 capture and conversion from ocean water with only electrochemical processes. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 17/522241 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/4693 (20130101) Original (OR) Class C02F 1/46109 (20130101) C02F 2101/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144706 | Hill et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Semplastics EHC, LLC (Oviedo, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Arnold Hill (Orlando, Florida); Walter Sherwood (Ballston Lake, New York); Ryan Trammell (Lake Mary, Florida); William Easter (Chuluota, Florida) |
| ABSTRACT | A composite material, compositions, processes and methods of using coal and coal by-products composite ceramics is provided for use as a safe, non-toxic material for construction, building and architecture components. The composite material disclosed herein is formed from resin/coal aggregates that contain and prevent the release of harmful impurities that naturally occur in both coal and coal by-products while the advantages of coal-based composites are made available to the building industry. The strength, density and porosity of the composites can be tailored within a wide range to fit the final application by controlling the materials, form factor and processing parameters during fabrication. |
| FILED | Friday, November 06, 2020 |
| APPL NO | 17/091083 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 18/022 (20130101) C04B 35/532 (20130101) Original (OR) Class C04B 35/628 (20130101) C04B 35/6261 (20130101) C04B 35/62695 (20130101) C04B 35/63448 (20130101) C04B 2111/00612 (20130101) C04B 2235/422 (20130101) C04B 2235/483 (20130101) C04B 2235/604 (20130101) C04B 2235/656 (20130101) C04B 2235/5436 (20130101) C04B 2235/5445 (20130101) C04B 2235/5454 (20130101) C04B 2235/6021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145002 | Rogers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Verdox, Inc (Woburn, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Cameron Rogers (Malden, Massachusetts); Sahag Voskian (Boston, Massachusetts) |
| ABSTRACT | A quinone-containing poly(arylene) includes repeating units of formula (I), (II), (III), (IV), (V), or (VI) as defined herein. The quinone-containing poly(arylene) can be useful in composites, electrode assemblies, electrochemical cells, gas separation systems, energy storage devices, and electrochromic devices. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470632 |
| CURRENT CPC | Separation B01D 53/02 (20130101) B01D 53/326 (20130101) B01D 2253/202 (20130101) B01D 2259/40083 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/121 (20130101) Original (OR) Class C08G 2261/12 (20130101) C08G 2261/314 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145008 | Yang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Zhenzhen Yang (Knoxville, Tennessee); Ilja Popovs (Knoxville, Tennessee); Sheng Dai (Knoxville, Tennessee) |
| ABSTRACT | A polymer composition comprising a covalent triazine framework having the following structure: wherein: each asterisk (*) in A units denotes a point of covalent bonding with an asterisk in B units, and each asterisk (*) in B units denotes a point of covalent bonding with an asterisk in A units; r is an integer of 1-3; R is a fluorinated hydrocarbon containing at least two aromatic rings and at least one ether linkage between aromatic rings; the composition includes a multiplicity of A units and multiplicity of B units; and a portion of the connection points are terminated by endcapping nitrile groups. Also described are methods for producing the polymer and a microporous carbon material produced by pyrolysis of the porous polymer membrane. Also described are methods for using the polymer and microporous carbon material for gas or liquid separation, filtration, or purification. |
| FILED | Wednesday, November 03, 2021 |
| APPL NO | 17/517993 |
| CURRENT CPC | Separation B01D 53/228 (20130101) B01D 61/027 (20130101) B01D 69/02 (20130101) B01D 71/62 (20130101) B01D 2325/02 (20130101) B01D 2325/04 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/065 (20130101) C08G 73/0644 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145104 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Ana Carolina Mazarin de Moraes (Chicago, Illinois); Jung-Woo Ted Seo (Naperville, Illinois) |
| ABSTRACT | The invention relates to printable ion-conductive and viscosity-tunable inks based on two-dimensional (2D) insulators, forming methods and applications of the inks. The 2D insulating material based printable ink includes at least one solvent; and an exfoliated composition dispersed in the at least one solvent. The exfoliated composition includes a 2D insulating material and a dispersant and stabilizing agent. The printed structures of the 2D insulating material based printable ink possess high ionic conductivity, chemical and thermal stability, and electrically insulating character, which are an ideal set of characteristics for printable battery components such as separators and solid electrolytes. |
| FILED | Wednesday, March 11, 2020 |
| APPL NO | 17/438967 |
| CURRENT CPC | Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 3/006 (20130101) B41M 5/0023 (20130101) B41M 5/0047 (20130101) B41M 7/009 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/14 (20130101) C09D 11/033 (20130101) C09D 11/36 (20130101) C09D 11/037 (20130101) Original (OR) Class C09D 11/322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145165 | GOUAL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WYOMING (Laramie, Wyoming) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lamia GOUAL (Laramie, Wyoming); Kaustubh Shriram RANE (Laramie, Wyoming); Bingjun ZHANG (Laramie, Wyoming) |
| ABSTRACT | In one embodiment, a method for recovery of an oil from a porous medium comprises contacting the porous medium with an aqueous nanofluid, solubilizing oil from the porous medium via the nanoparticles to form a dispersion comprising the oil and the aqueous nanofluid, and collecting at least some of the dispersion. The aqueous nanofluid may contain a combination of amphiphilic quantum dots and hydrophilic quantum dots, in a continuous phase. At least 90% of the quantum dot nanoparticles may have an aspect ratio of from 1:1 to 1:6. In another embodiment, a method for recovery of an oil from a porous medium includes adding quantum dots to foaming surfactants to enhance foam lamella stability under reservoir conditions and provide conformance and mobility control in porous media and hydraulic fractures. |
| FILED | Monday, November 01, 2021 |
| APPL NO | 17/516275 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/584 (20130101) Original (OR) Class C09K 8/594 (20130101) C09K 2208/10 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145295 | Church et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of HarvardCollege (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of HarvardCollege (Cambridge, Massachusetts) |
| INVENTOR(S) | George M. Church (Cambridge, Massachusetts); Daniel J. Wiegand (Cambridge, Massachusetts); Richard E. Kohman (Cambridge, Massachusetts); Erkin Kuru (Cambridge, Massachusetts); Jonathan Rittichier (Cambridge, Massachusetts); Nicholas Conway (Cambridge, Massachusetts) |
| ABSTRACT | Described herein are methods for the controlled de novo synthesis of RNA oligonucleotides using enzymatic catalysis. For example, provided herein are methods for preparing RNA oligonucleotides via controlled, template-independent addition of nucleotides to an initiator oligonucleotide 3′-terminus via enzymatic catalysis (also known as terminal transferase activity). Single nucleotides can be iteratively added by a compatible polymerase (e.g., a poly(N) polymerase such as a poly(U) polymerase) until a desired RNA oligonucleotide sequence is synthesized. Also provided are nucleotides and polymerases useful in the methods described herein. |
| FILED | Friday, October 11, 2019 |
| APPL NO | 17/283728 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1282 (20130101) C12N 15/113 (20130101) Original (OR) Class C12N 2310/321 (20130101) C12N 2310/322 (20130101) C12N 2310/3231 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 19/34 (20130101) Enzymes C12Y 207/07052 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145421 | Theaker et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of North Dakota (Grand Forks, North Dakota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nolan Theaker (Grand Forks, North Dakota); Daniel Laudal (Grand Forks, North Dakota) |
| ABSTRACT | A method for extracting rare earth elements and critical minerals including adding an acid to a mixture comprising organically bound rare earth elements. The mixture is maintained at a pH of 0.25 to 4 for a period of time, resulting in a liquor and a leached mixture. The liquor is removed from the leached mixture to form a dewatered cake. The dewatered cake is washed to form a washing liquid. The washing liquid is recycled to create a second slurry comprising organically bound rare earth elements. |
| FILED | Thursday, November 04, 2021 |
| APPL NO | 17/519341 |
| CURRENT CPC | Separation B01D 11/028 (20130101) B01D 11/0288 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/06 (20130101) C22B 59/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145422 | Dittrich et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wayne State University (Detroit, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Timothy M. Dittrich (Grosse Pointe Woods, Michigan); Matthew J. Allen (Plymouth, Michigan); Mohammed Dardona (Garden City, Michigan); Jessica L. Hovey (Garden City, Michigan) |
| ABSTRACT | A process for making modified diethylenetriaminepentaacetic acid (DTPA)-associated media for use in solid-liquid extraction of rare earth elements is disclosed. The process includes functionalizing DTPA with hydrophobic groups to form modified DTPA; dissolving the modified DTPA into a methanol solution; loading the modified DTPA solution to a solid support; rotating the modified DTPA-loaded solid support to allow for association; and removing the methanol to obtain the modified-DTPA-associated media. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/520869 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/22 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/24 (20130101) C22B 59/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145480 | Tucker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Tucker (Piedmont, California); Emir Dogdibegovic (Oakland, California); Ruofan Wang (Berkeley, California) |
| ABSTRACT | This disclosure provides systems, methods, and apparatus related to metal-supported solid oxide electrochemical devices. In one aspect, a stainless steel support of a device is oxidized. A coating is deposited on an oxygen-electrode side of the stainless steel support of the device. The coating is operable to reduce chromium evaporation from the stainless steel support. A structure including an oxygen catalyst on the oxygen-electrode side of the device and a fuel catalyst on a fuel-electrode side of the stainless steel support of the device, with an electrolyte disposed between the oxygen catalyst and the fuel catalyst, is formed. The device is thermally treated at a temperature of about 10° C. to 400° C. above an operating temperature of about 600° C. to 800° C. of the device, the oxygen-electrode side of the device being in an oxidizing atmosphere and the fuel-electrode side of the device being in a reducing atmosphere. |
| FILED | Wednesday, May 06, 2020 |
| APPL NO | 17/609353 |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 11/04 (20130101) Original (OR) Class Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8803 (20130101) H01M 4/9033 (20130101) H01M 8/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145486 | McCall et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California); Eck Industries, Inc. (Manitowoc, Wisconsin); UT-Battelle, LLC (Oak Ridge, Tennessee); University of Tennessee Research Foundation (Knoxville, Tennessee); Iowa State University Research Foundation, Inc. (Ames, Iowa) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Scott K. McCall (Livermore, California); David Weiss (Manitowoc, Wisconsin); Michael S. Kesler (Knoxville, Tennessee); Michael J. Thompson (Kingston, Tennessee); Orlando Rios (Knoxville, Tennessee); Hunter B. Henderson (Livermore, California); Zachary Cole Sims (Knoxville, Tennessee); Ryan T. Ott (Ames, Iowa) |
| ABSTRACT | A product includes an aluminum alloy having an anodized layer. The alloy has a bulk composition including at least 1 wt. % of one or more rare earth elements (REEs). A product includes microstructures extending across a boundary defined between an anodized layer and an unoxidized alloy. Each microstructure includes an intermetallic phase transitioning to an oxidized intermetallic phase across the boundary. A product includes an anodized layer where up to 90% of a thickness of the layer includes voids resulting at least in part from dissolution of a rare earth element oxidized intermetallic phase. The voids are in a morphology of the dissolved oxidized intermetallic phase. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 17/522745 |
| CURRENT CPC | Alloys C22C 21/04 (20130101) Processes for the Electrolytic or Electrophoretic Production of Coatings; Electroforming; Apparatus Therefor C25D 11/045 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146305 | Tung et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel Tung (Stanley, New Mexico); Randal L. Schmitt (Tijeras, New Mexico) |
| ABSTRACT | A laser absorptivity measurement device uses a linearly polarized incident beam, an optical configuration comprising an internal polarizing beamsplitter that transmits the linearly polarized incident beam and a quarter-wave plate that converts linearly polarized incident beam into a circularly polarized incident beam that is reflected off a processing substrate. The quarter-wave plate and polarizing beamsplitter can then direct the reflected light back into an integrating volume, where the power of the reflected light can be measured by a photodetector. The laser absorptivity measurement device is capable of making real-time absorption efficiency measurements of a variety of laser-based processes, including laser welding and brazing, additive manufacturing, and laser marking. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 17/522123 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) G01J 1/0429 (20130101) Original (OR) Class G01J 2001/446 (20130101) Optical Elements, Systems, or Apparatus G02B 5/3083 (20130101) G02B 27/283 (20130101) G02B 27/286 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220147379 | Urias et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | National Technology and Engineering Solutions of Sandia, LLC (Albuquerque, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Vincent Urias (Albuquerque, New Mexico); Brian P. Van Leeuwen (Albuquerque, New Mexico); William M.S. Stout (Albuquerque, New Mexico); Michael Kunz (Gretna, Nebraska) |
| ABSTRACT | A method of automating emulations is provided. The method comprising collecting publicly available network data over a predefined time interval, wherein the collected network data might comprise structured and unstructured data. Any unstructured data is converted into structured data. The original and converted structured data is stored in a database and compared to known network vulnerabilities. An emulated network is created according to the collected network data and the comparison of the structured data with known vulnerabilities. Virtual machines are created to run on the emulated network. Director programs and guest actor programs are run on the virtual machines, wherein the actor programs imitate real user behavior on the emulated network. The director programs deliver task commands to the guest actor programs to imitate real user behavior. The imitated behavior is presented to a user via an interface. |
| FILED | Tuesday, November 10, 2020 |
| APPL NO | 17/094542 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4881 (20130101) G06F 9/45558 (20130101) Original (OR) Class G06F 16/289 (20190101) G06F 16/2336 (20190101) G06F 21/566 (20130101) G06F 2009/45562 (20130101) G06F 2009/45595 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148751 | O'Hara |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Matthew J. O'Hara (Richland, Washington) |
| ABSTRACT | A new column-based purification system and approach are described for rapid separation and purification of the alpha-emitting therapeutic radioisotope 211At from dissolved cyclotron targets that provide highly reproducible product results with excellent 211At species distributions and high antibody labeling yields compared with prior art manual extraction results of the prior art that can be expected to enable enhanced production of purified 211At isotope products suitable for therapeutic medical applications such as treatment of cancer in human patients. |
| FILED | Thursday, January 27, 2022 |
| APPL NO | 17/586647 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/00 (20130101) Separation B01D 15/12 (20130101) B01D 15/14 (20130101) B01D 15/20 (20130101) B01D 15/426 (20130101) B01D 59/20 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/001 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148752 | Snow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mathew S. Snow (Idaho Falls, Idaho); Mathew T. Kinlaw (Idaho Falls, Idaho) |
| ABSTRACT | A method of producing enriched 47Sc comprises irradiating a V structure comprising 51V with at least one incident photon beam having an endpoint energy within a range of from about 14 MeV to about 44 MeV to convert at least some of the 51V to 47Sc and form a 47Sc-containing structure. The 47Sc of the 47Sc-containing structure is separated from additional components of the 47Sc-containing structure using a chromatography process. Systems and apparatuses for producing enriched 47Sc are also described. |
| FILED | Tuesday, May 05, 2020 |
| APPL NO | 17/594995 |
| CURRENT CPC | Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/065 (20130101) C22B 59/00 (20130101) Conversion of Chemical Elements; Radioactive Sources G21G 1/04 (20130101) Original (OR) Class G21G 2001/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148802 | Baker et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Richard Thuss (, None); Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander Baker (Pleasanton, California); Scott K. McCall (Livermore, California); Harry B. Radousky (San Leandro, California); Nathan Woollett (Pleasanton, California); Richard Thuss (Berryville, Virginia) |
| ABSTRACT | A product includes an array of cold spray-formed structures. Each of the structures is characterized by having a defined feature size in at least one dimension of less than 100 microns as measured in a plane of deposition of the structure, at least 90% of a theoretical density of a raw material from which the structure is formed, and essentially the same functional properties as the raw material. A product includes a cold spray-formed structure characterized by having a defined feature size in at least one dimension of less than 100 microns as measured in a plane of deposition of the structure, at least 90% of a theoretical density of a raw material from which the structure is formed, and essentially the same functional properties as the raw material. |
| FILED | Thursday, November 12, 2020 |
| APPL NO | 17/096699 |
| CURRENT CPC | Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/01 (20160101) C23C 4/12 (20130101) Magnets; Inductances; Transformers; Selection of Materials for Their Magnetic Properties H01F 7/02 (20130101) H01F 41/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148818 | ZHU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado); Board of Trustees of Northern Illinois University (DeKalb, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kai ZHU (Littleton, Colorado); Fei ZHANG (Tianjin, China PRC); Tao XU (Naperville, Illinois) |
| ABSTRACT | The present disclosure relates to a device that includes a first layer having an active material and a stabilizing material, where the active material includes a semiconductor, the stabilizing material includes at least one of an oligomer, an elastomer, a polymer, and/or a resin, and the stabilizing material provides to the device an improved performance metric compared to a device constructed of the first layer but constructed of only the active material (i.e., in the absence of the stabilizing material). |
| FILED | Wednesday, November 03, 2021 |
| APPL NO | 17/517830 |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/0036 (20130101) H01G 9/2009 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0003 (20130101) H01L 51/0077 (20130101) H01L 51/0094 (20130101) H01L 51/4253 (20130101) H01L 51/4293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148819 | Blackburn et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeffrey Lee Blackburn (Golden, Colorado); Ji Hao (Santa Clara, California) |
| ABSTRACT | The present disclosure relates to a device that includes a perovskite nanocrystal (NC) layer, a charge separating layer, an insulating layer, a gate electrode, a cathode, and an anode, where the charge separating layer is positioned between the perovskite NC layer and the insulating layer, the insulating layer is positioned between the charge separating layer and the gate electrode, and the cathode and the anode both electrically contact the charge separating layer and the insulating layer. In some embodiments of the present disclosure, the device may be configured to operate as at least one of a photodetector, an optical switching device, and/or a neuromorphic switching device. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 17/522794 |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/44 (20130101) Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/2009 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0077 (20130101) H01L 51/428 (20130101) H01L 51/4253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149348 | Vissers |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Vissers Battery Corporation (Wheaton, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Daniel R. Vissers (Wheaton, Illinois) |
| ABSTRACT | A battery includes a fluid negative electrode and a fluid positive electrode separated by a solid electrolyte at least when the electrodes and electrolyte are at an operating temperature. The solid electrolyte comprises a salt formed by ions of the negative electrode material forming the fluid negative electrode. In one example, the fluid negative electrode comprises lithium (Li), the fluid positive electrode comprises sulfur (S) and the solid electrolyte comprises lithium iodide (LiI). |
| FILED | Thursday, January 20, 2022 |
| APPL NO | 17/579918 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/136 (20130101) Original (OR) Class H01M 4/0471 (20130101) H01M 4/1397 (20130101) H01M 10/39 (20130101) H01M 10/63 (20150401) H01M 2004/028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149378 | Archer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lynden A. Archer (Ithaca, New York); Jingxu Zheng (Shenzen, China PRC); Tian Tang (Nanchang, China PRC); Qing Zhao (Tianjin, China PRC) |
| ABSTRACT | Conducting coatings disposed on a metal member. The conducting coatings may have a desired texture and provide homoepitaxial or heteroepitaxial coating of an electrodeposited layer. A conducting coating may be formed by applying a shear force during deposition of the conducting coating. The conducting coatings may be used in anodes of various electrochemical devices. A conducting coating, which may be part of an electrochemical device, may have an electrochemically deposited layer disposed on at least a portion of a surface of the conducting coating. The electrochemically deposited layer may be reversibly electrochemically deposited. |
| FILED | Monday, April 27, 2020 |
| APPL NO | 17/604860 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/134 (20130101) H01M 4/0452 (20130101) H01M 4/625 (20130101) Original (OR) Class H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149407 | Edmundson et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | W. L. Gore and Associates, Inc. (Newark, Delaware) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Edmundson (Rancho Palos Verdes, California); F. Colin Busby (Newark, Delaware) |
| ABSTRACT | Methods and compositions for making fuel cell components are described. In one embodiment, the method comprises providing a substrate, and forming or adhering an electrode on the substrate, wherein the forming includes depositing an aqueous mixture comprising water, a water-insoluble component, a catalyst, and an ionomer. The water-insoluble component comprises a water-insoluble alcohol, a water-insoluble carboxylic acid, or a combination thereof. The use of such water-insoluble components results in a stable liquid medium with reduced reticulation upon drying, reduced dissolution of the substrate, and reduced penetration of the pores of the substrate. |
| FILED | Monday, January 03, 2022 |
| APPL NO | 17/567471 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8807 (20130101) H01M 4/9083 (20130101) H01M 8/1004 (20130101) Original (OR) Class H01M 2008/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149408 | Edmundson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | W. L. Gore and Associates, Inc. (Newark, Delaware) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Edmundson (Rancho Palos Verdes, California); F. Colin Busby (Newark, Delaware) |
| ABSTRACT | Methods and compositions for making fuel cell components are described. In one embodiment, the method comprises providing a substrate, and forming or adhering an electrode on the substrate, wherein the forming includes depositing an aqueous mixture comprising water, a water-insoluble component, a catalyst, and an ionomer. The water-insoluble component comprises a water-insoluble alcohol, a water-insoluble carboxylic acid, or a combination thereof. The use of such water-insoluble components results in a stable liquid medium with reduced reticulation upon drying, reduced dissolution of the substrate, and reduced penetration of the pores of the substrate. |
| FILED | Monday, January 03, 2022 |
| APPL NO | 17/567621 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/8807 (20130101) H01M 4/9083 (20130101) H01M 8/1004 (20130101) Original (OR) Class H01M 2008/1095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149417 | Song et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | ESS Tech, Inc. (Wilsonville, Oregon) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yang Song (West Linn, Oregon); Craig E. Evans (West Linn, Oregon) |
| ABSTRACT | A method of cleansing a redox flow battery system may include operating the redox flow battery system in a charge, discharge, or idle mode, and responsive to a redox flow battery capacity being less than a threshold battery capacity, mixing the positive electrolyte with the negative electrolyte. In this way, battery capacity degradation following cyclic charging and discharging of the redox flow battery system can be substantially reduced. |
| FILED | Monday, December 20, 2021 |
| APPL NO | 17/645293 |
| CURRENT CPC | Image or Video Recognition or Understanding G06V 40/1306 (20220101) G06V 40/1394 (20220101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/188 (20130101) Original (OR) Class H01M 8/0693 (20130101) H01M 8/04186 (20130101) H01M 8/04611 (20130101) H01M 8/04932 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149450 | SMITH et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kandler Alan SMITH (Golden, Colorado); Shriram SANTHANAGOPALAN (Broomfield, Colorado); Nathaniel Alexander SUNDERLIN (Golden, Colorado); Andrew Michael COLCLASURE (Morrison, Colorado); Chunmei BAN (Golden, Colorado); Xuemin LI (Lakewood, Colorado); Judy C. NETTER (Westminster, Colorado); Donal Patrick FINEGAN (Golden, Colorado); Kaitlin Elizabeth FINK (Lakewood, Colorado); Jaclyn Elizabeth COYLE (Westminster, Colorado) |
| ABSTRACT | Among other things, the present disclosure relates to re-purposing used lithium-ion batteries. The present disclosure includes treating an electrode using a solvent prior to electrochemically relithiating the electrode. In some embodiments, the relithiation may be done using a roll-to-roll device, wherein the electrode may be secured on a first pin and a second pin, then it may be unwound and submerged in an electrolyte solution. Lithium ions may be inserted into the electrode using a voltage. The layer of lithium may provide lithium ions to the electrode. |
| FILED | Friday, October 29, 2021 |
| APPL NO | 17/514004 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/049 (20130101) H01M 4/139 (20130101) H01M 10/54 (20130101) Original (OR) Class H01M 10/0525 (20130101) H01M 10/0587 (20130101) H01M 2004/8689 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220150226 | Edgar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Battelle Memorial Institute (Richland, Washington) |
| ASSIGNEE(S) | Battelle Memorial Institute (Richland, Washington) |
| INVENTOR(S) | Thomas W. Edgar (Richland, Washington); Thomas E. Carroll (Richland, Washington); Garret E. Seppala (Richland, Washington) |
| ABSTRACT | Computing system operational methods and apparatus are described. According to one aspect, a computing system operational method includes accessing user information regarding a user logging onto a computing device of the computing system, processing the user information to determine if the user information is authentic, as a result of the processing determining that the user information is authentic, first enabling the computing device to execute an application segment, and as a result of the processing determining that the user information is authentic, second enabling the application segment to communicate data externally of the computing device via one of a plurality of network segments of the computing system. |
| FILED | Wednesday, January 26, 2022 |
| APPL NO | 17/584885 |
| CURRENT CPC | Electric Digital Data Processing G06F 9/45558 (20130101) G06F 21/316 (20130101) G06F 2009/45587 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 41/0803 (20130101) H04L 63/20 (20130101) H04L 63/102 (20130101) H04L 63/164 (20130101) H04L 63/0428 (20130101) Original (OR) Class H04L 67/2804 (20130101) H04L 67/2814 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220151055 | Posen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | FERMI RESEARCH ALLIANCE, LLC (Batavia, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sam Posen (Arlington Heights, Illinois); Anna Grassellino (Batavia, Illinois) |
| ABSTRACT | A system and method for treating a cavity comprises arranging a niobium structure in a coating chamber, the coating chamber being arranged inside a furnace, coating the niobium structure with tin thereby forming an Nb3Sn layer on the niobium structure, and doping the Nb3Sn layer with nitrogen, thereby forming a nitrogen doped Nb3Sn layer on the niobium structure. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 17/581353 |
| CURRENT CPC | Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 19/00 (20130101) C01G 33/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/06 (20130101) C23C 16/045 (20130101) C23C 16/4485 (20130101) Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/00 (20130101) H01L 39/24 (20130101) H01L 39/2406 (20130101) H01L 39/2432 (20130101) H01L 39/2438 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/06 (20130101) H01P 11/008 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 7/20 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20220142200 | Gibbons et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Prairie AquaTech LLC (Brookings, South Dakota) |
| ASSIGNEE(S) | South Dakota State University (Brookings, South Dakota) |
| INVENTOR(S) | William Gibbons (Brookings, South Dakota); Michael Brown (Volga, South Dakota) |
| ABSTRACT | The present invention describes a bio-based process to produce high quality protein concentrate (HQPC) by converting plant derived celluloses into bioavailable protein via aerobic incubation, including the use of such HQPC so produced as a nutrient, including use as a fish meal replacement in aquaculture diets. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 17/581535 |
| CURRENT CPC | Protein Compositions for Foodstuffs; Working-up Proteins for Foodstuffs; Phosphatide Compositions for Foodstuffs A23J 1/125 (20130101) Original (OR) Class A23J 1/148 (20130101) Fodder A23K 10/14 (20160501) A23K 10/38 (20160501) A23K 20/147 (20160501) A23K 50/80 (20160501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220142556 | Faghih et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Houston System (Houston, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rose T. Faghih (Houston, Texas); Dilranjan S. Wickramasuriya (Houston, Texas); Md. Rafiul Amin (Houston, Texas) |
| ABSTRACT | A system for estimating a state of the nervous system includes at least one sensor configured to sense a continuously variable non-neural physiological condition as sensed data, a relatively low performance processing device configured to receive the sensed data and estimate a state of a nervous system based on the sensed data, and a relatively high performance computing device configured to provide updates to the processing device to improve the estimate of the state of the nervous system. A method for estimating a state of the nervous system includes obtaining sensed data indicative of a continuously variable non-neural physiological condition, estimating a state of a nervous system based on the sensed data, outputting the estimated state of the nervous system, and receiving updates to improve the estimating. |
| FILED | Friday, October 29, 2021 |
| APPL NO | 17/514129 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/024 (20130101) A61B 5/0205 (20130101) A61B 5/0531 (20130101) A61B 5/4035 (20130101) Original (OR) Class A61B 5/4836 (20130101) A61B 5/4839 (20130101) A61B 5/7267 (20130101) A61B 5/14546 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143199 | BLAKE et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Palo Alto, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tim R. BLAKE (Palo Alto, California); Paul WENDER (Palo Alto, California); Robert M. WAYMOUTH (Palo Alto, California); Ronald LEVY (Palo Alto, California); Ole Audun Werner HAABETH (Palo Alto, California); Rebecca MCCLELLAN (Palo Alto, California); Adrienne SALLETS (Palo Alto, California) |
| ABSTRACT | There are provided herein, inter alia, cationic amphipathic polymers, complexes, and compositions comprising same, and methods for their use including for the delivery of therapeutic, diagnostic and imaging agents, including nucleic acids, into a cell. The complexes, compositions and methods may facilitate delivery and targeted release of the therapeutic, diagnostic and imaging agents to particular cell types and tissues. |
| FILED | Friday, January 31, 2020 |
| APPL NO | 17/427362 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/007 (20130101) A61K 47/549 (20170801) A61K 47/593 (20170801) Original (OR) Class A61K 48/0041 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 73/028 (20130101) C08G 73/0293 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143570 | Bollas et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | University of Connecticut (Farmington, Connecticut) |
| INVENTOR(S) | George M. Bollas (Tolland, Connecticut); Chen Chen (Willington, Connecticut) |
| ABSTRACT | Systems/methods for continuous operation of fixed bed reactors using gaseous fuels for the purpose of power generation through integration with a combined cycle power plant are provided. The fixed bed reactors are assumed to operate in a semi-batch mode composed of reactor modules that are integrated into module trains that comprise the chemical-looping combustion island of the power plant. The scheduling of each reactor train is cast as an optimization problem that maximizes thermodynamic efficiency subject to constraints imposed to each reactor and the entire island. When the chemical-looping reactors are arranged cyclically, each feeding to or being fed from another reactor, in an operating scheme that mimics simulated moving bed reactors, the thermodynamic efficiency of the reactor island can be improved. Allowing the reversal of module order in the cyclically arranged reactor modules further improves the overall thermodynamic efficiency (to 84.7%), while satisfying constraints imposed for carbon capture, fuel conversion, power plant safety and oxygen carrier stability. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/521227 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 19/0033 (20130101) Original (OR) Class B01J 19/2435 (20130101) B01J 2219/0004 (20130101) B01J 2219/00031 (20130101) B01J 2219/00033 (20130101) B01J 2219/00121 (20130101) Ammonia; Cyanogen; Compounds Thereof C01C 1/0488 (20130101) Methods or apparatus for combustion using fluid fuel or Solid Fuel Suspended In Air F23C 3/002 (20130101) F23C 6/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143581 | Hamers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert John Hamers (Madison, Wisconsin); Shuo Li (Madison, Wisconsin) |
| ABSTRACT | Plasmonic diamond films are provided. In an embodiment, a plasmonic diamond film comprises a plurality of plasmonic nanoparticles encapsulated by diamond and distributed on an underlying surface of diamond. Methods of forming the plasmonic diamond films are also provided. |
| FILED | Wednesday, December 15, 2021 |
| APPL NO | 17/551268 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 21/18 (20130101) B01J 23/50 (20130101) Original (OR) Class B01J 35/004 (20130101) B01J 35/0006 (20130101) B01J 35/023 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/18 (20130101) C23C 16/274 (20130101) C23C 16/0281 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220143592 | Bae et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Chulsung Bae (Cohoes, New York); Angela Dee Mohanty (Clifton Park, New York) |
| ABSTRACT | Embodiments of the invention relate generally to anion exchange membranes and, more particularly, to anion exchange membranes comprising a styrene block copolymer and methods for their manufacture. In one embodiment, the invention provides a polymer according to formula IV, wherein x and y are mol %, QA is or each of R1 and R2 is, independently, a linear alkyl chain or a cyclic alkyl chain, and Z is selected from a group consisting of: a linear alkyl chain, a cyclic alkyl chain, and an alkylene ether chain. |
| FILED | Tuesday, June 15, 2021 |
| APPL NO | 17/347805 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 41/14 (20130101) Original (OR) Class Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 8/04 (20130101) C08F 8/24 (20130101) C08F 8/42 (20130101) C08F 8/44 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 13/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/083 (20130101) H01M 8/103 (20130101) H01M 8/1023 (20130101) H01M 2008/1095 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144662 | HEJAZI et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Davoud HEJAZI (Malden, Massachusetts); Swastik KAR (Belmont, Massachusetts); Renda TAN (Malden, Massachusetts) |
| ABSTRACT | Methods for making of nanomaterials from a bulk source material involve heating the material in an inert atmosphere, whereby a material having at least one nanometer scale dimension is formed on a nearby substrate surface. The heated bulk source material forms a vapor phase which is deposited in the form of the nanomaterial on a growth surface of the substrate. The methods require no complex machinery or devices, unlike chemical vapor deposition, and can be tuned to provide different forms of nanomaterials, such as two-dimensional or other crystalline forms. The methods can be used to make two-dimensional semiconductor materials and semiconductor devices. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 17/523861 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Compounds Containing Metals Not Covered by Subclasses C01D or C01F C01G 39/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144714 | Duan et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Xiangfeng Duan (Los Angeles, California); Yu Huang (Los Angeles, California); Xiang Xu (Los Angeles, California) |
| ABSTRACT | A ceramic aerogel includes a porous framework including interconnected double-paned wall structures of a ceramic material, wherein each double-paned wall structure includes a pair of walls spaced apart by a gap. |
| FILED | Thursday, January 23, 2020 |
| APPL NO | 17/427277 |
| CURRENT CPC | Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/14 (20130101) C04B 35/80 (20130101) C04B 35/583 (20130101) C04B 35/62884 (20130101) C04B 38/00 (20130101) C04B 38/0067 (20130101) C04B 38/0074 (20130101) C04B 38/0615 (20130101) Original (OR) Class C04B 2235/386 (20130101) C04B 2235/614 (20130101) C04B 2235/767 (20130101) C04B 2235/963 (20130101) C04B 2235/3418 (20130101) C04B 2235/3834 (20130101) C04B 2235/9607 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/76 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144899 | Bothfeld et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northwestern University (Evanston, Illinois) |
| ASSIGNEE(S) | Northwestern University (Evanston, Illinois) |
| INVENTOR(S) | William H. Bothfeld (Chicago, Illinois); Keith E.J. Tyo (Evanston, Illinois) |
| ABSTRACT | The present disclosure relates generally to modified bacteria, such as E. coli, with modification in the expression of at least one gene encoding a type I and/or type II toxin-antitoxin (TA) system protein and/or at least one gene encoding a structural protein that modulates ribosomes and methods of using the disclosed bacteria for producing a biological compound of interest. The modifications of the bacteria result in enhanced bioproduction. |
| FILED | Tuesday, November 09, 2021 |
| APPL NO | 17/522441 |
| CURRENT CPC | Peptides C07K 14/245 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/70 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 5/002 (20130101) C12P 7/42 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220144916 | MAYNARD et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jennifer A. MAYNARD (Austin, Texas); Ellen WAGNER (Larkspur, Colorado); Ahlam N. QERQEZ (Cedar Park, Texas); Annalee NGUYEN (Austin, Texas) |
| ABSTRACT | Provided herein are engineered T-cell receptors (TCRs) having nanomolar affinity for the immuno-dominant pp65 peptide residing between residues 495-503 (NLV) in complex with HLA-A2*02:01. The TCRs may be membrane-hound TCRs, soluble TCRs, chimeric TCRs, or chimeric antigen receptors. Also provided are methods of using the engineered TCRs to treat diseases, monitor disease progression, monitor vaccine efficacy, and detecting NLV/A2 presentation on the surface of cells. |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 17/430319 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) A61K 45/06 (20130101) A61K 47/6425 (20170801) Peptides C07K 14/7051 (20130101) Original (OR) Class C07K 16/2809 (20130101) C07K 2317/53 (20130101) C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145037 | Nejati et al. |
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| FUNDED BY |
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| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Siamak Nejati (Lincoln, Nebraska); Mona Bavarian (Lincoln, Nebraska); Mahdi Mohammadi Ghaleni (Lincoln, Nebraska) |
| ABSTRACT | Provided here are compositions and methods for preparing porous omniphobic surfaces with desirable chemical and structural properties. The methods include sequential initiated chemical vapor deposition (iCVD) of low surface-energy materials onto a variety of substrates. |
| FILED | Friday, November 05, 2021 |
| APPL NO | 17/520611 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/60 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/365 (20130101) Original (OR) Class C08J 2327/16 (20130101) C08J 2427/18 (20130101) C08J 2433/16 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/002 (20130101) C09D 127/18 (20130101) C09D 133/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145104 | Hersam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | NORTHWESTERN UNIVERSITY (Evanston, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark C. Hersam (Wilmette, Illinois); Ana Carolina Mazarin de Moraes (Chicago, Illinois); Jung-Woo Ted Seo (Naperville, Illinois) |
| ABSTRACT | The invention relates to printable ion-conductive and viscosity-tunable inks based on two-dimensional (2D) insulators, forming methods and applications of the inks. The 2D insulating material based printable ink includes at least one solvent; and an exfoliated composition dispersed in the at least one solvent. The exfoliated composition includes a 2D insulating material and a dispersant and stabilizing agent. The printed structures of the 2D insulating material based printable ink possess high ionic conductivity, chemical and thermal stability, and electrically insulating character, which are an ideal set of characteristics for printable battery components such as separators and solid electrolytes. |
| FILED | Wednesday, March 11, 2020 |
| APPL NO | 17/438967 |
| CURRENT CPC | Printing, Duplicating, Marking, or Copying Processes; Colour Printing, B41M 3/006 (20130101) B41M 5/0023 (20130101) B41M 5/0047 (20130101) B41M 7/009 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 11/14 (20130101) C09D 11/033 (20130101) C09D 11/36 (20130101) C09D 11/037 (20130101) Original (OR) Class C09D 11/322 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145165 | GOUAL et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WYOMING (Laramie, Wyoming) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lamia GOUAL (Laramie, Wyoming); Kaustubh Shriram RANE (Laramie, Wyoming); Bingjun ZHANG (Laramie, Wyoming) |
| ABSTRACT | In one embodiment, a method for recovery of an oil from a porous medium comprises contacting the porous medium with an aqueous nanofluid, solubilizing oil from the porous medium via the nanoparticles to form a dispersion comprising the oil and the aqueous nanofluid, and collecting at least some of the dispersion. The aqueous nanofluid may contain a combination of amphiphilic quantum dots and hydrophilic quantum dots, in a continuous phase. At least 90% of the quantum dot nanoparticles may have an aspect ratio of from 1:1 to 1:6. In another embodiment, a method for recovery of an oil from a porous medium includes adding quantum dots to foaming surfactants to enhance foam lamella stability under reservoir conditions and provide conformance and mobility control in porous media and hydraulic fractures. |
| FILED | Monday, November 01, 2021 |
| APPL NO | 17/516275 |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Materials for Miscellaneous Applications, Not Provided for Elsewhere C09K 8/584 (20130101) Original (OR) Class C09K 8/594 (20130101) C09K 2208/10 (20130101) Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 43/168 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145350 | Bonito et al. |
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| FUNDED BY |
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| APPLICANT(S) | Board of Trustees of Michigan State University (East Lansing, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory Bonito (East Lansing, Michigan); Zhi-Yan Du (East Lansing, Michigan) |
| ABSTRACT | This application describes methods of using fungi to harvest algae. As illustrated herein the algae stick onto and are captured directly by the hyphae of the fungi. The fungi, the algae, or both can be modified to express heterologous proteins or other products. The methods facilitate harvesting of useful strains of algae and the products made by such algae. |
| FILED | Friday, February 28, 2020 |
| APPL NO | 17/435530 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/12 (20130101) C12N 1/14 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 39/00 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146430 | Peterman et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | OndaVia, Inc. (Hayward, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark C. Peterman (Fremont, California); Merwan Benhabib (San Francisco, California); Samuel Kleinman (Oakland, California) |
| ABSTRACT | A hand-held microfluidic testing device is provided that includes a housing having a cartridge receiving port, a cartridge for input to the cartridge receiving port having a sample input and a channel, where the channel includes a mixture of Raman-scattering nanoparticles and a calibration solution, where the calibration solution includes chemical compounds capable of interacting with a sample under test input to the cartridge and the Raman-scattering nanoparticles, and an optical detection system in the housing, where the optical detection system is capable of providing an illuminated electric field, where the illuminating electric field is capable of being used for Raman spectroscopy with the Raman-scattering nanoparticles and the calibration solution to analyze the sample under test input to the cartridge. |
| FILED | Tuesday, November 16, 2021 |
| APPL NO | 17/527844 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) B01L 2200/0652 (20130101) B01L 2300/087 (20130101) B01L 2300/0636 (20130101) B01L 2300/0654 (20130101) B01L 2300/0681 (20130101) B01L 2300/0867 (20130101) B01L 2400/0418 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/02 (20130101) G01J 3/18 (20130101) G01J 3/44 (20130101) G01J 3/0256 (20130101) G01J 3/0291 (20130101) G01J 3/4412 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/47 (20130101) G01N 21/49 (20130101) G01N 21/63 (20130101) G01N 21/65 (20130101) Original (OR) Class G01N 21/66 (20130101) G01N 21/68 (20130101) G01N 21/658 (20130101) G01N 21/4785 (20130101) G01N 27/44704 (20130101) G01N 27/44791 (20130101) G01N 30/6065 (20130101) G01N 30/6095 (20130101) G01N 33/18 (20130101) G01N 2021/651 (20130101) G01N 2030/0095 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146503 | VEMULAPATI et al. |
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| FUNDED BY |
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| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Sasank VEMULAPATI (Ithaca, New York); David ERICKSON (Ithaca, New York) |
| ABSTRACT | The present disclosure relates to, inter alia, devices, systems, and methods for use in the magnetic separation of biological entities from fluid samples. This device includes a magnetic separation chamber configured to receive a fluid sample for magnetic separation, where the magnetic separation chamber includes at least two magnets mounted on the surface or in the wall of the magnetic separation chamber. The device also includes a force provider configured to move the magnetic separation chamber in a side-to-side motion to mix and/or magnetize the fluid sample. In one embodiment, the magnetic separation chamber is in a form of a sleeve and comprises a substantially central channel for loading a vessel containing the fluid sample therein. The systems and methods of the present disclosure involve the use of this device to separate biological entities from fluid samples. |
| FILED | Wednesday, January 19, 2022 |
| APPL NO | 17/579528 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/4077 (20130101) G01N 33/54326 (20130101) Original (OR) Class G01N 33/56966 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146749 | Bandyopadhyay et al. |
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| FUNDED BY |
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| APPLICANT(S) | Saumil Bandyopadhyay (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Saumil Bandyopadhyay (Cambridge, Massachusetts); Dirk Robert ENGLUND (Brookline, Massachusetts) |
| ABSTRACT | The next-generation of optoelectronic systems will require efficient optical signal transfer between many discrete photonic components integrated onto a single substrate. While modern assembly processes can easily integrate thousands of electrical components onto a single board, photonic assembly is far more challenging due to the wavelength-scale alignment tolerances required. Here we address this problem by introducing a self-aligning photonic coupler insensitive to x, y, z displacement and angular misalignment. The self-aligning coupler provides a translationally invariant evanescent interaction between waveguides by intersecting them at an angle, which enables a lateral and angular alignment tolerance fundamentally larger than non-evanescent approaches such as edge coupling. This technology can function as a universal photonic connector interfacing photonic integrated circuits and microchiplets across different platforms. For example, it can be used in a self-aligning photonic circuit board that can be assembled more easily, with larger misalignment tolerances, than other complex optoelectronic systems. |
| FILED | Thursday, September 09, 2021 |
| APPL NO | 17/470803 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/125 (20130101) Original (OR) Class G02B 2006/12147 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148458 | Hong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Minsik Hong (Tucson, Arizona); Jerzy W. Rozenblit (Tucson, Arizona) |
| ABSTRACT | An adaptive force guidance system for laparoscopic surgery skills training includes self-adjusting fuzzy sliding mode controllers and switching mode controllers to provide proper force feedback. Using virtual fixtures, the system restrictS motions and/or guide a trainee to navigate a surgical instrument in a 3D space in a manner that mimics a human instructor who would teach trainees by holding their hands. The self-adjusting controllers incorporate human factors such as different force sensitivity and proficiency level. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/520852 |
| CURRENT CPC | Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/003 (20130101) G09B 23/285 (20130101) Original (OR) Class Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/63 (20180101) G16H 70/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148708 | NARAYANAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Shrikanth Sambasivan NARAYANAN (Santa Monica, California); Gayla MARGOLIN (Los Angeles, California); Adela C. AHLE (San Francisco, California); Theodora CHASPARI (College Station, Texas) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (LOS ANGELES, California) |
| INVENTOR(S) | Shrikanth Sambasivan NARAYANAN (Santa Monica, California); Gayla MARGOLIN (Los Angeles, California); Adela C. AHLE (San Francisco, California); Theodora CHASPARI (College Station, Texas) |
| ABSTRACT | A method for monitoring and understanding interpersonal relationships includes a step of monitoring interpersonal relations of a couple or group of interpersonally connected users with a plurality of smart devices by collecting data streams from the smart devices. Representations of interpersonal relationships are formed for increasing knowledge about relationship functioning and detecting interpersonally-relevant mood states and events. Feedback and/or goals are provided to one or more users to increase awareness about relationship functioning. |
| FILED | Monday, December 27, 2021 |
| APPL NO | 17/562647 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/165 (20130101) A61B 5/4803 (20130101) A61B 5/6801 (20130101) A61B 5/6898 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 20/70 (20180101) Original (OR) Class G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220148731 | Hawkins-Daarud et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrea J. Hawkins-Daarud (Houston, Texas); Leland S. Hu (Phoenix, Arizona); Kristin R. Swanson (Phoenix, Arizona); Teresa Wu (Gilbert, Arizona); Jing Li (Marietta, Georgia); Lujia Wang (Scottsdale, Arizona) |
| ABSTRACT | Genetic and/or other biological marker prediction data are generated based on inputting medical image data to a suitably trained machine learning model, where the output genetic prediction data not only indicate a prediction of genetic features and/or other biological markers for a subject, but also a measure of uncertainty in each of those predictions. As an example, a transductive learning Gaussian process model is used to generate the genetic and/or other biological marker predication data and corresponding predictive uncertainty data. As another example, a knowledge-infused global-local data fusion model can be used for spatial predictive modeling. |
| FILED | Thursday, November 11, 2021 |
| APPL NO | 17/524591 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0042 (20130101) A61B 5/055 (20130101) A61B 5/0263 (20130101) A61B 5/7267 (20130101) A61B 2576/026 (20130101) Computer Systems Based on Specific Computational Models G06N 5/022 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 5/20 (20190201) G16B 40/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/40 (20180101) G16H 50/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149305 | Armstrong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of the University of Arizona (Tucson, Arizona) |
| INVENTOR(S) | Neal R. Armstrong (Tucson, Arizona); Richard Clayton Shallcross (Tucson, Arizona) |
| ABSTRACT | The present invention provides compositions comprising a metal oxide electrode, a passivating agent on its surface, and a hybrid organic-inorganic perovskite active layer in contact with the metal oxide electrode surface. The presence of a passivating agent on the metal oxide surface increases stability and/or photovoltaic power conversion efficiency of the electronic component comprising a composition of the invention. |
| FILED | Sunday, February 09, 2020 |
| APPL NO | 17/429345 |
| CURRENT CPC | Capacitors; Capacitors, Rectifiers, Detectors, Switching Devices or Light-sensitive Devices, of the Electrolytic Type H01G 9/204 (20130101) H01G 9/2027 (20130101) H01G 9/2031 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0077 (20130101) H01L 51/0094 (20130101) H01L 51/105 (20130101) H01L 51/441 (20130101) Original (OR) Class H01L 51/5206 (20130101) H01L 51/5221 (20130101) H01L 51/5237 (20130101) H01L 2251/303 (20130101) H01L 2251/306 (20130101) H01L 2251/308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149902 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SYRACUSE UNIVERSITY (Syracuse, New York) |
| ASSIGNEE(S) | SYRACUSE UNIVERSITY (Syracuse, New York) |
| INVENTOR(S) | Biao Chen (Jamesville, New York); Yang Liu (San Jose, California); Janek Mroczek (Barneveld, New York) |
| ABSTRACT | A multiple-input multiple-output (MIMO) communication system that addresses three major challenges in airborne MIMO communications, namely, antenna blockage due largely to the movement and orientation of the airborne platforms, the presence of unknown interference inherent to the intended application, and the lack of channel state information (CSI) at the transmitter. The system is implemented on a Diagonal Bell-Labs Layered Space-Time (D-BLAST) MIMO architecture and includes spatial spreading to counter antenna blockage, temporal spreading to mitigate signal to interference and noise ratio degradation due to intended or unintended interference, and a simple low rate feedback scheme to enable real time adaptation in the absence of full transmitter CSI. |
| FILED | Wednesday, November 10, 2021 |
| APPL NO | 17/523538 |
| CURRENT CPC | Transmission H04B 7/26 (20130101) H04B 7/0413 (20130101) Original (OR) Class Transmission of Digital Information, e.g Telegraphic Communication H04L 25/0202 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149917 | Paramesh et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jeyanandh Paramesh (Pittsburgh, Pennsylvania); Susnata Mondal (Pittsburgh, Pennsylvania) |
| ABSTRACT | Disclosed herein is a new type of fully-connected, hybrid beamforming transceiver architecture. The transceiver described herein is bi-directional and can be configured as a transmit beamformer or a receive beamformer. A method and apparatus are described that allows the beamformer to operate in “carrier aggregated” mode, where communication channels in multiple disparate frequency bands can be simultaneously accessed. |
| FILED | Monday, January 24, 2022 |
| APPL NO | 17/582759 |
| CURRENT CPC | Transmission H04B 7/0617 (20130101) H04B 7/0634 (20130101) H04B 7/0686 (20130101) Original (OR) Class H04B 7/0842 (20130101) H04B 7/0868 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20220143748 | Reicks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Andrew R. Reicks (Lincoln, Nebraska); Craig Zuhlke (Lincoln, Nebraska); Alfred Tooru Tsubaki (Lincoln, Nebraska); Christos Argyropoulos (Lincoln, Nebraska); George Gogos (Lincoln, Nebraska); Mark Anderson (Lincoln, Nebraska); Dennis R. Alexander (Lincoln, Nebraska) |
| ABSTRACT | A method for laser-processing a metallic surface to produce a functionalized metallic surface comprises: providing a substrate having the metallic surface; applying a pulsed laser beam with a controlled fluence to a region of the metallic surface in an environment containing oxygen, wherein metal material in the region of the metallic surface ablates due to the applied pulsed laser beam and wherein at least a portion of the ablated metal material oxidizes and redeposits on the metallic surface to produce one or more oxidized-metal-coated structures; wherein the metallic surface having the one or more oxidized-metal-coated structures is the functionalized metallic surface. Optionally, the functionalized metallic surface has a higher hemispherical emissivity than the metallic surface free of the oxidized-metal-coated structures and prior to applying the pulsed laser beam under otherwise identical conditions. Optionally, the functionalized metallic surface is characterized by a hemispherical emissivity of at least 0.85. |
| FILED | Friday, November 12, 2021 |
| APPL NO | 17/525094 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/123 (20130101) B23K 26/352 (20151001) B23K 26/0624 (20151001) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145012 | KORNFIELD et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (PASADENA, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julia A. KORNFIELD (PASADENA, California); Ming-Hsin WEI (PASADENA, California) |
| ABSTRACT | Described herein are associative polymers capable of controlling a physical and/or chemical property of non-polar compositions and related compositions, methods and systems. Associative polymers herein described have a non-polar backbone and functional groups presented at ends of the non-polar backbone, with a number of the functional groups presented at the ends of the non-polar backbone formed by associative functional groups capable of undergoing an associative interaction with another associative functional group with an association constant (k) such that the strength of each associative interaction is less than the strength of a covalent bond between atoms and in particular less than the strength of a covalent bond between backbone atoms. |
| FILED | Monday, April 26, 2021 |
| APPL NO | 17/240028 |
| CURRENT CPC | Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 2438/01 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 61/08 (20130101) C08G 83/00 (20130101) C08G 83/005 (20130101) Original (OR) Class C08G 83/008 (20130101) C08G 2261/63 (20130101) C08G 2261/64 (20130101) C08G 2261/72 (20130101) C08G 2261/132 (20130101) C08G 2261/418 (20130101) C08G 2261/1644 (20130101) C08G 2261/3323 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/0008 (20130101) Compositions of Macromolecular Compounds C08L 101/02 (20130101) C08L 101/08 (20130101) C08L 101/025 (20130101) Fuels Not Otherwise Provided for; Natural Gas; Synthetic Natural Gas Obtained by Processes Not Covered by Subclasses C10G, C10K; Liquefied Petroleum Gas; Adding Materials to Fuels or Fires to Reduce Smoke or Undesirable Deposits or to Facilitate Soot Removal; Firelighters C10L 1/195 (20130101) C10L 1/236 (20130101) C10L 1/1658 (20130101) C10L 10/02 (20130101) C10L 10/08 (20130101) C10L 2230/22 (20130101) C10L 2250/04 (20130101) Pipe-line Systems; Pipe-lines F17D 1/17 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146498 | Vanapalli et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Texas Tech University System (Lubbock, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Siva A. Vanapalli (Lubbock, Texas); Taslim Anupom (Lubbock, Texas); Mizanur Rahman (Lubbock, Texas); Siddhartha Gupta (Lubbock, Texas) |
| ABSTRACT | The present invention includes a system and method for analyzing animals including: a media reservoir and a media pump in fluid communication with the media reservoir; a food reservoir and a food pump in fluid communication with the food reservoir; an input port in fluid communication with the media pump and the food pump; a microfluidic device in fluid communication with the input port including: a micropillar arena or a plurality of micropillar chambers; an outlet port in fluid communication with the microfluidic device; a light source positioned outside the micropillar arena to illuminate the interior of the micropillar arena; an imager positioned outside the micropillar arena to image the interior of the micropillar arena; and a controller coupled to the media pump, the food pump, the microfluidic device, the light source, and the imager. |
| FILED | Thursday, March 05, 2020 |
| APPL NO | 17/436194 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/50273 (20130101) B01L 3/502715 (20130101) B01L 2200/0684 (20130101) B01L 2300/0663 (20130101) B01L 2300/0883 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5085 (20130101) Original (OR) Class G01N 2333/43534 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146677 | Willett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Isaak Willett (Tucson, Arizona); Richard Herriman (Tucson, Arizona); Daniel Inigo (Tucson, Arizona) |
| ABSTRACT | A system and method for object detection in 3-dimensional space uses a ground up model that makes detecting objects faster and more accurate by combining the error correction and object detection, while also using flat planes as a basis for the mathematics. Two or more 3D scanning devices, such as scanning LIDARs, collect a 3D dataset for a field of view (FOV). The FOV is divided into boxes with a small degree of overlap, then each box is processed iteratively to identify features of an object contained within the box. Box size is chosen so that the portion of the object contained within the box can be assumed to be planar. Adjoining boxes are evaluated for shared data points then merged it the form part of the same object. |
| FILED | Saturday, February 15, 2020 |
| APPL NO | 17/431037 |
| CURRENT CPC | Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 17/89 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20220144669 | Shi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kentucky Research Foundation (Lexington, Kentucky) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jian Shi (Lexington, Kentucky); Wenqi Li (Lexington, Kentucky); Jameson Hunter (Lexington, Kentucky); Yuxuan Zhang (Lexington, Kentucky) |
| ABSTRACT | A method for synthesizing a hydrophobic deep eutectic solvent (DES) using one or more lignin-derived compounds is provided. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/521586 |
| CURRENT CPC | Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/26 (20130101) Original (OR) Class C02F 2101/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220146522 | Irudayaraj et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Joseph Irudayaraj (Champaign, Illinois); Wen Ren (Urbana, Illinois) |
| ABSTRACT | The present disclosure relates to a novel method for lateral flow immunoassay (LFIA) by utilizing plasmonic enhancement strategy. More specifically, the present disclosure provides a plasmonic enhanced lateral flow sensor (pLFS) concept by introducing a liposome-based amplification of the colorimetric signals on the lateral flow platform for ultrasensitive detection of pathogens. |
| FILED | Friday, October 15, 2021 |
| APPL NO | 17/502320 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/5023 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/521 (20130101) G01N 33/558 (20130101) G01N 33/586 (20130101) Original (OR) Class G01N 33/587 (20130101) G01N 33/56916 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220149526 | Hollar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wiser Systems, Inc. (Raleigh, North Carolina) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Seth Edward-Austin Hollar (Raleigh, North Carolina); Scott Francis Fisher (Raleigh, North Carolina) |
| ABSTRACT | Ultra-wideband (UWB) antennas are provided including a printed circuit board; a radiating element coupled to the printed circuit board and substantially perpendicular thereto; and radio frequency (RF) electronics associated with the antenna integrated with the printed circuit board. Related enclosures and systems are also provided. |
| FILED | Friday, January 21, 2022 |
| APPL NO | 17/580987 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 5/25 (20150115) H01Q 9/0464 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 20220144721 | Brogden et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Michael Brogden (Galloway, New Jersey); Steve Duffy (Hammonton, New Jersey) |
| ABSTRACT | An explosive sheet simulant that uses an ethylene vinyl acetate polymer combined with boron carbide or iron oxide for X-ray attenuating properties, and components of the mixture selected for predetermined flexural modulus combined with particle density, effective atomic number, X-ray transmission properties, or millimeter wave properties. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/583983 |
| CURRENT CPC | Explosives or Thermic Compositions; Manufacture Thereof; Use of Single Substances as Explosives C06B 23/001 (20130101) Original (OR) Class Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/38 (20130101) C08K 2003/265 (20130101) Compositions of Macromolecular Compounds C08L 23/0853 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220150711 | Lim et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Jason Lim (Alexandria, Virginia); Daniel Boyd (Arlington, Virginia); Chang Ellison (Arlington, Virginia); William Washington (North Potomac, Maryland) |
| ABSTRACT | A provider system is connected to readers disposed at distances from the provider system. A secure local connection is established between the client device and the provider system via one of the readers. Before the client reaches an access touchpoint, the provider system receives from the client device a request for client access, the provider system sends to the client device a request for identification information of the client, and the client device sends client information associated with a first mobile identification credential (MIC) which the client device received from an authorizing party system (APS), the client having consented to release the client information to the provider system, and the client information having been verified. The provider system uses the verified client information associated with the first MIC to verify or not verify the identity of the client before granting or denying the request to the client. |
| FILED | Tuesday, January 25, 2022 |
| APPL NO | 17/584223 |
| CURRENT CPC | Wireless Communication Networks H04W 12/06 (20130101) H04W 12/08 (20130101) H04W 12/71 (20210101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 20220143093 | BHATNAGAR et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Parijat BHATNAGAR (Belmont, California); Marvin A. SSEMADAALI (Menlo Park, California) |
| ABSTRACT | An example genetically engineered effector cell comprises an exogenous polynucleotide sequence that includes a receptor element, an actuator element, and an effector element. The receptor element encodes a chimeric antigen receptor (CAR) comprising an extracellular antigen binding domain operably linked to a transmembrane domain, and an intracellular signaling domain, wherein the extracellular antigen binding domain recognizes an antigen on a surface of a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)-infected cell. The actuator element encodes a transcription factor binding site that upregulates synthesis of an antiviral protein. The effector element encodes the antiviral protein operably linked to a signal peptide, wherein, in response to the antigen binding domain of the CAR binding to the antigen of SARS-CoV-2-infected cell, the engineered effector cell is configured to activate and, to synthesize and secrete the antiviral protein. |
| FILED | Thursday, January 27, 2022 |
| APPL NO | 17/586749 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/12 (20180101) Peptides C07K 14/7051 (20130101) C07K 16/2803 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220145037 | Nejati et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | NUtech Ventures (Lincoln, Nebraska) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Siamak Nejati (Lincoln, Nebraska); Mona Bavarian (Lincoln, Nebraska); Mahdi Mohammadi Ghaleni (Lincoln, Nebraska) |
| ABSTRACT | Provided here are compositions and methods for preparing porous omniphobic surfaces with desirable chemical and structural properties. The methods include sequential initiated chemical vapor deposition (iCVD) of low surface-energy materials onto a variety of substrates. |
| FILED | Friday, November 05, 2021 |
| APPL NO | 17/520611 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/60 (20130101) Working-up; General Processes of Compounding; After-treatment Not Covered by Subclasses C08B, C08C, C08F, C08G or C08H C08J 9/365 (20130101) Original (OR) Class C08J 2327/16 (20130101) C08J 2427/18 (20130101) C08J 2433/16 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/002 (20130101) C09D 127/18 (20130101) C09D 133/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Commerce (DOC)
| US 20220146597 | ELMQUIST et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNIVERSITY OF MARYLAND, COLLEGE PARK (College Park, Maryland); GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE, NATIONAL IN (Gaithersburg, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Randolph ELMQUIST (Gaithersburg, Maryland); Albert RIGOSI (Rockville, Maryland); Mattias KRUSKOPF (Washington Grove, Maryland) |
| ABSTRACT | A quantum Hall resistance apparatus is to improve resistance standards and includes a substrate, a graphene epitaxially grown on the substrate and having a plurality of first contact patterns at edges of the graphene, a plurality of contacts, each including a second contact pattern and configured to connect to a corresponding first contact pattern, and a protective layer configured to protect the graphene and to increase adherence between the first contact patterns and the second contact patterns. The contacts become a superconductor at a temperature lower than or equal to a predetermined temperature and under up to a predetermined magnetic flux density. |
| FILED | Wednesday, March 04, 2020 |
| APPL NO | 17/435807 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/07 (20130101) G01R 33/035 (20130101) G01R 33/0052 (20130101) Original (OR) Class Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 39/04 (20130101) H01L 39/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 20220143149 | Mirsaeidi et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Miami (Miami, Florida); The United States Government as Represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mehdi Mirsaeidi (Jacksonville, Florida); Chongxu Zhang (Riverside, Illinois); Andrew V. Schally (Miami Beach, Florida); Renzhi Cai (Miami, Florida) |
| ABSTRACT | The disclosure provides a method of treating sarcoidosis, the method comprising administering a GHRH antagonist to mammalian subject in need thereof. |
| FILED | Monday, January 17, 2022 |
| APPL NO | 17/648137 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/25 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 11/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Geospatial Intelligence Agency (NGA)
| US 20220148120 | Starr et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States of America, as represented by the Director, National Geospatial-Intelligence Agency (Springfield, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Director, National Geospatial-Intelligence Agency (Springfield, Virginia) |
| INVENTOR(S) | Michael A. Starr (Charlottesville, Virginia); Alexander J. Mulia (Crozet, Virginia) |
| ABSTRACT | Systems and methods for performing quality assurance assessments for unattended computer vision counting tools are presented. Classification information is used to generate coefficients for error equations. Recursive digital filters are used to train and update these coefficients. These coefficients are used to determine object count uncertainty ranges for an area of interest. |
| FILED | Monday, November 08, 2021 |
| APPL NO | 17/521056 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 1/0014 (20130101) Original (OR) Class G06T 7/70 (20170101) G06T 2207/30242 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 20220149841 | WHITELEY |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Synopsys, Inc. (Mountain View, California) |
| ASSIGNEE(S) | Synopsys, Inc. (Mountain View, California) |
| INVENTOR(S) | Stephen Robert WHITELEY (Sunnyvale, California) |
| ABSTRACT | Disclosed herein are embodiments including electrical structures that includes a first cell, a first inductor, a first resistor, and a first shunted Josephson junction. The first inductor is connected in series with the first shunted Josephson junction at a first terminal end of the first inductor and a second terminal end of the first inductor is connected to a feed point of the first cell being powered. A first end of the first resistor having connected to ground and a second end being connected to the first shunted Josephson junction at a terminal of the first shunted Josephson junction that is not connected to the first inductor. A source of an electrical current source that is external to the first cell is connected to the first shunted junction and the first resistor at a common point. |
| FILED | Thursday, March 12, 2020 |
| APPL NO | 17/438280 |
| CURRENT CPC | Electric Digital Data Processing G06F 30/367 (20200101) G06F 2119/06 (20200101) Pulse Technique H03K 19/0008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. Agency for International Development (USAID)
| US 20220142135 | ACHARYA et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Soumyadipta ACHARYA (Ellicott City, Maryland); Margaret GLANCEY (Baltimore, Maryland); Adam C. GOODWIN (Baltimore, Maryland); Laura Elizabeth Schiffrin SCAVO (Bethesda, Maryland); Jewell BREY (Chapel Hill, North Carolina); Tristan FORD (Baltimore, Maryland); Collyn J. HEIER (Cambridge, Massachusetts) |
| ABSTRACT | An insect trap analysis system may detect an insect specimen on a trap mechanism of an insect trap. The insect trap analysis system may control, based on detecting the insect specimen on the trap mechanism, one or more mechanical devices to: adjust a position of the insect specimen relative to a position of an image capture device associated with the insect trap, or adjust the position of the image capture device relative to the position of the insect specimen. The insect trap analysis system may cause, while controlling the one or more mechanical devices to adjust the position of the image capture device or the position of the insect specimen, the image capture device to capture a plurality of images of the insect specimen from a plurality of different angles relative to the insect specimen, and may perform an action associated with the plurality of images. |
| FILED | Wednesday, February 19, 2020 |
| APPL NO | 17/433138 |
| CURRENT CPC | Catching, Trapping or Scaring of Animals; Apparatus for the Destruction of Noxious Animals or Noxious Plants A01M 1/026 (20130101) Original (OR) Class Image or Video Recognition or Understanding G06V 20/52 (20220101) Pictorial Communication, e.g Television H04N 7/183 (20130101) Wireless Communication Networks H04W 4/029 (20180201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20220148056 | Dixon, JR. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert E. Dixon, JR. (Haymarket, Virginia) |
| ABSTRACT | Systems and methods described herein relate to a system for handling distribution items having identifiers thereon. Item processing equipment takes and stores an image of the physical distribution item and associates the identifier with the stored image. An offer can be associated with supplemental content that can be delivered to recipients of the physical distribution item and to other recipients who did not receive the physical distribution item. |
| FILED | Friday, November 05, 2021 |
| APPL NO | 17/453795 |
| CURRENT CPC | Electric Digital Data Processing G06F 16/23 (20190101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/0222 (20130101) G06Q 30/0611 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, May 12, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/details-applications-20220512.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
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