FedInvent™ Patents
Patent Details for Tuesday, February 01, 2022
This page was updated on Thursday, February 03, 2022 at 01:47 AM GMT
Department of Health and Human Services (HHS)
| US 11234607 | Barlow et al. |
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| FUNDED BY |
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| APPLICANT(S) | Steven M. Barlow (Lawrence, Kansas); David L. Stalling (Shawnee, Kansas); Kenneth Aron (Shawnee, Kansas) |
| ASSIGNEE(S) | Innara Health, Inc. (Olathe, Kansas); University of Kansas (Lawrence, Kansas) |
| INVENTOR(S) | Steven M. Barlow (Lawrence, Kansas); David L. Stalling (Shawnee, Kansas); Kenneth Aron (Shawnee, Kansas) |
| ABSTRACT | The present invention relates to methods of using a therapeutic system. In particular, the present invention relates to procedures and methods of using a system having hardware, software, and appliance components for assessing and entraining a non-nutritive suck (NNS) pattern in a patient. The methods include configuring the hardware and software systems to receive data from an orofacial stimulation appliance and to generate a precise therapeutic pulse profile that is actuated as a tactile stimulus. The methods also include collecting data using the orofacial stimulation appliance and delivering the tactile stimulus via the orofacial stimulation appliance to entrain an organized NNS pattern. |
| FILED | Thursday, April 26, 2012 |
| APPL NO | 13/457154 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/038 (20130101) Original (OR) Class A61B 5/486 (20130101) A61B 5/682 (20130101) A61B 5/6896 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234627 | Seymour et al. |
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| FUNDED BY |
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| APPLICANT(S) | NeuroNexus Technologies, Inc. (Ann Arbor, Michigan) |
| ASSIGNEE(S) | NeuroNexus Technologies, Inc. (Ann Arbor, Michigan) |
| INVENTOR(S) | John P. Seymour (Ann Arbor, Michigan); Jongeun Jeon (Ann Arbor, Michigan); Nicholas Hewitt (Chelsea, Michigan); Abeer Khurram (Ypsilanti, Michigan) |
| ABSTRACT | An optical electrode having a plurality of electrodes, including a recording electrode having a roughened surface and an optical light source configured to emit light, wherein at least a portion of the light impinges on the recording electrode. Also disclosed are methods of producing an optical electrode and an opto-electronic neural interface system. |
| FILED | Friday, February 15, 2019 |
| APPL NO | 16/277334 |
| ART UNIT | 3794 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/24 (20210101) Original (OR) Class A61B 5/6847 (20130101) A61B 5/6868 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0534 (20130101) A61N 5/0622 (20130101) A61N 2005/0612 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49826 (20150115) Y10T 29/49886 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234637 | Kayyali et al. |
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| FUNDED BY |
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| APPLICANT(S) | Cleveland Medical Devices Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | Cleveland Medical Devices Inc. (Cleveland, Ohio) |
| INVENTOR(S) | Hani Kayyali (Shaker Heights, Ohio); Craig A. Frederick (Solon, Ohio); Christian Martin (Eden, North Carolina); Robert N. Schmidt (Ft. Myers, Florida); Brian Kolkowski (Leroy, Ohio) |
| ABSTRACT | The present invention provides a method of conducting a sleep analysis by collecting physiologic and kinetic data from a subject, preferably via a wireless in-home data acquisition system, while the subject attempts to sleep at home. The sleep analysis, including clinical and research sleep studies and cardiorespiratory studies, can be used in the diagnosis of sleeping disorders and other diseases or conditions with sleep signatures, such as Parkinson's, epilepsy, chronic heart failure, chronic obstructive pulmonary disorder, or other neurological, cardiac, pulmonary, or muscular disorders. The method of the present invention can also be used to determine if environmental factors at the subject's home are preventing restorative sleep. |
| FILED | Monday, June 14, 2021 |
| APPL NO | 17/346640 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0022 (20130101) A61B 5/0077 (20130101) A61B 5/085 (20130101) A61B 5/087 (20130101) A61B 5/0205 (20130101) A61B 5/318 (20210101) A61B 5/369 (20210101) A61B 5/389 (20210101) A61B 5/398 (20210101) A61B 5/1135 (20130101) A61B 5/4815 (20130101) Original (OR) Class A61B 5/6814 (20130101) A61B 5/6828 (20130101) A61B 5/14552 (20130101) A61B 2505/07 (20130101) A61B 2560/0242 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234657 | Fleming et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rhode Island Hospital (Providence, Rhode Island); Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | Rhode Island Hospital (Providence, Rhode Island); Children's Medical Center Corporation (Boston, Massachusetts) |
| INVENTOR(S) | Braden C. Fleming (East Greenwich, Rhode Island); Martha M. Murray (Sherborn, Massachusetts) |
| ABSTRACT | The current subject matter provides a tool for evaluating the risk of failure or the likelihood of success of surgery of healing ligaments and tendons in the body. In some embodiments, a region of a scan comprising one or more of an anterior cruciate ligament (ACL) or an ACL graft can be defined. A magnetic resonance (MR) imaging data set can be obtained. MR parameters characterizing a size and a quality of the ACL or ACL graft can be derived using the MR data. The MR parameters can be used as inputs to a predictive model. A score characterizing a likelihood of failure of the ACL or ACL graft in a human patient can be generated using the predictive model. |
| FILED | Tuesday, May 01, 2018 |
| APPL NO | 16/609737 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/055 (20130101) A61B 5/4533 (20130101) A61B 5/4585 (20130101) A61B 5/4851 (20130101) A61B 5/7275 (20130101) Original (OR) Class Measuring Electric Variables; Measuring Magnetic Variables G01R 33/5608 (20130101) Image Data Processing or Generation, in General G06T 7/0016 (20130101) G06T 7/62 (20170101) G06T 7/174 (20170101) G06T 11/005 (20130101) G06T 11/008 (20130101) G06T 2207/10088 (20130101) G06T 2207/30052 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 50/30 (20180101) G16H 50/50 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234673 | Fatemi et al. |
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| FUNDED BY |
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| APPLICANT(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| ASSIGNEE(S) | Mayo Foundation for Medical Education and Research (Rochester, Minnesota) |
| INVENTOR(S) | Mostafa Fatemi (Rochester, Minnesota); Mahdi Bayat (Rochester, Minnesota); Alireza Nabavizadehrafsanjani (Bronx, New York); Azra Alizad (Rochester, Minnesota) |
| ABSTRACT | Methodology, with a programmable-processor imaging system, for control and determination of breast lesion viscoelastic properties with the use of a creep-like test. Two dimensional reconstruction maps are used for different parameters of a linear viscoelastic model. Description of different aspects of the test used on live subjects and suitability of a 1-D inversion model in capturing different viscoelasticity parameters. An automated methodology for the selection of a region of interest derived only from the appearance of the breast lesion on pre-compressed B-mode images. Based on the ROI and estimated viscoelasticity parameters, contrast values are determined that facilitate the enhanced differentiation of breast mass. Employing the methodology in a large group of patients provides better understanding of variations of different viscoelasticity parameters in different types of breast lesion and helps to identify new biomarkers for enhanced differentiation of benign from malignant cases. |
| FILED | Tuesday, October 23, 2018 |
| APPL NO | 16/167791 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 8/085 (20130101) Original (OR) Class A61B 8/403 (20130101) A61B 8/463 (20130101) A61B 8/466 (20130101) A61B 8/485 (20130101) A61B 8/0825 (20130101) A61B 8/4209 (20130101) A61B 8/4281 (20130101) A61B 8/5223 (20130101) A61B 8/5253 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234681 | Jay-Russell et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Michele T. Jay-Russell (Davis, California); Esteban Soto Martinez (Davis, California); Elizabeth Antaki-Zukoski (Davis, California); Christopher Zukoski (Davis, California) |
| ABSTRACT | Provided are fish tank effluent sampling systems, e.g., for use in recirculating aquaponics systems, methods of using same for sampling effluent, and kits for assembling such an effluent sampling system. |
| FILED | Thursday, February 14, 2019 |
| APPL NO | 16/276071 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Horticulture; Cultivation of Vegetables, Flowers, Rice, Fruit, Vines, Hops or Seaweed; Forestry; Watering A01G 31/02 (20130101) A01G 2031/006 (20130101) Animal Husbandry; Care of Birds, Fishes, Insects; Fishing; Rearing or Breeding Animals, Not Otherwise Provided For; New Breeds of Animals A01K 63/10 (20170101) A01K 63/045 (20130101) Diagnosis; Surgery; Identification A61B 10/0038 (20130101) Original (OR) Class A61B 2503/40 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 3/327 (20130101) C02F 2001/007 (20130101) C02F 2103/20 (20130101) C02F 2201/005 (20130101) C02F 2203/006 (20130101) C02F 2301/046 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234751 | Rollins et al. |
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| FUNDED BY |
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| APPLICANT(S) | Case Western Reserve University (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Andrew M. Rollins (Cleveland Heights, Ohio); Christine P. Fleming (Bronx, New York) |
| ABSTRACT | Systems, methods, and other embodiments associated with characterizing Radio Frequency Ablation (RFA) lesions using Optical Coherence Tomography (OCT) are described. One example method includes acquiring an OCT signal from a Region Of Interest (ROI) in an ablated material. The example method may also include determining whether a lesion was formed by the ablation by analyzing optical properties of the ROI as recorded in the OCT signal. |
| FILED | Wednesday, January 31, 2018 |
| APPL NO | 15/884604 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0066 (20130101) A61B 5/6852 (20130101) A61B 18/02 (20130101) A61B 18/12 (20130101) Original (OR) Class A61B 18/20 (20130101) A61B 18/1492 (20130101) A61B 2017/00243 (20130101) A61B 2018/00351 (20130101) A61B 2018/00702 (20130101) A61B 2090/3735 (20160201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234896 | Lampe et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | The Trustees of the University of Pennsylvania (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Joshua Lampe (Jenkintown, Pennsylvania); Lance Becker (Philadelphia, Pennsylvania) |
| ABSTRACT | Devices and methods for blood flow enhancement and hemodynamic power monitoring are provided. A blood flow enhancement device includes a pump system configured to be coupled to a central vasculature of a subject during cardiopulmonary resuscitation (CPR). The pump system includes a pumping mechanism configured to increase forward blood flow generated during the CPR while substantially limiting backward blood flow generated during the CPR. The pumping mechanism being operated concurrently with the CPR. The hemodynamic power monitor is configured to control a chest compression device and an active valve. |
| FILED | Thursday, October 17, 2013 |
| APPL NO | 14/436250 |
| ART UNIT | 3791 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/026 (20130101) A61B 5/0215 (20130101) A61B 5/02028 (20130101) A61B 5/02158 (20130101) Physical Therapy Apparatus, e.g Devices for Locating or Stimulating Reflex Points in the Body; Artificial Respiration; Massage; Bathing Devices for Special Therapeutic or Hygienic Purposes or Specific Parts of the Body A61H 31/005 (20130101) Original (OR) Class A61H 31/006 (20130101) A61H 2230/04 (20130101) A61H 2230/255 (20130101) A61H 2230/305 (20130101) Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 60/40 (20210101) A61M 60/50 (20210101) A61M 60/122 (20210101) A61M 60/135 (20210101) A61M 60/148 (20210101) A61M 60/205 (20210101) A61M 60/274 (20210101) A61M 60/414 (20210101) A61M 60/892 (20210101) A61M 60/894 (20210101) A61M 2205/3334 (20130101) A61M 2205/3358 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 7/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234953 | Veech et al. |
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| FUNDED BY |
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| APPLICANT(S) | TDELTAS LIMITED (Thame, United Kingdom); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| ASSIGNEE(S) | TDELTAS LIMITED (Thame, United Kingdom); THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (Bethesda, Maryland) |
| INVENTOR(S) | Richard Lewis Veech (Rockville, Maryland); Kieran Clarke (Oxford, United Kingdom) |
| ABSTRACT | Described herein is the surprising discovery that ketone bodies protect cell and tissues from ionizing radiation. Based on this finding, methods of protecting animal tissue and cells from damage caused by radiation exposure are disclosed which include, contacting the tissue with a therapeutically effective amount of an agent including at least one ketone ester, thereby protecting the tissue from radiation damage. Ketone esters can be used to minimize, reduce and/or prevent tissue damage following intentional and accidental radiation exposure, as well as increasing the therapeutic efficacy of radiation therapies by protecting non-target tissue from incidental radiation damage. |
| FILED | Monday, October 07, 2019 |
| APPL NO | 16/594431 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/22 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234966 | Buynak et al. |
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| FUNDED BY |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas); University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas); University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | John D. Buynak (Dallas, Texas); Noora M. S. A. Al-Kharji (Richardson, Texas); Weirui Chai (Chicago, Illinois); Thu Q. Nguyen (North Richland Hills, Texas); Maha Alqurafi (Dallas, Texas); Kyle Rohde (Orlando, Florida); Rashmi Gupta (Lake Mary, Florida) |
| ABSTRACT | The present invention includes a composition, method of making and method of using a novel C5-substituted carbapenem antibiotic of formula 1: R1 is H or CH3 R2 is not H, and is CH3, or C1-C6 straight chain, or branched alkyl, or C3-C6 cycloalkyl group, or unsaturated alkenyl, including C═CH2; R3 is H, CH3, or a C1-C6 alkyl or cycloalkyl group, a heteroatom-substituted alkyl; and R4 is a C1 to C6 alkyl, or substituted alkyl group, especially including substituents which possess positive charge, or a hydroxyl group; or R4 is an SRa, where Ra is an unsubstituted C1 to C6 alkyl group, a substituted C1 to C6 alkyl group, or a functional group that is positively charged, or which bears a positive charge when in aqueous solution at pH 7; or R4 is a CH2ORb, where Rb=C1 to C6 alkyl or substituted alkyl groups, substituted or unsubstituted aryl, or a heteroaryl groups. |
| FILED | Thursday, May 21, 2020 |
| APPL NO | 16/879892 |
| ART UNIT | 1624 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/407 (20130101) Original (OR) Class A61K 45/06 (20130101) Heterocyclic Compounds C07D 477/00 (20130101) C07D 477/04 (20130101) C07D 477/06 (20130101) C07D 477/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234978 | Wise et al. |
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| FUNDED BY |
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| APPLICANT(S) | Southern Methodist University (Dallas, Texas) |
| ASSIGNEE(S) | Southern Methodist University (Dallas, Texas) |
| INVENTOR(S) | John G. Wise (Dallas, Texas); Pia D. Vogel (Dallas, Texas); Frances K. Brewer (Waxahachie, Texas); Courtney A. Follit (Dallas, Texas) |
| ABSTRACT | The present disclosure provides a method of treating a subject that is resistant to one or more drugs by identifying a subject having one or more drug resistant cells; administering to the subject a pharmaceutically effective amount of an inhibitor compound, and contacting one or more drug resistant cells with the inhibitor compound to reduce the export of the inhibitor compound from the one or more drug resistant tumor cells and to block the transport of drug(s) from the one or more drug resistant cells. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/584121 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/352 (20130101) A61K 31/353 (20130101) A61K 31/4196 (20130101) A61K 31/4525 (20130101) A61K 31/5025 (20130101) Original (OR) Class A61K 45/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
11234990 — Methods and compositions related to glucocorticoid receptor antagonists and breast cancer
| US 11234990 | Pan et al. |
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| FUNDED BY |
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| APPLICANT(S) | The University of Chicago (Chicago, Illinois) |
| ASSIGNEE(S) | The University of Chicago (Chicago, Illinois) |
| INVENTOR(S) | Deng Pan (Chicago, Illinois); Masha Kocherginsky (Chicago, Illinois); Suzanne D. Conzen (Park Ridge, Illinois) |
| ABSTRACT | Embodiments of the invention are directed to methods of determining the prognosis of a breast cancer patient by evaluating the activity of the glucocorticoid receptor in tumor cells. Other embodiment include methods of treating breast cancer cells, particularly, chemo-resistant cells, with a glucocorticoid receptor antagonist and an anticancer agent or compound. |
| FILED | Tuesday, October 08, 2019 |
| APPL NO | 16/596342 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Containers Specially Adapted for Medical or Pharmaceutical Purposes; Devices or Methods Specially Adapted for Bringing Pharmaceutical Products into Particular Physical or Administering Forms; Devices for Administering Food or Medicines Orally; Baby Comforters; Devices for Receiving Spittle A61J 1/00 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 31/58 (20130101) A61K 31/282 (20130101) A61K 31/337 (20130101) A61K 31/357 (20130101) A61K 31/567 (20130101) A61K 31/575 (20130101) Original (OR) Class A61K 31/575 (20130101) A61K 31/4745 (20130101) A61K 31/7068 (20130101) A61K 33/243 (20190101) A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2300/00 (20130101) Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234992 | Gordts et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | Philip Gordts (San Diego, California); Ariane Pessentheiner (San Diego, California); Lars Bode (San Diego, California) |
| ABSTRACT | The disclosure provides for therapies and methods to treat atherosclerosis and/or hyperlipidemia, and complications resulting therefrom, with compositions that comprise therapeutically effective amounts of one or more human milk oligosaccharides. |
| FILED | Thursday, February 28, 2019 |
| APPL NO | 16/289288 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Foods, Foodstuffs, or Non-alcoholic Beverages, Not Covered by Subclasses A23B - A23J; Their Preparation or Treatment, e.g Cooking, Modification of Nutritive Qualities, Physical Treatment; Preservation of Foods or Foodstuffs, in General A23L 33/125 (20160801) Indexing Scheme Relating to Foods, Foodstuffs or Non-alcoholic Beverages A23V 2002/00 (20130101) A23V 2200/326 (20130101) A23V 2200/3262 (20130101) Preparations for Medical, Dental, or Toilet Purposes A61K 9/14 (20130101) A61K 9/20 (20130101) A61K 9/0095 (20130101) A61K 9/4808 (20130101) A61K 31/702 (20130101) A61K 31/7016 (20130101) Original (OR) Class A61K 35/20 (20130101) A61K 45/06 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 3/06 (20180101) A61P 9/10 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234996 | Vaidya et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | The Brigham and Women's Hospital, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | Vishal S. Vaidya (Cambridge, Massachusetts); Casimiro Gerarduzzi (Boston, Massachusetts) |
| ABSTRACT | Described herein are methods for treating fibrosis, e.g., kidney fibrosis, using agents that target Secreted Modular Calcium-binding protein 2 (SMOC2). |
| FILED | Tuesday, February 21, 2017 |
| APPL NO | 16/079002 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/712 (20130101) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 13/12 (20180101) A61P 43/00 (20180101) Peptides C07K 16/18 (20130101) C07K 16/2842 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 2310/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235005 | Halum |
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| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Stacey L. Halum (Indianapolis, Indiana) |
| ABSTRACT | This invention relates to a method for repairing and reconstructing a damaged or non-functional muscle, in particular to a method and a tool kit using in vitro primed motor endplate-expressing muscle progenitor cells (MPCs) to promote innervation of the damaged or non-functional muscle using an agent without any genetic manipulation. This method is particularly useful for repairing or reconstructing damaged or non-functional head and neck muscles, and urinary detrusor bladder muscle. |
| FILED | Friday, April 27, 2018 |
| APPL NO | 15/964784 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/221 (20130101) A61K 35/30 (20130101) A61K 35/34 (20130101) Original (OR) Class A61K 38/1883 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 21/00 (20180101) A61P 25/00 (20180101) A61P 43/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0658 (20130101) C12N 2501/805 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235029 | Cannavo et al. |
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| FUNDED BY |
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| APPLICANT(S) | Temple University-Of The Commonwealth System of Higher Education (Philadelphia, Pennsylvania); Johns Hopkins Technology Ventures (Baltimore, Maryland); Universita di Napoli Federico II (Naples, Italy) |
| ASSIGNEE(S) | Temple University-Of The Commonwealth System of Higher (Philadelphia, Pennsylvania); Education Johns Hopkins Technology Ventures (Baltimore, Maryland); Universita di Napoli Federico II (Naples, Italy) |
| INVENTOR(S) | Alessandro Cannavo (Naples, Italy); Ning Feng (Wexford, Pennsylvania); Giuseppe Rengo (Naples, Italy); Nazareno Paolocci (Baltimore, Maryland); Walter J. Koch (Malvern, Pennsylvania) |
| ABSTRACT | The present invention relates to compositions and methods for the treatment of heart failure. |
| FILED | Friday, March 09, 2018 |
| APPL NO | 15/916494 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/138 (20130101) A61K 31/166 (20130101) A61K 31/353 (20130101) A61K 31/404 (20130101) A61K 38/185 (20130101) Original (OR) Class A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 9/04 (20180101) Peptides C07K 14/71 (20130101) C07K 14/475 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235032 | Wang et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Chensu Wang (Allston, Massachusetts); Karl Dane Wittrup (Boston, Massachusetts); Darrell J. Irvine (Arlington, Massachusetts) |
| ABSTRACT | The present disclosure provides a method of treating cancer with a priming dose of combination immunotherapy comprising IL-2 (e.g., extended-PK IL-2), an immune checkpoint inhibitor, a tumor targeting antibody or integrin-binding polypeptide, and optional cancer vaccine, administered prior to maintenance doses of immune checkpoint inhibitor therapy. The methods of the disclosure can be used to treat a broad range of cancer types. |
| FILED | Friday, November 22, 2019 |
| APPL NO | 16/692892 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/2013 (20130101) Original (OR) Class A61K 39/0011 (20130101) A61K 39/39 (20130101) A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 2039/507 (20130101) A61K 2039/545 (20130101) A61K 2039/55561 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235043 | Lyerly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Herbert K. Lyerly (Durham, North Carolina); Michael A. Morse (Durham, North Carolina); Takuya Osada (Durham, North Carolina); Timothy M. Clay (Waterloo, Belgium); Zachary C. Hartman (Durham, North Carolina) |
| ABSTRACT | Methods of reducing, the likelihood of a cancer or precancer developing resistance to a cancer therapeutic or prevention agent are provided herein. The methods include administering the cancer therapeutic or prevention agent and a vaccine comprising a polynucleotide encoding a polypeptide whose expression or activation is correlated with development of resistance of the cancer or precancer to the cancer therapeutic or prevention agent to a subject. The vaccine may include a polynucleotide encoding a HER3 polypeptide. Methods of using the vaccine including the polynucleotide encoding the HER3 polypeptide to treat a cancer or precancer are also provided. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 15/962824 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 39/001106 (20180801) Original (OR) Class A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/53 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2039/585 (20130101) A61K 2039/5256 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/32 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/77 (20130101) C07K 2317/734 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235045 | Milich et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VLP Biotech, Inc. (San Diego, California) |
| ASSIGNEE(S) | VLP Biotech, Inc. (San Diego, California) |
| INVENTOR(S) | David R. Milich (Escondido, California); David C. Whitacre (San Diego, California) |
| ABSTRACT | The present disclosure relates to rodent hepadnavirus core antigens including one or more B cell and T cell epitopes of a malaria parasite antigen. More specifically, the present disclosure relates to hybrid woodchuck hepadnavirus core antigens that have been modified to diminish the antibody response to the core antigen so as to enhance the antibody response to fragments of malaria antigen(s) included therein. |
| FILED | Tuesday, October 30, 2018 |
| APPL NO | 16/175681 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/015 (20130101) Original (OR) Class A61K 39/29 (20130101) A61K 39/295 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 33/06 (20180101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/701 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235047 | Malley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Children's Medical Center Corporation (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Richard Malley (Beverly, Massachusetts); Yingjie Lu (West Roxbury, Massachusetts); Kristin L. Moffitt (Woburn, Massachusetts) |
| ABSTRACT | The present application is generally directed to methods for identifying immunogens from organisms and pathogens, and in particular for identifying immunogens which when administered as vaccines elicit a cellular and/or humoral immune response. The present application is also directed to pneumococcal T-cell immunogens, and vaccine compositions comprising one or a combination of pneumococcal immunogens and methods for treating or preventing pneumococcal infections using the vaccines thereof. The present invention also encompasses use of the pneumococcal immunogens for diagnostic purposes to identify a subject with a pneumococcal infection. |
| FILED | Tuesday, June 28, 2016 |
| APPL NO | 15/195099 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/092 (20130101) Original (OR) Class A61K 2039/70 (20130101) A61K 2039/55544 (20130101) A61K 2039/55583 (20130101) Peptides C07K 14/3156 (20130101) C07K 2319/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235054 | Dhere et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Serum Institute of India Private Limited (Pune Maharashtra, India); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | Serum Institute of India Private Limited (Pune Maharashtra, India); The United States of America, as Represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Rajeev Mhalasakant Dhere (Pune Maharashtra, India); Sambhaji Shankar Pisal (Pune Maharashtra, India); Jagdish Kamalaji Zade (Pune Maharashtra, India); Rajendra Narayan Sabale (Pune Maharashtra, India); Ravindra Bapurao Kadam (Pune Maharashtra, India); Abhijeet Sanjeev Kamble (Pune Maharashtra, India); Baoming Jiang (Bethesda, Maryland); Roger Glass (Bethesda, Maryland) |
| ABSTRACT | Stable, immunogenic combination vaccine(s) comprising a mixture of antigens for prevention and prophylaxis of infections caused by Rotavirus, Poliomyelitis virus, Haemophilus influenzae, Corynebacterium diphtheriae, Clostridium tetani, Bordetella pertussis and Hepatitis B virus. A multivalent combination vaccine comprises i) significantly dose-reduced Salk-IPV or Sabin-IPV (IPV) antigens prepared by methods of formaldehyde inactivation and alum hydroxide adsorption resulting in maximum D-antigen recovery; ii) Injectable heat inactivated Rotavirus antigen(s) providing broad cross-protective immunity among human rotavirus strains; iii) Hib PRP-carrier protein conjugate having improved stability and immunogenicity; iv) whole cell pertussis antigen with improved immunogenicity and stability; and v) Homogenous fractions of Diphtheria and Tetanus toxoids. Such stable and immunogenic vaccine compositions are made by i) individually adsorbing dose reduced IPV, IRV antigens on alum hydroxide and keeping other antigen(s) unadsorbed or adsorbed on alum phosphate, alum hydroxide, or a combination thereof; and ii) using an order of addition of antigens during blending. |
| FILED | Thursday, August 24, 2017 |
| APPL NO | 16/327513 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/13 (20130101) A61K 39/15 (20130101) Original (OR) Class A61K 39/099 (20130101) A61K 2039/545 (20130101) A61K 2039/5252 (20130101) A61K 2039/55505 (20130101) A61K 2039/55544 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2720/12334 (20130101) C12N 2770/32634 (20130101) Technologies for Adaptation to Climate Change Y02A 50/466 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235055 | Korber et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico); Oxford University Innovation Limited (Oxford, United Kingdom) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico); Isis Innovation Limited (Oxford, United Kingdom) |
| INVENTOR(S) | Bette T. M. Korber (Los Alamos, New Mexico); Tomas Hanke (Oxford, United Kingdom); Andrew McMichael (Oxford, United Kingdom) |
| ABSTRACT | Disclosed herein are mosaic conserved region HIV polypeptides and immunogenic polypeptides including one or more of the mosaic conserved region polypeptides. In some embodiments, the immunogenic polypeptides are included in an immunogenic composition, such as a polyvalent immunogenic composition. Also disclosed herein are methods for treating or inhibiting HIV in a subject including administering one or more of the disclosed immunogenic polypeptides or compositions to a subject having or at risk of HIV infection. In some embodiments, the methods include inducing an immune response in a subject comprising administering to the subject at least one of the disclosed immunogenic polypeptides or a nucleic acid encoding at least one of the immunogenic polypeptides. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/023871 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class Peptides C07K 14/005 (20130101) C07K 14/161 (20130101) C07K 14/162 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16034 (20130101) C12N 2740/16122 (20130101) C12N 2740/16222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235056 | Chen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Xuejun Chen (Clarksburg, Maryland); Jeffrey Boyington (Clarksburg, Maryland); Hongying Duan Holdsworth (McLean, Virginia); Cheng Cheng (Bethesda, Maryland); John R. Mascola (Rockville, Maryland) |
| ABSTRACT | Embodiments of immunogens based on the outer domain of HIV-1 gp120 and methods of their use and production are disclosed. Nucleic acid molecules encoding the immunogens are also provided. In several embodiments, the immunogens can be used to prime an immune response to gp120 in a subject, for example, to treat or prevent an HIV-1 infection in the subject. |
| FILED | Monday, March 26, 2018 |
| APPL NO | 16/496912 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/21 (20130101) Original (OR) Class A61K 2039/5258 (20130101) A61K 2039/55555 (20130101) Peptides C07K 14/005 (20130101) C07K 14/162 (20130101) C07K 2319/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2740/16023 (20130101) C12N 2740/16043 (20130101) C12N 2740/16111 (20130101) C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) C12N 2740/16171 (20130101) Enzymes C12Y 205/01078 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235058 | Yantasee et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PDX Pharmaceuticals, Inc. (Portland, Oregon); Oregon Health and Science University (Portland, Oregon) |
| ASSIGNEE(S) | Oregon Health and Science University (Portland, Oregon); PDX Pharmaceuticals, Inc. (Portland, Oregon) |
| INVENTOR(S) | Wassana Yantasee (Lake Oswego, Oregon); Amanda Lund (Portland, Oregon); Worapol Ngamcherdtrakul (Portland, Oregon); Moataz Reda (Portland, Oregon) |
| ABSTRACT | Disclosed herein are immunotherapeutic constructs comprising a delivery particle, at least one adjuvant, and one or more therapeutic agents/compounds that cause antigen release and/or modulate immunosuppressive tumor microenvironment. These immunotherapeutic constructs create adaptive immunity or anti-cancer immune response(s) that can be used, for instance, to prevent and treat broad types of cancer. Further disclosed are uses of the immunotherapeutic constructs, including to prevent and treat cancer in humans and animals. |
| FILED | Friday, August 21, 2020 |
| APPL NO | 16/999948 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0014 (20130101) A61K 9/0021 (20130101) A61K 9/1676 (20130101) A61K 31/519 (20130101) A61K 31/7105 (20130101) A61K 39/39 (20130101) Original (OR) Class A61K 2039/55561 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) C12N 15/1135 (20130101) C12N 2310/141 (20130101) C12N 2320/31 (20130101) C12N 2320/35 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235066 | Wang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (Ann Arbor, Michigan) |
| INVENTOR(S) | Thomas D. Wang (Ann Arbor, Michigan); Supang Khondee (Phayao, Thailand) |
| ABSTRACT | The present invention relates to micelle drug carriers and methods of using the micelles to deliver drugs to target cells. The micelles are useful, for example, for carrying and targeting drugs for the treatment of cancer to cancer cells. As one example, the disclosure provides pegylated octadecyl lithocholate micelles that are labeled with a peptide ligand for colorectal neo-plasia and that carry the small molecule mTOR inhibitor rapamycin to colorectal cancer cells. |
| FILED | Thursday, December 01, 2016 |
| APPL NO | 15/780277 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/1075 (20130101) A61K 31/436 (20130101) A61K 47/60 (20170801) A61K 47/62 (20170801) A61K 47/554 (20170801) A61K 47/6907 (20170801) Original (OR) Class Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 65/3348 (20130101) C08G 69/10 (20130101) C08G 69/40 (20130101) C08G 81/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235071 | Mao et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland) |
| ASSIGNEE(S) | The Johns Hopkins University (Baltimore, Maryland) |
| INVENTOR(S) | Hai-Quan Mao (Baltimore, Maryland); John Michael Williford (Chicago, Illinois); Maani Archang (Baltimore, Maryland); Il Minn (Ellicott City, Maryland); Yong Ren (Baltimore, Maryland); Jose Luis Santos (Rockville, Maryland); Martin G. Pomper (Baltimore, Maryland) |
| ABSTRACT | Compositions comprising a polymeric micellar nanoparticle composition comprising a block or graft copolymer comprising at least one polycationic polymer and at least one polyethylene glycol (PEG) polymer having an average molecular weight less than 1 kDa, and at least one nucleic acid, wherein the graft or block copolymer and at least one nucleic acid are complexed and condensed into a shaped micellar nanoparticle that is stable in biological media are disclosed. The presently disclosed subject matter also provides a method for preparing the presently disclosed polymeric micellar nanoparticle compositions, a method for targeting at least one metastatic cancer cell in a subject, and a method for treating a disease or condition using the presently disclosed polymeric micellar nanoparticle compositions. |
| FILED | Wednesday, February 07, 2018 |
| APPL NO | 15/890771 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 45/06 (20130101) A61K 47/59 (20170801) A61K 47/60 (20170801) A61K 47/62 (20170801) A61K 47/64 (20170801) A61K 47/6803 (20170801) A61K 47/6935 (20170801) A61K 48/0041 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/88 (20130101) C12N 2810/855 (20130101) C12N 2810/856 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235075 | McMahon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); KENNEDY KRIEGER INSTITUTE, INC. (Baltimore, Maryland); NATIONAL INSTITUTES OF HEALTH (Bethesda, Maryland) |
| ASSIGNEE(S) | THE JOHNS HOPKINS UNIVERSITY (Baltimore, Maryland); KENNEDY KRIEGER INSTITUTE, INC. (Baltimore, Maryland); NATIONAL INSTITUTES OF HEALTH (Bethesda, Maryland) |
| INVENTOR(S) | Michael T. McMahon (Columbia, Maryland); Kannie Wai-Yan Chan (Baltimore, Maryland); Michael Christopher Giano (Frederick, Maryland); Nikita Oskolkov (Reisterstown, Maryland); Joel Patrick Schneider (Frederick, Maryland); Xiaolei Song (Lutherville, Maryland) |
| ABSTRACT | The present invention provides novel hydrogels through peptides, which are designed to self-assemble and produce magnetic resonance (MR) contrast through chemical exchange saturation transfer (CEST). The location and integrity of these gels could consequently be tracked using MR imaging. The self-assembly of the peptides into hydrogels can be brought about by a change in pH, ionic strength, temperature, and concentration of ions. |
| FILED | Monday, April 28, 2014 |
| APPL NO | 14/787039 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 49/14 (20130101) A61K 49/1803 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235076 | Strong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington); The Regents of the Universitv of California (Oakland, California) |
| INVENTOR(S) | Roland K. Strong (Seattle, Washington); Peter Rupert (Seattle, Washington); Rebecca J. Abergel (Berkeley, California); Ilya Captain (Moraga, California); Gauthier J P Deblonde (Berkeley, California) |
| ABSTRACT | Siderocalin-metal chelator combinations that bind metallic radioisotopes used in nuclear medicine with high affinity are described. The high affinity siderocalin-metal chelator combinations include a number of chelator backbone arrangements with functional groups that coordinate with metals. The siderocalin-metal chelator combinations can be used to deliver radionuclides for imaging and therapeutic purposes. |
| FILED | Monday, August 28, 2017 |
| APPL NO | 16/329178 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0478 (20130101) A61K 51/0482 (20130101) Original (OR) Class Separation B01D 15/34 (20130101) B01D 15/3804 (20130101) Peptides C07K 14/47 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 60/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235141 | Lucke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Minnetronix, Inc. (St. Paul, Minnesota) |
| ASSIGNEE(S) | Minnetronix, Inc. (St. Paul, Minnesota) |
| INVENTOR(S) | Lori Lucke (Rosemount, Minnesota); Vlad Bluvshtein (Plymouth, Minnesota); James Kurkowski (Roseville, Minnesota); William Weiss (Mechanicsburg, Pennsylvania) |
| ABSTRACT | Disclosed are systems and methods for use of an inductive link for a communication channel in a transcutaneous energy transfer system. An example system may include a resonant circuit associated with an external primary, a power transistor connected to the resonant circuit and configured to drive the resonant circuit with a first time-varying electrical signal having a frequency, and a power driver connected to the power transistor that is configured to set the frequency of the first time-varying electrical signal to a resonant frequency to enable power transfer from the external primary to an implanted secondary. The example system may further include a communication driver operatively connected to the power transistor and configured to encode the first time-varying electrical signal with a data signal by modulating an attribute of the time-varying electrical signal as electrical power is transferred from the external primary to the implanted secondary. |
| FILED | Monday, September 09, 2019 |
| APPL NO | 16/564210 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 60/148 (20210101) A61M 60/205 (20210101) A61M 60/871 (20210101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3727 (20130101) A61N 1/3787 (20130101) A61N 1/37223 (20130101) Transmission H04B 3/54 (20130101) H04B 3/548 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235152 | Beauchamp et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Baylor College of Medicine (Houston, Texas) |
| ASSIGNEE(S) | Baylor College of Medicine (Houston, Texas) |
| INVENTOR(S) | Michael S. Beauchamp (Houston, Texas); Daniel Yoshor (Houston, Texas); William H. Bosking, III (Austin, Texas) |
| ABSTRACT | One aspect of the invention provides a computer-implemented method of conveying a visual image to a blind subject fitted with a visual prosthesis. The computer-implemented method includes: mapping a representation of a visual image onto a two-dimensional array of points having a resolution greater than or equal to an electrode resolution of the visual prosthesis; identifying one or more continuous paths along the mapped representation; and controlling the visual prosthesis to sequentially actuate electrodes along the one or more paths. Another aspect of the invention provides a system including: a visual prosthesis comprising multiple electrodes; and an imaging processing device in communication with the visual prosthesis. The imaging processing device can be programmed to receive an image and perform any of the methods described herein. |
| FILED | Tuesday, March 05, 2019 |
| APPL NO | 16/970804 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/0543 (20130101) A61N 1/3787 (20130101) A61N 1/36046 (20130101) Original (OR) Class A61N 1/36167 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235177 | Krishnaswamy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DOSEOPTICS LLC (Lebanon, New Hampshire); Venkataramanan Krishnaswamy (Lebanon, New Hampshire); Brian W. Pogue (Hanover, New Hampshire) |
| ASSIGNEE(S) | DoseOptics LLC (Lebanon, New Hampshire) |
| INVENTOR(S) | Venkataramanan Krishnaswamy (Lebanon, New Hampshire); Brian W. Pogue (Hanover, New Hampshire) |
| ABSTRACT | The present invention relates to advanced Cherenkov-based imaging systems, tools, and methods of feedback control, temporal control sequence image capture, and quantification in high resolution dose images. In particular, the present invention provides a system and method for simple, accurate, quick, robust, real-time, water-equivalent characterization of beams from LINACs and other systems producing external-therapy radiation for purposes including optimization, commissioning, routine quality auditing, R&D, and manufacture. The present invention also provides a system and method for rapid and economic characterization of complex radiation treatment plans prior to patient exposure. Further, the present invention also provides a system and method of economically detecting Cherenkov radiation emitted by tissue and other media in real-world clinical settings (e.g., settings illuminated by visible light). |
| FILED | Monday, October 23, 2017 |
| APPL NO | 16/344139 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 5/1067 (20130101) A61N 5/1071 (20130101) A61N 5/1075 (20130101) Original (OR) Class Measurement of Nuclear or X-radiation G01T 1/22 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235972 | Gopalkrishnan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Nikhil Gopalkrishnan (Jamaica Plain, Massachusetts); Thomas E. Schaus (Arlington, Massachusetts); Peng Yin (Brookline, Massachusetts) |
| ABSTRACT | The present disclosure provides, in some aspects, methods and compositions for producing nucleic acid nanostructures having little to no kinetic barriers to self-assembly. |
| FILED | Tuesday, April 11, 2017 |
| APPL NO | 16/092802 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0042 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 1/6811 (20130101) C12Q 2563/155 (20130101) C12Q 2563/155 (20130101) C12Q 2563/157 (20130101) C12Q 2563/157 (20130101) C12Q 2565/133 (20130101) C12Q 2565/133 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236051 | Crew et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Arvinas Operations, Inc. (New Haven, Connecticut) |
| ASSIGNEE(S) | Arvinas Operations, Inc. (New Haven, Connecticut) |
| INVENTOR(S) | Andrew P. Crew (Guilford, Connecticut); Kurt Zimmermann (Durham, Connecticut); Hanqing Dong (Madison, Connecticut); Lawrence B. Snyder (Killingworth, Connecticut) |
| ABSTRACT | The present disclosure relates to bifunctional compounds, which find utility to degrade (and inhibit) Androgen Receptor. In particular, the present disclosure is directed to compounds, which contain on one end a cereblon ligand which binds to the E3 ubiquitin ligase and on the other end a moiety which binds Androgen Receptor, such that Androgen Receptor is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of Androgen Receptor. The present disclosure exhibits a broad range of pharmacological activities associated with compounds according to the present disclosure, consistent with the degradation/inhibition of Androgen Receptor. |
| FILED | Friday, July 24, 2020 |
| APPL NO | 16/938864 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/02 (20130101) A61K 31/166 (20130101) A61K 31/277 (20130101) A61K 31/496 (20130101) A61K 31/497 (20130101) A61K 31/501 (20130101) A61K 31/506 (20130101) A61K 45/06 (20130101) A61K 47/10 (20130101) Heterocyclic Compounds C07D 205/04 (20130101) C07D 209/48 (20130101) C07D 211/76 (20130101) C07D 213/72 (20130101) C07D 221/20 (20130101) C07D 231/12 (20130101) C07D 233/42 (20130101) Original (OR) Class C07D 237/08 (20130101) C07D 239/24 (20130101) C07D 241/04 (20130101) C07D 401/04 (20130101) C07D 401/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236053 | Güner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Emory University (Atlanta, Georgia); Mercer University (Atlanta, Georgia); Howard University (Washington, District of Columbia); Union University (Jackson, Tennessee) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Mercer University (Atlanta, Georgia); Howard University (Washington, District of Columbia); Union University (Jackson, Tennessee) |
| INVENTOR(S) | Osman Güner (Rohnert Park, California); Bernard Lassegue (Decatur, Georgia); Kathy Griendling (Stone Mountain, Georgia); Qian Xu (Changsha, China PRC); David Brown (Durham, North Carolina); J. Phillip Bowen (Atlanta, Georgia); Amol Kulkarni (Silver Spring, Maryland); E. Blake Watkins (Jackson, Tennessee) |
| ABSTRACT | This disclosure relates to compounds and methods of treating or preventing a Nox related disease or condition comprising administering to a subject in need thereof a Nox inhibitor or pharmaceutical compositions comprising a Nox inhibitor disclosed herein, derivatives, or compounds disclosed herein optionally substituted with one or more substitutes including optional salt and prodrug forms. In certain embodiments, this disclosure relates to sulfonylurea compounds and uses reported herein. |
| FILED | Thursday, July 26, 2018 |
| APPL NO | 16/634567 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 213/50 (20130101) C07D 213/65 (20130101) C07D 215/14 (20130101) C07D 239/26 (20130101) Original (OR) Class C07D 307/54 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236074 | Ridky et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Todd Ridky (Bryn Mawr, Pennsylvania); Christopher Natale (Philadelphia, Pennsylvania) |
| ABSTRACT | The present invention includes compounds, compositions comprising the same, and methods using the compounds and/or compositions therein, for modulating skin pigmentation in a mammalian subject. In certain embodiments, the compounds of the invention treat or prevent skin disorders or diseases associated with hyperpigmentation in the subject. In other embodiments, the compounds of the invention act as antagonist to the non-canonical sex steroid hormone receptor GPRE1 and do not bind to a canonical nuclear estrogen receptor (ER). In yet other embodiments, the compounds of the invention comprise acts as agonists to the non-canonical sex steroid hormone receptor PAQR7 and do not bind to a canonical nuclear progesterone receptor (PR). |
| FILED | Wednesday, April 06, 2016 |
| APPL NO | 15/562725 |
| ART UNIT | 1615 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 8/49 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 17/00 (20180101) A61P 17/06 (20180101) A61P 17/14 (20180101) A61P 17/16 (20180101) A61P 17/18 (20180101) Specific Use of Cosmetics or Similar Toilet Preparations A61Q 17/04 (20130101) A61Q 19/02 (20130101) Heterocyclic Compounds C07D 221/16 (20130101) C07D 405/04 (20130101) Original (OR) Class C07D 491/048 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236082 | Bradner et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| ASSIGNEE(S) | Dana-Farber Cancer Institute, Inc. (Boston, Massachusetts) |
| INVENTOR(S) | James E. Bradner (Weston, Massachusetts); Jun Qi (Sharon, Massachusetts); Kwok-kin Wong (Arlington, Massachusetts) |
| ABSTRACT | The present disclosure provides compounds of any one of Formulae (I) and (II). The compounds described herein are inhibitors of histone methyltransferases (e.g., enhancer of zeste homolog 1 (EZH1) and enhancer of zeste homolog 2 (EZH2)) and are useful in treating and/or preventing a broad range of diseases (e.g., proliferative diseases). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein. Further provided in the present disclosure are methods of identifying EZH1 and/or EZH2 inhibitors. |
| FILED | Friday, November 06, 2015 |
| APPL NO | 15/524679 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 471/04 (20130101) Original (OR) Class C07D 519/00 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236097 | Mulcahy et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SITEONE THERAPEUTICS, INC. (Bozeman, Montana); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| ASSIGNEE(S) | SITEONE THERAPEUTICS, INC. (Bozeman, Montana); THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California) |
| INVENTOR(S) | John Mulcahy (Redwood City, California); Hassan Pajouhesh (Mountain View, California); George Miljanich (Redwood City, California); Anton Delwig (Albany, California); Jacob Beckley (Bozeman, Montana); Grant Masaaki Shibuya (South San Francisco, California); Justin Du Bois (Menlo Park, California) |
| ABSTRACT | Provided herein are compounds, pharmaceutical compositions comprising the compounds, methods of preparing the compounds, and methods of using the compounds and compositions in treating conditions associated with voltage-gated sodium channel function where the compounds are 11,13-modified saxitoxins according to Formula (I): where R4, R4a, R7, R7a, and X2 are as described herein. |
| FILED | Thursday, March 29, 2018 |
| APPL NO | 16/499205 |
| ART UNIT | 1626 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 487/14 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236122 | Nitz et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DFH THERAPEUTICS (Gaithersburg, Maryland); The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | DFH THERAPEUTICS (Gaithersburg, Maryland); The United States Of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Theodore J. Nitz (Boyds, Maryland); Carl T. Wild (Gaithersburg, Maryland); David E. Martin (Shawnee, Oklahoma); Eric O. Freed (Frederick, Maryland) |
| ABSTRACT | The present invention concerns novel pharmaceutically active triterpene amine derivatives, pharmaceutical compositions containing the same, their use as medicaments, and the use of the compounds for the manufacture of specific medicaments. The present invention also concerns a method of treatment involving administration of the triterpene amine compounds. Specifically, the compounds are derivatives of betulinic acid having substitutions at one or more of the C-3, C-28 and C-19 positions as further described herein. The novel compounds are useful as antiretroviral agents. In particular, the novel compounds are useful for the treatment of Human Immunodeficiency Virus-1 (HIV-1). |
| FILED | Friday, June 28, 2019 |
| APPL NO | 17/254189 |
| ART UNIT | 1625 — Organic Chemistry |
| CURRENT CPC | Steroids C07J 63/008 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236134 | Kong et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Leopold Kong (Bethesda, Maryland); Ian A. Wilson (La Jolla, California); Natalia De Val (San Diego, California); Andrew B. Ward (San Diego, California); Dennis Burton (La Jolla, California); Linling He (San Diego, California); Jiang Zhu (San Diego, California) |
| ABSTRACT | The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections. |
| FILED | Monday, February 03, 2020 |
| APPL NO | 16/780495 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 47/64 (20170801) A61K 47/6929 (20170801) A61K 2039/645 (20130101) A61K 2039/5258 (20130101) A61K 2039/6031 (20130101) Peptides C07K 14/005 (20130101) C07K 14/162 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236147 | Ingber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| ASSIGNEE(S) | CHILDREN'S MEDICAL CENTER CORPORATION (Boston, Massachusetts) |
| INVENTOR(S) | Donald E. Ingber (Boston, Massachusetts); Mariko Kobayashi (Brookline, Massachusetts) |
| ABSTRACT | TRPV4 activation increases vascular permeability and can be triggered by both chemical and mechanical cues. This activation of TRPV4 can contribute to a number of pathological conditions, e.g., edema, inflammation, hypertension, and/or hyperalgesia. Described herein are methods and compositions relating to inhibition of mechanically-induced TRPV4 activation, e.g., for the treatment of pulmonary edema, edema, inflammation, hypertension, and/or hyperalgesia. |
| FILED | Friday, July 13, 2018 |
| APPL NO | 16/034894 |
| ART UNIT | 1699 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/705 (20130101) C07K 14/70596 (20130101) Original (OR) Class C07K 2319/10 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236148 | Raines et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | WISCONSIN ALUMNI RESEARCH FOUNDATION (Madison, Wisconsin) |
| INVENTOR(S) | Ronald T. Raines (Madison, Wisconsin); Ismet Tanrikulu (Madison, Wisconsin) |
| ABSTRACT | Novel synthetic human scale collagen triple helices assemblies are disclosed. Methods of making self-assembling collagen mimetic peptides that self-assemble into human scale collagen are also disclosed. |
| FILED | Wednesday, June 14, 2017 |
| APPL NO | 15/622966 |
| ART UNIT | 1654 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/78 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236151 | Bu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Wei Bu (Potomac, North Dakota); Masaru Kanekiyo (Chevy Chase, Maryland); Michael Gordon Joyce (Washington, District of Columbia); Jeffrey I. Cohen (Silver Spring, Maryland) |
| ABSTRACT | Antibodies and compositions of matter useful for the detection, diagnosis and treatment of Epstein Barr Virus infection in mammals, and to methods of using those compositions of matter for the same. Also disclosed are proteins, referred to as anti-gp350 antibody probes, and anti-gp350 B-cell probes, that maintain the epitope structure of the CR2-binding region of gp350, but do not bind CR2. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 16/608386 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/05 (20130101) C07K 16/085 (20130101) Original (OR) Class C07K 2317/10 (20130101) C07K 2317/21 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236152 | Kwong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The Trustees of Columbia University in the City of New York (New York, New York) |
| ASSIGNEE(S) | The United States of America, as represented by the Sectetary, Department of Health and Human Services (Bethesda, Maryland); The Trustees of Columbia University in the City of New York (New York, New York) |
| INVENTOR(S) | Peter Kwong (Washington, District of Columbia); Young Do Kwon (Kensington, Maryland); Ivelin Georgiev (Nashville, Tennessee); Gilad Ofek (Gaithersburg, Maryland); Baoshan Zhang (Bethesda, Maryland); Krisha McKee (Columbia, Maryland); John Mascola (Rockville, Maryland); Mark Connors (Bethesda, Maryland); Gwo-Yu Chuang (Rockville, Maryland); Sijy O'Dell (Silver Spring, Maryland); Robert Bailer (Adamstown, Maryland); Mark Louder (Mt. Airy, Maryland); Mangaiarkarasi Asokan (Rockville, Maryland); Richard Schwartz (Bethesda, Maryland); Jonathan Cooper (Arlington, Virginia); Kevin Carlton (Gaithersburg, Maryland); Michael Bender (Washington, District of Columbia); Amarendra Pegu (Potomac, Maryland); Lawrence Shapiro (New York, New York); Tatyana Gindin (New York, New York); Lisa Kueltzo (Gaithersburg, Maryland) |
| ABSTRACT | Neutralizing antibodies that specifically bind to HIV-1 Env and antigen binding fragments of these antibodies are disclosed. Nucleic acids encoding these antibodies, vectors and host cells are also provided. Methods for detecting HIV-1 using these antibodies are disclosed. In addition, the use of these antibodies, antigen binding fragment, nucleic acids and vectors to prevent and/or treat an HIV-1 infection is disclosed. |
| FILED | Thursday, November 03, 2016 |
| APPL NO | 15/772443 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/18 (20180101) Peptides C07K 16/1063 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/33 (20130101) C07K 2317/52 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) C07K 2317/94 (20130101) C07K 2317/565 (20130101) C07K 2317/567 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236153 | Grakoui et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Emory University (Atlanta, Georgia); Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | Emory University (Atlanta, Georgia); Rutgers, the State University of New Jersey (New Brunswick, New Jersey) |
| INVENTOR(S) | Arash Grakoui (Decatur, Georgia); Joseph Marcotrigiano (New Brunswick, New Jersey) |
| ABSTRACT | The present disclosure relates to constructs useful in expressing biotinylated monomers and tetramers produced from these monomers. Specifically, the disclosure provides a construct useful in expressing biotinylated antigen monomers, said construct comprising a viral protein of an ectodomain of Hepatitis C Virus (HCV) envelope glycoprotein E2 or Human Immunodeficiency Virus (HIV) gp140. Further disclosed are methods for production and use of these tetramers in identifying and isolating antigen specific B cells and cloning antibodies thereto. |
| FILED | Friday, September 22, 2017 |
| APPL NO | 16/335891 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 16/109 (20130101) Original (OR) Class C07K 16/1063 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1006 (20130101) C12N 2740/16122 (20130101) C12N 2770/24222 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/686 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236161 | Kochenderfer |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | James N. Kochenderfer (Bethesda, Maryland) |
| ABSTRACT | The invention is directed to a chimeric antigen receptor (CAR) directed against CD19, which comprises an amino acid sequence of any one of SEQ ID NO: 1-SEQ ID NO: 13. The invention also provides T-cells expressing the CAR and methods for destroying malignant B-cells. |
| FILED | Thursday, March 21, 2019 |
| APPL NO | 16/360281 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 35/17 (20130101) Peptides C07K 14/705 (20130101) C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70521 (20130101) C07K 14/70535 (20130101) C07K 14/70578 (20130101) C07K 16/2803 (20130101) Original (OR) Class C07K 16/3061 (20130101) C07K 2317/21 (20130101) C07K 2317/70 (20130101) C07K 2317/622 (20130101) C07K 2319/00 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/33 (20130101) C07K 2319/74 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 5/0636 (20130101) C12N 2510/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236169 | Ruiz-Opazo et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Nelson Ruiz-Opazo (Westwood, Massachusetts); Victoria L. M. Herrera (Westwood, Massachusetts); Francis Joseph Carr (Balmedie, United Kingdom) |
| ABSTRACT | Provided herein are novel compositions comprising anti-DEspR antibodies and fragments thereof derived from 6G8G7 and 7C5B2 anti-DEspR variant antibodies, including fully human, composite engineered human, humanized, monoclonal, and polyclonal anti-DEspR antibodies and fragments thereof, and methods of their use in a variety of therapeutic applications. The compositions comprising the anti-DEspR antibodies and fragments thereof described herein are useful in diagnostic and imaging methods, such as DEspR-targeted molecular imaging of angiogenesis, and for companion diagnostic and/or in vivo non-invasive imaging and/or assessments. |
| FILED | Thursday, January 31, 2019 |
| APPL NO | 16/263202 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 16/2863 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/24 (20130101) C07K 2317/34 (20130101) C07K 2317/52 (20130101) C07K 2317/53 (20130101) C07K 2317/56 (20130101) C07K 2317/76 (20130101) C07K 2317/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236171 | Dimitrov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The U.S.A., as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Dimiter S. Dimitrov (Frederick, Maryland); Weizao Chen (Frederick, Maryland); Terry J. Fry (Aurora, Colorado); Christopher Chien (Falls Church, Virginia); Haiying Qin (Bethesda, Maryland) |
| ABSTRACT | Human monoclonal antibodies that specifically bind Fms-like tyrosine kinase 3 (FLT3) are described. Chimeric antigen receptors (CARs) and other antibody conjugates that include the FLT3-specific monoclonal antibodies are also described. Methods for the diagnosis and treatment of FLT3-associated cancer, such as acute lymphoblastic leukemia (ALL) or acute myeloid leukemia (AML), are further described. |
| FILED | Thursday, December 21, 2017 |
| APPL NO | 16/471485 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 47/6849 (20170801) A61K 47/6929 (20170801) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) A61P 35/02 (20180101) A61P 35/04 (20180101) Peptides C07K 14/7051 (20130101) C07K 14/70517 (20130101) C07K 14/70578 (20130101) C07K 16/468 (20130101) C07K 16/2863 (20130101) Original (OR) Class C07K 2317/21 (20130101) C07K 2317/31 (20130101) C07K 2317/76 (20130101) C07K 2317/565 (20130101) C07K 2317/622 (20130101) C07K 2319/02 (20130101) C07K 2319/03 (20130101) C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/577 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236176 | Reed |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Translational Sciences Inc. (Memphis, Tennessee) |
| ASSIGNEE(S) | Translational Sciences Inc. (Memphis, Tennessee) |
| INVENTOR(S) | Guy L. Reed (Memphis, Tennessee) |
| ABSTRACT | Compositions and methods of using SerpinF2-binding molecules for preventing and/or reducing organ damage, functional disability or mortality in a patient at risk due to the activity of SerpinF2 and/or plasminogen activators on tissue injury. Also provided are compositions and methods of using SerpinF2-binding molecules for inhibiting hemorrhage, edema, and apoptosis. Methods for the preparation of medicaments for such methods of treatment and prevention are provided. |
| FILED | Thursday, March 06, 2014 |
| APPL NO | 14/198804 |
| ART UNIT | 1646 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 2039/505 (20130101) Peptides C07K 16/18 (20130101) C07K 16/38 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236177 | Tsourkas et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Andrew Tsourkas (Bryn Mawr, Pennsylvania); Burcin Altun (Philadelphia, Pennsylvania); Hejia Henry Wang (Philadelphia, Pennsylvania); Feifan Yu (Aberdeen, New Jersey) |
| ABSTRACT | The invention relates to proximity-based sortase-mediated protein purification and ligation. Specifically, the invention relates to techniques that links protein expression/purification with conjugation to therapeutic agents, imaging agents, or linkers. |
| FILED | Thursday, September 14, 2017 |
| APPL NO | 16/333196 |
| ART UNIT | 1644 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Peptides C07K 1/14 (20130101) C07K 7/06 (20130101) C07K 16/40 (20130101) Original (OR) Class C07K 2317/622 (20130101) C07K 2319/20 (20130101) C07K 2319/21 (20130101) C07K 2319/22 (20130101) C07K 2319/70 (20130101) C07K 2319/73 (20130101) C07K 2319/92 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236326 | McKnight |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Oregon (Eugene, Oregon) |
| ASSIGNEE(S) | University of Oregon (Eugene, Oregon) |
| INVENTOR(S) | Jeffrey McKnight (Eugene, Oregon) |
| ABSTRACT | Compositions and methods for assessing protein function are provided. A modified SpyCatcher protein that can include a tag is provided. Modified SpyCatcher proteins linked to a protein of interest, such as a nuclease are also provided. The methods include contacting a SpyCatcher protein and a SpyTagged protein to form a complex that may further include a protein of interest, one or more nucleic acids, and/or a nuclease. The methods can be used to purify a protein of interest or identify or target a protein binding site in a nucleic acid. |
| FILED | Wednesday, June 24, 2020 |
| APPL NO | 16/910507 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 14/315 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/63 (20130101) C12N 15/102 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236327 | Konermann et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | The Broad Institute, Inc. (Cambridge, Massachusetts); Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Silvana Konermann (Cambridge, Massachusetts); David Feldman (Cambridge, Massachusetts); Feng Zhang (Cambridge, Massachusetts); Paul Blainey (Cambridge, Massachusetts) |
| ABSTRACT | The invention provides for use of CRISPR-Cas systems to sort barcoded cells or molecules. Cells or nucleic acid molecules may be sorted from a heterogenous population by targeting a barcode of interest specific for a cell or cell progeny or nucleic acid molecule of interest. |
| FILED | Thursday, December 14, 2017 |
| APPL NO | 15/842315 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 9/22 (20130101) C12N 9/96 (20130101) C12N 15/11 (20130101) C12N 15/907 (20130101) C12N 15/1065 (20130101) Original (OR) Class C12N 15/1065 (20130101) C12N 15/1082 (20130101) C12N 2310/20 (20170501) C12N 2310/531 (20130101) C12N 2740/15043 (20130101) C12N 2750/14143 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 2563/179 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236330 | Rigo et al. |
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| FUNDED BY |
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| APPLICANT(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California); Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
| ASSIGNEE(S) | Ionis Pharmaceuticals, Inc. (Carlsbad, California); Cold Spring Harbor Laboratory (Cold Spring Harbor, New York) |
| INVENTOR(S) | Frank Rigo (Carlsbad, California); C. Frank Bennett (Carlsbad, California); Adrian R. Krainer (Huntington Station, New York); Zhenxun Wang (Singapore, Singapore) |
| ABSTRACT | The present invention provides compounds comprising oligonucleotides complementary to a pyruvate kinase M transcript. Certain such compounds are useful for hybridizing to a pyruvate kinase M transcript, including but not limited to a pyruvate kinase M transcript in a cell. In certain embodiments, such hybridization results in modulation of splicing of the pyruvate kinase M transcript. In certain embodiments, such compounds are used to treat one or more symptoms associated with cancer. |
| FILED | Tuesday, October 02, 2018 |
| APPL NO | 16/149941 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 15/1137 (20130101) C12N 2310/11 (20130101) C12N 2310/14 (20130101) Enzymes C12Y 207/0104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236337 | Ju et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Research Foundation for The State University of New York (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for The State University of New York (Albany, New York) |
| INVENTOR(S) | Jingfang Ju (East Setauket, New York); Andrew Fesler (Sound Beach, New York); Younghwa Song (Port Jefferson Station, New York); Jun Chung (Setauket, New York) |
| ABSTRACT | The present disclosure provides nucleic acid compositions that incorporate one or more halouracil molecules. More specifically, the present disclosure reveals that the replacement of uracil nucleotides within a microRNA nucleotide sequence with a 5-halouracil increases the ability of the micro-RNA to inhibit cancer progression and tumorigenesis. As such, the present disclosure provides various nucleic acid (e.g., microRNA) compositions having 5-halouracil molecules incorporated in their nucleic acid sequences and methods for using the same. The present disclosure further provides pharmaceutical compositions comprising the modified nucleic acid compositions, and methods for treating cancers using the same. |
| FILED | Friday, June 26, 2020 |
| APPL NO | 16/912932 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/113 (20130101) Original (OR) Class C12N 2310/141 (20130101) C12N 2310/335 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236340 | Wyss-Coray et al. |
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| FUNDED BY |
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| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Anton Wyss-Coray (Palo Alto, California); Thomas A. Rando (Stanford, California); Markus Britschgi (Allscwil, Switzerland); Kaspar Rufibach (Basel, Switzerland); Saul A. Villeda (Lancaster, California) |
| ABSTRACT | Methods of treating an adult mammal for an aging-associated impairment are provided. Aspects of the methods include modulating CCR3, e.g., by modulating eotaxin-1/CCR3 interaction, in the mammal in a manner sufficient to treat the mammal for the aging-associated impairment. A variety of aging-associated impairments may be treated by practice of the methods, which impairments include cognitive impairments. |
| FILED | Tuesday, April 07, 2020 |
| APPL NO | 16/842054 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/7088 (20130101) A61K 38/19 (20130101) A61K 38/45 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/24 (20130101) C07K 16/28 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2799/06 (20130101) C12N 2799/022 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 207/10001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236345 | Coller et al. |
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| FUNDED BY |
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| APPLICANT(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| ASSIGNEE(S) | CASE WESTERN RESERVE UNIVERSITY (Cleveland, Ohio) |
| INVENTOR(S) | Jeffery M. Coller (Novelty, Ohio); Kristian E. Baker (Novelty, Ohio) |
| ABSTRACT | A synthetic nucleic acid which encodes a protein wherein at least one optimal or non-optimal codon in a wild type nucleic acid encoding the protein has been replaced respectively with one or more non-optimal codons or optimal codons encoding the same amino acid. |
| FILED | Wednesday, March 09, 2016 |
| APPL NO | 15/557412 |
| ART UNIT | 1636 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/67 (20130101) C12N 15/68 (20130101) Original (OR) Class C12N 15/81 (20130101) C12N 15/85 (20130101) C12N 2800/22 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 21/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236359 | Mali et al. |
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| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Prashant G. Mali (Somerville, Massachusetts); George M. Church (Brookline, Massachusetts); Luhan Yang (Somerville, Massachusetts) |
| ABSTRACT | A method of altering a eukaryotic cell is provided including transfecting the eukaryotic cell with a nucleic acid encoding RNA complementary to genomic DNA of the eukaryotic cell, transfecting the eukaryotic cell with a nucleic acid encoding an enzyme that interacts with the RNA and cleaves the genomic DNA in a site specific manner, wherein the cell expresses the RNA and the enzyme, the RNA binds to complementary genomic DNA and the enzyme cleaves the genomic DNA in a site specific manner. |
| FILED | Friday, February 12, 2016 |
| APPL NO | 15/042573 |
| ART UNIT | 1658 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/22 (20130101) C12N 15/01 (20130101) C12N 15/10 (20130101) C12N 15/63 (20130101) C12N 15/81 (20130101) C12N 15/85 (20130101) Original (OR) Class C12N 15/87 (20130101) C12N 15/90 (20130101) C12N 15/102 (20130101) C12N 15/907 (20130101) C12N 15/1024 (20130101) C12N 15/8201 (20130101) C12N 2310/20 (20170501) C12N 2800/80 (20130101) C12N 2810/55 (20130101) Enzymes C12Y 301/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236360 | Schmidt |
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| FUNDED BY |
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| APPLICANT(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| ASSIGNEE(S) | Regents of the University of Minnesota (Minneapolis, Minnesota) |
| INVENTOR(S) | Daniel Schmidt (Minneapolis, Minnesota) |
| ABSTRACT | Methods to prepare recombinant adeno-associated virus (AAV) capsids with altered tropism and compositions having AAVs with altered tropism are provided. |
| FILED | Friday, December 08, 2017 |
| APPL NO | 15/836345 |
| ART UNIT | 1633 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/0008 (20130101) Peptides C07K 14/00 (20130101) C07K 14/005 (20130101) C07K 14/46 (20130101) C07K 14/43518 (20130101) C07K 2319/02 (20130101) C07K 2319/20 (20130101) C07K 2319/21 (20130101) C07K 2319/42 (20130101) C07K 2319/55 (20130101) C07K 2319/60 (20130101) C07K 2319/70 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/86 (20130101) Original (OR) Class C12N 15/1082 (20130101) C12N 15/1093 (20130101) C12N 2750/14122 (20130101) C12N 2750/14145 (20130101) C12N 2750/14151 (20130101) C12N 2750/14171 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236383 | Berman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Bio-Rad Laboratories, Inc. (Hercules, California); J. David Gladstone Institutes (San Francisco, California) |
| ASSIGNEE(S) | Bio-Rad Laboratories, Inc. (Hercules, California); J. David Gladstone Institute (San Francisco, California) |
| INVENTOR(S) | Jennifer Berman (San Carlos, California); Samantha Cooper (Berkeley, California); George Karlin-Neumann (Palo Alto, California); Yuichiro Miyaoka (San Francisco, California); Bruce Conklin (San Francisco, California); Josh Shinoff (Emeryville, California) |
| ABSTRACT | Methods, compositions, and kits are provided for quantification of genome editing. |
| FILED | Wednesday, March 13, 2019 |
| APPL NO | 16/352600 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/63 (20130101) C12N 15/102 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) C12Q 1/6809 (20130101) C12Q 1/6827 (20130101) Original (OR) Class C12Q 2537/143 (20130101) C12Q 2563/159 (20130101) C12Q 2565/101 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236389 | Feldman et al. |
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| FUNDED BY |
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| APPLICANT(S) | Temple University of the Commonwealth System of Higher Education (Philadelphia, Pennsylvania) |
| ASSIGNEE(S) | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (Philadelphia, Pennsylvania) |
| INVENTOR(S) | Arthur M. Feldman (Wynnewood, Pennsylvania); Douglas G. Tilley (Bryn Mawr, Pennsylvania); Weizhong Zhu (Cockeysville, Maryland); Kamel Khalili (Bala Cynwyd, Pennsylvania); Walter J. Koch (Broomall, Pennsylvania) |
| ABSTRACT | Compositions are directed to BCL2-associated athanogene 3 (BAG3) molecules and agents which modulate expression of BAG3 molecules. Pharmaceutical composition for administration to patients, for example, patients with heart failure, comprise one or more BAG3 molecules or agents which modulate expression of BAG3. Methods of treatment and identifying candidate therapeutic agents are also provided. |
| FILED | Friday, January 30, 2015 |
| APPL NO | 15/115807 |
| ART UNIT | 1635 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 48/00 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/6887 (20130101) G01N 33/6893 (20130101) G01N 2500/04 (20130101) G01N 2500/10 (20130101) G01N 2800/50 (20130101) G01N 2800/325 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236393 | Rotter et al. |
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| FUNDED BY |
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| APPLICANT(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| ASSIGNEE(S) | CEDARS-SINAI MEDICAL CENTER (Los Angeles, California) |
| INVENTOR(S) | Jerome I. Rotter (Los Angeles, California); Marla Dubinsky (Los Angeles, California); Stephan R. Targan (Santa Monica, California); Kent D. Taylor (Ventura, California) |
| ABSTRACT | The present invention relates to methods of prognosing responsiveness to anti-TNFα therapy by determining the presence or absence of risk factors in the individual. In one embodiment, the risk factors are genetic markers, serological markers and/or clinical phenotypes associated with non-responsiveness to treatment with anti-TNFα therapy in an individual diagnosed with IBD. |
| FILED | Monday, July 02, 2018 |
| APPL NO | 16/025769 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) Original (OR) Class C12Q 2600/106 (20130101) C12Q 2600/156 (20130101) C12Q 2600/172 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236395 | Petrovics et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Gyorgy Petrovics (Bethesda, Maryland); Shiv Srivastava (Potomac, Maryland) |
| ABSTRACT | The present invention relates to oncogenes or tumor suppressor genes, as well as other genes, involved in prostate cancer and their expression products, as well as derivatives and analogs thereof. Provided are therapeutic compositions and methods of detecting and treating cancer, including prostate and other related cancers. Also provided are methods of diagnosing and/or prognosing prostate cancer by determining the expression level of at least one prostate cancer-cell-specific gene, including, for example, the ERG gene or the LTF gene alone, or in combination with at least one of the AMACR gene and the DD3 gene. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/977443 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 16/30 (20130101) C07K 16/32 (20130101) C07K 2317/33 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236398 | Glazko et al. |
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| FUNDED BY |
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| APPLICANT(S) | BioVentures, LLC (Little Rock, Arkansas); The United States As Represented By The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | BioVentures, LLC (Little Rock, Arkansas); The United States As Represented By The Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Galina Glazko (Little Rock, Arkansas); Curt H. Hagedorn (Little Rock, Arkansas); Yasir Rahmatallah (Little Rock, Arkansas) |
| ABSTRACT | The disclosure provides a method to detect sessile serrated adenomas/polyps (SSA/Ps) and to differentiate SSA/Ps from hyperplastic polyps (HPs). The method uses a molecular signature that is platform-independent and could be used with multiple platforms such as microarray, RNA-seq or real-time quantitative platforms. |
| FILED | Thursday, March 01, 2018 |
| APPL NO | 16/489604 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/7028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236402 | Schaffer et al. |
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| FUNDED BY |
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| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | The Regents of the University of California (Oakland, California) |
| INVENTOR(S) | David V. Schaffer (Danville, California); Ryan R. Klimczak (San Francisco, California); James T. Koerber (San Francisco, California); John G. Flannery (Berkeley, California); Deniz Dalkara Mourot (Berkeley, California); Meike Visel (El Cerrito, California); Leah C. T. Byrne (Berkeley, California) |
| ABSTRACT | The present disclosure provides adeno-associated virus (AAV) virions with altered capsid protein, where the AAV virions exhibit greater infectivity of retinal cells, when administered via intravitreal injection, compared to wild-type AAV. The present disclosure further provides methods of delivering a gene product to a retinal cell in an individual, and methods of treating ocular disease. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/230080 |
| ART UNIT | 1632 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 9/0048 (20130101) A61K 38/1709 (20130101) A61K 48/0008 (20130101) A61K 48/0025 (20130101) A61K 48/0075 (20130101) Peptides C07K 14/005 (20130101) C07K 2319/33 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 15/86 (20130101) C12N 15/113 (20130101) C12N 15/115 (20130101) C12N 2310/14 (20130101) C12N 2310/16 (20130101) C12N 2320/32 (20130101) C12N 2750/14021 (20130101) C12N 2750/14121 (20130101) C12N 2750/14122 (20130101) C12N 2750/14142 (20130101) C12N 2750/14143 (20130101) C12N 2750/14145 (20130101) C12N 2750/14152 (20130101) C12N 2810/40 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/70 (20130101) C12Q 1/701 (20130101) Original (OR) Class C12Q 2600/16 (20130101) C12Q 2600/158 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5008 (20130101) G01N 33/5058 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237111 | Cheng et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Boston University (Boston, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF BOSTON UNIVERSITY (Boston, Massachusetts) |
| INVENTOR(S) | Ji-Xin Cheng (Newton, Massachusetts); Haonan Lin (Allston, Massachusetts) |
| ABSTRACT | Systems and methods implement of high-speed delay scanning for spectroscopic SRS imaging characterized by scanning a first pulsed beam across a stepwise reflective surface (such as a stepwise mirror or a reflective blazed grating) in a Littrow configuration to generate near continuous temporal delays relative to a second pulsed beam. Systems and methods also implement deep learning techniques for image restoration of spectroscopic SRS images using a trained encoder-decoder convolution neural network (CNN) which in some embodiments may be designed as a spatial-spectral residual net (SS-ResNet) characterized by two parallel filters including a first convolution filter on the spatial domain and a second convolution filter on the spectral domain. |
| FILED | Friday, January 29, 2021 |
| APPL NO | 17/162455 |
| ART UNIT | 2664 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0075 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/65 (20130101) Original (OR) Class G01N 2021/655 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Image Data Processing or Generation, in General G06T 5/001 (20130101) G06T 2207/20081 (20130101) G06T 2207/20084 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237131 | Molho et al. |
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| FUNDED BY |
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| APPLICANT(S) | ProteinSimple (Santa Clara, California) |
| ASSIGNEE(S) | ProteinSimple (Santa Clara, California) |
| INVENTOR(S) | Joshua I. Molho (Oakland, California); Kelly Gardner (Berkeley, California); Danh C. Tran (Hayward, California); Eric Jabart (Berkeley, California); David Nilson (Walnut Creek, California); Yuri Kouchnir (Sunnyvale, California); Michael Huston (San Jose, California); Colin B. Kennedy (Greenbrae, California); David John Roach (Los Gatos, California) |
| ABSTRACT | A system for assaying a biological sample for a presence of a target analyte includes an assaying device and a computer controller. The assaying device includes a housing, a receptacle disposed in the housing, and a source of activation energy. The receptacle is configured to accept an electrophoresis cell. The electrophoresis cell has a recess area configured to accept a chip configured to accept the biological sample. The chip includes a polymeric separation medium with activatable functional groups that covalently bond to the target analyte when activated. The source of activation energy is configured to supply activation energy to activate the activatable functional groups. The computer controller is operably coupled to the source of activation energy and is configured to activate the source of activation energy to direct an application of activation energy to the polymeric separation medium to activate the activatable functional groups. |
| FILED | Friday, May 20, 2016 |
| APPL NO | 15/160636 |
| ART UNIT | 1795 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/44704 (20130101) G01N 27/44726 (20130101) G01N 27/44739 (20130101) G01N 27/44752 (20130101) G01N 27/44756 (20130101) G01N 27/44782 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237169 | Hewitt et al. |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America, as represented by the Secretary, Dept. of Health and Human Services (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland) |
| INVENTOR(S) | Stephen M. Hewitt (Potomac, Maryland); Joon-Yong Chung (Rockville, Maryland) |
| ABSTRACT | Compositions, methods and kits are described for identifying biomolecules (e.g., proteins and nucleic acids) expressed in a biological sample that are associated with the presence, development, or progression of a disease (such as cancer), or more generally determination of the etiology or risk factors associated with a disease. Sample types analyzed by the disclosed methods include but are not limited to archival tissue blocks that have been preserved in a fixative, tissue biopsy samples, tissue microarrays, and so forth. The methods disclosed herein correlate expression profiles of biomolecules with various disease types, and allow for the determination of relative survival rates; in some embodiments, the methods permit determination of survival rates for a subject with cancer. In other embodiments, the disclosure relates to methods for evaluating therapeutic regimes for the treatment, such as treatment of cancer. |
| FILED | Wednesday, December 12, 2018 |
| APPL NO | 16/217540 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/582 (20130101) G01N 33/57484 (20130101) Original (OR) Class G01N 2800/60 (20130101) Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 25/10 (20190201) G16B 99/00 (20190201) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 50/20 (20180101) Information and Communication Technology [ICT] Specially Adapted for Specific Application Fields, Not Otherwise Provided for G16Z 99/00 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237233 | Yan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | VANDERBILT UNIVERSITY (Nashville, Tennessee) |
| ASSIGNEE(S) | Vanderbilt University (Nashville, Tennessee) |
| INVENTOR(S) | Xinqiang Yan (Nashville, Tennessee); John C. Gore (Nashville, Tennessee); William A. Grissom (Nashville, Tennessee) |
| ABSTRACT | A self-decoupled RF coil and method for adjusting the same is disclosed. The RF coil is an array of elements including at least one loop. Electromagnetic coupling between elements in the array causes an induced current in the at least one loop. The induced current has two modes. A reactance inserted in the at least one loop balances the two modes. The balanced current modes cancel. This cancelation results in self-decoupling of at the least one loop from the other elements in the RF coil array. |
| FILED | Wednesday, March 21, 2018 |
| APPL NO | 16/495135 |
| ART UNIT | 2866 — Printing/Measuring and Testing |
| CURRENT CPC | Measuring Electric Variables; Measuring Magnetic Variables G01R 33/365 (20130101) Original (OR) Class G01R 33/3415 (20130101) G01R 33/3635 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238956 | Gilbert et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida) |
| INVENTOR(S) | David M. Gilbert (Tallahassee, Florida); Juan Carlos Rivera-Mulia (Tallahassee, Florida) |
| ABSTRACT | Methods for identifying and classifying differences between biological samples are based on replication timing (RT) data. By comparing RT data for a test sample(s) to RT data for already characterized samples, one can identify differences and profile any new cell type or disease. These new methods allow for the detection of all the changes between distinct samples, many of which would escape detection by previous methods that discard any features showing any intra-sample variation. |
| FILED | Tuesday, June 06, 2017 |
| APPL NO | 15/615069 |
| ART UNIT | 1631 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Bioinformatics, i.e Information and Communication Technology [ICT] Specially Adapted for Genetic or Protein-related Data Processing in Computational Molecular Biology G16B 20/00 (20190201) G16B 20/20 (20190201) Original (OR) Class G16B 25/00 (20190201) G16B 25/10 (20190201) G16B 30/00 (20190201) G16B 40/00 (20190201) G16B 40/30 (20190201) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238975 | El-Baz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| ASSIGNEE(S) | University of Louisville Research Foundation, Inc. (Louisville, Kentucky) |
| INVENTOR(S) | Ayman S. El-Baz (Louisville, Kentucky); Amy Dwyer (Goshen, Kentucky); Ahmed Soliman (Louisville, Kentucky); Mohamed Shehata (Louisville, Kentucky); Hisham Abdeltawab (Louisville, Kentucky); Fahmi Khalifa (Louisville, Kentucky) |
| ABSTRACT | A computer aided diagnostic system and automated method to classify a kidney utilizes medical image data and clinical biomarkers in evaluation of kidney function pre- and post-transplantation. The system receives image data from a medical scan that includes image data of a kidney, then segments kidney image data from other image data of the medical scan. The kidney is then classified by analyzing at least one feature determined from the kidney image data and the at least one clinical biomarker. |
| FILED | Friday, February 22, 2019 |
| APPL NO | 16/282753 |
| ART UNIT | 2661 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/201 (20130101) A61B 5/0261 (20130101) A61B 5/0295 (20130101) A61B 5/4848 (20130101) A61B 5/7264 (20130101) A61B 5/14546 (20130101) A61B 2505/05 (20130101) A61B 2576/02 (20130101) Image Data Processing or Generation, in General G06T 7/0012 (20130101) G06T 7/12 (20170101) G06T 7/33 (20170101) G06T 7/143 (20170101) G06T 2207/10088 (20130101) G06T 2207/10096 (20130101) G06T 2207/20081 (20130101) G06T 2207/30084 (20130101) Healthcare Informatics, i.e Information and Communication Technology [ICT] Specially Adapted for the Handling or Processing of Medical or Healthcare Data G16H 30/20 (20180101) G16H 30/40 (20180101) Original (OR) Class G16H 50/20 (20180101) G16H 50/30 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239065 | Eberlin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| ASSIGNEE(S) | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas) |
| INVENTOR(S) | Livia Schiavinato Eberlin (Austin, Texas); Thomas Milner (Austin, Texas); Jialing Zhang (Austin, Texas); John Lin (Austin, Texas); John Rector (Austin, Texas); Nitesh Katta (Austin, Texas); Aydin Zahedivash (Austin, Texas) |
| ABSTRACT | Method and devices are provided for assessing tissue samples from a plurality of tissue sites in a subject using molecular analysis. In certain aspects, devices of the embodiments allow for the collection of liquid tissue samples and delivery of the samples for mass spectrometry analysis. |
| FILED | Monday, November 30, 2020 |
| APPL NO | 17/106445 |
| ART UNIT | 2881 — Optics |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 10/0045 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/0293 (20130101) B01L 3/502 (20130101) B01L 2200/0605 (20130101) B01L 2400/0655 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/02 (20130101) G01N 30/72 (20130101) G01N 33/487 (20130101) G01N 33/574 (20130101) G01N 33/6848 (20130101) G01N 2001/028 (20130101) G01N 2001/4061 (20130101) G01N 2560/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 49/04 (20130101) H01J 49/0031 (20130101) H01J 49/0431 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Defense (DOD)
| US 11234678 | Huang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Lianjie Huang (Los Alamos, New Mexico); Zhigang Zhang (Los Alamos, New Mexico) |
| ABSTRACT | Ultrasound tomography imaging methods for imaging a tissue medium with one or more ultrasound transducer arrays comprising a plurality of transducers, wherein said transducers comprise source transducers, receiving transducers. The methods include assigning a phase value or time delay to source transducers, exciting the transducers and calculating a search direction based on data relating to the excited transducers. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/045279 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0073 (20130101) A61B 5/7275 (20130101) A61B 8/13 (20130101) A61B 8/14 (20130101) A61B 8/15 (20130101) A61B 8/085 (20130101) A61B 8/145 (20130101) A61B 8/406 (20130101) A61B 8/483 (20130101) A61B 8/0825 (20130101) A61B 8/4477 (20130101) A61B 8/4488 (20130101) A61B 8/4494 (20130101) A61B 8/5207 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/8915 (20130101) G01S 15/8929 (20130101) G01S 15/8997 (20130101) Image Data Processing or Generation, in General G06T 5/001 (20130101) G06T 11/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11234998 | McCarthy et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Tricol Biomedical, Inc. (Portland, Oregon) |
| ASSIGNEE(S) | Tricol Biomedical, Inc. (Portland, Oregon) |
| INVENTOR(S) | Simon McCarthy (Portland, Oregon); Barbara McGrath (Portland, Oregon); Sam Kuhn (Portland, Oregon); Jess Kimball (Portland, Oregon); Michael Stolten (New Orleans, Louisiana); Amanda Bennett (New Orleans, Louisiana) |
| ABSTRACT | The present invention comprises chitosan materials and methods of using carbonic acid for aqueous solubilization of neutralized or pre-treated chitosan gels and provides, among other things, substantially acid salt free composition native final forms without requiring subsequent acid salt elution. The invention includes chitosan-based solid and semi-solid material forms, optionally reinforced with chitosan fibers, such as powders, fibers, films, matrices, sponges, implants, scaffolds, fillers, and hydrogels. Native final forms are produced from chitosan powder solubilized in an aqueous acidic solution, processed to form a high pH hydrated chitosan gel precipitate material that is then neutralized by water washing and re-solubilized substantially to chitosan solution using carbonic acid. Chitosan materials can be mixed in solution with one or more of other hydrophilic polymers to create compositional heterogeneity and pharmaceutical agents to achieve controlled release of the agent(s) from the final forms at the site of application. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 16/821459 |
| ART UNIT | 1623 — Organic Chemistry |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/19 (20130101) A61K 9/70 (20130101) A61K 9/1652 (20130101) A61K 9/1694 (20130101) A61K 31/722 (20130101) Original (OR) Class A61K 47/12 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235043 | Lyerly et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Duke University (Durham, North Carolina) |
| ASSIGNEE(S) | Duke University (Durham, North Carolina) |
| INVENTOR(S) | Herbert K. Lyerly (Durham, North Carolina); Michael A. Morse (Durham, North Carolina); Takuya Osada (Durham, North Carolina); Timothy M. Clay (Waterloo, Belgium); Zachary C. Hartman (Durham, North Carolina) |
| ABSTRACT | Methods of reducing, the likelihood of a cancer or precancer developing resistance to a cancer therapeutic or prevention agent are provided herein. The methods include administering the cancer therapeutic or prevention agent and a vaccine comprising a polynucleotide encoding a polypeptide whose expression or activation is correlated with development of resistance of the cancer or precancer to the cancer therapeutic or prevention agent to a subject. The vaccine may include a polynucleotide encoding a HER3 polypeptide. Methods of using the vaccine including the polynucleotide encoding the HER3 polypeptide to treat a cancer or precancer are also provided. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 15/962824 |
| ART UNIT | 1642 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/517 (20130101) A61K 31/517 (20130101) A61K 39/001106 (20180801) Original (OR) Class A61K 39/3955 (20130101) A61K 45/06 (20130101) A61K 2039/53 (20130101) A61K 2039/505 (20130101) A61K 2039/507 (20130101) A61K 2039/585 (20130101) A61K 2039/5256 (20130101) A61K 2300/00 (20130101) Peptides C07K 16/32 (20130101) C07K 2317/73 (20130101) C07K 2317/76 (20130101) C07K 2317/77 (20130101) C07K 2317/734 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235046 | Brett et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION, ON BEHALF OF THE UNIVERSITY OF NEVADA (Reno, Nevada) |
| ASSIGNEE(S) | Nevada Research and Innovation Corporation (Reno, Nevada) |
| INVENTOR(S) | Paul J. Brett (Reno, Nevada); Mary N. Burtnick (Reno, Nevada) |
| ABSTRACT | Disclosed are capsular polysaccharide (CPS)-protein immunogenic conjugates useful for providing protection against any condition or disease associated with Burkholderia pseudomallei or Burkholderia mallei, such as melioidosis or glanders, respectively. For example, a disclosed CPS-protein immunogenic conjugate includes purified 6-deoxyheptan capsular polysaccharide (CPS) from B. pseudomallei chemically activated and covalently linked to recombinant CRM 197 diphtheria toxin mutant (CRM197) to produce CPS-CRM197. Methods of inducing an immune response are disclosed. The methods include the use of a CPS-protein immunogenic conjugate, alone or in conjunction with other agents, such as Hcp1 and TssM, to prevent infection with B. pseudomallei or B. mallei. Also disclosed are methods for treating a subject having melioidosis or glanders. |
| FILED | Friday, November 02, 2018 |
| APPL NO | 16/760418 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/02 (20130101) Original (OR) Class A61K 47/646 (20170801) A61K 47/6415 (20170801) A61K 2039/6037 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235183 | Dashevsky et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Orbital Research Inc. (Cleveland, Ohio) |
| ASSIGNEE(S) | Orbital Research Inc. (Cleveland, Ohio) |
| INVENTOR(S) | David Dashevsky (Cupertino, California); Matthew Birch (Madison, Alabama); Aaron T. Rood (Rocky River, Ohio); Frederick J. Lisy (Euclid, Ohio) |
| ABSTRACT | A wearable device for comprehensive bio-monitoring of physiologic metrics to determine metabolic, pulmonary and cardiac function and oxygen saturation measurements from breathing mask apparatuses. The device non-invasively monitors the physiologic profile of the subject, and is capable of detecting physiologic changes, predicting onset of symptoms, and alerting the wearer or another person or system. In some embodiments, the device comprises both a wearable sensor suite and a portable gas composition and flow analysis system. In preferred embodiments, it comprises a miniaturized non-invasive sensor suite for detecting physiologic changes to detect dangerous breathing or other health conditions. The acquired physiologic profile is used to generate alarms or warnings based on detectable physiological changes, to adjust gas delivery to the subject, alter mission profiles, or to transfer control of the craft or other duties away from a debilitated subject. The device is compact, portable, vehicle independent and non-encumbering to the subject. |
| FILED | Tuesday, April 09, 2019 |
| APPL NO | 16/379173 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/486 (20130101) A61B 5/0833 (20130101) A61B 5/0836 (20130101) A61B 5/6803 (20130101) A61B 5/7225 (20130101) A61B 5/7275 (20130101) A61B 5/7278 (20130101) Devices, Apparatus or Methods for Life-saving A62B 7/14 (20130101) A62B 9/006 (20130101) Original (OR) Class A62B 18/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235291 | Medina et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | United States of America as Represented by The Secretary of The Army (Alexandria, Virginia) |
| ASSIGNEE(S) | UNITED STATES of AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (Alexandria, Virginia) |
| INVENTOR(S) | Victor F Medina (Clinton, Mississippi); Christopher S Griggs (Vicksburg, Mississippi); Jose Mattei-Sosa (Vicksburg, Mississippi); Brooke Petery (Schwenksville, Pennsylvania); Luke Gurtowski (Vicksburg, Mississippi) |
| ABSTRACT | A composition of five parts by mass of chitosan and one part graphene oxide is suspended in water. The composition may be used to form filtration layers of any size or shape and may be reinforced by additional layers. The composition may be used to construct a large filtration apparatus of any size or shape and may be used to form highly resilient, antimicrobial structures and surfaces for a variety of applications. |
| FILED | Monday, March 23, 2020 |
| APPL NO | 16/826296 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 63/10 (20130101) B01D 67/0079 (20130101) B01D 69/02 (20130101) B01D 69/10 (20130101) B01D 69/12 (20130101) B01D 69/148 (20130101) Original (OR) Class B01D 71/08 (20130101) B01D 71/021 (20130101) B01D 71/024 (20130101) B01D 71/74 (20130101) B01D 2319/06 (20130101) B01D 2323/12 (20130101) B01D 2323/30 (20130101) B01D 2325/04 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/44 (20130101) C02F 1/441 (20130101) C02F 2303/04 (20130101) C02F 2303/20 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235894 | Nevarez et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOEING COMPANY (Chicago, Illinois) |
| ASSIGNEE(S) | THE BOEING COMPANY (Chicago, Illinois) |
| INVENTOR(S) | Moises Nevarez (Long Beach, California); Robert J. Perez (Huntington Beach, California); Stephanie C. Klimczak (St. Louis, Missouri); Jonathan D. Embler (Tustin, California) |
| ABSTRACT | A method for building an aerodynamic structure, an aerodynamic structure, and a vehicle that includes the aerodynamic structure are provided. The method includes providing a structure with at least one substantially-flat exterior surface. The method also includes attaching blocks of rigid fibrous insulation to the at least one substantially-flat outer surface of the structure. Outward-facing surfaces of the blocks of rigid fibrous insulation extend past a target outer mold line of a final aerodynamic shape. The method also includes machining the outward-facing surfaces of the attached blocks to the outer mold line. |
| FILED | Monday, December 16, 2019 |
| APPL NO | 16/715346 |
| ART UNIT | 3642 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Aeroplanes; Helicopters B64C 1/12 (20130101) B64C 1/40 (20130101) B64C 3/26 (20130101) Cosmonautics; Vehicles or Equipment Therefor B64G 1/14 (20130101) B64G 1/58 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235972 | Gopalkrishnan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Nikhil Gopalkrishnan (Jamaica Plain, Massachusetts); Thomas E. Schaus (Arlington, Massachusetts); Peng Yin (Brookline, Massachusetts) |
| ABSTRACT | The present disclosure provides, in some aspects, methods and compositions for producing nucleic acid nanostructures having little to no kinetic barriers to self-assembly. |
| FILED | Tuesday, April 11, 2017 |
| APPL NO | 16/092802 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0042 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 1/6811 (20130101) C12Q 2563/155 (20130101) C12Q 2563/155 (20130101) C12Q 2563/157 (20130101) C12Q 2563/157 (20130101) C12Q 2565/133 (20130101) C12Q 2565/133 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235977 | Tse et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Stephen D. Tse (Warren, New Jersey); Hua Hong (Weehawken, New Jersey); Bernard H. Kear (Whitehouse Station, New Jersey) |
| ABSTRACT | Methods for the production of carbon-based and other nanostructures are provided. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/229055 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236023 | Whalen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HONEYWELL INTERNATIONAL INC. (Morris Plains, New Jersey) |
| ASSIGNEE(S) | HONEYWELL INTERNATIONAL INC. (Charlotte, North Carolina) |
| INVENTOR(S) | Terence Whalen (Morristown, New Jersey); Bahram Jadidian (Watchung, New Jersey); Reza Oboodi (Morris Plains, New Jersey) |
| ABSTRACT | A method for forming a protective coating on a surface of a ceramic substrate includes combining a rare-earth oxide, alumina, and silica to form a powder, etching the surface of the ceramic substrate, applying the powder on the etched surface in an amount of from about 0.001 to about 0.1 g/cm2 to reduce capture of bubbles from off-gassing of the ceramic substrate, heating the powder for a time of from about 5 to about 60 minutes to a temperature at or above the melting point such that the powder melts and forms a molten coating on the surface that has a minimized number of bubbles, and cooling the molten coating to ambient temperature to form the protective coating disposed on and in direct contact with the surface of the ceramic substrate such that the protective coating has a thickness of less than about 1 mil. |
| FILED | Wednesday, November 07, 2018 |
| APPL NO | 16/183276 |
| ART UNIT | 1796 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Chemical Composition of Glasses, Glazes or Vitreous Enamels; Surface Treatment of Glass; Surface Treatment of Fibres or Filaments Made From Glass, Minerals or Slags; Joining Glass to Glass or Other Materials C03C 8/02 (20130101) C03C 8/16 (20130101) C03C 2209/00 (20130101) Lime, Magnesia; Slag; Cements; Compositions Thereof, e.g Mortars, Concrete or Like Building Materials; Artificial Stone; Ceramics; Refractories; Treatment of Natural Stone C04B 35/584 (20130101) C04B 41/009 (20130101) C04B 41/86 (20130101) C04B 41/89 (20130101) C04B 41/91 (20130101) C04B 41/522 (20130101) C04B 41/4523 (20130101) C04B 41/5022 (20130101) Original (OR) Class C04B 41/5353 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236149 | Watters et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| ASSIGNEE(S) | PRESIDENT AND FALLOWS OF HARVARD COLLEGE (Cambridge, Massachusetts) |
| INVENTOR(S) | Alexander Watters (North Andover, Massachusetts); Brendon Dusel (West Roxbury, Massachusetts); Michael Super (Lexington, Massachusetts); Mark Cartwright (West Newton, Massachusetts); Donald E. Ingber (Boston, Massachusetts) |
| ABSTRACT | Described herein are engineered microbe-targeting molecules, microbe-targeting articles, kits comprising the same, and uses thereof. Such microbe-targeting molecules, microbe-targeting articles, or the kits comprising the same can not only bind or capture of a microbe or microbial matter thereof, but they also have improved capability (e.g., enhanced sensitivity or signal intensity) of detecting a microbe or microbial matter. Thus, the microbe-targeting molecules, microbe-targeting articles, and/or the kit described herein can be used in various applications, e.g., but not limited to assays for detection of a microbe or microbial matter, diagnostic and/or therapeutic agents for diagnosis and/or treatment of an infection caused by microbes in a subject or any environmental surface, and/or devices for removal of a microbe or microbial matter from a fluid. |
| FILED | Wednesday, May 20, 2020 |
| APPL NO | 16/879015 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/00 (20130101) C07K 14/78 (20130101) Original (OR) Class C07K 14/4726 (20130101) C07K 19/00 (20130101) C07K 2319/30 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/569 (20130101) G01N 2333/78 (20130101) G01N 2400/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236151 | Bu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE USA, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. (Bethesda, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Maryland); The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Wei Bu (Potomac, North Dakota); Masaru Kanekiyo (Chevy Chase, Maryland); Michael Gordon Joyce (Washington, District of Columbia); Jeffrey I. Cohen (Silver Spring, Maryland) |
| ABSTRACT | Antibodies and compositions of matter useful for the detection, diagnosis and treatment of Epstein Barr Virus infection in mammals, and to methods of using those compositions of matter for the same. Also disclosed are proteins, referred to as anti-gp350 antibody probes, and anti-gp350 B-cell probes, that maintain the epitope structure of the CR2-binding region of gp350, but do not bind CR2. |
| FILED | Wednesday, April 25, 2018 |
| APPL NO | 16/608386 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Peptides C07K 14/05 (20130101) C07K 16/085 (20130101) Original (OR) Class C07K 2317/10 (20130101) C07K 2317/21 (20130101) C07K 2317/565 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236370 | Lynch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Zhixia Ye (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure provides compositions and methods for rapid production of chemicals in genetically engineered microorganisms in a large scale. Also provided herein is a high-throughput metabolic engineering platform enabling the rapid optimization of microbial production strains. The platform, which bridges a gap between current in vivo and in vitro bio-production approaches, relies on dynamic minimization of the active metabolic network. |
| FILED | Wednesday, October 23, 2019 |
| APPL NO | 16/661010 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0016 (20130101) C12N 9/0051 (20130101) C12N 9/1025 (20130101) C12N 15/746 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) Original (OR) Class C12P 13/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236382 | Connolly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Integrated Nano-Technologies, Inc. (Henrietta, New York) |
| ASSIGNEE(S) | Integrated Nano-Technologies, LLC (Henrietta, New York) |
| INVENTOR(S) | Dennis M. Connolly (Rochester, New York); Tara Holz (Henrietta, New York); Vera Tannous (Penfield, New York); Christopher Kilcoin (Boulder Creek, California); Konstantin Aptekarev (Santa Cruz, California); David B. Bailey (Webster, New York); Richard S. Murante (Henrietta, New York); Nathaniel E. Wescott (West Henrietta, New York) |
| ABSTRACT | A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic nanoparticles are used to concentrate and clean the nucleic acid molecules for further testing. |
| FILED | Friday, June 28, 2019 |
| APPL NO | 16/457602 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 2200/0631 (20130101) B01L 2300/0681 (20130101) Apparatus for Enzymology or Microbiology; C12M 47/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/066 (20130101) C12N 15/10 (20130101) C12N 15/1013 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/6806 (20130101) C12Q 1/6825 (20130101) Original (OR) Class C12Q 2531/113 (20130101) C12Q 2563/107 (20130101) C12Q 2563/143 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) G01N 2001/2866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236395 | Petrovics et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| ASSIGNEE(S) | The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (Bethesda, Maryland) |
| INVENTOR(S) | Gyorgy Petrovics (Bethesda, Maryland); Shiv Srivastava (Potomac, Maryland) |
| ABSTRACT | The present invention relates to oncogenes or tumor suppressor genes, as well as other genes, involved in prostate cancer and their expression products, as well as derivatives and analogs thereof. Provided are therapeutic compositions and methods of detecting and treating cancer, including prostate and other related cancers. Also provided are methods of diagnosing and/or prognosing prostate cancer by determining the expression level of at least one prostate cancer-cell-specific gene, including, for example, the ERG gene or the LTF gene alone, or in combination with at least one of the AMACR gene and the DD3 gene. |
| FILED | Friday, May 11, 2018 |
| APPL NO | 15/977443 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Peptides C07K 16/30 (20130101) C07K 16/32 (20130101) C07K 2317/33 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) C12Q 2600/158 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 999/99 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236500 | Peterson |
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| FUNDED BY |
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| APPLICANT(S) | Folding Holdings, LLC (Bothell, Washington) |
| ASSIGNEE(S) | Folding Holdings, LLC (Bothell, Washington) |
| INVENTOR(S) | Elliot Peterson (Bothell, Washington) |
| ABSTRACT | A built-up beam includes a pair of I-beams each having opposing flanges, a web that extends between the opposing flanges, a plurality of flange openings in each of the opposing flanges, a plurality of web openings in the web, and a plurality of bolt holes in one of the opposing flanges. The I-beams are stacked together flange-to-flange in a stacked beam configuration and a plurality of bolts extend through the plurality of bolt holes and secure the pair of I-beams together in the stacked beam configuration. |
| FILED | Wednesday, April 29, 2020 |
| APPL NO | 16/862411 |
| ART UNIT | 3726 — Manufacturing Devices & Processes, Machine Tools & Hand Tools Group Art Units |
| CURRENT CPC | Metal-working Not Otherwise Provided For; Combined Operations; Universal Machine Tools B23P 13/02 (20130101) B23P 15/00 (20130101) General Building Constructions; Walls, e.g Partitions; Roofs; Floors; Ceilings; Insulation or Other Protection of Buildings E04B 1/19 (20130101) Original (OR) Class Structural Elements; Building Materials E04C 3/04 (20130101) E04C 3/14 (20130101) E04C 2003/0413 (20130101) E04C 2003/0452 (20130101) E04C 2003/0465 (20130101) Technical Subjects Covered by Former US Classification Y10T 29/49364 (20150115) Y10T 29/49963 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236791 | Nguyen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Raytheon Company (Waltham, Massachusetts) |
| ASSIGNEE(S) | Raytheon Company (Waltham, Massachusetts) |
| INVENTOR(S) | Ly Dinh Nguyen (Cypress, Texas); Stevie Alejandro (Sahuarita, Arizona) |
| ABSTRACT | An energy damping and displacement control device is disclosed. The energy damping and displacement control device can include a contact protrusion and an energy damping pad constructed of a resilient material. The energy damping pad can have a first face oriented along a first plane. The energy damping pad can also have a second face oriented along a second plane transverse to the first plane, and toward the contact protrusion. In a static condition, the first and second faces of the energy damping pad can be separated from the contact protrusion. In a dynamic condition, displacement motion of the contact protrusion relative to the energy damping pad can be limited by contact with at least one of the first or second faces of the energy damping pad, which provides energy damping and motion displacement control of the contact protrusion in multiple axes. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 16/657859 |
| ART UNIT | 3657 — Material and Article Handling |
| CURRENT CPC | Springs; Shock-absorbers; Means for Damping Vibration F16F 1/065 (20130101) Original (OR) Class F16F 1/374 (20130101) F16F 15/085 (20130101) F16F 2230/007 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236955 | Monacchio et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Hamilton Sundstrand Corporation (Charlotte, North Carolina) |
| ASSIGNEE(S) | HAMILTON SUNDSTRAND CORPORATION (Charlotte, North Carolina) |
| INVENTOR(S) | John D. Monacchio (Windsor Locks, Connecticut); Eric Chrabascz (Longmeadow, Massachusetts); Luke J. Mayo (Coventry, Connecticut); John H. Whiton (South Windsor, Connecticut); Robert H. Dold (Monson, Massachusetts); Christopher Adriaan van Oss (Wethersfield, Connecticut); Usman Khan (South Windsor, Connecticut) |
| ABSTRACT | An outlet manifold is provided and includes an outlet portion having first and second sides and an inlet portion to which the outlet portion is fluidly coupled. The inlet portion has first and second sides corresponding to the first and second sides of the outlet portion. Each of the first and second sides of the inlet portion includes one or more tubular members connectable with corresponding tube joints and a mixing chamber fluidly interposed between each of the one or more tubular members and the outlet portion. |
| FILED | Tuesday, December 29, 2020 |
| APPL NO | 17/136694 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-flow Silencers or Exhaust Apparatus for Machines or Engines in General; Gas-flow Silencers or Exhaust Apparatus for Internal Combustion Engines F01N 13/06 (20130101) F01N 13/10 (20130101) F01N 13/107 (20130101) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 9/0275 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237089 | Lin et al. |
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| FUNDED BY |
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| APPLICANT(S) | Hai Lin (Rancho Cucamonga, California); Gregor Arthur Waldherr (Rancho Cucamonga, California) |
| ASSIGNEE(S) | Hal Technology, LLC (Fontana, California) |
| INVENTOR(S) | Hai Lin (Rancho Cucamonga, California); Gregor Arthur Waldherr (Rancho Cucamonga, California) |
| ABSTRACT | Disclosed herein is a novel, compact, real time optical particle identification and characterization system and method of use within both gaseous and liquid media. The system can implement elastic and/or inelastic light scattering techniques simultaneously and complimentarily under the same sensor platform. By separating the sensing components from the electro-optical unit and using optical fibers for interconnection, only the sensing components need to be exposed to the environmental conditions. This reduces the design constraints on the electro-optical unit and permits the incorporation of optical components into the sensor probe that can withstand high-temperature, high-pressure, and corrosive environments. Thus, the system can be used in benign, moderate, and harsh environments. |
| FILED | Friday, February 08, 2019 |
| APPL NO | 16/271755 |
| ART UNIT | 2877 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/0205 (20130101) Original (OR) Class G01N 2015/1087 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237091 | Hering et al. |
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| FUNDED BY |
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| APPLICANT(S) | Aerosol Dynamics Inc. (Berkeley, California) |
| ASSIGNEE(S) | Aerosol Dynamics Inc. (Berkeley, California) |
| INVENTOR(S) | Susanne Vera Hering (Berkeley, California); Arantzazu Eiguren Fernandez (Richmond, California); Gregory Stephen Lewis (Berkeley, California); Steven Russel Spielman (Oakland, California); Philip Bourgeois (Woodside, California) |
| ABSTRACT | A particle growth apparatus includes a temperature-controlled humidifier coupled to a water-based condensation growth system. The humidifier may include a tube of sulfonated tetrafluoroethylene-based fluoropolymer-copolymer and surrounded by a region containing water or water vapor. The apparatus includes a wetted wick and wick sensor in the condensation growth system, configured such that the gas sample flows through the sulfonated tetrafluoroethylene-based fluoropolymer-copolymer tube into the condensation growth system. |
| FILED | Friday, November 01, 2019 |
| APPL NO | 16/671594 |
| ART UNIT | 1776 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Air-conditioning; Air-humidification; Ventilation; Use of Air Currents for Screening F24F 6/043 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 15/065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237143 | Gregory et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute Of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute Of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Kerin E. Gregory (Bolton, Massachusetts); Roderick R. Kunz (Acton, Massachusetts); Michael Sworin (Marlboro, Massachusetts) |
| ABSTRACT | Reagents and methods are disclosed for detection of oxidizers and inorganic salts and other analytes of interest. The reagents can interact with their target analytes, especially oxidizer compositions or oxidizer-based explosives, to selectively enhance their ionization yield, interacting by chemical reaction or by forming an associative adduct which facilitates their detection. For example, the reagents can adduct with the counter-ion of the intended analyte for improved direct detection and/or react chemically via acid-base reactions to produce a new product for detection. In another aspect of the invention, reactive reagents and methods are also disclosed that facilitate indirect detection of the analyte at lower temperatures based on reduction-oxidation (redox) chemistry. These reagents are particularly useful in detecting oxidizer analytes. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/435733 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) G01N 31/227 (20130101) G01N 33/227 (20130101) Original (OR) Class G01N 2001/028 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/19 (20150115) Y10T 436/24 (20150115) Y10T 436/141111 (20150115) Y10T 436/143333 (20150115) Y10T 436/173076 (20150115) Y10T 436/206664 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237171 | Walt et al. |
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| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | TRUSTEES OF TUFTS COLLEGE (Medford, Massachusetts) |
| INVENTOR(S) | David R. Walt (Boston, Massachusetts); David M. Rissin (Somerville, Massachusetts) |
| ABSTRACT | Arrays of single molecules and methods of producing an array of single molecules are described. Arrays with defined volumes between 10 attoliters and 50 picoliters enable single molecule detection and quantitation. |
| FILED | Wednesday, February 27, 2019 |
| APPL NO | 16/286811 |
| ART UNIT | 1645 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6837 (20130101) C12Q 1/6837 (20130101) C12Q 2527/143 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/543 (20130101) G01N 33/581 (20130101) Original (OR) Class G01N 33/54346 (20130101) G01N 33/54366 (20130101) G01N 33/54386 (20130101) G01N 2333/938 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237327 | Meade |
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| FUNDED BY |
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| APPLICANT(S) | Micron Technology, Inc. (Boise, Idaho) |
| ASSIGNEE(S) | Micron Technology, Inc. (Boise, Idaho) |
| INVENTOR(S) | Roy E. Meade (Oakland, California) |
| ABSTRACT | Disclosed are a method and structure providing a silicon-on-insulator substrate on which photonic devices are formed and in which a core material of a waveguide is optically decoupled from a support substrate by a shallow trench isolation region. |
| FILED | Friday, August 16, 2019 |
| APPL NO | 16/543446 |
| ART UNIT | 2874 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/122 (20130101) G02B 6/136 (20130101) Original (OR) Class G02B 2006/12061 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 21/84 (20130101) H01L 21/76283 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237337 | Ruffa |
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| FUNDED BY |
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| APPLICANT(S) | The United States of America as represented by the Secretary of the Navy (Newport, Rhode Island) |
| ASSIGNEE(S) | The United States of America as represented by the Secretary of the Navy (, None) |
| INVENTOR(S) | Anthony A Ruffa (Hope Valley, Rhode Island) |
| ABSTRACT | A non-rotary joint for connecting a static component to a rotatable component includes an adapter on a rotatable part. A motor is joined to rotate the rotatable part. A connector is joined to the static component. The connector can be moved by an actuator from a first position joined with the adapter to a second position positioned away from the adapter. A controller is joined to control the motor and the actuator. The controller signals the actuator to move to the second position when the motor is activated and signals the actuator to move to the first position when said motor is deactivated. In a practical embodiment, the non-rotary joint makes a connection between a static signal carrier and a cable on a winch drum. |
| FILED | Wednesday, October 21, 2020 |
| APPL NO | 17/075796 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/3604 (20130101) Original (OR) Class G02B 6/3825 (20130101) Installation of Electric Cables or Lines, or of Combined Optical and Electric Cables or Lines H02G 1/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237344 | Vermeulen et al. |
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| FUNDED BY |
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| APPLICANT(S) | Analog Photonics LLC (Boston, Massachusetts) |
| ASSIGNEE(S) | Analog Photonics LLC (Boston, Massachusetts) |
| INVENTOR(S) | Diedrik Vermeulen (Boston, Massachusetts); Ehsan Shah Hosseini (Milton, Massachusetts); Michael J. Whitson (Salem, Massachusetts) |
| ABSTRACT | A first photonic die has a first coupling edge and a first die surface, and comprises: a first waveguide extending in proximity to the first coupling edge; a portion of the first die surface forming an alignment edge substantially parallel to the first waveguide; and a first alignment feature etched into or formed adjacent to the first coupling edge. A second photonic die has a second coupling edge and a second die surface, and comprises: a second waveguide extending in proximity to the second coupling edge; a portion of the second die surface configured to form a receptacle sized to constrain a position of the alignment edge; and a second alignment feature etched into or formed adjacent to the second coupling edge and configured to enable alignment with the first alignment feature when the first photonic die and the second photonic die are substantially aligned with each other. |
| FILED | Wednesday, March 11, 2020 |
| APPL NO | 16/815655 |
| ART UNIT | 2883 — Optics |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 6/4206 (20130101) G02B 6/4214 (20130101) G02B 6/4232 (20130101) Original (OR) Class G02B 6/4238 (20130101) G02B 6/4274 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237370 | Han et al. |
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| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | Kyu Young Han (Orlando, Florida); Jialei Tang (Oviedo, Florida) |
| ABSTRACT | A dual inclined beam line-scanning confocal microscope apparatus, associated method, and applications thereof. An embodied dual-inclined beam line-scanning confocal microscope (2iLS) utilizes dual, parallel excitation beams each having a focused line shape that are scanned over a fluorescent sample. The emitted fluorescence from the sample is spatially filtered and detected by an array detector. 2iLS microscopy provides high resolution, ultrasensitivity, and deep optical sectioning capability. A reduced excitation intensity lowers photobleaching and photodamage. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 16/398630 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 21/02 (20130101) G02B 21/008 (20130101) G02B 21/0032 (20130101) G02B 21/0036 (20130101) G02B 21/36 (20130101) G02B 21/0048 (20130101) G02B 21/0076 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237454 | Carolan et al. |
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| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Jacques Johannes Carolan (Cambridge, Massachusetts); Uttara Chakraborty (Cambridge, Massachusetts); Nicholas C. Harris (Boston, Massachusetts); Mihir Pant (Mountain View, California); Dirk Robert Englund (Brookline, Massachusetts) |
| ABSTRACT | Typically, quantum systems are very sensitive to environmental fluctuations, and diagnosing errors via measurements causes unavoidable perturbations. Here, an in situ frequency-locking technique monitors and corrects frequency variations in single-photon sources based on resonators. By using the classical laser fields used for photon generation as probes to diagnose variations in the resonator frequency, the system applies feedback control to correct photon frequency errors in parallel to the optical quantum computation without disturbing the physical qubit. Our technique can be implemented on a silicon photonic device and with sub 1 pm frequency stabilization in the presence of applied environmental noise, corresponding to a fractional frequency drift of <1% of a photon linewidth. These methods can be used for feedback-controlled quantum state engineering. By distributing a single local oscillator across a one or more chips, our approach enables frequency locking of many single photon sources for large-scale photonic quantum technologies. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/680908 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices or Arrangements, the Optical Operation of Which Is Modified by Changing the Optical Properties of the Medium of the Devices or Arrangements for the Control of the Intensity, Colour, Phase, Polarisation or Direction of Light, e.g Switching, Gating, Modulating or Demodulating; Techniques or Procedures for the Operation Thereof; Frequency-changing; Non-linear Optics; Optical Logic Elements; Optical Analogue/digital Converters G02F 1/365 (20130101) G02F 1/3501 (20130101) Original (OR) Class G02F 1/3551 (20130101) G02F 2201/06 (20130101) G02F 2202/20 (20130101) G02F 2202/101 (20130101) G02F 2203/50 (20130101) Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 3/13 (20130101) H01S 3/23 (20130101) H01S 3/083 (20130101) H01S 3/1628 (20130101) H01S 3/1671 (20130101) H01S 3/06791 (20130101) H01S 3/08018 (20130101) H01S 3/094003 (20130101) H01S 3/094096 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237551 | Holden et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Daniel P. Holden (Fredericksburg, Virginia); Sean R. Chapin (Richmond, Virginia); Lynda R. Hester (Fredericksburg, Virginia); Victoria Snyder (Fredericksburg, Virginia) |
| ASSIGNEE(S) | United States of America, as represented by the Secretary of the Navy (Arlington, Virginia) |
| INVENTOR(S) | Daniel P. Holden (Fredericksburg, Virginia); Sean R. Chapin (Richmond, Virginia); Lynda R. Hester (Fredericksburg, Virginia); Victoria Snyder (Fredericksburg, Virginia) |
| ABSTRACT | A computer-implemented system is provided for monitoring an electro-mechanical device. The system includes a sensor, a data acquisition receiver, and an analysis processor. The sensor measures a parameter of the device as an analog signal. The data acquisition receiver converts the analog signal into a digital signal. The analysis processor assigns the signal data to a condition state responsive to an action mode to control the device. The system is intended for automated implementation in real-time. |
| FILED | Tuesday, February 12, 2019 |
| APPL NO | 16/273756 |
| ART UNIT | 2864 — Printing/Measuring and Testing |
| CURRENT CPC | Control or Regulating Systems in General; Functional Elements of Such Systems; Monitoring or Testing Arrangements for Such Systems or Elements G05B 19/0428 (20130101) G05B 23/0283 (20130101) G05B 23/0291 (20130101) Original (OR) Class Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/6265 (20130101) Computer Systems Based on Specific Computational Models G06N 7/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237616 | Shah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Parth Sanjaybhai Shah (Bangalore, India); Ranjal Gautham Shenoy (Bangalore, India); Vaidyanathan Srinivasan (Bangalore, India); Alper Buyuktosunoglu (White Plains, New York); Augusto Vega (Mount Vernon, New York); Pradip Bose (Yorktown Heights, New York) |
| ABSTRACT | A method, computer program product, and/or system associates a number of tokens with a plurality of frequency domains (for example, cores) of a central processing unit (CPU) computer chip. The number of tokens allotted to the CPU is based on the CPU power budget. Cores are organized as a ring topology. A token pool traverses the ring, picks up excess tokens from cores having excess tokens, and gives the tokens to cores that need additional tokens. Tokens acquired by a core allows the core to increase operating frequency by an increment represented by the tokens. Consequently, power usage is weighted toward heavily loaded cores and away from lightly loaded cores. Overall power usage of the CPU remains within a power budget. The method budgets power optimally to sustain turbo frequencies for longer durations by not allowing control units to increase frequency in absence of any useful high frequency benefiting workload. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/940171 |
| ART UNIT | 2186 — Computer Architecture and I/O |
| CURRENT CPC | Electric Digital Data Processing G06F 1/263 (20130101) G06F 1/324 (20130101) Original (OR) Class G06F 1/3237 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237933 | Riabov et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Anton V. Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (Port Chester, New York); Octavian Udrea (Ossining, New York) |
| ABSTRACT | Techniques for solving a multi-agent plan recognition problem are provided. In one example, a computer-implemented method comprises transforming, by a device operatively coupled to a processor, a problem model and an at least partially ordered sequence of observations into an artificial intelligence planning problem through a transform algorithm. The problem model can comprises a domain description from a plurality of agents and a durative action. Furthermore, at least one of the observations of the at least partially ordered sequence of observations can be a condition that changes over time. The computer-implemented method further comprises determining, by the device, plan information using an artificial intelligence planner on the artificial intelligence planning problem. The computer-implemented method further comprises translating, by the device, the plan information into information indicative of a solution to the artificial intelligence planning problem. |
| FILED | Thursday, December 14, 2017 |
| APPL NO | 15/842449 |
| ART UNIT | 2488 — Recording and Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4862 (20130101) G06F 11/302 (20130101) Original (OR) Class G06F 11/3006 (20130101) G06F 11/3438 (20130101) G06F 16/951 (20190101) Computer Systems Based on Specific Computational Models G06N 5/043 (20130101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238196 | Bolander et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Sentient Science Corporation (Buffalo, New York) |
| ASSIGNEE(S) | Sentient Science Corporation (Buffalo, New York) |
| INVENTOR(S) | Nathan Bolander (Idaho Falls, Idaho); Rajasekhar V. Pulikollu (Nashville, Tennessee); Behrooz Jalalahmadi (Idaho Falls, Idaho) |
| ABSTRACT | A system and method for determining surface contact fatigue life may use a finite element method to determine when components, such as a power transmission component, may fail in operation. The method may generate a finite element model based on the material parameters related to a power transmission component, generate a surface pressure time history for a loading event based on one or more loading parameters, determine, based on the surface pressure time history for a loading event, a finite element solution that describes stress in the grain structure, calculate damage in the finite element solution using a damage model, and determine whether a damage threshold is exceeded. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/680728 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Gearing F16H 2057/0087 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 13/022 (20130101) Electric Digital Data Processing G06F 17/18 (20130101) G06F 30/23 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238327 | Paidimarri et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Arun Paidimarri (White Plains, New York); Bodhisatwa Sadhu (Peekskill, New York); Duixian Liu (Scarsdale, New York); Alberto Valdes Garcia (Chappaqua, New York) |
| ABSTRACT | A radio frequency identification (RFID) system. An RFID tag may include multiple antennas connected with associated circuitry. An RFID tag's multiple antennas and associated circuitry are connected in parallel, and output power of the multiple associated circuitry can be combined. Each of the multiple antennas can be tuned for a different operating property or region. An RFID reader can include multiple antennas connected with associated circuitry. RFID reader's multiple antenna interfaces connect with a baseband processor, which can integrate resources of the reader's multiple antennas and associated circuitry. RFID tag and/or reader can be configured to support wireless channel diversity in enhancing at least one of power delivery and communication link budget. |
| FILED | Monday, December 28, 2020 |
| APPL NO | 17/134810 |
| ART UNIT | 2887 — Optics |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 7/0008 (20130101) G06K 19/0773 (20130101) G06K 19/0775 (20130101) Original (OR) Class G06K 19/07796 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238343 | Arthur et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | John V. Arthur (Mountain View, California); Steven K. Esser (San Jose, California); Paul A. Merolla (Palo Alto, California); Dharmendra S. Modha (San Jose, California) |
| ABSTRACT | Embodiments of the invention relate to a scalable neural hardware for the noisy-OR model of Bayesian networks. One embodiment comprises a neural core circuit including a pseudo-random number generator for generating random numbers. The neural core circuit further comprises a plurality of incoming electronic axons, a plurality of neural modules, and a plurality of electronic synapses interconnecting the axons to the neural modules. Each synapse interconnects an axon with a neural module. Each neural module receives incoming spikes from interconnected axons. Each neural module represents a noisy-OR gate. Each neural module spikes probabilistically based on at least one random number generated by the pseudo-random number generator unit. |
| FILED | Friday, November 30, 2018 |
| APPL NO | 16/206738 |
| ART UNIT | 2198 — Optics |
| CURRENT CPC | Electric Digital Data Processing G06F 7/582 (20130101) Computer Systems Based on Specific Computational Models G06N 3/04 (20130101) G06N 3/08 (20130101) Original (OR) Class G06N 3/063 (20130101) G06N 3/0472 (20130101) G06N 7/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238361 | Wei et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Xuan Wei (White Plains, New York); Sarah Elizabeth Sheldon (Tarrytown, New York); Maika Takita (Hudson, New York); Jay Michael Gambetta (Yorktown Heights, New York) |
| ABSTRACT | An embodiment includes (CR) gate having a first control qubit coupled with a first target qubit, and a second CR gate having a second control qubit coupled with a second target qubit and the first control qubit. The embodiment also includes controller circuitry for performing operations including first and second iterations of: during a first time period, directing respective CR pulses to the first and second control qubits; during a second time period, directing respective single qubit pulses to the first control qubit and to the second target qubit; during a third time period, directing respective CR pulses to the first and second control qubits; and during a fourth time period, directing respective single qubit pulses to the second control qubit and to the first target qubit. |
| FILED | Monday, December 21, 2020 |
| APPL NO | 17/128661 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Computer Systems Based on Specific Computational Models G06N 10/00 (20190101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238631 | Sikka et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | SRI International (Menlo Park, California) |
| ASSIGNEE(S) | SRI International (Menlo Park, California) |
| INVENTOR(S) | Karan Sikka (Lawrenceville, New Jersey); Ajay Divakaran (Monmouth Junction, New Jersey); Samyak Datta (Atlanta, Georgia) |
| ABSTRACT | A method, apparatus and system for visual grounding of a caption in an image include projecting at least two parsed phrases of the caption into a trained semantic embedding space, projecting extracted region proposals of the image into the trained semantic embedding space, aligning the extracted region proposals and the at least two parsed phrases, aggregating the aligned region proposals and the at least two parsed phrases to determine a caption-conditioned image representation and projecting the caption-conditioned image representation and the caption into a semantic embedding space to align the caption-conditioned image representation and the caption. The method, apparatus and system can further include a parser for parsing the caption into the at least two parsed phrases and a region proposal module for extracting the region proposals from the image. |
| FILED | Wednesday, April 22, 2020 |
| APPL NO | 16/855362 |
| ART UNIT | 2613 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Electric Digital Data Processing G06F 16/51 (20190101) G06F 16/56 (20190101) Image Data Processing or Generation, in General G06T 11/60 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238663 | Guckenberger et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | VR REHAB, INC. (Clermont, Florida) |
| ASSIGNEE(S) | VR REHAB, INC. (Clermont, Florida) |
| INVENTOR(S) | Elizabeth T. Guckenberger (Clermont, Florida); Ronald J. Guckenberger (Clermont, Florida) |
| ABSTRACT | Mini-Map with Gaze Guidance Line Visualization Module enables new types and classes of Human Computer Interface enhancements where the Humans can easily and simultaneously see where objects are relative within a 2D map in the foreground connected via intuitive gaze guidance lines to the same object with the Augmented Reality view. The Mini-Map is fully manipulatable position, zoom, display angle with defaults being relative to the user. |
| FILED | Friday, October 02, 2020 |
| APPL NO | 17/062218 |
| ART UNIT | 2616 — Computer Graphic Processing, 3D Animation, Display Color Attribute, Object Processing, Hardware and Memory |
| CURRENT CPC | Image Data Processing or Generation, in General G06T 11/00 (20130101) G06T 19/006 (20130101) Original (OR) Class G06T 2210/62 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239276 | Roberts et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| ASSIGNEE(S) | CALIFORNIA INSTITUTE OF TECHNOLOGY (Pasadena, California) |
| INVENTOR(S) | Gregory Roberts (Pasadena, California); Philip Camayd-Munoz (Pasadena, California); Conner Ballew (Pasadena, California); Andrei Faraon (Pasadena, California) |
| ABSTRACT | Methods to build multi-functional scattering structures while respecting tight requirements imposed by manufacturing processes are described. The described methods and devices are based on etching away wire networks embedded in 3D structures to form voids in order to perform a target function. Optimization algorithms for designing binarized devices that meet manufacturing requirements are also disclosed. |
| FILED | Friday, October 18, 2019 |
| APPL NO | 16/657640 |
| ART UNIT | 2891 — Semiconductors/Memory |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 5/0236 (20130101) G02B 5/0247 (20130101) G02B 27/0012 (20130101) G02B 27/0025 (20130101) G02B 27/0037 (20130101) G02B 27/0056 (20130101) G02B 27/0916 (20130101) G02B 27/0938 (20130101) G02B 27/0944 (20130101) G02B 27/0977 (20130101) G02B 27/4205 (20130101) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 27/14605 (20130101) H01L 27/14607 (20130101) H01L 27/14621 (20130101) H01L 27/14625 (20130101) H01L 27/14647 (20130101) H01L 27/14685 (20130101) H01L 27/14689 (20130101) Original (OR) Class H01L 31/0232 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239422 | McAlpine et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Trustees of Princeton University (Princeton, New Jersey) |
| ASSIGNEE(S) | TRUSTEES OF PRINCETON UNIVERSITY (Princeton, New Jersey) |
| INVENTOR(S) | Michael C. McAlpine (Minneapolis, Minnesota); Yong Lin Kong (Cambridge, Massachusetts) |
| ABSTRACT | Disclosed is a process whereby diverse classes of materials can be 3D printed and fully integrated into device components with active properties. An exemplary embodiment shows the seamless interweaving of five different materials, including (1) emissive semiconducting inorganic nanoparticles, (2) an elastomeric matrix, (3) organic polymers as charge transport layers, (4) solid and liquid metal leads, and (5) a UV-adhesive transparent substrate layer, demonstrating the integrated functionality of these materials. Further disclosed is a device for printing these fully integrated 3D devices. |
| FILED | Monday, February 05, 2018 |
| APPL NO | 15/888616 |
| ART UNIT | 2894 — Semiconductors/Memory |
| CURRENT CPC | Shaping or Joining of Plastics; Shaping of Material in a Plastic State, Not Otherwise Provided For; After-treatment of the Shaped Products, e.g Repairing B29C 64/112 (20170801) Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 10/00 (20141201) Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/0004 (20130101) Original (OR) Class H01L 51/0022 (20130101) H01L 51/502 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 10/549 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239429 | Yu et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida) |
| INVENTOR(S) | Zhibin Yu (Tallahassee, Florida); Junqiang Li (Tallahassee, Florida); Xin Shan (Tallahassee, Florida) |
| ABSTRACT | An emissive perovskite ternary composite thin film comprising a perovskite material, an ionic-conducting polymer and an ionic-insulating polymer is provided. Additionally, a single-layer LEDs is described using a composite thin film of organometal halide perovskite (Pero), an ionic-conducting polymer (ICP) and an ionic-insulating polymer (IIP). The LEDs with Pero-ICP-IIP composite thin films exhibit a low turn-on voltage of about 1.9V (defined at 1 cd m−2 luminance) and a luminance of about 600,000 cd m−2. |
| FILED | Monday, June 19, 2017 |
| APPL NO | 15/626759 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/0026 (20130101) H01L 51/56 (20130101) H01L 51/0077 (20130101) Original (OR) Class H01L 51/5032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239542 | Vaisband et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Boris Vaisband (Los Angeles, California); Subramanian S. Iyer (Los Angeles, California); Adeel A. Bajwa (Los Angeles, California); Arpan Dasgupta (Los Angeles, California); Arsalan Alam (Los Angeles, California) |
| ABSTRACT | A system is provided for interconnecting multiple functional dies on a single substrate, including: (1) multiple global links in the substrate; (2) multiple local links in the substrate; and (3) multiple utility dies on the substrate, wherein each of the utility dies is connected to at least one of the global links, the utility dies are configured to communicate with one another through the global links, each of the utility dies is connected to at least one of the local links and is configured to communicate with at least one of the functional dies through the at least one of the local links. In some embodiments, an antenna is integrated into the substrate. |
| FILED | Friday, September 04, 2020 |
| APPL NO | 17/013166 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/2283 (20130101) Original (OR) Class H01Q 9/0407 (20130101) H01Q 23/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239548 | Merulla |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States, as represented by the Secretary of the Army (Washington, District of Columbia) |
| INVENTOR(S) | Emanuel Merulla (Bel Air, Maryland) |
| ABSTRACT | Various embodiments are described that relate to an antenna. In one embodiment, the antenna can be a low profile, multi-band (e.g., dual band), emulated GPS constellation antenna. In one embodiment, the antenna can form a cube with two open sides and four circuit board sides. The four circuit boards can include a first hardware portion that allows functioning in a higher frequency band and a second hardware portion that allows functioning in a lower frequency band. |
| FILED | Monday, June 22, 2020 |
| APPL NO | 16/907392 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 1/38 (20130101) Original (OR) Class H01Q 5/335 (20150115) H01Q 9/27 (20130101) H01Q 21/205 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239555 | Behdad et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Nader Behdad (Oregon, Wisconsin); John H. Booske (McFarland, Wisconsin); Hung Thanh Luyen (Madison, Wisconsin) |
| ABSTRACT | A phase shift element includes a first dielectric layer, a conductive layer, a second dielectric layer, a conducting pattern layer, switches, and vertical interconnect accesses (vias). Each conductor of a plurality of conductors of the conducting pattern layer is orthogonal to two other conductors. Each switch is switchable between a conducting position and a non-conducting position. Each via is connected to a single conductor. The first conductive material reflects an electromagnetic wave incident on the conducting pattern layer and on the second dielectric layer. When a switch is in the conducting position, the switch electrically connects two conductors to each other through their respective vias. A plurality of different switch configurations of the switches provide a 2-bit phase quantization on the reflected electromagnetic wave relative to the electromagnetic wave incident on the conducting pattern layer when the electromagnetic wave is incident on the conducting pattern layer. |
| FILED | Tuesday, October 08, 2019 |
| APPL NO | 16/595961 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 3/38 (20130101) Original (OR) Class H01Q 3/247 (20130101) H01Q 15/002 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239569 | Dufilie |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Pierre A. Dufilie (Marlborough, Massachusetts) |
| ABSTRACT | Described is a stacked patch antenna array scan-capable to 55 degrees and operable over an octave or greater frequency bandwidth. |
| FILED | Friday, February 28, 2020 |
| APPL NO | 16/804814 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 5/307 (20150115) H01Q 9/0414 (20130101) H01Q 21/065 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239634 | Osinski et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | STC.UNM (Albuquerque, New Mexico) |
| ASSIGNEE(S) | UNM Rainforest Innovations (Albuquerque, New Mexico) |
| INVENTOR(S) | Marek Osinski (Albuquerque, New Mexico); Gennady A. Smolyakov (Albuquerque, New Mexico) |
| ABSTRACT | The present invention provides one or more injection-lockable whistle-geometry semiconductor ring lasers, which may be cascaded, that are integrated on a common silicon-on-insulator (SOI) substrate with a single-frequency semiconductor master laser, wherein the light output from the semiconductor master laser is used to injection-lock the first of the semiconductor ring lasers. The ring lasers can be operated in strongly injection-locked mode, while at least one of them is subjected to direct injection current modulation. |
| FILED | Tuesday, February 28, 2017 |
| APPL NO | 16/081028 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/12 (20130101) H01S 5/021 (20130101) H01S 5/22 (20130101) H01S 5/026 (20130101) H01S 5/042 (20130101) H01S 5/125 (20130101) H01S 5/0218 (20130101) H01S 5/0225 (20210101) H01S 5/1032 (20130101) Original (OR) Class H01S 5/1071 (20130101) H01S 5/1075 (20130101) H01S 5/2205 (20130101) H01S 5/3013 (20130101) H01S 5/4006 (20130101) H01S 5/04257 (20190801) H01S 5/34306 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239736 | Miesner |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Government of the United States of America (Arlington, Virginia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of the Navy (Washington, District of Columbia) |
| INVENTOR(S) | John E Miesner (Fairfax, Virginia) |
| ABSTRACT | An electromagnetic inertial force generator provides a linear output with improved compactness and reliability because it has no radial gaps and only one pair of axial gaps. Radial permanent magnet rings are directly in contact with inner and outer flux cylinders to provide magnetic bias. The magnetic bias flux flows across two axial air gaps to a supporting flux return structure. A current conducting coil drives magnetic flux across the same axial air gaps. The magnetic bias flux is in opposite directions across the two air gaps, while the coil flux across the two gaps is in the same direction. The combination of bias flux and coil flux cancels in one gap and adds in the other gap, producing a net force on an inertial mass and an equal and opposite force on the supporting structure. The resulting force is linear with current through the drive coil. |
| FILED | Thursday, October 01, 2020 |
| APPL NO | 17/060236 |
| ART UNIT | 2832 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 33/06 (20130101) Original (OR) Class H02K 33/16 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239853 | Dai et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Digital Analog Integration, Inc. (Auburn, Alabama) |
| ASSIGNEE(S) | Digital Analog Integration, Inc. (Auburn, Alabama) |
| INVENTOR(S) | Fa Dai (Auburn, Alabama); Haoyi Zhao (Auburn, Alabama); John David Irwin (Auburn, Alabama) |
| ABSTRACT | An analog-to-digital converter includes a first converter stage, a second converter stage coupled to the first converter stage to quantize a residue signal of the first converter stage, and an inter-stage converter disposed between the first and second converter stages. The inter-stage converter is configured to convert between a first domain and a second domain. The inter-stage converter is configured to process the residue signal of the first converter stage such that a range of the residue signal matches a full scale of the second converter stage. |
| FILED | Wednesday, October 28, 2020 |
| APPL NO | 17/082481 |
| ART UNIT | 2845 — Electrical Circuits and Systems |
| CURRENT CPC | Time-interval Measuring G04F 10/005 (20130101) Coding; Decoding; Code Conversion in General H03M 1/50 (20130101) H03M 1/145 (20130101) H03M 1/164 (20130101) H03M 1/1009 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11240078 | White |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Carson White (Agoura Hills, California) |
| ABSTRACT | A Continuous Phase Frequency Shift Keying modulator provided to receive a series of binary symbols having a predetermined repetition period, and generate a series of sinusoidal signals comprising in sequence: a first sinusoidal signal with a first frequency in response to each received binary symbol having a first binary value; and a second sinusoidal signal with a second frequency in response to a received binary symbol having a second binary value, where the lowest of the first and second frequencies is larger than or equal to a third of the symbol rate; wherein the sinusoidal signals are shortened or lengthened with respect to the binary symbol they respond to, such that each first sinusoidal signal comprises an integer number of half periods of said first frequency and each second sinusoidal signal comprises an integer number of half periods of said second frequency. |
| FILED | Thursday, December 31, 2020 |
| APPL NO | 17/139916 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission of Digital Information, e.g Telegraphic Communication H04L 5/0039 (20130101) H04L 27/12 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11240137 | Melodia et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Tommaso Melodia (Newton, Massachusetts); Zhangyu Guan (Chestnut Hill, Massachusetts) |
| ABSTRACT | A wireless network operating system for communication between a plurality of nodes of a network is provided. The operating system can enable an operator to define a centralized network control problem at a high level, decompose automatically the network control problem into a set of distributed subproblems, each subproblem characterizing a local behavior of a single session or a subset of sessions or a single node or a subset of nodes or a single protocol layer or a subset of protocol layers, to generate in an automated manner a set of solution algorithms, and send the set of solution algorithms to each node for execution at an associated node controller to optimize the parameters of a programmable protocol stack based on local state information at each node. A network device for use at a node in a wireless network, a method of wirelessly communicating between a plurality of nodes in a network, and a method of providing a wireless network operating system are also provided. |
| FILED | Thursday, November 29, 2018 |
| APPL NO | 16/764229 |
| ART UNIT | 2469 — Multiplex and VoIP |
| CURRENT CPC | Transmission H04B 17/309 (20150115) H04B 17/373 (20150115) H04B 17/3912 (20150115) Transmission of Digital Information, e.g Telegraphic Communication H04L 43/14 (20130101) Original (OR) Class H04L 43/0805 (20130101) H04L 43/0823 (20130101) H04L 43/0876 (20130101) Wireless Communication Networks H04W 16/18 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Science Foundation (NSF)
| US 11235067 | Xu |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Trustees of Tufts College (Medford, Massachusetts) |
| ASSIGNEE(S) | Trustees of Tufts College (Medford, Massachusetts) |
| INVENTOR(S) | Qiaobing Xu (Lexington, Massachusetts) |
| ABSTRACT | A nanocomplex, 50 to 1000 nm in size, containing a lipid-like nanoparticle formed of a cationic lipid-based compound and a modified protein formed of a protein and an anionic polymer that includes a plurality of polar groups, the lipid-like nanoparticle and the modified protein being non-covalently bonded to each other. Also disclosed are a method of preparing the above-described nanocomplex and use thereof for treating a medical condition. Further disclosed is a pharmaceutical composition containing a nanocomplex. |
| FILED | Tuesday, January 23, 2018 |
| APPL NO | 16/479344 |
| ART UNIT | 1612 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 38/45 (20130101) A61K 45/06 (20130101) A61K 47/61 (20170801) A61K 47/543 (20170801) A61K 47/6907 (20170801) A61K 47/6939 (20170801) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 5/00 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235278 | Adkins et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California); University of Southern California (Los Angeles, California) |
| INVENTOR(S) | Jess Firey Adkins (Altadena, California); William Max Berelson (Los Angeles, California); David B. Rogers (Pasadena, California) |
| ABSTRACT | Systems and methods for sequestering emissions from marine vessels are provided. Emissions (either flue gas from exhaust or CO2 carried on the ship under pressure in gas cylinders or CO2 obtained during the ships travel via capture) are mixed in a reactor with sea water (e.g., via gas exchange through head-space equilibration or bubbling through a diffuser) until a pH of 5.5 to 6.5 is obtained. Systems and reactors pump seawater through a reactor vessel containing a reaction medium (e.g., carbonates and silicates). The reactor produces an effluent that can be expelled into the ocean. The effluent produced from the result of a reaction according to embodiments has approximately twice the concentration of Dissolved Inorganic Carbon (DIC) and Alkalinity (Alk) as the incoming sea water and has an increased Ca+2 concentration above sea water. |
| FILED | Tuesday, May 26, 2020 |
| APPL NO | 16/883637 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Separation B01D 53/92 (20130101) B01D 53/346 (20130101) B01D 53/1412 (20130101) B01D 53/1475 (20130101) Original (OR) Class B01D 53/1481 (20130101) B01D 53/1493 (20130101) B01D 2252/1035 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235286 | Kumar et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE PENN STATE RESEARCH FOUNDATION (University Park, Pennsylvania) |
| ASSIGNEE(S) | The Penn State Research Foundation (University Park, Pennsylvania) |
| INVENTOR(S) | Manish Kumar (State College, Pennsylvania); Tingwei Ren (State College, Pennsylvania); Woochul Song (State College, Pennsylvania); Yu-Ming Tu (State College, Pennsylvania) |
| ABSTRACT | The present disclosure describes compositions and methods for preparing membrane protein nanosheets and two-dimensional crystals. In particular, the methods employ a solvent. A mixture of a polymer and a membrane protein is solubilized in the solvent, applied to a substrate, and subsequently dried to form the nanosheet or two-dimensional crystal. Applicants have surprisingly found that the membrane proteins maintain their structure when exposed to solvents during the short processing time utilized. |
| FILED | Thursday, May 16, 2019 |
| APPL NO | 16/414517 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Separation B01D 67/0009 (20130101) Original (OR) Class B01D 71/24 (20130101) B01D 71/52 (20130101) B01D 71/56 (20130101) B01D 71/80 (20130101) Processes for Applying Fluent Materials to Surfaces, in General B05D 1/02 (20130101) B05D 1/005 (20130101) B05D 1/40 (20130101) B05D 1/265 (20130101) B05D 3/007 (20130101) B05D 3/0254 (20130101) Peptides C07K 14/31 (20130101) C07K 14/47 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235290 | Hsiao et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (Albany, New York) |
| ASSIGNEE(S) | The Research Foundation for the State University of New York (Albany, New York) |
| INVENTOR(S) | Benjamin S. Hsiao (Setauket, New York); Hongyang Ma (East Setauket, New York) |
| ABSTRACT | Membranes are provided for use in reverse osmosis applications. Such membranes include a nanofibrous scaffold in combination with a barrier layer. The barrier layer is formed of a polymeric matrix having functionalized cellulose nanofibers incorporated therein. The membranes may, in embodiments, also include a substrate. |
| FILED | Wednesday, February 14, 2018 |
| APPL NO | 16/485510 |
| ART UNIT | 1777 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 61/025 (20130101) B01D 69/12 (20130101) Original (OR) Class B01D 71/10 (20130101) B01D 2323/39 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/441 (20130101) C02F 2103/08 (20130101) C02F 2305/08 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235307 | Chang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Ni-Bin Chang (Orlando, Florida); Martin P. Wanielista (Orlando, Florida) |
| ABSTRACT | A synergistic composition can be used to treat water containing nitrogen compounds and phosphorus compounds. The synergistic composition includes iron filings, clay particles, aluminum particles, and sand particles. The iron filings, clay particles, and aluminum particles act synergistically to remove nitrogen compounds and phosphorus compounds from water. Specifically, the clay particles attract the nitrogen compounds and the phosphorus compounds to be absorbed onto a surface of the iron filings and the clay particles. The aluminum particles react with the nitrogen compounds via an oxidation reaction to form ammonia compounds, and react with the phosphorus compounds to produce aluminum phosphate. As such, the synergistic relationship between the iron filings, clay particles, and aluminum particles remove nitrogen and phosphorus compounds from water and recover the compounds in usable forms, namely, ammonia and aluminum phosphate. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/302895 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/12 (20130101) B01J 20/103 (20130101) B01J 20/0229 (20130101) B01J 20/0248 (20130101) B01J 20/261 (20130101) B01J 20/28016 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/72 (20130101) C02F 1/281 (20130101) C02F 1/285 (20130101) C02F 1/288 (20130101) C02F 1/705 (20130101) C02F 1/5245 (20130101) C02F 2101/16 (20130101) C02F 2101/105 (20130101) C02F 2101/163 (20130101) C02F 2103/001 (20130101) C02F 2103/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235330 | Hansen et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| ASSIGNEE(S) | Kansas State University Research Foundation (Manhattan, Kansas) |
| INVENTOR(S) | Ryan R. Hansen (Manhattan, Kansas); Thomas G. Platt (Manhattan, Kansas); Andre Jacobus van der Vlies (Manhattan, Kansas) |
| ABSTRACT | Polymer hydrogels and methods for selective retrieval of microbial targets from microwells and other cell culture devices. The methods use semi-permeable, photodegradable hydrogel membranes that permit exchange of nutrients and waste products but seals motile bacteria and other microbes within microwells. Light exposure can be used to degrade the hydrogel membrane in a targeted manner and release the microbes from targeted microwells for further study. |
| FILED | Friday, October 05, 2018 |
| APPL NO | 16/753598 |
| ART UNIT | 1799 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Separation B01D 63/088 (20130101) B01D 67/0006 (20130101) B01D 71/52 (20130101) B01D 2323/30 (20130101) B01D 2323/36 (20130101) B01D 2325/36 (20130101) B01D 2325/44 (20130101) Chemical or Physical Laboratory Apparatus for General Use B01L 3/50853 (20130101) Original (OR) Class B01L 2300/044 (20130101) B01L 2300/0819 (20130101) Apparatus for Enzymology or Microbiology; C12M 23/12 (20130101) C12M 23/20 (20130101) C12M 37/04 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235361 | Quigley et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Nicole Neff (Colorado Springs, Colorado); Jack Rowbottom (Swansea, Massachusetts) |
| ABSTRACT | Described herein are embodiments of a control system that automatically (1) determines whether a gas extraction system is in a state in which landfill gas is being released into the atmosphere, and (2) automatically controls landfill gas flow to mitigate, prevent and/or stop the release of landfill gas. The control system may control a valve to control flow of landfill gas through well piping of the gas extraction system. The pressure of landfill gas in the well piping at a location upstream of the valve may indicate whether there is a risk of landfill gas being released into the atmosphere. The control system may adjust a position of the valve in response to determining that the pressure at the location upstream of the valve indicates that there is a risk of landfill gas being released into the atmosphere. |
| FILED | Monday, November 02, 2020 |
| APPL NO | 17/086987 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/02 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/30 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235466 | Gupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Satyandra Gupta (Los Angeles, California); Ariyan Kabir (Los Angeles, California); Brual Shah (Los Angeles, California) |
| ABSTRACT | Methods, systems, and platforms for automatic setup planning for a robot. The method includes sampling multiple poses in multiple dimensions within a robotic workspace. The method includes generating one or more candidate configurations based on the multiple poses. The method includes determining a score for each candidate configuration of the one or more candidate configurations. The score represents area coverage of a region of interest and at least one of an amount of setup time of the candidate configuration or an amount of energy used. The method includes determining a set of candidate configurations that has an overall area coverage that covers the region of interest based on the score for each candidate configuration. The method includes controlling a position and an orientation of the object based on the set of candidate configurations. |
| FILED | Tuesday, April 23, 2019 |
| APPL NO | 16/391676 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/163 (20130101) B25J 9/1664 (20130101) B25J 9/1666 (20130101) Original (OR) Class B25J 9/1669 (20130101) B25J 9/1692 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235467 | Gupta et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| ASSIGNEE(S) | UNIVERSITY OF SOUTHERN CALIFORNIA (Los Angeles, California) |
| INVENTOR(S) | Satyandra Gupta (Los Angeles, California); Ariyan Kabir (Los Angeles, California); Brual Shah (Los Angeles, California) |
| ABSTRACT | Methods, systems, and apparatus for automatically moving a tool attached to a robotic manipulator from a start position to a goal position. The method includes determining, using a processor, a plurality of next possible positions from the start position. The method includes selecting a second position from the plurality of next possible positions based on respective costs associated with moving the tool from the start position to each of the possible positions in the plurality of next possible positions. The method includes moving, using a plurality of actuators, the tool to the second position. The method includes determining an updated plurality of next possible positions, selecting a next position, and moving the tool to the next position until the goal position is reached. |
| FILED | Tuesday, April 23, 2019 |
| APPL NO | 16/391920 |
| ART UNIT | 3664 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Manipulators; Chambers Provided With Manipulation Devices B25J 9/163 (20130101) B25J 9/1664 (20130101) B25J 9/1666 (20130101) Original (OR) Class B25J 9/1669 (20130101) B25J 9/1692 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235972 | Gopalkrishnan et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| ASSIGNEE(S) | President and Fellows of Harvard College (Cambridge, Massachusetts) |
| INVENTOR(S) | Nikhil Gopalkrishnan (Jamaica Plain, Massachusetts); Thomas E. Schaus (Arlington, Massachusetts); Peng Yin (Brookline, Massachusetts) |
| ABSTRACT | The present disclosure provides, in some aspects, methods and compositions for producing nucleic acid nanostructures having little to no kinetic barriers to self-assembly. |
| FILED | Tuesday, April 11, 2017 |
| APPL NO | 16/092802 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Nanostructures Formed by Manipulation of Individual Atoms, Molecules, or Limited Collections of Atoms or Molecules as Discrete Units; Manufacture or Treatment Thereof B82B 3/0042 (20130101) Original (OR) Class Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 21/04 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/10 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6811 (20130101) C12Q 1/6811 (20130101) C12Q 2563/155 (20130101) C12Q 2563/155 (20130101) C12Q 2563/157 (20130101) C12Q 2563/157 (20130101) C12Q 2565/133 (20130101) C12Q 2565/133 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235977 | Tse et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rutgers, The State University of New Jersey (New Brunswick, New Jersey) |
| ASSIGNEE(S) | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (New Brunswick, New Jersey) |
| INVENTOR(S) | Stephen D. Tse (Warren, New Jersey); Hua Hong (Weehawken, New Jersey); Bernard H. Kear (Whitehouse Station, New Jersey) |
| ABSTRACT | Methods for the production of carbon-based and other nanostructures are provided. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/229055 |
| ART UNIT | 1736 — Metallurgy, Metal Working, Inorganic Chemistry, Catalyst, Electrophotography, Photolithography |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 40/00 (20130101) Non-metallic Elements; Compounds Thereof; C01B 32/184 (20170801) Original (OR) Class Indexing Scheme Relating to Structural and Physical Aspects of Solid Inorganic Compounds C01P 2002/52 (20130101) C01P 2002/82 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236130 | Ly et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | Carnegie Mellon University (Pittsburgh, Pennsylvania) |
| INVENTOR(S) | Danith H. Ly (Pittsburgh, Pennsylvania); Suresh Kumar Gopalsamy (Tamilnadu, India); Arunava Manna (Pittsburgh, Pennsylvania) |
| ABSTRACT | Described herein are novel divalent nucleobases that each bind two nucleic acid strands, matched or mismatched when incorporated into a nucleic acid or nucleic acid analog backbone (a genetic recognition reagent, or genetic recognition reagent). In one embodiment, the genetic recognition reagent is a peptide nucleic acid (PNA) or gamma PNA (γPNA) oligomer. Uses of the divalent nucleobases and monomers and genetic recognition reagents containing the divalent nucleobases also are provided. |
| FILED | Wednesday, June 19, 2019 |
| APPL NO | 16/445427 |
| ART UNIT | 1637 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 239/47 (20130101) C07D 239/54 (20130101) C07D 251/16 (20130101) C07D 471/04 (20130101) C07D 475/08 (20130101) C07D 487/04 (20130101) C07D 487/16 (20130101) Sugars; Derivatives Thereof; Nucleosides; Nucleotides; Nucleic Acids C07H 1/06 (20130101) C07H 21/04 (20130101) Peptides C07K 14/003 (20130101) Original (OR) Class Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6809 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 33/5308 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236370 | Lynch et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| ASSIGNEE(S) | DUKE UNIVERSITY (Durham, North Carolina) |
| INVENTOR(S) | Michael David Lynch (Durham, North Carolina); Zhixia Ye (Raleigh, North Carolina) |
| ABSTRACT | The present disclosure provides compositions and methods for rapid production of chemicals in genetically engineered microorganisms in a large scale. Also provided herein is a high-throughput metabolic engineering platform enabling the rapid optimization of microbial production strains. The platform, which bridges a gap between current in vivo and in vitro bio-production approaches, relies on dynamic minimization of the active metabolic network. |
| FILED | Wednesday, October 23, 2019 |
| APPL NO | 16/661010 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/001 (20130101) C12N 9/0006 (20130101) C12N 9/0008 (20130101) C12N 9/0016 (20130101) C12N 9/0051 (20130101) C12N 9/1025 (20130101) C12N 15/746 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/42 (20130101) Original (OR) Class C12P 13/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236382 | Connolly et al. |
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| FUNDED BY |
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| APPLICANT(S) | Integrated Nano-Technologies, Inc. (Henrietta, New York) |
| ASSIGNEE(S) | Integrated Nano-Technologies, LLC (Henrietta, New York) |
| INVENTOR(S) | Dennis M. Connolly (Rochester, New York); Tara Holz (Henrietta, New York); Vera Tannous (Penfield, New York); Christopher Kilcoin (Boulder Creek, California); Konstantin Aptekarev (Santa Cruz, California); David B. Bailey (Webster, New York); Richard S. Murante (Henrietta, New York); Nathaniel E. Wescott (West Henrietta, New York) |
| ABSTRACT | A method for preparing a sample by utilizing a shearing force in the presence of a size stabilizer to break apart the sample to obtain nucleic acid molecules in a usable size range. Once nucleic acid molecules are obtained, magnetic nanoparticles are used to concentrate and clean the nucleic acid molecules for further testing. |
| FILED | Friday, June 28, 2019 |
| APPL NO | 16/457602 |
| ART UNIT | 1798 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Chemical or Physical Laboratory Apparatus for General Use B01L 3/502 (20130101) B01L 2200/0631 (20130101) B01L 2300/0681 (20130101) Apparatus for Enzymology or Microbiology; C12M 47/06 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/066 (20130101) C12N 15/10 (20130101) C12N 15/1013 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/02 (20130101) C12Q 1/6806 (20130101) C12Q 1/6825 (20130101) Original (OR) Class C12Q 2531/113 (20130101) C12Q 2563/107 (20130101) C12Q 2563/143 (20130101) C12Q 2565/629 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/286 (20130101) G01N 2001/2866 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236404 | Cibula et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | KW Associates LLC (Albany, Oregon) |
| ASSIGNEE(S) | KW ASSOCIATES LLC (Albany, Oregon) |
| INVENTOR(S) | Matthew A. Cibula (Salem, Oregon); Joshua R. Motley (Corvallis, Oregon); C. Rigel Woodside (Corvallis, Oregon); Paul E. King (Albany, Oregon) |
| ABSTRACT | Sensors measure magnetic field components, and the measured fields are used to calculate and estimated transverse position of a longitudinal electric current flowing as an electric discharge across a discharge gap. Based on the estimated position, and according to a selected transverse trajectory or distribution of the estimated discharge position, magnetic fields are applied transversely across the discharge gap so as to control or alter the estimated discharge position. Inventive apparatus and methods can be employed, inter alia, during operation of a vacuum arc furnace. |
| FILED | Monday, July 27, 2020 |
| APPL NO | 16/939060 |
| ART UNIT | 2867 — Printing/Measuring and Testing |
| CURRENT CPC | Processing of Pig-iron, e.g Refining, Manufacture of Wrought-iron or Steel; Treatment in Molten State of Ferrous Alloys C21C 5/5211 (20130101) Original (OR) Class C21C 2005/5288 (20130101) Furnaces, Kilns, Ovens, or Retorts in General; Open Sintering or Like Apparatus F27B 3/28 (20130101) F27B 3/085 (20130101) Details or Accessories of Furnaces, Kilns, Ovens, or Retorts, in so Far as They Are of Kinds Occurring in More Than One Kind of Furnace F27D 7/06 (20130101) F27D 11/10 (20130101) F27D 2007/066 (20130101) Measuring Electric Variables; Measuring Magnetic Variables G01R 15/20 (20130101) G01R 33/06 (20130101) G01R 35/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236426 | Hamers et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Robert John Hamers (Madison, Wisconsin); Shuo Li (Madison, Wisconsin) |
| ABSTRACT | Methods of forming plasmonic diamond films are provided. In an embodiment, such a method comprises forming a first layer of diamond on a substrate; depositing a layer of a metal on a surface of the first layer of diamond to form an as-deposited layer of metal; exposing the as-deposited layer of metal to a plasma treatment to convert the as-deposited layer of metal to a plurality of discrete regions of the metal on the surface of the first layer of diamond; and forming a second layer of diamond on the plurality of discrete regions of metal to form the plasmonic diamond film comprising a plurality of plasmonic nanoparticles. |
| FILED | Friday, August 17, 2018 |
| APPL NO | 16/104460 |
| ART UNIT | 1715 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 23/50 (20130101) B01J 35/004 (20130101) B01J 35/0013 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 14/18 (20130101) C23C 16/06 (20130101) C23C 16/27 (20130101) C23C 16/30 (20130101) C23C 16/56 (20130101) Original (OR) Class C23C 16/274 (20130101) C23C 16/0281 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236935 | Goldfarbmuren et al. |
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| FUNDED BY |
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| APPLICANT(S) | Rebound Technologies, Inc. (Commerce City, Colorado) |
| ASSIGNEE(S) | Rebound Technologies, Inc. (Commerce City, Colorado) |
| INVENTOR(S) | Russell Goldfarbmuren (Denver, Colorado); Luke Erickson (Denver, Colorado); Josh Nelson (Bennett, Colorado); John Darrah (Winter Park, Florida); Mauricio Sanchez (Denver, Colorado); Chance Lord (Denver, Colorado) |
| ABSTRACT | Methods, systems, and device for solidification and/or solid production, such as ice production, are provided. For example, a method of solid production includes contacting a first fluid with a second fluid to facilitate solidifying the second fluid; the first fluid and the second fluid are immiscible with respect to each other. The method includes solidifying the second fluid. A solid production system includes a first fluid and a second fluid; the first fluid and the second fluid are immiscible with respect to each other. The system includes one or more surfaces configured to contact the first fluid and the second fluid with each other and to form one or more solids from the second fluid. |
| FILED | Thursday, January 23, 2020 |
| APPL NO | 16/750170 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Producing, Working or Handling Ice F25C 1/00 (20130101) F25C 1/12 (20130101) Original (OR) Class F25C 1/147 (20130101) F25C 2300/00 (20130101) F25C 2301/002 (20130101) Refrigerators; Cold Rooms; Ice-boxes; Cooling or Freezing Apparatus Not Otherwise Provided for F25D 3/005 (20130101) F25D 17/02 (20130101) F25D 2303/084 (20130101) F25D 2303/085 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237104 | Pate |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| ASSIGNEE(S) | University of Virginia Patent Foundation (Charlottesville, Virginia) |
| INVENTOR(S) | Brooks Hart Pate (Charlottesville, Virginia) |
| ABSTRACT | A chiral molecule can be defined as a molecule that has a non-superimposable mirror image. These mirror images can be referred to as enantiomers. The enantiomers generally have the same set of bond lengths and bond angles in their three-dimensional geometry. Apparatus and techniques described herein can be used to perform analysis of chiral molecules using cavity-enhanced molecular rotational spectroscopy. A sample cell can define a resonant cavity, and a sample introduction port can provide pulse jet injection of an analyte molecule and a chiral tag to allow analysis of a complex comprising the analyte and chiral tag. |
| FILED | Wednesday, October 25, 2017 |
| APPL NO | 16/344688 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 1/16 (20130101) G01J 3/30 (20130101) G01J 3/447 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/3586 (20130101) Original (OR) Class G01N 22/00 (20130101) Electric Discharge Tubes or Discharge Lamps H01J 23/20 (20130101) H01J 23/207 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237369 | Weida et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DAYLIGHT SOLUTIONS, INC. (San Diego, California) |
| ASSIGNEE(S) | DAYLIGHT SOLUTIONS, INC. (San Diego, California) |
| INVENTOR(S) | Miles James Weida (Poway, California); Timothy Day (Poway, California) |
| ABSTRACT | An imaging microscope (12) for generating an image of a sample (10) comprises a beam source (14) that emits a temporally coherent illumination beam (20), the illumination beam (20) including a plurality of rays that are directed at the sample (10); an image sensor (18) that converts an optical image into an array of electronic signals; and an imaging lens assembly (16) that receives rays from the beam source (14) that are transmitted through the sample (10) and forms an image on the image sensor (18). The imaging lens assembly (16) can further receive rays from the beam source (14) that are reflected off of the sample (10) and form a second image on the image sensor (18). The imaging lens assembly (16) receives the rays from the sample (10) and forms the image on the image sensor (18) without splitting and recombining the rays. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 16/825916 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/00 (20130101) G02B 21/0056 (20130101) Original (OR) Class G02B 21/0088 (20130101) G02B 21/088 (20130101) G02B 21/365 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237370 | Han et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (Orlando, Florida) |
| INVENTOR(S) | Kyu Young Han (Orlando, Florida); Jialei Tang (Oviedo, Florida) |
| ABSTRACT | A dual inclined beam line-scanning confocal microscope apparatus, associated method, and applications thereof. An embodied dual-inclined beam line-scanning confocal microscope (2iLS) utilizes dual, parallel excitation beams each having a focused line shape that are scanned over a fluorescent sample. The emitted fluorescence from the sample is spatially filtered and detected by an array detector. 2iLS microscopy provides high resolution, ultrasensitivity, and deep optical sectioning capability. A reduced excitation intensity lowers photobleaching and photodamage. |
| FILED | Tuesday, April 30, 2019 |
| APPL NO | 16/398630 |
| ART UNIT | 2884 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/6458 (20130101) Optical Elements, Systems, or Apparatus G02B 21/02 (20130101) G02B 21/008 (20130101) G02B 21/0032 (20130101) G02B 21/0036 (20130101) G02B 21/36 (20130101) G02B 21/0048 (20130101) G02B 21/0076 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239320 | Zhu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| ASSIGNEE(S) | The Board of Trustees of the University of Illinois (Urbana, Illinois) |
| INVENTOR(S) | Wenjuan Zhu (Champaign, Illinois); Jialun Liu (Urbana, Illinois); Hojoon Ryu (Urbana, Illinois) |
| ABSTRACT | A classifier circuit includes an array of dual gate graphene transistors, each of the transistors having a source, a top gate receiving one of an input voltage to be evaluated or a reference voltage, a bottom or embedded gate receiving the other of the input voltage or reference voltage and a drain, the source and drain contacting a graphene channel One of the source and the drain is connected to a voltage source. A common output combines output current of a plurality of the dual gate graphene transistors, which current varies in response to the difference between the input voltage and the reference voltage. A method for forming a classifier transistor with high remanent polarization forms dielectric with ferroelectric capability on a low resistivity substrate. A non-ferroelectric oxide layer is formed on the dielectric. A window is opened, and a graphene channel is formed in the window. |
| FILED | Friday, December 06, 2019 |
| APPL NO | 16/706004 |
| ART UNIT | 2896 — Semiconductors/Memory |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 29/516 (20130101) H01L 29/1606 (20130101) Original (OR) Class H01L 29/66045 (20130101) H01L 29/78391 (20140902) H01L 29/78603 (20130101) H01L 29/78618 (20130101) H01L 29/78648 (20130101) H01L 29/78684 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239429 | Yu et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Florida State University Research Foundation, Inc. (Tallahassee, Florida) |
| ASSIGNEE(S) | THE FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (Tallahassee, Florida) |
| INVENTOR(S) | Zhibin Yu (Tallahassee, Florida); Junqiang Li (Tallahassee, Florida); Xin Shan (Tallahassee, Florida) |
| ABSTRACT | An emissive perovskite ternary composite thin film comprising a perovskite material, an ionic-conducting polymer and an ionic-insulating polymer is provided. Additionally, a single-layer LEDs is described using a composite thin film of organometal halide perovskite (Pero), an ionic-conducting polymer (ICP) and an ionic-insulating polymer (IIP). The LEDs with Pero-ICP-IIP composite thin films exhibit a low turn-on voltage of about 1.9V (defined at 1 cd m−2 luminance) and a luminance of about 600,000 cd m−2. |
| FILED | Monday, June 19, 2017 |
| APPL NO | 15/626759 |
| ART UNIT | 1786 — Miscellaneous Articles, Stock Material |
| CURRENT CPC | Semiconductor Devices; Electric Solid State Devices Not Otherwise Provided for H01L 51/004 (20130101) H01L 51/0026 (20130101) H01L 51/56 (20130101) H01L 51/0077 (20130101) Original (OR) Class H01L 51/5032 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239717 | Islam et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | North Carolina State University (Raleigh, North Carolina) |
| ASSIGNEE(S) | North Carolina State University (Raleigh, North Carolina) |
| INVENTOR(S) | Md Sariful Islam (Raleigh, North Carolina); Md Ashfanoor Kabir (Raleigh, North Carolina); Iqbal Husain (Raleigh, North Carolina) |
| ABSTRACT | Various examples related to shifted fractional pitch wye-delta multilayer windings and their use in AC machines. In one example, a winding includes a first wye-delta winding with first wye and delta windings for each phase and a second wye-delta winding with second wye and delta windings for each phase. The first and second wye windings for each phase are connected in series and the first and second delta windings are connected in series, and formed wye and delta windings are connected in a wye-delta configuration thereby providing an electrical phase shift between the two windings. The windings are interdigitated to provide a physical shift between the first and second wye windings and the first and second delta windings. Such windings can be used in, e.g., permanent magnet synchronous machines, synchronous machines, reluctance machines, and induction machines. |
| FILED | Tuesday, June 11, 2019 |
| APPL NO | 16/438237 |
| ART UNIT | 2834 — Electrical Circuits and Systems |
| CURRENT CPC | Dynamo-electric Machines H02K 1/16 (20130101) H02K 3/12 (20130101) Original (OR) Class H02K 3/48 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239877 | Chopra et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | AT and T Intellectual Property I, L.P. (Atlanta, Georgia); University of Notre Dame du Lac (South Bend, Indiana) |
| ASSIGNEE(S) | AT and T INTELLECTUAL PROPERTY I, L.P. (Atlanta, Georgia); UNIVERSITY OF NOTRE DAME DU LAC (South Bend, Indiana) |
| INVENTOR(S) | Aditya Chopra (Austin, Texas); Ralf Bendlin (Cedar Park, Texas); Nicholas Joseph Estes (South Bend, Indiana); Kang Gao (San Diego, California); Bertrand Martyn Hochwald (South Bend, Indiana); Jonathan David Chisum (South Bend, Indiana) |
| ABSTRACT | Aspects of the subject disclosure may include, for example, generating multiple digital reference pulses synchronously to a master oscillator, selectively switching the multiple digital reference pulses, and providing the switched pulses to multiple radio modules operating within a millimeter wave spectrum. For each radio module, counting cycles of an adjustable LO output signal occurring between consecutive pulses of the switched digital reference pulses, determining a difference between the count value and a reference value, and adjusting the adjustable LO according to the difference. A resulting corrected LO signal is synchronized to the master oscillator. Other embodiments are disclosed. |
| FILED | Tuesday, November 24, 2020 |
| APPL NO | 17/102666 |
| ART UNIT | 2632 — Digital Communications |
| CURRENT CPC | Transmission H04B 1/0003 (20130101) H04B 1/50 (20130101) Original (OR) Class H04B 1/0082 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239963 | Melodia et al. |
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| FUNDED BY |
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| APPLICANT(S) | Northeastern University (Boston, Massachusetts) |
| ASSIGNEE(S) | Northeastern University (Boston, Massachusetts) |
| INVENTOR(S) | Tommaso Melodia (Newton, Massachusetts); Giuseppe Enrico Santagati (Cambridge, Massachusetts) |
| ABSTRACT | A system and method for transmitting data ultrasonically through biological tissue employs a network of a plurality of nodes, at least a portion of the nodes implantable within the biological tissue. At least one implanted node includes a transmitter having an orthogonal frequency division multiplex signal generator to encode an ultrasonic signal for transmission through the biological tissue to an ultrasonic receiver at another node. |
| FILED | Monday, September 28, 2020 |
| APPL NO | 17/034217 |
| ART UNIT | 2631 — Digital Communications |
| CURRENT CPC | Transmission H04B 11/00 (20130101) H04B 13/005 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 1/0003 (20130101) H04L 1/0009 (20130101) H04L 1/0057 (20130101) H04L 5/0012 (20130101) Original (OR) Class H04L 27/0008 (20130101) H04L 27/362 (20130101) H04L 27/2053 (20130101) H04L 27/2602 (20130101) H04L 27/2626 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239998 | Atallah et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| ASSIGNEE(S) | Purdue Research Foundation (West Lafayette, Indiana) |
| INVENTOR(S) | Mikhail J Atallah (West Lafayette, Indiana); Siva Chaitanya Chaduvula (Lafayette, Indiana); Adam Dachowicz (West Lafayette, Indiana); Jitesh H Panchal (West Lafayette, Indiana); Mohammad S Rahman (West Lafayette, Indiana) |
| ABSTRACT | A method of performing ordered statistics between at least two parties is disclosed which includes identifying a first dataset (xA) by a first node (A), identifying a second dataset (xB) by a second node (B), wherein xB is unknown to A and xA is unknown to B, and wherein A is in communication with B, and wherein A and B are in communication with a server (S), A and B each additively splitting each member of their respective datasets into corresponding shares, sharing the corresponding shares with one another, arranging the corresponding shares according to a mutually agreed predetermined order into corresponding ordered shares, shuffling the ordered shares into shuffled shares, re-splitting the shuffled shares into re-split shuffled shares, and performing an ordered statistical operation on the re-split shuffled shares, wherein the steps of shuffle and re-split is based on additions, subtractions but not multiplication and division. |
| FILED | Friday, August 16, 2019 |
| APPL NO | 16/543495 |
| ART UNIT | 2437 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 17/18 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/0631 (20130101) Original (OR) Class H04L 2209/46 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11240752 | Kassa et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Morgan State University (Baltimore, Maryland) |
| ASSIGNEE(S) | Morgan State University (Baltimore, Maryland) |
| INVENTOR(S) | Hailu Kassa (Nottingham, Maryland); Kevin Kornegay (Towson, Maryland) |
| ABSTRACT | Methods and systems are provided for managing a smart antenna system to maximize energy efficiency while maintaining spectral efficiency and signal integrity. In accordance with certain aspects of a particularly preferred embodiment, antenna beamforming may be optimized at a base station by combining a recursive least squares beamforming technique with Kaiser windowing functions to enable side lobe cancellation in the emitted beam, thus enhancing the capacity and service quality of smart antenna systems. With respect to further aspects of a particularly preferred embodiment, processing methods may be implemented at the base station of a cellular network to cluster mobile stations in a way that improves overall energy efficiency of a base station in the cellular network. More particularly, mobile stations or users may be clustered using a linear radius clustering method and a last user sector based clustering method to direct the beam emitted from the base station antenna to those sectors determined to contain the users having the greatest signal resource need. |
| FILED | Tuesday, February 04, 2020 |
| APPL NO | 16/781480 |
| ART UNIT | 2412 — Multiplex and VoIP |
| CURRENT CPC | Electric Digital Data Processing G06F 9/30036 (20130101) Wireless Communication Networks H04W 52/46 (20130101) H04W 52/0206 (20130101) H04W 52/0212 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Energy (DOE)
| US 11234678 | Huang et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico) |
| ASSIGNEE(S) | TRIAD NATIONAL SECURITY, LLC (Los Alamos, New Mexico) |
| INVENTOR(S) | Lianjie Huang (Los Alamos, New Mexico); Zhigang Zhang (Los Alamos, New Mexico) |
| ABSTRACT | Ultrasound tomography imaging methods for imaging a tissue medium with one or more ultrasound transducer arrays comprising a plurality of transducers, wherein said transducers comprise source transducers, receiving transducers. The methods include assigning a phase value or time delay to source transducers, exciting the transducers and calculating a search direction based on data relating to the excited transducers. |
| FILED | Wednesday, July 25, 2018 |
| APPL NO | 16/045279 |
| ART UNIT | 3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Diagnosis; Surgery; Identification A61B 5/0073 (20130101) A61B 5/7275 (20130101) A61B 8/13 (20130101) A61B 8/14 (20130101) A61B 8/15 (20130101) A61B 8/085 (20130101) A61B 8/145 (20130101) A61B 8/406 (20130101) A61B 8/483 (20130101) A61B 8/0825 (20130101) A61B 8/4477 (20130101) A61B 8/4488 (20130101) A61B 8/4494 (20130101) A61B 8/5207 (20130101) Original (OR) Class Radio Direction-finding; Radio Navigation; Determining Distance or Velocity by Use of Radio Waves; Locating or Presence-detecting by Use of the Reflection or Reradiation of Radio Waves; Analogous Arrangements Using Other Waves G01S 15/8915 (20130101) G01S 15/8929 (20130101) G01S 15/8997 (20130101) Image Data Processing or Generation, in General G06T 5/001 (20130101) G06T 11/005 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235055 | Korber et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Los Alamos National Security, LLC (Los Alamos, New Mexico); Oxford University Innovation Limited (Oxford, United Kingdom) |
| ASSIGNEE(S) | Triad National Security, LLC (Los Alamos, New Mexico); Isis Innovation Limited (Oxford, United Kingdom) |
| INVENTOR(S) | Bette T. M. Korber (Los Alamos, New Mexico); Tomas Hanke (Oxford, United Kingdom); Andrew McMichael (Oxford, United Kingdom) |
| ABSTRACT | Disclosed herein are mosaic conserved region HIV polypeptides and immunogenic polypeptides including one or more of the mosaic conserved region polypeptides. In some embodiments, the immunogenic polypeptides are included in an immunogenic composition, such as a polyvalent immunogenic composition. Also disclosed herein are methods for treating or inhibiting HIV in a subject including administering one or more of the disclosed immunogenic polypeptides or compositions to a subject having or at risk of HIV infection. In some embodiments, the methods include inducing an immune response in a subject comprising administering to the subject at least one of the disclosed immunogenic polypeptides or a nucleic acid encoding at least one of the immunogenic polypeptides. |
| FILED | Friday, June 29, 2018 |
| APPL NO | 16/023871 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) Original (OR) Class Peptides C07K 14/005 (20130101) C07K 14/161 (20130101) C07K 14/162 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16034 (20130101) C12N 2740/16122 (20130101) C12N 2740/16222 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235076 | Strong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington); The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | Fred Hutchinson Cancer Research Center (Seattle, Washington); The Regents of the Universitv of California (Oakland, California) |
| INVENTOR(S) | Roland K. Strong (Seattle, Washington); Peter Rupert (Seattle, Washington); Rebecca J. Abergel (Berkeley, California); Ilya Captain (Moraga, California); Gauthier J P Deblonde (Berkeley, California) |
| ABSTRACT | Siderocalin-metal chelator combinations that bind metallic radioisotopes used in nuclear medicine with high affinity are described. The high affinity siderocalin-metal chelator combinations include a number of chelator backbone arrangements with functional groups that coordinate with metals. The siderocalin-metal chelator combinations can be used to deliver radionuclides for imaging and therapeutic purposes. |
| FILED | Monday, August 28, 2017 |
| APPL NO | 16/329178 |
| ART UNIT | 1618 — Organic Compounds: Bio-affecting, Body Treating, Drug Delivery, Steroids, Herbicides, Pesticides, Cosmetics, and Drugs |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 51/0478 (20130101) A61K 51/0482 (20130101) Original (OR) Class Separation B01D 15/34 (20130101) B01D 15/3804 (20130101) Peptides C07K 14/47 (20130101) Production and Refining of Metals; Pretreatment of Raw Materials C22B 60/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236057 | Krumm et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| ASSIGNEE(S) | REGENTS OF THE UNIVERSITY OF MINNESOTA (Minneapolis, Minnesota) |
| INVENTOR(S) | Christoph Krumm (Saint Paul, Minnesota); Kristeen Joseph (Minneapolis, Minnesota); Dae Sung Park (Minneapolis, Minnesota); Mahesh Mahanthappa (Minneapolis, Minnesota); Paul J. Dauenhauer (Sunderland, Massachusetts) |
| ABSTRACT | Disclosed are compounds of the Formula 1 wherein A is an aromatic moiety; H is a hydrophobic group comprising a main alkyl chain having from about 3 to about 26 carbon atoms and comprising a C2 or greater alkyl chain branched from the main alkyl chain; and K is a hydrophilic group. |
| FILED | Monday, November 07, 2016 |
| APPL NO | 15/773991 |
| ART UNIT | 1699 — Organic Chemistry |
| CURRENT CPC | Heterocyclic Compounds C07D 207/333 (20130101) C07D 207/337 (20130101) C07D 213/30 (20130101) C07D 213/50 (20130101) C07D 307/20 (20130101) C07D 307/36 (20130101) C07D 307/40 (20130101) C07D 307/42 (20130101) C07D 307/46 (20130101) Original (OR) Class C07D 307/64 (20130101) C07D 333/16 (20130101) C07D 333/32 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236134 | Kong et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | The Scripps Research Institute (La Jolla, California) |
| ASSIGNEE(S) | The Scripps Research Institute (La Jolla, California) |
| INVENTOR(S) | Leopold Kong (Bethesda, Maryland); Ian A. Wilson (La Jolla, California); Natalia De Val (San Diego, California); Andrew B. Ward (San Diego, California); Dennis Burton (La Jolla, California); Linling He (San Diego, California); Jiang Zhu (San Diego, California) |
| ABSTRACT | The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections. |
| FILED | Monday, February 03, 2020 |
| APPL NO | 16/780495 |
| ART UNIT | 1648 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 39/12 (20130101) A61K 39/21 (20130101) A61K 47/64 (20170801) A61K 47/6929 (20170801) A61K 2039/645 (20130101) A61K 2039/5258 (20130101) A61K 2039/6031 (20130101) Peptides C07K 14/005 (20130101) C07K 14/162 (20130101) Original (OR) Class Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 2740/16122 (20130101) C12N 2740/16134 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236196 | Bae et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| ASSIGNEE(S) | Rensselaer Polytechnic Institute (Troy, New York) |
| INVENTOR(S) | Chulsung Bae (Cohoes, New York); Woo-Hyung Lee (Siheung-Si, South Korea) |
| ABSTRACT | Embodiments of the invention relate to a novel class of polymers with superior mechanical properties and chemical stability, as compared to known polymers. These polymers are particularly well suited for use in anion exchange membranes (AEMs), including those employed in fuel cells. Novel methods for the manufacture of these polymers are also described. |
| FILED | Wednesday, February 12, 2020 |
| APPL NO | 16/788506 |
| ART UNIT | 1766 — Organic Chemistry, Polymers, Compositions |
| CURRENT CPC | Preservation of Bodies of Humans or Animals or Plants or Parts Thereof; Biocides, e.g as Disinfectants, as Pesticides or as Herbicides; Pest Repellants or Attractants; Plant Growth Regulators A01N 29/00 (20130101) Macromolecular Compounds Obtained Otherwise Than by Reactions Only Involving Unsaturated Carbon-to-carbon Bonds C08G 10/00 (20130101) C08G 61/02 (20130101) Original (OR) Class C08G 2261/20 (20130101) C08G 2261/45 (20130101) C08G 2261/124 (20130101) C08G 2261/146 (20130101) C08G 2261/312 (20130101) C08G 2261/332 (20130101) Coating Compositions, e.g Paints, Varnishes or Lacquers; Filling Pastes; Chemical Paint or Ink Removers; Inks; Correcting Fluids; Woodstains; Pastes or Solids for Colouring or Printing; Use of Materials Therefor C09D 5/14 (20130101) C09D 165/00 (20130101) Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 13/08 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 8/1004 (20130101) H01M 8/1039 (20130101) H01M 8/1072 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 70/50 (20151101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236429 | Voskian et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Sahag Voskian (Cambridge, Massachusetts); Alexander Murray (Canterbury, United Kingdom); Trevor Alan Hatton (Sudbury, Massachusetts); Yogesh Surendranath (Cambridge, Massachusetts) |
| ABSTRACT | Systems and methods for electrochemically producing chemical products are provided. In certain cases, the systems and methods described herein are capable of producing chemical products such as hydrogen peroxide in solutions with relatively low concentrations of electrolyte or other dissolved species at high efficiencies and/or low energetic cost. In some cases, redox mediators are used to temporally decouple direct electrochemical processes from the production of the chemical product. |
| FILED | Monday, June 24, 2019 |
| APPL NO | 16/450859 |
| ART UNIT | 1796 — Coating, Etching, Cleaning, Single Crystal Growth |
| CURRENT CPC | Electrolytic or Electrophoretic Processes for the Production of Compounds or Non-metals; Apparatus Therefor C25B 1/30 (20130101) C25B 9/19 (20210101) C25B 9/23 (20210101) C25B 15/08 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236863 | Ruiz-Rodriguez et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | UT-Battelle, LLC (Oak Ridge, Tennessee) |
| ASSIGNEE(S) | UT-BATTELLE, LLC (Oak Ridge, Tennessee) |
| INVENTOR(S) | Mariano M Ruiz-Rodriguez (Knoxville, Tennessee); Saad R Elorfi (Lafollette, Tennessee); Christopher M Redmon (Rockwood, Tennessee); Ryan J Morgan (Lancing, Tennessee) |
| ABSTRACT | An improved system and method for the automated refilling of cryogenic helium is provided. In one embodiment, the system includes a dewar in fluid communication with a liquid helium cryostat through a cryogen transfer line. A controller regulates operation of a three-way valve to pre-cool the transfer line and to cause gaseous helium to flow to the dewar and force liquid helium through the transfer line into the cryostat. The controller is coupled to the output of a cryogenic level sensor, such that the controller regulates the helium liquid level within the cryostat. During filling cycles, the dewar liquid level is also monitored by the cryogenic level sensor and an alarm sounds if the dewar liquid level is undesirably low. Between filling cycles, the controller is operable to ventilate the dewar through a solenoid vent valve in fixed time intervals to ensure the dewar pressure is sufficiently low so as to not bleed liquid helium into the cryostat. |
| FILED | Wednesday, December 19, 2018 |
| APPL NO | 16/225396 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Vessels for Containing or Storing Compressed, Liquefied or Solidified Gases; Fixed-capacity Gas-holders; Filling Vessels With, or Discharging From Vessels, Compressed, Liquefied, or Solidified Gases F17C 5/06 (20130101) Original (OR) Class F17C 13/025 (20130101) F17C 2221/017 (20130101) F17C 2223/033 (20130101) F17C 2223/0161 (20130101) F17C 2225/0123 (20130101) F17C 2250/043 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236953 | de Bock et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | General Electric Company (Schenectady, New York) |
| ASSIGNEE(S) | GENERAL ELECTRIC COMPANY (Schenectady, New York); U.S. DEPARTMENT OF ENERGY (Washington, District of Columbia) |
| INVENTOR(S) | Hendrik Pieter Jacobus de Bock (Clifton Park, New York); William Dwight Gerstler (Niskayuna, New York); Daniel J. Erno (Clifton Park, New York); John C. Glessner (Kings Mills, Ohio); Neil R. Garrigan (Niskayuna, New York); Jeffrey Rambo (Mason, Ohio) |
| ABSTRACT | An inverted heat exchanger device includes an exterior conduit elongated and extending around a center axis between a first end and second end. The exterior conduit including a body having an exterior surface, an interior surface, a center core elongated along the center axis, and plural walls extending between the center core and the interior surface. A first conduit is disposed inside the exterior conduit that includes an inlet, plural core passages, an outlet, and internal manifolds. A first fluid is configured to flow along the first conduit. A second conduit is also disposed inside the exterior conduit. The second conduit includes an inlet, plural core passages, an outlet, and internal manifolds. A second fluid is configured to flow along the second conduit. The plural walls are configured to define the first conduit and the second conduit within the body of the exterior conduit. |
| FILED | Friday, November 22, 2019 |
| APPL NO | 16/692728 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Additive Manufacturing, i.e Manufacturing of Three-dimensional [3-D] Objects by Additive Deposition, Additive Agglomeration or Additive Layering, e.g by 3-d Printing, Stereolithography or Selective Laser Sintering B33Y 80/00 (20141201) Details of Heat-exchange and Heat-transfer Apparatus, of General Application F28F 1/42 (20130101) Original (OR) Class F28F 7/02 (20130101) F28F 13/08 (20130101) F28F 2250/104 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238013 | Oganezov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTEL CORPORATION (Santa Clara, California) |
| ASSIGNEE(S) | INTEL CORPORATION (Santa Clara, California) |
| INVENTOR(S) | Alexander Oganezov (Portland, Oregon); Jeffrey V. Olivier (Longmont, Colorado); Christopher Holguin (Denver, Colorado) |
| ABSTRACT | Logic may pre-populate cache of compute nodes allocated to a user's session. Logic may access an image file of a global filesystem, the image file to comprise a first set of one or more files associated with a user session and a second set of one or more files upon which execution of the first set will depend. Logic may store the image file in local data storage of each compute node of a spanning tree of compute nodes allocated for the user session. Logic may unpack the image file based on the data. Logic may configure the local environment of each compute node in the spanning tree to identify a location in local memory of each of the files. And logic may initiate execution of a local filesystem service in each of the compute nodes of the spanning tree. |
| FILED | Wednesday, June 27, 2018 |
| APPL NO | 16/020906 |
| ART UNIT | 2165 — Data Bases & File Management |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4416 (20130101) G06F 16/51 (20190101) G06F 16/176 (20190101) Original (OR) Class G06F 16/9027 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238999 | Piefer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); SHINE Medical Technologies, Inc. (Janesville, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin); SHINE Medical Technologies, Inc. (Madison, Wisconsin) |
| INVENTOR(S) | Gregory Richard Piefer (Middleton, Wisconsin); Thad Alexander Heltemes (Waunakee, Wisconsin); Eric Nicholas Van Abel (Oregon, Wisconsin); Ross Francis Radel (Madison, Wisconsin) |
| ABSTRACT | An apparatus for generating medical isotopes provides an annular fissile solution vessel surrounding a neutron generator. The annular fissile solution vessel provides for good capture of the emitted neutrons and a geometry that provides enhanced stability in an aqueous reactor. A neutron multiplier and/or a neutron moderator may be used to improve the efficiency and control the criticality of the reaction in the annular fissile solution vessel. |
| FILED | Friday, June 07, 2019 |
| APPL NO | 16/434324 |
| ART UNIT | 3646 — Aeronautics, Agriculture, Fishing, Trapping, Vermin Destroying, Plant and Animal Husbandry, Weaponry, Nuclear Systems, and License and Review |
| CURRENT CPC | Conversion of Chemical Elements; Radioactive Sources G21G 1/06 (20130101) G21G 1/08 (20130101) Original (OR) Class G21G 1/10 (20130101) G21G 4/02 (20130101) G21G 2001/0036 (20130101) G21G 2001/0042 (20130101) G21G 2001/0063 (20130101) G21G 2001/0068 (20130101) Techniques for Handling Particles or Ionising Radiation Not Otherwise Provided For; Irradiation Devices; Gamma Ray or X-ray Microscopes G21K 5/08 (20130101) Plasma Technique; Production of Accelerated Electrically-charged Particles or of Neutrons; Production or Acceleration of Neutral Molecular or Atomic Beams H05H 3/06 (20130101) H05H 6/00 (20130101) H05H 2277/116 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239495 | Visco et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | PolyPlus Battery Company (Berkeley, California) |
| ASSIGNEE(S) | PolyPlus Battery Company (Berkeley, California) |
| INVENTOR(S) | Steven J. Visco (Berkeley, California); Vitaliy Nimon (San Francisco, California); Yevgeniy S. Nimon (Danville, California); Bruce D. Katz (Moraga, California) |
| ABSTRACT | Nanofilm-encapsulated sulfide glass solid electrolyte structures and methods for making the encapsulated glass structures involve a lithium ion conducting sulfide glass sheet encapsulated on its opposing major surfaces by a continuous and conformal nanofilm made by atomic layer deposition (ALD). During manufacture, the reactive surfaces of the sulfide glass sheet are protected from deleterious reaction with ambient moisture, and the nanofilm can be configured to provide additional performance advantages, including enhanced mechanical strength and improved chemical resistance. |
| FILED | Tuesday, February 04, 2020 |
| APPL NO | 16/781713 |
| ART UNIT | 1729 — Fuel Cells, Battery, Flammable Gas, Solar Cells, Liquid Crystal Compositions |
| CURRENT CPC | Specific Uses or Applications of Nanostructures; Measurement or Analysis of Nanostructures; Manufacture or Treatment of Nanostructures B82Y 30/00 (20130101) Coating Metallic Material; Coating Material With Metallic Material; Surface Treatment of Metallic Material by Diffusion into the Surface, by Chemical Conversion or Substitution; Coating by Vacuum Evaporation, by Sputtering, by Ion Implantation or by Chemical Vapour Deposition, in General C23C 16/40 (20130101) C23C 16/345 (20130101) C23C 16/45536 (20130101) Processes or Means, e.g Batteries, for the Direct Conversion of Chemical Energy into Electrical Energy H01M 4/382 (20130101) H01M 4/0421 (20130101) H01M 10/0525 (20130101) H01M 10/0562 (20130101) Original (OR) Class H01M 2300/0068 (20130101) H01M 2300/0071 (20130101) H01M 2300/0094 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239631 | Barwicz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Tymon Barwicz (Yorktown Heights, New York); Yves C. Martin (Ossining, New York); Jason S. Orcutt (Katonah, New York) |
| ABSTRACT | A method of forming a laser including device is provided that in one embodiment includes providing a laser chip including at least one ridge structure that provides an alignment features. The method further includes bonding a type IV photonics chip to the laser chip, wherein a vertical alignment feature from the type IV photonics chip is inserted in a recess relative to the at least one ridge structure that provides the alignment features of the laser structure. |
| FILED | Thursday, September 26, 2019 |
| APPL NO | 16/584218 |
| ART UNIT | 2828 — Semiconductors/Memory |
| CURRENT CPC | Devices Using the Process of Light Amplification by Stimulated Emission of Radiation [LASER] to Amplify or Generate Light; Devices Using Stimulated Emission of Electromagnetic Radiation in Wave Ranges Other Than Optical H01S 5/22 (20130101) H01S 5/0234 (20210101) H01S 5/0237 (20210101) H01S 5/02326 (20210101) H01S 5/02375 (20210101) Original (OR) Class H01S 5/04252 (20190801) H01S 2301/176 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239732 | Hagen et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | Skyler S. Hagen (Markesan, Wisconsin); Daniel Colin Ludois (Middleton, Wisconsin) |
| ABSTRACT | An electrical rotating machine, such as a generator or motor, communicates power from a stationary location to the rotating rotor of the rotating machine via opposed pairs of capacitor plates, one plate of each pair rotating with the rotor and one plate of each pair fixed not to rotate. Larger plate gaps suitable for mechanically rigid plates are possible through high-voltage and high-frequency AC signals managed by using a dielectric support design for the capacitor plates minimizing dielectric loss and/or impedance matching on the rotor. |
| FILED | Wednesday, August 07, 2019 |
| APPL NO | 16/534735 |
| ART UNIT | 2832 — Electrical Circuits and Systems |
| CURRENT CPC | Electrically-conductive Connections; Structural Associations of a Plurality of Mutually-insulated Electrical Connecting Elements; Coupling Devices; Current Collectors H01R 39/02 (20130101) Dynamo-electric Machines H02K 13/003 (20130101) Original (OR) Class H02K 13/14 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11240433 | Dayton et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| ASSIGNEE(S) | Lawrence Livermore National Security, LLC (Livermore, California) |
| INVENTOR(S) | Matthew S. Dayton (Hayward, California); John E. Field (Dorrington, California) |
| ABSTRACT | The present disclosure is directed to a snapshot multiframe imager having an aperture element having at least one aperture, an adjacently positioned random mask, an imaging element and a computer. The random mask has a plurality of micron scale apertures and receives light passing through the aperture element, which represents the spatial information from the scene being imaged, and generates a plurality of image frames encoded in a spatial domain. The imaging element may operate in a drift-scan mode receives the encoded image frames and generates a streaked pattern of electrons representing a plurality of images of the scene at a plurality of different times. The computer analyzes the streaked pattern of electrons and mathematically reconstructs the plurality of images. |
| FILED | Friday, April 24, 2020 |
| APPL NO | 16/857913 |
| ART UNIT | 2696 — Selective Visual Display Systems |
| CURRENT CPC | Pictorial Communication, e.g Television H04N 5/32 (20130101) H04N 5/372 (20130101) H04N 5/23277 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11240935 | Chainer et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | International Business Machines Corporation (Armonk, New York) |
| INVENTOR(S) | Timothy J. Chainer (Putnam Valley, New York); Pritish R. Parida (Fishkill, New York) |
| ABSTRACT | A data center cooling system is operated in a first mode, has an indoor portion wherein heat is absorbed from components in the data center by a heat transfer fluid, and has an outdoor heat exchanger portion and a geothermal heat exchanger portion. The first mode includes ambient air cooling of the heat transfer fluid in the outdoor heat exchanger portion and/or geothermal cooling of the heat transfer fluid in the geothermal heat exchanger portion. Based on an appropriate metric, a determination is made that a switch should be made from the first mode to a second, different, mode; and, responsive thereto, the data center cooling system is switched to the second mode. The second mode includes at least another of ambient air cooling of the heat transfer fluid in the outdoor heat exchanger portion and geothermal cooling of the heat transfer fluid in the geothermal heat exchanger portion. |
| FILED | Saturday, July 11, 2020 |
| APPL NO | 16/926663 |
| ART UNIT | 3763 — Refrigeration, Vaporization, Ventilation, and Combustion |
| CURRENT CPC | Electric Digital Data Processing G06F 1/20 (20130101) G06F 2200/201 (20130101) Printed Circuits; Casings or Constructional Details of Electric Apparatus; Manufacture of Assemblages of Electrical Components H05K 7/2079 (20130101) H05K 7/20654 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Aeronautics and Space Administration (NASA)
| US 11236764 | Phui et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aerojet Rocketdyne, Inc. (Sacramento, California) |
| ASSIGNEE(S) | Aerojet Rocketdyne, Inc. (Canoga Park, California) |
| INVENTOR(S) | Khin Phui (Cucamonga, California); Sen Meng (Reseda, California) |
| ABSTRACT | A pump includes an axial inducer. The axial inducer includes a housing that has an internal surface that defines an axial fluid passage. A rotor is disposed about a central axis in the fluid passage. The rotor includes at least one blade that defines at least one blade tip. The internal surface of the housing defines a plurality of grooves adjacent the at least one blade tip. The grooves are elongated in a circumferential direction. |
| FILED | Friday, October 12, 2018 |
| APPL NO | 16/767820 |
| ART UNIT | 3746 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Non-positive-displacement Pumps F04D 29/52 (20130101) Original (OR) Class F04D 29/688 (20130101) F04D 29/4293 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2250/50 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237056 | Hosseini |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | California Institute of Technology (Pasadena, California) |
| ASSIGNEE(S) | California Institute of Technology (Pasadena, California) |
| INVENTOR(S) | Seyedeh Sona Hosseini (Pasadena, California) |
| ABSTRACT | Novel monolithic cyclical reflective spatial heterodyne spectrometers (CRSHS) are presented. Monolithic CRSHS in accordance with the invention have a single frame wherein a flat mirror, roof mirror, and symmetric grating are affixed. The invention contains only fixed parts; the flat mirror, roof mirror, and symmetric grating do not move in relation to the frame. Compared to conventional CRSHS known in the art, the present invention enables much smaller and lighter CRSHS, requires less time and skill for maintenance, and is a better economic option. The disclosed invention may include fixed field-widening optical elements or a fiber-fed assembly. |
| FILED | Tuesday, November 07, 2017 |
| APPL NO | 15/806305 |
| ART UNIT | 2886 — Optics |
| CURRENT CPC | Measurement of Intensity, Velocity, Spectral Content, Polarisation, Phase or Pulse Characteristics of Infra-Red, Visible or Ultra-violet Light; Colorimetry; Radiation Pyrometry G01J 3/18 (20130101) G01J 3/0202 (20130101) G01J 3/0205 (20130101) G01J 3/0218 (20130101) G01J 3/0259 (20130101) G01J 3/453 (20130101) Original (OR) Class G01J 3/1804 (20130101) G01J 3/4531 (20130101) G01J 3/4532 (20130101) G01J 2003/1204 (20130101) G01J 2003/1208 (20130101) G01J 2003/1861 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238196 | Bolander et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Sentient Science Corporation (Buffalo, New York) |
| ASSIGNEE(S) | Sentient Science Corporation (Buffalo, New York) |
| INVENTOR(S) | Nathan Bolander (Idaho Falls, Idaho); Rajasekhar V. Pulikollu (Nashville, Tennessee); Behrooz Jalalahmadi (Idaho Falls, Idaho) |
| ABSTRACT | A system and method for determining surface contact fatigue life may use a finite element method to determine when components, such as a power transmission component, may fail in operation. The method may generate a finite element model based on the material parameters related to a power transmission component, generate a surface pressure time history for a loading event based on one or more loading parameters, determine, based on the surface pressure time history for a loading event, a finite element solution that describes stress in the grain structure, calculate damage in the finite element solution using a damage model, and determine whether a damage threshold is exceeded. |
| FILED | Tuesday, November 12, 2019 |
| APPL NO | 16/680728 |
| ART UNIT | 2863 — Printing/Measuring and Testing |
| CURRENT CPC | Gearing F16H 2057/0087 (20130101) Testing Static or Dynamic Balance of Machines or Structures; Testing of Structures or Apparatus, Not Otherwise Provided for G01M 13/022 (20130101) Electric Digital Data Processing G06F 17/18 (20130101) G06F 30/23 (20200101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239567 | Freebury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TENDEG LLC (Louisville, Colorado) |
| ASSIGNEE(S) | TENDEG LLC (Louisville, Colorado) |
| INVENTOR(S) | Gregg E. Freebury (Louisville, Colorado); Matthew Phillip Mitchell (Colorado Springs, Colorado) |
| ABSTRACT | An antenna having a reflector mounted on a rigid boom uses a line feed or phased array feed to operate in the Ka band with frequencies up to 36 gigahertz while maintaining the ability to operate at frequencies down to L-Band of 1-2 GHz. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 16/869420 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 15/14 (20130101) Original (OR) Class H01Q 15/141 (20130101) H01Q 15/147 (20130101) H01Q 15/161 (20130101) H01Q 15/162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239745 | Hesterman |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Aerojet Rocketdyne, Inc. (Sacramento, California) |
| ASSIGNEE(S) | AEROJET ROCKETDYNE, INC (Redmond, Washington) |
| INVENTOR(S) | Bryce L. Hesterman (Redmond, Washington) |
| ABSTRACT | A power converter includes a first rectifier circuit having a pair of first rectifier circuit output terminals and a second rectifier circuit having a pair of second rectifier circuit output terminals, a snubber circuit comprising a first diode and a first capacitor connected to each other at a first node and connecting the pair of first rectifier circuit output terminals, a second diode and a second capacitor connected to each other at a second node and connecting the pair of second rectifier circuit output terminals, a third diode connecting the first node to one of the pair of second rectifier output terminals, and a fourth diode connecting the second node to one of the pair of first rectifier output terminals. |
| FILED | Wednesday, April 11, 2018 |
| APPL NO | 17/045607 |
| ART UNIT | 2838 — Electrical Circuits and Systems |
| CURRENT CPC | Apparatus for Conversion Between AC and AC, Between AC and DC, or Between DC and DC, and for Use With Mains or Similar Power Supply Systems; Conversion of DC or AC Input Power into Surge Output Power; Control or Regulation Thereof H02M 1/34 (20130101) Original (OR) Class H02M 1/0048 (20210501) H02M 1/0077 (20210501) H02M 1/346 (20210501) H02M 7/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Small Business Administration (SBA)
| US 11235141 | Lucke et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Minnetronix, Inc. (St. Paul, Minnesota) |
| ASSIGNEE(S) | Minnetronix, Inc. (St. Paul, Minnesota) |
| INVENTOR(S) | Lori Lucke (Rosemount, Minnesota); Vlad Bluvshtein (Plymouth, Minnesota); James Kurkowski (Roseville, Minnesota); William Weiss (Mechanicsburg, Pennsylvania) |
| ABSTRACT | Disclosed are systems and methods for use of an inductive link for a communication channel in a transcutaneous energy transfer system. An example system may include a resonant circuit associated with an external primary, a power transistor connected to the resonant circuit and configured to drive the resonant circuit with a first time-varying electrical signal having a frequency, and a power driver connected to the power transistor that is configured to set the frequency of the first time-varying electrical signal to a resonant frequency to enable power transfer from the external primary to an implanted secondary. The example system may further include a communication driver operatively connected to the power transistor and configured to encode the first time-varying electrical signal with a data signal by modulating an attribute of the time-varying electrical signal as electrical power is transferred from the external primary to the implanted secondary. |
| FILED | Monday, September 09, 2019 |
| APPL NO | 16/564210 |
| ART UNIT | 3792 — Medical Instruments, Diagnostic Equipment, and Treatment Devices |
| CURRENT CPC | Devices for Introducing Media Into, or Onto, the Body; Devices for Transducing Body Media or for Taking Media From the Body; Devices for Producing or Ending Sleep or Stupor A61M 60/148 (20210101) A61M 60/205 (20210101) A61M 60/871 (20210101) Original (OR) Class Electrotherapy; Magnetotherapy; Radiation Therapy; Ultrasound Therapy A61N 1/3727 (20130101) A61N 1/3787 (20130101) A61N 1/37223 (20130101) Transmission H04B 3/54 (20130101) H04B 3/548 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11235361 | Quigley et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| ASSIGNEE(S) | Loci Controls, Inc. (Wareham, Massachusetts) |
| INVENTOR(S) | Peter Quigley (Duxbury, Massachusetts); Ian Martin (Sharon, Massachusetts); Nicole Neff (Colorado Springs, Colorado); Jack Rowbottom (Swansea, Massachusetts) |
| ABSTRACT | Described herein are embodiments of a control system that automatically (1) determines whether a gas extraction system is in a state in which landfill gas is being released into the atmosphere, and (2) automatically controls landfill gas flow to mitigate, prevent and/or stop the release of landfill gas. The control system may control a valve to control flow of landfill gas through well piping of the gas extraction system. The pressure of landfill gas in the well piping at a location upstream of the valve may indicate whether there is a risk of landfill gas being released into the atmosphere. The control system may adjust a position of the valve in response to determining that the pressure at the location upstream of the valve indicates that there is a risk of landfill gas being released into the atmosphere. |
| FILED | Monday, November 02, 2020 |
| APPL NO | 17/086987 |
| ART UNIT | 3672 — Wells, Earth Boring/Moving/Working, Excavating, Mining, Harvesters, Bridges, Roads, Petroleum, Closures, Connections, and Hardware |
| CURRENT CPC | Disposal of Solid Waste B09B 1/006 (20130101) Original (OR) Class Earth Drilling, e.g Deep Drilling; Obtaining Oil, Gas, Water, Soluble or Meltable Materials or a Slurry of Minerals From Wells E21B 34/02 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/30 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237369 | Weida et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | DAYLIGHT SOLUTIONS, INC. (San Diego, California) |
| ASSIGNEE(S) | DAYLIGHT SOLUTIONS, INC. (San Diego, California) |
| INVENTOR(S) | Miles James Weida (Poway, California); Timothy Day (Poway, California) |
| ABSTRACT | An imaging microscope (12) for generating an image of a sample (10) comprises a beam source (14) that emits a temporally coherent illumination beam (20), the illumination beam (20) including a plurality of rays that are directed at the sample (10); an image sensor (18) that converts an optical image into an array of electronic signals; and an imaging lens assembly (16) that receives rays from the beam source (14) that are transmitted through the sample (10) and forms an image on the image sensor (18). The imaging lens assembly (16) can further receive rays from the beam source (14) that are reflected off of the sample (10) and form a second image on the image sensor (18). The imaging lens assembly (16) receives the rays from the sample (10) and forms the image on the image sensor (18) without splitting and recombining the rays. |
| FILED | Friday, March 20, 2020 |
| APPL NO | 16/825916 |
| ART UNIT | 2487 — Recording and Compression |
| CURRENT CPC | Optical Elements, Systems, or Apparatus G02B 21/00 (20130101) G02B 21/0056 (20130101) Original (OR) Class G02B 21/0088 (20130101) G02B 21/088 (20130101) G02B 21/365 (20130101) Pictorial Communication, e.g Television H04N 5/33 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239567 | Freebury et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | TENDEG LLC (Louisville, Colorado) |
| ASSIGNEE(S) | TENDEG LLC (Louisville, Colorado) |
| INVENTOR(S) | Gregg E. Freebury (Louisville, Colorado); Matthew Phillip Mitchell (Colorado Springs, Colorado) |
| ABSTRACT | An antenna having a reflector mounted on a rigid boom uses a line feed or phased array feed to operate in the Ka band with frequencies up to 36 gigahertz while maintaining the ability to operate at frequencies down to L-Band of 1-2 GHz. |
| FILED | Thursday, May 07, 2020 |
| APPL NO | 16/869420 |
| ART UNIT | 2844 — Electrical Circuits and Systems |
| CURRENT CPC | Antennas, i.e Radio Aerials H01Q 15/14 (20130101) Original (OR) Class H01Q 15/141 (20130101) H01Q 15/147 (20130101) H01Q 15/161 (20130101) H01Q 15/162 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Agriculture (USDA)
| US 11236315 | Donovan et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The United States of America, as Represented by the Secretary of Agriculture (Washington, District of Columbia); University of Maryland (College Park, Maryland) |
| ASSIGNEE(S) | The United States of America, as represented by the Secretary of Agriculture (Washington, District of Columbia); University of Maryland (College Park, Maryland) |
| INVENTOR(S) | David M. Donovan (Essex, Maryland); Steven M. Swift (Bethesda, Maryland) |
| ABSTRACT | The disclosure relates to chimeric recombinant lysins comprising at least one thermophile endolysin catalytic domain and at least one cell wall binding domain. Also disclosed are polynucleotides encoding the chimeric recombinant lysins, host cells expressing the chimeric recombinant lysins, and use of such chimeric recombinant lysins. |
| FILED | Thursday, April 04, 2019 |
| APPL NO | 16/375287 |
| ART UNIT | 1656 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Fodder A23K 20/147 (20160501) Preparations for Medical, Dental, or Toilet Purposes A61K 38/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 31/04 (20180101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/2462 (20130101) Original (OR) Class Enzymes C12Y 302/01017 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236355 | Staskawicz et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California) |
| INVENTOR(S) | Brian J. Staskawicz (Berkeley, California); Alexander Christiaan Schultink (Berkeley, California) |
| ABSTRACT | Provided herein is a non-Nicotiana transgenic plant comprising an exogenous polynucleotide encoding Nicotiana benthamiana Roq1 or a variant thereof. These plants have enhanced resistance to at least one species of Xanthomonas, Pseudomonas, Ralstonia, and/or another pathogen containing a homolog of XopQ whose recognition is mediated by Roq1. |
| FILED | Tuesday, August 21, 2018 |
| APPL NO | 16/639379 |
| ART UNIT | 1662 — Plants |
| CURRENT CPC | Peptides C07K 14/415 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/8281 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236368 | Steele et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| ASSIGNEE(S) | Wisconsin Alumni Research Foundation (Madison, Wisconsin) |
| INVENTOR(S) | James L. Steele (Madison, Wisconsin); Jeffrey Broadbent (Logan, Utah); Ekkarat Phrommao (Madison, Wisconsin) |
| ABSTRACT | An ethanologen for producing biofuel from one or more carbohydrates and reducing lactate and acetate production in a biofuel manufacturing process. The ethanologen is made by introducing into the ethanologen one or more exogenous genes required for production of a bacteriocin. The resulting ethanologen reduces lactate and acetate production by contaminant lactic acid bacteria by expression of the bacteriocin during the biofuel manufacturing process. Certain resulting ethanologens ferment sugars not naturally or not preferentially utilized by Saccharomyces cerevisiae during the manufacturing process. |
| FILED | Thursday, July 13, 2017 |
| APPL NO | 15/648872 |
| ART UNIT | 1652 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Peptides C07K 14/195 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 1/16 (20130101) C12N 1/20 (20130101) C12N 1/38 (20130101) C12N 9/88 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/06 (20130101) C12P 7/10 (20130101) C12P 7/065 (20130101) Original (OR) Class C12P 7/649 (20130101) C12P 21/02 (20130101) Enzymes C12Y 101/01001 (20130101) C12Y 401/01001 (20130101) Reduction of Greenhouse Gas [GHG] Emissions, Related to Energy Generation, Transmission or Distribution Y02E 50/10 (20130101) Y02E 50/30 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Homeland Security (DHS)
| US 11235181 | Daeffler et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Michael Daeffler (Salem, Connecticut); Michael Plumley (New London, Connecticut); Ronald Adrezin (East Lyme, Connecticut) |
| ABSTRACT | In an example, a respirator includes a respirator body having a distal portion and a proximal portion, the distal portion including a filter housing wall and an open distal end. The proximal portion includes a facial interface which is compliant and deformable from an undeformed state to a deformed state to conform to a facial contour of an individual. One or more filter frames are inserted into the distal portion and supported by the filter housing wall to separate filter media on opposite sides of at least one of the one or more filter frames. A filter cover is releasably attached to the open distal end to enclose the one or more filter frames and filter media, forming a filter housing. The one or more filter frames are removable from the distal portion and replaced into the distal portion to allow replacement of the filter media. |
| FILED | Thursday, November 12, 2020 |
| APPL NO | 17/096561 |
| ART UNIT | 3785 — Body Treatment, Kinestherapy, and Exercising |
| CURRENT CPC | Devices, Apparatus or Methods for Life-saving A62B 7/10 (20130101) Original (OR) Class A62B 9/06 (20130101) A62B 18/025 (20130101) A62B 18/084 (20130101) A62B 23/02 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237083 | Cho |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| ASSIGNEE(S) | The Government of the United States of America, as represented by the Secretary of Homeland Security (Washington, District of Columbia) |
| INVENTOR(S) | Inho Cho (Egg Harbor Township, New Jersey) |
| ABSTRACT | In an example, a thermal extraction apparatus includes: a housing having a gas inlet and a gas outlet to receive a gas flow through the housing from the gas inlet to the gas outlet, and a side opening to receive a sample collector, having a sample collector adsorbent containing a vapor sample, into a sample collector location; a pump to generate the gas flow; a heater to heat the sample collector adsorbent of the sample collector to a temperature sufficient to release the vapor sample; a thermal desorption (TD) tube connected with the gas outlet of the housing to receive the gas flow downstream of the sample collector and collect the vapor sample released from the sample collector adsorbent of the sample collector; and a cooling member in heat exchange with the TD tube to cool the TD tube. |
| FILED | Friday, January 29, 2021 |
| APPL NO | 17/162984 |
| ART UNIT | 2856 — Printing/Measuring and Testing |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 1/44 (20130101) G01N 1/2214 (20130101) Original (OR) Class G01N 1/2247 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237143 | Gregory et al. |
|---|---|
| FUNDED BY |
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| APPLICANT(S) | Massachusetts Institute Of Technology (Cambridge, Massachusetts) |
| ASSIGNEE(S) | Massachusetts Institute Of Technology (Cambridge, Massachusetts) |
| INVENTOR(S) | Kerin E. Gregory (Bolton, Massachusetts); Roderick R. Kunz (Acton, Massachusetts); Michael Sworin (Marlboro, Massachusetts) |
| ABSTRACT | Reagents and methods are disclosed for detection of oxidizers and inorganic salts and other analytes of interest. The reagents can interact with their target analytes, especially oxidizer compositions or oxidizer-based explosives, to selectively enhance their ionization yield, interacting by chemical reaction or by forming an associative adduct which facilitates their detection. For example, the reagents can adduct with the counter-ion of the intended analyte for improved direct detection and/or react chemically via acid-base reactions to produce a new product for detection. In another aspect of the invention, reactive reagents and methods are also disclosed that facilitate indirect detection of the analyte at lower temperatures based on reduction-oxidation (redox) chemistry. These reagents are particularly useful in detecting oxidizer analytes. |
| FILED | Friday, February 17, 2017 |
| APPL NO | 15/435733 |
| ART UNIT | 1797 — Food, Analytical Chemistry, Sterilization, Biochemistry, Electrochemistry |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 27/622 (20130101) G01N 31/227 (20130101) G01N 33/227 (20130101) Original (OR) Class G01N 2001/028 (20130101) Technical Subjects Covered by Former US Classification Y10T 436/19 (20150115) Y10T 436/24 (20150115) Y10T 436/141111 (20150115) Y10T 436/143333 (20150115) Y10T 436/173076 (20150115) Y10T 436/206664 (20150115) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Veterans Affairs (DVA)
| US 11236139 | Dubinett et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | The Regents of the University of California (Oakland, California); United States Government represented by the Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (Oakland, California); UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Steven M. Dubinett (Los Angeles, California); Sherven Sharma (Culver City, California); Jay M. Lee (Los Angeles, California) |
| ABSTRACT | The invention is based on the disclosure provided herein that secondary lymphoid organ chemokine (SLC) inhibits the growth of syngeneic tumors in vivo. Thus, the invention provides a method of treating cancer in a mammal subject by administering a therapeutically effective amount of an SLC to the mammal in combination with a checkpoint inhibitor, including monoclonal antibodies and small molecule inhibitors. Exemplary checkpoint molecules include CTLA-4, a CTLA-4 receptor, PD-1, PD1-L1, PD1-L2, 4-1BB, OX40, LAG-3, TIM-3 or a combination thereof. SLCs useful in the methods of the invention include SLC polypeptides, variants and fragments and related nucleic acids. |
| FILED | Thursday, November 05, 2015 |
| APPL NO | 15/524740 |
| ART UNIT | 1643 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 9/0019 (20130101) A61K 38/195 (20130101) A61K 38/195 (20130101) A61K 39/0011 (20130101) A61K 39/3955 (20130101) A61K 39/3955 (20130101) A61K 39/39558 (20130101) A61K 45/06 (20130101) A61K 48/00 (20130101) A61K 2039/54 (20130101) A61K 2039/545 (20130101) A61K 2039/5154 (20130101) A61K 2039/5256 (20130101) A61K 2300/00 (20130101) A61K 2300/00 (20130101) Specific Therapeutic Activity of Chemical Compounds or Medicinal Preparations A61P 35/00 (20180101) Peptides C07K 14/521 (20130101) Original (OR) Class C07K 16/24 (20130101) C07K 16/249 (20130101) C07K 16/2818 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 7/00 (20130101) C12N 2710/10041 (20130101) C12N 2710/10043 (20130101) C12N 2710/10071 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236340 | Wyss-Coray et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| ASSIGNEE(S) | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (Stanford, California); THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (Washington, District of Columbia) |
| INVENTOR(S) | Anton Wyss-Coray (Palo Alto, California); Thomas A. Rando (Stanford, California); Markus Britschgi (Allscwil, Switzerland); Kaspar Rufibach (Basel, Switzerland); Saul A. Villeda (Lancaster, California) |
| ABSTRACT | Methods of treating an adult mammal for an aging-associated impairment are provided. Aspects of the methods include modulating CCR3, e.g., by modulating eotaxin-1/CCR3 interaction, in the mammal in a manner sufficient to treat the mammal for the aging-associated impairment. A variety of aging-associated impairments may be treated by practice of the methods, which impairments include cognitive impairments. |
| FILED | Tuesday, April 07, 2020 |
| APPL NO | 16/842054 |
| ART UNIT | 1647 — Immunology, Receptor/Ligands, Cytokines Recombinant Hormones, and Molecular Biology |
| CURRENT CPC | Preparations for Medical, Dental, or Toilet Purposes A61K 31/00 (20130101) A61K 31/7088 (20130101) A61K 38/19 (20130101) A61K 38/45 (20130101) A61K 2039/505 (20130101) Peptides C07K 16/24 (20130101) C07K 16/28 (20130101) C07K 2317/76 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 15/1138 (20130101) Original (OR) Class C12N 2310/14 (20130101) C12N 2799/06 (20130101) C12N 2799/022 (20130101) Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6883 (20130101) C12Q 2600/136 (20130101) C12Q 2600/158 (20130101) Enzymes C12Y 207/10001 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236398 | Glazko et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BioVentures, LLC (Little Rock, Arkansas); The United States As Represented By The Department of Veterans Affairs (Washington, District of Columbia) |
| ASSIGNEE(S) | BioVentures, LLC (Little Rock, Arkansas); The United States As Represented By The Department of Veterans Affairs (Washington, District of Columbia) |
| INVENTOR(S) | Galina Glazko (Little Rock, Arkansas); Curt H. Hagedorn (Little Rock, Arkansas); Yasir Rahmatallah (Little Rock, Arkansas) |
| ABSTRACT | The disclosure provides a method to detect sessile serrated adenomas/polyps (SSA/Ps) and to differentiate SSA/Ps from hyperplastic polyps (HPs). The method uses a molecular signature that is platform-independent and could be used with multiple platforms such as microarray, RNA-seq or real-time quantitative platforms. |
| FILED | Thursday, March 01, 2018 |
| APPL NO | 16/489604 |
| ART UNIT | 1634 — Molecular Biology, Bioinformatics, Nucleic Acids, Recombinant DNA and RNA, Gene Regulation, Nucleic Acid Amplification, Animals and Plants, Combinatorial/ Computational Chemistry |
| CURRENT CPC | Measuring or Testing Processes Involving Enzymes, Nucleic Acids or Microorganisms; Compositions or Test Papers Therefor; Processes of Preparing Such Compositions; Condition-responsive Control in Microbiological or Enzymological Processes C12Q 1/6886 (20130101) Original (OR) Class C12Q 2600/112 (20130101) C12Q 2600/118 (20130101) Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 2800/7028 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
United States Postal Service (USPS)
| US 11235903 | Lee, Sr. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | James Edward Lee, Sr. (St. Leonard, Maryland) |
| ABSTRACT | Embodiments of a reusable stackable shipping box are provided herein. The reusable stackable shipping box may be reused and cleaned without causing harm to the integrity of the box. In addition, the box is slightly tapered in shape such that the box may be stacked upon and within other boxes for ease in shipping and organization. |
| FILED | Wednesday, April 22, 2020 |
| APPL NO | 16/855392 |
| ART UNIT | 3734 — Sheet Container Making, Package Making, Receptacles, Shoes, Apparel, and Tool Driving or Impacting |
| CURRENT CPC | Containers for Storage or Transport of Articles or Materials, e.g Bags, Barrels, Bottles, Boxes, Cans, Cartons, Crates, Drums, Jars, Tanks, Hoppers, Forwarding Containers; Accessories, Closures, or Fittings Therefor; Packaging Elements; Packages B65D 5/001 (20130101) Original (OR) Class B65D 5/10 (20130101) B65D 5/14 (20130101) B65D 5/0245 (20130101) B65D 5/0281 (20130101) B65D 5/4266 (20130101) B65D 5/4608 (20130101) B65D 5/48024 (20130101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 30/80 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238298 | Schimmel |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Todd M. Schimmel (Annandale, Virginia) |
| ABSTRACT | Systems, devices, and methods for monitoring items in a defined physical area can include a primary camera configured to detect a region of interest within a defined physical area and the coordinates of the region of interest in the defined physical area. A plurality of secondary cameras can positioned throughout a defined physical area. One of the secondary cameras can be selected to capture an image of a region of interest based on the coordinates of the region of interest. |
| FILED | Tuesday, March 17, 2020 |
| APPL NO | 16/821714 |
| ART UNIT | 2665 — Image Analysis; Applications; Pattern Recognition; Color and compression; Enhancement and Transformation |
| CURRENT CPC | Recognition of Data; Presentation of Data; Record Carriers; Handling Record Carriers G06K 9/00744 (20130101) G06K 9/00771 (20130101) G06K 9/3233 (20130101) Original (OR) Class Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/087 (20130101) G06Q 10/0833 (20130101) Image Data Processing or Generation, in General G06T 7/11 (20170101) Pictorial Communication, e.g Television H04N 5/23203 (20130101) H04N 5/23238 (20130101) H04N 7/181 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11238399 | Dixon et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | United States Postal Service (Washington, District of Columbia) |
| ASSIGNEE(S) | United States Postal Service (Washington, District of Columbia) |
| INVENTOR(S) | Robert E. Dixon (Haymarket, Virginia); Ryan Luckay (Vienna, Virginia) |
| ABSTRACT | Methods and systems for on demand logistics management are disclosed. An on-demand logistics system includes an electronic hardware processor configured to receive an on-demand request, the request indicating an on-demand location for an on-demand transaction, determine locations of a plurality of vehicles on a plurality of delivery routes, determine whether the on-demand location is within a threshold distance of at least one of the plurality of delivery routes based on the vehicle locations and assign the on-demand transaction to a vehicle based on the determination. |
| FILED | Monday, July 16, 2018 |
| APPL NO | 16/036829 |
| ART UNIT | 3662 — Computerized Vehicle Controls and Navigation, Radio Wave, Optical and Acoustic Wave Communication, Robotics, and Nuclear Systems |
| CURRENT CPC | Measuring Distances, Levels or Bearings; Surveying; Navigation; Gyroscopic Instruments; Photogrammetry or Videogrammetry G01C 21/343 (20130101) G01C 21/3415 (20130101) Systems for Controlling or Regulating Non-electric Variables G05D 1/0212 (20130101) G05D 1/0287 (20130101) G05D 2201/0212 (20130101) G05D 2201/0213 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/0834 (20130101) G06Q 10/06315 (20130101) G06Q 10/08355 (20130101) Original (OR) Class |
| VIEW PATENT | @ USPTO: Full Text PDF |
Department of Transportation (USDOT)
| US 11235307 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Ni-Bin Chang (Orlando, Florida); Martin P. Wanielista (Orlando, Florida) |
| ABSTRACT | A synergistic composition can be used to treat water containing nitrogen compounds and phosphorus compounds. The synergistic composition includes iron filings, clay particles, aluminum particles, and sand particles. The iron filings, clay particles, and aluminum particles act synergistically to remove nitrogen compounds and phosphorus compounds from water. Specifically, the clay particles attract the nitrogen compounds and the phosphorus compounds to be absorbed onto a surface of the iron filings and the clay particles. The aluminum particles react with the nitrogen compounds via an oxidation reaction to form ammonia compounds, and react with the phosphorus compounds to produce aluminum phosphate. As such, the synergistic relationship between the iron filings, clay particles, and aluminum particles remove nitrogen and phosphorus compounds from water and recover the compounds in usable forms, namely, ammonia and aluminum phosphate. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/302895 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/12 (20130101) B01J 20/103 (20130101) B01J 20/0229 (20130101) B01J 20/0248 (20130101) B01J 20/261 (20130101) B01J 20/28016 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/72 (20130101) C02F 1/281 (20130101) C02F 1/285 (20130101) C02F 1/288 (20130101) C02F 1/705 (20130101) C02F 1/5245 (20130101) C02F 2101/16 (20130101) C02F 2101/105 (20130101) C02F 2101/163 (20130101) C02F 2103/001 (20130101) C02F 2103/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236322 | Corgie et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| ASSIGNEE(S) | CORNELL UNIVERSITY (Ithaca, New York) |
| INVENTOR(S) | Stephane C. Corgie (Ithaca, New York); Xiaonan Duan (Ithaca, New York); Emmanuel Giannelis (Ithaca, New York); Daniel Aneshansley (Ithaca, New York); Larry P. Walker (Ithaca, New York) |
| ABSTRACT | A hierarchical catalyst composition comprising a continuous or particulate macroporous scaffold in which is incorporated mesoporous aggregates of magnetic nanoparticles, wherein an enzyme is embedded in mesopores of the mesoporous aggregates of magnetic nanoparticles. Methods for synthesizing the hierarchical catalyst composition are also described. Also described are processes that use the recoverable hierarchical catalyst composition for depolymerizing lignin, remediation of water contaminated with aromatic substances, polymerizing monomers by a free-radical mechanism, epoxidation of alkenes, halogenation of phenols, inhibiting growth and function of microorganisms in a solution, and carbon dioxide conversion to methanol. Further described are methods for increasing the space time yield and/or total turnover number of a liquid-phase chemical reaction that includes magnetic particles to facilitate the chemical reaction, the method comprising subjecting the chemical reaction to a plurality of magnetic fields of selected magnetic strength, relative position in the chemical reaction, and relative motion. |
| FILED | Friday, August 28, 2020 |
| APPL NO | 17/005962 |
| ART UNIT | 1655 — Fermentation, Microbiology, Isolated and Recombinant Proteins/Enzymes |
| CURRENT CPC | Chemical Means for Extinguishing Fires or for Combating or Protecting Against Harmful Chemical Agents; Chemical Materials for Use in Breathing Apparatus A62D 3/02 (20130101) Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 8/00 (20130101) B01J 19/12 (20130101) B01J 31/02 (20130101) B01J 31/003 (20130101) B01J 35/04 (20130101) B01J 35/0033 (20130101) B01J 35/1061 (20130101) B01J 35/1066 (20130101) B01J 37/02 (20130101) B01J 2208/00805 (20130101) B01J 2219/0854 (20130101) B01J 2219/0862 (20130101) Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/484 (20130101) C02F 3/00 (20130101) C02F 3/342 (20130101) C02F 2101/327 (20130101) C02F 2209/006 (20130101) C02F 2303/04 (20130101) C02F 2305/08 (20130101) Acyclic or Carbocyclic Compounds C07C 1/12 (20130101) Heterocyclic Compounds C07D 301/22 (20130101) Compounds of Unknown Constitution C07G 1/00 (20130101) Macromolecular Compounds Obtained by Reactions Only Involving Carbon-to-carbon Unsaturated Bonds C08F 14/00 (20130101) C08F 18/00 (20130101) Microorganisms or Enzymes; Compositions Thereof; Propagating, Preserving, or Maintaining Microorganisms; Mutation or Genetic Engineering; Culture Media C12N 9/0004 (20130101) C12N 9/0006 (20130101) C12N 9/0061 (20130101) C12N 9/0065 (20130101) C12N 11/04 (20130101) Original (OR) Class C12N 11/08 (20130101) C12N 11/14 (20130101) C12N 13/00 (20130101) Fermentation or Enzyme-using Processes to Synthesise a Desired Chemical Compound or Composition or to Separate Optical Isomers From a Racemic Mixture C12P 7/04 (20130101) C12P 7/22 (20130101) C12P 17/02 (20130101) Enzymes C12Y 101/03004 (20130101) C12Y 111/01 (20130101) Climate Change Mitigation Technologies in the Production or Processing of Goods Y02P 20/50 (20151101) Climate Change Mitigation Technologies Related to Wastewater Treatment or Waste Management Y02W 10/40 (20150501) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Office of the Director of National Intelligence (ODNI)
| US 11238470 | Stepp et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | HRL Laboratories, LLC (Malibu, California) |
| ASSIGNEE(S) | HRL Laboratories, LLC (Malibu, California) |
| INVENTOR(S) | Nigel D. Stepp (Santa Monica, California); David J. Huber (Calabasas, California); Tsai-Ching Lu (Thousand Oaks, California) |
| ABSTRACT | A method for collecting and processing user input. In some embodiments the method includes presenting a first user with a prompt for eliciting a first response, the first response including a numerical portion including one or more numbers, and an explanatory portion; receiving, from the first user, the first response; receiving from each of a plurality of other users, a respective response of a plurality of other responses; and displaying, to the first user, an ordered list of other responses. Within the ordered list, a second response, of the plurality of other responses, may be earlier than a third response, of the plurality of other responses, the second response being, according to a measure of distance, more distant, than the third response, from the first response. |
| FILED | Friday, December 20, 2019 |
| APPL NO | 16/724130 |
| ART UNIT | 3623 — Business Methods - Incentive Programs, Coupons; Operations Research; Electronic Shopping; Health Care; Point of Sale, Inventory, Accounting; Cost/ Price, Reservations, Shipping and Transportation; Business Processing |
| CURRENT CPC | Electric Digital Data Processing G06F 17/16 (20130101) Data Processing Systems or Methods, Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes; Systems or Methods Specially Adapted for Administrative, Commercial, Financial, Managerial, Supervisory or Forecasting Purposes, Not Otherwise Provided for G06Q 10/04 (20130101) G06Q 30/0203 (20130101) Original (OR) Class G06Q 30/0204 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11239996 | Masters et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Oliver Paul Masters (Birmingham, United Kingdom); Hamish C Hunt (Ashford, United Kingdom); Flavio A Bergamaschi (Southampton, United Kingdom); Enrico Steffinlongo (Winchester, United Kingdom) |
| ABSTRACT | Various embodiments are provided for performing weighted partial matching under homomorphic encryption in a computing environment. Selected data may be encoded and encrypted into an encrypted query for comparison using private set intersection (PSI) under homomorphic encryption (HE). An encrypted score may be determined according to data blocks of the selected data and a set of weights for each of the data blocks of the selected data to identify matches between the data and the encrypted query. The encrypted score may be decrypted and decoded to identify matches between the encrypted query with the selected data. |
| FILED | Wednesday, December 18, 2019 |
| APPL NO | 16/719056 |
| ART UNIT | 2491 — Cryptography and Security |
| CURRENT CPC | Electric Digital Data Processing G06F 16/245 (20190101) G06F 21/602 (20130101) Transmission of Digital Information, e.g Telegraphic Communication H04L 9/008 (20130101) Original (OR) Class H04L 9/3073 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
National Security Agency (NSA)
| US 11237933 | Riabov et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | International Business Machines Corporation (Armonk, New York) |
| ASSIGNEE(S) | INTERNATIONAL BUSINESS MACHINES CORPORATION (Armonk, New York) |
| INVENTOR(S) | Anton V. Riabov (Ann Arbor, Michigan); Shirin Sohrabi Araghi (Port Chester, New York); Octavian Udrea (Ossining, New York) |
| ABSTRACT | Techniques for solving a multi-agent plan recognition problem are provided. In one example, a computer-implemented method comprises transforming, by a device operatively coupled to a processor, a problem model and an at least partially ordered sequence of observations into an artificial intelligence planning problem through a transform algorithm. The problem model can comprises a domain description from a plurality of agents and a durative action. Furthermore, at least one of the observations of the at least partially ordered sequence of observations can be a condition that changes over time. The computer-implemented method further comprises determining, by the device, plan information using an artificial intelligence planner on the artificial intelligence planning problem. The computer-implemented method further comprises translating, by the device, the plan information into information indicative of a solution to the artificial intelligence planning problem. |
| FILED | Thursday, December 14, 2017 |
| APPL NO | 15/842449 |
| ART UNIT | 2488 — Recording and Compression |
| CURRENT CPC | Electric Digital Data Processing G06F 9/4862 (20130101) G06F 11/302 (20130101) Original (OR) Class G06F 11/3006 (20130101) G06F 11/3438 (20130101) G06F 16/951 (20190101) Computer Systems Based on Specific Computational Models G06N 5/043 (20130101) G06N 20/00 (20190101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
U.S. State Government
| US 11235307 | Chang et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| ASSIGNEE(S) | University of Central Florida Research Foundation, Inc. (Orlando, Florida) |
| INVENTOR(S) | Ni-Bin Chang (Orlando, Florida); Martin P. Wanielista (Orlando, Florida) |
| ABSTRACT | A synergistic composition can be used to treat water containing nitrogen compounds and phosphorus compounds. The synergistic composition includes iron filings, clay particles, aluminum particles, and sand particles. The iron filings, clay particles, and aluminum particles act synergistically to remove nitrogen compounds and phosphorus compounds from water. Specifically, the clay particles attract the nitrogen compounds and the phosphorus compounds to be absorbed onto a surface of the iron filings and the clay particles. The aluminum particles react with the nitrogen compounds via an oxidation reaction to form ammonia compounds, and react with the phosphorus compounds to produce aluminum phosphate. As such, the synergistic relationship between the iron filings, clay particles, and aluminum particles remove nitrogen and phosphorus compounds from water and recover the compounds in usable forms, namely, ammonia and aluminum phosphate. |
| FILED | Friday, May 14, 2021 |
| APPL NO | 17/302895 |
| ART UNIT | 1773 — Chemical Apparatus, Separation and Purification, Liquid and Gas Contact Apparatus |
| CURRENT CPC | Chemical or Physical Processes, e.g Catalysis or Colloid Chemistry; Their Relevant Apparatus B01J 20/12 (20130101) B01J 20/103 (20130101) B01J 20/0229 (20130101) B01J 20/0248 (20130101) B01J 20/261 (20130101) B01J 20/28016 (20130101) Original (OR) Class Treatment of Water, Waste Water, Sewage, or Sludge C02F 1/72 (20130101) C02F 1/281 (20130101) C02F 1/285 (20130101) C02F 1/288 (20130101) C02F 1/705 (20130101) C02F 1/5245 (20130101) C02F 2101/16 (20130101) C02F 2101/105 (20130101) C02F 2101/163 (20130101) C02F 2103/001 (20130101) C02F 2103/06 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
Government Rights Acknowledged
| US 11236637 | Parnin et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Francis Parnin (Suffield, Connecticut); Anthony Spagnoletti (Newington, Connecticut) |
| ABSTRACT | A lubrication system is disclosed. In various embodiments, the lubrication system includes a storage tank configured to store a lubricant; a flow management valve configured to direct the lubricant to a starvation tolerant component and to a valve exit conduit; and a main pump configured to receive the lubricant from the storage tank and to pump the lubricant to the flow management valve and to a starvation intolerant component. |
| FILED | Friday, December 21, 2018 |
| APPL NO | 16/230711 |
| ART UNIT | 3654 — Material and Article Handling |
| CURRENT CPC | Non-positive Displacement Machines or Engines, e.g Steam Turbines F01D 25/20 (20130101) Original (OR) Class Lubricating of Machines or Engines in General; Lubricating Internal Combustion Engines; Crankcase Ventilating F01M 11/067 (20130101) Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/06 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2260/98 (20130101) F05D 2270/301 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11236677 | Hough et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | UNITED TECHNOLOGIES CORPORATION (Farmington, Connecticut) |
| ASSIGNEE(S) | Raytheon Technologies Corporation (Farmington, Connecticut) |
| INVENTOR(S) | Matthew Andrew Hough (West Simsbury, Connecticut); John S. Tu (Agawam, Massachusetts); Stephen C. Harmon (East Hampton, Connecticut); Paul F. Croteau (Columbia, Connecticut); Russell B. Hanson (Jupiter, Florida); Joshua C. Rathgeb (Glastonbury, Connecticut) |
| ABSTRACT | A diffuser case support structure for a gas turbine engine includes a fairing disposed circumferentially about a longitudinal axis. The fairing defines a plurality of passages circumferentially spaced apart and forming at least a portion of a fluid path between a compressor and a combustor of the gas turbine engine. A diffuser frame includes a plurality of struts. Each of the plurality of struts is disposed between a pair of adjacent passages of the plurality of passages. The diffuser frame is configured to couple an inner diffuser case to an outer diffuser case. A sliding joint is formed between the fairing and the diffuser frame, the sliding joint comprising a fastener extending generally axially through an aperture disposed in the fairing. |
| FILED | Wednesday, May 15, 2019 |
| APPL NO | 16/413347 |
| ART UNIT | 3745 — Thermal & Combustion Technology, Motive & Fluid Power Systems |
| CURRENT CPC | Gas-turbine Plants; Air Intakes for Jet-propulsion Plants; Controlling Fuel Supply in Air-breathing Jet-propulsion Plants F02C 7/28 (20130101) Original (OR) Class F02C 7/32 (20130101) Indexing Scheme for Aspects Relating to Non-positive-displacement Machines or Engines, Gas-turbines or Jet-propulsion Plants F05D 2220/32 (20130101) F05D 2240/55 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
| US 11237117 | Havener et al. |
|---|---|
| FUNDED BY |
|
| APPLICANT(S) | BWXT Nuclear Operations Group, Inc. (Lynchburg, Virginia); BWXT NOG Technologies, Inc. (Lynchburg, Virginia); Aaron C. Havener (Pittsburgh, Pennsylvania) |
| ASSIGNEE(S) | BWXT Nuclear Operations Group, Inc. (Lynchburg, Virginia); BWXT NOG Technologies, Inc. (Lynchburg, Virginia) |
| INVENTOR(S) | Aaron C. Havener (Pittsburgh, Pennsylvania); James D. Jogerst (Forest, Virginia); Thomas C. Mohr (Forest, Virginia); Keith B. Rider (Prospect, Virginia) |
| ABSTRACT | Methods of and apparatus for inspecting composite layers of a first material formed on a second material are provided including providing an illumination source, illuminating at least a portion of the composite at the layer, receiving light reflected from the sample, determining a spectral response from the received light, and comparing the received spectral response to an expected spectral response. |
| FILED | Monday, August 31, 2020 |
| APPL NO | 17/008103 |
| ART UNIT | 2882 — Optics |
| CURRENT CPC | Investigating or Analysing Materials by Determining Their Chemical or Physical Properties G01N 21/94 (20130101) G01N 21/8806 (20130101) Original (OR) Class G01N 2021/8812 (20130101) G01N 2021/8835 (20130101) |
| VIEW PATENT | @ USPTO: Full Text PDF |
How To Use This Page
THE FEDINVENT PATENT DETAILS PAGE
Each week, FedInvent analyzes newly granted patents and published patent applications whose origins lead back to funding by the US Federal Government. The FedInvent Patent Details page is a companion to the weekly FedInvents Patents Report.
This week's information is published in the FedInvent Patents report for Tuesday, February 01, 2022.
The FedInvent Weekly Patent Details Page contains a subset of patent information to provide a deeper dive into the week’s taxpayer-funded patents to help the reader better understand where a patent fits in the federal innovation ecosphere.
HOW IS THE INFORMATION ORGANIZED?
Patents are organized by the funding agency. Within each group, the patents are organized in numeric order. A patent funded by more than one agency will appear in the section of each of the agencies that funded the research and development that resulted in the invention. This approach gives the reader a complete view of the department or agency activity for the week.
WHAT INFORMATION WILL I FIND?
THE PANEL
There is a panel for each patent that contains the patent number and the title of the patent. When you click the panel, it opens to reveal the following information:
FUNDED BY
The agencies that funded the grants, contracts, or other research agreements that resulted in the patent. FedInvent includes as much information on the source of the funding as possible. The information is presented in a hierarchy going from the Federal Department down to the agencies, subagencies, and offices that funded the work. Here are two examples:
Department of Health and Human Services (HHS)
National Institutes of Health (NIH)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Department of Defense (DOD)
Defense Advanced Research Projects Agency (DARPA)
Army Research Office (ARO)
We do our best to provide detailed information about the funding. In some cases, the patent only reports limited information on the origins of the funding. FedInvents presents what it can confirm. We add the patents without the information required by the Bayh-Dole Act to our list of patents worthy of further investigation.
APPLICANT(S) and ASSIGNEES
FedInvent includes both the Applicants and the Assignees because having both provides more information about where the inventive work was done and by what organizations. Many organizations — universities, corporations, and federal agencies — standardize the Assignee/Owner information by the time a patent is granted. In the case of federal patents, many of the patents use the agency headquarters information for patent assignment.
Showing just the headquarters address would make Washington, DC the epicenter of all taxpayer-funded research and development. Providing both the applicant information and the assignee information provides a more accurate picture of where important taxpayer funded innovation is happening in America. Here are two examples from two different patents:
APPLICANT: U.S. Army Research Laboratory, Adelphi, MD
ASSIGNEE: The United States of America as represented by the Secretary of the Army Washington, DC
APPLICANT: Optech Ventures, LLC (Torrance, California)
ASSIGNEE(S): The Regents of the University of California (Oakland, California); Optech Ventures, LLC (Torrance, California)
INVENTOR(S)
The inventors appear in the same order as they appear on the patent. FedInvents presents the names in first name/last name order because they are easier to read than the last name/first name order of the names on the USPTO patent documents.
ABSTRACT
The abstract as it appears on the patent.
FILED
The date of the patent application including the day of the week.
APPL NO
This is the patent application serial number. If you’d like to learn more about how application serial numbers work you can go to the Lists Page.
ART UNIT
Patent data includes the Art Unit where a patent was examined. (The Art Unit isn’t available for published patent applications.) The Art Unit provides insight into what group of patent examiners prosecuted the patent application and the subject matter that the examiners work on. For example:
3793 — Medical Instruments, Diagnostic Equipment, and Treatment Devices
You can learn more about ART UNITS on the FedInvent Patents Weekly panel called About Tech Center or you can find information on the FedInvent Lists Page.
CURRENT CPC
Current CPC provides a list of the Cooperative Patent Classification symbols assigned to the patent. These are the CPC symbols assigned at the time the patent was granted.
The FedInvent Project is a patent classification maximalist endeavor or put another way, we believe that more you understand about patent classification the more you'll learn about the nature of the invention and the types of work that the federal government is funding.
The symbol presented in BOLD is the symbol identified as the "first" classification which is the most relevant classification on the patent. The date that follows the symbol is the date of the most recent revision to the art classed there.
- A61B 1/149 (20130101)
- A61B 1/71 (20130101)
- A61B 1/105 (20130101)
The CPC symbols match the classifications found on the PDF version of the patent. Over time, the classifications on the full-text version of the patent change to reflect how USPTO organizes patent art to support its examiners. The two sets of CPCs don’t always match.
VIEW PATENT
As of June 2021, we include two ways to view a patent at USPTO. FedInvent provides a link to the Full-Text Version of the patent and a link to the PDF version of the patent.
HOW DO I FIND A SPECIFIC PATENT ON A PAGE?
You can use the Command F or Control F to find a specific patent you are interested in.
HOW DO I GET HERE?
You navigate to the details of a patent by clicking the information icon that follows a patent on the FedInvent Patents Weekly Report.
You can also reach this page using the weekly page link that looks like this:
https://wayfinder.digital/fedinvent/patents-2022/details-patents-20220201.html
Just update the date portion of the URL. Tuesdays for patents. Thursdays for pre-grant publication of patent applications.
Download a copy of the How To Use This Page