FedInvent™ Patent Applications
Application Details for Thursday, November 10, 2022
This page was updated on Thursday, November 10, 2022 at 05:46 PM GMT
Department of Health and Human Services (HHS)
| US 20220354108 | BROCKBANK et al. |
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| FUNDED BY |
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| APPLICANT(S) | TISSUE TESTING TECHNOLOGIES LLC (North Charleston, South Carolina) |
| ASSIGNEE(S) | TISSUE TESTING TECHNOLOGIES LLC (North Charleston, South Carolina) |
| INVENTOR(S) | Kelvin G.M. BROCKBANK (Charleston, South Carolina); Lia H. CAMPBELL (Mount Pleasant, South Carolina) |
| ABSTRACT | Cellular material containing living cells is preserved by combining the cellular material with a cryoprotectant formulation/medium/solution containing an effective amount of trehalose (in the absence of DMSO and/or any other added cryoprotectants) during a cryopreservation protocol. That is, the cryopreservation protocol is free of cryoprotectant other than trehalose, and the cryopreservation protocol includes: exposing the cellular material to a cryoprotectant formulation containing an effective amount of the trehalose to act as a cryoprotectant, cooling the cellular material at a cooling rate in the range of from −3° C./minute to −50° C./minute to a predetermined temperature below −20° C., and obtaining a cryopreserved cellular material that has been warmed. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 17/731616 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 1/0221 (20130101) Original (OR) Class A01N 1/0284 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354354 | Maiorano et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Children`s Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anthony Maiorano (Waltham, Massachusetts); Jeffrey C. Cerier (Franklin, Massachusetts) |
| ABSTRACT | In at least some aspects, an instrument port for introducing an instrument into a surgical site comprises: a port body having: an instrument channel extending through the port body; and a plurality of fluid flush channels each separate from one another and the instrument channel, each extending along a major portion of the port body and in fluid communication with the instrument channel; and a bulb comprising a bulb channel extending through the bulb, the bulb channel aligned with the instrument channel, wherein the bulb channel and instrument channel are configured to receive the instrument. |
| FILED | Monday, March 28, 2022 |
| APPL NO | 17/706279 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/015 (20130101) A61B 1/018 (20130101) A61B 1/00066 (20130101) A61B 1/00094 (20130101) A61B 1/00096 (20130101) A61B 1/00101 (20130101) A61B 1/00119 (20130101) A61B 1/125 (20130101) A61B 1/126 (20130101) Original (OR) Class A61B 1/00128 (20130101) A61B 17/3415 (20130101) A61B 17/3421 (20130101) A61B 17/3498 (20130101) A61B 2017/00243 (20130101) A61B 2017/3445 (20130101) A61B 2217/005 (20130101) A61B 2217/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354425 | Meaney et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| ASSIGNEE(S) | Trustees of Dartmouth College (Hanover, New Hampshire) |
| INVENTOR(S) | Paul Meaney (Hanover, New Hampshire); Timothy Raynolds (Lebanon, New Hampshire); Robin Augustine (Uppsala, Sweden) |
| ABSTRACT | Embodiments of the present disclosure pertain to transmission dielectric probes with at least one channel that extends across the probe. The channel includes a first opening on a first side of the transmission dielectric probe, and a second opening on a second side of the transmission dielectric probe. The first opening and the second opening are on opposite ends of the transmission dielectric probe, and the second opening is associated with an outer surface of the transmission dielectric probe. Additionally, the first opening and the second opening have different diameters, different geometries, or combinations thereof. Further embodiments pertain to methods of operating the transmission dielectric probes by placing the outer surface of the transmission dielectric probe on a surface of an object, transmitting a signal from a first channel through the surface and into the object, and receiving the transmitted signal back through a second channel. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/766121 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/4869 (20130101) Original (OR) Class A61B 18/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354573 | Yang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | Trustees of Boston University (Boston, Massachusetts) |
| INVENTOR(S) | Chen Yang (Newton, Massachusetts); Ji-Xin Cheng (Newton, Massachusetts); Nan Zheng (Allston, Massachusetts); Yueming Li (Brighton, Massachusetts); Ying Jiang (Brighton, Massachusetts); Lu Lan (Allston, Massachusetts); Carolyn Marar (Brighton, Massachusetts) |
| ABSTRACT | A system for neuromodulation includes a split-ring resonator (SRR) comprising a resonance circuit, the SRR being implantable in a cranial target site and a source of microwave signals, wherein the microwave signals are deliverable wirelessly to couple with the SRR to produce a localized electrical field, wherein the localized electrical field inhibits one or more neurons at the cranial target site with submillimeter spatial precision. |
| FILED | Thursday, May 05, 2022 |
| APPL NO | 17/737710 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 18/1815 (20130101) Original (OR) Class A61B 2018/183 (20130101) A61B 2018/1869 (20130101) Waveguides; Resonators, Lines, or Other Devices of the Waveguide Type H01P 7/082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354603 | Hasser et al. |
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| FUNDED BY |
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| APPLICANT(S) | INTUITIVE SURGICAL OPERATIONS, INC. (Sunnyvale, California); The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher J. Hasser (Los Altos, California); Russell H. Taylor (Severna Park, Maryland); Joshua Leven (San Francisco, California); Michael Choti (Lutherville, Maryland) |
| ABSTRACT | A LUS robotic surgical system is trainable by a surgeon to automatically move a LUS probe in a desired fashion upon command so that the surgeon does not have to do so manually during a minimally invasive surgical procedure. A sequence of 2D ultrasound image slices captured by the LUS probe according to stored instructions are processable into a 3D ultrasound computer model of an anatomic structure, which may be displayed as a 3D or 2D overlay to a camera view or in a PIP as selected by the surgeon or programmed to assist the surgeon in inspecting an anatomic structure for abnormalities. Virtual fixtures are definable so as to assist the surgeon in accurately guiding a tool to a target on the displayed ultrasound image. |
| FILED | Monday, July 11, 2022 |
| APPL NO | 17/861530 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 1/3132 (20130101) A61B 8/12 (20130101) A61B 8/461 (20130101) A61B 8/4218 (20130101) A61B 8/4245 (20130101) A61B 34/25 (20160201) A61B 34/30 (20160201) A61B 34/37 (20160201) Original (OR) Class A61B 34/70 (20160201) A61B 34/76 (20160201) A61B 90/37 (20160201) A61B 90/361 (20160201) A61B 2034/107 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354633 | SALES et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cornell University (Ithaca, NY, None) |
| ASSIGNEE(S) | Cornell University (Ithaca, NY, None) |
| INVENTOR(S) | Christopher SALES (New York, New York); David PUTNAM (New York, New York) |
| ABSTRACT | The present solution can temporarily impart the handling characteristics of corneal stroma to the otherwise very thin, flimsy, coiling, and fragile Descemet membrane endothelial keratoplasty (DMEK) tissue during its insertion into the anterior chamber and positioning in apposition against the cornea of the recipient eye. The device of the present solution can be configured in a number of ways. In a first configuration, a scaffold can be coupled with the endothelial side of the DMEK graft. In a second configuration, the scaffold can be coupled with the stromal side of the DMEK graft. In a third configuration, one or more scaffolds can be coupled with both the endothelial and stromal side of the DMEK graft. |
| FILED | Wednesday, May 06, 2020 |
| APPL NO | 17/609231 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/142 (20130101) Original (OR) Class A61F 2210/0076 (20130101) A61F 2250/0031 (20130101) A61F 2250/0059 (20130101) Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/18 (20130101) A61L 27/20 (20130101) A61L 27/26 (20130101) A61L 27/58 (20130101) A61L 27/3604 (20130101) A61L 27/3666 (20130101) A61L 2430/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354827 | Wei et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Huafeng Wei (Cherry Hill, New Jersey); Qing Cheng Meng (Ardmore, Pennsylvania); Ge Liang (Wynnewood, Pennsylvania); Maryellen Fazen Eckenhoff (Philadelphia, Pennsylvania) |
| ABSTRACT | Methods for inhibiting impaired neurogenesis and/or synaptogenesis in neurons in a subject with or suspected of having Alzheimer's Disease (AD), methods for improving and/or slowing the decline of cognitive function after onset of neuropathology and cognitive dysfunction, which neuropathology and cognitive dysfunction are caused by AD, methods for improving and/or slowing the decline of memory before onset of symptoms of AD, methods for increasing concentration and duration of dantrolene in the brain, and methods for improving and/or slowing the decline of memory after onset of symptoms of AD, the methods comprising intranasally administering to a subject in need thereof an amount of a pharmaceutical composition comprising dantrolene effective to inhibit over-activation of N-methyl-D-aspartate (NMVDA) receptor and/or ryanodine receptor (RyR). Methods further comprise administering a therapeutically effective amount of a glutamate receptor antagonist to the subject. |
| FILED | Monday, June 29, 2020 |
| APPL NO | 17/623246 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 31/4178 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/28 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354833 | PARKIN et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEREO BIOPHARMA 4 LIMITED (London, United Kingdom); DUKE UNIVERSITY (Durham, North Carolina); NATIONAL CANCER INSTITUTE (Bethesda, Maryland) |
| ASSIGNEE(S) | MEREO BIOPHARMA 4 LIMITED (London, United Kingdom); DUKE UNIVERSITY (Durham, North Carolina); NATIONAL CANCER INSTITUTE (Bethesda, Maryland) |
| INVENTOR(S) | Jacqueline PARKIN (London, United Kingdom); Anthony SUNG (Durham, North Carolina); Steven Z. PAVLETIC (Bethesda, Maryland); Annie IM (Pittsburgh, Pennsylvania); Noa G. HOLTZMAN (Bethesda, Maryland); Cody J. PEER (Bethesda, Maryland) |
| ABSTRACT | The invention relates to treatments for organ rejection, in particular to treatments for lung transplant associated bronchiolitis obliterans syndrome by administering a neutrophil elastase inhibitor, such as alvelestat. The invention also relates to treatments for graft versus host disease. |
| FILED | Thursday, September 17, 2020 |
| APPL NO | 17/753706 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/444 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 37/06 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354838 | John et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| ASSIGNEE(S) | The Jackson Laboratory (Bar Harbor, Maine) |
| INVENTOR(S) | Simon W. M. John (Bar Harbor, Maine); Peter Alexander Williams (Bar Harbor, Maine) |
| ABSTRACT | The invention relates to the use of a pharmaceutical composition containing nicotinamide (NAM) and/or pyruvate as a neuroprotective medicament or gene therapy in the treatment of neurodegenerative disorders, in particular axon degeneration of neuronal tissue in ocular-related neurodegeneration diseases including glaucoma. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/862668 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/19 (20130101) A61K 31/455 (20130101) Original (OR) Class A61K 31/706 (20130101) A61K 31/4745 (20130101) A61K 38/00 (20130101) A61K 38/45 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 48/005 (20130101) A61K 48/0075 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/06 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14143 (20130101) Enzymes C12Y 207/07001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354845 | Calabretta et al. |
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| FUNDED BY |
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| APPLICANT(S) | Thomas Jefferson University (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bruno Calabretta (Philadelphia, Pennsylvania); Alexander Mazo (Cherry Hill, New Jersey); Svetlana Petruk (Voorhees, New Jersey); Patrizia Porazzi (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention relates to methods of treating cancer in a subject in need thereof by treatments which enhance DNA damage and apoptosis of leukemic cells. |
| FILED | Friday, August 21, 2020 |
| APPL NO | 17/637004 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/497 (20130101) Original (OR) Class A61K 31/7068 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/02 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354855 | Kashyap et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Purna C. Kashyap (Rochester, Minnesota); Ruben Albertus Teunis Mars (Rochester, Minnesota) |
| ABSTRACT | Materials and methods for treating irritable bowel syndrome (IBS) are provided herein. For example, materials and methods for increasing the level of hypoxanthine in a mammal identified as having IBS are provided herein |
| FILED | Friday, October 09, 2020 |
| APPL NO | 17/762895 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/522 (20130101) Original (OR) Class A61K 35/742 (20130101) A61K 35/745 (20130101) A61K 35/747 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354861 | ROTOLO et al. |
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| APPLICANT(S) | Sloan Kettering Institute for Cancer Research (New York, New York); Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jimmy Andrew ROTOLO (Port Washington, New York); Richard N. KOLESNICK (New York, New York); Renata PASQUALINI (Los Ranchos de Albuquerque, New Mexico); Wadih ARAP (Los Ranchos de Albuquerque, New Mexico) |
| ABSTRACT | We have discovered that administering anti-ceramide antibody treats and prevents an array of diseases mediated by cytolytic T lymphocyte (CTLs)-induced killing and by damage to endothelial microvasculture, including radiation-induced GI syndrome, Graft vs. Host diseases, inflammatory diseases and autoimmune diseases. We have also discovered new anti-ceramide monoclonal antibodies, that have therapeutic use preferably in humanized form to treat or prevent these diseases. |
| FILED | Tuesday, November 30, 2021 |
| APPL NO | 17/537786 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/55 (20130101) Original (OR) Class A61K 2039/505 (20130101) Peptides C07K 16/28 (20130101) C07K 16/40 (20130101) C07K 16/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354891 | WANG et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yingxiao WANG (San Diego, California); Praopim LIMSAKUL (San Diego, California); Yiqian WU (San Diego, California) |
| ABSTRACT | In alternative embodiments, provided are compositions, including products of manufacture and kits, and methods, for engineering immune effector cells, e.g., T cells, NK cells, monocytes and/or macrophages to recognize and destroy a desired target cell, which can be a cancer cell, a dysfunctional cell, or an infected cell. |
| FILED | Thursday, July 16, 2020 |
| APPL NO | 17/627193 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/195 (20130101) A61K 47/6803 (20170801) Peptides C07K 16/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354893 | Garcia et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD UNIVERSITY (STANFORD, California); UNIVERSITY OF WASHINGTON (SEATTLE, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kenan Christopher Garcia (Menlo Park, California); Jonathan Sockolosky (San Francisco, California); David Baker (Seattle, Washington); Chris King (Seattle, Washington) |
| ABSTRACT | Engineered orthogonal cytokine receptor/ligand pairs, and methods of use thereof, are provided. |
| FILED | Tuesday, July 26, 2022 |
| APPL NO | 17/815092 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/1793 (20130101) A61K 38/2013 (20130101) A61K 2039/5156 (20130101) Peptides C07K 14/55 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0638 (20130101) C12N 15/1034 (20130101) C12N 2740/10043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354896 | NASONKIN et al. |
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| APPLICANT(S) | LINEAGE CELL THERAPEUTICS, INC. (Carlsbad, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Igor NASONKIN (Carlsbad, California); Ratnesh SINGH (Carlsbad, California); Francois BINETTE (Carlsbad, California) |
| ABSTRACT | Presented herein are compositions and methods for generating stem cell derived retinal tissue and isolated retinal progenitor cells for use in the treatment of retinal degenerative diseases and disorders. |
| FILED | Tuesday, April 28, 2020 |
| APPL NO | 17/606990 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/30 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354897 | GUTOVA et al. |
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| FUNDED BY |
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| APPLICANT(S) | CITY OF HOPE (Duarte, California); UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | CITY OF HOPE (Duarte, California); UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Margarita GUTOVA (Duarte, California); Anthony KLINE (Pittsburgh, Pennsylvania) |
| ABSTRACT | This disclosure relates to methods for treating a subject having a traumatic brain injury (TBI) by intranasal administration of neural stem cells (NSCs), while optionally providing environmental enrichment (EE) to the subject in conjunction with or in combination with the NSC administration. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/662627 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 35/30 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354905 | Aroian et al. |
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| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raffi Van Aroian (Worcester, Massachusetts); Gary R. Ostroff (Worcester, Massachusetts) |
| ABSTRACT | Compositions and methods for treating or reducing the severity of occurrence of a parasitic worm or helminth infection in a subject are described. The methods include administering to the subject a therapeutically effective amount of a composition comprising isolated native, bioactive nematicidal crystals formed from a single type of nematicidal crystal protein. The isolated native, bioactive nematicidal crystals are substantially free of any bacterial spores or host bacterial proteins, other than nematicidal crystal protein in the form of a crystal. Methods for making isolated native, bioactive nematicidal crystals are also described. The crystal proteins may be full length, truncated, variant, or sub-variant Cry proteins. Examples of crystal proteins include Cry5B, Cry21, Cry14A, Cry6A, and Cry13A. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 17/729785 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/48 (20130101) A61K 35/741 (20130101) Original (OR) Class A61K 38/164 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354935 | IBRAHIM et al. |
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| FUNDED BY |
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| APPLICANT(S) | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center (Torrance, California); The University of Utah (Salt Lake City, Utah) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ashraf S. IBRAHIM (Torrance, California); June L. ROUND (Salt Lake City, Utah); Kyla OST (Salt Lake City, Utah) |
| ABSTRACT | The invention provides a vaccine against inflammatory bowel disease (IBD), such as Crohn's disease, ulcerative colitis, and the like. The vaccine comprises a polypeptide comprising a Candida adhesin antigen, typically an isolated agglutinin-like sequence (Als) protein antigen, formulated with one or more pharmaceutically acceptable carriers or excipients. |
| FILED | Thursday, April 21, 2022 |
| APPL NO | 17/726481 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0073 (20130101) A61K 39/0002 (20130101) Original (OR) Class A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 1/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354942 | Kaiser et al. |
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| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jaclyn Kaiser (Galveston, Texas); Tian Wang (Galveston, Texas); Alan Barrett (Galveston, Texas); Kassandra Carpio (Galveston, Texas) |
| ABSTRACT | Aspects of the disclosure relate to attenuated flaviviruses for use in vaccines and immunogenic compositions. Embodiments include methods for treating or preventing one or more conditions, for example flavivirus infection, using an attenuated flavivirus. In some embodiments, the disclosed methods and compositions involve one or more attenuated flaviviruses that are capable of inducing a protective immune response. |
| FILED | Thursday, May 05, 2022 |
| APPL NO | 17/737991 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) Original (OR) Class A61K 2039/5254 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 14/18 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354943 | Krishnan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Altimmune, Inc (Gaithersburg, Maryland) |
| ASSIGNEE(S) | Altimmune, Inc (Gaithersburg, Maryland) |
| INVENTOR(S) | Vyjayanthi Krishnan (Gaithersburg, Maryland); M. Scot Roberts (Gaithersburg, Maryland) |
| ABSTRACT | Disclosed herein are methods for generating a protective immunogenic response via intranasal administration of an immunogenic composition (e.g., vaccine)/therapeutic immunogenic composition in a mammalian subject. Certain dosing positions of the subject during the administration of immunogenic agents, such that nostrils are tilted upwards, while in a modified sitting, reclining and/or supine posture, is surprisingly correlated with the generation of a strong immunogenic response in both humans and animals. |
| FILED | Thursday, August 13, 2020 |
| APPL NO | 17/634990 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0043 (20130101) A61K 39/0002 (20130101) A61K 39/04 (20130101) A61K 39/07 (20130101) A61K 39/12 (20130101) A61K 39/085 (20130101) A61K 39/092 (20130101) A61K 39/102 (20130101) A61K 39/104 (20130101) A61K 39/125 (20130101) A61K 39/145 (20130101) Original (OR) Class A61K 39/165 (20130101) A61K 39/215 (20130101) A61K 39/0241 (20130101) A61K 39/0266 (20130101) A61K 2039/543 (20130101) A61K 2039/545 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) A61P 31/16 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354962 | TSOURKAS et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Andrew TSOURKAS (Bryn Mawr, Pennsylvania); Linghan Mei (Urumqi, China PRC); Fabiana Zappala (Philadelphia, Pennsylvania) |
| ABSTRACT | The invention relates to antibody conjugates (e.g., a bispecific antibody), drug and nanoparticle compositions and methods and compositions for generating them. This invention further relates to methods of using these compositions to image, diagnose or treat a disease. |
| FILED | Monday, November 22, 2021 |
| APPL NO | 17/533071 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6851 (20170801) A61K 47/6889 (20170801) Original (OR) Class A61K 2039/572 (20130101) Peptides C07K 14/315 (20130101) C07K 16/468 (20130101) C07K 16/2803 (20130101) C07K 16/2809 (20130101) C07K 16/2887 (20130101) C07K 2317/31 (20130101) C07K 2317/52 (20130101) C07K 2317/622 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/48 (20130101) C12N 15/62 (20130101) Enzymes C12Y 304/2207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354969 | Nakai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon) |
| INVENTOR(S) | Hiroyuki Nakai (West Linn, Oregon); Masahiro Horikawa (Portland, Oregon); Kei Adachi (Beaverton, Oregon) |
| ABSTRACT | Disclosed herein are methods for delivering a composition comprising an adeno-associated virus (AAV) to one or more pancreatic cells in a subject. Also disclosed are adeno-associated viral vectors for use in these methods. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/740240 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0075 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2750/14143 (20130101) C12N 2750/14171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354974 | Wilbur et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | D. Scott Wilbur (Seattle, Washington); Ming-Kuan Chyan (Seattle, Washington); Donald K. Hamlin (Seattle, Washington) |
| ABSTRACT | Reagents and methods for labeling biomolecules with astatine isotopes in higher oxidation states. The reagents and methods allow for efficient labeling of biomolecules, such as antibodies, without the formation of high molecular weight by products that arise due to 211At-promoted dimerization and higher aggregation of the conjugated biomolecules, and diminish cellular retention of astatine caused by cellular oxidization of the bonded astatine atom in vivo. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 17/730130 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/10 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354994 | Bhatia et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Sangeeta N. Bhatia (Lexington, Massachusetts); Kelly R. Stevens (Cambridge, Massachusetts); Christopher S. Chen (Newton, Massachusetts) |
| ABSTRACT | Engineered human tissue seed constructs are provided that are suitable for implantation in subjects. Methods of making and using the engineered tissue seed constructs are provided. |
| FILED | Friday, April 22, 2022 |
| APPL NO | 17/727293 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 27/52 (20130101) Original (OR) Class A61L 27/225 (20130101) A61L 27/3804 (20130101) A61L 27/3808 (20130101) A61L 27/3886 (20130101) A61L 27/3891 (20130101) A61L 2430/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354998 | Tamayol et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Connecticut (Farmington, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ali Tamayol (Farmington, Connecticut); Lindsay Barnum (Farmington, Connecticut) |
| ABSTRACT | Disclosed herein are drug delivery devices that can temporally and spatially deliver biologically active agents. An example drug delivery device includes a microneedle array comprising a plurality of microneedles on a surface of a substrate, each microneedle comprising a core comprising a hydrogel and a layer on a surface of the core. Also disclosed are methods of using the drug delivery device, and methods of making the microneedle array that includes a loading device. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738936 |
| CURRENT CPC | Methods or Apparatus for Sterilising Materials or Objects in General; Disinfection, Sterilisation, or Deodorisation of Air; Chemical Aspects of Bandages, Dressings, Absorbent Pads, or Surgical Articles; Materials for Bandages, Dressings, Absorbent Pads, or Surgical Articles A61L 31/16 (20130101) A61L 31/048 (20130101) A61L 31/145 (20130101) Original (OR) Class A61L 31/146 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 37/0015 (20130101) A61M 2037/0023 (20130101) A61M 2037/0046 (20130101) A61M 2037/0053 (20130101) A61M 2037/0061 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/35 (20170801) Indexing Scheme Associated With Subclass B29C, Relating to Particular Articles B29L 2031/7544 (20130101) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 40/20 (20200101) B33Y 80/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355111 | Kilgard |
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| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Michael P. Kilgard (Richardson, Texas) |
| ABSTRACT | Provided is an effective stereognosis training system that integrates hardware and software to provide a simple, reliable, quantitative system to provide tactile rehabilitation and progress monitoring. The system can include an interactive device including a novel set of objects, that are combined with neuromodulatory systems such as wireless closed-loop vagus nerve stimulation to improve neural plasticity and expedite functional recovery. The system can send updates to therapists or clinicians to monitor progress and encourage compliance with prescribed therapy. |
| FILED | Monday, May 30, 2022 |
| APPL NO | 17/804576 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/1128 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/36053 (20130101) A61N 1/36103 (20130101) Original (OR) Class A61N 1/36139 (20130101) A61N 1/37211 (20130101) Educational or Demonstration Appliances; Appliances for Teaching, or Communicating With, the Blind, Deaf or Mute; Models; Planetaria; Globes; Maps; Diagrams G09B 19/003 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355273 | Beebe et al. |
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| FUNDED BY |
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| APPLICANT(S) | Salus Discovery, LLC (Madison, Wisconsin); Flambeau Diagnostics, LLC (Monona, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dave Beebe (Monona, Wisconsin); Patrick McMinn (Madison, Wisconsin); Brianna Mullins (Deforest, Wisconsin); Jay Warrick (Madison, Wisconsin) |
| ABSTRACT | Stabilized interface systems and compositions for positioning target(s), comprising fluids, associated structural material(s) having a pore that permits passage and positioning of targets and related compositions, and a fluid phase, layer, or interface stabilized with the associated structural material. Miscible interface systems and compositions for positioning target(s) for detection comprising two or more fluid regions with different properties within a phase or layer where the fluid regions are stabilized with respect to each other using a solid or semi-solid structure or material with at least one pore that allows passage of said target(s) wherein stabilization allows mass transport of a fluid constituent via diffusion to prevail over bulk fluid motion. |
| FILED | Thursday, May 05, 2022 |
| APPL NO | 17/737808 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/103 (20130101) B01J 20/28042 (20130101) Original (OR) Class B01J 20/28069 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355289 | Shtein et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Max Shtein (Ann Arbor, Michigan); Y. Eugene Shteyn (Cupertino, California); Steven Morris (Ann Arbor, Michigan); Brian lezzi (Ann Arbor, Michigan); Siddharth Borsadia (Ann Arbor, Michigan); Joanna Ciatti (Ann Arbor, Michigan); Katie Wei (Ann Arbor, Michigan) |
| ABSTRACT | Disclosed herein is are methods and apparatuses for synthesizing deposited films of compounds (e.g., organic compounds such as a pharmaceutical active ingredient or a new chemical entity) on or in a variety of substrates, where such deposited compounds the desired stability under storage conditions, ease of handling, and yet enhanced dissolution properties when used in various assays. The disclosure further relates to methods of coating substrates, such as medical or diagnostic devices, with deposited films of organic compounds, as well as film-coated substrates. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 17/604919 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/52 (20130101) B01L 3/0289 (20130101) Original (OR) Class B01L 3/5085 (20130101) B01L 2200/16 (20130101) B01L 2200/141 (20130101) B01L 2200/148 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/60 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355297 | Burns et al. |
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| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark A. Burns (Ann Arbor, Michigan); Alyse D. Krausz (Ann Arbor, Michigan); Sarah Elizabeth Mena (Ann Arbor, Michigan); Martin Patrick De Beer (Ann Arbor, Michigan); Kevin R. Ward (Superio Township, Michigan); Frederick Korley (Ann Arbor, Michigan) |
| ABSTRACT | A microfluidic device system includes a channel having an entrance and an exit, a height at the entrance being greater than a height at the exit. The height of the channel may decrease continuously from the height at the entrance to the height at the exit. Cells or particles or beads traveling through the channel become trapped based on their size and/or deformability. A visual sensor captures images of the trapped cells or particles or beads, and image software analyzes the captured images to provide size and/or deformability and/or fluorescence information. A method of fabricating such a microfluidic device includes introducing a glass wafer to an etching solution at a specific rate such that a first end of the glass wafer is etched longer than other portions of the glass wafer. |
| FILED | Monday, July 18, 2022 |
| APPL NO | 17/813313 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502707 (20130101) B01L 3/502715 (20130101) B01L 3/502761 (20130101) Original (OR) Class B01L 2200/12 (20130101) B01L 2200/0668 (20130101) B01L 2300/0627 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/28 (20130101) G01N 15/1475 (20130101) G01N 21/6428 (20130101) G01N 33/6803 (20130101) G01N 33/54366 (20130101) G01N 2015/1493 (20130101) G01N 2021/6439 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356139 | Wang |
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| FUNDED BY |
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| APPLICANT(S) | ARIZONA BOARD OF REGENTS ON BEHALF OF ATHE UNIVERSITY OF ARIZONA (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wei Wang (Tucson, Arizona) |
| ABSTRACT | Described are methods for preparing a deuterated aldehyde using N-heterocyclic carbene catalysts in a solvent comprising D2O. The methods may be used to convert a wide variety of aldehydes (e.g., aryl, alkyl, or alkenyl aldehydes) to C-1 deuterated aldehydes under mild reaction conditions without functionality manipulation. |
| FILED | Wednesday, August 12, 2020 |
| APPL NO | 17/639750 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 31/2273 (20130101) General Methods of Organic Chemistry; Apparatus Therefor C07B 59/001 (20130101) C07B 2200/05 (20130101) Acyclic or Carbocyclic Compounds C07C 45/50 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356147 | Melander et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | University of Notre Dame du Lac (South Bend, Indiana) |
| INVENTOR(S) | Christian Melander (South Bend, Indiana); Alexander WEIG (South Bend, Indiana); Akash Kumar BASAK (South Bend, Indiana) |
| ABSTRACT | Infections caused by multidrug-resistant (MDR) bacteria, particularly Gram-negative bacteria, are an escalating global t health threat. Often clinicians are forced to administer the last resort antibiotic colistin, however colistin resistance is becoming increasingly prevalent, giving rise to the potential for a situation in which there are no treatment options for MDR Gram-negative infections. The development of adjuvants that circumvent bacterial resistance mechanisms is a promising orthogonal approach to the development of new antibiotics. We recently disclosed that the known IKK-13 inhibitor IMD-0354 potently suppresses colistin resistance in several Gram-negative strains. In this disclosure, we explore the structure activity relationship (SAR) between the IMD-0354 scaffold and colistin resistance suppression, and identify several compounds with more potent activity than the parent against highly colistin resistant strains of Acinetobacter baumannii and Klebsiella pneumoniae. |
| FILED | Thursday, October 08, 2020 |
| APPL NO | 17/771896 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Acyclic or Carbocyclic Compounds C07C 235/64 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356153 | RISHTON et al. |
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| FUNDED BY |
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| APPLICANT(S) | COGNITION THERAPEUTICS, INC. (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | COGNITION THERAPEUTICS, INC. (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Gilbert M. RISHTON (Los Angeles, California); Gary C. LOOK (Santa Clara, California); Susan M. CATALANO (Pittsburgh, Pennsylvania) |
| ABSTRACT | The present disclosure relates to novel compounds, pharmaceutical compositions containing the compounds and methods of using the compounds and pharmaceutical compositions for treating neurodegerative diseases, including Alzheimer's disease and cognitive decline. Methods for inhibiting synapse number decline or membrane trafficking abnormalities associated with exposure of a neuronal cell to Abeta species are also disclosed. |
| FILED | Monday, November 29, 2021 |
| APPL NO | 17/537110 |
| CURRENT CPC | Heterocyclic Compounds C07D 205/04 (20130101) Original (OR) Class C07D 207/08 (20130101) C07D 207/16 (20130101) C07D 211/22 (20130101) C07D 211/46 (20130101) C07D 211/48 (20130101) C07D 241/04 (20130101) C07D 241/08 (20130101) C07D 265/30 (20130101) C07D 401/04 (20130101) C07D 403/06 (20130101) C07D 403/14 (20130101) C07D 405/04 (20130101) C07D 405/12 (20130101) C07D 413/14 (20130101) C07D 491/107 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356157 | MEDINA et al. |
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| FUNDED BY |
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| APPLICANT(S) | Epiodyne, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Julio Cesar MEDINA (South San Francisco, California); Alok NERURKAR (San Diego, California); Corinne SADLOWSKI (London, United Kingdom); Frederick SEIDL (San Mateo, California); Heng CHENG (Fremont, California); Jason DUQUETTE (Millbrae, California); John LEE (Pacifica, California); Martin HOLAN (Stamford, Connecticut); Pingyu DING (Foster City, California); Xiaodong WANG (South San Francisco, California); Tien WIDJAJA (Lafayette, Colorado); Thomas NGUYEN (Newbury Park, California); Ulhas BHATT (Fremont, California); Yihong LI (South San Francisco, California); Zhi-liang WEI (Foster City, California) |
| ABSTRACT | Provided herein are opioid receptor modulators and pharmaceutical compositions comprising said compounds. |
| FILED | Tuesday, April 05, 2022 |
| APPL NO | 17/714030 |
| CURRENT CPC | Acyclic or Carbocyclic Compounds C07C 233/65 (20130101) Heterocyclic Compounds C07D 213/56 (20130101) C07D 239/26 (20130101) C07D 263/58 (20130101) C07D 277/30 (20130101) Original (OR) Class C07D 295/155 (20130101) C07D 307/54 (20130101) C07D 333/24 (20130101) C07D 401/12 (20130101) C07D 413/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356163 | BENEZRA et al. |
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| FUNDED BY |
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| APPLICANT(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| ASSIGNEE(S) | MEMORIAL SLOAN KETTERING CANCER CENTER (New York, New York) |
| INVENTOR(S) | Robert BENEZRA (New York, New York); Ouathek OUERFELLI (New York, New York); Guangli YANG (New York, New York) |
| ABSTRACT | The present technology relates generally to compounds, compositions, and methods useful for treating, preventing, and/or ameliorating pathogenic cellular proliferation, angiogenesis, cancer, metastatic disease, and/or a pathogenic vascular proliferative disease in a subject. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/766027 |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Acyclic or Carbocyclic Compounds C07C 211/49 (20130101) C07C 217/60 (20130101) C07C 217/62 (20130101) Heterocyclic Compounds C07D 317/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356176 | Calcaterra et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland); Lieber Institute, Inc. (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nicholas E. Calcaterra (Baltimore, Maryland); Yifang Huang (Baltimore, Maryland); Pablo DeLeon (Baltimore, Maryland); James Barrow (Baltimore, Maryland) |
| ABSTRACT | Compounds of formula (I), formula (II), or formula (III) and their use with a neurological or psychiatric disorder, mediated by Kv11.1-3.1 containing potassium channels, including schizophrenia, are disclosed. |
| FILED | Thursday, June 11, 2020 |
| APPL NO | 17/617743 |
| CURRENT CPC | Heterocyclic Compounds C07D 401/04 (20130101) C07D 401/12 (20130101) C07D 401/14 (20130101) C07D 403/12 (20130101) C07D 413/12 (20130101) Original (OR) Class C07D 471/08 (20130101) C07D 487/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356207 | ENDO et al. |
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| FUNDED BY |
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| APPLICANT(S) | Astellas Pharma Inc. (Tokyo, Japan); National Center for Global Health and Medicine (Tokyo, Japan); Hiroshima University (Higashihiroshima-shi, Japan) |
| ASSIGNEE(S) | Astellas Pharma Inc. (Tokyo, Japan); National Center for Global Health and Medicine (Tokyo, Japan); Hiroshima University (Higashihiroshima-shi, Japan) |
| INVENTOR(S) | Hideki ENDO (Tokyo, Japan); Yukihito ISHIZAKA (Tokyo, Japan); Akira ISHIGURO (Tokyo, Japan); Tomoki TAKASHINA (Tokyo, Japan); Takashi YAMAMOTO (Hiroshima, Japan); Tetsushi SAKUMA (Hiroshima, Japan) |
| ABSTRACT | An object of the present invention is to provide a cell penetrating peptide having a penetrating ability into cells. The present inventors provided a cell penetrating peptide consisting of the amino acid sequence of SEQ ID NO: 1, a cell penetrating peptide consisting of the amino acid sequence of SEQ ID NO: 2 and a cell penetrating peptide consisting of the amino acid sequence of SEQ ID NO: 3; and a complex comprising any one of the cell penetrating peptide and a functional molecule. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/854647 |
| CURRENT CPC | Peptides C07K 7/06 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356217 | Arnaout |
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| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | M. Amin Arnaout (Chestnut Hill, Massachusetts) |
| ABSTRACT | The present application relates to polypeptides which are integrin antagonists. Methods of preparing the integrin antagonists and methods of treating diseases and disorders associated with abnormal levels and/or expression of one or more integrins are also provided. |
| FILED | Thursday, August 08, 2019 |
| APPL NO | 17/266339 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/4703 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356218 | Dewji et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Nazneen Dewji (San Diego, California); S. Jonathan Singer (La Jolla, California) |
| ABSTRACT | The disclosure relates generally to neurodegenerative disorders and more specifically to a group of presenilin/G-protein/c-src binding polypeptides and methods of use for modulating signaling and progression of Alzheimer's disease. |
| FILED | Tuesday, December 14, 2021 |
| APPL NO | 17/550306 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) A61K 38/08 (20130101) A61K 38/10 (20130101) A61K 38/1709 (20130101) Peptides C07K 7/06 (20130101) C07K 7/08 (20130101) C07K 14/4711 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356225 | ROYBAL et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kole T. ROYBAL (San Francisco, California); Iowis ZHU (San Francisco, California); Raymond LIU (San Francisco, California); Ahmad S. KHALIL (Boston, Massachusetts); Divya ISRANI (Boston, Massachusetts) |
| ABSTRACT | The present disclosure generally relates to, inter alia, a new class of chimeric Notch receptors containing a synthetic zinc finger transcriptional effector (synZTE) module, engineered to modulate gene expression and cellular activities in a ligand-dependent manner. The new Notch receptors surprisingly retain the ability to transduce signals in response to ligand binding despite that the Notch extracellular subunit, which includes the negative regulatory region previously believed to be essential for the functioning of Notch receptors, is partly or completely deleted. In addition, the synZTE is designed to bind orthogonal DNA target sequences in target organisms which in turn facilitates precise regulation of therapeutic gene expression with minimal off-target activity. Also provided are compositions and methods useful for producing such receptors, nucleic acids encoding same, host cells genetically modified with the nucleic acids, as well as methods for modulating an activity of a cell and/or for treatment of various health conditions. |
| FILED | Wednesday, September 23, 2020 |
| APPL NO | 17/763122 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/2803 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356229 | WESTENDORF et al. |
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| FUNDED BY |
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| APPLICANT(S) | AbCellera Biologics Inc. (Vancouver, Canada); The United States of America, as represented by the Secretary, Department of Health and Human Svcs. (Bethesda, Maryland) |
| ASSIGNEE(S) | AbCellera Biologics Inc. (Vancouver, Canada); The United States of America, as represented by the Secretary, Department of Health and Human Svcs. (Bethesda, Maryland) |
| INVENTOR(S) | Kathryn WESTENDORF (Vancouver, Canada); Stefanie ZENTELIS (Vancouver, Canada); Krithika MUTHURAMAN (Toronto, Canada); Kevin JEPSON (Vancouver, Canada); Ester FALCONER (Vancouver, Canada); John MASCOLA (Bethesda, Maryland); Barney GRAHAM (Bethesda, Maryland); Kizzmekia CORBETT (Bethesda, Maryland); Julie LEDGERWOOD (Bethesda, Maryland); Lingshu WANG (Bethesda, Maryland); Olubukola ABIONA (Bethesda, Maryland); Wei SHI (Bethesda, Maryland); Wing-pui KONG (Bethesda, Maryland); Yi ZHANG (Bethesda, Maryland); Bryan Edward JONES (San Diego, California); Denisa FOSTER (San Diego, California); Julian DAVIES (La Jolla, California); Qing CHAI (San Diego, California); Christopher Carl FRYE (Bargersville, Indiana); Ganapathy GOPALRATHNAM (Fishers, Indiana); Jörg HENDLE (San Diego, California); John Michael SAUDER (Carlsbad, California); Jeffrey Streetman BOYLES (Indianapolis, Indiana); Anna PUSTILNIK (San Diego, California) |
| ABSTRACT | Antibodies that bind SARS-CoV Spike protein, SARS-CoV-2 Spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2. |
| FILED | Thursday, March 04, 2021 |
| APPL NO | 17/192243 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6803 (20170801) A61K 47/6841 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356237 | Li et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MIAMI (Miami, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Wei Li (Miami, Florida); Michelle E. Leblanc (Millbury, Massachusetts); Weiwen Wang (Miami, Florida); Philip J. Rosenfeld (Miami, Florida) |
| ABSTRACT | Antibodies specific for secretogranin III (Scg3) are disclosed. Methods of using the antibodies, antigen-binding fragments thereof, or pharmaceutical compositions comprising the same in the treatment of diseases such as diabetic retinopathy, neovascular age-related macular degeneration, retinopathy of prematurity, and cancer, are also disclosed. |
| FILED | Wednesday, June 29, 2022 |
| APPL NO | 17/853108 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0048 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Peptides C07K 16/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356303 | SMITH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE CURATORS OF THE UNIVERSITY OF MISSOURI (Columbia, Missouri) |
| ASSIGNEE(S) | |
| INVENTOR(S) | JOSIAH SMITH (HARTFORD, Connecticut); BRET ULERY (COLUMBIA, Missouri) |
| ABSTRACT | The present disclosure is directed to novel lipidated poly(amino acid)s (LPAAs). The present disclosure is further related to processes for preparing such novel lipidated poly(amino acid)s (LPAAs) and for preparing novel lipidated poly(amino acid)s nanoparticles (LPAANPs). Additionally, the present disclosure relates to processes for utilizing lipidated poly(amino acid)s (LPAAs) that are biocompatible and capable of drug delivery. |
| FILED | Friday, April 08, 2022 |
| APPL NO | 17/716498 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 9/5123 (20130101) A61K 9/5192 (20130101) A61K 31/704 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 69/04 (20130101) Original (OR) Class C08G 69/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356450 | PORTEUS et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | MATTHEW H PORTEUS (Stanford, California); MICHAEL KYLE CROMER (Stanford, California); DANIEL P. DEVER (Stanford, California); JOAB CAMARENA (Stanford, California) |
| ABSTRACT | The present disclosure provides methods and compositions for genetically modifying hematopoietic stem and progenitor cells (HSPCs), in particular by replacing the HBA1 or HBA2 locus in the HSPCs with a transgene encoding a therapeutic protein. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/740102 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0647 (20130101) Original (OR) Class C12N 15/11 (20130101) C12N 15/861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356461 | Shendure et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Illumina, Inc. (San Diego, California); University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | Illumina, Inc. (San Diego, California); University of Washington (Seattle, Washington) |
| INVENTOR(S) | Jay Shendure (Seattle, Washington); Darren Cusanovich (Seattle, Washington); Riza Daza (Seattle, Washington); Frank Steemers (San Diego, California); Andrew Kennedy (San Diego, California) |
| ABSTRACT | Provided herein are methods for preparing a sequencing library that includes nucleic acids from a plurality of single cells. In one embodiment, the sequencing library includes nucleic acids that represent the chromatin accessibility from the plurality of single cells. In one embodiment, the nucleic acids include three index sequences. In another embodiment, the present disclosure provides methods for characterizing rare events in isolated cells and nuclei. |
| FILED | Friday, December 18, 2020 |
| APPL NO | 17/441741 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1065 (20130101) Original (OR) Class C12N 15/1082 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) C12Q 1/6874 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356467 | LUTHRA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| ASSIGNEE(S) | Board of Regents, The University of Texas System (Austin, Texas) |
| INVENTOR(S) | Rajyalakshmi LUTHRA (Houston, Texas); Dzifa Y. DUOSE (Houston, Texas); Scott KOPETZ (Houston, Texas); Ignacio I. WISTUBA (Houston, Texas); Stephanie ZALLES (Houston, Texas); Saradhi MALLAMPATI (Houston, Texas) |
| ABSTRACT | Provided herein are methods of preparing cell-free DNA (cfDNA) for sequencing such that variant allele frequencies are maintained. Also provided are sequencing libraries prepared according to such methods. In addition, methods are provided for analyzing sequencing reads to determine variant allele frequencies. These methods may be used for diagnosing and/or evaluating cancer patients. |
| FILED | Thursday, June 25, 2020 |
| APPL NO | 17/620605 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1093 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6806 (20130101) Combinatorial Chemistry; Libraries, e.g Chemical Libraries C40B 40/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356469 | Liu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | David R. Liu (Cambridge, Massachusetts); Andrew Vito Anzalone (Cambridge, Massachusetts); James William Nelson (Cambridge, Massachusetts) |
| ABSTRACT | The present disclosure provides compositions and methods for conducting prime editing of a target DNA molecule (e.g., a genome) that enables the incorporation of a nucleotide change and/or targeted mutagenesis. The nucleotide change can include a single-nucleotide change (e.g., any transition or any transversion), an insertion of one or more nucleotides, or a deletion of one or more nucleotides. More in particular, the disclosure provides fusion proteins comprising nucleic acid programmable DNA binding proteins (napDNAbp) and a polymerase (e.g., reverse transcriptase), which is guided to a specific DNA sequence by a modified guide RNA, named an PEgRNA. The PEgRNA has been altered (relative to a standard guide RNA) to comprise an extended portion that provides a DNA synthesis template sequence which encodes a single strand DNA flap, which is homologous to a strand of the targeted endogenous DNA sequence to be edited, but which contains the desired one or more nucleotide changes and which, following synthesis by the polymerase (e.g., reverse transcriptase), becomes incorporated into the target DNA molecule. Also disclosed herein are various methods that leverage prime editing, including treating trinucleotide repeat contraction diseases, installing targeted peptide tags, treating prion disease through the installation of protection mutations, manipulating RNA-encoding genes for the installation of RNA tags for controlling the function and expression of RNA, using prime editing to construct sophisticated gene libraries, using prime editing to insert immunoepitopes into proteins, use of prime editing to insert inducible dimerization domains into protein targets, and delivery methods, among others. |
| FILED | Wednesday, March 31, 2021 |
| APPL NO | 17/219635 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) Original (OR) Class C12N 2310/20 (20170501) C12N 2310/3519 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356512 | CHIU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| ASSIGNEE(S) | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (Seattle, Washington) |
| INVENTOR(S) | Daniel T. CHIU (Seattle, Washington); Jason E. KREUTZ (Seattle, Washington); Gloria S. YEN (Seattle, Washington); Bryant S. FUJIMOTO (Seattle, Washington) |
| ABSTRACT | Methods, devices, and systems for performing digital assays are provided. In certain aspects, the methods, devices, and systems can be used for the amplification and detection of nucleic acids. In certain aspects, the methods, devices, and systems can be used for the recognition, detection, and sizing of droplets in a volume. Also provided are compositions and kits suitable for use with the methods and devices of the present disclosure. |
| FILED | Tuesday, July 19, 2022 |
| APPL NO | 17/813415 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6816 (20130101) Original (OR) Class Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/1434 (20130101) G01N 21/47 (20130101) G01N 21/6428 (20130101) G01N 2015/1445 (20130101) G01N 2021/6439 (20130101) Image Data Processing or Generation, in General G06T 7/62 (20170101) G06T 2207/10056 (20130101) G06T 2207/30072 (20130101) Image or Video Recognition or Understanding G06V 10/507 (20220101) G06V 20/695 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356528 | MALAFA et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (Tampa, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | MOKENGE P. MALAFA (TAMPA, Florida); JENNIFER PERMUTH (TAMPA, Florida); DUNG-TSA CHEN (TAMPA, Florida) |
| ABSTRACT | The current invention pertains to miRNAs that are differentially expressed in samples of an individual having pancreatic cancer, or having a high risk of developing pancreatic cancer, as compared to the corresponding sample of an individual not having pancreatic cancer, or having low risk of developing pancreatic cancer, respectively. In certain embodiments, the miRNAs are differentially expressed in a tissue sample or blood plasma sample of an individual having a pancreatic lesion and having a high risk of developing pancreatic cancer as compared to the corresponding tissue sample or blood sample of an individual having the pancreatic lesion and having no risk or low risk of developing pancreatic cancer. These differentially expressed miRNAs can be used as biomarkers for diagnosis, treatment, and/or prevention of pancreatic cancer, particularly, in a subject having a pancreatic lesion. Microarray containing miRNAs indicative of the presence of pancreatic cancer, or having a high risk of pancreatic cancer development, particularly, in a subject having a pancreatic lesion, and methods of use of the microarrays are also provided. |
| FILED | Friday, December 17, 2021 |
| APPL NO | 17/554476 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356532 | Meltzer et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen J. Meltzer (Lutherville, Maryland); Ke Ma (Hanover, Maryland); Yulan Cheng (Ellicott City, Maryland); John Martin Abraham (Woodbine, Maryland) |
| ABSTRACT | The present invention relates to the field of cancer. More specifically, the present invention provides compositions and methods useful for detecting and treating esophageal cancer. In a specific embodiment, a method for identifying a subject having esophageal adenocarcinoma (EAC) comprises (a) extracting genomic DNA from a sample obtained from the subject; (b) performing a conversion reaction on the genomic DNA in vitro to convert unmethylated cytosine to uracil by deamination; and (c) detecting nucleic acid methylation of one or more genes in the converted genomic DNA, wherein detecting nucleic acid methylation identifies the subject as having EAC. The one or more genes can comprise ABCB1, BMP3, COL23A1, FBN1, FADS1 and PRDM2. In a more specific embodiment, the one or more genes comprise at least three of ABCB1, BMP3, COL23A1, FBN1, FADS1 and PRDM2. |
| FILED | Monday, October 26, 2020 |
| APPL NO | 17/771772 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6858 (20130101) C12Q 1/6886 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356536 | Beebe et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Salus Discovery, LLC (Madison, Wisconsin); Flambeau Diagnostics, LLC (Monona, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Dave Beebe (Monona, Wisconsin); Patrick McMinn (Madison, Wisconsin); Brianna Mullins (Deforest, Wisconsin); Jay Warrick (Madison, Wisconsin) |
| ABSTRACT | Systems, devices, compositions and methods for positioning and/or processing a target are provided. The invention includes systems, devices, methods and related compositions useful, for example, for the separation, isolation, purification, identification, detection and quantification of materials. Also provided are systems and methods for isolation, and/or detection and/or quantification of a target or analyte in a sample. Some systems, devices, compositions and methods comprise oil and aqueous phases stabilized in close proximity to each other. Some systems, devices and methods use a magnetic force to draw a target or carrier-bound through multiple layers. In some embodiments, systems and devices comprise reagents for detection of a target or analyte. |
| FILED | Thursday, May 05, 2022 |
| APPL NO | 17/737788 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502761 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) Original (OR) Class C12Q 1/6806 (20130101) C12Q 1/6851 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356538 | HU et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jianming HU (Hummelstown, Pennsylvania); Ji XI (Hershey, Pennsylvania) |
| ABSTRACT | Provided are compositions and methods for identifying test agents as candidate for use in reducing hepatitis B virus (HBV). The methods involve testing one or more test agents against a mutated HBV core (HBc), wherein the HBc mutation is at HBc amino acid position HBc protein amino acid position 28, 30, 82, 84, 98, 100, 141, 143, 145, 146, 147, 148 or 149 of SEQ ID NO:1 of the HBc. Amounts of HBV cccDNA produced by HBV containing the mutated HBc are determined. The method can be performed in vitro or in vivo. A reduction in cccDNA relative to a control indicates the test agent in the test container is a candidate for reducing HBV in an individual. Cell cultures divided into reaction containers that each contain a distinct test agent are also included. Modified non-human mammals that express or include the mutant HBc proteins are included. |
| FILED | Wednesday, September 23, 2020 |
| APPL NO | 17/763109 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/11 (20130101) C12N 15/63 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/706 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357277 | Shroff et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Servic (Bethesda, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Hari Shroff (Bethesda, Maryland); Abhishek Kumar (Bethesda, Maryland); Shalin B. Mehta (Bethesda, Maryland); Patrick Jean La Riviere (Bethesda, Maryland); Rudolf Oldenbourg (Bethesda, Maryland); Yicong Wu (Bethesda, Maryland); Talon Chandler (Bethesda, Maryland) |
| ABSTRACT | Systems and methods for three-dimensional fluorescence polarization excitation that generates maps of positions and orientation of fluorescent molecules in three or more dimensions are disclosed. |
| FILED | Thursday, July 21, 2022 |
| APPL NO | 17/814096 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6445 (20130101) Original (OR) Class G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 21/02 (20130101) G02B 21/16 (20130101) G02B 21/088 (20130101) G02B 21/367 (20130101) G02B 27/283 (20130101) G02B 27/286 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357278 | Ly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victoria Ly (Santa Cruz, California); Mircea Teodorescu (Santa Cruz, California) |
| ABSTRACT | An alignment platform for use with an imaging device includes an outer stage, an inner stage disposed within the outer stage and flexibly coupled to the outer stage, and a central frame disposed within the inner stage and flexibly coupled to the inner stage. The central frame is configured to support an object being imaged. The inner stage and the central frame are movable relative to the outer stage along a first axis and the central frame is movable relative to outer stage and the inner stage along a second axis that is perpendicular to the first axis. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738262 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Original (OR) Class G01N 21/6486 (20130101) G01N 2201/021 (20130101) G01N 2201/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357309 | BROTMAN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University Of Maryland, Baltimore (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | REBECCA BROTMAN (Baltimore, Maryland); JACQUES RAVEL (Laurel, Maryland); D. ELIZABETH O'HANLON (Baltimore, Maryland) |
| ABSTRACT | This application provides a method for staging bacterial vaginosis (BV), i.e., determining whether a subject does not have BV, has Stage I BV, or has Stage II BV. The method relies on testing for the number and maturity of shed epithelial cells from a sample of vaginal secretion from the subject. Specific diagnosis of Stage I or Stage II BV allows the clinician to provide a targeted and appropriate treatment or treatment course for the subject. |
| FILED | Wednesday, November 04, 2020 |
| APPL NO | 17/774215 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/30 (20130101) G01N 21/8851 (20130101) G01N 33/4833 (20130101) Original (OR) Class G01N 2001/302 (20130101) G01N 2800/36 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357311 | Kaelin et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | William G. Kaelin (Boston, Massachusetts); Vidyasagar Koduri (Brookline, Massachusetts) |
| ABSTRACT | The present application relates, in some aspects, to the development of an assay that uses cell survival and/or cell viability as a phenotypic identifier to positively select for agents that destabilize a protein of interest. |
| FILED | Wednesday, April 20, 2022 |
| APPL NO | 17/725407 |
| CURRENT CPC | Peptides C07K 14/00 (20130101) C07K 14/435 (20130101) C07K 2319/95 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/1211 (20130101) C12N 9/1229 (20130101) C12N 9/1241 (20130101) C12N 9/6472 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/37 (20130101) C12Q 1/485 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/502 (20130101) Original (OR) Class G01N 2500/10 (20130101) G01N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357415 | Wu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Xiaoping Wu (Minneapolis, Minnesota); Xiaodong Ma (Minneapolis, Minnesota); Kamil Ugurbil (Minneapolis, Minnesota) |
| ABSTRACT | Magnetic resonance images with improved image quality consistent with those obtained using parallel radio frequency (“RF”) transmission (“pTx”) techniques are generated from data acquired using single transmission hardware (e.g., single channel RF transmission). A deep-learning framework is used to train a deep neural network to convert images obtained with single transmission into pTx-like images. The pTx-like images have reduced signal variations and dropouts that may otherwise be attributable to B1+ inhomogeneities. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734776 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) Original (OR) Class Computer Systems Based on Specific Computational Models G06N 3/088 (20130101) G06N 3/0454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357566 | Ly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Victoria Ly (Santa Cruz, California); Pierre Baudin (Santa Cruz, California); Yohei Rosen (Santa Cruz, California); Pat Pansodtee (Santa Cruz, California); Kateryna Voitiuk (Santa Cruz, California); David Haussler (Santa Cruz, California); Mircea Teodorescu (Santa Cruz, California) |
| ABSTRACT | An imaging device includes an alignment platform configured to hold a cell culture plate having a plurality of wells and an imaging assembly including a plurality of imaging units, each of which is configured to image one well of the plurality of wells. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738239 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) G02B 21/367 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220358645 | Modayur |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BSOLUTIONS, INC. (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bharath Modayur (Seattle, Washington) |
| ABSTRACT | A system for facilitating developmental monitoring of children comprises one or more processors and one or more hardware storage devices storing instructions that are executable by the one or more processors to configure the system to (i) access a set of image data depicting a subject, (ii) extract a set of features from the set of image data, the set of features indicating one or more body characteristics of the subject as represented in the set of image data, and (iii) determine a set of developmental metrics for the subject based upon the set of features, the set of developmental metrics being indicative of a developmental state for the subject. |
| FILED | Tuesday, May 03, 2022 |
| APPL NO | 17/735650 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/30004 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 15/00 (20180101) G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220359037 | Judson-Torres et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Robert Judson-Torres (San Francisco, California); Maria Wei (San Francisco, California) |
| ABSTRACT | Differentiating benign cutaneous lesions from melanoma is an imprecise and subjective endeavor. The use of micro-RNAs has been investigated, but results have not been consistent across studies and clinical applications are lacking. The invention provides new micro-RNA signatures for differentiating benign lesions from melanoma. The micro-RNA signatures are robust, being stable across detection platforms, diverse sample types, and patient populations. The diagnostic methods based on these signatures control for variations in lesion composition and sample diversity, and permit cross-platform comparisons. The micro-RNA signatures and methods are amenable to the use of samples from convenient non-invasive tape strip biopsy. |
| FILED | Monday, March 25, 2019 |
| APPL NO | 16/980812 |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) C12Q 2600/158 (20130101) C12Q 2600/178 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) Original (OR) Class G16B 40/20 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220359060 | Lee et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Jin Hyung LEE (Stanford, California); Qin LIU (Stanford, California); Onur Cezmi MUTLU (Stanford, California); The Board of Trustees of the Leland Stanford Junior University (Stanford, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jin Hyung Lee (Redwood City, California); Qin Liu (Redwood City, California); Onur Cezmi Mutlu (Redwood City, California) |
| ABSTRACT | Methods, systems, and devices, including computer programs encoded on a computer storage medium are provided for combined dynamic causal modeling and biophysics modeling of brain function. In particular, the disclosed methods of modeling brain function can be used to integrate brain function measurements by two or more methods, such as functional neuroimaging and electrophysiology. Sequential model fitting is used to improve modeling accuracy to generate a more comprehensive model of brain neuronal circuitry. |
| FILED | Wednesday, September 30, 2020 |
| APPL NO | 17/765259 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/377 (20210101) A61B 5/742 (20130101) A61B 5/4076 (20130101) A61B 5/4848 (20130101) A61B 5/7264 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220359071 | Brinkmann et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Benjamin H. Brinkmann (Byron, Minnesota); Tal Pal Attia (Rochester, Minnesota); Squire M. Stead (Bozeman, Montana); Gregory A. Worrell (Rochester, Minnesota); Mona Nasseri (Ponte Vedra Beach, Florida); Boney Joseph (Rochester, Minnesota); Nicholas M. Gregg (Rochester, Minnesota) |
| ABSTRACT | Occurrence of epileptic and other seizures are predicted or otherwise forecasted in ambulatory patients using a wrist-worn device and a trained machine learning algorithm. A multi-stage training process is used to train the machine learning algorithm. A first stage of the training process is implemented on EEG data obtained from bed-ridden, or otherwise non-ambulatory, subjects. A second stage of the training process may be implemented on EEG data obtained from ambulatory subjects. A third stage of the training process is implemented on a variety of data provided by a wrist-worn device. As an example, these data can include one or more of motion data (e.g., accelerometer data), skin temperature data, heart rate data, time of day, and so on. In some implementations, training data can be taken from early portions of each patient's wearable data, while testing results can be computed from the later portions, thereby skipping transfer learning steps. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 17/741272 |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0445 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 40/67 (20180101) Original (OR) Class G16H 50/20 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220360703 | Ly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victoria Ly (Santa Cruz, California); Pierre Baudin (Santa Cruz, California); Pat Pansodtee (Santa Cruz, California); Erik Jung (Santa Cruz, California); Robert Currie (Santa Cruz, California); David Haussler (Santa Cruz, California); Mircea Teodorescu (Santa Cruz, California) |
| ABSTRACT | An imaging system includes an imaging device having a holder configured to hold a cell culture plate with a plurality of wells. The imaging device also includes an imaging assembly having a plurality of imaging units, each of which is configured to image one well of the plurality of wells. The imaging system also includes a storage platform in communication with the imaging device configured to receive a plurality of images from the imaging device. The system further includes a computer in communication with the imaging device and the storage platform. The computer is configured to control the imaging device and to display at least one image of the plurality of images. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738251 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 25/06 (20130101) Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) Image Data Processing or Generation, in General G06T 7/571 (20170101) G06T 2207/10056 (20130101) G06T 2207/10148 (20130101) G06T 2207/30024 (20130101) G06T 2207/30072 (20130101) Pictorial Communication, e.g Television H04N 5/247 (20130101) H04N 5/265 (20130101) H04N 5/23203 (20130101) Original (OR) Class H04N 5/23216 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220360847 | Chukoskie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leanne Chukoskie (San Diego, California); Pamela Cosman (La Jolla, California); Pranav Venuprasad (Framingham, Massachusetts); Anurag Paul (Sunnyvale, California); Tushar Dobhal (Bentonville, Arkansas); Tu Nguyen (Tay Ninh Province, Viet Nam); Andrew Gilman (Tauranga, New Zealand) |
| ABSTRACT | Systems, devices, and methods are disclosed for characterizing joint attention. A method includes dynamically obtaining video streams of participants; dynamically obtaining gaze streams; dynamically providing a cue to the participants to view the object; dynamically detecting a joint gaze based on the gaze streams focusing on the object over a time interval; and dynamically providing feedback based on detecting the joint gaze. |
| FILED | Thursday, June 25, 2020 |
| APPL NO | 17/620082 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/013 (20130101) Pictorial Communication, e.g Television H04N 21/44218 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220360911 | GARUDADRI et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Harinath GARUDADRI (La Jolla, California); Ching-Hua LEE (La Jolla, California); Kuan-Lin CHEN (La Jolla, California); Fred HARRIS (La Jolla, California); Bhaskar RAO (La Jolla, California) |
| ABSTRACT | A method and system or device such as a hearing aid are provided for processing audio signals. In accordance with the method, an audio signal is received and divided into a plurality of frequency sub-bands. For each of the frequency sub-band signals, the signal is further divided into overlapping temporal frames. Each of the temporal frames are windowed. Frequency warping is performed on each of the windowed frames. Overlap-and-add is performed on the frequency warped frames. The frequency warped sub-bands are combined into a full band to provide a frequency warped signal. |
| FILED | Wednesday, September 16, 2020 |
| APPL NO | 17/760842 |
| CURRENT CPC | Loudspeakers, Microphones, Gramophone Pick-ups or Like Acoustic Electromechanical Transducers; Deaf-aid Sets; Public Address Systems H04R 25/453 (20130101) Original (OR) Class H04R 2460/01 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220361323 | Gardner et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Timothy Gardner (Eugene, Oregon); Kara Zappitelli (Oakland, California); Morgan Brown (Eugene, Oregon) |
| ABSTRACT | Methods and systems for fabricating 3D electronic devices, such as multielectrode arrays, including metalized, 3D printed structures using integrated 3D printing and photolithography techniques are disclosed. As one embodiment, a multielectrode array comprises a flexible substrate, a plurality of photopatterned electrical traces spaced apart and insulated from one another on the substrate, and a plurality of 3D printed electrodes. Each 3D printed electrode comprises a photopolymer coated in metal and has a 3D structure that extends outward from the substrate, and each 3D printed electrode is electrically connected to a corresponding electrical trace of the plurality of photopatterned electrical traces. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738817 |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0526 (20130101) Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/124 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) B33Y 40/20 (20200101) B33Y 80/00 (20141201) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 1/09 (20130101) H05K 1/0296 (20130101) Original (OR) Class H05K 1/0346 (20130101) H05K 1/0393 (20130101) H05K 3/06 (20130101) H05K 3/10 (20130101) H05K 2201/0154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 20220354203 | Snow et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Keyport, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jacob Snow (Bremerton, Washington); Jacob Yates (Poulsbo, Washington); Nathan Schuyler (Silverdale, Washington) |
| ABSTRACT | A face shield for use with protective headgear can be shipped flat and easily assembled from a kit of parts without the use of tools or adhesives. The face shield protects against disease, aerosols and splatter that may contain pathogens; may include a curved lower perimeter to facilitate head movements, and can be taken on and off easily. |
| FILED | Tuesday, July 19, 2022 |
| APPL NO | 17/868745 |
| CURRENT CPC | Hats; Head Coverings A42B 3/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354407 | Hsu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| ASSIGNEE(S) | RENSSELAER POLYTECHNIC INSTITUTE (Troy, New York) |
| INVENTOR(S) | Yu-Pin Hsu (Santa Clara, California); Zemin Liu (Santa Clara, California); Mona Mostafa Hella (Watervliet, New York) |
| ABSTRACT | In an embodiment, there is provided an apparatus. The apparatus includes an analog front end for biosignal acquisition. The analog front end includes an instrumentation amplifier and a reconfigurable filter. The instrumentation amplifier is configured to receive a biosignal and includes a super class-AB output stage. The reconfigurable filter is coupled to an output of the instrumentation amplifier. The reconfigurable filter has a selectable gain and an adjustable bandwidth. The bandwidth is adjusted based, at least in part, on a duty cycle of a clock signal. |
| FILED | Wednesday, November 13, 2019 |
| APPL NO | 17/293241 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/301 (20210101) Original (OR) Class A61B 5/304 (20210101) A61B 5/308 (20210101) A61B 5/311 (20210101) A61B 5/7225 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354415 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Quan Zhang (Winchester, Massachusetts); Gary Strangman (Boxford, Massachusetts) |
| ABSTRACT | A system and a method is provided for assessing motion of a biological tissue of a subject including one or more superficial biological layers and a targeted biological layer. An optical perturbation is introduced within the one or more superficial biological layers but not within the targeted biological layer. A set of optical signal data is acquired preceding, during, or following the optical perturbation and, using the set of optical signal data, a set of optical characteristics is determined that is representative of light transiting the biological layers. Using the set of optical characteristics and a model of the biological layers, a target optical signal consistent with a target biological layer is separated and a movement of the desired biological tissue is determined using the target optical signal. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/863002 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/4064 (20130101) Original (OR) Class A61B 5/6814 (20130101) A61B 5/14553 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354669 | Evans et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DEKA Products Limited Partnership (Manchester, New Hampshire) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher O. Evans (Amherst, New Hampshire); N. Christopher Perry (Manchester, New Hampshire); Dirk Albertus van der Merwe (Canterbury, New Hampshire); Christopher C. Langenfeld (Nashua, New Hampshire); John Matthew Kerwin (Manchester, New Hampshire); Stewart M. Coulter (Bedford, New Hampshire); Stanley B. Smith, III (Raymond, New Hampshire); Keith David Violette (Sandown, New Hampshire); Steven W. Nickson (Derry, New Hampshire); Thomas S. Schnellinger (North Andover, Massachusetts); Alexander H. Muller (Manchester, New Hampshire); Gerald Michael Guay (Greenville, New Hampshire) |
| ABSTRACT | A prosthetic arm apparatus including a plurality of segments that provide a user of the prosthetic arm apparatus with substantially the same movement capability and function as a human arm. The segments are connectable to one another and connectable to a prosthetic support apparatus that may be adorned by the user. Each segment of the plurality of segments provides a portion of the movement capability, enabling the plurality of connected segments connected to the harness mount to provide substantially the same movement capability as that lacking in the user. |
| FILED | Wednesday, March 30, 2022 |
| APPL NO | 17/708442 |
| CURRENT CPC | Filters Implantable into Blood Vessels; Prostheses; Devices Providing Patency To, or Preventing Collapsing Of, Tubular Structures of the Body, e.g Stents; Orthopaedic, Nursing or Contraceptive Devices; Fomentation; Treatment or Protection of Eyes or Ears; Bandages, Dressings or Absorbent Pads; First-aid Kits A61F 2/54 (20130101) A61F 2/68 (20130101) A61F 2/581 (20130101) A61F 2/582 (20130101) A61F 2/585 (20130101) Original (OR) Class A61F 2/586 (20130101) A61F 2002/30462 (20130101) A61F 2220/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354818 | Shapiro et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Advanced Neuroresearch Therapeutics LLC (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mark Shapiro (San Antonio, Texas); Fabio A. Vigil (San Antonio, Texas) |
| ABSTRACT | A method for the prevention of brain damage and cognitive dysfunction after blunt or blast types of TBI by a single systemic dose application either intravenous (i.v.) or intraperitoneal (i.p.) of a pharmacological “opener” of KCNQ (“M-type”) potassium ion channels in brain. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734777 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/27 (20130101) Original (OR) Class A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 25/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354930 | Dubé et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HbO2 Therapeutics, LLC (Souderton, Pennsylvania); The Government of the United States, as Represented by the Secretary of the Army (Fort Detrick, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Gregory P. Dubé (Littleton, Massachusetts); Michael A. Meledeo (San Antonio, Texas); Andrew P. Cap (San Antonio, Texas) |
| ABSTRACT | A therapeutic hemoglobin-based oxygen carrier solution is formed by directly combining at least one of freeze-dried platelets and freeze-drug plasma with a hemoglobin-based oxygen carrier. The therapeutic hemoglobin-based oxygen carrier solution can be employed to treat bleeding or anemia and simultaneously increase systemic convective oxygen delivery in a subject suffering low circulatory oxygen transport or bleeding. |
| FILED | Thursday, July 02, 2020 |
| APPL NO | 17/623536 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0026 (20130101) A61K 35/16 (20130101) A61K 35/19 (20130101) A61K 38/42 (20130101) Original (OR) Class A61K 47/02 (20130101) A61K 47/42 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 7/08 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355248 | Sibener et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven J. Sibener (Chicago, Illinois); Michelle R. Brann (Chicago, Illinois); Stephen P. Hansknecht (Chicago, Illinois) |
| ABSTRACT | Provided are apparatus and methods for enriching and separating isotopologues or isotopes. The apparatus and methods enrich and/or separate isotopes or isotopologues present in a substantially monovelocity supersonic beam incident upon a solid surface comprising condensed forms of the isotopologues or the isotopes via the differential condensation of the different isotopologues or isotopes on the surface or the differential reflection of the different isotopologues or isotopes from the surface. |
| FILED | Monday, April 25, 2022 |
| APPL NO | 17/728453 |
| CURRENT CPC | Separation B01D 59/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355263 | Tabor et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States, as represented by the Secretary of the Air Force (Wright-Patterson AFB, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christopher E. Tabor (Kettering, Ohio); Carl J. Thrasher (Beavercreek, Ohio); Alexander M. Watson (Dayton, Ohio); Nicholas J. Morris (Dayton, Ohio); Zachary J. Farrell (Xenia, Ohio) |
| ABSTRACT | The present invention relates to articles comprising core shell liquid metal encapsulate networks and methods of using core shell liquid metal encapsulate networks to control AC signals and power. Such method permits the skilled artisan to control the radiation, transmission, reflection and modulation of an AC signal and power. As a result, AC system properties such as operation frequency, polarization, gain, directionality, insertion loss, return loss, and impedance can be controlled under strain. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/854559 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 13/08 (20130101) Original (OR) Class Cables; Conductors; Insulators; Selection of Materials for Their Conductive, Insulating or Dielectric Properties H01B 1/02 (20130101) H01B 1/08 (20130101) H01B 1/12 (20130101) Antennas, i.e Radio Aerials H01Q 1/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355540 | Meenakshisundaram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ravi Shankar Meenakshisundaram (Aspinwall, Pennsylvania); Mohsen Tabrizi (Pittsburgh, Pennsylvania); Taylor H Ware (Richardson, Texas) |
| ABSTRACT | A four-dimensional (“4D”)-printing or 4D-additive manufacturing method for producing anisotropic macroscopic structures and/or anisotropic macroscopic materials having a plurality of voxels, comprising: providing or forming a first layer of a photocurable first liquid crystalline (LC) monomer; wherein the first layer of the first LC monomer has been provided or formed at a temperature falling within a nematic phase range of the first LC monomer; applying a magnetic field, having a first three-dimensional (“3D”) magnetic field vector with respect to an origin point of a 3D coordinate system, to the first layer of first LC monomer or one or more of the plurality of voxels within the first layer of first LC monomer for a first dwell time, to produce in alignment with the first 3D magnetic field vector a first molecular director and/or first nematic alignment vector within the first layer of first LC monomer or within each of the one or more of the plurality of voxels within the first layer of first LC monomer; exposing the first layer of first LC monomer or the one or more of the plurality of voxels within the first layer of first LC monomer to a first dose of light radiation. |
| FILED | Monday, June 22, 2020 |
| APPL NO | 17/621115 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/129 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355955 | DIGGANS |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Government of the United States as represented by the Secretary of the Air Force (Rome, New York) |
| ASSIGNEE(S) | Government of the United States as represented by the Secretary of the Air Force (Rome, New York) |
| INVENTOR(S) | Christopher Tyler DIGGANS (Fayetteville, New York) |
| ABSTRACT | Various embodiments of the disclosed subject matter provide systems, methods, architectures, mechanisms, apparatus, computer implemented method and/or frameworks configured for tracking Earth orbiting objects and adapting SSN tracking operations to improve tracking accuracy while reducing computational complexity and resource consumption associated with such tracking. |
| FILED | Monday, July 11, 2022 |
| APPL NO | 17/861403 |
| CURRENT CPC | Cosmonautics; Vehicles or Equipment Therefor B64G 3/00 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 19/51 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) Image or Video Recognition or Understanding G06V 10/76 (20220101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356058 | Painter et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Oskar Painter (Sierra Madre, California); Jie Luo (Pasadena, California); Michael T. Fang (Pasadena, California); Alp Sipahigil (Pasadena, California); Paul B. Dieterle (Somerville, Massachusetts); Mahmoud Kalaee (Pasadena, California); Johannes M. Fink (Klosterneuburg, Austria); Andrew J. Keller (Los Angeles, California); Gregory MacCabe (Los Angeles, California); Hengjiang Ren (Pasadena, California); Justin D. Cohen (Annandale, Virginia) |
| ABSTRACT | Embodiments described herein include systems and techniques for converting (i.e., transducing) a quantum-level (e.g., single photon) signal between the three wave forms (i.e., optical, acoustic, and microwave). A suspended crystalline structure is used at the nanometer scale to accomplish the desired behavior of the system as described in detail herein. Transducers that use a common acoustic intermediary transform optical signals to acoustic signals and vice versa as well as microwave signals to acoustic signals and vice versa. Other embodiments described herein include systems and techniques for storing a qubit in phonon memory having an extended coherence time. A suspended crystalline structure with specific geometric design is used at the nanometer scale to accomplish the desired behavior of the system. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/866281 |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 3/0029 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 13/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356225 | ROYBAL et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California); Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kole T. ROYBAL (San Francisco, California); Iowis ZHU (San Francisco, California); Raymond LIU (San Francisco, California); Ahmad S. KHALIL (Boston, Massachusetts); Divya ISRANI (Boston, Massachusetts) |
| ABSTRACT | The present disclosure generally relates to, inter alia, a new class of chimeric Notch receptors containing a synthetic zinc finger transcriptional effector (synZTE) module, engineered to modulate gene expression and cellular activities in a ligand-dependent manner. The new Notch receptors surprisingly retain the ability to transduce signals in response to ligand binding despite that the Notch extracellular subunit, which includes the negative regulatory region previously believed to be essential for the functioning of Notch receptors, is partly or completely deleted. In addition, the synZTE is designed to bind orthogonal DNA target sequences in target organisms which in turn facilitates precise regulation of therapeutic gene expression with minimal off-target activity. Also provided are compositions and methods useful for producing such receptors, nucleic acids encoding same, host cells genetically modified with the nucleic acids, as well as methods for modulating an activity of a cell and/or for treatment of various health conditions. |
| FILED | Wednesday, September 23, 2020 |
| APPL NO | 17/763122 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) Original (OR) Class C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70578 (20130101) C07K 16/2803 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356229 | WESTENDORF et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AbCellera Biologics Inc. (Vancouver, Canada); The United States of America, as represented by the Secretary, Department of Health and Human Svcs. (Bethesda, Maryland) |
| ASSIGNEE(S) | AbCellera Biologics Inc. (Vancouver, Canada); The United States of America, as represented by the Secretary, Department of Health and Human Svcs. (Bethesda, Maryland) |
| INVENTOR(S) | Kathryn WESTENDORF (Vancouver, Canada); Stefanie ZENTELIS (Vancouver, Canada); Krithika MUTHURAMAN (Toronto, Canada); Kevin JEPSON (Vancouver, Canada); Ester FALCONER (Vancouver, Canada); John MASCOLA (Bethesda, Maryland); Barney GRAHAM (Bethesda, Maryland); Kizzmekia CORBETT (Bethesda, Maryland); Julie LEDGERWOOD (Bethesda, Maryland); Lingshu WANG (Bethesda, Maryland); Olubukola ABIONA (Bethesda, Maryland); Wei SHI (Bethesda, Maryland); Wing-pui KONG (Bethesda, Maryland); Yi ZHANG (Bethesda, Maryland); Bryan Edward JONES (San Diego, California); Denisa FOSTER (San Diego, California); Julian DAVIES (La Jolla, California); Qing CHAI (San Diego, California); Christopher Carl FRYE (Bargersville, Indiana); Ganapathy GOPALRATHNAM (Fishers, Indiana); Jörg HENDLE (San Diego, California); John Michael SAUDER (Carlsbad, California); Jeffrey Streetman BOYLES (Indianapolis, Indiana); Anna PUSTILNIK (San Diego, California) |
| ABSTRACT | Antibodies that bind SARS-CoV Spike protein, SARS-CoV-2 Spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2. |
| FILED | Thursday, March 04, 2021 |
| APPL NO | 17/192243 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6803 (20170801) A61K 47/6841 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356348 | Epshteyn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Albert Epshteyn (College Park, Maryland); Matthew Laskoski (Springfield, Virginia); Brian Chaloux (Alexandria, Virginia); Tristan Butler (Alexandria, Virginia) |
| ABSTRACT | Carbon phosphonitride (CPN) including tricyanophosphine (P(CN)3), its pre-polymer (CPN-PP), and/or solid CPN (C3N3P) can serve as a useful additive for thermoset resins, resulting in improved thermal and mechanical properties. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734921 |
| CURRENT CPC | Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 5/50 (20130101) Compositions of Macromolecular Compounds C08L 63/00 (20130101) C08L 71/123 (20130101) Original (OR) Class C08L 79/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356583 | Brown et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert F. Brown (Summerland Key, Florida); Gregory M. Smith (Alexandria, Virginia) |
| ABSTRACT | Methods are provided for a post-treatment process for use with coatings deposited via thermal spray and/or cold spray to modify the microstructures of the coatings and improve associated cohesion and adhesion properties. Such process includes performing ultrasonic consolidation of the spray coating as a post-treatment step after deposition of the spray coating onto a substrate. A system for spray deposition and ultrasonic consolidation is also provided. |
| FILED | Wednesday, April 28, 2021 |
| APPL NO | 17/242445 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 3/002 (20130101) B05D 3/007 (20130101) B05D 3/12 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 4/02 (20130101) C23C 4/06 (20130101) C23C 4/123 (20160101) C23C 24/04 (20130101) Original (OR) Class C23C 28/021 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356807 | Karafillis et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Apostolos Pavlos Karafillis (Winchester, Massachusetts); Eric Dean Jorgensen (Upton, Massachusetts); Craig Douglas Young (Blanchester, Ohio); Jonathan Harry Kerner (Brookline, Massachusetts); Leonardo Ajdelsztajn (Niskayuna, New York) |
| ABSTRACT | A component for a turbine engine may be formed by spraying particulate with a nozzle toward a substrate. The particulate may be deposited to form one or more annular layers and a reinforcing structure. The component may be a closed loop annular component having a reinforcing structure of specific dimensions enabled by the methods described. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/307394 |
| CURRENT CPC | Processes for Applying Fluent Materials to Surfaces, in General B05D 1/12 (20130101) Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 9/06 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2230/31 (20130101) F05D 2260/606 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356834 | Cecil |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Cummins Inc. (Columbus, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Adam C. Cecil (Columbus, Indiana) |
| ABSTRACT | Pistons and piston assemblies for an internal combustion engine is provided. The piston assembly includes a piston coupled to a connecting rod with a piston pin. The piston pin includes a non-circular outer cross-sectional shape. |
| FILED | Tuesday, May 03, 2022 |
| APPL NO | 17/661778 |
| CURRENT CPC | Cooling of Machines or Engines in General; Cooling of Internal-combustion Engines F01P 3/08 (20130101) Original (OR) Class Cylinders, Pistons or Casings, for Combustion Engines; Arrangements of Sealings in Combustion Engines F02F 3/18 (20130101) Pistons; Cylinders; Sealings F16J 1/005 (20130101) F16J 1/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356841 | Bacon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| ASSIGNEE(S) | Textron Innovations Inc. (Providence, Rhode Island) |
| INVENTOR(S) | Bruce Bennett Bacon (Euless, Texas); Kristine Joyce Lazo (Dallas, Texas); Shawn Patrick Leonard, JR. (Fort Worth, Texas) |
| ABSTRACT | An air intake system for an aircraft, which is switchable between a performance mode and a filtered mode, includes a duct forming filtered air inlet slits. The air intake system also includes interconnected gills adjacent to the filtered air inlet slits. The gills are movable between various gill positions including a closed position substantially covering the filtered air inlet slits and an open position substantially exposing the filtered air inlet slits. The air intake system also includes an actuator configured to move the gills into the closed position in the performance mode and the open position in the filtered mode. |
| FILED | Thursday, May 06, 2021 |
| APPL NO | 17/313267 |
| CURRENT CPC | Equipment for Fitting in or to Aircraft; Flying Suits; Parachutes; Arrangements or Mounting of Power Plants or Propulsion Transmissions in Aircraft B64D 33/02 (20130101) B64D 2033/0253 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/057 (20130101) Original (OR) Class Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/329 (20130101) F05D 2240/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356966 | Gamache et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raymond Mark Gamache (Salinas, California); Christopher Marc LeTorre Phifer (Grosse Pointe, Michigan) |
| ABSTRACT | A self-sealing hose includes an inner rubber layer comprising a first rubber material; and an outer rubber layer comprising a second rubber material. The second rubber material has an ultimate strain of at least 100% and an elastic limit of at least about 7 MPa. The first rubber material has a modulus measured at 250% elongation of less than about 10 kPa. |
| FILED | Wednesday, May 04, 2022 |
| APPL NO | 17/736914 |
| CURRENT CPC | Pipes; Joints or Fittings for Pipes; Supports for Pipes, Cables or Protective Tubing; Means for Thermal Insulation in General F16L 11/12 (20130101) Original (OR) Class F16L 11/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357137 | Gupta et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Washington State University (Pullman, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yogendra M. Gupta (Spokane, Washington); Atakan Peker (Spokane, Washington) |
| ABSTRACT | Munitions structures comprising one or more high strength reactive alloys, in particular reactive bulk metallic glasses, have significant amounts of inherent chemical energy. This energy may be discharged by subjection of the munitions structure to rapid impulsive loading and fragmentation in the presence of oxygen and/or nitrogen. A munitions structure can be configured in both large and small penetrators, e.g. warheads and bullets, with increased lethality. The lethality of these munitions structures is augmented by means of rapidly and simultaneously imparting both mechanical energy (kinetic energy through impact and fragmentation) and chemical energy (blast and/or fireball) to a target. A high-strength reactive alloy can substitute at least in part one or both of explosives and inert structural materials in conventional munitions systems to improve performance and reduce parasitic weight of structural casing. |
| FILED | Friday, March 04, 2022 |
| APPL NO | 17/687387 |
| CURRENT CPC | Alloys C22C 1/02 (20130101) Explosive Charges, e.g for Blasting, Fireworks, Ammunition F42B 12/74 (20130101) F42B 12/207 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357191 | Jones |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Johns Hopkins University (Baltimore, Maryland) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jonathan P. Jones (Hanover, Maryland) |
| ABSTRACT | A mass flow meter includes an arcuate tube section that is semi-circular, an inner pressure sensor disposed on an inner curvature portion of the arcuate tube section and configured to capture an inner pressure measurement of the flowing fluid, an outer pressure sensor disposed on an outer curvature portion of the arcuate tube section and configured to capture an outer pressure measurement of the flowing fluid, and processing circuitry. The processing circuitry may be configured to receive the inner pressure measurement and the outer pressure measurement, determine a pressure difference between the inner pressure measurement and the outer pressure measurement, and determine a mass flow rate of the flowing fluid passing through the arcuate tube section based on the pressure difference and a fluid density of the flowing fluid. |
| FILED | Thursday, March 10, 2022 |
| APPL NO | 17/691231 |
| CURRENT CPC | Measuring Volume, Volume Flow, Mass Flow or Liquid Level; Metering by Volume G01F 1/80 (20130101) Original (OR) Class G01F 1/684 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357279 | Masson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Laura E. Masson (Nashville, Tennessee); Anita Mahadevan-Jansen (Nashville, Tennessee) |
| ABSTRACT | A system for real-time assessment of systemic hydration includes a light source configured to operably emit light of first and second wavelengths; means for delivering the emitted light to a target site to excite at least one first spot at the target site, and collecting Raman scattering light scattered from the target site at a plurality of second spots; a detector coupled with said means for obtaining a plurality of spatially offset Raman spectra from the collected Raman scattering light, each spatially offset Raman spectrum corresponding to a respective second spot of the target site and associated with a depth of tissues at which the Raman scattering light is scattered; and a controller configured to process the plurality of spatially offset Raman spectra so as to identify spectral features from the plurality of spatially offset Raman spectra, and assess systemic hydration from the identified spectral features. |
| FILED | Thursday, March 10, 2022 |
| APPL NO | 17/691567 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/256 (20210101) A61B 5/1455 (20130101) Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/10 (20130101) G01J 3/021 (20130101) G01J 3/0218 (20130101) G01J 3/2803 (20130101) G01J 3/4412 (20130101) G01J 2003/2859 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220357631 — AN OPTICAL SWITCH DEVICE CONFIGURED FOR TOPOLOGICAL LIGHT STEERING AND RELATED METHODS
| US 20220357631 | Feng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Liang Feng (Wynnewood, Pennsylvania); Han Zhao (Philadelphia, Pennsylvania) |
| ABSTRACT | An optical switch device and a related method for defining a topological light transport channel in a photonic lattice are provided. An exemplary optical switch device includes a photonic lattice including a photonic topological microring array comprising a plurality of site rings coupled via a plurality of anti-resonant link rings, a plurality of input light ports and a plurality of output light ports located at the plurality of site rings, wherein the plurality of input light ports and the plurality of output light ports are respectively connected by a plurality of topological light transport channels. The optical switch device is further configured such that each of the topological light transport channels is defined by a gain domain area that is produced by a corresponding patterned optical pumping beam emitted onto the photonic topological microring array. |
| FILED | Monday, September 14, 2020 |
| APPL NO | 17/642396 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/313 (20130101) Original (OR) Class G02F 2202/102 (20130101) G02F 2203/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357933 | Alhanahnah et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Mohannad Alhanahnah (Madison, Wisconsin); Vaibhav Rastogi (Santa Clara, California); Somesh Jha (Madison, Wisconsin); Thomas Reps (Madison, Wisconsin) |
| ABSTRACT | A computerized technique for program simplification and specialization combines a partial interpretation of the program based on a subset of program functions to obtain variable states with concrete values at a program “neck.” These concrete values are then propagated as part of an optimization transformation that simplifies the program based on these constant values, for example, by eliminating branches that are never taken based on the constant values. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738158 |
| CURRENT CPC | Electric Digital Data Processing G06F 8/443 (20130101) G06F 8/452 (20130101) G06F 8/4443 (20130101) Original (OR) Class G06F 9/445 (20130101) G06F 9/45504 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220358374 | SUD |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Aerospace Corporation (El Segundo, California) |
| ASSIGNEE(S) | The Aerospace Corporation (El Segundo, California) |
| INVENTOR(S) | Seema SUD (Reston, Virginia) |
| ABSTRACT | A waveform analysis and vulnerability assessment (WAVE) tool is disclosed that can analyze the characteristics and vulnerabilities of waveforms. The WAVE tool may identify issues in waveforms prior to their implementation in a transmit device or building the back-end processing to receive the waveform at a ground station. The WAVE tool may quantify waveform vulnerabilities, address which vulnerabilities a particular waveform has, and enable the user to modify the waveform design to optimize its performance against threats prior to implementation. Additionally, the WAVE tool may save time and money since new waveforms can be vetted against the tool before implementation. Data from waveforms can be analyzed against a plurality of metrics and scores can be generated providing a quantitative assessment of waveform performance. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244197 |
| CURRENT CPC | Electric Digital Data Processing G06F 17/142 (20130101) Computer Systems Based on Specific Computational Models G06N 5/04 (20130101) Original (OR) Class G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220358630 | Goldfine et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | JENTEK Sensors, Inc. (Marlborough, Massachusetts) |
| ASSIGNEE(S) | JENTEK Sensors, Inc. (Marlborough, Massachusetts) |
| INVENTOR(S) | Neil J. Goldfine (Cocoa Beach, Florida); Andrew P. Washabaugh (Chula Vista, California); Mark Windoloski (Chelmsford, Massachusetts) |
| ABSTRACT | A system and method are disclosed for enhancing pit detection and sizing in a test object. Response signatures are created and stored in a signature library to characterize various sensor responses (liftoff, orientation) and pit properties (e.g., depth, width), possibly with or without additional considerations (e.g., edges, cracks). A sensor is placed on and scanned across a surface of interest on the test object. During scanning the sensor is measured repeatedly at regular intervals. An encoder may be used to record the sensor position for each measurement. The measurement results are then correlated with one or more signatures in the signature library. A threshold is used to determine if the correlation is indicative of the detection of a pit. If so additional processing may be performed to estimate pit properties. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/662634 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/9515 (20130101) Image Data Processing or Generation, in General G06T 7/001 (20130101) Original (OR) Class G06T 2207/30136 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220359226 | Harrison et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Joel T. Harrison (Henrico, Virginia); Mool C. Gupta (Keswick, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia); University of Virginia (Charlottesville, Virginia) |
| INVENTOR(S) | Joel T. Harrison (Henrico, Virginia); Mool C. Gupta (Keswick, Virginia) |
| ABSTRACT | A laser sintering deposition method for disposing lead selenide onto a substrate. The method includes: wet-milling a lead selenide ingot mixed with methanol into a colloidal slurry containing nanocrystals; separating the colloidal slurry into nanocrystal particles and the methanol; depositing the nanocrystal particles to a substrate; and emitting coherent infrared light onto the nanocrystal particles for fusing into a lead selenide crystalline film. Afterwards, the lead selenide film can be exposed to oxygen to form a lead selenite layer, and subsequently to iodine gas to produce a lead iodide layer onto the lead selenite layer. |
| FILED | Friday, April 29, 2022 |
| APPL NO | 17/732775 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/477 (20130101) Original (OR) Class H01L 21/02354 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220359990 | BORYSSENKO |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | SI2 Technologies, Inc. (North Billerica, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Anatoliy BORYSSENKO (Belchertown, Massachusetts) |
| ABSTRACT | Antenna elements are described that may include a radiator, a feeding portion, a first impedance transformer, a balun, and a second impedance transformer. The first impedance transformer, balun, and second impedance transformer may be disposed above a ground plane of an antenna array to reduce a bulk of the array. The array can also include a dielectric top layer for loading apertures of the antenna array. The antenna elements can also include anomaly suppressors can be provided to cancel common-mode resonances from the radiators. |
| FILED | Monday, March 21, 2022 |
| APPL NO | 17/699843 |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 9/16 (20130101) Original (OR) Class H01Q 9/065 (20130101) H01Q 21/0006 (20130101) H01Q 21/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220360281 | DJORDJEVIC et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ivan B. DJORDJEVIC (Tucson, Arizona); Xiaole SUN (Tucson, Arizona) |
| ABSTRACT | Disclosed are systems, methods, and software for generating spatially-coupled low-density parity-check (SC-LDPC) codes. A method for generating SC-LDPC codes includes generating one or more quasi-cyclic low-density parity-check (QC-LDPC) codes, and also includes assigning at least one of the generated one or more QC-LDPC codes as one or more template codes. The method further includes copying at least a portion of the one or more template codes to introduce irregularity. The method also includes shifting one or more template codes on a sub-block basis to generate at least one SC-LDPC code. As compared to known LDPC code generation modalities, the disclosed invention provides a simplified technique for implementation in streamlined hardware which has more general applicability across both present, and anticipated, communication systems, including those adapted for use with optical communications, wireless communications, and 5G as well as future 6G. |
| FILED | Friday, June 26, 2020 |
| APPL NO | 17/621639 |
| CURRENT CPC | Coding; Decoding; Code Conversion in General H03M 13/116 (20130101) Original (OR) Class H03M 13/616 (20130101) H03M 13/1154 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220360540 | Brewer |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Tony Brewer (Plano, Texas) |
| ABSTRACT | A transmitting device generates multiple small packets for a large packet and transmits them to a receiving device. Routing devices forward the multiple small packets to the receiving device. Each of the smaller packets, except the last packet, has a sequence indicator set. As a result, the receiving device is able to determine that each of the smaller packets is part of a larger packet and buffer the smaller packets or their payloads. When the last packet is received, the larger packet is complete and may be processed by the receiving device. The routing devices delay requests from other transmitting devices to transmit data to the receiving device until the last packet is sent to the receiving device. The routing devices may continue to route traffic to the receiving device on all virtual channels other than a virtual channel being used for the large packet. |
| FILED | Thursday, July 14, 2022 |
| APPL NO | 17/865111 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 45/74 (20130101) H04L 47/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220360649 | Patrick et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | |
| INVENTOR(S) | David Patrick (McKinney, Texas); Tony Brewer (Plano, Texas) |
| ABSTRACT | Implementations of the present disclosure are directed to systems and methods for processing headers that support multiple protocols. A header of a packet includes a bridge type (BTYPE) field that indicates the protocol of the packet. A command field of the packet is interpreted differently based on the value of the BTYPE field. Among the benefits of implementations of the present disclosure is that a single network may be used to carry packets of different protocols without the overhead of encapsulation. |
| FILED | Thursday, July 14, 2022 |
| APPL NO | 17/865141 |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 47/2441 (20130101) H04L 69/16 (20130101) H04L 69/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220361298 | Hoff et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Government of the United States of America, as represented by the Secretary of the Air Force (Kirtland AFB, New Mexico) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Brad Winston Hoff (Albuquerque, New Mexico); David Michael French (Portland, Oregon) |
| ABSTRACT | An electrode is embedded in a piece of ceramic material having a population of conduction band electrons. Applying a voltage bias to the electrode causes electrons to flow towards or away from the electrode to form a positively charged sheath either a distance apart from or adjacent the electrode, depending the polarity of the bias. The electron flow also forms a negatively charged sheath lying opposite the positively charged sheath, and an electrically neutral region lying between the two sheaths. Electromagnetic radiation impinging the ceramic material heats the ceramic where the radiation is absorbed by the electron population. As the incident radiation is absorbed in proportion to the electron density, heating is increased in the negatively charged sheath, relative to the other parts of the ceramic material. The location of heating is controlled by controlling the magnitude and polarity of the voltage bias. |
| FILED | Wednesday, June 29, 2022 |
| APPL NO | 17/853343 |
| CURRENT CPC | Electric Heating; Electric Lighting Not Otherwise Provided for H05B 6/00 (20130101) H05B 6/02 (20130101) Original (OR) Class H05B 6/46 (20130101) H05B 6/64 (20130101) H05B 6/68 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 20220354974 | Wilbur et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Washington (Seattle, Washington) |
| ASSIGNEE(S) | University of Washington (Seattle, Washington) |
| INVENTOR(S) | D. Scott Wilbur (Seattle, Washington); Ming-Kuan Chyan (Seattle, Washington); Donald K. Hamlin (Seattle, Washington) |
| ABSTRACT | Reagents and methods for labeling biomolecules with astatine isotopes in higher oxidation states. The reagents and methods allow for efficient labeling of biomolecules, such as antibodies, without the formation of high molecular weight by products that arise due to 211At-promoted dimerization and higher aggregation of the conjugated biomolecules, and diminish cellular retention of astatine caused by cellular oxidization of the bonded astatine atom in vivo. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 17/730130 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/10 (20130101) Original (OR) Class General Methods of Organic Chemistry; Apparatus Therefor C07B 2200/05 (20130101) Acyclic, Carbocyclic or Heterocyclic Compounds Containing Elements Other Than Carbon, Hydrogen, Halogen, Oxygen, Nitrogen, Sulfur, Selenium or Tellurium C07F 5/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355260 | MAGRINI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kimberly A. MAGRINI (Golden, Colorado); Michael William SPRAGUE (Golden, Colorado); Zia ABDULLAH (Littleton, Colorado); Jessica L. OLSTAD-THOMPSON (Arvada, Colorado); Reinhard SEISER (Golden, Colorado) |
| ABSTRACT | The present disclosure relates to a device for directing a coking-prone liquid to a high temperature environment, where the device includes an inner tube positioned concentrically within an outer tube, creating a first annular space between an outer wall of the inner tube and an inner wall of the outer tube and a first intermediate tube positioned concentrically around the outer tube, creating a second annular space. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 17/740458 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 4/002 (20130101) Original (OR) Class B01J 8/20 (20130101) B01J 8/1854 (20130101) B01J 8/1872 (20130101) B01J 2204/002 (20130101) B01J 2208/00902 (20130101) Cracking Hydrocarbon Oils; Production of Liquid Hydrocarbon Mixtures, e.g by Destructive Hydrogenation, Oligomerisation, Polymerisation; Recovery of Hydrocarbon Oils From Oil-shale, Oil-sand, or Gases; Refining Mixtures Mainly Consisting of Hydrocarbons; Reforming of Naphtha; Mineral Waxes C10G 11/18 (20130101) C10G 2300/1074 (20130101) C10G 2300/4056 (20130101) C10G 2300/4075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355342 | Kumar et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sortera Alloys, Inc. (Fort Worth, Texas) |
| ASSIGNEE(S) | Sortera Alloys, Inc. (Fort Worth, Texas) |
| INVENTOR(S) | Nalin Kumar (Fort Worth, Texas); Manuel Gerardo Garcia, JR. (Fort Wayne, Indiana) |
| ABSTRACT | A material sorting system sorts materials utilizing a vision system that implements a machine learning system in order to identify or classify each of the materials, which are then sorted into separate groups based on such an identification or classification. The material sorting system can sort material pieces containing contaminants, such as copper from steel. |
| FILED | Tuesday, May 24, 2022 |
| APPL NO | 17/752669 |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 5/04 (20130101) B07C 5/34 (20130101) B07C 5/342 (20130101) B07C 5/3422 (20130101) Original (OR) Class B07C 2501/0054 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355414 | Sartin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Honeywell Federal Manufacturing and Technologies, LLC (KANSAS CITY, Missouri) |
| ASSIGNEE(S) | Honeywell Federal Manufacturing and Technologies, LLC (KANSAS CITY, Missouri) |
| INVENTOR(S) | Bryan Sartin (KANSAS CITY, Missouri); Michael McNary (KANSAS CITY, Missouri) |
| ABSTRACT | A laser welding system for welding a component and reducing defects in the weld by ensuring uniform, laminar gas flow over a process area of the system. The laser welding system comprises a laser for welding the component, a platform for supporting the component, an enclosure surrounding the platform, a first actuatable barrier, a second actuatable barrier, an actuator, and a controller. The enclosure includes a plurality of walls, one of the walls having an inlet and another wall having an outlet. The inlet and outlet each having an opening having a cross-sectional area for letting gas flow through. The first and second barriers are configured to modify the cross-sectional areas of the openings when actuated. The actuator is configured to actuate the barriers, and the controller is configured to direct the actuator to actuate the barriers so that the cross-sectional area of the first opening is larger than the cross-sectional area of the second opening so that a pressure at the inlet is greater than a pressure at the outlet. |
| FILED | Thursday, May 26, 2022 |
| APPL NO | 17/825026 |
| CURRENT CPC | Soldering or Unsoldering; Welding; Cladding or Plating by Soldering or Welding; Cutting by Applying Heat Locally, e.g Flame Cutting; Working by Laser Beam B23K 26/127 (20130101) B23K 26/142 (20151001) Original (OR) Class B23K 26/144 (20151001) B23K 26/1436 (20151001) B23K 26/1464 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355558 | KAMPASI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Komal KAMPASI (San Francisco, California); Razi-Ul Muhammad HAQUE (San Francisco, California); Michael Gregory TRIPLETT (Pleasanton, California) |
| ABSTRACT | The present disclosure relates to methods of forming a fiber optic core, and a fiber optic component with a highly uniform cladding covering the fiber optic core. In one microfabrication process a first sacrificial tubing is provided which has a predetermined inner diameter. A quantity of a curable polymer is also provided. The first sacrificial tubing is at least partially filled with the curable polymer. The curable polymer is then cured. The first sacrificial tubing is then removed to produce a finished fiber optic core. Additional operations may be performed by which the fiber optic core is placed inside a thermoplastic tubing, which is itself placed inside a sacrificial heat shrink. Heat is applied to reflow the thermoplastic tubing around the fiber optic core, thus forming a highly uniform thickness cladding. When the sacrificial heat shrink tubing is removed a finished fiber optic component is present. Additional microfabrication methods are disclosed which involve dip coating a pre-formed fiber optic core in a polymer, and then curing the polymer to form a finished fiber optic component with a uniform thickness cladding. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/307833 |
| CURRENT CPC | Producing Particular Articles From Plastics or From Substances in a Plastic State B29D 11/00663 (20130101) Original (OR) Class B29D 11/00875 (20130101) Optical Elements, Systems, or Apparatus G02B 6/02033 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355905 | Lynn et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Other Lab, LLC (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Peter Sturt Lynn (Alameda, California); Jonathan B. Pompa (Long Beach, California) |
| ABSTRACT | An upweller array configured to be disposed in a body of water and that has one or more upweller systems. The one or more upweller systems include a buoy configured to float on the surface of the body of water, a tether coupled to the buoy and a hydrofoil rotor coupled to the tether. The hydrofoil rotor is configured to be disposed in the body of water based on a length of the tether. |
| FILED | Tuesday, May 10, 2022 |
| APPL NO | 17/741250 |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 33/00 (20130101) Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 61/65 (20170101) Ships or Other Waterborne Vessels; Equipment for Shipping B63B 1/246 (20130101) B63B 22/04 (20130101) Original (OR) Class B63B 79/10 (20200101) Marine Propulsion or Steering B63H 11/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356495 | GUARNIERI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Alliance for Sustainable Energy, LLC (Golden, Colorado) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael T. GUARNIERI (Denver, Colorado); Rabea JESSER (Staunton, Virginia) |
| ABSTRACT | Disclosed herein are methods and compositions of matter that enable the biological conversion of gaseous waste streams (CO2, stranded natural gas, flue gas, biogas, landfill gas, etc.) to a platform chemical, 3-hydroxybutyrate, which can in turn be upgraded to fuels and polymers (e.g. polypropylene and polymers). The technology thus presents both a mechanism to valorize gaseous waste streams and establish sustainable production routes to chemicals and plastics via the overexpression of PHB depolymerase while knocking out the AACS pathway in this specific strain of methanotrophic bacteria. |
| FILED | Monday, April 04, 2022 |
| APPL NO | 17/657902 |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/205 (20210501) C12N 15/52 (20130101) C12N 15/74 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) Original (OR) Class Indexing Scheme Associated With Subclasses C12C - C12Q, Relating to Microorganisms C12R 2001/01 (20210501) Enzymes C12Y 203/01019 (20130101) C12Y 207/02007 (20130101) C12Y 301/01075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356545 | Popovs et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ilja Popovs (Knoxville, Tennessee); Henry Musrock (East Lansing, Michigan); Katherine R. Johnson (Knoxville, Tennessee); Bruce A. Moyer (Oak Ridge, Tennessee) |
| ABSTRACT | Lithium extractant compounds having the following structure: wherein: Ra and Rb are independently selected from the group consisting of hydrocarbon groups (R), —OR, —NRR′, —SR, —SO2R, —SO2NR2, —C(O)R, —C(O)OR, —C(O)NRR′, —C(S)OR, —C(O)SR, and —C(S)NRR′; R′ is selected from R′ groups, wherein R′ is selected from H and R groups; X is O or OH; Y is C or N, wherein, when Y is N, then Ra is R. Also described are hydrophobic water-insoluble solutions containing at least one extractant compound of Formula (1). Also described is a method for extracting lithium from an aqueous solution by contacting the aqueous solution with the hydrophobic solution, and optional stripping of lithium from the hydrophobic solution by contacting the hydrophobic solution with an aqueous stripping solution. |
| FILED | Friday, April 22, 2022 |
| APPL NO | 17/726890 |
| CURRENT CPC | Compounds of Alkali Metals, i.e Lithium, Sodium, Potassium, Rubidium, Caesium, or Francium C01D 15/00 (20130101) Acyclic or Carbocyclic Compounds C07C 235/74 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 3/34 (20210501) C22B 3/36 (20210501) C22B 26/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356602 | HAN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Yale University (New Haven, Connecticut) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Jung HAN (New Haven, Connecticut); Bingjun LI (New Haven, Connecticut) |
| ABSTRACT | Methods and systems for in-situ and selective area etching of surfaces or layers, and high-speed growth of gallium nitride (GaN), by organometallic chlorine (Cl) precursors, are described herein. In one aspect, a method can include exposing a GaN layer or surface to an organometallic Cl precursor within a reactor under conditions sufficient to etch the layer or surface, thereby etching the GaN layer or surface. In another aspect, a method of growing GaN can include inputting a set of reactants comprising at least trimethylgallium (TMGa) and anunonia into an OMVPE reactor; inputting an organometallic Cl precursor into the OMVPE reactor; and reacting the Cl precursor with the TM Ga and with the NH3 to deposit GaN by organometallic vapor phase epitaxy. |
| FILED | Tuesday, June 16, 2020 |
| APPL NO | 17/620182 |
| CURRENT CPC | Single-crystal-growth; Unidirectional Solidification of Eutectic Material or Unidirectional Demixing of Eutectoid Material; Refining by Zone-melting of Material; Production of a Homogeneous Polycrystalline Material With Defined Structure; Single Crystals or Homogeneous Polycrystalline Material With Defined Structure; After-treatment of Single Crystals or a Homogeneous Polycrystalline Material With Defined Structure; Apparatus Therefor C30B 25/16 (20130101) C30B 25/186 (20130101) C30B 29/406 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356761 | ZHANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Xiaosheng ZHANG (Berkeley, California); Ming Chiang A WU (Moraga, California); Andrew S MICHAELS (Berkeley, California); Johannes HENRIKSSON (Berkeley, California) |
| ABSTRACT | An integrated-optics MEMS-actuated beam-steering system is disclosed, wherein the beam-steering system includes a lens and a programmable vertical coupler array having a switching network and an array of vertical couplers, where the switching network can energize of the vertical couplers such that it efficiently emits the light into free-space. The lens collimates the light received from the energized vertical coupler and directs the output beam along a propagation direction determined by the position of the energized vertical coupler within the vertical-coupler array. In some embodiments, the vertical coupler is configured to correct an aberration of the lens. In some embodiments, more than one vertical coupler can be energized to enable steering of multiple output beams. In some embodiments, the switching network is non-blocking. |
| FILED | Thursday, July 14, 2022 |
| APPL NO | 17/865131 |
| CURRENT CPC | Fixed or Movable Closures for Openings in Buildings, Vehicles, Fences or Like Enclosures in General, e.g Doors, Windows, Blinds, Gates E06B 9/34 (20130101) E06B 9/42 (20130101) E06B 9/80 (20130101) Original (OR) Class E06B 9/325 (20130101) E06B 9/326 (20130101) Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/292 (20130101) G02F 1/3132 (20130101) G02F 1/3137 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357116 | YANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regent of the University of Colorado, A Body Corporate (Denver, Colorado); University of Wyoming (Laramie, Wyoming) |
| ASSIGNEE(S) | The Regents of the University of Colorado, A Body Corporate (Denver, Colorado); University of Wyoming (Laramie, Wyoming) |
| INVENTOR(S) | Ronggui YANG (Boulder, Colorado); Xiaobo YIN (Boulder, Colorado); Gang TAN (Fort Collins, Colorado); Dongliang ZHAO (Boulder, Colorado); Yaoguang MA (Boulder, Colorado); Yao ZHAI (Boulder, Colorado) |
| ABSTRACT | Polymer-based selective radiative cooling structures are provided which include a selectively emissive layer of a polymer or a polymer matrix composite material. Exemplary selective radiative cooling structures are in the form of a sheet, film or coating. Also provided are methods for removing heat from a body by selective thermal radiation using polymer-based selective radiative cooling structures. |
| FILED | Friday, June 24, 2022 |
| APPL NO | 17/849481 |
| CURRENT CPC | Layered Products, i.e Products Built-up of Strata of Flat or Non-flat, e.g Cellular or Honeycomb, Form B32B 17/10238 (20130101) Use of Inorganic or Non-macromolecular Organic Substances as Compounding Ingredients C08K 3/01 (20180101) C08K 3/36 (20130101) Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 5/0092 (20130101) Heat-exchange Apparatus, Not Provided for in Another Subclass, in Which the Heat-exchange Media Do Not Come into Direct Contact F28D 20/00 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 13/18 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357729 | XU et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Rui XU (Rexford, New York); Weizhong YAN (Clifton Park, New York); Masoud ABBASZADEH (Clifton Park, New York); Matthew Christian NIELSEN (Scotia, New York) |
| ABSTRACT | An industrial asset may have monitoring nodes that generate current monitoring node values representing a current operation of the industrial asset. An abnormality detection computer may detect when a monitoring node is currently being attacked or experiencing a fault based on a current feature vector, calculated in accordance with current monitoring node values, and a detection model that includes a decision boundary. A model updater (e.g., a continuous learning model updater) may determine an update time-frame (e.g., short-term, mid-term, long-term, etc.) associated with the system based on trigger occurrence detection (e.g., associated with a time-based trigger, a performance-based trigger, an event-based trigger, etc.). The model updater may then update the detection model in accordance with the determined update time-frame (and, in some embodiments, continuous learning). |
| FILED | Friday, April 23, 2021 |
| APPL NO | 17/239054 |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 23/024 (20130101) Original (OR) Class G05B 23/027 (20130101) G05B 23/0221 (20130101) Computer Systems Based on Specific Computational Models G06N 3/08 (20130101) G06N 3/0454 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220358214 | Anderson et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| ASSIGNEE(S) | Battelle Energy Alliance, LLC (Idaho Falls, Idaho) |
| INVENTOR(S) | Matthew W. Anderson (Idaho Falls, Idaho); Matthew R. Sgambati (Rigby, Idaho); Brandon S. Biggs (Idaho Falls, Utah) |
| ABSTRACT | Human-readable (HR) code may be derived from a binary. The HR code may be configured to have statistical properties suitable for machine-learned (ML) translation. The HR code may comprise source code, intermediate code, assembly code, or the like. A machine-learned translator may be configured to translate the HR code into labels comprising semantic information pertaining to respective functions of the binary, such as a function name, role, or the like. Execution of the binary may be blocked in response to translating the HR code to a label associated with malware, such as cryptocurrency mining malware or the like. Conversely, the binary may be permitted to proceed to execution in response to determining that the translation is free from labels indicative of malware. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/308006 |
| CURRENT CPC | Electric Digital Data Processing G06F 21/56 (20130101) Original (OR) Class G06F 2221/034 (20130101) Computer Systems Based on Specific Computational Models G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220359094 | Petrie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Christian M. Petrie (Oak Ridge, Tennessee); Phillip C. Chesser (Oak Ridge, Tennessee); Benjamin R. Betzler (Oak Ridge, Tennessee); Ryan R. Dehoff (Oak Ridge, Tennessee); Kevin G. Field (Oak Ridge, Tennessee); Kurt A. Terrani (Oak Ridge, Tennessee) |
| ABSTRACT | A nuclear fuel cladding with improved thermomechanical properties is provided. The nuclear fuel cladding includes a double-walled construction having inner and outer hexagonal sidewalls. The inner sidewall and the outer sidewall are spaced apart from each other to form a cooling channel therebetween, and the inner sidewall surrounds a nuclear fuel and is spaced apart from the nuclear fuel by a small gap. Helical fins extend into the cooling channel to interconnect the inner sidewall and the outer sidewall. Resilient fingers extend toward the nuclear fuel through the small gap to comply with variations in the size of the nuclear fuel due to fabrication tolerances as well as thermal expansion and swelling of the nuclear fuel, for example UO2, when undergoing fission. The nuclear fuel cladding is formed according to an additive manufacturing process, for example laser powder bed fusion printing. |
| FILED | Monday, April 25, 2022 |
| APPL NO | 17/728327 |
| CURRENT CPC | Nuclear Reactors G21C 15/06 (20130101) Original (OR) Class G21C 15/28 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220359095 | TRUPIANO et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| ASSIGNEE(S) | Westinghouse Electric Company LLC (Cranberry Township, Pennsylvania) |
| INVENTOR(S) | Anthony G. TRUPIANO (Pittsburgh, Pennsylvania); Adana L. STANISH (Cranberry Township, Panama); Jonathan C. DURFEE (Mars, Pennsylvania); William L. BROWN (Pittsburgh, Pennsylvania) |
| ABSTRACT | A housing assembly configured to house a reactor is disclosed. The housing assembly includes a plurality of modular walls configured to surround the reactor and a passive temperature control system. The plurality of modular walls includes a first modular wall. The passive temperature control system is coupled to the first modular wall. The passive temperature control system is configured to transfer heat between the reactor and an area around the housing assembly. |
| FILED | Wednesday, May 05, 2021 |
| APPL NO | 17/308353 |
| CURRENT CPC | Nuclear Reactors G21C 15/257 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220359183 | Cooks et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Robert Graham Cooks (West Lafayette, Indiana); Zane Baird (West Lafayette, Indiana); Wen-Ping Peng (Shoufeng, Taiwan) |
| ABSTRACT | The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure. |
| FILED | Friday, July 08, 2022 |
| APPL NO | 17/860486 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 49/06 (20130101) H01J 49/10 (20130101) H01J 49/26 (20130101) H01J 49/067 (20130101) Original (OR) Class H01J 49/165 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220359778 | Rodrigues Augusto et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Andre Filipe Rodrigues Augusto (Tempe, Arizona); Apoorva Srinivasa (Beaverton, Oregon); Stuart Bowden (Tempe, Arizona) |
| ASSIGNEE(S) | Arizona Board of Regents on behalf of Arizona State University (Scottsdale, Arizona) |
| INVENTOR(S) | Andre Filipe Rodrigues Augusto (Tempe, Arizona); Apoorva Srinivasa (Beaverton, Oregon); Stuart Bowden (Tempe, Arizona) |
| ABSTRACT | Photovoltaic devices with very high breakdown voltages are described herein. Typical commercial silicon photovoltaic devices have breakdown voltages below 50-100 volts (V). Even though such devices have bypass diodes to prevent photovoltaic cells from going into breakdown, the bypass diodes have high failure rates, leading to unreliable devices. A high-efficiency silicon photovoltaic cell is provided with very high breakdown voltages. By combining a device architecture with very low surface recombination and silicon wafers with high bulk resistivity (above 10 ohms centimeter (Ω-cm)), embodiments described herein achieve breakdown voltages close to 1000 V. These photovoltaic cells with high breakdown voltages improve the reliability of photovoltaic devices, while reducing their design complexity and cost. |
| FILED | Monday, May 02, 2022 |
| APPL NO | 17/734737 |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 31/077 (20130101) H01L 31/0288 (20130101) H01L 31/0512 (20130101) Original (OR) Class H01L 31/1868 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220359875 | CHEN et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| ASSIGNEE(S) | GM GLOBAL TECHNOLOGY OPERATIONS LLC (Detroit, Michigan) |
| INVENTOR(S) | Mengyuan CHEN (Madison Heights, Michigan); Xingcheng XIAO (Troy, Michigan) |
| ABSTRACT | A solid-state electrochemical cell that cycles lithium ions. The electrochemical cell may include a solid-state electrolyte defining a first major surface and a negative electrode defining a second major surface. The electrochemical cell may also include an interfacial layer disposed between the first major surface of the solid-state electrolyte and the second major surface of the solid electrode. The interfacial layer may include an ion-conductor disposed in an organic matrix. |
| FILED | Tuesday, May 04, 2021 |
| APPL NO | 17/307664 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/62 (20130101) Original (OR) Class H01M 4/134 (20130101) H01M 10/0562 (20130101) H01M 2004/027 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220360216 | Gostein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Michael Gostein (Austin, Texas); William Stueve (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Gostein (Austin, Texas); William Stueve (Austin, Texas) |
| ABSTRACT | In one respect, disclosed is an in-situ current-voltage (I-V) measurement device for photovoltaic modules in a photovoltaic array, comprising a variable load, wherein the variable load is configured to be connected in parallel with a module, wherein the module is connected in series with at least one other module in a string, such that the module supplies current simultaneously to the string and to the variable load, and wherein the variable load is controlled by a controller, and wherein the controller is configured to shift an I-V operating point of the module, based at least upon varying the variable load. |
| FILED | Monday, May 09, 2022 |
| APPL NO | 17/739823 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 21/06 (20130101) Generation of Electric Power by Conversion of Infra-red Radiation, Visible Light or Ultraviolet Light, e.g Using Photovoltaic [PV] Modules H02S 50/10 (20141201) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 20220354778 | JOHNSTON et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Keith P. JOHNSTON (Austin, Texas); Joshua ENGSTROM (Spotswood, New Jersey); Jasmine ROWE (Austin, Texas); Alan B. WATTS (Plainsboro, New Jersey); Robert O. WILLIAMS, III (Austin, Texas) |
| ABSTRACT | The present invention includes compositions and methods for treating and delivering medicinal formulations using an inhaler. The composition includes a space filled flocculated suspension having one or more flocculated particles of one or more active agents and a hydrofluoroalkane propellant. A portion of the one or more flocculated particles is templated by the formation of hydrofluoroalkane droplets upon atomization and the templated floc compacts upon the evaporation of the hydrofluoroalkane propellant to form a porous particle for deep lung delivery. |
| FILED | Tuesday, May 17, 2022 |
| APPL NO | 17/746915 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/008 (20130101) Original (OR) Class A61K 9/0075 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354891 | WANG et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Yingxiao WANG (San Diego, California); Praopim LIMSAKUL (San Diego, California); Yiqian WU (San Diego, California) |
| ABSTRACT | In alternative embodiments, provided are compositions, including products of manufacture and kits, and methods, for engineering immune effector cells, e.g., T cells, NK cells, monocytes and/or macrophages to recognize and destroy a desired target cell, which can be a cancer cell, a dysfunctional cell, or an infected cell. |
| FILED | Thursday, July 16, 2020 |
| APPL NO | 17/627193 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Original (OR) Class A61K 38/195 (20130101) A61K 47/6803 (20170801) Peptides C07K 16/44 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355248 | Sibener et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE UNIVERSITY OF CHICAGO (Chicago, Illinois) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Steven J. Sibener (Chicago, Illinois); Michelle R. Brann (Chicago, Illinois); Stephen P. Hansknecht (Chicago, Illinois) |
| ABSTRACT | Provided are apparatus and methods for enriching and separating isotopologues or isotopes. The apparatus and methods enrich and/or separate isotopes or isotopologues present in a substantially monovelocity supersonic beam incident upon a solid surface comprising condensed forms of the isotopologues or the isotopes via the differential condensation of the different isotopologues or isotopes on the surface or the differential reflection of the different isotopologues or isotopes from the surface. |
| FILED | Monday, April 25, 2022 |
| APPL NO | 17/728453 |
| CURRENT CPC | Separation B01D 59/34 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355289 | Shtein et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Max Shtein (Ann Arbor, Michigan); Y. Eugene Shteyn (Cupertino, California); Steven Morris (Ann Arbor, Michigan); Brian lezzi (Ann Arbor, Michigan); Siddharth Borsadia (Ann Arbor, Michigan); Joanna Ciatti (Ann Arbor, Michigan); Katie Wei (Ann Arbor, Michigan) |
| ABSTRACT | Disclosed herein is are methods and apparatuses for synthesizing deposited films of compounds (e.g., organic compounds such as a pharmaceutical active ingredient or a new chemical entity) on or in a variety of substrates, where such deposited compounds the desired stability under storage conditions, ease of handling, and yet enhanced dissolution properties when used in various assays. The disclosure further relates to methods of coating substrates, such as medical or diagnostic devices, with deposited films of organic compounds, as well as film-coated substrates. |
| FILED | Monday, April 20, 2020 |
| APPL NO | 17/604919 |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/52 (20130101) B01L 3/0289 (20130101) Original (OR) Class B01L 3/5085 (20130101) B01L 2200/16 (20130101) B01L 2200/141 (20130101) B01L 2200/148 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/60 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355512 | FINI et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Arizona Board of Regents on Behalf of Arizona State University (Scottsdale, Arizona) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Elham FINI (Phoenix, Arizona); Sk Faisal KABIR (Tempe, Arizona) |
| ABSTRACT | Preparing hybrid-treated plastic particles from waste plastic includes combining waste plastic particles with bio-oil to yield a mixture, irradiating the mixture with microwave radiation to yield oil-treated plastic particles, and contacting the oil-treated plastic particles with carbon-containing nanoparticles to yield hybrid-treated plastic particles. The hybrid-treated plastic particles have a bio-oil modified surface and a coating comprising carbon-containing nanoparticles on the bio-oil modified surface of the plastic particle. In some examples, a diameter of the plastic particle is in a range between 250 m and 750 m, and a thickness of the coating is in a range of 1 nm to 20 nm. A modified binder includes an asphalt binder or a concrete binder and a multiplicity of the treated plastic particles. The modified binder typically includes 5 wt % to 25 wt % of the hybrid-treated plastic particles. |
| FILED | Thursday, November 12, 2020 |
| APPL NO | 17/775122 |
| CURRENT CPC | Preparation or Pretreatment of the Material to be Shaped; Making Granules or Preforms; Recovery of Plastics or Other Constituents of Waste Material Containing Plastics B29B 9/16 (20130101) Original (OR) Class B29B 13/08 (20130101) B29B 2009/163 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 26/26 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 7/61 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220355540 | Meenakshisundaram et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Ravi Shankar Meenakshisundaram (Aspinwall, Pennsylvania); Mohsen Tabrizi (Pittsburgh, Pennsylvania); Taylor H Ware (Richardson, Texas) |
| ABSTRACT | A four-dimensional (“4D”)-printing or 4D-additive manufacturing method for producing anisotropic macroscopic structures and/or anisotropic macroscopic materials having a plurality of voxels, comprising: providing or forming a first layer of a photocurable first liquid crystalline (LC) monomer; wherein the first layer of the first LC monomer has been provided or formed at a temperature falling within a nematic phase range of the first LC monomer; applying a magnetic field, having a first three-dimensional (“3D”) magnetic field vector with respect to an origin point of a 3D coordinate system, to the first layer of first LC monomer or one or more of the plurality of voxels within the first layer of first LC monomer for a first dwell time, to produce in alignment with the first 3D magnetic field vector a first molecular director and/or first nematic alignment vector within the first layer of first LC monomer or within each of the one or more of the plurality of voxels within the first layer of first LC monomer; exposing the first layer of first LC monomer or the one or more of the plurality of voxels within the first layer of first LC monomer to a first dose of light radiation. |
| FILED | Monday, June 22, 2020 |
| APPL NO | 17/621115 |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/129 (20170801) Original (OR) Class Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356058 | Painter et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Oskar Painter (Sierra Madre, California); Jie Luo (Pasadena, California); Michael T. Fang (Pasadena, California); Alp Sipahigil (Pasadena, California); Paul B. Dieterle (Somerville, Massachusetts); Mahmoud Kalaee (Pasadena, California); Johannes M. Fink (Klosterneuburg, Austria); Andrew J. Keller (Los Angeles, California); Gregory MacCabe (Los Angeles, California); Hengjiang Ren (Pasadena, California); Justin D. Cohen (Annandale, Virginia) |
| ABSTRACT | Embodiments described herein include systems and techniques for converting (i.e., transducing) a quantum-level (e.g., single photon) signal between the three wave forms (i.e., optical, acoustic, and microwave). A suspended crystalline structure is used at the nanometer scale to accomplish the desired behavior of the system as described in detail herein. Transducers that use a common acoustic intermediary transform optical signals to acoustic signals and vice versa as well as microwave signals to acoustic signals and vice versa. Other embodiments described herein include systems and techniques for storing a qubit in phonon memory having an extended coherence time. A suspended crystalline structure with specific geometric design is used at the nanometer scale to accomplish the desired behavior of the system. |
| FILED | Friday, July 15, 2022 |
| APPL NO | 17/866281 |
| CURRENT CPC | Microstructural Devices or Systems, e.g Micromechanical Devices B81B 3/0021 (20130101) B81B 3/0029 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 10/00 (20130101) B82Y 20/00 (20130101) B82Y 40/00 (20130101) Measurement of Mechanical Vibrations or Ultrasonic, Sonic or Infrasonic Waves G01H 11/08 (20130101) Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Static Stores G11C 13/025 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356137 | Subramaniam et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Kansas (Lawrence, Kansas); Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bala Subramaniam (Lawrence, Kansas); Anand Ramanathan (Bartlesville, Oklahoma); Yang Xiao (West Lafayette, Indiana); Arvind Varma (West Lafayette, Indiana) |
| ABSTRACT | Methods for gas-phase deoxygenation of a bio-oil are provided. In embodiments, such a method comprises exposing a bio-oil vapor comprising hydrocarbon compounds having oxygenated aromatic groups, to hydrogen gas in the presence of catalyst under conditions to induce deoxygenation of the oxygenated aromatic groups to provide a deoxygenated aromatic species, wherein the catalyst is a transition metal-incorporated mesoporous silicate having platinum deposited thereon and the transition metal is selected from Nb, W, Zr, and combinations thereof. The transition metal-incorporated mesoporous silicate catalysts are also provided. |
| FILED | Friday, June 19, 2020 |
| APPL NO | 17/621259 |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/6484 (20130101) B01J 23/6527 (20130101) B01J 29/0308 (20130101) Acyclic or Carbocyclic Compounds C07C 37/055 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357278 | Ly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victoria Ly (Santa Cruz, California); Mircea Teodorescu (Santa Cruz, California) |
| ABSTRACT | An alignment platform for use with an imaging device includes an outer stage, an inner stage disposed within the outer stage and flexibly coupled to the outer stage, and a central frame disposed within the inner stage and flexibly coupled to the inner stage. The central frame is configured to support an object being imaged. The inner stage and the central frame are movable relative to the outer stage along a first axis and the central frame is movable relative to outer stage and the inner stage along a second axis that is perpendicular to the first axis. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738262 |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Original (OR) Class G01N 21/6486 (20130101) G01N 2201/021 (20130101) G01N 2201/062 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357394 | Bhunia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Florida Research Foundation, Incorporated (Gainesville, Florida) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Swarup Bhunia (Gainesville, Florida); Christopher Vega (Gainesville, Florida); Reiner Dizon (Gainesville, Florida); Rohan Reddy Kalavakonda (Gainesville, Florida); Patanjali Sristi Lakshmiprasanna Sriramakumara (Gainesville, Florida) |
| ABSTRACT | A reconfigurable JTAG includes, in part, a core logic, a boundary scan chain cell, one or more reconfigurable blocks (RBs), and a reconfigurable block (RB) programming module. The RBs may include, in part, one or more reconfigurable boundary scan chain blocks (RBB) adapted to couple the boundary scan chain cell to the core logic and to input/output (I/O) ports of the reconfigurable JTAG. The RBs may also include, in part, one or more additional reconfigurable logic (ARL) blocks to provide enhanced logic for locking operations. The RB programmable module may communicate with a memory storing data for configuring the RBBs and ARLs. The RB programming module may configure the RBBs and ARLs based at least in part on the data stored in the memory to disable access to the I/O ports of the JTAG. The RB programming module may configure the RBBs to encrypt the I/O ports in accordance with a cipher algorithm. The RB programming module may also configure the RBBs and ARLs to compare a counter's count to a predefined time and lock the I/O ports after an expiration of the predefined time. |
| FILED | Thursday, April 28, 2022 |
| APPL NO | 17/661232 |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 31/31713 (20130101) G01R 31/318536 (20130101) Original (OR) Class G01R 31/318555 (20130101) G01R 31/318588 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220357566 | Ly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Victoria Ly (Santa Cruz, California); Pierre Baudin (Santa Cruz, California); Yohei Rosen (Santa Cruz, California); Pat Pansodtee (Santa Cruz, California); Kateryna Voitiuk (Santa Cruz, California); David Haussler (Santa Cruz, California); Mircea Teodorescu (Santa Cruz, California) |
| ABSTRACT | An imaging device includes an alignment platform configured to hold a cell culture plate having a plurality of wells and an imaging assembly including a plurality of imaging units, each of which is configured to image one well of the plurality of wells. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738239 |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) G02B 21/367 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
20220357631 — AN OPTICAL SWITCH DEVICE CONFIGURED FOR TOPOLOGICAL LIGHT STEERING AND RELATED METHODS
| US 20220357631 | Feng et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Liang Feng (Wynnewood, Pennsylvania); Han Zhao (Philadelphia, Pennsylvania) |
| ABSTRACT | An optical switch device and a related method for defining a topological light transport channel in a photonic lattice are provided. An exemplary optical switch device includes a photonic lattice including a photonic topological microring array comprising a plurality of site rings coupled via a plurality of anti-resonant link rings, a plurality of input light ports and a plurality of output light ports located at the plurality of site rings, wherein the plurality of input light ports and the plurality of output light ports are respectively connected by a plurality of topological light transport channels. The optical switch device is further configured such that each of the topological light transport channels is defined by a gain domain area that is produced by a corresponding patterned optical pumping beam emitted onto the photonic topological microring array. |
| FILED | Monday, September 14, 2020 |
| APPL NO | 17/642396 |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/313 (20130101) Original (OR) Class G02F 2202/102 (20130101) G02F 2203/24 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220358904 | Mandel et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Research Foundation of the City University of New York (New York, New York) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Michael Mandel (Brooklyn, New York); Soumi Maiti (Brooklyn, New York) |
| ABSTRACT | A method for Parametric resynthesis (PR) producing an audible signal. A degraded audio signal is received which includes a distorted target audio signal. A prediction model predicts parameters of the audible signal from the degraded signal. The prediction model was trained to minimize a loss function between the target audio signal and the predicted audible signal. The predicted parameters are provided to a waveform generator which synthesizes the audible signal. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 17/441063 |
| CURRENT CPC | Speech Analysis or Synthesis; Speech Recognition; Speech or Voice Processing; Speech or Audio Coding or Decoding G10L 13/047 (20130101) Original (OR) Class G10L 21/0264 (20130101) G10L 25/18 (20130101) G10L 25/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220359157 | WELSH et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Malachite Technologies, Inc. (San Francisco, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Alexander David WELSH (San Francisco, California); Robert WEISS (San Francisco, California); David BROWN (San Francisco, California); Nicholas WHITE (Manchester, Massachusetts) |
| ABSTRACT | A treatment system and process includes a ribbon beam ion source that is configured to implant ions into a product to modify a portion of the product; multiple means of controlling the temperature of the product; the means including radiative conduction, gas conduction to a heatsink by means of a gas cushion, adjustment of the ion beam density at the product, adjustment of the ion beam intensity at the product and ion beam acceleration parameters, and adjustment of the ion dose to the product b; and a product movement system configured to move the product through the treatment system past the ribbon beam ion source. The treatment system further includes a system controller configured to control at least one the following: the gas cushion system, the ribbon beam ion source, the temperature control system, the heatsink, and the product movement system. |
| FILED | Thursday, May 05, 2022 |
| APPL NO | 17/737079 |
| CURRENT CPC | Electric Discharge Tubes or Discharge Lamps H01J 37/08 (20130101) H01J 37/3171 (20130101) Original (OR) Class H01J 2237/24585 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220360703 | Ly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Victoria Ly (Santa Cruz, California); Pierre Baudin (Santa Cruz, California); Pat Pansodtee (Santa Cruz, California); Erik Jung (Santa Cruz, California); Robert Currie (Santa Cruz, California); David Haussler (Santa Cruz, California); Mircea Teodorescu (Santa Cruz, California) |
| ABSTRACT | An imaging system includes an imaging device having a holder configured to hold a cell culture plate with a plurality of wells. The imaging device also includes an imaging assembly having a plurality of imaging units, each of which is configured to image one well of the plurality of wells. The imaging system also includes a storage platform in communication with the imaging device configured to receive a plurality of images from the imaging device. The system further includes a computer in communication with the imaging device and the storage platform. The computer is configured to control the imaging device and to display at least one image of the plurality of images. |
| FILED | Friday, May 06, 2022 |
| APPL NO | 17/738251 |
| CURRENT CPC | Apparatus for Enzymology or Microbiology; C12M 25/06 (20130101) Optical Elements, Systems, or Apparatus G02B 21/365 (20130101) Image Data Processing or Generation, in General G06T 7/571 (20170101) G06T 2207/10056 (20130101) G06T 2207/10148 (20130101) G06T 2207/30024 (20130101) G06T 2207/30072 (20130101) Pictorial Communication, e.g Television H04N 5/247 (20130101) H04N 5/265 (20130101) H04N 5/23203 (20130101) Original (OR) Class H04N 5/23216 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220360758 | Redden |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Blue River Technology Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lee Kamp Redden (Palo Alto, California) |
| ABSTRACT | Described are methods for identifying the in-field positions of plant features on a plant by plant basis. These positions are determined based on images captured as a vehicle (e.g., tractor, sprayer, etc.) including one or more cameras travels through the field along a row of crops. The in-field positions of the plant features are useful for a variety of purposes including, for example, generating three-dimensional data models of plants growing in the field, assessing plant growth and phenotypic features, determining what kinds of treatments to apply including both where to apply the treatments and how much, determining whether to remove weeds or other undesirable plants, and so on. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/853925 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6277 (20130101) Image Data Processing or Generation, in General G06T 7/593 (20170101) Image or Video Recognition or Understanding G06V 20/38 (20220101) Pictorial Communication, e.g Television H04N 13/128 (20180501) H04N 13/204 (20180501) Original (OR) Class H04N 13/239 (20180501) H04N 13/243 (20180501) H04N 13/271 (20180501) H04N 2013/0081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220360847 | Chukoskie et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leanne Chukoskie (San Diego, California); Pamela Cosman (La Jolla, California); Pranav Venuprasad (Framingham, Massachusetts); Anurag Paul (Sunnyvale, California); Tushar Dobhal (Bentonville, Arkansas); Tu Nguyen (Tay Ninh Province, Viet Nam); Andrew Gilman (Tauranga, New Zealand) |
| ABSTRACT | Systems, devices, and methods are disclosed for characterizing joint attention. A method includes dynamically obtaining video streams of participants; dynamically obtaining gaze streams; dynamically providing a cue to the participants to view the object; dynamically detecting a joint gaze based on the gaze streams focusing on the object over a time interval; and dynamically providing feedback based on detecting the joint gaze. |
| FILED | Thursday, June 25, 2020 |
| APPL NO | 17/620082 |
| CURRENT CPC | Electric Digital Data Processing G06F 3/013 (20130101) Pictorial Communication, e.g Television H04N 21/44218 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 20220354896 | NASONKIN et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | LINEAGE CELL THERAPEUTICS, INC. (Carlsbad, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Igor NASONKIN (Carlsbad, California); Ratnesh SINGH (Carlsbad, California); Francois BINETTE (Carlsbad, California) |
| ABSTRACT | Presented herein are compositions and methods for generating stem cell derived retinal tissue and isolated retinal progenitor cells for use in the treatment of retinal degenerative diseases and disorders. |
| FILED | Tuesday, April 28, 2020 |
| APPL NO | 17/606990 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 35/30 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 27/02 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0621 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220358645 | Modayur |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BSOLUTIONS, INC. (Seattle, Washington) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bharath Modayur (Seattle, Washington) |
| ABSTRACT | A system for facilitating developmental monitoring of children comprises one or more processors and one or more hardware storage devices storing instructions that are executable by the one or more processors to configure the system to (i) access a set of image data depicting a subject, (ii) extract a set of features from the set of image data, the set of features indicating one or more body characteristics of the subject as represented in the set of image data, and (iii) determine a set of developmental metrics for the subject based upon the set of features, the set of developmental metrics being indicative of a developmental state for the subject. |
| FILED | Tuesday, May 03, 2022 |
| APPL NO | 17/735650 |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 7/0012 (20130101) Original (OR) Class G06T 2207/30004 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 15/00 (20180101) G16H 40/67 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220359857 | Jang |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Global Graphene Group, Inc. (Dayton, Ohio) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Bor Z. Jang (Centerville, Ohio) |
| ABSTRACT | The disclosure provides a method of prelithiating an anode for a lithium-ion cell, the method comprising: (a) providing a pre-fabricated anode comprising an anode active material; (b) prelithiating the pre-fabricated anode by exposing the anode to a lithium source and an electrolyte solution, comprising a lithium salt dissolved in a liquid solvent, to enable lithium ions to intercalate into the anode active material until a level of lithium interaction from 5% to 100% of the maximum lithium storage capacity is achieved to form a prelithiated anode; and (c) introducing a protective polymer onto the prelithiated anode to prevent exposure of the prelithiated anode active material to the open air or into the anode to bond the prelithiated anode active material or to improve a structural integrity of the prelithiated anode, wherein the protective polymer has a lithium-ion conductivity from 10−8 S/cm to 5×10−2 S/cm at room temperature. |
| FILED | Thursday, April 29, 2021 |
| APPL NO | 17/244441 |
| CURRENT CPC | Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/13 (20130101) H01M 4/134 (20130101) H01M 4/139 (20130101) H01M 4/386 (20130101) H01M 4/0459 (20130101) Original (OR) Class H01M 4/523 (20130101) H01M 4/582 (20130101) H01M 4/625 (20130101) H01M 4/628 (20130101) H01M 4/1395 (20130101) H01M 10/0525 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220360758 | Redden |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Blue River Technology Inc. (Sunnyvale, California) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Lee Kamp Redden (Palo Alto, California) |
| ABSTRACT | Described are methods for identifying the in-field positions of plant features on a plant by plant basis. These positions are determined based on images captured as a vehicle (e.g., tractor, sprayer, etc.) including one or more cameras travels through the field along a row of crops. The in-field positions of the plant features are useful for a variety of purposes including, for example, generating three-dimensional data models of plants growing in the field, assessing plant growth and phenotypic features, determining what kinds of treatments to apply including both where to apply the treatments and how much, determining whether to remove weeds or other undesirable plants, and so on. |
| FILED | Thursday, June 30, 2022 |
| APPL NO | 17/853925 |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6277 (20130101) Image Data Processing or Generation, in General G06T 7/593 (20170101) Image or Video Recognition or Understanding G06V 20/38 (20220101) Pictorial Communication, e.g Television H04N 13/128 (20180501) H04N 13/204 (20180501) Original (OR) Class H04N 13/239 (20180501) H04N 13/243 (20180501) H04N 13/271 (20180501) H04N 2013/0081 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 20220354125 | Morra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Idaho (Moscow, Idaho) |
| ASSIGNEE(S) | University of Idaho (Moscow, Idaho) |
| INVENTOR(S) | Matthew J. Morra (Moscow, Idaho); Inna E. Popova (Moscow, Idaho); Jeremiah Dubie (Moscow, Idaho) |
| ABSTRACT | Disclosed are embodiments of a method of using mustard meal or mustard meal extract. Certain embodiments concern controlling vegetable sprouting, such as potato sprouting. Vegetables, such as potatoes, may be exposed to products resulting from mustard meal, or an extract thereof, contacting water. Other embodiments concern a process for controlling plant pests, such as insects, nematodes, fungi, weeds, and combinations thereof, with specific embodiments being particularly useful for weed suppression. Certain embodiments comprise extracting glucosinolates from plant material, or processed plant material, selected from the family Brassicaceae, particularly from the genera Brassica and Sinapis. Extracted glucosinolates can be hydrolyzed to form active compounds, or alternatively, they can be hydrolyzed in situ, by simultaneously or sequentially applying myrosinase. The extract can be applied to plants, to the soil adjacent to the plant. |
| FILED | Monday, December 13, 2021 |
| APPL NO | 17/549491 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 25/02 (20130101) A01N 65/00 (20130101) Original (OR) Class A01N 65/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220354905 | Aroian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF MASSACHUSETTS (Boston, Massachusetts) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Raffi Van Aroian (Worcester, Massachusetts); Gary R. Ostroff (Worcester, Massachusetts) |
| ABSTRACT | Compositions and methods for treating or reducing the severity of occurrence of a parasitic worm or helminth infection in a subject are described. The methods include administering to the subject a therapeutically effective amount of a composition comprising isolated native, bioactive nematicidal crystals formed from a single type of nematicidal crystal protein. The isolated native, bioactive nematicidal crystals are substantially free of any bacterial spores or host bacterial proteins, other than nematicidal crystal protein in the form of a crystal. Methods for making isolated native, bioactive nematicidal crystals are also described. The crystal proteins may be full length, truncated, variant, or sub-variant Cry proteins. Examples of crystal proteins include Cry5B, Cry21, Cry14A, Cry6A, and Cry13A. |
| FILED | Tuesday, April 26, 2022 |
| APPL NO | 17/729785 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/48 (20130101) A61K 35/741 (20130101) Original (OR) Class A61K 38/164 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220356492 | Silver et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kristopher Silver (Manhattan, Kansas); Yoonseong Park (Manhattan, Kansas) |
| ABSTRACT | Nucleic acid delivery vehicles for delivering nucleic acid, e.g., for RNAi to cells that are typically refractory to RNAi by using extracellular vesicles (EVs) from cultured beetle cells as delivery vehicles. Instead of using high levels of long dsRNA and transfection reagents to accomplish suppression of an mRNA target in cells that don't respond to treatment with naked dsRNA, this approach applies the dsRNA to cultured beetle cells, collects nucleic-acid loaded EVs from the culture, then treats our target cells with the intracellularly loaded EVs, which results in significant enhancement of the RNAi response and greater suppression of transcript levels. |
| FILED | Friday, August 14, 2020 |
| APPL NO | 17/635036 |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 63/60 (20200101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) Original (OR) Class C12N 15/113 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 20220355630 | Shiu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Leung Man Shiu (Gaithersburg, Maryland); Edward F. Houston (Bristow, Virginia); Anthony B. Taylor (Stafford, Virginia); Tuyen Thanh Nguyen (Fairfax, Virginia); Scott R. Bombaugh (Burke, Virginia) |
| ABSTRACT | This disclosure relates to systems and methods of towing, hitching, and connecting devices. In particular, this disclosure relates to tow devices, hitches, and connections for towing item containers behind vehicles, both autonomous and manually guided. |
| FILED | Monday, July 25, 2022 |
| APPL NO | 17/814810 |
| CURRENT CPC | Vehicle Connections B60D 1/14 (20130101) Original (OR) Class B60D 1/52 (20130101) B60D 2001/001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 20220358520 | Dearing et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Stephen M. Dearing (Herndon, Virginia); Kuldip K. Goyal (Alexandria, Virginia); Gary C. Reblin (Falls Church, Virginia); Margaret L. Choiniere (Gainesville, Virginia) |
| ABSTRACT | Systems, methods and apparatus are disclosed for providing content associated with an information item on a distribution item using a computing device. In one aspect a method includes identifying an image of an information item on a distribution item. The method further includes processing, in a processor the image, to generate a data item determined by the information item. The method further includes decoding the data item to determine a set of attributes of the distribution item. The method further includes retrieving content associated with the distribution item using at least one of the attributes in the set of attributes. The method further includes delivering content associated with the distribution item. |
| FILED | Friday, July 22, 2022 |
| APPL NO | 17/814467 |
| CURRENT CPC | Postal Sorting; Sorting Individual Articles, or Bulk Material Fit to be Sorted Piece-meal, e.g by Picking B07C 3/18 (20130101) B07C 2301/0066 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 30/02 (20130101) Original (OR) Class G06Q 30/0601 (20130101) G06Q 50/32 (20130101) G06Q 50/184 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of the Interior (DOI)
| US 20220356229 | WESTENDORF et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AbCellera Biologics Inc. (Vancouver, Canada); The United States of America, as represented by the Secretary, Department of Health and Human Svcs. (Bethesda, Maryland) |
| ASSIGNEE(S) | AbCellera Biologics Inc. (Vancouver, Canada); The United States of America, as represented by the Secretary, Department of Health and Human Svcs. (Bethesda, Maryland) |
| INVENTOR(S) | Kathryn WESTENDORF (Vancouver, Canada); Stefanie ZENTELIS (Vancouver, Canada); Krithika MUTHURAMAN (Toronto, Canada); Kevin JEPSON (Vancouver, Canada); Ester FALCONER (Vancouver, Canada); John MASCOLA (Bethesda, Maryland); Barney GRAHAM (Bethesda, Maryland); Kizzmekia CORBETT (Bethesda, Maryland); Julie LEDGERWOOD (Bethesda, Maryland); Lingshu WANG (Bethesda, Maryland); Olubukola ABIONA (Bethesda, Maryland); Wei SHI (Bethesda, Maryland); Wing-pui KONG (Bethesda, Maryland); Yi ZHANG (Bethesda, Maryland); Bryan Edward JONES (San Diego, California); Denisa FOSTER (San Diego, California); Julian DAVIES (La Jolla, California); Qing CHAI (San Diego, California); Christopher Carl FRYE (Bargersville, Indiana); Ganapathy GOPALRATHNAM (Fishers, Indiana); Jörg HENDLE (San Diego, California); John Michael SAUDER (Carlsbad, California); Jeffrey Streetman BOYLES (Indianapolis, Indiana); Anna PUSTILNIK (San Diego, California) |
| ABSTRACT | Antibodies that bind SARS-CoV Spike protein, SARS-CoV-2 Spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2. |
| FILED | Thursday, March 04, 2021 |
| APPL NO | 17/192243 |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6803 (20170801) A61K 47/6841 (20170801) A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/14 (20180101) Peptides C07K 16/10 (20130101) Original (OR) Class C07K 2317/34 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/56983 (20130101) G01N 2333/165 (20130101) G01N 2800/26 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Environmental Protection Agency (EPA)
| US 20220355353 | Scheckel et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States Government, as represented by the Administrator of the U.S. EPA (Washington, District of Columbia) |
| ASSIGNEE(S) | |
| INVENTOR(S) | Kirk Gerald Scheckel (Cincinnati, Ohio); Ranju R. Karna (Clinton, Mississippi); Charles R. Partridge (Commerce City, Colorado); Karen D. Bradham (Apex, North Carolina); David James Thomas (Chapel Hill, North Carolina); Matthew R. Noerpel (Cincinnati, Ohio); Jennifer Lynn Goetz (Petersburg, Kentucky); Todd Peter Luxton (Cincinnati, Ohio); Tyler Dale Sowers (Apex, North Carolina) |
| ABSTRACT | Methods and systems are provided for treating a contaminated environmental medium. In one example, the treatment includes adding a first jarosite-group mineral to the contaminated environmental medium to form a wet mixture under a set of conditions. The set of conditions is maintained over a duration of time to expedite precipitation of a second jarosite-group mineral, the second jarosite-group mineral incorporating contaminant cations and contaminant anions into a structure of the second jarosite-group mineral. The first jarosite-group mineral is added in situ at a contamination site. |
| FILED | Thursday, July 21, 2022 |
| APPL NO | 17/814172 |
| CURRENT CPC | Reclamation of Contaminated Soil B09C 1/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 20220354415 | Zhang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The General Hospital Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | The General Hospital Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Quan Zhang (Winchester, Massachusetts); Gary Strangman (Boxford, Massachusetts) |
| ABSTRACT | A system and a method is provided for assessing motion of a biological tissue of a subject including one or more superficial biological layers and a targeted biological layer. An optical perturbation is introduced within the one or more superficial biological layers but not within the targeted biological layer. A set of optical signal data is acquired preceding, during, or following the optical perturbation and, using the set of optical signal data, a set of optical characteristics is determined that is representative of light transiting the biological layers. Using the set of optical characteristics and a model of the biological layers, a target optical signal consistent with a target biological layer is separated and a movement of the desired biological tissue is determined using the target optical signal. |
| FILED | Tuesday, July 12, 2022 |
| APPL NO | 17/863002 |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) A61B 5/4064 (20130101) Original (OR) Class A61B 5/6814 (20130101) A61B 5/14553 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
How To Use This Page
THE FEDINVENT PATENT APPLICATION DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Thursday, November 10, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week's taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer-funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract is presented as it appears on the patent.
FILED
The date the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that the more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/fedinvent-applications-20221110.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page